locus-tag	class	description
GAN19_RS00010	COG5632	N-Acetylmuramoyl-L-alanine amidase
GAN19_RS00010	COG4193	domain, Protein
GAN19_RS00010	COG3266	domain, Protein
GAN19_RS00035	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
GAN19_RS00045	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GAN19_RS00050	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GAN19_RS00055	COG0656	L-ascorbic acid biosynthetic process
GAN19_RS00065	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
GAN19_RS00070	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
GAN19_RS00075	COG1506	peptidase
GAN19_RS00080	COG0494	nUDIX hydrolase
GAN19_RS00085	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
GAN19_RS00105	COG0235	Class ii aldolase
GAN19_RS00110	COG3623	hexulose-6-phosphate isomerase
GAN19_RS00130	COG3037	sugar-specific permease SgaT UlaA
GAN19_RS00220	COG3545	Serine hydrolase
GAN19_RS00225	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
GAN19_RS00235	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
GAN19_RS00245	COG3344	reverse transcriptase
GAN19_RS00250	COG4473	ABC transporter
GAN19_RS00255	COG1131	(ABC) transporter
GAN19_RS00260	COG0537	adenosine 5'-monophosphoramidase activity
GAN19_RS00270	COG1846	Transcriptional regulator
GAN19_RS00285	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GAN19_RS00290	COG3481	metal-dependent phosphohydrolase, HD sub domain
GAN19_RS00300	COG0420	3'-5' exonuclease activity
GAN19_RS00305	COG3679	Belongs to the UPF0342 family
GAN19_RS00310	COG4399	Belongs to the UPF0754 family
GAN19_RS00325	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
GAN19_RS00335	COG2197	response regulator
GAN19_RS00340	COG2203	Gaf domain
GAN19_RS00340	COG4585	Histidine kinase
GAN19_RS00345	COG0564	pseudouridine synthase activity
GAN19_RS00350	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
GAN19_RS00355	COG0248	Ppx GppA phosphatase
GAN19_RS00360	COG0114	fumarate hydratase activity
GAN19_RS00370	COG0363	glucosamine-6-phosphate deaminase activity
GAN19_RS00380	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
GAN19_RS00385	COG1126	abc transporter atp-binding protein
GAN19_RS00390	COG0765	amino acid transport
GAN19_RS00555	COG0735	belongs to the Fur family
GAN19_RS00565	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
GAN19_RS00570	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
GAN19_RS00575	COG4129	membrane
GAN19_RS00580	COG0069	glutamate synthase activity
GAN19_RS00590	COG3557	Belongs to the UPF0374 family
GAN19_RS00595	COG1194	a g-specific adenine glycosylase
GAN19_RS00600	COG1988	membrane-bound metal-dependent
GAN19_RS00610	COG1388	LysM domain
GAN19_RS00610	COG1134	teichoic acid transport
GAN19_RS00620	COG2137	regulation of response to DNA damage stimulus
GAN19_RS00625	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GAN19_RS00630	COG0028	Belongs to the TPP enzyme family
GAN19_RS00635	COG0693	protein deglycase activity
GAN19_RS00640	COG0535	radical SAM domain protein
GAN19_RS00645	COG1607	acyl-coa hydrolase
GAN19_RS00650	COG2309	aminopeptidase activity
GAN19_RS00655	COG4840	Belongs to the UPF0435 family
GAN19_RS00670	COG1295	ribonuclease BN
GAN19_RS00675	COG0288	reversible hydration of carbon dioxide
GAN19_RS00700	COG0024	Methionine aminopeptidase
GAN19_RS00705	COG4129	membrane
GAN19_RS00720	COG1528	Iron-storage protein
GAN19_RS00730	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GAN19_RS00740	COG2211	Major facilitator Superfamily
GAN19_RS00750	COG1396	sequence-specific DNA binding
GAN19_RS00760	COG0488	(ABC) transporter
GAN19_RS00785	COG1597	lipid kinase activity
GAN19_RS00790	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GAN19_RS00800	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GAN19_RS00805	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GAN19_RS00810	COG4851	CamS sex pheromone cAM373 precursor
GAN19_RS00815	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
GAN19_RS00820	COG0210	DNA helicase
GAN19_RS00825	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
GAN19_RS00830	COG4496	protein, YerC YecD
GAN19_RS00835	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
GAN19_RS00845	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
GAN19_RS00855	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
GAN19_RS00865	COG1605	Chorismate mutase
GAN19_RS00865	COG0077	Prephenate dehydratase
GAN19_RS00875	COG1335	isochorismatase
GAN19_RS00880	COG1227	inorganic diphosphatase activity
GAN19_RS00890	COG1012	belongs to the aldehyde dehydrogenase family
GAN19_RS00895	COG2706	6-phosphogluconolactonase activity
GAN19_RS00925	COG2610	gluconate transmembrane transporter activity
GAN19_RS00930	COG1070	Carbohydrate kinase
GAN19_RS00945	COG1131	(ABC) transporter
GAN19_RS00960	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GAN19_RS00965	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GAN19_RS01005	COG4512	PFAM Accessory gene regulator B
GAN19_RS01025	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GAN19_RS01030	COG1621	beta-fructofuranosidase activity
GAN19_RS01035	COG1609	Transcriptional regulator
GAN19_RS01045	COG2124	cytochrome p450
GAN19_RS01055	COG1846	Transcriptional regulator
GAN19_RS01060	COG2814	Major facilitator Superfamily
GAN19_RS01065	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
GAN19_RS01070	COG0488	(ABC) transporter
GAN19_RS01075	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
GAN19_RS01085	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
GAN19_RS01090	COG0456	acetyltransferase
GAN19_RS01095	COG1214	PFAM Peptidase M22, glycoprotease
GAN19_RS01100	COG0802	atpase or kinase
GAN19_RS01105	COG0129	dihydroxy-acid dehydratase activity
GAN19_RS01110	COG0028	Belongs to the TPP enzyme family
GAN19_RS01120	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
GAN19_RS01125	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GAN19_RS01135	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
GAN19_RS01180	COG3091	SprT-like family
GAN19_RS01185	COG2183	response to ionizing radiation
GAN19_RS01190	COG1191	sigma factor activity
GAN19_RS01200	COG1366	Belongs to the anti-sigma-factor antagonist family
GAN19_RS01205	COG2208	phosphoserine phosphatase activity
GAN19_RS01210	COG2337	Toxic component of a toxin-antitoxin (TA) module
GAN19_RS01220	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GAN19_RS01225	COG0736	holo-[acyl-carrier-protein] synthase activity
GAN19_RS01230	COG3402	PFAM membrane-flanked domain
GAN19_RS01245	COG0513	Belongs to the DEAD box helicase family
GAN19_RS01250	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
GAN19_RS01255	COG1181	Belongs to the D-alanine--D-alanine ligase family
GAN19_RS01260	COG0772	Belongs to the SEDS family
GAN19_RS01270	COG2217	Heavy metal translocating P-type atpase
GAN19_RS01285	COG1937	Protein conserved in bacteria
GAN19_RS01290	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GAN19_RS01295	COG1418	mRNA catabolic process
GAN19_RS01300	COG0706	membrane insertase activity
GAN19_RS01305	COG0352	thiamine-phosphate diphosphorylase activity
GAN19_RS01310	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
GAN19_RS01320	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
GAN19_RS01335	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
GAN19_RS01365	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
GAN19_RS01375	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GAN19_RS01385	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GAN19_RS01390	COG0356	it plays a direct role in the translocation of protons across the membrane
GAN19_RS01400	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
GAN19_RS01405	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
GAN19_RS01410	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
GAN19_RS01415	COG4475	Protein of unknown function (DUF436)
GAN19_RS01420	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GAN19_RS01425	COG0009	L-threonylcarbamoyladenylate synthase
GAN19_RS01430	COG2890	protein-(glutamine-N5) methyltransferase activity
GAN19_RS01435	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
GAN19_RS01445	COG0254	rRNA binding
GAN19_RS01450	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
GAN19_RS01465	COG1733	regulation of RNA biosynthetic process
GAN19_RS01470	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GAN19_RS01475	COG0191	fructose-bisphosphate aldolase activity
GAN19_RS01480	COG4821	SIS domain
GAN19_RS01485	COG2271	Major facilitator Superfamily
GAN19_RS01490	COG0504	CTP synthase activity
GAN19_RS01500	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GAN19_RS01515	COG5146	pantothenate kinase activity
GAN19_RS01550	COG0813	purine-nucleoside phosphorylase activity
GAN19_RS01560	COG1757	Na H antiporter
GAN19_RS01575	COG1482	cell wall glycoprotein biosynthetic process
GAN19_RS01580	COG2186	Transcriptional regulator
GAN19_RS01590	COG0561	phosphatase activity
GAN19_RS01595	COG1119	ATPase activity
GAN19_RS01610	COG3421	Type III restriction
GAN19_RS01615	COG2189	Belongs to the N(4) N(6)-methyltransferase family
GAN19_RS01635	COG0210	DNA helicase
GAN19_RS01640	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
GAN19_RS01685	COG3711	transcriptional antiterminator
GAN19_RS01700	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GAN19_RS01765	COG0489	protein tyrosine kinase activity
GAN19_RS01770	COG2814	Major facilitator Superfamily
GAN19_RS01790	COG1272	protein, Hemolysin III
GAN19_RS01795	COG4284	Utp--glucose-1-phosphate uridylyltransferase
GAN19_RS01800	COG1988	membrane-bound metal-dependent
GAN19_RS01810	COG3314	Sporulation integral membrane protein YlbJ
GAN19_RS01815	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GAN19_RS01820	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GAN19_RS01825	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
GAN19_RS01830	COG3457	Alanine racemase
GAN19_RS01835	COG4264	IucA IucC family
GAN19_RS01840	COG2814	Major facilitator Superfamily
GAN19_RS01845	COG4264	IucA IucC family
GAN19_RS01850	COG2814	Major facilitator Superfamily
GAN19_RS01855	COG1302	Protein conserved in bacteria
GAN19_RS01870	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
GAN19_RS01880	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GAN19_RS01885	COG0488	(ABC) transporter
GAN19_RS01895	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GAN19_RS01895	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GAN19_RS01905	COG3684	Belongs to the aldolase LacD family
GAN19_RS01920	COG1349	DNA-binding transcription factor activity
GAN19_RS01960	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GAN19_RS01985	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
GAN19_RS01990	COG0101	tRNA pseudouridine synthase activity
GAN19_RS02000	COG1122	ATPase activity
GAN19_RS02005	COG1122	ATPase activity
GAN19_RS02010	COG0203	ribosomal protein L17
GAN19_RS02015	COG0202	RNA polymerase activity
GAN19_RS02020	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
GAN19_RS02030	COG0257	Belongs to the bacterial ribosomal protein bL36 family
GAN19_RS02045	COG0201	protein transport
GAN19_RS02055	COG1841	ribosomal large subunit assembly
GAN19_RS02060	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
GAN19_RS02070	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
GAN19_RS02075	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
GAN19_RS02080	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
GAN19_RS02095	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
GAN19_RS02105	COG0255	Belongs to the universal ribosomal protein uL29 family
GAN19_RS02110	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
GAN19_RS02115	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
GAN19_RS02120	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
GAN19_RS02125	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
GAN19_RS02130	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
GAN19_RS02135	COG0089	rRNA binding
GAN19_RS02140	COG0088	Forms part of the polypeptide exit tunnel
GAN19_RS02145	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
GAN19_RS02165	COG2252	PERMEase
GAN19_RS02190	COG0436	Aminotransferase
GAN19_RS02195	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GAN19_RS02200	COG2348	transferase activity, transferring amino-acyl groups
GAN19_RS02225	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
GAN19_RS02230	COG0746	molybdenum cofactor guanylyltransferase activity
GAN19_RS02240	COG0314	molybdopterin synthase activity
GAN19_RS02260	COG0521	Mo-molybdopterin cofactor biosynthetic process
GAN19_RS02265	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
GAN19_RS02270	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
GAN19_RS02275	COG4149	molybdate abc transporter
GAN19_RS02285	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
GAN19_RS02290	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
GAN19_RS02295	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
GAN19_RS02300	COG1609	Transcriptional regulator
GAN19_RS02315	COG1268	BioY protein
GAN19_RS02325	COG2186	Transcriptional regulator
GAN19_RS02335	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GAN19_RS02340	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GAN19_RS02345	COG2832	Protein of unknown function (DUF454)
GAN19_RS02350	COG1388	LysM domain
GAN19_RS02350	COG5632	N-Acetylmuramoyl-L-alanine amidase
GAN19_RS02465	COG1783	phage Terminase large subunit
GAN19_RS02470	COG3728	DNA packaging
GAN19_RS02470	COG5484	DNA packaging
GAN19_RS02490	COG0756	dUTP diphosphatase activity
GAN19_RS02545	COG1484	DNA-dependent DNA replication
GAN19_RS02605	COG3422	double-strand break repair
GAN19_RS02615	COG3645	SOS response
GAN19_RS02615	COG3646	Phage regulatory protein
GAN19_RS02650	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
GAN19_RS02680	COG1960	acyl-CoA dehydrogenase activity
GAN19_RS02700	COG3942	CHAP domain
GAN19_RS02710	COG1757	Na H antiporter
GAN19_RS02720	COG3942	CHAP domain
GAN19_RS02725	COG2076	Multidrug Resistance protein
GAN19_RS02730	COG2076	Multidrug Resistance protein
GAN19_RS02735	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GAN19_RS02760	COG3383	formate dehydrogenase (NAD+) activity
GAN19_RS02765	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
GAN19_RS02780	COG1316	TRANSCRIPTIONal
GAN19_RS02805	COG1113	amino acid transport
GAN19_RS02830	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GAN19_RS02835	COG0346	lactoylglutathione lyase activity
GAN19_RS02845	COG0385	Bile acid
GAN19_RS02865	COG1473	amidohydrolase
GAN19_RS02870	COG0659	secondary active sulfate transmembrane transporter activity
GAN19_RS02875	COG1228	amidohydrolase
GAN19_RS02880	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
GAN19_RS02885	COG3314	Sporulation integral membrane protein YlbJ
GAN19_RS02890	COG0583	DNA-binding transcription factor activity
GAN19_RS02895	COG1266	CAAX protease self-immunity
GAN19_RS02905	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
GAN19_RS02910	COG2258	MOSC domain
GAN19_RS02915	COG2017	converts alpha-aldose to the beta-anomer
GAN19_RS02920	COG1742	UPF0060 membrane protein
GAN19_RS02925	COG1668	transmembrane transport
GAN19_RS02930	COG4152	abc transporter atp-binding protein
GAN19_RS02935	COG3152	Membrane
GAN19_RS02940	COG2094	Belongs to the DNA glycosylase MPG family
GAN19_RS02945	COG1757	Na H antiporter
GAN19_RS02965	COG3250	beta-galactosidase activity
GAN19_RS02970	COG2207	Transcriptional regulator
GAN19_RS02975	COG0786	glutamate:sodium symporter activity
GAN19_RS03000	COG0523	cobalamin synthesis protein
GAN19_RS03005	COG1304	FMN binding
GAN19_RS03025	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GAN19_RS03035	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
GAN19_RS03045	COG3344	reverse transcriptase
GAN19_RS03075	COG0577	efflux transmembrane transporter activity
GAN19_RS03090	COG0579	oxidoreductase
GAN19_RS03095	COG0438	transferase activity, transferring glycosyl groups
GAN19_RS03100	COG1620	l-lactate permease
GAN19_RS03130	COG0604	alcohol dehydrogenase
GAN19_RS03135	COG2814	Major facilitator Superfamily
GAN19_RS03140	COG0492	ferredoxin-NADP+ reductase activity
GAN19_RS03160	COG1283	sodium-dependent phosphate transmembrane transporter activity
GAN19_RS03175	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GAN19_RS03175	COG1263	PTS System
GAN19_RS03185	COG2807	transmembrane transport
GAN19_RS03195	COG0697	spore germination
GAN19_RS03200	COG1363	Peptidase, m42
GAN19_RS03205	COG0039	L-malate dehydrogenase activity
GAN19_RS03215	COG4187	Peptidase family M20/M25/M40
GAN19_RS03220	COG3344	reverse transcriptase
GAN19_RS03225	COG2223	nitrite transmembrane transporter activity
GAN19_RS03235	COG2197	response regulator
GAN19_RS03240	COG4585	Histidine kinase
GAN19_RS03250	COG2181	nitrate reductase activity
GAN19_RS03260	COG1140	nitrate reductase beta subunit
GAN19_RS03265	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
GAN19_RS03275	COG0737	Belongs to the 5'-nucleotidase family
GAN19_RS03280	COG1648	precorrin-2 dehydrogenase activity
GAN19_RS03280	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
GAN19_RS03285	COG2146	nitrite reductase [NAD(P)H] activity
GAN19_RS03290	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GAN19_RS03295	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
GAN19_RS03295	COG1648	precorrin-2 dehydrogenase activity
GAN19_RS03305	COG0454	-acetyltransferase
GAN19_RS03310	COG2116	formate transmembrane transporter activity
GAN19_RS03315	COG0471	metal ion transport
GAN19_RS03365	COG1760	l-serine dehydratase
GAN19_RS03370	COG1760	l-serine dehydratase
GAN19_RS03385	COG0702	epimerase
GAN19_RS03390	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
GAN19_RS03410	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
GAN19_RS03420	COG1929	Belongs to the glycerate kinase type-1 family
GAN19_RS03425	COG3764	Sortase (surface protein transpeptidase)
GAN19_RS03430	COG2271	Major facilitator Superfamily
GAN19_RS03435	COG2814	Major facilitator Superfamily
GAN19_RS03440	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
GAN19_RS03445	COG1115	amino acid carrier protein
GAN19_RS03455	COG0346	lactoylglutathione lyase activity
GAN19_RS03480	COG1674	ftsk spoiiie
GAN19_RS03490	COG2946	Replication initiation factor
GAN19_RS03520	COG0791	NLP P60 protein
GAN19_RS03520	COG0741	lytic transglycosylase activity
GAN19_RS03590	COG1132	(ABC) transporter
GAN19_RS03595	COG1132	(ABC) transporter
GAN19_RS03600	COG0247	lactate metabolic process
GAN19_RS03605	COG0277	FAD linked oxidase domain protein
GAN19_RS03625	COG0159	tryptophan synthase activity
GAN19_RS03630	COG0133	tryptophan synthase activity
GAN19_RS03640	COG0134	indole-3-glycerol-phosphate synthase activity
GAN19_RS03650	COG0512	Glutamine amidotransferase of anthranilate synthase
GAN19_RS03655	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
GAN19_RS03660	COG3961	Belongs to the TPP enzyme family
GAN19_RS03665	COG2855	membrane
GAN19_RS03670	COG3835	regulator
GAN19_RS03685	COG1028	Short-chain dehydrogenase reductase Sdr
GAN19_RS03725	COG2357	RelA SpoT domain protein
GAN19_RS03730	COG0778	Nitroreductase
GAN19_RS03735	COG1846	Transcriptional regulator
GAN19_RS03750	COG1346	cytolysis
GAN19_RS03760	COG0583	DNA-binding transcription factor activity
GAN19_RS03790	COG1141	Ferredoxin
GAN19_RS03800	COG0523	cobalamin synthesis protein
GAN19_RS03805	COG0717	Belongs to the dCTP deaminase family
GAN19_RS03810	COG0804	urea catabolic process
GAN19_RS03815	COG0832	Belongs to the urease beta subunit family
GAN19_RS03825	COG4413	Urea transporter
GAN19_RS03845	COG0577	efflux transmembrane transporter activity
GAN19_RS03850	COG1136	(ABC) transporter
GAN19_RS03875	COG3001	Fructosamine kinase
GAN19_RS03880	COG0778	Nitroreductase
GAN19_RS03885	COG3181	Tripartite tricarboxylate transporter family receptor
GAN19_RS03900	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
GAN19_RS03905	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GAN19_RS03910	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
GAN19_RS03910	COG0463	Glycosyl transferase, family 2
GAN19_RS03935	COG0747	negative chemotaxis
GAN19_RS03940	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
GAN19_RS03945	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
GAN19_RS03960	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
GAN19_RS03970	COG1705	Flagellar rod assembly protein muramidase FlgJ
GAN19_RS03970	COG3942	CHAP domain
GAN19_RS03980	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GAN19_RS03980	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GAN19_RS03980	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GAN19_RS03985	COG0789	Transcriptional regulator
GAN19_RS03990	COG0596	Alpha beta hydrolase
GAN19_RS04005	COG1012	belongs to the aldehyde dehydrogenase family
GAN19_RS04010	COG2824	Alkylphosphonate utilization operon protein PhnA
GAN19_RS04015	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
GAN19_RS04020	COG1461	Dihydroxyacetone kinase
GAN19_RS04025	COG2376	Dihydroxyacetone kinase
GAN19_RS04060	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
GAN19_RS04065	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
GAN19_RS04070	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
GAN19_RS04075	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
GAN19_RS04090	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
GAN19_RS04095	COG0107	imidazoleglycerol-phosphate synthase activity
GAN19_RS04110	COG0156	8-amino-7-oxononanoate synthase activity
GAN19_RS04120	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
GAN19_RS04125	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
GAN19_RS04130	COG1012	belongs to the aldehyde dehydrogenase family
GAN19_RS04135	COG1510	regulation of RNA biosynthetic process
GAN19_RS04155	COG0494	nUDIX hydrolase
GAN19_RS04160	COG1785	Belongs to the alkaline phosphatase family
GAN19_RS04175	COG1396	sequence-specific DNA binding
GAN19_RS04180	COG2807	transmembrane transport
GAN19_RS04185	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
GAN19_RS04190	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
GAN19_RS04205	COG1957	nucleoside hydrolase
GAN19_RS04210	COG3250	beta-galactosidase activity
GAN19_RS04215	COG2211	Major facilitator Superfamily
GAN19_RS04220	COG0477	Major facilitator Superfamily
GAN19_RS04225	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
GAN19_RS04230	COG1210	Utp--glucose-1-phosphate uridylyltransferase
GAN19_RS04240	COG2972	Histidine kinase
GAN19_RS04245	COG2207	Transcriptional regulator
GAN19_RS04245	COG4753	response regulator
GAN19_RS04270	COG3443	Belongs to the bacterial solute-binding protein 9 family
GAN19_RS04270	COG0803	Belongs to the bacterial solute-binding protein 9 family
GAN19_RS04280	COG1942	4-Oxalocrotonate Tautomerase
GAN19_RS04285	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GAN19_RS04305	COG1328	CTP reductase activity
GAN19_RS04315	COG3037	sugar-specific permease SgaT UlaA
GAN19_RS04325	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GAN19_RS04330	COG3711	transcriptional antiterminator
GAN19_RS04360	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GAN19_RS04365	COG1609	Transcriptional regulator
GAN19_RS04385	COG1116	anion transmembrane transporter activity
GAN19_RS04395	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GAN19_RS04405	COG2814	Major facilitator Superfamily
GAN19_RS04415	COG0318	PFAM AMP-dependent synthetase and ligase
GAN19_RS04430	COG0183	Belongs to the thiolase family
GAN19_RS04435	COG0438	transferase activity, transferring glycosyl groups
GAN19_RS04455	COG1073	alpha beta
GAN19_RS04475	COG0579	oxidoreductase
GAN19_RS04500	COG1755	Isoprenylcysteine carboxyl methyltransferase
GAN19_RS04510	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GAN19_RS04520	COG1136	(ABC) transporter
GAN19_RS04545	COG0436	Aminotransferase
GAN19_RS04555	COG0783	Belongs to the Dps family
GAN19_RS04565	COG0753	catalase activity
GAN19_RS04570	COG2318	DinB family
GAN19_RS04585	COG0076	glutamate decarboxylase activity
GAN19_RS04600	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
GAN19_RS04645	COG0156	8-amino-7-oxononanoate synthase activity
GAN19_RS04650	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
GAN19_RS04655	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
GAN19_RS04660	COG1620	l-lactate permease
GAN19_RS04675	COG1063	alcohol dehydrogenase
GAN19_RS04695	COG3314	Sporulation integral membrane protein YlbJ
GAN19_RS04715	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
GAN19_RS04725	COG3716	PTS system mannose fructose sorbose family IID component
GAN19_RS04730	COG3715	PTS system
GAN19_RS04735	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GAN19_RS04735	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
GAN19_RS04750	COG1105	Belongs to the carbohydrate kinase PfkB family
GAN19_RS04755	COG2222	sugar isomerase
GAN19_RS04760	COG2188	Transcriptional regulator
GAN19_RS04765	COG0366	Alpha amylase catalytic
GAN19_RS04775	COG1131	(ABC) transporter
GAN19_RS04810	COG0346	lactoylglutathione lyase activity
GAN19_RS04820	COG0490	domain, Protein
GAN19_RS04825	COG0475	glutathione-regulated potassium exporter activity
GAN19_RS04830	COG3842	ATPase activity
GAN19_RS04840	COG1175	transmembrane transport
GAN19_RS04845	COG3833	ABC-type maltose transport systems, permease component
GAN19_RS04855	COG0366	Alpha amylase catalytic
GAN19_RS04865	COG0673	inositol 2-dehydrogenase activity
GAN19_RS04875	COG1609	Transcriptional regulator
GAN19_RS04895	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
GAN19_RS04895	COG3583	domain protein
GAN19_RS04895	COG4932	domain protein
GAN19_RS04900	COG0431	NADPH-dependent FMN reductase
GAN19_RS04920	COG1131	(ABC) transporter
GAN19_RS04925	COG0842	Transport permease protein
GAN19_RS04930	COG2203	Gaf domain
GAN19_RS04930	COG4585	Histidine kinase
GAN19_RS04935	COG2197	response regulator
GAN19_RS04950	COG2235	arginine
GAN19_RS04970	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GAN19_RS04975	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
GAN19_RS04985	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GAN19_RS04990	COG3177	Filamentation induced by cAMP protein fic
GAN19_RS05005	COG2130	NADP-dependent
GAN19_RS05010	COG0702	epimerase
GAN19_RS05025	COG0415	Belongs to the DNA photolyase family
GAN19_RS05035	COG2723	6-phospho-beta-galactosidase activity
GAN19_RS05040	COG2188	Transcriptional regulator
GAN19_RS05055	COG3655	Transcriptional regulator
GAN19_RS05070	COG2217	Heavy metal translocating P-type atpase
GAN19_RS05075	COG0531	amino acid
GAN19_RS05095	COG2311	Membrane
GAN19_RS05110	COG2132	Multicopper oxidase
GAN19_RS05120	COG0745	RESPONSE REGULATOR receiver
GAN19_RS05125	COG5002	protein histidine kinase activity
GAN19_RS05130	COG1388	LysM domain
GAN19_RS05135	COG3682	Transcriptional regulator
GAN19_RS05150	COG0785	Cytochrome C biogenesis protein
GAN19_RS05180	COG0730	response to heat
GAN19_RS05185	COG1937	Protein conserved in bacteria
GAN19_RS05190	COG2210	Belongs to the sulfur carrier protein TusA family
GAN19_RS05195	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GAN19_RS05205	COG1846	Transcriptional regulator
GAN19_RS05205	COG1940	carbohydrate kinase activity
GAN19_RS05230	COG2030	dehydratase
GAN19_RS05235	COG0584	glycerophosphoryl diester phosphodiesterase
GAN19_RS05245	COG3425	synthase
GAN19_RS05255	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
GAN19_RS05260	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
GAN19_RS05270	COG4863	YycH protein
GAN19_RS05275	COG5002	protein histidine kinase activity
GAN19_RS05280	COG0745	RESPONSE REGULATOR receiver
GAN19_RS05300	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GAN19_RS05305	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
GAN19_RS05310	COG0305	Participates in initiation and elongation during chromosome replication
GAN19_RS05320	COG0359	binds to the 23S rRNA
GAN19_RS05325	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
GAN19_RS05330	COG4241	membrane
GAN19_RS05335	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
GAN19_RS05345	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
GAN19_RS05355	COG2986	histidine ammonia-lyase
GAN19_RS05360	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
GAN19_RS05370	COG0187	DNA topoisomerase II activity
GAN19_RS05375	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
GAN19_RS05380	COG2501	S4 domain
GAN19_RS05385	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
GAN19_RS05385	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
GAN19_RS05390	COG0592	DNA-directed DNA polymerase activity
GAN19_RS05395	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
GAN19_RS05405	COG0594	ribonuclease P activity
GAN19_RS05410	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
GAN19_RS05415	COG0445	tRNA wobble uridine modification
GAN19_RS05420	COG0357	Ribosomal RNA small subunit methyltransferase G
GAN19_RS05445	COG0400	carboxylic ester hydrolase activity
GAN19_RS05450	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GAN19_RS05455	COG0346	lactoylglutathione lyase activity
GAN19_RS05460	COG1846	Transcriptional regulator
GAN19_RS05465	COG2388	GCN5-related N-acetyl-transferase
GAN19_RS05475	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
GAN19_RS05480	COG0830	nickel cation binding
GAN19_RS05490	COG0829	nickel cation binding
GAN19_RS05500	COG0646	methionine synthase
GAN19_RS05500	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
GAN19_RS05505	COG0626	cystathionine gamma-synthase activity
GAN19_RS05510	COG0626	cystathionine gamma-synthase activity
GAN19_RS05515	COG1475	DNA binding
GAN19_RS05520	COG0668	transmembrane transport
GAN19_RS05525	COG4481	Protein conserved in bacteria
GAN19_RS05530	COG0012	GTP binding
GAN19_RS05535	COG1131	(ABC) transporter
GAN19_RS05540	COG1668	transmembrane transport
GAN19_RS05550	COG0360	Binds together with S18 to 16S ribosomal RNA
GAN19_RS05560	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
GAN19_RS05565	COG0662	Cupin 2, conserved barrel domain protein
GAN19_RS05565	COG2207	Transcriptional regulator
GAN19_RS05575	COG1175	transmembrane transport
GAN19_RS05580	COG0395	ABC-type sugar transport system, permease component
GAN19_RS05585	COG0673	inositol 2-dehydrogenase activity
GAN19_RS05590	COG3842	ATPase activity
GAN19_RS05595	COG0753	catalase activity
GAN19_RS05600	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
GAN19_RS05605	COG1464	Belongs to the NlpA lipoprotein family
GAN19_RS05610	COG2011	ABC-type metal ion transport system permease component
GAN19_RS05615	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
GAN19_RS05625	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
GAN19_RS05640	COG0450	alkyl hydroperoxide reductase
GAN19_RS05645	COG0778	Nitroreductase
GAN19_RS05670	COG1823	symporter activity
GAN19_RS05675	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GAN19_RS05680	COG5183	chlorophyll binding
GAN19_RS05695	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GAN19_RS05700	COG2233	PERMEase
GAN19_RS05705	COG0516	GMP reductase activity
GAN19_RS05705	COG0517	IMP dehydrogenase activity
GAN19_RS05710	COG0519	Catalyzes the synthesis of GMP from XMP
GAN19_RS05710	COG0518	GMP synthase (glutamine-hydrolyzing) activity
GAN19_RS05745	COG1525	nuclease
GAN19_RS05765	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
GAN19_RS05790	COG0747	negative chemotaxis
GAN19_RS05795	COG0601	transmembrane transport
GAN19_RS05800	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GAN19_RS05805	COG0444	Belongs to the ABC transporter superfamily
GAN19_RS05810	COG1124	(ABC) transporter
GAN19_RS05825	COG2814	Major facilitator Superfamily
GAN19_RS05830	COG0730	response to heat
GAN19_RS05835	COG1937	Protein conserved in bacteria
GAN19_RS05840	COG2210	Belongs to the sulfur carrier protein TusA family
GAN19_RS05860	COG1263	PTS System
GAN19_RS05860	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GAN19_RS05865	COG1486	melibiose metabolic process
GAN19_RS05875	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
GAN19_RS05910	COG3682	Transcriptional regulator
GAN19_RS05930	COG3344	reverse transcriptase
GAN19_RS05945	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GAN19_RS05945	COG0574	Belongs to the PEP-utilizing enzyme family
GAN19_RS05950	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
GAN19_RS05965	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
GAN19_RS05970	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
GAN19_RS05980	COG2205	protein histidine kinase activity
GAN19_RS05985	COG0745	RESPONSE REGULATOR receiver
GAN19_RS05995	COG0733	neurotransmitter:sodium symporter activity
GAN19_RS06000	COG2272	Belongs to the type-B carboxylesterase lipase family
GAN19_RS06005	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
GAN19_RS06010	COG0626	cystathionine gamma-synthase activity
GAN19_RS06015	COG3344	reverse transcriptase
GAN19_RS06040	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
GAN19_RS06055	COG0583	DNA-binding transcription factor activity
GAN19_RS06060	COG0070	glutamate synthase
GAN19_RS06060	COG0069	glutamate synthase activity
GAN19_RS06060	COG0067	glutamate synthase
GAN19_RS06065	COG0493	'glutamate synthase
GAN19_RS06075	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GAN19_RS06075	COG1263	PTS System
GAN19_RS06080	COG0366	Alpha amylase catalytic
GAN19_RS06085	COG2188	Transcriptional regulator
GAN19_RS06095	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
GAN19_RS06100	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
GAN19_RS06105	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
GAN19_RS06110	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
GAN19_RS06135	COG1982	Orn Lys Arg decarboxylase major
GAN19_RS06140	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
GAN19_RS06145	COG3870	Protein conserved in bacteria
GAN19_RS06150	COG0470	DNA polymerase III
GAN19_RS06155	COG1774	PSP1 C-terminal conserved region
GAN19_RS06160	COG4467	Involved in initiation control of chromosome replication
GAN19_RS06165	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
GAN19_RS06170	COG2827	Endonuclease containing a URI domain
GAN19_RS06175	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
GAN19_RS06185	COG0084	hydrolase, TatD family'
GAN19_RS06190	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
GAN19_RS06200	COG4466	Protein conserved in bacteria
GAN19_RS06205	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
GAN19_RS06210	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GAN19_RS06215	COG0251	oxidation-reduction process
GAN19_RS06220	COG2088	sporulation resulting in formation of a cellular spore
GAN19_RS06225	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
GAN19_RS06230	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GAN19_RS06240	COG0193	aminoacyl-tRNA hydrolase activity
GAN19_RS06245	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
GAN19_RS06250	COG2244	polysaccharide biosynthetic process
GAN19_RS06255	COG3956	TIGRFAM MazG family protein
GAN19_RS06260	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
GAN19_RS06270	COG1098	S1 RNA binding domain
GAN19_RS06285	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GAN19_RS06290	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
GAN19_RS06300	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
GAN19_RS06310	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
GAN19_RS06315	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GAN19_RS06390	COG1289	transmembrane transporter activity
GAN19_RS06395	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GAN19_RS06400	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
GAN19_RS06405	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
GAN19_RS06415	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GAN19_RS06425	COG3880	PFAM UvrB UvrC protein
GAN19_RS06430	COG3869	Catalyzes the specific phosphorylation of arginine residues in
GAN19_RS06435	COG0542	response to heat
GAN19_RS06470	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
GAN19_RS06475	COG4956	integral membrane protein (PIN domain superfamily)
GAN19_RS06480	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
GAN19_RS06490	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GAN19_RS06495	COG1045	serine acetyltransferase
GAN19_RS06500	COG0215	cysteine-tRNA ligase activity
GAN19_RS06505	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
GAN19_RS06525	COG0267	Belongs to the bacterial ribosomal protein bL33 family
GAN19_RS06530	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
GAN19_RS06535	COG0250	Participates in transcription elongation, termination and antitermination
GAN19_RS06540	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
GAN19_RS06545	COG0081	regulation of translation
GAN19_RS06550	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
GAN19_RS06560	COG2813	Specifically methylates the guanine in position
GAN19_RS06565	COG0085	RNA polymerase activity
GAN19_RS06570	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GAN19_RS06580	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
GAN19_RS06585	COG0049	tRNA binding
GAN19_RS06590	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
GAN19_RS06595	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
GAN19_RS06600	COG3527	Alpha-acetolactate decarboxylase
GAN19_RS06605	COG1473	amidohydrolase
GAN19_RS06615	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GAN19_RS06645	COG0546	phosphoglycolate phosphatase activity
GAN19_RS06650	COG1428	Deoxynucleoside kinase
GAN19_RS06655	COG1428	Deoxynucleoside kinase
GAN19_RS06665	COG0561	phosphatase activity
GAN19_RS06680	COG1136	(ABC) transporter
GAN19_RS06680	COG0577	efflux transmembrane transporter activity
GAN19_RS06730	COG1469	GTP cyclohydrolase I activity
GAN19_RS06735	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
GAN19_RS06750	COG2190	(PTS) system
GAN19_RS06750	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GAN19_RS06750	COG1263	PTS System
GAN19_RS06765	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
GAN19_RS06775	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GAN19_RS06780	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
GAN19_RS06785	COG0588	phosphoglycerate mutase activity
GAN19_RS06790	COG0318	PFAM AMP-dependent synthetase and ligase
GAN19_RS06795	COG0183	Belongs to the thiolase family
GAN19_RS06825	COG2363	Small membrane protein
GAN19_RS06850	COG1566	PFAM secretion protein HlyD family protein
GAN19_RS06855	COG2814	Major facilitator Superfamily
GAN19_RS06865	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
GAN19_RS06870	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GAN19_RS06875	COG0095	Lipoate-protein ligase
GAN19_RS06880	COG0280	phosphate acetyltransferase
GAN19_RS06910	COG0471	metal ion transport
GAN19_RS06970	COG4844	belongs to the
GAN19_RS06980	COG1078	dGTPase activity
GAN19_RS06995	COG0018	arginyl-trna synthetase
GAN19_RS07000	COG0805	protein transport
GAN19_RS07005	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GAN19_RS07010	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GAN19_RS07015	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GAN19_RS07020	COG0546	phosphoglycolate phosphatase activity
GAN19_RS07070	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
GAN19_RS07070	COG2111	Na H antiporter
GAN19_RS07075	COG2111	Na H antiporter
GAN19_RS07080	COG1006	Multisubunit Na H antiporter MnhC subunit
GAN19_RS07090	COG1863	multisubunit Na H antiporter MnhE subunit
GAN19_RS07095	COG2212	antiporter activity
GAN19_RS07100	COG1320	monovalent cation:proton antiporter activity
GAN19_RS07105	COG0803	Belongs to the bacterial solute-binding protein 9 family
GAN19_RS07110	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GAN19_RS07115	COG1121	(ABC) transporter
GAN19_RS07125	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GAN19_RS07130	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GAN19_RS07135	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GAN19_RS07145	COG2423	ornithine cyclodeaminase activity
GAN19_RS07150	COG4264	IucA IucC family
GAN19_RS07155	COG2814	Major facilitator Superfamily
GAN19_RS07160	COG4264	IucA IucC family
GAN19_RS07165	COG4264	IucA IucC family
GAN19_RS07175	COG0019	diaminopimelate decarboxylase activity
GAN19_RS07180	COG1475	DNA binding
GAN19_RS07190	COG0110	maltose O-acetyltransferase activity
GAN19_RS07195	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
GAN19_RS07205	COG1682	transport, permease protein
GAN19_RS07210	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
GAN19_RS07215	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
GAN19_RS07235	COG1686	Belongs to the peptidase S11 family
GAN19_RS07240	COG1132	(ABC) transporter
GAN19_RS07260	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GAN19_RS07265	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GAN19_RS07270	COG1120	ATPase activity
GAN19_RS07275	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GAN19_RS07280	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GAN19_RS07290	COG0477	Major facilitator Superfamily
GAN19_RS07295	COG3949	Membrane
GAN19_RS07305	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GAN19_RS07310	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GAN19_RS07315	COG0745	RESPONSE REGULATOR receiver
GAN19_RS07325	COG1136	(ABC) transporter
GAN19_RS07330	COG0577	efflux transmembrane transporter activity
GAN19_RS07335	COG1392	Phosphate transport regulator
GAN19_RS07340	COG0306	phosphate transporter
GAN19_RS07345	COG3942	CHAP domain
GAN19_RS07345	COG1388	LysM domain
GAN19_RS07355	COG0352	thiamine-phosphate diphosphorylase activity
GAN19_RS07365	COG2022	thiamine diphosphate biosynthetic process
GAN19_RS07370	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
GAN19_RS07375	COG0217	transcriptional regulatory protein
GAN19_RS07390	COG0583	DNA-binding transcription factor activity
GAN19_RS07395	COG2814	Major facilitator Superfamily
GAN19_RS07400	COG2839	Protein conserved in bacteria
GAN19_RS07430	COG1611	Belongs to the LOG family
GAN19_RS07435	COG1671	Belongs to the UPF0178 family
GAN19_RS07445	COG1968	undecaprenyl-diphosphatase activity
GAN19_RS07450	COG4988	ABC transporter
GAN19_RS07455	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
GAN19_RS07470	COG0523	cobalamin synthesis protein
GAN19_RS07475	COG4989	oxidoreductase activity
GAN19_RS07490	COG0039	L-malate dehydrogenase activity
GAN19_RS07515	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
GAN19_RS07520	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
GAN19_RS07540	COG1349	DNA-binding transcription factor activity
GAN19_RS07545	COG1105	Belongs to the carbohydrate kinase PfkB family
GAN19_RS07550	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GAN19_RS07550	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GAN19_RS07550	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GAN19_RS07555	COG1253	flavin adenine dinucleotide binding
GAN19_RS07560	COG0463	Glycosyl transferase, family 2
GAN19_RS07575	COG0602	queuosine metabolic process
GAN19_RS07580	COG0720	synthase
GAN19_RS07590	COG0512	Glutamine amidotransferase of anthranilate synthase
GAN19_RS07610	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
GAN19_RS07620	COG1368	sulfuric ester hydrolase activity
GAN19_RS07630	COG0463	Glycosyl transferase, family 2
GAN19_RS07645	COG2274	protein secretion by the type I secretion system
GAN19_RS07655	COG0488	(ABC) transporter
GAN19_RS07660	COG0514	ATP-dependent DNA helicase (RecQ)
GAN19_RS07665	COG1125	glycine betaine transport
GAN19_RS07665	COG0517	IMP dehydrogenase activity
GAN19_RS07670	COG1174	glycine betaine transport
GAN19_RS07675	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
GAN19_RS07690	COG3104	oligopeptide transport
GAN19_RS07695	COG3104	oligopeptide transport
GAN19_RS07730	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GAN19_RS07735	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GAN19_RS07745	COG0812	UDP-N-acetylmuramate dehydrogenase activity
GAN19_RS07760	COG3118	belongs to the thioredoxin family
GAN19_RS07765	COG1929	Belongs to the glycerate kinase type-1 family
GAN19_RS07770	COG2195	Cleaves the N-terminal amino acid of tripeptides
GAN19_RS07790	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GAN19_RS07795	COG1739	Uncharacterized protein family UPF0029
GAN19_RS07805	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
GAN19_RS07820	COG0653	protein targeting
GAN19_RS07855	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
GAN19_RS07860	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
GAN19_RS07865	COG0110	maltose O-acetyltransferase activity
GAN19_RS07880	COG1660	Displays ATPase and GTPase activities
GAN19_RS07885	COG0391	Required for morphogenesis under gluconeogenic growth conditions
GAN19_RS07890	COG1481	regulation of sporulation
GAN19_RS07905	COG0740	serine-type endopeptidase activity
GAN19_RS07915	COG1090	epimerase
GAN19_RS07940	COG0126	phosphoglycerate kinase activity
GAN19_RS07945	COG0149	triose-phosphate isomerase activity
GAN19_RS07950	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
GAN19_RS07955	COG0148	phosphopyruvate hydratase activity
GAN19_RS07975	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
GAN19_RS07980	COG1647	Serine aminopeptidase, S33
GAN19_RS07985	COG0557	exoribonuclease II activity
GAN19_RS08015	COG0346	lactoylglutathione lyase activity
GAN19_RS08035	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
GAN19_RS08050	COG1764	response to oxidative stress
GAN19_RS08060	COG0710	3-dehydroquinate dehydratase activity
GAN19_RS08070	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GAN19_RS08075	COG1393	Belongs to the ArsC family
GAN19_RS08085	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
GAN19_RS08090	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GAN19_RS08100	COG2011	ABC-type metal ion transport system permease component
GAN19_RS08105	COG1464	Belongs to the NlpA lipoprotein family
GAN19_RS08110	COG1464	Belongs to the NlpA lipoprotein family
GAN19_RS08125	COG0396	ATPase activity
GAN19_RS08130	COG0719	Fe-S assembly protein
GAN19_RS08140	COG0822	iron-sulfur transferase activity
GAN19_RS08145	COG0719	Fe-S assembly protein
GAN19_RS08155	COG1253	flavin adenine dinucleotide binding
GAN19_RS08170	COG1801	Protein of unknown function DUF72
GAN19_RS08175	COG0730	response to heat
GAN19_RS08180	COG0737	Belongs to the 5'-nucleotidase family
GAN19_RS08185	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
GAN19_RS08190	COG4470	Protein conserved in bacteria
GAN19_RS08200	COG2445	Protein of unknown function DUF86
GAN19_RS08205	COG0647	UMP catabolic process
GAN19_RS08210	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GAN19_RS08215	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
GAN19_RS08220	COG4837	Protein of unknown function (DUF1462)
GAN19_RS08225	COG1252	NADH dehydrogenase
GAN19_RS08230	COG4844	belongs to the
GAN19_RS08235	COG0316	Belongs to the HesB IscA family
GAN19_RS08240	COG1252	NADH dehydrogenase
GAN19_RS08245	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
GAN19_RS08250	COG2056	Na+-H+ antiporter family
GAN19_RS08260	COG1320	monovalent cation:proton antiporter activity
GAN19_RS08265	COG2212	antiporter activity
GAN19_RS08270	COG1863	multisubunit Na H antiporter MnhE subunit
GAN19_RS08275	COG0651	ATP synthesis coupled electron transport
GAN19_RS08280	COG1006	Multisubunit Na H antiporter MnhC subunit
GAN19_RS08285	COG2111	Na H antiporter
GAN19_RS08290	COG2111	Na H antiporter
GAN19_RS08290	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
GAN19_RS08300	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GAN19_RS08320	COG1278	Cold shock
GAN19_RS08330	COG1098	S1 RNA binding domain
GAN19_RS08335	COG1012	belongs to the aldehyde dehydrogenase family
GAN19_RS08350	COG0584	glycerophosphoryl diester phosphodiesterase
GAN19_RS08360	COG0137	argininosuccinate synthase activity
GAN19_RS08365	COG0166	Belongs to the GPI family
GAN19_RS08380	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
GAN19_RS08390	COG0179	Fumarylacetoacetate (FAA) hydrolase
GAN19_RS08400	COG0446	pyridine nucleotide-disulphide oxidoreductase
GAN19_RS08405	COG0561	phosphatase activity
GAN19_RS08430	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
GAN19_RS08455	COG0601	transmembrane transport
GAN19_RS08460	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GAN19_RS08465	COG0444	Belongs to the ABC transporter superfamily
GAN19_RS08470	COG4608	Belongs to the ABC transporter superfamily
GAN19_RS08475	COG4166	transmembrane transport
GAN19_RS08480	COG0180	Tryptophanyl-tRNA synthetase
GAN19_RS08485	COG1393	Belongs to the ArsC family
GAN19_RS08510	COG1164	Oligoendopeptidase f
GAN19_RS08520	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
GAN19_RS08525	COG2346	COG2346, Truncated hemoglobins
GAN19_RS08540	COG2357	RelA SpoT domain protein
GAN19_RS08550	COG0564	pseudouridine synthase activity
GAN19_RS08555	COG2239	Acts as a magnesium transporter
GAN19_RS08560	COG0475	glutathione-regulated potassium exporter activity
GAN19_RS08560	COG0569	domain protein
GAN19_RS08570	COG0628	permease
GAN19_RS08575	COG1115	amino acid carrier protein
GAN19_RS08580	COG2382	esterase
GAN19_RS08585	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
GAN19_RS08615	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
GAN19_RS08650	COG3716	PTS system mannose fructose sorbose family IID component
GAN19_RS08655	COG3715	PTS system
GAN19_RS08665	COG2814	Major facilitator Superfamily
GAN19_RS08670	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
GAN19_RS08675	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
GAN19_RS08685	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
GAN19_RS08690	COG0861	Integral membrane protein TerC family
GAN19_RS08695	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GAN19_RS08700	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GAN19_RS08705	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
GAN19_RS08715	COG1696	Membrane protein involved in D-alanine export
GAN19_RS08720	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GAN19_RS08730	COG0737	Belongs to the 5'-nucleotidase family
GAN19_RS08735	COG4932	domain protein
GAN19_RS08735	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
GAN19_RS08735	COG3266	domain, Protein
GAN19_RS08745	COG3344	reverse transcriptase
GAN19_RS08815	COG4873	Protein conserved in bacteria
GAN19_RS08835	COG4619	ABC transporter
GAN19_RS08840	COG0390	transport system, permease component
GAN19_RS08845	COG1575	Belongs to the MenA family. Type 1 subfamily
GAN19_RS08850	COG1169	isochorismate synthase
GAN19_RS08855	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
GAN19_RS08865	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
GAN19_RS08870	COG0436	Aminotransferase
GAN19_RS08875	COG3594	Acyltransferase
GAN19_RS08900	COG1316	TRANSCRIPTIONal
GAN19_RS08905	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GAN19_RS08910	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
GAN19_RS08920	COG1215	transferase activity, transferring glycosyl groups
GAN19_RS08930	COG1682	transport, permease protein
GAN19_RS08940	COG1134	teichoic acid transport
GAN19_RS08955	COG3212	peptidase
GAN19_RS08965	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
GAN19_RS08970	COG1845	cytochrome c oxidase, subunit III
GAN19_RS08980	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
GAN19_RS08990	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GAN19_RS08990	COG1017	nitric oxide dioxygenase activity
GAN19_RS08995	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
GAN19_RS09000	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
GAN19_RS09005	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
GAN19_RS09010	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
GAN19_RS09015	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GAN19_RS09020	COG0047	phosphoribosylformylglycinamidine synthase activity
GAN19_RS09030	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
GAN19_RS09035	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
GAN19_RS09045	COG0138	bifunctional purine biosynthesis protein purh
GAN19_RS09050	COG0151	Belongs to the GarS family
GAN19_RS09060	COG4172	Belongs to the ABC transporter superfamily
GAN19_RS09075	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
GAN19_RS09085	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GAN19_RS09090	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GAN19_RS09095	COG1393	Belongs to the ArsC family
GAN19_RS09100	COG1271	oxidase subunit
GAN19_RS09105	COG1294	oxidase, subunit
GAN19_RS09110	COG0569	domain protein
GAN19_RS09135	COG0492	ferredoxin-NADP+ reductase activity
GAN19_RS09140	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
GAN19_RS09145	COG5503	Protein of unknown function (DUF1447)
GAN19_RS09185	COG4476	Belongs to the UPF0223 family
GAN19_RS09195	COG3842	ATPase activity
GAN19_RS09205	COG1177	transmembrane transport
GAN19_RS09210	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
GAN19_RS09225	COG4493	Belongs to the UPF0637 family
GAN19_RS09230	COG0483	inositol monophosphate 1-phosphatase activity
GAN19_RS09240	COG1217	gtp-binding protein TYPA
GAN19_RS09245	COG1902	pentaerythritol trinitrate reductase activity
GAN19_RS09250	COG4896	Protein conserved in bacteria
GAN19_RS09255	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
GAN19_RS09260	COG4838	Belongs to the UPF0358 family
GAN19_RS09265	COG0772	Belongs to the SEDS family
GAN19_RS09270	COG3344	reverse transcriptase
GAN19_RS09275	COG3344	reverse transcriptase
GAN19_RS09295	COG0109	protoheme IX farnesyltransferase activity
GAN19_RS09310	COG3679	Belongs to the UPF0342 family
GAN19_RS09315	COG0584	glycerophosphoryl diester phosphodiesterase
GAN19_RS09320	COG4471	UPF0298 protein
GAN19_RS09330	COG0742	ribosomal rna small subunit methyltransferase
GAN19_RS09350	COG0333	Belongs to the bacterial ribosomal protein bL32 family
GAN19_RS09355	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GAN19_RS09360	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
GAN19_RS09375	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GAN19_RS09390	COG1796	DNA polymerase
GAN19_RS09390	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
GAN19_RS09395	COG1193	negative regulation of DNA recombination
GAN19_RS09400	COG3118	belongs to the thioredoxin family
GAN19_RS09405	COG0322	excinuclease ABC activity
GAN19_RS09410	COG2009	succinate dehydrogenase
GAN19_RS09415	COG1053	succinate dehydrogenase
GAN19_RS09420	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
GAN19_RS09425	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
GAN19_RS09485	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GAN19_RS09500	COG1011	Hydrolase
GAN19_RS09505	COG0454	-acetyltransferase
GAN19_RS09510	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
GAN19_RS09515	COG2001	Belongs to the MraZ family
GAN19_RS09520	COG0275	rRNA processing
GAN19_RS09525	COG4839	cell division protein FtsL
GAN19_RS09530	COG0768	penicillin binding
GAN19_RS09540	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
GAN19_RS09550	COG0849	cell division
GAN19_RS09555	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
GAN19_RS09565	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
GAN19_RS09570	COG1799	cell septum assembly
GAN19_RS09575	COG0762	integral membrane protein
GAN19_RS09580	COG1869	D-ribose catabolic process
GAN19_RS09585	COG4975	Glucose uptake
GAN19_RS09595	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GAN19_RS09600	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GAN19_RS09610	COG4409	exo-alpha-(2->6)-sialidase activity
GAN19_RS09615	COG0673	inositol 2-dehydrogenase activity
GAN19_RS09625	COG3599	regulation of cell shape
GAN19_RS09630	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
GAN19_RS09635	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
GAN19_RS09640	COG0564	pseudouridine synthase activity
GAN19_RS09645	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
GAN19_RS09665	COG0505	Belongs to the CarA family
GAN19_RS09670	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
GAN19_RS09680	COG0167	dihydroorotate dehydrogenase activity
GAN19_RS09685	COG0284	orotidine-5'-phosphate decarboxylase activity
GAN19_RS09690	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
GAN19_RS09710	COG1758	RNA polymerase activity
GAN19_RS09715	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
GAN19_RS09720	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
GAN19_RS09725	COG0242	peptide deformylase activity
GAN19_RS09730	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
GAN19_RS09735	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GAN19_RS09735	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GAN19_RS09740	COG0820	rRNA (adenine-C2-)-methyltransferase activity
GAN19_RS09755	COG2124	cytochrome p450
GAN19_RS09760	COG1162	GTPase activity
GAN19_RS09765	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
GAN19_RS09780	COG1302	Protein conserved in bacteria
GAN19_RS09790	COG1760	l-serine dehydratase
GAN19_RS09795	COG1760	l-serine dehydratase
GAN19_RS09805	COG1349	DNA-binding transcription factor activity
GAN19_RS09810	COG0416	fatty acid biosynthetic process
GAN19_RS09825	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GAN19_RS09830	COG0571	ribonuclease III activity
GAN19_RS09835	COG1196	nuclear chromosome segregation
GAN19_RS09840	COG0552	protein localization to endoplasmic reticulum
GAN19_RS09845	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
GAN19_RS09850	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GAN19_RS09865	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
GAN19_RS09885	COG0228	four-way junction DNA binding
GAN19_RS09890	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
GAN19_RS09895	COG0336	Belongs to the RNA methyltransferase TrmD family
GAN19_RS09935	COG4485	Bacterial membrane protein, YfhO
GAN19_RS09950	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GAN19_RS09960	COG0045	succinate-CoA ligase (ADP-forming) activity
GAN19_RS09970	COG0758	DNA mediated transformation
GAN19_RS09975	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GAN19_RS09980	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
GAN19_RS09985	COG4974	Belongs to the 'phage' integrase family
GAN19_RS09990	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
GAN19_RS09995	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
GAN19_RS10000	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
GAN19_RS10005	COG0052	Belongs to the universal ribosomal protein uS2 family
GAN19_RS10010	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
GAN19_RS10015	COG0528	UMP kinase activity
GAN19_RS10020	COG0233	cytoplasmic translational termination
GAN19_RS10030	COG4589	Belongs to the CDS family
GAN19_RS10035	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
GAN19_RS10045	COG0442	prolyl-tRNA aminoacylation
GAN19_RS10055	COG0779	Required for maturation of 30S ribosomal subunits
GAN19_RS10060	COG0195	Participates in both transcription termination and antitermination
GAN19_RS10065	COG2740	Nucleic-acid-binding protein implicated in transcription termination
GAN19_RS10070	COG1358	cellular component organization or biogenesis
GAN19_RS10075	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
GAN19_RS10085	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
GAN19_RS10090	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
GAN19_RS10095	COG0196	riboflavin kinase activity
GAN19_RS10105	COG1185	polyribonucleotide nucleotidyltransferase activity
GAN19_RS10120	COG2188	Transcriptional regulator
GAN19_RS10125	COG0612	Peptidase, M16
GAN19_RS10130	COG0612	Peptidase, M16
GAN19_RS10135	COG0300	oxidoreductase activity
GAN19_RS10155	COG1058	Belongs to the CinA family
GAN19_RS10155	COG1546	Belongs to the CinA family
GAN19_RS10160	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
GAN19_RS10165	COG1418	mRNA catabolic process
GAN19_RS10185	COG1692	metallophosphoesterase
GAN19_RS10190	COG0674	pyruvate-flavodoxin oxidoreductase activity
GAN19_RS10190	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
GAN19_RS10195	COG1013	pyruvate-flavodoxin oxidoreductase activity
GAN19_RS10205	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GAN19_RS10225	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
GAN19_RS10230	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
GAN19_RS10235	COG1619	proteins homologs of microcin C7 resistance protein MccF
GAN19_RS10240	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
GAN19_RS10250	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
GAN19_RS10255	COG1923	regulation of RNA biosynthetic process
GAN19_RS10260	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
GAN19_RS10265	COG2267	carboxylic ester hydrolase activity
GAN19_RS10270	COG0386	Belongs to the glutathione peroxidase family
GAN19_RS10275	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
GAN19_RS10280	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
GAN19_RS10285	COG0789	Transcriptional regulator
GAN19_RS10310	COG0584	glycerophosphoryl diester phosphodiesterase
GAN19_RS10340	COG1525	nuclease
GAN19_RS10360	COG0527	aspartate kinase activity
GAN19_RS10365	COG0460	homoserine dehydrogenase
GAN19_RS10370	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
GAN19_RS10375	COG0083	homoserine kinase activity
GAN19_RS10390	COG0833	amino acid
GAN19_RS10400	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
GAN19_RS10405	COG0516	GMP reductase activity
GAN19_RS10415	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
GAN19_RS10425	COG4224	UPF0291 protein
GAN19_RS10435	COG3763	UPF0154 protein
GAN19_RS10440	COG4846	Membrane protein involved in cytochrome C biogenesis
GAN19_RS10445	COG0420	3'-5' exonuclease activity
GAN19_RS10450	COG0419	ATPase involved in DNA repair
GAN19_RS10455	COG1970	mechanosensitive ion channel activity
GAN19_RS10460	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
GAN19_RS10470	COG0824	Thioesterase
GAN19_RS10475	COG4841	protein insertion into membrane
GAN19_RS10480	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
GAN19_RS10490	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GAN19_RS10495	COG1115	amino acid carrier protein
GAN19_RS10500	COG3711	transcriptional antiterminator
GAN19_RS10510	COG0628	permease
GAN19_RS10530	COG1942	4-Oxalocrotonate Tautomerase
GAN19_RS10540	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GAN19_RS10545	COG0287	Prephenate dehydrogenase
GAN19_RS10550	COG1363	Peptidase, m42
GAN19_RS10580	COG2996	Protein conserved in bacteria
GAN19_RS10585	COG0488	(ABC) transporter
GAN19_RS10590	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
GAN19_RS10595	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GAN19_RS10600	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
GAN19_RS10605	COG2171	N-acyltransferase activity
GAN19_RS10610	COG1473	amidohydrolase
GAN19_RS10630	COG1278	Cold shock
GAN19_RS10650	COG3853	Toxic anion resistance protein (TelA)
GAN19_RS10660	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
GAN19_RS10665	COG1114	Component of the transport system for branched-chain amino acids
GAN19_RS10670	COG4548	von Willebrand factor, type A
GAN19_RS10675	COG0714	Associated with various cellular activities
GAN19_RS10700	COG0567	Dehydrogenase, E1 component
GAN19_RS10705	COG5002	protein histidine kinase activity
GAN19_RS10715	COG0671	phosphoesterase, PA-phosphatase related
GAN19_RS10720	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
GAN19_RS10730	COG0793	Belongs to the peptidase S41A family
GAN19_RS10740	COG2190	(PTS) system
GAN19_RS10775	COG1413	lyase activity
GAN19_RS10785	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
GAN19_RS10795	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GAN19_RS10800	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
GAN19_RS10805	COG2962	Rard protein
GAN19_RS10810	COG0116	Belongs to the methyltransferase superfamily
GAN19_RS10820	COG3599	regulation of cell shape
GAN19_RS10825	COG4474	Belongs to the UPF0398 family
GAN19_RS10840	COG4499	WXG100 protein secretion system (Wss), protein YukC
GAN19_RS10840	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GAN19_RS10850	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
GAN19_RS10855	COG3935	DnaD domain protein
GAN19_RS10860	COG0017	Asparaginyl-tRNA synthetase
GAN19_RS10875	COG0617	tRNA 3'-terminal CCA addition
GAN19_RS10880	COG0438	transferase activity, transferring glycosyl groups
GAN19_RS10885	COG1694	Mazg nucleotide pyrophosphohydrolase
GAN19_RS10895	COG4347	Protein of unknown function (DUF1405)
GAN19_RS10900	COG5582	Belongs to the UPF0302 family
GAN19_RS10905	COG0457	Tetratricopeptide repeat
GAN19_RS10915	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
GAN19_RS10925	COG0105	UTP biosynthetic process
GAN19_RS10930	COG0142	geranyltranstransferase activity
GAN19_RS10950	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
GAN19_RS10955	COG1160	GTP binding
GAN19_RS10960	COG0539	negative regulation of cytoplasmic translation
GAN19_RS10970	COG0252	asparaginase activity
GAN19_RS10975	COG0492	ferredoxin-NADP+ reductase activity
GAN19_RS10985	COG0514	ATP-dependent DNA helicase (RecQ)
GAN19_RS10995	COG1141	Ferredoxin
GAN19_RS11010	COG0745	RESPONSE REGULATOR receiver
GAN19_RS11015	COG1187	pseudouridine synthase activity
GAN19_RS11020	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
GAN19_RS11025	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
GAN19_RS11040	COG0735	belongs to the Fur family
GAN19_RS11045	COG0494	nUDIX hydrolase
GAN19_RS11050	COG0667	Aldo Keto reductase
GAN19_RS11060	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GAN19_RS11065	COG1234	tRNA 3'-trailer cleavage
GAN19_RS11070	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
GAN19_RS11100	COG2195	Cleaves the N-terminal amino acid of tripeptides
GAN19_RS11110	COG4129	membrane
GAN19_RS11120	COG0508	dehydrogenase complex catalyzes the overall conversion of
GAN19_RS11125	COG0022	dehydrogenase e1 component
GAN19_RS11130	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
GAN19_RS11135	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GAN19_RS11140	COG3426	butyrate kinase activity
GAN19_RS11145	COG0280	phosphate acetyltransferase
GAN19_RS11150	COG0497	DNA recombination
GAN19_RS11155	COG1438	arginine binding
GAN19_RS11160	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
GAN19_RS11165	COG0142	geranyltranstransferase activity
GAN19_RS11170	COG1722	exodeoxyribonuclease VII activity
GAN19_RS11175	COG1570	exodeoxyribonuclease VII activity
GAN19_RS11185	COG1302	Protein conserved in bacteria
GAN19_RS11190	COG0439	Biotin carboxylase
GAN19_RS11195	COG0511	ligase activity, forming carbon-carbon bonds
GAN19_RS11200	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
GAN19_RS11205	COG0006	proline dipeptidase activity
GAN19_RS11220	COG0095	Lipoate-protein ligase
GAN19_RS11225	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GAN19_RS11230	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GAN19_RS11240	COG0404	The glycine cleavage system catalyzes the degradation of glycine
GAN19_RS11245	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
GAN19_RS11275	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GAN19_RS11280	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GAN19_RS11285	COG0011	TIGRFAM Protein of
GAN19_RS11290	COG1940	carbohydrate kinase activity
GAN19_RS11295	COG4483	Protein conserved in bacteria
GAN19_RS11300	COG0705	Rhomboid family
GAN19_RS11305	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
GAN19_RS11315	COG0704	Plays a role in the regulation of phosphate uptake
GAN19_RS11320	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
GAN19_RS11325	COG0581	inorganic phosphate transmembrane transporter activity
GAN19_RS11330	COG0573	inorganic phosphate transmembrane transporter activity
GAN19_RS11335	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
GAN19_RS11340	COG0768	penicillin binding
GAN19_RS11350	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
GAN19_RS11355	COG0735	belongs to the Fur family
GAN19_RS11360	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GAN19_RS11365	COG1121	(ABC) transporter
GAN19_RS11370	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
GAN19_RS11375	COG0513	Belongs to the DEAD box helicase family
GAN19_RS11380	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
GAN19_RS11385	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
GAN19_RS11390	COG2384	SAM-dependent methyltransferase
GAN19_RS11395	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GAN19_RS11400	COG0358	DNA primase activity
GAN19_RS11405	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
GAN19_RS11410	COG0517	IMP dehydrogenase activity
GAN19_RS11415	COG0423	glycine-tRNA ligase activity
GAN19_RS11420	COG1381	Involved in DNA repair and RecF pathway recombination
GAN19_RS11425	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
GAN19_RS11435	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
GAN19_RS11445	COG1702	phosphate starvation-inducible protein PhoH
GAN19_RS11455	COG4864	UPF0365 protein
GAN19_RS11460	COG1030	water channel activity
GAN19_RS11475	COG3344	reverse transcriptase
GAN19_RS11480	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GAN19_RS11485	COG1385	rRNA (uridine-N3-)-methyltransferase activity
GAN19_RS11490	COG2264	protein methyltransferase activity
GAN19_RS11495	COG0484	heat shock protein binding
GAN19_RS11515	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GAN19_RS11525	COG0268	Binds directly to 16S ribosomal RNA
GAN19_RS11530	COG1466	dna polymerase III delta subunit
GAN19_RS11535	COG2333	competence protein COMEC
GAN19_RS11535	COG0658	competence protein
GAN19_RS11540	COG2131	deaminase
GAN19_RS11545	COG1596	polysaccharide export
GAN19_RS11545	COG1555	photosystem II stabilization
GAN19_RS11550	COG2226	methyltransferase
GAN19_RS11555	COG0799	negative regulation of ribosome biogenesis
GAN19_RS11560	COG1713	HD superfamily hydrolase involved in NAD metabolism
GAN19_RS11570	COG1534	Rna-binding protein
GAN19_RS11575	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
GAN19_RS11580	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
GAN19_RS11585	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
GAN19_RS11590	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
GAN19_RS11595	COG1914	H( )-stimulated, divalent metal cation uptake system
GAN19_RS11600	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
GAN19_RS11605	COG0439	Biotin carboxylase
GAN19_RS11610	COG0511	ligase activity, forming carbon-carbon bonds
GAN19_RS11615	COG1984	allophanate hydrolase subunit 2
GAN19_RS11620	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
GAN19_RS11630	COG0572	uridine kinase
GAN19_RS11635	COG0826	peptidase U32
GAN19_RS11640	COG0826	peptidase U32
GAN19_RS11645	COG4122	O-methyltransferase activity
GAN19_RS11650	COG3906	Belongs to the UPF0473 family
GAN19_RS11655	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
GAN19_RS11660	COG4472	Bacterial protein of unknown function (DUF965)
GAN19_RS11665	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
GAN19_RS11670	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
GAN19_RS11680	COG0482	sulfurtransferase activity
GAN19_RS11685	COG1104	cysteine desulfurase activity
GAN19_RS11690	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GAN19_RS11705	COG1959	2 iron, 2 sulfur cluster binding
GAN19_RS11710	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
GAN19_RS11715	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
GAN19_RS11725	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
GAN19_RS11735	COG0860	N-Acetylmuramoyl-L-alanine amidase
GAN19_RS11740	COG1490	D-aminoacyl-tRNA deacylase activity
GAN19_RS11750	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GAN19_RS11755	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
GAN19_RS11755	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
GAN19_RS11760	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GAN19_RS11760	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GAN19_RS11765	COG1862	Preprotein translocase
GAN19_RS11775	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
GAN19_RS11780	COG2255	four-way junction helicase activity
GAN19_RS11785	COG0632	four-way junction helicase activity
GAN19_RS11795	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
GAN19_RS11805	COG2868	ribosomal protein
GAN19_RS11830	COG2003	Belongs to the UPF0758 family
GAN19_RS11840	COG0285	dihydrofolate synthase activity
GAN19_RS11845	COG0525	valine-tRNA ligase activity
GAN19_RS11850	COG2818	Glycosylase
GAN19_RS11860	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
GAN19_RS11875	COG0181	hydroxymethylbilane synthase activity
GAN19_RS11885	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
GAN19_RS11890	COG0218	Necessary for normal cell division and for the maintenance of normal septation
GAN19_RS11900	COG0544	peptidyl-prolyl cis-trans isomerase activity
GAN19_RS11915	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
GAN19_RS11920	COG0291	Belongs to the bacterial ribosomal protein bL35 family
GAN19_RS11925	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
GAN19_RS11930	COG0833	amino acid
GAN19_RS11940	COG1484	DNA-dependent DNA replication
GAN19_RS11945	COG3611	Membrane attachment protein
GAN19_RS11960	COG0237	dephospho-CoA kinase activity
GAN19_RS11970	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GAN19_RS11970	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GAN19_RS11975	COG5002	protein histidine kinase activity
GAN19_RS11980	COG0745	RESPONSE REGULATOR receiver
GAN19_RS11985	COG0538	isocitrate dehydrogenase activity
GAN19_RS11990	COG0372	Belongs to the citrate synthase family
GAN19_RS11995	COG0469	pyruvate kinase activity
GAN19_RS12000	COG0205	6-phosphofructokinase activity
GAN19_RS12005	COG0825	malonyl-CoA metabolic process
GAN19_RS12010	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
GAN19_RS12015	COG0281	malic enzyme
GAN19_RS12020	COG0587	DNA-directed DNA polymerase activity
GAN19_RS12025	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
GAN19_RS12030	COG4109	DRTGG domain
GAN19_RS12040	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
GAN19_RS12045	COG0006	proline dipeptidase activity
GAN19_RS12055	COG0686	Belongs to the AlaDH PNT family
GAN19_RS12060	COG0589	response to stress
GAN19_RS12065	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
GAN19_RS12070	COG0827	DNA restriction-modification system
GAN19_RS12075	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
GAN19_RS12080	COG1714	RDD family
GAN19_RS12085	COG0616	signal peptide processing
GAN19_RS12095	COG0301	tRNA thio-modification
GAN19_RS12100	COG1104	cysteine desulfurase activity
GAN19_RS12105	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
GAN19_RS12110	COG1956	GAF domain-containing protein
GAN19_RS12115	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
GAN19_RS12150	COG0456	acetyltransferase
GAN19_RS12190	COG1764	response to oxidative stress
GAN19_RS12195	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
GAN19_RS12200	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GAN19_RS12210	COG0204	Acyl-transferase
GAN19_RS12215	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GAN19_RS12225	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
GAN19_RS12230	COG2759	Belongs to the formate--tetrahydrofolate ligase family
GAN19_RS12235	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GAN19_RS12240	COG0454	-acetyltransferase
GAN19_RS12250	COG1609	Transcriptional regulator
GAN19_RS12255	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
GAN19_RS12255	COG1605	Chorismate mutase
GAN19_RS12265	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
GAN19_RS12270	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
GAN19_RS12275	COG1674	ftsk spoiiie
GAN19_RS12280	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GAN19_RS12285	COG4848	Belongs to the UPF0354 family
GAN19_RS12290	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GAN19_RS12295	COG1363	Peptidase, m42
GAN19_RS12305	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GAN19_RS12310	COG0220	tRNA (guanine-N7-)-methyltransferase activity
GAN19_RS12315	COG0510	thiamine kinase activity
GAN19_RS12320	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GAN19_RS12325	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GAN19_RS12335	COG1187	pseudouridine synthase activity
GAN19_RS12340	COG2244	polysaccharide biosynthetic process
GAN19_RS12345	COG2081	HI0933 family
GAN19_RS12350	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GAN19_RS12355	COG0495	leucyl-tRNA aminoacylation
GAN19_RS12360	COG2814	Major facilitator Superfamily
GAN19_RS12365	COG1242	4 iron, 4 sulfur cluster binding
GAN19_RS12370	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
GAN19_RS12380	COG0039	L-malate dehydrogenase activity
GAN19_RS12385	COG2267	carboxylic ester hydrolase activity
GAN19_RS12400	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
GAN19_RS12405	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GAN19_RS12405	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GAN19_RS12410	COG0307	riboflavin synthase, alpha
GAN19_RS12415	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GAN19_RS12415	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate