locus-tag	class	description
GAN21_RS00030	COG5503	Protein of unknown function (DUF1447)
GAN21_RS00035	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
GAN21_RS00040	COG0492	ferredoxin-NADP+ reductase activity
GAN21_RS00065	COG0569	domain protein
GAN21_RS00070	COG1294	oxidase, subunit
GAN21_RS00075	COG1271	oxidase subunit
GAN21_RS00080	COG1393	Belongs to the ArsC family
GAN21_RS00085	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GAN21_RS00090	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GAN21_RS00100	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
GAN21_RS00115	COG4172	Belongs to the ABC transporter superfamily
GAN21_RS00125	COG0151	Belongs to the GarS family
GAN21_RS00130	COG0138	bifunctional purine biosynthesis protein purh
GAN21_RS00140	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
GAN21_RS00145	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
GAN21_RS00155	COG0047	phosphoribosylformylglycinamidine synthase activity
GAN21_RS00160	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GAN21_RS00165	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
GAN21_RS00170	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
GAN21_RS00175	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
GAN21_RS00180	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
GAN21_RS00185	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GAN21_RS00185	COG1017	nitric oxide dioxygenase activity
GAN21_RS00195	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
GAN21_RS00205	COG1845	cytochrome c oxidase, subunit III
GAN21_RS00210	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
GAN21_RS00220	COG3212	peptidase
GAN21_RS00235	COG1134	teichoic acid transport
GAN21_RS00245	COG1682	transport, permease protein
GAN21_RS00255	COG1215	transferase activity, transferring glycosyl groups
GAN21_RS00265	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
GAN21_RS00270	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GAN21_RS00275	COG1316	TRANSCRIPTIONal
GAN21_RS00300	COG3594	Acyltransferase
GAN21_RS00305	COG0436	Aminotransferase
GAN21_RS00310	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
GAN21_RS00320	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
GAN21_RS00325	COG1169	isochorismate synthase
GAN21_RS00330	COG1575	Belongs to the MenA family. Type 1 subfamily
GAN21_RS00335	COG0390	transport system, permease component
GAN21_RS00340	COG4619	ABC transporter
GAN21_RS00360	COG4873	Protein conserved in bacteria
GAN21_RS00430	COG3344	reverse transcriptase
GAN21_RS00440	COG4932	domain protein
GAN21_RS00440	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
GAN21_RS00440	COG3266	domain, Protein
GAN21_RS00445	COG0737	Belongs to the 5'-nucleotidase family
GAN21_RS00455	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GAN21_RS00460	COG1696	Membrane protein involved in D-alanine export
GAN21_RS00470	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
GAN21_RS00475	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GAN21_RS00480	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GAN21_RS00485	COG0861	Integral membrane protein TerC family
GAN21_RS00490	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
GAN21_RS00500	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
GAN21_RS00505	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
GAN21_RS00510	COG2814	Major facilitator Superfamily
GAN21_RS00520	COG3715	PTS system
GAN21_RS00525	COG3716	PTS system mannose fructose sorbose family IID component
GAN21_RS00560	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
GAN21_RS00590	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
GAN21_RS00595	COG2382	esterase
GAN21_RS00600	COG1115	amino acid carrier protein
GAN21_RS00605	COG0628	permease
GAN21_RS00615	COG0475	glutathione-regulated potassium exporter activity
GAN21_RS00615	COG0569	domain protein
GAN21_RS00620	COG2239	Acts as a magnesium transporter
GAN21_RS00625	COG0564	pseudouridine synthase activity
GAN21_RS00635	COG2357	RelA SpoT domain protein
GAN21_RS00650	COG2346	COG2346, Truncated hemoglobins
GAN21_RS00655	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
GAN21_RS00665	COG1164	Oligoendopeptidase f
GAN21_RS00690	COG1393	Belongs to the ArsC family
GAN21_RS00695	COG0180	Tryptophanyl-tRNA synthetase
GAN21_RS00700	COG4166	transmembrane transport
GAN21_RS00705	COG4608	Belongs to the ABC transporter superfamily
GAN21_RS00710	COG0444	Belongs to the ABC transporter superfamily
GAN21_RS00715	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GAN21_RS00720	COG0601	transmembrane transport
GAN21_RS00745	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
GAN21_RS00770	COG0561	phosphatase activity
GAN21_RS00775	COG0446	pyridine nucleotide-disulphide oxidoreductase
GAN21_RS00785	COG0179	Fumarylacetoacetate (FAA) hydrolase
GAN21_RS00795	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
GAN21_RS00810	COG0166	Belongs to the GPI family
GAN21_RS00815	COG0137	argininosuccinate synthase activity
GAN21_RS00825	COG0584	glycerophosphoryl diester phosphodiesterase
GAN21_RS00840	COG1012	belongs to the aldehyde dehydrogenase family
GAN21_RS00845	COG1098	S1 RNA binding domain
GAN21_RS00855	COG1278	Cold shock
GAN21_RS00875	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GAN21_RS00885	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
GAN21_RS00885	COG2111	Na H antiporter
GAN21_RS00890	COG2111	Na H antiporter
GAN21_RS00895	COG1006	Multisubunit Na H antiporter MnhC subunit
GAN21_RS00900	COG0651	ATP synthesis coupled electron transport
GAN21_RS00905	COG1863	multisubunit Na H antiporter MnhE subunit
GAN21_RS00910	COG2212	antiporter activity
GAN21_RS00915	COG1320	monovalent cation:proton antiporter activity
GAN21_RS00925	COG2056	Na+-H+ antiporter family
GAN21_RS00930	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
GAN21_RS00935	COG1252	NADH dehydrogenase
GAN21_RS00940	COG0316	Belongs to the HesB IscA family
GAN21_RS00945	COG4844	belongs to the
GAN21_RS00950	COG1252	NADH dehydrogenase
GAN21_RS00955	COG4837	Protein of unknown function (DUF1462)
GAN21_RS00960	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
GAN21_RS00965	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GAN21_RS00970	COG0647	UMP catabolic process
GAN21_RS00975	COG2445	Protein of unknown function DUF86
GAN21_RS00985	COG4470	Protein conserved in bacteria
GAN21_RS00990	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
GAN21_RS00995	COG0737	Belongs to the 5'-nucleotidase family
GAN21_RS01000	COG0730	response to heat
GAN21_RS01005	COG1801	Protein of unknown function DUF72
GAN21_RS01020	COG1253	flavin adenine dinucleotide binding
GAN21_RS01030	COG0719	Fe-S assembly protein
GAN21_RS01035	COG0822	iron-sulfur transferase activity
GAN21_RS01045	COG0719	Fe-S assembly protein
GAN21_RS01050	COG0396	ATPase activity
GAN21_RS01065	COG1464	Belongs to the NlpA lipoprotein family
GAN21_RS01070	COG1464	Belongs to the NlpA lipoprotein family
GAN21_RS01075	COG2011	ABC-type metal ion transport system permease component
GAN21_RS01085	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GAN21_RS01090	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
GAN21_RS01100	COG1393	Belongs to the ArsC family
GAN21_RS01105	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GAN21_RS01115	COG0710	3-dehydroquinate dehydratase activity
GAN21_RS01125	COG1764	response to oxidative stress
GAN21_RS01140	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
GAN21_RS01160	COG0346	lactoylglutathione lyase activity
GAN21_RS01190	COG0557	exoribonuclease II activity
GAN21_RS01195	COG1647	Serine aminopeptidase, S33
GAN21_RS01200	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
GAN21_RS01225	COG0148	phosphopyruvate hydratase activity
GAN21_RS01230	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
GAN21_RS01235	COG0149	triose-phosphate isomerase activity
GAN21_RS01240	COG0126	phosphoglycerate kinase activity
GAN21_RS01265	COG1090	epimerase
GAN21_RS01275	COG0740	serine-type endopeptidase activity
GAN21_RS01290	COG1481	regulation of sporulation
GAN21_RS01295	COG0391	Required for morphogenesis under gluconeogenic growth conditions
GAN21_RS01300	COG1660	Displays ATPase and GTPase activities
GAN21_RS01315	COG0110	maltose O-acetyltransferase activity
GAN21_RS01320	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
GAN21_RS01325	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
GAN21_RS01360	COG0653	protein targeting
GAN21_RS01375	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
GAN21_RS01385	COG1739	Uncharacterized protein family UPF0029
GAN21_RS01390	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GAN21_RS01410	COG2195	Cleaves the N-terminal amino acid of tripeptides
GAN21_RS01415	COG1929	Belongs to the glycerate kinase type-1 family
GAN21_RS01420	COG3118	belongs to the thioredoxin family
GAN21_RS01435	COG0812	UDP-N-acetylmuramate dehydrogenase activity
GAN21_RS01445	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GAN21_RS01450	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GAN21_RS01485	COG3104	oligopeptide transport
GAN21_RS01490	COG3104	oligopeptide transport
GAN21_RS01505	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
GAN21_RS01510	COG1174	glycine betaine transport
GAN21_RS01515	COG0517	IMP dehydrogenase activity
GAN21_RS01515	COG1125	glycine betaine transport
GAN21_RS01520	COG0514	ATP-dependent DNA helicase (RecQ)
GAN21_RS01525	COG0488	(ABC) transporter
GAN21_RS01535	COG2274	protein secretion by the type I secretion system
GAN21_RS01550	COG0463	Glycosyl transferase, family 2
GAN21_RS01560	COG1368	sulfuric ester hydrolase activity
GAN21_RS01570	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
GAN21_RS01590	COG0512	Glutamine amidotransferase of anthranilate synthase
GAN21_RS01600	COG0720	synthase
GAN21_RS01605	COG0602	queuosine metabolic process
GAN21_RS01620	COG0463	Glycosyl transferase, family 2
GAN21_RS01625	COG1253	flavin adenine dinucleotide binding
GAN21_RS01630	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GAN21_RS01630	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GAN21_RS01630	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GAN21_RS01635	COG1105	Belongs to the carbohydrate kinase PfkB family
GAN21_RS01640	COG1349	DNA-binding transcription factor activity
GAN21_RS01660	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
GAN21_RS01665	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
GAN21_RS01690	COG0039	L-malate dehydrogenase activity
GAN21_RS01705	COG4989	oxidoreductase activity
GAN21_RS01710	COG0523	cobalamin synthesis protein
GAN21_RS01725	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
GAN21_RS01730	COG4988	ABC transporter
GAN21_RS01735	COG1968	undecaprenyl-diphosphatase activity
GAN21_RS01745	COG1671	Belongs to the UPF0178 family
GAN21_RS01750	COG1611	Belongs to the LOG family
GAN21_RS01780	COG2839	Protein conserved in bacteria
GAN21_RS01785	COG2814	Major facilitator Superfamily
GAN21_RS01790	COG0583	DNA-binding transcription factor activity
GAN21_RS01805	COG0217	transcriptional regulatory protein
GAN21_RS01810	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
GAN21_RS01815	COG2022	thiamine diphosphate biosynthetic process
GAN21_RS01825	COG0352	thiamine-phosphate diphosphorylase activity
GAN21_RS01835	COG3942	CHAP domain
GAN21_RS01835	COG1388	LysM domain
GAN21_RS01840	COG0306	phosphate transporter
GAN21_RS01845	COG1392	Phosphate transport regulator
GAN21_RS01850	COG0577	efflux transmembrane transporter activity
GAN21_RS01855	COG1136	(ABC) transporter
GAN21_RS01865	COG0745	RESPONSE REGULATOR receiver
GAN21_RS01870	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GAN21_RS01875	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GAN21_RS01885	COG3949	Membrane
GAN21_RS01890	COG0477	Major facilitator Superfamily
GAN21_RS01900	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GAN21_RS01905	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GAN21_RS01910	COG1120	ATPase activity
GAN21_RS01915	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GAN21_RS01920	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GAN21_RS01940	COG1132	(ABC) transporter
GAN21_RS01945	COG1686	Belongs to the peptidase S11 family
GAN21_RS01965	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
GAN21_RS01970	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
GAN21_RS01975	COG1682	transport, permease protein
GAN21_RS01985	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
GAN21_RS01990	COG0110	maltose O-acetyltransferase activity
GAN21_RS02000	COG1475	DNA binding
GAN21_RS02005	COG0019	diaminopimelate decarboxylase activity
GAN21_RS02015	COG4264	IucA IucC family
GAN21_RS02020	COG4264	IucA IucC family
GAN21_RS02025	COG2814	Major facilitator Superfamily
GAN21_RS02030	COG4264	IucA IucC family
GAN21_RS02035	COG2423	ornithine cyclodeaminase activity
GAN21_RS02045	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GAN21_RS02050	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GAN21_RS02055	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GAN21_RS02065	COG1121	(ABC) transporter
GAN21_RS02070	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GAN21_RS02075	COG0803	Belongs to the bacterial solute-binding protein 9 family
GAN21_RS02080	COG1320	monovalent cation:proton antiporter activity
GAN21_RS02085	COG2212	antiporter activity
GAN21_RS02090	COG1863	multisubunit Na H antiporter MnhE subunit
GAN21_RS02100	COG1006	Multisubunit Na H antiporter MnhC subunit
GAN21_RS02105	COG2111	Na H antiporter
GAN21_RS02110	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
GAN21_RS02110	COG2111	Na H antiporter
GAN21_RS02160	COG0546	phosphoglycolate phosphatase activity
GAN21_RS02165	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GAN21_RS02170	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GAN21_RS02175	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GAN21_RS02180	COG0805	protein transport
GAN21_RS02185	COG0018	arginyl-trna synthetase
GAN21_RS02200	COG1078	dGTPase activity
GAN21_RS02210	COG4844	belongs to the
GAN21_RS02270	COG0471	metal ion transport
GAN21_RS02300	COG0280	phosphate acetyltransferase
GAN21_RS02305	COG0095	Lipoate-protein ligase
GAN21_RS02310	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GAN21_RS02315	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
GAN21_RS02325	COG2814	Major facilitator Superfamily
GAN21_RS02330	COG1566	PFAM secretion protein HlyD family protein
GAN21_RS02355	COG2363	Small membrane protein
GAN21_RS02385	COG0183	Belongs to the thiolase family
GAN21_RS02390	COG0318	PFAM AMP-dependent synthetase and ligase
GAN21_RS02395	COG0588	phosphoglycerate mutase activity
GAN21_RS02400	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
GAN21_RS02405	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GAN21_RS02415	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
GAN21_RS02430	COG1263	PTS System
GAN21_RS02430	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GAN21_RS02430	COG2190	(PTS) system
GAN21_RS02445	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
GAN21_RS02450	COG1469	GTP cyclohydrolase I activity
GAN21_RS02500	COG0577	efflux transmembrane transporter activity
GAN21_RS02500	COG1136	(ABC) transporter
GAN21_RS02515	COG0561	phosphatase activity
GAN21_RS02525	COG1428	Deoxynucleoside kinase
GAN21_RS02530	COG1428	Deoxynucleoside kinase
GAN21_RS02535	COG0546	phosphoglycolate phosphatase activity
GAN21_RS02565	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GAN21_RS02575	COG1473	amidohydrolase
GAN21_RS02580	COG3527	Alpha-acetolactate decarboxylase
GAN21_RS02585	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
GAN21_RS02590	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
GAN21_RS02595	COG0049	tRNA binding
GAN21_RS02600	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
GAN21_RS02610	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GAN21_RS02615	COG0085	RNA polymerase activity
GAN21_RS02620	COG2813	Specifically methylates the guanine in position
GAN21_RS02630	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
GAN21_RS02635	COG0081	regulation of translation
GAN21_RS02640	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
GAN21_RS02645	COG0250	Participates in transcription elongation, termination and antitermination
GAN21_RS02650	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
GAN21_RS02655	COG0267	Belongs to the bacterial ribosomal protein bL33 family
GAN21_RS02675	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
GAN21_RS02680	COG0215	cysteine-tRNA ligase activity
GAN21_RS02685	COG1045	serine acetyltransferase
GAN21_RS02690	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GAN21_RS02700	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
GAN21_RS02705	COG4956	integral membrane protein (PIN domain superfamily)
GAN21_RS02710	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
GAN21_RS02745	COG0542	response to heat
GAN21_RS02750	COG3869	Catalyzes the specific phosphorylation of arginine residues in
GAN21_RS02755	COG3880	PFAM UvrB UvrC protein
GAN21_RS02765	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GAN21_RS02775	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
GAN21_RS02780	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
GAN21_RS02785	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GAN21_RS02790	COG1289	transmembrane transporter activity
GAN21_RS02880	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GAN21_RS02885	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
GAN21_RS02895	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
GAN21_RS02905	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
GAN21_RS02910	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GAN21_RS02925	COG1098	S1 RNA binding domain
GAN21_RS02935	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
GAN21_RS02940	COG3956	TIGRFAM MazG family protein
GAN21_RS02945	COG2244	polysaccharide biosynthetic process
GAN21_RS02950	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
GAN21_RS02955	COG0193	aminoacyl-tRNA hydrolase activity
GAN21_RS02965	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GAN21_RS02970	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
GAN21_RS02975	COG2088	sporulation resulting in formation of a cellular spore
GAN21_RS02980	COG0251	oxidation-reduction process
GAN21_RS02985	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GAN21_RS02990	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
GAN21_RS02995	COG4466	Protein conserved in bacteria
GAN21_RS03005	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
GAN21_RS03010	COG0084	hydrolase, TatD family'
GAN21_RS03020	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
GAN21_RS03025	COG2827	Endonuclease containing a URI domain
GAN21_RS03030	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
GAN21_RS03035	COG4467	Involved in initiation control of chromosome replication
GAN21_RS03040	COG1774	PSP1 C-terminal conserved region
GAN21_RS03045	COG0470	DNA polymerase III
GAN21_RS03050	COG3870	Protein conserved in bacteria
GAN21_RS03055	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
GAN21_RS03060	COG1982	Orn Lys Arg decarboxylase major
GAN21_RS03085	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
GAN21_RS03090	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
GAN21_RS03095	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
GAN21_RS03100	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
GAN21_RS03110	COG2188	Transcriptional regulator
GAN21_RS03115	COG0366	Alpha amylase catalytic
GAN21_RS03120	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GAN21_RS03120	COG1263	PTS System
GAN21_RS03130	COG0493	'glutamate synthase
GAN21_RS03135	COG0070	glutamate synthase
GAN21_RS03135	COG0069	glutamate synthase activity
GAN21_RS03135	COG0067	glutamate synthase
GAN21_RS03140	COG0583	DNA-binding transcription factor activity
GAN21_RS03155	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
GAN21_RS03180	COG3344	reverse transcriptase
GAN21_RS03185	COG0626	cystathionine gamma-synthase activity
GAN21_RS03190	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
GAN21_RS03195	COG2272	Belongs to the type-B carboxylesterase lipase family
GAN21_RS03200	COG0733	neurotransmitter:sodium symporter activity
GAN21_RS03210	COG0745	RESPONSE REGULATOR receiver
GAN21_RS03215	COG2205	protein histidine kinase activity
GAN21_RS03225	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
GAN21_RS03230	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
GAN21_RS03245	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
GAN21_RS03250	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GAN21_RS03250	COG0574	Belongs to the PEP-utilizing enzyme family
GAN21_RS03265	COG3344	reverse transcriptase
GAN21_RS03285	COG3682	Transcriptional regulator
GAN21_RS03320	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
GAN21_RS03330	COG1486	melibiose metabolic process
GAN21_RS03335	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GAN21_RS03335	COG1263	PTS System
GAN21_RS03355	COG2210	Belongs to the sulfur carrier protein TusA family
GAN21_RS03360	COG1937	Protein conserved in bacteria
GAN21_RS03365	COG0730	response to heat
GAN21_RS03370	COG2814	Major facilitator Superfamily
GAN21_RS03385	COG1124	(ABC) transporter
GAN21_RS03390	COG0444	Belongs to the ABC transporter superfamily
GAN21_RS03395	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GAN21_RS03400	COG0601	transmembrane transport
GAN21_RS03405	COG0747	negative chemotaxis
GAN21_RS03430	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
GAN21_RS03450	COG1525	nuclease
GAN21_RS03485	COG0518	GMP synthase (glutamine-hydrolyzing) activity
GAN21_RS03485	COG0519	Catalyzes the synthesis of GMP from XMP
GAN21_RS03490	COG0516	GMP reductase activity
GAN21_RS03490	COG0517	IMP dehydrogenase activity
GAN21_RS03495	COG2233	PERMEase
GAN21_RS03500	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GAN21_RS03515	COG5183	chlorophyll binding
GAN21_RS03520	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GAN21_RS03525	COG1823	symporter activity
GAN21_RS03550	COG0778	Nitroreductase
GAN21_RS03555	COG0450	alkyl hydroperoxide reductase
GAN21_RS03570	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
GAN21_RS03580	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
GAN21_RS03585	COG2011	ABC-type metal ion transport system permease component
GAN21_RS03590	COG1464	Belongs to the NlpA lipoprotein family
GAN21_RS03595	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
GAN21_RS03600	COG0753	catalase activity
GAN21_RS03605	COG3842	ATPase activity
GAN21_RS03610	COG0673	inositol 2-dehydrogenase activity
GAN21_RS03615	COG0395	ABC-type sugar transport system, permease component
GAN21_RS03620	COG1175	transmembrane transport
GAN21_RS03630	COG2207	Transcriptional regulator
GAN21_RS03630	COG0662	Cupin 2, conserved barrel domain protein
GAN21_RS03635	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
GAN21_RS03645	COG0360	Binds together with S18 to 16S ribosomal RNA
GAN21_RS03655	COG1668	transmembrane transport
GAN21_RS03660	COG1131	(ABC) transporter
GAN21_RS03665	COG0012	GTP binding
GAN21_RS03670	COG4481	Protein conserved in bacteria
GAN21_RS03675	COG0668	transmembrane transport
GAN21_RS03680	COG1475	DNA binding
GAN21_RS03685	COG0626	cystathionine gamma-synthase activity
GAN21_RS03690	COG0626	cystathionine gamma-synthase activity
GAN21_RS03695	COG0646	methionine synthase
GAN21_RS03695	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
GAN21_RS03705	COG0829	nickel cation binding
GAN21_RS03715	COG0830	nickel cation binding
GAN21_RS03720	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
GAN21_RS03730	COG2388	GCN5-related N-acetyl-transferase
GAN21_RS03735	COG1846	Transcriptional regulator
GAN21_RS03740	COG0346	lactoylglutathione lyase activity
GAN21_RS03745	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GAN21_RS03750	COG0400	carboxylic ester hydrolase activity
GAN21_RS03775	COG0357	Ribosomal RNA small subunit methyltransferase G
GAN21_RS03780	COG0445	tRNA wobble uridine modification
GAN21_RS03785	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
GAN21_RS03790	COG0594	ribonuclease P activity
GAN21_RS03800	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
GAN21_RS03805	COG0592	DNA-directed DNA polymerase activity
GAN21_RS03810	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
GAN21_RS03810	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
GAN21_RS03815	COG2501	S4 domain
GAN21_RS03820	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
GAN21_RS03825	COG0187	DNA topoisomerase II activity
GAN21_RS03835	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
GAN21_RS03840	COG2986	histidine ammonia-lyase
GAN21_RS03850	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
GAN21_RS03860	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
GAN21_RS03865	COG4241	membrane
GAN21_RS03870	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
GAN21_RS03875	COG0359	binds to the 23S rRNA
GAN21_RS03885	COG0305	Participates in initiation and elongation during chromosome replication
GAN21_RS03890	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
GAN21_RS03895	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GAN21_RS03915	COG0745	RESPONSE REGULATOR receiver
GAN21_RS03920	COG5002	protein histidine kinase activity
GAN21_RS03925	COG4863	YycH protein
GAN21_RS03935	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
GAN21_RS03940	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
GAN21_RS03950	COG3425	synthase
GAN21_RS03960	COG0584	glycerophosphoryl diester phosphodiesterase
GAN21_RS03965	COG2030	dehydratase
GAN21_RS03990	COG1846	Transcriptional regulator
GAN21_RS03990	COG1940	carbohydrate kinase activity
GAN21_RS04000	COG2210	Belongs to the sulfur carrier protein TusA family
GAN21_RS04005	COG1937	Protein conserved in bacteria
GAN21_RS04010	COG0730	response to heat
GAN21_RS04040	COG0785	Cytochrome C biogenesis protein
GAN21_RS04055	COG3682	Transcriptional regulator
GAN21_RS04060	COG1388	LysM domain
GAN21_RS04065	COG5002	protein histidine kinase activity
GAN21_RS04070	COG0745	RESPONSE REGULATOR receiver
GAN21_RS04080	COG2132	Multicopper oxidase
GAN21_RS04095	COG2311	Membrane
GAN21_RS04115	COG0531	amino acid
GAN21_RS04120	COG2217	Heavy metal translocating P-type atpase
GAN21_RS04135	COG3655	Transcriptional regulator
GAN21_RS04150	COG2188	Transcriptional regulator
GAN21_RS04155	COG2723	6-phospho-beta-galactosidase activity
GAN21_RS04165	COG0415	Belongs to the DNA photolyase family
GAN21_RS04180	COG0702	epimerase
GAN21_RS04185	COG2130	NADP-dependent
GAN21_RS04200	COG3177	Filamentation induced by cAMP protein fic
GAN21_RS04205	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GAN21_RS04215	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
GAN21_RS04220	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GAN21_RS04240	COG2235	arginine
GAN21_RS04255	COG2197	response regulator
GAN21_RS04260	COG4585	Histidine kinase
GAN21_RS04260	COG2203	Gaf domain
GAN21_RS04265	COG0842	Transport permease protein
GAN21_RS04270	COG1131	(ABC) transporter
GAN21_RS04290	COG0431	NADPH-dependent FMN reductase
GAN21_RS04295	COG4932	domain protein
GAN21_RS04295	COG3583	domain protein
GAN21_RS04295	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
GAN21_RS04315	COG1609	Transcriptional regulator
GAN21_RS04325	COG0673	inositol 2-dehydrogenase activity
GAN21_RS04335	COG0366	Alpha amylase catalytic
GAN21_RS04345	COG3833	ABC-type maltose transport systems, permease component
GAN21_RS04350	COG1175	transmembrane transport
GAN21_RS04360	COG3842	ATPase activity
GAN21_RS04365	COG0475	glutathione-regulated potassium exporter activity
GAN21_RS04370	COG0490	domain, Protein
GAN21_RS04380	COG0346	lactoylglutathione lyase activity
GAN21_RS04415	COG1131	(ABC) transporter
GAN21_RS04425	COG0366	Alpha amylase catalytic
GAN21_RS04430	COG2188	Transcriptional regulator
GAN21_RS04435	COG2222	sugar isomerase
GAN21_RS04440	COG1105	Belongs to the carbohydrate kinase PfkB family
GAN21_RS04455	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GAN21_RS04455	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
GAN21_RS04460	COG3715	PTS system
GAN21_RS04465	COG3716	PTS system mannose fructose sorbose family IID component
GAN21_RS04475	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
GAN21_RS04495	COG3314	Sporulation integral membrane protein YlbJ
GAN21_RS04515	COG1063	alcohol dehydrogenase
GAN21_RS04530	COG1620	l-lactate permease
GAN21_RS04535	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
GAN21_RS04540	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
GAN21_RS04545	COG0156	8-amino-7-oxononanoate synthase activity
GAN21_RS04590	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
GAN21_RS04605	COG0076	glutamate decarboxylase activity
GAN21_RS04620	COG2318	DinB family
GAN21_RS04625	COG0753	catalase activity
GAN21_RS04635	COG0783	Belongs to the Dps family
GAN21_RS04645	COG0436	Aminotransferase
GAN21_RS04670	COG1136	(ABC) transporter
GAN21_RS04680	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GAN21_RS04690	COG1755	Isoprenylcysteine carboxyl methyltransferase
GAN21_RS04715	COG0579	oxidoreductase
GAN21_RS04735	COG1073	alpha beta
GAN21_RS04755	COG0438	transferase activity, transferring glycosyl groups
GAN21_RS04760	COG0183	Belongs to the thiolase family
GAN21_RS04775	COG0318	PFAM AMP-dependent synthetase and ligase
GAN21_RS04785	COG2814	Major facilitator Superfamily
GAN21_RS04795	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GAN21_RS04805	COG1116	anion transmembrane transporter activity
GAN21_RS04825	COG1609	Transcriptional regulator
GAN21_RS04830	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GAN21_RS04860	COG3711	transcriptional antiterminator
GAN21_RS04865	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GAN21_RS04875	COG3037	sugar-specific permease SgaT UlaA
GAN21_RS04885	COG1328	CTP reductase activity
GAN21_RS04905	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GAN21_RS04910	COG1942	4-Oxalocrotonate Tautomerase
GAN21_RS04920	COG0803	Belongs to the bacterial solute-binding protein 9 family
GAN21_RS04920	COG3443	Belongs to the bacterial solute-binding protein 9 family
GAN21_RS04945	COG2207	Transcriptional regulator
GAN21_RS04945	COG4753	response regulator
GAN21_RS04950	COG2972	Histidine kinase
GAN21_RS04960	COG1210	Utp--glucose-1-phosphate uridylyltransferase
GAN21_RS04965	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
GAN21_RS04970	COG0477	Major facilitator Superfamily
GAN21_RS04975	COG2211	Major facilitator Superfamily
GAN21_RS04980	COG3250	beta-galactosidase activity
GAN21_RS04985	COG1957	nucleoside hydrolase
GAN21_RS05000	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
GAN21_RS05005	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
GAN21_RS05010	COG2807	transmembrane transport
GAN21_RS05015	COG1396	sequence-specific DNA binding
GAN21_RS05030	COG1785	Belongs to the alkaline phosphatase family
GAN21_RS05035	COG0494	nUDIX hydrolase
GAN21_RS05055	COG1510	regulation of RNA biosynthetic process
GAN21_RS05060	COG1012	belongs to the aldehyde dehydrogenase family
GAN21_RS05065	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
GAN21_RS05070	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
GAN21_RS05080	COG0156	8-amino-7-oxononanoate synthase activity
GAN21_RS05095	COG0107	imidazoleglycerol-phosphate synthase activity
GAN21_RS05100	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
GAN21_RS05115	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
GAN21_RS05120	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
GAN21_RS05125	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
GAN21_RS05130	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
GAN21_RS05165	COG2376	Dihydroxyacetone kinase
GAN21_RS05170	COG1461	Dihydroxyacetone kinase
GAN21_RS05175	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
GAN21_RS05180	COG2824	Alkylphosphonate utilization operon protein PhnA
GAN21_RS05185	COG1012	belongs to the aldehyde dehydrogenase family
GAN21_RS05200	COG0596	Alpha beta hydrolase
GAN21_RS05205	COG0789	Transcriptional regulator
GAN21_RS05210	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GAN21_RS05210	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GAN21_RS05210	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GAN21_RS05220	COG1705	Flagellar rod assembly protein muramidase FlgJ
GAN21_RS05220	COG3942	CHAP domain
GAN21_RS05230	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
GAN21_RS05245	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
GAN21_RS05250	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
GAN21_RS05255	COG0747	negative chemotaxis
GAN21_RS05280	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
GAN21_RS05280	COG0463	Glycosyl transferase, family 2
GAN21_RS05285	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GAN21_RS05290	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
GAN21_RS05295	COG3344	reverse transcriptase
GAN21_RS05310	COG3181	Tripartite tricarboxylate transporter family receptor
GAN21_RS05315	COG0778	Nitroreductase
GAN21_RS05320	COG3001	Fructosamine kinase
GAN21_RS05345	COG1136	(ABC) transporter
GAN21_RS05350	COG0577	efflux transmembrane transporter activity
GAN21_RS05370	COG4413	Urea transporter
GAN21_RS05380	COG0832	Belongs to the urease beta subunit family
GAN21_RS05385	COG0804	urea catabolic process
GAN21_RS05390	COG0717	Belongs to the dCTP deaminase family
GAN21_RS05395	COG0523	cobalamin synthesis protein
GAN21_RS05405	COG1141	Ferredoxin
GAN21_RS05435	COG0583	DNA-binding transcription factor activity
GAN21_RS05445	COG1346	cytolysis
GAN21_RS05460	COG1846	Transcriptional regulator
GAN21_RS05465	COG0778	Nitroreductase
GAN21_RS05470	COG2357	RelA SpoT domain protein
GAN21_RS05510	COG1028	Short-chain dehydrogenase reductase Sdr
GAN21_RS05525	COG3835	regulator
GAN21_RS05530	COG2855	membrane
GAN21_RS05535	COG3961	Belongs to the TPP enzyme family
GAN21_RS05540	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
GAN21_RS05545	COG0512	Glutamine amidotransferase of anthranilate synthase
GAN21_RS05555	COG0134	indole-3-glycerol-phosphate synthase activity
GAN21_RS05565	COG0133	tryptophan synthase activity
GAN21_RS05570	COG0159	tryptophan synthase activity
GAN21_RS05590	COG0277	FAD linked oxidase domain protein
GAN21_RS05595	COG0247	lactate metabolic process
GAN21_RS05600	COG1132	(ABC) transporter
GAN21_RS05605	COG1132	(ABC) transporter
GAN21_RS05675	COG0791	NLP P60 protein
GAN21_RS05675	COG0741	lytic transglycosylase activity
GAN21_RS05705	COG2946	Replication initiation factor
GAN21_RS05715	COG1674	ftsk spoiiie
GAN21_RS05740	COG0346	lactoylglutathione lyase activity
GAN21_RS05750	COG1115	amino acid carrier protein
GAN21_RS05755	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
GAN21_RS05760	COG2814	Major facilitator Superfamily
GAN21_RS05765	COG2271	Major facilitator Superfamily
GAN21_RS05770	COG3764	Sortase (surface protein transpeptidase)
GAN21_RS05775	COG1929	Belongs to the glycerate kinase type-1 family
GAN21_RS05785	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
GAN21_RS05805	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
GAN21_RS05810	COG0702	epimerase
GAN21_RS05825	COG1760	l-serine dehydratase
GAN21_RS05830	COG1760	l-serine dehydratase
GAN21_RS05880	COG0471	metal ion transport
GAN21_RS05885	COG2116	formate transmembrane transporter activity
GAN21_RS05890	COG0454	-acetyltransferase
GAN21_RS05900	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
GAN21_RS05900	COG1648	precorrin-2 dehydrogenase activity
GAN21_RS05905	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GAN21_RS05910	COG2146	nitrite reductase [NAD(P)H] activity
GAN21_RS05915	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
GAN21_RS05915	COG1648	precorrin-2 dehydrogenase activity
GAN21_RS05920	COG0737	Belongs to the 5'-nucleotidase family
GAN21_RS05930	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
GAN21_RS05935	COG1140	nitrate reductase beta subunit
GAN21_RS05945	COG2181	nitrate reductase activity
GAN21_RS05955	COG4585	Histidine kinase
GAN21_RS05960	COG2197	response regulator
GAN21_RS05970	COG2223	nitrite transmembrane transporter activity
GAN21_RS05975	COG3344	reverse transcriptase
GAN21_RS05980	COG4187	Peptidase family M20/M25/M40
GAN21_RS05990	COG0039	L-malate dehydrogenase activity
GAN21_RS05995	COG1363	Peptidase, m42
GAN21_RS06000	COG0697	spore germination
GAN21_RS06010	COG2807	transmembrane transport
GAN21_RS06020	COG1263	PTS System
GAN21_RS06020	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GAN21_RS06035	COG1283	sodium-dependent phosphate transmembrane transporter activity
GAN21_RS06055	COG0492	ferredoxin-NADP+ reductase activity
GAN21_RS06060	COG2814	Major facilitator Superfamily
GAN21_RS06065	COG0604	alcohol dehydrogenase
GAN21_RS06095	COG1620	l-lactate permease
GAN21_RS06100	COG0438	transferase activity, transferring glycosyl groups
GAN21_RS06105	COG0579	oxidoreductase
GAN21_RS06120	COG0577	efflux transmembrane transporter activity
GAN21_RS06150	COG3344	reverse transcriptase
GAN21_RS06160	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
GAN21_RS06170	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GAN21_RS06190	COG1304	FMN binding
GAN21_RS06195	COG0523	cobalamin synthesis protein
GAN21_RS06220	COG0786	glutamate:sodium symporter activity
GAN21_RS06225	COG2207	Transcriptional regulator
GAN21_RS06230	COG3250	beta-galactosidase activity
GAN21_RS06250	COG1757	Na H antiporter
GAN21_RS06255	COG2094	Belongs to the DNA glycosylase MPG family
GAN21_RS06260	COG3152	Membrane
GAN21_RS06265	COG4152	abc transporter atp-binding protein
GAN21_RS06270	COG1668	transmembrane transport
GAN21_RS06275	COG1742	UPF0060 membrane protein
GAN21_RS06280	COG2017	converts alpha-aldose to the beta-anomer
GAN21_RS06285	COG2258	MOSC domain
GAN21_RS06290	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
GAN21_RS06300	COG1266	CAAX protease self-immunity
GAN21_RS06305	COG0583	DNA-binding transcription factor activity
GAN21_RS06310	COG3314	Sporulation integral membrane protein YlbJ
GAN21_RS06315	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
GAN21_RS06320	COG1228	amidohydrolase
GAN21_RS06325	COG0659	secondary active sulfate transmembrane transporter activity
GAN21_RS06330	COG1473	amidohydrolase
GAN21_RS06350	COG0385	Bile acid
GAN21_RS06360	COG0346	lactoylglutathione lyase activity
GAN21_RS06365	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GAN21_RS06390	COG1113	amino acid transport
GAN21_RS06415	COG1316	TRANSCRIPTIONal
GAN21_RS06430	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
GAN21_RS06435	COG3383	formate dehydrogenase (NAD+) activity
GAN21_RS06460	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GAN21_RS06465	COG2076	Multidrug Resistance protein
GAN21_RS06470	COG2076	Multidrug Resistance protein
GAN21_RS06475	COG3942	CHAP domain
GAN21_RS06485	COG1757	Na H antiporter
GAN21_RS06495	COG3942	CHAP domain
GAN21_RS06515	COG1960	acyl-CoA dehydrogenase activity
GAN21_RS06545	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
GAN21_RS06580	COG3646	Phage regulatory protein
GAN21_RS06580	COG3645	SOS response
GAN21_RS06590	COG3422	double-strand break repair
GAN21_RS06650	COG1484	DNA-dependent DNA replication
GAN21_RS06705	COG0756	dUTP diphosphatase activity
GAN21_RS06725	COG5484	DNA packaging
GAN21_RS06725	COG3728	DNA packaging
GAN21_RS06730	COG1783	phage Terminase large subunit
GAN21_RS06845	COG1388	LysM domain
GAN21_RS06845	COG5632	N-Acetylmuramoyl-L-alanine amidase
GAN21_RS06850	COG2832	Protein of unknown function (DUF454)
GAN21_RS06855	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GAN21_RS06860	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GAN21_RS06870	COG2186	Transcriptional regulator
GAN21_RS06880	COG1268	BioY protein
GAN21_RS06895	COG1609	Transcriptional regulator
GAN21_RS06900	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
GAN21_RS06905	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
GAN21_RS06910	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
GAN21_RS06920	COG4149	molybdate abc transporter
GAN21_RS06925	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
GAN21_RS06930	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
GAN21_RS06935	COG0521	Mo-molybdopterin cofactor biosynthetic process
GAN21_RS06955	COG0314	molybdopterin synthase activity
GAN21_RS06965	COG0746	molybdenum cofactor guanylyltransferase activity
GAN21_RS06970	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
GAN21_RS06995	COG2348	transferase activity, transferring amino-acyl groups
GAN21_RS07000	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GAN21_RS07005	COG0436	Aminotransferase
GAN21_RS07030	COG2252	PERMEase
GAN21_RS07050	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
GAN21_RS07055	COG0088	Forms part of the polypeptide exit tunnel
GAN21_RS07060	COG0089	rRNA binding
GAN21_RS07065	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
GAN21_RS07070	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
GAN21_RS07075	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
GAN21_RS07080	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
GAN21_RS07085	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
GAN21_RS07090	COG0255	Belongs to the universal ribosomal protein uL29 family
GAN21_RS07100	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
GAN21_RS07115	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
GAN21_RS07120	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
GAN21_RS07125	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
GAN21_RS07135	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
GAN21_RS07140	COG1841	ribosomal large subunit assembly
GAN21_RS07150	COG0201	protein transport
GAN21_RS07165	COG0257	Belongs to the bacterial ribosomal protein bL36 family
GAN21_RS07175	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
GAN21_RS07180	COG0202	RNA polymerase activity
GAN21_RS07185	COG0203	ribosomal protein L17
GAN21_RS07190	COG1122	ATPase activity
GAN21_RS07195	COG1122	ATPase activity
GAN21_RS07205	COG0101	tRNA pseudouridine synthase activity
GAN21_RS07210	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
GAN21_RS07235	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GAN21_RS07275	COG1349	DNA-binding transcription factor activity
GAN21_RS07290	COG3684	Belongs to the aldolase LacD family
GAN21_RS07300	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GAN21_RS07300	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GAN21_RS07310	COG0488	(ABC) transporter
GAN21_RS07315	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GAN21_RS07325	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
GAN21_RS07340	COG1302	Protein conserved in bacteria
GAN21_RS07345	COG2814	Major facilitator Superfamily
GAN21_RS07350	COG4264	IucA IucC family
GAN21_RS07355	COG2814	Major facilitator Superfamily
GAN21_RS07360	COG4264	IucA IucC family
GAN21_RS07365	COG3457	Alanine racemase
GAN21_RS07370	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
GAN21_RS07375	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GAN21_RS07380	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GAN21_RS07385	COG3314	Sporulation integral membrane protein YlbJ
GAN21_RS07395	COG1988	membrane-bound metal-dependent
GAN21_RS07400	COG4284	Utp--glucose-1-phosphate uridylyltransferase
GAN21_RS07405	COG1272	protein, Hemolysin III
GAN21_RS07425	COG2814	Major facilitator Superfamily
GAN21_RS07430	COG0489	protein tyrosine kinase activity
GAN21_RS07495	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GAN21_RS07510	COG3711	transcriptional antiterminator
GAN21_RS07555	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
GAN21_RS07560	COG0210	DNA helicase
GAN21_RS07580	COG2189	Belongs to the N(4) N(6)-methyltransferase family
GAN21_RS07585	COG3421	Type III restriction
GAN21_RS07600	COG1119	ATPase activity
GAN21_RS07605	COG0561	phosphatase activity
GAN21_RS07615	COG2186	Transcriptional regulator
GAN21_RS07620	COG1482	cell wall glycoprotein biosynthetic process
GAN21_RS07635	COG1757	Na H antiporter
GAN21_RS07645	COG0813	purine-nucleoside phosphorylase activity
GAN21_RS07680	COG5146	pantothenate kinase activity
GAN21_RS07695	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GAN21_RS07705	COG0504	CTP synthase activity
GAN21_RS07710	COG2271	Major facilitator Superfamily
GAN21_RS07715	COG4821	SIS domain
GAN21_RS07720	COG0191	fructose-bisphosphate aldolase activity
GAN21_RS07725	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GAN21_RS07730	COG1733	regulation of RNA biosynthetic process
GAN21_RS07745	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
GAN21_RS07750	COG0254	rRNA binding
GAN21_RS07760	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
GAN21_RS07765	COG2890	protein-(glutamine-N5) methyltransferase activity
GAN21_RS07770	COG0009	L-threonylcarbamoyladenylate synthase
GAN21_RS07775	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GAN21_RS07780	COG4475	Protein of unknown function (DUF436)
GAN21_RS07785	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
GAN21_RS07790	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
GAN21_RS07795	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
GAN21_RS07805	COG0356	it plays a direct role in the translocation of protons across the membrane
GAN21_RS07810	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GAN21_RS07820	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GAN21_RS07830	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
GAN21_RS07860	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
GAN21_RS07875	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
GAN21_RS07885	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
GAN21_RS07890	COG0352	thiamine-phosphate diphosphorylase activity
GAN21_RS07895	COG0706	membrane insertase activity
GAN21_RS07900	COG1418	mRNA catabolic process
GAN21_RS07905	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GAN21_RS07910	COG1937	Protein conserved in bacteria
GAN21_RS07925	COG2217	Heavy metal translocating P-type atpase
GAN21_RS07935	COG0772	Belongs to the SEDS family
GAN21_RS07940	COG1181	Belongs to the D-alanine--D-alanine ligase family
GAN21_RS07945	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
GAN21_RS07950	COG0513	Belongs to the DEAD box helicase family
GAN21_RS07965	COG3402	PFAM membrane-flanked domain
GAN21_RS07970	COG0736	holo-[acyl-carrier-protein] synthase activity
GAN21_RS07975	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GAN21_RS07985	COG2337	Toxic component of a toxin-antitoxin (TA) module
GAN21_RS07990	COG2208	phosphoserine phosphatase activity
GAN21_RS07995	COG1366	Belongs to the anti-sigma-factor antagonist family
GAN21_RS08005	COG1191	sigma factor activity
GAN21_RS08010	COG2183	response to ionizing radiation
GAN21_RS08015	COG3091	SprT-like family
GAN21_RS08060	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
GAN21_RS08070	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GAN21_RS08075	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
GAN21_RS08085	COG0028	Belongs to the TPP enzyme family
GAN21_RS08090	COG0129	dihydroxy-acid dehydratase activity
GAN21_RS08095	COG0802	atpase or kinase
GAN21_RS08100	COG1214	PFAM Peptidase M22, glycoprotease
GAN21_RS08105	COG0456	acetyltransferase
GAN21_RS08110	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
GAN21_RS08120	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
GAN21_RS08125	COG0488	(ABC) transporter
GAN21_RS08130	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
GAN21_RS08135	COG2814	Major facilitator Superfamily
GAN21_RS08140	COG1846	Transcriptional regulator
GAN21_RS08150	COG2124	cytochrome p450
GAN21_RS08160	COG1609	Transcriptional regulator
GAN21_RS08165	COG1621	beta-fructofuranosidase activity
GAN21_RS08170	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GAN21_RS08190	COG4512	PFAM Accessory gene regulator B
GAN21_RS08230	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GAN21_RS08235	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GAN21_RS08250	COG1131	(ABC) transporter
GAN21_RS08265	COG1070	Carbohydrate kinase
GAN21_RS08270	COG2610	gluconate transmembrane transporter activity
GAN21_RS08300	COG2706	6-phosphogluconolactonase activity
GAN21_RS08305	COG1012	belongs to the aldehyde dehydrogenase family
GAN21_RS08315	COG1227	inorganic diphosphatase activity
GAN21_RS08320	COG1335	isochorismatase
GAN21_RS08330	COG0077	Prephenate dehydratase
GAN21_RS08330	COG1605	Chorismate mutase
GAN21_RS08340	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
GAN21_RS08350	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
GAN21_RS08360	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
GAN21_RS08365	COG4496	protein, YerC YecD
GAN21_RS08370	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
GAN21_RS08375	COG0210	DNA helicase
GAN21_RS08380	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
GAN21_RS08385	COG4851	CamS sex pheromone cAM373 precursor
GAN21_RS08390	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GAN21_RS08395	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GAN21_RS08405	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GAN21_RS08410	COG1597	lipid kinase activity
GAN21_RS08435	COG0488	(ABC) transporter
GAN21_RS08445	COG1396	sequence-specific DNA binding
GAN21_RS08455	COG2211	Major facilitator Superfamily
GAN21_RS08465	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GAN21_RS08475	COG1528	Iron-storage protein
GAN21_RS08490	COG4129	membrane
GAN21_RS08495	COG0024	Methionine aminopeptidase
GAN21_RS08520	COG0288	reversible hydration of carbon dioxide
GAN21_RS08525	COG1295	ribonuclease BN
GAN21_RS08540	COG4840	Belongs to the UPF0435 family
GAN21_RS08545	COG2309	aminopeptidase activity
GAN21_RS08550	COG1607	acyl-coa hydrolase
GAN21_RS08555	COG0535	radical SAM domain protein
GAN21_RS08560	COG0693	protein deglycase activity
GAN21_RS08565	COG0028	Belongs to the TPP enzyme family
GAN21_RS08570	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GAN21_RS08575	COG2137	regulation of response to DNA damage stimulus
GAN21_RS08585	COG1388	LysM domain
GAN21_RS08585	COG1134	teichoic acid transport
GAN21_RS08595	COG1988	membrane-bound metal-dependent
GAN21_RS08600	COG1194	a g-specific adenine glycosylase
GAN21_RS08605	COG3557	Belongs to the UPF0374 family
GAN21_RS08615	COG0069	glutamate synthase activity
GAN21_RS08620	COG4129	membrane
GAN21_RS08625	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
GAN21_RS08630	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
GAN21_RS08640	COG0735	belongs to the Fur family
GAN21_RS08805	COG0765	amino acid transport
GAN21_RS08810	COG1126	abc transporter atp-binding protein
GAN21_RS08815	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
GAN21_RS08825	COG0363	glucosamine-6-phosphate deaminase activity
GAN21_RS08835	COG0114	fumarate hydratase activity
GAN21_RS08840	COG0248	Ppx GppA phosphatase
GAN21_RS08845	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
GAN21_RS08850	COG0564	pseudouridine synthase activity
GAN21_RS08855	COG4585	Histidine kinase
GAN21_RS08855	COG2203	Gaf domain
GAN21_RS08860	COG2197	response regulator
GAN21_RS08870	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
GAN21_RS08885	COG4399	Belongs to the UPF0754 family
GAN21_RS08890	COG3679	Belongs to the UPF0342 family
GAN21_RS08895	COG0420	3'-5' exonuclease activity
GAN21_RS08905	COG3481	metal-dependent phosphohydrolase, HD sub domain
GAN21_RS08910	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GAN21_RS08925	COG1846	Transcriptional regulator
GAN21_RS08935	COG0537	adenosine 5'-monophosphoramidase activity
GAN21_RS08940	COG1131	(ABC) transporter
GAN21_RS08945	COG4473	ABC transporter
GAN21_RS08950	COG3344	reverse transcriptase
GAN21_RS08960	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
GAN21_RS08970	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
GAN21_RS08975	COG3545	Serine hydrolase
GAN21_RS09065	COG3037	sugar-specific permease SgaT UlaA
GAN21_RS09085	COG3623	hexulose-6-phosphate isomerase
GAN21_RS09090	COG0235	Class ii aldolase
GAN21_RS09110	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
GAN21_RS09115	COG0494	nUDIX hydrolase
GAN21_RS09120	COG1506	peptidase
GAN21_RS09125	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
GAN21_RS09130	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
GAN21_RS09140	COG0656	L-ascorbic acid biosynthetic process
GAN21_RS09145	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GAN21_RS09150	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GAN21_RS09160	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
GAN21_RS09185	COG4193	domain, Protein
GAN21_RS09185	COG5632	N-Acetylmuramoyl-L-alanine amidase
GAN21_RS09185	COG3266	domain, Protein
GAN21_RS09195	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GAN21_RS09195	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GAN21_RS09200	COG0307	riboflavin synthase, alpha
GAN21_RS09205	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GAN21_RS09205	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GAN21_RS09210	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
GAN21_RS09225	COG2267	carboxylic ester hydrolase activity
GAN21_RS09230	COG0039	L-malate dehydrogenase activity
GAN21_RS09240	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
GAN21_RS09245	COG1242	4 iron, 4 sulfur cluster binding
GAN21_RS09250	COG2814	Major facilitator Superfamily
GAN21_RS09255	COG0495	leucyl-tRNA aminoacylation
GAN21_RS09260	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GAN21_RS09265	COG2081	HI0933 family
GAN21_RS09270	COG2244	polysaccharide biosynthetic process
GAN21_RS09275	COG1187	pseudouridine synthase activity
GAN21_RS09285	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GAN21_RS09290	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GAN21_RS09295	COG0510	thiamine kinase activity
GAN21_RS09300	COG0220	tRNA (guanine-N7-)-methyltransferase activity
GAN21_RS09305	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GAN21_RS09315	COG1363	Peptidase, m42
GAN21_RS09320	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GAN21_RS09325	COG4848	Belongs to the UPF0354 family
GAN21_RS09330	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GAN21_RS09335	COG1674	ftsk spoiiie
GAN21_RS09340	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
GAN21_RS09345	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
GAN21_RS09355	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
GAN21_RS09355	COG1605	Chorismate mutase
GAN21_RS09360	COG1609	Transcriptional regulator
GAN21_RS09370	COG0454	-acetyltransferase
GAN21_RS09375	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GAN21_RS09380	COG2759	Belongs to the formate--tetrahydrofolate ligase family
GAN21_RS09385	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
GAN21_RS09395	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GAN21_RS09400	COG0204	Acyl-transferase
GAN21_RS09410	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GAN21_RS09415	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
GAN21_RS09420	COG1764	response to oxidative stress
GAN21_RS09460	COG0456	acetyltransferase
GAN21_RS09495	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
GAN21_RS09500	COG1956	GAF domain-containing protein
GAN21_RS09505	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
GAN21_RS09510	COG1104	cysteine desulfurase activity
GAN21_RS09515	COG0301	tRNA thio-modification
GAN21_RS09525	COG0616	signal peptide processing
GAN21_RS09530	COG1714	RDD family
GAN21_RS09535	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
GAN21_RS09540	COG0827	DNA restriction-modification system
GAN21_RS09545	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
GAN21_RS09550	COG0589	response to stress
GAN21_RS09555	COG0686	Belongs to the AlaDH PNT family
GAN21_RS09565	COG0006	proline dipeptidase activity
GAN21_RS09570	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
GAN21_RS09580	COG4109	DRTGG domain
GAN21_RS09585	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
GAN21_RS09590	COG0587	DNA-directed DNA polymerase activity
GAN21_RS09595	COG0281	malic enzyme
GAN21_RS09600	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
GAN21_RS09605	COG0825	malonyl-CoA metabolic process
GAN21_RS09610	COG0205	6-phosphofructokinase activity
GAN21_RS09615	COG0469	pyruvate kinase activity
GAN21_RS09620	COG0372	Belongs to the citrate synthase family
GAN21_RS09625	COG0538	isocitrate dehydrogenase activity
GAN21_RS09630	COG0745	RESPONSE REGULATOR receiver
GAN21_RS09635	COG5002	protein histidine kinase activity
GAN21_RS09640	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GAN21_RS09640	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GAN21_RS09650	COG0237	dephospho-CoA kinase activity
GAN21_RS09665	COG3611	Membrane attachment protein
GAN21_RS09670	COG1484	DNA-dependent DNA replication
GAN21_RS09680	COG0833	amino acid
GAN21_RS09685	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
GAN21_RS09690	COG0291	Belongs to the bacterial ribosomal protein bL35 family
GAN21_RS09695	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
GAN21_RS09710	COG0544	peptidyl-prolyl cis-trans isomerase activity
GAN21_RS09720	COG0218	Necessary for normal cell division and for the maintenance of normal septation
GAN21_RS09725	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
GAN21_RS09735	COG0181	hydroxymethylbilane synthase activity
GAN21_RS09750	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
GAN21_RS09760	COG2818	Glycosylase
GAN21_RS09765	COG0525	valine-tRNA ligase activity
GAN21_RS09770	COG0285	dihydrofolate synthase activity
GAN21_RS09780	COG2003	Belongs to the UPF0758 family
GAN21_RS09805	COG2868	ribosomal protein
GAN21_RS09815	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
GAN21_RS09825	COG0632	four-way junction helicase activity
GAN21_RS09830	COG2255	four-way junction helicase activity
GAN21_RS09835	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
GAN21_RS09845	COG1862	Preprotein translocase
GAN21_RS09850	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GAN21_RS09850	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GAN21_RS09855	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
GAN21_RS09855	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
GAN21_RS09860	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GAN21_RS09870	COG1490	D-aminoacyl-tRNA deacylase activity
GAN21_RS09875	COG0860	N-Acetylmuramoyl-L-alanine amidase
GAN21_RS09885	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
GAN21_RS09895	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
GAN21_RS09900	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
GAN21_RS09905	COG1959	2 iron, 2 sulfur cluster binding
GAN21_RS09920	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GAN21_RS09925	COG1104	cysteine desulfurase activity
GAN21_RS09930	COG0482	sulfurtransferase activity
GAN21_RS09940	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
GAN21_RS09945	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
GAN21_RS09950	COG4472	Bacterial protein of unknown function (DUF965)
GAN21_RS09955	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
GAN21_RS09960	COG3906	Belongs to the UPF0473 family
GAN21_RS09965	COG4122	O-methyltransferase activity
GAN21_RS09970	COG0826	peptidase U32
GAN21_RS09975	COG0826	peptidase U32
GAN21_RS09980	COG0572	uridine kinase
GAN21_RS09990	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
GAN21_RS09995	COG1984	allophanate hydrolase subunit 2
GAN21_RS10000	COG0511	ligase activity, forming carbon-carbon bonds
GAN21_RS10005	COG0439	Biotin carboxylase
GAN21_RS10010	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
GAN21_RS10015	COG1914	H( )-stimulated, divalent metal cation uptake system
GAN21_RS10020	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
GAN21_RS10025	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
GAN21_RS10030	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
GAN21_RS10035	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
GAN21_RS10040	COG1534	Rna-binding protein
GAN21_RS10050	COG1713	HD superfamily hydrolase involved in NAD metabolism
GAN21_RS10055	COG0799	negative regulation of ribosome biogenesis
GAN21_RS10060	COG2226	methyltransferase
GAN21_RS10065	COG1596	polysaccharide export
GAN21_RS10065	COG1555	photosystem II stabilization
GAN21_RS10070	COG2131	deaminase
GAN21_RS10075	COG2333	competence protein COMEC
GAN21_RS10075	COG0658	competence protein
GAN21_RS10080	COG1466	dna polymerase III delta subunit
GAN21_RS10085	COG0268	Binds directly to 16S ribosomal RNA
GAN21_RS10095	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GAN21_RS10115	COG0484	heat shock protein binding
GAN21_RS10120	COG2264	protein methyltransferase activity
GAN21_RS10125	COG1385	rRNA (uridine-N3-)-methyltransferase activity
GAN21_RS10130	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GAN21_RS10135	COG3344	reverse transcriptase
GAN21_RS10150	COG1030	water channel activity
GAN21_RS10155	COG4864	UPF0365 protein
GAN21_RS10165	COG1702	phosphate starvation-inducible protein PhoH
GAN21_RS10175	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
GAN21_RS10185	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
GAN21_RS10190	COG1381	Involved in DNA repair and RecF pathway recombination
GAN21_RS10195	COG0423	glycine-tRNA ligase activity
GAN21_RS10200	COG0517	IMP dehydrogenase activity
GAN21_RS10205	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
GAN21_RS10210	COG0358	DNA primase activity
GAN21_RS10215	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GAN21_RS10220	COG2384	SAM-dependent methyltransferase
GAN21_RS10225	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
GAN21_RS10230	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
GAN21_RS10235	COG0513	Belongs to the DEAD box helicase family
GAN21_RS10240	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
GAN21_RS10245	COG1121	(ABC) transporter
GAN21_RS10250	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GAN21_RS10255	COG0735	belongs to the Fur family
GAN21_RS10260	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
GAN21_RS10270	COG0768	penicillin binding
GAN21_RS10275	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
GAN21_RS10280	COG0573	inorganic phosphate transmembrane transporter activity
GAN21_RS10285	COG0581	inorganic phosphate transmembrane transporter activity
GAN21_RS10290	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
GAN21_RS10295	COG0704	Plays a role in the regulation of phosphate uptake
GAN21_RS10305	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
GAN21_RS10310	COG0705	Rhomboid family
GAN21_RS10315	COG4483	Protein conserved in bacteria
GAN21_RS10320	COG1940	carbohydrate kinase activity
GAN21_RS10325	COG0011	TIGRFAM Protein of
GAN21_RS10330	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GAN21_RS10335	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GAN21_RS10365	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
GAN21_RS10370	COG0404	The glycine cleavage system catalyzes the degradation of glycine
GAN21_RS10380	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GAN21_RS10385	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GAN21_RS10390	COG0095	Lipoate-protein ligase
GAN21_RS10405	COG0006	proline dipeptidase activity
GAN21_RS10410	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
GAN21_RS10415	COG0511	ligase activity, forming carbon-carbon bonds
GAN21_RS10420	COG0439	Biotin carboxylase
GAN21_RS10425	COG1302	Protein conserved in bacteria
GAN21_RS10435	COG1570	exodeoxyribonuclease VII activity
GAN21_RS10440	COG1722	exodeoxyribonuclease VII activity
GAN21_RS10445	COG0142	geranyltranstransferase activity
GAN21_RS10450	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
GAN21_RS10455	COG1438	arginine binding
GAN21_RS10460	COG0497	DNA recombination
GAN21_RS10465	COG0280	phosphate acetyltransferase
GAN21_RS10470	COG3426	butyrate kinase activity
GAN21_RS10475	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GAN21_RS10480	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
GAN21_RS10485	COG0022	dehydrogenase e1 component
GAN21_RS10490	COG0508	dehydrogenase complex catalyzes the overall conversion of
GAN21_RS10500	COG4129	membrane
GAN21_RS10510	COG2195	Cleaves the N-terminal amino acid of tripeptides
GAN21_RS10540	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
GAN21_RS10545	COG1234	tRNA 3'-trailer cleavage
GAN21_RS10550	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GAN21_RS10560	COG0667	Aldo Keto reductase
GAN21_RS10565	COG0494	nUDIX hydrolase
GAN21_RS10570	COG0735	belongs to the Fur family
GAN21_RS10585	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
GAN21_RS10590	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
GAN21_RS10595	COG1187	pseudouridine synthase activity
GAN21_RS10600	COG0745	RESPONSE REGULATOR receiver
GAN21_RS10615	COG1141	Ferredoxin
GAN21_RS10625	COG0514	ATP-dependent DNA helicase (RecQ)
GAN21_RS10635	COG0492	ferredoxin-NADP+ reductase activity
GAN21_RS10640	COG0252	asparaginase activity
GAN21_RS10650	COG0539	negative regulation of cytoplasmic translation
GAN21_RS10655	COG1160	GTP binding
GAN21_RS10660	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
GAN21_RS10680	COG0142	geranyltranstransferase activity
GAN21_RS10685	COG0105	UTP biosynthetic process
GAN21_RS10695	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
GAN21_RS10705	COG0457	Tetratricopeptide repeat
GAN21_RS10710	COG5582	Belongs to the UPF0302 family
GAN21_RS10715	COG4347	Protein of unknown function (DUF1405)
GAN21_RS10725	COG1694	Mazg nucleotide pyrophosphohydrolase
GAN21_RS10730	COG0438	transferase activity, transferring glycosyl groups
GAN21_RS10735	COG0617	tRNA 3'-terminal CCA addition
GAN21_RS10750	COG0017	Asparaginyl-tRNA synthetase
GAN21_RS10755	COG3935	DnaD domain protein
GAN21_RS10760	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
GAN21_RS10770	COG4499	WXG100 protein secretion system (Wss), protein YukC
GAN21_RS10770	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GAN21_RS10785	COG4474	Belongs to the UPF0398 family
GAN21_RS10790	COG3599	regulation of cell shape
GAN21_RS10800	COG0116	Belongs to the methyltransferase superfamily
GAN21_RS10805	COG2962	Rard protein
GAN21_RS10810	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
GAN21_RS10815	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GAN21_RS10825	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
GAN21_RS10835	COG1413	lyase activity
GAN21_RS10870	COG2190	(PTS) system
GAN21_RS10880	COG0793	Belongs to the peptidase S41A family
GAN21_RS10890	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
GAN21_RS10895	COG0671	phosphoesterase, PA-phosphatase related
GAN21_RS10905	COG5002	protein histidine kinase activity
GAN21_RS10910	COG0567	Dehydrogenase, E1 component
GAN21_RS10935	COG0714	Associated with various cellular activities
GAN21_RS10940	COG4548	von Willebrand factor, type A
GAN21_RS10945	COG1114	Component of the transport system for branched-chain amino acids
GAN21_RS10950	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
GAN21_RS10960	COG3853	Toxic anion resistance protein (TelA)
GAN21_RS10980	COG1278	Cold shock
GAN21_RS11000	COG1473	amidohydrolase
GAN21_RS11005	COG2171	N-acyltransferase activity
GAN21_RS11010	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
GAN21_RS11015	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GAN21_RS11020	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
GAN21_RS11025	COG0488	(ABC) transporter
GAN21_RS11030	COG2996	Protein conserved in bacteria
GAN21_RS11060	COG1363	Peptidase, m42
GAN21_RS11065	COG0287	Prephenate dehydrogenase
GAN21_RS11070	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GAN21_RS11080	COG1942	4-Oxalocrotonate Tautomerase
GAN21_RS11100	COG0628	permease
GAN21_RS11110	COG3711	transcriptional antiterminator
GAN21_RS11115	COG1115	amino acid carrier protein
GAN21_RS11120	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GAN21_RS11130	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
GAN21_RS11135	COG4841	protein insertion into membrane
GAN21_RS11140	COG0824	Thioesterase
GAN21_RS11150	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
GAN21_RS11155	COG1970	mechanosensitive ion channel activity
GAN21_RS11160	COG0419	ATPase involved in DNA repair
GAN21_RS11165	COG0420	3'-5' exonuclease activity
GAN21_RS11170	COG4846	Membrane protein involved in cytochrome C biogenesis
GAN21_RS11175	COG3763	UPF0154 protein
GAN21_RS11185	COG4224	UPF0291 protein
GAN21_RS11195	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
GAN21_RS11205	COG0516	GMP reductase activity
GAN21_RS11210	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
GAN21_RS11220	COG0833	amino acid
GAN21_RS11235	COG0083	homoserine kinase activity
GAN21_RS11240	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
GAN21_RS11245	COG0460	homoserine dehydrogenase
GAN21_RS11250	COG0527	aspartate kinase activity
GAN21_RS11270	COG1525	nuclease
GAN21_RS11300	COG0584	glycerophosphoryl diester phosphodiesterase
GAN21_RS11325	COG0789	Transcriptional regulator
GAN21_RS11330	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
GAN21_RS11335	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
GAN21_RS11340	COG0386	Belongs to the glutathione peroxidase family
GAN21_RS11345	COG2267	carboxylic ester hydrolase activity
GAN21_RS11350	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
GAN21_RS11355	COG1923	regulation of RNA biosynthetic process
GAN21_RS11360	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
GAN21_RS11370	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
GAN21_RS11375	COG1619	proteins homologs of microcin C7 resistance protein MccF
GAN21_RS11380	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
GAN21_RS11385	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
GAN21_RS11405	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GAN21_RS11415	COG1013	pyruvate-flavodoxin oxidoreductase activity
GAN21_RS11420	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
GAN21_RS11420	COG0674	pyruvate-flavodoxin oxidoreductase activity
GAN21_RS11425	COG1692	metallophosphoesterase
GAN21_RS11445	COG1418	mRNA catabolic process
GAN21_RS11450	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
GAN21_RS11455	COG1058	Belongs to the CinA family
GAN21_RS11455	COG1546	Belongs to the CinA family
GAN21_RS11475	COG0300	oxidoreductase activity
GAN21_RS11480	COG0612	Peptidase, M16
GAN21_RS11485	COG0612	Peptidase, M16
GAN21_RS11490	COG2188	Transcriptional regulator
GAN21_RS11505	COG1185	polyribonucleotide nucleotidyltransferase activity
GAN21_RS11515	COG0196	riboflavin kinase activity
GAN21_RS11520	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
GAN21_RS11525	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
GAN21_RS11535	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
GAN21_RS11540	COG1358	cellular component organization or biogenesis
GAN21_RS11545	COG2740	Nucleic-acid-binding protein implicated in transcription termination
GAN21_RS11550	COG0195	Participates in both transcription termination and antitermination
GAN21_RS11555	COG0779	Required for maturation of 30S ribosomal subunits
GAN21_RS11565	COG0442	prolyl-tRNA aminoacylation
GAN21_RS11575	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
GAN21_RS11580	COG4589	Belongs to the CDS family
GAN21_RS11590	COG0233	cytoplasmic translational termination
GAN21_RS11595	COG0528	UMP kinase activity
GAN21_RS11600	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
GAN21_RS11605	COG0052	Belongs to the universal ribosomal protein uS2 family
GAN21_RS11610	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
GAN21_RS11615	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
GAN21_RS11620	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
GAN21_RS11625	COG4974	Belongs to the 'phage' integrase family
GAN21_RS11630	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
GAN21_RS11635	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GAN21_RS11640	COG0758	DNA mediated transformation
GAN21_RS11650	COG0045	succinate-CoA ligase (ADP-forming) activity
GAN21_RS11660	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GAN21_RS11675	COG4485	Bacterial membrane protein, YfhO
GAN21_RS11715	COG0336	Belongs to the RNA methyltransferase TrmD family
GAN21_RS11720	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
GAN21_RS11725	COG0228	four-way junction DNA binding
GAN21_RS11745	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
GAN21_RS11760	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GAN21_RS11765	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
GAN21_RS11770	COG0552	protein localization to endoplasmic reticulum
GAN21_RS11775	COG1196	nuclear chromosome segregation
GAN21_RS11780	COG0571	ribonuclease III activity
GAN21_RS11785	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GAN21_RS11800	COG0416	fatty acid biosynthetic process
GAN21_RS11805	COG1349	DNA-binding transcription factor activity
GAN21_RS11815	COG1760	l-serine dehydratase
GAN21_RS11820	COG1760	l-serine dehydratase
GAN21_RS11830	COG1302	Protein conserved in bacteria
GAN21_RS11845	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
GAN21_RS11850	COG1162	GTPase activity
GAN21_RS11855	COG2124	cytochrome p450
GAN21_RS11870	COG0820	rRNA (adenine-C2-)-methyltransferase activity
GAN21_RS11875	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GAN21_RS11875	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GAN21_RS11880	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
GAN21_RS11885	COG0242	peptide deformylase activity
GAN21_RS11890	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
GAN21_RS11895	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
GAN21_RS11900	COG1758	RNA polymerase activity
GAN21_RS11920	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
GAN21_RS11925	COG0284	orotidine-5'-phosphate decarboxylase activity
GAN21_RS11930	COG0167	dihydroorotate dehydrogenase activity
GAN21_RS11940	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
GAN21_RS11945	COG0505	Belongs to the CarA family
GAN21_RS11965	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
GAN21_RS11970	COG0564	pseudouridine synthase activity
GAN21_RS11975	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
GAN21_RS11980	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
GAN21_RS11985	COG3599	regulation of cell shape
GAN21_RS11995	COG0673	inositol 2-dehydrogenase activity
GAN21_RS12000	COG4409	exo-alpha-(2->6)-sialidase activity
GAN21_RS12010	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GAN21_RS12015	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GAN21_RS12025	COG4975	Glucose uptake
GAN21_RS12030	COG1869	D-ribose catabolic process
GAN21_RS12035	COG0762	integral membrane protein
GAN21_RS12040	COG1799	cell septum assembly
GAN21_RS12045	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
GAN21_RS12055	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
GAN21_RS12060	COG0849	cell division
GAN21_RS12070	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
GAN21_RS12080	COG0768	penicillin binding
GAN21_RS12085	COG4839	cell division protein FtsL
GAN21_RS12090	COG0275	rRNA processing
GAN21_RS12095	COG2001	Belongs to the MraZ family
GAN21_RS12100	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
GAN21_RS12105	COG0454	-acetyltransferase
GAN21_RS12110	COG1011	Hydrolase
GAN21_RS12125	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GAN21_RS12185	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
GAN21_RS12190	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
GAN21_RS12195	COG1053	succinate dehydrogenase
GAN21_RS12200	COG2009	succinate dehydrogenase
GAN21_RS12205	COG0322	excinuclease ABC activity
GAN21_RS12210	COG3118	belongs to the thioredoxin family
GAN21_RS12215	COG1193	negative regulation of DNA recombination
GAN21_RS12220	COG1796	DNA polymerase
GAN21_RS12220	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
GAN21_RS12235	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GAN21_RS12250	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
GAN21_RS12255	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GAN21_RS12260	COG0333	Belongs to the bacterial ribosomal protein bL32 family
GAN21_RS12280	COG0742	ribosomal rna small subunit methyltransferase
GAN21_RS12290	COG4471	UPF0298 protein
GAN21_RS12295	COG0584	glycerophosphoryl diester phosphodiesterase
GAN21_RS12300	COG3679	Belongs to the UPF0342 family
GAN21_RS12315	COG0109	protoheme IX farnesyltransferase activity
GAN21_RS12335	COG3344	reverse transcriptase
GAN21_RS12340	COG3344	reverse transcriptase
GAN21_RS12345	COG0772	Belongs to the SEDS family
GAN21_RS12350	COG4838	Belongs to the UPF0358 family
GAN21_RS12355	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
GAN21_RS12360	COG4896	Protein conserved in bacteria
GAN21_RS12365	COG1902	pentaerythritol trinitrate reductase activity
GAN21_RS12370	COG1217	gtp-binding protein TYPA
GAN21_RS12380	COG0483	inositol monophosphate 1-phosphatase activity
GAN21_RS12385	COG4493	Belongs to the UPF0637 family
GAN21_RS12400	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
GAN21_RS12405	COG1177	transmembrane transport
GAN21_RS12415	COG3842	ATPase activity
GAN21_RS12425	COG4476	Belongs to the UPF0223 family