locus-tag	class	description
EQ030_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
EQ030_RS00010	COG0592	DNA-directed DNA polymerase activity
EQ030_RS00015	COG2501	S4 domain
EQ030_RS00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
EQ030_RS00025	COG0187	DNA topoisomerase II activity
EQ030_RS00035	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
EQ030_RS00040	COG2986	histidine ammonia-lyase
EQ030_RS00045	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
EQ030_RS00050	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
EQ030_RS00060	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EQ030_RS00070	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
EQ030_RS00075	COG0359	binds to the 23S rRNA
EQ030_RS00080	COG0305	Participates in initiation and elongation during chromosome replication
EQ030_RS00085	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
EQ030_RS00090	COG1819	glycosyl
EQ030_RS00110	COG0477	Major facilitator Superfamily
EQ030_RS00115	COG0745	RESPONSE REGULATOR receiver
EQ030_RS00120	COG5002	protein histidine kinase activity
EQ030_RS00125	COG4863	YycH protein
EQ030_RS00135	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
EQ030_RS00140	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
EQ030_RS00280	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
EQ030_RS00300	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EQ030_RS00325	COG1215	transferase activity, transferring glycosyl groups
EQ030_RS00355	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EQ030_RS00410	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
EQ030_RS00420	COG0579	oxidoreductase
EQ030_RS00425	COG0028	Belongs to the TPP enzyme family
EQ030_RS00430	COG3527	Alpha-acetolactate decarboxylase
EQ030_RS00435	COG1620	l-lactate permease
EQ030_RS00440	COG0583	DNA-binding transcription factor activity
EQ030_RS00455	COG1136	(ABC) transporter
EQ030_RS00465	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EQ030_RS00510	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EQ030_RS00515	COG1733	regulation of RNA biosynthetic process
EQ030_RS00520	COG2207	Transcriptional regulator
EQ030_RS00525	COG2211	Major facilitator Superfamily
EQ030_RS00530	COG3250	beta-galactosidase activity
EQ030_RS00540	COG0463	Glycosyl transferase, family 2
EQ030_RS00575	COG1028	Short-chain dehydrogenase reductase Sdr
EQ030_RS00590	COG1388	LysM domain
EQ030_RS00595	COG1388	LysM domain
EQ030_RS00600	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
EQ030_RS00635	COG1054	Belongs to the UPF0176 family
EQ030_RS00665	COG1131	(ABC) transporter
EQ030_RS00675	COG5295	Hep Hag repeat protein
EQ030_RS00675	COG4932	domain protein
EQ030_RS00685	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
EQ030_RS00690	COG1511	domain protein
EQ030_RS00690	COG1511	domain protein
EQ030_RS00715	COG1328	CTP reductase activity
EQ030_RS00725	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
EQ030_RS00730	COG0346	lactoylglutathione lyase activity
EQ030_RS00770	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
EQ030_RS00775	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
EQ030_RS00780	COG0579	oxidoreductase
EQ030_RS00820	COG0477	Major facilitator Superfamily
EQ030_RS00830	COG2814	Major facilitator Superfamily
EQ030_RS00835	COG0583	DNA-binding transcription factor activity
EQ030_RS00850	COG0584	glycerophosphoryl diester phosphodiesterase
EQ030_RS00860	COG3961	Belongs to the TPP enzyme family
EQ030_RS00870	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
EQ030_RS00875	COG1691	(AIR) carboxylase
EQ030_RS00880	COG1606	tRNA processing
EQ030_RS00885	COG3875	lactate racemase activity
EQ030_RS00895	COG3835	regulator
EQ030_RS00900	COG0574	Belongs to the PEP-utilizing enzyme family
EQ030_RS00900	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EQ030_RS00905	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
EQ030_RS00915	COG1396	sequence-specific DNA binding
EQ030_RS00920	COG2807	transmembrane transport
EQ030_RS00930	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EQ030_RS00935	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EQ030_RS00940	COG1012	belongs to the aldehyde dehydrogenase family
EQ030_RS00945	COG0531	amino acid
EQ030_RS00960	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
EQ030_RS00970	COG1510	regulation of RNA biosynthetic process
EQ030_RS00975	COG1012	belongs to the aldehyde dehydrogenase family
EQ030_RS00980	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
EQ030_RS00985	COG0583	DNA-binding transcription factor activity
EQ030_RS00990	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EQ030_RS01000	COG4221	oxidoreductase activity
EQ030_RS01015	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
EQ030_RS01015	COG0463	Glycosyl transferase, family 2
EQ030_RS01030	COG0778	Nitroreductase
EQ030_RS01035	COG2843	Capsule synthesis protein
EQ030_RS01040	COG1957	nucleoside hydrolase
EQ030_RS01045	COG0477	Major facilitator Superfamily
EQ030_RS01065	COG1131	(ABC) transporter
EQ030_RS01075	COG0531	amino acid
EQ030_RS01080	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EQ030_RS01085	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
EQ030_RS01090	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
EQ030_RS01095	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
EQ030_RS01110	COG0431	NADPH-dependent FMN reductase
EQ030_RS01115	COG3226	Transcriptional regulator
EQ030_RS01130	COG1620	l-lactate permease
EQ030_RS01135	COG2814	Major facilitator Superfamily
EQ030_RS01165	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EQ030_RS01175	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EQ030_RS01180	COG1447	Phosphotransferase system cellobiose-specific component IIA
EQ030_RS01185	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EQ030_RS01190	COG0765	amino acid transport
EQ030_RS01195	COG1126	abc transporter atp-binding protein
EQ030_RS01210	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EQ030_RS01220	COG1464	Belongs to the NlpA lipoprotein family
EQ030_RS01225	COG0039	L-malate dehydrogenase activity
EQ030_RS01230	COG1940	carbohydrate kinase activity
EQ030_RS01240	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EQ030_RS01245	COG0626	cystathionine gamma-synthase activity
EQ030_RS01270	COG0829	nickel cation binding
EQ030_RS01275	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
EQ030_RS01280	COG0830	nickel cation binding
EQ030_RS01285	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
EQ030_RS01290	COG0804	urea catabolic process
EQ030_RS01295	COG0832	Belongs to the urease beta subunit family
EQ030_RS01300	COG0831	urea catabolic process
EQ030_RS01305	COG4413	Urea transporter
EQ030_RS01310	COG0747	negative chemotaxis
EQ030_RS01335	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EQ030_RS01345	COG0531	amino acid
EQ030_RS01355	COG0561	phosphatase activity
EQ030_RS01365	COG0167	dihydroorotate dehydrogenase activity
EQ030_RS01370	COG3001	Fructosamine kinase
EQ030_RS01400	COG1113	amino acid transport
EQ030_RS01420	COG3189	MarR family transcriptional regulator
EQ030_RS01435	COG0741	lytic transglycosylase activity
EQ030_RS01440	COG0436	Aminotransferase
EQ030_RS01450	COG2608	mercury ion transmembrane transporter activity
EQ030_RS01455	COG2217	Heavy metal translocating P-type atpase
EQ030_RS01460	COG0659	secondary active sulfate transmembrane transporter activity
EQ030_RS01465	COG1136	(ABC) transporter
EQ030_RS01470	COG0577	efflux transmembrane transporter activity
EQ030_RS01475	COG1028	Short-chain dehydrogenase reductase Sdr
EQ030_RS01490	COG0471	metal ion transport
EQ030_RS01495	COG5505	Protein of unknown function (DUF819)
EQ030_RS01510	COG4336	lyase activity
EQ030_RS01520	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
EQ030_RS01525	COG1012	belongs to the aldehyde dehydrogenase family
EQ030_RS01535	COG2409	Drug exporters of the RND superfamily
EQ030_RS01550	COG1473	amidohydrolase
EQ030_RS01575	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EQ030_RS01580	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EQ030_RS01585	COG3425	synthase
EQ030_RS01600	COG3386	PFAM SMP-30 Gluconolaconase
EQ030_RS01605	COG3942	CHAP domain
EQ030_RS01610	COG1757	Na H antiporter
EQ030_RS01615	COG0583	DNA-binding transcription factor activity
EQ030_RS01625	COG1346	cytolysis
EQ030_RS01630	COG0028	Belongs to the TPP enzyme family
EQ030_RS01635	COG1288	antiporter activity
EQ030_RS01640	COG2826	transposase and inactivated derivatives, IS30 family
EQ030_RS01645	COG2190	(PTS) system
EQ030_RS01645	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EQ030_RS01645	COG1263	PTS System
EQ030_RS01655	COG2515	1-aminocyclopropane-1-carboxylate deaminase
EQ030_RS01665	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EQ030_RS01690	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EQ030_RS01700	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
EQ030_RS01710	COG2843	Capsule synthesis protein
EQ030_RS01725	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
EQ030_RS01730	COG1063	alcohol dehydrogenase
EQ030_RS01735	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
EQ030_RS01755	COG1129	ABC transporter
EQ030_RS01775	COG1070	Carbohydrate kinase
EQ030_RS01780	COG1063	alcohol dehydrogenase
EQ030_RS01805	COG3764	Sortase (surface protein transpeptidase)
EQ030_RS01810	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
EQ030_RS01815	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
EQ030_RS01825	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EQ030_RS01830	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EQ030_RS01840	COG2249	NAD(P)H dehydrogenase (quinone) activity
EQ030_RS01845	COG0561	phosphatase activity
EQ030_RS01850	COG0778	Nitroreductase
EQ030_RS01855	COG2723	6-phospho-beta-galactosidase activity
EQ030_RS01860	COG3711	transcriptional antiterminator
EQ030_RS01865	COG3711	transcriptional antiterminator
EQ030_RS01870	COG2514	catechol 2,3-dioxygenase activity
EQ030_RS01880	COG1132	(ABC) transporter
EQ030_RS01885	COG1132	(ABC) transporter
EQ030_RS01900	COG1012	belongs to the aldehyde dehydrogenase family
EQ030_RS01905	COG1846	Transcriptional regulator
EQ030_RS01910	COG0346	lactoylglutathione lyase activity
EQ030_RS01915	COG0346	lactoylglutathione lyase activity
EQ030_RS01920	COG0400	carboxylic ester hydrolase activity
EQ030_RS01930	COG0471	metal ion transport
EQ030_RS01935	COG3949	Membrane
EQ030_RS01945	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
EQ030_RS01950	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EQ030_RS01955	COG0586	Pfam SNARE associated Golgi protein
EQ030_RS01960	COG2271	Major facilitator Superfamily
EQ030_RS01970	COG1289	transmembrane transporter activity
EQ030_RS01985	COG4876	unkown
EQ030_RS01990	COG2357	RelA SpoT domain protein
EQ030_RS02000	COG1802	Transcriptional regulator
EQ030_RS02010	COG2610	gluconate transmembrane transporter activity
EQ030_RS02015	COG1028	Short-chain dehydrogenase reductase Sdr
EQ030_RS02020	COG3949	Membrane
EQ030_RS02040	COG4221	oxidoreductase activity
EQ030_RS02065	COG0107	imidazoleglycerol-phosphate synthase activity
EQ030_RS02070	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
EQ030_RS02075	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
EQ030_RS02080	COG0131	Imidazoleglycerol-phosphate dehydratase
EQ030_RS02085	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
EQ030_RS02090	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
EQ030_RS02095	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
EQ030_RS02100	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
EQ030_RS02105	COG3048	D-serine ammonia-lyase activity
EQ030_RS02110	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
EQ030_RS02120	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
EQ030_RS02125	COG1028	Short-chain dehydrogenase reductase Sdr
EQ030_RS02130	COG1363	Peptidase, m42
EQ030_RS02140	COG0069	glutamate synthase activity
EQ030_RS02150	COG4619	ABC transporter
EQ030_RS02155	COG0390	transport system, permease component
EQ030_RS02160	COG2814	Major facilitator Superfamily
EQ030_RS02165	COG0531	amino acid
EQ030_RS02180	COG3246	L-lysine catabolic process to acetate
EQ030_RS02185	COG1250	3-hydroxyacyl-CoA dehydrogenase
EQ030_RS02200	COG1174	glycine betaine transport
EQ030_RS02210	COG1174	glycine betaine transport
EQ030_RS02220	COG1960	acyl-CoA dehydrogenase activity
EQ030_RS02225	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EQ030_RS02235	COG1116	anion transmembrane transporter activity
EQ030_RS02245	COG1346	cytolysis
EQ030_RS02250	COG1380	Effector of murein hydrolase LrgA
EQ030_RS02255	COG3279	Response regulator of the LytR AlgR family
EQ030_RS02260	COG3275	phosphorelay sensor kinase activity
EQ030_RS02270	COG4187	Peptidase family M20/M25/M40
EQ030_RS02290	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
EQ030_RS02305	COG0025	NhaP-type Na H and K H
EQ030_RS02325	COG2814	Major facilitator Superfamily
EQ030_RS02335	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EQ030_RS02340	COG1388	LysM domain
EQ030_RS02345	COG0588	phosphoglycerate mutase activity
EQ030_RS02355	COG2814	Major facilitator Superfamily
EQ030_RS02380	COG0803	Belongs to the bacterial solute-binding protein 9 family
EQ030_RS02380	COG3443	Belongs to the bacterial solute-binding protein 9 family
EQ030_RS02385	COG2353	YceI-like domain
EQ030_RS02415	COG1959	2 iron, 2 sulfur cluster binding
EQ030_RS02420	COG2116	formate transmembrane transporter activity
EQ030_RS02425	COG0454	-acetyltransferase
EQ030_RS02440	COG0071	Belongs to the small heat shock protein (HSP20) family
EQ030_RS02450	COG1846	Transcriptional regulator
EQ030_RS02470	COG2207	Transcriptional regulator
EQ030_RS02480	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EQ030_RS02480	COG1263	PTS System
EQ030_RS02500	COG1283	sodium-dependent phosphate transmembrane transporter activity
EQ030_RS02505	COG1028	Short-chain dehydrogenase reductase Sdr
EQ030_RS02510	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EQ030_RS02515	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EQ030_RS02520	COG1288	antiporter activity
EQ030_RS02525	COG1349	DNA-binding transcription factor activity
EQ030_RS02530	COG1063	alcohol dehydrogenase
EQ030_RS02535	COG2376	Dihydroxyacetone kinase
EQ030_RS02545	COG0698	ribose 5-phosphate isomerase
EQ030_RS02555	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EQ030_RS02560	COG0492	ferredoxin-NADP+ reductase activity
EQ030_RS02570	COG2814	Major facilitator Superfamily
EQ030_RS02575	COG0604	alcohol dehydrogenase
EQ030_RS02590	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
EQ030_RS02590	COG0463	Glycosyl transferase, family 2
EQ030_RS02595	COG1620	l-lactate permease
EQ030_RS02600	COG0438	transferase activity, transferring glycosyl groups
EQ030_RS02610	COG3850	Histidine kinase
EQ030_RS02610	COG5002	protein histidine kinase activity
EQ030_RS02615	COG0745	RESPONSE REGULATOR receiver
EQ030_RS02620	COG0577	efflux transmembrane transporter activity
EQ030_RS02625	COG1136	(ABC) transporter
EQ030_RS02640	COG4640	response to antibiotic
EQ030_RS02645	COG2814	Major facilitator Superfamily
EQ030_RS02655	COG1566	PFAM secretion protein HlyD family protein
EQ030_RS02660	COG2814	Major facilitator Superfamily
EQ030_RS02685	COG0598	Magnesium transport protein CorA
EQ030_RS02690	COG1304	FMN binding
EQ030_RS02695	COG0786	glutamate:sodium symporter activity
EQ030_RS02710	COG1757	Na H antiporter
EQ030_RS02715	COG2094	Belongs to the DNA glycosylase MPG family
EQ030_RS02720	COG3152	Membrane
EQ030_RS02725	COG1069	ribulokinase activity
EQ030_RS02730	COG4152	abc transporter atp-binding protein
EQ030_RS02735	COG1668	transmembrane transport
EQ030_RS02740	COG2017	converts alpha-aldose to the beta-anomer
EQ030_RS02745	COG2258	MOSC domain
EQ030_RS02750	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
EQ030_RS02755	COG1266	CAAX protease self-immunity
EQ030_RS02760	COG0010	Belongs to the arginase family
EQ030_RS02765	COG0583	DNA-binding transcription factor activity
EQ030_RS02770	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
EQ030_RS02775	COG1228	amidohydrolase
EQ030_RS02780	COG0659	secondary active sulfate transmembrane transporter activity
EQ030_RS02785	COG1473	amidohydrolase
EQ030_RS02790	COG1028	Short-chain dehydrogenase reductase Sdr
EQ030_RS02795	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EQ030_RS02815	COG2801	Transposase and inactivated derivatives
EQ030_RS02825	COG1263	PTS System
EQ030_RS02825	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EQ030_RS02835	COG0385	Bile acid
EQ030_RS02840	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EQ030_RS02865	COG1113	amino acid transport
EQ030_RS02870	COG1785	Belongs to the alkaline phosphatase family
EQ030_RS02875	COG1737	Transcriptional regulator
EQ030_RS02880	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EQ030_RS02880	COG1263	PTS System
EQ030_RS02885	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
EQ030_RS02905	COG0483	inositol monophosphate 1-phosphatase activity
EQ030_RS02910	COG1316	TRANSCRIPTIONal
EQ030_RS02915	COG3383	formate dehydrogenase (NAD+) activity
EQ030_RS02930	COG4193	domain, Protein
EQ030_RS02940	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EQ030_RS02945	COG2076	Multidrug Resistance protein
EQ030_RS02950	COG2076	Multidrug Resistance protein
EQ030_RS02955	COG3942	CHAP domain
EQ030_RS02970	COG1757	Na H antiporter
EQ030_RS02975	COG3942	CHAP domain
EQ030_RS03005	COG0765	amino acid transport
EQ030_RS03010	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EQ030_RS03015	COG1126	abc transporter atp-binding protein
EQ030_RS03020	COG1960	acyl-CoA dehydrogenase activity
EQ030_RS03025	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EQ030_RS03030	COG1268	BioY protein
EQ030_RS03040	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
EQ030_RS03045	COG1609	Transcriptional regulator
EQ030_RS03050	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
EQ030_RS03055	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EQ030_RS03060	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
EQ030_RS03065	COG0725	ABC transporter, periplasmic molybdate-binding protein
EQ030_RS03070	COG4149	molybdate abc transporter
EQ030_RS03085	COG1510	regulation of RNA biosynthetic process
EQ030_RS03090	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EQ030_RS03095	COG0521	Mo-molybdopterin cofactor biosynthetic process
EQ030_RS03100	COG0315	cyclic pyranopterin monophosphate synthase activity
EQ030_RS03110	COG1763	Mo-molybdopterin cofactor biosynthetic process
EQ030_RS03125	COG0746	molybdenum cofactor guanylyltransferase activity
EQ030_RS03130	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
EQ030_RS03140	COG2814	Major facilitator Superfamily
EQ030_RS03160	COG2348	transferase activity, transferring amino-acyl groups
EQ030_RS03165	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EQ030_RS03185	COG4975	Glucose uptake
EQ030_RS03195	COG0551	DNA topoisomerase type I activity
EQ030_RS03195	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EQ030_RS03200	COG2252	PERMEase
EQ030_RS03210	COG0051	transcription antitermination factor activity, RNA binding
EQ030_RS03215	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
EQ030_RS03220	COG0088	Forms part of the polypeptide exit tunnel
EQ030_RS03225	COG0089	rRNA binding
EQ030_RS03230	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
EQ030_RS03235	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
EQ030_RS03240	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
EQ030_RS03245	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
EQ030_RS03250	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
EQ030_RS03255	COG0255	Belongs to the universal ribosomal protein uL29 family
EQ030_RS03260	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
EQ030_RS03265	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
EQ030_RS03270	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
EQ030_RS03275	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
EQ030_RS03280	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
EQ030_RS03285	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
EQ030_RS03290	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
EQ030_RS03295	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
EQ030_RS03300	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
EQ030_RS03305	COG1841	ribosomal large subunit assembly
EQ030_RS03310	COG0200	Binds to the 23S rRNA
EQ030_RS03315	COG0201	protein transport
EQ030_RS03320	COG0563	adenylate kinase activity
EQ030_RS03330	COG0257	Belongs to the bacterial ribosomal protein bL36 family
EQ030_RS03335	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
EQ030_RS03340	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
EQ030_RS03345	COG0202	RNA polymerase activity
EQ030_RS03350	COG0203	ribosomal protein L17
EQ030_RS03355	COG1122	ATPase activity
EQ030_RS03360	COG1122	ATPase activity
EQ030_RS03370	COG0101	tRNA pseudouridine synthase activity
EQ030_RS03375	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
EQ030_RS03380	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
EQ030_RS03390	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EQ030_RS03395	COG2130	NADP-dependent
EQ030_RS03400	COG0604	alcohol dehydrogenase
EQ030_RS03405	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EQ030_RS03420	COG1302	Protein conserved in bacteria
EQ030_RS03425	COG4264	IucA IucC family
EQ030_RS03430	COG2814	Major facilitator Superfamily
EQ030_RS03435	COG4264	IucA IucC family
EQ030_RS03440	COG3457	Alanine racemase
EQ030_RS03445	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
EQ030_RS03450	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EQ030_RS03455	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EQ030_RS03460	COG3314	Sporulation integral membrane protein YlbJ
EQ030_RS03465	COG2329	Antibiotic biosynthesis monooxygenase
EQ030_RS03475	COG1988	membrane-bound metal-dependent
EQ030_RS03480	COG4284	Utp--glucose-1-phosphate uridylyltransferase
EQ030_RS03485	COG1272	protein, Hemolysin III
EQ030_RS03500	COG0489	protein tyrosine kinase activity
EQ030_RS03555	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
EQ030_RS03565	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EQ030_RS03570	COG0246	Mannitol dehydrogenase
EQ030_RS03580	COG3711	transcriptional antiterminator
EQ030_RS03585	COG2213	PTS system mannitol-specific
EQ030_RS03600	COG1119	ATPase activity
EQ030_RS03625	COG0640	Transcriptional regulator
EQ030_RS03630	COG0702	epimerase
EQ030_RS03635	COG2186	Transcriptional regulator
EQ030_RS03640	COG1482	cell wall glycoprotein biosynthetic process
EQ030_RS03650	COG2855	membrane
EQ030_RS03665	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EQ030_RS03670	COG0783	Belongs to the Dps family
EQ030_RS03675	COG0813	purine-nucleoside phosphorylase activity
EQ030_RS03680	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
EQ030_RS03685	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
EQ030_RS03690	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
EQ030_RS03700	COG1854	S-ribosylhomocysteine lyase activity
EQ030_RS03720	COG5146	pantothenate kinase activity
EQ030_RS03725	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EQ030_RS03730	COG3343	RNA polymerase activity
EQ030_RS03735	COG0504	CTP synthase activity
EQ030_RS03740	COG0191	fructose-bisphosphate aldolase activity
EQ030_RS03745	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EQ030_RS03755	COG1012	belongs to the aldehyde dehydrogenase family
EQ030_RS03760	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
EQ030_RS03765	COG0254	rRNA binding
EQ030_RS03770	COG1435	thymidine kinase activity
EQ030_RS03775	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
EQ030_RS03780	COG2890	protein-(glutamine-N5) methyltransferase activity
EQ030_RS03785	COG0009	L-threonylcarbamoyladenylate synthase
EQ030_RS03790	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EQ030_RS03795	COG4475	Protein of unknown function (DUF436)
EQ030_RS03800	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
EQ030_RS03805	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
EQ030_RS03810	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
EQ030_RS03820	COG0356	it plays a direct role in the translocation of protons across the membrane
EQ030_RS03825	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EQ030_RS03830	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
EQ030_RS03835	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EQ030_RS03840	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
EQ030_RS03845	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
EQ030_RS03850	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
EQ030_RS03855	COG0355	proton-transporting ATP synthase activity, rotational mechanism
EQ030_RS03865	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EQ030_RS03870	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EQ030_RS03880	COG0629	single-stranded DNA binding
EQ030_RS03885	COG1388	LysM domain
EQ030_RS03890	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
EQ030_RS03900	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
EQ030_RS03905	COG0352	thiamine-phosphate diphosphorylase activity
EQ030_RS03910	COG0706	membrane insertase activity
EQ030_RS03915	COG1418	mRNA catabolic process
EQ030_RS03925	COG1937	Protein conserved in bacteria
EQ030_RS03940	COG0772	Belongs to the SEDS family
EQ030_RS03945	COG1181	Belongs to the D-alanine--D-alanine ligase family
EQ030_RS03950	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
EQ030_RS03955	COG0513	Belongs to the DEAD box helicase family
EQ030_RS03965	COG3428	Bacterial PH domain
EQ030_RS03970	COG3402	PFAM membrane-flanked domain
EQ030_RS03975	COG0736	holo-[acyl-carrier-protein] synthase activity
EQ030_RS03980	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EQ030_RS03990	COG2337	Toxic component of a toxin-antitoxin (TA) module
EQ030_RS03995	COG2208	phosphoserine phosphatase activity
EQ030_RS04015	COG2183	response to ionizing radiation
EQ030_RS04020	COG3091	SprT-like family
EQ030_RS04050	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EQ030_RS04055	COG0066	3-isopropylmalate dehydratase activity
EQ030_RS04060	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
EQ030_RS04065	COG0473	3-isopropylmalate dehydrogenase activity
EQ030_RS04070	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EQ030_RS04075	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
EQ030_RS04080	COG0440	acetolactate synthase activity
EQ030_RS04085	COG0028	Belongs to the TPP enzyme family
EQ030_RS04090	COG0129	dihydroxy-acid dehydratase activity
EQ030_RS04095	COG0802	atpase or kinase
EQ030_RS04100	COG1214	PFAM Peptidase M22, glycoprotease
EQ030_RS04105	COG0456	acetyltransferase
EQ030_RS04110	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
EQ030_RS04120	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
EQ030_RS04125	COG0488	(ABC) transporter
EQ030_RS04130	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
EQ030_RS04135	COG2391	methyltransferase activity
EQ030_RS04140	COG0425	Belongs to the sulfur carrier protein TusA family
EQ030_RS04145	COG1609	Transcriptional regulator
EQ030_RS04150	COG1621	beta-fructofuranosidase activity
EQ030_RS04155	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EQ030_RS04160	COG3279	Response regulator of the LytR AlgR family
EQ030_RS04165	COG3290	protein histidine kinase activity
EQ030_RS04175	COG4512	PFAM Accessory gene regulator B
EQ030_RS04180	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EQ030_RS04200	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
EQ030_RS04205	COG0459	protein refolding
EQ030_RS04240	COG1725	Transcriptional regulator
EQ030_RS04255	COG1131	(ABC) transporter
EQ030_RS04300	COG2706	6-phosphogluconolactonase activity
EQ030_RS04310	COG1012	belongs to the aldehyde dehydrogenase family
EQ030_RS04315	COG1227	inorganic diphosphatase activity
EQ030_RS04320	COG1335	isochorismatase
EQ030_RS04330	COG0471	metal ion transport
EQ030_RS04335	COG0077	Prephenate dehydratase
EQ030_RS04345	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
EQ030_RS04350	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
EQ030_RS04355	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
EQ030_RS04365	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
EQ030_RS04370	COG4496	protein, YerC YecD
EQ030_RS04380	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
EQ030_RS04390	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
EQ030_RS04395	COG4851	CamS sex pheromone cAM373 precursor
EQ030_RS04400	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EQ030_RS04405	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EQ030_RS04410	COG0154	amidase activity
EQ030_RS04415	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EQ030_RS04420	COG1597	lipid kinase activity
EQ030_RS04425	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EQ030_RS04435	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EQ030_RS04445	COG1528	Iron-storage protein
EQ030_RS04465	COG2801	Transposase and inactivated derivatives
EQ030_RS04470	COG4129	membrane
EQ030_RS04475	COG0024	Methionine aminopeptidase
EQ030_RS04490	COG4585	Histidine kinase
EQ030_RS04495	COG2197	response regulator
EQ030_RS04500	COG1295	ribonuclease BN
EQ030_RS04510	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EQ030_RS04515	COG4840	Belongs to the UPF0435 family
EQ030_RS04520	COG2309	aminopeptidase activity
EQ030_RS04525	COG1607	acyl-coa hydrolase
EQ030_RS04530	COG0535	radical SAM domain protein
EQ030_RS04540	COG0693	protein deglycase activity
EQ030_RS04545	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EQ030_RS04550	COG2137	regulation of response to DNA damage stimulus
EQ030_RS04560	COG1134	teichoic acid transport
EQ030_RS04570	COG1988	membrane-bound metal-dependent
EQ030_RS04580	COG3557	Belongs to the UPF0374 family
EQ030_RS04590	COG4129	membrane
EQ030_RS04595	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
EQ030_RS04600	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EQ030_RS04605	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EQ030_RS04610	COG0735	belongs to the Fur family
EQ030_RS04775	COG1126	abc transporter atp-binding protein
EQ030_RS04780	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
EQ030_RS04790	COG0363	glucosamine-6-phosphate deaminase activity
EQ030_RS04805	COG0114	fumarate hydratase activity
EQ030_RS04810	COG0564	pseudouridine synthase activity
EQ030_RS04815	COG2203	Gaf domain
EQ030_RS04815	COG4585	Histidine kinase
EQ030_RS04820	COG2197	response regulator
EQ030_RS04835	COG1682	transport, permease protein
EQ030_RS04840	COG0788	formyltetrahydrofolate deformylase activity
EQ030_RS04850	COG4399	Belongs to the UPF0754 family
EQ030_RS04855	COG3679	Belongs to the UPF0342 family
EQ030_RS04860	COG0420	3'-5' exonuclease activity
EQ030_RS04865	COG4717	serine-type aminopeptidase activity
EQ030_RS04870	COG3481	metal-dependent phosphohydrolase, HD sub domain
EQ030_RS04875	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EQ030_RS04890	COG0537	adenosine 5'-monophosphoramidase activity
EQ030_RS04895	COG1131	(ABC) transporter
EQ030_RS04900	COG4473	ABC transporter
EQ030_RS04910	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
EQ030_RS04915	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
EQ030_RS04920	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
EQ030_RS04925	COG3545	Serine hydrolase
EQ030_RS04975	COG0318	PFAM AMP-dependent synthetase and ligase
EQ030_RS04985	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
EQ030_RS04995	COG1506	peptidase
EQ030_RS05000	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
EQ030_RS05005	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
EQ030_RS05015	COG0656	L-ascorbic acid biosynthetic process
EQ030_RS05020	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EQ030_RS05025	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EQ030_RS05035	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
EQ030_RS05065	COG4193	domain, Protein
EQ030_RS05065	COG5632	N-Acetylmuramoyl-L-alanine amidase
EQ030_RS05065	COG3266	domain, Protein
EQ030_RS05085	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EQ030_RS05085	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EQ030_RS05090	COG0307	riboflavin synthase, alpha
EQ030_RS05095	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EQ030_RS05095	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EQ030_RS05100	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
EQ030_RS05110	COG2267	carboxylic ester hydrolase activity
EQ030_RS05115	COG0039	L-malate dehydrogenase activity
EQ030_RS05125	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
EQ030_RS05130	COG1242	4 iron, 4 sulfur cluster binding
EQ030_RS05135	COG2814	Major facilitator Superfamily
EQ030_RS05140	COG0495	leucyl-tRNA aminoacylation
EQ030_RS05155	COG2244	polysaccharide biosynthetic process
EQ030_RS05160	COG1187	pseudouridine synthase activity
EQ030_RS05170	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EQ030_RS05175	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EQ030_RS05180	COG0510	thiamine kinase activity
EQ030_RS05185	COG0220	tRNA (guanine-N7-)-methyltransferase activity
EQ030_RS05190	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EQ030_RS05195	COG5584	Small secreted protein
EQ030_RS05200	COG1363	Peptidase, m42
EQ030_RS05205	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EQ030_RS05210	COG4848	Belongs to the UPF0354 family
EQ030_RS05215	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EQ030_RS05220	COG1674	ftsk spoiiie
EQ030_RS05225	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
EQ030_RS05230	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
EQ030_RS05240	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
EQ030_RS05240	COG1605	Chorismate mutase
EQ030_RS05245	COG1609	Transcriptional regulator
EQ030_RS05250	COG0123	including yeast histone deacetylase and acetoin utilization protein
EQ030_RS05255	COG0454	-acetyltransferase
EQ030_RS05260	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EQ030_RS05265	COG2759	Belongs to the formate--tetrahydrofolate ligase family
EQ030_RS05270	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EQ030_RS05275	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
EQ030_RS05280	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EQ030_RS05285	COG0204	Acyl-transferase
EQ030_RS05290	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EQ030_RS05290	COG1263	PTS System
EQ030_RS05300	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EQ030_RS05310	COG1764	response to oxidative stress
EQ030_RS05315	COG0584	glycerophosphoryl diester phosphodiesterase
EQ030_RS05325	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
EQ030_RS05335	COG1956	GAF domain-containing protein
EQ030_RS05340	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
EQ030_RS05345	COG1104	cysteine desulfurase activity
EQ030_RS05350	COG0301	tRNA thio-modification
EQ030_RS05360	COG0616	signal peptide processing
EQ030_RS05365	COG1714	RDD family
EQ030_RS05370	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
EQ030_RS05375	COG0827	DNA restriction-modification system
EQ030_RS05380	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
EQ030_RS05390	COG0589	response to stress
EQ030_RS05395	COG0686	Belongs to the AlaDH PNT family
EQ030_RS05400	COG3142	Participates in the control of copper homeostasis
EQ030_RS05405	COG0006	proline dipeptidase activity
EQ030_RS05410	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
EQ030_RS05420	COG4109	DRTGG domain
EQ030_RS05425	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
EQ030_RS05430	COG0587	DNA-directed DNA polymerase activity
EQ030_RS05435	COG0281	malic enzyme
EQ030_RS05440	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
EQ030_RS05445	COG0825	malonyl-CoA metabolic process
EQ030_RS05450	COG0205	6-phosphofructokinase activity
EQ030_RS05455	COG0469	pyruvate kinase activity
EQ030_RS05460	COG1113	amino acid transport
EQ030_RS05465	COG0372	Belongs to the citrate synthase family
EQ030_RS05470	COG0538	isocitrate dehydrogenase activity
EQ030_RS05475	COG0745	RESPONSE REGULATOR receiver
EQ030_RS05480	COG5002	protein histidine kinase activity
EQ030_RS05485	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EQ030_RS05485	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EQ030_RS05490	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
EQ030_RS05495	COG0237	dephospho-CoA kinase activity
EQ030_RS05500	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EQ030_RS05505	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
EQ030_RS05515	COG1484	DNA-dependent DNA replication
EQ030_RS05520	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EQ030_RS05525	COG0833	amino acid
EQ030_RS05530	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
EQ030_RS05535	COG0291	Belongs to the bacterial ribosomal protein bL35 family
EQ030_RS05540	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
EQ030_RS05545	COG4112	unkown
EQ030_RS05555	COG0544	peptidyl-prolyl cis-trans isomerase activity
EQ030_RS05560	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
EQ030_RS05565	COG0218	Necessary for normal cell division and for the maintenance of normal septation
EQ030_RS05570	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
EQ030_RS05575	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EQ030_RS05580	COG0181	hydroxymethylbilane synthase activity
EQ030_RS05590	COG0113	porphobilinogen synthase activity
EQ030_RS05595	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
EQ030_RS05610	COG2818	Glycosylase
EQ030_RS05615	COG0525	valine-tRNA ligase activity
EQ030_RS05620	COG0285	dihydrofolate synthase activity
EQ030_RS05630	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
EQ030_RS05635	COG2003	Belongs to the UPF0758 family
EQ030_RS05665	COG0261	This protein binds to 23S rRNA in the presence of protein L20
EQ030_RS05670	COG2868	ribosomal protein
EQ030_RS05675	COG0211	Belongs to the bacterial ribosomal protein bL27 family
EQ030_RS05680	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
EQ030_RS05685	COG4492	Belongs to the UPF0735 family
EQ030_RS05690	COG0632	four-way junction helicase activity
EQ030_RS05695	COG2255	four-way junction helicase activity
EQ030_RS05700	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
EQ030_RS05705	COG0343	queuine tRNA-ribosyltransferase activity
EQ030_RS05710	COG1862	Preprotein translocase
EQ030_RS05715	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EQ030_RS05715	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EQ030_RS05720	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
EQ030_RS05720	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
EQ030_RS05725	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EQ030_RS05735	COG1490	D-aminoacyl-tRNA deacylase activity
EQ030_RS05740	COG0860	N-Acetylmuramoyl-L-alanine amidase
EQ030_RS05745	COG0124	histidyl-tRNA synthetase
EQ030_RS05750	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
EQ030_RS05760	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
EQ030_RS05765	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
EQ030_RS05770	COG1959	2 iron, 2 sulfur cluster binding
EQ030_RS05775	COG3237	CsbD-like
EQ030_RS05780	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EQ030_RS05785	COG1132	(ABC) transporter
EQ030_RS05795	COG0488	(ABC) transporter
EQ030_RS05800	COG1104	cysteine desulfurase activity
EQ030_RS05805	COG0482	sulfurtransferase activity
EQ030_RS05815	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
EQ030_RS05820	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EQ030_RS05825	COG4472	Bacterial protein of unknown function (DUF965)
EQ030_RS05830	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
EQ030_RS05835	COG3906	Belongs to the UPF0473 family
EQ030_RS05840	COG4122	O-methyltransferase activity
EQ030_RS05845	COG0826	peptidase U32
EQ030_RS05850	COG0826	peptidase U32
EQ030_RS05855	COG0572	uridine kinase
EQ030_RS05860	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EQ030_RS05865	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
EQ030_RS05870	COG1984	allophanate hydrolase subunit 2
EQ030_RS05880	COG0439	Biotin carboxylase
EQ030_RS05885	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
EQ030_RS05890	COG1914	H( )-stimulated, divalent metal cation uptake system
EQ030_RS05895	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EQ030_RS05900	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
EQ030_RS05905	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
EQ030_RS05910	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
EQ030_RS05915	COG1534	Rna-binding protein
EQ030_RS05920	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
EQ030_RS05925	COG1713	HD superfamily hydrolase involved in NAD metabolism
EQ030_RS05930	COG0799	negative regulation of ribosome biogenesis
EQ030_RS05935	COG2226	methyltransferase
EQ030_RS05940	COG1596	polysaccharide export
EQ030_RS05940	COG1555	photosystem II stabilization
EQ030_RS05945	COG2131	deaminase
EQ030_RS05950	COG2333	competence protein COMEC
EQ030_RS05950	COG0658	competence protein
EQ030_RS05955	COG1466	dna polymerase III delta subunit
EQ030_RS05960	COG0268	Binds directly to 16S ribosomal RNA
EQ030_RS05965	COG0481	GTPase activity
EQ030_RS05970	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EQ030_RS05975	COG1420	regulation of RNA biosynthetic process
EQ030_RS05980	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
EQ030_RS05985	COG0443	Heat shock 70 kDa protein
EQ030_RS05990	COG0484	heat shock protein binding
EQ030_RS05995	COG2264	protein methyltransferase activity
EQ030_RS06000	COG1385	rRNA (uridine-N3-)-methyltransferase activity
EQ030_RS06005	COG0828	Belongs to the bacterial ribosomal protein bS21 family
EQ030_RS06010	COG1030	water channel activity
EQ030_RS06015	COG4864	UPF0365 protein
EQ030_RS06025	COG1702	phosphate starvation-inducible protein PhoH
EQ030_RS06030	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
EQ030_RS06040	COG0295	cytidine deaminase activity
EQ030_RS06045	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
EQ030_RS06050	COG1381	Involved in DNA repair and RecF pathway recombination
EQ030_RS06055	COG0423	glycine-tRNA ligase activity
EQ030_RS06060	COG0517	IMP dehydrogenase activity
EQ030_RS06065	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
EQ030_RS06075	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EQ030_RS06080	COG2384	SAM-dependent methyltransferase
EQ030_RS06085	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
EQ030_RS06090	COG0513	Belongs to the DEAD box helicase family
EQ030_RS06095	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
EQ030_RS06100	COG1121	(ABC) transporter
EQ030_RS06105	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EQ030_RS06115	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EQ030_RS06120	COG0768	penicillin binding
EQ030_RS06125	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EQ030_RS06130	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
EQ030_RS06135	COG0705	Rhomboid family
EQ030_RS06135	COG0457	Tetratricopeptide repeat
EQ030_RS06140	COG4483	Protein conserved in bacteria
EQ030_RS06145	COG1940	carbohydrate kinase activity
EQ030_RS06150	COG0011	TIGRFAM Protein of
EQ030_RS06155	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EQ030_RS06160	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EQ030_RS06165	COG1459	type II secretion system
EQ030_RS06170	COG4537	Required for transformation and DNA binding
EQ030_RS06190	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
EQ030_RS06195	COG0404	The glycine cleavage system catalyzes the degradation of glycine
EQ030_RS06200	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EQ030_RS06205	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EQ030_RS06210	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EQ030_RS06215	COG0095	Lipoate-protein ligase
EQ030_RS06230	COG0006	proline dipeptidase activity
EQ030_RS06235	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
EQ030_RS06240	COG0511	ligase activity, forming carbon-carbon bonds
EQ030_RS06245	COG0439	Biotin carboxylase
EQ030_RS06250	COG1302	Protein conserved in bacteria
EQ030_RS06255	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EQ030_RS06260	COG1570	exodeoxyribonuclease VII activity
EQ030_RS06265	COG1722	exodeoxyribonuclease VII activity
EQ030_RS06280	COG1438	arginine binding
EQ030_RS06285	COG0497	DNA recombination
EQ030_RS06295	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EQ030_RS06300	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EQ030_RS06305	COG0022	dehydrogenase e1 component
EQ030_RS06310	COG0508	dehydrogenase complex catalyzes the overall conversion of
EQ030_RS06320	COG4129	membrane
EQ030_RS06325	COG2195	Cleaves the N-terminal amino acid of tripeptides
EQ030_RS06335	COG1609	Transcriptional regulator
EQ030_RS06340	COG0366	Alpha amylase catalytic
EQ030_RS06350	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
EQ030_RS06355	COG1234	tRNA 3'-trailer cleavage
EQ030_RS06360	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EQ030_RS06370	COG0667	Aldo Keto reductase
EQ030_RS06375	COG0494	nUDIX hydrolase
EQ030_RS06380	COG0735	belongs to the Fur family
EQ030_RS06385	COG4974	Belongs to the 'phage' integrase family
EQ030_RS06395	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
EQ030_RS06400	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
EQ030_RS06405	COG1187	pseudouridine synthase activity
EQ030_RS06410	COG0745	RESPONSE REGULATOR receiver
EQ030_RS06425	COG1141	Ferredoxin
EQ030_RS06435	COG0514	ATP-dependent DNA helicase (RecQ)
EQ030_RS06440	COG1388	LysM domain
EQ030_RS06445	COG0492	ferredoxin-NADP+ reductase activity
EQ030_RS06450	COG0252	asparaginase activity
EQ030_RS06455	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
EQ030_RS06460	COG0539	negative regulation of cytoplasmic translation
EQ030_RS06465	COG1160	GTP binding
EQ030_RS06470	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
EQ030_RS06485	COG2226	methyltransferase
EQ030_RS06490	COG0142	geranyltranstransferase activity
EQ030_RS06495	COG0105	UTP biosynthetic process
EQ030_RS06500	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
EQ030_RS06505	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
EQ030_RS06510	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
EQ030_RS06525	COG4347	Protein of unknown function (DUF1405)
EQ030_RS06530	COG2738	Putative neutral zinc metallopeptidase
EQ030_RS06535	COG1694	Mazg nucleotide pyrophosphohydrolase
EQ030_RS06540	COG0438	transferase activity, transferring glycosyl groups
EQ030_RS06545	COG0617	tRNA 3'-terminal CCA addition
EQ030_RS06550	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
EQ030_RS06550	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
EQ030_RS06555	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EQ030_RS06555	COG1199	ATP-dependent helicase activity
EQ030_RS06560	COG0017	Asparaginyl-tRNA synthetase
EQ030_RS06565	COG3935	DnaD domain protein
EQ030_RS06570	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
EQ030_RS06580	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EQ030_RS06580	COG4499	WXG100 protein secretion system (Wss), protein YukC
EQ030_RS06585	COG3331	DNA recombination
EQ030_RS06595	COG4474	Belongs to the UPF0398 family
EQ030_RS06600	COG3599	regulation of cell shape
EQ030_RS06610	COG0116	Belongs to the methyltransferase superfamily
EQ030_RS06615	COG2962	Rard protein
EQ030_RS06630	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
EQ030_RS06635	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EQ030_RS06640	COG0328	RNA-DNA hybrid ribonuclease activity
EQ030_RS06645	COG3545	Serine hydrolase
EQ030_RS06650	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
EQ030_RS06660	COG1413	lyase activity
EQ030_RS06665	COG1413	lyase activity
EQ030_RS06675	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
EQ030_RS06695	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EQ030_RS06705	COG4479	Belongs to the UPF0346 family
EQ030_RS06710	COG0793	Belongs to the peptidase S41A family
EQ030_RS06720	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
EQ030_RS06725	COG0671	phosphoesterase, PA-phosphatase related
EQ030_RS06730	COG0745	RESPONSE REGULATOR receiver
EQ030_RS06735	COG5002	protein histidine kinase activity
EQ030_RS06740	COG0567	Dehydrogenase, E1 component
EQ030_RS06745	COG0508	dehydrogenase complex catalyzes the overall conversion of
EQ030_RS06785	COG0673	inositol 2-dehydrogenase activity
EQ030_RS06790	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
EQ030_RS06795	COG1121	(ABC) transporter
EQ030_RS06820	COG0714	Associated with various cellular activities
EQ030_RS06825	COG4548	von Willebrand factor, type A
EQ030_RS06830	COG1114	Component of the transport system for branched-chain amino acids
EQ030_RS06835	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EQ030_RS06840	COG3853	Toxic anion resistance protein (TelA)
EQ030_RS06850	COG1254	Belongs to the acylphosphatase family
EQ030_RS06860	COG1278	Cold shock
EQ030_RS06875	COG1473	amidohydrolase
EQ030_RS06880	COG2171	N-acyltransferase activity
EQ030_RS06885	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
EQ030_RS06890	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EQ030_RS06895	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EQ030_RS06900	COG0527	aspartate kinase activity
EQ030_RS06910	COG0488	(ABC) transporter
EQ030_RS06915	COG2996	Protein conserved in bacteria
EQ030_RS06920	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
EQ030_RS06925	COG0573	inorganic phosphate transmembrane transporter activity
EQ030_RS06930	COG0581	inorganic phosphate transmembrane transporter activity
EQ030_RS06935	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
EQ030_RS06940	COG0704	Plays a role in the regulation of phosphate uptake
EQ030_RS06945	COG1164	Oligoendopeptidase f
EQ030_RS06955	COG4607	ABC-type enterochelin transport system periplasmic component
EQ030_RS06965	COG2348	transferase activity, transferring amino-acyl groups
EQ030_RS06970	COG2348	transferase activity, transferring amino-acyl groups
EQ030_RS06980	COG0159	tryptophan synthase activity
EQ030_RS06985	COG0133	tryptophan synthase activity
EQ030_RS06990	COG0135	phosphoribosylanthranilate isomerase activity
EQ030_RS06995	COG0134	indole-3-glycerol-phosphate synthase activity
EQ030_RS07000	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EQ030_RS07005	COG0512	Glutamine amidotransferase of anthranilate synthase
EQ030_RS07010	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EQ030_RS07020	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EQ030_RS07030	COG1363	Peptidase, m42
EQ030_RS07045	COG0287	Prephenate dehydrogenase
EQ030_RS07050	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EQ030_RS07055	COG1942	4-Oxalocrotonate Tautomerase
EQ030_RS07070	COG1879	ABC-type sugar transport system periplasmic component
EQ030_RS07075	COG1172	Belongs to the binding-protein-dependent transport system permease family
EQ030_RS07080	COG1129	ABC transporter
EQ030_RS07085	COG1869	D-ribose catabolic process
EQ030_RS07090	COG1609	Transcriptional regulator
EQ030_RS07095	COG0392	lysyltransferase activity
EQ030_RS07095	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
EQ030_RS07100	COG0628	permease
EQ030_RS07120	COG3711	transcriptional antiterminator
EQ030_RS07125	COG1115	amino acid carrier protein
EQ030_RS07130	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EQ030_RS07140	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
EQ030_RS07145	COG4841	protein insertion into membrane
EQ030_RS07150	COG0824	Thioesterase
EQ030_RS07155	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
EQ030_RS07160	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EQ030_RS07165	COG1970	mechanosensitive ion channel activity
EQ030_RS07170	COG0419	ATPase involved in DNA repair
EQ030_RS07175	COG0420	3'-5' exonuclease activity
EQ030_RS07180	COG4846	Membrane protein involved in cytochrome C biogenesis
EQ030_RS07190	COG3763	UPF0154 protein
EQ030_RS07210	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
EQ030_RS07220	COG0516	GMP reductase activity
EQ030_RS07225	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
EQ030_RS07230	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EQ030_RS07235	COG2826	transposase and inactivated derivatives, IS30 family
EQ030_RS07245	COG3639	organic phosphonate transmembrane transporter activity
EQ030_RS07250	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
EQ030_RS07265	COG0737	Belongs to the 5'-nucleotidase family
EQ030_RS07280	COG0753	catalase activity
EQ030_RS07285	COG0833	amino acid
EQ030_RS07295	COG0561	phosphatase activity
EQ030_RS07300	COG0083	homoserine kinase activity
EQ030_RS07305	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
EQ030_RS07310	COG0460	homoserine dehydrogenase
EQ030_RS07315	COG0527	aspartate kinase activity
EQ030_RS07345	COG2197	response regulator
EQ030_RS07350	COG4585	Histidine kinase
EQ030_RS07350	COG2203	Gaf domain
EQ030_RS07355	COG0842	Transport permease protein
EQ030_RS07360	COG1131	(ABC) transporter
EQ030_RS07370	COG0174	glutamine synthetase
EQ030_RS07375	COG0789	Transcriptional regulator
EQ030_RS07380	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
EQ030_RS07385	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EQ030_RS07390	COG0386	Belongs to the glutathione peroxidase family
EQ030_RS07395	COG1923	regulation of RNA biosynthetic process
EQ030_RS07400	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
EQ030_RS07410	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
EQ030_RS07415	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
EQ030_RS07420	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
EQ030_RS07435	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
EQ030_RS07440	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
EQ030_RS07450	COG4550	Control of competence regulator ComK, YlbF/YmcA
EQ030_RS07455	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EQ030_RS07480	COG1013	pyruvate-flavodoxin oxidoreductase activity
EQ030_RS07485	COG0674	pyruvate-flavodoxin oxidoreductase activity
EQ030_RS07485	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
EQ030_RS07490	COG1692	metallophosphoesterase
EQ030_RS07500	COG1418	mRNA catabolic process
EQ030_RS07505	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
EQ030_RS07510	COG1058	Belongs to the CinA family
EQ030_RS07510	COG1546	Belongs to the CinA family
EQ030_RS07530	COG0300	oxidoreductase activity
EQ030_RS07535	COG0612	Peptidase, M16
EQ030_RS07540	COG0612	Peptidase, M16
EQ030_RS07545	COG2188	Transcriptional regulator
EQ030_RS07550	COG1674	ftsk spoiiie
EQ030_RS07555	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EQ030_RS07560	COG1185	polyribonucleotide nucleotidyltransferase activity
EQ030_RS07565	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
EQ030_RS07570	COG0196	riboflavin kinase activity
EQ030_RS07575	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
EQ030_RS07580	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
EQ030_RS07595	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
EQ030_RS07600	COG1358	cellular component organization or biogenesis
EQ030_RS07605	COG2740	Nucleic-acid-binding protein implicated in transcription termination
EQ030_RS07610	COG0195	Participates in both transcription termination and antitermination
EQ030_RS07615	COG0779	Required for maturation of 30S ribosomal subunits
EQ030_RS07620	COG2176	DNA-directed DNA polymerase activity
EQ030_RS07625	COG0442	prolyl-tRNA aminoacylation
EQ030_RS07635	COG4589	Belongs to the CDS family
EQ030_RS07640	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
EQ030_RS07645	COG0233	cytoplasmic translational termination
EQ030_RS07650	COG0528	UMP kinase activity
EQ030_RS07655	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
EQ030_RS07660	COG0052	Belongs to the universal ribosomal protein uS2 family
EQ030_RS07665	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
EQ030_RS07670	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
EQ030_RS07675	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
EQ030_RS07680	COG4974	Belongs to the 'phage' integrase family
EQ030_RS07685	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
EQ030_RS07690	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EQ030_RS07695	COG0758	DNA mediated transformation
EQ030_RS07705	COG0045	succinate-CoA ligase (ADP-forming) activity
EQ030_RS07710	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EQ030_RS07720	COG4485	Bacterial membrane protein, YfhO
EQ030_RS07730	COG0335	large ribosomal subunit rRNA binding
EQ030_RS07735	COG0336	Belongs to the RNA methyltransferase TrmD family
EQ030_RS07740	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
EQ030_RS07745	COG0228	four-way junction DNA binding
EQ030_RS07750	COG1028	Short-chain dehydrogenase reductase Sdr
EQ030_RS07755	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EQ030_RS07760	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EQ030_RS07765	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
EQ030_RS07770	COG0552	protein localization to endoplasmic reticulum
EQ030_RS07775	COG1196	nuclear chromosome segregation
EQ030_RS07780	COG0571	ribonuclease III activity
EQ030_RS07785	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EQ030_RS07800	COG0416	fatty acid biosynthetic process
EQ030_RS07805	COG1349	DNA-binding transcription factor activity
EQ030_RS07815	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
EQ030_RS07820	COG1760	l-serine dehydratase
EQ030_RS07825	COG1760	l-serine dehydratase
EQ030_RS07830	COG1461	Dihydroxyacetone kinase
EQ030_RS07835	COG1302	Protein conserved in bacteria
EQ030_RS07840	COG0227	Belongs to the bacterial ribosomal protein bL28 family
EQ030_RS07845	COG1564	THIamine pyrophosphokinase
EQ030_RS07850	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
EQ030_RS07855	COG1162	GTPase activity
EQ030_RS07865	COG0631	protein serine/threonine phosphatase activity
EQ030_RS07870	COG0820	rRNA (adenine-C2-)-methyltransferase activity
EQ030_RS07875	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EQ030_RS07875	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EQ030_RS07880	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EQ030_RS07885	COG0242	peptide deformylase activity
EQ030_RS07900	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EQ030_RS07905	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EQ030_RS07910	COG1758	RNA polymerase activity
EQ030_RS07915	COG0194	GDP metabolic process
EQ030_RS07920	COG1293	RNA-binding protein homologous to eukaryotic snRNP
EQ030_RS07930	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EQ030_RS07940	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
EQ030_RS07945	COG0284	orotidine-5'-phosphate decarboxylase activity
EQ030_RS07950	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
EQ030_RS07955	COG0505	Belongs to the CarA family
EQ030_RS07965	COG0540	Belongs to the ATCase OTCase family
EQ030_RS07975	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
EQ030_RS07980	COG0564	pseudouridine synthase activity
EQ030_RS07985	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
EQ030_RS07995	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
EQ030_RS08000	COG3599	regulation of cell shape
EQ030_RS08010	COG0762	integral membrane protein
EQ030_RS08015	COG1799	cell septum assembly
EQ030_RS08020	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
EQ030_RS08025	COG1496	oxidoreductase activity
EQ030_RS08030	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
EQ030_RS08035	COG0849	cell division
EQ030_RS08040	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
EQ030_RS08045	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
EQ030_RS08050	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EQ030_RS08055	COG0768	penicillin binding
EQ030_RS08060	COG4839	cell division protein FtsL
EQ030_RS08065	COG0275	rRNA processing
EQ030_RS08070	COG2001	Belongs to the MraZ family
EQ030_RS08075	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
EQ030_RS08080	COG0454	-acetyltransferase
EQ030_RS08085	COG1011	Hydrolase
EQ030_RS08110	COG1280	lysine exporter protein (LysE YggA)
EQ030_RS08125	COG2801	Transposase and inactivated derivatives
EQ030_RS08180	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
EQ030_RS08185	COG1733	regulation of RNA biosynthetic process
EQ030_RS08190	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EQ030_RS08195	COG0697	spore germination
EQ030_RS08200	COG1063	alcohol dehydrogenase
EQ030_RS08205	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EQ030_RS08205	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EQ030_RS08210	COG0693	protein deglycase activity
EQ030_RS08215	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
EQ030_RS08220	COG4221	oxidoreductase activity
EQ030_RS08225	COG1733	regulation of RNA biosynthetic process
EQ030_RS08230	COG1012	belongs to the aldehyde dehydrogenase family
EQ030_RS08235	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
EQ030_RS08245	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EQ030_RS08250	COG1063	alcohol dehydrogenase
EQ030_RS08255	COG1846	Transcriptional regulator
EQ030_RS08260	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EQ030_RS08290	COG0582	viral genome integration into host DNA
EQ030_RS08310	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
EQ030_RS08315	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
EQ030_RS08320	COG1053	succinate dehydrogenase
EQ030_RS08325	COG2009	succinate dehydrogenase
EQ030_RS08330	COG0322	excinuclease ABC activity
EQ030_RS08335	COG3118	belongs to the thioredoxin family
EQ030_RS08340	COG1193	negative regulation of DNA recombination
EQ030_RS08345	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
EQ030_RS08345	COG1796	DNA polymerase
EQ030_RS08355	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
EQ030_RS08360	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EQ030_RS08365	COG0072	phenylalanine-tRNA ligase activity
EQ030_RS08370	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
EQ030_RS08375	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EQ030_RS08385	COG0333	Belongs to the bacterial ribosomal protein bL32 family
EQ030_RS08400	COG1323	Belongs to the UPF0348 family
EQ030_RS08405	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
EQ030_RS08410	COG0742	ribosomal rna small subunit methyltransferase
EQ030_RS08425	COG0584	glycerophosphoryl diester phosphodiesterase
EQ030_RS08430	COG3679	Belongs to the UPF0342 family
EQ030_RS08450	COG0109	protoheme IX farnesyltransferase activity
EQ030_RS08455	COG1612	heme a metabolic process
EQ030_RS08465	COG0772	Belongs to the SEDS family
EQ030_RS08470	COG4838	Belongs to the UPF0358 family
EQ030_RS08475	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
EQ030_RS08480	COG4896	Protein conserved in bacteria
EQ030_RS08485	COG1217	gtp-binding protein TYPA
EQ030_RS08495	COG0483	inositol monophosphate 1-phosphatase activity
EQ030_RS08500	COG4493	Belongs to the UPF0637 family
EQ030_RS08510	COG1914	H( )-stimulated, divalent metal cation uptake system
EQ030_RS08525	COG1177	transmembrane transport
EQ030_RS08530	COG1176	ABC-type spermidine putrescine transport system, permease component I
EQ030_RS08535	COG3842	ATPase activity
EQ030_RS08545	COG4476	Belongs to the UPF0223 family
EQ030_RS08585	COG5503	Protein of unknown function (DUF1447)
EQ030_RS08590	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EQ030_RS08600	COG0569	domain protein
EQ030_RS08605	COG1294	oxidase, subunit
EQ030_RS08610	COG1271	oxidase subunit
EQ030_RS08625	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EQ030_RS08635	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
EQ030_RS08650	COG4172	Belongs to the ABC transporter superfamily
EQ030_RS08655	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EQ030_RS08660	COG0151	Belongs to the GarS family
EQ030_RS08665	COG0138	bifunctional purine biosynthesis protein purh
EQ030_RS08675	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
EQ030_RS08685	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EQ030_RS08690	COG0047	phosphoribosylformylglycinamidine synthase activity
EQ030_RS08695	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EQ030_RS08700	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
EQ030_RS08705	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
EQ030_RS08710	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
EQ030_RS08715	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
EQ030_RS08720	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EQ030_RS08720	COG1017	nitric oxide dioxygenase activity
EQ030_RS08730	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
EQ030_RS08735	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EQ030_RS08740	COG1845	cytochrome c oxidase, subunit III
EQ030_RS08745	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
EQ030_RS08755	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EQ030_RS08760	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EQ030_RS08765	COG1316	TRANSCRIPTIONal
EQ030_RS08790	COG3594	Acyltransferase
EQ030_RS08795	COG0436	Aminotransferase
EQ030_RS08805	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
EQ030_RS08815	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
EQ030_RS08820	COG1169	isochorismate synthase
EQ030_RS08825	COG1575	Belongs to the MenA family. Type 1 subfamily
EQ030_RS08835	COG2314	TM2 domain
EQ030_RS08840	COG1764	response to oxidative stress
EQ030_RS08855	COG4903	ComK protein
EQ030_RS08870	COG4873	Protein conserved in bacteria
EQ030_RS08880	COG0737	Belongs to the 5'-nucleotidase family
EQ030_RS08885	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EQ030_RS08890	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EQ030_RS08895	COG0861	Integral membrane protein TerC family
EQ030_RS08900	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
EQ030_RS08910	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EQ030_RS08915	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
EQ030_RS08920	COG2814	Major facilitator Superfamily
EQ030_RS08925	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
EQ030_RS08930	COG2382	esterase
EQ030_RS08935	COG1115	amino acid carrier protein
EQ030_RS08940	COG0628	permease
EQ030_RS08950	COG0569	domain protein
EQ030_RS08950	COG0475	glutathione-regulated potassium exporter activity
EQ030_RS08955	COG2239	Acts as a magnesium transporter
EQ030_RS08960	COG0564	pseudouridine synthase activity
EQ030_RS08965	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
EQ030_RS08970	COG2357	RelA SpoT domain protein
EQ030_RS08980	COG4116	CYTH
EQ030_RS08985	COG2346	COG2346, Truncated hemoglobins
EQ030_RS08990	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
EQ030_RS08995	COG2910	NAD(P)H-binding
EQ030_RS09000	COG1164	Oligoendopeptidase f
EQ030_RS09010	COG4862	establishment of competence for transformation
EQ030_RS09015	COG1393	Belongs to the ArsC family
EQ030_RS09020	COG0180	Tryptophanyl-tRNA synthetase
EQ030_RS09025	COG4166	transmembrane transport
EQ030_RS09030	COG4608	Belongs to the ABC transporter superfamily
EQ030_RS09035	COG0444	Belongs to the ABC transporter superfamily
EQ030_RS09040	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EQ030_RS09045	COG0601	transmembrane transport
EQ030_RS09065	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EQ030_RS09075	COG0542	response to heat
EQ030_RS09090	COG0561	phosphatase activity
EQ030_RS09095	COG0446	pyridine nucleotide-disulphide oxidoreductase
EQ030_RS09105	COG0179	Fumarylacetoacetate (FAA) hydrolase
EQ030_RS09110	COG2311	Membrane
EQ030_RS09115	COG1074	ATP-dependent DNA helicase activity
EQ030_RS09120	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
EQ030_RS09135	COG0398	Pfam SNARE associated Golgi protein
EQ030_RS09140	COG0166	Belongs to the GPI family
EQ030_RS09145	COG0137	argininosuccinate synthase activity
EQ030_RS09150	COG0165	Argininosuccinate lyase
EQ030_RS09155	COG0584	glycerophosphoryl diester phosphodiesterase
EQ030_RS09165	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EQ030_RS09170	COG1902	pentaerythritol trinitrate reductase activity
EQ030_RS09175	COG1098	S1 RNA binding domain
EQ030_RS09180	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EQ030_RS09190	COG2111	Na H antiporter
EQ030_RS09190	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EQ030_RS09195	COG2111	Na H antiporter
EQ030_RS09200	COG1006	Multisubunit Na H antiporter MnhC subunit
EQ030_RS09205	COG0651	ATP synthesis coupled electron transport
EQ030_RS09210	COG1863	multisubunit Na H antiporter MnhE subunit
EQ030_RS09215	COG2212	antiporter activity
EQ030_RS09220	COG1320	monovalent cation:proton antiporter activity
EQ030_RS09230	COG2050	protein possibly involved in aromatic compounds catabolism
EQ030_RS09235	COG2056	Na+-H+ antiporter family
EQ030_RS09240	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
EQ030_RS09245	COG1252	NADH dehydrogenase
EQ030_RS09250	COG0316	Belongs to the HesB IscA family
EQ030_RS09255	COG4844	belongs to the
EQ030_RS09260	COG1252	NADH dehydrogenase
EQ030_RS09265	COG4837	Protein of unknown function (DUF1462)
EQ030_RS09270	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
EQ030_RS09275	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
EQ030_RS09280	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EQ030_RS09285	COG1696	Membrane protein involved in D-alanine export
EQ030_RS09290	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EQ030_RS09305	COG0647	UMP catabolic process
EQ030_RS09310	COG2445	Protein of unknown function DUF86
EQ030_RS09320	COG4470	Protein conserved in bacteria
EQ030_RS09325	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
EQ030_RS09330	COG0737	Belongs to the 5'-nucleotidase family
EQ030_RS09335	COG0730	response to heat
EQ030_RS09340	COG1801	Protein of unknown function DUF72
EQ030_RS09345	COG2070	2-Nitropropane dioxygenase
EQ030_RS09350	COG1253	flavin adenine dinucleotide binding
EQ030_RS09360	COG0719	Fe-S assembly protein
EQ030_RS09365	COG0822	iron-sulfur transferase activity
EQ030_RS09370	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EQ030_RS09375	COG0719	Fe-S assembly protein
EQ030_RS09380	COG0396	ATPase activity
EQ030_RS09390	COG1253	flavin adenine dinucleotide binding
EQ030_RS09400	COG1464	Belongs to the NlpA lipoprotein family
EQ030_RS09405	COG2011	ABC-type metal ion transport system permease component
EQ030_RS09410	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
EQ030_RS09415	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EQ030_RS09420	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
EQ030_RS09425	COG0509	glycine decarboxylation via glycine cleavage system
EQ030_RS09430	COG1393	Belongs to the ArsC family
EQ030_RS09435	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EQ030_RS09440	COG0778	Nitroreductase
EQ030_RS09445	COG0710	3-dehydroquinate dehydratase activity
EQ030_RS09450	COG1764	response to oxidative stress
EQ030_RS09465	COG2851	Citrate transporter
EQ030_RS09480	COG2314	TM2 domain
EQ030_RS09520	COG0346	lactoylglutathione lyase activity
EQ030_RS09570	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EQ030_RS09575	COG0546	phosphoglycolate phosphatase activity
EQ030_RS09590	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
EQ030_RS09595	COG0557	exoribonuclease II activity
EQ030_RS09600	COG1647	Serine aminopeptidase, S33
EQ030_RS09605	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EQ030_RS09615	COG0148	phosphopyruvate hydratase activity
EQ030_RS09620	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
EQ030_RS09625	COG0149	triose-phosphate isomerase activity
EQ030_RS09630	COG0126	phosphoglycerate kinase activity
EQ030_RS09655	COG1090	epimerase
EQ030_RS09665	COG0740	serine-type endopeptidase activity
EQ030_RS09680	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EQ030_RS09685	COG1481	regulation of sporulation
EQ030_RS09690	COG0391	Required for morphogenesis under gluconeogenic growth conditions
EQ030_RS09695	COG1660	Displays ATPase and GTPase activities
EQ030_RS09700	COG0492	ferredoxin-NADP+ reductase activity
EQ030_RS09710	COG0110	maltose O-acetyltransferase activity
EQ030_RS09715	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
EQ030_RS09720	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
EQ030_RS09730	COG0556	nucleotide-excision repair
EQ030_RS09745	COG1388	LysM domain
EQ030_RS09745	COG3942	CHAP domain
EQ030_RS09755	COG0653	protein targeting
EQ030_RS09760	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
EQ030_RS09765	COG1040	competence protein
EQ030_RS09770	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
EQ030_RS09780	COG1739	Uncharacterized protein family UPF0029
EQ030_RS09785	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EQ030_RS09790	COG2199	diguanylate cyclase activity
EQ030_RS09805	COG2195	Cleaves the N-terminal amino acid of tripeptides
EQ030_RS09810	COG1929	Belongs to the glycerate kinase type-1 family
EQ030_RS09830	COG0812	UDP-N-acetylmuramate dehydrogenase activity
EQ030_RS09845	COG4607	ABC-type enterochelin transport system periplasmic component
EQ030_RS09850	COG4604	ABC transporter, ATP-binding protein
EQ030_RS09855	COG4605	iron ion homeostasis
EQ030_RS09860	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EQ030_RS09865	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EQ030_RS09870	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EQ030_RS09875	COG1780	Probably involved in ribonucleotide reductase function
EQ030_RS09885	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
EQ030_RS09890	COG3104	oligopeptide transport
EQ030_RS09895	COG3104	oligopeptide transport
EQ030_RS09900	COG1597	lipid kinase activity
EQ030_RS09910	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
EQ030_RS09915	COG1174	glycine betaine transport
EQ030_RS09925	COG0514	ATP-dependent DNA helicase (RecQ)
EQ030_RS09930	COG0488	(ABC) transporter
EQ030_RS09940	COG1368	sulfuric ester hydrolase activity
EQ030_RS09950	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
EQ030_RS09965	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EQ030_RS09970	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EQ030_RS09970	COG0512	Glutamine amidotransferase of anthranilate synthase
EQ030_RS09975	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
EQ030_RS09980	COG0720	synthase
EQ030_RS09985	COG0602	queuosine metabolic process
EQ030_RS10000	COG0463	Glycosyl transferase, family 2
EQ030_RS10005	COG0656	L-ascorbic acid biosynthetic process
EQ030_RS10010	COG1253	flavin adenine dinucleotide binding
EQ030_RS10015	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
EQ030_RS10020	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EQ030_RS10020	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EQ030_RS10020	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EQ030_RS10025	COG1105	Belongs to the carbohydrate kinase PfkB family
EQ030_RS10030	COG1349	DNA-binding transcription factor activity
EQ030_RS10035	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
EQ030_RS10040	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EQ030_RS10070	COG0039	L-malate dehydrogenase activity
EQ030_RS10075	COG0586	Pfam SNARE associated Golgi protein
EQ030_RS10085	COG4989	oxidoreductase activity
EQ030_RS10100	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
EQ030_RS10105	COG4988	ABC transporter
EQ030_RS10110	COG1968	undecaprenyl-diphosphatase activity
EQ030_RS10120	COG1671	Belongs to the UPF0178 family
EQ030_RS10125	COG1611	Belongs to the LOG family
EQ030_RS10130	COG1279	arginine transmembrane transporter activity
EQ030_RS10135	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EQ030_RS10165	COG2814	Major facilitator Superfamily
EQ030_RS10170	COG2839	Protein conserved in bacteria
EQ030_RS10175	COG2814	Major facilitator Superfamily
EQ030_RS10180	COG0583	DNA-binding transcription factor activity
EQ030_RS10190	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
EQ030_RS10200	COG0217	transcriptional regulatory protein
EQ030_RS10220	COG3942	CHAP domain
EQ030_RS10220	COG1388	LysM domain
EQ030_RS10225	COG0306	phosphate transporter
EQ030_RS10230	COG1392	Phosphate transport regulator
EQ030_RS10235	COG2205	protein histidine kinase activity
EQ030_RS10240	COG0745	RESPONSE REGULATOR receiver
EQ030_RS10245	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EQ030_RS10255	COG0657	acetylesterase activity
EQ030_RS10260	COG3949	Membrane
EQ030_RS10270	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
EQ030_RS10275	COG1461	Dihydroxyacetone kinase
EQ030_RS10280	COG2376	Dihydroxyacetone kinase
EQ030_RS10285	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EQ030_RS10290	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EQ030_RS10295	COG1120	ATPase activity
EQ030_RS10300	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EQ030_RS10305	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EQ030_RS10310	COG1132	(ABC) transporter
EQ030_RS10320	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
EQ030_RS10325	COG1442	glycosyl transferase family 8
EQ030_RS10325	COG1216	Glycosyl transferase, family 2
EQ030_RS10330	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
EQ030_RS10335	COG1682	transport, permease protein
EQ030_RS10340	COG1134	teichoic acid transport
EQ030_RS10345	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
EQ030_RS10360	COG1121	(ABC) transporter
EQ030_RS10365	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EQ030_RS10370	COG0803	Belongs to the bacterial solute-binding protein 9 family
EQ030_RS10380	COG1320	monovalent cation:proton antiporter activity
EQ030_RS10385	COG2212	antiporter activity
EQ030_RS10390	COG1863	multisubunit Na H antiporter MnhE subunit
EQ030_RS10395	COG0651	ATP synthesis coupled electron transport
EQ030_RS10400	COG1006	Multisubunit Na H antiporter MnhC subunit
EQ030_RS10405	COG2111	Na H antiporter
EQ030_RS10410	COG2111	Na H antiporter
EQ030_RS10410	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EQ030_RS10450	COG0596	Alpha beta hydrolase
EQ030_RS10465	COG2267	carboxylic ester hydrolase activity
EQ030_RS10470	COG0546	phosphoglycolate phosphatase activity
EQ030_RS10475	COG4139	cobalamin transport
EQ030_RS10480	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EQ030_RS10485	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
EQ030_RS10490	COG0018	arginyl-trna synthetase
EQ030_RS10505	COG1078	dGTPase activity
EQ030_RS10510	COG0456	acetyltransferase
EQ030_RS10515	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
EQ030_RS10520	COG0667	Aldo Keto reductase
EQ030_RS10525	COG4844	belongs to the
EQ030_RS10545	COG0095	Lipoate-protein ligase
EQ030_RS10550	COG0280	phosphate acetyltransferase
EQ030_RS10555	COG3253	May function as heme-dependent peroxidase
EQ030_RS10570	COG0477	Major facilitator Superfamily
EQ030_RS10575	COG1846	Transcriptional regulator
EQ030_RS10585	COG2363	Small membrane protein
EQ030_RS10595	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
EQ030_RS10600	COG0351	phosphomethylpyrimidine kinase
EQ030_RS10615	COG0534	Mate efflux family protein
EQ030_RS10640	COG0183	Belongs to the thiolase family
EQ030_RS10645	COG0318	PFAM AMP-dependent synthetase and ligase
EQ030_RS10655	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
EQ030_RS10660	COG0363	glucosamine-6-phosphate deaminase activity
EQ030_RS10670	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EQ030_RS10675	COG1469	GTP cyclohydrolase I activity
EQ030_RS10680	COG1846	Transcriptional regulator
EQ030_RS10685	COG0431	NADPH-dependent FMN reductase
EQ030_RS10690	COG0561	phosphatase activity
EQ030_RS10700	COG1428	Deoxynucleoside kinase
EQ030_RS10705	COG1428	Deoxynucleoside kinase
EQ030_RS10715	COG0546	phosphoglycolate phosphatase activity
EQ030_RS10735	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EQ030_RS10750	COG2814	Major facilitator Superfamily
EQ030_RS10755	COG2824	Alkylphosphonate utilization operon protein PhnA
EQ030_RS10765	COG1113	amino acid transport
EQ030_RS10770	COG2040	homocysteine
EQ030_RS10775	COG0833	amino acid
EQ030_RS10785	COG0010	Belongs to the arginase family
EQ030_RS10790	COG1914	H( )-stimulated, divalent metal cation uptake system
EQ030_RS10800	COG1069	ribulokinase activity
EQ030_RS10805	COG1063	alcohol dehydrogenase
EQ030_RS10810	COG2814	Major facilitator Superfamily
EQ030_RS10815	COG1349	DNA-binding transcription factor activity
EQ030_RS10840	COG0583	DNA-binding transcription factor activity
EQ030_RS10865	COG0667	Aldo Keto reductase
EQ030_RS10875	COG3477	response to acidic pH
EQ030_RS10890	COG1682	transport, permease protein
EQ030_RS10905	COG1028	Short-chain dehydrogenase reductase Sdr
EQ030_RS10910	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
EQ030_RS10915	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
EQ030_RS10945	COG1473	amidohydrolase
EQ030_RS10950	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
EQ030_RS10955	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
EQ030_RS10960	COG0049	tRNA binding
EQ030_RS10965	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
EQ030_RS10975	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EQ030_RS10980	COG0085	RNA polymerase activity
EQ030_RS10985	COG2813	Specifically methylates the guanine in position
EQ030_RS10990	COG0222	ribosome binding
EQ030_RS10995	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
EQ030_RS11005	COG0081	regulation of translation
EQ030_RS11010	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
EQ030_RS11015	COG0250	Participates in transcription elongation, termination and antitermination
EQ030_RS11025	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EQ030_RS11040	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EQ030_RS11045	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
EQ030_RS11050	COG0215	cysteine-tRNA ligase activity
EQ030_RS11055	COG1045	serine acetyltransferase
EQ030_RS11060	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EQ030_RS11065	COG4956	integral membrane protein (PIN domain superfamily)
EQ030_RS11070	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
EQ030_RS11075	COG0542	response to heat
EQ030_RS11080	COG3869	Catalyzes the specific phosphorylation of arginine residues in
EQ030_RS11085	COG3880	PFAM UvrB UvrC protein
EQ030_RS11090	COG4463	regulation of RNA biosynthetic process
EQ030_RS11095	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EQ030_RS11100	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
EQ030_RS11105	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
EQ030_RS11110	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EQ030_RS11195	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
EQ030_RS11200	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
EQ030_RS11220	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
EQ030_RS11225	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EQ030_RS11240	COG1098	S1 RNA binding domain
EQ030_RS11250	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
EQ030_RS11255	COG3956	TIGRFAM MazG family protein
EQ030_RS11260	COG2244	polysaccharide biosynthetic process
EQ030_RS11265	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
EQ030_RS11270	COG0193	aminoacyl-tRNA hydrolase activity
EQ030_RS11275	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
EQ030_RS11280	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EQ030_RS11285	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
EQ030_RS11290	COG2088	sporulation resulting in formation of a cellular spore
EQ030_RS11295	COG0251	oxidation-reduction process
EQ030_RS11300	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EQ030_RS11305	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
EQ030_RS11310	COG4466	Protein conserved in bacteria
EQ030_RS11315	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
EQ030_RS11320	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
EQ030_RS11325	COG0084	hydrolase, TatD family'
EQ030_RS11330	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EQ030_RS11330	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EQ030_RS11335	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
EQ030_RS11340	COG2827	Endonuclease containing a URI domain
EQ030_RS11345	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
EQ030_RS11350	COG4467	Involved in initiation control of chromosome replication
EQ030_RS11355	COG1774	PSP1 C-terminal conserved region
EQ030_RS11360	COG0470	DNA polymerase III
EQ030_RS11365	COG3870	Protein conserved in bacteria
EQ030_RS11370	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
EQ030_RS11375	COG1982	Orn Lys Arg decarboxylase major
EQ030_RS11395	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
EQ030_RS11400	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
EQ030_RS11405	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
EQ030_RS11420	COG2188	Transcriptional regulator
EQ030_RS11425	COG0366	Alpha amylase catalytic
EQ030_RS11430	COG1263	PTS System
EQ030_RS11430	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EQ030_RS11440	COG0493	'glutamate synthase
EQ030_RS11445	COG0070	glutamate synthase
EQ030_RS11445	COG0069	glutamate synthase activity
EQ030_RS11445	COG0067	glutamate synthase
EQ030_RS11450	COG0583	DNA-binding transcription factor activity
EQ030_RS11465	COG0004	ammonium transporteR
EQ030_RS11470	COG0494	nUDIX hydrolase
EQ030_RS11480	COG1388	LysM domain
EQ030_RS11480	COG3942	CHAP domain
EQ030_RS11490	COG0129	dihydroxy-acid dehydratase activity
EQ030_RS11505	COG0733	neurotransmitter:sodium symporter activity
EQ030_RS11510	COG1114	Component of the transport system for branched-chain amino acids
EQ030_RS11515	COG5646	InterPro IPR014922
EQ030_RS11530	COG4195	phage-related replication protein
EQ030_RS11535	COG2807	transmembrane transport
EQ030_RS11540	COG0456	acetyltransferase
EQ030_RS11540	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EQ030_RS11545	COG2814	Major facilitator Superfamily
EQ030_RS11555	COG2814	Major facilitator Superfamily
EQ030_RS11610	COG0519	Catalyzes the synthesis of GMP from XMP
EQ030_RS11610	COG0518	GMP synthase (glutamine-hydrolyzing) activity
EQ030_RS11615	COG0516	GMP reductase activity
EQ030_RS11615	COG0517	IMP dehydrogenase activity
EQ030_RS11620	COG2233	PERMEase
EQ030_RS11625	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EQ030_RS11645	COG1823	symporter activity
EQ030_RS11655	COG0778	Nitroreductase
EQ030_RS11660	COG3620	sequence-specific DNA binding
EQ030_RS11665	COG0450	alkyl hydroperoxide reductase
EQ030_RS11670	COG3634	alkyl hydroperoxide reductase activity
EQ030_RS11705	COG1280	lysine exporter protein (LysE YggA)
EQ030_RS11735	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EQ030_RS11755	COG4195	phage-related replication protein
EQ030_RS11760	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EQ030_RS11770	COG1522	sequence-specific DNA binding
EQ030_RS11785	COG2808	Putative FMN-binding domain
EQ030_RS11825	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
EQ030_RS11835	COG0360	Binds together with S18 to 16S ribosomal RNA
EQ030_RS11845	COG0012	GTP binding
EQ030_RS11850	COG4481	Protein conserved in bacteria
EQ030_RS11855	COG0668	transmembrane transport
EQ030_RS11860	COG5609	conserved protein (DUF2294)
EQ030_RS11865	COG3002	Belongs to the UPF0753 family
EQ030_RS11870	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EQ030_RS11885	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
EQ030_RS11915	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EQ030_RS11920	COG2814	Major facilitator Superfamily
EQ030_RS11950	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
EQ030_RS11960	COG0529	Catalyzes the synthesis of activated sulfate
EQ030_RS11965	COG2046	Belongs to the sulfate adenylyltransferase family
EQ030_RS11970	COG0730	response to heat
EQ030_RS11990	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EQ030_RS11995	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
EQ030_RS12000	COG0175	sulfate reduction
EQ030_RS12015	COG1475	DNA binding
EQ030_RS12020	COG0626	cystathionine gamma-synthase activity
EQ030_RS12025	COG0626	cystathionine gamma-synthase activity
EQ030_RS12030	COG0646	methionine synthase
EQ030_RS12030	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
EQ030_RS12035	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
EQ030_RS12045	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
EQ030_RS12070	COG0183	Belongs to the thiolase family
EQ030_RS12080	COG1960	acyl-CoA dehydrogenase activity
EQ030_RS12085	COG0318	PFAM AMP-dependent synthetase and ligase
EQ030_RS12095	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EQ030_RS12105	COG0561	phosphatase activity
EQ030_RS12110	COG0531	amino acid
EQ030_RS12115	COG0656	L-ascorbic acid biosynthetic process
EQ030_RS12155	COG1966	Carbon starvation protein
EQ030_RS12160	COG1475	DNA binding
EQ030_RS12165	COG0357	Ribosomal RNA small subunit methyltransferase G
EQ030_RS12170	COG0445	tRNA wobble uridine modification
EQ030_RS12175	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
EQ030_RS12180	COG0594	ribonuclease P activity
EQ030_RS12225	COG4716	Myosin-crossreactive antigen
EQ030_RS12230	COG1063	alcohol dehydrogenase
EQ030_RS12240	COG1073	alpha beta
EQ030_RS12245	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
EQ030_RS12250	COG0753	catalase activity
EQ030_RS12260	COG1309	transcriptional regulator
EQ030_RS12280	COG0583	DNA-binding transcription factor activity
EQ030_RS12345	COG1959	2 iron, 2 sulfur cluster binding
EQ030_RS12355	COG2910	NAD(P)H-binding
EQ030_RS12360	COG0730	response to heat
EQ030_RS12365	COG1937	Protein conserved in bacteria
EQ030_RS12370	COG2210	Belongs to the sulfur carrier protein TusA family
EQ030_RS12375	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EQ030_RS12415	COG1192	Involved in chromosome partitioning
EQ030_RS12435	COG0640	Transcriptional regulator
EQ030_RS12455	COG0446	pyridine nucleotide-disulphide oxidoreductase
EQ030_RS12465	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
EQ030_RS12470	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EQ030_RS12495	COG0583	DNA-binding transcription factor activity
EQ030_RS12500	COG1607	acyl-coa hydrolase
EQ030_RS12520	COG1705	Flagellar rod assembly protein muramidase FlgJ
EQ030_RS12520	COG3942	CHAP domain
EQ030_RS12565	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
EQ030_RS12585	COG1070	Carbohydrate kinase
EQ030_RS12595	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EQ030_RS12600	COG2022	thiamine diphosphate biosynthetic process
EQ030_RS12600	COG2104	thiamine diphosphate biosynthetic process
EQ030_RS12605	COG2022	thiamine diphosphate biosynthetic process
EQ030_RS12610	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EQ030_RS12645	COG0693	protein deglycase activity
EQ030_RS12685	COG2409	Drug exporters of the RND superfamily