locus-tag	class	description
STP1_RS00005	COG1114	Component of the transport system for branched-chain amino acids
STP1_RS00010	COG4548	von Willebrand factor, type A
STP1_RS00015	COG0714	Associated with various cellular activities
STP1_RS00040	COG1131	(ABC) transporter
STP1_RS00045	COG0508	dehydrogenase complex catalyzes the overall conversion of
STP1_RS00050	COG0567	Dehydrogenase, E1 component
STP1_RS00055	COG5002	protein histidine kinase activity
STP1_RS00060	COG0745	RESPONSE REGULATOR receiver
STP1_RS00065	COG0671	phosphoesterase, PA-phosphatase related
STP1_RS00070	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
STP1_RS00080	COG0793	Belongs to the peptidase S41A family
STP1_RS00090	COG2190	(PTS) system
STP1_RS00095	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
STP1_RS00125	COG1413	lyase activity
STP1_RS00130	COG1413	lyase activity
STP1_RS00135	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
STP1_RS00150	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
STP1_RS00155	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
STP1_RS00165	COG0116	Belongs to the methyltransferase superfamily
STP1_RS00170	COG3599	regulation of cell shape
STP1_RS00185	COG3331	DNA recombination
STP1_RS00190	COG4499	WXG100 protein secretion system (Wss), protein YukC
STP1_RS00190	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
STP1_RS00200	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
STP1_RS00205	COG3935	DnaD domain protein
STP1_RS00210	COG0017	Asparaginyl-tRNA synthetase
STP1_RS00215	COG1199	ATP-dependent helicase activity
STP1_RS00215	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
STP1_RS00220	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
STP1_RS00220	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
STP1_RS00225	COG0617	tRNA 3'-terminal CCA addition
STP1_RS00230	COG0438	transferase activity, transferring glycosyl groups
STP1_RS00235	COG1694	Mazg nucleotide pyrophosphohydrolase
STP1_RS00240	COG2738	Putative neutral zinc metallopeptidase
STP1_RS00245	COG4347	Protein of unknown function (DUF1405)
STP1_RS00250	COG5582	Belongs to the UPF0302 family
STP1_RS00260	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
STP1_RS00265	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
STP1_RS00270	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
STP1_RS00285	COG2226	methyltransferase
STP1_RS00300	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
STP1_RS00305	COG1160	GTP binding
STP1_RS00310	COG0539	negative regulation of cytoplasmic translation
STP1_RS00325	COG0492	ferredoxin-NADP+ reductase activity
STP1_RS00335	COG0514	ATP-dependent DNA helicase (RecQ)
STP1_RS00345	COG1141	Ferredoxin
STP1_RS00360	COG0745	RESPONSE REGULATOR receiver
STP1_RS00365	COG1187	pseudouridine synthase activity
STP1_RS00370	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
STP1_RS00375	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
STP1_RS00385	COG4974	Belongs to the 'phage' integrase family
STP1_RS00390	COG0735	belongs to the Fur family
STP1_RS00395	COG0494	nUDIX hydrolase
STP1_RS00400	COG0667	Aldo Keto reductase
STP1_RS00405	COG1028	Short-chain dehydrogenase reductase Sdr
STP1_RS00410	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
STP1_RS00415	COG1234	tRNA 3'-trailer cleavage
STP1_RS00420	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
STP1_RS00430	COG0366	Alpha amylase catalytic
STP1_RS00435	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
STP1_RS00440	COG2195	Cleaves the N-terminal amino acid of tripeptides
STP1_RS00445	COG4129	membrane
STP1_RS00455	COG0508	dehydrogenase complex catalyzes the overall conversion of
STP1_RS00460	COG0022	dehydrogenase e1 component
STP1_RS00465	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
STP1_RS00470	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
STP1_RS00475	COG0497	DNA recombination
STP1_RS00480	COG1438	arginine binding
STP1_RS00490	COG1722	exodeoxyribonuclease VII activity
STP1_RS00500	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
STP1_RS00505	COG1302	Protein conserved in bacteria
STP1_RS00510	COG0439	Biotin carboxylase
STP1_RS00515	COG0511	ligase activity, forming carbon-carbon bonds
STP1_RS00520	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
STP1_RS00525	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
STP1_RS00530	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
STP1_RS00535	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
STP1_RS00540	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
STP1_RS00545	COG0006	proline dipeptidase activity
STP1_RS00560	COG0095	Lipoate-protein ligase
STP1_RS00565	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
STP1_RS00580	COG0404	The glycine cleavage system catalyzes the degradation of glycine
STP1_RS00585	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
STP1_RS00600	COG4537	Required for transformation and DNA binding
STP1_RS00605	COG1459	type II secretion system
STP1_RS00610	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
STP1_RS00615	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
STP1_RS00620	COG0011	TIGRFAM Protein of
STP1_RS00625	COG1940	carbohydrate kinase activity
STP1_RS00630	COG4483	Protein conserved in bacteria
STP1_RS00640	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
STP1_RS00645	COG0267	Belongs to the bacterial ribosomal protein bL33 family
STP1_RS00650	COG0768	penicillin binding
STP1_RS00665	COG1108	ABC-type Mn2 Zn2 transport systems permease components
STP1_RS00670	COG1121	(ABC) transporter
STP1_RS00675	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
STP1_RS00680	COG0513	Belongs to the DEAD box helicase family
STP1_RS00685	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
STP1_RS00690	COG2384	SAM-dependent methyltransferase
STP1_RS00695	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
STP1_RS00700	COG0358	DNA primase activity
STP1_RS00705	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
STP1_RS00710	COG0517	IMP dehydrogenase activity
STP1_RS00715	COG0423	glycine-tRNA ligase activity
STP1_RS00720	COG1381	Involved in DNA repair and RecF pathway recombination
STP1_RS00725	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
STP1_RS00745	COG1702	phosphate starvation-inducible protein PhoH
STP1_RS00755	COG4864	UPF0365 protein
STP1_RS00760	COG1030	water channel activity
STP1_RS00770	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
STP1_RS00775	COG1385	rRNA (uridine-N3-)-methyltransferase activity
STP1_RS00785	COG0484	heat shock protein binding
STP1_RS00790	COG0443	Heat shock 70 kDa protein
STP1_RS00795	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
STP1_RS00805	COG0635	Involved in the biosynthesis of porphyrin-containing compound
STP1_RS00810	COG0481	GTPase activity
STP1_RS00815	COG0268	Binds directly to 16S ribosomal RNA
STP1_RS00820	COG1466	dna polymerase III delta subunit
STP1_RS00825	COG2333	competence protein COMEC
STP1_RS00825	COG0658	competence protein
STP1_RS00830	COG2131	deaminase
STP1_RS00835	COG1596	polysaccharide export
STP1_RS00835	COG1555	photosystem II stabilization
STP1_RS00840	COG4106	trans-aconitate 2-methyltransferase activity
STP1_RS00845	COG0799	negative regulation of ribosome biogenesis
STP1_RS00850	COG1713	HD superfamily hydrolase involved in NAD metabolism
STP1_RS00855	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
STP1_RS00860	COG1534	Rna-binding protein
STP1_RS00865	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
STP1_RS00870	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
STP1_RS00875	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
STP1_RS00880	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
STP1_RS00885	COG1914	H( )-stimulated, divalent metal cation uptake system
STP1_RS00890	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
STP1_RS00895	COG0439	Biotin carboxylase
STP1_RS00900	COG0511	ligase activity, forming carbon-carbon bonds
STP1_RS00905	COG1984	allophanate hydrolase subunit 2
STP1_RS00910	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
STP1_RS00915	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
STP1_RS00920	COG0572	uridine kinase
STP1_RS00925	COG0826	peptidase U32
STP1_RS00930	COG0826	peptidase U32
STP1_RS00935	COG4122	O-methyltransferase activity
STP1_RS00940	COG3906	Belongs to the UPF0473 family
STP1_RS00945	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
STP1_RS00950	COG4472	Bacterial protein of unknown function (DUF965)
STP1_RS00960	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
STP1_RS00970	COG0482	sulfurtransferase activity
STP1_RS00975	COG1104	cysteine desulfurase activity
STP1_RS00980	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
STP1_RS00990	COG1959	2 iron, 2 sulfur cluster binding
STP1_RS00995	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
STP1_RS01000	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
STP1_RS01005	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
STP1_RS01015	COG0860	N-Acetylmuramoyl-L-alanine amidase
STP1_RS01025	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
STP1_RS01035	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
STP1_RS01035	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
STP1_RS01040	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
STP1_RS01040	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
STP1_RS01045	COG1862	Preprotein translocase
STP1_RS01055	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
STP1_RS01065	COG0632	four-way junction helicase activity
STP1_RS01070	COG4492	Belongs to the UPF0735 family
STP1_RS01075	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
STP1_RS01080	COG0211	Belongs to the bacterial ribosomal protein bL27 family
STP1_RS01085	COG2868	ribosomal protein
STP1_RS01090	COG0261	This protein binds to 23S rRNA in the presence of protein L20
STP1_RS01120	COG2003	Belongs to the UPF0758 family
STP1_RS01130	COG0285	dihydrofolate synthase activity
STP1_RS01135	COG0525	valine-tRNA ligase activity
STP1_RS01140	COG2818	Glycosylase
STP1_RS01150	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
STP1_RS01155	COG0113	porphobilinogen synthase activity
STP1_RS01165	COG0181	hydroxymethylbilane synthase activity
STP1_RS01170	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
STP1_RS01180	COG0218	Necessary for normal cell division and for the maintenance of normal septation
STP1_RS01185	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
STP1_RS01190	COG0544	peptidyl-prolyl cis-trans isomerase activity
STP1_RS01200	COG4112	unkown
STP1_RS01205	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
STP1_RS01210	COG0291	Belongs to the bacterial ribosomal protein bL35 family
STP1_RS01215	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
STP1_RS01220	COG0833	amino acid
STP1_RS01230	COG1484	DNA-dependent DNA replication
STP1_RS01235	COG3611	Membrane attachment protein
STP1_RS01240	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
STP1_RS01245	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
STP1_RS01250	COG0237	dephospho-CoA kinase activity
STP1_RS01255	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
STP1_RS01260	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
STP1_RS01260	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
STP1_RS01265	COG5002	protein histidine kinase activity
STP1_RS01270	COG0745	RESPONSE REGULATOR receiver
STP1_RS01275	COG0538	isocitrate dehydrogenase activity
STP1_RS01280	COG0372	Belongs to the citrate synthase family
STP1_RS01285	COG1113	amino acid transport
STP1_RS01290	COG0469	pyruvate kinase activity
STP1_RS01295	COG0205	6-phosphofructokinase activity
STP1_RS01305	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
STP1_RS01310	COG0281	malic enzyme
STP1_RS01320	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
STP1_RS01325	COG4109	DRTGG domain
STP1_RS01335	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
STP1_RS01340	COG0006	proline dipeptidase activity
STP1_RS01345	COG0686	Belongs to the AlaDH PNT family
STP1_RS01350	COG0589	response to stress
STP1_RS01355	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
STP1_RS01360	COG0827	DNA restriction-modification system
STP1_RS01365	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
STP1_RS01375	COG0301	tRNA thio-modification
STP1_RS01380	COG1104	cysteine desulfurase activity
STP1_RS01385	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
STP1_RS01390	COG1956	GAF domain-containing protein
STP1_RS01395	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
STP1_RS01400	COG0584	glycerophosphoryl diester phosphodiesterase
STP1_RS01405	COG1764	response to oxidative stress
STP1_RS01410	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
STP1_RS01415	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
STP1_RS01425	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
STP1_RS01425	COG1263	PTS System
STP1_RS01445	COG0204	Acyl-transferase
STP1_RS01450	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
STP1_RS01470	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
STP1_RS01480	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
STP1_RS01485	COG0454	-acetyltransferase
STP1_RS01495	COG1609	Transcriptional regulator
STP1_RS01500	COG1605	Chorismate mutase
STP1_RS01500	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
STP1_RS01515	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
STP1_RS01520	COG1674	ftsk spoiiie
STP1_RS01525	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
STP1_RS01530	COG4848	Belongs to the UPF0354 family
STP1_RS01535	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
STP1_RS01540	COG1363	Peptidase, m42
STP1_RS01550	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
STP1_RS01555	COG0220	tRNA (guanine-N7-)-methyltransferase activity
STP1_RS01560	COG0510	thiamine kinase activity
STP1_RS01565	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
STP1_RS01570	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
STP1_RS01580	COG1187	pseudouridine synthase activity
STP1_RS01585	COG2244	polysaccharide biosynthetic process
STP1_RS01590	COG2081	HI0933 family
STP1_RS01605	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
STP1_RS01610	COG0495	leucyl-tRNA aminoacylation
STP1_RS01615	COG2814	Major facilitator Superfamily
STP1_RS01620	COG1242	4 iron, 4 sulfur cluster binding
STP1_RS01625	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
STP1_RS01635	COG2267	carboxylic ester hydrolase activity
STP1_RS01640	COG0506	proline dehydrogenase activity
STP1_RS01645	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
STP1_RS01650	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
STP1_RS01650	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
STP1_RS01655	COG0307	riboflavin synthase, alpha
STP1_RS01660	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
STP1_RS01660	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
STP1_RS01670	COG3266	domain, Protein
STP1_RS01670	COG5632	N-Acetylmuramoyl-L-alanine amidase
STP1_RS01670	COG4193	domain, Protein
STP1_RS01695	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
STP1_RS01710	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
STP1_RS01715	COG0656	L-ascorbic acid biosynthetic process
STP1_RS01725	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
STP1_RS01735	COG1506	peptidase
STP1_RS01755	COG0318	PFAM AMP-dependent synthetase and ligase
STP1_RS01800	COG3545	Serine hydrolase
STP1_RS01805	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
STP1_RS01810	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
STP1_RS01820	COG2329	Antibiotic biosynthesis monooxygenase
STP1_RS01825	COG4473	ABC transporter
STP1_RS01830	COG1131	(ABC) transporter
STP1_RS01835	COG0537	adenosine 5'-monophosphoramidase activity
STP1_RS01850	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
STP1_RS01855	COG3481	metal-dependent phosphohydrolase, HD sub domain
STP1_RS01865	COG0420	3'-5' exonuclease activity
STP1_RS01870	COG3679	Belongs to the UPF0342 family
STP1_RS01875	COG4399	Belongs to the UPF0754 family
STP1_RS01885	COG2197	response regulator
STP1_RS01890	COG4585	Histidine kinase
STP1_RS01890	COG2203	Gaf domain
STP1_RS01895	COG0564	pseudouridine synthase activity
STP1_RS01900	COG0114	fumarate hydratase activity
STP1_RS01915	COG0363	glucosamine-6-phosphate deaminase activity
STP1_RS01925	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
STP1_RS01930	COG1126	abc transporter atp-binding protein
STP1_RS01935	COG0765	amino acid transport
STP1_RS02015	COG0735	belongs to the Fur family
STP1_RS02020	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
STP1_RS02025	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
STP1_RS02030	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
STP1_RS02035	COG4129	membrane
STP1_RS02045	COG3557	Belongs to the UPF0374 family
STP1_RS02050	COG1194	a g-specific adenine glycosylase
STP1_RS02055	COG1988	membrane-bound metal-dependent
STP1_RS02065	COG1134	teichoic acid transport
STP1_RS02065	COG1388	LysM domain
STP1_RS02080	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
STP1_RS02085	COG0693	protein deglycase activity
STP1_RS02090	COG0535	radical SAM domain protein
STP1_RS02100	COG2309	aminopeptidase activity
STP1_RS02105	COG4840	Belongs to the UPF0435 family
STP1_RS02120	COG1295	ribonuclease BN
STP1_RS02125	COG2197	response regulator
STP1_RS02145	COG0024	Methionine aminopeptidase
STP1_RS02150	COG4129	membrane
STP1_RS02165	COG1528	Iron-storage protein
STP1_RS02195	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
STP1_RS02200	COG1597	lipid kinase activity
STP1_RS02205	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
STP1_RS02220	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
STP1_RS02230	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
STP1_RS02235	COG0210	DNA helicase
STP1_RS02240	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
STP1_RS02245	COG4496	protein, YerC YecD
STP1_RS02250	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
STP1_RS02255	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
STP1_RS02260	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
STP1_RS02265	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
STP1_RS02275	COG0077	Prephenate dehydratase
STP1_RS02285	COG1335	isochorismatase
STP1_RS02290	COG1227	inorganic diphosphatase activity
STP1_RS02295	COG1012	belongs to the aldehyde dehydrogenase family
STP1_RS02300	COG2706	6-phosphogluconolactonase activity
STP1_RS02340	COG1131	(ABC) transporter
STP1_RS02355	COG1725	Transcriptional regulator
STP1_RS02405	COG3728	DNA packaging
STP1_RS02405	COG5484	DNA packaging
STP1_RS02475	COG0582	viral genome integration into host DNA
STP1_RS02480	COG0459	protein refolding
STP1_RS02485	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
STP1_RS02535	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
STP1_RS02540	COG1621	beta-fructofuranosidase activity
STP1_RS02545	COG1609	Transcriptional regulator
STP1_RS02550	COG0425	Belongs to the sulfur carrier protein TusA family
STP1_RS02555	COG2391	methyltransferase activity
STP1_RS02570	COG0488	(ABC) transporter
STP1_RS02575	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
STP1_RS02580	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
STP1_RS02585	COG0456	acetyltransferase
STP1_RS02590	COG1214	PFAM Peptidase M22, glycoprotease
STP1_RS02595	COG0802	atpase or kinase
STP1_RS02600	COG0129	dihydroxy-acid dehydratase activity
STP1_RS02605	COG0028	Belongs to the TPP enzyme family
STP1_RS02625	COG0473	3-isopropylmalate dehydrogenase activity
STP1_RS02630	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
STP1_RS02675	COG2183	response to ionizing radiation
STP1_RS02680	COG1191	sigma factor activity
STP1_RS02695	COG2208	phosphoserine phosphatase activity
STP1_RS02700	COG2337	Toxic component of a toxin-antitoxin (TA) module
STP1_RS02710	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
STP1_RS02715	COG0736	holo-[acyl-carrier-protein] synthase activity
STP1_RS02725	COG3428	Bacterial PH domain
STP1_RS02735	COG0513	Belongs to the DEAD box helicase family
STP1_RS02740	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
STP1_RS02745	COG1181	Belongs to the D-alanine--D-alanine ligase family
STP1_RS02750	COG0772	Belongs to the SEDS family
STP1_RS02760	COG1937	Protein conserved in bacteria
STP1_RS02765	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
STP1_RS02770	COG1418	mRNA catabolic process
STP1_RS02775	COG0706	membrane insertase activity
STP1_RS02780	COG0352	thiamine-phosphate diphosphorylase activity
STP1_RS02785	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
STP1_RS02795	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
STP1_RS02805	COG0629	single-stranded DNA binding
STP1_RS02815	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
STP1_RS02830	COG0355	proton-transporting ATP synthase activity, rotational mechanism
STP1_RS02835	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
STP1_RS02850	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
STP1_RS02875	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
STP1_RS02880	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
STP1_RS02890	COG4475	Protein of unknown function (DUF436)
STP1_RS02895	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
STP1_RS02900	COG0009	L-threonylcarbamoyladenylate synthase
STP1_RS02905	COG2890	protein-(glutamine-N5) methyltransferase activity
STP1_RS02915	COG1435	thymidine kinase activity
STP1_RS02920	COG0254	rRNA binding
STP1_RS02925	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
STP1_RS02930	COG1012	belongs to the aldehyde dehydrogenase family
STP1_RS02945	COG0191	fructose-bisphosphate aldolase activity
STP1_RS02955	COG0504	CTP synthase activity
STP1_RS02990	COG1854	S-ribosylhomocysteine lyase activity
STP1_RS03000	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
STP1_RS03005	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
STP1_RS03010	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
STP1_RS03015	COG0813	purine-nucleoside phosphorylase activity
STP1_RS03020	COG0783	Belongs to the Dps family
STP1_RS03040	COG1482	cell wall glycoprotein biosynthetic process
STP1_RS03045	COG0702	epimerase
STP1_RS03050	COG0640	Transcriptional regulator
STP1_RS03070	COG0561	phosphatase activity
STP1_RS03085	COG3711	transcriptional antiterminator
STP1_RS03110	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
STP1_RS03170	COG0489	protein tyrosine kinase activity
STP1_RS03175	COG2814	Major facilitator Superfamily
STP1_RS03190	COG1272	protein, Hemolysin III
STP1_RS03195	COG4284	Utp--glucose-1-phosphate uridylyltransferase
STP1_RS03200	COG1988	membrane-bound metal-dependent
STP1_RS03210	COG2329	Antibiotic biosynthesis monooxygenase
STP1_RS03215	COG3314	Sporulation integral membrane protein YlbJ
STP1_RS03220	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
STP1_RS03225	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
STP1_RS03230	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
STP1_RS03235	COG3457	Alanine racemase
STP1_RS03240	COG4264	IucA IucC family
STP1_RS03245	COG2814	Major facilitator Superfamily
STP1_RS03255	COG1302	Protein conserved in bacteria
STP1_RS03270	COG0604	alcohol dehydrogenase
STP1_RS03275	COG2130	NADP-dependent
STP1_RS03280	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
STP1_RS03305	COG1388	LysM domain
STP1_RS03305	COG5632	N-Acetylmuramoyl-L-alanine amidase
STP1_RS03470	COG0756	dUTP diphosphatase activity
STP1_RS03525	COG0305	Participates in initiation and elongation during chromosome replication
STP1_RS03610	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
STP1_RS03640	COG0698	ribose 5-phosphate isomerase
STP1_RS03665	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
STP1_RS03670	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
STP1_RS03675	COG0101	tRNA pseudouridine synthase activity
STP1_RS03685	COG1122	ATPase activity
STP1_RS03700	COG0202	RNA polymerase activity
STP1_RS03705	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
STP1_RS03710	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
STP1_RS03720	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
STP1_RS03725	COG0563	adenylate kinase activity
STP1_RS03730	COG0201	protein transport
STP1_RS03740	COG1841	ribosomal large subunit assembly
STP1_RS03745	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
STP1_RS03750	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
STP1_RS03755	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
STP1_RS03760	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
STP1_RS03765	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
STP1_RS03775	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
STP1_RS03780	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
STP1_RS03785	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
STP1_RS03795	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
STP1_RS03800	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
STP1_RS03805	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
STP1_RS03810	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
STP1_RS03815	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
STP1_RS03820	COG0089	rRNA binding
STP1_RS03825	COG0088	Forms part of the polypeptide exit tunnel
STP1_RS03830	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
STP1_RS03845	COG2252	PERMEase
STP1_RS03860	COG4975	Glucose uptake
STP1_RS03880	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
STP1_RS03885	COG2348	transferase activity, transferring amino-acyl groups
STP1_RS03905	COG2814	Major facilitator Superfamily
STP1_RS03915	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
STP1_RS03920	COG0746	molybdenum cofactor guanylyltransferase activity
STP1_RS03935	COG1763	Mo-molybdopterin cofactor biosynthetic process
STP1_RS03945	COG0315	cyclic pyranopterin monophosphate synthase activity
STP1_RS03950	COG0521	Mo-molybdopterin cofactor biosynthetic process
STP1_RS03955	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
STP1_RS03965	COG4149	molybdate abc transporter
STP1_RS03970	COG0725	ABC transporter, periplasmic molybdate-binding protein
STP1_RS03975	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
STP1_RS03985	COG1268	BioY protein
STP1_RS04000	COG1960	acyl-CoA dehydrogenase activity
STP1_RS04005	COG1126	abc transporter atp-binding protein
STP1_RS04010	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
STP1_RS04015	COG0765	amino acid transport
STP1_RS04020	COG0765	amino acid transport
STP1_RS04025	COG4413	Urea transporter
STP1_RS04030	COG0831	urea catabolic process
STP1_RS04040	COG0804	urea catabolic process
STP1_RS04045	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
STP1_RS04060	COG0829	nickel cation binding
STP1_RS04075	COG1846	Transcriptional regulator
STP1_RS04085	COG3942	CHAP domain
STP1_RS04090	COG1757	Na H antiporter
STP1_RS04105	COG3942	CHAP domain
STP1_RS04110	COG2076	Multidrug Resistance protein
STP1_RS04115	COG2076	Multidrug Resistance protein
STP1_RS04120	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
STP1_RS04150	COG1316	TRANSCRIPTIONal
STP1_RS04160	COG1349	DNA-binding transcription factor activity
STP1_RS04165	COG1266	CAAX protease self-immunity
STP1_RS04180	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
STP1_RS04185	COG1263	PTS System
STP1_RS04185	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
STP1_RS04195	COG1113	amino acid transport
STP1_RS04215	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
STP1_RS04220	COG0385	Bile acid
STP1_RS04230	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
STP1_RS04230	COG1263	PTS System
STP1_RS04235	COG1737	Transcriptional regulator
STP1_RS04255	COG1028	Short-chain dehydrogenase reductase Sdr
STP1_RS04260	COG1473	amidohydrolase
STP1_RS04265	COG0659	secondary active sulfate transmembrane transporter activity
STP1_RS04280	COG0583	DNA-binding transcription factor activity
STP1_RS04285	COG0010	Belongs to the arginase family
STP1_RS04290	COG1266	CAAX protease self-immunity
STP1_RS04300	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
STP1_RS04305	COG2258	MOSC domain
STP1_RS04310	COG2017	converts alpha-aldose to the beta-anomer
STP1_RS04315	COG1742	UPF0060 membrane protein
STP1_RS04320	COG1668	transmembrane transport
STP1_RS04325	COG4152	abc transporter atp-binding protein
STP1_RS04330	COG1069	ribulokinase activity
STP1_RS04340	COG3620	sequence-specific DNA binding
STP1_RS04350	COG2094	Belongs to the DNA glycosylase MPG family
STP1_RS04365	COG1695	Transcriptional regulator
STP1_RS04370	COG0786	glutamate:sodium symporter activity
STP1_RS04375	COG1304	FMN binding
STP1_RS04380	COG0598	Magnesium transport protein CorA
STP1_RS04405	COG2814	Major facilitator Superfamily
STP1_RS04410	COG1566	PFAM secretion protein HlyD family protein
STP1_RS04420	COG2814	Major facilitator Superfamily
STP1_RS04455	COG3850	Histidine kinase
STP1_RS04455	COG5002	protein histidine kinase activity
STP1_RS04470	COG0579	oxidoreductase
STP1_RS04475	COG0438	transferase activity, transferring glycosyl groups
STP1_RS04480	COG1620	l-lactate permease
STP1_RS04485	COG0463	Glycosyl transferase, family 2
STP1_RS04485	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
STP1_RS04495	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
STP1_RS04495	COG0463	Glycosyl transferase, family 2
STP1_RS04505	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
STP1_RS04510	COG0805	protein transport
STP1_RS04515	COG0672	)-iron permease
STP1_RS04520	COG2837	iron assimilation
STP1_RS04525	COG2822	iron ion transport
STP1_RS04530	COG0604	alcohol dehydrogenase
STP1_RS04535	COG0456	acetyltransferase
STP1_RS04540	COG0492	ferredoxin-NADP+ reductase activity
STP1_RS04575	COG1028	Short-chain dehydrogenase reductase Sdr
STP1_RS04585	COG0583	DNA-binding transcription factor activity
STP1_RS04590	COG2610	gluconate transmembrane transporter activity
STP1_RS04595	COG1028	Short-chain dehydrogenase reductase Sdr
STP1_RS04605	COG1511	domain protein
STP1_RS04620	COG1263	PTS System
STP1_RS04620	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
STP1_RS04655	COG0778	Nitroreductase
STP1_RS04670	COG2223	nitrite transmembrane transporter activity
STP1_RS04680	COG4585	Histidine kinase
STP1_RS04690	COG2181	nitrate reductase activity
STP1_RS04700	COG1140	nitrate reductase beta subunit
STP1_RS04705	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
STP1_RS04715	COG2146	nitrite reductase [NAD(P)H] activity
STP1_RS04720	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
STP1_RS04730	COG0747	negative chemotaxis
STP1_RS04735	COG0454	-acetyltransferase
STP1_RS04750	COG0803	Belongs to the bacterial solute-binding protein 9 family
STP1_RS04765	COG2348	transferase activity, transferring amino-acyl groups
STP1_RS04770	COG1126	abc transporter atp-binding protein
STP1_RS04775	COG0765	amino acid transport
STP1_RS04780	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
STP1_RS04785	COG2814	Major facilitator Superfamily
STP1_RS04790	COG0588	phosphoglycerate mutase activity
STP1_RS04795	COG0741	lytic transglycosylase activity
STP1_RS04800	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
STP1_RS04815	COG1929	Belongs to the glycerate kinase type-1 family
STP1_RS04825	COG2814	Major facilitator Superfamily
STP1_RS04840	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
STP1_RS04845	COG1113	amino acid transport
STP1_RS04850	COG0025	NhaP-type Na H and K H
STP1_RS04855	COG0531	amino acid
STP1_RS04865	COG0706	membrane insertase activity
STP1_RS04875	COG3477	response to acidic pH
STP1_RS04885	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
STP1_RS04895	COG1380	Effector of murein hydrolase LrgA
STP1_RS04900	COG1346	cytolysis
STP1_RS04905	COG1174	glycine betaine transport
STP1_RS04930	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
STP1_RS04935	COG0531	amino acid
STP1_RS04940	COG2272	Belongs to the type-B carboxylesterase lipase family
STP1_RS04945	COG2814	Major facilitator Superfamily
STP1_RS04960	COG0745	RESPONSE REGULATOR receiver
STP1_RS04965	COG2205	protein histidine kinase activity
STP1_RS04970	COG0390	transport system, permease component
STP1_RS04975	COG4619	ABC transporter
STP1_RS04980	COG1266	CAAX protease self-immunity
STP1_RS04990	COG0069	glutamate synthase activity
STP1_RS05005	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
STP1_RS05010	COG4808	Protein conserved in bacteria
STP1_RS05015	COG1363	Peptidase, m42
STP1_RS05020	COG1028	Short-chain dehydrogenase reductase Sdr
STP1_RS05025	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
STP1_RS05035	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
STP1_RS05040	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
STP1_RS05070	COG0508	dehydrogenase complex catalyzes the overall conversion of
STP1_RS05075	COG0022	dehydrogenase e1 component
STP1_RS05080	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
STP1_RS05085	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
STP1_RS05095	COG0494	nUDIX hydrolase
STP1_RS05100	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
STP1_RS05105	COG1215	transferase activity, transferring glycosyl groups
STP1_RS05120	COG1210	Utp--glucose-1-phosphate uridylyltransferase
STP1_RS05130	COG1070	Carbohydrate kinase
STP1_RS05135	COG1802	Transcriptional regulator
STP1_RS05150	COG2357	RelA SpoT domain protein
STP1_RS05155	COG4876	unkown
STP1_RS05165	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
STP1_RS05175	COG0352	thiamine-phosphate diphosphorylase activity
STP1_RS05180	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
STP1_RS05190	COG2022	thiamine diphosphate biosynthetic process
STP1_RS05195	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
STP1_RS05200	COG0586	Pfam SNARE associated Golgi protein
STP1_RS05205	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
STP1_RS05215	COG3949	Membrane
STP1_RS05220	COG1012	belongs to the aldehyde dehydrogenase family
STP1_RS05225	COG0583	DNA-binding transcription factor activity
STP1_RS05240	COG2514	catechol 2,3-dioxygenase activity
STP1_RS05265	COG1012	belongs to the aldehyde dehydrogenase family
STP1_RS05270	COG0778	Nitroreductase
STP1_RS05275	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
STP1_RS05285	COG3764	Sortase (surface protein transpeptidase)
STP1_RS05295	COG1760	l-serine dehydratase
STP1_RS05300	COG1760	l-serine dehydratase
STP1_RS05310	COG1070	Carbohydrate kinase
STP1_RS05325	COG2843	Capsule synthesis protein
STP1_RS05335	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
STP1_RS05345	COG0657	acetylesterase activity
STP1_RS05350	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
STP1_RS05355	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
STP1_RS05380	COG0028	Belongs to the TPP enzyme family
STP1_RS05385	COG1346	cytolysis
STP1_RS05390	COG1380	Effector of murein hydrolase LrgA
STP1_RS05395	COG0583	DNA-binding transcription factor activity
STP1_RS05405	COG1388	LysM domain
STP1_RS05405	COG3942	CHAP domain
STP1_RS05415	COG3425	synthase
STP1_RS05420	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
STP1_RS05430	COG0598	Magnesium transport protein CorA
STP1_RS05460	COG1012	belongs to the aldehyde dehydrogenase family
STP1_RS05470	COG1028	Short-chain dehydrogenase reductase Sdr
STP1_RS05485	COG2608	mercury ion transmembrane transporter activity
STP1_RS05495	COG0436	Aminotransferase
STP1_RS05510	COG0741	lytic transglycosylase activity
STP1_RS05565	COG4221	oxidoreductase activity
STP1_RS05575	COG0596	Alpha beta hydrolase
STP1_RS05585	COG3001	Fructosamine kinase
STP1_RS05590	COG0167	dihydroorotate dehydrogenase activity
STP1_RS05600	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
STP1_RS05630	COG4640	response to antibiotic
STP1_RS05645	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
STP1_RS05650	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
STP1_RS05660	COG3527	Alpha-acetolactate decarboxylase
STP1_RS05665	COG0028	Belongs to the TPP enzyme family
STP1_RS05670	COG0039	L-malate dehydrogenase activity
STP1_RS05675	COG0583	DNA-binding transcription factor activity
STP1_RS05685	COG0531	amino acid
STP1_RS05705	COG0446	pyridine nucleotide-disulphide oxidoreductase
STP1_RS05715	COG0563	adenylate kinase activity
STP1_RS05720	COG3588	fructose-bisphosphate aldolase
STP1_RS05725	COG1695	Transcriptional regulator
STP1_RS05735	COG2723	6-phospho-beta-galactosidase activity
STP1_RS05740	COG2190	(PTS) system
STP1_RS05740	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
STP1_RS05740	COG1263	PTS System
STP1_RS05750	COG0579	oxidoreductase
STP1_RS05755	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
STP1_RS05760	COG0574	Belongs to the PEP-utilizing enzyme family
STP1_RS05760	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
STP1_RS05765	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
STP1_RS05785	COG1473	amidohydrolase
STP1_RS05790	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
STP1_RS05795	COG1012	belongs to the aldehyde dehydrogenase family
STP1_RS05800	COG1510	regulation of RNA biosynthetic process
STP1_RS05810	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
STP1_RS05820	COG0602	queuosine metabolic process
STP1_RS05825	COG1328	CTP reductase activity
STP1_RS05830	COG3942	CHAP domain
STP1_RS05840	COG0529	Catalyzes the synthesis of activated sulfate
STP1_RS05845	COG2046	Belongs to the sulfate adenylyltransferase family
STP1_RS05850	COG0730	response to heat
STP1_RS05865	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
STP1_RS05870	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
STP1_RS05875	COG0175	sulfate reduction
STP1_RS05905	COG1136	(ABC) transporter
STP1_RS05910	COG2205	protein histidine kinase activity
STP1_RS05915	COG0745	RESPONSE REGULATOR receiver
STP1_RS05920	COG1785	Belongs to the alkaline phosphatase family
STP1_RS05925	COG4195	phage-related replication protein
STP1_RS05935	COG3961	Belongs to the TPP enzyme family
STP1_RS05955	COG3227	Zinc metalloprotease (Elastase)
STP1_RS05960	COG0739	heme binding
STP1_RS05970	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
STP1_RS05990	COG1705	Flagellar rod assembly protein muramidase FlgJ
STP1_RS05990	COG3942	CHAP domain
STP1_RS06000	COG1764	response to oxidative stress
STP1_RS06005	COG2409	Drug exporters of the RND superfamily
STP1_RS06010	COG2113	Glycine betaine
STP1_RS06030	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
STP1_RS06035	COG0477	Major facilitator Superfamily
STP1_RS06100	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
STP1_RS06105	COG0737	Belongs to the 5'-nucleotidase family
STP1_RS06110	COG2814	Major facilitator Superfamily
STP1_RS06125	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
STP1_RS06160	COG1288	antiporter activity
STP1_RS06185	COG1054	Belongs to the UPF0176 family
STP1_RS06190	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
STP1_RS06205	COG1695	Transcriptional regulator
STP1_RS06215	COG0471	metal ion transport
STP1_RS06220	COG2962	Rard protein
STP1_RS06225	COG3478	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
STP1_RS06230	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
STP1_RS06235	COG4221	oxidoreductase activity
STP1_RS06250	COG1136	(ABC) transporter
STP1_RS06260	COG2205	protein histidine kinase activity
STP1_RS06270	COG1131	(ABC) transporter
STP1_RS06275	COG0745	RESPONSE REGULATOR receiver
STP1_RS06360	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
STP1_RS06375	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
STP1_RS06375	COG0463	Glycosyl transferase, family 2
STP1_RS06380	COG1210	Utp--glucose-1-phosphate uridylyltransferase
STP1_RS06385	COG1288	antiporter activity
STP1_RS06395	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
STP1_RS06400	COG1882	Formate acetyltransferase
STP1_RS06405	COG1876	peptidase activity
STP1_RS06410	COG2910	NAD(P)H-binding
STP1_RS06415	COG1959	2 iron, 2 sulfur cluster binding
STP1_RS06425	COG2259	Doxx family
STP1_RS06440	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
STP1_RS06445	COG0656	L-ascorbic acid biosynthetic process
STP1_RS06450	COG0789	Transcriptional regulator
STP1_RS06455	COG1124	(ABC) transporter
STP1_RS06465	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
STP1_RS06470	COG0601	transmembrane transport
STP1_RS06475	COG0747	negative chemotaxis
STP1_RS06495	COG0201	protein transport
STP1_RS06505	COG1073	alpha beta
STP1_RS06515	COG0653	protein targeting
STP1_RS06520	COG0438	transferase activity, transferring glycosyl groups
STP1_RS06545	COG0659	secondary active sulfate transmembrane transporter activity
STP1_RS06550	COG1438	arginine binding
STP1_RS06555	COG2235	arginine
STP1_RS06575	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
STP1_RS06580	COG1250	3-hydroxyacyl-CoA dehydrogenase
STP1_RS06600	COG0706	membrane insertase activity
STP1_RS06605	COG1482	cell wall glycoprotein biosynthetic process
STP1_RS06610	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
STP1_RS06610	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
STP1_RS06610	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
STP1_RS06615	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
STP1_RS06615	COG3711	transcriptional antiterminator
STP1_RS06640	COG1518	maintenance of DNA repeat elements
STP1_RS06650	COG0346	lactoylglutathione lyase activity
STP1_RS06660	COG1124	(ABC) transporter
STP1_RS06665	COG0444	Belongs to the ABC transporter superfamily
STP1_RS06675	COG0601	transmembrane transport
STP1_RS06705	COG1131	(ABC) transporter
STP1_RS06725	COG2814	Major facilitator Superfamily
STP1_RS06740	COG0604	alcohol dehydrogenase
STP1_RS06750	COG1869	D-ribose catabolic process
STP1_RS06760	COG1609	Transcriptional regulator
STP1_RS06805	COG2814	Major facilitator Superfamily
STP1_RS06810	COG1114	Component of the transport system for branched-chain amino acids
STP1_RS06820	COG0110	maltose O-acetyltransferase activity
STP1_RS06825	COG0583	DNA-binding transcription factor activity
STP1_RS06835	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
STP1_RS06840	COG0583	DNA-binding transcription factor activity
STP1_RS06850	COG0789	Transcriptional regulator
STP1_RS06860	COG0656	L-ascorbic acid biosynthetic process
STP1_RS06870	COG2808	Putative FMN-binding domain
STP1_RS06895	COG2226	methyltransferase
STP1_RS06900	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
STP1_RS06905	COG2814	Major facilitator Superfamily
STP1_RS06910	COG0300	oxidoreductase activity
STP1_RS06915	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
STP1_RS06920	COG2851	Citrate transporter
STP1_RS06970	COG3223	Belongs to the PsiE family
STP1_RS06995	COG0464	growth
STP1_RS07005	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
STP1_RS07015	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
STP1_RS07040	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
STP1_RS07050	COG4863	YycH protein
STP1_RS07055	COG5002	protein histidine kinase activity
STP1_RS07060	COG0745	RESPONSE REGULATOR receiver
STP1_RS07080	COG0305	Participates in initiation and elongation during chromosome replication
STP1_RS07085	COG0359	binds to the 23S rRNA
STP1_RS07090	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
STP1_RS07100	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
STP1_RS07110	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
STP1_RS07125	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
STP1_RS07130	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
STP1_RS07135	COG0187	DNA topoisomerase II activity
STP1_RS07140	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
STP1_RS07145	COG2501	S4 domain
STP1_RS07150	COG0592	DNA-directed DNA polymerase activity
STP1_RS07155	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
STP1_RS07165	COG0594	ribonuclease P activity
STP1_RS07170	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
STP1_RS07175	COG0445	tRNA wobble uridine modification
STP1_RS07180	COG0357	Ribosomal RNA small subunit methyltransferase G
STP1_RS07185	COG1475	DNA binding
STP1_RS07225	COG1136	(ABC) transporter
STP1_RS07230	COG0577	efflux transmembrane transporter activity
STP1_RS07250	COG1073	alpha beta
STP1_RS07265	COG1063	alcohol dehydrogenase
STP1_RS07275	COG2348	transferase activity, transferring amino-acyl groups
STP1_RS07290	COG1682	transport, permease protein
STP1_RS07345	COG0577	efflux transmembrane transporter activity
STP1_RS07350	COG1136	(ABC) transporter
STP1_RS07370	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
STP1_RS07385	COG1131	(ABC) transporter
STP1_RS07395	COG1476	TRANSCRIPTIONal
STP1_RS07425	COG0183	Belongs to the thiolase family
STP1_RS07455	COG2814	Major facilitator Superfamily
STP1_RS07460	COG0640	Transcriptional regulator
STP1_RS07465	COG3942	CHAP domain
STP1_RS07480	COG1309	transcriptional regulator
STP1_RS07505	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
STP1_RS07510	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
STP1_RS07510	COG0646	methionine synthase
STP1_RS07515	COG0626	cystathionine gamma-synthase activity
STP1_RS07520	COG0626	cystathionine gamma-synthase activity
STP1_RS07525	COG1475	DNA binding
STP1_RS07530	COG0668	transmembrane transport
STP1_RS07535	COG4481	Protein conserved in bacteria
STP1_RS07540	COG0012	GTP binding
STP1_RS07555	COG0360	Binds together with S18 to 16S ribosomal RNA
STP1_RS07565	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
STP1_RS07575	COG0582	viral genome integration into host DNA
STP1_RS07645	COG3728	DNA packaging
STP1_RS07645	COG5484	DNA packaging
STP1_RS07665	COG1280	lysine exporter protein (LysE YggA)
STP1_RS07690	COG3634	alkyl hydroperoxide reductase activity
STP1_RS07695	COG0450	alkyl hydroperoxide reductase
STP1_RS07700	COG0778	Nitroreductase
STP1_RS07705	COG1823	symporter activity
STP1_RS07710	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
STP1_RS07715	COG5183	chlorophyll binding
STP1_RS07730	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
STP1_RS07735	COG2233	PERMEase
STP1_RS07740	COG0517	IMP dehydrogenase activity
STP1_RS07740	COG0516	GMP reductase activity
STP1_RS07745	COG0518	GMP synthase (glutamine-hydrolyzing) activity
STP1_RS07745	COG0519	Catalyzes the synthesis of GMP from XMP
STP1_RS07755	COG0523	cobalamin synthesis protein
STP1_RS07770	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
STP1_RS07775	COG3002	Belongs to the UPF0753 family
STP1_RS07780	COG5609	conserved protein (DUF2294)
STP1_RS07795	COG0671	phosphoesterase, PA-phosphatase related
STP1_RS07800	COG1647	Serine aminopeptidase, S33
STP1_RS07810	COG0733	neurotransmitter:sodium symporter activity
STP1_RS07815	COG1279	arginine transmembrane transporter activity
STP1_RS07830	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
STP1_RS07835	COG0626	cystathionine gamma-synthase activity
STP1_RS07840	COG1846	Transcriptional regulator
STP1_RS07865	COG3759	membrane
STP1_RS07870	COG1278	Cold shock
STP1_RS07880	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
STP1_RS07885	COG0438	transferase activity, transferring glycosyl groups
STP1_RS07895	COG0494	nUDIX hydrolase
STP1_RS07900	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
STP1_RS07925	COG0493	'glutamate synthase
STP1_RS07935	COG1263	PTS System
STP1_RS07935	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
STP1_RS07940	COG0366	Alpha amylase catalytic
STP1_RS07945	COG2188	Transcriptional regulator
STP1_RS07955	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
STP1_RS07965	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
STP1_RS07995	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
STP1_RS08000	COG1982	Orn Lys Arg decarboxylase major
STP1_RS08010	COG3870	Protein conserved in bacteria
STP1_RS08015	COG0470	DNA polymerase III
STP1_RS08020	COG1774	PSP1 C-terminal conserved region
STP1_RS08025	COG4467	Involved in initiation control of chromosome replication
STP1_RS08030	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
STP1_RS08035	COG2827	Endonuclease containing a URI domain
STP1_RS08040	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
STP1_RS08045	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
STP1_RS08045	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
STP1_RS08050	COG0084	hydrolase, TatD family'
STP1_RS08055	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
STP1_RS08060	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
STP1_RS08065	COG4466	Protein conserved in bacteria
STP1_RS08070	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
STP1_RS08075	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
STP1_RS08080	COG0251	oxidation-reduction process
STP1_RS08085	COG2088	sporulation resulting in formation of a cellular spore
STP1_RS08090	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
STP1_RS08095	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
STP1_RS08100	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
STP1_RS08105	COG0193	aminoacyl-tRNA hydrolase activity
STP1_RS08110	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
STP1_RS08115	COG2244	polysaccharide biosynthetic process
STP1_RS08120	COG3956	TIGRFAM MazG family protein
STP1_RS08125	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
STP1_RS08135	COG1098	S1 RNA binding domain
STP1_RS08150	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
STP1_RS08170	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
STP1_RS08175	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
STP1_RS08180	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
STP1_RS08245	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
STP1_RS08250	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
STP1_RS08255	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
STP1_RS08260	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
STP1_RS08270	COG3880	PFAM UvrB UvrC protein
STP1_RS08275	COG3869	Catalyzes the specific phosphorylation of arginine residues in
STP1_RS08280	COG0542	response to heat
STP1_RS08285	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
STP1_RS08290	COG4956	integral membrane protein (PIN domain superfamily)
STP1_RS08295	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
STP1_RS08305	COG0215	cysteine-tRNA ligase activity
STP1_RS08310	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
STP1_RS08320	COG3688	RNA-binding protein containing a PIN domain
STP1_RS08335	COG0250	Participates in transcription elongation, termination and antitermination
STP1_RS08340	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
STP1_RS08345	COG0081	regulation of translation
STP1_RS08350	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
STP1_RS08355	COG0222	ribosome binding
STP1_RS08360	COG2813	Specifically methylates the guanine in position
STP1_RS08365	COG0085	RNA polymerase activity
STP1_RS08370	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
STP1_RS08380	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
STP1_RS08385	COG0049	tRNA binding
STP1_RS08390	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
STP1_RS08395	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
STP1_RS08400	COG1473	amidohydrolase
STP1_RS08425	COG1349	DNA-binding transcription factor activity
STP1_RS08430	COG2814	Major facilitator Superfamily
STP1_RS08435	COG1063	alcohol dehydrogenase
STP1_RS08450	COG0737	Belongs to the 5'-nucleotidase family
STP1_RS08460	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
STP1_RS08465	COG0546	phosphoglycolate phosphatase activity
STP1_RS08470	COG1428	Deoxynucleoside kinase
STP1_RS08475	COG1428	Deoxynucleoside kinase
STP1_RS08485	COG0561	phosphatase activity
STP1_RS08490	COG0431	NADPH-dependent FMN reductase
STP1_RS08505	COG0438	transferase activity, transferring glycosyl groups
STP1_RS08510	COG2271	Major facilitator Superfamily
STP1_RS08515	COG1469	GTP cyclohydrolase I activity
STP1_RS08520	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
STP1_RS08530	COG0363	glucosamine-6-phosphate deaminase activity
STP1_RS08535	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
STP1_RS08550	COG0477	Major facilitator Superfamily
STP1_RS08575	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
STP1_RS08590	COG2363	Small membrane protein
STP1_RS08610	COG3253	May function as heme-dependent peroxidase
STP1_RS08615	COG0280	phosphate acetyltransferase
STP1_RS08620	COG0095	Lipoate-protein ligase
STP1_RS08625	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
STP1_RS08640	COG4844	belongs to the
STP1_RS08645	COG0667	Aldo Keto reductase
STP1_RS08650	COG0655	NAD(P)H dehydrogenase (quinone) activity
STP1_RS08655	COG0519	Catalyzes the synthesis of GMP from XMP
STP1_RS08660	COG1078	dGTPase activity
STP1_RS08670	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
STP1_RS08675	COG1691	(AIR) carboxylase
STP1_RS08680	COG1606	tRNA processing
STP1_RS08685	COG3875	lactate racemase activity
STP1_RS08700	COG0018	arginyl-trna synthetase
STP1_RS08705	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
STP1_RS08720	COG0534	Mate efflux family protein
STP1_RS08725	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
STP1_RS08730	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
STP1_RS08735	COG0546	phosphoglycolate phosphatase activity
STP1_RS08755	COG2267	carboxylic ester hydrolase activity
STP1_RS08790	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
STP1_RS08790	COG2111	Na H antiporter
STP1_RS08795	COG2111	Na H antiporter
STP1_RS08800	COG1006	Multisubunit Na H antiporter MnhC subunit
STP1_RS08805	COG0651	ATP synthesis coupled electron transport
STP1_RS08810	COG1863	multisubunit Na H antiporter MnhE subunit
STP1_RS08820	COG1320	monovalent cation:proton antiporter activity
STP1_RS08830	COG0803	Belongs to the bacterial solute-binding protein 9 family
STP1_RS08835	COG1108	ABC-type Mn2 Zn2 transport systems permease components
STP1_RS08840	COG1121	(ABC) transporter
STP1_RS08855	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
STP1_RS08860	COG1134	teichoic acid transport
STP1_RS08865	COG1682	transport, permease protein
STP1_RS08870	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
STP1_RS08880	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
STP1_RS08885	COG1686	Belongs to the peptidase S11 family
STP1_RS08890	COG1132	(ABC) transporter
STP1_RS08895	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
STP1_RS08900	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
STP1_RS08905	COG1120	ATPase activity
STP1_RS08910	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
STP1_RS08915	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
STP1_RS08920	COG2376	Dihydroxyacetone kinase
STP1_RS08930	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
STP1_RS08940	COG3949	Membrane
STP1_RS08945	COG0657	acetylesterase activity
STP1_RS08955	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
STP1_RS08965	COG2205	protein histidine kinase activity
STP1_RS08970	COG1136	(ABC) transporter
STP1_RS08975	COG0577	efflux transmembrane transporter activity
STP1_RS08985	COG1392	Phosphate transport regulator
STP1_RS08990	COG0306	phosphate transporter
STP1_RS09000	COG3942	CHAP domain
STP1_RS09000	COG1388	LysM domain
STP1_RS09010	COG2169	Transcriptional regulator
STP1_RS09020	COG0217	transcriptional regulatory protein
STP1_RS09035	COG0583	DNA-binding transcription factor activity
STP1_RS09040	COG2814	Major facilitator Superfamily
STP1_RS09045	COG2839	Protein conserved in bacteria
STP1_RS09070	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
STP1_RS09080	COG1959	2 iron, 2 sulfur cluster binding
STP1_RS09090	COG1611	Belongs to the LOG family
STP1_RS09095	COG1671	Belongs to the UPF0178 family
STP1_RS09105	COG1968	undecaprenyl-diphosphatase activity
STP1_RS09110	COG4988	ABC transporter
STP1_RS09115	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
STP1_RS09125	COG0523	cobalamin synthesis protein
STP1_RS09130	COG4989	oxidoreductase activity
STP1_RS09140	COG0039	L-malate dehydrogenase activity
STP1_RS09145	COG0471	metal ion transport
STP1_RS09150	COG0415	Belongs to the DNA photolyase family
STP1_RS09175	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
STP1_RS09180	COG1349	DNA-binding transcription factor activity
STP1_RS09185	COG1105	Belongs to the carbohydrate kinase PfkB family
STP1_RS09190	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
STP1_RS09190	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
STP1_RS09190	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
STP1_RS09195	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
STP1_RS09200	COG1253	flavin adenine dinucleotide binding
STP1_RS09205	COG0656	L-ascorbic acid biosynthetic process
STP1_RS09210	COG0463	Glycosyl transferase, family 2
STP1_RS09225	COG0720	synthase
STP1_RS09230	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
STP1_RS09235	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
STP1_RS09235	COG0512	Glutamine amidotransferase of anthranilate synthase
STP1_RS09265	COG1368	sulfuric ester hydrolase activity
STP1_RS09275	COG0488	(ABC) transporter
STP1_RS09280	COG0514	ATP-dependent DNA helicase (RecQ)
STP1_RS09290	COG1174	glycine betaine transport
STP1_RS09295	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
STP1_RS09305	COG1597	lipid kinase activity
STP1_RS09310	COG3104	oligopeptide transport
STP1_RS09325	COG1780	Probably involved in ribonucleotide reductase function
STP1_RS09330	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
STP1_RS09335	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
STP1_RS09345	COG4605	iron ion homeostasis
STP1_RS09350	COG4604	ABC transporter, ATP-binding protein
STP1_RS09365	COG0812	UDP-N-acetylmuramate dehydrogenase activity
STP1_RS09385	COG1929	Belongs to the glycerate kinase type-1 family
STP1_RS09390	COG2195	Cleaves the N-terminal amino acid of tripeptides
STP1_RS09410	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
STP1_RS09415	COG1739	Uncharacterized protein family UPF0029
STP1_RS09425	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
STP1_RS09430	COG1040	competence protein
STP1_RS09435	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
STP1_RS09440	COG0653	protein targeting
STP1_RS09445	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
STP1_RS09450	COG3942	CHAP domain
STP1_RS09450	COG1388	LysM domain
STP1_RS09465	COG0556	nucleotide-excision repair
STP1_RS09470	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
STP1_RS09480	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
STP1_RS09495	COG0492	ferredoxin-NADP+ reductase activity
STP1_RS09500	COG1660	Displays ATPase and GTPase activities
STP1_RS09505	COG0391	Required for morphogenesis under gluconeogenic growth conditions
STP1_RS09510	COG1481	regulation of sporulation
STP1_RS09520	COG0740	serine-type endopeptidase activity
STP1_RS09540	COG2390	Transcriptional regulator
STP1_RS09550	COG0126	phosphoglycerate kinase activity
STP1_RS09555	COG0149	triose-phosphate isomerase activity
STP1_RS09560	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
STP1_RS09565	COG0148	phosphopyruvate hydratase activity
STP1_RS09575	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
STP1_RS09580	COG1647	Serine aminopeptidase, S33
STP1_RS09585	COG0557	exoribonuclease II activity
STP1_RS09595	COG0582	viral genome integration into host DNA
STP1_RS09660	COG5484	DNA packaging
STP1_RS09660	COG3728	DNA packaging
STP1_RS09665	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
STP1_RS09675	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
STP1_RS09735	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
STP1_RS09745	COG1278	Cold shock
STP1_RS09770	COG4195	phage-related replication protein
STP1_RS09805	COG0406	alpha-ribazole phosphatase activity
STP1_RS09815	COG1764	response to oxidative stress
STP1_RS09820	COG0710	3-dehydroquinate dehydratase activity
STP1_RS09830	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
STP1_RS09835	COG1393	Belongs to the ArsC family
STP1_RS09840	COG0509	glycine decarboxylation via glycine cleavage system
STP1_RS09845	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
STP1_RS09855	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
STP1_RS09860	COG2011	ABC-type metal ion transport system permease component
STP1_RS09865	COG1464	Belongs to the NlpA lipoprotein family
STP1_RS09875	COG0396	ATPase activity
STP1_RS09880	COG0719	Fe-S assembly protein
STP1_RS09885	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
STP1_RS09890	COG0822	iron-sulfur transferase activity
STP1_RS09895	COG0719	Fe-S assembly protein
STP1_RS09985	COG1484	DNA-dependent DNA replication
STP1_RS10075	COG0740	serine-type endopeptidase activity
STP1_RS10115	COG0739	heme binding
STP1_RS10180	COG1253	flavin adenine dinucleotide binding
STP1_RS10185	COG2070	2-Nitropropane dioxygenase
STP1_RS10190	COG1801	Protein of unknown function DUF72
STP1_RS10195	COG0730	response to heat
STP1_RS10200	COG0737	Belongs to the 5'-nucleotidase family
STP1_RS10205	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
STP1_RS10210	COG4470	Protein conserved in bacteria
STP1_RS10220	COG2445	Protein of unknown function DUF86
STP1_RS10240	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
STP1_RS10245	COG1696	Membrane protein involved in D-alanine export
STP1_RS10255	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
STP1_RS10265	COG0583	DNA-binding transcription factor activity
STP1_RS10270	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
STP1_RS10275	COG4837	Protein of unknown function (DUF1462)
STP1_RS10280	COG1252	NADH dehydrogenase
STP1_RS10285	COG4844	belongs to the
STP1_RS10290	COG0316	Belongs to the HesB IscA family
STP1_RS10300	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
STP1_RS10305	COG2056	Na+-H+ antiporter family
STP1_RS10310	COG2050	protein possibly involved in aromatic compounds catabolism
STP1_RS10320	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
STP1_RS10330	COG2212	antiporter activity
STP1_RS10340	COG0651	ATP synthesis coupled electron transport
STP1_RS10345	COG1006	Multisubunit Na H antiporter MnhC subunit
STP1_RS10350	COG2111	Na H antiporter
STP1_RS10370	COG1098	S1 RNA binding domain
STP1_RS10375	COG1902	pentaerythritol trinitrate reductase activity
STP1_RS10395	COG0584	glycerophosphoryl diester phosphodiesterase
STP1_RS10400	COG0584	glycerophosphoryl diester phosphodiesterase
STP1_RS10405	COG0165	Argininosuccinate lyase
STP1_RS10410	COG0137	argininosuccinate synthase activity
STP1_RS10420	COG0398	Pfam SNARE associated Golgi protein
STP1_RS10440	COG1074	ATP-dependent DNA helicase activity
STP1_RS10465	COG0561	phosphatase activity
STP1_RS10480	COG0542	response to heat
STP1_RS10490	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
STP1_RS10500	COG0601	transmembrane transport
STP1_RS10505	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
STP1_RS10510	COG0444	Belongs to the ABC transporter superfamily
STP1_RS10515	COG4608	Belongs to the ABC transporter superfamily
STP1_RS10520	COG4166	transmembrane transport
STP1_RS10525	COG0180	Tryptophanyl-tRNA synthetase
STP1_RS10530	COG1393	Belongs to the ArsC family
STP1_RS10535	COG4862	establishment of competence for transformation
STP1_RS10545	COG1164	Oligoendopeptidase f
STP1_RS10550	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
STP1_RS10555	COG2346	COG2346, Truncated hemoglobins
STP1_RS10570	COG2357	RelA SpoT domain protein
STP1_RS10575	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
STP1_RS10580	COG0564	pseudouridine synthase activity
STP1_RS10585	COG2239	Acts as a magnesium transporter
STP1_RS10590	COG0569	domain protein
STP1_RS10590	COG0475	glutathione-regulated potassium exporter activity
STP1_RS10600	COG0628	permease
STP1_RS10605	COG1115	amino acid carrier protein
STP1_RS10610	COG2382	esterase
STP1_RS10615	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
STP1_RS10620	COG2814	Major facilitator Superfamily
STP1_RS10625	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
STP1_RS10630	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
STP1_RS10640	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
STP1_RS10645	COG0861	Integral membrane protein TerC family
STP1_RS10650	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
STP1_RS10655	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
STP1_RS10670	COG4873	Protein conserved in bacteria
STP1_RS10705	COG2314	TM2 domain
STP1_RS10715	COG1575	Belongs to the MenA family. Type 1 subfamily
STP1_RS10720	COG1169	isochorismate synthase
STP1_RS10725	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
STP1_RS10735	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
STP1_RS10740	COG0436	Aminotransferase
STP1_RS10745	COG3594	Acyltransferase
STP1_RS10770	COG1316	TRANSCRIPTIONal
STP1_RS10785	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
STP1_RS10800	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
STP1_RS10810	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
STP1_RS10810	COG1017	nitric oxide dioxygenase activity
STP1_RS10815	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
STP1_RS10820	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
STP1_RS10830	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
STP1_RS10835	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
STP1_RS10840	COG0047	phosphoribosylformylglycinamidine synthase activity
STP1_RS10855	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
STP1_RS10865	COG0138	bifunctional purine biosynthesis protein purh
STP1_RS10870	COG0151	Belongs to the GarS family
STP1_RS10875	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
STP1_RS10880	COG4172	Belongs to the ABC transporter superfamily
STP1_RS10900	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
STP1_RS10910	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
STP1_RS10915	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
STP1_RS10925	COG1271	oxidase subunit
STP1_RS10930	COG1294	oxidase, subunit
STP1_RS10935	COG0569	domain protein
STP1_RS10940	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
STP1_RS10945	COG5503	Protein of unknown function (DUF1447)
STP1_RS10950	COG0242	peptide deformylase activity
STP1_RS10970	COG0508	dehydrogenase complex catalyzes the overall conversion of
STP1_RS10980	COG4476	Belongs to the UPF0223 family
STP1_RS10995	COG1176	ABC-type spermidine putrescine transport system, permease component I
STP1_RS11000	COG1177	transmembrane transport
STP1_RS11025	COG4493	Belongs to the UPF0637 family
STP1_RS11030	COG0483	inositol monophosphate 1-phosphatase activity
STP1_RS11040	COG1217	gtp-binding protein TYPA
STP1_RS11045	COG4896	Protein conserved in bacteria
STP1_RS11050	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
STP1_RS11055	COG4838	Belongs to the UPF0358 family
STP1_RS11060	COG0772	Belongs to the SEDS family
STP1_RS11070	COG1612	heme a metabolic process
STP1_RS11075	COG0109	protoheme IX farnesyltransferase activity
STP1_RS11090	COG3679	Belongs to the UPF0342 family
STP1_RS11095	COG0584	glycerophosphoryl diester phosphodiesterase
STP1_RS11110	COG0742	ribosomal rna small subunit methyltransferase
STP1_RS11115	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
STP1_RS11130	COG0333	Belongs to the bacterial ribosomal protein bL32 family
STP1_RS11140	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
STP1_RS11145	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
STP1_RS11150	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
STP1_RS11150	COG0072	phenylalanine-tRNA ligase activity
STP1_RS11155	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
STP1_RS11160	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
STP1_RS11170	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
STP1_RS11170	COG1796	DNA polymerase
STP1_RS11175	COG1193	negative regulation of DNA recombination
STP1_RS11180	COG3118	belongs to the thioredoxin family
STP1_RS11185	COG0322	excinuclease ABC activity
STP1_RS11190	COG2009	succinate dehydrogenase
STP1_RS11195	COG1053	succinate dehydrogenase
STP1_RS11200	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
STP1_RS11210	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
STP1_RS11240	COG1011	Hydrolase
STP1_RS11250	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
STP1_RS11260	COG0275	rRNA processing
STP1_RS11265	COG4839	cell division protein FtsL
STP1_RS11270	COG0768	penicillin binding
STP1_RS11275	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
STP1_RS11285	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
STP1_RS11290	COG0849	cell division
STP1_RS11295	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
STP1_RS11300	COG1496	oxidoreductase activity
STP1_RS11305	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
STP1_RS11310	COG1799	cell septum assembly
STP1_RS11315	COG0762	integral membrane protein
STP1_RS11325	COG3599	regulation of cell shape
STP1_RS11330	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
STP1_RS11340	COG3942	CHAP domain
STP1_RS11340	COG1388	LysM domain
STP1_RS11350	COG0564	pseudouridine synthase activity
STP1_RS11360	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
STP1_RS11365	COG2233	PERMEase
STP1_RS11370	COG0540	Belongs to the ATCase OTCase family
STP1_RS11375	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
STP1_RS11380	COG0505	Belongs to the CarA family
STP1_RS11385	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
STP1_RS11390	COG0284	orotidine-5'-phosphate decarboxylase activity
STP1_RS11395	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
STP1_RS11415	COG0194	GDP metabolic process
STP1_RS11420	COG1758	RNA polymerase activity
STP1_RS11425	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
STP1_RS11430	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
STP1_RS11445	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
STP1_RS11450	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
STP1_RS11450	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
STP1_RS11455	COG0820	rRNA (adenine-C2-)-methyltransferase activity
STP1_RS11460	COG0631	protein serine/threonine phosphatase activity
STP1_RS11475	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
STP1_RS11485	COG0227	Belongs to the bacterial ribosomal protein bL28 family
STP1_RS11490	COG1302	Protein conserved in bacteria
STP1_RS11495	COG1461	Dihydroxyacetone kinase
STP1_RS11500	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
STP1_RS11505	COG1349	DNA-binding transcription factor activity
STP1_RS11510	COG0416	fatty acid biosynthetic process
STP1_RS11530	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
STP1_RS11535	COG0571	ribonuclease III activity
STP1_RS11540	COG1196	nuclear chromosome segregation
STP1_RS11545	COG0552	protein localization to endoplasmic reticulum
STP1_RS11550	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
STP1_RS11555	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
STP1_RS11560	COG0228	four-way junction DNA binding
STP1_RS11565	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
STP1_RS11570	COG0336	Belongs to the RNA methyltransferase TrmD family
STP1_RS11585	COG4485	Bacterial membrane protein, YfhO
STP1_RS11595	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
STP1_RS11600	COG0045	succinate-CoA ligase (ADP-forming) activity
STP1_RS11605	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
STP1_RS11610	COG0758	DNA mediated transformation
STP1_RS11615	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
STP1_RS11620	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
STP1_RS11625	COG4974	Belongs to the 'phage' integrase family
STP1_RS11630	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
STP1_RS11645	COG0052	Belongs to the universal ribosomal protein uS2 family
STP1_RS11650	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
STP1_RS11655	COG0528	UMP kinase activity
STP1_RS11660	COG0233	cytoplasmic translational termination
STP1_RS11665	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
STP1_RS11670	COG4589	Belongs to the CDS family
STP1_RS11680	COG0442	prolyl-tRNA aminoacylation
STP1_RS11685	COG2176	DNA-directed DNA polymerase activity
STP1_RS11690	COG0779	Required for maturation of 30S ribosomal subunits
STP1_RS11695	COG0195	Participates in both transcription termination and antitermination
STP1_RS11700	COG2740	Nucleic-acid-binding protein implicated in transcription termination
STP1_RS11705	COG1358	cellular component organization or biogenesis
STP1_RS11710	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
STP1_RS11715	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
STP1_RS11720	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
STP1_RS11725	COG0196	riboflavin kinase activity
STP1_RS11730	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
STP1_RS11735	COG1185	polyribonucleotide nucleotidyltransferase activity
STP1_RS11740	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
STP1_RS11750	COG2188	Transcriptional regulator
STP1_RS11755	COG0612	Peptidase, M16
STP1_RS11760	COG0612	Peptidase, M16
STP1_RS11765	COG1028	Short-chain dehydrogenase reductase Sdr
STP1_RS11785	COG1546	Belongs to the CinA family
STP1_RS11785	COG1058	Belongs to the CinA family
STP1_RS11790	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
STP1_RS11795	COG1418	mRNA catabolic process
STP1_RS11805	COG1692	metallophosphoesterase
STP1_RS11810	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
STP1_RS11810	COG0674	pyruvate-flavodoxin oxidoreductase activity
STP1_RS11815	COG1013	pyruvate-flavodoxin oxidoreductase activity
STP1_RS11820	COG4195	phage-related replication protein
STP1_RS11830	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
STP1_RS11835	COG4550	Control of competence regulator ComK, YlbF/YmcA
STP1_RS11855	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
STP1_RS11860	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
STP1_RS11865	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
STP1_RS11875	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
STP1_RS11885	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
STP1_RS11890	COG1923	regulation of RNA biosynthetic process
STP1_RS11895	COG0386	Belongs to the glutathione peroxidase family
STP1_RS11900	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
STP1_RS11905	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
STP1_RS11910	COG0789	Transcriptional regulator
STP1_RS11960	COG4585	Histidine kinase
STP1_RS11965	COG2197	response regulator
STP1_RS11975	COG1525	nuclease
STP1_RS11990	COG0527	aspartate kinase activity
STP1_RS11995	COG0460	homoserine dehydrogenase
STP1_RS12000	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
STP1_RS12005	COG0083	homoserine kinase activity
STP1_RS12020	COG0833	amino acid
STP1_RS12035	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
STP1_RS12060	COG4224	UPF0291 protein
STP1_RS12075	COG3763	UPF0154 protein
STP1_RS12080	COG4846	Membrane protein involved in cytochrome C biogenesis
STP1_RS12095	COG1970	mechanosensitive ion channel activity
STP1_RS12100	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
STP1_RS12105	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
STP1_RS12110	COG0824	Thioesterase
STP1_RS12125	COG0187	DNA topoisomerase II activity
STP1_RS12130	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
STP1_RS12135	COG1115	amino acid carrier protein
STP1_RS12140	COG3711	transcriptional antiterminator
STP1_RS12145	COG0628	permease
STP1_RS12150	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
STP1_RS12150	COG0392	lysyltransferase activity
STP1_RS12165	COG1942	4-Oxalocrotonate Tautomerase
STP1_RS12170	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
STP1_RS12175	COG0287	Prephenate dehydrogenase
STP1_RS12185	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
STP1_RS12190	COG0512	Glutamine amidotransferase of anthranilate synthase
STP1_RS12200	COG0134	indole-3-glycerol-phosphate synthase activity
STP1_RS12220	COG2348	transferase activity, transferring amino-acyl groups
STP1_RS12225	COG2348	transferase activity, transferring amino-acyl groups
STP1_RS12230	COG0561	phosphatase activity
STP1_RS12235	COG4607	ABC-type enterochelin transport system periplasmic component
STP1_RS12275	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
STP1_RS12280	COG0581	inorganic phosphate transmembrane transporter activity
STP1_RS12285	COG0573	inorganic phosphate transmembrane transporter activity
STP1_RS12290	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
STP1_RS12295	COG2996	Protein conserved in bacteria
STP1_RS12300	COG0488	(ABC) transporter
STP1_RS12305	COG0527	aspartate kinase activity
STP1_RS12310	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
STP1_RS12315	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
STP1_RS12320	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
STP1_RS12330	COG1473	amidohydrolase
STP1_RS12345	COG1278	Cold shock
STP1_RS12355	COG1254	Belongs to the acylphosphatase family
STP1_RS12365	COG3853	Toxic anion resistance protein (TelA)
STP1_RS12410	COG0025	NhaP-type Na H and K H
STP1_RS12435	COG5632	N-Acetylmuramoyl-L-alanine amidase
STP1_RS12435	COG1388	LysM domain