locus-tag	class	description
CEQ14_RS00015	COG1686	Belongs to the peptidase S11 family
CEQ14_RS00050	COG0659	secondary active sulfate transmembrane transporter activity
CEQ14_RS00055	COG0589	response to stress
CEQ14_RS00075	COG0583	DNA-binding transcription factor activity
CEQ14_RS00140	COG3104	oligopeptide transport
CEQ14_RS00145	COG1597	lipid kinase activity
CEQ14_RS00155	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CEQ14_RS00160	COG1174	glycine betaine transport
CEQ14_RS00170	COG0514	ATP-dependent DNA helicase (RecQ)
CEQ14_RS00175	COG0488	(ABC) transporter
CEQ14_RS00185	COG1368	sulfuric ester hydrolase activity
CEQ14_RS00195	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
CEQ14_RS00210	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CEQ14_RS00215	COG0512	Glutamine amidotransferase of anthranilate synthase
CEQ14_RS00215	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CEQ14_RS00220	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
CEQ14_RS00225	COG0720	synthase
CEQ14_RS00230	COG0602	queuosine metabolic process
CEQ14_RS00245	COG0463	Glycosyl transferase, family 2
CEQ14_RS00250	COG0656	L-ascorbic acid biosynthetic process
CEQ14_RS00255	COG1253	flavin adenine dinucleotide binding
CEQ14_RS00260	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CEQ14_RS00265	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CEQ14_RS00265	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CEQ14_RS00265	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CEQ14_RS00270	COG1105	Belongs to the carbohydrate kinase PfkB family
CEQ14_RS00275	COG1349	DNA-binding transcription factor activity
CEQ14_RS00280	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CEQ14_RS00285	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CEQ14_RS00315	COG0039	L-malate dehydrogenase activity
CEQ14_RS00320	COG0586	Pfam SNARE associated Golgi protein
CEQ14_RS00330	COG4989	oxidoreductase activity
CEQ14_RS00345	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
CEQ14_RS00350	COG4988	ABC transporter
CEQ14_RS00355	COG1968	undecaprenyl-diphosphatase activity
CEQ14_RS00365	COG1671	Belongs to the UPF0178 family
CEQ14_RS00370	COG1611	Belongs to the LOG family
CEQ14_RS00375	COG1279	arginine transmembrane transporter activity
CEQ14_RS00380	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CEQ14_RS00410	COG2814	Major facilitator Superfamily
CEQ14_RS00415	COG2839	Protein conserved in bacteria
CEQ14_RS00420	COG2814	Major facilitator Superfamily
CEQ14_RS00425	COG0583	DNA-binding transcription factor activity
CEQ14_RS00435	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CEQ14_RS00445	COG0217	transcriptional regulatory protein
CEQ14_RS00465	COG3942	CHAP domain
CEQ14_RS00465	COG1388	LysM domain
CEQ14_RS00470	COG0306	phosphate transporter
CEQ14_RS00475	COG1392	Phosphate transport regulator
CEQ14_RS00480	COG2205	protein histidine kinase activity
CEQ14_RS00485	COG0745	RESPONSE REGULATOR receiver
CEQ14_RS00490	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CEQ14_RS00500	COG0657	acetylesterase activity
CEQ14_RS00505	COG3949	Membrane
CEQ14_RS00515	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
CEQ14_RS00520	COG1461	Dihydroxyacetone kinase
CEQ14_RS00525	COG2376	Dihydroxyacetone kinase
CEQ14_RS00530	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CEQ14_RS00535	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CEQ14_RS00540	COG1120	ATPase activity
CEQ14_RS00545	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CEQ14_RS00550	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CEQ14_RS00555	COG1132	(ABC) transporter
CEQ14_RS00565	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
CEQ14_RS00570	COG1216	Glycosyl transferase, family 2
CEQ14_RS00570	COG1442	glycosyl transferase family 8
CEQ14_RS00575	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
CEQ14_RS00580	COG1682	transport, permease protein
CEQ14_RS00585	COG1134	teichoic acid transport
CEQ14_RS00590	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
CEQ14_RS00605	COG1121	(ABC) transporter
CEQ14_RS00610	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CEQ14_RS00615	COG0803	Belongs to the bacterial solute-binding protein 9 family
CEQ14_RS00625	COG1320	monovalent cation:proton antiporter activity
CEQ14_RS00630	COG2212	antiporter activity
CEQ14_RS00635	COG1863	multisubunit Na H antiporter MnhE subunit
CEQ14_RS00640	COG0651	ATP synthesis coupled electron transport
CEQ14_RS00645	COG1006	Multisubunit Na H antiporter MnhC subunit
CEQ14_RS00650	COG2111	Na H antiporter
CEQ14_RS00655	COG2111	Na H antiporter
CEQ14_RS00655	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CEQ14_RS00695	COG0596	Alpha beta hydrolase
CEQ14_RS00710	COG2267	carboxylic ester hydrolase activity
CEQ14_RS00715	COG0546	phosphoglycolate phosphatase activity
CEQ14_RS00720	COG4139	cobalamin transport
CEQ14_RS00725	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CEQ14_RS00730	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CEQ14_RS00735	COG0018	arginyl-trna synthetase
CEQ14_RS00750	COG1078	dGTPase activity
CEQ14_RS00755	COG0456	acetyltransferase
CEQ14_RS00760	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CEQ14_RS00765	COG0667	Aldo Keto reductase
CEQ14_RS00770	COG4844	belongs to the
CEQ14_RS00790	COG0095	Lipoate-protein ligase
CEQ14_RS00795	COG0280	phosphate acetyltransferase
CEQ14_RS00800	COG3253	May function as heme-dependent peroxidase
CEQ14_RS00820	COG1846	Transcriptional regulator
CEQ14_RS00830	COG2363	Small membrane protein
CEQ14_RS00840	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CEQ14_RS00845	COG0351	phosphomethylpyrimidine kinase
CEQ14_RS00860	COG0534	Mate efflux family protein
CEQ14_RS00885	COG0183	Belongs to the thiolase family
CEQ14_RS00890	COG0318	PFAM AMP-dependent synthetase and ligase
CEQ14_RS00900	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
CEQ14_RS00905	COG0363	glucosamine-6-phosphate deaminase activity
CEQ14_RS00915	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CEQ14_RS00920	COG1469	GTP cyclohydrolase I activity
CEQ14_RS00925	COG1846	Transcriptional regulator
CEQ14_RS00930	COG0431	NADPH-dependent FMN reductase
CEQ14_RS00935	COG0561	phosphatase activity
CEQ14_RS00945	COG1428	Deoxynucleoside kinase
CEQ14_RS00950	COG1428	Deoxynucleoside kinase
CEQ14_RS00960	COG0546	phosphoglycolate phosphatase activity
CEQ14_RS00980	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CEQ14_RS00995	COG2814	Major facilitator Superfamily
CEQ14_RS01000	COG2824	Alkylphosphonate utilization operon protein PhnA
CEQ14_RS01010	COG1113	amino acid transport
CEQ14_RS01015	COG2040	homocysteine
CEQ14_RS01020	COG0833	amino acid
CEQ14_RS01030	COG0010	Belongs to the arginase family
CEQ14_RS01035	COG1914	H( )-stimulated, divalent metal cation uptake system
CEQ14_RS01045	COG1069	ribulokinase activity
CEQ14_RS01050	COG1063	alcohol dehydrogenase
CEQ14_RS01055	COG2814	Major facilitator Superfamily
CEQ14_RS01060	COG1349	DNA-binding transcription factor activity
CEQ14_RS01085	COG0583	DNA-binding transcription factor activity
CEQ14_RS01110	COG0667	Aldo Keto reductase
CEQ14_RS01120	COG3477	response to acidic pH
CEQ14_RS01135	COG1682	transport, permease protein
CEQ14_RS01150	COG1028	Short-chain dehydrogenase reductase Sdr
CEQ14_RS01155	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CEQ14_RS01160	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
CEQ14_RS01165	COG1316	TRANSCRIPTIONal
CEQ14_RS01175	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CEQ14_RS01260	COG1473	amidohydrolase
CEQ14_RS01265	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CEQ14_RS01270	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CEQ14_RS01275	COG0049	tRNA binding
CEQ14_RS01280	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CEQ14_RS01290	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CEQ14_RS01295	COG0085	RNA polymerase activity
CEQ14_RS01300	COG2813	Specifically methylates the guanine in position
CEQ14_RS01305	COG0222	ribosome binding
CEQ14_RS01310	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CEQ14_RS01320	COG0081	regulation of translation
CEQ14_RS01325	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CEQ14_RS01330	COG0250	Participates in transcription elongation, termination and antitermination
CEQ14_RS01340	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CEQ14_RS01355	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CEQ14_RS01360	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
CEQ14_RS01365	COG0215	cysteine-tRNA ligase activity
CEQ14_RS01370	COG1045	serine acetyltransferase
CEQ14_RS01375	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CEQ14_RS01380	COG4956	integral membrane protein (PIN domain superfamily)
CEQ14_RS01385	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
CEQ14_RS01390	COG0542	response to heat
CEQ14_RS01395	COG3869	Catalyzes the specific phosphorylation of arginine residues in
CEQ14_RS01400	COG3880	PFAM UvrB UvrC protein
CEQ14_RS01405	COG4463	regulation of RNA biosynthetic process
CEQ14_RS01410	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CEQ14_RS01415	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
CEQ14_RS01420	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
CEQ14_RS01425	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CEQ14_RS01510	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CEQ14_RS01515	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CEQ14_RS01535	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
CEQ14_RS01540	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CEQ14_RS01555	COG1098	S1 RNA binding domain
CEQ14_RS01565	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
CEQ14_RS01570	COG3956	TIGRFAM MazG family protein
CEQ14_RS01575	COG2244	polysaccharide biosynthetic process
CEQ14_RS01580	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CEQ14_RS01585	COG0193	aminoacyl-tRNA hydrolase activity
CEQ14_RS01590	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
CEQ14_RS01595	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CEQ14_RS01600	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CEQ14_RS01605	COG2088	sporulation resulting in formation of a cellular spore
CEQ14_RS01610	COG0251	oxidation-reduction process
CEQ14_RS01615	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CEQ14_RS01620	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
CEQ14_RS01625	COG4466	Protein conserved in bacteria
CEQ14_RS01630	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CEQ14_RS01635	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
CEQ14_RS01640	COG0084	hydrolase, TatD family'
CEQ14_RS01645	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CEQ14_RS01645	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CEQ14_RS01650	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CEQ14_RS01655	COG2827	Endonuclease containing a URI domain
CEQ14_RS01660	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
CEQ14_RS01665	COG4467	Involved in initiation control of chromosome replication
CEQ14_RS01670	COG1774	PSP1 C-terminal conserved region
CEQ14_RS01675	COG0470	DNA polymerase III
CEQ14_RS01680	COG3870	Protein conserved in bacteria
CEQ14_RS01685	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CEQ14_RS01690	COG1982	Orn Lys Arg decarboxylase major
CEQ14_RS01710	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CEQ14_RS01715	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
CEQ14_RS01720	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CEQ14_RS01735	COG2188	Transcriptional regulator
CEQ14_RS01740	COG0366	Alpha amylase catalytic
CEQ14_RS01745	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CEQ14_RS01745	COG1263	PTS System
CEQ14_RS01755	COG0493	'glutamate synthase
CEQ14_RS01760	COG0067	glutamate synthase
CEQ14_RS01760	COG0069	glutamate synthase activity
CEQ14_RS01760	COG0070	glutamate synthase
CEQ14_RS01765	COG0583	DNA-binding transcription factor activity
CEQ14_RS01780	COG0004	ammonium transporteR
CEQ14_RS01785	COG0494	nUDIX hydrolase
CEQ14_RS01795	COG3942	CHAP domain
CEQ14_RS01795	COG1388	LysM domain
CEQ14_RS01805	COG0129	dihydroxy-acid dehydratase activity
CEQ14_RS01820	COG0733	neurotransmitter:sodium symporter activity
CEQ14_RS01825	COG1114	Component of the transport system for branched-chain amino acids
CEQ14_RS01830	COG5646	InterPro IPR014922
CEQ14_RS01850	COG4195	phage-related replication protein
CEQ14_RS01855	COG2807	transmembrane transport
CEQ14_RS01860	COG0456	acetyltransferase
CEQ14_RS01860	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
CEQ14_RS01865	COG2814	Major facilitator Superfamily
CEQ14_RS01870	COG0583	DNA-binding transcription factor activity
CEQ14_RS01875	COG2814	Major facilitator Superfamily
CEQ14_RS01935	COG0346	lactoylglutathione lyase activity
CEQ14_RS02025	COG0582	viral genome integration into host DNA
CEQ14_RS02030	COG0519	Catalyzes the synthesis of GMP from XMP
CEQ14_RS02030	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CEQ14_RS02035	COG0517	IMP dehydrogenase activity
CEQ14_RS02035	COG0516	GMP reductase activity
CEQ14_RS02040	COG2233	PERMEase
CEQ14_RS02045	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CEQ14_RS02065	COG1823	symporter activity
CEQ14_RS02075	COG0778	Nitroreductase
CEQ14_RS02080	COG3620	sequence-specific DNA binding
CEQ14_RS02085	COG0450	alkyl hydroperoxide reductase
CEQ14_RS02090	COG3634	alkyl hydroperoxide reductase activity
CEQ14_RS02130	COG2076	Multidrug Resistance protein
CEQ14_RS02135	COG2076	Multidrug Resistance protein
CEQ14_RS02145	COG1214	PFAM Peptidase M22, glycoprotease
CEQ14_RS02145	COG0456	acetyltransferase
CEQ14_RS02155	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CEQ14_RS02175	COG4195	phage-related replication protein
CEQ14_RS02180	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CEQ14_RS02190	COG1522	sequence-specific DNA binding
CEQ14_RS02205	COG2808	Putative FMN-binding domain
CEQ14_RS02245	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CEQ14_RS02255	COG0360	Binds together with S18 to 16S ribosomal RNA
CEQ14_RS02265	COG0012	GTP binding
CEQ14_RS02270	COG4481	Protein conserved in bacteria
CEQ14_RS02275	COG0668	transmembrane transport
CEQ14_RS02280	COG5609	conserved protein (DUF2294)
CEQ14_RS02285	COG3002	Belongs to the UPF0753 family
CEQ14_RS02290	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CEQ14_RS02305	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CEQ14_RS02335	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CEQ14_RS02340	COG2814	Major facilitator Superfamily
CEQ14_RS02370	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CEQ14_RS02380	COG0529	Catalyzes the synthesis of activated sulfate
CEQ14_RS02385	COG2046	Belongs to the sulfate adenylyltransferase family
CEQ14_RS02390	COG0730	response to heat
CEQ14_RS02410	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CEQ14_RS02415	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
CEQ14_RS02420	COG0175	sulfate reduction
CEQ14_RS02435	COG1475	DNA binding
CEQ14_RS02440	COG0626	cystathionine gamma-synthase activity
CEQ14_RS02445	COG0626	cystathionine gamma-synthase activity
CEQ14_RS02450	COG0646	methionine synthase
CEQ14_RS02450	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
CEQ14_RS02455	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CEQ14_RS02465	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
CEQ14_RS02490	COG0183	Belongs to the thiolase family
CEQ14_RS02500	COG1960	acyl-CoA dehydrogenase activity
CEQ14_RS02505	COG0318	PFAM AMP-dependent synthetase and ligase
CEQ14_RS02515	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CEQ14_RS02525	COG0561	phosphatase activity
CEQ14_RS02530	COG0531	amino acid
CEQ14_RS02535	COG0656	L-ascorbic acid biosynthetic process
CEQ14_RS02565	COG1966	Carbon starvation protein
CEQ14_RS02570	COG1475	DNA binding
CEQ14_RS02575	COG0357	Ribosomal RNA small subunit methyltransferase G
CEQ14_RS02580	COG0445	tRNA wobble uridine modification
CEQ14_RS02585	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
CEQ14_RS02590	COG0594	ribonuclease P activity
CEQ14_RS02600	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CEQ14_RS02605	COG0592	DNA-directed DNA polymerase activity
CEQ14_RS02610	COG2501	S4 domain
CEQ14_RS02615	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CEQ14_RS02620	COG0187	DNA topoisomerase II activity
CEQ14_RS02630	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CEQ14_RS02635	COG2986	histidine ammonia-lyase
CEQ14_RS02640	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CEQ14_RS02645	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
CEQ14_RS02655	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CEQ14_RS02665	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
CEQ14_RS02670	COG0359	binds to the 23S rRNA
CEQ14_RS02675	COG0305	Participates in initiation and elongation during chromosome replication
CEQ14_RS02680	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CEQ14_RS02685	COG1819	glycosyl
CEQ14_RS02705	COG0477	Major facilitator Superfamily
CEQ14_RS02710	COG0745	RESPONSE REGULATOR receiver
CEQ14_RS02715	COG5002	protein histidine kinase activity
CEQ14_RS02720	COG4863	YycH protein
CEQ14_RS02730	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
CEQ14_RS02735	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
CEQ14_RS02760	COG0737	Belongs to the 5'-nucleotidase family
CEQ14_RS02775	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
CEQ14_RS02780	COG3639	organic phosphonate transmembrane transporter activity
CEQ14_RS02790	COG2826	transposase and inactivated derivatives, IS30 family
CEQ14_RS02850	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
CEQ14_RS02855	COG0732	type I restriction modification DNA specificity domain
CEQ14_RS02860	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
CEQ14_RS02880	COG1388	LysM domain
CEQ14_RS02885	COG0730	response to heat
CEQ14_RS02890	COG1937	Protein conserved in bacteria
CEQ14_RS02895	COG2210	Belongs to the sulfur carrier protein TusA family
CEQ14_RS02900	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CEQ14_RS02910	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CEQ14_RS02915	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CEQ14_RS02930	COG0640	Transcriptional regulator
CEQ14_RS02960	COG1113	amino acid transport
CEQ14_RS02970	COG0753	catalase activity
CEQ14_RS02980	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
CEQ14_RS02990	COG0789	Transcriptional regulator
CEQ14_RS03000	COG0702	epimerase
CEQ14_RS03005	COG2130	NADP-dependent
CEQ14_RS03025	COG0702	epimerase
CEQ14_RS03030	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
CEQ14_RS03065	COG0415	Belongs to the DNA photolyase family
CEQ14_RS03110	COG0789	Transcriptional regulator
CEQ14_RS03115	COG1028	Short-chain dehydrogenase reductase Sdr
CEQ14_RS03120	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CEQ14_RS03125	COG2022	thiamine diphosphate biosynthetic process
CEQ14_RS03135	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CEQ14_RS03145	COG1070	Carbohydrate kinase
CEQ14_RS03185	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CEQ14_RS03195	COG0579	oxidoreductase
CEQ14_RS03200	COG0028	Belongs to the TPP enzyme family
CEQ14_RS03205	COG3527	Alpha-acetolactate decarboxylase
CEQ14_RS03210	COG1620	l-lactate permease
CEQ14_RS03215	COG0583	DNA-binding transcription factor activity
CEQ14_RS03220	COG2814	Major facilitator Superfamily
CEQ14_RS03230	COG1136	(ABC) transporter
CEQ14_RS03240	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CEQ14_RS03285	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CEQ14_RS03290	COG1733	regulation of RNA biosynthetic process
CEQ14_RS03295	COG2207	Transcriptional regulator
CEQ14_RS03300	COG2211	Major facilitator Superfamily
CEQ14_RS03305	COG3250	beta-galactosidase activity
CEQ14_RS03315	COG0463	Glycosyl transferase, family 2
CEQ14_RS03345	COG1028	Short-chain dehydrogenase reductase Sdr
CEQ14_RS03355	COG1388	LysM domain
CEQ14_RS03360	COG1388	LysM domain
CEQ14_RS03365	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CEQ14_RS03380	COG1263	PTS System
CEQ14_RS03380	COG2190	(PTS) system
CEQ14_RS03380	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CEQ14_RS03395	COG1054	Belongs to the UPF0176 family
CEQ14_RS03425	COG1131	(ABC) transporter
CEQ14_RS03435	COG5295	Hep Hag repeat protein
CEQ14_RS03435	COG4932	domain protein
CEQ14_RS03435	COG5295	Hep Hag repeat protein
CEQ14_RS03435	COG4932	domain protein
CEQ14_RS03450	COG1511	domain protein
CEQ14_RS03450	COG1511	domain protein
CEQ14_RS03475	COG1328	CTP reductase activity
CEQ14_RS03485	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
CEQ14_RS03490	COG0346	lactoylglutathione lyase activity
CEQ14_RS03525	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
CEQ14_RS03530	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
CEQ14_RS03535	COG0579	oxidoreductase
CEQ14_RS03575	COG0477	Major facilitator Superfamily
CEQ14_RS03585	COG2814	Major facilitator Superfamily
CEQ14_RS03590	COG0583	DNA-binding transcription factor activity
CEQ14_RS03605	COG0584	glycerophosphoryl diester phosphodiesterase
CEQ14_RS03615	COG3961	Belongs to the TPP enzyme family
CEQ14_RS03625	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
CEQ14_RS03630	COG1691	(AIR) carboxylase
CEQ14_RS03635	COG1606	tRNA processing
CEQ14_RS03640	COG3875	lactate racemase activity
CEQ14_RS03650	COG3835	regulator
CEQ14_RS03655	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CEQ14_RS03655	COG0574	Belongs to the PEP-utilizing enzyme family
CEQ14_RS03660	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
CEQ14_RS03670	COG1396	sequence-specific DNA binding
CEQ14_RS03675	COG2807	transmembrane transport
CEQ14_RS03685	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CEQ14_RS03690	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CEQ14_RS03695	COG1012	belongs to the aldehyde dehydrogenase family
CEQ14_RS03700	COG0531	amino acid
CEQ14_RS03715	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CEQ14_RS03725	COG1510	regulation of RNA biosynthetic process
CEQ14_RS03730	COG1012	belongs to the aldehyde dehydrogenase family
CEQ14_RS03735	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
CEQ14_RS03740	COG0583	DNA-binding transcription factor activity
CEQ14_RS03745	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CEQ14_RS03755	COG0463	Glycosyl transferase, family 2
CEQ14_RS03755	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
CEQ14_RS03770	COG0778	Nitroreductase
CEQ14_RS03775	COG2843	Capsule synthesis protein
CEQ14_RS03780	COG1957	nucleoside hydrolase
CEQ14_RS03785	COG0477	Major facilitator Superfamily
CEQ14_RS03815	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
CEQ14_RS03820	COG0693	protein deglycase activity
CEQ14_RS03825	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CEQ14_RS03825	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CEQ14_RS03830	COG1063	alcohol dehydrogenase
CEQ14_RS03835	COG0697	spore germination
CEQ14_RS03840	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CEQ14_RS03845	COG1733	regulation of RNA biosynthetic process
CEQ14_RS03850	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
CEQ14_RS03880	COG0583	DNA-binding transcription factor activity
CEQ14_RS03885	COG1607	acyl-coa hydrolase
CEQ14_RS03905	COG1705	Flagellar rod assembly protein muramidase FlgJ
CEQ14_RS03905	COG3942	CHAP domain
CEQ14_RS03930	COG0693	protein deglycase activity
CEQ14_RS03935	COG0702	epimerase
CEQ14_RS03950	COG1028	Short-chain dehydrogenase reductase Sdr
CEQ14_RS03950	COG3321	synthase
CEQ14_RS03950	COG0604	alcohol dehydrogenase
CEQ14_RS03975	COG0531	amino acid
CEQ14_RS03980	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CEQ14_RS03985	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CEQ14_RS03990	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
CEQ14_RS03995	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CEQ14_RS04015	COG0431	NADPH-dependent FMN reductase
CEQ14_RS04020	COG3226	Transcriptional regulator
CEQ14_RS04035	COG1620	l-lactate permease
CEQ14_RS04040	COG2814	Major facilitator Superfamily
CEQ14_RS04055	COG0363	glucosamine-6-phosphate deaminase activity
CEQ14_RS04070	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CEQ14_RS04080	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CEQ14_RS04085	COG1447	Phosphotransferase system cellobiose-specific component IIA
CEQ14_RS04090	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CEQ14_RS04095	COG0765	amino acid transport
CEQ14_RS04100	COG1126	abc transporter atp-binding protein
CEQ14_RS04115	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CEQ14_RS04125	COG1464	Belongs to the NlpA lipoprotein family
CEQ14_RS04130	COG0039	L-malate dehydrogenase activity
CEQ14_RS04135	COG1940	carbohydrate kinase activity
CEQ14_RS04145	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CEQ14_RS04150	COG0626	cystathionine gamma-synthase activity
CEQ14_RS04175	COG0829	nickel cation binding
CEQ14_RS04180	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
CEQ14_RS04185	COG0830	nickel cation binding
CEQ14_RS04190	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
CEQ14_RS04195	COG0804	urea catabolic process
CEQ14_RS04200	COG0832	Belongs to the urease beta subunit family
CEQ14_RS04205	COG0831	urea catabolic process
CEQ14_RS04210	COG4413	Urea transporter
CEQ14_RS04215	COG0747	negative chemotaxis
CEQ14_RS04240	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CEQ14_RS04250	COG0531	amino acid
CEQ14_RS04260	COG0561	phosphatase activity
CEQ14_RS04270	COG0167	dihydroorotate dehydrogenase activity
CEQ14_RS04275	COG3001	Fructosamine kinase
CEQ14_RS04305	COG1113	amino acid transport
CEQ14_RS04325	COG3189	MarR family transcriptional regulator
CEQ14_RS04340	COG0741	lytic transglycosylase activity
CEQ14_RS04345	COG0436	Aminotransferase
CEQ14_RS04355	COG2608	mercury ion transmembrane transporter activity
CEQ14_RS04360	COG2217	Heavy metal translocating P-type atpase
CEQ14_RS04365	COG0659	secondary active sulfate transmembrane transporter activity
CEQ14_RS04370	COG1136	(ABC) transporter
CEQ14_RS04375	COG0577	efflux transmembrane transporter activity
CEQ14_RS04380	COG1028	Short-chain dehydrogenase reductase Sdr
CEQ14_RS04395	COG0471	metal ion transport
CEQ14_RS04400	COG5505	Protein of unknown function (DUF819)
CEQ14_RS04415	COG4336	lyase activity
CEQ14_RS04425	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
CEQ14_RS04430	COG1012	belongs to the aldehyde dehydrogenase family
CEQ14_RS04440	COG2409	Drug exporters of the RND superfamily
CEQ14_RS04455	COG1473	amidohydrolase
CEQ14_RS04480	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CEQ14_RS04485	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CEQ14_RS04490	COG3425	synthase
CEQ14_RS04505	COG3386	PFAM SMP-30 Gluconolaconase
CEQ14_RS04510	COG3942	CHAP domain
CEQ14_RS04515	COG1757	Na H antiporter
CEQ14_RS04520	COG0583	DNA-binding transcription factor activity
CEQ14_RS04530	COG1346	cytolysis
CEQ14_RS04535	COG0028	Belongs to the TPP enzyme family
CEQ14_RS04540	COG1288	antiporter activity
CEQ14_RS04545	COG2190	(PTS) system
CEQ14_RS04545	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CEQ14_RS04545	COG1263	PTS System
CEQ14_RS04565	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CEQ14_RS04590	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CEQ14_RS04600	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CEQ14_RS04610	COG2843	Capsule synthesis protein
CEQ14_RS04625	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
CEQ14_RS04630	COG1063	alcohol dehydrogenase
CEQ14_RS04635	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
CEQ14_RS04655	COG1129	ABC transporter
CEQ14_RS04675	COG1070	Carbohydrate kinase
CEQ14_RS04680	COG1063	alcohol dehydrogenase
CEQ14_RS04695	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CEQ14_RS04705	COG3764	Sortase (surface protein transpeptidase)
CEQ14_RS04710	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
CEQ14_RS04715	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CEQ14_RS04725	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CEQ14_RS04740	COG2249	NAD(P)H dehydrogenase (quinone) activity
CEQ14_RS04745	COG0561	phosphatase activity
CEQ14_RS04750	COG0778	Nitroreductase
CEQ14_RS04755	COG2723	6-phospho-beta-galactosidase activity
CEQ14_RS04760	COG3711	transcriptional antiterminator
CEQ14_RS04765	COG3711	transcriptional antiterminator
CEQ14_RS04770	COG2514	catechol 2,3-dioxygenase activity
CEQ14_RS04780	COG1132	(ABC) transporter
CEQ14_RS04785	COG1132	(ABC) transporter
CEQ14_RS04805	COG1846	Transcriptional regulator
CEQ14_RS04810	COG0346	lactoylglutathione lyase activity
CEQ14_RS04815	COG0346	lactoylglutathione lyase activity
CEQ14_RS04820	COG0400	carboxylic ester hydrolase activity
CEQ14_RS04830	COG0471	metal ion transport
CEQ14_RS04835	COG3949	Membrane
CEQ14_RS04845	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
CEQ14_RS04850	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CEQ14_RS04855	COG0586	Pfam SNARE associated Golgi protein
CEQ14_RS04860	COG2271	Major facilitator Superfamily
CEQ14_RS04870	COG1289	transmembrane transporter activity
CEQ14_RS04885	COG4876	unkown
CEQ14_RS04890	COG2357	RelA SpoT domain protein
CEQ14_RS04900	COG1802	Transcriptional regulator
CEQ14_RS04910	COG2610	gluconate transmembrane transporter activity
CEQ14_RS04920	COG3949	Membrane
CEQ14_RS04940	COG4221	oxidoreductase activity
CEQ14_RS04965	COG0107	imidazoleglycerol-phosphate synthase activity
CEQ14_RS04970	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
CEQ14_RS04975	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CEQ14_RS04980	COG0131	Imidazoleglycerol-phosphate dehydratase
CEQ14_RS04985	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CEQ14_RS04990	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CEQ14_RS04995	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
CEQ14_RS05000	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
CEQ14_RS05005	COG3048	D-serine ammonia-lyase activity
CEQ14_RS05010	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
CEQ14_RS05020	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
CEQ14_RS05025	COG1028	Short-chain dehydrogenase reductase Sdr
CEQ14_RS05030	COG1363	Peptidase, m42
CEQ14_RS05040	COG0069	glutamate synthase activity
CEQ14_RS05050	COG4619	ABC transporter
CEQ14_RS05055	COG0390	transport system, permease component
CEQ14_RS05060	COG2814	Major facilitator Superfamily
CEQ14_RS05065	COG0531	amino acid
CEQ14_RS05080	COG3246	L-lysine catabolic process to acetate
CEQ14_RS05085	COG1250	3-hydroxyacyl-CoA dehydrogenase
CEQ14_RS05100	COG1174	glycine betaine transport
CEQ14_RS05110	COG1174	glycine betaine transport
CEQ14_RS05120	COG1960	acyl-CoA dehydrogenase activity
CEQ14_RS05125	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CEQ14_RS05135	COG1116	anion transmembrane transporter activity
CEQ14_RS05145	COG1346	cytolysis
CEQ14_RS05150	COG1380	Effector of murein hydrolase LrgA
CEQ14_RS05155	COG3279	Response regulator of the LytR AlgR family
CEQ14_RS05160	COG3275	phosphorelay sensor kinase activity
CEQ14_RS05170	COG4187	Peptidase family M20/M25/M40
CEQ14_RS05190	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
CEQ14_RS05205	COG0025	NhaP-type Na H and K H
CEQ14_RS05225	COG2814	Major facilitator Superfamily
CEQ14_RS05235	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CEQ14_RS05240	COG1388	LysM domain
CEQ14_RS05245	COG0588	phosphoglycerate mutase activity
CEQ14_RS05255	COG2814	Major facilitator Superfamily
CEQ14_RS05280	COG0803	Belongs to the bacterial solute-binding protein 9 family
CEQ14_RS05280	COG3443	Belongs to the bacterial solute-binding protein 9 family
CEQ14_RS05285	COG2353	YceI-like domain
CEQ14_RS05310	COG2723	6-phospho-beta-galactosidase activity
CEQ14_RS05315	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CEQ14_RS05315	COG2190	(PTS) system
CEQ14_RS05315	COG1263	PTS System
CEQ14_RS05320	COG2188	Transcriptional regulator
CEQ14_RS05325	COG1959	2 iron, 2 sulfur cluster binding
CEQ14_RS05330	COG2116	formate transmembrane transporter activity
CEQ14_RS05335	COG0454	-acetyltransferase
CEQ14_RS05350	COG0071	Belongs to the small heat shock protein (HSP20) family
CEQ14_RS05360	COG1846	Transcriptional regulator
CEQ14_RS05390	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CEQ14_RS05390	COG1263	PTS System
CEQ14_RS05410	COG1028	Short-chain dehydrogenase reductase Sdr
CEQ14_RS05415	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CEQ14_RS05420	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CEQ14_RS05425	COG1288	antiporter activity
CEQ14_RS05430	COG1349	DNA-binding transcription factor activity
CEQ14_RS05435	COG1063	alcohol dehydrogenase
CEQ14_RS05440	COG2376	Dihydroxyacetone kinase
CEQ14_RS05450	COG0698	ribose 5-phosphate isomerase
CEQ14_RS05460	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CEQ14_RS05465	COG0492	ferredoxin-NADP+ reductase activity
CEQ14_RS05475	COG2814	Major facilitator Superfamily
CEQ14_RS05480	COG0604	alcohol dehydrogenase
CEQ14_RS05495	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
CEQ14_RS05495	COG0463	Glycosyl transferase, family 2
CEQ14_RS05500	COG1620	l-lactate permease
CEQ14_RS05505	COG0438	transferase activity, transferring glycosyl groups
CEQ14_RS05515	COG5002	protein histidine kinase activity
CEQ14_RS05515	COG3850	Histidine kinase
CEQ14_RS05520	COG0745	RESPONSE REGULATOR receiver
CEQ14_RS05525	COG0577	efflux transmembrane transporter activity
CEQ14_RS05530	COG1136	(ABC) transporter
CEQ14_RS05545	COG4640	response to antibiotic
CEQ14_RS05550	COG2814	Major facilitator Superfamily
CEQ14_RS05560	COG1566	PFAM secretion protein HlyD family protein
CEQ14_RS05565	COG2814	Major facilitator Superfamily
CEQ14_RS05590	COG0598	Magnesium transport protein CorA
CEQ14_RS05595	COG1304	FMN binding
CEQ14_RS05615	COG1757	Na H antiporter
CEQ14_RS05620	COG2094	Belongs to the DNA glycosylase MPG family
CEQ14_RS05625	COG3152	Membrane
CEQ14_RS05630	COG1069	ribulokinase activity
CEQ14_RS05635	COG4152	abc transporter atp-binding protein
CEQ14_RS05640	COG1668	transmembrane transport
CEQ14_RS05645	COG2017	converts alpha-aldose to the beta-anomer
CEQ14_RS05650	COG2258	MOSC domain
CEQ14_RS05655	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
CEQ14_RS05660	COG1266	CAAX protease self-immunity
CEQ14_RS05665	COG0010	Belongs to the arginase family
CEQ14_RS05670	COG0583	DNA-binding transcription factor activity
CEQ14_RS05675	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
CEQ14_RS05680	COG1228	amidohydrolase
CEQ14_RS05690	COG1473	amidohydrolase
CEQ14_RS05695	COG1028	Short-chain dehydrogenase reductase Sdr
CEQ14_RS05700	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CEQ14_RS05720	COG2801	Transposase and inactivated derivatives
CEQ14_RS05730	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CEQ14_RS05730	COG1263	PTS System
CEQ14_RS05740	COG0385	Bile acid
CEQ14_RS05745	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CEQ14_RS05770	COG1113	amino acid transport
CEQ14_RS05775	COG1785	Belongs to the alkaline phosphatase family
CEQ14_RS05780	COG1737	Transcriptional regulator
CEQ14_RS05785	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CEQ14_RS05785	COG1263	PTS System
CEQ14_RS05790	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
CEQ14_RS05810	COG0483	inositol monophosphate 1-phosphatase activity
CEQ14_RS05815	COG1316	TRANSCRIPTIONal
CEQ14_RS05820	COG3383	formate dehydrogenase (NAD+) activity
CEQ14_RS05835	COG4193	domain, Protein
CEQ14_RS05845	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CEQ14_RS05850	COG2076	Multidrug Resistance protein
CEQ14_RS05855	COG2076	Multidrug Resistance protein
CEQ14_RS05860	COG3942	CHAP domain
CEQ14_RS05875	COG1757	Na H antiporter
CEQ14_RS05880	COG3942	CHAP domain
CEQ14_RS05910	COG0765	amino acid transport
CEQ14_RS05915	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CEQ14_RS05920	COG1126	abc transporter atp-binding protein
CEQ14_RS05925	COG1960	acyl-CoA dehydrogenase activity
CEQ14_RS05930	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CEQ14_RS05935	COG1268	BioY protein
CEQ14_RS05945	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
CEQ14_RS05950	COG1609	Transcriptional regulator
CEQ14_RS05955	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
CEQ14_RS05960	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CEQ14_RS05965	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
CEQ14_RS05970	COG0725	ABC transporter, periplasmic molybdate-binding protein
CEQ14_RS05975	COG4149	molybdate abc transporter
CEQ14_RS05990	COG1510	regulation of RNA biosynthetic process
CEQ14_RS05995	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CEQ14_RS06000	COG0521	Mo-molybdopterin cofactor biosynthetic process
CEQ14_RS06005	COG0315	cyclic pyranopterin monophosphate synthase activity
CEQ14_RS06015	COG1763	Mo-molybdopterin cofactor biosynthetic process
CEQ14_RS06030	COG0746	molybdenum cofactor guanylyltransferase activity
CEQ14_RS06035	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CEQ14_RS06045	COG2814	Major facilitator Superfamily
CEQ14_RS06065	COG2348	transferase activity, transferring amino-acyl groups
CEQ14_RS06070	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CEQ14_RS06090	COG4975	Glucose uptake
CEQ14_RS06100	COG0551	DNA topoisomerase type I activity
CEQ14_RS06100	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CEQ14_RS06105	COG2252	PERMEase
CEQ14_RS06115	COG0051	transcription antitermination factor activity, RNA binding
CEQ14_RS06120	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CEQ14_RS06125	COG0088	Forms part of the polypeptide exit tunnel
CEQ14_RS06130	COG0089	rRNA binding
CEQ14_RS06135	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CEQ14_RS06140	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CEQ14_RS06145	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CEQ14_RS06150	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CEQ14_RS06155	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CEQ14_RS06160	COG0255	Belongs to the universal ribosomal protein uL29 family
CEQ14_RS06165	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CEQ14_RS06170	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CEQ14_RS06175	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CEQ14_RS06180	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CEQ14_RS06185	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CEQ14_RS06190	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CEQ14_RS06195	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CEQ14_RS06200	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CEQ14_RS06205	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CEQ14_RS06210	COG1841	ribosomal large subunit assembly
CEQ14_RS06215	COG0200	Binds to the 23S rRNA
CEQ14_RS06220	COG0201	protein transport
CEQ14_RS06225	COG0563	adenylate kinase activity
CEQ14_RS06235	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CEQ14_RS06240	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CEQ14_RS06245	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CEQ14_RS06250	COG0202	RNA polymerase activity
CEQ14_RS06255	COG0203	ribosomal protein L17
CEQ14_RS06260	COG1122	ATPase activity
CEQ14_RS06265	COG1122	ATPase activity
CEQ14_RS06275	COG0101	tRNA pseudouridine synthase activity
CEQ14_RS06280	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CEQ14_RS06285	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CEQ14_RS06295	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CEQ14_RS06300	COG2130	NADP-dependent
CEQ14_RS06305	COG0604	alcohol dehydrogenase
CEQ14_RS06310	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CEQ14_RS06325	COG1302	Protein conserved in bacteria
CEQ14_RS06330	COG4264	IucA IucC family
CEQ14_RS06335	COG2814	Major facilitator Superfamily
CEQ14_RS06340	COG4264	IucA IucC family
CEQ14_RS06345	COG3457	Alanine racemase
CEQ14_RS06350	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
CEQ14_RS06355	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CEQ14_RS06360	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CEQ14_RS06365	COG3314	Sporulation integral membrane protein YlbJ
CEQ14_RS06370	COG2329	Antibiotic biosynthesis monooxygenase
CEQ14_RS06380	COG1988	membrane-bound metal-dependent
CEQ14_RS06385	COG4284	Utp--glucose-1-phosphate uridylyltransferase
CEQ14_RS06390	COG1272	protein, Hemolysin III
CEQ14_RS06405	COG0489	protein tyrosine kinase activity
CEQ14_RS06460	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
CEQ14_RS06470	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CEQ14_RS06475	COG0246	Mannitol dehydrogenase
CEQ14_RS06485	COG3711	transcriptional antiterminator
CEQ14_RS06490	COG2213	PTS system mannitol-specific
CEQ14_RS06505	COG1119	ATPase activity
CEQ14_RS06530	COG0640	Transcriptional regulator
CEQ14_RS06535	COG0702	epimerase
CEQ14_RS06540	COG2186	Transcriptional regulator
CEQ14_RS06545	COG1482	cell wall glycoprotein biosynthetic process
CEQ14_RS06555	COG2855	membrane
CEQ14_RS06570	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CEQ14_RS06575	COG0783	Belongs to the Dps family
CEQ14_RS06580	COG0813	purine-nucleoside phosphorylase activity
CEQ14_RS06585	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
CEQ14_RS06590	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
CEQ14_RS06595	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
CEQ14_RS06605	COG1854	S-ribosylhomocysteine lyase activity
CEQ14_RS06625	COG5146	pantothenate kinase activity
CEQ14_RS06630	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CEQ14_RS06635	COG3343	RNA polymerase activity
CEQ14_RS06640	COG0504	CTP synthase activity
CEQ14_RS06645	COG0191	fructose-bisphosphate aldolase activity
CEQ14_RS06650	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CEQ14_RS06660	COG1012	belongs to the aldehyde dehydrogenase family
CEQ14_RS06665	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CEQ14_RS06670	COG0254	rRNA binding
CEQ14_RS06675	COG1435	thymidine kinase activity
CEQ14_RS06680	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CEQ14_RS06685	COG2890	protein-(glutamine-N5) methyltransferase activity
CEQ14_RS06690	COG0009	L-threonylcarbamoyladenylate synthase
CEQ14_RS06695	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CEQ14_RS06700	COG4475	Protein of unknown function (DUF436)
CEQ14_RS06705	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CEQ14_RS06710	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CEQ14_RS06715	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CEQ14_RS06725	COG0356	it plays a direct role in the translocation of protons across the membrane
CEQ14_RS06730	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CEQ14_RS06735	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CEQ14_RS06740	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CEQ14_RS06745	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CEQ14_RS06750	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CEQ14_RS06755	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CEQ14_RS06760	COG0355	proton-transporting ATP synthase activity, rotational mechanism
CEQ14_RS06770	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CEQ14_RS06775	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CEQ14_RS06785	COG0629	single-stranded DNA binding
CEQ14_RS06790	COG1388	LysM domain
CEQ14_RS06795	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
CEQ14_RS06805	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
CEQ14_RS06810	COG0352	thiamine-phosphate diphosphorylase activity
CEQ14_RS06815	COG0706	membrane insertase activity
CEQ14_RS06820	COG1418	mRNA catabolic process
CEQ14_RS06830	COG1937	Protein conserved in bacteria
CEQ14_RS06845	COG0772	Belongs to the SEDS family
CEQ14_RS06850	COG1181	Belongs to the D-alanine--D-alanine ligase family
CEQ14_RS06855	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CEQ14_RS06860	COG0513	Belongs to the DEAD box helicase family
CEQ14_RS06870	COG3428	Bacterial PH domain
CEQ14_RS06875	COG3402	PFAM membrane-flanked domain
CEQ14_RS06880	COG0736	holo-[acyl-carrier-protein] synthase activity
CEQ14_RS06885	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CEQ14_RS06895	COG2337	Toxic component of a toxin-antitoxin (TA) module
CEQ14_RS06900	COG2208	phosphoserine phosphatase activity
CEQ14_RS06915	COG1191	sigma factor activity
CEQ14_RS06920	COG2183	response to ionizing radiation
CEQ14_RS06925	COG3091	SprT-like family
CEQ14_RS06960	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CEQ14_RS06965	COG0066	3-isopropylmalate dehydratase activity
CEQ14_RS06970	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CEQ14_RS06975	COG0473	3-isopropylmalate dehydrogenase activity
CEQ14_RS06980	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CEQ14_RS06985	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
CEQ14_RS06990	COG0440	acetolactate synthase activity
CEQ14_RS06995	COG0028	Belongs to the TPP enzyme family
CEQ14_RS07000	COG0129	dihydroxy-acid dehydratase activity
CEQ14_RS07005	COG0802	atpase or kinase
CEQ14_RS07010	COG1214	PFAM Peptidase M22, glycoprotease
CEQ14_RS07015	COG0456	acetyltransferase
CEQ14_RS07020	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CEQ14_RS07030	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CEQ14_RS07035	COG0488	(ABC) transporter
CEQ14_RS07040	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
CEQ14_RS07045	COG2391	methyltransferase activity
CEQ14_RS07050	COG0425	Belongs to the sulfur carrier protein TusA family
CEQ14_RS07055	COG1609	Transcriptional regulator
CEQ14_RS07060	COG1621	beta-fructofuranosidase activity
CEQ14_RS07065	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CEQ14_RS07070	COG3279	Response regulator of the LytR AlgR family
CEQ14_RS07075	COG3290	protein histidine kinase activity
CEQ14_RS07085	COG4512	PFAM Accessory gene regulator B
CEQ14_RS07090	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CEQ14_RS07110	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CEQ14_RS07115	COG0459	protein refolding
CEQ14_RS07120	COG0582	viral genome integration into host DNA
CEQ14_RS07270	COG1725	Transcriptional regulator
CEQ14_RS07285	COG1131	(ABC) transporter
CEQ14_RS07330	COG2706	6-phosphogluconolactonase activity
CEQ14_RS07340	COG1012	belongs to the aldehyde dehydrogenase family
CEQ14_RS07345	COG1227	inorganic diphosphatase activity
CEQ14_RS07350	COG1335	isochorismatase
CEQ14_RS07360	COG0471	metal ion transport
CEQ14_RS07365	COG0077	Prephenate dehydratase
CEQ14_RS07375	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CEQ14_RS07380	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CEQ14_RS07385	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
CEQ14_RS07395	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CEQ14_RS07400	COG4496	protein, YerC YecD
CEQ14_RS07410	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
CEQ14_RS07420	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CEQ14_RS07425	COG4851	CamS sex pheromone cAM373 precursor
CEQ14_RS07430	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CEQ14_RS07435	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CEQ14_RS07440	COG0154	amidase activity
CEQ14_RS07445	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CEQ14_RS07450	COG1597	lipid kinase activity
CEQ14_RS07455	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CEQ14_RS07465	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CEQ14_RS07475	COG1528	Iron-storage protein
CEQ14_RS07500	COG2801	Transposase and inactivated derivatives
CEQ14_RS07505	COG4129	membrane
CEQ14_RS07510	COG0024	Methionine aminopeptidase
CEQ14_RS07525	COG4585	Histidine kinase
CEQ14_RS07530	COG2197	response regulator
CEQ14_RS07535	COG1295	ribonuclease BN
CEQ14_RS07545	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CEQ14_RS07550	COG4840	Belongs to the UPF0435 family
CEQ14_RS07555	COG2309	aminopeptidase activity
CEQ14_RS07560	COG1607	acyl-coa hydrolase
CEQ14_RS07565	COG0535	radical SAM domain protein
CEQ14_RS07575	COG0693	protein deglycase activity
CEQ14_RS07580	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CEQ14_RS07585	COG2137	regulation of response to DNA damage stimulus
CEQ14_RS07595	COG1134	teichoic acid transport
CEQ14_RS07605	COG1988	membrane-bound metal-dependent
CEQ14_RS07615	COG3557	Belongs to the UPF0374 family
CEQ14_RS07625	COG4129	membrane
CEQ14_RS07630	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
CEQ14_RS07635	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CEQ14_RS07640	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CEQ14_RS07645	COG0735	belongs to the Fur family
CEQ14_RS07790	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
CEQ14_RS07805	COG0765	amino acid transport
CEQ14_RS07810	COG1126	abc transporter atp-binding protein
CEQ14_RS07815	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CEQ14_RS07825	COG0363	glucosamine-6-phosphate deaminase activity
CEQ14_RS07840	COG0114	fumarate hydratase activity
CEQ14_RS07845	COG0564	pseudouridine synthase activity
CEQ14_RS07850	COG4585	Histidine kinase
CEQ14_RS07850	COG2203	Gaf domain
CEQ14_RS07855	COG2197	response regulator
CEQ14_RS07870	COG1682	transport, permease protein
CEQ14_RS07875	COG0788	formyltetrahydrofolate deformylase activity
CEQ14_RS07885	COG4399	Belongs to the UPF0754 family
CEQ14_RS07890	COG3679	Belongs to the UPF0342 family
CEQ14_RS07895	COG0420	3'-5' exonuclease activity
CEQ14_RS07900	COG4717	serine-type aminopeptidase activity
CEQ14_RS07905	COG3481	metal-dependent phosphohydrolase, HD sub domain
CEQ14_RS07910	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CEQ14_RS07925	COG0537	adenosine 5'-monophosphoramidase activity
CEQ14_RS07930	COG1131	(ABC) transporter
CEQ14_RS07935	COG4473	ABC transporter
CEQ14_RS07945	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
CEQ14_RS07950	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
CEQ14_RS07955	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
CEQ14_RS07960	COG3545	Serine hydrolase
CEQ14_RS08010	COG0318	PFAM AMP-dependent synthetase and ligase
CEQ14_RS08020	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
CEQ14_RS08030	COG1506	peptidase
CEQ14_RS08035	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
CEQ14_RS08040	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CEQ14_RS08050	COG0656	L-ascorbic acid biosynthetic process
CEQ14_RS08055	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CEQ14_RS08060	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CEQ14_RS08070	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CEQ14_RS08100	COG4193	domain, Protein
CEQ14_RS08100	COG3266	domain, Protein
CEQ14_RS08100	COG5632	N-Acetylmuramoyl-L-alanine amidase
CEQ14_RS08120	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CEQ14_RS08120	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CEQ14_RS08125	COG0307	riboflavin synthase, alpha
CEQ14_RS08130	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CEQ14_RS08130	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CEQ14_RS08135	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
CEQ14_RS08145	COG2267	carboxylic ester hydrolase activity
CEQ14_RS08150	COG0039	L-malate dehydrogenase activity
CEQ14_RS08160	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
CEQ14_RS08165	COG1242	4 iron, 4 sulfur cluster binding
CEQ14_RS08170	COG2814	Major facilitator Superfamily
CEQ14_RS08175	COG0495	leucyl-tRNA aminoacylation
CEQ14_RS08185	COG2081	HI0933 family
CEQ14_RS08190	COG2244	polysaccharide biosynthetic process
CEQ14_RS08195	COG1187	pseudouridine synthase activity
CEQ14_RS08205	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CEQ14_RS08210	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CEQ14_RS08215	COG0510	thiamine kinase activity
CEQ14_RS08220	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CEQ14_RS08225	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CEQ14_RS08230	COG5584	Small secreted protein
CEQ14_RS08235	COG1363	Peptidase, m42
CEQ14_RS08240	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CEQ14_RS08245	COG4848	Belongs to the UPF0354 family
CEQ14_RS08250	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CEQ14_RS08255	COG1674	ftsk spoiiie
CEQ14_RS08260	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CEQ14_RS08265	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
CEQ14_RS08275	COG1605	Chorismate mutase
CEQ14_RS08275	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
CEQ14_RS08280	COG1609	Transcriptional regulator
CEQ14_RS08285	COG0123	including yeast histone deacetylase and acetoin utilization protein
CEQ14_RS08290	COG0454	-acetyltransferase
CEQ14_RS08295	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CEQ14_RS08300	COG2759	Belongs to the formate--tetrahydrofolate ligase family
CEQ14_RS08305	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CEQ14_RS08310	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CEQ14_RS08315	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CEQ14_RS08320	COG0204	Acyl-transferase
CEQ14_RS08335	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CEQ14_RS08345	COG1764	response to oxidative stress
CEQ14_RS08350	COG0584	glycerophosphoryl diester phosphodiesterase
CEQ14_RS08360	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CEQ14_RS08370	COG1956	GAF domain-containing protein
CEQ14_RS08375	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
CEQ14_RS08380	COG1104	cysteine desulfurase activity
CEQ14_RS08385	COG0301	tRNA thio-modification
CEQ14_RS08395	COG0616	signal peptide processing
CEQ14_RS08400	COG1714	RDD family
CEQ14_RS08405	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
CEQ14_RS08410	COG0827	DNA restriction-modification system
CEQ14_RS08415	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CEQ14_RS08425	COG0589	response to stress
CEQ14_RS08430	COG0686	Belongs to the AlaDH PNT family
CEQ14_RS08435	COG3142	Participates in the control of copper homeostasis
CEQ14_RS08440	COG0006	proline dipeptidase activity
CEQ14_RS08445	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
CEQ14_RS08455	COG4109	DRTGG domain
CEQ14_RS08460	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
CEQ14_RS08465	COG0587	DNA-directed DNA polymerase activity
CEQ14_RS08470	COG0281	malic enzyme
CEQ14_RS08475	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
CEQ14_RS08480	COG0825	malonyl-CoA metabolic process
CEQ14_RS08485	COG0205	6-phosphofructokinase activity
CEQ14_RS08490	COG0469	pyruvate kinase activity
CEQ14_RS08495	COG1113	amino acid transport
CEQ14_RS08500	COG0372	Belongs to the citrate synthase family
CEQ14_RS08505	COG0538	isocitrate dehydrogenase activity
CEQ14_RS08510	COG0745	RESPONSE REGULATOR receiver
CEQ14_RS08515	COG5002	protein histidine kinase activity
CEQ14_RS08520	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CEQ14_RS08520	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CEQ14_RS08525	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CEQ14_RS08530	COG0237	dephospho-CoA kinase activity
CEQ14_RS08535	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CEQ14_RS08540	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CEQ14_RS08550	COG1484	DNA-dependent DNA replication
CEQ14_RS08555	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CEQ14_RS08560	COG0833	amino acid
CEQ14_RS08565	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CEQ14_RS08570	COG0291	Belongs to the bacterial ribosomal protein bL35 family
CEQ14_RS08575	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CEQ14_RS08580	COG4112	unkown
CEQ14_RS08590	COG0544	peptidyl-prolyl cis-trans isomerase activity
CEQ14_RS08595	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CEQ14_RS08600	COG0218	Necessary for normal cell division and for the maintenance of normal septation
CEQ14_RS08605	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
CEQ14_RS08610	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CEQ14_RS08615	COG0181	hydroxymethylbilane synthase activity
CEQ14_RS08625	COG0113	porphobilinogen synthase activity
CEQ14_RS08630	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
CEQ14_RS08645	COG2818	Glycosylase
CEQ14_RS08650	COG0525	valine-tRNA ligase activity
CEQ14_RS08655	COG0285	dihydrofolate synthase activity
CEQ14_RS08665	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
CEQ14_RS08670	COG2003	Belongs to the UPF0758 family
CEQ14_RS08700	COG0261	This protein binds to 23S rRNA in the presence of protein L20
CEQ14_RS08705	COG2868	ribosomal protein
CEQ14_RS08710	COG0211	Belongs to the bacterial ribosomal protein bL27 family
CEQ14_RS08715	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CEQ14_RS08720	COG4492	Belongs to the UPF0735 family
CEQ14_RS08725	COG0632	four-way junction helicase activity
CEQ14_RS08730	COG2255	four-way junction helicase activity
CEQ14_RS08735	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
CEQ14_RS08740	COG0343	queuine tRNA-ribosyltransferase activity
CEQ14_RS08745	COG1862	Preprotein translocase
CEQ14_RS08750	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CEQ14_RS08750	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CEQ14_RS08755	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
CEQ14_RS08755	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CEQ14_RS08760	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CEQ14_RS08770	COG1490	D-aminoacyl-tRNA deacylase activity
CEQ14_RS08775	COG0860	N-Acetylmuramoyl-L-alanine amidase
CEQ14_RS08780	COG0124	histidyl-tRNA synthetase
CEQ14_RS08785	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CEQ14_RS08795	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CEQ14_RS08800	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CEQ14_RS08805	COG1959	2 iron, 2 sulfur cluster binding
CEQ14_RS08810	COG3237	CsbD-like
CEQ14_RS08815	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CEQ14_RS08820	COG1132	(ABC) transporter
CEQ14_RS08830	COG0488	(ABC) transporter
CEQ14_RS08835	COG1104	cysteine desulfurase activity
CEQ14_RS08840	COG0482	sulfurtransferase activity
CEQ14_RS08850	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CEQ14_RS08855	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CEQ14_RS08860	COG4472	Bacterial protein of unknown function (DUF965)
CEQ14_RS08865	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CEQ14_RS08870	COG3906	Belongs to the UPF0473 family
CEQ14_RS08875	COG4122	O-methyltransferase activity
CEQ14_RS08880	COG0826	peptidase U32
CEQ14_RS08885	COG0826	peptidase U32
CEQ14_RS08890	COG0572	uridine kinase
CEQ14_RS08895	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CEQ14_RS08900	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
CEQ14_RS08905	COG1984	allophanate hydrolase subunit 2
CEQ14_RS08915	COG0439	Biotin carboxylase
CEQ14_RS08920	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
CEQ14_RS08925	COG1914	H( )-stimulated, divalent metal cation uptake system
CEQ14_RS08930	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CEQ14_RS08935	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
CEQ14_RS08940	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
CEQ14_RS08945	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CEQ14_RS08950	COG1534	Rna-binding protein
CEQ14_RS08955	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CEQ14_RS08960	COG1713	HD superfamily hydrolase involved in NAD metabolism
CEQ14_RS08965	COG0799	negative regulation of ribosome biogenesis
CEQ14_RS08970	COG2226	methyltransferase
CEQ14_RS08975	COG1555	photosystem II stabilization
CEQ14_RS08975	COG1596	polysaccharide export
CEQ14_RS08980	COG2131	deaminase
CEQ14_RS08985	COG2333	competence protein COMEC
CEQ14_RS08985	COG0658	competence protein
CEQ14_RS08990	COG1466	dna polymerase III delta subunit
CEQ14_RS08995	COG0268	Binds directly to 16S ribosomal RNA
CEQ14_RS09000	COG0481	GTPase activity
CEQ14_RS09005	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CEQ14_RS09010	COG1420	regulation of RNA biosynthetic process
CEQ14_RS09015	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CEQ14_RS09020	COG0443	Heat shock 70 kDa protein
CEQ14_RS09025	COG0484	heat shock protein binding
CEQ14_RS09030	COG2264	protein methyltransferase activity
CEQ14_RS09035	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CEQ14_RS09040	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CEQ14_RS09045	COG1030	water channel activity
CEQ14_RS09050	COG4864	UPF0365 protein
CEQ14_RS09060	COG1702	phosphate starvation-inducible protein PhoH
CEQ14_RS09065	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CEQ14_RS09075	COG0295	cytidine deaminase activity
CEQ14_RS09080	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CEQ14_RS09085	COG1381	Involved in DNA repair and RecF pathway recombination
CEQ14_RS09090	COG0423	glycine-tRNA ligase activity
CEQ14_RS09095	COG0517	IMP dehydrogenase activity
CEQ14_RS09100	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
CEQ14_RS09110	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CEQ14_RS09115	COG2384	SAM-dependent methyltransferase
CEQ14_RS09120	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CEQ14_RS09125	COG0513	Belongs to the DEAD box helicase family
CEQ14_RS09130	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
CEQ14_RS09135	COG1121	(ABC) transporter
CEQ14_RS09140	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CEQ14_RS09150	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CEQ14_RS09155	COG0768	penicillin binding
CEQ14_RS09160	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CEQ14_RS09165	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CEQ14_RS09170	COG0705	Rhomboid family
CEQ14_RS09170	COG0457	Tetratricopeptide repeat
CEQ14_RS09175	COG4483	Protein conserved in bacteria
CEQ14_RS09180	COG1940	carbohydrate kinase activity
CEQ14_RS09185	COG0011	TIGRFAM Protein of
CEQ14_RS09190	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CEQ14_RS09195	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CEQ14_RS09200	COG1459	type II secretion system
CEQ14_RS09205	COG4537	Required for transformation and DNA binding
CEQ14_RS09230	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CEQ14_RS09235	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CEQ14_RS09240	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CEQ14_RS09245	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CEQ14_RS09250	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CEQ14_RS09255	COG0095	Lipoate-protein ligase
CEQ14_RS09270	COG0006	proline dipeptidase activity
CEQ14_RS09275	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CEQ14_RS09280	COG0511	ligase activity, forming carbon-carbon bonds
CEQ14_RS09285	COG0439	Biotin carboxylase
CEQ14_RS09290	COG1302	Protein conserved in bacteria
CEQ14_RS09295	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CEQ14_RS09300	COG1570	exodeoxyribonuclease VII activity
CEQ14_RS09305	COG1722	exodeoxyribonuclease VII activity
CEQ14_RS09320	COG1438	arginine binding
CEQ14_RS09325	COG0497	DNA recombination
CEQ14_RS09335	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CEQ14_RS09340	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CEQ14_RS09345	COG0022	dehydrogenase e1 component
CEQ14_RS09350	COG0508	dehydrogenase complex catalyzes the overall conversion of
CEQ14_RS09360	COG4129	membrane
CEQ14_RS09365	COG2195	Cleaves the N-terminal amino acid of tripeptides
CEQ14_RS09375	COG1609	Transcriptional regulator
CEQ14_RS09380	COG0366	Alpha amylase catalytic
CEQ14_RS09390	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CEQ14_RS09395	COG1234	tRNA 3'-trailer cleavage
CEQ14_RS09400	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CEQ14_RS09410	COG0667	Aldo Keto reductase
CEQ14_RS09415	COG0494	nUDIX hydrolase
CEQ14_RS09420	COG0735	belongs to the Fur family
CEQ14_RS09425	COG4974	Belongs to the 'phage' integrase family
CEQ14_RS09435	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
CEQ14_RS09440	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CEQ14_RS09445	COG1187	pseudouridine synthase activity
CEQ14_RS09450	COG0745	RESPONSE REGULATOR receiver
CEQ14_RS09465	COG1141	Ferredoxin
CEQ14_RS09475	COG0514	ATP-dependent DNA helicase (RecQ)
CEQ14_RS09480	COG1388	LysM domain
CEQ14_RS09485	COG0492	ferredoxin-NADP+ reductase activity
CEQ14_RS09490	COG0252	asparaginase activity
CEQ14_RS09495	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
CEQ14_RS09500	COG0539	negative regulation of cytoplasmic translation
CEQ14_RS09505	COG1160	GTP binding
CEQ14_RS09510	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CEQ14_RS09525	COG2226	methyltransferase
CEQ14_RS09530	COG0142	geranyltranstransferase activity
CEQ14_RS09535	COG0105	UTP biosynthetic process
CEQ14_RS09540	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CEQ14_RS09545	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CEQ14_RS09550	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CEQ14_RS09565	COG4347	Protein of unknown function (DUF1405)
CEQ14_RS09570	COG2738	Putative neutral zinc metallopeptidase
CEQ14_RS09575	COG1694	Mazg nucleotide pyrophosphohydrolase
CEQ14_RS09580	COG0438	transferase activity, transferring glycosyl groups
CEQ14_RS09585	COG0617	tRNA 3'-terminal CCA addition
CEQ14_RS09590	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
CEQ14_RS09590	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
CEQ14_RS09595	COG1199	ATP-dependent helicase activity
CEQ14_RS09595	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CEQ14_RS09600	COG0017	Asparaginyl-tRNA synthetase
CEQ14_RS09605	COG3935	DnaD domain protein
CEQ14_RS09610	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CEQ14_RS09620	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CEQ14_RS09620	COG4499	WXG100 protein secretion system (Wss), protein YukC
CEQ14_RS09625	COG3331	DNA recombination
CEQ14_RS09635	COG4474	Belongs to the UPF0398 family
CEQ14_RS09640	COG3599	regulation of cell shape
CEQ14_RS09650	COG0116	Belongs to the methyltransferase superfamily
CEQ14_RS09655	COG2962	Rard protein
CEQ14_RS09670	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
CEQ14_RS09675	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CEQ14_RS09680	COG0328	RNA-DNA hybrid ribonuclease activity
CEQ14_RS09685	COG3545	Serine hydrolase
CEQ14_RS09690	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
CEQ14_RS09700	COG1413	lyase activity
CEQ14_RS09705	COG1413	lyase activity
CEQ14_RS09715	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
CEQ14_RS09735	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CEQ14_RS09745	COG4479	Belongs to the UPF0346 family
CEQ14_RS09750	COG0793	Belongs to the peptidase S41A family
CEQ14_RS09760	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CEQ14_RS09765	COG0671	phosphoesterase, PA-phosphatase related
CEQ14_RS09770	COG0745	RESPONSE REGULATOR receiver
CEQ14_RS09775	COG5002	protein histidine kinase activity
CEQ14_RS09780	COG0567	Dehydrogenase, E1 component
CEQ14_RS09785	COG0508	dehydrogenase complex catalyzes the overall conversion of
CEQ14_RS09825	COG0673	inositol 2-dehydrogenase activity
CEQ14_RS09830	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CEQ14_RS09835	COG1121	(ABC) transporter
CEQ14_RS09860	COG0714	Associated with various cellular activities
CEQ14_RS09865	COG4548	von Willebrand factor, type A
CEQ14_RS09870	COG1114	Component of the transport system for branched-chain amino acids
CEQ14_RS09875	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CEQ14_RS09880	COG3853	Toxic anion resistance protein (TelA)
CEQ14_RS09890	COG1254	Belongs to the acylphosphatase family
CEQ14_RS09900	COG1278	Cold shock
CEQ14_RS09915	COG1473	amidohydrolase
CEQ14_RS09920	COG2171	N-acyltransferase activity
CEQ14_RS09925	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
CEQ14_RS09930	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CEQ14_RS09935	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CEQ14_RS09940	COG0527	aspartate kinase activity
CEQ14_RS09950	COG0488	(ABC) transporter
CEQ14_RS09955	COG2996	Protein conserved in bacteria
CEQ14_RS09960	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CEQ14_RS09965	COG0573	inorganic phosphate transmembrane transporter activity
CEQ14_RS09970	COG0581	inorganic phosphate transmembrane transporter activity
CEQ14_RS09975	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CEQ14_RS09980	COG0704	Plays a role in the regulation of phosphate uptake
CEQ14_RS09985	COG1164	Oligoendopeptidase f
CEQ14_RS09995	COG4607	ABC-type enterochelin transport system periplasmic component
CEQ14_RS10005	COG2348	transferase activity, transferring amino-acyl groups
CEQ14_RS10010	COG2348	transferase activity, transferring amino-acyl groups
CEQ14_RS10020	COG0159	tryptophan synthase activity
CEQ14_RS10025	COG0133	tryptophan synthase activity
CEQ14_RS10030	COG0135	phosphoribosylanthranilate isomerase activity
CEQ14_RS10035	COG0134	indole-3-glycerol-phosphate synthase activity
CEQ14_RS10040	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CEQ14_RS10045	COG0512	Glutamine amidotransferase of anthranilate synthase
CEQ14_RS10050	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CEQ14_RS10060	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CEQ14_RS10070	COG1363	Peptidase, m42
CEQ14_RS10085	COG0287	Prephenate dehydrogenase
CEQ14_RS10090	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CEQ14_RS10095	COG1942	4-Oxalocrotonate Tautomerase
CEQ14_RS10110	COG1879	ABC-type sugar transport system periplasmic component
CEQ14_RS10115	COG1172	Belongs to the binding-protein-dependent transport system permease family
CEQ14_RS10120	COG1129	ABC transporter
CEQ14_RS10125	COG1869	D-ribose catabolic process
CEQ14_RS10130	COG1609	Transcriptional regulator
CEQ14_RS10135	COG0392	lysyltransferase activity
CEQ14_RS10135	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
CEQ14_RS10140	COG0628	permease
CEQ14_RS10155	COG3711	transcriptional antiterminator
CEQ14_RS10160	COG1115	amino acid carrier protein
CEQ14_RS10165	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CEQ14_RS10175	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
CEQ14_RS10180	COG4841	protein insertion into membrane
CEQ14_RS10185	COG0824	Thioesterase
CEQ14_RS10190	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CEQ14_RS10195	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CEQ14_RS10200	COG1970	mechanosensitive ion channel activity
CEQ14_RS10205	COG0419	ATPase involved in DNA repair
CEQ14_RS10210	COG0420	3'-5' exonuclease activity
CEQ14_RS10215	COG4846	Membrane protein involved in cytochrome C biogenesis
CEQ14_RS10225	COG3763	UPF0154 protein
CEQ14_RS10245	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CEQ14_RS10255	COG0516	GMP reductase activity
CEQ14_RS10260	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CEQ14_RS10265	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CEQ14_RS10270	COG0753	catalase activity
CEQ14_RS10275	COG0833	amino acid
CEQ14_RS10285	COG0561	phosphatase activity
CEQ14_RS10290	COG0083	homoserine kinase activity
CEQ14_RS10295	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
CEQ14_RS10300	COG0460	homoserine dehydrogenase
CEQ14_RS10305	COG0527	aspartate kinase activity
CEQ14_RS10335	COG2197	response regulator
CEQ14_RS10340	COG4585	Histidine kinase
CEQ14_RS10340	COG2203	Gaf domain
CEQ14_RS10345	COG0842	Transport permease protein
CEQ14_RS10350	COG1131	(ABC) transporter
CEQ14_RS10360	COG0174	glutamine synthetase
CEQ14_RS10365	COG0789	Transcriptional regulator
CEQ14_RS10370	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
CEQ14_RS10375	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CEQ14_RS10380	COG0386	Belongs to the glutathione peroxidase family
CEQ14_RS10385	COG1923	regulation of RNA biosynthetic process
CEQ14_RS10390	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CEQ14_RS10400	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CEQ14_RS10405	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CEQ14_RS10410	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CEQ14_RS10425	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CEQ14_RS10430	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CEQ14_RS10440	COG4550	Control of competence regulator ComK, YlbF/YmcA
CEQ14_RS10445	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CEQ14_RS10470	COG1013	pyruvate-flavodoxin oxidoreductase activity
CEQ14_RS10475	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
CEQ14_RS10475	COG0674	pyruvate-flavodoxin oxidoreductase activity
CEQ14_RS10480	COG1692	metallophosphoesterase
CEQ14_RS10490	COG1418	mRNA catabolic process
CEQ14_RS10495	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CEQ14_RS10500	COG1546	Belongs to the CinA family
CEQ14_RS10500	COG1058	Belongs to the CinA family
CEQ14_RS10520	COG0300	oxidoreductase activity
CEQ14_RS10525	COG0612	Peptidase, M16
CEQ14_RS10530	COG0612	Peptidase, M16
CEQ14_RS10535	COG2188	Transcriptional regulator
CEQ14_RS10540	COG1674	ftsk spoiiie
CEQ14_RS10545	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
CEQ14_RS10550	COG1185	polyribonucleotide nucleotidyltransferase activity
CEQ14_RS10555	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CEQ14_RS10560	COG0196	riboflavin kinase activity
CEQ14_RS10565	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CEQ14_RS10570	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CEQ14_RS10585	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CEQ14_RS10590	COG1358	cellular component organization or biogenesis
CEQ14_RS10595	COG2740	Nucleic-acid-binding protein implicated in transcription termination
CEQ14_RS10600	COG0195	Participates in both transcription termination and antitermination
CEQ14_RS10605	COG0779	Required for maturation of 30S ribosomal subunits
CEQ14_RS10610	COG2176	DNA-directed DNA polymerase activity
CEQ14_RS10615	COG0442	prolyl-tRNA aminoacylation
CEQ14_RS10625	COG4589	Belongs to the CDS family
CEQ14_RS10630	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CEQ14_RS10635	COG0233	cytoplasmic translational termination
CEQ14_RS10640	COG0528	UMP kinase activity
CEQ14_RS10645	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CEQ14_RS10650	COG0052	Belongs to the universal ribosomal protein uS2 family
CEQ14_RS10655	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
CEQ14_RS10660	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
CEQ14_RS10665	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
CEQ14_RS10670	COG4974	Belongs to the 'phage' integrase family
CEQ14_RS10675	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
CEQ14_RS10680	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CEQ14_RS10685	COG0758	DNA mediated transformation
CEQ14_RS10695	COG0045	succinate-CoA ligase (ADP-forming) activity
CEQ14_RS10700	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CEQ14_RS10710	COG4485	Bacterial membrane protein, YfhO
CEQ14_RS10720	COG0335	large ribosomal subunit rRNA binding
CEQ14_RS10725	COG0336	Belongs to the RNA methyltransferase TrmD family
CEQ14_RS10730	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CEQ14_RS10735	COG0228	four-way junction DNA binding
CEQ14_RS10740	COG1028	Short-chain dehydrogenase reductase Sdr
CEQ14_RS10745	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CEQ14_RS10750	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CEQ14_RS10755	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
CEQ14_RS10760	COG0552	protein localization to endoplasmic reticulum
CEQ14_RS10765	COG1196	nuclear chromosome segregation
CEQ14_RS10770	COG0571	ribonuclease III activity
CEQ14_RS10775	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CEQ14_RS10790	COG0416	fatty acid biosynthetic process
CEQ14_RS10795	COG1349	DNA-binding transcription factor activity
CEQ14_RS10805	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CEQ14_RS10810	COG1760	l-serine dehydratase
CEQ14_RS10815	COG1760	l-serine dehydratase
CEQ14_RS10820	COG1461	Dihydroxyacetone kinase
CEQ14_RS10825	COG1302	Protein conserved in bacteria
CEQ14_RS10830	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CEQ14_RS10835	COG1564	THIamine pyrophosphokinase
CEQ14_RS10840	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CEQ14_RS10845	COG1162	GTPase activity
CEQ14_RS10855	COG0631	protein serine/threonine phosphatase activity
CEQ14_RS10860	COG0820	rRNA (adenine-C2-)-methyltransferase activity
CEQ14_RS10865	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CEQ14_RS10865	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CEQ14_RS10870	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CEQ14_RS10875	COG0242	peptide deformylase activity
CEQ14_RS10890	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CEQ14_RS10895	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CEQ14_RS10900	COG1758	RNA polymerase activity
CEQ14_RS10905	COG0194	GDP metabolic process
CEQ14_RS10910	COG1293	RNA-binding protein homologous to eukaryotic snRNP
CEQ14_RS10920	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CEQ14_RS10930	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CEQ14_RS10935	COG0284	orotidine-5'-phosphate decarboxylase activity
CEQ14_RS10940	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CEQ14_RS10945	COG0505	Belongs to the CarA family
CEQ14_RS10955	COG0540	Belongs to the ATCase OTCase family
CEQ14_RS10965	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
CEQ14_RS10970	COG0564	pseudouridine synthase activity
CEQ14_RS10975	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CEQ14_RS10985	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CEQ14_RS10990	COG3599	regulation of cell shape
CEQ14_RS11000	COG0762	integral membrane protein
CEQ14_RS11005	COG1799	cell septum assembly
CEQ14_RS11010	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CEQ14_RS11015	COG1496	oxidoreductase activity
CEQ14_RS11020	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CEQ14_RS11025	COG0849	cell division
CEQ14_RS11030	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
CEQ14_RS11035	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CEQ14_RS11040	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CEQ14_RS11045	COG0768	penicillin binding
CEQ14_RS11050	COG4839	cell division protein FtsL
CEQ14_RS11055	COG0275	rRNA processing
CEQ14_RS11060	COG2001	Belongs to the MraZ family
CEQ14_RS11065	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
CEQ14_RS11070	COG0454	-acetyltransferase
CEQ14_RS11075	COG1011	Hydrolase
CEQ14_RS11095	COG2274	protein secretion by the type I secretion system
CEQ14_RS11095	COG3271	cysteine-type peptidase activity
CEQ14_RS11100	COG1280	lysine exporter protein (LysE YggA)
CEQ14_RS11115	COG2801	Transposase and inactivated derivatives
CEQ14_RS11140	COG2261	transglycosylase associated protein
CEQ14_RS11150	COG0582	viral genome integration into host DNA
CEQ14_RS11170	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CEQ14_RS11175	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CEQ14_RS11180	COG1053	succinate dehydrogenase
CEQ14_RS11185	COG2009	succinate dehydrogenase
CEQ14_RS11190	COG0322	excinuclease ABC activity
CEQ14_RS11195	COG3118	belongs to the thioredoxin family
CEQ14_RS11200	COG1193	negative regulation of DNA recombination
CEQ14_RS11205	COG1796	DNA polymerase
CEQ14_RS11205	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
CEQ14_RS11215	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
CEQ14_RS11220	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CEQ14_RS11225	COG0072	phenylalanine-tRNA ligase activity
CEQ14_RS11230	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CEQ14_RS11235	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CEQ14_RS11245	COG0333	Belongs to the bacterial ribosomal protein bL32 family
CEQ14_RS11260	COG1323	Belongs to the UPF0348 family
CEQ14_RS11265	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CEQ14_RS11270	COG0742	ribosomal rna small subunit methyltransferase
CEQ14_RS11285	COG0584	glycerophosphoryl diester phosphodiesterase
CEQ14_RS11290	COG3679	Belongs to the UPF0342 family
CEQ14_RS11310	COG0109	protoheme IX farnesyltransferase activity
CEQ14_RS11315	COG1612	heme a metabolic process
CEQ14_RS11325	COG0772	Belongs to the SEDS family
CEQ14_RS11330	COG4838	Belongs to the UPF0358 family
CEQ14_RS11335	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
CEQ14_RS11340	COG4896	Protein conserved in bacteria
CEQ14_RS11345	COG1217	gtp-binding protein TYPA
CEQ14_RS11355	COG0483	inositol monophosphate 1-phosphatase activity
CEQ14_RS11360	COG4493	Belongs to the UPF0637 family
CEQ14_RS11370	COG1914	H( )-stimulated, divalent metal cation uptake system
CEQ14_RS11385	COG1177	transmembrane transport
CEQ14_RS11390	COG1176	ABC-type spermidine putrescine transport system, permease component I
CEQ14_RS11395	COG3842	ATPase activity
CEQ14_RS11405	COG4476	Belongs to the UPF0223 family
CEQ14_RS11445	COG5503	Protein of unknown function (DUF1447)
CEQ14_RS11450	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
CEQ14_RS11460	COG0569	domain protein
CEQ14_RS11465	COG1294	oxidase, subunit
CEQ14_RS11470	COG1271	oxidase subunit
CEQ14_RS11485	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CEQ14_RS11495	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
CEQ14_RS11510	COG4172	Belongs to the ABC transporter superfamily
CEQ14_RS11515	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CEQ14_RS11520	COG0151	Belongs to the GarS family
CEQ14_RS11525	COG0138	bifunctional purine biosynthesis protein purh
CEQ14_RS11535	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
CEQ14_RS11545	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CEQ14_RS11550	COG0047	phosphoribosylformylglycinamidine synthase activity
CEQ14_RS11555	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CEQ14_RS11560	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
CEQ14_RS11565	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CEQ14_RS11570	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CEQ14_RS11575	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CEQ14_RS11580	COG1017	nitric oxide dioxygenase activity
CEQ14_RS11580	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CEQ14_RS11590	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CEQ14_RS11595	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CEQ14_RS11600	COG1845	cytochrome c oxidase, subunit III
CEQ14_RS11605	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
CEQ14_RS11615	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CEQ14_RS11620	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CEQ14_RS11625	COG1316	TRANSCRIPTIONal
CEQ14_RS11650	COG3594	Acyltransferase
CEQ14_RS11655	COG0436	Aminotransferase
CEQ14_RS11665	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
CEQ14_RS11675	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
CEQ14_RS11680	COG1169	isochorismate synthase
CEQ14_RS11685	COG1575	Belongs to the MenA family. Type 1 subfamily
CEQ14_RS11695	COG2314	TM2 domain
CEQ14_RS11700	COG1764	response to oxidative stress
CEQ14_RS11730	COG4873	Protein conserved in bacteria
CEQ14_RS11740	COG0737	Belongs to the 5'-nucleotidase family
CEQ14_RS11745	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CEQ14_RS11750	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CEQ14_RS11755	COG0861	Integral membrane protein TerC family
CEQ14_RS11760	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
CEQ14_RS11770	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CEQ14_RS11775	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CEQ14_RS11780	COG2814	Major facilitator Superfamily
CEQ14_RS11785	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
CEQ14_RS11790	COG2382	esterase
CEQ14_RS11795	COG1115	amino acid carrier protein
CEQ14_RS11800	COG0628	permease
CEQ14_RS11810	COG0569	domain protein
CEQ14_RS11810	COG0475	glutathione-regulated potassium exporter activity
CEQ14_RS11815	COG2239	Acts as a magnesium transporter
CEQ14_RS11820	COG0564	pseudouridine synthase activity
CEQ14_RS11825	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CEQ14_RS11830	COG2357	RelA SpoT domain protein
CEQ14_RS11840	COG4116	CYTH
CEQ14_RS11845	COG2346	COG2346, Truncated hemoglobins
CEQ14_RS11850	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
CEQ14_RS11855	COG2910	NAD(P)H-binding
CEQ14_RS11860	COG1164	Oligoendopeptidase f
CEQ14_RS11870	COG4862	establishment of competence for transformation
CEQ14_RS11875	COG1393	Belongs to the ArsC family
CEQ14_RS11880	COG0180	Tryptophanyl-tRNA synthetase
CEQ14_RS11885	COG4166	transmembrane transport
CEQ14_RS11890	COG4608	Belongs to the ABC transporter superfamily
CEQ14_RS11895	COG0444	Belongs to the ABC transporter superfamily
CEQ14_RS11900	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CEQ14_RS11925	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CEQ14_RS11935	COG0542	response to heat
CEQ14_RS11950	COG0561	phosphatase activity
CEQ14_RS11955	COG0446	pyridine nucleotide-disulphide oxidoreductase
CEQ14_RS11965	COG0179	Fumarylacetoacetate (FAA) hydrolase
CEQ14_RS11970	COG2311	Membrane
CEQ14_RS11975	COG1074	ATP-dependent DNA helicase activity
CEQ14_RS11980	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
CEQ14_RS11995	COG0398	Pfam SNARE associated Golgi protein
CEQ14_RS12000	COG0166	Belongs to the GPI family
CEQ14_RS12005	COG0137	argininosuccinate synthase activity
CEQ14_RS12010	COG0165	Argininosuccinate lyase
CEQ14_RS12015	COG0584	glycerophosphoryl diester phosphodiesterase
CEQ14_RS12025	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CEQ14_RS12030	COG1902	pentaerythritol trinitrate reductase activity
CEQ14_RS12035	COG1098	S1 RNA binding domain
CEQ14_RS12040	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CEQ14_RS12050	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CEQ14_RS12050	COG2111	Na H antiporter
CEQ14_RS12055	COG2111	Na H antiporter
CEQ14_RS12060	COG1006	Multisubunit Na H antiporter MnhC subunit
CEQ14_RS12065	COG0651	ATP synthesis coupled electron transport
CEQ14_RS12070	COG1863	multisubunit Na H antiporter MnhE subunit
CEQ14_RS12075	COG2212	antiporter activity
CEQ14_RS12080	COG1320	monovalent cation:proton antiporter activity
CEQ14_RS12090	COG2050	protein possibly involved in aromatic compounds catabolism
CEQ14_RS12095	COG2056	Na+-H+ antiporter family
CEQ14_RS12100	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CEQ14_RS12105	COG1252	NADH dehydrogenase
CEQ14_RS12110	COG0316	Belongs to the HesB IscA family
CEQ14_RS12115	COG4844	belongs to the
CEQ14_RS12120	COG1252	NADH dehydrogenase
CEQ14_RS12125	COG4837	Protein of unknown function (DUF1462)
CEQ14_RS12130	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
CEQ14_RS12135	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
CEQ14_RS12140	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CEQ14_RS12145	COG1696	Membrane protein involved in D-alanine export
CEQ14_RS12150	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CEQ14_RS12165	COG0647	UMP catabolic process
CEQ14_RS12170	COG2445	Protein of unknown function DUF86
CEQ14_RS12180	COG4470	Protein conserved in bacteria
CEQ14_RS12185	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
CEQ14_RS12190	COG0737	Belongs to the 5'-nucleotidase family
CEQ14_RS12195	COG0730	response to heat
CEQ14_RS12200	COG1801	Protein of unknown function DUF72
CEQ14_RS12205	COG2070	2-Nitropropane dioxygenase
CEQ14_RS12210	COG1253	flavin adenine dinucleotide binding
CEQ14_RS12220	COG0719	Fe-S assembly protein
CEQ14_RS12225	COG0822	iron-sulfur transferase activity
CEQ14_RS12230	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CEQ14_RS12235	COG0719	Fe-S assembly protein
CEQ14_RS12240	COG0396	ATPase activity
CEQ14_RS12250	COG1253	flavin adenine dinucleotide binding
CEQ14_RS12260	COG1464	Belongs to the NlpA lipoprotein family
CEQ14_RS12265	COG2011	ABC-type metal ion transport system permease component
CEQ14_RS12270	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CEQ14_RS12275	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CEQ14_RS12280	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
CEQ14_RS12285	COG0509	glycine decarboxylation via glycine cleavage system
CEQ14_RS12290	COG1393	Belongs to the ArsC family
CEQ14_RS12295	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CEQ14_RS12300	COG0778	Nitroreductase
CEQ14_RS12305	COG0710	3-dehydroquinate dehydratase activity
CEQ14_RS12310	COG1764	response to oxidative stress
CEQ14_RS12325	COG2851	Citrate transporter
CEQ14_RS12340	COG2314	TM2 domain
CEQ14_RS12430	COG0346	lactoylglutathione lyase activity
CEQ14_RS12490	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
CEQ14_RS12495	COG0557	exoribonuclease II activity
CEQ14_RS12500	COG1647	Serine aminopeptidase, S33
CEQ14_RS12505	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CEQ14_RS12520	COG0148	phosphopyruvate hydratase activity
CEQ14_RS12525	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
CEQ14_RS12530	COG0149	triose-phosphate isomerase activity
CEQ14_RS12535	COG0126	phosphoglycerate kinase activity
CEQ14_RS12565	COG1090	epimerase
CEQ14_RS12575	COG0740	serine-type endopeptidase activity
CEQ14_RS12590	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CEQ14_RS12595	COG1481	regulation of sporulation
CEQ14_RS12600	COG0391	Required for morphogenesis under gluconeogenic growth conditions
CEQ14_RS12605	COG1660	Displays ATPase and GTPase activities
CEQ14_RS12610	COG0492	ferredoxin-NADP+ reductase activity
CEQ14_RS12620	COG0110	maltose O-acetyltransferase activity
CEQ14_RS12625	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CEQ14_RS12630	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
CEQ14_RS12640	COG0556	nucleotide-excision repair
CEQ14_RS12655	COG1388	LysM domain
CEQ14_RS12655	COG3942	CHAP domain
CEQ14_RS12665	COG0653	protein targeting
CEQ14_RS12670	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CEQ14_RS12675	COG1040	competence protein
CEQ14_RS12680	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
CEQ14_RS12690	COG1739	Uncharacterized protein family UPF0029
CEQ14_RS12695	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CEQ14_RS12700	COG2199	diguanylate cyclase activity
CEQ14_RS12715	COG2195	Cleaves the N-terminal amino acid of tripeptides
CEQ14_RS12720	COG1929	Belongs to the glycerate kinase type-1 family
CEQ14_RS12740	COG0812	UDP-N-acetylmuramate dehydrogenase activity
CEQ14_RS12755	COG4607	ABC-type enterochelin transport system periplasmic component
CEQ14_RS12760	COG4604	ABC transporter, ATP-binding protein
CEQ14_RS12765	COG4605	iron ion homeostasis
CEQ14_RS12770	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CEQ14_RS12775	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CEQ14_RS12780	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CEQ14_RS12785	COG1780	Probably involved in ribonucleotide reductase function
CEQ14_RS12795	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
CEQ14_RS12800	COG3104	oligopeptide transport
CEQ14_RS12805	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CEQ14_RS12815	COG1733	regulation of RNA biosynthetic process
CEQ14_RS12835	COG0071	Belongs to the small heat shock protein (HSP20) family
CEQ14_RS12880	COG2249	NAD(P)H dehydrogenase (quinone) activity
CEQ14_RS12895	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
CEQ14_RS12900	COG2169	Transcriptional regulator
CEQ14_RS12905	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CEQ14_RS12920	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
CEQ14_RS12925	COG0166	Belongs to the GPI family
CEQ14_RS12930	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH