locus-tag	class	description
GAN20_RS00020	COG0228	four-way junction DNA binding
GAN20_RS00025	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
GAN20_RS00030	COG0336	Belongs to the RNA methyltransferase TrmD family
GAN20_RS00070	COG4485	Bacterial membrane protein, YfhO
GAN20_RS00085	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GAN20_RS00095	COG0045	succinate-CoA ligase (ADP-forming) activity
GAN20_RS00105	COG0758	DNA mediated transformation
GAN20_RS00110	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GAN20_RS00115	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
GAN20_RS00120	COG4974	Belongs to the 'phage' integrase family
GAN20_RS00125	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
GAN20_RS00130	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
GAN20_RS00135	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
GAN20_RS00140	COG0052	Belongs to the universal ribosomal protein uS2 family
GAN20_RS00145	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
GAN20_RS00150	COG0528	UMP kinase activity
GAN20_RS00155	COG0233	cytoplasmic translational termination
GAN20_RS00165	COG4589	Belongs to the CDS family
GAN20_RS00170	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
GAN20_RS00180	COG0442	prolyl-tRNA aminoacylation
GAN20_RS00190	COG0779	Required for maturation of 30S ribosomal subunits
GAN20_RS00195	COG0195	Participates in both transcription termination and antitermination
GAN20_RS00200	COG2740	Nucleic-acid-binding protein implicated in transcription termination
GAN20_RS00205	COG1358	cellular component organization or biogenesis
GAN20_RS00210	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
GAN20_RS00220	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
GAN20_RS00225	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
GAN20_RS00230	COG0196	riboflavin kinase activity
GAN20_RS00240	COG1185	polyribonucleotide nucleotidyltransferase activity
GAN20_RS00255	COG2188	Transcriptional regulator
GAN20_RS00260	COG0612	Peptidase, M16
GAN20_RS00265	COG0612	Peptidase, M16
GAN20_RS00270	COG0300	oxidoreductase activity
GAN20_RS00290	COG1058	Belongs to the CinA family
GAN20_RS00290	COG1546	Belongs to the CinA family
GAN20_RS00295	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
GAN20_RS00300	COG1418	mRNA catabolic process
GAN20_RS00320	COG1692	metallophosphoesterase
GAN20_RS00325	COG0674	pyruvate-flavodoxin oxidoreductase activity
GAN20_RS00325	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
GAN20_RS00330	COG1013	pyruvate-flavodoxin oxidoreductase activity
GAN20_RS00340	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GAN20_RS00360	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
GAN20_RS00365	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
GAN20_RS00370	COG1619	proteins homologs of microcin C7 resistance protein MccF
GAN20_RS00375	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
GAN20_RS00385	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
GAN20_RS00390	COG1923	regulation of RNA biosynthetic process
GAN20_RS00395	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
GAN20_RS00400	COG2267	carboxylic ester hydrolase activity
GAN20_RS00405	COG0386	Belongs to the glutathione peroxidase family
GAN20_RS00410	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
GAN20_RS00415	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
GAN20_RS00420	COG0789	Transcriptional regulator
GAN20_RS00445	COG0584	glycerophosphoryl diester phosphodiesterase
GAN20_RS00475	COG1525	nuclease
GAN20_RS00495	COG0527	aspartate kinase activity
GAN20_RS00500	COG0460	homoserine dehydrogenase
GAN20_RS00505	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
GAN20_RS00510	COG0083	homoserine kinase activity
GAN20_RS00525	COG0833	amino acid
GAN20_RS00535	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
GAN20_RS00540	COG0516	GMP reductase activity
GAN20_RS00550	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
GAN20_RS00560	COG4224	UPF0291 protein
GAN20_RS00570	COG3763	UPF0154 protein
GAN20_RS00575	COG4846	Membrane protein involved in cytochrome C biogenesis
GAN20_RS00580	COG0420	3'-5' exonuclease activity
GAN20_RS00585	COG0419	ATPase involved in DNA repair
GAN20_RS00590	COG1970	mechanosensitive ion channel activity
GAN20_RS00595	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
GAN20_RS00605	COG0824	Thioesterase
GAN20_RS00610	COG4841	protein insertion into membrane
GAN20_RS00615	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
GAN20_RS00625	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GAN20_RS00630	COG1115	amino acid carrier protein
GAN20_RS00635	COG3711	transcriptional antiterminator
GAN20_RS00645	COG0628	permease
GAN20_RS00665	COG1942	4-Oxalocrotonate Tautomerase
GAN20_RS00675	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GAN20_RS00680	COG0287	Prephenate dehydrogenase
GAN20_RS00685	COG1363	Peptidase, m42
GAN20_RS00715	COG2996	Protein conserved in bacteria
GAN20_RS00720	COG0488	(ABC) transporter
GAN20_RS00725	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
GAN20_RS00730	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GAN20_RS00735	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
GAN20_RS00740	COG2171	N-acyltransferase activity
GAN20_RS00745	COG1473	amidohydrolase
GAN20_RS00765	COG1278	Cold shock
GAN20_RS00785	COG3853	Toxic anion resistance protein (TelA)
GAN20_RS00795	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
GAN20_RS00800	COG1114	Component of the transport system for branched-chain amino acids
GAN20_RS00805	COG4548	von Willebrand factor, type A
GAN20_RS00810	COG0714	Associated with various cellular activities
GAN20_RS00835	COG0567	Dehydrogenase, E1 component
GAN20_RS00840	COG5002	protein histidine kinase activity
GAN20_RS00850	COG0671	phosphoesterase, PA-phosphatase related
GAN20_RS00855	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
GAN20_RS00865	COG0793	Belongs to the peptidase S41A family
GAN20_RS00875	COG2190	(PTS) system
GAN20_RS00910	COG1413	lyase activity
GAN20_RS00920	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
GAN20_RS00930	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GAN20_RS00935	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
GAN20_RS00940	COG2962	Rard protein
GAN20_RS00945	COG0116	Belongs to the methyltransferase superfamily
GAN20_RS00955	COG3599	regulation of cell shape
GAN20_RS00960	COG4474	Belongs to the UPF0398 family
GAN20_RS00975	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GAN20_RS00975	COG4499	WXG100 protein secretion system (Wss), protein YukC
GAN20_RS00985	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
GAN20_RS00990	COG3935	DnaD domain protein
GAN20_RS00995	COG0017	Asparaginyl-tRNA synthetase
GAN20_RS01010	COG0617	tRNA 3'-terminal CCA addition
GAN20_RS01015	COG0438	transferase activity, transferring glycosyl groups
GAN20_RS01020	COG1694	Mazg nucleotide pyrophosphohydrolase
GAN20_RS01030	COG4347	Protein of unknown function (DUF1405)
GAN20_RS01035	COG5582	Belongs to the UPF0302 family
GAN20_RS01040	COG0457	Tetratricopeptide repeat
GAN20_RS01050	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
GAN20_RS01060	COG0105	UTP biosynthetic process
GAN20_RS01065	COG0142	geranyltranstransferase activity
GAN20_RS01085	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
GAN20_RS01090	COG1160	GTP binding
GAN20_RS01095	COG0539	negative regulation of cytoplasmic translation
GAN20_RS01105	COG0252	asparaginase activity
GAN20_RS01110	COG0492	ferredoxin-NADP+ reductase activity
GAN20_RS01120	COG0514	ATP-dependent DNA helicase (RecQ)
GAN20_RS01130	COG1141	Ferredoxin
GAN20_RS01145	COG0745	RESPONSE REGULATOR receiver
GAN20_RS01150	COG1187	pseudouridine synthase activity
GAN20_RS01155	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
GAN20_RS01160	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
GAN20_RS01175	COG0735	belongs to the Fur family
GAN20_RS01180	COG0494	nUDIX hydrolase
GAN20_RS01185	COG0667	Aldo Keto reductase
GAN20_RS01195	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GAN20_RS01200	COG1234	tRNA 3'-trailer cleavage
GAN20_RS01205	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
GAN20_RS01235	COG2195	Cleaves the N-terminal amino acid of tripeptides
GAN20_RS01245	COG4129	membrane
GAN20_RS01255	COG0508	dehydrogenase complex catalyzes the overall conversion of
GAN20_RS01260	COG0022	dehydrogenase e1 component
GAN20_RS01265	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
GAN20_RS01270	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GAN20_RS01275	COG3426	butyrate kinase activity
GAN20_RS01280	COG0280	phosphate acetyltransferase
GAN20_RS01285	COG0497	DNA recombination
GAN20_RS01290	COG1438	arginine binding
GAN20_RS01295	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
GAN20_RS01300	COG0142	geranyltranstransferase activity
GAN20_RS01305	COG1722	exodeoxyribonuclease VII activity
GAN20_RS01310	COG1570	exodeoxyribonuclease VII activity
GAN20_RS01320	COG1302	Protein conserved in bacteria
GAN20_RS01325	COG0439	Biotin carboxylase
GAN20_RS01330	COG0511	ligase activity, forming carbon-carbon bonds
GAN20_RS01335	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
GAN20_RS01340	COG0006	proline dipeptidase activity
GAN20_RS01355	COG0095	Lipoate-protein ligase
GAN20_RS01360	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GAN20_RS01365	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GAN20_RS01375	COG0404	The glycine cleavage system catalyzes the degradation of glycine
GAN20_RS01380	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
GAN20_RS01410	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GAN20_RS01415	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GAN20_RS01420	COG0011	TIGRFAM Protein of
GAN20_RS01425	COG1940	carbohydrate kinase activity
GAN20_RS01430	COG4483	Protein conserved in bacteria
GAN20_RS01435	COG0705	Rhomboid family
GAN20_RS01440	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
GAN20_RS01450	COG0704	Plays a role in the regulation of phosphate uptake
GAN20_RS01455	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
GAN20_RS01460	COG0581	inorganic phosphate transmembrane transporter activity
GAN20_RS01465	COG0573	inorganic phosphate transmembrane transporter activity
GAN20_RS01470	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
GAN20_RS01475	COG0768	penicillin binding
GAN20_RS01485	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
GAN20_RS01490	COG0735	belongs to the Fur family
GAN20_RS01495	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GAN20_RS01500	COG1121	(ABC) transporter
GAN20_RS01505	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
GAN20_RS01510	COG0513	Belongs to the DEAD box helicase family
GAN20_RS01515	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
GAN20_RS01520	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
GAN20_RS01525	COG2384	SAM-dependent methyltransferase
GAN20_RS01530	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GAN20_RS01535	COG0358	DNA primase activity
GAN20_RS01540	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
GAN20_RS01545	COG0517	IMP dehydrogenase activity
GAN20_RS01550	COG0423	glycine-tRNA ligase activity
GAN20_RS01555	COG1381	Involved in DNA repair and RecF pathway recombination
GAN20_RS01560	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
GAN20_RS01570	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
GAN20_RS01580	COG1702	phosphate starvation-inducible protein PhoH
GAN20_RS01590	COG4864	UPF0365 protein
GAN20_RS01595	COG1030	water channel activity
GAN20_RS01610	COG3344	reverse transcriptase
GAN20_RS01615	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GAN20_RS01620	COG1385	rRNA (uridine-N3-)-methyltransferase activity
GAN20_RS01625	COG2264	protein methyltransferase activity
GAN20_RS01630	COG0484	heat shock protein binding
GAN20_RS01650	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GAN20_RS01660	COG0268	Binds directly to 16S ribosomal RNA
GAN20_RS01665	COG1466	dna polymerase III delta subunit
GAN20_RS01670	COG2333	competence protein COMEC
GAN20_RS01670	COG0658	competence protein
GAN20_RS01675	COG2131	deaminase
GAN20_RS01680	COG1596	polysaccharide export
GAN20_RS01680	COG1555	photosystem II stabilization
GAN20_RS01685	COG2226	methyltransferase
GAN20_RS01690	COG0799	negative regulation of ribosome biogenesis
GAN20_RS01695	COG1713	HD superfamily hydrolase involved in NAD metabolism
GAN20_RS01705	COG1534	Rna-binding protein
GAN20_RS01710	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
GAN20_RS01715	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
GAN20_RS01720	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
GAN20_RS01725	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
GAN20_RS01730	COG1914	H( )-stimulated, divalent metal cation uptake system
GAN20_RS01735	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
GAN20_RS01740	COG0439	Biotin carboxylase
GAN20_RS01745	COG0511	ligase activity, forming carbon-carbon bonds
GAN20_RS01750	COG1984	allophanate hydrolase subunit 2
GAN20_RS01755	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
GAN20_RS01765	COG0572	uridine kinase
GAN20_RS01770	COG0826	peptidase U32
GAN20_RS01775	COG0826	peptidase U32
GAN20_RS01780	COG4122	O-methyltransferase activity
GAN20_RS01785	COG3906	Belongs to the UPF0473 family
GAN20_RS01790	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
GAN20_RS01795	COG4472	Bacterial protein of unknown function (DUF965)
GAN20_RS01800	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
GAN20_RS01805	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
GAN20_RS01815	COG0482	sulfurtransferase activity
GAN20_RS01820	COG1104	cysteine desulfurase activity
GAN20_RS01825	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GAN20_RS01840	COG1959	2 iron, 2 sulfur cluster binding
GAN20_RS01845	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
GAN20_RS01850	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
GAN20_RS01860	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
GAN20_RS01870	COG0860	N-Acetylmuramoyl-L-alanine amidase
GAN20_RS01875	COG1490	D-aminoacyl-tRNA deacylase activity
GAN20_RS01885	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GAN20_RS01890	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
GAN20_RS01890	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
GAN20_RS01895	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GAN20_RS01895	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GAN20_RS01900	COG1862	Preprotein translocase
GAN20_RS01910	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
GAN20_RS01915	COG2255	four-way junction helicase activity
GAN20_RS01920	COG0632	four-way junction helicase activity
GAN20_RS01930	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
GAN20_RS01940	COG2868	ribosomal protein
GAN20_RS01965	COG2003	Belongs to the UPF0758 family
GAN20_RS01975	COG0285	dihydrofolate synthase activity
GAN20_RS01980	COG0525	valine-tRNA ligase activity
GAN20_RS01985	COG2818	Glycosylase
GAN20_RS01995	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
GAN20_RS02010	COG0181	hydroxymethylbilane synthase activity
GAN20_RS02020	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
GAN20_RS02025	COG0218	Necessary for normal cell division and for the maintenance of normal septation
GAN20_RS02035	COG0544	peptidyl-prolyl cis-trans isomerase activity
GAN20_RS02050	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
GAN20_RS02055	COG0291	Belongs to the bacterial ribosomal protein bL35 family
GAN20_RS02060	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
GAN20_RS02065	COG0833	amino acid
GAN20_RS02075	COG1484	DNA-dependent DNA replication
GAN20_RS02080	COG3611	Membrane attachment protein
GAN20_RS02095	COG0237	dephospho-CoA kinase activity
GAN20_RS02105	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GAN20_RS02105	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GAN20_RS02110	COG5002	protein histidine kinase activity
GAN20_RS02115	COG0745	RESPONSE REGULATOR receiver
GAN20_RS02120	COG0538	isocitrate dehydrogenase activity
GAN20_RS02125	COG0372	Belongs to the citrate synthase family
GAN20_RS02130	COG0469	pyruvate kinase activity
GAN20_RS02135	COG0205	6-phosphofructokinase activity
GAN20_RS02140	COG0825	malonyl-CoA metabolic process
GAN20_RS02145	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
GAN20_RS02150	COG0281	malic enzyme
GAN20_RS02155	COG0587	DNA-directed DNA polymerase activity
GAN20_RS02160	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
GAN20_RS02165	COG4109	DRTGG domain
GAN20_RS02175	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
GAN20_RS02180	COG0006	proline dipeptidase activity
GAN20_RS02190	COG0686	Belongs to the AlaDH PNT family
GAN20_RS02195	COG0589	response to stress
GAN20_RS02200	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
GAN20_RS02205	COG0827	DNA restriction-modification system
GAN20_RS02210	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
GAN20_RS02215	COG1714	RDD family
GAN20_RS02220	COG0616	signal peptide processing
GAN20_RS02230	COG0301	tRNA thio-modification
GAN20_RS02235	COG1104	cysteine desulfurase activity
GAN20_RS02240	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
GAN20_RS02245	COG1956	GAF domain-containing protein
GAN20_RS02250	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
GAN20_RS02285	COG0456	acetyltransferase
GAN20_RS02325	COG1764	response to oxidative stress
GAN20_RS02330	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
GAN20_RS02335	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GAN20_RS02345	COG0204	Acyl-transferase
GAN20_RS02350	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GAN20_RS02360	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
GAN20_RS02365	COG2759	Belongs to the formate--tetrahydrofolate ligase family
GAN20_RS02370	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GAN20_RS02375	COG0454	-acetyltransferase
GAN20_RS02385	COG1609	Transcriptional regulator
GAN20_RS02390	COG1605	Chorismate mutase
GAN20_RS02390	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
GAN20_RS02400	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
GAN20_RS02405	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
GAN20_RS02410	COG1674	ftsk spoiiie
GAN20_RS02415	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GAN20_RS02420	COG4848	Belongs to the UPF0354 family
GAN20_RS02425	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GAN20_RS02430	COG1363	Peptidase, m42
GAN20_RS02440	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GAN20_RS02445	COG0220	tRNA (guanine-N7-)-methyltransferase activity
GAN20_RS02450	COG0510	thiamine kinase activity
GAN20_RS02455	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GAN20_RS02460	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GAN20_RS02470	COG1187	pseudouridine synthase activity
GAN20_RS02475	COG2244	polysaccharide biosynthetic process
GAN20_RS02480	COG2081	HI0933 family
GAN20_RS02485	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GAN20_RS02490	COG0495	leucyl-tRNA aminoacylation
GAN20_RS02495	COG2814	Major facilitator Superfamily
GAN20_RS02500	COG1242	4 iron, 4 sulfur cluster binding
GAN20_RS02505	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
GAN20_RS02515	COG0039	L-malate dehydrogenase activity
GAN20_RS02520	COG2267	carboxylic ester hydrolase activity
GAN20_RS02535	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
GAN20_RS02540	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GAN20_RS02540	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GAN20_RS02545	COG0307	riboflavin synthase, alpha
GAN20_RS02550	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GAN20_RS02550	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GAN20_RS02560	COG4193	domain, Protein
GAN20_RS02560	COG3266	domain, Protein
GAN20_RS02560	COG5632	N-Acetylmuramoyl-L-alanine amidase
GAN20_RS02585	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
GAN20_RS02595	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GAN20_RS02600	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GAN20_RS02605	COG0656	L-ascorbic acid biosynthetic process
GAN20_RS02615	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
GAN20_RS02620	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
GAN20_RS02625	COG1506	peptidase
GAN20_RS02630	COG0494	nUDIX hydrolase
GAN20_RS02635	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
GAN20_RS02655	COG0235	Class ii aldolase
GAN20_RS02660	COG3623	hexulose-6-phosphate isomerase
GAN20_RS02680	COG3037	sugar-specific permease SgaT UlaA
GAN20_RS02770	COG3545	Serine hydrolase
GAN20_RS02775	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
GAN20_RS02785	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
GAN20_RS02795	COG3344	reverse transcriptase
GAN20_RS02800	COG4473	ABC transporter
GAN20_RS02805	COG1131	(ABC) transporter
GAN20_RS02810	COG0537	adenosine 5'-monophosphoramidase activity
GAN20_RS02820	COG1846	Transcriptional regulator
GAN20_RS02835	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GAN20_RS02840	COG3481	metal-dependent phosphohydrolase, HD sub domain
GAN20_RS02850	COG0420	3'-5' exonuclease activity
GAN20_RS02855	COG3679	Belongs to the UPF0342 family
GAN20_RS02860	COG4399	Belongs to the UPF0754 family
GAN20_RS02875	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
GAN20_RS02885	COG2197	response regulator
GAN20_RS02890	COG2203	Gaf domain
GAN20_RS02890	COG4585	Histidine kinase
GAN20_RS02895	COG0564	pseudouridine synthase activity
GAN20_RS02900	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
GAN20_RS02905	COG0248	Ppx GppA phosphatase
GAN20_RS02910	COG0114	fumarate hydratase activity
GAN20_RS02920	COG0363	glucosamine-6-phosphate deaminase activity
GAN20_RS02930	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
GAN20_RS02935	COG1126	abc transporter atp-binding protein
GAN20_RS02940	COG0765	amino acid transport
GAN20_RS03105	COG0735	belongs to the Fur family
GAN20_RS03115	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
GAN20_RS03120	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
GAN20_RS03125	COG4129	membrane
GAN20_RS03130	COG0069	glutamate synthase activity
GAN20_RS03140	COG3557	Belongs to the UPF0374 family
GAN20_RS03145	COG1194	a g-specific adenine glycosylase
GAN20_RS03150	COG1988	membrane-bound metal-dependent
GAN20_RS03160	COG1388	LysM domain
GAN20_RS03160	COG1134	teichoic acid transport
GAN20_RS03170	COG2137	regulation of response to DNA damage stimulus
GAN20_RS03175	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GAN20_RS03180	COG0028	Belongs to the TPP enzyme family
GAN20_RS03185	COG0693	protein deglycase activity
GAN20_RS03190	COG0535	radical SAM domain protein
GAN20_RS03195	COG1607	acyl-coa hydrolase
GAN20_RS03200	COG2309	aminopeptidase activity
GAN20_RS03205	COG4840	Belongs to the UPF0435 family
GAN20_RS03220	COG1295	ribonuclease BN
GAN20_RS03225	COG0288	reversible hydration of carbon dioxide
GAN20_RS03250	COG0024	Methionine aminopeptidase
GAN20_RS03255	COG4129	membrane
GAN20_RS03270	COG1528	Iron-storage protein
GAN20_RS03280	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GAN20_RS03290	COG2211	Major facilitator Superfamily
GAN20_RS03300	COG1396	sequence-specific DNA binding
GAN20_RS03310	COG0488	(ABC) transporter
GAN20_RS03335	COG1597	lipid kinase activity
GAN20_RS03340	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GAN20_RS03350	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GAN20_RS03355	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GAN20_RS03360	COG4851	CamS sex pheromone cAM373 precursor
GAN20_RS03365	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
GAN20_RS03370	COG0210	DNA helicase
GAN20_RS03375	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
GAN20_RS03380	COG4496	protein, YerC YecD
GAN20_RS03385	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
GAN20_RS03395	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
GAN20_RS03405	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
GAN20_RS03415	COG0077	Prephenate dehydratase
GAN20_RS03415	COG1605	Chorismate mutase
GAN20_RS03425	COG1335	isochorismatase
GAN20_RS03430	COG1227	inorganic diphosphatase activity
GAN20_RS03440	COG1012	belongs to the aldehyde dehydrogenase family
GAN20_RS03445	COG2706	6-phosphogluconolactonase activity
GAN20_RS03475	COG2610	gluconate transmembrane transporter activity
GAN20_RS03480	COG1070	Carbohydrate kinase
GAN20_RS03495	COG1131	(ABC) transporter
GAN20_RS03510	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GAN20_RS03515	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GAN20_RS03555	COG4512	PFAM Accessory gene regulator B
GAN20_RS03575	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GAN20_RS03580	COG1621	beta-fructofuranosidase activity
GAN20_RS03585	COG1609	Transcriptional regulator
GAN20_RS03595	COG2124	cytochrome p450
GAN20_RS03605	COG1846	Transcriptional regulator
GAN20_RS03610	COG2814	Major facilitator Superfamily
GAN20_RS03615	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
GAN20_RS03620	COG0488	(ABC) transporter
GAN20_RS03625	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
GAN20_RS03635	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
GAN20_RS03640	COG0456	acetyltransferase
GAN20_RS03645	COG1214	PFAM Peptidase M22, glycoprotease
GAN20_RS03650	COG0802	atpase or kinase
GAN20_RS03655	COG0129	dihydroxy-acid dehydratase activity
GAN20_RS03660	COG0028	Belongs to the TPP enzyme family
GAN20_RS03670	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
GAN20_RS03675	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GAN20_RS03685	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
GAN20_RS03730	COG3091	SprT-like family
GAN20_RS03735	COG2183	response to ionizing radiation
GAN20_RS03740	COG1191	sigma factor activity
GAN20_RS03750	COG1366	Belongs to the anti-sigma-factor antagonist family
GAN20_RS03755	COG2208	phosphoserine phosphatase activity
GAN20_RS03760	COG2337	Toxic component of a toxin-antitoxin (TA) module
GAN20_RS03770	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GAN20_RS03775	COG0736	holo-[acyl-carrier-protein] synthase activity
GAN20_RS03780	COG3402	PFAM membrane-flanked domain
GAN20_RS03795	COG0513	Belongs to the DEAD box helicase family
GAN20_RS03800	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
GAN20_RS03805	COG1181	Belongs to the D-alanine--D-alanine ligase family
GAN20_RS03810	COG0772	Belongs to the SEDS family
GAN20_RS03820	COG2217	Heavy metal translocating P-type atpase
GAN20_RS03835	COG1937	Protein conserved in bacteria
GAN20_RS03840	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GAN20_RS03845	COG1418	mRNA catabolic process
GAN20_RS03850	COG0706	membrane insertase activity
GAN20_RS03855	COG0352	thiamine-phosphate diphosphorylase activity
GAN20_RS03860	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
GAN20_RS03870	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
GAN20_RS03885	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
GAN20_RS03915	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
GAN20_RS03925	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GAN20_RS03935	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GAN20_RS03940	COG0356	it plays a direct role in the translocation of protons across the membrane
GAN20_RS03950	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
GAN20_RS03955	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
GAN20_RS03960	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
GAN20_RS03965	COG4475	Protein of unknown function (DUF436)
GAN20_RS03970	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GAN20_RS03975	COG0009	L-threonylcarbamoyladenylate synthase
GAN20_RS03980	COG2890	protein-(glutamine-N5) methyltransferase activity
GAN20_RS03985	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
GAN20_RS03995	COG0254	rRNA binding
GAN20_RS04000	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
GAN20_RS04015	COG1733	regulation of RNA biosynthetic process
GAN20_RS04020	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GAN20_RS04025	COG0191	fructose-bisphosphate aldolase activity
GAN20_RS04030	COG4821	SIS domain
GAN20_RS04035	COG2271	Major facilitator Superfamily
GAN20_RS04040	COG0504	CTP synthase activity
GAN20_RS04050	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GAN20_RS04065	COG5146	pantothenate kinase activity
GAN20_RS04100	COG0813	purine-nucleoside phosphorylase activity
GAN20_RS04110	COG1757	Na H antiporter
GAN20_RS04125	COG1482	cell wall glycoprotein biosynthetic process
GAN20_RS04130	COG2186	Transcriptional regulator
GAN20_RS04140	COG0561	phosphatase activity
GAN20_RS04145	COG1119	ATPase activity
GAN20_RS04160	COG3421	Type III restriction
GAN20_RS04165	COG2189	Belongs to the N(4) N(6)-methyltransferase family
GAN20_RS04185	COG0210	DNA helicase
GAN20_RS04190	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
GAN20_RS04235	COG3711	transcriptional antiterminator
GAN20_RS04250	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GAN20_RS04315	COG0489	protein tyrosine kinase activity
GAN20_RS04320	COG2814	Major facilitator Superfamily
GAN20_RS04340	COG1272	protein, Hemolysin III
GAN20_RS04345	COG4284	Utp--glucose-1-phosphate uridylyltransferase
GAN20_RS04350	COG1988	membrane-bound metal-dependent
GAN20_RS04360	COG3314	Sporulation integral membrane protein YlbJ
GAN20_RS04365	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GAN20_RS04370	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GAN20_RS04375	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
GAN20_RS04380	COG3457	Alanine racemase
GAN20_RS04385	COG4264	IucA IucC family
GAN20_RS04390	COG2814	Major facilitator Superfamily
GAN20_RS04395	COG4264	IucA IucC family
GAN20_RS04400	COG2814	Major facilitator Superfamily
GAN20_RS04405	COG1302	Protein conserved in bacteria
GAN20_RS04420	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
GAN20_RS04430	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GAN20_RS04435	COG0488	(ABC) transporter
GAN20_RS04445	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GAN20_RS04445	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GAN20_RS04455	COG3684	Belongs to the aldolase LacD family
GAN20_RS04470	COG1349	DNA-binding transcription factor activity
GAN20_RS04510	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GAN20_RS04535	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
GAN20_RS04540	COG0101	tRNA pseudouridine synthase activity
GAN20_RS04550	COG1122	ATPase activity
GAN20_RS04555	COG1122	ATPase activity
GAN20_RS04560	COG0203	ribosomal protein L17
GAN20_RS04565	COG0202	RNA polymerase activity
GAN20_RS04570	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
GAN20_RS04580	COG0257	Belongs to the bacterial ribosomal protein bL36 family
GAN20_RS04595	COG0201	protein transport
GAN20_RS04605	COG1841	ribosomal large subunit assembly
GAN20_RS04610	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
GAN20_RS04620	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
GAN20_RS04625	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
GAN20_RS04630	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
GAN20_RS04645	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
GAN20_RS04655	COG0255	Belongs to the universal ribosomal protein uL29 family
GAN20_RS04660	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
GAN20_RS04665	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
GAN20_RS04670	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
GAN20_RS04675	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
GAN20_RS04680	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
GAN20_RS04685	COG0089	rRNA binding
GAN20_RS04690	COG0088	Forms part of the polypeptide exit tunnel
GAN20_RS04695	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
GAN20_RS04715	COG2252	PERMEase
GAN20_RS04740	COG0436	Aminotransferase
GAN20_RS04745	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GAN20_RS04750	COG2348	transferase activity, transferring amino-acyl groups
GAN20_RS04775	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
GAN20_RS04780	COG0746	molybdenum cofactor guanylyltransferase activity
GAN20_RS04790	COG0314	molybdopterin synthase activity
GAN20_RS04810	COG0521	Mo-molybdopterin cofactor biosynthetic process
GAN20_RS04815	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
GAN20_RS04820	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
GAN20_RS04825	COG4149	molybdate abc transporter
GAN20_RS04835	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
GAN20_RS04840	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
GAN20_RS04845	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
GAN20_RS04850	COG1609	Transcriptional regulator
GAN20_RS04865	COG1268	BioY protein
GAN20_RS04875	COG2186	Transcriptional regulator
GAN20_RS04885	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GAN20_RS04890	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GAN20_RS04895	COG2832	Protein of unknown function (DUF454)
GAN20_RS04900	COG1388	LysM domain
GAN20_RS04900	COG5632	N-Acetylmuramoyl-L-alanine amidase
GAN20_RS05015	COG1783	phage Terminase large subunit
GAN20_RS05020	COG3728	DNA packaging
GAN20_RS05020	COG5484	DNA packaging
GAN20_RS05040	COG0756	dUTP diphosphatase activity
GAN20_RS05095	COG1484	DNA-dependent DNA replication
GAN20_RS05155	COG3422	double-strand break repair
GAN20_RS05165	COG3646	Phage regulatory protein
GAN20_RS05165	COG3645	SOS response
GAN20_RS05200	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
GAN20_RS05230	COG1960	acyl-CoA dehydrogenase activity
GAN20_RS05250	COG3942	CHAP domain
GAN20_RS05260	COG1757	Na H antiporter
GAN20_RS05270	COG3942	CHAP domain
GAN20_RS05275	COG2076	Multidrug Resistance protein
GAN20_RS05280	COG2076	Multidrug Resistance protein
GAN20_RS05285	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GAN20_RS05310	COG3383	formate dehydrogenase (NAD+) activity
GAN20_RS05315	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
GAN20_RS05330	COG1316	TRANSCRIPTIONal
GAN20_RS05355	COG1113	amino acid transport
GAN20_RS05380	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GAN20_RS05385	COG0346	lactoylglutathione lyase activity
GAN20_RS05395	COG0385	Bile acid
GAN20_RS05415	COG1473	amidohydrolase
GAN20_RS05420	COG0659	secondary active sulfate transmembrane transporter activity
GAN20_RS05425	COG1228	amidohydrolase
GAN20_RS05430	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
GAN20_RS05435	COG3314	Sporulation integral membrane protein YlbJ
GAN20_RS05440	COG0583	DNA-binding transcription factor activity
GAN20_RS05445	COG1266	CAAX protease self-immunity
GAN20_RS05455	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
GAN20_RS05460	COG2258	MOSC domain
GAN20_RS05465	COG2017	converts alpha-aldose to the beta-anomer
GAN20_RS05470	COG1742	UPF0060 membrane protein
GAN20_RS05475	COG1668	transmembrane transport
GAN20_RS05480	COG4152	abc transporter atp-binding protein
GAN20_RS05485	COG3152	Membrane
GAN20_RS05490	COG2094	Belongs to the DNA glycosylase MPG family
GAN20_RS05495	COG1757	Na H antiporter
GAN20_RS05515	COG3250	beta-galactosidase activity
GAN20_RS05520	COG2207	Transcriptional regulator
GAN20_RS05525	COG0786	glutamate:sodium symporter activity
GAN20_RS05550	COG0523	cobalamin synthesis protein
GAN20_RS05555	COG1304	FMN binding
GAN20_RS05575	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GAN20_RS05585	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
GAN20_RS05595	COG3344	reverse transcriptase
GAN20_RS05625	COG0577	efflux transmembrane transporter activity
GAN20_RS05640	COG0579	oxidoreductase
GAN20_RS05645	COG0438	transferase activity, transferring glycosyl groups
GAN20_RS05650	COG1620	l-lactate permease
GAN20_RS05680	COG0604	alcohol dehydrogenase
GAN20_RS05685	COG2814	Major facilitator Superfamily
GAN20_RS05690	COG0492	ferredoxin-NADP+ reductase activity
GAN20_RS05710	COG1283	sodium-dependent phosphate transmembrane transporter activity
GAN20_RS05725	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GAN20_RS05725	COG1263	PTS System
GAN20_RS05735	COG2807	transmembrane transport
GAN20_RS05745	COG0697	spore germination
GAN20_RS05750	COG1363	Peptidase, m42
GAN20_RS05755	COG0039	L-malate dehydrogenase activity
GAN20_RS05765	COG4187	Peptidase family M20/M25/M40
GAN20_RS05770	COG3344	reverse transcriptase
GAN20_RS05775	COG2223	nitrite transmembrane transporter activity
GAN20_RS05785	COG2197	response regulator
GAN20_RS05790	COG4585	Histidine kinase
GAN20_RS05800	COG2181	nitrate reductase activity
GAN20_RS05810	COG1140	nitrate reductase beta subunit
GAN20_RS05815	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
GAN20_RS05825	COG0737	Belongs to the 5'-nucleotidase family
GAN20_RS05830	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
GAN20_RS05830	COG1648	precorrin-2 dehydrogenase activity
GAN20_RS05835	COG2146	nitrite reductase [NAD(P)H] activity
GAN20_RS05840	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GAN20_RS05845	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
GAN20_RS05845	COG1648	precorrin-2 dehydrogenase activity
GAN20_RS05855	COG0454	-acetyltransferase
GAN20_RS05860	COG2116	formate transmembrane transporter activity
GAN20_RS05865	COG0471	metal ion transport
GAN20_RS05915	COG1760	l-serine dehydratase
GAN20_RS05920	COG1760	l-serine dehydratase
GAN20_RS05935	COG0702	epimerase
GAN20_RS05940	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
GAN20_RS05960	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
GAN20_RS05970	COG1929	Belongs to the glycerate kinase type-1 family
GAN20_RS05975	COG3764	Sortase (surface protein transpeptidase)
GAN20_RS05980	COG2271	Major facilitator Superfamily
GAN20_RS05985	COG2814	Major facilitator Superfamily
GAN20_RS05990	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
GAN20_RS05995	COG1115	amino acid carrier protein
GAN20_RS06005	COG0346	lactoylglutathione lyase activity
GAN20_RS06030	COG1674	ftsk spoiiie
GAN20_RS06040	COG2946	Replication initiation factor
GAN20_RS06070	COG0741	lytic transglycosylase activity
GAN20_RS06070	COG0791	NLP P60 protein
GAN20_RS06140	COG1132	(ABC) transporter
GAN20_RS06145	COG1132	(ABC) transporter
GAN20_RS06150	COG0247	lactate metabolic process
GAN20_RS06155	COG0277	FAD linked oxidase domain protein
GAN20_RS06175	COG0159	tryptophan synthase activity
GAN20_RS06180	COG0133	tryptophan synthase activity
GAN20_RS06190	COG0134	indole-3-glycerol-phosphate synthase activity
GAN20_RS06200	COG0512	Glutamine amidotransferase of anthranilate synthase
GAN20_RS06205	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
GAN20_RS06210	COG3961	Belongs to the TPP enzyme family
GAN20_RS06215	COG2855	membrane
GAN20_RS06220	COG3835	regulator
GAN20_RS06235	COG1028	Short-chain dehydrogenase reductase Sdr
GAN20_RS06275	COG2357	RelA SpoT domain protein
GAN20_RS06280	COG0778	Nitroreductase
GAN20_RS06285	COG1846	Transcriptional regulator
GAN20_RS06300	COG1346	cytolysis
GAN20_RS06310	COG0583	DNA-binding transcription factor activity
GAN20_RS06340	COG1141	Ferredoxin
GAN20_RS06350	COG0523	cobalamin synthesis protein
GAN20_RS06355	COG0717	Belongs to the dCTP deaminase family
GAN20_RS06360	COG0804	urea catabolic process
GAN20_RS06365	COG0832	Belongs to the urease beta subunit family
GAN20_RS06375	COG4413	Urea transporter
GAN20_RS06395	COG0577	efflux transmembrane transporter activity
GAN20_RS06400	COG1136	(ABC) transporter
GAN20_RS06425	COG3001	Fructosamine kinase
GAN20_RS06430	COG0778	Nitroreductase
GAN20_RS06435	COG3181	Tripartite tricarboxylate transporter family receptor
GAN20_RS06450	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
GAN20_RS06455	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GAN20_RS06460	COG0463	Glycosyl transferase, family 2
GAN20_RS06460	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
GAN20_RS06485	COG0747	negative chemotaxis
GAN20_RS06490	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
GAN20_RS06495	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
GAN20_RS06510	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
GAN20_RS06520	COG1705	Flagellar rod assembly protein muramidase FlgJ
GAN20_RS06520	COG3942	CHAP domain
GAN20_RS06530	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GAN20_RS06530	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GAN20_RS06530	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GAN20_RS06535	COG0789	Transcriptional regulator
GAN20_RS06540	COG0596	Alpha beta hydrolase
GAN20_RS06555	COG1012	belongs to the aldehyde dehydrogenase family
GAN20_RS06560	COG2824	Alkylphosphonate utilization operon protein PhnA
GAN20_RS06565	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
GAN20_RS06570	COG1461	Dihydroxyacetone kinase
GAN20_RS06575	COG2376	Dihydroxyacetone kinase
GAN20_RS06610	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
GAN20_RS06615	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
GAN20_RS06620	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
GAN20_RS06625	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
GAN20_RS06640	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
GAN20_RS06645	COG0107	imidazoleglycerol-phosphate synthase activity
GAN20_RS06660	COG0156	8-amino-7-oxononanoate synthase activity
GAN20_RS06670	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
GAN20_RS06675	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
GAN20_RS06680	COG1012	belongs to the aldehyde dehydrogenase family
GAN20_RS06685	COG1510	regulation of RNA biosynthetic process
GAN20_RS06705	COG0494	nUDIX hydrolase
GAN20_RS06710	COG1785	Belongs to the alkaline phosphatase family
GAN20_RS06725	COG1396	sequence-specific DNA binding
GAN20_RS06730	COG2807	transmembrane transport
GAN20_RS06735	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
GAN20_RS06740	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
GAN20_RS06755	COG1957	nucleoside hydrolase
GAN20_RS06760	COG3250	beta-galactosidase activity
GAN20_RS06765	COG2211	Major facilitator Superfamily
GAN20_RS06770	COG0477	Major facilitator Superfamily
GAN20_RS06775	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
GAN20_RS06780	COG1210	Utp--glucose-1-phosphate uridylyltransferase
GAN20_RS06790	COG2972	Histidine kinase
GAN20_RS06795	COG4753	response regulator
GAN20_RS06795	COG2207	Transcriptional regulator
GAN20_RS06820	COG3443	Belongs to the bacterial solute-binding protein 9 family
GAN20_RS06820	COG0803	Belongs to the bacterial solute-binding protein 9 family
GAN20_RS06830	COG1942	4-Oxalocrotonate Tautomerase
GAN20_RS06835	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GAN20_RS06855	COG1328	CTP reductase activity
GAN20_RS06865	COG3037	sugar-specific permease SgaT UlaA
GAN20_RS06875	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GAN20_RS06880	COG3711	transcriptional antiterminator
GAN20_RS06910	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GAN20_RS06915	COG1609	Transcriptional regulator
GAN20_RS06935	COG1116	anion transmembrane transporter activity
GAN20_RS06945	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GAN20_RS06955	COG2814	Major facilitator Superfamily
GAN20_RS06965	COG0318	PFAM AMP-dependent synthetase and ligase
GAN20_RS06980	COG0183	Belongs to the thiolase family
GAN20_RS06985	COG0438	transferase activity, transferring glycosyl groups
GAN20_RS07005	COG1073	alpha beta
GAN20_RS07025	COG0579	oxidoreductase
GAN20_RS07050	COG1755	Isoprenylcysteine carboxyl methyltransferase
GAN20_RS07060	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GAN20_RS07070	COG1136	(ABC) transporter
GAN20_RS07095	COG0436	Aminotransferase
GAN20_RS07105	COG0783	Belongs to the Dps family
GAN20_RS07115	COG0753	catalase activity
GAN20_RS07120	COG2318	DinB family
GAN20_RS07135	COG0076	glutamate decarboxylase activity
GAN20_RS07150	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
GAN20_RS07195	COG0156	8-amino-7-oxononanoate synthase activity
GAN20_RS07200	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
GAN20_RS07205	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
GAN20_RS07210	COG1620	l-lactate permease
GAN20_RS07225	COG1063	alcohol dehydrogenase
GAN20_RS07245	COG3314	Sporulation integral membrane protein YlbJ
GAN20_RS07265	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
GAN20_RS07275	COG3716	PTS system mannose fructose sorbose family IID component
GAN20_RS07280	COG3715	PTS system
GAN20_RS07285	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GAN20_RS07285	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
GAN20_RS07300	COG1105	Belongs to the carbohydrate kinase PfkB family
GAN20_RS07305	COG2222	sugar isomerase
GAN20_RS07310	COG2188	Transcriptional regulator
GAN20_RS07315	COG0366	Alpha amylase catalytic
GAN20_RS07325	COG1131	(ABC) transporter
GAN20_RS07360	COG0346	lactoylglutathione lyase activity
GAN20_RS07370	COG0490	domain, Protein
GAN20_RS07375	COG0475	glutathione-regulated potassium exporter activity
GAN20_RS07380	COG3842	ATPase activity
GAN20_RS07390	COG1175	transmembrane transport
GAN20_RS07395	COG3833	ABC-type maltose transport systems, permease component
GAN20_RS07405	COG0366	Alpha amylase catalytic
GAN20_RS07415	COG0673	inositol 2-dehydrogenase activity
GAN20_RS07425	COG1609	Transcriptional regulator
GAN20_RS07445	COG3583	domain protein
GAN20_RS07445	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
GAN20_RS07445	COG4932	domain protein
GAN20_RS07450	COG0431	NADPH-dependent FMN reductase
GAN20_RS07470	COG1131	(ABC) transporter
GAN20_RS07475	COG0842	Transport permease protein
GAN20_RS07480	COG2203	Gaf domain
GAN20_RS07480	COG4585	Histidine kinase
GAN20_RS07485	COG2197	response regulator
GAN20_RS07500	COG2235	arginine
GAN20_RS07520	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GAN20_RS07525	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
GAN20_RS07535	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GAN20_RS07540	COG3177	Filamentation induced by cAMP protein fic
GAN20_RS07555	COG2130	NADP-dependent
GAN20_RS07560	COG0702	epimerase
GAN20_RS07575	COG0415	Belongs to the DNA photolyase family
GAN20_RS07585	COG2723	6-phospho-beta-galactosidase activity
GAN20_RS07590	COG2188	Transcriptional regulator
GAN20_RS07605	COG3655	Transcriptional regulator
GAN20_RS07620	COG2217	Heavy metal translocating P-type atpase
GAN20_RS07625	COG0531	amino acid
GAN20_RS07645	COG2311	Membrane
GAN20_RS07660	COG2132	Multicopper oxidase
GAN20_RS07670	COG0745	RESPONSE REGULATOR receiver
GAN20_RS07675	COG5002	protein histidine kinase activity
GAN20_RS07680	COG1388	LysM domain
GAN20_RS07685	COG3682	Transcriptional regulator
GAN20_RS07700	COG0785	Cytochrome C biogenesis protein
GAN20_RS07730	COG0730	response to heat
GAN20_RS07735	COG1937	Protein conserved in bacteria
GAN20_RS07740	COG2210	Belongs to the sulfur carrier protein TusA family
GAN20_RS07745	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GAN20_RS07755	COG1940	carbohydrate kinase activity
GAN20_RS07755	COG1846	Transcriptional regulator
GAN20_RS07780	COG2030	dehydratase
GAN20_RS07785	COG0584	glycerophosphoryl diester phosphodiesterase
GAN20_RS07795	COG3425	synthase
GAN20_RS07805	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
GAN20_RS07810	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
GAN20_RS07820	COG4863	YycH protein
GAN20_RS07825	COG5002	protein histidine kinase activity
GAN20_RS07830	COG0745	RESPONSE REGULATOR receiver
GAN20_RS07850	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GAN20_RS07855	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
GAN20_RS07860	COG0305	Participates in initiation and elongation during chromosome replication
GAN20_RS07870	COG0359	binds to the 23S rRNA
GAN20_RS07875	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
GAN20_RS07880	COG4241	membrane
GAN20_RS07885	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
GAN20_RS07895	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
GAN20_RS07905	COG2986	histidine ammonia-lyase
GAN20_RS07910	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
GAN20_RS07920	COG0187	DNA topoisomerase II activity
GAN20_RS07925	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
GAN20_RS07930	COG2501	S4 domain
GAN20_RS07935	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
GAN20_RS07935	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
GAN20_RS07940	COG0592	DNA-directed DNA polymerase activity
GAN20_RS07945	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
GAN20_RS07955	COG0594	ribonuclease P activity
GAN20_RS07960	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
GAN20_RS07965	COG0445	tRNA wobble uridine modification
GAN20_RS07970	COG0357	Ribosomal RNA small subunit methyltransferase G
GAN20_RS07995	COG0400	carboxylic ester hydrolase activity
GAN20_RS08000	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GAN20_RS08005	COG0346	lactoylglutathione lyase activity
GAN20_RS08010	COG1846	Transcriptional regulator
GAN20_RS08015	COG2388	GCN5-related N-acetyl-transferase
GAN20_RS08025	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
GAN20_RS08030	COG0830	nickel cation binding
GAN20_RS08040	COG0829	nickel cation binding
GAN20_RS08050	COG0646	methionine synthase
GAN20_RS08050	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
GAN20_RS08055	COG0626	cystathionine gamma-synthase activity
GAN20_RS08060	COG0626	cystathionine gamma-synthase activity
GAN20_RS08065	COG1475	DNA binding
GAN20_RS08070	COG0668	transmembrane transport
GAN20_RS08075	COG4481	Protein conserved in bacteria
GAN20_RS08080	COG0012	GTP binding
GAN20_RS08085	COG1131	(ABC) transporter
GAN20_RS08090	COG1668	transmembrane transport
GAN20_RS08100	COG0360	Binds together with S18 to 16S ribosomal RNA
GAN20_RS08110	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
GAN20_RS08115	COG2207	Transcriptional regulator
GAN20_RS08115	COG0662	Cupin 2, conserved barrel domain protein
GAN20_RS08125	COG1175	transmembrane transport
GAN20_RS08130	COG0395	ABC-type sugar transport system, permease component
GAN20_RS08135	COG0673	inositol 2-dehydrogenase activity
GAN20_RS08140	COG3842	ATPase activity
GAN20_RS08145	COG0753	catalase activity
GAN20_RS08150	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
GAN20_RS08155	COG1464	Belongs to the NlpA lipoprotein family
GAN20_RS08160	COG2011	ABC-type metal ion transport system permease component
GAN20_RS08165	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
GAN20_RS08175	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
GAN20_RS08190	COG0450	alkyl hydroperoxide reductase
GAN20_RS08195	COG0778	Nitroreductase
GAN20_RS08220	COG1823	symporter activity
GAN20_RS08225	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GAN20_RS08230	COG5183	chlorophyll binding
GAN20_RS08245	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GAN20_RS08250	COG2233	PERMEase
GAN20_RS08255	COG0516	GMP reductase activity
GAN20_RS08255	COG0517	IMP dehydrogenase activity
GAN20_RS08260	COG0519	Catalyzes the synthesis of GMP from XMP
GAN20_RS08260	COG0518	GMP synthase (glutamine-hydrolyzing) activity
GAN20_RS08295	COG1525	nuclease
GAN20_RS08315	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
GAN20_RS08340	COG0747	negative chemotaxis
GAN20_RS08345	COG0601	transmembrane transport
GAN20_RS08350	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GAN20_RS08355	COG0444	Belongs to the ABC transporter superfamily
GAN20_RS08360	COG1124	(ABC) transporter
GAN20_RS08375	COG2814	Major facilitator Superfamily
GAN20_RS08380	COG0730	response to heat
GAN20_RS08385	COG1937	Protein conserved in bacteria
GAN20_RS08390	COG2210	Belongs to the sulfur carrier protein TusA family
GAN20_RS08410	COG1263	PTS System
GAN20_RS08410	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GAN20_RS08415	COG1486	melibiose metabolic process
GAN20_RS08425	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
GAN20_RS08460	COG3682	Transcriptional regulator
GAN20_RS08480	COG3344	reverse transcriptase
GAN20_RS08495	COG0574	Belongs to the PEP-utilizing enzyme family
GAN20_RS08495	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GAN20_RS08500	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
GAN20_RS08515	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
GAN20_RS08520	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
GAN20_RS08530	COG2205	protein histidine kinase activity
GAN20_RS08535	COG0745	RESPONSE REGULATOR receiver
GAN20_RS08545	COG0733	neurotransmitter:sodium symporter activity
GAN20_RS08550	COG2272	Belongs to the type-B carboxylesterase lipase family
GAN20_RS08555	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
GAN20_RS08560	COG0626	cystathionine gamma-synthase activity
GAN20_RS08565	COG3344	reverse transcriptase
GAN20_RS08590	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
GAN20_RS08605	COG0583	DNA-binding transcription factor activity
GAN20_RS08610	COG0070	glutamate synthase
GAN20_RS08610	COG0069	glutamate synthase activity
GAN20_RS08610	COG0067	glutamate synthase
GAN20_RS08615	COG0493	'glutamate synthase
GAN20_RS08625	COG1263	PTS System
GAN20_RS08625	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GAN20_RS08630	COG0366	Alpha amylase catalytic
GAN20_RS08635	COG2188	Transcriptional regulator
GAN20_RS08645	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
GAN20_RS08650	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
GAN20_RS08655	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
GAN20_RS08660	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
GAN20_RS08685	COG1982	Orn Lys Arg decarboxylase major
GAN20_RS08690	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
GAN20_RS08695	COG3870	Protein conserved in bacteria
GAN20_RS08700	COG0470	DNA polymerase III
GAN20_RS08705	COG1774	PSP1 C-terminal conserved region
GAN20_RS08710	COG4467	Involved in initiation control of chromosome replication
GAN20_RS08715	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
GAN20_RS08720	COG2827	Endonuclease containing a URI domain
GAN20_RS08725	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
GAN20_RS08735	COG0084	hydrolase, TatD family'
GAN20_RS08740	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
GAN20_RS08750	COG4466	Protein conserved in bacteria
GAN20_RS08755	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
GAN20_RS08760	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GAN20_RS08765	COG0251	oxidation-reduction process
GAN20_RS08770	COG2088	sporulation resulting in formation of a cellular spore
GAN20_RS08775	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
GAN20_RS08780	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GAN20_RS08790	COG0193	aminoacyl-tRNA hydrolase activity
GAN20_RS08795	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
GAN20_RS08800	COG2244	polysaccharide biosynthetic process
GAN20_RS08805	COG3956	TIGRFAM MazG family protein
GAN20_RS08810	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
GAN20_RS08820	COG1098	S1 RNA binding domain
GAN20_RS08835	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GAN20_RS08840	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
GAN20_RS08850	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
GAN20_RS08860	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
GAN20_RS08865	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GAN20_RS08955	COG1289	transmembrane transporter activity
GAN20_RS08960	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GAN20_RS08965	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
GAN20_RS08970	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
GAN20_RS08980	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GAN20_RS08990	COG3880	PFAM UvrB UvrC protein
GAN20_RS08995	COG3869	Catalyzes the specific phosphorylation of arginine residues in
GAN20_RS09000	COG0542	response to heat
GAN20_RS09035	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
GAN20_RS09040	COG4956	integral membrane protein (PIN domain superfamily)
GAN20_RS09045	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
GAN20_RS09055	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GAN20_RS09060	COG1045	serine acetyltransferase
GAN20_RS09065	COG0215	cysteine-tRNA ligase activity
GAN20_RS09070	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
GAN20_RS09090	COG0267	Belongs to the bacterial ribosomal protein bL33 family
GAN20_RS09095	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
GAN20_RS09100	COG0250	Participates in transcription elongation, termination and antitermination
GAN20_RS09105	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
GAN20_RS09110	COG0081	regulation of translation
GAN20_RS09115	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
GAN20_RS09125	COG2813	Specifically methylates the guanine in position
GAN20_RS09130	COG0085	RNA polymerase activity
GAN20_RS09135	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GAN20_RS09145	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
GAN20_RS09150	COG0049	tRNA binding
GAN20_RS09155	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
GAN20_RS09160	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
GAN20_RS09165	COG3527	Alpha-acetolactate decarboxylase
GAN20_RS09170	COG1473	amidohydrolase
GAN20_RS09180	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GAN20_RS09210	COG0546	phosphoglycolate phosphatase activity
GAN20_RS09215	COG1428	Deoxynucleoside kinase
GAN20_RS09220	COG1428	Deoxynucleoside kinase
GAN20_RS09230	COG0561	phosphatase activity
GAN20_RS09245	COG0577	efflux transmembrane transporter activity
GAN20_RS09245	COG1136	(ABC) transporter
GAN20_RS09295	COG1469	GTP cyclohydrolase I activity
GAN20_RS09300	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
GAN20_RS09315	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GAN20_RS09315	COG1263	PTS System
GAN20_RS09315	COG2190	(PTS) system
GAN20_RS09330	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
GAN20_RS09340	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GAN20_RS09345	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
GAN20_RS09350	COG0588	phosphoglycerate mutase activity
GAN20_RS09355	COG0318	PFAM AMP-dependent synthetase and ligase
GAN20_RS09360	COG0183	Belongs to the thiolase family
GAN20_RS09390	COG2363	Small membrane protein
GAN20_RS09415	COG1566	PFAM secretion protein HlyD family protein
GAN20_RS09420	COG2814	Major facilitator Superfamily
GAN20_RS09430	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
GAN20_RS09435	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GAN20_RS09440	COG0095	Lipoate-protein ligase
GAN20_RS09445	COG0280	phosphate acetyltransferase
GAN20_RS09475	COG0471	metal ion transport
GAN20_RS09535	COG4844	belongs to the
GAN20_RS09545	COG1078	dGTPase activity
GAN20_RS09560	COG0018	arginyl-trna synthetase
GAN20_RS09565	COG0805	protein transport
GAN20_RS09570	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GAN20_RS09575	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GAN20_RS09580	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GAN20_RS09585	COG0546	phosphoglycolate phosphatase activity
GAN20_RS09635	COG2111	Na H antiporter
GAN20_RS09635	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
GAN20_RS09640	COG2111	Na H antiporter
GAN20_RS09645	COG1006	Multisubunit Na H antiporter MnhC subunit
GAN20_RS09655	COG1863	multisubunit Na H antiporter MnhE subunit
GAN20_RS09660	COG2212	antiporter activity
GAN20_RS09665	COG1320	monovalent cation:proton antiporter activity
GAN20_RS09670	COG0803	Belongs to the bacterial solute-binding protein 9 family
GAN20_RS09675	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GAN20_RS09680	COG1121	(ABC) transporter
GAN20_RS09690	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GAN20_RS09695	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GAN20_RS09700	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GAN20_RS09710	COG2423	ornithine cyclodeaminase activity
GAN20_RS09715	COG4264	IucA IucC family
GAN20_RS09720	COG2814	Major facilitator Superfamily
GAN20_RS09725	COG4264	IucA IucC family
GAN20_RS09730	COG4264	IucA IucC family
GAN20_RS09740	COG0019	diaminopimelate decarboxylase activity
GAN20_RS09745	COG1475	DNA binding
GAN20_RS09755	COG0110	maltose O-acetyltransferase activity
GAN20_RS09760	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
GAN20_RS09770	COG1682	transport, permease protein
GAN20_RS09775	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
GAN20_RS09780	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
GAN20_RS09800	COG1686	Belongs to the peptidase S11 family
GAN20_RS09805	COG1132	(ABC) transporter
GAN20_RS09825	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GAN20_RS09830	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GAN20_RS09835	COG1120	ATPase activity
GAN20_RS09840	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GAN20_RS09845	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GAN20_RS09855	COG0477	Major facilitator Superfamily
GAN20_RS09860	COG3949	Membrane
GAN20_RS09870	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GAN20_RS09875	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GAN20_RS09880	COG0745	RESPONSE REGULATOR receiver
GAN20_RS09890	COG1136	(ABC) transporter
GAN20_RS09895	COG0577	efflux transmembrane transporter activity
GAN20_RS09900	COG1392	Phosphate transport regulator
GAN20_RS09905	COG0306	phosphate transporter
GAN20_RS09910	COG1388	LysM domain
GAN20_RS09910	COG3942	CHAP domain
GAN20_RS09920	COG0352	thiamine-phosphate diphosphorylase activity
GAN20_RS09930	COG2022	thiamine diphosphate biosynthetic process
GAN20_RS09935	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
GAN20_RS09940	COG0217	transcriptional regulatory protein
GAN20_RS09955	COG0583	DNA-binding transcription factor activity
GAN20_RS09960	COG2814	Major facilitator Superfamily
GAN20_RS09965	COG2839	Protein conserved in bacteria
GAN20_RS09995	COG1611	Belongs to the LOG family
GAN20_RS10000	COG1671	Belongs to the UPF0178 family
GAN20_RS10010	COG1968	undecaprenyl-diphosphatase activity
GAN20_RS10015	COG4988	ABC transporter
GAN20_RS10020	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
GAN20_RS10035	COG0523	cobalamin synthesis protein
GAN20_RS10040	COG4989	oxidoreductase activity
GAN20_RS10055	COG0039	L-malate dehydrogenase activity
GAN20_RS10080	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
GAN20_RS10085	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
GAN20_RS10105	COG1349	DNA-binding transcription factor activity
GAN20_RS10110	COG1105	Belongs to the carbohydrate kinase PfkB family
GAN20_RS10115	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GAN20_RS10115	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GAN20_RS10115	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GAN20_RS10120	COG1253	flavin adenine dinucleotide binding
GAN20_RS10125	COG0463	Glycosyl transferase, family 2
GAN20_RS10140	COG0602	queuosine metabolic process
GAN20_RS10145	COG0720	synthase
GAN20_RS10155	COG0512	Glutamine amidotransferase of anthranilate synthase
GAN20_RS10175	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
GAN20_RS10185	COG1368	sulfuric ester hydrolase activity
GAN20_RS10195	COG0463	Glycosyl transferase, family 2
GAN20_RS10210	COG2274	protein secretion by the type I secretion system
GAN20_RS10220	COG0488	(ABC) transporter
GAN20_RS10225	COG0514	ATP-dependent DNA helicase (RecQ)
GAN20_RS10230	COG1125	glycine betaine transport
GAN20_RS10230	COG0517	IMP dehydrogenase activity
GAN20_RS10235	COG1174	glycine betaine transport
GAN20_RS10240	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
GAN20_RS10255	COG3104	oligopeptide transport
GAN20_RS10260	COG3104	oligopeptide transport
GAN20_RS10295	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GAN20_RS10300	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GAN20_RS10310	COG0812	UDP-N-acetylmuramate dehydrogenase activity
GAN20_RS10325	COG3118	belongs to the thioredoxin family
GAN20_RS10330	COG1929	Belongs to the glycerate kinase type-1 family
GAN20_RS10335	COG2195	Cleaves the N-terminal amino acid of tripeptides
GAN20_RS10355	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GAN20_RS10360	COG1739	Uncharacterized protein family UPF0029
GAN20_RS10370	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
GAN20_RS10385	COG0653	protein targeting
GAN20_RS10420	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
GAN20_RS10425	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
GAN20_RS10430	COG0110	maltose O-acetyltransferase activity
GAN20_RS10445	COG1660	Displays ATPase and GTPase activities
GAN20_RS10450	COG0391	Required for morphogenesis under gluconeogenic growth conditions
GAN20_RS10455	COG1481	regulation of sporulation
GAN20_RS10470	COG0740	serine-type endopeptidase activity
GAN20_RS10480	COG1090	epimerase
GAN20_RS10505	COG0126	phosphoglycerate kinase activity
GAN20_RS10510	COG0149	triose-phosphate isomerase activity
GAN20_RS10515	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
GAN20_RS10520	COG0148	phosphopyruvate hydratase activity
GAN20_RS10545	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
GAN20_RS10550	COG1647	Serine aminopeptidase, S33
GAN20_RS10555	COG0557	exoribonuclease II activity
GAN20_RS10585	COG0346	lactoylglutathione lyase activity
GAN20_RS10605	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
GAN20_RS10620	COG1764	response to oxidative stress
GAN20_RS10630	COG0710	3-dehydroquinate dehydratase activity
GAN20_RS10640	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GAN20_RS10645	COG1393	Belongs to the ArsC family
GAN20_RS10655	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
GAN20_RS10660	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GAN20_RS10670	COG2011	ABC-type metal ion transport system permease component
GAN20_RS10675	COG1464	Belongs to the NlpA lipoprotein family
GAN20_RS10680	COG1464	Belongs to the NlpA lipoprotein family
GAN20_RS10695	COG0396	ATPase activity
GAN20_RS10700	COG0719	Fe-S assembly protein
GAN20_RS10710	COG0822	iron-sulfur transferase activity
GAN20_RS10715	COG0719	Fe-S assembly protein
GAN20_RS10725	COG1253	flavin adenine dinucleotide binding
GAN20_RS10740	COG1801	Protein of unknown function DUF72
GAN20_RS10745	COG0730	response to heat
GAN20_RS10750	COG0737	Belongs to the 5'-nucleotidase family
GAN20_RS10755	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
GAN20_RS10760	COG4470	Protein conserved in bacteria
GAN20_RS10770	COG2445	Protein of unknown function DUF86
GAN20_RS10775	COG0647	UMP catabolic process
GAN20_RS10780	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GAN20_RS10785	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
GAN20_RS10790	COG4837	Protein of unknown function (DUF1462)
GAN20_RS10795	COG1252	NADH dehydrogenase
GAN20_RS10800	COG4844	belongs to the
GAN20_RS10805	COG0316	Belongs to the HesB IscA family
GAN20_RS10810	COG1252	NADH dehydrogenase
GAN20_RS10815	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
GAN20_RS10820	COG2056	Na+-H+ antiporter family
GAN20_RS10830	COG1320	monovalent cation:proton antiporter activity
GAN20_RS10835	COG2212	antiporter activity
GAN20_RS10840	COG1863	multisubunit Na H antiporter MnhE subunit
GAN20_RS10845	COG0651	ATP synthesis coupled electron transport
GAN20_RS10850	COG1006	Multisubunit Na H antiporter MnhC subunit
GAN20_RS10855	COG2111	Na H antiporter
GAN20_RS10860	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
GAN20_RS10860	COG2111	Na H antiporter
GAN20_RS10870	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GAN20_RS10890	COG1278	Cold shock
GAN20_RS10900	COG1098	S1 RNA binding domain
GAN20_RS10905	COG1012	belongs to the aldehyde dehydrogenase family
GAN20_RS10920	COG0584	glycerophosphoryl diester phosphodiesterase
GAN20_RS10930	COG0137	argininosuccinate synthase activity
GAN20_RS10935	COG0166	Belongs to the GPI family
GAN20_RS10950	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
GAN20_RS10960	COG0179	Fumarylacetoacetate (FAA) hydrolase
GAN20_RS10970	COG0446	pyridine nucleotide-disulphide oxidoreductase
GAN20_RS10975	COG0561	phosphatase activity
GAN20_RS11000	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
GAN20_RS11025	COG0601	transmembrane transport
GAN20_RS11030	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GAN20_RS11035	COG0444	Belongs to the ABC transporter superfamily
GAN20_RS11040	COG4608	Belongs to the ABC transporter superfamily
GAN20_RS11045	COG4166	transmembrane transport
GAN20_RS11050	COG0180	Tryptophanyl-tRNA synthetase
GAN20_RS11055	COG1393	Belongs to the ArsC family
GAN20_RS11080	COG1164	Oligoendopeptidase f
GAN20_RS11090	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
GAN20_RS11095	COG2346	COG2346, Truncated hemoglobins
GAN20_RS11110	COG2357	RelA SpoT domain protein
GAN20_RS11120	COG0564	pseudouridine synthase activity
GAN20_RS11125	COG2239	Acts as a magnesium transporter
GAN20_RS11130	COG0569	domain protein
GAN20_RS11130	COG0475	glutathione-regulated potassium exporter activity
GAN20_RS11140	COG0628	permease
GAN20_RS11145	COG1115	amino acid carrier protein
GAN20_RS11150	COG2382	esterase
GAN20_RS11155	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
GAN20_RS11185	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
GAN20_RS11220	COG3716	PTS system mannose fructose sorbose family IID component
GAN20_RS11225	COG3715	PTS system
GAN20_RS11235	COG2814	Major facilitator Superfamily
GAN20_RS11240	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
GAN20_RS11245	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
GAN20_RS11255	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
GAN20_RS11260	COG0861	Integral membrane protein TerC family
GAN20_RS11265	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GAN20_RS11270	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GAN20_RS11275	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
GAN20_RS11285	COG1696	Membrane protein involved in D-alanine export
GAN20_RS11290	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GAN20_RS11300	COG0737	Belongs to the 5'-nucleotidase family
GAN20_RS11305	COG4932	domain protein
GAN20_RS11305	COG3266	domain, Protein
GAN20_RS11305	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
GAN20_RS11315	COG3344	reverse transcriptase
GAN20_RS11385	COG4873	Protein conserved in bacteria
GAN20_RS11405	COG4619	ABC transporter
GAN20_RS11410	COG0390	transport system, permease component
GAN20_RS11415	COG1575	Belongs to the MenA family. Type 1 subfamily
GAN20_RS11420	COG1169	isochorismate synthase
GAN20_RS11425	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
GAN20_RS11435	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
GAN20_RS11440	COG0436	Aminotransferase
GAN20_RS11445	COG3594	Acyltransferase
GAN20_RS11470	COG1316	TRANSCRIPTIONal
GAN20_RS11475	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GAN20_RS11480	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
GAN20_RS11490	COG1215	transferase activity, transferring glycosyl groups
GAN20_RS11500	COG1682	transport, permease protein
GAN20_RS11510	COG1134	teichoic acid transport
GAN20_RS11525	COG3212	peptidase
GAN20_RS11535	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
GAN20_RS11540	COG1845	cytochrome c oxidase, subunit III
GAN20_RS11550	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
GAN20_RS11560	COG1017	nitric oxide dioxygenase activity
GAN20_RS11560	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GAN20_RS11565	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
GAN20_RS11570	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
GAN20_RS11575	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
GAN20_RS11580	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
GAN20_RS11585	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GAN20_RS11590	COG0047	phosphoribosylformylglycinamidine synthase activity
GAN20_RS11600	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
GAN20_RS11605	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
GAN20_RS11615	COG0138	bifunctional purine biosynthesis protein purh
GAN20_RS11620	COG0151	Belongs to the GarS family
GAN20_RS11630	COG4172	Belongs to the ABC transporter superfamily
GAN20_RS11645	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
GAN20_RS11655	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GAN20_RS11660	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GAN20_RS11665	COG1393	Belongs to the ArsC family
GAN20_RS11670	COG1271	oxidase subunit
GAN20_RS11675	COG1294	oxidase, subunit
GAN20_RS11680	COG0569	domain protein
GAN20_RS11705	COG0492	ferredoxin-NADP+ reductase activity
GAN20_RS11710	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
GAN20_RS11715	COG5503	Protein of unknown function (DUF1447)
GAN20_RS11755	COG4476	Belongs to the UPF0223 family
GAN20_RS11765	COG3842	ATPase activity
GAN20_RS11775	COG1177	transmembrane transport
GAN20_RS11780	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
GAN20_RS11795	COG4493	Belongs to the UPF0637 family
GAN20_RS11800	COG0483	inositol monophosphate 1-phosphatase activity
GAN20_RS11810	COG1217	gtp-binding protein TYPA
GAN20_RS11815	COG1902	pentaerythritol trinitrate reductase activity
GAN20_RS11820	COG4896	Protein conserved in bacteria
GAN20_RS11825	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
GAN20_RS11830	COG4838	Belongs to the UPF0358 family
GAN20_RS11835	COG0772	Belongs to the SEDS family
GAN20_RS11840	COG3344	reverse transcriptase
GAN20_RS11845	COG3344	reverse transcriptase
GAN20_RS11865	COG0109	protoheme IX farnesyltransferase activity
GAN20_RS11880	COG3679	Belongs to the UPF0342 family
GAN20_RS11885	COG0584	glycerophosphoryl diester phosphodiesterase
GAN20_RS11890	COG4471	UPF0298 protein
GAN20_RS11900	COG0742	ribosomal rna small subunit methyltransferase
GAN20_RS11920	COG0333	Belongs to the bacterial ribosomal protein bL32 family
GAN20_RS11925	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GAN20_RS11930	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
GAN20_RS11945	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GAN20_RS11960	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
GAN20_RS11960	COG1796	DNA polymerase
GAN20_RS11965	COG1193	negative regulation of DNA recombination
GAN20_RS11970	COG3118	belongs to the thioredoxin family
GAN20_RS11975	COG0322	excinuclease ABC activity
GAN20_RS11980	COG2009	succinate dehydrogenase
GAN20_RS11985	COG1053	succinate dehydrogenase
GAN20_RS11990	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
GAN20_RS11995	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
GAN20_RS12055	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GAN20_RS12070	COG1011	Hydrolase
GAN20_RS12075	COG0454	-acetyltransferase
GAN20_RS12080	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
GAN20_RS12085	COG2001	Belongs to the MraZ family
GAN20_RS12090	COG0275	rRNA processing
GAN20_RS12095	COG4839	cell division protein FtsL
GAN20_RS12100	COG0768	penicillin binding
GAN20_RS12110	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
GAN20_RS12120	COG0849	cell division
GAN20_RS12125	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
GAN20_RS12135	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
GAN20_RS12140	COG1799	cell septum assembly
GAN20_RS12145	COG0762	integral membrane protein
GAN20_RS12150	COG1869	D-ribose catabolic process
GAN20_RS12155	COG4975	Glucose uptake
GAN20_RS12165	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GAN20_RS12170	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GAN20_RS12180	COG4409	exo-alpha-(2->6)-sialidase activity
GAN20_RS12185	COG0673	inositol 2-dehydrogenase activity
GAN20_RS12195	COG3599	regulation of cell shape
GAN20_RS12200	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
GAN20_RS12205	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
GAN20_RS12210	COG0564	pseudouridine synthase activity
GAN20_RS12215	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
GAN20_RS12235	COG0505	Belongs to the CarA family
GAN20_RS12240	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
GAN20_RS12250	COG0167	dihydroorotate dehydrogenase activity
GAN20_RS12255	COG0284	orotidine-5'-phosphate decarboxylase activity
GAN20_RS12260	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
GAN20_RS12280	COG1758	RNA polymerase activity
GAN20_RS12285	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
GAN20_RS12290	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
GAN20_RS12295	COG0242	peptide deformylase activity
GAN20_RS12300	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
GAN20_RS12305	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GAN20_RS12305	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GAN20_RS12310	COG0820	rRNA (adenine-C2-)-methyltransferase activity
GAN20_RS12325	COG2124	cytochrome p450
GAN20_RS12330	COG1162	GTPase activity
GAN20_RS12335	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
GAN20_RS12350	COG1302	Protein conserved in bacteria
GAN20_RS12360	COG1760	l-serine dehydratase
GAN20_RS12365	COG1760	l-serine dehydratase
GAN20_RS12375	COG1349	DNA-binding transcription factor activity
GAN20_RS12380	COG0416	fatty acid biosynthetic process
GAN20_RS12395	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GAN20_RS12400	COG0571	ribonuclease III activity
GAN20_RS12405	COG1196	nuclear chromosome segregation
GAN20_RS12410	COG0552	protein localization to endoplasmic reticulum
GAN20_RS12415	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
GAN20_RS12420	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GAN20_RS12435	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification