locus-tag	class	description
DNI27_RS00005	COG2433	Pfam Transposase IS66
DNI27_RS00060	COG4974	Belongs to the 'phage' integrase family
DNI27_RS00065	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
DNI27_RS00070	COG1358	cellular component organization or biogenesis
DNI27_RS00075	COG2740	Nucleic-acid-binding protein implicated in transcription termination
DNI27_RS00080	COG0195	Participates in both transcription termination and antitermination
DNI27_RS00085	COG0779	Required for maturation of 30S ribosomal subunits
DNI27_RS00095	COG0442	prolyl-tRNA aminoacylation
DNI27_RS00105	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
DNI27_RS00110	COG4589	Belongs to the CDS family
DNI27_RS00115	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
DNI27_RS00120	COG0233	cytoplasmic translational termination
DNI27_RS00125	COG0528	UMP kinase activity
DNI27_RS00130	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
DNI27_RS00135	COG0052	Belongs to the universal ribosomal protein uS2 family
DNI27_RS00140	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
DNI27_RS00145	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
DNI27_RS00150	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
DNI27_RS00155	COG4974	Belongs to the 'phage' integrase family
DNI27_RS00160	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
DNI27_RS00165	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
DNI27_RS00170	COG0758	DNA mediated transformation
DNI27_RS00180	COG0045	succinate-CoA ligase (ADP-forming) activity
DNI27_RS00190	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
DNI27_RS00205	COG4485	Bacterial membrane protein, YfhO
DNI27_RS00245	COG0336	Belongs to the RNA methyltransferase TrmD family
DNI27_RS00250	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
DNI27_RS00255	COG0228	four-way junction DNA binding
DNI27_RS00310	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
DNI27_RS00315	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
DNI27_RS00320	COG0552	protein localization to endoplasmic reticulum
DNI27_RS00325	COG1196	nuclear chromosome segregation
DNI27_RS00330	COG0571	ribonuclease III activity
DNI27_RS00335	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DNI27_RS00350	COG0416	fatty acid biosynthetic process
DNI27_RS00355	COG1349	DNA-binding transcription factor activity
DNI27_RS00365	COG1760	l-serine dehydratase
DNI27_RS00370	COG1760	l-serine dehydratase
DNI27_RS00380	COG1302	Protein conserved in bacteria
DNI27_RS00395	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
DNI27_RS00400	COG1162	GTPase activity
DNI27_RS00410	COG2124	cytochrome p450
DNI27_RS00425	COG0820	rRNA (adenine-C2-)-methyltransferase activity
DNI27_RS00430	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
DNI27_RS00430	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
DNI27_RS00435	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
DNI27_RS00440	COG0242	peptide deformylase activity
DNI27_RS00445	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
DNI27_RS00450	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
DNI27_RS00465	COG1758	RNA polymerase activity
DNI27_RS00485	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
DNI27_RS00490	COG0284	orotidine-5'-phosphate decarboxylase activity
DNI27_RS00495	COG0167	dihydroorotate dehydrogenase activity
DNI27_RS00505	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
DNI27_RS00510	COG0505	Belongs to the CarA family
DNI27_RS00530	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
DNI27_RS00535	COG0564	pseudouridine synthase activity
DNI27_RS00540	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
DNI27_RS00545	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
DNI27_RS00550	COG3599	regulation of cell shape
DNI27_RS00560	COG0673	inositol 2-dehydrogenase activity
DNI27_RS00565	COG4409	exo-alpha-(2->6)-sialidase activity
DNI27_RS00575	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DNI27_RS00580	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DNI27_RS00590	COG4975	Glucose uptake
DNI27_RS00595	COG1869	D-ribose catabolic process
DNI27_RS00600	COG0762	integral membrane protein
DNI27_RS00605	COG1799	cell septum assembly
DNI27_RS00610	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
DNI27_RS00620	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
DNI27_RS00625	COG0849	cell division
DNI27_RS00635	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
DNI27_RS00645	COG0768	penicillin binding
DNI27_RS00650	COG4839	cell division protein FtsL
DNI27_RS00655	COG0275	rRNA processing
DNI27_RS00660	COG2001	Belongs to the MraZ family
DNI27_RS00665	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
DNI27_RS00670	COG0454	-acetyltransferase
DNI27_RS00675	COG1011	Hydrolase
DNI27_RS00690	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
DNI27_RS00750	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
DNI27_RS00755	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
DNI27_RS00760	COG1053	succinate dehydrogenase
DNI27_RS00765	COG2009	succinate dehydrogenase
DNI27_RS00770	COG0322	excinuclease ABC activity
DNI27_RS00775	COG3118	belongs to the thioredoxin family
DNI27_RS00780	COG1193	negative regulation of DNA recombination
DNI27_RS00785	COG1796	DNA polymerase
DNI27_RS00785	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
DNI27_RS00800	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
DNI27_RS00815	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
DNI27_RS00820	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DNI27_RS00825	COG0333	Belongs to the bacterial ribosomal protein bL32 family
DNI27_RS00845	COG0742	ribosomal rna small subunit methyltransferase
DNI27_RS00855	COG4471	UPF0298 protein
DNI27_RS00860	COG0584	glycerophosphoryl diester phosphodiesterase
DNI27_RS00865	COG3679	Belongs to the UPF0342 family
DNI27_RS00890	COG0109	protoheme IX farnesyltransferase activity
DNI27_RS00915	COG0772	Belongs to the SEDS family
DNI27_RS00920	COG4838	Belongs to the UPF0358 family
DNI27_RS00925	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
DNI27_RS00930	COG4896	Protein conserved in bacteria
DNI27_RS00935	COG1902	pentaerythritol trinitrate reductase activity
DNI27_RS00940	COG1217	gtp-binding protein TYPA
DNI27_RS00950	COG0483	inositol monophosphate 1-phosphatase activity
DNI27_RS00955	COG4493	Belongs to the UPF0637 family
DNI27_RS00970	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
DNI27_RS00975	COG1177	transmembrane transport
DNI27_RS00985	COG3842	ATPase activity
DNI27_RS00995	COG4476	Belongs to the UPF0223 family
DNI27_RS01035	COG5503	Protein of unknown function (DUF1447)
DNI27_RS01040	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
DNI27_RS01050	COG0492	ferredoxin-NADP+ reductase activity
DNI27_RS01075	COG0569	domain protein
DNI27_RS01080	COG1294	oxidase, subunit
DNI27_RS01085	COG1271	oxidase subunit
DNI27_RS01090	COG1393	Belongs to the ArsC family
DNI27_RS01095	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DNI27_RS01100	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
DNI27_RS01110	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
DNI27_RS01125	COG4172	Belongs to the ABC transporter superfamily
DNI27_RS01135	COG0151	Belongs to the GarS family
DNI27_RS01140	COG0138	bifunctional purine biosynthesis protein purh
DNI27_RS01150	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
DNI27_RS01155	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
DNI27_RS01165	COG0047	phosphoribosylformylglycinamidine synthase activity
DNI27_RS01170	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
DNI27_RS01175	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
DNI27_RS01180	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
DNI27_RS01185	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
DNI27_RS01190	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
DNI27_RS01195	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
DNI27_RS01195	COG1017	nitric oxide dioxygenase activity
DNI27_RS01205	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
DNI27_RS01215	COG1845	cytochrome c oxidase, subunit III
DNI27_RS01220	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
DNI27_RS01230	COG3973	AAA domain
DNI27_RS01270	COG3212	peptidase
DNI27_RS01285	COG1134	teichoic acid transport
DNI27_RS01295	COG1682	transport, permease protein
DNI27_RS01305	COG1215	transferase activity, transferring glycosyl groups
DNI27_RS01315	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
DNI27_RS01320	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DNI27_RS01325	COG1316	TRANSCRIPTIONal
DNI27_RS01350	COG3594	Acyltransferase
DNI27_RS01355	COG0436	Aminotransferase
DNI27_RS01360	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
DNI27_RS01370	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
DNI27_RS01375	COG1169	isochorismate synthase
DNI27_RS01380	COG1575	Belongs to the MenA family. Type 1 subfamily
DNI27_RS01385	COG0390	transport system, permease component
DNI27_RS01390	COG4619	ABC transporter
DNI27_RS01410	COG4873	Protein conserved in bacteria
DNI27_RS01490	COG2378	regulation of single-species biofilm formation
DNI27_RS01500	COG0456	acetyltransferase
DNI27_RS01510	COG2226	methyltransferase
DNI27_RS01550	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
DNI27_RS01550	COG0551	DNA topoisomerase type I activity
DNI27_RS01595	COG0737	Belongs to the 5'-nucleotidase family
DNI27_RS01605	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DNI27_RS01610	COG1696	Membrane protein involved in D-alanine export
DNI27_RS01620	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
DNI27_RS01625	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
DNI27_RS01630	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DNI27_RS01635	COG0861	Integral membrane protein TerC family
DNI27_RS01640	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
DNI27_RS01650	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
DNI27_RS01655	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
DNI27_RS01660	COG2814	Major facilitator Superfamily
DNI27_RS01670	COG3715	PTS system
DNI27_RS01675	COG3716	PTS system mannose fructose sorbose family IID component
DNI27_RS01680	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
DNI27_RS01685	COG2382	esterase
DNI27_RS01690	COG1115	amino acid carrier protein
DNI27_RS01695	COG0628	permease
DNI27_RS01705	COG0569	domain protein
DNI27_RS01705	COG0475	glutathione-regulated potassium exporter activity
DNI27_RS01710	COG2239	Acts as a magnesium transporter
DNI27_RS01715	COG0564	pseudouridine synthase activity
DNI27_RS01725	COG2357	RelA SpoT domain protein
DNI27_RS01740	COG2346	COG2346, Truncated hemoglobins
DNI27_RS01745	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
DNI27_RS01755	COG1164	Oligoendopeptidase f
DNI27_RS01770	COG3591	Belongs to the peptidase S1B family
DNI27_RS01780	COG1393	Belongs to the ArsC family
DNI27_RS01785	COG0180	Tryptophanyl-tRNA synthetase
DNI27_RS01790	COG4166	transmembrane transport
DNI27_RS01795	COG4608	Belongs to the ABC transporter superfamily
DNI27_RS01800	COG0444	Belongs to the ABC transporter superfamily
DNI27_RS01805	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DNI27_RS01810	COG0601	transmembrane transport
DNI27_RS01840	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
DNI27_RS01860	COG0561	phosphatase activity
DNI27_RS01865	COG0446	pyridine nucleotide-disulphide oxidoreductase
DNI27_RS01880	COG0179	Fumarylacetoacetate (FAA) hydrolase
DNI27_RS01890	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
DNI27_RS01905	COG0166	Belongs to the GPI family
DNI27_RS01910	COG0137	argininosuccinate synthase activity
DNI27_RS01920	COG0584	glycerophosphoryl diester phosphodiesterase
DNI27_RS01935	COG1012	belongs to the aldehyde dehydrogenase family
DNI27_RS01940	COG1098	S1 RNA binding domain
DNI27_RS01950	COG1278	Cold shock
DNI27_RS01970	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
DNI27_RS01980	COG2111	Na H antiporter
DNI27_RS01980	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
DNI27_RS01985	COG2111	Na H antiporter
DNI27_RS01990	COG1006	Multisubunit Na H antiporter MnhC subunit
DNI27_RS01995	COG0651	ATP synthesis coupled electron transport
DNI27_RS02000	COG1863	multisubunit Na H antiporter MnhE subunit
DNI27_RS02005	COG2212	antiporter activity
DNI27_RS02010	COG1320	monovalent cation:proton antiporter activity
DNI27_RS02020	COG2056	Na+-H+ antiporter family
DNI27_RS02025	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
DNI27_RS02030	COG1252	NADH dehydrogenase
DNI27_RS02035	COG0316	Belongs to the HesB IscA family
DNI27_RS02040	COG4844	belongs to the
DNI27_RS02045	COG1252	NADH dehydrogenase
DNI27_RS02050	COG4837	Protein of unknown function (DUF1462)
DNI27_RS02055	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
DNI27_RS02060	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DNI27_RS02065	COG0647	UMP catabolic process
DNI27_RS02070	COG2445	Protein of unknown function DUF86
DNI27_RS02080	COG4470	Protein conserved in bacteria
DNI27_RS02085	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
DNI27_RS02090	COG0737	Belongs to the 5'-nucleotidase family
DNI27_RS02095	COG0730	response to heat
DNI27_RS02100	COG1801	Protein of unknown function DUF72
DNI27_RS02115	COG1253	flavin adenine dinucleotide binding
DNI27_RS02125	COG0719	Fe-S assembly protein
DNI27_RS02130	COG0822	iron-sulfur transferase activity
DNI27_RS02140	COG0719	Fe-S assembly protein
DNI27_RS02145	COG0396	ATPase activity
DNI27_RS02155	COG1464	Belongs to the NlpA lipoprotein family
DNI27_RS02160	COG1464	Belongs to the NlpA lipoprotein family
DNI27_RS02165	COG2011	ABC-type metal ion transport system permease component
DNI27_RS02170	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
DNI27_RS02175	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DNI27_RS02180	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
DNI27_RS02190	COG1393	Belongs to the ArsC family
DNI27_RS02195	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DNI27_RS02205	COG0710	3-dehydroquinate dehydratase activity
DNI27_RS02215	COG1764	response to oxidative stress
DNI27_RS02230	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
DNI27_RS02250	COG0346	lactoylglutathione lyase activity
DNI27_RS02280	COG0557	exoribonuclease II activity
DNI27_RS02285	COG1647	Serine aminopeptidase, S33
DNI27_RS02290	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
DNI27_RS02315	COG0148	phosphopyruvate hydratase activity
DNI27_RS02320	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
DNI27_RS02350	COG1090	epimerase
DNI27_RS02360	COG0740	serine-type endopeptidase activity
DNI27_RS02370	COG1481	regulation of sporulation
DNI27_RS02375	COG0391	Required for morphogenesis under gluconeogenic growth conditions
DNI27_RS02380	COG1660	Displays ATPase and GTPase activities
DNI27_RS02395	COG0110	maltose O-acetyltransferase activity
DNI27_RS02400	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
DNI27_RS02405	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
DNI27_RS02440	COG0653	protein targeting
DNI27_RS02455	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
DNI27_RS02465	COG1739	Uncharacterized protein family UPF0029
DNI27_RS02470	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DNI27_RS02490	COG2195	Cleaves the N-terminal amino acid of tripeptides
DNI27_RS02495	COG1929	Belongs to the glycerate kinase type-1 family
DNI27_RS02500	COG3118	belongs to the thioredoxin family
DNI27_RS02515	COG0812	UDP-N-acetylmuramate dehydrogenase activity
DNI27_RS02525	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DNI27_RS02530	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DNI27_RS02565	COG3104	oligopeptide transport
DNI27_RS02570	COG3104	oligopeptide transport
DNI27_RS02585	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
DNI27_RS02590	COG1174	glycine betaine transport
DNI27_RS02595	COG1125	glycine betaine transport
DNI27_RS02595	COG0517	IMP dehydrogenase activity
DNI27_RS02600	COG0514	ATP-dependent DNA helicase (RecQ)
DNI27_RS02605	COG0488	(ABC) transporter
DNI27_RS02615	COG2274	protein secretion by the type I secretion system
DNI27_RS02630	COG0463	Glycosyl transferase, family 2
DNI27_RS02635	COG1368	sulfuric ester hydrolase activity
DNI27_RS02645	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
DNI27_RS02665	COG0512	Glutamine amidotransferase of anthranilate synthase
DNI27_RS02675	COG0720	synthase
DNI27_RS02680	COG0602	queuosine metabolic process
DNI27_RS02695	COG0463	Glycosyl transferase, family 2
DNI27_RS02700	COG1253	flavin adenine dinucleotide binding
DNI27_RS02705	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DNI27_RS02705	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DNI27_RS02705	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DNI27_RS02710	COG1105	Belongs to the carbohydrate kinase PfkB family
DNI27_RS02715	COG1349	DNA-binding transcription factor activity
DNI27_RS02730	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
DNI27_RS02735	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
DNI27_RS02755	COG0039	L-malate dehydrogenase activity
DNI27_RS02770	COG4989	oxidoreductase activity
DNI27_RS02775	COG0523	cobalamin synthesis protein
DNI27_RS02785	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
DNI27_RS02790	COG4988	ABC transporter
DNI27_RS02795	COG1968	undecaprenyl-diphosphatase activity
DNI27_RS02805	COG1671	Belongs to the UPF0178 family
DNI27_RS02810	COG1611	Belongs to the LOG family
DNI27_RS02840	COG2839	Protein conserved in bacteria
DNI27_RS02845	COG2814	Major facilitator Superfamily
DNI27_RS02850	COG0583	DNA-binding transcription factor activity
DNI27_RS02865	COG0217	transcriptional regulatory protein
DNI27_RS02870	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
DNI27_RS02875	COG2022	thiamine diphosphate biosynthetic process
DNI27_RS02885	COG0352	thiamine-phosphate diphosphorylase activity
DNI27_RS02895	COG1388	LysM domain
DNI27_RS02895	COG3942	CHAP domain
DNI27_RS02900	COG0306	phosphate transporter
DNI27_RS02905	COG1392	Phosphate transport regulator
DNI27_RS02910	COG0577	efflux transmembrane transporter activity
DNI27_RS02915	COG1136	(ABC) transporter
DNI27_RS02925	COG0745	RESPONSE REGULATOR receiver
DNI27_RS02930	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DNI27_RS02935	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DNI27_RS02945	COG3949	Membrane
DNI27_RS02950	COG0477	Major facilitator Superfamily
DNI27_RS02960	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DNI27_RS02965	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DNI27_RS02970	COG1120	ATPase activity
DNI27_RS02975	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DNI27_RS02980	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
DNI27_RS03000	COG1132	(ABC) transporter
DNI27_RS03005	COG1686	Belongs to the peptidase S11 family
DNI27_RS03025	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
DNI27_RS03030	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
DNI27_RS03035	COG1682	transport, permease protein
DNI27_RS03045	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
DNI27_RS03050	COG0110	maltose O-acetyltransferase activity
DNI27_RS03060	COG1475	DNA binding
DNI27_RS03065	COG0019	diaminopimelate decarboxylase activity
DNI27_RS03075	COG4264	IucA IucC family
DNI27_RS03080	COG4264	IucA IucC family
DNI27_RS03085	COG2814	Major facilitator Superfamily
DNI27_RS03090	COG4264	IucA IucC family
DNI27_RS03095	COG2423	ornithine cyclodeaminase activity
DNI27_RS03105	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
DNI27_RS03110	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DNI27_RS03115	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DNI27_RS03125	COG1121	(ABC) transporter
DNI27_RS03130	COG1108	ABC-type Mn2 Zn2 transport systems permease components
DNI27_RS03135	COG0803	Belongs to the bacterial solute-binding protein 9 family
DNI27_RS03140	COG1320	monovalent cation:proton antiporter activity
DNI27_RS03145	COG2212	antiporter activity
DNI27_RS03150	COG1863	multisubunit Na H antiporter MnhE subunit
DNI27_RS03160	COG1006	Multisubunit Na H antiporter MnhC subunit
DNI27_RS03165	COG2111	Na H antiporter
DNI27_RS03170	COG2111	Na H antiporter
DNI27_RS03170	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
DNI27_RS03220	COG0546	phosphoglycolate phosphatase activity
DNI27_RS03225	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DNI27_RS03230	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
DNI27_RS03235	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
DNI27_RS03240	COG0805	protein transport
DNI27_RS03245	COG0018	arginyl-trna synthetase
DNI27_RS03260	COG1078	dGTPase activity
DNI27_RS03270	COG4844	belongs to the
DNI27_RS03330	COG0471	metal ion transport
DNI27_RS03360	COG0280	phosphate acetyltransferase
DNI27_RS03365	COG0095	Lipoate-protein ligase
DNI27_RS03370	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DNI27_RS03375	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
DNI27_RS03385	COG2814	Major facilitator Superfamily
DNI27_RS03390	COG1566	PFAM secretion protein HlyD family protein
DNI27_RS03400	COG2311	Membrane
DNI27_RS03435	COG2363	Small membrane protein
DNI27_RS03465	COG0183	Belongs to the thiolase family
DNI27_RS03470	COG0318	PFAM AMP-dependent synthetase and ligase
DNI27_RS03475	COG0588	phosphoglycerate mutase activity
DNI27_RS03480	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
DNI27_RS03485	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
DNI27_RS03495	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
DNI27_RS03510	COG2190	(PTS) system
DNI27_RS03510	COG1263	PTS System
DNI27_RS03510	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DNI27_RS03525	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
DNI27_RS03530	COG1469	GTP cyclohydrolase I activity
DNI27_RS03580	COG0577	efflux transmembrane transporter activity
DNI27_RS03580	COG1136	(ABC) transporter
DNI27_RS03595	COG0561	phosphatase activity
DNI27_RS03605	COG1428	Deoxynucleoside kinase
DNI27_RS03610	COG1428	Deoxynucleoside kinase
DNI27_RS03615	COG0546	phosphoglycolate phosphatase activity
DNI27_RS03645	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DNI27_RS03655	COG1473	amidohydrolase
DNI27_RS03660	COG3527	Alpha-acetolactate decarboxylase
DNI27_RS03665	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
DNI27_RS03670	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
DNI27_RS03675	COG0049	tRNA binding
DNI27_RS03680	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
DNI27_RS03690	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
DNI27_RS03695	COG0085	RNA polymerase activity
DNI27_RS03700	COG2813	Specifically methylates the guanine in position
DNI27_RS03710	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
DNI27_RS03715	COG0081	regulation of translation
DNI27_RS03720	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
DNI27_RS03725	COG0250	Participates in transcription elongation, termination and antitermination
DNI27_RS03730	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
DNI27_RS03735	COG0267	Belongs to the bacterial ribosomal protein bL33 family
DNI27_RS03755	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
DNI27_RS03760	COG0215	cysteine-tRNA ligase activity
DNI27_RS03765	COG1045	serine acetyltransferase
DNI27_RS03770	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DNI27_RS03780	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
DNI27_RS03785	COG4956	integral membrane protein (PIN domain superfamily)
DNI27_RS03790	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
DNI27_RS03825	COG0542	response to heat
DNI27_RS03830	COG3869	Catalyzes the specific phosphorylation of arginine residues in
DNI27_RS03835	COG3880	PFAM UvrB UvrC protein
DNI27_RS03845	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
DNI27_RS03855	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
DNI27_RS03860	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
DNI27_RS03865	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DNI27_RS03870	COG1289	transmembrane transporter activity
DNI27_RS03960	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
DNI27_RS03965	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
DNI27_RS03975	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
DNI27_RS03985	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
DNI27_RS03990	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DNI27_RS04005	COG1098	S1 RNA binding domain
DNI27_RS04015	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
DNI27_RS04020	COG3956	TIGRFAM MazG family protein
DNI27_RS04025	COG2244	polysaccharide biosynthetic process
DNI27_RS04030	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
DNI27_RS04035	COG0193	aminoacyl-tRNA hydrolase activity
DNI27_RS04045	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
DNI27_RS04050	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
DNI27_RS04055	COG2088	sporulation resulting in formation of a cellular spore
DNI27_RS04060	COG0251	oxidation-reduction process
DNI27_RS04065	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
DNI27_RS04070	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
DNI27_RS04075	COG4466	Protein conserved in bacteria
DNI27_RS04085	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
DNI27_RS04090	COG0084	hydrolase, TatD family'
DNI27_RS04100	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
DNI27_RS04105	COG2827	Endonuclease containing a URI domain
DNI27_RS04110	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
DNI27_RS04115	COG4467	Involved in initiation control of chromosome replication
DNI27_RS04120	COG1774	PSP1 C-terminal conserved region
DNI27_RS04125	COG0470	DNA polymerase III
DNI27_RS04130	COG3870	Protein conserved in bacteria
DNI27_RS04135	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
DNI27_RS04140	COG1982	Orn Lys Arg decarboxylase major
DNI27_RS04165	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
DNI27_RS04170	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
DNI27_RS04175	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
DNI27_RS04180	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
DNI27_RS04190	COG2188	Transcriptional regulator
DNI27_RS04195	COG0366	Alpha amylase catalytic
DNI27_RS04200	COG1263	PTS System
DNI27_RS04200	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DNI27_RS04215	COG0070	glutamate synthase
DNI27_RS04215	COG0067	glutamate synthase
DNI27_RS04215	COG0069	glutamate synthase activity
DNI27_RS04220	COG0583	DNA-binding transcription factor activity
DNI27_RS04235	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
DNI27_RS04250	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DNI27_RS04270	COG1131	(ABC) transporter
DNI27_RS04315	COG0626	cystathionine gamma-synthase activity
DNI27_RS04320	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
DNI27_RS04325	COG2272	Belongs to the type-B carboxylesterase lipase family
DNI27_RS04330	COG0733	neurotransmitter:sodium symporter activity
DNI27_RS04340	COG0745	RESPONSE REGULATOR receiver
DNI27_RS04345	COG2205	protein histidine kinase activity
DNI27_RS04355	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
DNI27_RS04360	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
DNI27_RS04375	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
DNI27_RS04380	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DNI27_RS04380	COG0574	Belongs to the PEP-utilizing enzyme family
DNI27_RS04410	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
DNI27_RS04420	COG1486	melibiose metabolic process
DNI27_RS04425	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DNI27_RS04425	COG1263	PTS System
DNI27_RS04445	COG2210	Belongs to the sulfur carrier protein TusA family
DNI27_RS04450	COG1937	Protein conserved in bacteria
DNI27_RS04455	COG0730	response to heat
DNI27_RS04460	COG2814	Major facilitator Superfamily
DNI27_RS04480	COG3682	Transcriptional regulator
DNI27_RS04505	COG1124	(ABC) transporter
DNI27_RS04510	COG0444	Belongs to the ABC transporter superfamily
DNI27_RS04515	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DNI27_RS04520	COG0601	transmembrane transport
DNI27_RS04525	COG0747	negative chemotaxis
DNI27_RS04550	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
DNI27_RS04570	COG1525	nuclease
DNI27_RS04590	COG0519	Catalyzes the synthesis of GMP from XMP
DNI27_RS04590	COG0518	GMP synthase (glutamine-hydrolyzing) activity
DNI27_RS04595	COG0516	GMP reductase activity
DNI27_RS04595	COG0517	IMP dehydrogenase activity
DNI27_RS04600	COG2233	PERMEase
DNI27_RS04605	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
DNI27_RS04620	COG5183	chlorophyll binding
DNI27_RS04625	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DNI27_RS04630	COG1823	symporter activity
DNI27_RS04655	COG0778	Nitroreductase
DNI27_RS04660	COG0450	alkyl hydroperoxide reductase
DNI27_RS04675	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
DNI27_RS04685	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
DNI27_RS04690	COG2011	ABC-type metal ion transport system permease component
DNI27_RS04695	COG1464	Belongs to the NlpA lipoprotein family
DNI27_RS04700	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
DNI27_RS04705	COG0753	catalase activity
DNI27_RS04710	COG3842	ATPase activity
DNI27_RS04715	COG0673	inositol 2-dehydrogenase activity
DNI27_RS04720	COG0395	ABC-type sugar transport system, permease component
DNI27_RS04725	COG1175	transmembrane transport
DNI27_RS04735	COG2207	Transcriptional regulator
DNI27_RS04735	COG0662	Cupin 2, conserved barrel domain protein
DNI27_RS04740	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
DNI27_RS04750	COG0360	Binds together with S18 to 16S ribosomal RNA
DNI27_RS04760	COG1668	transmembrane transport
DNI27_RS04765	COG1131	(ABC) transporter
DNI27_RS04770	COG0012	GTP binding
DNI27_RS04775	COG4481	Protein conserved in bacteria
DNI27_RS04780	COG0668	transmembrane transport
DNI27_RS04785	COG1475	DNA binding
DNI27_RS04790	COG0626	cystathionine gamma-synthase activity
DNI27_RS04795	COG0626	cystathionine gamma-synthase activity
DNI27_RS04800	COG0646	methionine synthase
DNI27_RS04800	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
DNI27_RS04810	COG0829	nickel cation binding
DNI27_RS04820	COG0830	nickel cation binding
DNI27_RS04825	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
DNI27_RS04835	COG2388	GCN5-related N-acetyl-transferase
DNI27_RS04840	COG1846	Transcriptional regulator
DNI27_RS04845	COG0346	lactoylglutathione lyase activity
DNI27_RS04850	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
DNI27_RS04855	COG0400	carboxylic ester hydrolase activity
DNI27_RS04880	COG0357	Ribosomal RNA small subunit methyltransferase G
DNI27_RS04885	COG0445	tRNA wobble uridine modification
DNI27_RS04890	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
DNI27_RS04895	COG0594	ribonuclease P activity
DNI27_RS04905	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
DNI27_RS04910	COG0592	DNA-directed DNA polymerase activity
DNI27_RS04915	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
DNI27_RS04915	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
DNI27_RS04920	COG2501	S4 domain
DNI27_RS04925	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
DNI27_RS04930	COG0187	DNA topoisomerase II activity
DNI27_RS04940	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
DNI27_RS04945	COG2986	histidine ammonia-lyase
DNI27_RS04955	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
DNI27_RS04965	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
DNI27_RS04970	COG4241	membrane
DNI27_RS04975	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
DNI27_RS04980	COG0359	binds to the 23S rRNA
DNI27_RS04985	COG0305	Participates in initiation and elongation during chromosome replication
DNI27_RS04990	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
DNI27_RS04995	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DNI27_RS05015	COG0745	RESPONSE REGULATOR receiver
DNI27_RS05020	COG5002	protein histidine kinase activity
DNI27_RS05025	COG4863	YycH protein
DNI27_RS05035	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
DNI27_RS05055	COG0584	glycerophosphoryl diester phosphodiesterase
DNI27_RS05060	COG2030	dehydratase
DNI27_RS05085	COG1940	carbohydrate kinase activity
DNI27_RS05085	COG1846	Transcriptional regulator
DNI27_RS05095	COG2210	Belongs to the sulfur carrier protein TusA family
DNI27_RS05100	COG1937	Protein conserved in bacteria
DNI27_RS05105	COG0730	response to heat
DNI27_RS05140	COG2003	Belongs to the UPF0758 family
DNI27_RS05220	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
DNI27_RS05255	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
DNI27_RS05300	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
DNI27_RS05320	COG0640	Transcriptional regulator
DNI27_RS05325	COG2217	Heavy metal translocating P-type atpase
DNI27_RS05350	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
DNI27_RS05365	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
DNI27_RS05375	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
DNI27_RS05415	COG0531	amino acid
DNI27_RS05420	COG2217	Heavy metal translocating P-type atpase
DNI27_RS05435	COG3655	Transcriptional regulator
DNI27_RS05450	COG2188	Transcriptional regulator
DNI27_RS05455	COG2723	6-phospho-beta-galactosidase activity
DNI27_RS05465	COG0415	Belongs to the DNA photolyase family
DNI27_RS05480	COG0702	epimerase
DNI27_RS05485	COG2130	NADP-dependent
DNI27_RS05495	COG3655	Transcriptional regulator
DNI27_RS05500	COG3177	Filamentation induced by cAMP protein fic
DNI27_RS05505	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DNI27_RS05510	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DNI27_RS05510	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DNI27_RS05515	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
DNI27_RS05520	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DNI27_RS05540	COG2235	arginine
DNI27_RS05555	COG2197	response regulator
DNI27_RS05560	COG2203	Gaf domain
DNI27_RS05560	COG4585	Histidine kinase
DNI27_RS05565	COG0842	Transport permease protein
DNI27_RS05570	COG1131	(ABC) transporter
DNI27_RS05590	COG0431	NADPH-dependent FMN reductase
DNI27_RS05595	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
DNI27_RS05595	COG3583	domain protein
DNI27_RS05595	COG4932	domain protein
DNI27_RS05615	COG1609	Transcriptional regulator
DNI27_RS05625	COG0673	inositol 2-dehydrogenase activity
DNI27_RS05635	COG0366	Alpha amylase catalytic
DNI27_RS05645	COG3833	ABC-type maltose transport systems, permease component
DNI27_RS05650	COG1175	transmembrane transport
DNI27_RS05660	COG3842	ATPase activity
DNI27_RS05665	COG0475	glutathione-regulated potassium exporter activity
DNI27_RS05670	COG0490	domain, Protein
DNI27_RS05680	COG0346	lactoylglutathione lyase activity
DNI27_RS05715	COG1131	(ABC) transporter
DNI27_RS05725	COG0366	Alpha amylase catalytic
DNI27_RS05730	COG2188	Transcriptional regulator
DNI27_RS05735	COG2222	sugar isomerase
DNI27_RS05740	COG1105	Belongs to the carbohydrate kinase PfkB family
DNI27_RS05755	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DNI27_RS05755	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
DNI27_RS05760	COG3715	PTS system
DNI27_RS05765	COG3716	PTS system mannose fructose sorbose family IID component
DNI27_RS05775	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
DNI27_RS05795	COG3314	Sporulation integral membrane protein YlbJ
DNI27_RS05815	COG1063	alcohol dehydrogenase
DNI27_RS05830	COG1620	l-lactate permease
DNI27_RS05835	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
DNI27_RS05840	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
DNI27_RS05845	COG0156	8-amino-7-oxononanoate synthase activity
DNI27_RS05890	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
DNI27_RS05905	COG0076	glutamate decarboxylase activity
DNI27_RS05920	COG2318	DinB family
DNI27_RS05925	COG0753	catalase activity
DNI27_RS05935	COG0783	Belongs to the Dps family
DNI27_RS05945	COG0436	Aminotransferase
DNI27_RS05970	COG1136	(ABC) transporter
DNI27_RS05980	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DNI27_RS06000	COG1755	Isoprenylcysteine carboxyl methyltransferase
DNI27_RS06025	COG0579	oxidoreductase
DNI27_RS06060	COG1073	alpha beta
DNI27_RS06080	COG0438	transferase activity, transferring glycosyl groups
DNI27_RS06085	COG0183	Belongs to the thiolase family
DNI27_RS06095	COG1960	acyl-CoA dehydrogenase activity
DNI27_RS06100	COG0318	PFAM AMP-dependent synthetase and ligase
DNI27_RS06110	COG2814	Major facilitator Superfamily
DNI27_RS06120	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DNI27_RS06130	COG1116	anion transmembrane transporter activity
DNI27_RS06150	COG1609	Transcriptional regulator
DNI27_RS06155	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DNI27_RS06180	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
DNI27_RS06220	COG3711	transcriptional antiterminator
DNI27_RS06225	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DNI27_RS06235	COG3037	sugar-specific permease SgaT UlaA
DNI27_RS06245	COG1328	CTP reductase activity
DNI27_RS06265	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DNI27_RS06270	COG1942	4-Oxalocrotonate Tautomerase
DNI27_RS06280	COG3443	Belongs to the bacterial solute-binding protein 9 family
DNI27_RS06280	COG0803	Belongs to the bacterial solute-binding protein 9 family
DNI27_RS06305	COG2207	Transcriptional regulator
DNI27_RS06305	COG4753	response regulator
DNI27_RS06310	COG2972	Histidine kinase
DNI27_RS06320	COG1210	Utp--glucose-1-phosphate uridylyltransferase
DNI27_RS06325	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
DNI27_RS06330	COG0477	Major facilitator Superfamily
DNI27_RS06335	COG2211	Major facilitator Superfamily
DNI27_RS06340	COG3250	beta-galactosidase activity
DNI27_RS06345	COG1957	nucleoside hydrolase
DNI27_RS06380	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
DNI27_RS06385	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
DNI27_RS06390	COG2807	transmembrane transport
DNI27_RS06395	COG1396	sequence-specific DNA binding
DNI27_RS06410	COG1785	Belongs to the alkaline phosphatase family
DNI27_RS06435	COG1510	regulation of RNA biosynthetic process
DNI27_RS06440	COG1012	belongs to the aldehyde dehydrogenase family
DNI27_RS06445	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
DNI27_RS06450	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
DNI27_RS06460	COG0156	8-amino-7-oxononanoate synthase activity
DNI27_RS06475	COG0107	imidazoleglycerol-phosphate synthase activity
DNI27_RS06480	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
DNI27_RS06495	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
DNI27_RS06500	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
DNI27_RS06505	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
DNI27_RS06510	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
DNI27_RS06545	COG2376	Dihydroxyacetone kinase
DNI27_RS06550	COG1461	Dihydroxyacetone kinase
DNI27_RS06555	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
DNI27_RS06560	COG2824	Alkylphosphonate utilization operon protein PhnA
DNI27_RS06565	COG1012	belongs to the aldehyde dehydrogenase family
DNI27_RS06580	COG0596	Alpha beta hydrolase
DNI27_RS06585	COG0789	Transcriptional regulator
DNI27_RS06590	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DNI27_RS06590	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DNI27_RS06590	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DNI27_RS06600	COG1705	Flagellar rod assembly protein muramidase FlgJ
DNI27_RS06600	COG3942	CHAP domain
DNI27_RS06610	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
DNI27_RS06615	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
DNI27_RS06620	COG0747	negative chemotaxis
DNI27_RS06645	COG0463	Glycosyl transferase, family 2
DNI27_RS06645	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
DNI27_RS06650	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
DNI27_RS06650	COG0463	Glycosyl transferase, family 2
DNI27_RS06655	COG0438	transferase activity, transferring glycosyl groups
DNI27_RS06660	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DNI27_RS06665	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
DNI27_RS06680	COG3181	Tripartite tricarboxylate transporter family receptor
DNI27_RS06685	COG0778	Nitroreductase
DNI27_RS06690	COG3001	Fructosamine kinase
DNI27_RS06715	COG1136	(ABC) transporter
DNI27_RS06720	COG0577	efflux transmembrane transporter activity
DNI27_RS06740	COG4413	Urea transporter
DNI27_RS06750	COG0832	Belongs to the urease beta subunit family
DNI27_RS06755	COG0804	urea catabolic process
DNI27_RS06760	COG0717	Belongs to the dCTP deaminase family
DNI27_RS06765	COG0523	cobalamin synthesis protein
DNI27_RS06775	COG1141	Ferredoxin
DNI27_RS06800	COG0583	DNA-binding transcription factor activity
DNI27_RS06810	COG1346	cytolysis
DNI27_RS06825	COG1846	Transcriptional regulator
DNI27_RS06830	COG0778	Nitroreductase
DNI27_RS06835	COG2357	RelA SpoT domain protein
DNI27_RS06875	COG1028	Short-chain dehydrogenase reductase Sdr
DNI27_RS06890	COG3835	regulator
DNI27_RS06895	COG2855	membrane
DNI27_RS06900	COG3961	Belongs to the TPP enzyme family
DNI27_RS06905	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
DNI27_RS06910	COG0512	Glutamine amidotransferase of anthranilate synthase
DNI27_RS06920	COG0134	indole-3-glycerol-phosphate synthase activity
DNI27_RS06930	COG0133	tryptophan synthase activity
DNI27_RS06935	COG0159	tryptophan synthase activity
DNI27_RS06955	COG0277	FAD linked oxidase domain protein
DNI27_RS06960	COG0247	lactate metabolic process
DNI27_RS06965	COG1132	(ABC) transporter
DNI27_RS06970	COG1132	(ABC) transporter
DNI27_RS07025	COG0741	lytic transglycosylase activity
DNI27_RS07025	COG0791	NLP P60 protein
DNI27_RS07055	COG2946	Replication initiation factor
DNI27_RS07065	COG1674	ftsk spoiiie
DNI27_RS07090	COG3871	stress protein (general stress protein 26)
DNI27_RS07095	COG1115	amino acid carrier protein
DNI27_RS07100	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
DNI27_RS07105	COG2814	Major facilitator Superfamily
DNI27_RS07110	COG2271	Major facilitator Superfamily
DNI27_RS07115	COG3764	Sortase (surface protein transpeptidase)
DNI27_RS07120	COG1929	Belongs to the glycerate kinase type-1 family
DNI27_RS07130	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
DNI27_RS07150	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
DNI27_RS07155	COG0702	epimerase
DNI27_RS07160	COG4166	transmembrane transport
DNI27_RS07165	COG0444	Belongs to the ABC transporter superfamily
DNI27_RS07170	COG4608	Belongs to the ABC transporter superfamily
DNI27_RS07175	COG0601	transmembrane transport
DNI27_RS07180	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DNI27_RS07185	COG4166	transmembrane transport
DNI27_RS07190	COG0444	Belongs to the ABC transporter superfamily
DNI27_RS07195	COG4608	Belongs to the ABC transporter superfamily
DNI27_RS07200	COG0601	transmembrane transport
DNI27_RS07205	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DNI27_RS07215	COG1760	l-serine dehydratase
DNI27_RS07220	COG1760	l-serine dehydratase
DNI27_RS07270	COG0471	metal ion transport
DNI27_RS07275	COG2116	formate transmembrane transporter activity
DNI27_RS07280	COG0454	-acetyltransferase
DNI27_RS07290	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
DNI27_RS07290	COG1648	precorrin-2 dehydrogenase activity
DNI27_RS07295	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
DNI27_RS07300	COG2146	nitrite reductase [NAD(P)H] activity
DNI27_RS07305	COG1648	precorrin-2 dehydrogenase activity
DNI27_RS07305	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
DNI27_RS07310	COG0737	Belongs to the 5'-nucleotidase family
DNI27_RS07320	COG0018	arginyl-trna synthetase
DNI27_RS07335	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
DNI27_RS07340	COG1140	nitrate reductase beta subunit
DNI27_RS07350	COG2181	nitrate reductase activity
DNI27_RS07360	COG4585	Histidine kinase
DNI27_RS07365	COG2197	response regulator
DNI27_RS07370	COG2223	nitrite transmembrane transporter activity
DNI27_RS07380	COG4187	Peptidase family M20/M25/M40
DNI27_RS07390	COG0039	L-malate dehydrogenase activity
DNI27_RS07395	COG1363	Peptidase, m42
DNI27_RS07400	COG0697	spore germination
DNI27_RS07410	COG2807	transmembrane transport
DNI27_RS07420	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DNI27_RS07420	COG1263	PTS System
DNI27_RS07435	COG1283	sodium-dependent phosphate transmembrane transporter activity
DNI27_RS07455	COG0492	ferredoxin-NADP+ reductase activity
DNI27_RS07460	COG2814	Major facilitator Superfamily
DNI27_RS07465	COG0604	alcohol dehydrogenase
DNI27_RS07480	COG1620	l-lactate permease
DNI27_RS07485	COG0438	transferase activity, transferring glycosyl groups
DNI27_RS07490	COG0579	oxidoreductase
DNI27_RS07505	COG0577	efflux transmembrane transporter activity
DNI27_RS07545	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
DNI27_RS07555	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DNI27_RS07575	COG1304	FMN binding
DNI27_RS07580	COG0523	cobalamin synthesis protein
DNI27_RS07585	COG0786	glutamate:sodium symporter activity
DNI27_RS07590	COG2207	Transcriptional regulator
DNI27_RS07615	COG1757	Na H antiporter
DNI27_RS07620	COG2094	Belongs to the DNA glycosylase MPG family
DNI27_RS07625	COG3152	Membrane
DNI27_RS07630	COG4152	abc transporter atp-binding protein
DNI27_RS07635	COG1668	transmembrane transport
DNI27_RS07640	COG1742	UPF0060 membrane protein
DNI27_RS07645	COG2017	converts alpha-aldose to the beta-anomer
DNI27_RS07650	COG2258	MOSC domain
DNI27_RS07655	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
DNI27_RS07665	COG1266	CAAX protease self-immunity
DNI27_RS07670	COG0583	DNA-binding transcription factor activity
DNI27_RS07675	COG3314	Sporulation integral membrane protein YlbJ
DNI27_RS07680	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
DNI27_RS07685	COG1228	amidohydrolase
DNI27_RS07690	COG0659	secondary active sulfate transmembrane transporter activity
DNI27_RS07695	COG1473	amidohydrolase
DNI27_RS07715	COG0385	Bile acid
DNI27_RS07725	COG0346	lactoylglutathione lyase activity
DNI27_RS07730	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DNI27_RS07755	COG1113	amino acid transport
DNI27_RS07780	COG1316	TRANSCRIPTIONal
DNI27_RS07795	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
DNI27_RS07800	COG3383	formate dehydrogenase (NAD+) activity
DNI27_RS07825	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DNI27_RS07830	COG2076	Multidrug Resistance protein
DNI27_RS07835	COG2076	Multidrug Resistance protein
DNI27_RS07840	COG3942	CHAP domain
DNI27_RS07850	COG1757	Na H antiporter
DNI27_RS07860	COG3942	CHAP domain
DNI27_RS07880	COG1960	acyl-CoA dehydrogenase activity
DNI27_RS07885	COG2832	Protein of unknown function (DUF454)
DNI27_RS07890	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
DNI27_RS07895	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DNI27_RS07905	COG2186	Transcriptional regulator
DNI27_RS07915	COG1268	BioY protein
DNI27_RS07930	COG1609	Transcriptional regulator
DNI27_RS07935	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
DNI27_RS07940	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
DNI27_RS07945	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
DNI27_RS07955	COG4149	molybdate abc transporter
DNI27_RS07960	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
DNI27_RS07965	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
DNI27_RS07970	COG0521	Mo-molybdopterin cofactor biosynthetic process
DNI27_RS07990	COG0314	molybdopterin synthase activity
DNI27_RS08000	COG0746	molybdenum cofactor guanylyltransferase activity
DNI27_RS08005	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
DNI27_RS08030	COG2348	transferase activity, transferring amino-acyl groups
DNI27_RS08035	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DNI27_RS08040	COG0436	Aminotransferase
DNI27_RS08070	COG2252	PERMEase
DNI27_RS08090	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
DNI27_RS08095	COG0088	Forms part of the polypeptide exit tunnel
DNI27_RS08100	COG0089	rRNA binding
DNI27_RS08105	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
DNI27_RS08110	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
DNI27_RS08115	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
DNI27_RS08120	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
DNI27_RS08125	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
DNI27_RS08130	COG0255	Belongs to the universal ribosomal protein uL29 family
DNI27_RS08140	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
DNI27_RS08155	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
DNI27_RS08160	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
DNI27_RS08165	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
DNI27_RS08175	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
DNI27_RS08180	COG1841	ribosomal large subunit assembly
DNI27_RS08190	COG0201	protein transport
DNI27_RS08205	COG0257	Belongs to the bacterial ribosomal protein bL36 family
DNI27_RS08215	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
DNI27_RS08220	COG0202	RNA polymerase activity
DNI27_RS08225	COG0203	ribosomal protein L17
DNI27_RS08230	COG1122	ATPase activity
DNI27_RS08235	COG1122	ATPase activity
DNI27_RS08245	COG0101	tRNA pseudouridine synthase activity
DNI27_RS08250	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
DNI27_RS08270	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
DNI27_RS08310	COG1349	DNA-binding transcription factor activity
DNI27_RS08325	COG3684	Belongs to the aldolase LacD family
DNI27_RS08335	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DNI27_RS08335	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DNI27_RS08345	COG3513	CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
DNI27_RS08350	COG1518	maintenance of DNA repeat elements
DNI27_RS08370	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
DNI27_RS08385	COG1302	Protein conserved in bacteria
DNI27_RS08390	COG2814	Major facilitator Superfamily
DNI27_RS08395	COG4264	IucA IucC family
DNI27_RS08400	COG2814	Major facilitator Superfamily
DNI27_RS08405	COG4264	IucA IucC family
DNI27_RS08410	COG3457	Alanine racemase
DNI27_RS08415	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
DNI27_RS08420	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DNI27_RS08425	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DNI27_RS08430	COG3314	Sporulation integral membrane protein YlbJ
DNI27_RS08440	COG1988	membrane-bound metal-dependent
DNI27_RS08445	COG4284	Utp--glucose-1-phosphate uridylyltransferase
DNI27_RS08450	COG1272	protein, Hemolysin III
DNI27_RS08470	COG2814	Major facilitator Superfamily
DNI27_RS08475	COG0489	protein tyrosine kinase activity
DNI27_RS08540	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DNI27_RS08560	COG1119	ATPase activity
DNI27_RS08565	COG0561	phosphatase activity
DNI27_RS08580	COG2186	Transcriptional regulator
DNI27_RS08585	COG1482	cell wall glycoprotein biosynthetic process
DNI27_RS08600	COG1757	Na H antiporter
DNI27_RS08610	COG0813	purine-nucleoside phosphorylase activity
DNI27_RS08645	COG5146	pantothenate kinase activity
DNI27_RS08665	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DNI27_RS08675	COG0504	CTP synthase activity
DNI27_RS08685	COG2271	Major facilitator Superfamily
DNI27_RS08690	COG4821	SIS domain
DNI27_RS08695	COG0191	fructose-bisphosphate aldolase activity
DNI27_RS08700	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
DNI27_RS08705	COG1733	regulation of RNA biosynthetic process
DNI27_RS08720	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
DNI27_RS08725	COG0254	rRNA binding
DNI27_RS08735	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
DNI27_RS08740	COG2890	protein-(glutamine-N5) methyltransferase activity
DNI27_RS08745	COG0009	L-threonylcarbamoyladenylate synthase
DNI27_RS08750	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DNI27_RS08755	COG4475	Protein of unknown function (DUF436)
DNI27_RS08760	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
DNI27_RS08765	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
DNI27_RS08770	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
DNI27_RS08780	COG0356	it plays a direct role in the translocation of protons across the membrane
DNI27_RS08785	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
DNI27_RS08795	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
DNI27_RS08805	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
DNI27_RS08835	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
DNI27_RS08850	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
DNI27_RS08860	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
DNI27_RS08865	COG0352	thiamine-phosphate diphosphorylase activity
DNI27_RS08870	COG0706	membrane insertase activity
DNI27_RS08875	COG1418	mRNA catabolic process
DNI27_RS08880	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DNI27_RS08885	COG1937	Protein conserved in bacteria
DNI27_RS08900	COG2217	Heavy metal translocating P-type atpase
DNI27_RS08920	COG0772	Belongs to the SEDS family
DNI27_RS08925	COG1181	Belongs to the D-alanine--D-alanine ligase family
DNI27_RS08930	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
DNI27_RS08935	COG0513	Belongs to the DEAD box helicase family
DNI27_RS08950	COG3402	PFAM membrane-flanked domain
DNI27_RS08955	COG0736	holo-[acyl-carrier-protein] synthase activity
DNI27_RS08960	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
DNI27_RS08970	COG2337	Toxic component of a toxin-antitoxin (TA) module
DNI27_RS08975	COG2208	phosphoserine phosphatase activity
DNI27_RS08980	COG1366	Belongs to the anti-sigma-factor antagonist family
DNI27_RS08990	COG1191	sigma factor activity
DNI27_RS08995	COG2183	response to ionizing radiation
DNI27_RS09000	COG3091	SprT-like family
DNI27_RS09035	COG0515	serine threonine protein kinase
DNI27_RS09055	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
DNI27_RS09065	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DNI27_RS09070	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
DNI27_RS09080	COG0028	Belongs to the TPP enzyme family
DNI27_RS09085	COG0129	dihydroxy-acid dehydratase activity
DNI27_RS09090	COG0802	atpase or kinase
DNI27_RS09095	COG1214	PFAM Peptidase M22, glycoprotease
DNI27_RS09100	COG0456	acetyltransferase
DNI27_RS09105	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
DNI27_RS09115	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
DNI27_RS09120	COG0488	(ABC) transporter
DNI27_RS09125	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
DNI27_RS09130	COG2814	Major facilitator Superfamily
DNI27_RS09135	COG1846	Transcriptional regulator
DNI27_RS09145	COG2124	cytochrome p450
DNI27_RS09155	COG1609	Transcriptional regulator
DNI27_RS09160	COG1621	beta-fructofuranosidase activity
DNI27_RS09165	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DNI27_RS09185	COG4512	PFAM Accessory gene regulator B
DNI27_RS09225	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DNI27_RS09230	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
DNI27_RS09250	COG1131	(ABC) transporter
DNI27_RS09265	COG1070	Carbohydrate kinase
DNI27_RS09270	COG2610	gluconate transmembrane transporter activity
DNI27_RS09305	COG2706	6-phosphogluconolactonase activity
DNI27_RS09310	COG1012	belongs to the aldehyde dehydrogenase family
DNI27_RS09320	COG1227	inorganic diphosphatase activity
DNI27_RS09325	COG1335	isochorismatase
DNI27_RS09335	COG0077	Prephenate dehydratase
DNI27_RS09345	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
DNI27_RS09355	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
DNI27_RS09365	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
DNI27_RS09370	COG4496	protein, YerC YecD
DNI27_RS09375	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
DNI27_RS09380	COG0210	DNA helicase
DNI27_RS09385	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
DNI27_RS09390	COG4851	CamS sex pheromone cAM373 precursor
DNI27_RS09395	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DNI27_RS09400	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DNI27_RS09410	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DNI27_RS09415	COG1597	lipid kinase activity
DNI27_RS09440	COG0488	(ABC) transporter
DNI27_RS09450	COG1396	sequence-specific DNA binding
DNI27_RS09460	COG2211	Major facilitator Superfamily
DNI27_RS09470	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DNI27_RS09480	COG1528	Iron-storage protein
DNI27_RS09495	COG4129	membrane
DNI27_RS09500	COG0024	Methionine aminopeptidase
DNI27_RS09525	COG0288	reversible hydration of carbon dioxide
DNI27_RS09530	COG1295	ribonuclease BN
DNI27_RS09545	COG4840	Belongs to the UPF0435 family
DNI27_RS09550	COG2309	aminopeptidase activity
DNI27_RS09555	COG1607	acyl-coa hydrolase
DNI27_RS09560	COG0535	radical SAM domain protein
DNI27_RS09570	COG0693	protein deglycase activity
DNI27_RS09575	COG0028	Belongs to the TPP enzyme family
DNI27_RS09580	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DNI27_RS09585	COG2137	regulation of response to DNA damage stimulus
DNI27_RS09595	COG1388	LysM domain
DNI27_RS09595	COG1134	teichoic acid transport
DNI27_RS09605	COG1988	membrane-bound metal-dependent
DNI27_RS09610	COG1194	a g-specific adenine glycosylase
DNI27_RS09615	COG3557	Belongs to the UPF0374 family
DNI27_RS09625	COG0069	glutamate synthase activity
DNI27_RS09630	COG4129	membrane
DNI27_RS09635	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
DNI27_RS09640	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
DNI27_RS09650	COG0735	belongs to the Fur family
DNI27_RS09875	COG0765	amino acid transport
DNI27_RS09880	COG1126	abc transporter atp-binding protein
DNI27_RS09885	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
DNI27_RS09895	COG0363	glucosamine-6-phosphate deaminase activity
DNI27_RS09910	COG0114	fumarate hydratase activity
DNI27_RS09915	COG0248	Ppx GppA phosphatase
DNI27_RS09920	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
DNI27_RS09925	COG0564	pseudouridine synthase activity
DNI27_RS09930	COG2203	Gaf domain
DNI27_RS09930	COG4585	Histidine kinase
DNI27_RS09935	COG2197	response regulator
DNI27_RS09945	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
DNI27_RS09955	COG4399	Belongs to the UPF0754 family
DNI27_RS09960	COG3679	Belongs to the UPF0342 family
DNI27_RS09965	COG0420	3'-5' exonuclease activity
DNI27_RS09975	COG3481	metal-dependent phosphohydrolase, HD sub domain
DNI27_RS09980	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
DNI27_RS09995	COG1846	Transcriptional regulator
DNI27_RS10005	COG0537	adenosine 5'-monophosphoramidase activity
DNI27_RS10010	COG1131	(ABC) transporter
DNI27_RS10015	COG4473	ABC transporter
DNI27_RS10030	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
DNI27_RS10040	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
DNI27_RS10045	COG3545	Serine hydrolase
DNI27_RS10135	COG3037	sugar-specific permease SgaT UlaA
DNI27_RS10155	COG3623	hexulose-6-phosphate isomerase
DNI27_RS10160	COG0235	Class ii aldolase
DNI27_RS10180	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
DNI27_RS10185	COG0494	nUDIX hydrolase
DNI27_RS10190	COG1506	peptidase
DNI27_RS10195	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
DNI27_RS10200	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
DNI27_RS10210	COG0656	L-ascorbic acid biosynthetic process
DNI27_RS10215	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
DNI27_RS10220	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
DNI27_RS10230	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
DNI27_RS10255	COG3266	domain, Protein
DNI27_RS10255	COG5632	N-Acetylmuramoyl-L-alanine amidase
DNI27_RS10255	COG4193	domain, Protein
DNI27_RS10265	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
DNI27_RS10265	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
DNI27_RS10270	COG0307	riboflavin synthase, alpha
DNI27_RS10275	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
DNI27_RS10275	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
DNI27_RS10280	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
DNI27_RS10295	COG2267	carboxylic ester hydrolase activity
DNI27_RS10300	COG0039	L-malate dehydrogenase activity
DNI27_RS10310	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
DNI27_RS10315	COG1242	4 iron, 4 sulfur cluster binding
DNI27_RS10320	COG2814	Major facilitator Superfamily
DNI27_RS10325	COG0495	leucyl-tRNA aminoacylation
DNI27_RS10330	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
DNI27_RS10335	COG2081	HI0933 family
DNI27_RS10340	COG2244	polysaccharide biosynthetic process
DNI27_RS10345	COG1187	pseudouridine synthase activity
DNI27_RS10355	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DNI27_RS10360	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
DNI27_RS10365	COG0510	thiamine kinase activity
DNI27_RS10370	COG0220	tRNA (guanine-N7-)-methyltransferase activity
DNI27_RS10375	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DNI27_RS10385	COG1363	Peptidase, m42
DNI27_RS10390	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DNI27_RS10395	COG4848	Belongs to the UPF0354 family
DNI27_RS10400	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DNI27_RS10405	COG1674	ftsk spoiiie
DNI27_RS10410	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
DNI27_RS10415	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
DNI27_RS10425	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
DNI27_RS10425	COG1605	Chorismate mutase
DNI27_RS10430	COG1609	Transcriptional regulator
DNI27_RS10440	COG0454	-acetyltransferase
DNI27_RS10445	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DNI27_RS10450	COG2759	Belongs to the formate--tetrahydrofolate ligase family
DNI27_RS10455	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
DNI27_RS10465	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DNI27_RS10470	COG0204	Acyl-transferase
DNI27_RS10480	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
DNI27_RS10485	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
DNI27_RS10490	COG1764	response to oxidative stress
DNI27_RS10530	COG0456	acetyltransferase
DNI27_RS10565	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
DNI27_RS10570	COG1956	GAF domain-containing protein
DNI27_RS10575	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
DNI27_RS10580	COG1104	cysteine desulfurase activity
DNI27_RS10585	COG0301	tRNA thio-modification
DNI27_RS10595	COG0616	signal peptide processing
DNI27_RS10600	COG1714	RDD family
DNI27_RS10605	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
DNI27_RS10610	COG0827	DNA restriction-modification system
DNI27_RS10615	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
DNI27_RS10620	COG0589	response to stress
DNI27_RS10625	COG0686	Belongs to the AlaDH PNT family
DNI27_RS10635	COG0006	proline dipeptidase activity
DNI27_RS10640	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
DNI27_RS10650	COG4109	DRTGG domain
DNI27_RS10655	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
DNI27_RS10660	COG0587	DNA-directed DNA polymerase activity
DNI27_RS10665	COG0281	malic enzyme
DNI27_RS10670	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
DNI27_RS10675	COG0825	malonyl-CoA metabolic process
DNI27_RS10680	COG0205	6-phosphofructokinase activity
DNI27_RS10685	COG0469	pyruvate kinase activity
DNI27_RS10690	COG0372	Belongs to the citrate synthase family
DNI27_RS10695	COG0538	isocitrate dehydrogenase activity
DNI27_RS10700	COG0745	RESPONSE REGULATOR receiver
DNI27_RS10705	COG5002	protein histidine kinase activity
DNI27_RS10710	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DNI27_RS10710	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DNI27_RS10720	COG0237	dephospho-CoA kinase activity
DNI27_RS10735	COG3611	Membrane attachment protein
DNI27_RS10740	COG1484	DNA-dependent DNA replication
DNI27_RS10750	COG0833	amino acid
DNI27_RS10760	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
DNI27_RS10765	COG0291	Belongs to the bacterial ribosomal protein bL35 family
DNI27_RS10770	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
DNI27_RS10785	COG0544	peptidyl-prolyl cis-trans isomerase activity
DNI27_RS10795	COG0218	Necessary for normal cell division and for the maintenance of normal septation
DNI27_RS10800	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
DNI27_RS10810	COG0181	hydroxymethylbilane synthase activity
DNI27_RS10825	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
DNI27_RS10835	COG2818	Glycosylase
DNI27_RS10840	COG0525	valine-tRNA ligase activity
DNI27_RS10845	COG0285	dihydrofolate synthase activity
DNI27_RS10855	COG2003	Belongs to the UPF0758 family
DNI27_RS10890	COG2868	ribosomal protein
DNI27_RS10900	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
DNI27_RS10910	COG0632	four-way junction helicase activity
DNI27_RS10920	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
DNI27_RS10930	COG1862	Preprotein translocase
DNI27_RS10935	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DNI27_RS10935	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DNI27_RS10940	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
DNI27_RS10940	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
DNI27_RS10945	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
DNI27_RS10955	COG1490	D-aminoacyl-tRNA deacylase activity
DNI27_RS10960	COG0860	N-Acetylmuramoyl-L-alanine amidase
DNI27_RS10970	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
DNI27_RS10980	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
DNI27_RS10985	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
DNI27_RS10990	COG1959	2 iron, 2 sulfur cluster binding
DNI27_RS11005	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DNI27_RS11010	COG1104	cysteine desulfurase activity
DNI27_RS11015	COG0482	sulfurtransferase activity
DNI27_RS11025	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
DNI27_RS11030	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
DNI27_RS11035	COG4472	Bacterial protein of unknown function (DUF965)
DNI27_RS11040	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
DNI27_RS11045	COG3906	Belongs to the UPF0473 family
DNI27_RS11050	COG4122	O-methyltransferase activity
DNI27_RS11055	COG0826	peptidase U32
DNI27_RS11060	COG0826	peptidase U32
DNI27_RS11065	COG0572	uridine kinase
DNI27_RS11075	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
DNI27_RS11080	COG1984	allophanate hydrolase subunit 2
DNI27_RS11085	COG0511	ligase activity, forming carbon-carbon bonds
DNI27_RS11090	COG0439	Biotin carboxylase
DNI27_RS11095	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
DNI27_RS11100	COG1914	H( )-stimulated, divalent metal cation uptake system
DNI27_RS11105	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
DNI27_RS11110	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
DNI27_RS11115	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
DNI27_RS11120	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
DNI27_RS11125	COG1534	Rna-binding protein
DNI27_RS11135	COG1713	HD superfamily hydrolase involved in NAD metabolism
DNI27_RS11140	COG0799	negative regulation of ribosome biogenesis
DNI27_RS11145	COG2226	methyltransferase
DNI27_RS11150	COG1555	photosystem II stabilization
DNI27_RS11150	COG1596	polysaccharide export
DNI27_RS11155	COG2131	deaminase
DNI27_RS11160	COG2333	competence protein COMEC
DNI27_RS11160	COG0658	competence protein
DNI27_RS11165	COG1466	dna polymerase III delta subunit
DNI27_RS11170	COG0268	Binds directly to 16S ribosomal RNA
DNI27_RS11180	COG0635	Involved in the biosynthesis of porphyrin-containing compound
DNI27_RS11195	COG0443	Heat shock 70 kDa protein
DNI27_RS11200	COG0484	heat shock protein binding
DNI27_RS11205	COG2264	protein methyltransferase activity
DNI27_RS11210	COG1385	rRNA (uridine-N3-)-methyltransferase activity
DNI27_RS11215	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
DNI27_RS11230	COG1030	water channel activity
DNI27_RS11235	COG4864	UPF0365 protein
DNI27_RS11245	COG1702	phosphate starvation-inducible protein PhoH
DNI27_RS11255	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
DNI27_RS11265	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
DNI27_RS11270	COG1381	Involved in DNA repair and RecF pathway recombination
DNI27_RS11275	COG0423	glycine-tRNA ligase activity
DNI27_RS11280	COG0517	IMP dehydrogenase activity
DNI27_RS11285	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
DNI27_RS11290	COG0358	DNA primase activity
DNI27_RS11295	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
DNI27_RS11300	COG2384	SAM-dependent methyltransferase
DNI27_RS11305	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
DNI27_RS11310	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
DNI27_RS11315	COG0513	Belongs to the DEAD box helicase family
DNI27_RS11320	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
DNI27_RS11325	COG1121	(ABC) transporter
DNI27_RS11330	COG1108	ABC-type Mn2 Zn2 transport systems permease components
DNI27_RS11335	COG0735	belongs to the Fur family
DNI27_RS11340	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
DNI27_RS11350	COG0768	penicillin binding
DNI27_RS11355	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
DNI27_RS11360	COG0573	inorganic phosphate transmembrane transporter activity
DNI27_RS11365	COG0581	inorganic phosphate transmembrane transporter activity
DNI27_RS11370	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
DNI27_RS11375	COG0704	Plays a role in the regulation of phosphate uptake
DNI27_RS11385	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
DNI27_RS11390	COG0705	Rhomboid family
DNI27_RS11390	COG0457	Tetratricopeptide repeat
DNI27_RS11395	COG4483	Protein conserved in bacteria
DNI27_RS11400	COG1940	carbohydrate kinase activity
DNI27_RS11405	COG0011	TIGRFAM Protein of
DNI27_RS11410	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DNI27_RS11415	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
DNI27_RS11445	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
DNI27_RS11450	COG0404	The glycine cleavage system catalyzes the degradation of glycine
DNI27_RS11460	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
DNI27_RS11465	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
DNI27_RS11470	COG0095	Lipoate-protein ligase
DNI27_RS11485	COG0006	proline dipeptidase activity
DNI27_RS11490	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
DNI27_RS11495	COG0511	ligase activity, forming carbon-carbon bonds
DNI27_RS11500	COG0439	Biotin carboxylase
DNI27_RS11505	COG1302	Protein conserved in bacteria
DNI27_RS11515	COG1570	exodeoxyribonuclease VII activity
DNI27_RS11520	COG1722	exodeoxyribonuclease VII activity
DNI27_RS11525	COG0142	geranyltranstransferase activity
DNI27_RS11530	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
DNI27_RS11535	COG1438	arginine binding
DNI27_RS11540	COG0497	DNA recombination
DNI27_RS11545	COG0280	phosphate acetyltransferase
DNI27_RS11550	COG3426	butyrate kinase activity
DNI27_RS11555	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DNI27_RS11560	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
DNI27_RS11565	COG0022	dehydrogenase e1 component
DNI27_RS11570	COG0508	dehydrogenase complex catalyzes the overall conversion of
DNI27_RS11580	COG4129	membrane
DNI27_RS11590	COG2195	Cleaves the N-terminal amino acid of tripeptides
DNI27_RS11620	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
DNI27_RS11625	COG1234	tRNA 3'-trailer cleavage
DNI27_RS11630	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
DNI27_RS11640	COG0667	Aldo Keto reductase
DNI27_RS11645	COG0494	nUDIX hydrolase
DNI27_RS11650	COG0735	belongs to the Fur family
DNI27_RS11665	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
DNI27_RS11670	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
DNI27_RS11675	COG1187	pseudouridine synthase activity
DNI27_RS11680	COG0745	RESPONSE REGULATOR receiver
DNI27_RS11695	COG1141	Ferredoxin
DNI27_RS11705	COG0514	ATP-dependent DNA helicase (RecQ)
DNI27_RS11715	COG0492	ferredoxin-NADP+ reductase activity
DNI27_RS11720	COG0252	asparaginase activity
DNI27_RS11730	COG0539	negative regulation of cytoplasmic translation
DNI27_RS11735	COG1160	GTP binding
DNI27_RS11740	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
DNI27_RS11760	COG0142	geranyltranstransferase activity
DNI27_RS11765	COG0105	UTP biosynthetic process
DNI27_RS11775	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
DNI27_RS11785	COG0457	Tetratricopeptide repeat
DNI27_RS11790	COG5582	Belongs to the UPF0302 family
DNI27_RS11795	COG4347	Protein of unknown function (DUF1405)
DNI27_RS11805	COG1694	Mazg nucleotide pyrophosphohydrolase
DNI27_RS11810	COG0438	transferase activity, transferring glycosyl groups
DNI27_RS11815	COG0617	tRNA 3'-terminal CCA addition
DNI27_RS11830	COG0017	Asparaginyl-tRNA synthetase
DNI27_RS11835	COG3935	DnaD domain protein
DNI27_RS11840	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
DNI27_RS11850	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DNI27_RS11850	COG4499	WXG100 protein secretion system (Wss), protein YukC
DNI27_RS11865	COG4474	Belongs to the UPF0398 family
DNI27_RS11870	COG3599	regulation of cell shape
DNI27_RS11880	COG0116	Belongs to the methyltransferase superfamily
DNI27_RS11885	COG2962	Rard protein
DNI27_RS11890	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
DNI27_RS11895	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DNI27_RS11905	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
DNI27_RS11915	COG1413	lyase activity
DNI27_RS11950	COG2190	(PTS) system
DNI27_RS11960	COG0793	Belongs to the peptidase S41A family
DNI27_RS11970	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
DNI27_RS11975	COG0671	phosphoesterase, PA-phosphatase related
DNI27_RS11985	COG5002	protein histidine kinase activity
DNI27_RS11990	COG0567	Dehydrogenase, E1 component
DNI27_RS12015	COG0714	Associated with various cellular activities
DNI27_RS12020	COG4548	von Willebrand factor, type A
DNI27_RS12025	COG1114	Component of the transport system for branched-chain amino acids
DNI27_RS12030	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
DNI27_RS12035	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
DNI27_RS12045	COG3853	Toxic anion resistance protein (TelA)
DNI27_RS12065	COG1278	Cold shock
DNI27_RS12085	COG1473	amidohydrolase
DNI27_RS12090	COG2171	N-acyltransferase activity
DNI27_RS12095	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
DNI27_RS12100	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DNI27_RS12105	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
DNI27_RS12110	COG0488	(ABC) transporter
DNI27_RS12115	COG2996	Protein conserved in bacteria
DNI27_RS12145	COG1363	Peptidase, m42
DNI27_RS12150	COG0287	Prephenate dehydrogenase
DNI27_RS12155	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DNI27_RS12165	COG1942	4-Oxalocrotonate Tautomerase
DNI27_RS12185	COG0628	permease
DNI27_RS12195	COG3711	transcriptional antiterminator
DNI27_RS12200	COG1115	amino acid carrier protein
DNI27_RS12205	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
DNI27_RS12215	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
DNI27_RS12220	COG4841	protein insertion into membrane
DNI27_RS12225	COG0824	Thioesterase
DNI27_RS12235	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
DNI27_RS12240	COG1970	mechanosensitive ion channel activity
DNI27_RS12245	COG0419	ATPase involved in DNA repair
DNI27_RS12250	COG0420	3'-5' exonuclease activity
DNI27_RS12255	COG4846	Membrane protein involved in cytochrome C biogenesis
DNI27_RS12260	COG3763	UPF0154 protein
DNI27_RS12270	COG4224	UPF0291 protein
DNI27_RS12280	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
DNI27_RS12290	COG0516	GMP reductase activity
DNI27_RS12295	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
DNI27_RS12305	COG0833	amino acid
DNI27_RS12320	COG0083	homoserine kinase activity
DNI27_RS12325	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
DNI27_RS12330	COG0460	homoserine dehydrogenase
DNI27_RS12335	COG0527	aspartate kinase activity
DNI27_RS12360	COG1525	nuclease
DNI27_RS12390	COG0584	glycerophosphoryl diester phosphodiesterase
DNI27_RS12410	COG0789	Transcriptional regulator
DNI27_RS12415	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
DNI27_RS12420	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
DNI27_RS12425	COG0386	Belongs to the glutathione peroxidase family
DNI27_RS12430	COG2267	carboxylic ester hydrolase activity
DNI27_RS12435	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
DNI27_RS12440	COG1923	regulation of RNA biosynthetic process
DNI27_RS12445	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
DNI27_RS12455	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
DNI27_RS12460	COG1619	proteins homologs of microcin C7 resistance protein MccF
DNI27_RS12465	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
DNI27_RS12470	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
DNI27_RS12490	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
DNI27_RS12500	COG1013	pyruvate-flavodoxin oxidoreductase activity
DNI27_RS12505	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
DNI27_RS12505	COG0674	pyruvate-flavodoxin oxidoreductase activity
DNI27_RS12510	COG1692	metallophosphoesterase
DNI27_RS12530	COG1418	mRNA catabolic process
DNI27_RS12535	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
DNI27_RS12540	COG1058	Belongs to the CinA family
DNI27_RS12540	COG1546	Belongs to the CinA family
DNI27_RS12560	COG0300	oxidoreductase activity
DNI27_RS12565	COG0612	Peptidase, M16
DNI27_RS12570	COG0612	Peptidase, M16
DNI27_RS12575	COG2188	Transcriptional regulator
DNI27_RS12590	COG1185	polyribonucleotide nucleotidyltransferase activity
DNI27_RS12600	COG0196	riboflavin kinase activity
DNI27_RS12605	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
DNI27_RS12610	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
DNI27_RS12650	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DNI27_RS12680	COG1780	Probably involved in ribonucleotide reductase function
DNI27_RS12725	COG0270	DNA (cytosine-5-)-methyltransferase activity
DNI27_RS12790	COG0587	DNA-directed DNA polymerase activity
DNI27_RS12795	COG0587	DNA-directed DNA polymerase activity
DNI27_RS12805	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
DNI27_RS13050	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
DNI27_RS13070	COG2887	Belongs to the helicase family. UvrD subfamily
DNI27_RS13195	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
DNI27_RS13225	COG4373	Mu-like prophage FluMu protein gp28
DNI27_RS13295	COG0582	viral genome integration into host DNA
DNI27_RS13300	COG0739	heme binding
DNI27_RS13300	COG0741	lytic transglycosylase activity
DNI27_RS13300	COG1196	nuclear chromosome segregation
DNI27_RS13300	COG0739	heme binding
DNI27_RS13300	COG0741	lytic transglycosylase activity
DNI27_RS13300	COG1196	nuclear chromosome segregation