locus-tag	class	description
JMB28_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
JMB28_RS00010	COG0592	DNA-directed DNA polymerase activity
JMB28_RS00015	COG2501	S4 domain
JMB28_RS00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
JMB28_RS00035	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
JMB28_RS00040	COG2986	histidine ammonia-lyase
JMB28_RS00045	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
JMB28_RS00050	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
JMB28_RS00060	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
JMB28_RS00070	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
JMB28_RS00075	COG0359	binds to the 23S rRNA
JMB28_RS00080	COG0305	Participates in initiation and elongation during chromosome replication
JMB28_RS00085	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
JMB28_RS00090	COG1819	glycosyl
JMB28_RS00110	COG0477	Major facilitator Superfamily
JMB28_RS00115	COG0745	RESPONSE REGULATOR receiver
JMB28_RS00120	COG5002	protein histidine kinase activity
JMB28_RS00135	COG2211	Major facilitator Superfamily
JMB28_RS00145	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
JMB28_RS00150	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
JMB28_RS00180	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
JMB28_RS00230	COG0640	Transcriptional regulator
JMB28_RS00235	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
JMB28_RS00240	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
JMB28_RS00255	COG0640	Transcriptional regulator
JMB28_RS00275	COG2003	Belongs to the UPF0758 family
JMB28_RS00295	COG2217	Heavy metal translocating P-type atpase
JMB28_RS00300	COG1388	LysM domain
JMB28_RS00305	COG0300	oxidoreductase activity
JMB28_RS00310	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
JMB28_RS00355	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JMB28_RS00360	COG1120	ATPase activity
JMB28_RS00380	COG1349	DNA-binding transcription factor activity
JMB28_RS00385	COG3842	ATPase activity
JMB28_RS00420	COG1228	amidohydrolase
JMB28_RS00445	COG1846	Transcriptional regulator
JMB28_RS00460	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
JMB28_RS00465	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JMB28_RS00465	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JMB28_RS00470	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JMB28_RS00475	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JMB28_RS00485	COG3711	transcriptional antiterminator
JMB28_RS00490	COG1414	Transcriptional regulator
JMB28_RS00495	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JMB28_RS00510	COG2610	gluconate transmembrane transporter activity
JMB28_RS00515	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
JMB28_RS00520	COG1335	isochorismatase
JMB28_RS00525	COG1522	sequence-specific DNA binding
JMB28_RS00530	COG1733	regulation of RNA biosynthetic process
JMB28_RS00535	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JMB28_RS00540	COG2210	Belongs to the sulfur carrier protein TusA family
JMB28_RS00545	COG1937	Protein conserved in bacteria
JMB28_RS00550	COG0730	response to heat
JMB28_RS00560	COG1349	DNA-binding transcription factor activity
JMB28_RS00565	COG1012	belongs to the aldehyde dehydrogenase family
JMB28_RS00570	COG3718	enzyme involved in inositol metabolism
JMB28_RS00575	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JMB28_RS00580	COG3962	Belongs to the TPP enzyme family
JMB28_RS00585	COG0673	inositol 2-dehydrogenase activity
JMB28_RS00590	COG1082	Xylose isomerase domain protein TIM barrel
JMB28_RS00595	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
JMB28_RS00600	COG0673	inositol 2-dehydrogenase activity
JMB28_RS00605	COG0191	fructose-bisphosphate aldolase activity
JMB28_RS00610	COG1942	4-Oxalocrotonate Tautomerase
JMB28_RS00620	COG4221	oxidoreductase activity
JMB28_RS00635	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
JMB28_RS00650	COG1349	DNA-binding transcription factor activity
JMB28_RS00655	COG1070	Carbohydrate kinase
JMB28_RS00660	COG4806	L-rhamnose isomerase
JMB28_RS00665	COG0235	Class ii aldolase
JMB28_RS00670	COG3254	rhamnose metabolic process
JMB28_RS00675	COG2814	Major facilitator Superfamily
JMB28_RS00680	COG1012	belongs to the aldehyde dehydrogenase family
JMB28_RS00700	COG4145	pantothenate transmembrane transporter activity
JMB28_RS00710	COG1733	regulation of RNA biosynthetic process
JMB28_RS00715	COG1902	pentaerythritol trinitrate reductase activity
JMB28_RS00720	COG0583	DNA-binding transcription factor activity
JMB28_RS00730	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
JMB28_RS00755	COG0601	transmembrane transport
JMB28_RS00760	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JMB28_RS00765	COG0444	Belongs to the ABC transporter superfamily
JMB28_RS00770	COG1124	(ABC) transporter
JMB28_RS00805	COG0702	epimerase
JMB28_RS00810	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
JMB28_RS00840	COG3871	stress protein (general stress protein 26)
JMB28_RS00845	COG0415	Belongs to the DNA photolyase family
JMB28_RS00870	COG0583	DNA-binding transcription factor activity
JMB28_RS00875	COG2207	Transcriptional regulator
JMB28_RS00880	COG2211	Major facilitator Superfamily
JMB28_RS00885	COG3250	beta-galactosidase activity
JMB28_RS00895	COG4555	ABC transporter
JMB28_RS00905	COG1476	TRANSCRIPTIONal
JMB28_RS00910	COG2814	Major facilitator Superfamily
JMB28_RS00915	COG2814	Major facilitator Superfamily
JMB28_RS00940	COG2814	Major facilitator Superfamily
JMB28_RS00945	COG0463	Glycosyl transferase, family 2
JMB28_RS00965	COG1695	Transcriptional regulator
JMB28_RS00970	COG1028	Short-chain dehydrogenase reductase Sdr
JMB28_RS00975	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
JMB28_RS00980	COG1063	alcohol dehydrogenase
JMB28_RS00990	COG1063	alcohol dehydrogenase
JMB28_RS00995	COG3775	system Galactitol-specific IIC component
JMB28_RS01000	COG3414	Phosphotransferase system galactitol-specific IIB component
JMB28_RS01025	COG3192	ethanolamine utilization protein
JMB28_RS01030	COG1028	Short-chain dehydrogenase reductase Sdr
JMB28_RS01040	COG1012	belongs to the aldehyde dehydrogenase family
JMB28_RS01055	COG2318	DinB family
JMB28_RS01080	COG1388	LysM domain
JMB28_RS01085	COG1388	LysM domain
JMB28_RS01090	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
JMB28_RS01095	COG1054	Belongs to the UPF0176 family
JMB28_RS01110	COG1609	Transcriptional regulator
JMB28_RS01125	COG2160	L-arabinose isomerase activity
JMB28_RS01155	COG1695	Transcriptional regulator
JMB28_RS01160	COG3479	Phenolic acid decarboxylase
JMB28_RS01180	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JMB28_RS01185	COG2188	Transcriptional regulator
JMB28_RS01195	COG2814	Major facilitator Superfamily
JMB28_RS01195	COG0477	Major facilitator Superfamily
JMB28_RS01200	COG1070	Carbohydrate kinase
JMB28_RS01205	COG2115	Belongs to the xylose isomerase family
JMB28_RS01210	COG1846	Transcriptional regulator
JMB28_RS01210	COG1940	carbohydrate kinase activity
JMB28_RS01215	COG1511	domain protein
JMB28_RS01245	COG1070	Carbohydrate kinase
JMB28_RS01250	COG0352	thiamine-phosphate diphosphorylase activity
JMB28_RS01255	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
JMB28_RS01265	COG2022	thiamine diphosphate biosynthetic process
JMB28_RS01270	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
JMB28_RS01275	COG1328	CTP reductase activity
JMB28_RS01280	COG0602	queuosine metabolic process
JMB28_RS01285	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
JMB28_RS01295	COG0431	NADPH-dependent FMN reductase
JMB28_RS01305	COG0346	lactoylglutathione lyase activity
JMB28_RS01310	COG2188	Transcriptional regulator
JMB28_RS01315	COG2084	Dehydrogenase
JMB28_RS01350	COG1115	amino acid carrier protein
JMB28_RS01370	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
JMB28_RS01375	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
JMB28_RS01380	COG0579	oxidoreductase
JMB28_RS01435	COG0477	Major facilitator Superfamily
JMB28_RS01440	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
JMB28_RS01445	COG2814	Major facilitator Superfamily
JMB28_RS01465	COG0584	glycerophosphoryl diester phosphodiesterase
JMB28_RS01475	COG0668	transmembrane transport
JMB28_RS01480	COG1846	Transcriptional regulator
JMB28_RS01485	COG3961	Belongs to the TPP enzyme family
JMB28_RS01495	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JMB28_RS01535	COG0673	inositol 2-dehydrogenase activity
JMB28_RS01540	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
JMB28_RS01545	COG1691	(AIR) carboxylase
JMB28_RS01550	COG1606	tRNA processing
JMB28_RS01555	COG3875	lactate racemase activity
JMB28_RS01565	COG1929	Belongs to the glycerate kinase type-1 family
JMB28_RS01570	COG3835	regulator
JMB28_RS01580	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
JMB28_RS01595	COG0574	Belongs to the PEP-utilizing enzyme family
JMB28_RS01595	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
JMB28_RS01600	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
JMB28_RS01625	COG1476	TRANSCRIPTIONal
JMB28_RS01630	COG2807	transmembrane transport
JMB28_RS01640	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JMB28_RS01645	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
JMB28_RS01650	COG1012	belongs to the aldehyde dehydrogenase family
JMB28_RS01670	COG2226	methyltransferase
JMB28_RS01675	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
JMB28_RS01680	COG1510	regulation of RNA biosynthetic process
JMB28_RS01685	COG1012	belongs to the aldehyde dehydrogenase family
JMB28_RS01690	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
JMB28_RS01695	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
JMB28_RS01695	COG0463	Glycosyl transferase, family 2
JMB28_RS01705	COG0778	Nitroreductase
JMB28_RS01710	COG2843	Capsule synthesis protein
JMB28_RS01720	COG0477	Major facilitator Superfamily
JMB28_RS01725	COG0531	amino acid
JMB28_RS01730	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
JMB28_RS01735	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
JMB28_RS01740	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
JMB28_RS01745	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
JMB28_RS01750	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
JMB28_RS01760	COG0431	NADPH-dependent FMN reductase
JMB28_RS01775	COG1620	l-lactate permease
JMB28_RS01780	COG2814	Major facilitator Superfamily
JMB28_RS01785	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
JMB28_RS01790	COG1263	PTS System
JMB28_RS01790	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JMB28_RS01790	COG2190	(PTS) system
JMB28_RS01795	COG0363	glucosamine-6-phosphate deaminase activity
JMB28_RS01805	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
JMB28_RS01810	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
JMB28_RS01820	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
JMB28_RS01830	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JMB28_RS01835	COG0765	amino acid transport
JMB28_RS01840	COG1126	abc transporter atp-binding protein
JMB28_RS01845	COG3711	transcriptional antiterminator
JMB28_RS01850	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JMB28_RS01860	COG3037	sugar-specific permease SgaT UlaA
JMB28_RS01865	COG4297	protein containing double-stranded beta helix domain
JMB28_RS01875	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
JMB28_RS01885	COG1464	Belongs to the NlpA lipoprotein family
JMB28_RS01890	COG0039	L-malate dehydrogenase activity
JMB28_RS01895	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JMB28_RS01895	COG3711	transcriptional antiterminator
JMB28_RS01900	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JMB28_RS01900	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JMB28_RS01900	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JMB28_RS01905	COG1482	cell wall glycoprotein biosynthetic process
JMB28_RS01910	COG1940	carbohydrate kinase activity
JMB28_RS01920	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
JMB28_RS01925	COG0626	cystathionine gamma-synthase activity
JMB28_RS01930	COG2271	Major facilitator Superfamily
JMB28_RS01950	COG0829	nickel cation binding
JMB28_RS01955	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
JMB28_RS01960	COG0830	nickel cation binding
JMB28_RS01965	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
JMB28_RS01970	COG0804	urea catabolic process
JMB28_RS01975	COG0832	Belongs to the urease beta subunit family
JMB28_RS01980	COG0831	urea catabolic process
JMB28_RS01985	COG4413	Urea transporter
JMB28_RS01990	COG0747	negative chemotaxis
JMB28_RS02015	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
JMB28_RS02025	COG0531	amino acid
JMB28_RS02030	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JMB28_RS02040	COG0561	phosphatase activity
JMB28_RS02050	COG0167	dihydroorotate dehydrogenase activity
JMB28_RS02080	COG0697	spore germination
JMB28_RS02085	COG1113	amino acid transport
JMB28_RS02115	COG0741	lytic transglycosylase activity
JMB28_RS02120	COG0436	Aminotransferase
JMB28_RS02130	COG2608	mercury ion transmembrane transporter activity
JMB28_RS02135	COG2217	Heavy metal translocating P-type atpase
JMB28_RS02140	COG0659	secondary active sulfate transmembrane transporter activity
JMB28_RS02145	COG1136	(ABC) transporter
JMB28_RS02150	COG0577	efflux transmembrane transporter activity
JMB28_RS02155	COG1028	Short-chain dehydrogenase reductase Sdr
JMB28_RS02165	COG0471	metal ion transport
JMB28_RS02170	COG5505	Protein of unknown function (DUF819)
JMB28_RS02185	COG4336	lyase activity
JMB28_RS02195	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
JMB28_RS02200	COG1012	belongs to the aldehyde dehydrogenase family
JMB28_RS02210	COG2409	Drug exporters of the RND superfamily
JMB28_RS02225	COG1473	amidohydrolase
JMB28_RS02250	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
JMB28_RS02255	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
JMB28_RS02275	COG3425	synthase
JMB28_RS02290	COG3386	PFAM SMP-30 Gluconolaconase
JMB28_RS02295	COG3942	CHAP domain
JMB28_RS02300	COG1757	Na H antiporter
JMB28_RS02305	COG0583	DNA-binding transcription factor activity
JMB28_RS02310	COG1380	Effector of murein hydrolase LrgA
JMB28_RS02320	COG0028	Belongs to the TPP enzyme family
JMB28_RS02325	COG1288	antiporter activity
JMB28_RS02330	COG2190	(PTS) system
JMB28_RS02330	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JMB28_RS02330	COG1263	PTS System
JMB28_RS02345	COG2515	1-aminocyclopropane-1-carboxylate deaminase
JMB28_RS02365	COG0657	acetylesterase activity
JMB28_RS02370	COG0697	spore germination
JMB28_RS02375	COG1917	Cupin 2, conserved barrel domain protein
JMB28_RS02375	COG2207	Transcriptional regulator
JMB28_RS02380	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
JMB28_RS02390	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
JMB28_RS02400	COG2843	Capsule synthesis protein
JMB28_RS02420	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
JMB28_RS02425	COG1063	alcohol dehydrogenase
JMB28_RS02430	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
JMB28_RS02450	COG1129	ABC transporter
JMB28_RS02470	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
JMB28_RS02480	COG3764	Sortase (surface protein transpeptidase)
JMB28_RS02485	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
JMB28_RS02490	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
JMB28_RS02500	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
JMB28_RS02505	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
JMB28_RS02520	COG2249	NAD(P)H dehydrogenase (quinone) activity
JMB28_RS02525	COG0561	phosphatase activity
JMB28_RS02530	COG0778	Nitroreductase
JMB28_RS02535	COG2514	catechol 2,3-dioxygenase activity
JMB28_RS02545	COG1132	(ABC) transporter
JMB28_RS02550	COG1132	(ABC) transporter
JMB28_RS02560	COG0803	Belongs to the bacterial solute-binding protein 9 family
JMB28_RS02565	COG1012	belongs to the aldehyde dehydrogenase family
JMB28_RS02570	COG1846	Transcriptional regulator
JMB28_RS02575	COG0346	lactoylglutathione lyase activity
JMB28_RS02580	COG0346	lactoylglutathione lyase activity
JMB28_RS02585	COG0400	carboxylic ester hydrolase activity
JMB28_RS02590	COG0471	metal ion transport
JMB28_RS02595	COG3949	Membrane
JMB28_RS02605	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
JMB28_RS02610	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
JMB28_RS02615	COG0586	Pfam SNARE associated Golgi protein
JMB28_RS02620	COG2271	Major facilitator Superfamily
JMB28_RS02630	COG3527	Alpha-acetolactate decarboxylase
JMB28_RS02635	COG1289	transmembrane transporter activity
JMB28_RS02650	COG4876	unkown
JMB28_RS02655	COG2357	RelA SpoT domain protein
JMB28_RS02665	COG1802	Transcriptional regulator
JMB28_RS02670	COG1070	Carbohydrate kinase
JMB28_RS02675	COG2610	gluconate transmembrane transporter activity
JMB28_RS02685	COG3949	Membrane
JMB28_RS02695	COG2211	Major facilitator Superfamily
JMB28_RS02700	COG3250	beta-galactosidase activity
JMB28_RS02715	COG0800	Aldolase
JMB28_RS02720	COG2211	Major facilitator Superfamily
JMB28_RS02725	COG1904	glucuronate isomerase
JMB28_RS02730	COG1312	Catalyzes the dehydration of D-mannonate
JMB28_RS02745	COG4221	oxidoreductase activity
JMB28_RS02775	COG0107	imidazoleglycerol-phosphate synthase activity
JMB28_RS02780	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
JMB28_RS02785	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
JMB28_RS02790	COG0131	Imidazoleglycerol-phosphate dehydratase
JMB28_RS02795	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
JMB28_RS02800	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
JMB28_RS02805	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
JMB28_RS02815	COG3048	D-serine ammonia-lyase activity
JMB28_RS02820	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
JMB28_RS02825	COG0248	Ppx GppA phosphatase
JMB28_RS02830	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
JMB28_RS02835	COG1028	Short-chain dehydrogenase reductase Sdr
JMB28_RS02840	COG1363	Peptidase, m42
JMB28_RS02850	COG0069	glutamate synthase activity
JMB28_RS02860	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
JMB28_RS02865	COG0390	transport system, permease component
JMB28_RS02870	COG2814	Major facilitator Superfamily
JMB28_RS02875	COG2851	Citrate transporter
JMB28_RS02880	COG0531	amino acid
JMB28_RS02885	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
JMB28_RS02890	COG1309	transcriptional regulator
JMB28_RS02895	COG3246	L-lysine catabolic process to acetate
JMB28_RS02900	COG1250	3-hydroxyacyl-CoA dehydrogenase
JMB28_RS02915	COG1174	glycine betaine transport
JMB28_RS02925	COG1174	glycine betaine transport
JMB28_RS02935	COG1346	cytolysis
JMB28_RS02940	COG1380	Effector of murein hydrolase LrgA
JMB28_RS02945	COG3279	Response regulator of the LytR AlgR family
JMB28_RS02950	COG3275	phosphorelay sensor kinase activity
JMB28_RS02960	COG4187	Peptidase family M20/M25/M40
JMB28_RS02980	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
JMB28_RS02990	COG0706	membrane insertase activity
JMB28_RS02995	COG0025	NhaP-type Na H and K H
JMB28_RS03015	COG2814	Major facilitator Superfamily
JMB28_RS03025	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
JMB28_RS03030	COG1388	LysM domain
JMB28_RS03035	COG0588	phosphoglycerate mutase activity
JMB28_RS03045	COG2814	Major facilitator Superfamily
JMB28_RS03055	COG2348	transferase activity, transferring amino-acyl groups
JMB28_RS03070	COG3443	Belongs to the bacterial solute-binding protein 9 family
JMB28_RS03070	COG0803	Belongs to the bacterial solute-binding protein 9 family
JMB28_RS03075	COG2353	YceI-like domain
JMB28_RS03085	COG1695	Transcriptional regulator
JMB28_RS03105	COG2723	6-phospho-beta-galactosidase activity
JMB28_RS03110	COG1263	PTS System
JMB28_RS03110	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JMB28_RS03110	COG2190	(PTS) system
JMB28_RS03115	COG2188	Transcriptional regulator
JMB28_RS03120	COG1959	2 iron, 2 sulfur cluster binding
JMB28_RS03125	COG2116	formate transmembrane transporter activity
JMB28_RS03130	COG0454	-acetyltransferase
JMB28_RS03145	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
JMB28_RS03150	COG2146	nitrite reductase [NAD(P)H] activity
JMB28_RS03165	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
JMB28_RS03170	COG1140	nitrate reductase beta subunit
JMB28_RS03180	COG2181	nitrate reductase activity
JMB28_RS03190	COG4585	Histidine kinase
JMB28_RS03200	COG2223	nitrite transmembrane transporter activity
JMB28_RS03205	COG0071	Belongs to the small heat shock protein (HSP20) family
JMB28_RS03215	COG1846	Transcriptional regulator
JMB28_RS03240	COG1263	PTS System
JMB28_RS03240	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JMB28_RS03260	COG1283	sodium-dependent phosphate transmembrane transporter activity
JMB28_RS03265	COG1028	Short-chain dehydrogenase reductase Sdr
JMB28_RS03270	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JMB28_RS03275	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JMB28_RS03280	COG1288	antiporter activity
JMB28_RS03285	COG1349	DNA-binding transcription factor activity
JMB28_RS03290	COG1063	alcohol dehydrogenase
JMB28_RS03295	COG2376	Dihydroxyacetone kinase
JMB28_RS03305	COG0698	ribose 5-phosphate isomerase
JMB28_RS03315	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
JMB28_RS03320	COG0492	ferredoxin-NADP+ reductase activity
JMB28_RS03325	COG0456	acetyltransferase
JMB28_RS03330	COG2814	Major facilitator Superfamily
JMB28_RS03335	COG0604	alcohol dehydrogenase
JMB28_RS03355	COG1620	l-lactate permease
JMB28_RS03360	COG0438	transferase activity, transferring glycosyl groups
JMB28_RS03370	COG5002	protein histidine kinase activity
JMB28_RS03370	COG3850	Histidine kinase
JMB28_RS03375	COG0745	RESPONSE REGULATOR receiver
JMB28_RS03380	COG0577	efflux transmembrane transporter activity
JMB28_RS03385	COG1136	(ABC) transporter
JMB28_RS03400	COG4640	response to antibiotic
JMB28_RS03405	COG2814	Major facilitator Superfamily
JMB28_RS03415	COG1566	PFAM secretion protein HlyD family protein
JMB28_RS03420	COG2814	Major facilitator Superfamily
JMB28_RS03445	COG0598	Magnesium transport protein CorA
JMB28_RS03450	COG1304	FMN binding
JMB28_RS03455	COG0786	glutamate:sodium symporter activity
JMB28_RS03460	COG1695	Transcriptional regulator
JMB28_RS03475	COG1757	Na H antiporter
JMB28_RS03480	COG2094	Belongs to the DNA glycosylase MPG family
JMB28_RS03485	COG3152	Membrane
JMB28_RS03490	COG1069	ribulokinase activity
JMB28_RS03495	COG4152	abc transporter atp-binding protein
JMB28_RS03500	COG1668	transmembrane transport
JMB28_RS03505	COG2017	converts alpha-aldose to the beta-anomer
JMB28_RS03510	COG2258	MOSC domain
JMB28_RS03515	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
JMB28_RS03520	COG1266	CAAX protease self-immunity
JMB28_RS03525	COG0010	Belongs to the arginase family
JMB28_RS03530	COG0583	DNA-binding transcription factor activity
JMB28_RS03535	COG3314	Sporulation integral membrane protein YlbJ
JMB28_RS03540	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
JMB28_RS03545	COG1228	amidohydrolase
JMB28_RS03550	COG0659	secondary active sulfate transmembrane transporter activity
JMB28_RS03555	COG1473	amidohydrolase
JMB28_RS03560	COG1028	Short-chain dehydrogenase reductase Sdr
JMB28_RS03565	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
JMB28_RS03585	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JMB28_RS03585	COG1263	PTS System
JMB28_RS03595	COG0385	Bile acid
JMB28_RS03600	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
JMB28_RS03625	COG1113	amino acid transport
JMB28_RS03630	COG1785	Belongs to the alkaline phosphatase family
JMB28_RS03640	COG1263	PTS System
JMB28_RS03640	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JMB28_RS03645	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
JMB28_RS03665	COG0483	inositol monophosphate 1-phosphatase activity
JMB28_RS03670	COG1316	TRANSCRIPTIONal
JMB28_RS03675	COG3383	formate dehydrogenase (NAD+) activity
JMB28_RS03690	COG4193	domain, Protein
JMB28_RS03700	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
JMB28_RS03705	COG2076	Multidrug Resistance protein
JMB28_RS03710	COG2076	Multidrug Resistance protein
JMB28_RS03715	COG3942	CHAP domain
JMB28_RS03730	COG1757	Na H antiporter
JMB28_RS03735	COG3942	CHAP domain
JMB28_RS03760	COG0765	amino acid transport
JMB28_RS03765	COG0765	amino acid transport
JMB28_RS03770	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JMB28_RS03775	COG1126	abc transporter atp-binding protein
JMB28_RS03780	COG1960	acyl-CoA dehydrogenase activity
JMB28_RS03785	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
JMB28_RS03790	COG1268	BioY protein
JMB28_RS03800	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
JMB28_RS03805	COG1609	Transcriptional regulator
JMB28_RS03810	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
JMB28_RS03815	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
JMB28_RS03820	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
JMB28_RS03825	COG0725	ABC transporter, periplasmic molybdate-binding protein
JMB28_RS03830	COG4149	molybdate abc transporter
JMB28_RS03835	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
JMB28_RS03845	COG1510	regulation of RNA biosynthetic process
JMB28_RS03850	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
JMB28_RS03855	COG0521	Mo-molybdopterin cofactor biosynthetic process
JMB28_RS03860	COG0315	cyclic pyranopterin monophosphate synthase activity
JMB28_RS03870	COG1763	Mo-molybdopterin cofactor biosynthetic process
JMB28_RS03885	COG0746	molybdenum cofactor guanylyltransferase activity
JMB28_RS03890	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
JMB28_RS03915	COG2348	transferase activity, transferring amino-acyl groups
JMB28_RS03920	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
JMB28_RS03945	COG4975	Glucose uptake
JMB28_RS03955	COG0551	DNA topoisomerase type I activity
JMB28_RS03955	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
JMB28_RS03960	COG2252	PERMEase
JMB28_RS03970	COG0051	transcription antitermination factor activity, RNA binding
JMB28_RS03975	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
JMB28_RS03980	COG0088	Forms part of the polypeptide exit tunnel
JMB28_RS03985	COG0089	rRNA binding
JMB28_RS03990	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
JMB28_RS03995	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
JMB28_RS04000	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
JMB28_RS04005	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
JMB28_RS04010	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
JMB28_RS04015	COG0255	Belongs to the universal ribosomal protein uL29 family
JMB28_RS04020	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
JMB28_RS04025	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
JMB28_RS04030	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
JMB28_RS04035	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
JMB28_RS04040	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
JMB28_RS04045	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
JMB28_RS04050	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
JMB28_RS04055	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
JMB28_RS04060	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
JMB28_RS04065	COG1841	ribosomal large subunit assembly
JMB28_RS04070	COG0200	Binds to the 23S rRNA
JMB28_RS04075	COG0201	protein transport
JMB28_RS04080	COG0563	adenylate kinase activity
JMB28_RS04090	COG0257	Belongs to the bacterial ribosomal protein bL36 family
JMB28_RS04095	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
JMB28_RS04100	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
JMB28_RS04105	COG0202	RNA polymerase activity
JMB28_RS04110	COG0203	ribosomal protein L17
JMB28_RS04115	COG1122	ATPase activity
JMB28_RS04120	COG1122	ATPase activity
JMB28_RS04130	COG0101	tRNA pseudouridine synthase activity
JMB28_RS04135	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
JMB28_RS04140	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
JMB28_RS04150	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JMB28_RS04155	COG2130	NADP-dependent
JMB28_RS04160	COG0604	alcohol dehydrogenase
JMB28_RS04165	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
JMB28_RS04180	COG1302	Protein conserved in bacteria
JMB28_RS04185	COG4264	IucA IucC family
JMB28_RS04190	COG2814	Major facilitator Superfamily
JMB28_RS04195	COG4264	IucA IucC family
JMB28_RS04200	COG3457	Alanine racemase
JMB28_RS04205	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
JMB28_RS04210	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JMB28_RS04215	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JMB28_RS04220	COG3314	Sporulation integral membrane protein YlbJ
JMB28_RS04225	COG2329	Antibiotic biosynthesis monooxygenase
JMB28_RS04235	COG1988	membrane-bound metal-dependent
JMB28_RS04240	COG4284	Utp--glucose-1-phosphate uridylyltransferase
JMB28_RS04245	COG1272	protein, Hemolysin III
JMB28_RS04260	COG0489	protein tyrosine kinase activity
JMB28_RS04315	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
JMB28_RS04325	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
JMB28_RS04330	COG0246	Mannitol dehydrogenase
JMB28_RS04340	COG3711	transcriptional antiterminator
JMB28_RS04345	COG2213	PTS system mannitol-specific
JMB28_RS04360	COG1119	ATPase activity
JMB28_RS04390	COG0640	Transcriptional regulator
JMB28_RS04395	COG0702	epimerase
JMB28_RS04400	COG2186	Transcriptional regulator
JMB28_RS04405	COG1482	cell wall glycoprotein biosynthetic process
JMB28_RS04415	COG2855	membrane
JMB28_RS04430	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JMB28_RS04435	COG0783	Belongs to the Dps family
JMB28_RS04440	COG0813	purine-nucleoside phosphorylase activity
JMB28_RS04445	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
JMB28_RS04450	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
JMB28_RS04455	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
JMB28_RS04465	COG1854	S-ribosylhomocysteine lyase activity
JMB28_RS04490	COG5146	pantothenate kinase activity
JMB28_RS04495	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JMB28_RS04505	COG0504	CTP synthase activity
JMB28_RS04510	COG0191	fructose-bisphosphate aldolase activity
JMB28_RS04515	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
JMB28_RS04525	COG1012	belongs to the aldehyde dehydrogenase family
JMB28_RS04530	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
JMB28_RS04535	COG0254	rRNA binding
JMB28_RS04540	COG1435	thymidine kinase activity
JMB28_RS04545	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
JMB28_RS04550	COG2890	protein-(glutamine-N5) methyltransferase activity
JMB28_RS04555	COG0009	L-threonylcarbamoyladenylate synthase
JMB28_RS04560	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
JMB28_RS04565	COG4475	Protein of unknown function (DUF436)
JMB28_RS04570	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
JMB28_RS04575	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
JMB28_RS04580	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
JMB28_RS04590	COG0356	it plays a direct role in the translocation of protons across the membrane
JMB28_RS04595	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
JMB28_RS04600	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
JMB28_RS04605	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
JMB28_RS04610	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
JMB28_RS04615	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
JMB28_RS04620	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
JMB28_RS04625	COG0355	proton-transporting ATP synthase activity, rotational mechanism
JMB28_RS04635	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
JMB28_RS04640	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
JMB28_RS04650	COG0629	single-stranded DNA binding
JMB28_RS04655	COG1388	LysM domain
JMB28_RS04660	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
JMB28_RS04670	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
JMB28_RS04675	COG0352	thiamine-phosphate diphosphorylase activity
JMB28_RS04680	COG0706	membrane insertase activity
JMB28_RS04685	COG1418	mRNA catabolic process
JMB28_RS04695	COG1937	Protein conserved in bacteria
JMB28_RS04710	COG0772	Belongs to the SEDS family
JMB28_RS04715	COG1181	Belongs to the D-alanine--D-alanine ligase family
JMB28_RS04720	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
JMB28_RS04725	COG0513	Belongs to the DEAD box helicase family
JMB28_RS04735	COG3428	Bacterial PH domain
JMB28_RS04745	COG0736	holo-[acyl-carrier-protein] synthase activity
JMB28_RS04750	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
JMB28_RS04760	COG2337	Toxic component of a toxin-antitoxin (TA) module
JMB28_RS04770	COG2208	phosphoserine phosphatase activity
JMB28_RS04785	COG1191	sigma factor activity
JMB28_RS04790	COG2183	response to ionizing radiation
JMB28_RS04795	COG3091	SprT-like family
JMB28_RS04825	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
JMB28_RS04830	COG0066	3-isopropylmalate dehydratase activity
JMB28_RS04835	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
JMB28_RS04840	COG0473	3-isopropylmalate dehydrogenase activity
JMB28_RS04845	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
JMB28_RS04850	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
JMB28_RS04855	COG0440	acetolactate synthase activity
JMB28_RS04860	COG0028	Belongs to the TPP enzyme family
JMB28_RS04865	COG0129	dihydroxy-acid dehydratase activity
JMB28_RS04870	COG0802	atpase or kinase
JMB28_RS04875	COG1214	PFAM Peptidase M22, glycoprotease
JMB28_RS04880	COG0456	acetyltransferase
JMB28_RS04885	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
JMB28_RS04895	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
JMB28_RS04900	COG0488	(ABC) transporter
JMB28_RS04905	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
JMB28_RS04910	COG2391	methyltransferase activity
JMB28_RS04915	COG0425	Belongs to the sulfur carrier protein TusA family
JMB28_RS04925	COG1609	Transcriptional regulator
JMB28_RS04930	COG1621	beta-fructofuranosidase activity
JMB28_RS04935	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JMB28_RS04940	COG3279	Response regulator of the LytR AlgR family
JMB28_RS04945	COG3290	protein histidine kinase activity
JMB28_RS04955	COG4512	PFAM Accessory gene regulator B
JMB28_RS04980	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
JMB28_RS04985	COG0459	protein refolding
JMB28_RS05005	COG1725	Transcriptional regulator
JMB28_RS05020	COG1131	(ABC) transporter
JMB28_RS05065	COG2706	6-phosphogluconolactonase activity
JMB28_RS05070	COG1012	belongs to the aldehyde dehydrogenase family
JMB28_RS05075	COG1227	inorganic diphosphatase activity
JMB28_RS05080	COG1335	isochorismatase
JMB28_RS05090	COG0471	metal ion transport
JMB28_RS05095	COG0077	Prephenate dehydratase
JMB28_RS05105	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
JMB28_RS05110	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
JMB28_RS05115	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
JMB28_RS05125	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
JMB28_RS05130	COG4496	protein, YerC YecD
JMB28_RS05135	COG1876	peptidase activity
JMB28_RS05140	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
JMB28_RS05150	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
JMB28_RS05155	COG4851	CamS sex pheromone cAM373 precursor
JMB28_RS05160	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
JMB28_RS05165	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
JMB28_RS05170	COG0154	amidase activity
JMB28_RS05175	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
JMB28_RS05180	COG1597	lipid kinase activity
JMB28_RS05185	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
JMB28_RS05195	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
JMB28_RS05205	COG1528	Iron-storage protein
JMB28_RS05220	COG4129	membrane
JMB28_RS05225	COG0024	Methionine aminopeptidase
JMB28_RS05240	COG4585	Histidine kinase
JMB28_RS05245	COG2197	response regulator
JMB28_RS05250	COG1295	ribonuclease BN
JMB28_RS05260	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
JMB28_RS05265	COG4840	Belongs to the UPF0435 family
JMB28_RS05270	COG2309	aminopeptidase activity
JMB28_RS05275	COG1607	acyl-coa hydrolase
JMB28_RS05280	COG0535	radical SAM domain protein
JMB28_RS05290	COG0693	protein deglycase activity
JMB28_RS05295	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
JMB28_RS05300	COG2137	regulation of response to DNA damage stimulus
JMB28_RS05310	COG1134	teichoic acid transport
JMB28_RS05320	COG1988	membrane-bound metal-dependent
JMB28_RS05325	COG1194	a g-specific adenine glycosylase
JMB28_RS05330	COG3557	Belongs to the UPF0374 family
JMB28_RS05340	COG4129	membrane
JMB28_RS05345	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
JMB28_RS05350	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
JMB28_RS05355	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
JMB28_RS05360	COG0735	belongs to the Fur family
JMB28_RS05515	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
JMB28_RS05530	COG0765	amino acid transport
JMB28_RS05535	COG1126	abc transporter atp-binding protein
JMB28_RS05540	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
JMB28_RS05550	COG0363	glucosamine-6-phosphate deaminase activity
JMB28_RS05565	COG0114	fumarate hydratase activity
JMB28_RS05575	COG0564	pseudouridine synthase activity
JMB28_RS05580	COG4585	Histidine kinase
JMB28_RS05580	COG2203	Gaf domain
JMB28_RS05585	COG2197	response regulator
JMB28_RS05590	COG1301	dicarboxylic acid transport
JMB28_RS05595	COG0772	Belongs to the SEDS family
JMB28_RS05600	COG1316	TRANSCRIPTIONal
JMB28_RS05605	COG0730	response to heat
JMB28_RS05615	COG1682	transport, permease protein
JMB28_RS05620	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
JMB28_RS05630	COG0788	formyltetrahydrofolate deformylase activity
JMB28_RS05640	COG4399	Belongs to the UPF0754 family
JMB28_RS05645	COG3679	Belongs to the UPF0342 family
JMB28_RS05650	COG0420	3'-5' exonuclease activity
JMB28_RS05655	COG4717	serine-type aminopeptidase activity
JMB28_RS05660	COG3481	metal-dependent phosphohydrolase, HD sub domain
JMB28_RS05665	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
JMB28_RS05680	COG0537	adenosine 5'-monophosphoramidase activity
JMB28_RS05685	COG1131	(ABC) transporter
JMB28_RS05690	COG4473	ABC transporter
JMB28_RS05695	COG2329	Antibiotic biosynthesis monooxygenase
JMB28_RS05700	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
JMB28_RS05705	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
JMB28_RS05710	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
JMB28_RS05715	COG3545	Serine hydrolase
JMB28_RS05795	COG0318	PFAM AMP-dependent synthetase and ligase
JMB28_RS05805	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
JMB28_RS05815	COG1506	peptidase
JMB28_RS05820	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
JMB28_RS05825	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
JMB28_RS05835	COG0656	L-ascorbic acid biosynthetic process
JMB28_RS05840	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
JMB28_RS05845	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
JMB28_RS05855	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
JMB28_RS05875	COG1595	DNA-templated transcription, initiation
JMB28_RS05885	COG4193	domain, Protein
JMB28_RS05885	COG3266	domain, Protein
JMB28_RS05885	COG5632	N-Acetylmuramoyl-L-alanine amidase
JMB28_RS05900	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
JMB28_RS05900	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
JMB28_RS05905	COG0307	riboflavin synthase, alpha
JMB28_RS05910	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
JMB28_RS05910	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
JMB28_RS05915	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
JMB28_RS05925	COG2267	carboxylic ester hydrolase activity
JMB28_RS05930	COG0039	L-malate dehydrogenase activity
JMB28_RS05940	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
JMB28_RS05945	COG1242	4 iron, 4 sulfur cluster binding
JMB28_RS05950	COG2814	Major facilitator Superfamily
JMB28_RS05955	COG0495	leucyl-tRNA aminoacylation
JMB28_RS05965	COG2081	HI0933 family
JMB28_RS05970	COG2244	polysaccharide biosynthetic process
JMB28_RS05975	COG1187	pseudouridine synthase activity
JMB28_RS05985	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
JMB28_RS05990	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
JMB28_RS05995	COG0510	thiamine kinase activity
JMB28_RS06000	COG0220	tRNA (guanine-N7-)-methyltransferase activity
JMB28_RS06005	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JMB28_RS06015	COG1363	Peptidase, m42
JMB28_RS06020	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JMB28_RS06025	COG4848	Belongs to the UPF0354 family
JMB28_RS06030	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JMB28_RS06035	COG1674	ftsk spoiiie
JMB28_RS06040	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
JMB28_RS06045	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
JMB28_RS06055	COG1605	Chorismate mutase
JMB28_RS06055	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
JMB28_RS06060	COG1609	Transcriptional regulator
JMB28_RS06065	COG0123	including yeast histone deacetylase and acetoin utilization protein
JMB28_RS06070	COG0454	-acetyltransferase
JMB28_RS06075	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
JMB28_RS06080	COG2759	Belongs to the formate--tetrahydrofolate ligase family
JMB28_RS06085	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
JMB28_RS06090	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
JMB28_RS06095	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JMB28_RS06100	COG0204	Acyl-transferase
JMB28_RS06105	COG1263	PTS System
JMB28_RS06105	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JMB28_RS06115	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
JMB28_RS06120	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
JMB28_RS06125	COG1764	response to oxidative stress
JMB28_RS06130	COG0584	glycerophosphoryl diester phosphodiesterase
JMB28_RS06140	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
JMB28_RS06145	COG1956	GAF domain-containing protein
JMB28_RS06150	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
JMB28_RS06155	COG1104	cysteine desulfurase activity
JMB28_RS06160	COG0301	tRNA thio-modification
JMB28_RS06170	COG0616	signal peptide processing
JMB28_RS06175	COG1714	RDD family
JMB28_RS06180	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
JMB28_RS06185	COG0827	DNA restriction-modification system
JMB28_RS06190	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
JMB28_RS06200	COG0589	response to stress
JMB28_RS06205	COG0686	Belongs to the AlaDH PNT family
JMB28_RS06210	COG3142	Participates in the control of copper homeostasis
JMB28_RS06215	COG0006	proline dipeptidase activity
JMB28_RS06220	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
JMB28_RS06230	COG4109	DRTGG domain
JMB28_RS06235	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
JMB28_RS06240	COG0587	DNA-directed DNA polymerase activity
JMB28_RS06245	COG0281	malic enzyme
JMB28_RS06250	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
JMB28_RS06255	COG0825	malonyl-CoA metabolic process
JMB28_RS06260	COG0205	6-phosphofructokinase activity
JMB28_RS06265	COG0469	pyruvate kinase activity
JMB28_RS06270	COG1113	amino acid transport
JMB28_RS06275	COG0372	Belongs to the citrate synthase family
JMB28_RS06280	COG0538	isocitrate dehydrogenase activity
JMB28_RS06285	COG0745	RESPONSE REGULATOR receiver
JMB28_RS06290	COG5002	protein histidine kinase activity
JMB28_RS06295	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
JMB28_RS06295	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
JMB28_RS06305	COG0237	dephospho-CoA kinase activity
JMB28_RS06310	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
JMB28_RS06315	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
JMB28_RS06325	COG1484	DNA-dependent DNA replication
JMB28_RS06330	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
JMB28_RS06335	COG0833	amino acid
JMB28_RS06340	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
JMB28_RS06345	COG0291	Belongs to the bacterial ribosomal protein bL35 family
JMB28_RS06350	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
JMB28_RS06355	COG4112	unkown
JMB28_RS06365	COG0544	peptidyl-prolyl cis-trans isomerase activity
JMB28_RS06370	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
JMB28_RS06375	COG0218	Necessary for normal cell division and for the maintenance of normal septation
JMB28_RS06380	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
JMB28_RS06385	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
JMB28_RS06390	COG0181	hydroxymethylbilane synthase activity
JMB28_RS06400	COG0113	porphobilinogen synthase activity
JMB28_RS06405	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
JMB28_RS06415	COG2818	Glycosylase
JMB28_RS06420	COG0525	valine-tRNA ligase activity
JMB28_RS06425	COG0285	dihydrofolate synthase activity
JMB28_RS06440	COG2003	Belongs to the UPF0758 family
JMB28_RS06475	COG0261	This protein binds to 23S rRNA in the presence of protein L20
JMB28_RS06480	COG2868	ribosomal protein
JMB28_RS06485	COG0211	Belongs to the bacterial ribosomal protein bL27 family
JMB28_RS06490	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
JMB28_RS06495	COG4492	Belongs to the UPF0735 family
JMB28_RS06500	COG0632	four-way junction helicase activity
JMB28_RS06505	COG2255	four-way junction helicase activity
JMB28_RS06510	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
JMB28_RS06515	COG0343	queuine tRNA-ribosyltransferase activity
JMB28_RS06520	COG1862	Preprotein translocase
JMB28_RS06525	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
JMB28_RS06525	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
JMB28_RS06530	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
JMB28_RS06530	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
JMB28_RS06540	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
JMB28_RS06545	COG1490	D-aminoacyl-tRNA deacylase activity
JMB28_RS06550	COG0860	N-Acetylmuramoyl-L-alanine amidase
JMB28_RS06555	COG0124	histidyl-tRNA synthetase
JMB28_RS06560	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
JMB28_RS06570	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
JMB28_RS06575	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
JMB28_RS06580	COG1959	2 iron, 2 sulfur cluster binding
JMB28_RS06595	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JMB28_RS06600	COG0488	(ABC) transporter
JMB28_RS06605	COG1104	cysteine desulfurase activity
JMB28_RS06610	COG0482	sulfurtransferase activity
JMB28_RS06620	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
JMB28_RS06625	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
JMB28_RS06630	COG4472	Bacterial protein of unknown function (DUF965)
JMB28_RS06635	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
JMB28_RS06640	COG3906	Belongs to the UPF0473 family
JMB28_RS06645	COG4122	O-methyltransferase activity
JMB28_RS06650	COG0826	peptidase U32
JMB28_RS06655	COG0826	peptidase U32
JMB28_RS06660	COG0572	uridine kinase
JMB28_RS06665	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
JMB28_RS06670	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
JMB28_RS06675	COG1984	allophanate hydrolase subunit 2
JMB28_RS06685	COG0439	Biotin carboxylase
JMB28_RS06690	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
JMB28_RS06695	COG1914	H( )-stimulated, divalent metal cation uptake system
JMB28_RS06700	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
JMB28_RS06705	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
JMB28_RS06710	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
JMB28_RS06715	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
JMB28_RS06720	COG1534	Rna-binding protein
JMB28_RS06725	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
JMB28_RS06730	COG1713	HD superfamily hydrolase involved in NAD metabolism
JMB28_RS06735	COG0799	negative regulation of ribosome biogenesis
JMB28_RS06740	COG2226	methyltransferase
JMB28_RS06745	COG1555	photosystem II stabilization
JMB28_RS06750	COG2131	deaminase
JMB28_RS06755	COG0658	competence protein
JMB28_RS06755	COG2333	competence protein COMEC
JMB28_RS06760	COG1466	dna polymerase III delta subunit
JMB28_RS06765	COG0268	Binds directly to 16S ribosomal RNA
JMB28_RS06770	COG0481	GTPase activity
JMB28_RS06775	COG0635	Involved in the biosynthesis of porphyrin-containing compound
JMB28_RS06780	COG1420	regulation of RNA biosynthetic process
JMB28_RS06785	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
JMB28_RS06790	COG0443	Heat shock 70 kDa protein
JMB28_RS06795	COG0484	heat shock protein binding
JMB28_RS06800	COG2264	protein methyltransferase activity
JMB28_RS06805	COG1385	rRNA (uridine-N3-)-methyltransferase activity
JMB28_RS06810	COG0828	Belongs to the bacterial ribosomal protein bS21 family
JMB28_RS06815	COG1030	water channel activity
JMB28_RS06820	COG4864	UPF0365 protein
JMB28_RS06830	COG1702	phosphate starvation-inducible protein PhoH
JMB28_RS06835	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
JMB28_RS06840	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
JMB28_RS06850	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
JMB28_RS06855	COG1381	Involved in DNA repair and RecF pathway recombination
JMB28_RS06860	COG0423	glycine-tRNA ligase activity
JMB28_RS06865	COG0517	IMP dehydrogenase activity
JMB28_RS06870	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
JMB28_RS06880	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
JMB28_RS06895	COG0513	Belongs to the DEAD box helicase family
JMB28_RS06900	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
JMB28_RS06905	COG1121	(ABC) transporter
JMB28_RS06910	COG1108	ABC-type Mn2 Zn2 transport systems permease components
JMB28_RS06920	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
JMB28_RS06925	COG0768	penicillin binding
JMB28_RS06930	COG0267	Belongs to the bacterial ribosomal protein bL33 family
JMB28_RS06935	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
JMB28_RS06940	COG0705	Rhomboid family
JMB28_RS06940	COG0457	Tetratricopeptide repeat
JMB28_RS06945	COG4483	Protein conserved in bacteria
JMB28_RS06950	COG1940	carbohydrate kinase activity
JMB28_RS06955	COG0011	TIGRFAM Protein of
JMB28_RS06960	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JMB28_RS06965	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
JMB28_RS06995	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
JMB28_RS07000	COG0404	The glycine cleavage system catalyzes the degradation of glycine
JMB28_RS07005	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
JMB28_RS07010	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
JMB28_RS07015	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
JMB28_RS07020	COG0095	Lipoate-protein ligase
JMB28_RS07035	COG0006	proline dipeptidase activity
JMB28_RS07040	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
JMB28_RS07045	COG0511	ligase activity, forming carbon-carbon bonds
JMB28_RS07050	COG0439	Biotin carboxylase
JMB28_RS07055	COG1302	Protein conserved in bacteria
JMB28_RS07060	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
JMB28_RS07065	COG1570	exodeoxyribonuclease VII activity
JMB28_RS07070	COG1722	exodeoxyribonuclease VII activity
JMB28_RS07080	COG1438	arginine binding
JMB28_RS07085	COG0497	DNA recombination
JMB28_RS07090	COG0280	phosphate acetyltransferase
JMB28_RS07100	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
JMB28_RS07105	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
JMB28_RS07110	COG0022	dehydrogenase e1 component
JMB28_RS07115	COG0508	dehydrogenase complex catalyzes the overall conversion of
JMB28_RS07125	COG4129	membrane
JMB28_RS07130	COG2195	Cleaves the N-terminal amino acid of tripeptides
JMB28_RS07140	COG1609	Transcriptional regulator
JMB28_RS07145	COG0366	Alpha amylase catalytic
JMB28_RS07155	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
JMB28_RS07160	COG1234	tRNA 3'-trailer cleavage
JMB28_RS07165	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
JMB28_RS07175	COG0667	Aldo Keto reductase
JMB28_RS07180	COG0494	nUDIX hydrolase
JMB28_RS07185	COG0735	belongs to the Fur family
JMB28_RS07190	COG4974	Belongs to the 'phage' integrase family
JMB28_RS07200	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
JMB28_RS07205	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
JMB28_RS07210	COG1187	pseudouridine synthase activity
JMB28_RS07215	COG0745	RESPONSE REGULATOR receiver
JMB28_RS07235	COG1141	Ferredoxin
JMB28_RS07245	COG0514	ATP-dependent DNA helicase (RecQ)
JMB28_RS07250	COG1388	LysM domain
JMB28_RS07250	COG1388	LysM domain
JMB28_RS07255	COG0492	ferredoxin-NADP+ reductase activity
JMB28_RS07265	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
JMB28_RS07270	COG0539	negative regulation of cytoplasmic translation
JMB28_RS07275	COG1160	GTP binding
JMB28_RS07280	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
JMB28_RS07295	COG2226	methyltransferase
JMB28_RS07300	COG0142	geranyltranstransferase activity
JMB28_RS07305	COG0105	UTP biosynthetic process
JMB28_RS07310	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
JMB28_RS07315	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
JMB28_RS07320	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
JMB28_RS07330	COG5582	Belongs to the UPF0302 family
JMB28_RS07335	COG4347	Protein of unknown function (DUF1405)
JMB28_RS07340	COG2738	Putative neutral zinc metallopeptidase
JMB28_RS07345	COG1694	Mazg nucleotide pyrophosphohydrolase
JMB28_RS07350	COG0438	transferase activity, transferring glycosyl groups
JMB28_RS07355	COG0617	tRNA 3'-terminal CCA addition
JMB28_RS07365	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
JMB28_RS07365	COG1199	ATP-dependent helicase activity
JMB28_RS07370	COG0017	Asparaginyl-tRNA synthetase
JMB28_RS07375	COG3935	DnaD domain protein
JMB28_RS07380	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
JMB28_RS07390	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
JMB28_RS07390	COG4499	WXG100 protein secretion system (Wss), protein YukC
JMB28_RS07395	COG3331	DNA recombination
JMB28_RS07405	COG4474	Belongs to the UPF0398 family
JMB28_RS07420	COG0116	Belongs to the methyltransferase superfamily
JMB28_RS07425	COG2962	Rard protein
JMB28_RS07435	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
JMB28_RS07440	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
JMB28_RS07445	COG0328	RNA-DNA hybrid ribonuclease activity
JMB28_RS07450	COG3545	Serine hydrolase
JMB28_RS07455	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
JMB28_RS07465	COG1413	lyase activity
JMB28_RS07470	COG1413	lyase activity
JMB28_RS07480	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
JMB28_RS07500	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
JMB28_RS07510	COG4479	Belongs to the UPF0346 family
JMB28_RS07515	COG0793	Belongs to the peptidase S41A family
JMB28_RS07525	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
JMB28_RS07530	COG0671	phosphoesterase, PA-phosphatase related
JMB28_RS07535	COG0745	RESPONSE REGULATOR receiver
JMB28_RS07540	COG5002	protein histidine kinase activity
JMB28_RS07545	COG0567	Dehydrogenase, E1 component
JMB28_RS07550	COG0508	dehydrogenase complex catalyzes the overall conversion of
JMB28_RS07555	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
JMB28_RS07565	COG1917	Cupin 2, conserved barrel domain protein
JMB28_RS07565	COG2207	Transcriptional regulator
JMB28_RS07580	COG0673	inositol 2-dehydrogenase activity
JMB28_RS07585	COG0673	inositol 2-dehydrogenase activity
JMB28_RS07595	COG1131	(ABC) transporter
JMB28_RS07620	COG0714	Associated with various cellular activities
JMB28_RS07625	COG4548	von Willebrand factor, type A
JMB28_RS07630	COG1114	Component of the transport system for branched-chain amino acids
JMB28_RS07635	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
JMB28_RS07640	COG3853	Toxic anion resistance protein (TelA)
JMB28_RS07650	COG1254	Belongs to the acylphosphatase family
JMB28_RS07660	COG1278	Cold shock
JMB28_RS07675	COG1473	amidohydrolase
JMB28_RS07685	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
JMB28_RS07690	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
JMB28_RS07695	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
JMB28_RS07700	COG0527	aspartate kinase activity
JMB28_RS07710	COG0488	(ABC) transporter
JMB28_RS07715	COG2996	Protein conserved in bacteria
JMB28_RS07720	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
JMB28_RS07725	COG0573	inorganic phosphate transmembrane transporter activity
JMB28_RS07730	COG0581	inorganic phosphate transmembrane transporter activity
JMB28_RS07735	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
JMB28_RS07745	COG1164	Oligoendopeptidase f
JMB28_RS07755	COG4607	ABC-type enterochelin transport system periplasmic component
JMB28_RS07770	COG2348	transferase activity, transferring amino-acyl groups
JMB28_RS07780	COG0159	tryptophan synthase activity
JMB28_RS07785	COG0133	tryptophan synthase activity
JMB28_RS07795	COG0134	indole-3-glycerol-phosphate synthase activity
JMB28_RS07800	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
JMB28_RS07805	COG0512	Glutamine amidotransferase of anthranilate synthase
JMB28_RS07810	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
JMB28_RS07825	COG1280	lysine exporter protein (LysE YggA)
JMB28_RS07835	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
JMB28_RS07835	COG0463	Glycosyl transferase, family 2
JMB28_RS07840	COG0463	Glycosyl transferase, family 2
JMB28_RS07855	COG1363	Peptidase, m42
JMB28_RS07865	COG0287	Prephenate dehydrogenase
JMB28_RS07870	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
JMB28_RS07875	COG1942	4-Oxalocrotonate Tautomerase
JMB28_RS07895	COG1879	ABC-type sugar transport system periplasmic component
JMB28_RS07905	COG1129	ABC transporter
JMB28_RS07910	COG1869	D-ribose catabolic process
JMB28_RS07915	COG1609	Transcriptional regulator
JMB28_RS07920	COG0392	lysyltransferase activity
JMB28_RS07920	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
JMB28_RS07925	COG0628	permease
JMB28_RS07935	COG3711	transcriptional antiterminator
JMB28_RS07940	COG1115	amino acid carrier protein
JMB28_RS07945	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
JMB28_RS07955	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
JMB28_RS07960	COG4841	protein insertion into membrane
JMB28_RS07965	COG0824	Thioesterase
JMB28_RS07970	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
JMB28_RS07975	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
JMB28_RS07980	COG1970	mechanosensitive ion channel activity
JMB28_RS07985	COG0419	ATPase involved in DNA repair
JMB28_RS07990	COG0420	3'-5' exonuclease activity
JMB28_RS07995	COG4846	Membrane protein involved in cytochrome C biogenesis
JMB28_RS08005	COG3763	UPF0154 protein
JMB28_RS08025	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
JMB28_RS08035	COG0516	GMP reductase activity
JMB28_RS08040	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
JMB28_RS08045	COG0267	Belongs to the bacterial ribosomal protein bL33 family
JMB28_RS08050	COG0753	catalase activity
JMB28_RS08055	COG0833	amino acid
JMB28_RS08070	COG0561	phosphatase activity
JMB28_RS08075	COG0083	homoserine kinase activity
JMB28_RS08080	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
JMB28_RS08085	COG0460	homoserine dehydrogenase
JMB28_RS08090	COG0527	aspartate kinase activity
JMB28_RS08120	COG2197	response regulator
JMB28_RS08125	COG4585	Histidine kinase
JMB28_RS08130	COG0842	Transport permease protein
JMB28_RS08135	COG1131	(ABC) transporter
JMB28_RS08140	COG3708	Transcriptional regulator
JMB28_RS08140	COG2207	Transcriptional regulator
JMB28_RS08150	COG1764	response to oxidative stress
JMB28_RS08165	COG0789	Transcriptional regulator
JMB28_RS08170	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
JMB28_RS08175	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
JMB28_RS08180	COG0386	Belongs to the glutathione peroxidase family
JMB28_RS08185	COG1923	regulation of RNA biosynthetic process
JMB28_RS08190	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
JMB28_RS08200	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
JMB28_RS08205	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
JMB28_RS08210	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
JMB28_RS08215	COG1619	proteins homologs of microcin C7 resistance protein MccF
JMB28_RS08225	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
JMB28_RS08230	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
JMB28_RS08240	COG4550	Control of competence regulator ComK, YlbF/YmcA
JMB28_RS08245	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
JMB28_RS08255	COG0492	ferredoxin-NADP+ reductase activity
JMB28_RS08260	COG1959	2 iron, 2 sulfur cluster binding
JMB28_RS08265	COG4195	phage-related replication protein
JMB28_RS08275	COG1013	pyruvate-flavodoxin oxidoreductase activity
JMB28_RS08280	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
JMB28_RS08280	COG0674	pyruvate-flavodoxin oxidoreductase activity
JMB28_RS08285	COG1692	metallophosphoesterase
JMB28_RS08295	COG1418	mRNA catabolic process
JMB28_RS08300	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
JMB28_RS08305	COG1058	Belongs to the CinA family
JMB28_RS08305	COG1546	Belongs to the CinA family
JMB28_RS08325	COG0300	oxidoreductase activity
JMB28_RS08330	COG0612	Peptidase, M16
JMB28_RS08335	COG0612	Peptidase, M16
JMB28_RS08340	COG2188	Transcriptional regulator
JMB28_RS08350	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
JMB28_RS08355	COG1185	polyribonucleotide nucleotidyltransferase activity
JMB28_RS08360	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
JMB28_RS08365	COG0196	riboflavin kinase activity
JMB28_RS08370	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
JMB28_RS08375	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
JMB28_RS08390	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
JMB28_RS08395	COG1358	cellular component organization or biogenesis
JMB28_RS08400	COG2740	Nucleic-acid-binding protein implicated in transcription termination
JMB28_RS08405	COG0195	Participates in both transcription termination and antitermination
JMB28_RS08410	COG0779	Required for maturation of 30S ribosomal subunits
JMB28_RS08415	COG2176	DNA-directed DNA polymerase activity
JMB28_RS08420	COG0442	prolyl-tRNA aminoacylation
JMB28_RS08430	COG4589	Belongs to the CDS family
JMB28_RS08435	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
JMB28_RS08440	COG0233	cytoplasmic translational termination
JMB28_RS08445	COG0528	UMP kinase activity
JMB28_RS08450	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
JMB28_RS08460	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
JMB28_RS08465	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
JMB28_RS08470	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
JMB28_RS08475	COG4974	Belongs to the 'phage' integrase family
JMB28_RS08480	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
JMB28_RS08485	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
JMB28_RS08490	COG0758	DNA mediated transformation
JMB28_RS08500	COG0045	succinate-CoA ligase (ADP-forming) activity
JMB28_RS08505	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
JMB28_RS08515	COG4485	Bacterial membrane protein, YfhO
JMB28_RS08525	COG0335	large ribosomal subunit rRNA binding
JMB28_RS08530	COG0336	Belongs to the RNA methyltransferase TrmD family
JMB28_RS08535	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
JMB28_RS08540	COG0228	four-way junction DNA binding
JMB28_RS08545	COG1028	Short-chain dehydrogenase reductase Sdr
JMB28_RS08550	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JMB28_RS08555	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
JMB28_RS08560	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
JMB28_RS08565	COG0552	protein localization to endoplasmic reticulum
JMB28_RS08570	COG1196	nuclear chromosome segregation
JMB28_RS08575	COG0571	ribonuclease III activity
JMB28_RS08580	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
JMB28_RS08595	COG0416	fatty acid biosynthetic process
JMB28_RS08600	COG1349	DNA-binding transcription factor activity
JMB28_RS08610	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
JMB28_RS08615	COG1760	l-serine dehydratase
JMB28_RS08620	COG1760	l-serine dehydratase
JMB28_RS08625	COG1461	Dihydroxyacetone kinase
JMB28_RS08630	COG1302	Protein conserved in bacteria
JMB28_RS08635	COG0227	Belongs to the bacterial ribosomal protein bL28 family
JMB28_RS08640	COG1564	THIamine pyrophosphokinase
JMB28_RS08645	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
JMB28_RS08650	COG1162	GTPase activity
JMB28_RS08665	COG0820	rRNA (adenine-C2-)-methyltransferase activity
JMB28_RS08670	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
JMB28_RS08670	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
JMB28_RS08675	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
JMB28_RS08680	COG0242	peptide deformylase activity
JMB28_RS08695	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
JMB28_RS08700	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
JMB28_RS08705	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
JMB28_RS08710	COG1758	RNA polymerase activity
JMB28_RS08715	COG0194	GDP metabolic process
JMB28_RS08720	COG1293	RNA-binding protein homologous to eukaryotic snRNP
JMB28_RS08735	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
JMB28_RS08740	COG3173	Aminoglycoside phosphotransferase
JMB28_RS08750	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
JMB28_RS08755	COG0284	orotidine-5'-phosphate decarboxylase activity
JMB28_RS08760	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
JMB28_RS08765	COG0505	Belongs to the CarA family
JMB28_RS08775	COG0540	Belongs to the ATCase OTCase family
JMB28_RS08785	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
JMB28_RS08790	COG0564	pseudouridine synthase activity
JMB28_RS08795	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
JMB28_RS08805	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
JMB28_RS08810	COG3599	regulation of cell shape
JMB28_RS08820	COG0762	integral membrane protein
JMB28_RS08825	COG1799	cell septum assembly
JMB28_RS08830	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
JMB28_RS08835	COG1496	oxidoreductase activity
JMB28_RS08840	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
JMB28_RS08845	COG0849	cell division
JMB28_RS08855	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
JMB28_RS08860	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
JMB28_RS08865	COG0768	penicillin binding
JMB28_RS08870	COG4839	cell division protein FtsL
JMB28_RS08875	COG0275	rRNA processing
JMB28_RS08880	COG2001	Belongs to the MraZ family
JMB28_RS08885	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
JMB28_RS08890	COG0454	-acetyltransferase
JMB28_RS08895	COG1011	Hydrolase
JMB28_RS08950	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
JMB28_RS08955	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
JMB28_RS08960	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
JMB28_RS08965	COG1053	succinate dehydrogenase
JMB28_RS08970	COG2009	succinate dehydrogenase
JMB28_RS08975	COG0322	excinuclease ABC activity
JMB28_RS08980	COG3118	belongs to the thioredoxin family
JMB28_RS08985	COG1193	negative regulation of DNA recombination
JMB28_RS08990	COG1796	DNA polymerase
JMB28_RS08990	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
JMB28_RS09000	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
JMB28_RS09005	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
JMB28_RS09010	COG0072	phenylalanine-tRNA ligase activity
JMB28_RS09015	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
JMB28_RS09020	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
JMB28_RS09030	COG0333	Belongs to the bacterial ribosomal protein bL32 family
JMB28_RS09040	COG1323	Belongs to the UPF0348 family
JMB28_RS09045	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
JMB28_RS09050	COG0742	ribosomal rna small subunit methyltransferase
JMB28_RS09060	COG4471	UPF0298 protein
JMB28_RS09065	COG0584	glycerophosphoryl diester phosphodiesterase
JMB28_RS09070	COG3679	Belongs to the UPF0342 family
JMB28_RS09090	COG0109	protoheme IX farnesyltransferase activity
JMB28_RS09095	COG1612	heme a metabolic process
JMB28_RS09105	COG0772	Belongs to the SEDS family
JMB28_RS09115	COG4838	Belongs to the UPF0358 family
JMB28_RS09120	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
JMB28_RS09125	COG4896	Protein conserved in bacteria
JMB28_RS09130	COG1217	gtp-binding protein TYPA
JMB28_RS09140	COG0483	inositol monophosphate 1-phosphatase activity
JMB28_RS09145	COG4493	Belongs to the UPF0637 family
JMB28_RS09160	COG1914	H( )-stimulated, divalent metal cation uptake system
JMB28_RS09175	COG1177	transmembrane transport
JMB28_RS09180	COG1176	ABC-type spermidine putrescine transport system, permease component I
JMB28_RS09185	COG3842	ATPase activity
JMB28_RS09195	COG4476	Belongs to the UPF0223 family
JMB28_RS09235	COG5503	Protein of unknown function (DUF1447)
JMB28_RS09245	COG0569	domain protein
JMB28_RS09250	COG1294	oxidase, subunit
JMB28_RS09255	COG1271	oxidase subunit
JMB28_RS09265	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
JMB28_RS09270	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
JMB28_RS09280	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
JMB28_RS09300	COG4172	Belongs to the ABC transporter superfamily
JMB28_RS09310	COG0151	Belongs to the GarS family
JMB28_RS09315	COG0138	bifunctional purine biosynthesis protein purh
JMB28_RS09325	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
JMB28_RS09335	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
JMB28_RS09340	COG0047	phosphoribosylformylglycinamidine synthase activity
JMB28_RS09345	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
JMB28_RS09350	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
JMB28_RS09355	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
JMB28_RS09360	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
JMB28_RS09365	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
JMB28_RS09370	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
JMB28_RS09370	COG1017	nitric oxide dioxygenase activity
JMB28_RS09380	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
JMB28_RS09385	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
JMB28_RS09390	COG1845	cytochrome c oxidase, subunit III
JMB28_RS09395	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
JMB28_RS09410	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
JMB28_RS09415	COG1316	TRANSCRIPTIONal
JMB28_RS09440	COG3594	Acyltransferase
JMB28_RS09445	COG0436	Aminotransferase
JMB28_RS09450	COG1846	Transcriptional regulator
JMB28_RS09455	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
JMB28_RS09460	COG2267	carboxylic ester hydrolase activity
JMB28_RS09465	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
JMB28_RS09470	COG1169	isochorismate synthase
JMB28_RS09475	COG1575	Belongs to the MenA family. Type 1 subfamily
JMB28_RS09485	COG2314	TM2 domain
JMB28_RS09510	COG4903	ComK protein
JMB28_RS09525	COG4873	Protein conserved in bacteria
JMB28_RS09535	COG0737	Belongs to the 5'-nucleotidase family
JMB28_RS09540	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
JMB28_RS09545	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JMB28_RS09565	COG1012	belongs to the aldehyde dehydrogenase family
JMB28_RS09570	COG2124	cytochrome p450
JMB28_RS09575	COG0861	Integral membrane protein TerC family
JMB28_RS09580	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
JMB28_RS09590	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
JMB28_RS09595	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
JMB28_RS09600	COG2814	Major facilitator Superfamily
JMB28_RS09605	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
JMB28_RS09610	COG2382	esterase
JMB28_RS09615	COG1115	amino acid carrier protein
JMB28_RS09620	COG0628	permease
JMB28_RS09635	COG0569	domain protein
JMB28_RS09635	COG0475	glutathione-regulated potassium exporter activity
JMB28_RS09640	COG2239	Acts as a magnesium transporter
JMB28_RS09645	COG0564	pseudouridine synthase activity
JMB28_RS09650	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
JMB28_RS09655	COG2357	RelA SpoT domain protein
JMB28_RS09670	COG2346	COG2346, Truncated hemoglobins
JMB28_RS09675	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
JMB28_RS09680	COG1164	Oligoendopeptidase f
JMB28_RS09690	COG4862	establishment of competence for transformation
JMB28_RS09695	COG1393	Belongs to the ArsC family
JMB28_RS09700	COG0180	Tryptophanyl-tRNA synthetase
JMB28_RS09705	COG4166	transmembrane transport
JMB28_RS09710	COG4608	Belongs to the ABC transporter superfamily
JMB28_RS09720	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JMB28_RS09725	COG0601	transmembrane transport
JMB28_RS09745	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
JMB28_RS09780	COG0561	phosphatase activity
JMB28_RS09785	COG0446	pyridine nucleotide-disulphide oxidoreductase
JMB28_RS09805	COG0179	Fumarylacetoacetate (FAA) hydrolase
JMB28_RS09810	COG2311	Membrane
JMB28_RS09815	COG1074	ATP-dependent DNA helicase activity
JMB28_RS09820	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
JMB28_RS09835	COG0398	Pfam SNARE associated Golgi protein
JMB28_RS09840	COG0166	Belongs to the GPI family
JMB28_RS09845	COG0137	argininosuccinate synthase activity
JMB28_RS09850	COG0165	Argininosuccinate lyase
JMB28_RS09855	COG0584	glycerophosphoryl diester phosphodiesterase
JMB28_RS09865	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
JMB28_RS09870	COG1902	pentaerythritol trinitrate reductase activity
JMB28_RS09875	COG1098	S1 RNA binding domain
JMB28_RS09880	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
JMB28_RS09890	COG2111	Na H antiporter
JMB28_RS09890	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
JMB28_RS09895	COG2111	Na H antiporter
JMB28_RS09900	COG1006	Multisubunit Na H antiporter MnhC subunit
JMB28_RS09905	COG0651	ATP synthesis coupled electron transport
JMB28_RS09910	COG1863	multisubunit Na H antiporter MnhE subunit
JMB28_RS09915	COG2212	antiporter activity
JMB28_RS09920	COG1320	monovalent cation:proton antiporter activity
JMB28_RS09930	COG2050	protein possibly involved in aromatic compounds catabolism
JMB28_RS09935	COG2056	Na+-H+ antiporter family
JMB28_RS09940	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
JMB28_RS09945	COG1252	NADH dehydrogenase
JMB28_RS09950	COG0316	Belongs to the HesB IscA family
JMB28_RS09955	COG4844	belongs to the
JMB28_RS09960	COG1252	NADH dehydrogenase
JMB28_RS09965	COG4837	Protein of unknown function (DUF1462)
JMB28_RS09970	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
JMB28_RS09975	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
JMB28_RS09980	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
JMB28_RS09985	COG1696	Membrane protein involved in D-alanine export
JMB28_RS09990	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
JMB28_RS10000	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
JMB28_RS10005	COG0647	UMP catabolic process
JMB28_RS10010	COG2445	Protein of unknown function DUF86
JMB28_RS10020	COG4470	Protein conserved in bacteria
JMB28_RS10025	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
JMB28_RS10030	COG0737	Belongs to the 5'-nucleotidase family
JMB28_RS10035	COG0730	response to heat
JMB28_RS10040	COG1801	Protein of unknown function DUF72
JMB28_RS10045	COG2070	2-Nitropropane dioxygenase
JMB28_RS10050	COG1253	flavin adenine dinucleotide binding
JMB28_RS10055	COG0454	-acetyltransferase
JMB28_RS10060	COG0719	Fe-S assembly protein
JMB28_RS10065	COG0822	iron-sulfur transferase activity
JMB28_RS10070	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
JMB28_RS10075	COG0719	Fe-S assembly protein
JMB28_RS10080	COG0396	ATPase activity
JMB28_RS10090	COG1253	flavin adenine dinucleotide binding
JMB28_RS10170	COG1464	Belongs to the NlpA lipoprotein family
JMB28_RS10175	COG2011	ABC-type metal ion transport system permease component
JMB28_RS10180	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
JMB28_RS10185	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JMB28_RS10190	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
JMB28_RS10195	COG0509	glycine decarboxylation via glycine cleavage system
JMB28_RS10200	COG1393	Belongs to the ArsC family
JMB28_RS10205	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JMB28_RS10210	COG0778	Nitroreductase
JMB28_RS10215	COG0710	3-dehydroquinate dehydratase activity
JMB28_RS10220	COG1764	response to oxidative stress
JMB28_RS10235	COG2851	Citrate transporter
JMB28_RS10250	COG2314	TM2 domain
JMB28_RS10290	COG2153	protein acetylation
JMB28_RS10295	COG0346	lactoylglutathione lyase activity
JMB28_RS10310	COG1073	alpha beta
JMB28_RS10360	COG0346	lactoylglutathione lyase activity
JMB28_RS10385	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
JMB28_RS10450	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
JMB28_RS10455	COG0557	exoribonuclease II activity
JMB28_RS10460	COG1647	Serine aminopeptidase, S33
JMB28_RS10465	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
JMB28_RS10475	COG0148	phosphopyruvate hydratase activity
JMB28_RS10480	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
JMB28_RS10485	COG0149	triose-phosphate isomerase activity
JMB28_RS10490	COG0126	phosphoglycerate kinase activity
JMB28_RS10525	COG1090	epimerase
JMB28_RS10535	COG0740	serine-type endopeptidase activity
JMB28_RS10545	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
JMB28_RS10550	COG1481	regulation of sporulation
JMB28_RS10555	COG0391	Required for morphogenesis under gluconeogenic growth conditions
JMB28_RS10560	COG1660	Displays ATPase and GTPase activities
JMB28_RS10565	COG0492	ferredoxin-NADP+ reductase activity
JMB28_RS10575	COG0110	maltose O-acetyltransferase activity
JMB28_RS10580	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
JMB28_RS10585	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
JMB28_RS10595	COG0556	nucleotide-excision repair
JMB28_RS10610	COG3942	CHAP domain
JMB28_RS10610	COG1388	LysM domain
JMB28_RS10620	COG0653	protein targeting
JMB28_RS10625	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
JMB28_RS10630	COG1040	competence protein
JMB28_RS10635	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
JMB28_RS10645	COG1739	Uncharacterized protein family UPF0029
JMB28_RS10650	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
JMB28_RS10655	COG2199	diguanylate cyclase activity
JMB28_RS10670	COG2195	Cleaves the N-terminal amino acid of tripeptides
JMB28_RS10680	COG1929	Belongs to the glycerate kinase type-1 family
JMB28_RS10700	COG0812	UDP-N-acetylmuramate dehydrogenase activity
JMB28_RS10715	COG4607	ABC-type enterochelin transport system periplasmic component
JMB28_RS10720	COG4604	ABC transporter, ATP-binding protein
JMB28_RS10725	COG4605	iron ion homeostasis
JMB28_RS10730	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JMB28_RS10735	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
JMB28_RS10740	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
JMB28_RS10745	COG1780	Probably involved in ribonucleotide reductase function
JMB28_RS10755	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
JMB28_RS10760	COG3104	oligopeptide transport
JMB28_RS10765	COG3104	oligopeptide transport
JMB28_RS10770	COG1597	lipid kinase activity
JMB28_RS10780	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
JMB28_RS10785	COG1174	glycine betaine transport
JMB28_RS10795	COG0514	ATP-dependent DNA helicase (RecQ)
JMB28_RS10800	COG0488	(ABC) transporter
JMB28_RS10810	COG1368	sulfuric ester hydrolase activity
JMB28_RS10820	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
JMB28_RS10835	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
JMB28_RS10835	COG0512	Glutamine amidotransferase of anthranilate synthase
JMB28_RS10840	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
JMB28_RS10845	COG0720	synthase
JMB28_RS10850	COG0602	queuosine metabolic process
JMB28_RS10865	COG0463	Glycosyl transferase, family 2
JMB28_RS10870	COG0656	L-ascorbic acid biosynthetic process
JMB28_RS10875	COG1253	flavin adenine dinucleotide binding
JMB28_RS10880	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
JMB28_RS10885	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JMB28_RS10885	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JMB28_RS10885	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JMB28_RS10890	COG1105	Belongs to the carbohydrate kinase PfkB family
JMB28_RS10895	COG1349	DNA-binding transcription factor activity
JMB28_RS10900	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
JMB28_RS10905	COG1210	Utp--glucose-1-phosphate uridylyltransferase
JMB28_RS10930	COG0039	L-malate dehydrogenase activity
JMB28_RS10935	COG0586	Pfam SNARE associated Golgi protein
JMB28_RS10945	COG4989	oxidoreductase activity
JMB28_RS10950	COG0523	cobalamin synthesis protein
JMB28_RS10960	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
JMB28_RS10965	COG4988	ABC transporter
JMB28_RS10970	COG1968	undecaprenyl-diphosphatase activity
JMB28_RS10980	COG1671	Belongs to the UPF0178 family
JMB28_RS10990	COG1279	arginine transmembrane transporter activity
JMB28_RS10995	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JMB28_RS11030	COG2814	Major facilitator Superfamily
JMB28_RS11035	COG2839	Protein conserved in bacteria
JMB28_RS11040	COG2814	Major facilitator Superfamily
JMB28_RS11045	COG0583	DNA-binding transcription factor activity
JMB28_RS11055	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
JMB28_RS11065	COG0217	transcriptional regulatory protein
JMB28_RS11085	COG1388	LysM domain
JMB28_RS11085	COG3942	CHAP domain
JMB28_RS11090	COG0306	phosphate transporter
JMB28_RS11095	COG1392	Phosphate transport regulator
JMB28_RS11100	COG2205	protein histidine kinase activity
JMB28_RS11105	COG0745	RESPONSE REGULATOR receiver
JMB28_RS11110	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
JMB28_RS11120	COG0657	acetylesterase activity
JMB28_RS11125	COG3949	Membrane
JMB28_RS11135	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
JMB28_RS11140	COG1461	Dihydroxyacetone kinase
JMB28_RS11145	COG2376	Dihydroxyacetone kinase
JMB28_RS11150	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JMB28_RS11155	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JMB28_RS11160	COG1120	ATPase activity
JMB28_RS11165	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
JMB28_RS11170	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
JMB28_RS11175	COG1132	(ABC) transporter
JMB28_RS11185	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
JMB28_RS11195	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
JMB28_RS11200	COG1682	transport, permease protein
JMB28_RS11205	COG1134	teichoic acid transport
JMB28_RS11210	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
JMB28_RS11230	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
JMB28_RS11235	COG1522	sequence-specific DNA binding
JMB28_RS11250	COG1108	ABC-type Mn2 Zn2 transport systems permease components
JMB28_RS11255	COG0803	Belongs to the bacterial solute-binding protein 9 family
JMB28_RS11265	COG1320	monovalent cation:proton antiporter activity
JMB28_RS11270	COG2212	antiporter activity
JMB28_RS11275	COG1863	multisubunit Na H antiporter MnhE subunit
JMB28_RS11280	COG0651	ATP synthesis coupled electron transport
JMB28_RS11285	COG1006	Multisubunit Na H antiporter MnhC subunit
JMB28_RS11290	COG2111	Na H antiporter
JMB28_RS11295	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
JMB28_RS11295	COG2111	Na H antiporter
JMB28_RS11300	COG4974	Belongs to the 'phage' integrase family
JMB28_RS11335	COG0596	Alpha beta hydrolase
JMB28_RS11355	COG0546	phosphoglycolate phosphatase activity
JMB28_RS11360	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JMB28_RS11365	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
JMB28_RS11375	COG0018	arginyl-trna synthetase
JMB28_RS11390	COG1078	dGTPase activity
JMB28_RS11400	COG0655	NAD(P)H dehydrogenase (quinone) activity
JMB28_RS11405	COG0667	Aldo Keto reductase
JMB28_RS11410	COG4844	belongs to the
JMB28_RS11415	COG1082	Xylose isomerase domain protein TIM barrel
JMB28_RS11420	COG0673	inositol 2-dehydrogenase activity
JMB28_RS11430	COG0673	inositol 2-dehydrogenase activity
JMB28_RS11435	COG1737	Transcriptional regulator
JMB28_RS11440	COG1263	PTS System
JMB28_RS11440	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JMB28_RS11460	COG0095	Lipoate-protein ligase
JMB28_RS11465	COG0280	phosphate acetyltransferase
JMB28_RS11470	COG3253	May function as heme-dependent peroxidase
JMB28_RS11490	COG2363	Small membrane protein
JMB28_RS11500	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
JMB28_RS11505	COG0351	phosphomethylpyrimidine kinase
JMB28_RS11535	COG0183	Belongs to the thiolase family
JMB28_RS11540	COG0318	PFAM AMP-dependent synthetase and ligase
JMB28_RS11550	COG3493	citrate carrier protein
JMB28_RS11555	COG0384	phenazine biosynthesis protein PhzF
JMB28_RS11585	COG2832	Protein of unknown function (DUF454)
JMB28_RS11590	COG4565	transcriptional regulatory protein
JMB28_RS11595	COG3290	protein histidine kinase activity
JMB28_RS11600	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
JMB28_RS11605	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
JMB28_RS11610	COG0363	glucosamine-6-phosphate deaminase activity
JMB28_RS11620	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
JMB28_RS11625	COG1469	GTP cyclohydrolase I activity
JMB28_RS11640	COG0431	NADPH-dependent FMN reductase
JMB28_RS11645	COG0561	phosphatase activity
JMB28_RS11655	COG1428	Deoxynucleoside kinase
JMB28_RS11660	COG1428	Deoxynucleoside kinase
JMB28_RS11670	COG0546	phosphoglycolate phosphatase activity
JMB28_RS11690	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
JMB28_RS11705	COG2814	Major facilitator Superfamily
JMB28_RS11710	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JMB28_RS11730	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
JMB28_RS11740	COG2824	Alkylphosphonate utilization operon protein PhnA
JMB28_RS11745	COG3832	glyoxalase III activity
JMB28_RS11750	COG1113	amino acid transport
JMB28_RS11755	COG3239	Fatty acid desaturase
JMB28_RS11770	COG2040	homocysteine
JMB28_RS11775	COG0833	amino acid
JMB28_RS11785	COG0010	Belongs to the arginase family
JMB28_RS11790	COG1914	H( )-stimulated, divalent metal cation uptake system
JMB28_RS11800	COG1069	ribulokinase activity
JMB28_RS11805	COG1063	alcohol dehydrogenase
JMB28_RS11810	COG2814	Major facilitator Superfamily
JMB28_RS11815	COG1349	DNA-binding transcription factor activity
JMB28_RS11820	COG1132	(ABC) transporter
JMB28_RS11825	COG1028	Short-chain dehydrogenase reductase Sdr
JMB28_RS11830	COG1312	Catalyzes the dehydration of D-mannonate
JMB28_RS11835	COG1904	glucuronate isomerase
JMB28_RS11855	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JMB28_RS11870	COG0583	DNA-binding transcription factor activity
JMB28_RS11885	COG0667	Aldo Keto reductase
JMB28_RS11915	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
JMB28_RS11945	COG1686	Belongs to the peptidase S11 family
JMB28_RS11960	COG1028	Short-chain dehydrogenase reductase Sdr
JMB28_RS11965	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
JMB28_RS11970	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
JMB28_RS11980	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
JMB28_RS11980	COG0463	Glycosyl transferase, family 2
JMB28_RS12010	COG1473	amidohydrolase
JMB28_RS12015	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
JMB28_RS12020	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
JMB28_RS12025	COG0049	tRNA binding
JMB28_RS12030	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
JMB28_RS12040	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
JMB28_RS12045	COG0085	RNA polymerase activity
JMB28_RS12050	COG2813	Specifically methylates the guanine in position
JMB28_RS12055	COG0222	ribosome binding
JMB28_RS12060	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
JMB28_RS12065	COG0081	regulation of translation
JMB28_RS12070	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
JMB28_RS12075	COG0250	Participates in transcription elongation, termination and antitermination
JMB28_RS12100	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
JMB28_RS12105	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
JMB28_RS12110	COG0215	cysteine-tRNA ligase activity
JMB28_RS12115	COG1045	serine acetyltransferase
JMB28_RS12120	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
JMB28_RS12125	COG4956	integral membrane protein (PIN domain superfamily)
JMB28_RS12130	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
JMB28_RS12135	COG0542	response to heat
JMB28_RS12140	COG3869	Catalyzes the specific phosphorylation of arginine residues in
JMB28_RS12145	COG3880	PFAM UvrB UvrC protein
JMB28_RS12150	COG4463	regulation of RNA biosynthetic process
JMB28_RS12155	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
JMB28_RS12160	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
JMB28_RS12165	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
JMB28_RS12170	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JMB28_RS12255	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
JMB28_RS12260	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
JMB28_RS12280	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
JMB28_RS12285	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
JMB28_RS12300	COG1098	S1 RNA binding domain
JMB28_RS12310	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
JMB28_RS12315	COG3956	TIGRFAM MazG family protein
JMB28_RS12320	COG2244	polysaccharide biosynthetic process
JMB28_RS12325	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
JMB28_RS12330	COG0193	aminoacyl-tRNA hydrolase activity
JMB28_RS12335	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
JMB28_RS12340	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
JMB28_RS12345	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
JMB28_RS12350	COG2088	sporulation resulting in formation of a cellular spore
JMB28_RS12355	COG0251	oxidation-reduction process
JMB28_RS12360	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
JMB28_RS12365	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
JMB28_RS12370	COG4466	Protein conserved in bacteria
JMB28_RS12375	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
JMB28_RS12380	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
JMB28_RS12385	COG0084	hydrolase, TatD family'
JMB28_RS12390	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JMB28_RS12390	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JMB28_RS12395	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
JMB28_RS12400	COG2827	Endonuclease containing a URI domain
JMB28_RS12405	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
JMB28_RS12410	COG4467	Involved in initiation control of chromosome replication
JMB28_RS12415	COG1774	PSP1 C-terminal conserved region
JMB28_RS12420	COG0470	DNA polymerase III
JMB28_RS12425	COG3870	Protein conserved in bacteria
JMB28_RS12430	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
JMB28_RS12435	COG1982	Orn Lys Arg decarboxylase major
JMB28_RS12470	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
JMB28_RS12475	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
JMB28_RS12480	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
JMB28_RS12485	COG3153	acetyltransferase
JMB28_RS12495	COG2188	Transcriptional regulator
JMB28_RS12500	COG0366	Alpha amylase catalytic
JMB28_RS12505	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JMB28_RS12505	COG1263	PTS System
JMB28_RS12515	COG0493	'glutamate synthase
JMB28_RS12520	COG0070	glutamate synthase
JMB28_RS12520	COG0069	glutamate synthase activity
JMB28_RS12520	COG0067	glutamate synthase
JMB28_RS12540	COG0004	ammonium transporteR
JMB28_RS12555	COG1388	LysM domain
JMB28_RS12555	COG3942	CHAP domain
JMB28_RS12565	COG0129	dihydroxy-acid dehydratase activity
JMB28_RS12580	COG0733	neurotransmitter:sodium symporter activity
JMB28_RS12585	COG1114	Component of the transport system for branched-chain amino acids
JMB28_RS12590	COG5646	InterPro IPR014922
JMB28_RS12595	COG2268	Band 7 protein
JMB28_RS12620	COG0789	Transcriptional regulator
JMB28_RS12635	COG4195	phage-related replication protein
JMB28_RS12640	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
JMB28_RS12645	COG2807	transmembrane transport
JMB28_RS12660	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
JMB28_RS12665	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
JMB28_RS12670	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
JMB28_RS12675	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
JMB28_RS12680	COG3257	ureidoglycine aminohydrolase activity
JMB28_RS12685	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
JMB28_RS12695	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
JMB28_RS12700	COG0406	alpha-ribazole phosphatase activity
JMB28_RS12710	COG1595	DNA-templated transcription, initiation
JMB28_RS12720	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
JMB28_RS12730	COG1876	peptidase activity
JMB28_RS12735	COG0753	catalase activity
JMB28_RS12745	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
JMB28_RS12750	COG1953	Uracil, thiamine, allantoin
JMB28_RS12755	COG2508	Transcriptional regulator
JMB28_RS12760	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
JMB28_RS12760	COG0456	acetyltransferase
JMB28_RS12765	COG2814	Major facilitator Superfamily
JMB28_RS12775	COG2814	Major facilitator Superfamily
JMB28_RS12795	COG1301	dicarboxylic acid transport
JMB28_RS12835	COG0518	GMP synthase (glutamine-hydrolyzing) activity
JMB28_RS12835	COG0519	Catalyzes the synthesis of GMP from XMP
JMB28_RS12840	COG0516	GMP reductase activity
JMB28_RS12840	COG0517	IMP dehydrogenase activity
JMB28_RS12845	COG2233	PERMEase
JMB28_RS12850	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
JMB28_RS12865	COG5183	chlorophyll binding
JMB28_RS12870	COG1823	symporter activity
JMB28_RS12880	COG0778	Nitroreductase
JMB28_RS12885	COG0753	catalase activity
JMB28_RS12890	COG0450	alkyl hydroperoxide reductase
JMB28_RS12895	COG3634	alkyl hydroperoxide reductase activity
JMB28_RS12930	COG1280	lysine exporter protein (LysE YggA)
JMB28_RS12935	COG2076	Multidrug Resistance protein
JMB28_RS12940	COG2076	Multidrug Resistance protein
JMB28_RS12960	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
JMB28_RS12975	COG4195	phage-related replication protein
JMB28_RS12980	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
JMB28_RS13000	COG2828	Protein conserved in bacteria
JMB28_RS13005	COG0583	DNA-binding transcription factor activity
JMB28_RS13045	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
JMB28_RS13070	COG0360	Binds together with S18 to 16S ribosomal RNA
JMB28_RS13080	COG0012	GTP binding
JMB28_RS13085	COG4481	Protein conserved in bacteria
JMB28_RS13090	COG0668	transmembrane transport
JMB28_RS13095	COG5609	conserved protein (DUF2294)
JMB28_RS13100	COG3002	Belongs to the UPF0753 family
JMB28_RS13105	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
JMB28_RS13115	COG1486	melibiose metabolic process
JMB28_RS13120	COG2211	Major facilitator Superfamily
JMB28_RS13135	COG0706	membrane insertase activity
JMB28_RS13155	COG3181	Tripartite tricarboxylate transporter family receptor
JMB28_RS13160	COG2311	Membrane
JMB28_RS13165	COG1028	Short-chain dehydrogenase reductase Sdr
JMB28_RS13180	COG0577	efflux transmembrane transporter activity
JMB28_RS13185	COG1136	(ABC) transporter
JMB28_RS13195	COG1288	antiporter activity
JMB28_RS13205	COG4978	Transcriptional regulator
JMB28_RS13205	COG0789	Transcriptional regulator
JMB28_RS13225	COG1012	belongs to the aldehyde dehydrogenase family
JMB28_RS13245	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
JMB28_RS13250	COG2814	Major facilitator Superfamily
JMB28_RS13255	COG1473	amidohydrolase
JMB28_RS13260	COG2814	Major facilitator Superfamily
JMB28_RS13265	COG1733	regulation of RNA biosynthetic process
JMB28_RS13270	COG2030	dehydratase
JMB28_RS13275	COG3759	membrane
JMB28_RS13285	COG1131	(ABC) transporter
JMB28_RS13290	COG2814	Major facilitator Superfamily
JMB28_RS13305	COG0772	Belongs to the SEDS family
JMB28_RS13325	COG0529	Catalyzes the synthesis of activated sulfate
JMB28_RS13330	COG2046	Belongs to the sulfate adenylyltransferase family
JMB28_RS13335	COG0730	response to heat
JMB28_RS13340	COG1648	precorrin-2 dehydrogenase activity
JMB28_RS13355	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
JMB28_RS13360	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
JMB28_RS13365	COG0175	sulfate reduction
JMB28_RS13370	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
JMB28_RS13370	COG1017	nitric oxide dioxygenase activity
JMB28_RS13375	COG1475	DNA binding
JMB28_RS13380	COG0626	cystathionine gamma-synthase activity
JMB28_RS13385	COG0626	cystathionine gamma-synthase activity
JMB28_RS13390	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
JMB28_RS13390	COG0646	methionine synthase
JMB28_RS13395	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
JMB28_RS13405	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
JMB28_RS13430	COG0183	Belongs to the thiolase family
JMB28_RS13440	COG1960	acyl-CoA dehydrogenase activity
JMB28_RS13445	COG0318	PFAM AMP-dependent synthetase and ligase
JMB28_RS13455	COG2239	Acts as a magnesium transporter
JMB28_RS13460	COG0803	Belongs to the bacterial solute-binding protein 9 family
JMB28_RS13465	COG1108	ABC-type Mn2 Zn2 transport systems permease components
JMB28_RS13500	COG0596	Alpha beta hydrolase
JMB28_RS13525	COG0561	phosphatase activity
JMB28_RS13530	COG0583	DNA-binding transcription factor activity
JMB28_RS13535	COG1607	acyl-coa hydrolase
JMB28_RS13565	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
JMB28_RS13570	COG1063	alcohol dehydrogenase
JMB28_RS13575	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
JMB28_RS13590	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
JMB28_RS13595	COG1028	Short-chain dehydrogenase reductase Sdr
JMB28_RS13600	COG1309	transcriptional regulator
JMB28_RS13610	COG0531	amino acid
JMB28_RS13615	COG0656	L-ascorbic acid biosynthetic process
JMB28_RS13620	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
JMB28_RS13645	COG0789	Transcriptional regulator
JMB28_RS13650	COG1028	Short-chain dehydrogenase reductase Sdr
JMB28_RS13660	COG1063	alcohol dehydrogenase
JMB28_RS13665	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JMB28_RS13685	COG0517	IMP dehydrogenase activity
JMB28_RS13695	COG0450	alkyl hydroperoxide reductase
JMB28_RS13700	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
JMB28_RS13720	COG2271	Major facilitator Superfamily
JMB28_RS13725	COG1966	Carbon starvation protein
JMB28_RS13735	COG0357	Ribosomal RNA small subunit methyltransferase G
JMB28_RS13740	COG0445	tRNA wobble uridine modification
JMB28_RS13745	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
JMB28_RS13750	COG0594	ribonuclease P activity
JMB28_RS13785	COG0583	DNA-binding transcription factor activity
JMB28_RS13790	COG1607	acyl-coa hydrolase
JMB28_RS13800	COG1063	alcohol dehydrogenase
JMB28_RS13845	COG3942	CHAP domain
JMB28_RS13845	COG1705	Flagellar rod assembly protein muramidase FlgJ
JMB28_RS13855	COG1846	Transcriptional regulator
JMB28_RS13895	COG1063	alcohol dehydrogenase
JMB28_RS13910	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
JMB28_RS13925	COG1846	Transcriptional regulator
JMB28_RS13930	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
JMB28_RS13955	COG1476	TRANSCRIPTIONal
JMB28_RS14000	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
JMB28_RS14010	COG4221	oxidoreductase activity
JMB28_RS14020	COG1942	4-Oxalocrotonate Tautomerase
JMB28_RS14055	COG1028	Short-chain dehydrogenase reductase Sdr
JMB28_RS14080	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
JMB28_RS14175	COG0584	glycerophosphoryl diester phosphodiesterase
JMB28_RS14185	COG1611	Belongs to the LOG family
JMB28_RS14310	COG0789	Transcriptional regulator