locus-tag	class	description
C7J88_RS00005	COG0861	Integral membrane protein TerC family
C7J88_RS00010	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C7J88_RS00015	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
C7J88_RS00020	COG0737	Belongs to the 5'-nucleotidase family
C7J88_RS00065	COG4873	Protein conserved in bacteria
C7J88_RS00085	COG4619	ABC transporter
C7J88_RS00090	COG0390	transport system, permease component
C7J88_RS00095	COG1575	Belongs to the MenA family. Type 1 subfamily
C7J88_RS00105	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
C7J88_RS00110	COG0596	Alpha beta hydrolase
C7J88_RS00115	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
C7J88_RS00120	COG0436	Aminotransferase
C7J88_RS00125	COG3594	Acyltransferase
C7J88_RS00150	COG1316	TRANSCRIPTIONal
C7J88_RS00165	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
C7J88_RS00165	COG1017	nitric oxide dioxygenase activity
C7J88_RS00175	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
C7J88_RS00185	COG1845	cytochrome c oxidase, subunit III
C7J88_RS00190	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
C7J88_RS00195	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
C7J88_RS00200	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
C7J88_RS00205	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
C7J88_RS00210	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
C7J88_RS00215	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
C7J88_RS00225	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
C7J88_RS00230	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
C7J88_RS00235	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
C7J88_RS00245	COG0138	bifunctional purine biosynthesis protein purh
C7J88_RS00260	COG1122	ATPase activity
C7J88_RS00275	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
C7J88_RS00285	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
C7J88_RS00300	COG0569	domain protein
C7J88_RS00305	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
C7J88_RS00310	COG5503	Protein of unknown function (DUF1447)
C7J88_RS00315	COG0242	peptide deformylase activity
C7J88_RS00345	COG4476	Belongs to the UPF0223 family
C7J88_RS00355	COG3842	ATPase activity
C7J88_RS00360	COG1177	transmembrane transport
C7J88_RS00365	COG1177	transmembrane transport
C7J88_RS00370	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
C7J88_RS00385	COG4493	Belongs to the UPF0637 family
C7J88_RS00390	COG0483	inositol monophosphate 1-phosphatase activity
C7J88_RS00400	COG1217	gtp-binding protein TYPA
C7J88_RS00405	COG1902	pentaerythritol trinitrate reductase activity
C7J88_RS00415	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
C7J88_RS00420	COG4838	Belongs to the UPF0358 family
C7J88_RS00425	COG0772	Belongs to the SEDS family
C7J88_RS00435	COG1612	heme a metabolic process
C7J88_RS00440	COG0109	protoheme IX farnesyltransferase activity
C7J88_RS00455	COG3679	Belongs to the UPF0342 family
C7J88_RS00465	COG4471	UPF0298 protein
C7J88_RS00475	COG0742	ribosomal rna small subunit methyltransferase
C7J88_RS00480	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
C7J88_RS00485	COG1323	Belongs to the UPF0348 family
C7J88_RS00500	COG0333	Belongs to the bacterial ribosomal protein bL32 family
C7J88_RS00505	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
C7J88_RS00510	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
C7J88_RS00515	COG0072	phenylalanine-tRNA ligase activity
C7J88_RS00520	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
C7J88_RS00525	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
C7J88_RS00535	COG1796	DNA polymerase
C7J88_RS00535	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
C7J88_RS00550	COG0322	excinuclease ABC activity
C7J88_RS00555	COG2009	succinate dehydrogenase
C7J88_RS00560	COG1053	succinate dehydrogenase
C7J88_RS00565	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
C7J88_RS00630	COG0454	-acetyltransferase
C7J88_RS00635	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
C7J88_RS00640	COG2001	Belongs to the MraZ family
C7J88_RS00645	COG0275	rRNA processing
C7J88_RS00650	COG4839	cell division protein FtsL
C7J88_RS00655	COG0768	penicillin binding
C7J88_RS00665	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
C7J88_RS00675	COG0849	cell division
C7J88_RS00680	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
C7J88_RS00690	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
C7J88_RS00695	COG1799	cell septum assembly
C7J88_RS00700	COG0762	integral membrane protein
C7J88_RS00705	COG2302	S4 RNA-binding domain
C7J88_RS00710	COG3599	regulation of cell shape
C7J88_RS00740	COG1136	(ABC) transporter
C7J88_RS00750	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
C7J88_RS00755	COG0564	pseudouridine synthase activity
C7J88_RS00760	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
C7J88_RS00765	COG2233	PERMEase
C7J88_RS00770	COG0540	Belongs to the ATCase OTCase family
C7J88_RS00780	COG0505	Belongs to the CarA family
C7J88_RS00785	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
C7J88_RS00795	COG0167	dihydroorotate dehydrogenase activity
C7J88_RS00800	COG0284	orotidine-5'-phosphate decarboxylase activity
C7J88_RS00805	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
C7J88_RS00810	COG1846	Transcriptional regulator
C7J88_RS00825	COG1293	RNA-binding protein homologous to eukaryotic snRNP
C7J88_RS00830	COG0194	GDP metabolic process
C7J88_RS00835	COG1758	RNA polymerase activity
C7J88_RS00840	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
C7J88_RS00845	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
C7J88_RS00900	COG0242	peptide deformylase activity
C7J88_RS00905	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
C7J88_RS00910	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
C7J88_RS00910	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
C7J88_RS00915	COG0820	rRNA (adenine-C2-)-methyltransferase activity
C7J88_RS00920	COG0631	protein serine/threonine phosphatase activity
C7J88_RS00935	COG1162	GTPase activity
C7J88_RS00940	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
C7J88_RS00955	COG1302	Protein conserved in bacteria
C7J88_RS00965	COG1760	l-serine dehydratase
C7J88_RS00970	COG1760	l-serine dehydratase
C7J88_RS00975	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
C7J88_RS00980	COG1349	DNA-binding transcription factor activity
C7J88_RS00985	COG0416	fatty acid biosynthetic process
C7J88_RS01000	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C7J88_RS01010	COG1196	nuclear chromosome segregation
C7J88_RS01015	COG0552	protein localization to endoplasmic reticulum
C7J88_RS01020	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
C7J88_RS01025	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
C7J88_RS01030	COG0228	four-way junction DNA binding
C7J88_RS01040	COG0336	Belongs to the RNA methyltransferase TrmD family
C7J88_RS01060	COG1136	(ABC) transporter
C7J88_RS01060	COG0577	efflux transmembrane transporter activity
C7J88_RS01080	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
C7J88_RS01090	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
C7J88_RS01110	COG0045	succinate-CoA ligase (ADP-forming) activity
C7J88_RS01120	COG0758	DNA mediated transformation
C7J88_RS01125	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
C7J88_RS01130	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
C7J88_RS01135	COG4974	Belongs to the 'phage' integrase family
C7J88_RS01145	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
C7J88_RS01155	COG0052	Belongs to the universal ribosomal protein uS2 family
C7J88_RS01160	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
C7J88_RS01165	COG0528	UMP kinase activity
C7J88_RS01170	COG0233	cytoplasmic translational termination
C7J88_RS01185	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
C7J88_RS01195	COG0442	prolyl-tRNA aminoacylation
C7J88_RS01210	COG0195	Participates in both transcription termination and antitermination
C7J88_RS01215	COG2740	Nucleic-acid-binding protein implicated in transcription termination
C7J88_RS01220	COG1358	cellular component organization or biogenesis
C7J88_RS01225	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
C7J88_RS01230	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
C7J88_RS01235	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
C7J88_RS01240	COG0196	riboflavin kinase activity
C7J88_RS01250	COG1185	polyribonucleotide nucleotidyltransferase activity
C7J88_RS01265	COG2188	Transcriptional regulator
C7J88_RS01270	COG0612	Peptidase, M16
C7J88_RS01275	COG0612	Peptidase, M16
C7J88_RS01280	COG1028	Short-chain dehydrogenase reductase Sdr
C7J88_RS01300	COG1546	Belongs to the CinA family
C7J88_RS01300	COG1058	Belongs to the CinA family
C7J88_RS01305	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
C7J88_RS01310	COG1418	mRNA catabolic process
C7J88_RS01315	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
C7J88_RS01330	COG1692	metallophosphoesterase
C7J88_RS01335	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
C7J88_RS01335	COG0674	pyruvate-flavodoxin oxidoreductase activity
C7J88_RS01340	COG1013	pyruvate-flavodoxin oxidoreductase activity
C7J88_RS01345	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
C7J88_RS01350	COG4550	Control of competence regulator ComK, YlbF/YmcA
C7J88_RS01365	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
C7J88_RS01370	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
C7J88_RS01375	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
C7J88_RS01385	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
C7J88_RS01400	COG1923	regulation of RNA biosynthetic process
C7J88_RS01405	COG0386	Belongs to the glutathione peroxidase family
C7J88_RS01410	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
C7J88_RS01415	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
C7J88_RS01420	COG0789	Transcriptional regulator
C7J88_RS01465	COG0589	response to stress
C7J88_RS01475	COG0006	proline dipeptidase activity
C7J88_RS01480	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
C7J88_RS01490	COG4109	DRTGG domain
C7J88_RS01495	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
C7J88_RS01505	COG0281	malic enzyme
C7J88_RS01510	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
C7J88_RS01515	COG0825	malonyl-CoA metabolic process
C7J88_RS01525	COG0205	6-phosphofructokinase activity
C7J88_RS01530	COG0469	pyruvate kinase activity
C7J88_RS01535	COG0372	Belongs to the citrate synthase family
C7J88_RS01545	COG0745	RESPONSE REGULATOR receiver
C7J88_RS01550	COG5002	protein histidine kinase activity
C7J88_RS01555	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
C7J88_RS01555	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
C7J88_RS01560	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
C7J88_RS01565	COG0237	dephospho-CoA kinase activity
C7J88_RS01575	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
C7J88_RS01580	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
C7J88_RS01585	COG3611	Membrane attachment protein
C7J88_RS01590	COG1484	DNA-dependent DNA replication
C7J88_RS01600	COG0833	amino acid
C7J88_RS01605	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
C7J88_RS01610	COG0291	Belongs to the bacterial ribosomal protein bL35 family
C7J88_RS01620	COG4112	unkown
C7J88_RS01630	COG0544	peptidyl-prolyl cis-trans isomerase activity
C7J88_RS01645	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
C7J88_RS01655	COG0181	hydroxymethylbilane synthase activity
C7J88_RS01670	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
C7J88_RS01680	COG2818	Glycosylase
C7J88_RS01685	COG0525	valine-tRNA ligase activity
C7J88_RS01690	COG0285	dihydrofolate synthase activity
C7J88_RS01695	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
C7J88_RS01700	COG2003	Belongs to the UPF0758 family
C7J88_RS01710	COG1792	Involved in formation and maintenance of cell shape
C7J88_RS01720	COG0261	This protein binds to 23S rRNA in the presence of protein L20
C7J88_RS01725	COG2868	ribosomal protein
C7J88_RS01740	COG4492	Belongs to the UPF0735 family
C7J88_RS01745	COG0632	four-way junction helicase activity
C7J88_RS01750	COG2255	four-way junction helicase activity
C7J88_RS01765	COG1862	Preprotein translocase
C7J88_RS01770	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
C7J88_RS01770	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
C7J88_RS01775	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
C7J88_RS01775	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
C7J88_RS01780	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
C7J88_RS01790	COG1490	D-aminoacyl-tRNA deacylase activity
C7J88_RS01805	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
C7J88_RS01815	COG1733	regulation of RNA biosynthetic process
C7J88_RS01825	COG0702	epimerase
C7J88_RS01860	COG0444	Belongs to the ABC transporter superfamily
C7J88_RS01865	COG4608	Belongs to the ABC transporter superfamily
C7J88_RS01870	COG0601	transmembrane transport
C7J88_RS01875	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C7J88_RS01880	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
C7J88_RS01885	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
C7J88_RS01890	COG1959	2 iron, 2 sulfur cluster binding
C7J88_RS01910	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C7J88_RS01915	COG1104	cysteine desulfurase activity
C7J88_RS01920	COG0482	sulfurtransferase activity
C7J88_RS01930	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
C7J88_RS01935	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
C7J88_RS01940	COG4472	Bacterial protein of unknown function (DUF965)
C7J88_RS01945	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
C7J88_RS01950	COG3906	Belongs to the UPF0473 family
C7J88_RS01955	COG4122	O-methyltransferase activity
C7J88_RS01960	COG0826	peptidase U32
C7J88_RS01965	COG0826	peptidase U32
C7J88_RS01970	COG0572	uridine kinase
C7J88_RS01980	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
C7J88_RS01985	COG1984	allophanate hydrolase subunit 2
C7J88_RS01990	COG0511	ligase activity, forming carbon-carbon bonds
C7J88_RS01995	COG0439	Biotin carboxylase
C7J88_RS02000	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
C7J88_RS02005	COG1914	H( )-stimulated, divalent metal cation uptake system
C7J88_RS02010	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
C7J88_RS02015	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
C7J88_RS02020	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
C7J88_RS02025	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
C7J88_RS02030	COG1534	Rna-binding protein
C7J88_RS02040	COG1713	HD superfamily hydrolase involved in NAD metabolism
C7J88_RS02045	COG0799	negative regulation of ribosome biogenesis
C7J88_RS02050	COG2226	methyltransferase
C7J88_RS02055	COG1596	polysaccharide export
C7J88_RS02055	COG1555	photosystem II stabilization
C7J88_RS02060	COG2131	deaminase
C7J88_RS02065	COG2333	competence protein COMEC
C7J88_RS02065	COG0658	competence protein
C7J88_RS02070	COG1466	dna polymerase III delta subunit
C7J88_RS02075	COG0268	Binds directly to 16S ribosomal RNA
C7J88_RS02085	COG0635	Involved in the biosynthesis of porphyrin-containing compound
C7J88_RS02090	COG1420	regulation of RNA biosynthetic process
C7J88_RS02105	COG0484	heat shock protein binding
C7J88_RS02115	COG1385	rRNA (uridine-N3-)-methyltransferase activity
C7J88_RS02120	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
C7J88_RS02130	COG1030	water channel activity
C7J88_RS02135	COG4864	UPF0365 protein
C7J88_RS02145	COG1702	phosphate starvation-inducible protein PhoH
C7J88_RS02155	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
C7J88_RS02160	COG0295	cytidine deaminase activity
C7J88_RS02170	COG1381	Involved in DNA repair and RecF pathway recombination
C7J88_RS02175	COG0423	glycine-tRNA ligase activity
C7J88_RS02180	COG0517	IMP dehydrogenase activity
C7J88_RS02185	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
C7J88_RS02190	COG0358	DNA primase activity
C7J88_RS02195	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
C7J88_RS02200	COG2384	SAM-dependent methyltransferase
C7J88_RS02210	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
C7J88_RS02215	COG0513	Belongs to the DEAD box helicase family
C7J88_RS02220	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
C7J88_RS02225	COG1121	(ABC) transporter
C7J88_RS02230	COG1108	ABC-type Mn2 Zn2 transport systems permease components
C7J88_RS02240	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
C7J88_RS02245	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
C7J88_RS02250	COG0768	penicillin binding
C7J88_RS02260	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
C7J88_RS02265	COG0705	Rhomboid family
C7J88_RS02265	COG0457	Tetratricopeptide repeat
C7J88_RS02270	COG4483	Protein conserved in bacteria
C7J88_RS02275	COG1940	carbohydrate kinase activity
C7J88_RS02280	COG0011	TIGRFAM Protein of
C7J88_RS02285	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C7J88_RS02290	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
C7J88_RS02305	COG4537	Required for transformation and DNA binding
C7J88_RS02325	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
C7J88_RS02330	COG0404	The glycine cleavage system catalyzes the degradation of glycine
C7J88_RS02340	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
C7J88_RS02345	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
C7J88_RS02350	COG0095	Lipoate-protein ligase
C7J88_RS02365	COG0006	proline dipeptidase activity
C7J88_RS02370	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
C7J88_RS02375	COG0511	ligase activity, forming carbon-carbon bonds
C7J88_RS02380	COG0439	Biotin carboxylase
C7J88_RS02385	COG1302	Protein conserved in bacteria
C7J88_RS02390	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
C7J88_RS02395	COG1570	exodeoxyribonuclease VII activity
C7J88_RS02410	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
C7J88_RS02415	COG1438	arginine binding
C7J88_RS02420	COG0497	DNA recombination
C7J88_RS02425	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C7J88_RS02430	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
C7J88_RS02435	COG0022	dehydrogenase e1 component
C7J88_RS02440	COG0508	dehydrogenase complex catalyzes the overall conversion of
C7J88_RS02450	COG4129	membrane
C7J88_RS02455	COG2195	Cleaves the N-terminal amino acid of tripeptides
C7J88_RS02470	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
C7J88_RS02475	COG1234	tRNA 3'-trailer cleavage
C7J88_RS02480	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
C7J88_RS02485	COG0300	oxidoreductase activity
C7J88_RS02490	COG0667	Aldo Keto reductase
C7J88_RS02495	COG0494	nUDIX hydrolase
C7J88_RS02500	COG0735	belongs to the Fur family
C7J88_RS02505	COG4974	Belongs to the 'phage' integrase family
C7J88_RS02515	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
C7J88_RS02520	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
C7J88_RS02525	COG1187	pseudouridine synthase activity
C7J88_RS02530	COG0745	RESPONSE REGULATOR receiver
C7J88_RS02535	COG5002	protein histidine kinase activity
C7J88_RS02545	COG1141	Ferredoxin
C7J88_RS02555	COG0514	ATP-dependent DNA helicase (RecQ)
C7J88_RS02565	COG0492	ferredoxin-NADP+ reductase activity
C7J88_RS02575	COG0252	asparaginase activity
C7J88_RS02580	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
C7J88_RS02585	COG0539	negative regulation of cytoplasmic translation
C7J88_RS02595	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
C7J88_RS02610	COG2226	methyltransferase
C7J88_RS02615	COG0142	geranyltranstransferase activity
C7J88_RS02635	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
C7J88_RS02640	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
C7J88_RS02645	COG0457	Tetratricopeptide repeat
C7J88_RS02660	COG2738	Putative neutral zinc metallopeptidase
C7J88_RS02665	COG1694	Mazg nucleotide pyrophosphohydrolase
C7J88_RS02670	COG0438	transferase activity, transferring glycosyl groups
C7J88_RS02675	COG0617	tRNA 3'-terminal CCA addition
C7J88_RS02690	COG0017	Asparaginyl-tRNA synthetase
C7J88_RS02695	COG3935	DnaD domain protein
C7J88_RS02700	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
C7J88_RS02715	COG4499	WXG100 protein secretion system (Wss), protein YukC
C7J88_RS02715	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
C7J88_RS02730	COG4474	Belongs to the UPF0398 family
C7J88_RS02735	COG3599	regulation of cell shape
C7J88_RS02745	COG0116	Belongs to the methyltransferase superfamily
C7J88_RS02750	COG2962	Rard protein
C7J88_RS02755	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
C7J88_RS02760	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
C7J88_RS02770	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
C7J88_RS02780	COG1413	lyase activity
C7J88_RS02815	COG2190	(PTS) system
C7J88_RS02820	COG4479	Belongs to the UPF0346 family
C7J88_RS02825	COG0793	Belongs to the peptidase S41A family
C7J88_RS02840	COG0671	phosphoesterase, PA-phosphatase related
C7J88_RS02845	COG0745	RESPONSE REGULATOR receiver
C7J88_RS02850	COG5002	protein histidine kinase activity
C7J88_RS02855	COG0567	Dehydrogenase, E1 component
C7J88_RS02875	COG0714	Associated with various cellular activities
C7J88_RS02880	COG4548	von Willebrand factor, type A
C7J88_RS02885	COG1114	Component of the transport system for branched-chain amino acids
C7J88_RS02890	COG3853	Toxic anion resistance protein (TelA)
C7J88_RS02925	COG1473	amidohydrolase
C7J88_RS02935	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
C7J88_RS02940	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
C7J88_RS02945	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
C7J88_RS02950	COG0488	(ABC) transporter
C7J88_RS02955	COG2996	Protein conserved in bacteria
C7J88_RS02960	COG1164	Oligoendopeptidase f
C7J88_RS02970	COG2348	transferase activity, transferring amino-acyl groups
C7J88_RS02975	COG2348	transferase activity, transferring amino-acyl groups
C7J88_RS02980	COG0287	Prephenate dehydrogenase
C7J88_RS02985	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
C7J88_RS03015	COG0628	permease
C7J88_RS03025	COG3711	transcriptional antiterminator
C7J88_RS03030	COG1115	amino acid carrier protein
C7J88_RS03035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
C7J88_RS03045	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
C7J88_RS03050	COG4841	protein insertion into membrane
C7J88_RS03055	COG0824	Thioesterase
C7J88_RS03065	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
C7J88_RS03070	COG1970	mechanosensitive ion channel activity
C7J88_RS03080	COG0419	ATPase involved in DNA repair
C7J88_RS03090	COG4846	Membrane protein involved in cytochrome C biogenesis
C7J88_RS03095	COG3763	UPF0154 protein
C7J88_RS03105	COG4224	UPF0291 protein
C7J88_RS03115	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
C7J88_RS03120	COG0516	GMP reductase activity
C7J88_RS03125	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
C7J88_RS03135	COG0753	catalase activity
C7J88_RS03140	COG0833	amino acid
C7J88_RS03150	COG0561	phosphatase activity
C7J88_RS03155	COG0083	homoserine kinase activity
C7J88_RS03160	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
C7J88_RS03165	COG0460	homoserine dehydrogenase
C7J88_RS03170	COG0527	aspartate kinase activity
C7J88_RS03180	COG1525	nuclease
C7J88_RS03195	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
C7J88_RS03200	COG0827	DNA restriction-modification system
C7J88_RS03205	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
C7J88_RS03210	COG1714	RDD family
C7J88_RS03215	COG0616	signal peptide processing
C7J88_RS03225	COG0301	tRNA thio-modification
C7J88_RS03230	COG1104	cysteine desulfurase activity
C7J88_RS03235	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
C7J88_RS03240	COG1956	GAF domain-containing protein
C7J88_RS03255	COG0584	glycerophosphoryl diester phosphodiesterase
C7J88_RS03265	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
C7J88_RS03270	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
C7J88_RS03280	COG0204	Acyl-transferase
C7J88_RS03285	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C7J88_RS03295	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
C7J88_RS03315	COG0561	phosphatase activity
C7J88_RS03320	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
C7J88_RS03350	COG2759	Belongs to the formate--tetrahydrofolate ligase family
C7J88_RS03355	COG1609	Transcriptional regulator
C7J88_RS03360	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
C7J88_RS03360	COG1605	Chorismate mutase
C7J88_RS03370	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
C7J88_RS03375	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
C7J88_RS03380	COG1674	ftsk spoiiie
C7J88_RS03385	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C7J88_RS03390	COG4848	Belongs to the UPF0354 family
C7J88_RS03395	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C7J88_RS03400	COG1363	Peptidase, m42
C7J88_RS03410	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C7J88_RS03420	COG0510	thiamine kinase activity
C7J88_RS03425	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
C7J88_RS03430	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
C7J88_RS03440	COG1187	pseudouridine synthase activity
C7J88_RS03445	COG2244	polysaccharide biosynthetic process
C7J88_RS03450	COG2081	HI0933 family
C7J88_RS03455	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
C7J88_RS03465	COG2814	Major facilitator Superfamily
C7J88_RS03470	COG1242	4 iron, 4 sulfur cluster binding
C7J88_RS03475	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
C7J88_RS03495	COG0039	L-malate dehydrogenase activity
C7J88_RS03500	COG2267	carboxylic ester hydrolase activity
C7J88_RS03505	COG0506	proline dehydrogenase activity
C7J88_RS03510	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
C7J88_RS03515	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
C7J88_RS03515	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
C7J88_RS03525	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
C7J88_RS03525	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
C7J88_RS03535	COG5632	N-Acetylmuramoyl-L-alanine amidase
C7J88_RS03535	COG3266	domain, Protein
C7J88_RS03535	COG4193	domain, Protein
C7J88_RS03560	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
C7J88_RS03570	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
C7J88_RS03575	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
C7J88_RS03585	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
C7J88_RS03590	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
C7J88_RS03595	COG1506	peptidase
C7J88_RS03600	COG0494	nUDIX hydrolase
C7J88_RS03605	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
C7J88_RS03615	COG0318	PFAM AMP-dependent synthetase and ligase
C7J88_RS03685	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
C7J88_RS03690	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
C7J88_RS03695	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
C7J88_RS03700	COG2329	Antibiotic biosynthesis monooxygenase
C7J88_RS03710	COG1131	(ABC) transporter
C7J88_RS03715	COG0537	adenosine 5'-monophosphoramidase activity
C7J88_RS03735	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
C7J88_RS03740	COG3481	metal-dependent phosphohydrolase, HD sub domain
C7J88_RS03750	COG0420	3'-5' exonuclease activity
C7J88_RS03775	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
C7J88_RS03780	COG2197	response regulator
C7J88_RS03785	COG4585	Histidine kinase
C7J88_RS03785	COG2203	Gaf domain
C7J88_RS03790	COG0564	pseudouridine synthase activity
C7J88_RS03800	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
C7J88_RS03805	COG0248	Ppx GppA phosphatase
C7J88_RS03810	COG0114	fumarate hydratase activity
C7J88_RS03820	COG0363	glucosamine-6-phosphate deaminase activity
C7J88_RS03825	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
C7J88_RS03835	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
C7J88_RS03840	COG1126	abc transporter atp-binding protein
C7J88_RS03845	COG0765	amino acid transport
C7J88_RS03990	COG0735	belongs to the Fur family
C7J88_RS04000	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
C7J88_RS04005	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
C7J88_RS04010	COG4129	membrane
C7J88_RS04020	COG3557	Belongs to the UPF0374 family
C7J88_RS04025	COG1194	a g-specific adenine glycosylase
C7J88_RS04030	COG1988	membrane-bound metal-dependent
C7J88_RS04040	COG1388	LysM domain
C7J88_RS04040	COG1134	teichoic acid transport
C7J88_RS04050	COG2137	regulation of response to DNA damage stimulus
C7J88_RS04055	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
C7J88_RS04060	COG0028	Belongs to the TPP enzyme family
C7J88_RS04065	COG0693	protein deglycase activity
C7J88_RS04070	COG0535	radical SAM domain protein
C7J88_RS04075	COG1607	acyl-coa hydrolase
C7J88_RS04080	COG2309	aminopeptidase activity
C7J88_RS04085	COG4840	Belongs to the UPF0435 family
C7J88_RS04100	COG1295	ribonuclease BN
C7J88_RS04105	COG0288	reversible hydration of carbon dioxide
C7J88_RS04130	COG0024	Methionine aminopeptidase
C7J88_RS04135	COG4129	membrane
C7J88_RS04150	COG1528	Iron-storage protein
C7J88_RS04160	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
C7J88_RS04175	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C7J88_RS04185	COG0656	L-ascorbic acid biosynthetic process
C7J88_RS04200	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
C7J88_RS04210	COG3177	Filamentation induced by cAMP protein fic
C7J88_RS04215	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
C7J88_RS04220	COG1597	lipid kinase activity
C7J88_RS04225	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
C7J88_RS04235	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
C7J88_RS04240	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
C7J88_RS04245	COG4851	CamS sex pheromone cAM373 precursor
C7J88_RS04260	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
C7J88_RS04265	COG1876	peptidase activity
C7J88_RS04270	COG4496	protein, YerC YecD
C7J88_RS04290	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
C7J88_RS04300	COG0077	Prephenate dehydratase
C7J88_RS04310	COG1335	isochorismatase
C7J88_RS04315	COG1227	inorganic diphosphatase activity
C7J88_RS04325	COG1012	belongs to the aldehyde dehydrogenase family
C7J88_RS04330	COG3832	glyoxalase III activity
C7J88_RS04335	COG2706	6-phosphogluconolactonase activity
C7J88_RS04360	COG2610	gluconate transmembrane transporter activity
C7J88_RS04380	COG1131	(ABC) transporter
C7J88_RS04395	COG1131	(ABC) transporter
C7J88_RS04400	COG1725	Transcriptional regulator
C7J88_RS04410	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
C7J88_RS04415	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
C7J88_RS04440	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
C7J88_RS04450	COG1064	alcohol dehydrogenase
C7J88_RS04460	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
C7J88_RS04470	COG4512	PFAM Accessory gene regulator B
C7J88_RS04495	COG1621	beta-fructofuranosidase activity
C7J88_RS04500	COG1609	Transcriptional regulator
C7J88_RS04505	COG0425	Belongs to the sulfur carrier protein TusA family
C7J88_RS04510	COG2391	methyltransferase activity
C7J88_RS04515	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
C7J88_RS04520	COG0488	(ABC) transporter
C7J88_RS04525	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
C7J88_RS04530	COG0456	acetyltransferase
C7J88_RS04535	COG1214	PFAM Peptidase M22, glycoprotease
C7J88_RS04540	COG0802	atpase or kinase
C7J88_RS04545	COG0129	dihydroxy-acid dehydratase activity
C7J88_RS04550	COG0028	Belongs to the TPP enzyme family
C7J88_RS04565	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
C7J88_RS04570	COG0473	3-isopropylmalate dehydrogenase activity
C7J88_RS04575	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
C7J88_RS04580	COG0066	3-isopropylmalate dehydratase activity
C7J88_RS04620	COG3091	SprT-like family
C7J88_RS04625	COG2183	response to ionizing radiation
C7J88_RS04630	COG1191	sigma factor activity
C7J88_RS04645	COG2208	phosphoserine phosphatase activity
C7J88_RS04650	COG2337	Toxic component of a toxin-antitoxin (TA) module
C7J88_RS04690	COG0513	Belongs to the DEAD box helicase family
C7J88_RS04695	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
C7J88_RS04700	COG1181	Belongs to the D-alanine--D-alanine ligase family
C7J88_RS04705	COG0772	Belongs to the SEDS family
C7J88_RS04710	COG2217	Heavy metal translocating P-type atpase
C7J88_RS04715	COG2608	mercury ion transmembrane transporter activity
C7J88_RS04725	COG1937	Protein conserved in bacteria
C7J88_RS04735	COG1418	mRNA catabolic process
C7J88_RS04740	COG0706	membrane insertase activity
C7J88_RS04745	COG0352	thiamine-phosphate diphosphorylase activity
C7J88_RS04750	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
C7J88_RS04770	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
C7J88_RS04780	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
C7J88_RS04805	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
C7J88_RS04810	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
C7J88_RS04815	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
C7J88_RS04820	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
C7J88_RS04825	COG0356	it plays a direct role in the translocation of protons across the membrane
C7J88_RS04835	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
C7J88_RS04840	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
C7J88_RS04845	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
C7J88_RS04850	COG4475	Protein of unknown function (DUF436)
C7J88_RS04855	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
C7J88_RS04860	COG0009	L-threonylcarbamoyladenylate synthase
C7J88_RS04865	COG2890	protein-(glutamine-N5) methyltransferase activity
C7J88_RS04870	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
C7J88_RS04880	COG0254	rRNA binding
C7J88_RS04885	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
C7J88_RS04900	COG1733	regulation of RNA biosynthetic process
C7J88_RS04905	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
C7J88_RS04910	COG0191	fructose-bisphosphate aldolase activity
C7J88_RS04915	COG4821	SIS domain
C7J88_RS04920	COG2271	Major facilitator Superfamily
C7J88_RS04925	COG0504	CTP synthase activity
C7J88_RS04935	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C7J88_RS04945	COG5146	pantothenate kinase activity
C7J88_RS04965	COG1854	S-ribosylhomocysteine lyase activity
C7J88_RS04975	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
C7J88_RS04980	COG0813	purine-nucleoside phosphorylase activity
C7J88_RS04985	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C7J88_RS04995	COG1757	Na H antiporter
C7J88_RS05010	COG2186	Transcriptional regulator
C7J88_RS05025	COG1119	ATPase activity
C7J88_RS05050	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
C7J88_RS05060	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
C7J88_RS05115	COG0489	protein tyrosine kinase activity
C7J88_RS05120	COG2814	Major facilitator Superfamily
C7J88_RS05135	COG1272	protein, Hemolysin III
C7J88_RS05145	COG1988	membrane-bound metal-dependent
C7J88_RS05155	COG3314	Sporulation integral membrane protein YlbJ
C7J88_RS05160	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C7J88_RS05165	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C7J88_RS05170	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
C7J88_RS05175	COG3457	Alanine racemase
C7J88_RS05180	COG4264	IucA IucC family
C7J88_RS05185	COG2814	Major facilitator Superfamily
C7J88_RS05190	COG4264	IucA IucC family
C7J88_RS05195	COG2814	Major facilitator Superfamily
C7J88_RS05200	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
C7J88_RS05215	COG1302	Protein conserved in bacteria
C7J88_RS05250	COG5002	protein histidine kinase activity
C7J88_RS05260	COG3850	Histidine kinase
C7J88_RS05260	COG5002	protein histidine kinase activity
C7J88_RS05265	COG0745	RESPONSE REGULATOR receiver
C7J88_RS05275	COG1929	Belongs to the glycerate kinase type-1 family
C7J88_RS05280	COG1126	abc transporter atp-binding protein
C7J88_RS05285	COG0765	amino acid transport
C7J88_RS05290	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C7J88_RS05295	COG2315	Protein conserved in bacteria
C7J88_RS05335	COG0101	tRNA pseudouridine synthase activity
C7J88_RS05345	COG1122	ATPase activity
C7J88_RS05355	COG0203	ribosomal protein L17
C7J88_RS05360	COG0202	RNA polymerase activity
C7J88_RS05365	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
C7J88_RS05375	COG0257	Belongs to the bacterial ribosomal protein bL36 family
C7J88_RS05390	COG0201	protein transport
C7J88_RS05400	COG1841	ribosomal large subunit assembly
C7J88_RS05415	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
C7J88_RS05425	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
C7J88_RS05435	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
C7J88_RS05450	COG0255	Belongs to the universal ribosomal protein uL29 family
C7J88_RS05455	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
C7J88_RS05460	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
C7J88_RS05465	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
C7J88_RS05470	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
C7J88_RS05480	COG0089	rRNA binding
C7J88_RS05485	COG0088	Forms part of the polypeptide exit tunnel
C7J88_RS05490	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
C7J88_RS05505	COG2252	PERMEase
C7J88_RS05530	COG0436	Aminotransferase
C7J88_RS05535	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
C7J88_RS05540	COG2348	transferase activity, transferring amino-acyl groups
C7J88_RS05550	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
C7J88_RS05555	COG0746	molybdenum cofactor guanylyltransferase activity
C7J88_RS05565	COG0314	molybdopterin synthase activity
C7J88_RS05570	COG1763	Mo-molybdopterin cofactor biosynthetic process
C7J88_RS05575	COG0303	'Molybdopterin
C7J88_RS05585	COG0521	Mo-molybdopterin cofactor biosynthetic process
C7J88_RS05590	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
C7J88_RS05595	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
C7J88_RS05600	COG4149	molybdate abc transporter
C7J88_RS05605	COG0725	ABC transporter, periplasmic molybdate-binding protein
C7J88_RS05615	COG1902	pentaerythritol trinitrate reductase activity
C7J88_RS05615	COG0446	pyridine nucleotide-disulphide oxidoreductase
C7J88_RS05620	COG4221	oxidoreductase activity
C7J88_RS05625	COG0596	Alpha beta hydrolase
C7J88_RS05645	COG1268	BioY protein
C7J88_RS05650	COG1940	carbohydrate kinase activity
C7J88_RS05665	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
C7J88_RS05670	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C7J88_RS05675	COG2832	Protein of unknown function (DUF454)
C7J88_RS05680	COG1960	acyl-CoA dehydrogenase activity
C7J88_RS05715	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
C7J88_RS05740	COG3383	formate dehydrogenase (NAD+) activity
C7J88_RS05745	COG1316	TRANSCRIPTIONal
C7J88_RS05770	COG1113	amino acid transport
C7J88_RS05790	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
C7J88_RS05795	COG0346	lactoylglutathione lyase activity
C7J88_RS05805	COG0385	Bile acid
C7J88_RS05825	COG1473	amidohydrolase
C7J88_RS05830	COG0659	secondary active sulfate transmembrane transporter activity
C7J88_RS05835	COG1228	amidohydrolase
C7J88_RS05845	COG3314	Sporulation integral membrane protein YlbJ
C7J88_RS05850	COG0583	DNA-binding transcription factor activity
C7J88_RS05860	COG1266	CAAX protease self-immunity
C7J88_RS05870	COG1476	TRANSCRIPTIONal
C7J88_RS05875	COG2017	converts alpha-aldose to the beta-anomer
C7J88_RS05880	COG1742	UPF0060 membrane protein
C7J88_RS05885	COG1668	transmembrane transport
C7J88_RS05890	COG4152	abc transporter atp-binding protein
C7J88_RS05910	COG3152	Membrane
C7J88_RS05915	COG2094	Belongs to the DNA glycosylase MPG family
C7J88_RS05930	COG1695	Transcriptional regulator
C7J88_RS05940	COG2207	Transcriptional regulator
C7J88_RS05945	COG0786	glutamate:sodium symporter activity
C7J88_RS05950	COG0523	cobalamin synthesis protein
C7J88_RS05960	COG0039	L-malate dehydrogenase activity
C7J88_RS05980	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
C7J88_RS05985	COG4640	response to antibiotic
C7J88_RS06000	COG1136	(ABC) transporter
C7J88_RS06005	COG0577	efflux transmembrane transporter activity
C7J88_RS06015	COG3850	Histidine kinase
C7J88_RS06015	COG5002	protein histidine kinase activity
C7J88_RS06020	COG0579	oxidoreductase
C7J88_RS06030	COG1620	l-lactate permease
C7J88_RS06045	COG0604	alcohol dehydrogenase
C7J88_RS06070	COG1283	sodium-dependent phosphate transmembrane transporter activity
C7J88_RS06080	COG1263	PTS System
C7J88_RS06080	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C7J88_RS06095	COG2807	transmembrane transport
C7J88_RS06105	COG0697	spore germination
C7J88_RS06110	COG1363	Peptidase, m42
C7J88_RS06120	COG4187	Peptidase family M20/M25/M40
C7J88_RS06130	COG3591	Belongs to the peptidase S1B family
C7J88_RS06150	COG2197	response regulator
C7J88_RS06155	COG4585	Histidine kinase
C7J88_RS06165	COG2181	nitrate reductase activity
C7J88_RS06170	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
C7J88_RS06175	COG1140	nitrate reductase beta subunit
C7J88_RS06180	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
C7J88_RS06185	COG0737	Belongs to the 5'-nucleotidase family
C7J88_RS06190	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
C7J88_RS06190	COG1648	precorrin-2 dehydrogenase activity
C7J88_RS06195	COG2146	nitrite reductase [NAD(P)H] activity
C7J88_RS06200	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
C7J88_RS06210	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
C7J88_RS06215	COG0454	-acetyltransferase
C7J88_RS06230	COG0471	metal ion transport
C7J88_RS06250	COG1760	l-serine dehydratase
C7J88_RS06255	COG1760	l-serine dehydratase
C7J88_RS06275	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
C7J88_RS06285	COG1126	abc transporter atp-binding protein
C7J88_RS06290	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C7J88_RS06295	COG0765	amino acid transport
C7J88_RS06300	COG0765	amino acid transport
C7J88_RS06315	COG1929	Belongs to the glycerate kinase type-1 family
C7J88_RS06320	COG3764	Sortase (surface protein transpeptidase)
C7J88_RS06330	COG2271	Major facilitator Superfamily
C7J88_RS06335	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
C7J88_RS06340	COG1115	amino acid carrier protein
C7J88_RS06345	COG1132	(ABC) transporter
C7J88_RS06350	COG1132	(ABC) transporter
C7J88_RS06360	COG0159	tryptophan synthase activity
C7J88_RS06365	COG0133	tryptophan synthase activity
C7J88_RS06370	COG0135	phosphoribosylanthranilate isomerase activity
C7J88_RS06375	COG0134	indole-3-glycerol-phosphate synthase activity
C7J88_RS06380	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
C7J88_RS06390	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
C7J88_RS06430	COG1028	Short-chain dehydrogenase reductase Sdr
C7J88_RS06440	COG2814	Major facilitator Superfamily
C7J88_RS06445	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
C7J88_RS06465	COG3942	CHAP domain
C7J88_RS06475	COG2357	RelA SpoT domain protein
C7J88_RS06480	COG0778	Nitroreductase
C7J88_RS06490	COG4607	ABC-type enterochelin transport system periplasmic component
C7J88_RS06495	COG4604	ABC transporter, ATP-binding protein
C7J88_RS06500	COG4605	iron ion homeostasis
C7J88_RS06505	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C7J88_RS06520	COG0583	DNA-binding transcription factor activity
C7J88_RS06525	COG3189	MarR family transcriptional regulator
C7J88_RS06540	COG1136	(ABC) transporter
C7J88_RS06540	COG0577	efflux transmembrane transporter activity
C7J88_RS06545	COG1136	(ABC) transporter
C7J88_RS06565	COG3001	Fructosamine kinase
C7J88_RS06570	COG0778	Nitroreductase
C7J88_RS06585	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C7J88_RS06585	COG1263	PTS System
C7J88_RS06595	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
C7J88_RS06605	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C7J88_RS06610	COG2910	NAD(P)H-binding
C7J88_RS06615	COG1959	2 iron, 2 sulfur cluster binding
C7J88_RS06620	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
C7J88_RS06640	COG3942	CHAP domain
C7J88_RS06640	COG1705	Flagellar rod assembly protein muramidase FlgJ
C7J88_RS06650	COG0789	Transcriptional regulator
C7J88_RS06655	COG0596	Alpha beta hydrolase
C7J88_RS06660	COG2824	Alkylphosphonate utilization operon protein PhnA
C7J88_RS06670	COG1461	Dihydroxyacetone kinase
C7J88_RS06675	COG2376	Dihydroxyacetone kinase
C7J88_RS06685	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
C7J88_RS06695	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
C7J88_RS06700	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
C7J88_RS06705	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
C7J88_RS06710	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
C7J88_RS06715	COG0131	Imidazoleglycerol-phosphate dehydratase
C7J88_RS06725	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
C7J88_RS06730	COG0107	imidazoleglycerol-phosphate synthase activity
C7J88_RS06745	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
C7J88_RS06750	COG1012	belongs to the aldehyde dehydrogenase family
C7J88_RS06755	COG1510	regulation of RNA biosynthetic process
C7J88_RS06760	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
C7J88_RS06765	COG2258	MOSC domain
C7J88_RS06770	COG3527	Alpha-acetolactate decarboxylase
C7J88_RS06775	COG1785	Belongs to the alkaline phosphatase family
C7J88_RS06780	COG2814	Major facilitator Superfamily
C7J88_RS06785	COG2226	methyltransferase
C7J88_RS06790	COG1957	nucleoside hydrolase
C7J88_RS06795	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
C7J88_RS06800	COG4221	oxidoreductase activity
C7J88_RS06825	COG0803	Belongs to the bacterial solute-binding protein 9 family
C7J88_RS06825	COG3443	Belongs to the bacterial solute-binding protein 9 family
C7J88_RS06830	COG2873	o-acetylhomoserine
C7J88_RS06835	COG0602	queuosine metabolic process
C7J88_RS06840	COG1328	CTP reductase activity
C7J88_RS06890	COG0626	cystathionine gamma-synthase activity
C7J88_RS06895	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
C7J88_RS06900	COG2272	Belongs to the type-B carboxylesterase lipase family
C7J88_RS06905	COG0733	neurotransmitter:sodium symporter activity
C7J88_RS06915	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
C7J88_RS06920	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
C7J88_RS06920	COG0574	Belongs to the PEP-utilizing enzyme family
C7J88_RS06925	COG1279	arginine transmembrane transporter activity
C7J88_RS06960	COG1073	alpha beta
C7J88_RS06975	COG0518	GMP synthase (glutamine-hydrolyzing) activity
C7J88_RS06975	COG0519	Catalyzes the synthesis of GMP from XMP
C7J88_RS06980	COG0516	GMP reductase activity
C7J88_RS06980	COG0517	IMP dehydrogenase activity
C7J88_RS06985	COG2233	PERMEase
C7J88_RS06990	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
C7J88_RS07005	COG5183	chlorophyll binding
C7J88_RS07010	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C7J88_RS07015	COG1823	symporter activity
C7J88_RS07020	COG0778	Nitroreductase
C7J88_RS07030	COG0450	alkyl hydroperoxide reductase
C7J88_RS07035	COG3634	alkyl hydroperoxide reductase activity
C7J88_RS07045	COG1464	Belongs to the NlpA lipoprotein family
C7J88_RS07055	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
C7J88_RS07060	COG2011	ABC-type metal ion transport system permease component
C7J88_RS07065	COG1464	Belongs to the NlpA lipoprotein family
C7J88_RS07070	COG3037	sugar-specific permease SgaT UlaA
C7J88_RS07080	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C7J88_RS07085	COG3711	transcriptional antiterminator
C7J88_RS07100	COG1473	amidohydrolase
C7J88_RS07125	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
C7J88_RS07135	COG0360	Binds together with S18 to 16S ribosomal RNA
C7J88_RS07140	COG0012	GTP binding
C7J88_RS07145	COG4481	Protein conserved in bacteria
C7J88_RS07150	COG0668	transmembrane transport
C7J88_RS07155	COG1475	DNA binding
C7J88_RS07160	COG0626	cystathionine gamma-synthase activity
C7J88_RS07165	COG0626	cystathionine gamma-synthase activity
C7J88_RS07170	COG0646	methionine synthase
C7J88_RS07170	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
C7J88_RS07175	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
C7J88_RS07195	COG0357	Ribosomal RNA small subunit methyltransferase G
C7J88_RS07200	COG0445	tRNA wobble uridine modification
C7J88_RS07205	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
C7J88_RS07210	COG0594	ribonuclease P activity
C7J88_RS07220	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
C7J88_RS07225	COG0592	DNA-directed DNA polymerase activity
C7J88_RS07230	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
C7J88_RS07240	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
C7J88_RS07245	COG0187	DNA topoisomerase II activity
C7J88_RS07255	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
C7J88_RS07270	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
C7J88_RS07280	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
C7J88_RS07285	COG4241	membrane
C7J88_RS07290	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
C7J88_RS07295	COG0359	binds to the 23S rRNA
C7J88_RS07300	COG0305	Participates in initiation and elongation during chromosome replication
C7J88_RS07305	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
C7J88_RS07310	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
C7J88_RS07330	COG0604	alcohol dehydrogenase
C7J88_RS07330	COG1028	Short-chain dehydrogenase reductase Sdr
C7J88_RS07330	COG3321	synthase
C7J88_RS07340	COG5002	protein histidine kinase activity
C7J88_RS07355	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
C7J88_RS07380	COG0488	(ABC) transporter
C7J88_RS07410	COG0577	efflux transmembrane transporter activity
C7J88_RS07420	COG2314	TM2 domain
C7J88_RS07430	COG0561	phosphatase activity
C7J88_RS07435	COG2723	6-phospho-beta-galactosidase activity
C7J88_RS07440	COG2188	Transcriptional regulator
C7J88_RS07485	COG1619	proteins homologs of microcin C7 resistance protein MccF
C7J88_RS07535	COG2814	Major facilitator Superfamily
C7J88_RS07535	COG0477	Major facilitator Superfamily
C7J88_RS07540	COG1070	Carbohydrate kinase
C7J88_RS07545	COG2115	Belongs to the xylose isomerase family
C7J88_RS07550	COG1846	Transcriptional regulator
C7J88_RS07550	COG1940	carbohydrate kinase activity
C7J88_RS07580	COG2188	Transcriptional regulator
C7J88_RS07585	COG0813	purine-nucleoside phosphorylase activity
C7J88_RS07590	COG2814	Major facilitator Superfamily
C7J88_RS07595	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
C7J88_RS07610	COG3391	amine dehydrogenase activity
C7J88_RS07625	COG1073	alpha beta
C7J88_RS07645	COG0438	transferase activity, transferring glycosyl groups
C7J88_RS07655	COG0110	maltose O-acetyltransferase activity
C7J88_RS07660	COG0583	DNA-binding transcription factor activity
C7J88_RS07685	COG1073	alpha beta
C7J88_RS07730	COG0579	oxidoreductase
C7J88_RS07735	COG1620	l-lactate permease
C7J88_RS07740	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C7J88_RS07740	COG1263	PTS System
C7J88_RS07745	COG0366	Alpha amylase catalytic
C7J88_RS07750	COG2188	Transcriptional regulator
C7J88_RS07765	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
C7J88_RS07770	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
C7J88_RS07775	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
C7J88_RS07795	COG0488	(ABC) transporter
C7J88_RS07800	COG1982	Orn Lys Arg decarboxylase major
C7J88_RS07805	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
C7J88_RS07810	COG3870	Protein conserved in bacteria
C7J88_RS07820	COG1774	PSP1 C-terminal conserved region
C7J88_RS07825	COG4467	Involved in initiation control of chromosome replication
C7J88_RS07830	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
C7J88_RS07835	COG2827	Endonuclease containing a URI domain
C7J88_RS07840	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
C7J88_RS07845	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C7J88_RS07845	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C7J88_RS07850	COG0084	hydrolase, TatD family'
C7J88_RS07855	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
C7J88_RS07860	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
C7J88_RS07865	COG4466	Protein conserved in bacteria
C7J88_RS07870	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
C7J88_RS07875	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
C7J88_RS07880	COG0251	oxidation-reduction process
C7J88_RS07885	COG2088	sporulation resulting in formation of a cellular spore
C7J88_RS07890	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
C7J88_RS07895	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
C7J88_RS07905	COG0193	aminoacyl-tRNA hydrolase activity
C7J88_RS07910	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
C7J88_RS07915	COG2244	polysaccharide biosynthetic process
C7J88_RS07920	COG3956	TIGRFAM MazG family protein
C7J88_RS07925	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
C7J88_RS07935	COG1098	S1 RNA binding domain
C7J88_RS07950	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
C7J88_RS07955	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
C7J88_RS07975	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
C7J88_RS07980	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
C7J88_RS07985	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
C7J88_RS08070	COG1289	transmembrane transporter activity
C7J88_RS08075	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C7J88_RS08080	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
C7J88_RS08085	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
C7J88_RS08090	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
C7J88_RS08095	COG4463	regulation of RNA biosynthetic process
C7J88_RS08100	COG3880	PFAM UvrB UvrC protein
C7J88_RS08105	COG3869	Catalyzes the specific phosphorylation of arginine residues in
C7J88_RS08110	COG0542	response to heat
C7J88_RS08115	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
C7J88_RS08125	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
C7J88_RS08130	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
C7J88_RS08135	COG1045	serine acetyltransferase
C7J88_RS08140	COG0215	cysteine-tRNA ligase activity
C7J88_RS08145	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
C7J88_RS08165	COG0267	Belongs to the bacterial ribosomal protein bL33 family
C7J88_RS08170	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
C7J88_RS08175	COG0250	Participates in transcription elongation, termination and antitermination
C7J88_RS08180	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
C7J88_RS08185	COG0081	regulation of translation
C7J88_RS08195	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
C7J88_RS08205	COG2813	Specifically methylates the guanine in position
C7J88_RS08210	COG0085	RNA polymerase activity
C7J88_RS08215	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
C7J88_RS08225	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
C7J88_RS08230	COG0049	tRNA binding
C7J88_RS08235	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
C7J88_RS08240	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
C7J88_RS08250	COG1473	amidohydrolase
C7J88_RS08265	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
C7J88_RS08280	COG1428	Deoxynucleoside kinase
C7J88_RS08285	COG1428	Deoxynucleoside kinase
C7J88_RS08295	COG0561	phosphatase activity
C7J88_RS08300	COG0431	NADPH-dependent FMN reductase
C7J88_RS08315	COG2207	Transcriptional regulator
C7J88_RS08320	COG0800	Aldolase
C7J88_RS08325	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C7J88_RS08330	COG2211	Major facilitator Superfamily
C7J88_RS08335	COG1904	glucuronate isomerase
C7J88_RS08340	COG1312	Catalyzes the dehydration of D-mannonate
C7J88_RS08345	COG1028	Short-chain dehydrogenase reductase Sdr
C7J88_RS08350	COG3250	beta-galactosidase activity
C7J88_RS08360	COG1469	GTP cyclohydrolase I activity
C7J88_RS08365	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
C7J88_RS08370	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
C7J88_RS08380	COG2190	(PTS) system
C7J88_RS08380	COG1263	PTS System
C7J88_RS08380	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C7J88_RS08390	COG0363	glucosamine-6-phosphate deaminase activity
C7J88_RS08395	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
C7J88_RS08405	COG0318	PFAM AMP-dependent synthetase and ligase
C7J88_RS08410	COG0183	Belongs to the thiolase family
C7J88_RS08430	COG1686	Belongs to the peptidase S11 family
C7J88_RS08440	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
C7J88_RS08450	COG2363	Small membrane protein
C7J88_RS08455	COG0531	amino acid
C7J88_RS08465	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
C7J88_RS08470	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
C7J88_RS08475	COG1116	anion transmembrane transporter activity
C7J88_RS08490	COG1566	PFAM secretion protein HlyD family protein
C7J88_RS08495	COG2814	Major facilitator Superfamily
C7J88_RS08500	COG0095	Lipoate-protein ligase
C7J88_RS08505	COG0280	phosphate acetyltransferase
C7J88_RS08510	COG3253	May function as heme-dependent peroxidase
C7J88_RS08515	COG0531	amino acid
C7J88_RS08530	COG0471	metal ion transport
C7J88_RS08535	COG4844	belongs to the
C7J88_RS08545	COG0456	acetyltransferase
C7J88_RS08550	COG1078	dGTPase activity
C7J88_RS08565	COG0018	arginyl-trna synthetase
C7J88_RS08570	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C7J88_RS08575	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C7J88_RS08585	COG0596	Alpha beta hydrolase
C7J88_RS08630	COG0582	viral genome integration into host DNA
C7J88_RS08635	COG2111	Na H antiporter
C7J88_RS08635	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
C7J88_RS08640	COG2111	Na H antiporter
C7J88_RS08645	COG1006	Multisubunit Na H antiporter MnhC subunit
C7J88_RS08650	COG0651	ATP synthesis coupled electron transport
C7J88_RS08655	COG1863	multisubunit Na H antiporter MnhE subunit
C7J88_RS08660	COG2212	antiporter activity
C7J88_RS08665	COG1320	monovalent cation:proton antiporter activity
C7J88_RS08670	COG0803	Belongs to the bacterial solute-binding protein 9 family
C7J88_RS08675	COG1108	ABC-type Mn2 Zn2 transport systems permease components
C7J88_RS08680	COG1121	(ABC) transporter
C7J88_RS08685	COG1321	iron dependent repressor
C7J88_RS08700	COG1134	teichoic acid transport
C7J88_RS08705	COG1682	transport, permease protein
C7J88_RS08710	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
C7J88_RS08715	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
C7J88_RS08720	COG1686	Belongs to the peptidase S11 family
C7J88_RS08725	COG1132	(ABC) transporter
C7J88_RS08745	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
C7J88_RS08750	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
C7J88_RS08755	COG1120	ATPase activity
C7J88_RS08760	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C7J88_RS08765	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C7J88_RS08775	COG0477	Major facilitator Superfamily
C7J88_RS08780	COG3949	Membrane
C7J88_RS08790	COG0745	RESPONSE REGULATOR receiver
C7J88_RS08795	COG2205	protein histidine kinase activity
C7J88_RS08800	COG1136	(ABC) transporter
C7J88_RS08805	COG0577	efflux transmembrane transporter activity
C7J88_RS08810	COG1392	Phosphate transport regulator
C7J88_RS08815	COG0306	phosphate transporter
C7J88_RS08820	COG3942	CHAP domain
C7J88_RS08820	COG1388	LysM domain
C7J88_RS08840	COG2022	thiamine diphosphate biosynthetic process
C7J88_RS08845	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
C7J88_RS08850	COG0217	transcriptional regulatory protein
C7J88_RS08865	COG0583	DNA-binding transcription factor activity
C7J88_RS08870	COG2814	Major facilitator Superfamily
C7J88_RS08900	COG1611	Belongs to the LOG family
C7J88_RS08915	COG1968	undecaprenyl-diphosphatase activity
C7J88_RS08930	COG4989	oxidoreductase activity
C7J88_RS08940	COG0039	L-malate dehydrogenase activity
C7J88_RS08945	COG1266	CAAX protease self-immunity
C7J88_RS08955	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
C7J88_RS08960	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
C7J88_RS08965	COG1349	DNA-binding transcription factor activity
C7J88_RS08970	COG1105	Belongs to the carbohydrate kinase PfkB family
C7J88_RS08975	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C7J88_RS08975	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C7J88_RS08975	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C7J88_RS08980	COG1253	flavin adenine dinucleotide binding
C7J88_RS08985	COG0463	Glycosyl transferase, family 2
C7J88_RS09000	COG1309	transcriptional regulator
C7J88_RS09020	COG0602	queuosine metabolic process
C7J88_RS09025	COG0720	synthase
C7J88_RS09030	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
C7J88_RS09035	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
C7J88_RS09035	COG0512	Glutamine amidotransferase of anthranilate synthase
C7J88_RS09065	COG1368	sulfuric ester hydrolase activity
C7J88_RS09075	COG0488	(ABC) transporter
C7J88_RS09080	COG0514	ATP-dependent DNA helicase (RecQ)
C7J88_RS09085	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
C7J88_RS09085	COG1215	transferase activity, transferring glycosyl groups
C7J88_RS09090	COG0463	Glycosyl transferase, family 2
C7J88_RS09095	COG1216	Glycosyl transferase, family 2
C7J88_RS09100	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
C7J88_RS09100	COG1215	transferase activity, transferring glycosyl groups
C7J88_RS09105	COG1125	glycine betaine transport
C7J88_RS09105	COG0517	IMP dehydrogenase activity
C7J88_RS09110	COG1174	glycine betaine transport
C7J88_RS09115	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
C7J88_RS09120	COG4502	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
C7J88_RS09125	COG3104	oligopeptide transport
C7J88_RS09150	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
C7J88_RS09155	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
C7J88_RS09165	COG0812	UDP-N-acetylmuramate dehydrogenase activity
C7J88_RS09185	COG1929	Belongs to the glycerate kinase type-1 family
C7J88_RS09205	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
C7J88_RS09235	COG1739	Uncharacterized protein family UPF0029
C7J88_RS09245	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
C7J88_RS09255	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
C7J88_RS09260	COG0653	protein targeting
C7J88_RS09300	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
C7J88_RS09305	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
C7J88_RS09310	COG0110	maltose O-acetyltransferase activity
C7J88_RS09325	COG1660	Displays ATPase and GTPase activities
C7J88_RS09330	COG0391	Required for morphogenesis under gluconeogenic growth conditions
C7J88_RS09335	COG1481	regulation of sporulation
C7J88_RS09345	COG3759	membrane
C7J88_RS09350	COG1278	Cold shock
C7J88_RS09365	COG2514	catechol 2,3-dioxygenase activity
C7J88_RS09375	COG1090	epimerase
C7J88_RS09400	COG0126	phosphoglycerate kinase activity
C7J88_RS09410	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
C7J88_RS09425	COG3949	Membrane
C7J88_RS09435	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
C7J88_RS09440	COG1647	Serine aminopeptidase, S33
C7J88_RS09445	COG0557	exoribonuclease II activity
C7J88_RS09465	COG0675	Transposase, IS605 OrfB family
C7J88_RS09480	COG0675	Transposase, IS605 OrfB family
C7J88_RS09500	COG0675	Transposase, IS605 OrfB family
C7J88_RS09520	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
C7J88_RS09605	COG0305	Participates in initiation and elongation during chromosome replication
C7J88_RS09635	COG0270	DNA (cytosine-5-)-methyltransferase activity
C7J88_RS09680	COG0756	dUTP diphosphatase activity
C7J88_RS09765	COG0739	heme binding
C7J88_RS09785	COG4824	toxin secretion phage lysis holin
C7J88_RS09790	COG3409	Peptidoglycan-binding domain 1 protein
C7J88_RS09790	COG5632	N-Acetylmuramoyl-L-alanine amidase
C7J88_RS09810	COG1764	response to oxidative stress
C7J88_RS09830	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C7J88_RS09835	COG1393	Belongs to the ArsC family
C7J88_RS09850	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
C7J88_RS09855	COG2011	ABC-type metal ion transport system permease component
C7J88_RS09860	COG1464	Belongs to the NlpA lipoprotein family
C7J88_RS09865	COG1464	Belongs to the NlpA lipoprotein family
C7J88_RS09870	COG1464	Belongs to the NlpA lipoprotein family
C7J88_RS09880	COG0396	ATPase activity
C7J88_RS09885	COG0719	Fe-S assembly protein
C7J88_RS09895	COG0822	iron-sulfur transferase activity
C7J88_RS09900	COG0719	Fe-S assembly protein
C7J88_RS09920	COG0456	acetyltransferase
C7J88_RS09925	COG2808	Putative FMN-binding domain
C7J88_RS09930	COG1253	flavin adenine dinucleotide binding
C7J88_RS09935	COG2070	2-Nitropropane dioxygenase
C7J88_RS09940	COG1801	Protein of unknown function DUF72
C7J88_RS09945	COG0730	response to heat
C7J88_RS09950	COG0737	Belongs to the 5'-nucleotidase family
C7J88_RS09955	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
C7J88_RS09960	COG4470	Protein conserved in bacteria
C7J88_RS09970	COG2445	Protein of unknown function DUF86
C7J88_RS09975	COG0647	UMP catabolic process
C7J88_RS09985	COG4837	Protein of unknown function (DUF1462)
C7J88_RS09990	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
C7J88_RS09995	COG1252	NADH dehydrogenase
C7J88_RS10000	COG4844	belongs to the
C7J88_RS10005	COG0316	Belongs to the HesB IscA family
C7J88_RS10010	COG1252	NADH dehydrogenase
C7J88_RS10015	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
C7J88_RS10020	COG2056	Na+-H+ antiporter family
C7J88_RS10025	COG2050	protein possibly involved in aromatic compounds catabolism
C7J88_RS10040	COG1320	monovalent cation:proton antiporter activity
C7J88_RS10045	COG2212	antiporter activity
C7J88_RS10050	COG1863	multisubunit Na H antiporter MnhE subunit
C7J88_RS10055	COG0651	ATP synthesis coupled electron transport
C7J88_RS10060	COG1006	Multisubunit Na H antiporter MnhC subunit
C7J88_RS10065	COG2111	Na H antiporter
C7J88_RS10070	COG2111	Na H antiporter
C7J88_RS10070	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
C7J88_RS10080	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
C7J88_RS10090	COG1846	Transcriptional regulator
C7J88_RS10100	COG1098	S1 RNA binding domain
C7J88_RS10105	COG2249	NAD(P)H dehydrogenase (quinone) activity
C7J88_RS10110	COG1012	belongs to the aldehyde dehydrogenase family
C7J88_RS10125	COG0584	glycerophosphoryl diester phosphodiesterase
C7J88_RS10130	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
C7J88_RS10135	COG0165	Argininosuccinate lyase
C7J88_RS10140	COG0137	argininosuccinate synthase activity
C7J88_RS10145	COG0166	Belongs to the GPI family
C7J88_RS10160	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
C7J88_RS10165	COG1074	ATP-dependent DNA helicase activity
C7J88_RS10170	COG0179	Fumarylacetoacetate (FAA) hydrolase
C7J88_RS10180	COG0446	pyridine nucleotide-disulphide oxidoreductase
C7J88_RS10185	COG0561	phosphatase activity
C7J88_RS10200	COG0542	response to heat
C7J88_RS10205	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
C7J88_RS10230	COG0601	transmembrane transport
C7J88_RS10235	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C7J88_RS10240	COG0444	Belongs to the ABC transporter superfamily
C7J88_RS10245	COG4608	Belongs to the ABC transporter superfamily
C7J88_RS10250	COG4166	transmembrane transport
C7J88_RS10260	COG0180	Tryptophanyl-tRNA synthetase
C7J88_RS10265	COG1393	Belongs to the ArsC family
C7J88_RS10270	COG4862	establishment of competence for transformation
C7J88_RS10280	COG1164	Oligoendopeptidase f
C7J88_RS10285	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
C7J88_RS10290	COG2346	COG2346, Truncated hemoglobins
C7J88_RS10295	COG4116	CYTH
C7J88_RS10305	COG2357	RelA SpoT domain protein
C7J88_RS10310	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
C7J88_RS10315	COG0564	pseudouridine synthase activity
C7J88_RS10320	COG2239	Acts as a magnesium transporter
C7J88_RS10325	COG0569	domain protein
C7J88_RS10325	COG0475	glutathione-regulated potassium exporter activity
C7J88_RS10335	COG0628	permease
C7J88_RS10340	COG1115	amino acid carrier protein
C7J88_RS10350	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
C7J88_RS10355	COG2814	Major facilitator Superfamily
C7J88_RS10360	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
C7J88_RS10365	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
C7J88_RS10375	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP