locus-tag	class	description
DNH82_RS00025	COG3942	CHAP domain
DNH82_RS00035	COG1757	Na H antiporter
DNH82_RS00045	COG3942	CHAP domain
DNH82_RS00050	COG2076	Multidrug Resistance protein
DNH82_RS00055	COG2076	Multidrug Resistance protein
DNH82_RS00060	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DNH82_RS00085	COG3383	formate dehydrogenase (NAD+) activity
DNH82_RS00090	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
DNH82_RS00105	COG1316	TRANSCRIPTIONal
DNH82_RS00130	COG1113	amino acid transport
DNH82_RS00155	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DNH82_RS00160	COG0346	lactoylglutathione lyase activity
DNH82_RS00170	COG0385	Bile acid
DNH82_RS00190	COG1473	amidohydrolase
DNH82_RS00195	COG0659	secondary active sulfate transmembrane transporter activity
DNH82_RS00200	COG1228	amidohydrolase
DNH82_RS00205	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
DNH82_RS00210	COG3314	Sporulation integral membrane protein YlbJ
DNH82_RS00215	COG0583	DNA-binding transcription factor activity
DNH82_RS00225	COG1131	(ABC) transporter
DNH82_RS00295	COG2801	Transposase and inactivated derivatives
DNH82_RS00320	COG1266	CAAX protease self-immunity
DNH82_RS00330	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
DNH82_RS00335	COG2258	MOSC domain
DNH82_RS00340	COG2017	converts alpha-aldose to the beta-anomer
DNH82_RS00345	COG1742	UPF0060 membrane protein
DNH82_RS00350	COG1668	transmembrane transport
DNH82_RS00355	COG4152	abc transporter atp-binding protein
DNH82_RS00360	COG3152	Membrane
DNH82_RS00365	COG2094	Belongs to the DNA glycosylase MPG family
DNH82_RS00370	COG1757	Na H antiporter
DNH82_RS00390	COG3250	beta-galactosidase activity
DNH82_RS00395	COG2207	Transcriptional regulator
DNH82_RS00400	COG0786	glutamate:sodium symporter activity
DNH82_RS00405	COG0523	cobalamin synthesis protein
DNH82_RS00410	COG1304	FMN binding
DNH82_RS00430	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DNH82_RS00440	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
DNH82_RS00475	COG0577	efflux transmembrane transporter activity
DNH82_RS00490	COG0579	oxidoreductase
DNH82_RS00495	COG0438	transferase activity, transferring glycosyl groups
DNH82_RS00500	COG1620	l-lactate permease
DNH82_RS00515	COG0604	alcohol dehydrogenase
DNH82_RS00520	COG2814	Major facilitator Superfamily
DNH82_RS00525	COG0492	ferredoxin-NADP+ reductase activity
DNH82_RS00545	COG1283	sodium-dependent phosphate transmembrane transporter activity
DNH82_RS00560	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DNH82_RS00560	COG1263	PTS System
DNH82_RS00570	COG2807	transmembrane transport
DNH82_RS00580	COG0697	spore germination
DNH82_RS00585	COG1363	Peptidase, m42
DNH82_RS00590	COG0039	L-malate dehydrogenase activity
DNH82_RS00600	COG4187	Peptidase family M20/M25/M40
DNH82_RS00605	COG3344	reverse transcriptase
DNH82_RS00610	COG2223	nitrite transmembrane transporter activity
DNH82_RS00615	COG2197	response regulator
DNH82_RS00620	COG4585	Histidine kinase
DNH82_RS00630	COG2181	nitrate reductase activity
DNH82_RS00640	COG1140	nitrate reductase beta subunit
DNH82_RS00645	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
DNH82_RS00665	COG0018	arginyl-trna synthetase
DNH82_RS00700	COG0737	Belongs to the 5'-nucleotidase family
DNH82_RS00705	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
DNH82_RS00705	COG1648	precorrin-2 dehydrogenase activity
DNH82_RS00710	COG2146	nitrite reductase [NAD(P)H] activity
DNH82_RS00715	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
DNH82_RS00720	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
DNH82_RS00720	COG1648	precorrin-2 dehydrogenase activity
DNH82_RS00730	COG0454	-acetyltransferase
DNH82_RS00735	COG2116	formate transmembrane transporter activity
DNH82_RS00740	COG0471	metal ion transport
DNH82_RS00790	COG1760	l-serine dehydratase
DNH82_RS00795	COG1760	l-serine dehydratase
DNH82_RS00805	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DNH82_RS00810	COG0601	transmembrane transport
DNH82_RS00815	COG4608	Belongs to the ABC transporter superfamily
DNH82_RS00820	COG0444	Belongs to the ABC transporter superfamily
DNH82_RS00825	COG4166	transmembrane transport
DNH82_RS00830	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DNH82_RS00835	COG0601	transmembrane transport
DNH82_RS00840	COG4608	Belongs to the ABC transporter superfamily
DNH82_RS00845	COG0444	Belongs to the ABC transporter superfamily
DNH82_RS00850	COG4166	transmembrane transport
DNH82_RS00855	COG0702	epimerase
DNH82_RS00860	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
DNH82_RS00880	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
DNH82_RS00890	COG1929	Belongs to the glycerate kinase type-1 family
DNH82_RS00895	COG3764	Sortase (surface protein transpeptidase)
DNH82_RS00900	COG2271	Major facilitator Superfamily
DNH82_RS00905	COG2814	Major facilitator Superfamily
DNH82_RS00910	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
DNH82_RS00915	COG1115	amino acid carrier protein
DNH82_RS00920	COG3871	stress protein (general stress protein 26)
DNH82_RS00925	COG0789	Transcriptional regulator
DNH82_RS00930	COG1132	(ABC) transporter
DNH82_RS00935	COG1132	(ABC) transporter
DNH82_RS00940	COG0247	lactate metabolic process
DNH82_RS00945	COG0277	FAD linked oxidase domain protein
DNH82_RS00965	COG0159	tryptophan synthase activity
DNH82_RS00970	COG0133	tryptophan synthase activity
DNH82_RS00980	COG0134	indole-3-glycerol-phosphate synthase activity
DNH82_RS00990	COG0512	Glutamine amidotransferase of anthranilate synthase
DNH82_RS00995	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
DNH82_RS01000	COG3961	Belongs to the TPP enzyme family
DNH82_RS01005	COG2855	membrane
DNH82_RS01010	COG3835	regulator
DNH82_RS01025	COG1028	Short-chain dehydrogenase reductase Sdr
DNH82_RS01065	COG2357	RelA SpoT domain protein
DNH82_RS01080	COG1846	Transcriptional regulator
DNH82_RS01095	COG1346	cytolysis
DNH82_RS01105	COG0583	DNA-binding transcription factor activity
DNH82_RS01130	COG1141	Ferredoxin
DNH82_RS01140	COG0523	cobalamin synthesis protein
DNH82_RS01145	COG0717	Belongs to the dCTP deaminase family
DNH82_RS01150	COG0804	urea catabolic process
DNH82_RS01155	COG0832	Belongs to the urease beta subunit family
DNH82_RS01165	COG4413	Urea transporter
DNH82_RS01175	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
DNH82_RS01185	COG0577	efflux transmembrane transporter activity
DNH82_RS01190	COG1136	(ABC) transporter
DNH82_RS01215	COG3001	Fructosamine kinase
DNH82_RS01220	COG0778	Nitroreductase
DNH82_RS01225	COG3181	Tripartite tricarboxylate transporter family receptor
DNH82_RS01240	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
DNH82_RS01245	COG2801	Transposase and inactivated derivatives
DNH82_RS01260	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
DNH82_RS01265	COG1063	alcohol dehydrogenase
DNH82_RS01270	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
DNH82_RS01280	COG0463	Glycosyl transferase, family 2
DNH82_RS01280	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
DNH82_RS01305	COG0747	negative chemotaxis
DNH82_RS01310	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
DNH82_RS01315	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
DNH82_RS01325	COG3942	CHAP domain
DNH82_RS01325	COG1705	Flagellar rod assembly protein muramidase FlgJ
DNH82_RS01335	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DNH82_RS01335	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DNH82_RS01335	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DNH82_RS01340	COG0789	Transcriptional regulator
DNH82_RS01345	COG0596	Alpha beta hydrolase
DNH82_RS01360	COG1012	belongs to the aldehyde dehydrogenase family
DNH82_RS01365	COG2824	Alkylphosphonate utilization operon protein PhnA
DNH82_RS01370	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
DNH82_RS01375	COG1461	Dihydroxyacetone kinase
DNH82_RS01415	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
DNH82_RS01420	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
DNH82_RS01425	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
DNH82_RS01430	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
DNH82_RS01445	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
DNH82_RS01450	COG0107	imidazoleglycerol-phosphate synthase activity
DNH82_RS01465	COG0156	8-amino-7-oxononanoate synthase activity
DNH82_RS01475	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
DNH82_RS01480	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
DNH82_RS01485	COG1012	belongs to the aldehyde dehydrogenase family
DNH82_RS01490	COG1510	regulation of RNA biosynthetic process
DNH82_RS01515	COG1785	Belongs to the alkaline phosphatase family
DNH82_RS01530	COG1396	sequence-specific DNA binding
DNH82_RS01535	COG2807	transmembrane transport
DNH82_RS01540	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
DNH82_RS01545	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
DNH82_RS01585	COG1957	nucleoside hydrolase
DNH82_RS01590	COG3250	beta-galactosidase activity
DNH82_RS01595	COG2211	Major facilitator Superfamily
DNH82_RS01600	COG0477	Major facilitator Superfamily
DNH82_RS01605	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
DNH82_RS01610	COG1210	Utp--glucose-1-phosphate uridylyltransferase
DNH82_RS01620	COG2972	Histidine kinase
DNH82_RS01625	COG4753	response regulator
DNH82_RS01625	COG2207	Transcriptional regulator
DNH82_RS01695	COG3443	Belongs to the bacterial solute-binding protein 9 family
DNH82_RS01695	COG0803	Belongs to the bacterial solute-binding protein 9 family
DNH82_RS01705	COG1328	CTP reductase activity
DNH82_RS01715	COG3037	sugar-specific permease SgaT UlaA
DNH82_RS01725	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DNH82_RS01730	COG3711	transcriptional antiterminator
DNH82_RS01755	COG1869	D-ribose catabolic process
DNH82_RS01760	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DNH82_RS01765	COG1609	Transcriptional regulator
DNH82_RS01795	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DNH82_RS01805	COG2814	Major facilitator Superfamily
DNH82_RS01815	COG0318	PFAM AMP-dependent synthetase and ligase
DNH82_RS01830	COG0183	Belongs to the thiolase family
DNH82_RS01835	COG0438	transferase activity, transferring glycosyl groups
DNH82_RS01855	COG1073	alpha beta
DNH82_RS01875	COG0579	oxidoreductase
DNH82_RS01900	COG1755	Isoprenylcysteine carboxyl methyltransferase
DNH82_RS01915	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DNH82_RS01925	COG1136	(ABC) transporter
DNH82_RS01950	COG0436	Aminotransferase
DNH82_RS01960	COG0783	Belongs to the Dps family
DNH82_RS01970	COG0753	catalase activity
DNH82_RS01975	COG2318	DinB family
DNH82_RS01990	COG0076	glutamate decarboxylase activity
DNH82_RS02005	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
DNH82_RS02050	COG0156	8-amino-7-oxononanoate synthase activity
DNH82_RS02055	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
DNH82_RS02060	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
DNH82_RS02065	COG1620	l-lactate permease
DNH82_RS02080	COG1063	alcohol dehydrogenase
DNH82_RS02100	COG3314	Sporulation integral membrane protein YlbJ
DNH82_RS02120	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
DNH82_RS02130	COG3716	PTS system mannose fructose sorbose family IID component
DNH82_RS02135	COG3715	PTS system
DNH82_RS02140	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DNH82_RS02140	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
DNH82_RS02155	COG1105	Belongs to the carbohydrate kinase PfkB family
DNH82_RS02160	COG2222	sugar isomerase
DNH82_RS02165	COG2188	Transcriptional regulator
DNH82_RS02170	COG0366	Alpha amylase catalytic
DNH82_RS02180	COG1131	(ABC) transporter
DNH82_RS02210	COG0346	lactoylglutathione lyase activity
DNH82_RS02220	COG0490	domain, Protein
DNH82_RS02225	COG0475	glutathione-regulated potassium exporter activity
DNH82_RS02230	COG3842	ATPase activity
DNH82_RS02240	COG1175	transmembrane transport
DNH82_RS02245	COG3833	ABC-type maltose transport systems, permease component
DNH82_RS02255	COG0366	Alpha amylase catalytic
DNH82_RS02265	COG0673	inositol 2-dehydrogenase activity
DNH82_RS02275	COG1609	Transcriptional regulator
DNH82_RS02300	COG0431	NADPH-dependent FMN reductase
DNH82_RS02320	COG1131	(ABC) transporter
DNH82_RS02325	COG0842	Transport permease protein
DNH82_RS02330	COG2203	Gaf domain
DNH82_RS02330	COG4585	Histidine kinase
DNH82_RS02335	COG2197	response regulator
DNH82_RS02350	COG2235	arginine
DNH82_RS02370	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DNH82_RS02375	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
DNH82_RS02385	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DNH82_RS02390	COG3177	Filamentation induced by cAMP protein fic
DNH82_RS02395	COG3655	Transcriptional regulator
DNH82_RS02405	COG2130	NADP-dependent
DNH82_RS02410	COG0702	epimerase
DNH82_RS02425	COG0415	Belongs to the DNA photolyase family
DNH82_RS02435	COG2723	6-phospho-beta-galactosidase activity
DNH82_RS02440	COG2188	Transcriptional regulator
DNH82_RS02455	COG3655	Transcriptional regulator
DNH82_RS02470	COG2217	Heavy metal translocating P-type atpase
DNH82_RS02475	COG0531	amino acid
DNH82_RS02520	COG2801	Transposase and inactivated derivatives
DNH82_RS02530	COG1388	LysM domain
DNH82_RS02535	COG2217	Heavy metal translocating P-type atpase
DNH82_RS02545	COG0584	glycerophosphoryl diester phosphodiesterase
DNH82_RS02550	COG2030	dehydratase
DNH82_RS02575	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DNH82_RS02580	COG0640	Transcriptional regulator
DNH82_RS02590	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
DNH82_RS02595	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
DNH82_RS02605	COG4863	YycH protein
DNH82_RS02610	COG5002	protein histidine kinase activity
DNH82_RS02615	COG0745	RESPONSE REGULATOR receiver
DNH82_RS02635	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DNH82_RS02640	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
DNH82_RS02645	COG0305	Participates in initiation and elongation during chromosome replication
DNH82_RS02650	COG0359	binds to the 23S rRNA
DNH82_RS02655	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
DNH82_RS02660	COG4241	membrane
DNH82_RS02665	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
DNH82_RS02675	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
DNH82_RS02685	COG2986	histidine ammonia-lyase
DNH82_RS02690	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
DNH82_RS02700	COG0187	DNA topoisomerase II activity
DNH82_RS02705	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
DNH82_RS02710	COG2501	S4 domain
DNH82_RS02715	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
DNH82_RS02715	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
DNH82_RS02720	COG0592	DNA-directed DNA polymerase activity
DNH82_RS02725	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
DNH82_RS02735	COG0594	ribonuclease P activity
DNH82_RS02740	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
DNH82_RS02745	COG0445	tRNA wobble uridine modification
DNH82_RS02750	COG0357	Ribosomal RNA small subunit methyltransferase G
DNH82_RS02775	COG0400	carboxylic ester hydrolase activity
DNH82_RS02780	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
DNH82_RS02785	COG0346	lactoylglutathione lyase activity
DNH82_RS02790	COG1846	Transcriptional regulator
DNH82_RS02795	COG2388	GCN5-related N-acetyl-transferase
DNH82_RS02805	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
DNH82_RS02810	COG0830	nickel cation binding
DNH82_RS02820	COG0829	nickel cation binding
DNH82_RS02830	COG0646	methionine synthase
DNH82_RS02830	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
DNH82_RS02835	COG0626	cystathionine gamma-synthase activity
DNH82_RS02840	COG0626	cystathionine gamma-synthase activity
DNH82_RS02845	COG1475	DNA binding
DNH82_RS02850	COG0668	transmembrane transport
DNH82_RS02855	COG4481	Protein conserved in bacteria
DNH82_RS02860	COG0012	GTP binding
DNH82_RS02890	COG1131	(ABC) transporter
DNH82_RS02895	COG1668	transmembrane transport
DNH82_RS02905	COG0360	Binds together with S18 to 16S ribosomal RNA
DNH82_RS02915	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
DNH82_RS02925	COG0753	catalase activity
DNH82_RS02930	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
DNH82_RS02935	COG1464	Belongs to the NlpA lipoprotein family
DNH82_RS02940	COG2011	ABC-type metal ion transport system permease component
DNH82_RS02945	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
DNH82_RS02955	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
DNH82_RS02970	COG0450	alkyl hydroperoxide reductase
DNH82_RS02975	COG0778	Nitroreductase
DNH82_RS02995	COG0577	efflux transmembrane transporter activity
DNH82_RS02995	COG1136	(ABC) transporter
DNH82_RS03000	COG1823	symporter activity
DNH82_RS03005	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DNH82_RS03010	COG5183	chlorophyll binding
DNH82_RS03025	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
DNH82_RS03030	COG2233	PERMEase
DNH82_RS03035	COG0517	IMP dehydrogenase activity
DNH82_RS03035	COG0516	GMP reductase activity
DNH82_RS03040	COG0519	Catalyzes the synthesis of GMP from XMP
DNH82_RS03040	COG0518	GMP synthase (glutamine-hydrolyzing) activity
DNH82_RS03050	COG1525	nuclease
DNH82_RS03070	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
DNH82_RS03095	COG0747	negative chemotaxis
DNH82_RS03100	COG0601	transmembrane transport
DNH82_RS03105	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DNH82_RS03110	COG0444	Belongs to the ABC transporter superfamily
DNH82_RS03115	COG1124	(ABC) transporter
DNH82_RS03140	COG3682	Transcriptional regulator
DNH82_RS03160	COG2814	Major facilitator Superfamily
DNH82_RS03165	COG0730	response to heat
DNH82_RS03170	COG1937	Protein conserved in bacteria
DNH82_RS03175	COG2210	Belongs to the sulfur carrier protein TusA family
DNH82_RS03195	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DNH82_RS03195	COG1263	PTS System
DNH82_RS03200	COG1486	melibiose metabolic process
DNH82_RS03210	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
DNH82_RS03250	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
DNH82_RS03265	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
DNH82_RS03270	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
DNH82_RS03280	COG2205	protein histidine kinase activity
DNH82_RS03285	COG0745	RESPONSE REGULATOR receiver
DNH82_RS03295	COG0733	neurotransmitter:sodium symporter activity
DNH82_RS03300	COG2272	Belongs to the type-B carboxylesterase lipase family
DNH82_RS03305	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
DNH82_RS03310	COG0626	cystathionine gamma-synthase activity
DNH82_RS03335	COG1192	Involved in chromosome partitioning
DNH82_RS03355	COG2226	methyltransferase
DNH82_RS03365	COG0456	acetyltransferase
DNH82_RS03375	COG2378	regulation of single-species biofilm formation
DNH82_RS03380	COG1192	Involved in chromosome partitioning
DNH82_RS03465	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
DNH82_RS03485	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
DNH82_RS03500	COG0583	DNA-binding transcription factor activity
DNH82_RS03505	COG0067	glutamate synthase
DNH82_RS03505	COG0070	glutamate synthase
DNH82_RS03505	COG0069	glutamate synthase activity
DNH82_RS03510	COG0493	'glutamate synthase
DNH82_RS03520	COG1263	PTS System
DNH82_RS03520	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DNH82_RS03525	COG0366	Alpha amylase catalytic
DNH82_RS03530	COG2188	Transcriptional regulator
DNH82_RS03540	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
DNH82_RS03545	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
DNH82_RS03550	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
DNH82_RS03555	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
DNH82_RS03580	COG1982	Orn Lys Arg decarboxylase major
DNH82_RS03585	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
DNH82_RS03590	COG3870	Protein conserved in bacteria
DNH82_RS03595	COG0470	DNA polymerase III
DNH82_RS03600	COG1774	PSP1 C-terminal conserved region
DNH82_RS03605	COG4467	Involved in initiation control of chromosome replication
DNH82_RS03610	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
DNH82_RS03615	COG2827	Endonuclease containing a URI domain
DNH82_RS03620	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
DNH82_RS03630	COG0084	hydrolase, TatD family'
DNH82_RS03635	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
DNH82_RS03645	COG4466	Protein conserved in bacteria
DNH82_RS03650	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
DNH82_RS03655	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
DNH82_RS03660	COG0251	oxidation-reduction process
DNH82_RS03665	COG2088	sporulation resulting in formation of a cellular spore
DNH82_RS03670	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
DNH82_RS03675	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
DNH82_RS03685	COG0193	aminoacyl-tRNA hydrolase activity
DNH82_RS03690	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
DNH82_RS03695	COG2244	polysaccharide biosynthetic process
DNH82_RS03700	COG3956	TIGRFAM MazG family protein
DNH82_RS03705	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
DNH82_RS03715	COG1098	S1 RNA binding domain
DNH82_RS03730	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DNH82_RS03735	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
DNH82_RS03745	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
DNH82_RS03755	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
DNH82_RS03760	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
DNH82_RS03850	COG1289	transmembrane transporter activity
DNH82_RS03855	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DNH82_RS03860	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
DNH82_RS03865	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
DNH82_RS03875	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
DNH82_RS03885	COG3880	PFAM UvrB UvrC protein
DNH82_RS03890	COG3869	Catalyzes the specific phosphorylation of arginine residues in
DNH82_RS03895	COG0542	response to heat
DNH82_RS03930	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
DNH82_RS03935	COG4956	integral membrane protein (PIN domain superfamily)
DNH82_RS03940	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
DNH82_RS03950	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DNH82_RS03955	COG1045	serine acetyltransferase
DNH82_RS03960	COG0215	cysteine-tRNA ligase activity
DNH82_RS03965	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
DNH82_RS03985	COG0267	Belongs to the bacterial ribosomal protein bL33 family
DNH82_RS03990	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
DNH82_RS03995	COG0250	Participates in transcription elongation, termination and antitermination
DNH82_RS04000	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
DNH82_RS04005	COG0081	regulation of translation
DNH82_RS04010	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
DNH82_RS04020	COG2813	Specifically methylates the guanine in position
DNH82_RS04025	COG0085	RNA polymerase activity
DNH82_RS04030	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
DNH82_RS04040	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
DNH82_RS04045	COG0049	tRNA binding
DNH82_RS04050	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
DNH82_RS04055	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
DNH82_RS04060	COG3527	Alpha-acetolactate decarboxylase
DNH82_RS04065	COG1473	amidohydrolase
DNH82_RS04075	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DNH82_RS04105	COG0546	phosphoglycolate phosphatase activity
DNH82_RS04110	COG1428	Deoxynucleoside kinase
DNH82_RS04115	COG1428	Deoxynucleoside kinase
DNH82_RS04125	COG0561	phosphatase activity
DNH82_RS04140	COG0577	efflux transmembrane transporter activity
DNH82_RS04140	COG1136	(ABC) transporter
DNH82_RS04145	COG1469	GTP cyclohydrolase I activity
DNH82_RS04150	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
DNH82_RS04165	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DNH82_RS04165	COG2190	(PTS) system
DNH82_RS04165	COG1263	PTS System
DNH82_RS04180	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
DNH82_RS04190	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
DNH82_RS04245	COG0741	lytic transglycosylase activity
DNH82_RS04245	COG0791	NLP P60 protein
DNH82_RS04275	COG2946	Replication initiation factor
DNH82_RS04285	COG1674	ftsk spoiiie
DNH82_RS04300	COG2814	Major facilitator Superfamily
DNH82_RS04310	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
DNH82_RS04320	COG0488	(ABC) transporter
DNH82_RS04325	COG0588	phosphoglycerate mutase activity
DNH82_RS04330	COG0318	PFAM AMP-dependent synthetase and ligase
DNH82_RS04335	COG0183	Belongs to the thiolase family
DNH82_RS04365	COG2363	Small membrane protein
DNH82_RS04400	COG2311	Membrane
DNH82_RS04410	COG1566	PFAM secretion protein HlyD family protein
DNH82_RS04415	COG2814	Major facilitator Superfamily
DNH82_RS04425	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
DNH82_RS04430	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DNH82_RS04455	COG0095	Lipoate-protein ligase
DNH82_RS04460	COG0280	phosphate acetyltransferase
DNH82_RS04485	COG0471	metal ion transport
DNH82_RS04555	COG4844	belongs to the
DNH82_RS04565	COG1078	dGTPase activity
DNH82_RS04580	COG0018	arginyl-trna synthetase
DNH82_RS04590	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
DNH82_RS04595	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
DNH82_RS04600	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DNH82_RS04605	COG0546	phosphoglycolate phosphatase activity
DNH82_RS04655	COG2111	Na H antiporter
DNH82_RS04655	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
DNH82_RS04660	COG2111	Na H antiporter
DNH82_RS04665	COG1006	Multisubunit Na H antiporter MnhC subunit
DNH82_RS04675	COG1863	multisubunit Na H antiporter MnhE subunit
DNH82_RS04680	COG2212	antiporter activity
DNH82_RS04685	COG1320	monovalent cation:proton antiporter activity
DNH82_RS04690	COG0803	Belongs to the bacterial solute-binding protein 9 family
DNH82_RS04695	COG1108	ABC-type Mn2 Zn2 transport systems permease components
DNH82_RS04700	COG1121	(ABC) transporter
DNH82_RS04710	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DNH82_RS04715	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DNH82_RS04720	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
DNH82_RS04730	COG2423	ornithine cyclodeaminase activity
DNH82_RS04735	COG4264	IucA IucC family
DNH82_RS04740	COG2814	Major facilitator Superfamily
DNH82_RS04745	COG4264	IucA IucC family
DNH82_RS04750	COG4264	IucA IucC family
DNH82_RS04760	COG0019	diaminopimelate decarboxylase activity
DNH82_RS04765	COG1475	DNA binding
DNH82_RS04780	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
DNH82_RS04790	COG1682	transport, permease protein
DNH82_RS04795	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
DNH82_RS04800	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
DNH82_RS04815	COG1686	Belongs to the peptidase S11 family
DNH82_RS04820	COG1132	(ABC) transporter
DNH82_RS04840	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
DNH82_RS04845	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DNH82_RS04850	COG1120	ATPase activity
DNH82_RS04855	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DNH82_RS04860	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DNH82_RS04870	COG0477	Major facilitator Superfamily
DNH82_RS04875	COG3949	Membrane
DNH82_RS04885	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DNH82_RS04890	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DNH82_RS04895	COG0745	RESPONSE REGULATOR receiver
DNH82_RS04905	COG1136	(ABC) transporter
DNH82_RS04910	COG0577	efflux transmembrane transporter activity
DNH82_RS04915	COG1392	Phosphate transport regulator
DNH82_RS04920	COG0306	phosphate transporter
DNH82_RS04925	COG3942	CHAP domain
DNH82_RS04925	COG1388	LysM domain
DNH82_RS04935	COG0352	thiamine-phosphate diphosphorylase activity
DNH82_RS04945	COG2022	thiamine diphosphate biosynthetic process
DNH82_RS04950	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
DNH82_RS04955	COG0217	transcriptional regulatory protein
DNH82_RS04970	COG0583	DNA-binding transcription factor activity
DNH82_RS04975	COG2814	Major facilitator Superfamily
DNH82_RS04980	COG2839	Protein conserved in bacteria
DNH82_RS05010	COG1611	Belongs to the LOG family
DNH82_RS05015	COG1671	Belongs to the UPF0178 family
DNH82_RS05025	COG1968	undecaprenyl-diphosphatase activity
DNH82_RS05030	COG4988	ABC transporter
DNH82_RS05035	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
DNH82_RS05045	COG0523	cobalamin synthesis protein
DNH82_RS05050	COG4989	oxidoreductase activity
DNH82_RS05070	COG0039	L-malate dehydrogenase activity
DNH82_RS05090	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
DNH82_RS05095	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
DNH82_RS05110	COG1349	DNA-binding transcription factor activity
DNH82_RS05115	COG1105	Belongs to the carbohydrate kinase PfkB family
DNH82_RS05120	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DNH82_RS05120	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DNH82_RS05120	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DNH82_RS05125	COG1253	flavin adenine dinucleotide binding
DNH82_RS05130	COG0463	Glycosyl transferase, family 2
DNH82_RS05145	COG0602	queuosine metabolic process
DNH82_RS05150	COG0720	synthase
DNH82_RS05160	COG0512	Glutamine amidotransferase of anthranilate synthase
DNH82_RS05180	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
DNH82_RS05190	COG1368	sulfuric ester hydrolase activity
DNH82_RS05200	COG0488	(ABC) transporter
DNH82_RS05205	COG0514	ATP-dependent DNA helicase (RecQ)
DNH82_RS05210	COG1125	glycine betaine transport
DNH82_RS05210	COG0517	IMP dehydrogenase activity
DNH82_RS05215	COG1174	glycine betaine transport
DNH82_RS05220	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
DNH82_RS05235	COG3104	oligopeptide transport
DNH82_RS05240	COG3104	oligopeptide transport
DNH82_RS05255	COG2801	Transposase and inactivated derivatives
DNH82_RS05300	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DNH82_RS05305	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DNH82_RS05315	COG0812	UDP-N-acetylmuramate dehydrogenase activity
DNH82_RS05330	COG3118	belongs to the thioredoxin family
DNH82_RS05335	COG1929	Belongs to the glycerate kinase type-1 family
DNH82_RS05345	COG2195	Cleaves the N-terminal amino acid of tripeptides
DNH82_RS05365	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DNH82_RS05370	COG1739	Uncharacterized protein family UPF0029
DNH82_RS05380	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
DNH82_RS05395	COG0653	protein targeting
DNH82_RS05430	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
DNH82_RS05435	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
DNH82_RS05440	COG0110	maltose O-acetyltransferase activity
DNH82_RS05455	COG1660	Displays ATPase and GTPase activities
DNH82_RS05460	COG0391	Required for morphogenesis under gluconeogenic growth conditions
DNH82_RS05465	COG1481	regulation of sporulation
DNH82_RS05475	COG0740	serine-type endopeptidase activity
DNH82_RS05485	COG1090	epimerase
DNH82_RS05505	COG0126	phosphoglycerate kinase activity
DNH82_RS05510	COG0149	triose-phosphate isomerase activity
DNH82_RS05515	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
DNH82_RS05520	COG0148	phosphopyruvate hydratase activity
DNH82_RS05530	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
DNH82_RS05535	COG1647	Serine aminopeptidase, S33
DNH82_RS05540	COG0557	exoribonuclease II activity
DNH82_RS05570	COG0346	lactoylglutathione lyase activity
DNH82_RS05590	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
DNH82_RS05605	COG1764	response to oxidative stress
DNH82_RS05615	COG0710	3-dehydroquinate dehydratase activity
DNH82_RS05625	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DNH82_RS05630	COG1393	Belongs to the ArsC family
DNH82_RS05640	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
DNH82_RS05645	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DNH82_RS05655	COG2011	ABC-type metal ion transport system permease component
DNH82_RS05660	COG1464	Belongs to the NlpA lipoprotein family
DNH82_RS05665	COG1464	Belongs to the NlpA lipoprotein family
DNH82_RS05675	COG0396	ATPase activity
DNH82_RS05680	COG0719	Fe-S assembly protein
DNH82_RS05690	COG0822	iron-sulfur transferase activity
DNH82_RS05695	COG0719	Fe-S assembly protein
DNH82_RS05705	COG1253	flavin adenine dinucleotide binding
DNH82_RS05720	COG1801	Protein of unknown function DUF72
DNH82_RS05725	COG0730	response to heat
DNH82_RS05730	COG0737	Belongs to the 5'-nucleotidase family
DNH82_RS05735	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
DNH82_RS05740	COG4470	Protein conserved in bacteria
DNH82_RS05750	COG2445	Protein of unknown function DUF86
DNH82_RS05755	COG0647	UMP catabolic process
DNH82_RS05760	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DNH82_RS05765	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
DNH82_RS05770	COG4837	Protein of unknown function (DUF1462)
DNH82_RS05775	COG1252	NADH dehydrogenase
DNH82_RS05780	COG4844	belongs to the
DNH82_RS05785	COG0316	Belongs to the HesB IscA family
DNH82_RS05790	COG1252	NADH dehydrogenase
DNH82_RS05795	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
DNH82_RS05800	COG2056	Na+-H+ antiporter family
DNH82_RS05810	COG1320	monovalent cation:proton antiporter activity
DNH82_RS05815	COG2212	antiporter activity
DNH82_RS05820	COG1863	multisubunit Na H antiporter MnhE subunit
DNH82_RS05825	COG0651	ATP synthesis coupled electron transport
DNH82_RS05830	COG1006	Multisubunit Na H antiporter MnhC subunit
DNH82_RS05835	COG2111	Na H antiporter
DNH82_RS05840	COG2111	Na H antiporter
DNH82_RS05840	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
DNH82_RS05850	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
DNH82_RS05870	COG1278	Cold shock
DNH82_RS05880	COG1098	S1 RNA binding domain
DNH82_RS05885	COG1012	belongs to the aldehyde dehydrogenase family
DNH82_RS05900	COG0584	glycerophosphoryl diester phosphodiesterase
DNH82_RS05910	COG0137	argininosuccinate synthase activity
DNH82_RS05915	COG0166	Belongs to the GPI family
DNH82_RS05930	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
DNH82_RS05940	COG0179	Fumarylacetoacetate (FAA) hydrolase
DNH82_RS05950	COG0446	pyridine nucleotide-disulphide oxidoreductase
DNH82_RS05955	COG0561	phosphatase activity
DNH82_RS05975	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
DNH82_RS06000	COG0601	transmembrane transport
DNH82_RS06005	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DNH82_RS06010	COG0444	Belongs to the ABC transporter superfamily
DNH82_RS06015	COG4608	Belongs to the ABC transporter superfamily
DNH82_RS06020	COG4166	transmembrane transport
DNH82_RS06025	COG0180	Tryptophanyl-tRNA synthetase
DNH82_RS06030	COG1393	Belongs to the ArsC family
DNH82_RS06040	COG3591	Belongs to the peptidase S1B family
DNH82_RS06055	COG1164	Oligoendopeptidase f
DNH82_RS06065	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
DNH82_RS06070	COG2346	COG2346, Truncated hemoglobins
DNH82_RS06085	COG2357	RelA SpoT domain protein
DNH82_RS06095	COG0564	pseudouridine synthase activity
DNH82_RS06100	COG2239	Acts as a magnesium transporter
DNH82_RS06105	COG0475	glutathione-regulated potassium exporter activity
DNH82_RS06105	COG0569	domain protein
DNH82_RS06115	COG0673	inositol 2-dehydrogenase activity
DNH82_RS06120	COG2211	Major facilitator Superfamily
DNH82_RS06125	COG4409	exo-alpha-(2->6)-sialidase activity
DNH82_RS06130	COG0628	permease
DNH82_RS06135	COG1115	amino acid carrier protein
DNH82_RS06140	COG2382	esterase
DNH82_RS06145	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
DNH82_RS06150	COG3716	PTS system mannose fructose sorbose family IID component
DNH82_RS06155	COG3715	PTS system
DNH82_RS06165	COG2814	Major facilitator Superfamily
DNH82_RS06170	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
DNH82_RS06175	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
DNH82_RS06185	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
DNH82_RS06190	COG0861	Integral membrane protein TerC family
DNH82_RS06195	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DNH82_RS06200	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
DNH82_RS06205	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
DNH82_RS06215	COG1696	Membrane protein involved in D-alanine export
DNH82_RS06220	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DNH82_RS06235	COG3266	domain, Protein
DNH82_RS06235	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
DNH82_RS06235	COG4932	domain protein
DNH82_RS06265	COG4873	Protein conserved in bacteria
DNH82_RS06285	COG4619	ABC transporter
DNH82_RS06290	COG0390	transport system, permease component
DNH82_RS06295	COG1575	Belongs to the MenA family. Type 1 subfamily
DNH82_RS06300	COG1169	isochorismate synthase
DNH82_RS06305	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
DNH82_RS06315	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
DNH82_RS06320	COG0436	Aminotransferase
DNH82_RS06325	COG3594	Acyltransferase
DNH82_RS06350	COG1316	TRANSCRIPTIONal
DNH82_RS06355	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DNH82_RS06360	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
DNH82_RS06370	COG1215	transferase activity, transferring glycosyl groups
DNH82_RS06380	COG1682	transport, permease protein
DNH82_RS06390	COG1134	teichoic acid transport
DNH82_RS06405	COG3212	peptidase
DNH82_RS06445	COG3973	AAA domain
DNH82_RS06455	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
DNH82_RS06460	COG1845	cytochrome c oxidase, subunit III
DNH82_RS06470	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
DNH82_RS06480	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
DNH82_RS06480	COG1017	nitric oxide dioxygenase activity
DNH82_RS06485	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
DNH82_RS06490	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
DNH82_RS06495	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
DNH82_RS06500	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
DNH82_RS06505	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
DNH82_RS06510	COG0047	phosphoribosylformylglycinamidine synthase activity
DNH82_RS06520	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
DNH82_RS06525	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
DNH82_RS06535	COG0138	bifunctional purine biosynthesis protein purh
DNH82_RS06540	COG0151	Belongs to the GarS family
DNH82_RS06550	COG4172	Belongs to the ABC transporter superfamily
DNH82_RS06565	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
DNH82_RS06575	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
DNH82_RS06580	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DNH82_RS06590	COG1393	Belongs to the ArsC family
DNH82_RS06595	COG1271	oxidase subunit
DNH82_RS06600	COG1294	oxidase, subunit
DNH82_RS06605	COG0569	domain protein
DNH82_RS06630	COG0492	ferredoxin-NADP+ reductase activity
DNH82_RS06640	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
DNH82_RS06645	COG5503	Protein of unknown function (DUF1447)
DNH82_RS06700	COG4476	Belongs to the UPF0223 family
DNH82_RS06710	COG3842	ATPase activity
DNH82_RS06720	COG1177	transmembrane transport
DNH82_RS06725	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
DNH82_RS06740	COG4493	Belongs to the UPF0637 family
DNH82_RS06745	COG0483	inositol monophosphate 1-phosphatase activity
DNH82_RS06755	COG1217	gtp-binding protein TYPA
DNH82_RS06760	COG1902	pentaerythritol trinitrate reductase activity
DNH82_RS06765	COG4896	Protein conserved in bacteria
DNH82_RS06770	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
DNH82_RS06775	COG4838	Belongs to the UPF0358 family
DNH82_RS06780	COG0772	Belongs to the SEDS family
DNH82_RS06795	COG0109	protoheme IX farnesyltransferase activity
DNH82_RS06810	COG3679	Belongs to the UPF0342 family
DNH82_RS06815	COG0584	glycerophosphoryl diester phosphodiesterase
DNH82_RS06820	COG4471	UPF0298 protein
DNH82_RS06830	COG0742	ribosomal rna small subunit methyltransferase
DNH82_RS06850	COG0333	Belongs to the bacterial ribosomal protein bL32 family
DNH82_RS06855	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DNH82_RS06860	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
DNH82_RS06875	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
DNH82_RS06890	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
DNH82_RS06890	COG1796	DNA polymerase
DNH82_RS06895	COG1193	negative regulation of DNA recombination
DNH82_RS06900	COG3118	belongs to the thioredoxin family
DNH82_RS06905	COG0322	excinuclease ABC activity
DNH82_RS06910	COG2009	succinate dehydrogenase
DNH82_RS06915	COG1053	succinate dehydrogenase
DNH82_RS06920	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
DNH82_RS06925	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
DNH82_RS06980	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
DNH82_RS06995	COG1011	Hydrolase
DNH82_RS07000	COG0454	-acetyltransferase
DNH82_RS07005	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
DNH82_RS07010	COG2001	Belongs to the MraZ family
DNH82_RS07015	COG0275	rRNA processing
DNH82_RS07020	COG4839	cell division protein FtsL
DNH82_RS07025	COG0768	penicillin binding
DNH82_RS07035	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
DNH82_RS07045	COG0849	cell division
DNH82_RS07050	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
DNH82_RS07060	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
DNH82_RS07065	COG1799	cell septum assembly
DNH82_RS07070	COG0762	integral membrane protein
DNH82_RS07075	COG1869	D-ribose catabolic process
DNH82_RS07080	COG4975	Glucose uptake
DNH82_RS07090	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DNH82_RS07095	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DNH82_RS07110	COG3599	regulation of cell shape
DNH82_RS07115	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
DNH82_RS07120	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
DNH82_RS07125	COG0564	pseudouridine synthase activity
DNH82_RS07130	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
DNH82_RS07150	COG0505	Belongs to the CarA family
DNH82_RS07155	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
DNH82_RS07165	COG0167	dihydroorotate dehydrogenase activity
DNH82_RS07170	COG0284	orotidine-5'-phosphate decarboxylase activity
DNH82_RS07175	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
DNH82_RS07195	COG1758	RNA polymerase activity
DNH82_RS07200	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
DNH82_RS07205	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
DNH82_RS07210	COG0242	peptide deformylase activity
DNH82_RS07215	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
DNH82_RS07220	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
DNH82_RS07220	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
DNH82_RS07225	COG0820	rRNA (adenine-C2-)-methyltransferase activity
DNH82_RS07240	COG2124	cytochrome p450
DNH82_RS07250	COG1162	GTPase activity
DNH82_RS07270	COG1302	Protein conserved in bacteria
DNH82_RS07280	COG1760	l-serine dehydratase
DNH82_RS07285	COG1760	l-serine dehydratase
DNH82_RS07295	COG1349	DNA-binding transcription factor activity
DNH82_RS07300	COG0416	fatty acid biosynthetic process
DNH82_RS07315	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DNH82_RS07320	COG0571	ribonuclease III activity
DNH82_RS07325	COG1196	nuclear chromosome segregation
DNH82_RS07330	COG0552	protein localization to endoplasmic reticulum
DNH82_RS07335	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
DNH82_RS07340	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
DNH82_RS07360	COG1401	restriction endodeoxyribonuclease activity
DNH82_RS07370	COG0228	four-way junction DNA binding
DNH82_RS07375	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
DNH82_RS07380	COG0336	Belongs to the RNA methyltransferase TrmD family
DNH82_RS07420	COG4485	Bacterial membrane protein, YfhO
DNH82_RS07435	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
DNH82_RS07445	COG0045	succinate-CoA ligase (ADP-forming) activity
DNH82_RS07455	COG0758	DNA mediated transformation
DNH82_RS07460	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
DNH82_RS07465	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
DNH82_RS07470	COG4974	Belongs to the 'phage' integrase family
DNH82_RS07475	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
DNH82_RS07480	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
DNH82_RS07485	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
DNH82_RS07490	COG0052	Belongs to the universal ribosomal protein uS2 family
DNH82_RS07495	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
DNH82_RS07500	COG0528	UMP kinase activity
DNH82_RS07505	COG0233	cytoplasmic translational termination
DNH82_RS07510	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
DNH82_RS07515	COG4589	Belongs to the CDS family
DNH82_RS07520	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
DNH82_RS07530	COG0442	prolyl-tRNA aminoacylation
DNH82_RS07540	COG0779	Required for maturation of 30S ribosomal subunits
DNH82_RS07545	COG0195	Participates in both transcription termination and antitermination
DNH82_RS07550	COG2740	Nucleic-acid-binding protein implicated in transcription termination
DNH82_RS07555	COG1358	cellular component organization or biogenesis
DNH82_RS07560	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
DNH82_RS07570	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
DNH82_RS07575	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
DNH82_RS07580	COG0196	riboflavin kinase activity
DNH82_RS07590	COG1185	polyribonucleotide nucleotidyltransferase activity
DNH82_RS07610	COG0612	Peptidase, M16
DNH82_RS07615	COG0612	Peptidase, M16
DNH82_RS07620	COG0300	oxidoreductase activity
DNH82_RS07640	COG1546	Belongs to the CinA family
DNH82_RS07640	COG1058	Belongs to the CinA family
DNH82_RS07645	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
DNH82_RS07650	COG1418	mRNA catabolic process
DNH82_RS07670	COG1692	metallophosphoesterase
DNH82_RS07675	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
DNH82_RS07675	COG0674	pyruvate-flavodoxin oxidoreductase activity
DNH82_RS07680	COG1013	pyruvate-flavodoxin oxidoreductase activity
DNH82_RS07690	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
DNH82_RS07710	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
DNH82_RS07715	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
DNH82_RS07720	COG1619	proteins homologs of microcin C7 resistance protein MccF
DNH82_RS07725	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
DNH82_RS07735	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
DNH82_RS07740	COG1923	regulation of RNA biosynthetic process
DNH82_RS07745	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
DNH82_RS07750	COG2267	carboxylic ester hydrolase activity
DNH82_RS07755	COG0386	Belongs to the glutathione peroxidase family
DNH82_RS07760	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
DNH82_RS07765	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
DNH82_RS07770	COG0789	Transcriptional regulator
DNH82_RS07850	COG0584	glycerophosphoryl diester phosphodiesterase
DNH82_RS07880	COG1525	nuclease
DNH82_RS07900	COG0527	aspartate kinase activity
DNH82_RS07905	COG0460	homoserine dehydrogenase
DNH82_RS07910	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
DNH82_RS07915	COG0083	homoserine kinase activity
DNH82_RS07930	COG0833	amino acid
DNH82_RS07940	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
DNH82_RS07945	COG0516	GMP reductase activity
DNH82_RS07955	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
DNH82_RS07965	COG4224	UPF0291 protein
DNH82_RS07975	COG3763	UPF0154 protein
DNH82_RS07980	COG4846	Membrane protein involved in cytochrome C biogenesis
DNH82_RS07985	COG0420	3'-5' exonuclease activity
DNH82_RS07990	COG0419	ATPase involved in DNA repair
DNH82_RS07995	COG1970	mechanosensitive ion channel activity
DNH82_RS08000	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
DNH82_RS08010	COG0824	Thioesterase
DNH82_RS08015	COG4841	protein insertion into membrane
DNH82_RS08020	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
DNH82_RS08030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
DNH82_RS08035	COG1115	amino acid carrier protein
DNH82_RS08040	COG3711	transcriptional antiterminator
DNH82_RS08050	COG0628	permease
DNH82_RS08070	COG1942	4-Oxalocrotonate Tautomerase
DNH82_RS08080	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DNH82_RS08085	COG0287	Prephenate dehydrogenase
DNH82_RS08090	COG1363	Peptidase, m42
DNH82_RS08120	COG2996	Protein conserved in bacteria
DNH82_RS08125	COG0488	(ABC) transporter
DNH82_RS08130	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
DNH82_RS08135	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DNH82_RS08140	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
DNH82_RS08145	COG2171	N-acyltransferase activity
DNH82_RS08150	COG1473	amidohydrolase
DNH82_RS08170	COG1278	Cold shock
DNH82_RS08190	COG3853	Toxic anion resistance protein (TelA)
DNH82_RS08200	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
DNH82_RS08205	COG1114	Component of the transport system for branched-chain amino acids
DNH82_RS08210	COG4548	von Willebrand factor, type A
DNH82_RS08215	COG0714	Associated with various cellular activities
DNH82_RS08240	COG0567	Dehydrogenase, E1 component
DNH82_RS08245	COG5002	protein histidine kinase activity
DNH82_RS08255	COG0671	phosphoesterase, PA-phosphatase related
DNH82_RS08260	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
DNH82_RS08270	COG0793	Belongs to the peptidase S41A family
DNH82_RS08280	COG2190	(PTS) system
DNH82_RS08315	COG1413	lyase activity
DNH82_RS08325	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
DNH82_RS08335	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DNH82_RS08340	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
DNH82_RS08345	COG2962	Rard protein
DNH82_RS08350	COG0116	Belongs to the methyltransferase superfamily
DNH82_RS08360	COG3599	regulation of cell shape
DNH82_RS08365	COG4474	Belongs to the UPF0398 family
DNH82_RS08380	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DNH82_RS08380	COG4499	WXG100 protein secretion system (Wss), protein YukC
DNH82_RS08390	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
DNH82_RS08395	COG3935	DnaD domain protein
DNH82_RS08400	COG0017	Asparaginyl-tRNA synthetase
DNH82_RS08415	COG0617	tRNA 3'-terminal CCA addition
DNH82_RS08420	COG0438	transferase activity, transferring glycosyl groups
DNH82_RS08425	COG1694	Mazg nucleotide pyrophosphohydrolase
DNH82_RS08435	COG4347	Protein of unknown function (DUF1405)
DNH82_RS08440	COG5582	Belongs to the UPF0302 family
DNH82_RS08445	COG0457	Tetratricopeptide repeat
DNH82_RS08455	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
DNH82_RS08465	COG0105	UTP biosynthetic process
DNH82_RS08470	COG0142	geranyltranstransferase activity
DNH82_RS08490	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
DNH82_RS08495	COG1160	GTP binding
DNH82_RS08500	COG0539	negative regulation of cytoplasmic translation
DNH82_RS08510	COG0252	asparaginase activity
DNH82_RS08515	COG0492	ferredoxin-NADP+ reductase activity
DNH82_RS08525	COG0514	ATP-dependent DNA helicase (RecQ)
DNH82_RS08535	COG1141	Ferredoxin
DNH82_RS08550	COG0745	RESPONSE REGULATOR receiver
DNH82_RS08555	COG1187	pseudouridine synthase activity
DNH82_RS08560	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
DNH82_RS08565	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
DNH82_RS08580	COG0735	belongs to the Fur family
DNH82_RS08585	COG0494	nUDIX hydrolase
DNH82_RS08590	COG0667	Aldo Keto reductase
DNH82_RS08600	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
DNH82_RS08605	COG1234	tRNA 3'-trailer cleavage
DNH82_RS08610	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
DNH82_RS08640	COG2195	Cleaves the N-terminal amino acid of tripeptides
DNH82_RS08650	COG4129	membrane
DNH82_RS08660	COG0508	dehydrogenase complex catalyzes the overall conversion of
DNH82_RS08665	COG0022	dehydrogenase e1 component
DNH82_RS08670	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
DNH82_RS08675	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DNH82_RS08680	COG3426	butyrate kinase activity
DNH82_RS08685	COG0280	phosphate acetyltransferase
DNH82_RS08690	COG0497	DNA recombination
DNH82_RS08695	COG1438	arginine binding
DNH82_RS08700	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
DNH82_RS08705	COG0142	geranyltranstransferase activity
DNH82_RS08710	COG1722	exodeoxyribonuclease VII activity
DNH82_RS08715	COG1570	exodeoxyribonuclease VII activity
DNH82_RS08725	COG1302	Protein conserved in bacteria
DNH82_RS08730	COG0439	Biotin carboxylase
DNH82_RS08735	COG0511	ligase activity, forming carbon-carbon bonds
DNH82_RS08740	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
DNH82_RS08745	COG0006	proline dipeptidase activity
DNH82_RS08760	COG0095	Lipoate-protein ligase
DNH82_RS08765	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
DNH82_RS08770	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
DNH82_RS08780	COG0404	The glycine cleavage system catalyzes the degradation of glycine
DNH82_RS08785	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
DNH82_RS08815	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
DNH82_RS08820	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DNH82_RS08825	COG0011	TIGRFAM Protein of
DNH82_RS08830	COG1940	carbohydrate kinase activity
DNH82_RS08835	COG4483	Protein conserved in bacteria
DNH82_RS08840	COG0457	Tetratricopeptide repeat
DNH82_RS08840	COG0705	Rhomboid family
DNH82_RS08845	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
DNH82_RS08855	COG0704	Plays a role in the regulation of phosphate uptake
DNH82_RS08860	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
DNH82_RS08865	COG0581	inorganic phosphate transmembrane transporter activity
DNH82_RS08875	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
DNH82_RS08880	COG0768	penicillin binding
DNH82_RS08890	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
DNH82_RS08895	COG0735	belongs to the Fur family
DNH82_RS08900	COG1108	ABC-type Mn2 Zn2 transport systems permease components
DNH82_RS08905	COG1121	(ABC) transporter
DNH82_RS08910	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
DNH82_RS08915	COG0513	Belongs to the DEAD box helicase family
DNH82_RS08920	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
DNH82_RS08925	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
DNH82_RS08930	COG2384	SAM-dependent methyltransferase
DNH82_RS08935	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
DNH82_RS08940	COG0358	DNA primase activity
DNH82_RS08945	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
DNH82_RS08950	COG0517	IMP dehydrogenase activity
DNH82_RS08955	COG0423	glycine-tRNA ligase activity
DNH82_RS08960	COG1381	Involved in DNA repair and RecF pathway recombination
DNH82_RS08965	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
DNH82_RS08975	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
DNH82_RS08985	COG1702	phosphate starvation-inducible protein PhoH
DNH82_RS08995	COG4864	UPF0365 protein
DNH82_RS09000	COG1030	water channel activity
DNH82_RS09015	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
DNH82_RS09020	COG1385	rRNA (uridine-N3-)-methyltransferase activity
DNH82_RS09025	COG2264	protein methyltransferase activity
DNH82_RS09030	COG0484	heat shock protein binding
DNH82_RS09035	COG0443	Heat shock 70 kDa protein
DNH82_RS09050	COG0635	Involved in the biosynthesis of porphyrin-containing compound
DNH82_RS09060	COG0268	Binds directly to 16S ribosomal RNA
DNH82_RS09065	COG1466	dna polymerase III delta subunit
DNH82_RS09070	COG2333	competence protein COMEC
DNH82_RS09070	COG0658	competence protein
DNH82_RS09075	COG2131	deaminase
DNH82_RS09080	COG1596	polysaccharide export
DNH82_RS09080	COG1555	photosystem II stabilization
DNH82_RS09085	COG2226	methyltransferase
DNH82_RS09090	COG0799	negative regulation of ribosome biogenesis
DNH82_RS09095	COG1713	HD superfamily hydrolase involved in NAD metabolism
DNH82_RS09105	COG1534	Rna-binding protein
DNH82_RS09110	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
DNH82_RS09115	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
DNH82_RS09120	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
DNH82_RS09125	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
DNH82_RS09130	COG1914	H( )-stimulated, divalent metal cation uptake system
DNH82_RS09135	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
DNH82_RS09140	COG0439	Biotin carboxylase
DNH82_RS09145	COG0511	ligase activity, forming carbon-carbon bonds
DNH82_RS09150	COG1984	allophanate hydrolase subunit 2
DNH82_RS09155	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
DNH82_RS09165	COG0572	uridine kinase
DNH82_RS09170	COG0826	peptidase U32
DNH82_RS09175	COG0826	peptidase U32
DNH82_RS09180	COG4122	O-methyltransferase activity
DNH82_RS09185	COG3906	Belongs to the UPF0473 family
DNH82_RS09190	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
DNH82_RS09195	COG4472	Bacterial protein of unknown function (DUF965)
DNH82_RS09200	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
DNH82_RS09205	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
DNH82_RS09215	COG0482	sulfurtransferase activity
DNH82_RS09220	COG1104	cysteine desulfurase activity
DNH82_RS09225	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DNH82_RS09240	COG1959	2 iron, 2 sulfur cluster binding
DNH82_RS09245	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
DNH82_RS09250	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
DNH82_RS09260	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
DNH82_RS09270	COG0860	N-Acetylmuramoyl-L-alanine amidase
DNH82_RS09275	COG1490	D-aminoacyl-tRNA deacylase activity
DNH82_RS09285	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
DNH82_RS09290	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
DNH82_RS09290	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
DNH82_RS09295	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DNH82_RS09295	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DNH82_RS09300	COG1862	Preprotein translocase
DNH82_RS09310	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
DNH82_RS09320	COG0632	four-way junction helicase activity
DNH82_RS09330	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
DNH82_RS09340	COG2868	ribosomal protein
DNH82_RS09380	COG2003	Belongs to the UPF0758 family
DNH82_RS09390	COG0285	dihydrofolate synthase activity
DNH82_RS09395	COG0525	valine-tRNA ligase activity
DNH82_RS09400	COG2818	Glycosylase
DNH82_RS09410	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
DNH82_RS09425	COG0181	hydroxymethylbilane synthase activity
DNH82_RS09435	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
DNH82_RS09440	COG0218	Necessary for normal cell division and for the maintenance of normal septation
DNH82_RS09450	COG0544	peptidyl-prolyl cis-trans isomerase activity
DNH82_RS09465	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
DNH82_RS09470	COG0291	Belongs to the bacterial ribosomal protein bL35 family
DNH82_RS09475	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
DNH82_RS09485	COG0833	amino acid
DNH82_RS09495	COG1484	DNA-dependent DNA replication
DNH82_RS09500	COG3611	Membrane attachment protein
DNH82_RS09510	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
DNH82_RS09515	COG0237	dephospho-CoA kinase activity
DNH82_RS09525	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DNH82_RS09525	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DNH82_RS09530	COG5002	protein histidine kinase activity
DNH82_RS09535	COG0745	RESPONSE REGULATOR receiver
DNH82_RS09540	COG0538	isocitrate dehydrogenase activity
DNH82_RS09545	COG0372	Belongs to the citrate synthase family
DNH82_RS09550	COG0469	pyruvate kinase activity
DNH82_RS09555	COG0205	6-phosphofructokinase activity
DNH82_RS09560	COG0825	malonyl-CoA metabolic process
DNH82_RS09565	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
DNH82_RS09570	COG0281	malic enzyme
DNH82_RS09575	COG0587	DNA-directed DNA polymerase activity
DNH82_RS09580	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
DNH82_RS09585	COG4109	DRTGG domain
DNH82_RS09595	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
DNH82_RS09600	COG0006	proline dipeptidase activity
DNH82_RS09610	COG0686	Belongs to the AlaDH PNT family
DNH82_RS09615	COG0589	response to stress
DNH82_RS09620	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
DNH82_RS09625	COG0827	DNA restriction-modification system
DNH82_RS09630	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
DNH82_RS09635	COG1714	RDD family
DNH82_RS09640	COG0616	signal peptide processing
DNH82_RS09650	COG0301	tRNA thio-modification
DNH82_RS09655	COG1104	cysteine desulfurase activity
DNH82_RS09660	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
DNH82_RS09665	COG1956	GAF domain-containing protein
DNH82_RS09670	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
DNH82_RS09705	COG0456	acetyltransferase
DNH82_RS09740	COG1764	response to oxidative stress
DNH82_RS09745	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
DNH82_RS09750	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
DNH82_RS09760	COG0204	Acyl-transferase
DNH82_RS09765	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DNH82_RS09775	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
DNH82_RS09780	COG2759	Belongs to the formate--tetrahydrofolate ligase family
DNH82_RS09785	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DNH82_RS09790	COG0454	-acetyltransferase
DNH82_RS09800	COG1609	Transcriptional regulator
DNH82_RS09805	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
DNH82_RS09805	COG1605	Chorismate mutase
DNH82_RS09815	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
DNH82_RS09820	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
DNH82_RS09825	COG1674	ftsk spoiiie
DNH82_RS09830	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DNH82_RS09835	COG4848	Belongs to the UPF0354 family
DNH82_RS09840	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DNH82_RS09845	COG1363	Peptidase, m42
DNH82_RS09855	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DNH82_RS09860	COG0220	tRNA (guanine-N7-)-methyltransferase activity
DNH82_RS09865	COG0510	thiamine kinase activity
DNH82_RS09870	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
DNH82_RS09875	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DNH82_RS09890	COG2244	polysaccharide biosynthetic process
DNH82_RS09895	COG2081	HI0933 family
DNH82_RS09900	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
DNH82_RS09905	COG0495	leucyl-tRNA aminoacylation
DNH82_RS09910	COG2814	Major facilitator Superfamily
DNH82_RS09915	COG1242	4 iron, 4 sulfur cluster binding
DNH82_RS09920	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
DNH82_RS09930	COG0039	L-malate dehydrogenase activity
DNH82_RS09935	COG2267	carboxylic ester hydrolase activity
DNH82_RS09950	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
DNH82_RS09955	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
DNH82_RS09955	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
DNH82_RS09965	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
DNH82_RS09965	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
DNH82_RS09980	COG3266	domain, Protein
DNH82_RS09980	COG5632	N-Acetylmuramoyl-L-alanine amidase
DNH82_RS09980	COG4193	domain, Protein
DNH82_RS10005	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
DNH82_RS10015	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
DNH82_RS10020	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
DNH82_RS10025	COG0656	L-ascorbic acid biosynthetic process
DNH82_RS10035	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
DNH82_RS10045	COG1506	peptidase
DNH82_RS10050	COG0494	nUDIX hydrolase
DNH82_RS10055	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
DNH82_RS10075	COG0235	Class ii aldolase
DNH82_RS10080	COG3623	hexulose-6-phosphate isomerase
DNH82_RS10100	COG3037	sugar-specific permease SgaT UlaA
DNH82_RS10170	COG0582	viral genome integration into host DNA
DNH82_RS10220	COG3545	Serine hydrolase
DNH82_RS10225	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
DNH82_RS10235	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
DNH82_RS10250	COG4473	ABC transporter
DNH82_RS10255	COG1131	(ABC) transporter
DNH82_RS10260	COG0537	adenosine 5'-monophosphoramidase activity
DNH82_RS10270	COG1846	Transcriptional regulator
DNH82_RS10285	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
DNH82_RS10290	COG3481	metal-dependent phosphohydrolase, HD sub domain
DNH82_RS10300	COG0420	3'-5' exonuclease activity
DNH82_RS10305	COG3679	Belongs to the UPF0342 family
DNH82_RS10310	COG4399	Belongs to the UPF0754 family
DNH82_RS10325	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
DNH82_RS10330	COG2197	response regulator
DNH82_RS10335	COG4585	Histidine kinase
DNH82_RS10335	COG2203	Gaf domain
DNH82_RS10340	COG0564	pseudouridine synthase activity
DNH82_RS10345	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
DNH82_RS10350	COG0248	Ppx GppA phosphatase
DNH82_RS10355	COG0114	fumarate hydratase activity
DNH82_RS10370	COG0363	glucosamine-6-phosphate deaminase activity
DNH82_RS10380	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
DNH82_RS10385	COG1126	abc transporter atp-binding protein
DNH82_RS10390	COG0765	amino acid transport
DNH82_RS10555	COG0735	belongs to the Fur family
DNH82_RS10565	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
DNH82_RS10570	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
DNH82_RS10575	COG4129	membrane
DNH82_RS10580	COG0069	glutamate synthase activity
DNH82_RS10590	COG3557	Belongs to the UPF0374 family
DNH82_RS10595	COG1194	a g-specific adenine glycosylase
DNH82_RS10600	COG1988	membrane-bound metal-dependent
DNH82_RS10610	COG1134	teichoic acid transport
DNH82_RS10610	COG1388	LysM domain
DNH82_RS10620	COG2137	regulation of response to DNA damage stimulus
DNH82_RS10625	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DNH82_RS10630	COG0028	Belongs to the TPP enzyme family
DNH82_RS10635	COG0693	protein deglycase activity
DNH82_RS10645	COG0535	radical SAM domain protein
DNH82_RS10650	COG1607	acyl-coa hydrolase
DNH82_RS10655	COG2309	aminopeptidase activity
DNH82_RS10660	COG4840	Belongs to the UPF0435 family
DNH82_RS10675	COG1295	ribonuclease BN
DNH82_RS10680	COG0288	reversible hydration of carbon dioxide
DNH82_RS10705	COG0024	Methionine aminopeptidase
DNH82_RS10710	COG4129	membrane
DNH82_RS10725	COG1528	Iron-storage protein
DNH82_RS10735	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DNH82_RS10745	COG2211	Major facilitator Superfamily
DNH82_RS10760	COG0488	(ABC) transporter
DNH82_RS10785	COG1597	lipid kinase activity
DNH82_RS10790	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DNH82_RS10800	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DNH82_RS10805	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DNH82_RS10810	COG4851	CamS sex pheromone cAM373 precursor
DNH82_RS10815	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
DNH82_RS10820	COG0210	DNA helicase
DNH82_RS10825	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
DNH82_RS10830	COG4496	protein, YerC YecD
DNH82_RS10835	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
DNH82_RS10845	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
DNH82_RS10855	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
DNH82_RS10865	COG1605	Chorismate mutase
DNH82_RS10865	COG0077	Prephenate dehydratase
DNH82_RS10875	COG1335	isochorismatase
DNH82_RS10880	COG1227	inorganic diphosphatase activity
DNH82_RS10890	COG1012	belongs to the aldehyde dehydrogenase family
DNH82_RS10895	COG2706	6-phosphogluconolactonase activity
DNH82_RS10930	COG2610	gluconate transmembrane transporter activity
DNH82_RS10935	COG1070	Carbohydrate kinase
DNH82_RS10950	COG1131	(ABC) transporter
DNH82_RS10970	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
DNH82_RS10975	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DNH82_RS10980	COG1404	Belongs to the peptidase S8 family
DNH82_RS11025	COG4512	PFAM Accessory gene regulator B
DNH82_RS11045	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DNH82_RS11050	COG1621	beta-fructofuranosidase activity
DNH82_RS11055	COG1609	Transcriptional regulator
DNH82_RS11065	COG2124	cytochrome p450
DNH82_RS11075	COG1846	Transcriptional regulator
DNH82_RS11080	COG2814	Major facilitator Superfamily
DNH82_RS11085	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
DNH82_RS11090	COG0488	(ABC) transporter
DNH82_RS11095	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
DNH82_RS11105	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
DNH82_RS11110	COG0456	acetyltransferase
DNH82_RS11115	COG1214	PFAM Peptidase M22, glycoprotease
DNH82_RS11120	COG0802	atpase or kinase
DNH82_RS11125	COG0129	dihydroxy-acid dehydratase activity
DNH82_RS11130	COG0028	Belongs to the TPP enzyme family
DNH82_RS11140	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
DNH82_RS11145	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DNH82_RS11155	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
DNH82_RS11200	COG3091	SprT-like family
DNH82_RS11205	COG2183	response to ionizing radiation
DNH82_RS11210	COG1191	sigma factor activity
DNH82_RS11220	COG1366	Belongs to the anti-sigma-factor antagonist family
DNH82_RS11225	COG2208	phosphoserine phosphatase activity
DNH82_RS11230	COG2337	Toxic component of a toxin-antitoxin (TA) module
DNH82_RS11240	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
DNH82_RS11245	COG0736	holo-[acyl-carrier-protein] synthase activity
DNH82_RS11250	COG3402	PFAM membrane-flanked domain
DNH82_RS11265	COG0513	Belongs to the DEAD box helicase family
DNH82_RS11270	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
DNH82_RS11275	COG1181	Belongs to the D-alanine--D-alanine ligase family
DNH82_RS11280	COG0772	Belongs to the SEDS family
DNH82_RS11300	COG2217	Heavy metal translocating P-type atpase
DNH82_RS11315	COG1937	Protein conserved in bacteria
DNH82_RS11320	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DNH82_RS11325	COG1418	mRNA catabolic process
DNH82_RS11335	COG0706	membrane insertase activity
DNH82_RS11340	COG0352	thiamine-phosphate diphosphorylase activity
DNH82_RS11345	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
DNH82_RS11355	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
DNH82_RS11385	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
DNH82_RS11415	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
DNH82_RS11425	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
DNH82_RS11435	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
DNH82_RS11440	COG0356	it plays a direct role in the translocation of protons across the membrane
DNH82_RS11450	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
DNH82_RS11455	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
DNH82_RS11460	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
DNH82_RS11465	COG4475	Protein of unknown function (DUF436)
DNH82_RS11470	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DNH82_RS11475	COG0009	L-threonylcarbamoyladenylate synthase
DNH82_RS11480	COG2890	protein-(glutamine-N5) methyltransferase activity
DNH82_RS11485	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
DNH82_RS11495	COG0254	rRNA binding
DNH82_RS11500	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
DNH82_RS11510	COG1733	regulation of RNA biosynthetic process
DNH82_RS11515	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
DNH82_RS11520	COG0191	fructose-bisphosphate aldolase activity
DNH82_RS11525	COG4821	SIS domain
DNH82_RS11530	COG2271	Major facilitator Superfamily
DNH82_RS11535	COG0504	CTP synthase activity
DNH82_RS11540	COG3343	RNA polymerase activity
DNH82_RS11545	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DNH82_RS11565	COG5146	pantothenate kinase activity
DNH82_RS11600	COG0813	purine-nucleoside phosphorylase activity
DNH82_RS11610	COG1757	Na H antiporter
DNH82_RS11625	COG1482	cell wall glycoprotein biosynthetic process
DNH82_RS11630	COG2186	Transcriptional regulator
DNH82_RS11640	COG0561	phosphatase activity
DNH82_RS11645	COG1119	ATPase activity
DNH82_RS11655	COG0210	DNA helicase
DNH82_RS11675	COG3711	transcriptional antiterminator
DNH82_RS11690	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DNH82_RS11755	COG0489	protein tyrosine kinase activity
DNH82_RS11760	COG2814	Major facilitator Superfamily
DNH82_RS11780	COG1272	protein, Hemolysin III
DNH82_RS11785	COG4284	Utp--glucose-1-phosphate uridylyltransferase
DNH82_RS11790	COG1988	membrane-bound metal-dependent
DNH82_RS11800	COG3314	Sporulation integral membrane protein YlbJ
DNH82_RS11805	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DNH82_RS11810	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DNH82_RS11815	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
DNH82_RS11820	COG3457	Alanine racemase
DNH82_RS11825	COG4264	IucA IucC family
DNH82_RS11830	COG2814	Major facilitator Superfamily
DNH82_RS11835	COG4264	IucA IucC family
DNH82_RS11840	COG2814	Major facilitator Superfamily
DNH82_RS11845	COG1302	Protein conserved in bacteria
DNH82_RS11860	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
DNH82_RS11870	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DNH82_RS11875	COG0488	(ABC) transporter
DNH82_RS11880	COG2723	6-phospho-beta-galactosidase activity
DNH82_RS11895	COG3684	Belongs to the aldolase LacD family
DNH82_RS11955	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
DNH82_RS11975	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
DNH82_RS11980	COG0101	tRNA pseudouridine synthase activity
DNH82_RS11990	COG1122	ATPase activity
DNH82_RS11995	COG1122	ATPase activity
DNH82_RS12000	COG0203	ribosomal protein L17
DNH82_RS12005	COG0202	RNA polymerase activity
DNH82_RS12010	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
DNH82_RS12020	COG0257	Belongs to the bacterial ribosomal protein bL36 family
DNH82_RS12035	COG0201	protein transport
DNH82_RS12045	COG1841	ribosomal large subunit assembly
DNH82_RS12050	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
DNH82_RS12060	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
DNH82_RS12065	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
DNH82_RS12070	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
DNH82_RS12085	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
DNH82_RS12095	COG0255	Belongs to the universal ribosomal protein uL29 family
DNH82_RS12100	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
DNH82_RS12105	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
DNH82_RS12110	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
DNH82_RS12115	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
DNH82_RS12120	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
DNH82_RS12125	COG0089	rRNA binding
DNH82_RS12130	COG0088	Forms part of the polypeptide exit tunnel
DNH82_RS12135	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
DNH82_RS12155	COG2252	PERMEase
DNH82_RS12185	COG0436	Aminotransferase
DNH82_RS12190	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DNH82_RS12195	COG2348	transferase activity, transferring amino-acyl groups
DNH82_RS12220	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
DNH82_RS12225	COG0746	molybdenum cofactor guanylyltransferase activity
DNH82_RS12235	COG0314	molybdopterin synthase activity
DNH82_RS12255	COG0521	Mo-molybdopterin cofactor biosynthetic process
DNH82_RS12260	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
DNH82_RS12265	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
DNH82_RS12270	COG4149	molybdate abc transporter
DNH82_RS12275	COG0725	ABC transporter, periplasmic molybdate-binding protein
DNH82_RS12280	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
DNH82_RS12285	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
DNH82_RS12290	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
DNH82_RS12295	COG1609	Transcriptional regulator
DNH82_RS12315	COG1268	BioY protein
DNH82_RS12325	COG2186	Transcriptional regulator
DNH82_RS12335	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DNH82_RS12340	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
DNH82_RS12345	COG2832	Protein of unknown function (DUF454)
DNH82_RS12350	COG1960	acyl-CoA dehydrogenase activity
DNH82_RS12370	COG3942	CHAP domain