locus-tag	class	description
BJD96_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
BJD96_RS00010	COG0592	DNA-directed DNA polymerase activity
BJD96_RS00015	COG2501	S4 domain
BJD96_RS00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
BJD96_RS00025	COG0187	DNA topoisomerase II activity
BJD96_RS00030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BJD96_RS00035	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
BJD96_RS00040	COG2986	histidine ammonia-lyase
BJD96_RS00045	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
BJD96_RS00050	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
BJD96_RS00060	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BJD96_RS00070	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
BJD96_RS00075	COG0359	binds to the 23S rRNA
BJD96_RS00080	COG0305	Participates in initiation and elongation during chromosome replication
BJD96_RS00085	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
BJD96_RS00090	COG1819	glycosyl
BJD96_RS00110	COG0477	Major facilitator Superfamily
BJD96_RS00115	COG0745	RESPONSE REGULATOR receiver
BJD96_RS00120	COG5002	protein histidine kinase activity
BJD96_RS00135	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
BJD96_RS00140	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
BJD96_RS00150	COG0640	Transcriptional regulator
BJD96_RS00155	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BJD96_RS00160	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BJD96_RS00265	COG0789	Transcriptional regulator
BJD96_RS00275	COG0702	epimerase
BJD96_RS00280	COG2130	NADP-dependent
BJD96_RS00300	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
BJD96_RS00310	COG1653	transport
BJD96_RS00315	COG1175	transmembrane transport
BJD96_RS00320	COG0395	ABC-type sugar transport system, permease component
BJD96_RS00325	COG3842	ATPase activity
BJD96_RS00340	COG1846	Transcriptional regulator
BJD96_RS00350	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
BJD96_RS00355	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BJD96_RS00360	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BJD96_RS00365	COG1845	cytochrome c oxidase, subunit III
BJD96_RS00370	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
BJD96_RS00395	COG1349	DNA-binding transcription factor activity
BJD96_RS00400	COG1070	Carbohydrate kinase
BJD96_RS00405	COG4806	L-rhamnose isomerase
BJD96_RS00410	COG0235	Class ii aldolase
BJD96_RS00415	COG3254	rhamnose metabolic process
BJD96_RS00420	COG2814	Major facilitator Superfamily
BJD96_RS00425	COG1012	belongs to the aldehyde dehydrogenase family
BJD96_RS00465	COG4565	transcriptional regulatory protein
BJD96_RS00470	COG3493	citrate carrier protein
BJD96_RS00480	COG1846	Transcriptional regulator
BJD96_RS00485	COG3961	Belongs to the TPP enzyme family
BJD96_RS00505	COG1942	4-Oxalocrotonate Tautomerase
BJD96_RS00510	COG4145	pantothenate transmembrane transporter activity
BJD96_RS00520	COG1733	regulation of RNA biosynthetic process
BJD96_RS00525	COG1902	pentaerythritol trinitrate reductase activity
BJD96_RS00540	COG1705	Flagellar rod assembly protein muramidase FlgJ
BJD96_RS00540	COG3942	CHAP domain
BJD96_RS00550	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BJD96_RS00585	COG0702	epimerase
BJD96_RS00590	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
BJD96_RS00625	COG0415	Belongs to the DNA photolyase family
BJD96_RS00630	COG1335	isochorismatase
BJD96_RS00635	COG1522	sequence-specific DNA binding
BJD96_RS00640	COG1733	regulation of RNA biosynthetic process
BJD96_RS00665	COG0583	DNA-binding transcription factor activity
BJD96_RS00670	COG2190	(PTS) system
BJD96_RS00670	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BJD96_RS00670	COG1263	PTS System
BJD96_RS00675	COG2723	6-phospho-beta-galactosidase activity
BJD96_RS00690	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
BJD96_RS00695	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
BJD96_RS00700	COG1595	DNA-templated transcription, initiation
BJD96_RS00710	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BJD96_RS00720	COG1737	Transcriptional regulator
BJD96_RS00725	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BJD96_RS00730	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BJD96_RS00735	COG1447	Phosphotransferase system cellobiose-specific component IIA
BJD96_RS00755	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BJD96_RS00760	COG0471	metal ion transport
BJD96_RS00765	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
BJD96_RS00770	COG1028	Short-chain dehydrogenase reductase Sdr
BJD96_RS00775	COG0583	DNA-binding transcription factor activity
BJD96_RS00790	COG3711	transcriptional antiterminator
BJD96_RS00795	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BJD96_RS00795	COG1263	PTS System
BJD96_RS00795	COG2190	(PTS) system
BJD96_RS00800	COG0438	transferase activity, transferring glycosyl groups
BJD96_RS00805	COG0438	transferase activity, transferring glycosyl groups
BJD96_RS00810	COG1876	peptidase activity
BJD96_RS00820	COG0402	S-adenosylhomocysteine deaminase activity
BJD96_RS00825	COG2723	6-phospho-beta-galactosidase activity
BJD96_RS00830	COG2723	6-phospho-beta-galactosidase activity
BJD96_RS00835	COG1263	PTS System
BJD96_RS00835	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BJD96_RS00835	COG2190	(PTS) system
BJD96_RS00840	COG3711	transcriptional antiterminator
BJD96_RS00845	COG1309	transcriptional regulator
BJD96_RS00850	COG1511	domain protein
BJD96_RS00865	COG2207	Transcriptional regulator
BJD96_RS00870	COG2211	Major facilitator Superfamily
BJD96_RS00875	COG3250	beta-galactosidase activity
BJD96_RS00885	COG2271	Major facilitator Superfamily
BJD96_RS00895	COG3655	Transcriptional regulator
BJD96_RS00905	COG0583	DNA-binding transcription factor activity
BJD96_RS00925	COG0579	oxidoreductase
BJD96_RS00930	COG5295	Hep Hag repeat protein
BJD96_RS00930	COG4932	domain protein
BJD96_RS00950	COG1028	Short-chain dehydrogenase reductase Sdr
BJD96_RS00955	COG1063	alcohol dehydrogenase
BJD96_RS00965	COG1063	alcohol dehydrogenase
BJD96_RS00970	COG3775	system Galactitol-specific IIC component
BJD96_RS00975	COG3414	Phosphotransferase system galactitol-specific IIB component
BJD96_RS00990	COG0471	metal ion transport
BJD96_RS01000	COG2318	DinB family
BJD96_RS01005	COG1388	LysM domain
BJD96_RS01010	COG0564	pseudouridine synthase activity
BJD96_RS01015	COG1388	LysM domain
BJD96_RS01020	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BJD96_RS01030	COG1054	Belongs to the UPF0176 family
BJD96_RS01045	COG1609	Transcriptional regulator
BJD96_RS01055	COG0235	Class ii aldolase
BJD96_RS01060	COG2160	L-arabinose isomerase activity
BJD96_RS01080	COG1511	domain protein
BJD96_RS01080	COG1511	domain protein
BJD96_RS01095	COG2207	Transcriptional regulator
BJD96_RS01095	COG1917	Cupin 2, conserved barrel domain protein
BJD96_RS01105	COG1328	CTP reductase activity
BJD96_RS01115	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
BJD96_RS01120	COG4932	domain protein
BJD96_RS01120	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
BJD96_RS01120	COG3583	domain protein
BJD96_RS01125	COG0431	NADPH-dependent FMN reductase
BJD96_RS01130	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BJD96_RS01135	COG0346	lactoylglutathione lyase activity
BJD96_RS01140	COG1136	(ABC) transporter
BJD96_RS01170	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
BJD96_RS01195	COG0477	Major facilitator Superfamily
BJD96_RS01205	COG2814	Major facilitator Superfamily
BJD96_RS01215	COG0584	glycerophosphoryl diester phosphodiesterase
BJD96_RS01225	COG0668	transmembrane transport
BJD96_RS01235	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
BJD96_RS01245	COG2211	Major facilitator Superfamily
BJD96_RS01250	COG1940	carbohydrate kinase activity
BJD96_RS01250	COG1846	Transcriptional regulator
BJD96_RS01255	COG2115	Belongs to the xylose isomerase family
BJD96_RS01260	COG1070	Carbohydrate kinase
BJD96_RS01265	COG0477	Major facilitator Superfamily
BJD96_RS01265	COG2814	Major facilitator Superfamily
BJD96_RS01275	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BJD96_RS01305	COG0673	inositol 2-dehydrogenase activity
BJD96_RS01315	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
BJD96_RS01320	COG1691	(AIR) carboxylase
BJD96_RS01325	COG1606	tRNA processing
BJD96_RS01330	COG3875	lactate racemase activity
BJD96_RS01345	COG3835	regulator
BJD96_RS01355	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
BJD96_RS01375	COG1476	TRANSCRIPTIONal
BJD96_RS01380	COG2807	transmembrane transport
BJD96_RS01390	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BJD96_RS01395	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BJD96_RS01400	COG1012	belongs to the aldehyde dehydrogenase family
BJD96_RS01405	COG0531	amino acid
BJD96_RS01425	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BJD96_RS01430	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BJD96_RS01435	COG1510	regulation of RNA biosynthetic process
BJD96_RS01440	COG1012	belongs to the aldehyde dehydrogenase family
BJD96_RS01445	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
BJD96_RS01450	COG0803	Belongs to the bacterial solute-binding protein 9 family
BJD96_RS01455	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BJD96_RS01465	COG0772	Belongs to the SEDS family
BJD96_RS01475	COG0778	Nitroreductase
BJD96_RS01480	COG2843	Capsule synthesis protein
BJD96_RS01485	COG1957	nucleoside hydrolase
BJD96_RS01490	COG0477	Major facilitator Superfamily
BJD96_RS01510	COG1131	(ABC) transporter
BJD96_RS01520	COG1349	DNA-binding transcription factor activity
BJD96_RS01525	COG3842	ATPase activity
BJD96_RS01550	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BJD96_RS01555	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
BJD96_RS01560	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
BJD96_RS01565	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
BJD96_RS01575	COG0431	NADPH-dependent FMN reductase
BJD96_RS01585	COG1414	Transcriptional regulator
BJD96_RS01595	COG1063	alcohol dehydrogenase
BJD96_RS01600	COG1620	l-lactate permease
BJD96_RS01605	COG2814	Major facilitator Superfamily
BJD96_RS01615	COG2190	(PTS) system
BJD96_RS01615	COG1263	PTS System
BJD96_RS01615	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BJD96_RS01625	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BJD96_RS01635	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BJD96_RS01660	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BJD96_RS01665	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BJD96_RS01675	COG3037	sugar-specific permease SgaT UlaA
BJD96_RS01685	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BJD96_RS01690	COG1464	Belongs to the NlpA lipoprotein family
BJD96_RS01695	COG0039	L-malate dehydrogenase activity
BJD96_RS01700	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BJD96_RS01700	COG3711	transcriptional antiterminator
BJD96_RS01705	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BJD96_RS01705	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BJD96_RS01705	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BJD96_RS01710	COG1482	cell wall glycoprotein biosynthetic process
BJD96_RS01740	COG1309	transcriptional regulator
BJD96_RS01755	COG1309	transcriptional regulator
BJD96_RS01765	COG3949	Membrane
BJD96_RS01775	COG0829	nickel cation binding
BJD96_RS01780	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
BJD96_RS01785	COG0830	nickel cation binding
BJD96_RS01790	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
BJD96_RS01795	COG0804	urea catabolic process
BJD96_RS01800	COG0832	Belongs to the urease beta subunit family
BJD96_RS01805	COG0831	urea catabolic process
BJD96_RS01810	COG4413	Urea transporter
BJD96_RS01815	COG0747	negative chemotaxis
BJD96_RS01840	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BJD96_RS01855	COG0561	phosphatase activity
BJD96_RS01865	COG0167	dihydroorotate dehydrogenase activity
BJD96_RS01870	COG3001	Fructosamine kinase
BJD96_RS01935	COG1388	LysM domain
BJD96_RS01940	COG0436	Aminotransferase
BJD96_RS01950	COG2608	mercury ion transmembrane transporter activity
BJD96_RS01955	COG2217	Heavy metal translocating P-type atpase
BJD96_RS01960	COG0659	secondary active sulfate transmembrane transporter activity
BJD96_RS01965	COG1136	(ABC) transporter
BJD96_RS01970	COG0577	efflux transmembrane transporter activity
BJD96_RS01975	COG1028	Short-chain dehydrogenase reductase Sdr
BJD96_RS01990	COG0471	metal ion transport
BJD96_RS01995	COG5505	Protein of unknown function (DUF819)
BJD96_RS02010	COG4336	lyase activity
BJD96_RS02025	COG1012	belongs to the aldehyde dehydrogenase family
BJD96_RS02035	COG2409	Drug exporters of the RND superfamily
BJD96_RS02050	COG1473	amidohydrolase
BJD96_RS02070	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BJD96_RS02075	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BJD96_RS02080	COG3425	synthase
BJD96_RS02085	COG0183	Belongs to the thiolase family
BJD96_RS02095	COG3386	PFAM SMP-30 Gluconolaconase
BJD96_RS02100	COG1757	Na H antiporter
BJD96_RS02105	COG0583	DNA-binding transcription factor activity
BJD96_RS02120	COG0028	Belongs to the TPP enzyme family
BJD96_RS02125	COG1288	antiporter activity
BJD96_RS02140	COG2515	1-aminocyclopropane-1-carboxylate deaminase
BJD96_RS02155	COG0657	acetylesterase activity
BJD96_RS02170	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
BJD96_RS02180	COG2843	Capsule synthesis protein
BJD96_RS02195	COG3949	Membrane
BJD96_RS02215	COG1129	ABC transporter
BJD96_RS02225	COG1609	Transcriptional regulator
BJD96_RS02235	COG1070	Carbohydrate kinase
BJD96_RS02240	COG1063	alcohol dehydrogenase
BJD96_RS02260	COG3764	Sortase (surface protein transpeptidase)
BJD96_RS02265	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
BJD96_RS02270	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BJD96_RS02280	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BJD96_RS02285	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BJD96_RS02290	COG0561	phosphatase activity
BJD96_RS02295	COG0778	Nitroreductase
BJD96_RS02305	COG2514	catechol 2,3-dioxygenase activity
BJD96_RS02310	COG1132	(ABC) transporter
BJD96_RS02315	COG1132	(ABC) transporter
BJD96_RS02330	COG1012	belongs to the aldehyde dehydrogenase family
BJD96_RS02335	COG1846	Transcriptional regulator
BJD96_RS02340	COG0346	lactoylglutathione lyase activity
BJD96_RS02345	COG0346	lactoylglutathione lyase activity
BJD96_RS02350	COG0400	carboxylic ester hydrolase activity
BJD96_RS02355	COG3949	Membrane
BJD96_RS02360	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
BJD96_RS02365	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BJD96_RS02370	COG0586	Pfam SNARE associated Golgi protein
BJD96_RS02375	COG2271	Major facilitator Superfamily
BJD96_RS02385	COG3527	Alpha-acetolactate decarboxylase
BJD96_RS02390	COG1289	transmembrane transporter activity
BJD96_RS02405	COG4876	unkown
BJD96_RS02410	COG2357	RelA SpoT domain protein
BJD96_RS02415	COG1802	Transcriptional regulator
BJD96_RS02420	COG1070	Carbohydrate kinase
BJD96_RS02425	COG2610	gluconate transmembrane transporter activity
BJD96_RS02430	COG1028	Short-chain dehydrogenase reductase Sdr
BJD96_RS02435	COG3949	Membrane
BJD96_RS02445	COG2211	Major facilitator Superfamily
BJD96_RS02450	COG3250	beta-galactosidase activity
BJD96_RS02470	COG2211	Major facilitator Superfamily
BJD96_RS02475	COG1904	glucuronate isomerase
BJD96_RS02480	COG1312	Catalyzes the dehydration of D-mannonate
BJD96_RS02500	COG4221	oxidoreductase activity
BJD96_RS02510	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BJD96_RS02520	COG0107	imidazoleglycerol-phosphate synthase activity
BJD96_RS02525	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
BJD96_RS02530	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
BJD96_RS02535	COG0131	Imidazoleglycerol-phosphate dehydratase
BJD96_RS02540	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BJD96_RS02545	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
BJD96_RS02550	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
BJD96_RS02560	COG3048	D-serine ammonia-lyase activity
BJD96_RS02565	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
BJD96_RS02570	COG0248	Ppx GppA phosphatase
BJD96_RS02575	COG1028	Short-chain dehydrogenase reductase Sdr
BJD96_RS02580	COG1363	Peptidase, m42
BJD96_RS02590	COG0069	glutamate synthase activity
BJD96_RS02600	COG4619	ABC transporter
BJD96_RS02605	COG0390	transport system, permease component
BJD96_RS02610	COG2814	Major facilitator Superfamily
BJD96_RS02615	COG2851	Citrate transporter
BJD96_RS02620	COG0531	amino acid
BJD96_RS02625	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
BJD96_RS02635	COG3246	L-lysine catabolic process to acetate
BJD96_RS02640	COG1250	3-hydroxyacyl-CoA dehydrogenase
BJD96_RS02655	COG1174	glycine betaine transport
BJD96_RS02665	COG1174	glycine betaine transport
BJD96_RS02680	COG4187	Peptidase family M20/M25/M40
BJD96_RS02700	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
BJD96_RS02730	COG2814	Major facilitator Superfamily
BJD96_RS02740	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BJD96_RS02745	COG1388	LysM domain
BJD96_RS02750	COG0588	phosphoglycerate mutase activity
BJD96_RS02760	COG2814	Major facilitator Superfamily
BJD96_RS02785	COG2353	YceI-like domain
BJD96_RS02795	COG1695	Transcriptional regulator
BJD96_RS02820	COG2116	formate transmembrane transporter activity
BJD96_RS02825	COG0454	-acetyltransferase
BJD96_RS02835	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BJD96_RS02835	COG1648	precorrin-2 dehydrogenase activity
BJD96_RS02840	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BJD96_RS02845	COG2146	nitrite reductase [NAD(P)H] activity
BJD96_RS02850	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BJD96_RS02855	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
BJD96_RS02860	COG1140	nitrate reductase beta subunit
BJD96_RS02870	COG2181	nitrate reductase activity
BJD96_RS02880	COG4585	Histidine kinase
BJD96_RS02905	COG1846	Transcriptional regulator
BJD96_RS02945	COG1263	PTS System
BJD96_RS02945	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BJD96_RS02955	COG1283	sodium-dependent phosphate transmembrane transporter activity
BJD96_RS02960	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BJD96_RS02965	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BJD96_RS02970	COG1288	antiporter activity
BJD96_RS02975	COG1349	DNA-binding transcription factor activity
BJD96_RS02980	COG1063	alcohol dehydrogenase
BJD96_RS02985	COG2376	Dihydroxyacetone kinase
BJD96_RS02995	COG0698	ribose 5-phosphate isomerase
BJD96_RS03015	COG0492	ferredoxin-NADP+ reductase activity
BJD96_RS03025	COG2814	Major facilitator Superfamily
BJD96_RS03030	COG0604	alcohol dehydrogenase
BJD96_RS03045	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
BJD96_RS03050	COG1620	l-lactate permease
BJD96_RS03055	COG0438	transferase activity, transferring glycosyl groups
BJD96_RS03065	COG3850	Histidine kinase
BJD96_RS03065	COG5002	protein histidine kinase activity
BJD96_RS03070	COG0745	RESPONSE REGULATOR receiver
BJD96_RS03075	COG0577	efflux transmembrane transporter activity
BJD96_RS03080	COG1136	(ABC) transporter
BJD96_RS03095	COG4640	response to antibiotic
BJD96_RS03110	COG1566	PFAM secretion protein HlyD family protein
BJD96_RS03115	COG2814	Major facilitator Superfamily
BJD96_RS03150	COG1304	FMN binding
BJD96_RS03155	COG0786	glutamate:sodium symporter activity
BJD96_RS03160	COG1695	Transcriptional regulator
BJD96_RS03175	COG1757	Na H antiporter
BJD96_RS03180	COG2094	Belongs to the DNA glycosylase MPG family
BJD96_RS03185	COG3152	Membrane
BJD96_RS03190	COG1069	ribulokinase activity
BJD96_RS03195	COG4152	abc transporter atp-binding protein
BJD96_RS03200	COG1668	transmembrane transport
BJD96_RS03205	COG2017	converts alpha-aldose to the beta-anomer
BJD96_RS03210	COG2258	MOSC domain
BJD96_RS03215	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
BJD96_RS03220	COG1266	CAAX protease self-immunity
BJD96_RS03225	COG0010	Belongs to the arginase family
BJD96_RS03230	COG0583	DNA-binding transcription factor activity
BJD96_RS03235	COG3314	Sporulation integral membrane protein YlbJ
BJD96_RS03240	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
BJD96_RS03245	COG1228	amidohydrolase
BJD96_RS03250	COG0659	secondary active sulfate transmembrane transporter activity
BJD96_RS03255	COG1473	amidohydrolase
BJD96_RS03260	COG1028	Short-chain dehydrogenase reductase Sdr
BJD96_RS03265	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BJD96_RS03285	COG1263	PTS System
BJD96_RS03285	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BJD96_RS03295	COG0385	Bile acid
BJD96_RS03300	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BJD96_RS03325	COG1113	amino acid transport
BJD96_RS03330	COG1785	Belongs to the alkaline phosphatase family
BJD96_RS03340	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BJD96_RS03340	COG1263	PTS System
BJD96_RS03345	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
BJD96_RS03370	COG0483	inositol monophosphate 1-phosphatase activity
BJD96_RS03375	COG1316	TRANSCRIPTIONal
BJD96_RS03380	COG3383	formate dehydrogenase (NAD+) activity
BJD96_RS03405	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BJD96_RS03415	COG2076	Multidrug Resistance protein
BJD96_RS03420	COG3942	CHAP domain
BJD96_RS03435	COG1757	Na H antiporter
BJD96_RS03445	COG3942	CHAP domain
BJD96_RS03470	COG0765	amino acid transport
BJD96_RS03475	COG0765	amino acid transport
BJD96_RS03485	COG1126	abc transporter atp-binding protein
BJD96_RS03490	COG1960	acyl-CoA dehydrogenase activity
BJD96_RS03495	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BJD96_RS03500	COG1268	BioY protein
BJD96_RS03510	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
BJD96_RS03515	COG1609	Transcriptional regulator
BJD96_RS03520	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
BJD96_RS03525	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BJD96_RS03530	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
BJD96_RS03535	COG0725	ABC transporter, periplasmic molybdate-binding protein
BJD96_RS03540	COG4149	molybdate abc transporter
BJD96_RS03545	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
BJD96_RS03555	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BJD96_RS03560	COG0521	Mo-molybdopterin cofactor biosynthetic process
BJD96_RS03565	COG0315	cyclic pyranopterin monophosphate synthase activity
BJD96_RS03590	COG0746	molybdenum cofactor guanylyltransferase activity
BJD96_RS03595	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BJD96_RS03605	COG2814	Major facilitator Superfamily
BJD96_RS03625	COG2348	transferase activity, transferring amino-acyl groups
BJD96_RS03630	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BJD96_RS03660	COG4975	Glucose uptake
BJD96_RS03670	COG0551	DNA topoisomerase type I activity
BJD96_RS03670	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BJD96_RS03675	COG2252	PERMEase
BJD96_RS03685	COG0051	transcription antitermination factor activity, RNA binding
BJD96_RS03690	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
BJD96_RS03695	COG0088	Forms part of the polypeptide exit tunnel
BJD96_RS03700	COG0089	rRNA binding
BJD96_RS03705	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
BJD96_RS03710	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
BJD96_RS03715	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
BJD96_RS03720	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
BJD96_RS03725	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
BJD96_RS03730	COG0255	Belongs to the universal ribosomal protein uL29 family
BJD96_RS03735	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
BJD96_RS03740	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
BJD96_RS03745	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
BJD96_RS03750	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
BJD96_RS03755	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
BJD96_RS03760	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
BJD96_RS03765	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
BJD96_RS03770	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
BJD96_RS03775	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
BJD96_RS03780	COG1841	ribosomal large subunit assembly
BJD96_RS03785	COG0200	Binds to the 23S rRNA
BJD96_RS03790	COG0201	protein transport
BJD96_RS03795	COG0563	adenylate kinase activity
BJD96_RS03805	COG0257	Belongs to the bacterial ribosomal protein bL36 family
BJD96_RS03810	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
BJD96_RS03820	COG0202	RNA polymerase activity
BJD96_RS03825	COG0203	ribosomal protein L17
BJD96_RS03830	COG1122	ATPase activity
BJD96_RS03835	COG1122	ATPase activity
BJD96_RS03845	COG0101	tRNA pseudouridine synthase activity
BJD96_RS03850	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
BJD96_RS03865	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BJD96_RS03870	COG2130	NADP-dependent
BJD96_RS03875	COG0604	alcohol dehydrogenase
BJD96_RS03880	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BJD96_RS03895	COG1302	Protein conserved in bacteria
BJD96_RS03905	COG2814	Major facilitator Superfamily
BJD96_RS03910	COG4264	IucA IucC family
BJD96_RS03915	COG3457	Alanine racemase
BJD96_RS03920	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
BJD96_RS03925	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BJD96_RS03930	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BJD96_RS03935	COG3314	Sporulation integral membrane protein YlbJ
BJD96_RS03940	COG2329	Antibiotic biosynthesis monooxygenase
BJD96_RS03950	COG1988	membrane-bound metal-dependent
BJD96_RS03955	COG4284	Utp--glucose-1-phosphate uridylyltransferase
BJD96_RS03960	COG1272	protein, Hemolysin III
BJD96_RS03975	COG2814	Major facilitator Superfamily
BJD96_RS03980	COG0489	protein tyrosine kinase activity
BJD96_RS04035	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
BJD96_RS04045	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BJD96_RS04050	COG0246	Mannitol dehydrogenase
BJD96_RS04060	COG3711	transcriptional antiterminator
BJD96_RS04065	COG2213	PTS system mannitol-specific
BJD96_RS04080	COG1119	ATPase activity
BJD96_RS04110	COG0702	epimerase
BJD96_RS04115	COG2186	Transcriptional regulator
BJD96_RS04120	COG1482	cell wall glycoprotein biosynthetic process
BJD96_RS04130	COG2855	membrane
BJD96_RS04145	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BJD96_RS04150	COG0783	Belongs to the Dps family
BJD96_RS04155	COG0813	purine-nucleoside phosphorylase activity
BJD96_RS04160	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
BJD96_RS04165	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
BJD96_RS04170	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
BJD96_RS04180	COG1854	S-ribosylhomocysteine lyase activity
BJD96_RS04200	COG5146	pantothenate kinase activity
BJD96_RS04205	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BJD96_RS04210	COG3343	RNA polymerase activity
BJD96_RS04215	COG0504	CTP synthase activity
BJD96_RS04230	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BJD96_RS04240	COG1012	belongs to the aldehyde dehydrogenase family
BJD96_RS04245	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
BJD96_RS04250	COG0254	rRNA binding
BJD96_RS04255	COG1435	thymidine kinase activity
BJD96_RS04260	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
BJD96_RS04265	COG2890	protein-(glutamine-N5) methyltransferase activity
BJD96_RS04270	COG0009	L-threonylcarbamoyladenylate synthase
BJD96_RS04275	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BJD96_RS04280	COG4475	Protein of unknown function (DUF436)
BJD96_RS04285	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
BJD96_RS04290	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
BJD96_RS04295	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
BJD96_RS04305	COG0356	it plays a direct role in the translocation of protons across the membrane
BJD96_RS04310	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BJD96_RS04315	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
BJD96_RS04320	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BJD96_RS04325	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
BJD96_RS04330	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
BJD96_RS04335	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
BJD96_RS04340	COG0355	proton-transporting ATP synthase activity, rotational mechanism
BJD96_RS04350	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BJD96_RS04355	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BJD96_RS04365	COG0629	single-stranded DNA binding
BJD96_RS04370	COG1388	LysM domain
BJD96_RS04375	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
BJD96_RS04385	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
BJD96_RS04390	COG0352	thiamine-phosphate diphosphorylase activity
BJD96_RS04395	COG0706	membrane insertase activity
BJD96_RS04400	COG1418	mRNA catabolic process
BJD96_RS04410	COG1937	Protein conserved in bacteria
BJD96_RS04430	COG0772	Belongs to the SEDS family
BJD96_RS04435	COG1181	Belongs to the D-alanine--D-alanine ligase family
BJD96_RS04440	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BJD96_RS04445	COG0513	Belongs to the DEAD box helicase family
BJD96_RS04455	COG3428	Bacterial PH domain
BJD96_RS04465	COG0736	holo-[acyl-carrier-protein] synthase activity
BJD96_RS04470	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BJD96_RS04480	COG2337	Toxic component of a toxin-antitoxin (TA) module
BJD96_RS04485	COG2208	phosphoserine phosphatase activity
BJD96_RS04500	COG1191	sigma factor activity
BJD96_RS04505	COG2183	response to ionizing radiation
BJD96_RS04510	COG3091	SprT-like family
BJD96_RS04525	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BJD96_RS04595	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BJD96_RS04600	COG0066	3-isopropylmalate dehydratase activity
BJD96_RS04605	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
BJD96_RS04610	COG0473	3-isopropylmalate dehydrogenase activity
BJD96_RS04615	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BJD96_RS04620	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
BJD96_RS04625	COG0440	acetolactate synthase activity
BJD96_RS04630	COG0028	Belongs to the TPP enzyme family
BJD96_RS04640	COG0802	atpase or kinase
BJD96_RS04645	COG1214	PFAM Peptidase M22, glycoprotease
BJD96_RS04650	COG0456	acetyltransferase
BJD96_RS04655	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
BJD96_RS04675	COG0488	(ABC) transporter
BJD96_RS04680	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
BJD96_RS04685	COG2391	methyltransferase activity
BJD96_RS04690	COG0425	Belongs to the sulfur carrier protein TusA family
BJD96_RS04695	COG1609	Transcriptional regulator
BJD96_RS04700	COG1621	beta-fructofuranosidase activity
BJD96_RS04710	COG3279	Response regulator of the LytR AlgR family
BJD96_RS04715	COG3290	protein histidine kinase activity
BJD96_RS04725	COG4512	PFAM Accessory gene regulator B
BJD96_RS04730	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BJD96_RS04750	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
BJD96_RS04755	COG0459	protein refolding
BJD96_RS04780	COG1725	Transcriptional regulator
BJD96_RS04795	COG1131	(ABC) transporter
BJD96_RS04840	COG2706	6-phosphogluconolactonase activity
BJD96_RS04845	COG1012	belongs to the aldehyde dehydrogenase family
BJD96_RS04850	COG1227	inorganic diphosphatase activity
BJD96_RS04855	COG1335	isochorismatase
BJD96_RS04865	COG0471	metal ion transport
BJD96_RS04870	COG0077	Prephenate dehydratase
BJD96_RS04880	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
BJD96_RS04885	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
BJD96_RS04890	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
BJD96_RS04900	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BJD96_RS04905	COG4496	protein, YerC YecD
BJD96_RS04920	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
BJD96_RS04925	COG4851	CamS sex pheromone cAM373 precursor
BJD96_RS04930	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BJD96_RS04935	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BJD96_RS04940	COG0154	amidase activity
BJD96_RS04945	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BJD96_RS04950	COG1597	lipid kinase activity
BJD96_RS04955	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BJD96_RS04965	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BJD96_RS04975	COG1528	Iron-storage protein
BJD96_RS04990	COG4129	membrane
BJD96_RS04995	COG0024	Methionine aminopeptidase
BJD96_RS05010	COG4585	Histidine kinase
BJD96_RS05015	COG2197	response regulator
BJD96_RS05020	COG1295	ribonuclease BN
BJD96_RS05030	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BJD96_RS05035	COG4840	Belongs to the UPF0435 family
BJD96_RS05040	COG2309	aminopeptidase activity
BJD96_RS05045	COG1607	acyl-coa hydrolase
BJD96_RS05060	COG0693	protein deglycase activity
BJD96_RS05065	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BJD96_RS05070	COG2137	regulation of response to DNA damage stimulus
BJD96_RS05080	COG1134	teichoic acid transport
BJD96_RS05090	COG1988	membrane-bound metal-dependent
BJD96_RS05095	COG1194	a g-specific adenine glycosylase
BJD96_RS05100	COG3557	Belongs to the UPF0374 family
BJD96_RS05110	COG4129	membrane
BJD96_RS05115	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
BJD96_RS05120	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BJD96_RS05130	COG0735	belongs to the Fur family
BJD96_RS05290	COG0765	amino acid transport
BJD96_RS05295	COG1126	abc transporter atp-binding protein
BJD96_RS05300	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
BJD96_RS05310	COG0363	glucosamine-6-phosphate deaminase activity
BJD96_RS05325	COG0114	fumarate hydratase activity
BJD96_RS05330	COG0564	pseudouridine synthase activity
BJD96_RS05335	COG4585	Histidine kinase
BJD96_RS05335	COG2203	Gaf domain
BJD96_RS05340	COG2197	response regulator
BJD96_RS05345	COG1301	dicarboxylic acid transport
BJD96_RS05360	COG0788	formyltetrahydrofolate deformylase activity
BJD96_RS05370	COG4399	Belongs to the UPF0754 family
BJD96_RS05375	COG3679	Belongs to the UPF0342 family
BJD96_RS05380	COG0420	3'-5' exonuclease activity
BJD96_RS05385	COG4717	serine-type aminopeptidase activity
BJD96_RS05395	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BJD96_RS05410	COG0537	adenosine 5'-monophosphoramidase activity
BJD96_RS05415	COG1131	(ABC) transporter
BJD96_RS05420	COG4473	ABC transporter
BJD96_RS05430	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
BJD96_RS05435	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
BJD96_RS05440	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
BJD96_RS05445	COG3545	Serine hydrolase
BJD96_RS05510	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
BJD96_RS05520	COG1506	peptidase
BJD96_RS05530	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
BJD96_RS05535	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
BJD96_RS05545	COG0656	L-ascorbic acid biosynthetic process
BJD96_RS05550	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BJD96_RS05555	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BJD96_RS05565	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BJD96_RS05585	COG1595	DNA-templated transcription, initiation
BJD96_RS05610	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BJD96_RS05610	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BJD96_RS05615	COG0307	riboflavin synthase, alpha
BJD96_RS05620	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BJD96_RS05620	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BJD96_RS05625	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
BJD96_RS05635	COG2267	carboxylic ester hydrolase activity
BJD96_RS05640	COG0039	L-malate dehydrogenase activity
BJD96_RS05650	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
BJD96_RS05655	COG1242	4 iron, 4 sulfur cluster binding
BJD96_RS05660	COG2814	Major facilitator Superfamily
BJD96_RS05665	COG0495	leucyl-tRNA aminoacylation
BJD96_RS05675	COG2081	HI0933 family
BJD96_RS05680	COG2244	polysaccharide biosynthetic process
BJD96_RS05685	COG1187	pseudouridine synthase activity
BJD96_RS05695	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BJD96_RS05700	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BJD96_RS05705	COG0510	thiamine kinase activity
BJD96_RS05710	COG0220	tRNA (guanine-N7-)-methyltransferase activity
BJD96_RS05715	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BJD96_RS05720	COG5584	Small secreted protein
BJD96_RS05725	COG1363	Peptidase, m42
BJD96_RS05730	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BJD96_RS05735	COG4848	Belongs to the UPF0354 family
BJD96_RS05740	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BJD96_RS05745	COG1674	ftsk spoiiie
BJD96_RS05750	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BJD96_RS05755	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
BJD96_RS05765	COG1605	Chorismate mutase
BJD96_RS05765	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
BJD96_RS05770	COG1609	Transcriptional regulator
BJD96_RS05775	COG0123	including yeast histone deacetylase and acetoin utilization protein
BJD96_RS05780	COG0454	-acetyltransferase
BJD96_RS05785	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BJD96_RS05800	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BJD96_RS05805	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BJD96_RS05810	COG0204	Acyl-transferase
BJD96_RS05815	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BJD96_RS05815	COG1263	PTS System
BJD96_RS05825	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BJD96_RS05830	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
BJD96_RS05835	COG1764	response to oxidative stress
BJD96_RS05840	COG0584	glycerophosphoryl diester phosphodiesterase
BJD96_RS05850	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
BJD96_RS05860	COG1956	GAF domain-containing protein
BJD96_RS05865	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
BJD96_RS05870	COG1104	cysteine desulfurase activity
BJD96_RS05875	COG0301	tRNA thio-modification
BJD96_RS05880	COG0730	response to heat
BJD96_RS05885	COG0616	signal peptide processing
BJD96_RS05890	COG1714	RDD family
BJD96_RS05895	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
BJD96_RS05905	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
BJD96_RS05915	COG0589	response to stress
BJD96_RS05920	COG0686	Belongs to the AlaDH PNT family
BJD96_RS05925	COG3142	Participates in the control of copper homeostasis
BJD96_RS05930	COG0006	proline dipeptidase activity
BJD96_RS05935	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
BJD96_RS05945	COG4109	DRTGG domain
BJD96_RS05950	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
BJD96_RS05960	COG0281	malic enzyme
BJD96_RS05965	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
BJD96_RS05970	COG0825	malonyl-CoA metabolic process
BJD96_RS05975	COG0205	6-phosphofructokinase activity
BJD96_RS05980	COG0469	pyruvate kinase activity
BJD96_RS05985	COG1113	amino acid transport
BJD96_RS05990	COG0372	Belongs to the citrate synthase family
BJD96_RS05995	COG0538	isocitrate dehydrogenase activity
BJD96_RS06000	COG0745	RESPONSE REGULATOR receiver
BJD96_RS06005	COG5002	protein histidine kinase activity
BJD96_RS06015	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BJD96_RS06015	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BJD96_RS06020	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
BJD96_RS06025	COG0237	dephospho-CoA kinase activity
BJD96_RS06035	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
BJD96_RS06045	COG1484	DNA-dependent DNA replication
BJD96_RS06050	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BJD96_RS06055	COG0833	amino acid
BJD96_RS06060	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
BJD96_RS06065	COG0291	Belongs to the bacterial ribosomal protein bL35 family
BJD96_RS06075	COG4112	unkown
BJD96_RS06085	COG0544	peptidyl-prolyl cis-trans isomerase activity
BJD96_RS06090	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
BJD96_RS06095	COG0218	Necessary for normal cell division and for the maintenance of normal septation
BJD96_RS06100	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
BJD96_RS06105	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BJD96_RS06110	COG0181	hydroxymethylbilane synthase activity
BJD96_RS06120	COG0113	porphobilinogen synthase activity
BJD96_RS06125	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
BJD96_RS06135	COG2818	Glycosylase
BJD96_RS06140	COG0525	valine-tRNA ligase activity
BJD96_RS06145	COG0285	dihydrofolate synthase activity
BJD96_RS06155	COG0656	L-ascorbic acid biosynthetic process
BJD96_RS06180	COG2207	Transcriptional regulator
BJD96_RS06180	COG3708	Transcriptional regulator
BJD96_RS06190	COG2003	Belongs to the UPF0758 family
BJD96_RS06220	COG0261	This protein binds to 23S rRNA in the presence of protein L20
BJD96_RS06225	COG2868	ribosomal protein
BJD96_RS06230	COG0211	Belongs to the bacterial ribosomal protein bL27 family
BJD96_RS06235	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
BJD96_RS06240	COG4492	Belongs to the UPF0735 family
BJD96_RS06245	COG0632	four-way junction helicase activity
BJD96_RS06250	COG2255	four-way junction helicase activity
BJD96_RS06255	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
BJD96_RS06260	COG0343	queuine tRNA-ribosyltransferase activity
BJD96_RS06265	COG1862	Preprotein translocase
BJD96_RS06270	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BJD96_RS06270	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BJD96_RS06275	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BJD96_RS06275	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
BJD96_RS06290	COG1490	D-aminoacyl-tRNA deacylase activity
BJD96_RS06295	COG0860	N-Acetylmuramoyl-L-alanine amidase
BJD96_RS06300	COG0124	histidyl-tRNA synthetase
BJD96_RS06305	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
BJD96_RS06315	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
BJD96_RS06320	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BJD96_RS06325	COG1959	2 iron, 2 sulfur cluster binding
BJD96_RS06335	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BJD96_RS06340	COG0488	(ABC) transporter
BJD96_RS06345	COG1104	cysteine desulfurase activity
BJD96_RS06350	COG0482	sulfurtransferase activity
BJD96_RS06360	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BJD96_RS06365	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BJD96_RS06370	COG4472	Bacterial protein of unknown function (DUF965)
BJD96_RS06375	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
BJD96_RS06380	COG3906	Belongs to the UPF0473 family
BJD96_RS06390	COG0826	peptidase U32
BJD96_RS06395	COG0826	peptidase U32
BJD96_RS06400	COG0572	uridine kinase
BJD96_RS06410	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
BJD96_RS06415	COG1984	allophanate hydrolase subunit 2
BJD96_RS06425	COG0439	Biotin carboxylase
BJD96_RS06430	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
BJD96_RS06435	COG1914	H( )-stimulated, divalent metal cation uptake system
BJD96_RS06440	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BJD96_RS06445	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
BJD96_RS06450	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
BJD96_RS06455	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BJD96_RS06460	COG1534	Rna-binding protein
BJD96_RS06465	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
BJD96_RS06470	COG1713	HD superfamily hydrolase involved in NAD metabolism
BJD96_RS06475	COG0799	negative regulation of ribosome biogenesis
BJD96_RS06485	COG1555	photosystem II stabilization
BJD96_RS06490	COG2131	deaminase
BJD96_RS06495	COG2333	competence protein COMEC
BJD96_RS06495	COG0658	competence protein
BJD96_RS06500	COG1466	dna polymerase III delta subunit
BJD96_RS06505	COG0268	Binds directly to 16S ribosomal RNA
BJD96_RS06510	COG0481	GTPase activity
BJD96_RS06515	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BJD96_RS06520	COG1420	regulation of RNA biosynthetic process
BJD96_RS06525	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
BJD96_RS06530	COG0443	Heat shock 70 kDa protein
BJD96_RS06535	COG0484	heat shock protein binding
BJD96_RS06540	COG2264	protein methyltransferase activity
BJD96_RS06545	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BJD96_RS06550	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BJD96_RS06555	COG0828	Belongs to the bacterial ribosomal protein bS21 family
BJD96_RS06560	COG1030	water channel activity
BJD96_RS06565	COG4864	UPF0365 protein
BJD96_RS06575	COG1702	phosphate starvation-inducible protein PhoH
BJD96_RS06580	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
BJD96_RS06595	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
BJD96_RS06600	COG1381	Involved in DNA repair and RecF pathway recombination
BJD96_RS06605	COG0423	glycine-tRNA ligase activity
BJD96_RS06610	COG0517	IMP dehydrogenase activity
BJD96_RS06615	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
BJD96_RS06625	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BJD96_RS06630	COG2384	SAM-dependent methyltransferase
BJD96_RS06635	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BJD96_RS06640	COG0513	Belongs to the DEAD box helicase family
BJD96_RS06645	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
BJD96_RS06650	COG1121	(ABC) transporter
BJD96_RS06655	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BJD96_RS06665	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BJD96_RS06670	COG0768	penicillin binding
BJD96_RS06675	COG0267	Belongs to the bacterial ribosomal protein bL33 family
BJD96_RS06680	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BJD96_RS06685	COG0705	Rhomboid family
BJD96_RS06685	COG0457	Tetratricopeptide repeat
BJD96_RS06690	COG4483	Protein conserved in bacteria
BJD96_RS06695	COG1940	carbohydrate kinase activity
BJD96_RS06700	COG0011	TIGRFAM Protein of
BJD96_RS06705	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BJD96_RS06710	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BJD96_RS06715	COG1459	type II secretion system
BJD96_RS06720	COG4537	Required for transformation and DNA binding
BJD96_RS06745	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
BJD96_RS06750	COG0404	The glycine cleavage system catalyzes the degradation of glycine
BJD96_RS06755	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BJD96_RS06760	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BJD96_RS06765	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BJD96_RS06770	COG0095	Lipoate-protein ligase
BJD96_RS06785	COG0006	proline dipeptidase activity
BJD96_RS06790	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
BJD96_RS06795	COG0511	ligase activity, forming carbon-carbon bonds
BJD96_RS06800	COG0439	Biotin carboxylase
BJD96_RS06805	COG1302	Protein conserved in bacteria
BJD96_RS06810	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BJD96_RS06815	COG1570	exodeoxyribonuclease VII activity
BJD96_RS06830	COG1438	arginine binding
BJD96_RS06835	COG0497	DNA recombination
BJD96_RS06845	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BJD96_RS06850	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BJD96_RS06855	COG0022	dehydrogenase e1 component
BJD96_RS06860	COG0508	dehydrogenase complex catalyzes the overall conversion of
BJD96_RS06870	COG4129	membrane
BJD96_RS06875	COG2195	Cleaves the N-terminal amino acid of tripeptides
BJD96_RS06885	COG0366	Alpha amylase catalytic
BJD96_RS06895	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BJD96_RS06900	COG1234	tRNA 3'-trailer cleavage
BJD96_RS06905	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BJD96_RS06915	COG0667	Aldo Keto reductase
BJD96_RS06920	COG0494	nUDIX hydrolase
BJD96_RS06925	COG0735	belongs to the Fur family
BJD96_RS06930	COG4974	Belongs to the 'phage' integrase family
BJD96_RS06940	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
BJD96_RS06945	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
BJD96_RS06950	COG1187	pseudouridine synthase activity
BJD96_RS06955	COG0745	RESPONSE REGULATOR receiver
BJD96_RS06970	COG1141	Ferredoxin
BJD96_RS06980	COG0514	ATP-dependent DNA helicase (RecQ)
BJD96_RS06990	COG0492	ferredoxin-NADP+ reductase activity
BJD96_RS06995	COG0252	asparaginase activity
BJD96_RS07000	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
BJD96_RS07005	COG0539	negative regulation of cytoplasmic translation
BJD96_RS07010	COG1160	GTP binding
BJD96_RS07015	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
BJD96_RS07030	COG2226	methyltransferase
BJD96_RS07035	COG0142	geranyltranstransferase activity
BJD96_RS07040	COG0105	UTP biosynthetic process
BJD96_RS07045	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
BJD96_RS07050	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
BJD96_RS07055	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
BJD96_RS07065	COG5582	Belongs to the UPF0302 family
BJD96_RS07070	COG4347	Protein of unknown function (DUF1405)
BJD96_RS07075	COG2738	Putative neutral zinc metallopeptidase
BJD96_RS07080	COG1694	Mazg nucleotide pyrophosphohydrolase
BJD96_RS07085	COG0438	transferase activity, transferring glycosyl groups
BJD96_RS07090	COG0617	tRNA 3'-terminal CCA addition
BJD96_RS07100	COG1199	ATP-dependent helicase activity
BJD96_RS07100	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BJD96_RS07105	COG0017	Asparaginyl-tRNA synthetase
BJD96_RS07110	COG3935	DnaD domain protein
BJD96_RS07115	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BJD96_RS07125	COG4499	WXG100 protein secretion system (Wss), protein YukC
BJD96_RS07125	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BJD96_RS07130	COG3331	DNA recombination
BJD96_RS07140	COG4474	Belongs to the UPF0398 family
BJD96_RS07145	COG3599	regulation of cell shape
BJD96_RS07155	COG0116	Belongs to the methyltransferase superfamily
BJD96_RS07160	COG2962	Rard protein
BJD96_RS07170	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BJD96_RS07175	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BJD96_RS07180	COG0328	RNA-DNA hybrid ribonuclease activity
BJD96_RS07190	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
BJD96_RS07200	COG1413	lyase activity
BJD96_RS07205	COG1413	lyase activity
BJD96_RS07215	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
BJD96_RS07235	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BJD96_RS07245	COG4479	Belongs to the UPF0346 family
BJD96_RS07250	COG0793	Belongs to the peptidase S41A family
BJD96_RS07260	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BJD96_RS07265	COG0671	phosphoesterase, PA-phosphatase related
BJD96_RS07270	COG0745	RESPONSE REGULATOR receiver
BJD96_RS07275	COG5002	protein histidine kinase activity
BJD96_RS07280	COG0567	Dehydrogenase, E1 component
BJD96_RS07285	COG0508	dehydrogenase complex catalyzes the overall conversion of
BJD96_RS07290	COG1396	sequence-specific DNA binding
BJD96_RS07295	COG4977	sequence-specific DNA binding
BJD96_RS07315	COG0673	inositol 2-dehydrogenase activity
BJD96_RS07335	COG0714	Associated with various cellular activities
BJD96_RS07340	COG4548	von Willebrand factor, type A
BJD96_RS07345	COG1114	Component of the transport system for branched-chain amino acids
BJD96_RS07350	COG3853	Toxic anion resistance protein (TelA)
BJD96_RS07360	COG1254	Belongs to the acylphosphatase family
BJD96_RS07370	COG1278	Cold shock
BJD96_RS07385	COG1473	amidohydrolase
BJD96_RS07395	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
BJD96_RS07400	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BJD96_RS07405	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BJD96_RS07410	COG0527	aspartate kinase activity
BJD96_RS07420	COG0488	(ABC) transporter
BJD96_RS07425	COG2996	Protein conserved in bacteria
BJD96_RS07430	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BJD96_RS07435	COG0573	inorganic phosphate transmembrane transporter activity
BJD96_RS07440	COG0581	inorganic phosphate transmembrane transporter activity
BJD96_RS07445	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BJD96_RS07450	COG0704	Plays a role in the regulation of phosphate uptake
BJD96_RS07455	COG1164	Oligoendopeptidase f
BJD96_RS07470	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BJD96_RS07475	COG0450	alkyl hydroperoxide reductase
BJD96_RS07485	COG2124	cytochrome p450
BJD96_RS07495	COG1012	belongs to the aldehyde dehydrogenase family
BJD96_RS07500	COG0667	Aldo Keto reductase
BJD96_RS07530	COG1063	alcohol dehydrogenase
BJD96_RS07540	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BJD96_RS07550	COG2348	transferase activity, transferring amino-acyl groups
BJD96_RS07565	COG0159	tryptophan synthase activity
BJD96_RS07570	COG0133	tryptophan synthase activity
BJD96_RS07580	COG0134	indole-3-glycerol-phosphate synthase activity
BJD96_RS07585	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BJD96_RS07590	COG0512	Glutamine amidotransferase of anthranilate synthase
BJD96_RS07595	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BJD96_RS07610	COG0287	Prephenate dehydrogenase
BJD96_RS07615	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BJD96_RS07620	COG1942	4-Oxalocrotonate Tautomerase
BJD96_RS07635	COG1879	ABC-type sugar transport system periplasmic component
BJD96_RS07640	COG1172	Belongs to the binding-protein-dependent transport system permease family
BJD96_RS07645	COG1129	ABC transporter
BJD96_RS07650	COG1869	D-ribose catabolic process
BJD96_RS07655	COG1609	Transcriptional regulator
BJD96_RS07665	COG0392	lysyltransferase activity
BJD96_RS07665	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
BJD96_RS07670	COG0628	permease
BJD96_RS07675	COG1115	amino acid carrier protein
BJD96_RS07680	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BJD96_RS07690	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
BJD96_RS07695	COG4841	protein insertion into membrane
BJD96_RS07700	COG0824	Thioesterase
BJD96_RS07705	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
BJD96_RS07710	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BJD96_RS07715	COG1970	mechanosensitive ion channel activity
BJD96_RS07720	COG0419	ATPase involved in DNA repair
BJD96_RS07725	COG0420	3'-5' exonuclease activity
BJD96_RS07730	COG4846	Membrane protein involved in cytochrome C biogenesis
BJD96_RS07785	COG0739	heme binding
BJD96_RS07875	COG3331	DNA recombination
BJD96_RS07955	COG1484	DNA-dependent DNA replication
BJD96_RS07975	COG3723	Recombinational DNA repair protein, rece pathway
BJD96_RS07980	COG5377	YqaJ viral recombinase family
BJD96_RS08000	COG3422	double-strand break repair
BJD96_RS08030	COG2856	Zn peptidase
BJD96_RS08035	COG0582	viral genome integration into host DNA
BJD96_RS08040	COG3763	UPF0154 protein
BJD96_RS08060	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
BJD96_RS08070	COG0516	GMP reductase activity
BJD96_RS08075	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
BJD96_RS08080	COG0267	Belongs to the bacterial ribosomal protein bL33 family
BJD96_RS08090	COG0753	catalase activity
BJD96_RS08095	COG0833	amino acid
BJD96_RS08105	COG1522	sequence-specific DNA binding
BJD96_RS08110	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
BJD96_RS08130	COG0561	phosphatase activity
BJD96_RS08135	COG0083	homoserine kinase activity
BJD96_RS08140	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
BJD96_RS08145	COG0460	homoserine dehydrogenase
BJD96_RS08150	COG0527	aspartate kinase activity
BJD96_RS08170	COG1525	nuclease
BJD96_RS08205	COG0174	glutamine synthetase
BJD96_RS08210	COG0789	Transcriptional regulator
BJD96_RS08215	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
BJD96_RS08220	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BJD96_RS08225	COG0386	Belongs to the glutathione peroxidase family
BJD96_RS08230	COG1923	regulation of RNA biosynthetic process
BJD96_RS08235	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
BJD96_RS08245	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
BJD96_RS08250	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
BJD96_RS08255	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BJD96_RS08260	COG1619	proteins homologs of microcin C7 resistance protein MccF
BJD96_RS08270	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
BJD96_RS08275	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
BJD96_RS08285	COG4550	Control of competence regulator ComK, YlbF/YmcA
BJD96_RS08290	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BJD96_RS08300	COG0492	ferredoxin-NADP+ reductase activity
BJD96_RS08305	COG1959	2 iron, 2 sulfur cluster binding
BJD96_RS08315	COG1013	pyruvate-flavodoxin oxidoreductase activity
BJD96_RS08320	COG0674	pyruvate-flavodoxin oxidoreductase activity
BJD96_RS08320	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
BJD96_RS08325	COG1692	metallophosphoesterase
BJD96_RS08335	COG1418	mRNA catabolic process
BJD96_RS08340	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
BJD96_RS08345	COG1546	Belongs to the CinA family
BJD96_RS08345	COG1058	Belongs to the CinA family
BJD96_RS08365	COG0300	oxidoreductase activity
BJD96_RS08370	COG0612	Peptidase, M16
BJD96_RS08375	COG0612	Peptidase, M16
BJD96_RS08390	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BJD96_RS08395	COG1185	polyribonucleotide nucleotidyltransferase activity
BJD96_RS08400	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
BJD96_RS08405	COG0196	riboflavin kinase activity
BJD96_RS08410	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
BJD96_RS08415	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
BJD96_RS08430	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
BJD96_RS08435	COG1358	cellular component organization or biogenesis
BJD96_RS08440	COG2740	Nucleic-acid-binding protein implicated in transcription termination
BJD96_RS08445	COG0195	Participates in both transcription termination and antitermination
BJD96_RS08450	COG0779	Required for maturation of 30S ribosomal subunits
BJD96_RS08455	COG2176	DNA-directed DNA polymerase activity
BJD96_RS08460	COG0442	prolyl-tRNA aminoacylation
BJD96_RS08470	COG4589	Belongs to the CDS family
BJD96_RS08475	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
BJD96_RS08480	COG0233	cytoplasmic translational termination
BJD96_RS08485	COG0528	UMP kinase activity
BJD96_RS08490	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
BJD96_RS08495	COG0052	Belongs to the universal ribosomal protein uS2 family
BJD96_RS08500	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
BJD96_RS08505	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
BJD96_RS08510	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
BJD96_RS08515	COG4974	Belongs to the 'phage' integrase family
BJD96_RS08520	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
BJD96_RS08525	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BJD96_RS08530	COG0758	DNA mediated transformation
BJD96_RS08540	COG0045	succinate-CoA ligase (ADP-forming) activity
BJD96_RS08545	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BJD96_RS08555	COG4485	Bacterial membrane protein, YfhO
BJD96_RS08565	COG0335	large ribosomal subunit rRNA binding
BJD96_RS08570	COG0336	Belongs to the RNA methyltransferase TrmD family
BJD96_RS08575	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
BJD96_RS08580	COG0228	four-way junction DNA binding
BJD96_RS08585	COG1028	Short-chain dehydrogenase reductase Sdr
BJD96_RS08600	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BJD96_RS08605	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
BJD96_RS08610	COG0552	protein localization to endoplasmic reticulum
BJD96_RS08615	COG1196	nuclear chromosome segregation
BJD96_RS08620	COG0571	ribonuclease III activity
BJD96_RS08625	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BJD96_RS08630	COG1028	Short-chain dehydrogenase reductase Sdr
BJD96_RS08640	COG0416	fatty acid biosynthetic process
BJD96_RS08645	COG1349	DNA-binding transcription factor activity
BJD96_RS08660	COG1760	l-serine dehydratase
BJD96_RS08665	COG1760	l-serine dehydratase
BJD96_RS08670	COG1461	Dihydroxyacetone kinase
BJD96_RS08675	COG1302	Protein conserved in bacteria
BJD96_RS08680	COG0227	Belongs to the bacterial ribosomal protein bL28 family
BJD96_RS08685	COG1564	THIamine pyrophosphokinase
BJD96_RS08690	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BJD96_RS08695	COG1162	GTPase activity
BJD96_RS08705	COG0631	protein serine/threonine phosphatase activity
BJD96_RS08710	COG0820	rRNA (adenine-C2-)-methyltransferase activity
BJD96_RS08715	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BJD96_RS08715	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BJD96_RS08720	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BJD96_RS08725	COG0242	peptide deformylase activity
BJD96_RS08740	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
BJD96_RS08745	COG1473	amidohydrolase
BJD96_RS08770	COG1028	Short-chain dehydrogenase reductase Sdr
BJD96_RS08790	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BJD96_RS08800	COG5632	N-Acetylmuramoyl-L-alanine amidase
BJD96_RS08800	COG1388	LysM domain
BJD96_RS08825	COG5434	Belongs to the glycosyl hydrolase 28 family
BJD96_RS08825	COG4632	Exopolysaccharide biosynthesis protein
BJD96_RS08895	COG0740	serine-type endopeptidase activity
BJD96_RS09015	COG1484	DNA-dependent DNA replication
BJD96_RS09105	COG0582	viral genome integration into host DNA
BJD96_RS09110	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BJD96_RS09115	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BJD96_RS09120	COG1758	RNA polymerase activity
BJD96_RS09125	COG0194	GDP metabolic process
BJD96_RS09140	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BJD96_RS09150	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
BJD96_RS09155	COG0284	orotidine-5'-phosphate decarboxylase activity
BJD96_RS09160	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
BJD96_RS09165	COG0505	Belongs to the CarA family
BJD96_RS09175	COG0540	Belongs to the ATCase OTCase family
BJD96_RS09180	COG2233	PERMEase
BJD96_RS09185	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
BJD96_RS09190	COG0564	pseudouridine synthase activity
BJD96_RS09195	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
BJD96_RS09205	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
BJD96_RS09210	COG3599	regulation of cell shape
BJD96_RS09220	COG0762	integral membrane protein
BJD96_RS09225	COG1799	cell septum assembly
BJD96_RS09230	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
BJD96_RS09235	COG1496	oxidoreductase activity
BJD96_RS09240	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BJD96_RS09245	COG0849	cell division
BJD96_RS09250	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
BJD96_RS09255	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
BJD96_RS09260	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BJD96_RS09265	COG0768	penicillin binding
BJD96_RS09270	COG4839	cell division protein FtsL
BJD96_RS09275	COG0275	rRNA processing
BJD96_RS09280	COG2001	Belongs to the MraZ family
BJD96_RS09285	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
BJD96_RS09290	COG0454	-acetyltransferase
BJD96_RS09295	COG1011	Hydrolase
BJD96_RS09325	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BJD96_RS09350	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
BJD96_RS09355	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BJD96_RS09360	COG1053	succinate dehydrogenase
BJD96_RS09365	COG2009	succinate dehydrogenase
BJD96_RS09370	COG0322	excinuclease ABC activity
BJD96_RS09375	COG3118	belongs to the thioredoxin family
BJD96_RS09380	COG1193	negative regulation of DNA recombination
BJD96_RS09385	COG1796	DNA polymerase
BJD96_RS09385	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
BJD96_RS09395	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
BJD96_RS09400	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BJD96_RS09405	COG0072	phenylalanine-tRNA ligase activity
BJD96_RS09410	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
BJD96_RS09415	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BJD96_RS09425	COG0333	Belongs to the bacterial ribosomal protein bL32 family
BJD96_RS09435	COG1323	Belongs to the UPF0348 family
BJD96_RS09445	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
BJD96_RS09450	COG0742	ribosomal rna small subunit methyltransferase
BJD96_RS09460	COG4471	UPF0298 protein
BJD96_RS09465	COG0584	glycerophosphoryl diester phosphodiesterase
BJD96_RS09470	COG3679	Belongs to the UPF0342 family
BJD96_RS09485	COG0109	protoheme IX farnesyltransferase activity
BJD96_RS09490	COG1612	heme a metabolic process
BJD96_RS09500	COG0772	Belongs to the SEDS family
BJD96_RS09505	COG4838	Belongs to the UPF0358 family
BJD96_RS09510	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BJD96_RS09515	COG4896	Protein conserved in bacteria
BJD96_RS09520	COG1217	gtp-binding protein TYPA
BJD96_RS09530	COG0483	inositol monophosphate 1-phosphatase activity
BJD96_RS09535	COG4493	Belongs to the UPF0637 family
BJD96_RS09545	COG1914	H( )-stimulated, divalent metal cation uptake system
BJD96_RS09565	COG1176	ABC-type spermidine putrescine transport system, permease component I
BJD96_RS09575	COG4476	Belongs to the UPF0223 family
BJD96_RS09595	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BJD96_RS09605	COG0242	peptide deformylase activity
BJD96_RS09615	COG5503	Protein of unknown function (DUF1447)
BJD96_RS09620	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BJD96_RS09625	COG0569	domain protein
BJD96_RS09630	COG1294	oxidase, subunit
BJD96_RS09635	COG1271	oxidase subunit
BJD96_RS09645	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BJD96_RS09650	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BJD96_RS09660	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
BJD96_RS09675	COG4172	Belongs to the ABC transporter superfamily
BJD96_RS09680	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
BJD96_RS09685	COG0151	Belongs to the GarS family
BJD96_RS09690	COG0138	bifunctional purine biosynthesis protein purh
BJD96_RS09700	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
BJD96_RS09710	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BJD96_RS09715	COG0047	phosphoribosylformylglycinamidine synthase activity
BJD96_RS09720	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BJD96_RS09725	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
BJD96_RS09730	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
BJD96_RS09735	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
BJD96_RS09740	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
BJD96_RS09750	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BJD96_RS09755	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BJD96_RS09760	COG1845	cytochrome c oxidase, subunit III
BJD96_RS09765	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
BJD96_RS09780	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BJD96_RS09785	COG1316	TRANSCRIPTIONal
BJD96_RS09810	COG3594	Acyltransferase
BJD96_RS09815	COG0436	Aminotransferase
BJD96_RS09825	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
BJD96_RS09830	COG2267	carboxylic ester hydrolase activity
BJD96_RS09835	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
BJD96_RS09840	COG1169	isochorismate synthase
BJD96_RS09845	COG1575	Belongs to the MenA family. Type 1 subfamily
BJD96_RS09855	COG2314	TM2 domain
BJD96_RS09880	COG4903	ComK protein
BJD96_RS09895	COG4873	Protein conserved in bacteria
BJD96_RS09905	COG0737	Belongs to the 5'-nucleotidase family
BJD96_RS09910	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BJD96_RS09915	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BJD96_RS09920	COG0861	Integral membrane protein TerC family
BJD96_RS09925	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
BJD96_RS09935	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BJD96_RS09940	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BJD96_RS09945	COG2814	Major facilitator Superfamily
BJD96_RS09950	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
BJD96_RS09955	COG2382	esterase
BJD96_RS09960	COG1115	amino acid carrier protein
BJD96_RS09965	COG0628	permease
BJD96_RS09975	COG0475	glutathione-regulated potassium exporter activity
BJD96_RS09975	COG0569	domain protein
BJD96_RS09980	COG2239	Acts as a magnesium transporter
BJD96_RS09985	COG0564	pseudouridine synthase activity
BJD96_RS09990	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BJD96_RS09995	COG2357	RelA SpoT domain protein
BJD96_RS10005	COG4116	CYTH
BJD96_RS10010	COG2346	COG2346, Truncated hemoglobins
BJD96_RS10015	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
BJD96_RS10020	COG1164	Oligoendopeptidase f
BJD96_RS10030	COG4862	establishment of competence for transformation
BJD96_RS10035	COG1393	Belongs to the ArsC family
BJD96_RS10040	COG0180	Tryptophanyl-tRNA synthetase
BJD96_RS10045	COG4166	transmembrane transport
BJD96_RS10050	COG4608	Belongs to the ABC transporter superfamily
BJD96_RS10055	COG0444	Belongs to the ABC transporter superfamily
BJD96_RS10060	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BJD96_RS10065	COG0601	transmembrane transport
BJD96_RS10085	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BJD96_RS10125	COG0561	phosphatase activity
BJD96_RS10130	COG0446	pyridine nucleotide-disulphide oxidoreductase
BJD96_RS10150	COG0179	Fumarylacetoacetate (FAA) hydrolase
BJD96_RS10155	COG2311	Membrane
BJD96_RS10160	COG1074	ATP-dependent DNA helicase activity
BJD96_RS10165	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
BJD96_RS10180	COG0398	Pfam SNARE associated Golgi protein
BJD96_RS10185	COG0166	Belongs to the GPI family
BJD96_RS10190	COG0137	argininosuccinate synthase activity
BJD96_RS10195	COG0165	Argininosuccinate lyase
BJD96_RS10200	COG0584	glycerophosphoryl diester phosphodiesterase
BJD96_RS10210	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BJD96_RS10215	COG1902	pentaerythritol trinitrate reductase activity
BJD96_RS10220	COG1098	S1 RNA binding domain
BJD96_RS10225	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BJD96_RS10235	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BJD96_RS10235	COG2111	Na H antiporter
BJD96_RS10240	COG2111	Na H antiporter
BJD96_RS10245	COG1006	Multisubunit Na H antiporter MnhC subunit
BJD96_RS10250	COG0651	ATP synthesis coupled electron transport
BJD96_RS10255	COG1863	multisubunit Na H antiporter MnhE subunit
BJD96_RS10260	COG2212	antiporter activity
BJD96_RS10265	COG1320	monovalent cation:proton antiporter activity
BJD96_RS10275	COG2050	protein possibly involved in aromatic compounds catabolism
BJD96_RS10280	COG2056	Na+-H+ antiporter family
BJD96_RS10285	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
BJD96_RS10290	COG1252	NADH dehydrogenase
BJD96_RS10295	COG0316	Belongs to the HesB IscA family
BJD96_RS10300	COG4844	belongs to the
BJD96_RS10305	COG1252	NADH dehydrogenase
BJD96_RS10310	COG4837	Protein of unknown function (DUF1462)
BJD96_RS10315	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
BJD96_RS10320	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
BJD96_RS10325	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BJD96_RS10330	COG1696	Membrane protein involved in D-alanine export
BJD96_RS10335	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BJD96_RS10345	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BJD96_RS10350	COG0647	UMP catabolic process
BJD96_RS10355	COG2445	Protein of unknown function DUF86
BJD96_RS10365	COG4470	Protein conserved in bacteria
BJD96_RS10370	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
BJD96_RS10375	COG0737	Belongs to the 5'-nucleotidase family
BJD96_RS10380	COG0730	response to heat
BJD96_RS10385	COG1801	Protein of unknown function DUF72
BJD96_RS10390	COG2070	2-Nitropropane dioxygenase
BJD96_RS10395	COG1253	flavin adenine dinucleotide binding
BJD96_RS10450	COG4632	Exopolysaccharide biosynthesis protein
BJD96_RS10450	COG5434	Belongs to the glycosyl hydrolase 28 family
BJD96_RS10520	COG0740	serine-type endopeptidase activity
BJD96_RS10640	COG1484	DNA-dependent DNA replication
BJD96_RS10710	COG4974	Belongs to the 'phage' integrase family
BJD96_RS10715	COG0719	Fe-S assembly protein
BJD96_RS10720	COG0822	iron-sulfur transferase activity
BJD96_RS10730	COG0719	Fe-S assembly protein
BJD96_RS10735	COG0396	ATPase activity
BJD96_RS10745	COG1253	flavin adenine dinucleotide binding
BJD96_RS10750	COG1464	Belongs to the NlpA lipoprotein family
BJD96_RS10755	COG2011	ABC-type metal ion transport system permease component
BJD96_RS10760	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BJD96_RS10765	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BJD96_RS10770	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
BJD96_RS10775	COG0509	glycine decarboxylation via glycine cleavage system
BJD96_RS10780	COG1393	Belongs to the ArsC family
BJD96_RS10785	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BJD96_RS10795	COG0710	3-dehydroquinate dehydratase activity
BJD96_RS10800	COG1764	response to oxidative stress
BJD96_RS10825	COG2314	TM2 domain
BJD96_RS10865	COG0346	lactoylglutathione lyase activity
BJD96_RS10900	COG1288	antiporter activity
BJD96_RS10905	COG1028	Short-chain dehydrogenase reductase Sdr
BJD96_RS10920	COG0584	glycerophosphoryl diester phosphodiesterase
BJD96_RS10940	COG1051	belongs to the nudix hydrolase family
BJD96_RS10975	COG1525	nuclease
BJD96_RS11080	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
BJD96_RS11085	COG0557	exoribonuclease II activity
BJD96_RS11090	COG1647	Serine aminopeptidase, S33
BJD96_RS11095	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BJD96_RS11105	COG0148	phosphopyruvate hydratase activity
BJD96_RS11110	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
BJD96_RS11115	COG0149	triose-phosphate isomerase activity
BJD96_RS11120	COG0126	phosphoglycerate kinase activity
BJD96_RS11125	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BJD96_RS11150	COG1090	epimerase
BJD96_RS11155	COG0740	serine-type endopeptidase activity
BJD96_RS11170	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BJD96_RS11175	COG1481	regulation of sporulation
BJD96_RS11180	COG0391	Required for morphogenesis under gluconeogenic growth conditions
BJD96_RS11185	COG1660	Displays ATPase and GTPase activities
BJD96_RS11190	COG0492	ferredoxin-NADP+ reductase activity
BJD96_RS11200	COG0110	maltose O-acetyltransferase activity
BJD96_RS11205	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
BJD96_RS11210	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
BJD96_RS11215	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BJD96_RS11220	COG0556	nucleotide-excision repair
BJD96_RS11235	COG1388	LysM domain
BJD96_RS11235	COG3942	CHAP domain
BJD96_RS11245	COG0653	protein targeting
BJD96_RS11250	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
BJD96_RS11255	COG1040	competence protein
BJD96_RS11260	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
BJD96_RS11270	COG1739	Uncharacterized protein family UPF0029
BJD96_RS11275	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BJD96_RS11280	COG2199	diguanylate cyclase activity
BJD96_RS11295	COG2195	Cleaves the N-terminal amino acid of tripeptides
BJD96_RS11300	COG1929	Belongs to the glycerate kinase type-1 family
BJD96_RS11320	COG0812	UDP-N-acetylmuramate dehydrogenase activity
BJD96_RS11335	COG4607	ABC-type enterochelin transport system periplasmic component
BJD96_RS11340	COG4604	ABC transporter, ATP-binding protein
BJD96_RS11345	COG4605	iron ion homeostasis
BJD96_RS11350	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BJD96_RS11355	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BJD96_RS11360	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BJD96_RS11365	COG1780	Probably involved in ribonucleotide reductase function
BJD96_RS11375	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
BJD96_RS11380	COG3104	oligopeptide transport
BJD96_RS11385	COG3104	oligopeptide transport
BJD96_RS11390	COG1597	lipid kinase activity
BJD96_RS11400	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BJD96_RS11405	COG1174	glycine betaine transport
BJD96_RS11415	COG0514	ATP-dependent DNA helicase (RecQ)
BJD96_RS11420	COG0488	(ABC) transporter
BJD96_RS11430	COG1368	sulfuric ester hydrolase activity
BJD96_RS11460	COG0512	Glutamine amidotransferase of anthranilate synthase
BJD96_RS11465	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
BJD96_RS11470	COG0720	synthase
BJD96_RS11475	COG0602	queuosine metabolic process
BJD96_RS11490	COG0463	Glycosyl transferase, family 2
BJD96_RS11495	COG0656	L-ascorbic acid biosynthetic process
BJD96_RS11500	COG1253	flavin adenine dinucleotide binding
BJD96_RS11505	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BJD96_RS11510	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BJD96_RS11510	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BJD96_RS11510	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BJD96_RS11515	COG1105	Belongs to the carbohydrate kinase PfkB family
BJD96_RS11520	COG1349	DNA-binding transcription factor activity
BJD96_RS11525	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BJD96_RS11530	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BJD96_RS11560	COG0039	L-malate dehydrogenase activity
BJD96_RS11565	COG0586	Pfam SNARE associated Golgi protein
BJD96_RS11575	COG4989	oxidoreductase activity
BJD96_RS11590	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
BJD96_RS11595	COG4988	ABC transporter
BJD96_RS11600	COG1968	undecaprenyl-diphosphatase activity
BJD96_RS11610	COG1671	Belongs to the UPF0178 family
BJD96_RS11615	COG1611	Belongs to the LOG family
BJD96_RS11620	COG1279	arginine transmembrane transporter activity
BJD96_RS11625	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BJD96_RS11655	COG2814	Major facilitator Superfamily
BJD96_RS11660	COG2839	Protein conserved in bacteria
BJD96_RS11665	COG2814	Major facilitator Superfamily
BJD96_RS11670	COG0583	DNA-binding transcription factor activity
BJD96_RS11680	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
BJD96_RS11690	COG0217	transcriptional regulatory protein
BJD96_RS11700	COG3942	CHAP domain
BJD96_RS11700	COG1388	LysM domain
BJD96_RS11705	COG0306	phosphate transporter
BJD96_RS11710	COG1392	Phosphate transport regulator
BJD96_RS11715	COG2205	protein histidine kinase activity
BJD96_RS11720	COG0745	RESPONSE REGULATOR receiver
BJD96_RS11725	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BJD96_RS11740	COG4555	ABC transporter
BJD96_RS11760	COG3949	Membrane
BJD96_RS11770	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
BJD96_RS11780	COG2376	Dihydroxyacetone kinase
BJD96_RS11785	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BJD96_RS11790	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BJD96_RS11795	COG1120	ATPase activity
BJD96_RS11800	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BJD96_RS11805	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BJD96_RS11810	COG1132	(ABC) transporter
BJD96_RS11820	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
BJD96_RS11830	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
BJD96_RS11835	COG1682	transport, permease protein
BJD96_RS11840	COG1134	teichoic acid transport
BJD96_RS11845	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
BJD96_RS11855	COG1321	iron dependent repressor
BJD96_RS11865	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BJD96_RS11870	COG0803	Belongs to the bacterial solute-binding protein 9 family
BJD96_RS11880	COG1320	monovalent cation:proton antiporter activity
BJD96_RS11885	COG2212	antiporter activity
BJD96_RS11890	COG1863	multisubunit Na H antiporter MnhE subunit
BJD96_RS11895	COG0651	ATP synthesis coupled electron transport
BJD96_RS11900	COG1006	Multisubunit Na H antiporter MnhC subunit
BJD96_RS11905	COG2111	Na H antiporter
BJD96_RS11910	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BJD96_RS11910	COG2111	Na H antiporter
BJD96_RS11915	COG4974	Belongs to the 'phage' integrase family
BJD96_RS11950	COG0596	Alpha beta hydrolase
BJD96_RS11965	COG2267	carboxylic ester hydrolase activity
BJD96_RS11970	COG0546	phosphoglycolate phosphatase activity
BJD96_RS11975	COG4139	cobalamin transport
BJD96_RS11980	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BJD96_RS11985	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BJD96_RS11990	COG0018	arginyl-trna synthetase
BJD96_RS12005	COG1078	dGTPase activity
BJD96_RS12010	COG0456	acetyltransferase
BJD96_RS12015	COG0655	NAD(P)H dehydrogenase (quinone) activity
BJD96_RS12020	COG0667	Aldo Keto reductase
BJD96_RS12035	COG1028	Short-chain dehydrogenase reductase Sdr
BJD96_RS12040	COG4844	belongs to the
BJD96_RS12045	COG1082	Xylose isomerase domain protein TIM barrel
BJD96_RS12050	COG0673	inositol 2-dehydrogenase activity
BJD96_RS12060	COG0673	inositol 2-dehydrogenase activity
BJD96_RS12070	COG1263	PTS System
BJD96_RS12070	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BJD96_RS12090	COG0095	Lipoate-protein ligase
BJD96_RS12095	COG0280	phosphate acetyltransferase
BJD96_RS12100	COG3253	May function as heme-dependent peroxidase
BJD96_RS12135	COG2363	Small membrane protein
BJD96_RS12145	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
BJD96_RS12150	COG0351	phosphomethylpyrimidine kinase
BJD96_RS12180	COG0183	Belongs to the thiolase family
BJD96_RS12185	COG0318	PFAM AMP-dependent synthetase and ligase
BJD96_RS12195	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
BJD96_RS12200	COG0363	glucosamine-6-phosphate deaminase activity
BJD96_RS12210	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BJD96_RS12215	COG1469	GTP cyclohydrolase I activity
BJD96_RS12230	COG0431	NADPH-dependent FMN reductase
BJD96_RS12235	COG0561	phosphatase activity
BJD96_RS12245	COG1428	Deoxynucleoside kinase
BJD96_RS12250	COG1428	Deoxynucleoside kinase
BJD96_RS12260	COG0546	phosphoglycolate phosphatase activity
BJD96_RS12265	COG4297	protein containing double-stranded beta helix domain
BJD96_RS12270	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BJD96_RS12275	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BJD96_RS12285	COG0583	DNA-binding transcription factor activity
BJD96_RS12290	COG2814	Major facilitator Superfamily
BJD96_RS12305	COG0010	Belongs to the arginase family
BJD96_RS12310	COG1914	H( )-stimulated, divalent metal cation uptake system
BJD96_RS12315	COG3949	Membrane
BJD96_RS12320	COG1132	(ABC) transporter
BJD96_RS12325	COG1028	Short-chain dehydrogenase reductase Sdr
BJD96_RS12330	COG1312	Catalyzes the dehydration of D-mannonate
BJD96_RS12335	COG1904	glucuronate isomerase
BJD96_RS12360	COG0800	Aldolase
BJD96_RS12370	COG0583	DNA-binding transcription factor activity
BJD96_RS12400	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
BJD96_RS12425	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
BJD96_RS12430	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
BJD96_RS12450	COG1473	amidohydrolase
BJD96_RS12455	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BJD96_RS12460	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BJD96_RS12465	COG0049	tRNA binding
BJD96_RS12470	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
BJD96_RS12480	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
BJD96_RS12485	COG0085	RNA polymerase activity
BJD96_RS12490	COG2813	Specifically methylates the guanine in position
BJD96_RS12495	COG0222	ribosome binding
BJD96_RS12500	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
BJD96_RS12505	COG0081	regulation of translation
BJD96_RS12510	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
BJD96_RS12515	COG0250	Participates in transcription elongation, termination and antitermination
BJD96_RS12520	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BJD96_RS12525	COG0267	Belongs to the bacterial ribosomal protein bL33 family
BJD96_RS12540	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BJD96_RS12545	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
BJD96_RS12550	COG0215	cysteine-tRNA ligase activity
BJD96_RS12555	COG1045	serine acetyltransferase
BJD96_RS12560	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BJD96_RS12565	COG4956	integral membrane protein (PIN domain superfamily)
BJD96_RS12570	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
BJD96_RS12575	COG0542	response to heat
BJD96_RS12580	COG3869	Catalyzes the specific phosphorylation of arginine residues in
BJD96_RS12585	COG3880	PFAM UvrB UvrC protein
BJD96_RS12590	COG4463	regulation of RNA biosynthetic process
BJD96_RS12595	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BJD96_RS12600	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
BJD96_RS12605	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
BJD96_RS12610	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BJD96_RS12695	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
BJD96_RS12700	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BJD96_RS12720	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
BJD96_RS12725	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BJD96_RS12740	COG1098	S1 RNA binding domain
BJD96_RS12750	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
BJD96_RS12755	COG3956	TIGRFAM MazG family protein
BJD96_RS12760	COG2244	polysaccharide biosynthetic process
BJD96_RS12765	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BJD96_RS12770	COG0193	aminoacyl-tRNA hydrolase activity
BJD96_RS12775	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
BJD96_RS12780	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BJD96_RS12785	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
BJD96_RS12790	COG2088	sporulation resulting in formation of a cellular spore
BJD96_RS12795	COG0251	oxidation-reduction process
BJD96_RS12800	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BJD96_RS12805	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
BJD96_RS12810	COG4466	Protein conserved in bacteria
BJD96_RS12815	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
BJD96_RS12820	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
BJD96_RS12825	COG0084	hydrolase, TatD family'
BJD96_RS12830	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BJD96_RS12830	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BJD96_RS12835	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
BJD96_RS12840	COG2827	Endonuclease containing a URI domain
BJD96_RS12845	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
BJD96_RS12850	COG4467	Involved in initiation control of chromosome replication
BJD96_RS12855	COG1774	PSP1 C-terminal conserved region
BJD96_RS12860	COG0470	DNA polymerase III
BJD96_RS12865	COG3870	Protein conserved in bacteria
BJD96_RS12870	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
BJD96_RS12875	COG1982	Orn Lys Arg decarboxylase major
BJD96_RS12895	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
BJD96_RS12900	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
BJD96_RS12905	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BJD96_RS12920	COG2188	Transcriptional regulator
BJD96_RS12925	COG0366	Alpha amylase catalytic
BJD96_RS12930	COG1263	PTS System
BJD96_RS12930	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BJD96_RS12940	COG0493	'glutamate synthase
BJD96_RS12945	COG0067	glutamate synthase
BJD96_RS12945	COG0069	glutamate synthase activity
BJD96_RS12945	COG0070	glutamate synthase
BJD96_RS12980	COG1316	TRANSCRIPTIONal
BJD96_RS12990	COG0772	Belongs to the SEDS family
BJD96_RS12995	COG1051	belongs to the nudix hydrolase family
BJD96_RS13005	COG1388	LysM domain
BJD96_RS13005	COG3942	CHAP domain
BJD96_RS13015	COG0129	dihydroxy-acid dehydratase activity
BJD96_RS13025	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
BJD96_RS13030	COG0733	neurotransmitter:sodium symporter activity
BJD96_RS13035	COG1114	Component of the transport system for branched-chain amino acids
BJD96_RS13040	COG5646	InterPro IPR014922
BJD96_RS13045	COG1647	Serine aminopeptidase, S33
BJD96_RS13050	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
BJD96_RS13055	COG2807	transmembrane transport
BJD96_RS13070	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
BJD96_RS13075	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
BJD96_RS13080	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
BJD96_RS13085	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
BJD96_RS13090	COG3257	ureidoglycine aminohydrolase activity
BJD96_RS13095	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BJD96_RS13105	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BJD96_RS13110	COG0406	alpha-ribazole phosphatase activity
BJD96_RS13115	COG1115	amino acid carrier protein
BJD96_RS13120	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BJD96_RS13125	COG1953	Uracil, thiamine, allantoin
BJD96_RS13135	COG2814	Major facilitator Superfamily
BJD96_RS13140	COG2814	Major facilitator Superfamily
BJD96_RS13160	COG2140	Oxalate decarboxylase
BJD96_RS13165	COG0405	Gamma-glutamyltransferase
BJD96_RS13170	COG2233	PERMEase
BJD96_RS13210	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BJD96_RS13210	COG0519	Catalyzes the synthesis of GMP from XMP
BJD96_RS13215	COG0517	IMP dehydrogenase activity
BJD96_RS13215	COG0516	GMP reductase activity
BJD96_RS13220	COG2233	PERMEase
BJD96_RS13225	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BJD96_RS13240	COG5183	chlorophyll binding
BJD96_RS13245	COG1823	symporter activity
BJD96_RS13255	COG0778	Nitroreductase
BJD96_RS13260	COG0753	catalase activity
BJD96_RS13270	COG3279	Response regulator of the LytR AlgR family
BJD96_RS13285	COG0450	alkyl hydroperoxide reductase
BJD96_RS13290	COG3634	alkyl hydroperoxide reductase activity
BJD96_RS13305	COG0588	phosphoglycerate mutase activity
BJD96_RS13315	COG1280	lysine exporter protein (LysE YggA)
BJD96_RS13320	COG2076	Multidrug Resistance protein
BJD96_RS13325	COG2076	Multidrug Resistance protein
BJD96_RS13335	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BJD96_RS13350	COG4195	phage-related replication protein
BJD96_RS13395	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
BJD96_RS13405	COG0360	Binds together with S18 to 16S ribosomal RNA
BJD96_RS13415	COG1695	Transcriptional regulator
BJD96_RS13420	COG3479	Phenolic acid decarboxylase
BJD96_RS13425	COG0012	GTP binding
BJD96_RS13430	COG4481	Protein conserved in bacteria
BJD96_RS13435	COG0668	transmembrane transport
BJD96_RS13440	COG5609	conserved protein (DUF2294)
BJD96_RS13445	COG3002	Belongs to the UPF0753 family
BJD96_RS13450	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BJD96_RS13460	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BJD96_RS13470	COG2814	Major facilitator Superfamily
BJD96_RS13490	COG1388	LysM domain
BJD96_RS13515	COG1131	(ABC) transporter
BJD96_RS13555	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BJD96_RS13560	COG2210	Belongs to the sulfur carrier protein TusA family
BJD96_RS13565	COG1937	Protein conserved in bacteria
BJD96_RS13570	COG0730	response to heat
BJD96_RS13580	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BJD96_RS13590	COG3559	Exporter of polyketide antibiotics
BJD96_RS13595	COG1131	(ABC) transporter
BJD96_RS13625	COG0772	Belongs to the SEDS family
BJD96_RS13655	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
BJD96_RS13665	COG0529	Catalyzes the synthesis of activated sulfate
BJD96_RS13670	COG2046	Belongs to the sulfate adenylyltransferase family
BJD96_RS13675	COG0730	response to heat
BJD96_RS13690	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BJD96_RS13695	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BJD96_RS13700	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
BJD96_RS13705	COG0175	sulfate reduction
BJD96_RS13710	COG3620	sequence-specific DNA binding
BJD96_RS13735	COG1028	Short-chain dehydrogenase reductase Sdr
BJD96_RS13750	COG2311	Membrane
BJD96_RS13760	COG2188	Transcriptional regulator
BJD96_RS13765	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BJD96_RS13780	COG3964	amidohydrolase
BJD96_RS13785	COG1017	nitric oxide dioxygenase activity
BJD96_RS13785	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BJD96_RS13795	COG1475	DNA binding
BJD96_RS13805	COG0626	cystathionine gamma-synthase activity
BJD96_RS13810	COG0626	cystathionine gamma-synthase activity
BJD96_RS13815	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
BJD96_RS13815	COG0646	methionine synthase
BJD96_RS13820	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
BJD96_RS13830	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
BJD96_RS13850	COG0183	Belongs to the thiolase family
BJD96_RS13855	COG1250	3-hydroxyacyl-CoA dehydrogenase
BJD96_RS13855	COG1024	Enoyl-CoA hydratase
BJD96_RS13860	COG1960	acyl-CoA dehydrogenase activity
BJD96_RS13865	COG0318	PFAM AMP-dependent synthetase and ligase
BJD96_RS13885	COG4175	Glycine betaine
BJD96_RS13885	COG3448	diguanylate cyclase activity
BJD96_RS13890	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BJD96_RS13905	COG0561	phosphatase activity
BJD96_RS13910	COG1917	Cupin 2, conserved barrel domain protein
BJD96_RS13910	COG2207	Transcriptional regulator
BJD96_RS13915	COG0697	spore germination
BJD96_RS13925	COG1028	Short-chain dehydrogenase reductase Sdr
BJD96_RS13930	COG2239	Acts as a magnesium transporter
BJD96_RS13940	COG0531	amino acid
BJD96_RS13965	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BJD96_RS13975	COG1285	pathogenesis
BJD96_RS13990	COG3181	Tripartite tricarboxylate transporter family receptor
BJD96_RS13995	COG2271	Major facilitator Superfamily
BJD96_RS14005	COG1966	Carbon starvation protein
BJD96_RS14010	COG1475	DNA binding
BJD96_RS14015	COG0357	Ribosomal RNA small subunit methyltransferase G
BJD96_RS14020	COG0445	tRNA wobble uridine modification
BJD96_RS14025	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
BJD96_RS14030	COG0594	ribonuclease P activity
BJD96_RS14045	COG1192	Involved in chromosome partitioning
BJD96_RS14055	COG1216	Glycosyl transferase, family 2
BJD96_RS14075	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
BJD96_RS14090	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
BJD96_RS14090	COG1215	transferase activity, transferring glycosyl groups
BJD96_RS14145	COG1192	Involved in chromosome partitioning
BJD96_RS14170	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
BJD96_RS14190	COG3586	endonuclease activity
BJD96_RS14200	COG0583	DNA-binding transcription factor activity
BJD96_RS14205	COG1607	acyl-coa hydrolase
BJD96_RS14215	COG1063	alcohol dehydrogenase
BJD96_RS14220	COG4716	Myosin-crossreactive antigen
BJD96_RS14245	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BJD96_RS14250	COG0783	Belongs to the Dps family
BJD96_RS14410	COG1484	DNA-dependent DNA replication