locus-tag	class	description
IMZ86_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
IMZ86_RS00010	COG0592	DNA-directed DNA polymerase activity
IMZ86_RS00015	COG2501	S4 domain
IMZ86_RS00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
IMZ86_RS00025	COG0187	DNA topoisomerase II activity
IMZ86_RS00030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IMZ86_RS00035	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
IMZ86_RS00045	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
IMZ86_RS00055	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
IMZ86_RS00065	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
IMZ86_RS00070	COG0359	binds to the 23S rRNA
IMZ86_RS00075	COG0305	Participates in initiation and elongation during chromosome replication
IMZ86_RS00080	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
IMZ86_RS00095	COG0745	RESPONSE REGULATOR receiver
IMZ86_RS00100	COG5002	protein histidine kinase activity
IMZ86_RS00105	COG4863	YycH protein
IMZ86_RS00140	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
IMZ86_RS00145	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
IMZ86_RS00155	COG1522	sequence-specific DNA binding
IMZ86_RS00175	COG1073	alpha beta
IMZ86_RS00205	COG1129	ABC transporter
IMZ86_RS00240	COG5002	protein histidine kinase activity
IMZ86_RS00245	COG0745	RESPONSE REGULATOR receiver
IMZ86_RS00255	COG1131	(ABC) transporter
IMZ86_RS00315	COG2188	Transcriptional regulator
IMZ86_RS00320	COG2222	sugar isomerase
IMZ86_RS00325	COG3684	Belongs to the aldolase LacD family
IMZ86_RS00330	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IMZ86_RS00335	COG3715	PTS system
IMZ86_RS00340	COG3716	PTS system mannose fructose sorbose family IID component
IMZ86_RS00350	COG0745	RESPONSE REGULATOR receiver
IMZ86_RS00355	COG2205	protein histidine kinase activity
IMZ86_RS00365	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
IMZ86_RS00370	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
IMZ86_RS00395	COG1129	ABC transporter
IMZ86_RS00430	COG4509	Sortase family
IMZ86_RS00440	COG1705	Flagellar rod assembly protein muramidase FlgJ
IMZ86_RS00440	COG3942	CHAP domain
IMZ86_RS00445	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IMZ86_RS00450	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IMZ86_RS00455	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
IMZ86_RS00460	COG2808	Putative FMN-binding domain
IMZ86_RS00470	COG1846	Transcriptional regulator
IMZ86_RS00480	COG3842	ATPase activity
IMZ86_RS00485	COG4209	transmembrane transport
IMZ86_RS00495	COG0395	ABC-type sugar transport system, permease component
IMZ86_RS00505	COG0534	Mate efflux family protein
IMZ86_RS00510	COG1349	DNA-binding transcription factor activity
IMZ86_RS00520	COG5002	protein histidine kinase activity
IMZ86_RS00560	COG0583	DNA-binding transcription factor activity
IMZ86_RS00565	COG3842	ATPase activity
IMZ86_RS00570	COG1840	ABC-type Fe3 transport system, periplasmic component
IMZ86_RS00575	COG1177	transmembrane transport
IMZ86_RS00580	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
IMZ86_RS00585	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
IMZ86_RS00595	COG1114	Component of the transport system for branched-chain amino acids
IMZ86_RS00610	COG0464	growth
IMZ86_RS00615	COG0561	phosphatase activity
IMZ86_RS00620	COG2814	Major facilitator Superfamily
IMZ86_RS00635	COG0601	transmembrane transport
IMZ86_RS00645	COG0444	Belongs to the ABC transporter superfamily
IMZ86_RS00650	COG1124	(ABC) transporter
IMZ86_RS00665	COG0693	protein deglycase activity
IMZ86_RS00670	COG0531	amino acid
IMZ86_RS00675	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IMZ86_RS00675	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IMZ86_RS00680	COG0505	Belongs to the CarA family
IMZ86_RS00685	COG0657	acetylesterase activity
IMZ86_RS00725	COG2409	Drug exporters of the RND superfamily
IMZ86_RS00725	COG1033	growth of symbiont in host cell
IMZ86_RS00745	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
IMZ86_RS00760	COG1131	(ABC) transporter
IMZ86_RS00775	COG1028	Short-chain dehydrogenase reductase Sdr
IMZ86_RS00780	COG1278	Cold shock
IMZ86_RS00795	COG2311	Membrane
IMZ86_RS00800	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
IMZ86_RS00830	COG2814	Major facilitator Superfamily
IMZ86_RS00845	COG1131	(ABC) transporter
IMZ86_RS00870	COG2264	protein methyltransferase activity
IMZ86_RS00875	COG0747	negative chemotaxis
IMZ86_RS00880	COG0601	transmembrane transport
IMZ86_RS00890	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
IMZ86_RS00895	COG1124	(ABC) transporter
IMZ86_RS00900	COG3961	Belongs to the TPP enzyme family
IMZ86_RS00915	COG1131	(ABC) transporter
IMZ86_RS00925	COG2353	YceI-like domain
IMZ86_RS00930	COG1288	antiporter activity
IMZ86_RS00940	COG2814	Major facilitator Superfamily
IMZ86_RS00960	COG1028	Short-chain dehydrogenase reductase Sdr
IMZ86_RS00970	COG1263	PTS System
IMZ86_RS00970	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IMZ86_RS00970	COG2190	(PTS) system
IMZ86_RS00975	COG1028	Short-chain dehydrogenase reductase Sdr
IMZ86_RS01000	COG3976	FMN-binding domain protein
IMZ86_RS01000	COG0431	NADPH-dependent FMN reductase
IMZ86_RS01000	COG1053	succinate dehydrogenase
IMZ86_RS01015	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
IMZ86_RS01025	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IMZ86_RS01030	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
IMZ86_RS01035	COG0022	dehydrogenase e1 component
IMZ86_RS01045	COG1695	Transcriptional regulator
IMZ86_RS01065	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
IMZ86_RS01065	COG3711	transcriptional antiterminator
IMZ86_RS01070	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
IMZ86_RS01070	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IMZ86_RS01070	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IMZ86_RS01075	COG1482	cell wall glycoprotein biosynthetic process
IMZ86_RS01080	COG2124	cytochrome p450
IMZ86_RS01090	COG1846	Transcriptional regulator
IMZ86_RS01095	COG2814	Major facilitator Superfamily
IMZ86_RS01120	COG0706	membrane insertase activity
IMZ86_RS01130	COG0531	amino acid
IMZ86_RS01185	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IMZ86_RS01210	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
IMZ86_RS01220	COG0363	glucosamine-6-phosphate deaminase activity
IMZ86_RS01225	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
IMZ86_RS01240	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IMZ86_RS01245	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IMZ86_RS01250	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
IMZ86_RS01285	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
IMZ86_RS01305	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
IMZ86_RS01310	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
IMZ86_RS01310	COG3711	transcriptional antiterminator
IMZ86_RS01315	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
IMZ86_RS01330	COG1054	Belongs to the UPF0176 family
IMZ86_RS01335	COG3386	PFAM SMP-30 Gluconolaconase
IMZ86_RS01350	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IMZ86_RS01360	COG1122	ATPase activity
IMZ86_RS01370	COG1476	TRANSCRIPTIONal
IMZ86_RS01400	COG1705	Flagellar rod assembly protein muramidase FlgJ
IMZ86_RS01400	COG3942	CHAP domain
IMZ86_RS01425	COG4974	Belongs to the 'phage' integrase family
IMZ86_RS01455	COG3682	Transcriptional regulator
IMZ86_RS01460	COG2235	arginine
IMZ86_RS01470	COG2843	Capsule synthesis protein
IMZ86_RS01475	COG4195	phage-related replication protein
IMZ86_RS01480	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
IMZ86_RS01520	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
IMZ86_RS01555	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
IMZ86_RS01560	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
IMZ86_RS01565	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
IMZ86_RS01570	COG1785	Belongs to the alkaline phosphatase family
IMZ86_RS01585	COG2205	protein histidine kinase activity
IMZ86_RS01590	COG1136	(ABC) transporter
IMZ86_RS01620	COG1028	Short-chain dehydrogenase reductase Sdr
IMZ86_RS01625	COG4932	domain protein
IMZ86_RS01625	COG3266	domain, Protein
IMZ86_RS01625	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
IMZ86_RS01625	COG4932	domain protein
IMZ86_RS01625	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
IMZ86_RS01625	COG3266	domain, Protein
IMZ86_RS01635	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
IMZ86_RS01640	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IMZ86_RS01655	COG0730	response to heat
IMZ86_RS01660	COG2046	Belongs to the sulfate adenylyltransferase family
IMZ86_RS01665	COG0529	Catalyzes the synthesis of activated sulfate
IMZ86_RS01680	COG1328	CTP reductase activity
IMZ86_RS01685	COG0602	queuosine metabolic process
IMZ86_RS01690	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
IMZ86_RS01695	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
IMZ86_RS01700	COG1510	regulation of RNA biosynthetic process
IMZ86_RS01705	COG1012	belongs to the aldehyde dehydrogenase family
IMZ86_RS01710	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
IMZ86_RS01715	COG1473	amidohydrolase
IMZ86_RS01730	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
IMZ86_RS01735	COG0574	Belongs to the PEP-utilizing enzyme family
IMZ86_RS01735	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IMZ86_RS01740	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
IMZ86_RS01750	COG2188	Transcriptional regulator
IMZ86_RS01755	COG1263	PTS System
IMZ86_RS01755	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IMZ86_RS01755	COG2190	(PTS) system
IMZ86_RS01760	COG2723	6-phospho-beta-galactosidase activity
IMZ86_RS01770	COG0583	DNA-binding transcription factor activity
IMZ86_RS01785	COG3588	fructose-bisphosphate aldolase
IMZ86_RS01800	COG1464	Belongs to the NlpA lipoprotein family
IMZ86_RS01810	COG0463	Glycosyl transferase, family 2
IMZ86_RS01820	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
IMZ86_RS01820	COG1215	transferase activity, transferring glycosyl groups
IMZ86_RS01830	COG0531	amino acid
IMZ86_RS01835	COG0583	DNA-binding transcription factor activity
IMZ86_RS01840	COG0028	Belongs to the TPP enzyme family
IMZ86_RS01845	COG3527	Alpha-acetolactate decarboxylase
IMZ86_RS01850	COG1620	l-lactate permease
IMZ86_RS01870	COG0167	dihydroorotate dehydrogenase activity
IMZ86_RS01875	COG3001	Fructosamine kinase
IMZ86_RS01880	COG0596	Alpha beta hydrolase
IMZ86_RS01930	COG2814	Major facilitator Superfamily
IMZ86_RS01940	COG1113	amino acid transport
IMZ86_RS01950	COG3189	MarR family transcriptional regulator
IMZ86_RS01970	COG0436	Aminotransferase
IMZ86_RS01980	COG2608	mercury ion transmembrane transporter activity
IMZ86_RS01985	COG2217	Heavy metal translocating P-type atpase
IMZ86_RS01995	COG0110	maltose O-acetyltransferase activity
IMZ86_RS02000	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
IMZ86_RS02005	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
IMZ86_RS02010	COG1012	belongs to the aldehyde dehydrogenase family
IMZ86_RS02020	COG2409	Drug exporters of the RND superfamily
IMZ86_RS02030	COG0598	Magnesium transport protein CorA
IMZ86_RS02035	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
IMZ86_RS02060	COG1131	(ABC) transporter
IMZ86_RS02070	COG3425	synthase
IMZ86_RS02085	COG1388	LysM domain
IMZ86_RS02085	COG3942	CHAP domain
IMZ86_RS02095	COG0583	DNA-binding transcription factor activity
IMZ86_RS02100	COG1380	Effector of murein hydrolase LrgA
IMZ86_RS02105	COG1346	cytolysis
IMZ86_RS02110	COG0028	Belongs to the TPP enzyme family
IMZ86_RS02125	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
IMZ86_RS02130	COG0039	L-malate dehydrogenase activity
IMZ86_RS02135	COG0657	acetylesterase activity
IMZ86_RS02145	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
IMZ86_RS02170	COG1070	Carbohydrate kinase
IMZ86_RS02180	COG1760	l-serine dehydratase
IMZ86_RS02185	COG1760	l-serine dehydratase
IMZ86_RS02195	COG3764	Sortase (surface protein transpeptidase)
IMZ86_RS02205	COG0561	phosphatase activity
IMZ86_RS02210	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IMZ86_RS02215	COG0778	Nitroreductase
IMZ86_RS02225	COG1012	belongs to the aldehyde dehydrogenase family
IMZ86_RS02230	COG2514	catechol 2,3-dioxygenase activity
IMZ86_RS02235	COG2388	GCN5-related N-acetyl-transferase
IMZ86_RS02250	COG1846	Transcriptional regulator
IMZ86_RS02255	COG0346	lactoylglutathione lyase activity
IMZ86_RS02260	COG0346	lactoylglutathione lyase activity
IMZ86_RS02265	COG0400	carboxylic ester hydrolase activity
IMZ86_RS02270	COG3949	Membrane
IMZ86_RS02280	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
IMZ86_RS02285	COG0586	Pfam SNARE associated Golgi protein
IMZ86_RS02295	COG2022	thiamine diphosphate biosynthetic process
IMZ86_RS02315	COG2271	Major facilitator Superfamily
IMZ86_RS02330	COG4876	unkown
IMZ86_RS02335	COG2357	RelA SpoT domain protein
IMZ86_RS02350	COG1802	Transcriptional regulator
IMZ86_RS02355	COG1070	Carbohydrate kinase
IMZ86_RS02360	COG2610	gluconate transmembrane transporter activity
IMZ86_RS02365	COG1210	Utp--glucose-1-phosphate uridylyltransferase
IMZ86_RS02375	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IMZ86_RS02380	COG0438	transferase activity, transferring glycosyl groups
IMZ86_RS02385	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IMZ86_RS02400	COG4221	oxidoreductase activity
IMZ86_RS02405	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
IMZ86_RS02410	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
IMZ86_RS02420	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
IMZ86_RS02425	COG1363	Peptidase, m42
IMZ86_RS02445	COG3639	organic phosphonate transmembrane transporter activity
IMZ86_RS02450	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
IMZ86_RS02465	COG0737	Belongs to the 5'-nucleotidase family
IMZ86_RS02470	COG0069	glutamate synthase activity
IMZ86_RS02485	COG4619	ABC transporter
IMZ86_RS02490	COG0390	transport system, permease component
IMZ86_RS02495	COG2205	protein histidine kinase activity
IMZ86_RS02500	COG0745	RESPONSE REGULATOR receiver
IMZ86_RS02510	COG2814	Major facilitator Superfamily
IMZ86_RS02515	COG2272	Belongs to the type-B carboxylesterase lipase family
IMZ86_RS02520	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
IMZ86_RS02525	COG1063	alcohol dehydrogenase
IMZ86_RS02545	COG1174	glycine betaine transport
IMZ86_RS02575	COG1346	cytolysis
IMZ86_RS02580	COG1380	Effector of murein hydrolase LrgA
IMZ86_RS02585	COG3279	Response regulator of the LytR AlgR family
IMZ86_RS02590	COG3275	phosphorelay sensor kinase activity
IMZ86_RS02600	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
IMZ86_RS02605	COG0456	acetyltransferase
IMZ86_RS02615	COG0706	membrane insertase activity
IMZ86_RS02625	COG0531	amino acid
IMZ86_RS02640	COG1113	amino acid transport
IMZ86_RS02660	COG2814	Major facilitator Superfamily
IMZ86_RS02670	COG1929	Belongs to the glycerate kinase type-1 family
IMZ86_RS02680	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
IMZ86_RS02685	COG0741	lytic transglycosylase activity
IMZ86_RS02690	COG0588	phosphoglycerate mutase activity
IMZ86_RS02700	COG2814	Major facilitator Superfamily
IMZ86_RS02705	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IMZ86_RS02710	COG0765	amino acid transport
IMZ86_RS02715	COG1126	abc transporter atp-binding protein
IMZ86_RS02755	COG1131	(ABC) transporter
IMZ86_RS02765	COG2116	formate transmembrane transporter activity
IMZ86_RS02775	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IMZ86_RS02780	COG2146	nitrite reductase [NAD(P)H] activity
IMZ86_RS02790	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
IMZ86_RS02795	COG1140	nitrate reductase beta subunit
IMZ86_RS02805	COG2181	nitrate reductase activity
IMZ86_RS02815	COG4585	Histidine kinase
IMZ86_RS02825	COG2223	nitrite transmembrane transporter activity
IMZ86_RS02830	COG1846	Transcriptional regulator
IMZ86_RS02870	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IMZ86_RS02870	COG1263	PTS System
IMZ86_RS02895	COG0534	Mate efflux family protein
IMZ86_RS02905	COG1124	(ABC) transporter
IMZ86_RS02910	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
IMZ86_RS02920	COG0601	transmembrane transport
IMZ86_RS02930	COG0829	nickel cation binding
IMZ86_RS02945	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
IMZ86_RS02950	COG0804	urea catabolic process
IMZ86_RS02960	COG0831	urea catabolic process
IMZ86_RS02965	COG4413	Urea transporter
IMZ86_RS02975	COG4716	Myosin-crossreactive antigen
IMZ86_RS02980	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
IMZ86_RS02985	COG2962	Rard protein
IMZ86_RS03030	COG2814	Major facilitator Superfamily
IMZ86_RS03035	COG0583	DNA-binding transcription factor activity
IMZ86_RS03075	COG2314	TM2 domain
IMZ86_RS03080	COG0492	ferredoxin-NADP+ reductase activity
IMZ86_RS03095	COG0604	alcohol dehydrogenase
IMZ86_RS03100	COG2822	iron ion transport
IMZ86_RS03105	COG2837	iron assimilation
IMZ86_RS03110	COG0672	)-iron permease
IMZ86_RS03115	COG0805	protein transport
IMZ86_RS03120	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
IMZ86_RS03125	COG0456	acetyltransferase
IMZ86_RS03135	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
IMZ86_RS03140	COG1620	l-lactate permease
IMZ86_RS03145	COG0297	glycogen (starch) synthase activity
IMZ86_RS03150	COG0579	oxidoreductase
IMZ86_RS03200	COG2814	Major facilitator Superfamily
IMZ86_RS03210	COG1566	PFAM secretion protein HlyD family protein
IMZ86_RS03215	COG2814	Major facilitator Superfamily
IMZ86_RS03240	COG0598	Magnesium transport protein CorA
IMZ86_RS03245	COG1304	FMN binding
IMZ86_RS03250	COG2094	Belongs to the DNA glycosylase MPG family
IMZ86_RS03260	COG2017	converts alpha-aldose to the beta-anomer
IMZ86_RS03265	COG2258	MOSC domain
IMZ86_RS03270	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
IMZ86_RS03275	COG1266	CAAX protease self-immunity
IMZ86_RS03285	COG1028	Short-chain dehydrogenase reductase Sdr
IMZ86_RS03305	COG1737	Transcriptional regulator
IMZ86_RS03310	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IMZ86_RS03310	COG1263	PTS System
IMZ86_RS03320	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
IMZ86_RS03340	COG1113	amino acid transport
IMZ86_RS03345	COG1737	Transcriptional regulator
IMZ86_RS03350	COG1263	PTS System
IMZ86_RS03350	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IMZ86_RS03355	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
IMZ86_RS03365	COG1349	DNA-binding transcription factor activity
IMZ86_RS03375	COG1316	TRANSCRIPTIONal
IMZ86_RS03400	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IMZ86_RS03405	COG2076	Multidrug Resistance protein
IMZ86_RS03410	COG2076	Multidrug Resistance protein
IMZ86_RS03415	COG3942	CHAP domain
IMZ86_RS03430	COG1757	Na H antiporter
IMZ86_RS03435	COG3942	CHAP domain
IMZ86_RS03465	COG1960	acyl-CoA dehydrogenase activity
IMZ86_RS03470	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
IMZ86_RS03480	COG1268	BioY protein
IMZ86_RS03490	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
IMZ86_RS03495	COG0725	ABC transporter, periplasmic molybdate-binding protein
IMZ86_RS03500	COG4149	molybdate abc transporter
IMZ86_RS03505	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
IMZ86_RS03510	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
IMZ86_RS03545	COG0746	molybdenum cofactor guanylyltransferase activity
IMZ86_RS03550	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
IMZ86_RS03575	COG2348	transferase activity, transferring amino-acyl groups
IMZ86_RS03580	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IMZ86_RS03610	COG2252	PERMEase
IMZ86_RS03625	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
IMZ86_RS03630	COG0088	Forms part of the polypeptide exit tunnel
IMZ86_RS03635	COG0089	rRNA binding
IMZ86_RS03640	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
IMZ86_RS03645	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
IMZ86_RS03655	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
IMZ86_RS03660	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
IMZ86_RS03670	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
IMZ86_RS03680	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
IMZ86_RS03695	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
IMZ86_RS03700	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
IMZ86_RS03705	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
IMZ86_RS03710	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
IMZ86_RS03715	COG1841	ribosomal large subunit assembly
IMZ86_RS03725	COG0201	protein transport
IMZ86_RS03730	COG0563	adenylate kinase activity
IMZ86_RS03735	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
IMZ86_RS03740	COG0257	Belongs to the bacterial ribosomal protein bL36 family
IMZ86_RS03745	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
IMZ86_RS03755	COG0202	RNA polymerase activity
IMZ86_RS03760	COG0203	ribosomal protein L17
IMZ86_RS03770	COG1122	ATPase activity
IMZ86_RS03780	COG0101	tRNA pseudouridine synthase activity
IMZ86_RS03785	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
IMZ86_RS03805	COG1131	(ABC) transporter
IMZ86_RS03815	COG1131	(ABC) transporter
IMZ86_RS03825	COG1309	transcriptional regulator
IMZ86_RS03865	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
IMZ86_RS03870	COG1349	DNA-binding transcription factor activity
IMZ86_RS03875	COG0698	ribose 5-phosphate isomerase
IMZ86_RS03880	COG0698	ribose 5-phosphate isomerase
IMZ86_RS03885	COG1105	Belongs to the carbohydrate kinase PfkB family
IMZ86_RS03890	COG3684	Belongs to the aldolase LacD family
IMZ86_RS03895	COG1447	Phosphotransferase system cellobiose-specific component IIA
IMZ86_RS03900	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
IMZ86_RS03900	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
IMZ86_RS03905	COG2723	6-phospho-beta-galactosidase activity
IMZ86_RS03915	COG2130	NADP-dependent
IMZ86_RS03920	COG0604	alcohol dehydrogenase
IMZ86_RS03950	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
IMZ86_RS03955	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IMZ86_RS03960	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IMZ86_RS03965	COG3314	Sporulation integral membrane protein YlbJ
IMZ86_RS03975	COG1988	membrane-bound metal-dependent
IMZ86_RS03980	COG4284	Utp--glucose-1-phosphate uridylyltransferase
IMZ86_RS03985	COG1272	protein, Hemolysin III
IMZ86_RS04000	COG2814	Major facilitator Superfamily
IMZ86_RS04005	COG0489	protein tyrosine kinase activity
IMZ86_RS04075	COG0561	phosphatase activity
IMZ86_RS04095	COG0640	Transcriptional regulator
IMZ86_RS04100	COG0702	epimerase
IMZ86_RS04105	COG1482	cell wall glycoprotein biosynthetic process
IMZ86_RS04125	COG0783	Belongs to the Dps family
IMZ86_RS04130	COG0813	purine-nucleoside phosphorylase activity
IMZ86_RS04135	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
IMZ86_RS04140	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
IMZ86_RS04145	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
IMZ86_RS04170	COG1854	S-ribosylhomocysteine lyase activity
IMZ86_RS04190	COG5146	pantothenate kinase activity
IMZ86_RS04200	COG3343	RNA polymerase activity
IMZ86_RS04205	COG0504	CTP synthase activity
IMZ86_RS04215	COG0191	fructose-bisphosphate aldolase activity
IMZ86_RS04220	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
IMZ86_RS04230	COG1012	belongs to the aldehyde dehydrogenase family
IMZ86_RS04235	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
IMZ86_RS04240	COG0254	rRNA binding
IMZ86_RS04250	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
IMZ86_RS04255	COG2890	protein-(glutamine-N5) methyltransferase activity
IMZ86_RS04260	COG0009	L-threonylcarbamoyladenylate synthase
IMZ86_RS04270	COG4475	Protein of unknown function (DUF436)
IMZ86_RS04275	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
IMZ86_RS04290	COG0356	it plays a direct role in the translocation of protons across the membrane
IMZ86_RS04295	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
IMZ86_RS04300	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
IMZ86_RS04305	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
IMZ86_RS04315	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
IMZ86_RS04320	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
IMZ86_RS04330	COG4836	Membrane
IMZ86_RS04335	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
IMZ86_RS04340	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
IMZ86_RS04375	COG0629	single-stranded DNA binding
IMZ86_RS04385	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
IMZ86_RS04395	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
IMZ86_RS04400	COG0352	thiamine-phosphate diphosphorylase activity
IMZ86_RS04405	COG0706	membrane insertase activity
IMZ86_RS04410	COG1418	mRNA catabolic process
IMZ86_RS04415	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IMZ86_RS04420	COG1937	Protein conserved in bacteria
IMZ86_RS04435	COG0772	Belongs to the SEDS family
IMZ86_RS04440	COG1181	Belongs to the D-alanine--D-alanine ligase family
IMZ86_RS04445	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
IMZ86_RS04450	COG0513	Belongs to the DEAD box helicase family
IMZ86_RS04460	COG3428	Bacterial PH domain
IMZ86_RS04470	COG0736	holo-[acyl-carrier-protein] synthase activity
IMZ86_RS04485	COG2337	Toxic component of a toxin-antitoxin (TA) module
IMZ86_RS04490	COG2208	phosphoserine phosphatase activity
IMZ86_RS04505	COG1191	sigma factor activity
IMZ86_RS04510	COG2183	response to ionizing radiation
IMZ86_RS04550	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
IMZ86_RS04560	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
IMZ86_RS04570	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
IMZ86_RS04575	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
IMZ86_RS04585	COG0028	Belongs to the TPP enzyme family
IMZ86_RS04595	COG0802	atpase or kinase
IMZ86_RS04600	COG1214	PFAM Peptidase M22, glycoprotease
IMZ86_RS04605	COG0456	acetyltransferase
IMZ86_RS04610	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
IMZ86_RS04615	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
IMZ86_RS04620	COG0488	(ABC) transporter
IMZ86_RS04625	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
IMZ86_RS04630	COG2391	methyltransferase activity
IMZ86_RS04635	COG0425	Belongs to the sulfur carrier protein TusA family
IMZ86_RS04640	COG0004	ammonium transporteR
IMZ86_RS04645	COG1609	Transcriptional regulator
IMZ86_RS04650	COG1621	beta-fructofuranosidase activity
IMZ86_RS04655	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IMZ86_RS04665	COG3290	protein histidine kinase activity
IMZ86_RS04675	COG4512	PFAM Accessory gene regulator B
IMZ86_RS04680	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
IMZ86_RS04705	COG0459	protein refolding
IMZ86_RS04710	COG0436	Aminotransferase
IMZ86_RS04720	COG1725	Transcriptional regulator
IMZ86_RS04725	COG1129	ABC transporter
IMZ86_RS04725	COG0842	Transport permease protein
IMZ86_RS04735	COG1131	(ABC) transporter
IMZ86_RS04775	COG2706	6-phosphogluconolactonase activity
IMZ86_RS04780	COG1012	belongs to the aldehyde dehydrogenase family
IMZ86_RS04785	COG1227	inorganic diphosphatase activity
IMZ86_RS04790	COG1335	isochorismatase
IMZ86_RS04805	COG0077	Prephenate dehydratase
IMZ86_RS04815	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
IMZ86_RS04820	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
IMZ86_RS04825	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
IMZ86_RS04835	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
IMZ86_RS04840	COG4496	protein, YerC YecD
IMZ86_RS04845	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
IMZ86_RS04855	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
IMZ86_RS04860	COG4851	CamS sex pheromone cAM373 precursor
IMZ86_RS04870	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IMZ86_RS04880	COG0154	amidase activity
IMZ86_RS04885	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IMZ86_RS04890	COG1597	lipid kinase activity
IMZ86_RS04895	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IMZ86_RS04920	COG1528	Iron-storage protein
IMZ86_RS04940	COG0446	pyridine nucleotide-disulphide oxidoreductase
IMZ86_RS04945	COG4129	membrane
IMZ86_RS04950	COG0024	Methionine aminopeptidase
IMZ86_RS04975	COG1295	ribonuclease BN
IMZ86_RS04985	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IMZ86_RS04990	COG4840	Belongs to the UPF0435 family
IMZ86_RS04995	COG2309	aminopeptidase activity
IMZ86_RS05000	COG1607	acyl-coa hydrolase
IMZ86_RS05005	COG0535	radical SAM domain protein
IMZ86_RS05015	COG0693	protein deglycase activity
IMZ86_RS05020	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
IMZ86_RS05025	COG2137	regulation of response to DNA damage stimulus
IMZ86_RS05035	COG1388	LysM domain
IMZ86_RS05035	COG1134	teichoic acid transport
IMZ86_RS05045	COG1988	membrane-bound metal-dependent
IMZ86_RS05050	COG1194	a g-specific adenine glycosylase
IMZ86_RS05055	COG3557	Belongs to the UPF0374 family
IMZ86_RS05065	COG4129	membrane
IMZ86_RS05070	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
IMZ86_RS05075	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
IMZ86_RS05085	COG0735	belongs to the Fur family
IMZ86_RS05255	COG0765	amino acid transport
IMZ86_RS05260	COG1126	abc transporter atp-binding protein
IMZ86_RS05265	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
IMZ86_RS05275	COG0363	glucosamine-6-phosphate deaminase activity
IMZ86_RS05290	COG0114	fumarate hydratase activity
IMZ86_RS05295	COG0564	pseudouridine synthase activity
IMZ86_RS05300	COG4585	Histidine kinase
IMZ86_RS05300	COG2203	Gaf domain
IMZ86_RS05305	COG2197	response regulator
IMZ86_RS05320	COG3679	Belongs to the UPF0342 family
IMZ86_RS05325	COG0420	3'-5' exonuclease activity
IMZ86_RS05345	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
IMZ86_RS05360	COG0537	adenosine 5'-monophosphoramidase activity
IMZ86_RS05365	COG1131	(ABC) transporter
IMZ86_RS05370	COG4473	ABC transporter
IMZ86_RS05375	COG2329	Antibiotic biosynthesis monooxygenase
IMZ86_RS05380	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
IMZ86_RS05390	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
IMZ86_RS05395	COG3545	Serine hydrolase
IMZ86_RS05445	COG0318	PFAM AMP-dependent synthetase and ligase
IMZ86_RS05455	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
IMZ86_RS05465	COG1506	peptidase
IMZ86_RS05470	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
IMZ86_RS05475	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
IMZ86_RS05485	COG0656	L-ascorbic acid biosynthetic process
IMZ86_RS05490	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
IMZ86_RS05505	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
IMZ86_RS05530	COG5632	N-Acetylmuramoyl-L-alanine amidase
IMZ86_RS05530	COG4193	domain, Protein
IMZ86_RS05530	COG3266	domain, Protein
IMZ86_RS05540	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
IMZ86_RS05540	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
IMZ86_RS05550	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
IMZ86_RS05550	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
IMZ86_RS05555	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
IMZ86_RS05560	COG0506	proline dehydrogenase activity
IMZ86_RS05565	COG2267	carboxylic ester hydrolase activity
IMZ86_RS05575	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
IMZ86_RS05580	COG1242	4 iron, 4 sulfur cluster binding
IMZ86_RS05585	COG2814	Major facilitator Superfamily
IMZ86_RS05590	COG0495	leucyl-tRNA aminoacylation
IMZ86_RS05600	COG2081	HI0933 family
IMZ86_RS05605	COG2244	polysaccharide biosynthetic process
IMZ86_RS05610	COG1187	pseudouridine synthase activity
IMZ86_RS05620	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
IMZ86_RS05630	COG0510	thiamine kinase activity
IMZ86_RS05635	COG0220	tRNA (guanine-N7-)-methyltransferase activity
IMZ86_RS05640	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IMZ86_RS05645	COG5584	Small secreted protein
IMZ86_RS05650	COG1363	Peptidase, m42
IMZ86_RS05655	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
IMZ86_RS05660	COG4848	Belongs to the UPF0354 family
IMZ86_RS05665	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IMZ86_RS05670	COG1674	ftsk spoiiie
IMZ86_RS05675	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
IMZ86_RS05680	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
IMZ86_RS05690	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
IMZ86_RS05690	COG1605	Chorismate mutase
IMZ86_RS05695	COG1609	Transcriptional regulator
IMZ86_RS05710	COG0123	including yeast histone deacetylase and acetoin utilization protein
IMZ86_RS05715	COG0454	-acetyltransferase
IMZ86_RS05720	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
IMZ86_RS05725	COG2759	Belongs to the formate--tetrahydrofolate ligase family
IMZ86_RS05735	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
IMZ86_RS05740	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IMZ86_RS05745	COG0204	Acyl-transferase
IMZ86_RS05750	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IMZ86_RS05750	COG1263	PTS System
IMZ86_RS05760	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
IMZ86_RS05765	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
IMZ86_RS05770	COG1764	response to oxidative stress
IMZ86_RS05775	COG0584	glycerophosphoryl diester phosphodiesterase
IMZ86_RS05780	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
IMZ86_RS05785	COG1956	GAF domain-containing protein
IMZ86_RS05790	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
IMZ86_RS05795	COG1104	cysteine desulfurase activity
IMZ86_RS05800	COG0301	tRNA thio-modification
IMZ86_RS05805	COG0730	response to heat
IMZ86_RS05810	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
IMZ86_RS05815	COG0827	DNA restriction-modification system
IMZ86_RS05820	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
IMZ86_RS05825	COG0589	response to stress
IMZ86_RS05830	COG0686	Belongs to the AlaDH PNT family
IMZ86_RS05835	COG0006	proline dipeptidase activity
IMZ86_RS05840	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
IMZ86_RS05850	COG4109	DRTGG domain
IMZ86_RS05855	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
IMZ86_RS05860	COG0587	DNA-directed DNA polymerase activity
IMZ86_RS05865	COG0281	malic enzyme
IMZ86_RS05870	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
IMZ86_RS05875	COG0825	malonyl-CoA metabolic process
IMZ86_RS05880	COG0205	6-phosphofructokinase activity
IMZ86_RS05885	COG0469	pyruvate kinase activity
IMZ86_RS05895	COG1113	amino acid transport
IMZ86_RS05900	COG0372	Belongs to the citrate synthase family
IMZ86_RS05905	COG0538	isocitrate dehydrogenase activity
IMZ86_RS05910	COG0745	RESPONSE REGULATOR receiver
IMZ86_RS05915	COG5002	protein histidine kinase activity
IMZ86_RS05920	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IMZ86_RS05920	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IMZ86_RS05925	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
IMZ86_RS05930	COG0237	dephospho-CoA kinase activity
IMZ86_RS05935	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
IMZ86_RS05940	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
IMZ86_RS05945	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
IMZ86_RS05950	COG3611	Membrane attachment protein
IMZ86_RS05955	COG1484	DNA-dependent DNA replication
IMZ86_RS05965	COG0833	amino acid
IMZ86_RS05970	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
IMZ86_RS05975	COG0291	Belongs to the bacterial ribosomal protein bL35 family
IMZ86_RS05980	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
IMZ86_RS05985	COG4112	unkown
IMZ86_RS05995	COG0544	peptidyl-prolyl cis-trans isomerase activity
IMZ86_RS06000	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
IMZ86_RS06015	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
IMZ86_RS06020	COG0181	hydroxymethylbilane synthase activity
IMZ86_RS06035	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
IMZ86_RS06045	COG2818	Glycosylase
IMZ86_RS06050	COG0525	valine-tRNA ligase activity
IMZ86_RS06055	COG0285	dihydrofolate synthase activity
IMZ86_RS06065	COG2003	Belongs to the UPF0758 family
IMZ86_RS06080	COG1792	Involved in formation and maintenance of cell shape
IMZ86_RS06090	COG0261	This protein binds to 23S rRNA in the presence of protein L20
IMZ86_RS06095	COG2868	ribosomal protein
IMZ86_RS06105	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
IMZ86_RS06110	COG4492	Belongs to the UPF0735 family
IMZ86_RS06115	COG0632	four-way junction helicase activity
IMZ86_RS06120	COG2255	four-way junction helicase activity
IMZ86_RS06125	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
IMZ86_RS06130	COG0343	queuine tRNA-ribosyltransferase activity
IMZ86_RS06135	COG1862	Preprotein translocase
IMZ86_RS06140	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
IMZ86_RS06140	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
IMZ86_RS06155	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IMZ86_RS06160	COG1490	D-aminoacyl-tRNA deacylase activity
IMZ86_RS06165	COG0860	N-Acetylmuramoyl-L-alanine amidase
IMZ86_RS06170	COG0124	histidyl-tRNA synthetase
IMZ86_RS06175	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
IMZ86_RS06185	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
IMZ86_RS06190	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
IMZ86_RS06195	COG1959	2 iron, 2 sulfur cluster binding
IMZ86_RS06205	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IMZ86_RS06210	COG1104	cysteine desulfurase activity
IMZ86_RS06215	COG0482	sulfurtransferase activity
IMZ86_RS06225	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
IMZ86_RS06230	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
IMZ86_RS06235	COG4472	Bacterial protein of unknown function (DUF965)
IMZ86_RS06240	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
IMZ86_RS06250	COG4122	O-methyltransferase activity
IMZ86_RS06255	COG0826	peptidase U32
IMZ86_RS06260	COG0826	peptidase U32
IMZ86_RS06265	COG0572	uridine kinase
IMZ86_RS06270	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
IMZ86_RS06275	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
IMZ86_RS06280	COG1984	allophanate hydrolase subunit 2
IMZ86_RS06285	COG0511	ligase activity, forming carbon-carbon bonds
IMZ86_RS06290	COG0439	Biotin carboxylase
IMZ86_RS06300	COG1914	H( )-stimulated, divalent metal cation uptake system
IMZ86_RS06305	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
IMZ86_RS06310	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
IMZ86_RS06315	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
IMZ86_RS06325	COG1534	Rna-binding protein
IMZ86_RS06330	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
IMZ86_RS06335	COG1713	HD superfamily hydrolase involved in NAD metabolism
IMZ86_RS06340	COG0799	negative regulation of ribosome biogenesis
IMZ86_RS06345	COG2226	methyltransferase
IMZ86_RS06350	COG1555	photosystem II stabilization
IMZ86_RS06350	COG1596	polysaccharide export
IMZ86_RS06355	COG3682	Transcriptional regulator
IMZ86_RS06385	COG4974	Belongs to the 'phage' integrase family
IMZ86_RS06395	COG2131	deaminase
IMZ86_RS06400	COG2333	competence protein COMEC
IMZ86_RS06400	COG0658	competence protein
IMZ86_RS06405	COG1466	dna polymerase III delta subunit
IMZ86_RS06410	COG0268	Binds directly to 16S ribosomal RNA
IMZ86_RS06415	COG0481	GTPase activity
IMZ86_RS06420	COG0635	Involved in the biosynthesis of porphyrin-containing compound
IMZ86_RS06430	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
IMZ86_RS06435	COG0443	Heat shock 70 kDa protein
IMZ86_RS06440	COG0484	heat shock protein binding
IMZ86_RS06445	COG2264	protein methyltransferase activity
IMZ86_RS06450	COG1385	rRNA (uridine-N3-)-methyltransferase activity
IMZ86_RS06455	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
IMZ86_RS06465	COG1030	water channel activity
IMZ86_RS06470	COG4864	UPF0365 protein
IMZ86_RS06480	COG1702	phosphate starvation-inducible protein PhoH
IMZ86_RS06485	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
IMZ86_RS06490	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
IMZ86_RS06495	COG0295	cytidine deaminase activity
IMZ86_RS06500	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
IMZ86_RS06505	COG1381	Involved in DNA repair and RecF pathway recombination
IMZ86_RS06510	COG0423	glycine-tRNA ligase activity
IMZ86_RS06515	COG0517	IMP dehydrogenase activity
IMZ86_RS06520	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
IMZ86_RS06535	COG2384	SAM-dependent methyltransferase
IMZ86_RS06545	COG0513	Belongs to the DEAD box helicase family
IMZ86_RS06550	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
IMZ86_RS06555	COG1121	(ABC) transporter
IMZ86_RS06560	COG1108	ABC-type Mn2 Zn2 transport systems permease components
IMZ86_RS06570	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
IMZ86_RS06575	COG0768	penicillin binding
IMZ86_RS06580	COG0267	Belongs to the bacterial ribosomal protein bL33 family
IMZ86_RS06585	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
IMZ86_RS06590	COG0457	Tetratricopeptide repeat
IMZ86_RS06590	COG0705	Rhomboid family
IMZ86_RS06595	COG4483	Protein conserved in bacteria
IMZ86_RS06600	COG1940	carbohydrate kinase activity
IMZ86_RS06605	COG0011	TIGRFAM Protein of
IMZ86_RS06610	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IMZ86_RS06615	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
IMZ86_RS06620	COG1459	type II secretion system
IMZ86_RS06625	COG4537	Required for transformation and DNA binding
IMZ86_RS06645	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
IMZ86_RS06650	COG0404	The glycine cleavage system catalyzes the degradation of glycine
IMZ86_RS06655	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
IMZ86_RS06660	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
IMZ86_RS06665	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IMZ86_RS06670	COG0095	Lipoate-protein ligase
IMZ86_RS06685	COG0006	proline dipeptidase activity
IMZ86_RS06690	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
IMZ86_RS06695	COG0511	ligase activity, forming carbon-carbon bonds
IMZ86_RS06700	COG0439	Biotin carboxylase
IMZ86_RS06705	COG1302	Protein conserved in bacteria
IMZ86_RS06710	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
IMZ86_RS06730	COG1438	arginine binding
IMZ86_RS06735	COG0497	DNA recombination
IMZ86_RS06740	COG0280	phosphate acetyltransferase
IMZ86_RS06745	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IMZ86_RS06750	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
IMZ86_RS06755	COG0022	dehydrogenase e1 component
IMZ86_RS06760	COG0508	dehydrogenase complex catalyzes the overall conversion of
IMZ86_RS06770	COG4129	membrane
IMZ86_RS06785	COG2195	Cleaves the N-terminal amino acid of tripeptides
IMZ86_RS06795	COG1609	Transcriptional regulator
IMZ86_RS06800	COG0366	Alpha amylase catalytic
IMZ86_RS06810	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
IMZ86_RS06820	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
IMZ86_RS06825	COG0300	oxidoreductase activity
IMZ86_RS06830	COG0667	Aldo Keto reductase
IMZ86_RS06835	COG0494	nUDIX hydrolase
IMZ86_RS06840	COG0735	belongs to the Fur family
IMZ86_RS06845	COG4974	Belongs to the 'phage' integrase family
IMZ86_RS06855	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
IMZ86_RS06860	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
IMZ86_RS06865	COG1187	pseudouridine synthase activity
IMZ86_RS06870	COG0745	RESPONSE REGULATOR receiver
IMZ86_RS06885	COG1141	Ferredoxin
IMZ86_RS06895	COG0514	ATP-dependent DNA helicase (RecQ)
IMZ86_RS06900	COG1388	LysM domain
IMZ86_RS06905	COG0492	ferredoxin-NADP+ reductase activity
IMZ86_RS06925	COG0539	negative regulation of cytoplasmic translation
IMZ86_RS06935	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
IMZ86_RS06950	COG2226	methyltransferase
IMZ86_RS06955	COG0142	geranyltranstransferase activity
IMZ86_RS06965	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
IMZ86_RS06970	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
IMZ86_RS06995	COG2738	Putative neutral zinc metallopeptidase
IMZ86_RS07000	COG1694	Mazg nucleotide pyrophosphohydrolase
IMZ86_RS07005	COG0438	transferase activity, transferring glycosyl groups
IMZ86_RS07010	COG0617	tRNA 3'-terminal CCA addition
IMZ86_RS07015	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
IMZ86_RS07015	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
IMZ86_RS07020	COG1199	ATP-dependent helicase activity
IMZ86_RS07020	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
IMZ86_RS07025	COG0017	Asparaginyl-tRNA synthetase
IMZ86_RS07030	COG3935	DnaD domain protein
IMZ86_RS07035	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
IMZ86_RS07045	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
IMZ86_RS07045	COG4499	WXG100 protein secretion system (Wss), protein YukC
IMZ86_RS07060	COG4474	Belongs to the UPF0398 family
IMZ86_RS07065	COG3599	regulation of cell shape
IMZ86_RS07075	COG0116	Belongs to the methyltransferase superfamily
IMZ86_RS07085	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
IMZ86_RS07090	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IMZ86_RS07095	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
IMZ86_RS07100	COG0512	Glutamine amidotransferase of anthranilate synthase
IMZ86_RS07105	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
IMZ86_RS07110	COG0134	indole-3-glycerol-phosphate synthase activity
IMZ86_RS07115	COG0135	phosphoribosylanthranilate isomerase activity
IMZ86_RS07130	COG2348	transferase activity, transferring amino-acyl groups
IMZ86_RS07140	COG0561	phosphatase activity
IMZ86_RS07145	COG4607	ABC-type enterochelin transport system periplasmic component
IMZ86_RS07155	COG1164	Oligoendopeptidase f
IMZ86_RS07165	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
IMZ86_RS07170	COG0581	inorganic phosphate transmembrane transporter activity
IMZ86_RS07175	COG0573	inorganic phosphate transmembrane transporter activity
IMZ86_RS07180	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
IMZ86_RS07185	COG2996	Protein conserved in bacteria
IMZ86_RS07190	COG0488	(ABC) transporter
IMZ86_RS07195	COG0527	aspartate kinase activity
IMZ86_RS07200	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
IMZ86_RS07205	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IMZ86_RS07210	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
IMZ86_RS07215	COG2171	N-acyltransferase activity
IMZ86_RS07220	COG1473	amidohydrolase
IMZ86_RS07240	COG1278	Cold shock
IMZ86_RS07250	COG1254	Belongs to the acylphosphatase family
IMZ86_RS07260	COG3853	Toxic anion resistance protein (TelA)
IMZ86_RS07265	COG1114	Component of the transport system for branched-chain amino acids
IMZ86_RS07270	COG4548	von Willebrand factor, type A
IMZ86_RS07275	COG0714	Associated with various cellular activities
IMZ86_RS07295	COG0567	Dehydrogenase, E1 component
IMZ86_RS07300	COG5002	protein histidine kinase activity
IMZ86_RS07305	COG0745	RESPONSE REGULATOR receiver
IMZ86_RS07310	COG0671	phosphoesterase, PA-phosphatase related
IMZ86_RS07315	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
IMZ86_RS07325	COG0793	Belongs to the peptidase S41A family
IMZ86_RS07330	COG4479	Belongs to the UPF0346 family
IMZ86_RS07340	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IMZ86_RS07370	COG1413	lyase activity
IMZ86_RS07380	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
IMZ86_RS07385	COG0328	RNA-DNA hybrid ribonuclease activity
IMZ86_RS07405	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
IMZ86_RS07415	COG3623	hexulose-6-phosphate isomerase
IMZ86_RS07435	COG0287	Prephenate dehydrogenase
IMZ86_RS07440	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IMZ86_RS07445	COG1942	4-Oxalocrotonate Tautomerase
IMZ86_RS07475	COG0392	lysyltransferase activity
IMZ86_RS07475	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
IMZ86_RS07480	COG0628	permease
IMZ86_RS07485	COG1115	amino acid carrier protein
IMZ86_RS07490	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IMZ86_RS07495	COG0187	DNA topoisomerase II activity
IMZ86_RS07500	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
IMZ86_RS07505	COG4841	protein insertion into membrane
IMZ86_RS07515	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
IMZ86_RS07520	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
IMZ86_RS07525	COG1970	mechanosensitive ion channel activity
IMZ86_RS07530	COG0419	ATPase involved in DNA repair
IMZ86_RS07540	COG4846	Membrane protein involved in cytochrome C biogenesis
IMZ86_RS07545	COG3763	UPF0154 protein
IMZ86_RS07550	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
IMZ86_RS07555	COG4224	UPF0291 protein
IMZ86_RS07565	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
IMZ86_RS07570	COG2340	Cysteine-rich secretory protein family
IMZ86_RS07580	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
IMZ86_RS07595	COG0833	amino acid
IMZ86_RS07605	COG0561	phosphatase activity
IMZ86_RS07610	COG0083	homoserine kinase activity
IMZ86_RS07615	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
IMZ86_RS07620	COG0460	homoserine dehydrogenase
IMZ86_RS07640	COG1525	nuclease
IMZ86_RS07655	COG2197	response regulator
IMZ86_RS07660	COG4585	Histidine kinase
IMZ86_RS07660	COG2203	Gaf domain
IMZ86_RS07670	COG1131	(ABC) transporter
IMZ86_RS07675	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IMZ86_RS07690	COG0789	Transcriptional regulator
IMZ86_RS07695	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
IMZ86_RS07700	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
IMZ86_RS07710	COG1923	regulation of RNA biosynthetic process
IMZ86_RS07715	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
IMZ86_RS07725	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
IMZ86_RS07730	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
IMZ86_RS07735	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
IMZ86_RS07745	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
IMZ86_RS07750	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
IMZ86_RS07765	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
IMZ86_RS07775	COG4195	phage-related replication protein
IMZ86_RS07780	COG1013	pyruvate-flavodoxin oxidoreductase activity
IMZ86_RS07785	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
IMZ86_RS07785	COG0674	pyruvate-flavodoxin oxidoreductase activity
IMZ86_RS07790	COG1692	metallophosphoesterase
IMZ86_RS07800	COG1418	mRNA catabolic process
IMZ86_RS07805	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
IMZ86_RS07810	COG1058	Belongs to the CinA family
IMZ86_RS07810	COG1546	Belongs to the CinA family
IMZ86_RS07830	COG0300	oxidoreductase activity
IMZ86_RS07835	COG0612	Peptidase, M16
IMZ86_RS07840	COG0612	Peptidase, M16
IMZ86_RS07845	COG2188	Transcriptional regulator
IMZ86_RS07850	COG1674	ftsk spoiiie
IMZ86_RS07855	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
IMZ86_RS07860	COG1185	polyribonucleotide nucleotidyltransferase activity
IMZ86_RS07870	COG0196	riboflavin kinase activity
IMZ86_RS07880	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
IMZ86_RS07885	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
IMZ86_RS07890	COG1358	cellular component organization or biogenesis
IMZ86_RS07895	COG2740	Nucleic-acid-binding protein implicated in transcription termination
IMZ86_RS07900	COG0195	Participates in both transcription termination and antitermination
IMZ86_RS07905	COG0779	Required for maturation of 30S ribosomal subunits
IMZ86_RS07910	COG2176	DNA-directed DNA polymerase activity
IMZ86_RS07915	COG0442	prolyl-tRNA aminoacylation
IMZ86_RS07930	COG4589	Belongs to the CDS family
IMZ86_RS07935	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
IMZ86_RS07940	COG0233	cytoplasmic translational termination
IMZ86_RS07945	COG0528	UMP kinase activity
IMZ86_RS07950	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
IMZ86_RS07955	COG0052	Belongs to the universal ribosomal protein uS2 family
IMZ86_RS07960	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
IMZ86_RS07965	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
IMZ86_RS07970	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
IMZ86_RS07975	COG4974	Belongs to the 'phage' integrase family
IMZ86_RS07980	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
IMZ86_RS07985	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
IMZ86_RS07990	COG0758	DNA mediated transformation
IMZ86_RS07995	COG2348	transferase activity, transferring amino-acyl groups
IMZ86_RS08000	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
IMZ86_RS08005	COG0045	succinate-CoA ligase (ADP-forming) activity
IMZ86_RS08010	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IMZ86_RS08020	COG4485	Bacterial membrane protein, YfhO
IMZ86_RS08030	COG0335	large ribosomal subunit rRNA binding
IMZ86_RS08035	COG0336	Belongs to the RNA methyltransferase TrmD family
IMZ86_RS08040	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
IMZ86_RS08045	COG0228	four-way junction DNA binding
IMZ86_RS08060	COG0183	Belongs to the thiolase family
IMZ86_RS08065	COG0318	PFAM AMP-dependent synthetase and ligase
IMZ86_RS08075	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
IMZ86_RS08080	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
IMZ86_RS08085	COG0552	protein localization to endoplasmic reticulum
IMZ86_RS08090	COG1196	nuclear chromosome segregation
IMZ86_RS08095	COG0571	ribonuclease III activity
IMZ86_RS08100	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IMZ86_RS08115	COG0416	fatty acid biosynthetic process
IMZ86_RS08120	COG1349	DNA-binding transcription factor activity
IMZ86_RS08125	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
IMZ86_RS08130	COG1461	Dihydroxyacetone kinase
IMZ86_RS08135	COG1302	Protein conserved in bacteria
IMZ86_RS08140	COG0227	Belongs to the bacterial ribosomal protein bL28 family
IMZ86_RS08150	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
IMZ86_RS08165	COG0631	protein serine/threonine phosphatase activity
IMZ86_RS08175	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
IMZ86_RS08175	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
IMZ86_RS08180	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
IMZ86_RS08190	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
IMZ86_RS08195	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
IMZ86_RS08200	COG1758	RNA polymerase activity
IMZ86_RS08205	COG0194	GDP metabolic process
IMZ86_RS08225	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
IMZ86_RS08230	COG0284	orotidine-5'-phosphate decarboxylase activity
IMZ86_RS08240	COG0505	Belongs to the CarA family
IMZ86_RS08250	COG0540	Belongs to the ATCase OTCase family
IMZ86_RS08255	COG2233	PERMEase
IMZ86_RS08260	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
IMZ86_RS08265	COG0564	pseudouridine synthase activity
IMZ86_RS08270	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
IMZ86_RS08280	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
IMZ86_RS08285	COG3599	regulation of cell shape
IMZ86_RS08290	COG2302	S4 RNA-binding domain
IMZ86_RS08295	COG0762	integral membrane protein
IMZ86_RS08300	COG1799	cell septum assembly
IMZ86_RS08305	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
IMZ86_RS08310	COG1496	oxidoreductase activity
IMZ86_RS08315	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
IMZ86_RS08320	COG0849	cell division
IMZ86_RS08325	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
IMZ86_RS08330	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
IMZ86_RS08335	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
IMZ86_RS08340	COG0768	penicillin binding
IMZ86_RS08345	COG4839	cell division protein FtsL
IMZ86_RS08350	COG0275	rRNA processing
IMZ86_RS08360	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
IMZ86_RS08365	COG0454	-acetyltransferase
IMZ86_RS08375	COG1011	Hydrolase
IMZ86_RS08385	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
IMZ86_RS08390	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
IMZ86_RS08395	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
IMZ86_RS08400	COG1053	succinate dehydrogenase
IMZ86_RS08405	COG2009	succinate dehydrogenase
IMZ86_RS08410	COG0322	excinuclease ABC activity
IMZ86_RS08415	COG3118	belongs to the thioredoxin family
IMZ86_RS08420	COG1193	negative regulation of DNA recombination
IMZ86_RS08425	COG1796	DNA polymerase
IMZ86_RS08425	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
IMZ86_RS08435	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
IMZ86_RS08440	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IMZ86_RS08445	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IMZ86_RS08445	COG0072	phenylalanine-tRNA ligase activity
IMZ86_RS08450	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
IMZ86_RS08455	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IMZ86_RS08460	COG0333	Belongs to the bacterial ribosomal protein bL32 family
IMZ86_RS08470	COG1323	Belongs to the UPF0348 family
IMZ86_RS08475	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
IMZ86_RS08480	COG0742	ribosomal rna small subunit methyltransferase
IMZ86_RS08500	COG3679	Belongs to the UPF0342 family
IMZ86_RS08515	COG0109	protoheme IX farnesyltransferase activity
IMZ86_RS08520	COG1612	heme a metabolic process
IMZ86_RS08530	COG0772	Belongs to the SEDS family
IMZ86_RS08535	COG4838	Belongs to the UPF0358 family
IMZ86_RS08540	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
IMZ86_RS08550	COG1217	gtp-binding protein TYPA
IMZ86_RS08560	COG0483	inositol monophosphate 1-phosphatase activity
IMZ86_RS08565	COG4493	Belongs to the UPF0637 family
IMZ86_RS08585	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
IMZ86_RS08590	COG1177	transmembrane transport
IMZ86_RS08610	COG4476	Belongs to the UPF0223 family
IMZ86_RS08625	COG0022	dehydrogenase e1 component
IMZ86_RS08640	COG0242	peptide deformylase activity
IMZ86_RS08645	COG5503	Protein of unknown function (DUF1447)
IMZ86_RS08650	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
IMZ86_RS08660	COG0569	domain protein
IMZ86_RS08675	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IMZ86_RS08690	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
IMZ86_RS08705	COG4172	Belongs to the ABC transporter superfamily
IMZ86_RS08710	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
IMZ86_RS08715	COG0151	Belongs to the GarS family
IMZ86_RS08720	COG0138	bifunctional purine biosynthesis protein purh
IMZ86_RS08730	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
IMZ86_RS08740	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IMZ86_RS08745	COG0047	phosphoribosylformylglycinamidine synthase activity
IMZ86_RS08750	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IMZ86_RS08755	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
IMZ86_RS08760	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
IMZ86_RS08765	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
IMZ86_RS08770	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
IMZ86_RS08775	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IMZ86_RS08775	COG1017	nitric oxide dioxygenase activity
IMZ86_RS08785	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
IMZ86_RS08795	COG1845	cytochrome c oxidase, subunit III
IMZ86_RS08800	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
IMZ86_RS08810	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
IMZ86_RS08815	COG1316	TRANSCRIPTIONal
IMZ86_RS08840	COG3594	Acyltransferase
IMZ86_RS08845	COG0436	Aminotransferase
IMZ86_RS08850	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
IMZ86_RS08855	COG0596	Alpha beta hydrolase
IMZ86_RS08860	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
IMZ86_RS08865	COG1169	isochorismate synthase
IMZ86_RS08870	COG1575	Belongs to the MenA family. Type 1 subfamily
IMZ86_RS08940	COG4873	Protein conserved in bacteria
IMZ86_RS08950	COG0737	Belongs to the 5'-nucleotidase family
IMZ86_RS08955	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
IMZ86_RS08960	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IMZ86_RS08965	COG0861	Integral membrane protein TerC family
IMZ86_RS08980	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
IMZ86_RS08985	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
IMZ86_RS08990	COG2814	Major facilitator Superfamily
IMZ86_RS08995	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
IMZ86_RS09000	COG0789	Transcriptional regulator
IMZ86_RS09005	COG4221	oxidoreductase activity
IMZ86_RS09015	COG0628	permease
IMZ86_RS09025	COG0475	glutathione-regulated potassium exporter activity
IMZ86_RS09025	COG0569	domain protein
IMZ86_RS09030	COG2239	Acts as a magnesium transporter
IMZ86_RS09035	COG0564	pseudouridine synthase activity
IMZ86_RS09045	COG2357	RelA SpoT domain protein
IMZ86_RS09060	COG2346	COG2346, Truncated hemoglobins
IMZ86_RS09065	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
IMZ86_RS09070	COG1164	Oligoendopeptidase f
IMZ86_RS09085	COG1393	Belongs to the ArsC family
IMZ86_RS09090	COG0180	Tryptophanyl-tRNA synthetase
IMZ86_RS09095	COG2226	methyltransferase
IMZ86_RS09100	COG4166	transmembrane transport
IMZ86_RS09105	COG4608	Belongs to the ABC transporter superfamily
IMZ86_RS09110	COG0444	Belongs to the ABC transporter superfamily
IMZ86_RS09115	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IMZ86_RS09120	COG0601	transmembrane transport
IMZ86_RS09135	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IMZ86_RS09145	COG0542	response to heat
IMZ86_RS09155	COG0561	phosphatase activity
IMZ86_RS09160	COG0446	pyridine nucleotide-disulphide oxidoreductase
IMZ86_RS09175	COG1074	ATP-dependent DNA helicase activity
IMZ86_RS09195	COG0398	Pfam SNARE associated Golgi protein
IMZ86_RS09200	COG0166	Belongs to the GPI family
IMZ86_RS09205	COG0137	argininosuccinate synthase activity
IMZ86_RS09235	COG1902	pentaerythritol trinitrate reductase activity
IMZ86_RS09240	COG1098	S1 RNA binding domain
IMZ86_RS09245	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
IMZ86_RS09255	COG2111	Na H antiporter
IMZ86_RS09255	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
IMZ86_RS09260	COG2111	Na H antiporter
IMZ86_RS09265	COG1006	Multisubunit Na H antiporter MnhC subunit
IMZ86_RS09270	COG0651	ATP synthesis coupled electron transport
IMZ86_RS09275	COG1863	multisubunit Na H antiporter MnhE subunit
IMZ86_RS09280	COG2212	antiporter activity
IMZ86_RS09285	COG1320	monovalent cation:proton antiporter activity
IMZ86_RS09295	COG2050	protein possibly involved in aromatic compounds catabolism
IMZ86_RS09300	COG2056	Na+-H+ antiporter family
IMZ86_RS09305	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
IMZ86_RS09310	COG1252	NADH dehydrogenase
IMZ86_RS09320	COG1132	(ABC) transporter
IMZ86_RS09330	COG1129	ABC transporter
IMZ86_RS09360	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IMZ86_RS09360	COG2226	methyltransferase
IMZ86_RS09360	COG3433	isochorismatase activity
IMZ86_RS09365	COG1021	2,3-dihydroxybenzoate-AMP ligase
IMZ86_RS09380	COG0316	Belongs to the HesB IscA family
IMZ86_RS09385	COG4844	belongs to the
IMZ86_RS09390	COG1252	NADH dehydrogenase
IMZ86_RS09395	COG4837	Protein of unknown function (DUF1462)
IMZ86_RS09400	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
IMZ86_RS09405	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
IMZ86_RS09410	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IMZ86_RS09415	COG1696	Membrane protein involved in D-alanine export
IMZ86_RS09420	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IMZ86_RS09430	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IMZ86_RS09435	COG0647	UMP catabolic process
IMZ86_RS09440	COG2445	Protein of unknown function DUF86
IMZ86_RS09450	COG4470	Protein conserved in bacteria
IMZ86_RS09455	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
IMZ86_RS09460	COG0737	Belongs to the 5'-nucleotidase family
IMZ86_RS09465	COG0730	response to heat
IMZ86_RS09470	COG1801	Protein of unknown function DUF72
IMZ86_RS09475	COG2070	2-Nitropropane dioxygenase
IMZ86_RS09480	COG1253	flavin adenine dinucleotide binding
IMZ86_RS09630	COG3942	CHAP domain
IMZ86_RS09630	COG1388	LysM domain
IMZ86_RS09655	COG0719	Fe-S assembly protein
IMZ86_RS09660	COG0822	iron-sulfur transferase activity
IMZ86_RS09670	COG0719	Fe-S assembly protein
IMZ86_RS09675	COG0396	ATPase activity
IMZ86_RS09695	COG1464	Belongs to the NlpA lipoprotein family
IMZ86_RS09700	COG2011	ABC-type metal ion transport system permease component
IMZ86_RS09705	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
IMZ86_RS09715	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
IMZ86_RS09720	COG0509	glycine decarboxylation via glycine cleavage system
IMZ86_RS09725	COG1393	Belongs to the ArsC family
IMZ86_RS09730	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
IMZ86_RS09740	COG0710	3-dehydroquinate dehydratase activity
IMZ86_RS09745	COG1764	response to oxidative stress
IMZ86_RS09755	COG0588	phosphoglycerate mutase activity
IMZ86_RS09785	COG4195	phage-related replication protein
IMZ86_RS09800	COG2259	Doxx family
IMZ86_RS09805	COG0346	lactoylglutathione lyase activity
IMZ86_RS09815	COG1611	Belongs to the LOG family
IMZ86_RS09905	COG0557	exoribonuclease II activity
IMZ86_RS09910	COG1647	Serine aminopeptidase, S33
IMZ86_RS09915	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
IMZ86_RS09925	COG0148	phosphopyruvate hydratase activity
IMZ86_RS09930	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
IMZ86_RS09935	COG0149	triose-phosphate isomerase activity
IMZ86_RS09940	COG0126	phosphoglycerate kinase activity
IMZ86_RS09960	COG1090	epimerase
IMZ86_RS09965	COG0740	serine-type endopeptidase activity
IMZ86_RS09970	COG1481	regulation of sporulation
IMZ86_RS09975	COG0391	Required for morphogenesis under gluconeogenic growth conditions
IMZ86_RS09980	COG1660	Displays ATPase and GTPase activities
IMZ86_RS09985	COG0492	ferredoxin-NADP+ reductase activity
IMZ86_RS10000	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
IMZ86_RS10005	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
IMZ86_RS10010	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
IMZ86_RS10030	COG1388	LysM domain
IMZ86_RS10030	COG3942	CHAP domain
IMZ86_RS10040	COG0653	protein targeting
IMZ86_RS10050	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
IMZ86_RS10055	COG1040	competence protein
IMZ86_RS10060	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
IMZ86_RS10070	COG1739	Uncharacterized protein family UPF0029
IMZ86_RS10075	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
IMZ86_RS10080	COG2199	diguanylate cyclase activity
IMZ86_RS10095	COG2195	Cleaves the N-terminal amino acid of tripeptides
IMZ86_RS10100	COG1929	Belongs to the glycerate kinase type-1 family
IMZ86_RS10120	COG0812	UDP-N-acetylmuramate dehydrogenase activity
IMZ86_RS10130	COG4607	ABC-type enterochelin transport system periplasmic component
IMZ86_RS10135	COG4604	ABC transporter, ATP-binding protein
IMZ86_RS10140	COG4605	iron ion homeostasis
IMZ86_RS10145	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IMZ86_RS10150	COG4607	ABC-type enterochelin transport system periplasmic component
IMZ86_RS10155	COG4604	ABC transporter, ATP-binding protein
IMZ86_RS10160	COG4605	iron ion homeostasis
IMZ86_RS10165	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IMZ86_RS10170	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IMZ86_RS10175	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IMZ86_RS10180	COG1780	Probably involved in ribonucleotide reductase function
IMZ86_RS10190	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
IMZ86_RS10195	COG3104	oligopeptide transport
IMZ86_RS10200	COG1597	lipid kinase activity
IMZ86_RS10210	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
IMZ86_RS10215	COG3104	oligopeptide transport
IMZ86_RS10220	COG1174	glycine betaine transport
IMZ86_RS10230	COG0514	ATP-dependent DNA helicase (RecQ)
IMZ86_RS10235	COG0488	(ABC) transporter
IMZ86_RS10250	COG1368	sulfuric ester hydrolase activity
IMZ86_RS10260	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
IMZ86_RS10270	COG0512	Glutamine amidotransferase of anthranilate synthase
IMZ86_RS10270	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
IMZ86_RS10275	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
IMZ86_RS10275	COG0512	Glutamine amidotransferase of anthranilate synthase
IMZ86_RS10285	COG0720	synthase
IMZ86_RS10300	COG0463	Glycosyl transferase, family 2
IMZ86_RS10305	COG0656	L-ascorbic acid biosynthetic process
IMZ86_RS10310	COG1253	flavin adenine dinucleotide binding
IMZ86_RS10315	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IMZ86_RS10315	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IMZ86_RS10315	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
IMZ86_RS10320	COG1105	Belongs to the carbohydrate kinase PfkB family
IMZ86_RS10325	COG1349	DNA-binding transcription factor activity
IMZ86_RS10330	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
IMZ86_RS10350	COG0415	Belongs to the DNA photolyase family
IMZ86_RS10355	COG0471	metal ion transport
IMZ86_RS10360	COG0039	L-malate dehydrogenase activity
IMZ86_RS10375	COG0523	cobalamin synthesis protein
IMZ86_RS10385	COG1968	undecaprenyl-diphosphatase activity
IMZ86_RS10395	COG1671	Belongs to the UPF0178 family
IMZ86_RS10400	COG1611	Belongs to the LOG family
IMZ86_RS10425	COG2839	Protein conserved in bacteria
IMZ86_RS10430	COG2814	Major facilitator Superfamily
IMZ86_RS10435	COG0583	DNA-binding transcription factor activity
IMZ86_RS10450	COG0217	transcriptional regulatory protein
IMZ86_RS10470	COG1388	LysM domain
IMZ86_RS10470	COG3942	CHAP domain
IMZ86_RS10475	COG0306	phosphate transporter
IMZ86_RS10480	COG1392	Phosphate transport regulator
IMZ86_RS10485	COG0577	efflux transmembrane transporter activity
IMZ86_RS10490	COG1136	(ABC) transporter
IMZ86_RS10495	COG2205	protein histidine kinase activity
IMZ86_RS10500	COG0745	RESPONSE REGULATOR receiver
IMZ86_RS10505	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
IMZ86_RS10515	COG0657	acetylesterase activity
IMZ86_RS10520	COG3949	Membrane
IMZ86_RS10530	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
IMZ86_RS10535	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IMZ86_RS10540	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IMZ86_RS10545	COG1120	ATPase activity
IMZ86_RS10550	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
IMZ86_RS10560	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
IMZ86_RS10565	COG0463	Glycosyl transferase, family 2
IMZ86_RS10565	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
IMZ86_RS10570	COG0438	transferase activity, transferring glycosyl groups
IMZ86_RS10575	COG1132	(ABC) transporter
IMZ86_RS10580	COG1686	Belongs to the peptidase S11 family
IMZ86_RS10585	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
IMZ86_RS10590	COG1215	transferase activity, transferring glycosyl groups
IMZ86_RS10595	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
IMZ86_RS10600	COG1682	transport, permease protein
IMZ86_RS10605	COG1134	teichoic acid transport
IMZ86_RS10620	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
IMZ86_RS10630	COG1321	iron dependent repressor
IMZ86_RS10635	COG1121	(ABC) transporter
IMZ86_RS10640	COG1108	ABC-type Mn2 Zn2 transport systems permease components
IMZ86_RS10645	COG0803	Belongs to the bacterial solute-binding protein 9 family
IMZ86_RS10655	COG1320	monovalent cation:proton antiporter activity
IMZ86_RS10660	COG2212	antiporter activity
IMZ86_RS10665	COG1863	multisubunit Na H antiporter MnhE subunit
IMZ86_RS10670	COG0651	ATP synthesis coupled electron transport
IMZ86_RS10675	COG1006	Multisubunit Na H antiporter MnhC subunit
IMZ86_RS10680	COG2111	Na H antiporter
IMZ86_RS10685	COG2111	Na H antiporter
IMZ86_RS10685	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
IMZ86_RS10690	COG4974	Belongs to the 'phage' integrase family
IMZ86_RS10720	COG0596	Alpha beta hydrolase
IMZ86_RS10745	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IMZ86_RS10750	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
IMZ86_RS10770	COG0018	arginyl-trna synthetase
IMZ86_RS10795	COG1064	alcohol dehydrogenase
IMZ86_RS10805	COG1078	dGTPase activity
IMZ86_RS10815	COG0655	NAD(P)H dehydrogenase (quinone) activity
IMZ86_RS10820	COG0667	Aldo Keto reductase
IMZ86_RS10830	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IMZ86_RS10835	COG4844	belongs to the
IMZ86_RS10855	COG0095	Lipoate-protein ligase
IMZ86_RS10865	COG3253	May function as heme-dependent peroxidase
IMZ86_RS10890	COG0531	amino acid
IMZ86_RS10895	COG2363	Small membrane protein
IMZ86_RS10905	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
IMZ86_RS10940	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
IMZ86_RS10945	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
IMZ86_RS10955	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
IMZ86_RS10965	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
IMZ86_RS10990	COG0561	phosphatase activity
IMZ86_RS11000	COG1428	Deoxynucleoside kinase
IMZ86_RS11005	COG1428	Deoxynucleoside kinase
IMZ86_RS11025	COG0531	amino acid
IMZ86_RS11030	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
IMZ86_RS11040	COG1279	arginine transmembrane transporter activity
IMZ86_RS11065	COG1473	amidohydrolase
IMZ86_RS11070	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
IMZ86_RS11085	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
IMZ86_RS11095	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IMZ86_RS11100	COG0085	RNA polymerase activity
IMZ86_RS11105	COG2813	Specifically methylates the guanine in position
IMZ86_RS11110	COG0222	ribosome binding
IMZ86_RS11115	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
IMZ86_RS11120	COG0081	regulation of translation
IMZ86_RS11130	COG0250	Participates in transcription elongation, termination and antitermination
IMZ86_RS11135	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
IMZ86_RS11140	COG0267	Belongs to the bacterial ribosomal protein bL33 family
IMZ86_RS11150	COG3688	RNA-binding protein containing a PIN domain
IMZ86_RS11155	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IMZ86_RS11160	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
IMZ86_RS11165	COG0215	cysteine-tRNA ligase activity
IMZ86_RS11170	COG1045	serine acetyltransferase
IMZ86_RS11175	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
IMZ86_RS11180	COG4956	integral membrane protein (PIN domain superfamily)
IMZ86_RS11185	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
IMZ86_RS11190	COG0542	response to heat
IMZ86_RS11195	COG3869	Catalyzes the specific phosphorylation of arginine residues in
IMZ86_RS11200	COG3880	PFAM UvrB UvrC protein
IMZ86_RS11205	COG4463	regulation of RNA biosynthetic process
IMZ86_RS11210	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
IMZ86_RS11215	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
IMZ86_RS11220	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
IMZ86_RS11225	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IMZ86_RS11310	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
IMZ86_RS11315	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
IMZ86_RS11320	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
IMZ86_RS11330	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
IMZ86_RS11340	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IMZ86_RS11355	COG1098	S1 RNA binding domain
IMZ86_RS11365	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
IMZ86_RS11370	COG3956	TIGRFAM MazG family protein
IMZ86_RS11375	COG2244	polysaccharide biosynthetic process
IMZ86_RS11380	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
IMZ86_RS11385	COG0193	aminoacyl-tRNA hydrolase activity
IMZ86_RS11395	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IMZ86_RS11400	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
IMZ86_RS11410	COG0251	oxidation-reduction process
IMZ86_RS11415	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
IMZ86_RS11420	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
IMZ86_RS11425	COG4466	Protein conserved in bacteria
IMZ86_RS11430	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
IMZ86_RS11435	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
IMZ86_RS11440	COG0084	hydrolase, TatD family'
IMZ86_RS11445	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IMZ86_RS11445	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IMZ86_RS11450	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
IMZ86_RS11460	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
IMZ86_RS11470	COG1774	PSP1 C-terminal conserved region
IMZ86_RS11475	COG0470	DNA polymerase III
IMZ86_RS11480	COG3870	Protein conserved in bacteria
IMZ86_RS11485	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
IMZ86_RS11490	COG1982	Orn Lys Arg decarboxylase major
IMZ86_RS11525	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
IMZ86_RS11535	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
IMZ86_RS11550	COG2188	Transcriptional regulator
IMZ86_RS11555	COG0366	Alpha amylase catalytic
IMZ86_RS11560	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IMZ86_RS11560	COG1263	PTS System
IMZ86_RS11570	COG0493	'glutamate synthase
IMZ86_RS11575	COG0070	glutamate synthase
IMZ86_RS11575	COG0069	glutamate synthase activity
IMZ86_RS11575	COG0067	glutamate synthase
IMZ86_RS11580	COG0583	DNA-binding transcription factor activity
IMZ86_RS11610	COG1464	Belongs to the NlpA lipoprotein family
IMZ86_RS11615	COG2011	ABC-type metal ion transport system permease component
IMZ86_RS11620	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
IMZ86_RS11625	COG1132	(ABC) transporter
IMZ86_RS11630	COG1132	(ABC) transporter
IMZ86_RS11630	COG2375	cellular response to nickel ion
IMZ86_RS11635	COG0626	cystathionine gamma-synthase activity
IMZ86_RS11640	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
IMZ86_RS11650	COG0733	neurotransmitter:sodium symporter activity
IMZ86_RS11670	COG5609	conserved protein (DUF2294)
IMZ86_RS11675	COG3002	Belongs to the UPF0753 family
IMZ86_RS11680	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
IMZ86_RS11685	COG0523	cobalamin synthesis protein
IMZ86_RS11705	COG0519	Catalyzes the synthesis of GMP from XMP
IMZ86_RS11705	COG0518	GMP synthase (glutamine-hydrolyzing) activity
IMZ86_RS11710	COG0517	IMP dehydrogenase activity
IMZ86_RS11710	COG0516	GMP reductase activity
IMZ86_RS11715	COG2233	PERMEase
IMZ86_RS11720	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
IMZ86_RS11740	COG1823	symporter activity
IMZ86_RS11745	COG0778	Nitroreductase
IMZ86_RS11755	COG0450	alkyl hydroperoxide reductase
IMZ86_RS11760	COG3634	alkyl hydroperoxide reductase activity
IMZ86_RS11770	COG0588	phosphoglycerate mutase activity
IMZ86_RS11810	COG3728	DNA packaging
IMZ86_RS11810	COG5484	DNA packaging
IMZ86_RS11885	COG0582	viral genome integration into host DNA
IMZ86_RS11890	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
IMZ86_RS11900	COG0360	Binds together with S18 to 16S ribosomal RNA
IMZ86_RS11915	COG0012	GTP binding
IMZ86_RS11920	COG4481	Protein conserved in bacteria
IMZ86_RS11925	COG0668	transmembrane transport
IMZ86_RS11930	COG1475	DNA binding
IMZ86_RS11935	COG0626	cystathionine gamma-synthase activity
IMZ86_RS11940	COG0626	cystathionine gamma-synthase activity
IMZ86_RS11945	COG0646	methionine synthase
IMZ86_RS11945	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
IMZ86_RS11950	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
IMZ86_RS11975	COG0577	efflux transmembrane transporter activity
IMZ86_RS11980	COG1136	(ABC) transporter
IMZ86_RS12000	COG2205	protein histidine kinase activity
IMZ86_RS12015	COG0745	RESPONSE REGULATOR receiver
IMZ86_RS12040	COG3878	Protein conserved in bacteria
IMZ86_RS12045	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IMZ86_RS12050	COG2271	Major facilitator Superfamily
IMZ86_RS12065	COG1136	(ABC) transporter
IMZ86_RS12070	COG0577	efflux transmembrane transporter activity
IMZ86_RS12080	COG1396	sequence-specific DNA binding
IMZ86_RS12090	COG1028	Short-chain dehydrogenase reductase Sdr
IMZ86_RS12105	COG1063	alcohol dehydrogenase
IMZ86_RS12125	COG1475	DNA binding
IMZ86_RS12135	COG0445	tRNA wobble uridine modification
IMZ86_RS12140	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
IMZ86_RS12145	COG0594	ribonuclease P activity