locus-tag	class	description
DRC71_RS00010	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
DRC71_RS00015	COG2827	Endonuclease containing a URI domain
DRC71_RS00020	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
DRC71_RS00025	COG4467	Involved in initiation control of chromosome replication
DRC71_RS00030	COG1774	PSP1 C-terminal conserved region
DRC71_RS00035	COG0470	DNA polymerase III
DRC71_RS00040	COG3870	Protein conserved in bacteria
DRC71_RS00045	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
DRC71_RS00050	COG1982	Orn Lys Arg decarboxylase major
DRC71_RS00075	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
DRC71_RS00080	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
DRC71_RS00085	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
DRC71_RS00090	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
DRC71_RS00100	COG2188	Transcriptional regulator
DRC71_RS00105	COG0366	Alpha amylase catalytic
DRC71_RS00110	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DRC71_RS00110	COG1263	PTS System
DRC71_RS00120	COG0493	'glutamate synthase
DRC71_RS00125	COG0067	glutamate synthase
DRC71_RS00125	COG0069	glutamate synthase activity
DRC71_RS00125	COG0070	glutamate synthase
DRC71_RS00130	COG0583	DNA-binding transcription factor activity
DRC71_RS00145	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
DRC71_RS00160	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DRC71_RS00180	COG1131	(ABC) transporter
DRC71_RS00230	COG0626	cystathionine gamma-synthase activity
DRC71_RS00235	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
DRC71_RS00240	COG2272	Belongs to the type-B carboxylesterase lipase family
DRC71_RS00245	COG0733	neurotransmitter:sodium symporter activity
DRC71_RS00255	COG0745	RESPONSE REGULATOR receiver
DRC71_RS00260	COG2205	protein histidine kinase activity
DRC71_RS00270	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
DRC71_RS00275	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
DRC71_RS00290	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
DRC71_RS00295	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DRC71_RS00295	COG0574	Belongs to the PEP-utilizing enzyme family
DRC71_RS00325	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
DRC71_RS00335	COG1486	melibiose metabolic process
DRC71_RS00340	COG1263	PTS System
DRC71_RS00340	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DRC71_RS00360	COG2210	Belongs to the sulfur carrier protein TusA family
DRC71_RS00365	COG1937	Protein conserved in bacteria
DRC71_RS00370	COG0730	response to heat
DRC71_RS00375	COG2814	Major facilitator Superfamily
DRC71_RS00395	COG3682	Transcriptional regulator
DRC71_RS00420	COG1124	(ABC) transporter
DRC71_RS00425	COG0444	Belongs to the ABC transporter superfamily
DRC71_RS00430	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DRC71_RS00435	COG0601	transmembrane transport
DRC71_RS00440	COG0747	negative chemotaxis
DRC71_RS00465	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
DRC71_RS00485	COG1525	nuclease
DRC71_RS00505	COG0518	GMP synthase (glutamine-hydrolyzing) activity
DRC71_RS00505	COG0519	Catalyzes the synthesis of GMP from XMP
DRC71_RS00510	COG0516	GMP reductase activity
DRC71_RS00510	COG0517	IMP dehydrogenase activity
DRC71_RS00515	COG2233	PERMEase
DRC71_RS00520	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
DRC71_RS00535	COG5183	chlorophyll binding
DRC71_RS00540	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DRC71_RS00545	COG1823	symporter activity
DRC71_RS00570	COG0778	Nitroreductase
DRC71_RS00575	COG0450	alkyl hydroperoxide reductase
DRC71_RS00590	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
DRC71_RS00600	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
DRC71_RS00605	COG2011	ABC-type metal ion transport system permease component
DRC71_RS00610	COG1464	Belongs to the NlpA lipoprotein family
DRC71_RS00615	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
DRC71_RS00630	COG3842	ATPase activity
DRC71_RS00635	COG0673	inositol 2-dehydrogenase activity
DRC71_RS00640	COG0395	ABC-type sugar transport system, permease component
DRC71_RS00645	COG1175	transmembrane transport
DRC71_RS00655	COG4977	sequence-specific DNA binding
DRC71_RS00655	COG1917	Cupin 2, conserved barrel domain protein
DRC71_RS00665	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
DRC71_RS00675	COG0360	Binds together with S18 to 16S ribosomal RNA
DRC71_RS00685	COG1668	transmembrane transport
DRC71_RS00690	COG1131	(ABC) transporter
DRC71_RS00695	COG0012	GTP binding
DRC71_RS00700	COG4481	Protein conserved in bacteria
DRC71_RS00705	COG0668	transmembrane transport
DRC71_RS00710	COG1475	DNA binding
DRC71_RS00715	COG0626	cystathionine gamma-synthase activity
DRC71_RS00720	COG0626	cystathionine gamma-synthase activity
DRC71_RS00725	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
DRC71_RS00725	COG0646	methionine synthase
DRC71_RS00735	COG0829	nickel cation binding
DRC71_RS00745	COG0830	nickel cation binding
DRC71_RS00750	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
DRC71_RS00760	COG2388	GCN5-related N-acetyl-transferase
DRC71_RS00765	COG1846	Transcriptional regulator
DRC71_RS00770	COG0346	lactoylglutathione lyase activity
DRC71_RS00775	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
DRC71_RS00780	COG0400	carboxylic ester hydrolase activity
DRC71_RS00805	COG0357	Ribosomal RNA small subunit methyltransferase G
DRC71_RS00810	COG0445	tRNA wobble uridine modification
DRC71_RS00815	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
DRC71_RS00820	COG0594	ribonuclease P activity
DRC71_RS00830	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
DRC71_RS00835	COG0592	DNA-directed DNA polymerase activity
DRC71_RS00840	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
DRC71_RS00840	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
DRC71_RS00845	COG2501	S4 domain
DRC71_RS00850	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
DRC71_RS00855	COG0187	DNA topoisomerase II activity
DRC71_RS00865	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
DRC71_RS00870	COG2986	histidine ammonia-lyase
DRC71_RS00880	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
DRC71_RS00890	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
DRC71_RS00895	COG4241	membrane
DRC71_RS00900	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
DRC71_RS00905	COG0359	binds to the 23S rRNA
DRC71_RS00910	COG0305	Participates in initiation and elongation during chromosome replication
DRC71_RS00915	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
DRC71_RS00920	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DRC71_RS00940	COG0745	RESPONSE REGULATOR receiver
DRC71_RS00945	COG5002	protein histidine kinase activity
DRC71_RS00950	COG4863	YycH protein
DRC71_RS00960	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
DRC71_RS00980	COG0584	glycerophosphoryl diester phosphodiesterase
DRC71_RS00985	COG2030	dehydratase
DRC71_RS01010	COG1846	Transcriptional regulator
DRC71_RS01010	COG1940	carbohydrate kinase activity
DRC71_RS01020	COG2210	Belongs to the sulfur carrier protein TusA family
DRC71_RS01025	COG1937	Protein conserved in bacteria
DRC71_RS01030	COG0730	response to heat
DRC71_RS01065	COG2003	Belongs to the UPF0758 family
DRC71_RS01145	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
DRC71_RS01180	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
DRC71_RS01225	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
DRC71_RS01245	COG0640	Transcriptional regulator
DRC71_RS01250	COG2217	Heavy metal translocating P-type atpase
DRC71_RS01275	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
DRC71_RS01290	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
DRC71_RS01300	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
DRC71_RS01340	COG0531	amino acid
DRC71_RS01345	COG2217	Heavy metal translocating P-type atpase
DRC71_RS01360	COG3655	Transcriptional regulator
DRC71_RS01375	COG2188	Transcriptional regulator
DRC71_RS01380	COG2723	6-phospho-beta-galactosidase activity
DRC71_RS01390	COG0415	Belongs to the DNA photolyase family
DRC71_RS01405	COG0702	epimerase
DRC71_RS01410	COG2130	NADP-dependent
DRC71_RS01420	COG3655	Transcriptional regulator
DRC71_RS01425	COG3177	Filamentation induced by cAMP protein fic
DRC71_RS01430	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DRC71_RS01435	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DRC71_RS01435	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DRC71_RS01440	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
DRC71_RS01445	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DRC71_RS01465	COG2235	arginine
DRC71_RS01480	COG2197	response regulator
DRC71_RS01485	COG4585	Histidine kinase
DRC71_RS01485	COG2203	Gaf domain
DRC71_RS01490	COG0842	Transport permease protein
DRC71_RS01495	COG1131	(ABC) transporter
DRC71_RS01515	COG0431	NADPH-dependent FMN reductase
DRC71_RS01520	COG4932	domain protein
DRC71_RS01520	COG3583	domain protein
DRC71_RS01520	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
DRC71_RS01540	COG1609	Transcriptional regulator
DRC71_RS01550	COG0673	inositol 2-dehydrogenase activity
DRC71_RS01560	COG0366	Alpha amylase catalytic
DRC71_RS01570	COG3833	ABC-type maltose transport systems, permease component
DRC71_RS01575	COG1175	transmembrane transport
DRC71_RS01585	COG3842	ATPase activity
DRC71_RS01590	COG0475	glutathione-regulated potassium exporter activity
DRC71_RS01595	COG0490	domain, Protein
DRC71_RS01605	COG0346	lactoylglutathione lyase activity
DRC71_RS01635	COG1131	(ABC) transporter
DRC71_RS01645	COG0366	Alpha amylase catalytic
DRC71_RS01650	COG2188	Transcriptional regulator
DRC71_RS01655	COG2222	sugar isomerase
DRC71_RS01660	COG1105	Belongs to the carbohydrate kinase PfkB family
DRC71_RS01675	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
DRC71_RS01675	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DRC71_RS01680	COG3715	PTS system
DRC71_RS01685	COG3716	PTS system mannose fructose sorbose family IID component
DRC71_RS01695	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
DRC71_RS01715	COG3314	Sporulation integral membrane protein YlbJ
DRC71_RS01735	COG1063	alcohol dehydrogenase
DRC71_RS01750	COG1620	l-lactate permease
DRC71_RS01755	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
DRC71_RS01760	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
DRC71_RS01765	COG0156	8-amino-7-oxononanoate synthase activity
DRC71_RS01810	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
DRC71_RS01825	COG0076	glutamate decarboxylase activity
DRC71_RS01840	COG2318	DinB family
DRC71_RS01845	COG0753	catalase activity
DRC71_RS01855	COG0783	Belongs to the Dps family
DRC71_RS01865	COG0436	Aminotransferase
DRC71_RS01890	COG1136	(ABC) transporter
DRC71_RS01900	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DRC71_RS01920	COG1755	Isoprenylcysteine carboxyl methyltransferase
DRC71_RS01945	COG0579	oxidoreductase
DRC71_RS01970	COG1073	alpha beta
DRC71_RS01990	COG0438	transferase activity, transferring glycosyl groups
DRC71_RS01995	COG0183	Belongs to the thiolase family
DRC71_RS02005	COG1960	acyl-CoA dehydrogenase activity
DRC71_RS02010	COG0318	PFAM AMP-dependent synthetase and ligase
DRC71_RS02020	COG2814	Major facilitator Superfamily
DRC71_RS02030	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DRC71_RS02040	COG1116	anion transmembrane transporter activity
DRC71_RS02060	COG1609	Transcriptional regulator
DRC71_RS02065	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DRC71_RS02120	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
DRC71_RS02155	COG3711	transcriptional antiterminator
DRC71_RS02160	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DRC71_RS02170	COG3037	sugar-specific permease SgaT UlaA
DRC71_RS02180	COG1328	CTP reductase activity
DRC71_RS02200	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DRC71_RS02205	COG1942	4-Oxalocrotonate Tautomerase
DRC71_RS02215	COG0803	Belongs to the bacterial solute-binding protein 9 family
DRC71_RS02215	COG3443	Belongs to the bacterial solute-binding protein 9 family
DRC71_RS02240	COG2207	Transcriptional regulator
DRC71_RS02240	COG4753	response regulator
DRC71_RS02245	COG2972	Histidine kinase
DRC71_RS02255	COG1210	Utp--glucose-1-phosphate uridylyltransferase
DRC71_RS02260	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
DRC71_RS02265	COG0477	Major facilitator Superfamily
DRC71_RS02270	COG2211	Major facilitator Superfamily
DRC71_RS02275	COG3250	beta-galactosidase activity
DRC71_RS02280	COG1957	nucleoside hydrolase
DRC71_RS02315	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
DRC71_RS02320	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
DRC71_RS02325	COG2807	transmembrane transport
DRC71_RS02330	COG1396	sequence-specific DNA binding
DRC71_RS02345	COG1785	Belongs to the alkaline phosphatase family
DRC71_RS02370	COG1510	regulation of RNA biosynthetic process
DRC71_RS02375	COG1012	belongs to the aldehyde dehydrogenase family
DRC71_RS02380	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
DRC71_RS02385	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
DRC71_RS02395	COG0156	8-amino-7-oxononanoate synthase activity
DRC71_RS02410	COG0107	imidazoleglycerol-phosphate synthase activity
DRC71_RS02415	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
DRC71_RS02430	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
DRC71_RS02435	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
DRC71_RS02440	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
DRC71_RS02445	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
DRC71_RS02480	COG2376	Dihydroxyacetone kinase
DRC71_RS02485	COG1461	Dihydroxyacetone kinase
DRC71_RS02490	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
DRC71_RS02495	COG2824	Alkylphosphonate utilization operon protein PhnA
DRC71_RS02500	COG1012	belongs to the aldehyde dehydrogenase family
DRC71_RS02515	COG0596	Alpha beta hydrolase
DRC71_RS02520	COG0789	Transcriptional regulator
DRC71_RS02525	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DRC71_RS02525	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DRC71_RS02525	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DRC71_RS02535	COG3942	CHAP domain
DRC71_RS02535	COG1705	Flagellar rod assembly protein muramidase FlgJ
DRC71_RS02545	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
DRC71_RS02550	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
DRC71_RS02555	COG0747	negative chemotaxis
DRC71_RS02580	COG0463	Glycosyl transferase, family 2
DRC71_RS02580	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
DRC71_RS02585	COG0463	Glycosyl transferase, family 2
DRC71_RS02585	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
DRC71_RS02590	COG0438	transferase activity, transferring glycosyl groups
DRC71_RS02595	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DRC71_RS02600	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
DRC71_RS02615	COG3181	Tripartite tricarboxylate transporter family receptor
DRC71_RS02620	COG0778	Nitroreductase
DRC71_RS02625	COG3001	Fructosamine kinase
DRC71_RS02650	COG1136	(ABC) transporter
DRC71_RS02655	COG0577	efflux transmembrane transporter activity
DRC71_RS02675	COG4413	Urea transporter
DRC71_RS02685	COG0832	Belongs to the urease beta subunit family
DRC71_RS02690	COG0804	urea catabolic process
DRC71_RS02695	COG0717	Belongs to the dCTP deaminase family
DRC71_RS02700	COG0523	cobalamin synthesis protein
DRC71_RS02710	COG1141	Ferredoxin
DRC71_RS02735	COG0583	DNA-binding transcription factor activity
DRC71_RS02745	COG1346	cytolysis
DRC71_RS02760	COG1846	Transcriptional regulator
DRC71_RS02765	COG0778	Nitroreductase
DRC71_RS02770	COG2357	RelA SpoT domain protein
DRC71_RS02810	COG1028	Short-chain dehydrogenase reductase Sdr
DRC71_RS02825	COG3835	regulator
DRC71_RS02830	COG2855	membrane
DRC71_RS02835	COG3961	Belongs to the TPP enzyme family
DRC71_RS02840	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
DRC71_RS02845	COG0512	Glutamine amidotransferase of anthranilate synthase
DRC71_RS02855	COG0134	indole-3-glycerol-phosphate synthase activity
DRC71_RS02865	COG0133	tryptophan synthase activity
DRC71_RS02870	COG0159	tryptophan synthase activity
DRC71_RS02890	COG0277	FAD linked oxidase domain protein
DRC71_RS02895	COG0247	lactate metabolic process
DRC71_RS02900	COG1132	(ABC) transporter
DRC71_RS02905	COG1132	(ABC) transporter
DRC71_RS02960	COG0741	lytic transglycosylase activity
DRC71_RS02960	COG0791	NLP P60 protein
DRC71_RS02990	COG2946	Replication initiation factor
DRC71_RS03000	COG1674	ftsk spoiiie
DRC71_RS03025	COG3871	stress protein (general stress protein 26)
DRC71_RS03030	COG1115	amino acid carrier protein
DRC71_RS03035	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
DRC71_RS03040	COG2814	Major facilitator Superfamily
DRC71_RS03045	COG2271	Major facilitator Superfamily
DRC71_RS03050	COG3764	Sortase (surface protein transpeptidase)
DRC71_RS03055	COG1929	Belongs to the glycerate kinase type-1 family
DRC71_RS03065	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
DRC71_RS03085	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
DRC71_RS03090	COG0702	epimerase
DRC71_RS03095	COG4166	transmembrane transport
DRC71_RS03100	COG0444	Belongs to the ABC transporter superfamily
DRC71_RS03105	COG4608	Belongs to the ABC transporter superfamily
DRC71_RS03110	COG0601	transmembrane transport
DRC71_RS03115	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DRC71_RS03120	COG4166	transmembrane transport
DRC71_RS03125	COG0444	Belongs to the ABC transporter superfamily
DRC71_RS03130	COG4608	Belongs to the ABC transporter superfamily
DRC71_RS03135	COG0601	transmembrane transport
DRC71_RS03140	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DRC71_RS03150	COG1760	l-serine dehydratase
DRC71_RS03155	COG1760	l-serine dehydratase
DRC71_RS03205	COG0471	metal ion transport
DRC71_RS03210	COG2116	formate transmembrane transporter activity
DRC71_RS03215	COG0454	-acetyltransferase
DRC71_RS03225	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
DRC71_RS03225	COG1648	precorrin-2 dehydrogenase activity
DRC71_RS03230	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
DRC71_RS03235	COG2146	nitrite reductase [NAD(P)H] activity
DRC71_RS03240	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
DRC71_RS03240	COG1648	precorrin-2 dehydrogenase activity
DRC71_RS03245	COG0737	Belongs to the 5'-nucleotidase family
DRC71_RS03255	COG0018	arginyl-trna synthetase
DRC71_RS03270	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
DRC71_RS03275	COG1140	nitrate reductase beta subunit
DRC71_RS03285	COG2181	nitrate reductase activity
DRC71_RS03295	COG4585	Histidine kinase
DRC71_RS03300	COG2197	response regulator
DRC71_RS03305	COG2223	nitrite transmembrane transporter activity
DRC71_RS03310	COG3344	reverse transcriptase
DRC71_RS03315	COG4187	Peptidase family M20/M25/M40
DRC71_RS03325	COG0039	L-malate dehydrogenase activity
DRC71_RS03330	COG1363	Peptidase, m42
DRC71_RS03335	COG0697	spore germination
DRC71_RS03345	COG2807	transmembrane transport
DRC71_RS03355	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DRC71_RS03355	COG1263	PTS System
DRC71_RS03370	COG1283	sodium-dependent phosphate transmembrane transporter activity
DRC71_RS03390	COG0492	ferredoxin-NADP+ reductase activity
DRC71_RS03395	COG2814	Major facilitator Superfamily
DRC71_RS03400	COG0604	alcohol dehydrogenase
DRC71_RS03415	COG1620	l-lactate permease
DRC71_RS03420	COG0438	transferase activity, transferring glycosyl groups
DRC71_RS03425	COG0579	oxidoreductase
DRC71_RS03440	COG0577	efflux transmembrane transporter activity
DRC71_RS03480	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
DRC71_RS03490	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DRC71_RS03510	COG1304	FMN binding
DRC71_RS03515	COG0523	cobalamin synthesis protein
DRC71_RS03520	COG0786	glutamate:sodium symporter activity
DRC71_RS03525	COG2207	Transcriptional regulator
DRC71_RS03550	COG1757	Na H antiporter
DRC71_RS03555	COG2094	Belongs to the DNA glycosylase MPG family
DRC71_RS03560	COG3152	Membrane
DRC71_RS03565	COG4152	abc transporter atp-binding protein
DRC71_RS03570	COG1668	transmembrane transport
DRC71_RS03575	COG1742	UPF0060 membrane protein
DRC71_RS03580	COG2017	converts alpha-aldose to the beta-anomer
DRC71_RS03585	COG2258	MOSC domain
DRC71_RS03590	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
DRC71_RS03600	COG1266	CAAX protease self-immunity
DRC71_RS03605	COG0583	DNA-binding transcription factor activity
DRC71_RS03610	COG3314	Sporulation integral membrane protein YlbJ
DRC71_RS03615	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
DRC71_RS03620	COG1228	amidohydrolase
DRC71_RS03625	COG0659	secondary active sulfate transmembrane transporter activity
DRC71_RS03630	COG1473	amidohydrolase
DRC71_RS03650	COG0385	Bile acid
DRC71_RS03660	COG0346	lactoylglutathione lyase activity
DRC71_RS03665	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DRC71_RS03690	COG1113	amino acid transport
DRC71_RS03715	COG1316	TRANSCRIPTIONal
DRC71_RS03730	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
DRC71_RS03735	COG3383	formate dehydrogenase (NAD+) activity
DRC71_RS03760	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DRC71_RS03765	COG2076	Multidrug Resistance protein
DRC71_RS03770	COG2076	Multidrug Resistance protein
DRC71_RS03775	COG3942	CHAP domain
DRC71_RS03785	COG1757	Na H antiporter
DRC71_RS03795	COG3942	CHAP domain
DRC71_RS03815	COG1960	acyl-CoA dehydrogenase activity
DRC71_RS03820	COG2832	Protein of unknown function (DUF454)
DRC71_RS03825	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
DRC71_RS03830	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DRC71_RS03840	COG2186	Transcriptional regulator
DRC71_RS03850	COG1268	BioY protein
DRC71_RS03865	COG1609	Transcriptional regulator
DRC71_RS03870	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
DRC71_RS03875	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
DRC71_RS03880	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
DRC71_RS03890	COG4149	molybdate abc transporter
DRC71_RS03895	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
DRC71_RS03900	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
DRC71_RS03905	COG0521	Mo-molybdopterin cofactor biosynthetic process
DRC71_RS03925	COG0314	molybdopterin synthase activity
DRC71_RS03935	COG0746	molybdenum cofactor guanylyltransferase activity
DRC71_RS03940	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
DRC71_RS03965	COG2348	transferase activity, transferring amino-acyl groups
DRC71_RS03970	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DRC71_RS03975	COG0436	Aminotransferase
DRC71_RS04005	COG2252	PERMEase
DRC71_RS04025	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
DRC71_RS04030	COG0088	Forms part of the polypeptide exit tunnel
DRC71_RS04035	COG0089	rRNA binding
DRC71_RS04040	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
DRC71_RS04045	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
DRC71_RS04050	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
DRC71_RS04055	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
DRC71_RS04060	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
DRC71_RS04065	COG0255	Belongs to the universal ribosomal protein uL29 family
DRC71_RS04075	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
DRC71_RS04090	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
DRC71_RS04095	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
DRC71_RS04100	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
DRC71_RS04110	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
DRC71_RS04115	COG1841	ribosomal large subunit assembly
DRC71_RS04125	COG0201	protein transport
DRC71_RS04140	COG0257	Belongs to the bacterial ribosomal protein bL36 family
DRC71_RS04150	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
DRC71_RS04155	COG0202	RNA polymerase activity
DRC71_RS04160	COG0203	ribosomal protein L17
DRC71_RS04165	COG1122	ATPase activity
DRC71_RS04170	COG1122	ATPase activity
DRC71_RS04180	COG0101	tRNA pseudouridine synthase activity
DRC71_RS04185	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
DRC71_RS04205	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
DRC71_RS04245	COG1349	DNA-binding transcription factor activity
DRC71_RS04260	COG3684	Belongs to the aldolase LacD family
DRC71_RS04270	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DRC71_RS04270	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DRC71_RS04280	COG3513	CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
DRC71_RS04285	COG1518	maintenance of DNA repeat elements
DRC71_RS04305	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
DRC71_RS04320	COG1302	Protein conserved in bacteria
DRC71_RS04325	COG2814	Major facilitator Superfamily
DRC71_RS04330	COG4264	IucA IucC family
DRC71_RS04335	COG2814	Major facilitator Superfamily
DRC71_RS04340	COG4264	IucA IucC family
DRC71_RS04345	COG3457	Alanine racemase
DRC71_RS04350	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
DRC71_RS04355	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DRC71_RS04360	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DRC71_RS04365	COG3314	Sporulation integral membrane protein YlbJ
DRC71_RS04375	COG1988	membrane-bound metal-dependent
DRC71_RS04380	COG4284	Utp--glucose-1-phosphate uridylyltransferase
DRC71_RS04385	COG1272	protein, Hemolysin III
DRC71_RS04405	COG2814	Major facilitator Superfamily
DRC71_RS04410	COG0489	protein tyrosine kinase activity
DRC71_RS04475	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DRC71_RS04495	COG1119	ATPase activity
DRC71_RS04500	COG0561	phosphatase activity
DRC71_RS04515	COG2186	Transcriptional regulator
DRC71_RS04520	COG1482	cell wall glycoprotein biosynthetic process
DRC71_RS04535	COG1757	Na H antiporter
DRC71_RS04545	COG0813	purine-nucleoside phosphorylase activity
DRC71_RS04580	COG5146	pantothenate kinase activity
DRC71_RS04595	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DRC71_RS04605	COG0504	CTP synthase activity
DRC71_RS04615	COG2271	Major facilitator Superfamily
DRC71_RS04620	COG4821	SIS domain
DRC71_RS04625	COG0191	fructose-bisphosphate aldolase activity
DRC71_RS04630	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
DRC71_RS04635	COG1733	regulation of RNA biosynthetic process
DRC71_RS04650	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
DRC71_RS04655	COG0254	rRNA binding
DRC71_RS04665	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
DRC71_RS04670	COG2890	protein-(glutamine-N5) methyltransferase activity
DRC71_RS04675	COG0009	L-threonylcarbamoyladenylate synthase
DRC71_RS04680	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DRC71_RS04685	COG4475	Protein of unknown function (DUF436)
DRC71_RS04690	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
DRC71_RS04695	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
DRC71_RS04700	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
DRC71_RS04710	COG0356	it plays a direct role in the translocation of protons across the membrane
DRC71_RS04715	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
DRC71_RS04725	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
DRC71_RS04735	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
DRC71_RS04765	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
DRC71_RS04780	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
DRC71_RS04790	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
DRC71_RS04795	COG0352	thiamine-phosphate diphosphorylase activity
DRC71_RS04800	COG0706	membrane insertase activity
DRC71_RS04805	COG1418	mRNA catabolic process
DRC71_RS04810	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DRC71_RS04815	COG1937	Protein conserved in bacteria
DRC71_RS04830	COG2217	Heavy metal translocating P-type atpase
DRC71_RS04850	COG0772	Belongs to the SEDS family
DRC71_RS04855	COG1181	Belongs to the D-alanine--D-alanine ligase family
DRC71_RS04860	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
DRC71_RS04865	COG0513	Belongs to the DEAD box helicase family
DRC71_RS04880	COG3402	PFAM membrane-flanked domain
DRC71_RS04885	COG0736	holo-[acyl-carrier-protein] synthase activity
DRC71_RS04890	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
DRC71_RS04900	COG2337	Toxic component of a toxin-antitoxin (TA) module
DRC71_RS04905	COG2208	phosphoserine phosphatase activity
DRC71_RS04910	COG1366	Belongs to the anti-sigma-factor antagonist family
DRC71_RS04920	COG1191	sigma factor activity
DRC71_RS04930	COG3091	SprT-like family
DRC71_RS04965	COG0515	serine threonine protein kinase
DRC71_RS04985	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
DRC71_RS04995	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DRC71_RS05000	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
DRC71_RS05010	COG0028	Belongs to the TPP enzyme family
DRC71_RS05015	COG0129	dihydroxy-acid dehydratase activity
DRC71_RS05020	COG0802	atpase or kinase
DRC71_RS05025	COG1214	PFAM Peptidase M22, glycoprotease
DRC71_RS05030	COG0456	acetyltransferase
DRC71_RS05035	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
DRC71_RS05045	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
DRC71_RS05050	COG0488	(ABC) transporter
DRC71_RS05055	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
DRC71_RS05060	COG2814	Major facilitator Superfamily
DRC71_RS05065	COG1846	Transcriptional regulator
DRC71_RS05075	COG2124	cytochrome p450
DRC71_RS05085	COG1609	Transcriptional regulator
DRC71_RS05090	COG1621	beta-fructofuranosidase activity
DRC71_RS05095	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DRC71_RS05115	COG4512	PFAM Accessory gene regulator B
DRC71_RS05155	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DRC71_RS05160	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
DRC71_RS05180	COG1131	(ABC) transporter
DRC71_RS05195	COG1070	Carbohydrate kinase
DRC71_RS05200	COG2610	gluconate transmembrane transporter activity
DRC71_RS05235	COG2706	6-phosphogluconolactonase activity
DRC71_RS05240	COG1012	belongs to the aldehyde dehydrogenase family
DRC71_RS05250	COG1227	inorganic diphosphatase activity
DRC71_RS05255	COG1335	isochorismatase
DRC71_RS05265	COG0077	Prephenate dehydratase
DRC71_RS05275	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
DRC71_RS05285	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
DRC71_RS05295	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
DRC71_RS05300	COG4496	protein, YerC YecD
DRC71_RS05305	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
DRC71_RS05310	COG0210	DNA helicase
DRC71_RS05315	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
DRC71_RS05320	COG4851	CamS sex pheromone cAM373 precursor
DRC71_RS05325	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DRC71_RS05330	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DRC71_RS05340	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DRC71_RS05345	COG1597	lipid kinase activity
DRC71_RS05370	COG0488	(ABC) transporter
DRC71_RS05380	COG1396	sequence-specific DNA binding
DRC71_RS05390	COG2211	Major facilitator Superfamily
DRC71_RS05400	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DRC71_RS05410	COG1528	Iron-storage protein
DRC71_RS05425	COG4129	membrane
DRC71_RS05430	COG0024	Methionine aminopeptidase
DRC71_RS05455	COG0288	reversible hydration of carbon dioxide
DRC71_RS05460	COG1295	ribonuclease BN
DRC71_RS05475	COG4840	Belongs to the UPF0435 family
DRC71_RS05480	COG2309	aminopeptidase activity
DRC71_RS05485	COG1607	acyl-coa hydrolase
DRC71_RS05490	COG0535	radical SAM domain protein
DRC71_RS05500	COG0693	protein deglycase activity
DRC71_RS05505	COG0028	Belongs to the TPP enzyme family
DRC71_RS05510	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DRC71_RS05515	COG2137	regulation of response to DNA damage stimulus
DRC71_RS05525	COG1388	LysM domain
DRC71_RS05525	COG1134	teichoic acid transport
DRC71_RS05535	COG1988	membrane-bound metal-dependent
DRC71_RS05540	COG1194	a g-specific adenine glycosylase
DRC71_RS05545	COG3557	Belongs to the UPF0374 family
DRC71_RS05555	COG0069	glutamate synthase activity
DRC71_RS05560	COG4129	membrane
DRC71_RS05565	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
DRC71_RS05570	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
DRC71_RS05580	COG0735	belongs to the Fur family
DRC71_RS05805	COG0765	amino acid transport
DRC71_RS05810	COG1126	abc transporter atp-binding protein
DRC71_RS05815	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
DRC71_RS05825	COG0363	glucosamine-6-phosphate deaminase activity
DRC71_RS05840	COG0114	fumarate hydratase activity
DRC71_RS05845	COG0248	Ppx GppA phosphatase
DRC71_RS05850	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
DRC71_RS05855	COG0564	pseudouridine synthase activity
DRC71_RS05860	COG2203	Gaf domain
DRC71_RS05860	COG4585	Histidine kinase
DRC71_RS05865	COG2197	response regulator
DRC71_RS05875	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
DRC71_RS05885	COG4399	Belongs to the UPF0754 family
DRC71_RS05890	COG3679	Belongs to the UPF0342 family
DRC71_RS05895	COG0420	3'-5' exonuclease activity
DRC71_RS05905	COG3481	metal-dependent phosphohydrolase, HD sub domain
DRC71_RS05910	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
DRC71_RS05925	COG1846	Transcriptional regulator
DRC71_RS05935	COG0537	adenosine 5'-monophosphoramidase activity
DRC71_RS05940	COG1131	(ABC) transporter
DRC71_RS05945	COG4473	ABC transporter
DRC71_RS05960	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
DRC71_RS05970	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
DRC71_RS05975	COG3545	Serine hydrolase
DRC71_RS06035	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
DRC71_RS06235	COG0739	heme binding
DRC71_RS06275	COG5632	N-Acetylmuramoyl-L-alanine amidase
DRC71_RS06275	COG1388	LysM domain
DRC71_RS06340	COG3037	sugar-specific permease SgaT UlaA
DRC71_RS06360	COG3623	hexulose-6-phosphate isomerase
DRC71_RS06365	COG0235	Class ii aldolase
DRC71_RS06385	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
DRC71_RS06390	COG0494	nUDIX hydrolase
DRC71_RS06395	COG1506	peptidase
DRC71_RS06400	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
DRC71_RS06405	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
DRC71_RS06415	COG0656	L-ascorbic acid biosynthetic process
DRC71_RS06420	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
DRC71_RS06425	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
DRC71_RS06435	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
DRC71_RS06460	COG5632	N-Acetylmuramoyl-L-alanine amidase
DRC71_RS06460	COG4193	domain, Protein
DRC71_RS06460	COG3266	domain, Protein
DRC71_RS06470	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
DRC71_RS06470	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
DRC71_RS06475	COG0307	riboflavin synthase, alpha
DRC71_RS06480	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
DRC71_RS06480	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
DRC71_RS06485	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
DRC71_RS06500	COG2267	carboxylic ester hydrolase activity
DRC71_RS06505	COG0039	L-malate dehydrogenase activity
DRC71_RS06515	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
DRC71_RS06520	COG1242	4 iron, 4 sulfur cluster binding
DRC71_RS06525	COG2814	Major facilitator Superfamily
DRC71_RS06530	COG0495	leucyl-tRNA aminoacylation
DRC71_RS06535	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
DRC71_RS06540	COG2081	HI0933 family
DRC71_RS06545	COG2244	polysaccharide biosynthetic process
DRC71_RS06550	COG1187	pseudouridine synthase activity
DRC71_RS06560	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DRC71_RS06565	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
DRC71_RS06570	COG0510	thiamine kinase activity
DRC71_RS06575	COG0220	tRNA (guanine-N7-)-methyltransferase activity
DRC71_RS06590	COG1363	Peptidase, m42
DRC71_RS06595	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DRC71_RS06600	COG4848	Belongs to the UPF0354 family
DRC71_RS06605	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DRC71_RS06610	COG1674	ftsk spoiiie
DRC71_RS06615	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
DRC71_RS06620	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
DRC71_RS06630	COG1605	Chorismate mutase
DRC71_RS06630	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
DRC71_RS06635	COG1609	Transcriptional regulator
DRC71_RS06645	COG0454	-acetyltransferase
DRC71_RS06650	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DRC71_RS06655	COG2759	Belongs to the formate--tetrahydrofolate ligase family
DRC71_RS06660	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
DRC71_RS06670	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DRC71_RS06675	COG0204	Acyl-transferase
DRC71_RS06685	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
DRC71_RS06690	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
DRC71_RS06695	COG1764	response to oxidative stress
DRC71_RS06735	COG0456	acetyltransferase
DRC71_RS06770	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
DRC71_RS06775	COG1956	GAF domain-containing protein
DRC71_RS06780	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
DRC71_RS06785	COG1104	cysteine desulfurase activity
DRC71_RS06790	COG0301	tRNA thio-modification
DRC71_RS06800	COG0616	signal peptide processing
DRC71_RS06805	COG1714	RDD family
DRC71_RS06810	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
DRC71_RS06815	COG0827	DNA restriction-modification system
DRC71_RS06820	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
DRC71_RS06825	COG0589	response to stress
DRC71_RS06830	COG0686	Belongs to the AlaDH PNT family
DRC71_RS06840	COG0006	proline dipeptidase activity
DRC71_RS06845	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
DRC71_RS06855	COG4109	DRTGG domain
DRC71_RS06860	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
DRC71_RS06865	COG0587	DNA-directed DNA polymerase activity
DRC71_RS06870	COG0281	malic enzyme
DRC71_RS06875	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
DRC71_RS06880	COG0825	malonyl-CoA metabolic process
DRC71_RS06890	COG0205	6-phosphofructokinase activity
DRC71_RS06895	COG0469	pyruvate kinase activity
DRC71_RS06900	COG0372	Belongs to the citrate synthase family
DRC71_RS06905	COG0538	isocitrate dehydrogenase activity
DRC71_RS06910	COG0745	RESPONSE REGULATOR receiver
DRC71_RS06915	COG5002	protein histidine kinase activity
DRC71_RS06920	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DRC71_RS06920	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DRC71_RS06930	COG0237	dephospho-CoA kinase activity
DRC71_RS06945	COG3611	Membrane attachment protein
DRC71_RS06950	COG1484	DNA-dependent DNA replication
DRC71_RS06960	COG0833	amino acid
DRC71_RS06970	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
DRC71_RS06975	COG0291	Belongs to the bacterial ribosomal protein bL35 family
DRC71_RS06980	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
DRC71_RS06995	COG0544	peptidyl-prolyl cis-trans isomerase activity
DRC71_RS07005	COG0218	Necessary for normal cell division and for the maintenance of normal septation
DRC71_RS07010	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
DRC71_RS07020	COG0181	hydroxymethylbilane synthase activity
DRC71_RS07035	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
DRC71_RS07045	COG2818	Glycosylase
DRC71_RS07050	COG0525	valine-tRNA ligase activity
DRC71_RS07055	COG0285	dihydrofolate synthase activity
DRC71_RS07065	COG2003	Belongs to the UPF0758 family
DRC71_RS07100	COG2868	ribosomal protein
DRC71_RS07110	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
DRC71_RS07120	COG0632	four-way junction helicase activity
DRC71_RS07130	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
DRC71_RS07140	COG1862	Preprotein translocase
DRC71_RS07145	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DRC71_RS07145	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DRC71_RS07150	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
DRC71_RS07150	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
DRC71_RS07155	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
DRC71_RS07165	COG1490	D-aminoacyl-tRNA deacylase activity
DRC71_RS07170	COG0860	N-Acetylmuramoyl-L-alanine amidase
DRC71_RS07180	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
DRC71_RS07190	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
DRC71_RS07195	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
DRC71_RS07200	COG1959	2 iron, 2 sulfur cluster binding
DRC71_RS07215	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DRC71_RS07220	COG1104	cysteine desulfurase activity
DRC71_RS07225	COG0482	sulfurtransferase activity
DRC71_RS07235	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
DRC71_RS07240	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
DRC71_RS07245	COG4472	Bacterial protein of unknown function (DUF965)
DRC71_RS07250	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
DRC71_RS07255	COG3906	Belongs to the UPF0473 family
DRC71_RS07260	COG4122	O-methyltransferase activity
DRC71_RS07265	COG0826	peptidase U32
DRC71_RS07270	COG0826	peptidase U32
DRC71_RS07275	COG0572	uridine kinase
DRC71_RS07285	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
DRC71_RS07290	COG1984	allophanate hydrolase subunit 2
DRC71_RS07295	COG0511	ligase activity, forming carbon-carbon bonds
DRC71_RS07300	COG0439	Biotin carboxylase
DRC71_RS07305	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
DRC71_RS07310	COG1914	H( )-stimulated, divalent metal cation uptake system
DRC71_RS07315	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
DRC71_RS07320	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
DRC71_RS07325	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
DRC71_RS07330	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
DRC71_RS07335	COG1534	Rna-binding protein
DRC71_RS07345	COG1713	HD superfamily hydrolase involved in NAD metabolism
DRC71_RS07350	COG0799	negative regulation of ribosome biogenesis
DRC71_RS07355	COG2226	methyltransferase
DRC71_RS07360	COG1555	photosystem II stabilization
DRC71_RS07360	COG1596	polysaccharide export
DRC71_RS07365	COG2131	deaminase
DRC71_RS07370	COG0658	competence protein
DRC71_RS07370	COG2333	competence protein COMEC
DRC71_RS07375	COG1466	dna polymerase III delta subunit
DRC71_RS07380	COG0268	Binds directly to 16S ribosomal RNA
DRC71_RS07390	COG0635	Involved in the biosynthesis of porphyrin-containing compound
DRC71_RS07405	COG0443	Heat shock 70 kDa protein
DRC71_RS07410	COG0484	heat shock protein binding
DRC71_RS07415	COG2264	protein methyltransferase activity
DRC71_RS07420	COG1385	rRNA (uridine-N3-)-methyltransferase activity
DRC71_RS07425	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
DRC71_RS07440	COG1030	water channel activity
DRC71_RS07445	COG4864	UPF0365 protein
DRC71_RS07455	COG1702	phosphate starvation-inducible protein PhoH
DRC71_RS07465	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
DRC71_RS07475	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
DRC71_RS07480	COG1381	Involved in DNA repair and RecF pathway recombination
DRC71_RS07485	COG0423	glycine-tRNA ligase activity
DRC71_RS07490	COG0517	IMP dehydrogenase activity
DRC71_RS07495	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
DRC71_RS07500	COG0358	DNA primase activity
DRC71_RS07505	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
DRC71_RS07510	COG2384	SAM-dependent methyltransferase
DRC71_RS07515	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
DRC71_RS07520	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
DRC71_RS07525	COG0513	Belongs to the DEAD box helicase family
DRC71_RS07530	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
DRC71_RS07535	COG1121	(ABC) transporter
DRC71_RS07540	COG1108	ABC-type Mn2 Zn2 transport systems permease components
DRC71_RS07545	COG0735	belongs to the Fur family
DRC71_RS07550	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
DRC71_RS07560	COG0768	penicillin binding
DRC71_RS07565	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
DRC71_RS07570	COG0573	inorganic phosphate transmembrane transporter activity
DRC71_RS07575	COG0581	inorganic phosphate transmembrane transporter activity
DRC71_RS07580	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
DRC71_RS07585	COG0704	Plays a role in the regulation of phosphate uptake
DRC71_RS07595	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
DRC71_RS07600	COG0457	Tetratricopeptide repeat
DRC71_RS07600	COG0705	Rhomboid family
DRC71_RS07605	COG4483	Protein conserved in bacteria
DRC71_RS07610	COG1940	carbohydrate kinase activity
DRC71_RS07615	COG0011	TIGRFAM Protein of
DRC71_RS07620	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DRC71_RS07625	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
DRC71_RS07655	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
DRC71_RS07660	COG0404	The glycine cleavage system catalyzes the degradation of glycine
DRC71_RS07670	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
DRC71_RS07675	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
DRC71_RS07680	COG0095	Lipoate-protein ligase
DRC71_RS07695	COG0006	proline dipeptidase activity
DRC71_RS07700	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
DRC71_RS07705	COG0511	ligase activity, forming carbon-carbon bonds
DRC71_RS07710	COG0439	Biotin carboxylase
DRC71_RS07715	COG1302	Protein conserved in bacteria
DRC71_RS07725	COG1570	exodeoxyribonuclease VII activity
DRC71_RS07730	COG1722	exodeoxyribonuclease VII activity
DRC71_RS07735	COG0142	geranyltranstransferase activity
DRC71_RS07740	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
DRC71_RS07745	COG1438	arginine binding
DRC71_RS07750	COG0497	DNA recombination
DRC71_RS07755	COG0280	phosphate acetyltransferase
DRC71_RS07760	COG3426	butyrate kinase activity
DRC71_RS07765	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DRC71_RS07770	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
DRC71_RS07775	COG0022	dehydrogenase e1 component
DRC71_RS07780	COG0508	dehydrogenase complex catalyzes the overall conversion of
DRC71_RS07790	COG4129	membrane
DRC71_RS07800	COG2195	Cleaves the N-terminal amino acid of tripeptides
DRC71_RS07830	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
DRC71_RS07835	COG1234	tRNA 3'-trailer cleavage
DRC71_RS07840	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
DRC71_RS07850	COG0667	Aldo Keto reductase
DRC71_RS07855	COG0494	nUDIX hydrolase
DRC71_RS07860	COG0735	belongs to the Fur family
DRC71_RS07875	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
DRC71_RS07880	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
DRC71_RS07885	COG1187	pseudouridine synthase activity
DRC71_RS07890	COG0745	RESPONSE REGULATOR receiver
DRC71_RS07905	COG1141	Ferredoxin
DRC71_RS07915	COG0514	ATP-dependent DNA helicase (RecQ)
DRC71_RS07925	COG0492	ferredoxin-NADP+ reductase activity
DRC71_RS07930	COG0252	asparaginase activity
DRC71_RS07940	COG0539	negative regulation of cytoplasmic translation
DRC71_RS07945	COG1160	GTP binding
DRC71_RS07950	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
DRC71_RS07970	COG0142	geranyltranstransferase activity
DRC71_RS07975	COG0105	UTP biosynthetic process
DRC71_RS07985	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
DRC71_RS07995	COG0457	Tetratricopeptide repeat
DRC71_RS08000	COG5582	Belongs to the UPF0302 family
DRC71_RS08005	COG4347	Protein of unknown function (DUF1405)
DRC71_RS08015	COG1694	Mazg nucleotide pyrophosphohydrolase
DRC71_RS08020	COG0438	transferase activity, transferring glycosyl groups
DRC71_RS08025	COG0617	tRNA 3'-terminal CCA addition
DRC71_RS08040	COG0017	Asparaginyl-tRNA synthetase
DRC71_RS08045	COG3935	DnaD domain protein
DRC71_RS08050	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
DRC71_RS08060	COG4499	WXG100 protein secretion system (Wss), protein YukC
DRC71_RS08060	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DRC71_RS08075	COG4474	Belongs to the UPF0398 family
DRC71_RS08080	COG3599	regulation of cell shape
DRC71_RS08090	COG0116	Belongs to the methyltransferase superfamily
DRC71_RS08095	COG2962	Rard protein
DRC71_RS08100	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
DRC71_RS08105	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DRC71_RS08115	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
DRC71_RS08125	COG1413	lyase activity
DRC71_RS08160	COG2190	(PTS) system
DRC71_RS08170	COG0793	Belongs to the peptidase S41A family
DRC71_RS08180	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
DRC71_RS08185	COG0671	phosphoesterase, PA-phosphatase related
DRC71_RS08195	COG5002	protein histidine kinase activity
DRC71_RS08200	COG0567	Dehydrogenase, E1 component
DRC71_RS08225	COG0714	Associated with various cellular activities
DRC71_RS08230	COG4548	von Willebrand factor, type A
DRC71_RS08235	COG1114	Component of the transport system for branched-chain amino acids
DRC71_RS08240	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
DRC71_RS08245	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
DRC71_RS08255	COG3853	Toxic anion resistance protein (TelA)
DRC71_RS08275	COG1278	Cold shock
DRC71_RS08295	COG1473	amidohydrolase
DRC71_RS08300	COG2171	N-acyltransferase activity
DRC71_RS08305	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
DRC71_RS08310	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DRC71_RS08315	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
DRC71_RS08320	COG0488	(ABC) transporter
DRC71_RS08325	COG2996	Protein conserved in bacteria
DRC71_RS08355	COG1363	Peptidase, m42
DRC71_RS08360	COG0287	Prephenate dehydrogenase
DRC71_RS08365	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DRC71_RS08375	COG1942	4-Oxalocrotonate Tautomerase
DRC71_RS08395	COG0628	permease
DRC71_RS08405	COG3711	transcriptional antiterminator
DRC71_RS08410	COG1115	amino acid carrier protein
DRC71_RS08415	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
DRC71_RS08425	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
DRC71_RS08430	COG4841	protein insertion into membrane
DRC71_RS08435	COG0824	Thioesterase
DRC71_RS08445	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
DRC71_RS08450	COG1970	mechanosensitive ion channel activity
DRC71_RS08455	COG0419	ATPase involved in DNA repair
DRC71_RS08460	COG0420	3'-5' exonuclease activity
DRC71_RS08465	COG4846	Membrane protein involved in cytochrome C biogenesis
DRC71_RS08470	COG3763	UPF0154 protein
DRC71_RS08480	COG4224	UPF0291 protein
DRC71_RS08490	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
DRC71_RS08500	COG0516	GMP reductase activity
DRC71_RS08505	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
DRC71_RS08515	COG0833	amino acid
DRC71_RS08530	COG0083	homoserine kinase activity
DRC71_RS08535	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
DRC71_RS08540	COG0460	homoserine dehydrogenase
DRC71_RS08545	COG0527	aspartate kinase activity
DRC71_RS08570	COG1525	nuclease
DRC71_RS08600	COG0584	glycerophosphoryl diester phosphodiesterase
DRC71_RS08620	COG0789	Transcriptional regulator
DRC71_RS08625	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
DRC71_RS08630	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
DRC71_RS08635	COG0386	Belongs to the glutathione peroxidase family
DRC71_RS08640	COG2267	carboxylic ester hydrolase activity
DRC71_RS08645	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
DRC71_RS08650	COG1923	regulation of RNA biosynthetic process
DRC71_RS08655	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
DRC71_RS08665	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
DRC71_RS08670	COG1619	proteins homologs of microcin C7 resistance protein MccF
DRC71_RS08675	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
DRC71_RS08680	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
DRC71_RS08700	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
DRC71_RS08710	COG1013	pyruvate-flavodoxin oxidoreductase activity
DRC71_RS08715	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
DRC71_RS08715	COG0674	pyruvate-flavodoxin oxidoreductase activity
DRC71_RS08720	COG1692	metallophosphoesterase
DRC71_RS08740	COG1418	mRNA catabolic process
DRC71_RS08745	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
DRC71_RS08750	COG1058	Belongs to the CinA family
DRC71_RS08750	COG1546	Belongs to the CinA family
DRC71_RS08770	COG0300	oxidoreductase activity
DRC71_RS08775	COG0612	Peptidase, M16
DRC71_RS08780	COG0612	Peptidase, M16
DRC71_RS08785	COG2188	Transcriptional regulator
DRC71_RS08810	COG0196	riboflavin kinase activity
DRC71_RS08815	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
DRC71_RS08820	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
DRC71_RS08830	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
DRC71_RS08835	COG1358	cellular component organization or biogenesis
DRC71_RS08840	COG2740	Nucleic-acid-binding protein implicated in transcription termination
DRC71_RS08845	COG0195	Participates in both transcription termination and antitermination
DRC71_RS08850	COG0779	Required for maturation of 30S ribosomal subunits
DRC71_RS08860	COG0442	prolyl-tRNA aminoacylation
DRC71_RS08870	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
DRC71_RS08875	COG4589	Belongs to the CDS family
DRC71_RS08880	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
DRC71_RS08885	COG0233	cytoplasmic translational termination
DRC71_RS08890	COG0528	UMP kinase activity
DRC71_RS08895	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
DRC71_RS08900	COG0052	Belongs to the universal ribosomal protein uS2 family
DRC71_RS08905	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
DRC71_RS08910	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
DRC71_RS08915	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
DRC71_RS08920	COG4974	Belongs to the 'phage' integrase family
DRC71_RS08925	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
DRC71_RS08930	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
DRC71_RS08935	COG0758	DNA mediated transformation
DRC71_RS08945	COG0045	succinate-CoA ligase (ADP-forming) activity
DRC71_RS08955	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
DRC71_RS08970	COG4485	Bacterial membrane protein, YfhO
DRC71_RS09010	COG0336	Belongs to the RNA methyltransferase TrmD family
DRC71_RS09015	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
DRC71_RS09020	COG0228	four-way junction DNA binding
DRC71_RS09030	COG1401	restriction endodeoxyribonuclease activity
DRC71_RS09050	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
DRC71_RS09055	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
DRC71_RS09060	COG0552	protein localization to endoplasmic reticulum
DRC71_RS09065	COG1196	nuclear chromosome segregation
DRC71_RS09070	COG0571	ribonuclease III activity
DRC71_RS09075	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DRC71_RS09090	COG0416	fatty acid biosynthetic process
DRC71_RS09095	COG1349	DNA-binding transcription factor activity
DRC71_RS09105	COG1760	l-serine dehydratase
DRC71_RS09110	COG1760	l-serine dehydratase
DRC71_RS09120	COG1302	Protein conserved in bacteria
DRC71_RS09135	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
DRC71_RS09140	COG1162	GTPase activity
DRC71_RS09150	COG2124	cytochrome p450
DRC71_RS09165	COG0820	rRNA (adenine-C2-)-methyltransferase activity
DRC71_RS09170	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
DRC71_RS09170	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
DRC71_RS09175	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
DRC71_RS09180	COG0242	peptide deformylase activity
DRC71_RS09185	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
DRC71_RS09190	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
DRC71_RS09205	COG1758	RNA polymerase activity
DRC71_RS09225	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
DRC71_RS09230	COG0284	orotidine-5'-phosphate decarboxylase activity
DRC71_RS09235	COG0167	dihydroorotate dehydrogenase activity
DRC71_RS09250	COG0505	Belongs to the CarA family
DRC71_RS09270	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
DRC71_RS09275	COG0564	pseudouridine synthase activity
DRC71_RS09280	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
DRC71_RS09285	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
DRC71_RS09290	COG3599	regulation of cell shape
DRC71_RS09300	COG0673	inositol 2-dehydrogenase activity
DRC71_RS09305	COG4409	exo-alpha-(2->6)-sialidase activity
DRC71_RS09315	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DRC71_RS09320	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DRC71_RS09330	COG4975	Glucose uptake
DRC71_RS09335	COG1869	D-ribose catabolic process
DRC71_RS09340	COG0762	integral membrane protein
DRC71_RS09345	COG1799	cell septum assembly
DRC71_RS09350	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
DRC71_RS09360	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
DRC71_RS09365	COG0849	cell division
DRC71_RS09375	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
DRC71_RS09385	COG0768	penicillin binding
DRC71_RS09390	COG4839	cell division protein FtsL
DRC71_RS09395	COG0275	rRNA processing
DRC71_RS09400	COG2001	Belongs to the MraZ family
DRC71_RS09405	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
DRC71_RS09410	COG0454	-acetyltransferase
DRC71_RS09415	COG1011	Hydrolase
DRC71_RS09430	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
DRC71_RS09495	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
DRC71_RS09500	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
DRC71_RS09505	COG1053	succinate dehydrogenase
DRC71_RS09510	COG2009	succinate dehydrogenase
DRC71_RS09515	COG0322	excinuclease ABC activity
DRC71_RS09520	COG3118	belongs to the thioredoxin family
DRC71_RS09525	COG1193	negative regulation of DNA recombination
DRC71_RS09530	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
DRC71_RS09530	COG1796	DNA polymerase
DRC71_RS09545	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
DRC71_RS09565	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
DRC71_RS09570	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DRC71_RS09575	COG0333	Belongs to the bacterial ribosomal protein bL32 family
DRC71_RS09595	COG0742	ribosomal rna small subunit methyltransferase
DRC71_RS09605	COG4471	UPF0298 protein
DRC71_RS09610	COG0584	glycerophosphoryl diester phosphodiesterase
DRC71_RS09615	COG3679	Belongs to the UPF0342 family
DRC71_RS09630	COG0109	protoheme IX farnesyltransferase activity
DRC71_RS09655	COG0772	Belongs to the SEDS family
DRC71_RS09660	COG4838	Belongs to the UPF0358 family
DRC71_RS09665	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
DRC71_RS09670	COG4896	Protein conserved in bacteria
DRC71_RS09675	COG1902	pentaerythritol trinitrate reductase activity
DRC71_RS09680	COG1217	gtp-binding protein TYPA
DRC71_RS09690	COG0483	inositol monophosphate 1-phosphatase activity
DRC71_RS09695	COG4493	Belongs to the UPF0637 family
DRC71_RS09710	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
DRC71_RS09715	COG1177	transmembrane transport
DRC71_RS09725	COG3842	ATPase activity
DRC71_RS09735	COG4476	Belongs to the UPF0223 family
DRC71_RS09775	COG5503	Protein of unknown function (DUF1447)
DRC71_RS09780	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
DRC71_RS09790	COG0492	ferredoxin-NADP+ reductase activity
DRC71_RS09815	COG0569	domain protein
DRC71_RS09820	COG1294	oxidase, subunit
DRC71_RS09825	COG1271	oxidase subunit
DRC71_RS09830	COG1393	Belongs to the ArsC family
DRC71_RS09835	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DRC71_RS09840	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
DRC71_RS09850	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
DRC71_RS09865	COG4172	Belongs to the ABC transporter superfamily
DRC71_RS09875	COG0151	Belongs to the GarS family
DRC71_RS09880	COG0138	bifunctional purine biosynthesis protein purh
DRC71_RS09890	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
DRC71_RS09895	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
DRC71_RS09905	COG0047	phosphoribosylformylglycinamidine synthase activity
DRC71_RS09910	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
DRC71_RS09915	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
DRC71_RS09920	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
DRC71_RS09925	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
DRC71_RS09930	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
DRC71_RS09935	COG1017	nitric oxide dioxygenase activity
DRC71_RS09935	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
DRC71_RS09945	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
DRC71_RS09955	COG1845	cytochrome c oxidase, subunit III
DRC71_RS09960	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
DRC71_RS09970	COG3973	AAA domain
DRC71_RS10010	COG3212	peptidase
DRC71_RS10025	COG1134	teichoic acid transport
DRC71_RS10035	COG1682	transport, permease protein
DRC71_RS10045	COG1215	transferase activity, transferring glycosyl groups
DRC71_RS10055	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
DRC71_RS10060	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DRC71_RS10065	COG1316	TRANSCRIPTIONal
DRC71_RS10090	COG3594	Acyltransferase
DRC71_RS10095	COG0436	Aminotransferase
DRC71_RS10100	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
DRC71_RS10110	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
DRC71_RS10115	COG1169	isochorismate synthase
DRC71_RS10120	COG1575	Belongs to the MenA family. Type 1 subfamily
DRC71_RS10125	COG0390	transport system, permease component
DRC71_RS10130	COG4619	ABC transporter
DRC71_RS10150	COG4873	Protein conserved in bacteria
DRC71_RS10230	COG2378	regulation of single-species biofilm formation
DRC71_RS10240	COG0456	acetyltransferase
DRC71_RS10250	COG2226	methyltransferase
DRC71_RS10290	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
DRC71_RS10290	COG0551	DNA topoisomerase type I activity
DRC71_RS10335	COG0737	Belongs to the 5'-nucleotidase family
DRC71_RS10345	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DRC71_RS10350	COG1696	Membrane protein involved in D-alanine export
DRC71_RS10360	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
DRC71_RS10365	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
DRC71_RS10375	COG0861	Integral membrane protein TerC family
DRC71_RS10380	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
DRC71_RS10390	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
DRC71_RS10395	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
DRC71_RS10400	COG2814	Major facilitator Superfamily
DRC71_RS10410	COG3715	PTS system
DRC71_RS10415	COG3716	PTS system mannose fructose sorbose family IID component
DRC71_RS10420	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
DRC71_RS10425	COG2382	esterase
DRC71_RS10430	COG1115	amino acid carrier protein
DRC71_RS10435	COG0628	permease
DRC71_RS10445	COG0475	glutathione-regulated potassium exporter activity
DRC71_RS10445	COG0569	domain protein
DRC71_RS10450	COG2239	Acts as a magnesium transporter
DRC71_RS10455	COG0564	pseudouridine synthase activity
DRC71_RS10465	COG2357	RelA SpoT domain protein
DRC71_RS10480	COG2346	COG2346, Truncated hemoglobins
DRC71_RS10485	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
DRC71_RS10495	COG1164	Oligoendopeptidase f
DRC71_RS10510	COG3591	Belongs to the peptidase S1B family
DRC71_RS10520	COG1393	Belongs to the ArsC family
DRC71_RS10525	COG0180	Tryptophanyl-tRNA synthetase
DRC71_RS10530	COG4166	transmembrane transport
DRC71_RS10535	COG4608	Belongs to the ABC transporter superfamily
DRC71_RS10540	COG0444	Belongs to the ABC transporter superfamily
DRC71_RS10545	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DRC71_RS10550	COG0601	transmembrane transport
DRC71_RS10580	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
DRC71_RS10600	COG0561	phosphatase activity
DRC71_RS10605	COG0446	pyridine nucleotide-disulphide oxidoreductase
DRC71_RS10615	COG0179	Fumarylacetoacetate (FAA) hydrolase
DRC71_RS10625	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
DRC71_RS10640	COG0166	Belongs to the GPI family
DRC71_RS10645	COG0137	argininosuccinate synthase activity
DRC71_RS10655	COG0584	glycerophosphoryl diester phosphodiesterase
DRC71_RS10670	COG1012	belongs to the aldehyde dehydrogenase family
DRC71_RS10675	COG1098	S1 RNA binding domain
DRC71_RS10685	COG1278	Cold shock
DRC71_RS10705	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
DRC71_RS10720	COG2111	Na H antiporter
DRC71_RS10725	COG1006	Multisubunit Na H antiporter MnhC subunit
DRC71_RS10730	COG0651	ATP synthesis coupled electron transport
DRC71_RS10735	COG1863	multisubunit Na H antiporter MnhE subunit
DRC71_RS10740	COG2212	antiporter activity
DRC71_RS10745	COG1320	monovalent cation:proton antiporter activity
DRC71_RS10755	COG2056	Na+-H+ antiporter family
DRC71_RS10760	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
DRC71_RS10765	COG1252	NADH dehydrogenase
DRC71_RS10770	COG0316	Belongs to the HesB IscA family
DRC71_RS10775	COG4844	belongs to the
DRC71_RS10780	COG1252	NADH dehydrogenase
DRC71_RS10785	COG4837	Protein of unknown function (DUF1462)
DRC71_RS10790	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
DRC71_RS10795	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DRC71_RS10800	COG0647	UMP catabolic process
DRC71_RS10805	COG2445	Protein of unknown function DUF86
DRC71_RS10815	COG4470	Protein conserved in bacteria
DRC71_RS10820	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
DRC71_RS10825	COG0737	Belongs to the 5'-nucleotidase family
DRC71_RS10830	COG0730	response to heat
DRC71_RS10835	COG1801	Protein of unknown function DUF72
DRC71_RS10850	COG1253	flavin adenine dinucleotide binding
DRC71_RS11010	COG2226	methyltransferase
DRC71_RS11080	COG1484	DNA-dependent DNA replication
DRC71_RS11210	COG0719	Fe-S assembly protein
DRC71_RS11215	COG0822	iron-sulfur transferase activity
DRC71_RS11225	COG0719	Fe-S assembly protein
DRC71_RS11230	COG0396	ATPase activity
DRC71_RS11240	COG1464	Belongs to the NlpA lipoprotein family
DRC71_RS11245	COG1464	Belongs to the NlpA lipoprotein family
DRC71_RS11250	COG2011	ABC-type metal ion transport system permease component
DRC71_RS11255	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
DRC71_RS11260	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DRC71_RS11265	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
DRC71_RS11275	COG1393	Belongs to the ArsC family
DRC71_RS11280	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DRC71_RS11290	COG0710	3-dehydroquinate dehydratase activity
DRC71_RS11300	COG1764	response to oxidative stress
DRC71_RS11315	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
DRC71_RS11335	COG0346	lactoylglutathione lyase activity
DRC71_RS11365	COG0557	exoribonuclease II activity
DRC71_RS11370	COG1647	Serine aminopeptidase, S33
DRC71_RS11375	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
DRC71_RS11400	COG0148	phosphopyruvate hydratase activity
DRC71_RS11405	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
DRC71_RS11435	COG1090	epimerase
DRC71_RS11445	COG0740	serine-type endopeptidase activity
DRC71_RS11455	COG1481	regulation of sporulation
DRC71_RS11460	COG0391	Required for morphogenesis under gluconeogenic growth conditions
DRC71_RS11465	COG1660	Displays ATPase and GTPase activities
DRC71_RS11480	COG0110	maltose O-acetyltransferase activity
DRC71_RS11485	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
DRC71_RS11490	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
DRC71_RS11525	COG0653	protein targeting
DRC71_RS11540	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
DRC71_RS11550	COG1739	Uncharacterized protein family UPF0029
DRC71_RS11555	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DRC71_RS11575	COG2195	Cleaves the N-terminal amino acid of tripeptides
DRC71_RS11580	COG1929	Belongs to the glycerate kinase type-1 family
DRC71_RS11585	COG3118	belongs to the thioredoxin family
DRC71_RS11600	COG0812	UDP-N-acetylmuramate dehydrogenase activity
DRC71_RS11610	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DRC71_RS11615	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DRC71_RS11650	COG3104	oligopeptide transport
DRC71_RS11655	COG3104	oligopeptide transport
DRC71_RS11675	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
DRC71_RS11680	COG1174	glycine betaine transport
DRC71_RS11685	COG1125	glycine betaine transport
DRC71_RS11685	COG0517	IMP dehydrogenase activity
DRC71_RS11690	COG0514	ATP-dependent DNA helicase (RecQ)
DRC71_RS11705	COG2274	protein secretion by the type I secretion system
DRC71_RS11720	COG0463	Glycosyl transferase, family 2
DRC71_RS11725	COG1368	sulfuric ester hydrolase activity
DRC71_RS11735	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
DRC71_RS11755	COG0512	Glutamine amidotransferase of anthranilate synthase
DRC71_RS11765	COG0720	synthase
DRC71_RS11770	COG0602	queuosine metabolic process
DRC71_RS11785	COG0463	Glycosyl transferase, family 2
DRC71_RS11790	COG1253	flavin adenine dinucleotide binding
DRC71_RS11795	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DRC71_RS11795	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DRC71_RS11795	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DRC71_RS11800	COG1105	Belongs to the carbohydrate kinase PfkB family
DRC71_RS11805	COG1349	DNA-binding transcription factor activity
DRC71_RS11820	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
DRC71_RS11825	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
DRC71_RS11845	COG0039	L-malate dehydrogenase activity
DRC71_RS11860	COG4989	oxidoreductase activity
DRC71_RS11865	COG0523	cobalamin synthesis protein
DRC71_RS11875	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
DRC71_RS11880	COG4988	ABC transporter
DRC71_RS11885	COG1968	undecaprenyl-diphosphatase activity
DRC71_RS11895	COG1671	Belongs to the UPF0178 family
DRC71_RS11900	COG1611	Belongs to the LOG family
DRC71_RS11930	COG2839	Protein conserved in bacteria
DRC71_RS11935	COG2814	Major facilitator Superfamily
DRC71_RS11940	COG0583	DNA-binding transcription factor activity
DRC71_RS11955	COG0217	transcriptional regulatory protein
DRC71_RS11960	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
DRC71_RS11965	COG2022	thiamine diphosphate biosynthetic process
DRC71_RS11975	COG0352	thiamine-phosphate diphosphorylase activity
DRC71_RS11985	COG1388	LysM domain
DRC71_RS11985	COG3942	CHAP domain
DRC71_RS11990	COG0306	phosphate transporter
DRC71_RS11995	COG1392	Phosphate transport regulator
DRC71_RS12000	COG0577	efflux transmembrane transporter activity
DRC71_RS12005	COG1136	(ABC) transporter
DRC71_RS12015	COG0745	RESPONSE REGULATOR receiver
DRC71_RS12020	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DRC71_RS12025	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DRC71_RS12035	COG3949	Membrane
DRC71_RS12040	COG0477	Major facilitator Superfamily
DRC71_RS12050	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DRC71_RS12055	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DRC71_RS12060	COG1120	ATPase activity
DRC71_RS12065	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DRC71_RS12070	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
DRC71_RS12090	COG1132	(ABC) transporter
DRC71_RS12095	COG1686	Belongs to the peptidase S11 family
DRC71_RS12115	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
DRC71_RS12120	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
DRC71_RS12125	COG1682	transport, permease protein
DRC71_RS12135	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
DRC71_RS12140	COG0110	maltose O-acetyltransferase activity
DRC71_RS12150	COG1475	DNA binding
DRC71_RS12155	COG0019	diaminopimelate decarboxylase activity
DRC71_RS12165	COG4264	IucA IucC family
DRC71_RS12170	COG4264	IucA IucC family
DRC71_RS12175	COG2814	Major facilitator Superfamily
DRC71_RS12180	COG4264	IucA IucC family
DRC71_RS12185	COG2423	ornithine cyclodeaminase activity
DRC71_RS12195	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
DRC71_RS12200	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DRC71_RS12205	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DRC71_RS12215	COG1121	(ABC) transporter
DRC71_RS12220	COG1108	ABC-type Mn2 Zn2 transport systems permease components
DRC71_RS12225	COG0803	Belongs to the bacterial solute-binding protein 9 family
DRC71_RS12230	COG1320	monovalent cation:proton antiporter activity
DRC71_RS12235	COG2212	antiporter activity
DRC71_RS12240	COG1863	multisubunit Na H antiporter MnhE subunit
DRC71_RS12250	COG1006	Multisubunit Na H antiporter MnhC subunit
DRC71_RS12255	COG2111	Na H antiporter
DRC71_RS12260	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
DRC71_RS12260	COG2111	Na H antiporter
DRC71_RS12310	COG0546	phosphoglycolate phosphatase activity
DRC71_RS12315	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DRC71_RS12320	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
DRC71_RS12325	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
DRC71_RS12330	COG0805	protein transport
DRC71_RS12335	COG0018	arginyl-trna synthetase
DRC71_RS12350	COG1078	dGTPase activity
DRC71_RS12360	COG4844	belongs to the
DRC71_RS12435	COG0860	N-Acetylmuramoyl-L-alanine amidase
DRC71_RS12435	COG1388	LysM domain
DRC71_RS12475	COG5434	Belongs to the glycosyl hydrolase 28 family
DRC71_RS12555	COG1783	phage Terminase large subunit
DRC71_RS12660	COG0305	Participates in initiation and elongation during chromosome replication
DRC71_RS12735	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
DRC71_RS12750	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
DRC71_RS12785	COG0280	phosphate acetyltransferase
DRC71_RS12790	COG0095	Lipoate-protein ligase
DRC71_RS12795	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DRC71_RS12800	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
DRC71_RS12810	COG2814	Major facilitator Superfamily
DRC71_RS12815	COG1566	PFAM secretion protein HlyD family protein
DRC71_RS12825	COG2311	Membrane
DRC71_RS12860	COG2363	Small membrane protein
DRC71_RS12890	COG0183	Belongs to the thiolase family
DRC71_RS12895	COG0318	PFAM AMP-dependent synthetase and ligase
DRC71_RS12900	COG0588	phosphoglycerate mutase activity
DRC71_RS12905	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
DRC71_RS12910	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
DRC71_RS12920	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
DRC71_RS12935	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DRC71_RS12935	COG2190	(PTS) system
DRC71_RS12935	COG1263	PTS System
DRC71_RS12950	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
DRC71_RS12955	COG1469	GTP cyclohydrolase I activity
DRC71_RS13005	COG0577	efflux transmembrane transporter activity
DRC71_RS13005	COG1136	(ABC) transporter
DRC71_RS13020	COG0561	phosphatase activity
DRC71_RS13030	COG1428	Deoxynucleoside kinase
DRC71_RS13035	COG1428	Deoxynucleoside kinase
DRC71_RS13040	COG0546	phosphoglycolate phosphatase activity
DRC71_RS13070	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DRC71_RS13080	COG1473	amidohydrolase
DRC71_RS13085	COG3527	Alpha-acetolactate decarboxylase
DRC71_RS13090	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
DRC71_RS13095	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
DRC71_RS13100	COG0049	tRNA binding
DRC71_RS13105	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
DRC71_RS13115	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
DRC71_RS13120	COG0085	RNA polymerase activity
DRC71_RS13125	COG2813	Specifically methylates the guanine in position
DRC71_RS13135	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
DRC71_RS13140	COG0081	regulation of translation
DRC71_RS13145	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
DRC71_RS13150	COG0250	Participates in transcription elongation, termination and antitermination
DRC71_RS13155	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
DRC71_RS13160	COG0267	Belongs to the bacterial ribosomal protein bL33 family
DRC71_RS13180	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
DRC71_RS13185	COG0215	cysteine-tRNA ligase activity
DRC71_RS13190	COG1045	serine acetyltransferase
DRC71_RS13195	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DRC71_RS13205	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
DRC71_RS13210	COG4956	integral membrane protein (PIN domain superfamily)
DRC71_RS13215	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
DRC71_RS13255	COG3869	Catalyzes the specific phosphorylation of arginine residues in
DRC71_RS13260	COG3880	PFAM UvrB UvrC protein
DRC71_RS13270	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
DRC71_RS13280	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
DRC71_RS13285	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
DRC71_RS13290	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DRC71_RS13295	COG1289	transmembrane transporter activity
DRC71_RS13385	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
DRC71_RS13390	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
DRC71_RS13400	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
DRC71_RS13410	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
DRC71_RS13415	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DRC71_RS13430	COG1098	S1 RNA binding domain
DRC71_RS13440	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
DRC71_RS13445	COG3956	TIGRFAM MazG family protein
DRC71_RS13450	COG2244	polysaccharide biosynthetic process
DRC71_RS13455	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
DRC71_RS13460	COG0193	aminoacyl-tRNA hydrolase activity
DRC71_RS13470	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
DRC71_RS13475	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
DRC71_RS13480	COG2088	sporulation resulting in formation of a cellular spore
DRC71_RS13485	COG0251	oxidation-reduction process
DRC71_RS13490	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
DRC71_RS13495	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
DRC71_RS13500	COG4466	Protein conserved in bacteria
DRC71_RS13510	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
DRC71_RS13515	COG0084	hydrolase, TatD family'