locus-tag	class	description
BJG89_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
BJG89_RS00010	COG0592	DNA-directed DNA polymerase activity
BJG89_RS00015	COG2501	S4 domain
BJG89_RS00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
BJG89_RS00025	COG0187	DNA topoisomerase II activity
BJG89_RS00030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BJG89_RS00035	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
BJG89_RS00040	COG2986	histidine ammonia-lyase
BJG89_RS00045	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
BJG89_RS00050	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
BJG89_RS00060	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BJG89_RS00070	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
BJG89_RS00075	COG0359	binds to the 23S rRNA
BJG89_RS00080	COG0305	Participates in initiation and elongation during chromosome replication
BJG89_RS00085	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
BJG89_RS00090	COG1819	glycosyl
BJG89_RS00110	COG0477	Major facilitator Superfamily
BJG89_RS00115	COG0745	RESPONSE REGULATOR receiver
BJG89_RS00120	COG5002	protein histidine kinase activity
BJG89_RS00135	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
BJG89_RS00140	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
BJG89_RS00225	COG1442	glycosyl transferase family 8
BJG89_RS00225	COG1216	Glycosyl transferase, family 2
BJG89_RS00250	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BJG89_RS00300	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BJG89_RS00330	COG1288	antiporter activity
BJG89_RS00345	COG1473	amidohydrolase
BJG89_RS00385	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
BJG89_RS00390	COG1140	nitrate reductase beta subunit
BJG89_RS00400	COG2181	nitrate reductase activity
BJG89_RS00405	COG2223	nitrite transmembrane transporter activity
BJG89_RS00420	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BJG89_RS00420	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BJG89_RS00470	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
BJG89_RS00495	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
BJG89_RS00495	COG1215	transferase activity, transferring glycosyl groups
BJG89_RS00510	COG0640	Transcriptional regulator
BJG89_RS00515	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BJG89_RS00520	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BJG89_RS00535	COG0640	Transcriptional regulator
BJG89_RS00625	COG0789	Transcriptional regulator
BJG89_RS00635	COG0702	epimerase
BJG89_RS00640	COG2130	NADP-dependent
BJG89_RS00660	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
BJG89_RS00670	COG1653	transport
BJG89_RS00675	COG1175	transmembrane transport
BJG89_RS00680	COG0395	ABC-type sugar transport system, permease component
BJG89_RS00685	COG3842	ATPase activity
BJG89_RS00700	COG1846	Transcriptional regulator
BJG89_RS00710	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
BJG89_RS00715	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BJG89_RS00720	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BJG89_RS00725	COG1845	cytochrome c oxidase, subunit III
BJG89_RS00730	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
BJG89_RS00755	COG1349	DNA-binding transcription factor activity
BJG89_RS00760	COG1070	Carbohydrate kinase
BJG89_RS00765	COG4806	L-rhamnose isomerase
BJG89_RS00770	COG0235	Class ii aldolase
BJG89_RS00775	COG3254	rhamnose metabolic process
BJG89_RS00780	COG2814	Major facilitator Superfamily
BJG89_RS00785	COG1012	belongs to the aldehyde dehydrogenase family
BJG89_RS00825	COG4565	transcriptional regulatory protein
BJG89_RS00830	COG3493	citrate carrier protein
BJG89_RS00840	COG1846	Transcriptional regulator
BJG89_RS00845	COG3961	Belongs to the TPP enzyme family
BJG89_RS00865	COG1942	4-Oxalocrotonate Tautomerase
BJG89_RS00870	COG4145	pantothenate transmembrane transporter activity
BJG89_RS00880	COG1733	regulation of RNA biosynthetic process
BJG89_RS00885	COG1902	pentaerythritol trinitrate reductase activity
BJG89_RS00900	COG1705	Flagellar rod assembly protein muramidase FlgJ
BJG89_RS00900	COG3942	CHAP domain
BJG89_RS00910	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BJG89_RS00945	COG0702	epimerase
BJG89_RS00950	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
BJG89_RS00985	COG0415	Belongs to the DNA photolyase family
BJG89_RS00990	COG1335	isochorismatase
BJG89_RS00995	COG1522	sequence-specific DNA binding
BJG89_RS01000	COG1733	regulation of RNA biosynthetic process
BJG89_RS01025	COG0583	DNA-binding transcription factor activity
BJG89_RS01030	COG2190	(PTS) system
BJG89_RS01030	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BJG89_RS01030	COG1263	PTS System
BJG89_RS01035	COG2723	6-phospho-beta-galactosidase activity
BJG89_RS01050	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
BJG89_RS01055	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
BJG89_RS01060	COG1595	DNA-templated transcription, initiation
BJG89_RS01070	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BJG89_RS01080	COG1737	Transcriptional regulator
BJG89_RS01085	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BJG89_RS01090	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BJG89_RS01095	COG1447	Phosphotransferase system cellobiose-specific component IIA
BJG89_RS01115	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BJG89_RS01120	COG0471	metal ion transport
BJG89_RS01125	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
BJG89_RS01130	COG1028	Short-chain dehydrogenase reductase Sdr
BJG89_RS01135	COG0583	DNA-binding transcription factor activity
BJG89_RS01150	COG3711	transcriptional antiterminator
BJG89_RS01155	COG1263	PTS System
BJG89_RS01155	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BJG89_RS01155	COG2190	(PTS) system
BJG89_RS01160	COG0438	transferase activity, transferring glycosyl groups
BJG89_RS01165	COG0438	transferase activity, transferring glycosyl groups
BJG89_RS01170	COG1876	peptidase activity
BJG89_RS01180	COG0402	S-adenosylhomocysteine deaminase activity
BJG89_RS01185	COG2723	6-phospho-beta-galactosidase activity
BJG89_RS01190	COG2723	6-phospho-beta-galactosidase activity
BJG89_RS01195	COG2190	(PTS) system
BJG89_RS01195	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BJG89_RS01195	COG1263	PTS System
BJG89_RS01200	COG3711	transcriptional antiterminator
BJG89_RS01205	COG1309	transcriptional regulator
BJG89_RS01210	COG1511	domain protein
BJG89_RS01225	COG2207	Transcriptional regulator
BJG89_RS01230	COG2211	Major facilitator Superfamily
BJG89_RS01235	COG3250	beta-galactosidase activity
BJG89_RS01245	COG2271	Major facilitator Superfamily
BJG89_RS01255	COG3655	Transcriptional regulator
BJG89_RS01285	COG0579	oxidoreductase
BJG89_RS01290	COG4932	domain protein
BJG89_RS01290	COG5295	Hep Hag repeat protein
BJG89_RS01310	COG1028	Short-chain dehydrogenase reductase Sdr
BJG89_RS01315	COG1063	alcohol dehydrogenase
BJG89_RS01325	COG1063	alcohol dehydrogenase
BJG89_RS01330	COG3775	system Galactitol-specific IIC component
BJG89_RS01335	COG3414	Phosphotransferase system galactitol-specific IIB component
BJG89_RS01350	COG0471	metal ion transport
BJG89_RS01360	COG2318	DinB family
BJG89_RS01365	COG1388	LysM domain
BJG89_RS01370	COG0564	pseudouridine synthase activity
BJG89_RS01375	COG1388	LysM domain
BJG89_RS01380	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BJG89_RS01390	COG1054	Belongs to the UPF0176 family
BJG89_RS01405	COG1609	Transcriptional regulator
BJG89_RS01415	COG0235	Class ii aldolase
BJG89_RS01420	COG2160	L-arabinose isomerase activity
BJG89_RS01440	COG1511	domain protein
BJG89_RS01440	COG1511	domain protein
BJG89_RS01455	COG2207	Transcriptional regulator
BJG89_RS01455	COG1917	Cupin 2, conserved barrel domain protein
BJG89_RS01465	COG1328	CTP reductase activity
BJG89_RS01475	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
BJG89_RS01480	COG3583	domain protein
BJG89_RS01480	COG4932	domain protein
BJG89_RS01480	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
BJG89_RS01485	COG0431	NADPH-dependent FMN reductase
BJG89_RS01490	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BJG89_RS01495	COG0346	lactoylglutathione lyase activity
BJG89_RS01500	COG1136	(ABC) transporter
BJG89_RS01530	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
BJG89_RS01555	COG0477	Major facilitator Superfamily
BJG89_RS01565	COG2814	Major facilitator Superfamily
BJG89_RS01575	COG0584	glycerophosphoryl diester phosphodiesterase
BJG89_RS01585	COG0668	transmembrane transport
BJG89_RS01595	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
BJG89_RS01605	COG2211	Major facilitator Superfamily
BJG89_RS01610	COG1940	carbohydrate kinase activity
BJG89_RS01610	COG1846	Transcriptional regulator
BJG89_RS01615	COG2115	Belongs to the xylose isomerase family
BJG89_RS01620	COG1070	Carbohydrate kinase
BJG89_RS01625	COG0477	Major facilitator Superfamily
BJG89_RS01625	COG2814	Major facilitator Superfamily
BJG89_RS01635	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BJG89_RS01665	COG0673	inositol 2-dehydrogenase activity
BJG89_RS01675	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
BJG89_RS01680	COG1691	(AIR) carboxylase
BJG89_RS01685	COG1606	tRNA processing
BJG89_RS01690	COG3875	lactate racemase activity
BJG89_RS01705	COG3835	regulator
BJG89_RS01710	COG0574	Belongs to the PEP-utilizing enzyme family
BJG89_RS01710	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BJG89_RS01715	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
BJG89_RS01735	COG1476	TRANSCRIPTIONal
BJG89_RS01740	COG2807	transmembrane transport
BJG89_RS01750	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BJG89_RS01755	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BJG89_RS01760	COG1012	belongs to the aldehyde dehydrogenase family
BJG89_RS01765	COG0531	amino acid
BJG89_RS01785	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BJG89_RS01790	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BJG89_RS01795	COG1510	regulation of RNA biosynthetic process
BJG89_RS01800	COG1012	belongs to the aldehyde dehydrogenase family
BJG89_RS01805	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
BJG89_RS01810	COG0803	Belongs to the bacterial solute-binding protein 9 family
BJG89_RS01815	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BJG89_RS01825	COG0772	Belongs to the SEDS family
BJG89_RS01830	COG0463	Glycosyl transferase, family 2
BJG89_RS01830	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
BJG89_RS01835	COG0778	Nitroreductase
BJG89_RS01840	COG2843	Capsule synthesis protein
BJG89_RS01845	COG1957	nucleoside hydrolase
BJG89_RS01850	COG0477	Major facilitator Superfamily
BJG89_RS01870	COG1131	(ABC) transporter
BJG89_RS01880	COG1349	DNA-binding transcription factor activity
BJG89_RS01885	COG3842	ATPase activity
BJG89_RS01910	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BJG89_RS01915	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
BJG89_RS01920	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
BJG89_RS01925	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
BJG89_RS01935	COG0431	NADPH-dependent FMN reductase
BJG89_RS01945	COG1414	Transcriptional regulator
BJG89_RS01955	COG1063	alcohol dehydrogenase
BJG89_RS01960	COG1620	l-lactate permease
BJG89_RS01965	COG2814	Major facilitator Superfamily
BJG89_RS01975	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BJG89_RS01975	COG1263	PTS System
BJG89_RS01975	COG2190	(PTS) system
BJG89_RS01985	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BJG89_RS01995	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BJG89_RS02020	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BJG89_RS02025	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BJG89_RS02035	COG3037	sugar-specific permease SgaT UlaA
BJG89_RS02045	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BJG89_RS02050	COG1464	Belongs to the NlpA lipoprotein family
BJG89_RS02055	COG0039	L-malate dehydrogenase activity
BJG89_RS02060	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BJG89_RS02060	COG3711	transcriptional antiterminator
BJG89_RS02065	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BJG89_RS02065	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BJG89_RS02065	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BJG89_RS02070	COG1482	cell wall glycoprotein biosynthetic process
BJG89_RS02100	COG1309	transcriptional regulator
BJG89_RS02115	COG1309	transcriptional regulator
BJG89_RS02125	COG3949	Membrane
BJG89_RS02135	COG0829	nickel cation binding
BJG89_RS02140	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
BJG89_RS02145	COG0830	nickel cation binding
BJG89_RS02150	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
BJG89_RS02155	COG0804	urea catabolic process
BJG89_RS02160	COG0832	Belongs to the urease beta subunit family
BJG89_RS02165	COG0831	urea catabolic process
BJG89_RS02170	COG4413	Urea transporter
BJG89_RS02175	COG0747	negative chemotaxis
BJG89_RS02200	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BJG89_RS02215	COG0561	phosphatase activity
BJG89_RS02225	COG0167	dihydroorotate dehydrogenase activity
BJG89_RS02230	COG3001	Fructosamine kinase
BJG89_RS02295	COG1388	LysM domain
BJG89_RS02300	COG0436	Aminotransferase
BJG89_RS02310	COG2608	mercury ion transmembrane transporter activity
BJG89_RS02315	COG2217	Heavy metal translocating P-type atpase
BJG89_RS02320	COG0659	secondary active sulfate transmembrane transporter activity
BJG89_RS02325	COG1136	(ABC) transporter
BJG89_RS02330	COG0577	efflux transmembrane transporter activity
BJG89_RS02335	COG1028	Short-chain dehydrogenase reductase Sdr
BJG89_RS02350	COG0471	metal ion transport
BJG89_RS02355	COG5505	Protein of unknown function (DUF819)
BJG89_RS02370	COG4336	lyase activity
BJG89_RS02385	COG1012	belongs to the aldehyde dehydrogenase family
BJG89_RS02395	COG2409	Drug exporters of the RND superfamily
BJG89_RS02410	COG1473	amidohydrolase
BJG89_RS02430	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BJG89_RS02435	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BJG89_RS02440	COG3425	synthase
BJG89_RS02445	COG0183	Belongs to the thiolase family
BJG89_RS02455	COG3386	PFAM SMP-30 Gluconolaconase
BJG89_RS02460	COG1757	Na H antiporter
BJG89_RS02465	COG0583	DNA-binding transcription factor activity
BJG89_RS02480	COG0028	Belongs to the TPP enzyme family
BJG89_RS02485	COG1288	antiporter activity
BJG89_RS02500	COG2515	1-aminocyclopropane-1-carboxylate deaminase
BJG89_RS02515	COG0657	acetylesterase activity
BJG89_RS02530	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
BJG89_RS02540	COG2843	Capsule synthesis protein
BJG89_RS02555	COG3949	Membrane
BJG89_RS02575	COG1129	ABC transporter
BJG89_RS02585	COG1609	Transcriptional regulator
BJG89_RS02595	COG1070	Carbohydrate kinase
BJG89_RS02600	COG1063	alcohol dehydrogenase
BJG89_RS02620	COG3764	Sortase (surface protein transpeptidase)
BJG89_RS02625	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
BJG89_RS02630	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BJG89_RS02640	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BJG89_RS02645	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BJG89_RS02650	COG0561	phosphatase activity
BJG89_RS02655	COG0778	Nitroreductase
BJG89_RS02665	COG2514	catechol 2,3-dioxygenase activity
BJG89_RS02670	COG1132	(ABC) transporter
BJG89_RS02675	COG1132	(ABC) transporter
BJG89_RS02690	COG1012	belongs to the aldehyde dehydrogenase family
BJG89_RS02695	COG1846	Transcriptional regulator
BJG89_RS02700	COG0346	lactoylglutathione lyase activity
BJG89_RS02705	COG0346	lactoylglutathione lyase activity
BJG89_RS02710	COG0400	carboxylic ester hydrolase activity
BJG89_RS02715	COG3949	Membrane
BJG89_RS02720	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
BJG89_RS02725	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BJG89_RS02730	COG0586	Pfam SNARE associated Golgi protein
BJG89_RS02735	COG2271	Major facilitator Superfamily
BJG89_RS02745	COG3527	Alpha-acetolactate decarboxylase
BJG89_RS02750	COG1289	transmembrane transporter activity
BJG89_RS02765	COG4876	unkown
BJG89_RS02770	COG2357	RelA SpoT domain protein
BJG89_RS02775	COG1802	Transcriptional regulator
BJG89_RS02780	COG1070	Carbohydrate kinase
BJG89_RS02785	COG2610	gluconate transmembrane transporter activity
BJG89_RS02790	COG1028	Short-chain dehydrogenase reductase Sdr
BJG89_RS02795	COG3949	Membrane
BJG89_RS02805	COG2211	Major facilitator Superfamily
BJG89_RS02810	COG3250	beta-galactosidase activity
BJG89_RS02830	COG2211	Major facilitator Superfamily
BJG89_RS02840	COG1312	Catalyzes the dehydration of D-mannonate
BJG89_RS02860	COG4221	oxidoreductase activity
BJG89_RS02870	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BJG89_RS02880	COG0107	imidazoleglycerol-phosphate synthase activity
BJG89_RS02885	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
BJG89_RS02890	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
BJG89_RS02895	COG0131	Imidazoleglycerol-phosphate dehydratase
BJG89_RS02900	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BJG89_RS02905	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
BJG89_RS02910	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
BJG89_RS02920	COG3048	D-serine ammonia-lyase activity
BJG89_RS02925	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
BJG89_RS02930	COG0248	Ppx GppA phosphatase
BJG89_RS02935	COG1028	Short-chain dehydrogenase reductase Sdr
BJG89_RS02940	COG1363	Peptidase, m42
BJG89_RS02950	COG0069	glutamate synthase activity
BJG89_RS02960	COG4619	ABC transporter
BJG89_RS02965	COG0390	transport system, permease component
BJG89_RS02970	COG2814	Major facilitator Superfamily
BJG89_RS02975	COG2851	Citrate transporter
BJG89_RS02980	COG0531	amino acid
BJG89_RS02985	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
BJG89_RS02995	COG3246	L-lysine catabolic process to acetate
BJG89_RS03000	COG1250	3-hydroxyacyl-CoA dehydrogenase
BJG89_RS03015	COG1174	glycine betaine transport
BJG89_RS03025	COG1174	glycine betaine transport
BJG89_RS03040	COG4187	Peptidase family M20/M25/M40
BJG89_RS03060	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
BJG89_RS03090	COG2814	Major facilitator Superfamily
BJG89_RS03100	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BJG89_RS03105	COG1388	LysM domain
BJG89_RS03110	COG0588	phosphoglycerate mutase activity
BJG89_RS03120	COG2814	Major facilitator Superfamily
BJG89_RS03145	COG2353	YceI-like domain
BJG89_RS03155	COG1695	Transcriptional regulator
BJG89_RS03180	COG2116	formate transmembrane transporter activity
BJG89_RS03185	COG0454	-acetyltransferase
BJG89_RS03195	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BJG89_RS03195	COG1648	precorrin-2 dehydrogenase activity
BJG89_RS03200	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BJG89_RS03205	COG2146	nitrite reductase [NAD(P)H] activity
BJG89_RS03210	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BJG89_RS03215	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
BJG89_RS03220	COG1140	nitrate reductase beta subunit
BJG89_RS03230	COG2181	nitrate reductase activity
BJG89_RS03240	COG4585	Histidine kinase
BJG89_RS03265	COG1846	Transcriptional regulator
BJG89_RS03305	COG1263	PTS System
BJG89_RS03305	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BJG89_RS03315	COG1283	sodium-dependent phosphate transmembrane transporter activity
BJG89_RS03320	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BJG89_RS03325	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BJG89_RS03330	COG1288	antiporter activity
BJG89_RS03335	COG1349	DNA-binding transcription factor activity
BJG89_RS03340	COG1063	alcohol dehydrogenase
BJG89_RS03345	COG2376	Dihydroxyacetone kinase
BJG89_RS03355	COG0698	ribose 5-phosphate isomerase
BJG89_RS03375	COG0492	ferredoxin-NADP+ reductase activity
BJG89_RS03385	COG2814	Major facilitator Superfamily
BJG89_RS03390	COG0604	alcohol dehydrogenase
BJG89_RS03405	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
BJG89_RS03410	COG1620	l-lactate permease
BJG89_RS03415	COG0438	transferase activity, transferring glycosyl groups
BJG89_RS03425	COG5002	protein histidine kinase activity
BJG89_RS03425	COG3850	Histidine kinase
BJG89_RS03430	COG0745	RESPONSE REGULATOR receiver
BJG89_RS03435	COG0577	efflux transmembrane transporter activity
BJG89_RS03440	COG1136	(ABC) transporter
BJG89_RS03455	COG4640	response to antibiotic
BJG89_RS03460	COG2814	Major facilitator Superfamily
BJG89_RS03470	COG1566	PFAM secretion protein HlyD family protein
BJG89_RS03475	COG2814	Major facilitator Superfamily
BJG89_RS03510	COG1304	FMN binding
BJG89_RS03515	COG0786	glutamate:sodium symporter activity
BJG89_RS03520	COG1695	Transcriptional regulator
BJG89_RS03535	COG1757	Na H antiporter
BJG89_RS03540	COG2094	Belongs to the DNA glycosylase MPG family
BJG89_RS03545	COG3152	Membrane
BJG89_RS03550	COG1069	ribulokinase activity
BJG89_RS03555	COG4152	abc transporter atp-binding protein
BJG89_RS03560	COG1668	transmembrane transport
BJG89_RS03565	COG2017	converts alpha-aldose to the beta-anomer
BJG89_RS03570	COG2258	MOSC domain
BJG89_RS03575	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
BJG89_RS03580	COG1266	CAAX protease self-immunity
BJG89_RS03585	COG0010	Belongs to the arginase family
BJG89_RS03590	COG0583	DNA-binding transcription factor activity
BJG89_RS03595	COG3314	Sporulation integral membrane protein YlbJ
BJG89_RS03600	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
BJG89_RS03605	COG1228	amidohydrolase
BJG89_RS03610	COG0659	secondary active sulfate transmembrane transporter activity
BJG89_RS03615	COG1473	amidohydrolase
BJG89_RS03620	COG1028	Short-chain dehydrogenase reductase Sdr
BJG89_RS03625	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BJG89_RS03645	COG1263	PTS System
BJG89_RS03645	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BJG89_RS03655	COG0385	Bile acid
BJG89_RS03660	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BJG89_RS03685	COG1113	amino acid transport
BJG89_RS03690	COG1785	Belongs to the alkaline phosphatase family
BJG89_RS03700	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BJG89_RS03700	COG1263	PTS System
BJG89_RS03705	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
BJG89_RS03730	COG0483	inositol monophosphate 1-phosphatase activity
BJG89_RS03735	COG1316	TRANSCRIPTIONal
BJG89_RS03740	COG3383	formate dehydrogenase (NAD+) activity
BJG89_RS03765	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BJG89_RS03775	COG2076	Multidrug Resistance protein
BJG89_RS03780	COG3942	CHAP domain
BJG89_RS03795	COG1757	Na H antiporter
BJG89_RS03805	COG3942	CHAP domain
BJG89_RS03830	COG0765	amino acid transport
BJG89_RS03835	COG0765	amino acid transport
BJG89_RS03845	COG1126	abc transporter atp-binding protein
BJG89_RS03850	COG1960	acyl-CoA dehydrogenase activity
BJG89_RS03855	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BJG89_RS03860	COG1268	BioY protein
BJG89_RS03870	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
BJG89_RS03875	COG1609	Transcriptional regulator
BJG89_RS03880	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
BJG89_RS03885	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BJG89_RS03890	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
BJG89_RS03895	COG0725	ABC transporter, periplasmic molybdate-binding protein
BJG89_RS03900	COG4149	molybdate abc transporter
BJG89_RS03905	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
BJG89_RS03915	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BJG89_RS03920	COG0521	Mo-molybdopterin cofactor biosynthetic process
BJG89_RS03925	COG0315	cyclic pyranopterin monophosphate synthase activity
BJG89_RS03950	COG0746	molybdenum cofactor guanylyltransferase activity
BJG89_RS03955	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BJG89_RS03965	COG2814	Major facilitator Superfamily
BJG89_RS03985	COG2348	transferase activity, transferring amino-acyl groups
BJG89_RS03990	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BJG89_RS04020	COG4975	Glucose uptake
BJG89_RS04030	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BJG89_RS04030	COG0551	DNA topoisomerase type I activity
BJG89_RS04035	COG2252	PERMEase
BJG89_RS04045	COG0051	transcription antitermination factor activity, RNA binding
BJG89_RS04050	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
BJG89_RS04055	COG0088	Forms part of the polypeptide exit tunnel
BJG89_RS04060	COG0089	rRNA binding
BJG89_RS04065	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
BJG89_RS04070	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
BJG89_RS04075	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
BJG89_RS04080	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
BJG89_RS04085	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
BJG89_RS04090	COG0255	Belongs to the universal ribosomal protein uL29 family
BJG89_RS04095	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
BJG89_RS04100	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
BJG89_RS04105	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
BJG89_RS04110	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
BJG89_RS04115	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
BJG89_RS04120	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
BJG89_RS04125	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
BJG89_RS04130	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
BJG89_RS04135	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
BJG89_RS04140	COG1841	ribosomal large subunit assembly
BJG89_RS04145	COG0200	Binds to the 23S rRNA
BJG89_RS04150	COG0201	protein transport
BJG89_RS04155	COG0563	adenylate kinase activity
BJG89_RS04165	COG0257	Belongs to the bacterial ribosomal protein bL36 family
BJG89_RS04170	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
BJG89_RS04180	COG0202	RNA polymerase activity
BJG89_RS04185	COG0203	ribosomal protein L17
BJG89_RS04190	COG1122	ATPase activity
BJG89_RS04195	COG1122	ATPase activity
BJG89_RS04205	COG0101	tRNA pseudouridine synthase activity
BJG89_RS04210	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
BJG89_RS04225	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BJG89_RS04230	COG2130	NADP-dependent
BJG89_RS04235	COG0604	alcohol dehydrogenase
BJG89_RS04240	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BJG89_RS04255	COG1302	Protein conserved in bacteria
BJG89_RS04265	COG2814	Major facilitator Superfamily
BJG89_RS04270	COG4264	IucA IucC family
BJG89_RS04275	COG3457	Alanine racemase
BJG89_RS04280	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
BJG89_RS04285	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BJG89_RS04290	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BJG89_RS04295	COG3314	Sporulation integral membrane protein YlbJ
BJG89_RS04300	COG2329	Antibiotic biosynthesis monooxygenase
BJG89_RS04310	COG1988	membrane-bound metal-dependent
BJG89_RS04315	COG4284	Utp--glucose-1-phosphate uridylyltransferase
BJG89_RS04320	COG1272	protein, Hemolysin III
BJG89_RS04335	COG2814	Major facilitator Superfamily
BJG89_RS04340	COG0489	protein tyrosine kinase activity
BJG89_RS04395	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
BJG89_RS04405	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BJG89_RS04410	COG0246	Mannitol dehydrogenase
BJG89_RS04420	COG3711	transcriptional antiterminator
BJG89_RS04425	COG2213	PTS system mannitol-specific
BJG89_RS04440	COG1119	ATPase activity
BJG89_RS04470	COG0702	epimerase
BJG89_RS04475	COG2186	Transcriptional regulator
BJG89_RS04480	COG1482	cell wall glycoprotein biosynthetic process
BJG89_RS04490	COG2855	membrane
BJG89_RS04505	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BJG89_RS04510	COG0783	Belongs to the Dps family
BJG89_RS04515	COG0813	purine-nucleoside phosphorylase activity
BJG89_RS04520	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
BJG89_RS04525	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
BJG89_RS04530	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
BJG89_RS04540	COG1854	S-ribosylhomocysteine lyase activity
BJG89_RS04560	COG5146	pantothenate kinase activity
BJG89_RS04565	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BJG89_RS04570	COG3343	RNA polymerase activity
BJG89_RS04575	COG0504	CTP synthase activity
BJG89_RS04590	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BJG89_RS04600	COG1012	belongs to the aldehyde dehydrogenase family
BJG89_RS04605	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
BJG89_RS04610	COG0254	rRNA binding
BJG89_RS04615	COG1435	thymidine kinase activity
BJG89_RS04620	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
BJG89_RS04625	COG2890	protein-(glutamine-N5) methyltransferase activity
BJG89_RS04630	COG0009	L-threonylcarbamoyladenylate synthase
BJG89_RS04635	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BJG89_RS04640	COG4475	Protein of unknown function (DUF436)
BJG89_RS04645	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
BJG89_RS04650	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
BJG89_RS04655	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
BJG89_RS04665	COG0356	it plays a direct role in the translocation of protons across the membrane
BJG89_RS04670	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BJG89_RS04675	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
BJG89_RS04680	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BJG89_RS04685	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
BJG89_RS04690	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
BJG89_RS04695	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
BJG89_RS04700	COG0355	proton-transporting ATP synthase activity, rotational mechanism
BJG89_RS04710	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BJG89_RS04715	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BJG89_RS04725	COG0629	single-stranded DNA binding
BJG89_RS04730	COG1388	LysM domain
BJG89_RS04735	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
BJG89_RS04745	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
BJG89_RS04750	COG0352	thiamine-phosphate diphosphorylase activity
BJG89_RS04755	COG0706	membrane insertase activity
BJG89_RS04760	COG1418	mRNA catabolic process
BJG89_RS04770	COG1937	Protein conserved in bacteria
BJG89_RS04790	COG0772	Belongs to the SEDS family
BJG89_RS04795	COG1181	Belongs to the D-alanine--D-alanine ligase family
BJG89_RS04800	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BJG89_RS04805	COG0513	Belongs to the DEAD box helicase family
BJG89_RS04815	COG3428	Bacterial PH domain
BJG89_RS04825	COG0736	holo-[acyl-carrier-protein] synthase activity
BJG89_RS04830	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BJG89_RS04840	COG2337	Toxic component of a toxin-antitoxin (TA) module
BJG89_RS04845	COG2208	phosphoserine phosphatase activity
BJG89_RS04860	COG1191	sigma factor activity
BJG89_RS04865	COG2183	response to ionizing radiation
BJG89_RS04885	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BJG89_RS04950	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BJG89_RS04955	COG0066	3-isopropylmalate dehydratase activity
BJG89_RS04960	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
BJG89_RS04965	COG0473	3-isopropylmalate dehydrogenase activity
BJG89_RS04970	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BJG89_RS04975	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
BJG89_RS04980	COG0440	acetolactate synthase activity
BJG89_RS04985	COG0028	Belongs to the TPP enzyme family
BJG89_RS04990	COG0129	dihydroxy-acid dehydratase activity
BJG89_RS04995	COG0802	atpase or kinase
BJG89_RS05000	COG1214	PFAM Peptidase M22, glycoprotease
BJG89_RS05005	COG0456	acetyltransferase
BJG89_RS05010	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
BJG89_RS05030	COG0488	(ABC) transporter
BJG89_RS05035	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
BJG89_RS05040	COG2391	methyltransferase activity
BJG89_RS05045	COG0425	Belongs to the sulfur carrier protein TusA family
BJG89_RS05050	COG1609	Transcriptional regulator
BJG89_RS05055	COG1621	beta-fructofuranosidase activity
BJG89_RS05065	COG3279	Response regulator of the LytR AlgR family
BJG89_RS05070	COG3290	protein histidine kinase activity
BJG89_RS05080	COG4512	PFAM Accessory gene regulator B
BJG89_RS05085	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BJG89_RS05105	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
BJG89_RS05110	COG0459	protein refolding
BJG89_RS05135	COG1725	Transcriptional regulator
BJG89_RS05150	COG1131	(ABC) transporter
BJG89_RS05195	COG2706	6-phosphogluconolactonase activity
BJG89_RS05200	COG1012	belongs to the aldehyde dehydrogenase family
BJG89_RS05205	COG1227	inorganic diphosphatase activity
BJG89_RS05210	COG1335	isochorismatase
BJG89_RS05220	COG0471	metal ion transport
BJG89_RS05225	COG0077	Prephenate dehydratase
BJG89_RS05235	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
BJG89_RS05240	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
BJG89_RS05245	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
BJG89_RS05255	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BJG89_RS05260	COG4496	protein, YerC YecD
BJG89_RS05275	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
BJG89_RS05280	COG4851	CamS sex pheromone cAM373 precursor
BJG89_RS05285	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BJG89_RS05290	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BJG89_RS05295	COG0154	amidase activity
BJG89_RS05300	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BJG89_RS05305	COG1597	lipid kinase activity
BJG89_RS05310	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BJG89_RS05320	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BJG89_RS05330	COG1528	Iron-storage protein
BJG89_RS05345	COG4129	membrane
BJG89_RS05350	COG0024	Methionine aminopeptidase
BJG89_RS05365	COG4585	Histidine kinase
BJG89_RS05370	COG2197	response regulator
BJG89_RS05375	COG1295	ribonuclease BN
BJG89_RS05385	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BJG89_RS05390	COG4840	Belongs to the UPF0435 family
BJG89_RS05395	COG2309	aminopeptidase activity
BJG89_RS05400	COG1607	acyl-coa hydrolase
BJG89_RS05405	COG0535	radical SAM domain protein
BJG89_RS05415	COG0693	protein deglycase activity
BJG89_RS05420	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BJG89_RS05425	COG2137	regulation of response to DNA damage stimulus
BJG89_RS05435	COG1134	teichoic acid transport
BJG89_RS05445	COG1988	membrane-bound metal-dependent
BJG89_RS05450	COG1194	a g-specific adenine glycosylase
BJG89_RS05455	COG3557	Belongs to the UPF0374 family
BJG89_RS05465	COG4129	membrane
BJG89_RS05470	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
BJG89_RS05475	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BJG89_RS05485	COG0735	belongs to the Fur family
BJG89_RS05645	COG0765	amino acid transport
BJG89_RS05650	COG1126	abc transporter atp-binding protein
BJG89_RS05655	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
BJG89_RS05665	COG0363	glucosamine-6-phosphate deaminase activity
BJG89_RS05680	COG0114	fumarate hydratase activity
BJG89_RS05685	COG0564	pseudouridine synthase activity
BJG89_RS05690	COG2203	Gaf domain
BJG89_RS05690	COG4585	Histidine kinase
BJG89_RS05695	COG2197	response regulator
BJG89_RS05700	COG1301	dicarboxylic acid transport
BJG89_RS05715	COG0788	formyltetrahydrofolate deformylase activity
BJG89_RS05725	COG4399	Belongs to the UPF0754 family
BJG89_RS05730	COG3679	Belongs to the UPF0342 family
BJG89_RS05735	COG0420	3'-5' exonuclease activity
BJG89_RS05740	COG4717	serine-type aminopeptidase activity
BJG89_RS05750	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BJG89_RS05765	COG0537	adenosine 5'-monophosphoramidase activity
BJG89_RS05770	COG1131	(ABC) transporter
BJG89_RS05775	COG4473	ABC transporter
BJG89_RS05785	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
BJG89_RS05790	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
BJG89_RS05795	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
BJG89_RS05800	COG3545	Serine hydrolase
BJG89_RS05865	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
BJG89_RS05875	COG1506	peptidase
BJG89_RS05885	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
BJG89_RS05890	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
BJG89_RS05900	COG0656	L-ascorbic acid biosynthetic process
BJG89_RS05905	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BJG89_RS05910	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BJG89_RS05920	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BJG89_RS05940	COG1595	DNA-templated transcription, initiation
BJG89_RS05965	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BJG89_RS05965	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BJG89_RS05970	COG0307	riboflavin synthase, alpha
BJG89_RS05975	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BJG89_RS05975	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BJG89_RS05980	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
BJG89_RS05990	COG2267	carboxylic ester hydrolase activity
BJG89_RS05995	COG0039	L-malate dehydrogenase activity
BJG89_RS06005	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
BJG89_RS06010	COG1242	4 iron, 4 sulfur cluster binding
BJG89_RS06015	COG2814	Major facilitator Superfamily
BJG89_RS06020	COG0495	leucyl-tRNA aminoacylation
BJG89_RS06030	COG2081	HI0933 family
BJG89_RS06035	COG2244	polysaccharide biosynthetic process
BJG89_RS06040	COG1187	pseudouridine synthase activity
BJG89_RS06050	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BJG89_RS06055	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BJG89_RS06060	COG0510	thiamine kinase activity
BJG89_RS06065	COG0220	tRNA (guanine-N7-)-methyltransferase activity
BJG89_RS06070	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BJG89_RS06080	COG1363	Peptidase, m42
BJG89_RS06085	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BJG89_RS06090	COG4848	Belongs to the UPF0354 family
BJG89_RS06095	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BJG89_RS06100	COG1674	ftsk spoiiie
BJG89_RS06105	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BJG89_RS06110	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
BJG89_RS06120	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
BJG89_RS06120	COG1605	Chorismate mutase
BJG89_RS06125	COG1609	Transcriptional regulator
BJG89_RS06130	COG0123	including yeast histone deacetylase and acetoin utilization protein
BJG89_RS06135	COG0454	-acetyltransferase
BJG89_RS06140	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BJG89_RS06155	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BJG89_RS06160	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BJG89_RS06165	COG0204	Acyl-transferase
BJG89_RS06170	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BJG89_RS06170	COG1263	PTS System
BJG89_RS06180	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BJG89_RS06185	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
BJG89_RS06190	COG1764	response to oxidative stress
BJG89_RS06195	COG0584	glycerophosphoryl diester phosphodiesterase
BJG89_RS06205	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
BJG89_RS06215	COG1956	GAF domain-containing protein
BJG89_RS06220	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
BJG89_RS06225	COG1104	cysteine desulfurase activity
BJG89_RS06230	COG0301	tRNA thio-modification
BJG89_RS06235	COG0730	response to heat
BJG89_RS06240	COG0616	signal peptide processing
BJG89_RS06245	COG1714	RDD family
BJG89_RS06250	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
BJG89_RS06260	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
BJG89_RS06270	COG0589	response to stress
BJG89_RS06275	COG0686	Belongs to the AlaDH PNT family
BJG89_RS06280	COG3142	Participates in the control of copper homeostasis
BJG89_RS06285	COG0006	proline dipeptidase activity
BJG89_RS06290	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
BJG89_RS06300	COG4109	DRTGG domain
BJG89_RS06305	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
BJG89_RS06315	COG0281	malic enzyme
BJG89_RS06320	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
BJG89_RS06325	COG0825	malonyl-CoA metabolic process
BJG89_RS06330	COG0205	6-phosphofructokinase activity
BJG89_RS06335	COG0469	pyruvate kinase activity
BJG89_RS06340	COG1113	amino acid transport
BJG89_RS06345	COG0372	Belongs to the citrate synthase family
BJG89_RS06350	COG0538	isocitrate dehydrogenase activity
BJG89_RS06355	COG0745	RESPONSE REGULATOR receiver
BJG89_RS06360	COG5002	protein histidine kinase activity
BJG89_RS06370	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BJG89_RS06370	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BJG89_RS06375	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
BJG89_RS06380	COG0237	dephospho-CoA kinase activity
BJG89_RS06390	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
BJG89_RS06400	COG1484	DNA-dependent DNA replication
BJG89_RS06405	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BJG89_RS06410	COG0833	amino acid
BJG89_RS06415	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
BJG89_RS06420	COG0291	Belongs to the bacterial ribosomal protein bL35 family
BJG89_RS06430	COG4112	unkown
BJG89_RS06440	COG0544	peptidyl-prolyl cis-trans isomerase activity
BJG89_RS06445	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
BJG89_RS06450	COG0218	Necessary for normal cell division and for the maintenance of normal septation
BJG89_RS06455	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
BJG89_RS06460	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BJG89_RS06465	COG0181	hydroxymethylbilane synthase activity
BJG89_RS06475	COG0113	porphobilinogen synthase activity
BJG89_RS06480	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
BJG89_RS06490	COG2818	Glycosylase
BJG89_RS06495	COG0525	valine-tRNA ligase activity
BJG89_RS06500	COG0285	dihydrofolate synthase activity
BJG89_RS06510	COG0656	L-ascorbic acid biosynthetic process
BJG89_RS06535	COG3708	Transcriptional regulator
BJG89_RS06535	COG2207	Transcriptional regulator
BJG89_RS06545	COG2003	Belongs to the UPF0758 family
BJG89_RS06575	COG0261	This protein binds to 23S rRNA in the presence of protein L20
BJG89_RS06580	COG2868	ribosomal protein
BJG89_RS06585	COG0211	Belongs to the bacterial ribosomal protein bL27 family
BJG89_RS06590	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
BJG89_RS06595	COG4492	Belongs to the UPF0735 family
BJG89_RS06600	COG0632	four-way junction helicase activity
BJG89_RS06605	COG2255	four-way junction helicase activity
BJG89_RS06610	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
BJG89_RS06615	COG0343	queuine tRNA-ribosyltransferase activity
BJG89_RS06620	COG1862	Preprotein translocase
BJG89_RS06625	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BJG89_RS06625	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BJG89_RS06630	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BJG89_RS06630	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
BJG89_RS06645	COG1490	D-aminoacyl-tRNA deacylase activity
BJG89_RS06650	COG0860	N-Acetylmuramoyl-L-alanine amidase
BJG89_RS06655	COG0124	histidyl-tRNA synthetase
BJG89_RS06660	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
BJG89_RS06670	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
BJG89_RS06675	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BJG89_RS06680	COG1959	2 iron, 2 sulfur cluster binding
BJG89_RS06690	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BJG89_RS06695	COG0488	(ABC) transporter
BJG89_RS06700	COG1104	cysteine desulfurase activity
BJG89_RS06705	COG0482	sulfurtransferase activity
BJG89_RS06715	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BJG89_RS06720	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BJG89_RS06725	COG4472	Bacterial protein of unknown function (DUF965)
BJG89_RS06730	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
BJG89_RS06735	COG3906	Belongs to the UPF0473 family
BJG89_RS06745	COG0826	peptidase U32
BJG89_RS06750	COG0826	peptidase U32
BJG89_RS06755	COG0572	uridine kinase
BJG89_RS06765	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
BJG89_RS06770	COG1984	allophanate hydrolase subunit 2
BJG89_RS06780	COG0439	Biotin carboxylase
BJG89_RS06785	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
BJG89_RS06790	COG1914	H( )-stimulated, divalent metal cation uptake system
BJG89_RS06795	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BJG89_RS06800	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
BJG89_RS06805	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
BJG89_RS06810	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BJG89_RS06815	COG1534	Rna-binding protein
BJG89_RS06820	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
BJG89_RS06825	COG1713	HD superfamily hydrolase involved in NAD metabolism
BJG89_RS06830	COG0799	negative regulation of ribosome biogenesis
BJG89_RS06840	COG1555	photosystem II stabilization
BJG89_RS06845	COG2131	deaminase
BJG89_RS06850	COG0658	competence protein
BJG89_RS06850	COG2333	competence protein COMEC
BJG89_RS06855	COG1466	dna polymerase III delta subunit
BJG89_RS06860	COG0268	Binds directly to 16S ribosomal RNA
BJG89_RS06865	COG0481	GTPase activity
BJG89_RS06870	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BJG89_RS06875	COG1420	regulation of RNA biosynthetic process
BJG89_RS06880	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
BJG89_RS06885	COG0443	Heat shock 70 kDa protein
BJG89_RS06890	COG0484	heat shock protein binding
BJG89_RS06895	COG2264	protein methyltransferase activity
BJG89_RS06900	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BJG89_RS06905	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BJG89_RS06910	COG0828	Belongs to the bacterial ribosomal protein bS21 family
BJG89_RS06915	COG1030	water channel activity
BJG89_RS06920	COG4864	UPF0365 protein
BJG89_RS06930	COG1702	phosphate starvation-inducible protein PhoH
BJG89_RS06935	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
BJG89_RS06950	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
BJG89_RS06955	COG1381	Involved in DNA repair and RecF pathway recombination
BJG89_RS06960	COG0423	glycine-tRNA ligase activity
BJG89_RS06965	COG0517	IMP dehydrogenase activity
BJG89_RS06970	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
BJG89_RS06980	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BJG89_RS06985	COG2384	SAM-dependent methyltransferase
BJG89_RS06990	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BJG89_RS06995	COG0513	Belongs to the DEAD box helicase family
BJG89_RS07000	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
BJG89_RS07005	COG1121	(ABC) transporter
BJG89_RS07010	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BJG89_RS07020	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BJG89_RS07025	COG0768	penicillin binding
BJG89_RS07030	COG0267	Belongs to the bacterial ribosomal protein bL33 family
BJG89_RS07035	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BJG89_RS07040	COG0457	Tetratricopeptide repeat
BJG89_RS07040	COG0705	Rhomboid family
BJG89_RS07045	COG4483	Protein conserved in bacteria
BJG89_RS07050	COG1940	carbohydrate kinase activity
BJG89_RS07055	COG0011	TIGRFAM Protein of
BJG89_RS07060	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BJG89_RS07065	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BJG89_RS07070	COG1459	type II secretion system
BJG89_RS07075	COG4537	Required for transformation and DNA binding
BJG89_RS07100	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
BJG89_RS07105	COG0404	The glycine cleavage system catalyzes the degradation of glycine
BJG89_RS07110	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BJG89_RS07115	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BJG89_RS07120	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BJG89_RS07125	COG0095	Lipoate-protein ligase
BJG89_RS07140	COG0006	proline dipeptidase activity
BJG89_RS07145	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
BJG89_RS07150	COG0511	ligase activity, forming carbon-carbon bonds
BJG89_RS07155	COG0439	Biotin carboxylase
BJG89_RS07160	COG1302	Protein conserved in bacteria
BJG89_RS07165	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BJG89_RS07170	COG1570	exodeoxyribonuclease VII activity
BJG89_RS07185	COG1438	arginine binding
BJG89_RS07190	COG0497	DNA recombination
BJG89_RS07200	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BJG89_RS07205	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BJG89_RS07210	COG0022	dehydrogenase e1 component
BJG89_RS07215	COG0508	dehydrogenase complex catalyzes the overall conversion of
BJG89_RS07225	COG4129	membrane
BJG89_RS07230	COG2195	Cleaves the N-terminal amino acid of tripeptides
BJG89_RS07240	COG0366	Alpha amylase catalytic
BJG89_RS07250	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BJG89_RS07255	COG1234	tRNA 3'-trailer cleavage
BJG89_RS07260	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BJG89_RS07270	COG0667	Aldo Keto reductase
BJG89_RS07275	COG0494	nUDIX hydrolase
BJG89_RS07280	COG0735	belongs to the Fur family
BJG89_RS07285	COG4974	Belongs to the 'phage' integrase family
BJG89_RS07295	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
BJG89_RS07300	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
BJG89_RS07305	COG1187	pseudouridine synthase activity
BJG89_RS07310	COG0745	RESPONSE REGULATOR receiver
BJG89_RS07325	COG1141	Ferredoxin
BJG89_RS07335	COG0514	ATP-dependent DNA helicase (RecQ)
BJG89_RS07345	COG0492	ferredoxin-NADP+ reductase activity
BJG89_RS07350	COG0252	asparaginase activity
BJG89_RS07355	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
BJG89_RS07360	COG0539	negative regulation of cytoplasmic translation
BJG89_RS07365	COG1160	GTP binding
BJG89_RS07370	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
BJG89_RS07385	COG2226	methyltransferase
BJG89_RS07390	COG0142	geranyltranstransferase activity
BJG89_RS07395	COG0105	UTP biosynthetic process
BJG89_RS07400	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
BJG89_RS07405	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
BJG89_RS07410	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
BJG89_RS07420	COG5582	Belongs to the UPF0302 family
BJG89_RS07425	COG4347	Protein of unknown function (DUF1405)
BJG89_RS07430	COG2738	Putative neutral zinc metallopeptidase
BJG89_RS07435	COG1694	Mazg nucleotide pyrophosphohydrolase
BJG89_RS07440	COG0438	transferase activity, transferring glycosyl groups
BJG89_RS07445	COG0617	tRNA 3'-terminal CCA addition
BJG89_RS07455	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BJG89_RS07455	COG1199	ATP-dependent helicase activity
BJG89_RS07460	COG0017	Asparaginyl-tRNA synthetase
BJG89_RS07465	COG3935	DnaD domain protein
BJG89_RS07470	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BJG89_RS07480	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BJG89_RS07480	COG4499	WXG100 protein secretion system (Wss), protein YukC
BJG89_RS07485	COG3331	DNA recombination
BJG89_RS07495	COG4474	Belongs to the UPF0398 family
BJG89_RS07500	COG3599	regulation of cell shape
BJG89_RS07510	COG0116	Belongs to the methyltransferase superfamily
BJG89_RS07515	COG2962	Rard protein
BJG89_RS07525	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BJG89_RS07530	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BJG89_RS07535	COG0328	RNA-DNA hybrid ribonuclease activity
BJG89_RS07545	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
BJG89_RS07555	COG1413	lyase activity
BJG89_RS07560	COG1413	lyase activity
BJG89_RS07570	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
BJG89_RS07590	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BJG89_RS07600	COG4479	Belongs to the UPF0346 family
BJG89_RS07605	COG0793	Belongs to the peptidase S41A family
BJG89_RS07615	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BJG89_RS07620	COG0671	phosphoesterase, PA-phosphatase related
BJG89_RS07625	COG0745	RESPONSE REGULATOR receiver
BJG89_RS07630	COG5002	protein histidine kinase activity
BJG89_RS07635	COG0567	Dehydrogenase, E1 component
BJG89_RS07640	COG0508	dehydrogenase complex catalyzes the overall conversion of
BJG89_RS07645	COG1396	sequence-specific DNA binding
BJG89_RS07670	COG0673	inositol 2-dehydrogenase activity
BJG89_RS07690	COG0714	Associated with various cellular activities
BJG89_RS07695	COG4548	von Willebrand factor, type A
BJG89_RS07700	COG1114	Component of the transport system for branched-chain amino acids
BJG89_RS07705	COG3853	Toxic anion resistance protein (TelA)
BJG89_RS07715	COG1254	Belongs to the acylphosphatase family
BJG89_RS07725	COG1278	Cold shock
BJG89_RS07740	COG1473	amidohydrolase
BJG89_RS07750	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
BJG89_RS07755	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BJG89_RS07760	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BJG89_RS07765	COG0527	aspartate kinase activity
BJG89_RS07775	COG0488	(ABC) transporter
BJG89_RS07780	COG2996	Protein conserved in bacteria
BJG89_RS07785	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BJG89_RS07790	COG0573	inorganic phosphate transmembrane transporter activity
BJG89_RS07795	COG0581	inorganic phosphate transmembrane transporter activity
BJG89_RS07800	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BJG89_RS07805	COG0704	Plays a role in the regulation of phosphate uptake
BJG89_RS07810	COG1164	Oligoendopeptidase f
BJG89_RS07825	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BJG89_RS07830	COG0450	alkyl hydroperoxide reductase
BJG89_RS07840	COG2124	cytochrome p450
BJG89_RS07850	COG1012	belongs to the aldehyde dehydrogenase family
BJG89_RS07855	COG0667	Aldo Keto reductase
BJG89_RS07885	COG1063	alcohol dehydrogenase
BJG89_RS07895	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BJG89_RS07905	COG2348	transferase activity, transferring amino-acyl groups
BJG89_RS07920	COG0159	tryptophan synthase activity
BJG89_RS07925	COG0133	tryptophan synthase activity
BJG89_RS07935	COG0134	indole-3-glycerol-phosphate synthase activity
BJG89_RS07940	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BJG89_RS07945	COG0512	Glutamine amidotransferase of anthranilate synthase
BJG89_RS07950	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BJG89_RS07965	COG0287	Prephenate dehydrogenase
BJG89_RS07970	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BJG89_RS07975	COG1942	4-Oxalocrotonate Tautomerase
BJG89_RS07990	COG1879	ABC-type sugar transport system periplasmic component
BJG89_RS07995	COG1172	Belongs to the binding-protein-dependent transport system permease family
BJG89_RS08000	COG1129	ABC transporter
BJG89_RS08005	COG1869	D-ribose catabolic process
BJG89_RS08010	COG1609	Transcriptional regulator
BJG89_RS08020	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
BJG89_RS08020	COG0392	lysyltransferase activity
BJG89_RS08025	COG0628	permease
BJG89_RS08030	COG1115	amino acid carrier protein
BJG89_RS08035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BJG89_RS08045	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
BJG89_RS08050	COG4841	protein insertion into membrane
BJG89_RS08055	COG0824	Thioesterase
BJG89_RS08060	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
BJG89_RS08065	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BJG89_RS08070	COG1970	mechanosensitive ion channel activity
BJG89_RS08075	COG0419	ATPase involved in DNA repair
BJG89_RS08080	COG0420	3'-5' exonuclease activity
BJG89_RS08085	COG4846	Membrane protein involved in cytochrome C biogenesis
BJG89_RS08145	COG2856	Zn peptidase
BJG89_RS08150	COG0582	viral genome integration into host DNA
BJG89_RS08160	COG3763	UPF0154 protein
BJG89_RS08180	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
BJG89_RS08190	COG0516	GMP reductase activity
BJG89_RS08195	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
BJG89_RS08200	COG0267	Belongs to the bacterial ribosomal protein bL33 family
BJG89_RS08210	COG0753	catalase activity
BJG89_RS08215	COG0833	amino acid
BJG89_RS08225	COG1522	sequence-specific DNA binding
BJG89_RS08230	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
BJG89_RS08250	COG0561	phosphatase activity
BJG89_RS08255	COG0083	homoserine kinase activity
BJG89_RS08260	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
BJG89_RS08265	COG0460	homoserine dehydrogenase
BJG89_RS08270	COG0527	aspartate kinase activity
BJG89_RS08290	COG1525	nuclease
BJG89_RS08325	COG0174	glutamine synthetase
BJG89_RS08330	COG0789	Transcriptional regulator
BJG89_RS08335	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
BJG89_RS08340	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BJG89_RS08345	COG0386	Belongs to the glutathione peroxidase family
BJG89_RS08350	COG1923	regulation of RNA biosynthetic process
BJG89_RS08355	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
BJG89_RS08365	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
BJG89_RS08370	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
BJG89_RS08375	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BJG89_RS08380	COG1619	proteins homologs of microcin C7 resistance protein MccF
BJG89_RS08390	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
BJG89_RS08395	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
BJG89_RS08405	COG4550	Control of competence regulator ComK, YlbF/YmcA
BJG89_RS08410	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BJG89_RS08420	COG0492	ferredoxin-NADP+ reductase activity
BJG89_RS08425	COG1959	2 iron, 2 sulfur cluster binding
BJG89_RS08435	COG1013	pyruvate-flavodoxin oxidoreductase activity
BJG89_RS08440	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
BJG89_RS08440	COG0674	pyruvate-flavodoxin oxidoreductase activity
BJG89_RS08445	COG1692	metallophosphoesterase
BJG89_RS08455	COG1418	mRNA catabolic process
BJG89_RS08460	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
BJG89_RS08465	COG1058	Belongs to the CinA family
BJG89_RS08465	COG1546	Belongs to the CinA family
BJG89_RS08485	COG0300	oxidoreductase activity
BJG89_RS08490	COG0612	Peptidase, M16
BJG89_RS08495	COG0612	Peptidase, M16
BJG89_RS08510	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BJG89_RS08515	COG1185	polyribonucleotide nucleotidyltransferase activity
BJG89_RS08520	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
BJG89_RS08525	COG0196	riboflavin kinase activity
BJG89_RS08530	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
BJG89_RS08535	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
BJG89_RS08550	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
BJG89_RS08555	COG1358	cellular component organization or biogenesis
BJG89_RS08560	COG2740	Nucleic-acid-binding protein implicated in transcription termination
BJG89_RS08565	COG0195	Participates in both transcription termination and antitermination
BJG89_RS08570	COG0779	Required for maturation of 30S ribosomal subunits
BJG89_RS08575	COG2176	DNA-directed DNA polymerase activity
BJG89_RS08580	COG0442	prolyl-tRNA aminoacylation
BJG89_RS08590	COG4589	Belongs to the CDS family
BJG89_RS08595	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
BJG89_RS08600	COG0233	cytoplasmic translational termination
BJG89_RS08605	COG0528	UMP kinase activity
BJG89_RS08610	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
BJG89_RS08615	COG0052	Belongs to the universal ribosomal protein uS2 family
BJG89_RS08620	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
BJG89_RS08625	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
BJG89_RS08630	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
BJG89_RS08635	COG4974	Belongs to the 'phage' integrase family
BJG89_RS08640	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
BJG89_RS08645	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BJG89_RS08650	COG0758	DNA mediated transformation
BJG89_RS08660	COG0045	succinate-CoA ligase (ADP-forming) activity
BJG89_RS08665	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BJG89_RS08675	COG4485	Bacterial membrane protein, YfhO
BJG89_RS08685	COG0335	large ribosomal subunit rRNA binding
BJG89_RS08690	COG0336	Belongs to the RNA methyltransferase TrmD family
BJG89_RS08695	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
BJG89_RS08700	COG0228	four-way junction DNA binding
BJG89_RS08705	COG1028	Short-chain dehydrogenase reductase Sdr
BJG89_RS08720	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BJG89_RS08725	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
BJG89_RS08730	COG0552	protein localization to endoplasmic reticulum
BJG89_RS08735	COG1196	nuclear chromosome segregation
BJG89_RS08740	COG0571	ribonuclease III activity
BJG89_RS08745	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BJG89_RS08750	COG1028	Short-chain dehydrogenase reductase Sdr
BJG89_RS08760	COG0416	fatty acid biosynthetic process
BJG89_RS08765	COG1349	DNA-binding transcription factor activity
BJG89_RS08780	COG1760	l-serine dehydratase
BJG89_RS08785	COG1760	l-serine dehydratase
BJG89_RS08795	COG1461	Dihydroxyacetone kinase
BJG89_RS08800	COG1302	Protein conserved in bacteria
BJG89_RS08805	COG0227	Belongs to the bacterial ribosomal protein bL28 family
BJG89_RS08810	COG1564	THIamine pyrophosphokinase
BJG89_RS08815	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BJG89_RS08820	COG1162	GTPase activity
BJG89_RS08830	COG0631	protein serine/threonine phosphatase activity
BJG89_RS08835	COG0820	rRNA (adenine-C2-)-methyltransferase activity
BJG89_RS08840	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BJG89_RS08840	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BJG89_RS08845	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BJG89_RS08850	COG0242	peptide deformylase activity
BJG89_RS08865	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
BJG89_RS08870	COG1473	amidohydrolase
BJG89_RS08895	COG1028	Short-chain dehydrogenase reductase Sdr
BJG89_RS08915	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BJG89_RS08920	COG1388	LysM domain
BJG89_RS08920	COG5632	N-Acetylmuramoyl-L-alanine amidase
BJG89_RS08945	COG5434	Belongs to the glycosyl hydrolase 28 family
BJG89_RS08945	COG4632	Exopolysaccharide biosynthesis protein
BJG89_RS09015	COG0740	serine-type endopeptidase activity
BJG89_RS09135	COG1484	DNA-dependent DNA replication
BJG89_RS09230	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BJG89_RS09235	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BJG89_RS09240	COG1758	RNA polymerase activity
BJG89_RS09245	COG0194	GDP metabolic process
BJG89_RS09260	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BJG89_RS09270	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
BJG89_RS09275	COG0284	orotidine-5'-phosphate decarboxylase activity
BJG89_RS09280	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
BJG89_RS09285	COG0505	Belongs to the CarA family
BJG89_RS09295	COG0540	Belongs to the ATCase OTCase family
BJG89_RS09300	COG2233	PERMEase
BJG89_RS09305	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
BJG89_RS09310	COG0564	pseudouridine synthase activity
BJG89_RS09315	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
BJG89_RS09325	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
BJG89_RS09330	COG3599	regulation of cell shape
BJG89_RS09340	COG0762	integral membrane protein
BJG89_RS09345	COG1799	cell septum assembly
BJG89_RS09350	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
BJG89_RS09355	COG1496	oxidoreductase activity
BJG89_RS09360	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BJG89_RS09365	COG0849	cell division
BJG89_RS09370	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
BJG89_RS09375	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
BJG89_RS09380	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BJG89_RS09385	COG0768	penicillin binding
BJG89_RS09390	COG4839	cell division protein FtsL
BJG89_RS09395	COG0275	rRNA processing
BJG89_RS09400	COG2001	Belongs to the MraZ family
BJG89_RS09405	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
BJG89_RS09410	COG0454	-acetyltransferase
BJG89_RS09415	COG1011	Hydrolase
BJG89_RS09435	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BJG89_RS09460	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
BJG89_RS09465	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BJG89_RS09470	COG1053	succinate dehydrogenase
BJG89_RS09475	COG2009	succinate dehydrogenase
BJG89_RS09480	COG0322	excinuclease ABC activity
BJG89_RS09485	COG3118	belongs to the thioredoxin family
BJG89_RS09490	COG1193	negative regulation of DNA recombination
BJG89_RS09495	COG1796	DNA polymerase
BJG89_RS09495	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
BJG89_RS09505	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
BJG89_RS09510	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BJG89_RS09515	COG0072	phenylalanine-tRNA ligase activity
BJG89_RS09520	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
BJG89_RS09525	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BJG89_RS09535	COG0333	Belongs to the bacterial ribosomal protein bL32 family
BJG89_RS09545	COG1323	Belongs to the UPF0348 family
BJG89_RS09555	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
BJG89_RS09560	COG0742	ribosomal rna small subunit methyltransferase
BJG89_RS09570	COG4471	UPF0298 protein
BJG89_RS09575	COG0584	glycerophosphoryl diester phosphodiesterase
BJG89_RS09580	COG3679	Belongs to the UPF0342 family
BJG89_RS09595	COG0109	protoheme IX farnesyltransferase activity
BJG89_RS09600	COG1612	heme a metabolic process
BJG89_RS09610	COG0772	Belongs to the SEDS family
BJG89_RS09615	COG4838	Belongs to the UPF0358 family
BJG89_RS09620	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BJG89_RS09625	COG4896	Protein conserved in bacteria
BJG89_RS09630	COG1217	gtp-binding protein TYPA
BJG89_RS09640	COG0483	inositol monophosphate 1-phosphatase activity
BJG89_RS09645	COG4493	Belongs to the UPF0637 family
BJG89_RS09655	COG1914	H( )-stimulated, divalent metal cation uptake system
BJG89_RS09675	COG1176	ABC-type spermidine putrescine transport system, permease component I
BJG89_RS09685	COG4476	Belongs to the UPF0223 family
BJG89_RS09705	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BJG89_RS09715	COG0242	peptide deformylase activity
BJG89_RS09725	COG5503	Protein of unknown function (DUF1447)
BJG89_RS09730	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BJG89_RS09735	COG0569	domain protein
BJG89_RS09740	COG1294	oxidase, subunit
BJG89_RS09745	COG1271	oxidase subunit
BJG89_RS09755	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BJG89_RS09760	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BJG89_RS09770	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
BJG89_RS09785	COG4172	Belongs to the ABC transporter superfamily
BJG89_RS09790	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
BJG89_RS09795	COG0151	Belongs to the GarS family
BJG89_RS09800	COG0138	bifunctional purine biosynthesis protein purh
BJG89_RS09810	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
BJG89_RS09820	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BJG89_RS09825	COG0047	phosphoribosylformylglycinamidine synthase activity
BJG89_RS09830	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BJG89_RS09835	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
BJG89_RS09840	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
BJG89_RS09845	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
BJG89_RS09850	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
BJG89_RS09860	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BJG89_RS09865	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BJG89_RS09870	COG1845	cytochrome c oxidase, subunit III
BJG89_RS09875	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
BJG89_RS09890	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BJG89_RS09895	COG1316	TRANSCRIPTIONal
BJG89_RS09920	COG3594	Acyltransferase
BJG89_RS09925	COG0436	Aminotransferase
BJG89_RS09935	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
BJG89_RS09940	COG2267	carboxylic ester hydrolase activity
BJG89_RS09945	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
BJG89_RS09950	COG1169	isochorismate synthase
BJG89_RS09955	COG1575	Belongs to the MenA family. Type 1 subfamily
BJG89_RS09965	COG2314	TM2 domain
BJG89_RS09990	COG4903	ComK protein
BJG89_RS10005	COG4873	Protein conserved in bacteria
BJG89_RS10015	COG0737	Belongs to the 5'-nucleotidase family
BJG89_RS10020	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BJG89_RS10025	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BJG89_RS10030	COG0861	Integral membrane protein TerC family
BJG89_RS10035	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
BJG89_RS10045	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BJG89_RS10050	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BJG89_RS10055	COG2814	Major facilitator Superfamily
BJG89_RS10060	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
BJG89_RS10065	COG2382	esterase
BJG89_RS10070	COG1115	amino acid carrier protein
BJG89_RS10075	COG0628	permease
BJG89_RS10085	COG0569	domain protein
BJG89_RS10085	COG0475	glutathione-regulated potassium exporter activity
BJG89_RS10090	COG2239	Acts as a magnesium transporter
BJG89_RS10095	COG0564	pseudouridine synthase activity
BJG89_RS10100	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BJG89_RS10105	COG2357	RelA SpoT domain protein
BJG89_RS10115	COG4116	CYTH
BJG89_RS10120	COG2346	COG2346, Truncated hemoglobins
BJG89_RS10125	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
BJG89_RS10130	COG1164	Oligoendopeptidase f
BJG89_RS10145	COG4862	establishment of competence for transformation
BJG89_RS10150	COG1393	Belongs to the ArsC family
BJG89_RS10155	COG0180	Tryptophanyl-tRNA synthetase
BJG89_RS10160	COG4166	transmembrane transport
BJG89_RS10165	COG4608	Belongs to the ABC transporter superfamily
BJG89_RS10170	COG0444	Belongs to the ABC transporter superfamily
BJG89_RS10175	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BJG89_RS10180	COG0601	transmembrane transport
BJG89_RS10200	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BJG89_RS10240	COG0561	phosphatase activity
BJG89_RS10245	COG0446	pyridine nucleotide-disulphide oxidoreductase
BJG89_RS10265	COG0179	Fumarylacetoacetate (FAA) hydrolase
BJG89_RS10270	COG2311	Membrane
BJG89_RS10275	COG1074	ATP-dependent DNA helicase activity
BJG89_RS10280	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
BJG89_RS10295	COG0398	Pfam SNARE associated Golgi protein
BJG89_RS10300	COG0166	Belongs to the GPI family
BJG89_RS10305	COG0137	argininosuccinate synthase activity
BJG89_RS10310	COG0165	Argininosuccinate lyase
BJG89_RS10315	COG0584	glycerophosphoryl diester phosphodiesterase
BJG89_RS10325	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BJG89_RS10330	COG1902	pentaerythritol trinitrate reductase activity
BJG89_RS10335	COG1098	S1 RNA binding domain
BJG89_RS10340	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BJG89_RS10350	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BJG89_RS10350	COG2111	Na H antiporter
BJG89_RS10355	COG2111	Na H antiporter
BJG89_RS10360	COG1006	Multisubunit Na H antiporter MnhC subunit
BJG89_RS10365	COG0651	ATP synthesis coupled electron transport
BJG89_RS10370	COG1863	multisubunit Na H antiporter MnhE subunit
BJG89_RS10375	COG2212	antiporter activity
BJG89_RS10380	COG1320	monovalent cation:proton antiporter activity
BJG89_RS10390	COG2050	protein possibly involved in aromatic compounds catabolism
BJG89_RS10395	COG2056	Na+-H+ antiporter family
BJG89_RS10400	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
BJG89_RS10405	COG1252	NADH dehydrogenase
BJG89_RS10410	COG0316	Belongs to the HesB IscA family
BJG89_RS10415	COG4844	belongs to the
BJG89_RS10420	COG1252	NADH dehydrogenase
BJG89_RS10425	COG4837	Protein of unknown function (DUF1462)
BJG89_RS10430	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
BJG89_RS10435	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
BJG89_RS10440	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BJG89_RS10445	COG1696	Membrane protein involved in D-alanine export
BJG89_RS10450	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BJG89_RS10460	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BJG89_RS10465	COG0647	UMP catabolic process
BJG89_RS10470	COG2445	Protein of unknown function DUF86
BJG89_RS10480	COG4470	Protein conserved in bacteria
BJG89_RS10485	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
BJG89_RS10490	COG0737	Belongs to the 5'-nucleotidase family
BJG89_RS10495	COG0730	response to heat
BJG89_RS10500	COG1801	Protein of unknown function DUF72
BJG89_RS10505	COG2070	2-Nitropropane dioxygenase
BJG89_RS10510	COG1253	flavin adenine dinucleotide binding
BJG89_RS10565	COG4632	Exopolysaccharide biosynthesis protein
BJG89_RS10565	COG5434	Belongs to the glycosyl hydrolase 28 family
BJG89_RS10585	COG5412	phage tail tape measure protein
BJG89_RS10585	COG3953	SLT domain
BJG89_RS10640	COG0740	serine-type endopeptidase activity
BJG89_RS10760	COG1484	DNA-dependent DNA replication
BJG89_RS10835	COG0719	Fe-S assembly protein
BJG89_RS10840	COG0822	iron-sulfur transferase activity
BJG89_RS10850	COG0719	Fe-S assembly protein
BJG89_RS10855	COG0396	ATPase activity
BJG89_RS10865	COG1253	flavin adenine dinucleotide binding
BJG89_RS10870	COG1464	Belongs to the NlpA lipoprotein family
BJG89_RS10875	COG2011	ABC-type metal ion transport system permease component
BJG89_RS10880	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BJG89_RS10885	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BJG89_RS10890	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
BJG89_RS10895	COG0509	glycine decarboxylation via glycine cleavage system
BJG89_RS10900	COG1393	Belongs to the ArsC family
BJG89_RS10905	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BJG89_RS10915	COG0710	3-dehydroquinate dehydratase activity
BJG89_RS10920	COG1764	response to oxidative stress
BJG89_RS10945	COG2314	TM2 domain
BJG89_RS10985	COG0346	lactoylglutathione lyase activity
BJG89_RS11020	COG1288	antiporter activity
BJG89_RS11025	COG1028	Short-chain dehydrogenase reductase Sdr
BJG89_RS11040	COG0584	glycerophosphoryl diester phosphodiesterase
BJG89_RS11060	COG1051	belongs to the nudix hydrolase family
BJG89_RS11095	COG1525	nuclease
BJG89_RS11110	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
BJG89_RS11115	COG0557	exoribonuclease II activity
BJG89_RS11120	COG1647	Serine aminopeptidase, S33
BJG89_RS11125	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BJG89_RS11135	COG0148	phosphopyruvate hydratase activity
BJG89_RS11140	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
BJG89_RS11145	COG0149	triose-phosphate isomerase activity
BJG89_RS11150	COG0126	phosphoglycerate kinase activity
BJG89_RS11155	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BJG89_RS11180	COG1090	epimerase
BJG89_RS11185	COG0740	serine-type endopeptidase activity
BJG89_RS11200	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BJG89_RS11205	COG1481	regulation of sporulation
BJG89_RS11210	COG0391	Required for morphogenesis under gluconeogenic growth conditions
BJG89_RS11215	COG1660	Displays ATPase and GTPase activities
BJG89_RS11220	COG0492	ferredoxin-NADP+ reductase activity
BJG89_RS11230	COG0110	maltose O-acetyltransferase activity
BJG89_RS11235	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
BJG89_RS11240	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
BJG89_RS11245	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BJG89_RS11250	COG0556	nucleotide-excision repair
BJG89_RS11265	COG3942	CHAP domain
BJG89_RS11265	COG1388	LysM domain
BJG89_RS11275	COG0653	protein targeting
BJG89_RS11280	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
BJG89_RS11285	COG1040	competence protein
BJG89_RS11290	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
BJG89_RS11300	COG1739	Uncharacterized protein family UPF0029
BJG89_RS11305	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BJG89_RS11310	COG2199	diguanylate cyclase activity
BJG89_RS11325	COG2195	Cleaves the N-terminal amino acid of tripeptides
BJG89_RS11330	COG1929	Belongs to the glycerate kinase type-1 family
BJG89_RS11350	COG0812	UDP-N-acetylmuramate dehydrogenase activity
BJG89_RS11365	COG4607	ABC-type enterochelin transport system periplasmic component
BJG89_RS11370	COG4604	ABC transporter, ATP-binding protein
BJG89_RS11375	COG4605	iron ion homeostasis
BJG89_RS11380	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BJG89_RS11385	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BJG89_RS11390	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BJG89_RS11395	COG1780	Probably involved in ribonucleotide reductase function
BJG89_RS11405	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
BJG89_RS11410	COG3104	oligopeptide transport
BJG89_RS11415	COG3104	oligopeptide transport
BJG89_RS11420	COG1597	lipid kinase activity
BJG89_RS11430	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BJG89_RS11435	COG1174	glycine betaine transport
BJG89_RS11445	COG0514	ATP-dependent DNA helicase (RecQ)
BJG89_RS11450	COG0488	(ABC) transporter
BJG89_RS11460	COG1368	sulfuric ester hydrolase activity
BJG89_RS11490	COG0512	Glutamine amidotransferase of anthranilate synthase
BJG89_RS11495	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
BJG89_RS11500	COG0720	synthase
BJG89_RS11505	COG0602	queuosine metabolic process
BJG89_RS11520	COG0463	Glycosyl transferase, family 2
BJG89_RS11525	COG0656	L-ascorbic acid biosynthetic process
BJG89_RS11530	COG1253	flavin adenine dinucleotide binding
BJG89_RS11535	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BJG89_RS11540	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BJG89_RS11540	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BJG89_RS11540	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BJG89_RS11545	COG1105	Belongs to the carbohydrate kinase PfkB family
BJG89_RS11550	COG1349	DNA-binding transcription factor activity
BJG89_RS11555	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BJG89_RS11560	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BJG89_RS11590	COG0039	L-malate dehydrogenase activity
BJG89_RS11595	COG0586	Pfam SNARE associated Golgi protein
BJG89_RS11605	COG4989	oxidoreductase activity
BJG89_RS11620	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
BJG89_RS11625	COG4988	ABC transporter
BJG89_RS11630	COG1968	undecaprenyl-diphosphatase activity
BJG89_RS11640	COG1671	Belongs to the UPF0178 family
BJG89_RS11645	COG1611	Belongs to the LOG family
BJG89_RS11650	COG1279	arginine transmembrane transporter activity
BJG89_RS11655	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BJG89_RS11685	COG2814	Major facilitator Superfamily
BJG89_RS11690	COG2839	Protein conserved in bacteria
BJG89_RS11695	COG2814	Major facilitator Superfamily
BJG89_RS11700	COG0583	DNA-binding transcription factor activity
BJG89_RS11710	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
BJG89_RS11720	COG0217	transcriptional regulatory protein
BJG89_RS11730	COG1388	LysM domain
BJG89_RS11730	COG3942	CHAP domain
BJG89_RS11735	COG0306	phosphate transporter
BJG89_RS11740	COG1392	Phosphate transport regulator
BJG89_RS11745	COG2205	protein histidine kinase activity
BJG89_RS11750	COG0745	RESPONSE REGULATOR receiver
BJG89_RS11755	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BJG89_RS11770	COG4555	ABC transporter
BJG89_RS11790	COG3949	Membrane
BJG89_RS11800	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
BJG89_RS11810	COG2376	Dihydroxyacetone kinase
BJG89_RS11815	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BJG89_RS11820	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BJG89_RS11825	COG1120	ATPase activity
BJG89_RS11830	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BJG89_RS11835	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BJG89_RS11840	COG1132	(ABC) transporter
BJG89_RS11850	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
BJG89_RS11860	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
BJG89_RS11865	COG1682	transport, permease protein
BJG89_RS11870	COG1134	teichoic acid transport
BJG89_RS11875	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
BJG89_RS11885	COG1321	iron dependent repressor
BJG89_RS11895	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BJG89_RS11900	COG0803	Belongs to the bacterial solute-binding protein 9 family
BJG89_RS11910	COG1320	monovalent cation:proton antiporter activity
BJG89_RS11915	COG2212	antiporter activity
BJG89_RS11920	COG1863	multisubunit Na H antiporter MnhE subunit
BJG89_RS11925	COG0651	ATP synthesis coupled electron transport
BJG89_RS11930	COG1006	Multisubunit Na H antiporter MnhC subunit
BJG89_RS11935	COG2111	Na H antiporter
BJG89_RS11940	COG2111	Na H antiporter
BJG89_RS11940	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BJG89_RS11945	COG4974	Belongs to the 'phage' integrase family
BJG89_RS11995	COG2267	carboxylic ester hydrolase activity
BJG89_RS12000	COG0546	phosphoglycolate phosphatase activity
BJG89_RS12005	COG4139	cobalamin transport
BJG89_RS12010	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BJG89_RS12015	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BJG89_RS12020	COG0018	arginyl-trna synthetase
BJG89_RS12035	COG1078	dGTPase activity
BJG89_RS12040	COG0456	acetyltransferase
BJG89_RS12045	COG0655	NAD(P)H dehydrogenase (quinone) activity
BJG89_RS12050	COG0667	Aldo Keto reductase
BJG89_RS12065	COG1028	Short-chain dehydrogenase reductase Sdr
BJG89_RS12070	COG4844	belongs to the
BJG89_RS12075	COG1082	Xylose isomerase domain protein TIM barrel
BJG89_RS12080	COG0673	inositol 2-dehydrogenase activity
BJG89_RS12090	COG0673	inositol 2-dehydrogenase activity
BJG89_RS12100	COG1263	PTS System
BJG89_RS12100	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BJG89_RS12120	COG0095	Lipoate-protein ligase
BJG89_RS12125	COG0280	phosphate acetyltransferase
BJG89_RS12130	COG3253	May function as heme-dependent peroxidase
BJG89_RS12165	COG2363	Small membrane protein
BJG89_RS12175	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
BJG89_RS12180	COG0351	phosphomethylpyrimidine kinase
BJG89_RS12210	COG0183	Belongs to the thiolase family
BJG89_RS12215	COG0318	PFAM AMP-dependent synthetase and ligase
BJG89_RS12225	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
BJG89_RS12230	COG0363	glucosamine-6-phosphate deaminase activity
BJG89_RS12240	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BJG89_RS12245	COG1469	GTP cyclohydrolase I activity
BJG89_RS12260	COG0431	NADPH-dependent FMN reductase
BJG89_RS12265	COG0561	phosphatase activity
BJG89_RS12275	COG1428	Deoxynucleoside kinase
BJG89_RS12280	COG1428	Deoxynucleoside kinase
BJG89_RS12290	COG0546	phosphoglycolate phosphatase activity
BJG89_RS12295	COG4297	protein containing double-stranded beta helix domain
BJG89_RS12300	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BJG89_RS12305	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BJG89_RS12315	COG0583	DNA-binding transcription factor activity
BJG89_RS12320	COG2814	Major facilitator Superfamily
BJG89_RS12335	COG0010	Belongs to the arginase family
BJG89_RS12340	COG1914	H( )-stimulated, divalent metal cation uptake system
BJG89_RS12350	COG1132	(ABC) transporter
BJG89_RS12355	COG1028	Short-chain dehydrogenase reductase Sdr
BJG89_RS12360	COG1312	Catalyzes the dehydration of D-mannonate
BJG89_RS12365	COG1904	glucuronate isomerase
BJG89_RS12390	COG0800	Aldolase
BJG89_RS12400	COG0583	DNA-binding transcription factor activity
BJG89_RS12430	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
BJG89_RS12455	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
BJG89_RS12460	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
BJG89_RS12480	COG1473	amidohydrolase
BJG89_RS12485	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BJG89_RS12490	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BJG89_RS12495	COG0049	tRNA binding
BJG89_RS12500	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
BJG89_RS12510	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
BJG89_RS12515	COG0085	RNA polymerase activity
BJG89_RS12520	COG2813	Specifically methylates the guanine in position
BJG89_RS12530	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
BJG89_RS12535	COG0081	regulation of translation
BJG89_RS12540	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
BJG89_RS12545	COG0250	Participates in transcription elongation, termination and antitermination
BJG89_RS12550	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BJG89_RS12555	COG0267	Belongs to the bacterial ribosomal protein bL33 family
BJG89_RS12570	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BJG89_RS12575	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
BJG89_RS12580	COG0215	cysteine-tRNA ligase activity
BJG89_RS12585	COG1045	serine acetyltransferase
BJG89_RS12590	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BJG89_RS12595	COG4956	integral membrane protein (PIN domain superfamily)
BJG89_RS12600	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
BJG89_RS12605	COG0542	response to heat
BJG89_RS12610	COG3869	Catalyzes the specific phosphorylation of arginine residues in
BJG89_RS12615	COG3880	PFAM UvrB UvrC protein
BJG89_RS12620	COG4463	regulation of RNA biosynthetic process
BJG89_RS12625	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BJG89_RS12630	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
BJG89_RS12635	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
BJG89_RS12640	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BJG89_RS12705	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
BJG89_RS12710	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BJG89_RS12730	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
BJG89_RS12735	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BJG89_RS12750	COG1098	S1 RNA binding domain
BJG89_RS12760	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
BJG89_RS12765	COG3956	TIGRFAM MazG family protein
BJG89_RS12770	COG2244	polysaccharide biosynthetic process
BJG89_RS12775	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BJG89_RS12780	COG0193	aminoacyl-tRNA hydrolase activity
BJG89_RS12785	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
BJG89_RS12790	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BJG89_RS12795	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
BJG89_RS12800	COG2088	sporulation resulting in formation of a cellular spore
BJG89_RS12805	COG0251	oxidation-reduction process
BJG89_RS12810	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BJG89_RS12815	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
BJG89_RS12820	COG4466	Protein conserved in bacteria
BJG89_RS12825	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
BJG89_RS12830	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
BJG89_RS12835	COG0084	hydrolase, TatD family'
BJG89_RS12840	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BJG89_RS12840	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BJG89_RS12845	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
BJG89_RS12850	COG2827	Endonuclease containing a URI domain
BJG89_RS12855	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
BJG89_RS12860	COG4467	Involved in initiation control of chromosome replication
BJG89_RS12865	COG1774	PSP1 C-terminal conserved region
BJG89_RS12870	COG0470	DNA polymerase III
BJG89_RS12875	COG3870	Protein conserved in bacteria
BJG89_RS12880	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
BJG89_RS12885	COG1982	Orn Lys Arg decarboxylase major
BJG89_RS12925	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
BJG89_RS12930	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
BJG89_RS12935	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BJG89_RS12950	COG2188	Transcriptional regulator
BJG89_RS12955	COG0366	Alpha amylase catalytic
BJG89_RS12960	COG1263	PTS System
BJG89_RS12960	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BJG89_RS12970	COG0493	'glutamate synthase
BJG89_RS12975	COG0070	glutamate synthase
BJG89_RS12975	COG0069	glutamate synthase activity
BJG89_RS12975	COG0067	glutamate synthase
BJG89_RS13000	COG0753	catalase activity
BJG89_RS13010	COG1316	TRANSCRIPTIONal
BJG89_RS13020	COG0772	Belongs to the SEDS family
BJG89_RS13025	COG1051	belongs to the nudix hydrolase family
BJG89_RS13035	COG3942	CHAP domain
BJG89_RS13035	COG1388	LysM domain
BJG89_RS13045	COG0129	dihydroxy-acid dehydratase activity
BJG89_RS13055	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
BJG89_RS13060	COG0733	neurotransmitter:sodium symporter activity
BJG89_RS13065	COG1114	Component of the transport system for branched-chain amino acids
BJG89_RS13070	COG5646	InterPro IPR014922
BJG89_RS13075	COG1647	Serine aminopeptidase, S33
BJG89_RS13080	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
BJG89_RS13085	COG2807	transmembrane transport
BJG89_RS13100	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
BJG89_RS13105	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
BJG89_RS13110	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
BJG89_RS13115	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
BJG89_RS13120	COG3257	ureidoglycine aminohydrolase activity
BJG89_RS13125	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BJG89_RS13135	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BJG89_RS13140	COG0406	alpha-ribazole phosphatase activity
BJG89_RS13145	COG1115	amino acid carrier protein
BJG89_RS13150	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BJG89_RS13155	COG1953	Uracil, thiamine, allantoin
BJG89_RS13160	COG2508	Transcriptional regulator
BJG89_RS13165	COG2814	Major facilitator Superfamily
BJG89_RS13170	COG2814	Major facilitator Superfamily
BJG89_RS13190	COG2140	Oxalate decarboxylase
BJG89_RS13195	COG0405	Gamma-glutamyltransferase
BJG89_RS13200	COG2233	PERMEase
BJG89_RS13240	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BJG89_RS13240	COG0519	Catalyzes the synthesis of GMP from XMP
BJG89_RS13245	COG0517	IMP dehydrogenase activity
BJG89_RS13245	COG0516	GMP reductase activity
BJG89_RS13250	COG2233	PERMEase
BJG89_RS13255	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BJG89_RS13270	COG5183	chlorophyll binding
BJG89_RS13275	COG1823	symporter activity
BJG89_RS13285	COG0778	Nitroreductase
BJG89_RS13290	COG0753	catalase activity
BJG89_RS13300	COG3279	Response regulator of the LytR AlgR family
BJG89_RS13315	COG0450	alkyl hydroperoxide reductase
BJG89_RS13320	COG3634	alkyl hydroperoxide reductase activity
BJG89_RS13335	COG0588	phosphoglycerate mutase activity
BJG89_RS13345	COG1280	lysine exporter protein (LysE YggA)
BJG89_RS13350	COG2076	Multidrug Resistance protein
BJG89_RS13355	COG2076	Multidrug Resistance protein
BJG89_RS13365	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BJG89_RS13380	COG4195	phage-related replication protein
BJG89_RS13425	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
BJG89_RS13435	COG0360	Binds together with S18 to 16S ribosomal RNA
BJG89_RS13445	COG1695	Transcriptional regulator
BJG89_RS13450	COG3479	Phenolic acid decarboxylase
BJG89_RS13455	COG0012	GTP binding
BJG89_RS13460	COG4481	Protein conserved in bacteria
BJG89_RS13465	COG0668	transmembrane transport
BJG89_RS13470	COG5609	conserved protein (DUF2294)
BJG89_RS13475	COG3002	Belongs to the UPF0753 family
BJG89_RS13480	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BJG89_RS13490	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BJG89_RS13500	COG2814	Major facilitator Superfamily
BJG89_RS13520	COG1388	LysM domain
BJG89_RS13545	COG1131	(ABC) transporter
BJG89_RS13585	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BJG89_RS13590	COG2210	Belongs to the sulfur carrier protein TusA family
BJG89_RS13595	COG1937	Protein conserved in bacteria
BJG89_RS13600	COG0730	response to heat
BJG89_RS13610	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BJG89_RS13620	COG3559	Exporter of polyketide antibiotics
BJG89_RS13625	COG1131	(ABC) transporter
BJG89_RS13655	COG0772	Belongs to the SEDS family
BJG89_RS13685	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
BJG89_RS13695	COG0529	Catalyzes the synthesis of activated sulfate
BJG89_RS13700	COG2046	Belongs to the sulfate adenylyltransferase family
BJG89_RS13705	COG0730	response to heat
BJG89_RS13720	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BJG89_RS13725	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BJG89_RS13730	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
BJG89_RS13735	COG0175	sulfate reduction
BJG89_RS13740	COG3620	sequence-specific DNA binding
BJG89_RS13765	COG1028	Short-chain dehydrogenase reductase Sdr
BJG89_RS13780	COG2311	Membrane
BJG89_RS13790	COG2188	Transcriptional regulator
BJG89_RS13795	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BJG89_RS13810	COG3964	amidohydrolase
BJG89_RS13815	COG1017	nitric oxide dioxygenase activity
BJG89_RS13815	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BJG89_RS13825	COG1475	DNA binding
BJG89_RS13835	COG0626	cystathionine gamma-synthase activity
BJG89_RS13840	COG0626	cystathionine gamma-synthase activity
BJG89_RS13845	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
BJG89_RS13845	COG0646	methionine synthase
BJG89_RS13850	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
BJG89_RS13860	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
BJG89_RS13880	COG0183	Belongs to the thiolase family
BJG89_RS13885	COG1250	3-hydroxyacyl-CoA dehydrogenase
BJG89_RS13885	COG1024	Enoyl-CoA hydratase
BJG89_RS13890	COG1960	acyl-CoA dehydrogenase activity
BJG89_RS13895	COG0318	PFAM AMP-dependent synthetase and ligase
BJG89_RS13915	COG4175	Glycine betaine
BJG89_RS13915	COG3448	diguanylate cyclase activity
BJG89_RS13920	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BJG89_RS13935	COG0561	phosphatase activity
BJG89_RS13940	COG2207	Transcriptional regulator
BJG89_RS13940	COG1917	Cupin 2, conserved barrel domain protein
BJG89_RS13945	COG0697	spore germination
BJG89_RS13955	COG1028	Short-chain dehydrogenase reductase Sdr
BJG89_RS13960	COG2239	Acts as a magnesium transporter
BJG89_RS13970	COG0531	amino acid
BJG89_RS13995	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BJG89_RS14005	COG1285	pathogenesis
BJG89_RS14020	COG3181	Tripartite tricarboxylate transporter family receptor
BJG89_RS14025	COG2271	Major facilitator Superfamily
BJG89_RS14035	COG1966	Carbon starvation protein
BJG89_RS14040	COG1475	DNA binding
BJG89_RS14045	COG0357	Ribosomal RNA small subunit methyltransferase G
BJG89_RS14050	COG0445	tRNA wobble uridine modification
BJG89_RS14055	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
BJG89_RS14060	COG0594	ribonuclease P activity
BJG89_RS14085	COG1131	(ABC) transporter
BJG89_RS14095	COG0446	pyridine nucleotide-disulphide oxidoreductase
BJG89_RS14170	COG0783	Belongs to the Dps family
BJG89_RS14175	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BJG89_RS14200	COG4716	Myosin-crossreactive antigen
BJG89_RS14205	COG1063	alcohol dehydrogenase
BJG89_RS14215	COG1607	acyl-coa hydrolase
BJG89_RS14220	COG0583	DNA-binding transcription factor activity
BJG89_RS14245	COG3586	endonuclease activity
BJG89_RS14310	COG1028	Short-chain dehydrogenase reductase Sdr
BJG89_RS14330	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BJG89_RS14335	COG1388	LysM domain
BJG89_RS14335	COG5632	N-Acetylmuramoyl-L-alanine amidase
BJG89_RS14360	COG5434	Belongs to the glycosyl hydrolase 28 family
BJG89_RS14360	COG4632	Exopolysaccharide biosynthesis protein
BJG89_RS14380	COG3953	SLT domain
BJG89_RS14380	COG5412	phage tail tape measure protein