locus-tag	class	description
NP71_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
NP71_RS00010	COG0592	DNA-directed DNA polymerase activity
NP71_RS00020	COG2501	S4 domain
NP71_RS00030	COG0187	DNA topoisomerase II activity
NP71_RS00040	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
NP71_RS00045	COG2986	histidine ammonia-lyase
NP71_RS00055	COG2353	YceI-like domain
NP71_RS00060	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
NP71_RS00070	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
NP71_RS00075	COG4241	membrane
NP71_RS00080	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
NP71_RS00085	COG0359	binds to the 23S rRNA
NP71_RS00090	COG0305	Participates in initiation and elongation during chromosome replication
NP71_RS00095	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
NP71_RS00110	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
NP71_RS00130	COG0745	RESPONSE REGULATOR receiver
NP71_RS00135	COG5002	protein histidine kinase activity
NP71_RS00140	COG4863	YycH protein
NP71_RS00150	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
NP71_RS00160	COG0747	negative chemotaxis
NP71_RS00180	COG1124	(ABC) transporter
NP71_RS00185	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
NP71_RS00210	COG0584	glycerophosphoryl diester phosphodiesterase
NP71_RS00215	COG2030	dehydratase
NP71_RS00285	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NP71_RS00290	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NP71_RS00330	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
NP71_RS00340	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
NP71_RS00365	COG2207	Transcriptional regulator
NP71_RS00375	COG2207	Transcriptional regulator
NP71_RS00385	COG2211	Major facilitator Superfamily
NP71_RS00400	COG1136	(ABC) transporter
NP71_RS00405	COG1609	Transcriptional regulator
NP71_RS00410	COG1621	beta-fructofuranosidase activity
NP71_RS00425	COG1250	3-hydroxyacyl-CoA dehydrogenase
NP71_RS00430	COG0415	Belongs to the DNA photolyase family
NP71_RS00445	COG2376	Dihydroxyacetone kinase
NP71_RS00450	COG1461	Dihydroxyacetone kinase
NP71_RS00455	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
NP71_RS00465	COG0577	efflux transmembrane transporter activity
NP71_RS00465	COG0577	efflux transmembrane transporter activity
NP71_RS00470	COG1136	(ABC) transporter
NP71_RS00475	COG2205	protein histidine kinase activity
NP71_RS00480	COG0745	RESPONSE REGULATOR receiver
NP71_RS00500	COG0753	catalase activity
NP71_RS00505	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NP71_RS00510	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NP71_RS00515	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
NP71_RS00525	COG2423	ornithine cyclodeaminase activity
NP71_RS00530	COG4264	IucA IucC family
NP71_RS00535	COG2814	Major facilitator Superfamily
NP71_RS00540	COG4264	IucA IucC family
NP71_RS00545	COG4264	IucA IucC family
NP71_RS00555	COG0019	diaminopimelate decarboxylase activity
NP71_RS00560	COG1475	DNA binding
NP71_RS00565	COG0706	membrane insertase activity
NP71_RS00575	COG1869	D-ribose catabolic process
NP71_RS00580	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
NP71_RS00590	COG1288	antiporter activity
NP71_RS00630	COG2197	response regulator
NP71_RS00635	COG4585	Histidine kinase
NP71_RS00640	COG0842	Transport permease protein
NP71_RS00645	COG1131	(ABC) transporter
NP71_RS00695	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
NP71_RS00725	COG1695	Transcriptional regulator
NP71_RS00735	COG3477	response to acidic pH
NP71_RS00750	COG1388	LysM domain
NP71_RS00775	COG3711	transcriptional antiterminator
NP71_RS00790	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
NP71_RS00810	COG2235	arginine
NP71_RS00815	COG1438	arginine binding
NP71_RS00825	COG4716	Myosin-crossreactive antigen
NP71_RS00830	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
NP71_RS00875	COG2188	Transcriptional regulator
NP71_RS00910	COG2388	GCN5-related N-acetyl-transferase
NP71_RS00920	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NP71_RS00940	COG2723	6-phospho-beta-galactosidase activity
NP71_RS00945	COG2188	Transcriptional regulator
NP71_RS00950	COG0492	ferredoxin-NADP+ reductase activity
NP71_RS00955	COG1846	Transcriptional regulator
NP71_RS00975	COG0346	lactoylglutathione lyase activity
NP71_RS00985	COG1012	belongs to the aldehyde dehydrogenase family
NP71_RS00985	COG1454	alcohol dehydrogenase
NP71_RS00990	COG0471	metal ion transport
NP71_RS00995	COG1827	regulation of RNA biosynthetic process
NP71_RS01005	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
NP71_RS01010	COG0157	Belongs to the NadC ModD family
NP71_RS01015	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
NP71_RS01030	COG0366	Alpha amylase catalytic
NP71_RS01035	COG2188	Transcriptional regulator
NP71_RS01040	COG2222	sugar isomerase
NP71_RS01045	COG1105	Belongs to the carbohydrate kinase PfkB family
NP71_RS01050	COG3684	Belongs to the aldolase LacD family
NP71_RS01060	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NP71_RS01060	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
NP71_RS01065	COG3715	PTS system
NP71_RS01070	COG3716	PTS system mannose fructose sorbose family IID component
NP71_RS01080	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
NP71_RS01100	COG3314	Sporulation integral membrane protein YlbJ
NP71_RS01105	COG1414	Transcriptional regulator
NP71_RS01110	COG0531	amino acid
NP71_RS01135	COG1063	alcohol dehydrogenase
NP71_RS01140	COG1620	l-lactate permease
NP71_RS01145	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
NP71_RS01150	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
NP71_RS01175	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
NP71_RS01180	COG2910	NAD(P)H-binding
NP71_RS01185	COG2814	Major facilitator Superfamily
NP71_RS01190	COG1335	isochorismatase
NP71_RS01200	COG1063	alcohol dehydrogenase
NP71_RS01215	COG2318	DinB family
NP71_RS01220	COG0753	catalase activity
NP71_RS01230	COG0783	Belongs to the Dps family
NP71_RS01245	COG0436	Aminotransferase
NP71_RS01265	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NP71_RS01280	COG2814	Major facilitator Superfamily
NP71_RS01285	COG2162	N-hydroxyarylamine O-acetyltransferase activity
NP71_RS01295	COG1335	isochorismatase
NP71_RS01315	COG0431	NADPH-dependent FMN reductase
NP71_RS01325	COG4932	domain protein
NP71_RS01330	COG0456	acetyltransferase
NP71_RS01335	COG1755	Isoprenylcysteine carboxyl methyltransferase
NP71_RS01345	COG0579	oxidoreductase
NP71_RS01380	COG1073	alpha beta
NP71_RS01400	COG0438	transferase activity, transferring glycosyl groups
NP71_RS01405	COG0183	Belongs to the thiolase family
NP71_RS01410	COG1024	Enoyl-CoA hydratase
NP71_RS01410	COG1250	3-hydroxyacyl-CoA dehydrogenase
NP71_RS01415	COG1960	acyl-CoA dehydrogenase activity
NP71_RS01420	COG0318	PFAM AMP-dependent synthetase and ligase
NP71_RS01435	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
NP71_RS01445	COG1116	anion transmembrane transporter activity
NP71_RS01455	COG0563	adenylate kinase activity
NP71_RS01465	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NP71_RS01490	COG3711	transcriptional antiterminator
NP71_RS01490	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
NP71_RS01495	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
NP71_RS01505	COG3037	sugar-specific permease SgaT UlaA
NP71_RS01510	COG1328	CTP reductase activity
NP71_RS01515	COG0602	queuosine metabolic process
NP71_RS01530	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NP71_RS01535	COG1942	4-Oxalocrotonate Tautomerase
NP71_RS01550	COG0803	Belongs to the bacterial solute-binding protein 9 family
NP71_RS01550	COG3443	Belongs to the bacterial solute-binding protein 9 family
NP71_RS01560	COG3527	Alpha-acetolactate decarboxylase
NP71_RS01575	COG2207	Transcriptional regulator
NP71_RS01575	COG4753	response regulator
NP71_RS01590	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
NP71_RS01595	COG1210	Utp--glucose-1-phosphate uridylyltransferase
NP71_RS01600	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
NP71_RS01605	COG2211	Major facilitator Superfamily
NP71_RS01610	COG1957	nucleoside hydrolase
NP71_RS01620	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NP71_RS01625	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
NP71_RS01630	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
NP71_RS01635	COG2807	transmembrane transport
NP71_RS01640	COG1476	TRANSCRIPTIONal
NP71_RS01645	COG0586	Pfam SNARE associated Golgi protein
NP71_RS01660	COG1510	regulation of RNA biosynthetic process
NP71_RS01665	COG1012	belongs to the aldehyde dehydrogenase family
NP71_RS01670	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
NP71_RS01685	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
NP71_RS01690	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
NP71_RS01695	COG0131	Imidazoleglycerol-phosphate dehydratase
NP71_RS01700	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
NP71_RS01710	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
NP71_RS01715	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
NP71_RS01750	COG2376	Dihydroxyacetone kinase
NP71_RS01755	COG1461	Dihydroxyacetone kinase
NP71_RS01765	COG2824	Alkylphosphonate utilization operon protein PhnA
NP71_RS01770	COG1012	belongs to the aldehyde dehydrogenase family
NP71_RS01780	COG0596	Alpha beta hydrolase
NP71_RS01790	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
NP71_RS01790	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
NP71_RS01790	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
NP71_RS01800	COG1705	Flagellar rod assembly protein muramidase FlgJ
NP71_RS01800	COG3942	CHAP domain
NP71_RS01810	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
NP71_RS01825	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
NP71_RS01830	COG0747	negative chemotaxis
NP71_RS01855	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
NP71_RS01855	COG0463	Glycosyl transferase, family 2
NP71_RS01860	COG0438	transferase activity, transferring glycosyl groups
NP71_RS01875	COG3181	Tripartite tricarboxylate transporter family receptor
NP71_RS01880	COG0778	Nitroreductase
NP71_RS01885	COG3001	Fructosamine kinase
NP71_RS01905	COG1136	(ABC) transporter
NP71_RS01910	COG0577	efflux transmembrane transporter activity
NP71_RS01915	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
NP71_RS01925	COG4413	Urea transporter
NP71_RS01930	COG0831	urea catabolic process
NP71_RS01935	COG0832	Belongs to the urease beta subunit family
NP71_RS01940	COG0804	urea catabolic process
NP71_RS01945	COG0717	Belongs to the dCTP deaminase family
NP71_RS01950	COG0523	cobalamin synthesis protein
NP71_RS01965	COG0583	DNA-binding transcription factor activity
NP71_RS01975	COG1346	cytolysis
NP71_RS01980	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NP71_RS01985	COG4605	iron ion homeostasis
NP71_RS01990	COG4604	ABC transporter, ATP-binding protein
NP71_RS01995	COG4607	ABC-type enterochelin transport system periplasmic component
NP71_RS02010	COG0778	Nitroreductase
NP71_RS02015	COG2357	RelA SpoT domain protein
NP71_RS02025	COG3942	CHAP domain
NP71_RS02040	COG0596	Alpha beta hydrolase
NP71_RS02065	COG1028	Short-chain dehydrogenase reductase Sdr
NP71_RS02075	COG2816	NAD+ diphosphatase activity
NP71_RS02085	COG3835	regulator
NP71_RS02095	COG3961	Belongs to the TPP enzyme family
NP71_RS02100	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
NP71_RS02105	COG0512	Glutamine amidotransferase of anthranilate synthase
NP71_RS02115	COG0134	indole-3-glycerol-phosphate synthase activity
NP71_RS02120	COG0135	phosphoribosylanthranilate isomerase activity
NP71_RS02125	COG0133	tryptophan synthase activity
NP71_RS02130	COG0159	tryptophan synthase activity
NP71_RS02145	COG1132	(ABC) transporter
NP71_RS02150	COG1132	(ABC) transporter
NP71_RS02160	COG1115	amino acid carrier protein
NP71_RS02165	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
NP71_RS02170	COG2814	Major facilitator Superfamily
NP71_RS02175	COG2271	Major facilitator Superfamily
NP71_RS02180	COG3764	Sortase (surface protein transpeptidase)
NP71_RS02185	COG1929	Belongs to the glycerate kinase type-1 family
NP71_RS02190	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
NP71_RS02200	COG1174	glycine betaine transport
NP71_RS02225	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
NP71_RS02235	COG0702	epimerase
NP71_RS02250	COG1760	l-serine dehydratase
NP71_RS02255	COG1760	l-serine dehydratase
NP71_RS02285	COG0471	metal ion transport
NP71_RS02300	COG0454	-acetyltransferase
NP71_RS02315	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
NP71_RS02320	COG2146	nitrite reductase [NAD(P)H] activity
NP71_RS02325	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
NP71_RS02325	COG1648	precorrin-2 dehydrogenase activity
NP71_RS02330	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
NP71_RS02335	COG1140	nitrate reductase beta subunit
NP71_RS02345	COG2181	nitrate reductase activity
NP71_RS02355	COG4585	Histidine kinase
NP71_RS02360	COG2197	response regulator
NP71_RS02370	COG2223	nitrite transmembrane transporter activity
NP71_RS02380	COG0039	L-malate dehydrogenase activity
NP71_RS02385	COG1363	Peptidase, m42
NP71_RS02400	COG2807	transmembrane transport
NP71_RS02420	COG1283	sodium-dependent phosphate transmembrane transporter activity
NP71_RS02440	COG0456	acetyltransferase
NP71_RS02445	COG2814	Major facilitator Superfamily
NP71_RS02450	COG0604	alcohol dehydrogenase
NP71_RS02460	COG1620	l-lactate permease
NP71_RS02470	COG0438	transferase activity, transferring glycosyl groups
NP71_RS02520	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
NP71_RS02530	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NP71_RS02550	COG1304	FMN binding
NP71_RS02555	COG0523	cobalamin synthesis protein
NP71_RS02560	COG0786	glutamate:sodium symporter activity
NP71_RS02565	COG2207	Transcriptional regulator
NP71_RS02575	COG1695	Transcriptional regulator
NP71_RS02590	COG1757	Na H antiporter
NP71_RS02595	COG2094	Belongs to the DNA glycosylase MPG family
NP71_RS02605	COG1288	antiporter activity
NP71_RS02610	COG4152	abc transporter atp-binding protein
NP71_RS02615	COG1668	transmembrane transport
NP71_RS02620	COG1742	UPF0060 membrane protein
NP71_RS02625	COG2017	converts alpha-aldose to the beta-anomer
NP71_RS02630	COG1476	TRANSCRIPTIONal
NP71_RS02635	COG2258	MOSC domain
NP71_RS02640	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
NP71_RS02645	COG1266	CAAX protease self-immunity
NP71_RS02650	COG0010	Belongs to the arginase family
NP71_RS02655	COG0583	DNA-binding transcription factor activity
NP71_RS02660	COG3314	Sporulation integral membrane protein YlbJ
NP71_RS02670	COG1228	amidohydrolase
NP71_RS02675	COG0659	secondary active sulfate transmembrane transporter activity
NP71_RS02680	COG1473	amidohydrolase
NP71_RS02700	COG0385	Bile acid
NP71_RS02730	COG1113	amino acid transport
NP71_RS02755	COG1316	TRANSCRIPTIONal
NP71_RS02770	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
NP71_RS02775	COG3383	formate dehydrogenase (NAD+) activity
NP71_RS02800	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NP71_RS02805	COG2076	Multidrug Resistance protein
NP71_RS02810	COG2076	Multidrug Resistance protein
NP71_RS02825	COG1757	Na H antiporter
NP71_RS02835	COG3942	CHAP domain
NP71_RS02855	COG1960	acyl-CoA dehydrogenase activity
NP71_RS02860	COG2832	Protein of unknown function (DUF454)
NP71_RS02865	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
NP71_RS02870	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NP71_RS02880	COG2186	Transcriptional regulator
NP71_RS02885	COG1940	carbohydrate kinase activity
NP71_RS02890	COG1268	BioY protein
NP71_RS02905	COG1609	Transcriptional regulator
NP71_RS02910	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
NP71_RS02915	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
NP71_RS02920	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
NP71_RS02925	COG0725	ABC transporter, periplasmic molybdate-binding protein
NP71_RS02930	COG4149	molybdate abc transporter
NP71_RS02935	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
NP71_RS02940	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
NP71_RS02945	COG0521	Mo-molybdopterin cofactor biosynthetic process
NP71_RS02950	COG0315	cyclic pyranopterin monophosphate synthase activity
NP71_RS02965	COG0314	molybdopterin synthase activity
NP71_RS02975	COG0746	molybdenum cofactor guanylyltransferase activity
NP71_RS02980	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
NP71_RS03005	COG2348	transferase activity, transferring amino-acyl groups
NP71_RS03010	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NP71_RS03015	COG0436	Aminotransferase
NP71_RS03040	COG2252	PERMEase
NP71_RS03055	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
NP71_RS03060	COG0088	Forms part of the polypeptide exit tunnel
NP71_RS03065	COG0089	rRNA binding
NP71_RS03070	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
NP71_RS03075	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
NP71_RS03080	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
NP71_RS03085	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
NP71_RS03095	COG0255	Belongs to the universal ribosomal protein uL29 family
NP71_RS03105	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
NP71_RS03110	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
NP71_RS03115	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
NP71_RS03120	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NP71_RS03125	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
NP71_RS03145	COG1841	ribosomal large subunit assembly
NP71_RS03155	COG0201	protein transport
NP71_RS03170	COG0257	Belongs to the bacterial ribosomal protein bL36 family
NP71_RS03180	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
NP71_RS03185	COG0202	RNA polymerase activity
NP71_RS03190	COG0203	ribosomal protein L17
NP71_RS03195	COG1122	ATPase activity
NP71_RS03200	COG1122	ATPase activity
NP71_RS03210	COG0101	tRNA pseudouridine synthase activity
NP71_RS03220	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
NP71_RS03250	COG0018	arginyl-trna synthetase
NP71_RS03260	COG0789	Transcriptional regulator
NP71_RS03265	COG1335	isochorismatase
NP71_RS03270	COG0488	(ABC) transporter
NP71_RS03275	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NP71_RS03280	COG0604	alcohol dehydrogenase
NP71_RS03285	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
NP71_RS03300	COG1302	Protein conserved in bacteria
NP71_RS03305	COG2814	Major facilitator Superfamily
NP71_RS03310	COG4264	IucA IucC family
NP71_RS03315	COG2814	Major facilitator Superfamily
NP71_RS03320	COG4264	IucA IucC family
NP71_RS03325	COG3457	Alanine racemase
NP71_RS03330	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
NP71_RS03340	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NP71_RS03345	COG3314	Sporulation integral membrane protein YlbJ
NP71_RS03355	COG1988	membrane-bound metal-dependent
NP71_RS03360	COG4284	Utp--glucose-1-phosphate uridylyltransferase
NP71_RS03365	COG1272	protein, Hemolysin III
NP71_RS03385	COG2814	Major facilitator Superfamily
NP71_RS03390	COG0489	protein tyrosine kinase activity
NP71_RS03455	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NP71_RS03475	COG2186	Transcriptional regulator
NP71_RS03480	COG1482	cell wall glycoprotein biosynthetic process
NP71_RS03505	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
NP71_RS03535	COG5146	pantothenate kinase activity
NP71_RS03545	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NP71_RS03560	COG2271	Major facilitator Superfamily
NP71_RS03565	COG4821	SIS domain
NP71_RS03570	COG0191	fructose-bisphosphate aldolase activity
NP71_RS03575	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NP71_RS03580	COG1733	regulation of RNA biosynthetic process
NP71_RS03590	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
NP71_RS03595	COG0254	rRNA binding
NP71_RS03605	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
NP71_RS03610	COG2890	protein-(glutamine-N5) methyltransferase activity
NP71_RS03615	COG0009	L-threonylcarbamoyladenylate synthase
NP71_RS03620	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NP71_RS03625	COG4475	Protein of unknown function (DUF436)
NP71_RS03630	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
NP71_RS03635	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
NP71_RS03640	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
NP71_RS03650	COG0356	it plays a direct role in the translocation of protons across the membrane
NP71_RS03655	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NP71_RS03665	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NP71_RS03670	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
NP71_RS03675	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
NP71_RS03695	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NP71_RS03705	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
NP71_RS03720	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
NP71_RS03730	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
NP71_RS03735	COG0352	thiamine-phosphate diphosphorylase activity
NP71_RS03740	COG0706	membrane insertase activity
NP71_RS03755	COG1418	mRNA catabolic process
NP71_RS03765	COG1937	Protein conserved in bacteria
NP71_RS03780	COG2217	Heavy metal translocating P-type atpase
NP71_RS03785	COG0772	Belongs to the SEDS family
NP71_RS03790	COG1181	Belongs to the D-alanine--D-alanine ligase family
NP71_RS03795	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
NP71_RS03800	COG0513	Belongs to the DEAD box helicase family
NP71_RS03820	COG0736	holo-[acyl-carrier-protein] synthase activity
NP71_RS03825	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NP71_RS03835	COG2337	Toxic component of a toxin-antitoxin (TA) module
NP71_RS03840	COG2208	phosphoserine phosphatase activity
NP71_RS03845	COG1366	Belongs to the anti-sigma-factor antagonist family
NP71_RS03855	COG1191	sigma factor activity
NP71_RS03860	COG2183	response to ionizing radiation
NP71_RS03865	COG3091	SprT-like family
NP71_RS03895	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
NP71_RS03905	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
NP71_RS03915	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
NP71_RS03930	COG0028	Belongs to the TPP enzyme family
NP71_RS03935	COG0129	dihydroxy-acid dehydratase activity
NP71_RS03940	COG0802	atpase or kinase
NP71_RS03945	COG1214	PFAM Peptidase M22, glycoprotease
NP71_RS03950	COG0456	acetyltransferase
NP71_RS03955	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
NP71_RS03960	COG0488	(ABC) transporter
NP71_RS03965	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
NP71_RS03970	COG2391	methyltransferase activity
NP71_RS03975	COG0425	Belongs to the sulfur carrier protein TusA family
NP71_RS03980	COG1621	beta-fructofuranosidase activity
NP71_RS04000	COG4512	PFAM Accessory gene regulator B
NP71_RS04060	COG1464	Belongs to the NlpA lipoprotein family
NP71_RS04065	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
NP71_RS04085	COG1131	(ABC) transporter
NP71_RS04095	COG1802	Transcriptional regulator
NP71_RS04100	COG1070	Carbohydrate kinase
NP71_RS04105	COG2610	gluconate transmembrane transporter activity
NP71_RS04140	COG2706	6-phosphogluconolactonase activity
NP71_RS04145	COG1012	belongs to the aldehyde dehydrogenase family
NP71_RS04155	COG1227	inorganic diphosphatase activity
NP71_RS04160	COG1335	isochorismatase
NP71_RS04170	COG0077	Prephenate dehydratase
NP71_RS04180	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
NP71_RS04185	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
NP71_RS04190	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
NP71_RS04195	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
NP71_RS04200	COG4496	protein, YerC YecD
NP71_RS04205	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
NP71_RS04210	COG0210	DNA helicase
NP71_RS04215	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
NP71_RS04220	COG4851	CamS sex pheromone cAM373 precursor
NP71_RS04225	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NP71_RS04230	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NP71_RS04235	COG0154	amidase activity
NP71_RS04240	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NP71_RS04250	COG1597	lipid kinase activity
NP71_RS04255	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NP71_RS04270	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NP71_RS04280	COG1528	Iron-storage protein
NP71_RS04295	COG4129	membrane
NP71_RS04300	COG0024	Methionine aminopeptidase
NP71_RS04325	COG0288	reversible hydration of carbon dioxide
NP71_RS04330	COG1295	ribonuclease BN
NP71_RS04340	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NP71_RS04345	COG4840	Belongs to the UPF0435 family
NP71_RS04350	COG2309	aminopeptidase activity
NP71_RS04355	COG1607	acyl-coa hydrolase
NP71_RS04360	COG0535	radical SAM domain protein
NP71_RS04365	COG0693	protein deglycase activity
NP71_RS04370	COG0028	Belongs to the TPP enzyme family
NP71_RS04375	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
NP71_RS04380	COG2137	regulation of response to DNA damage stimulus
NP71_RS04390	COG1134	teichoic acid transport
NP71_RS04390	COG1388	LysM domain
NP71_RS04400	COG1988	membrane-bound metal-dependent
NP71_RS04420	COG0069	glutamate synthase activity
NP71_RS04425	COG4129	membrane
NP71_RS04430	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
NP71_RS04435	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
NP71_RS04445	COG0735	belongs to the Fur family
NP71_RS04595	COG1181	Belongs to the D-alanine--D-alanine ligase family
NP71_RS04605	COG0765	amino acid transport
NP71_RS04610	COG1126	abc transporter atp-binding protein
NP71_RS04615	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
NP71_RS04625	COG0363	glucosamine-6-phosphate deaminase activity
NP71_RS04635	COG0114	fumarate hydratase activity
NP71_RS04640	COG0248	Ppx GppA phosphatase
NP71_RS04645	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
NP71_RS04650	COG0564	pseudouridine synthase activity
NP71_RS04655	COG4585	Histidine kinase
NP71_RS04655	COG2203	Gaf domain
NP71_RS04660	COG2197	response regulator
NP71_RS04665	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NP71_RS04690	COG4399	Belongs to the UPF0754 family
NP71_RS04695	COG3679	Belongs to the UPF0342 family
NP71_RS04700	COG0420	3'-5' exonuclease activity
NP71_RS04710	COG3481	metal-dependent phosphohydrolase, HD sub domain
NP71_RS04715	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
NP71_RS04725	COG1846	Transcriptional regulator
NP71_RS04735	COG0537	adenosine 5'-monophosphoramidase activity
NP71_RS04740	COG1131	(ABC) transporter
NP71_RS04745	COG4473	ABC transporter
NP71_RS04755	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
NP71_RS04760	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
NP71_RS04765	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
NP71_RS04770	COG3545	Serine hydrolase
NP71_RS04865	COG0076	glutamate decarboxylase activity
NP71_RS04885	COG0318	PFAM AMP-dependent synthetase and ligase
NP71_RS04895	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
NP71_RS04905	COG1506	peptidase
NP71_RS04910	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
NP71_RS04915	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
NP71_RS04925	COG0656	L-ascorbic acid biosynthetic process
NP71_RS04930	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NP71_RS04945	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
NP71_RS04970	COG3266	domain, Protein
NP71_RS04970	COG4193	domain, Protein
NP71_RS04970	COG5632	N-Acetylmuramoyl-L-alanine amidase
NP71_RS04985	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NP71_RS04985	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NP71_RS04995	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
NP71_RS04995	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
NP71_RS05000	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
NP71_RS05005	COG0506	proline dehydrogenase activity
NP71_RS05015	COG2267	carboxylic ester hydrolase activity
NP71_RS05020	COG0039	L-malate dehydrogenase activity
NP71_RS05030	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
NP71_RS05035	COG1242	4 iron, 4 sulfur cluster binding
NP71_RS05040	COG2814	Major facilitator Superfamily
NP71_RS05045	COG0495	leucyl-tRNA aminoacylation
NP71_RS05050	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NP71_RS05055	COG2081	HI0933 family
NP71_RS05060	COG2244	polysaccharide biosynthetic process
NP71_RS05065	COG1187	pseudouridine synthase activity
NP71_RS05075	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
NP71_RS05080	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
NP71_RS05085	COG0510	thiamine kinase activity
NP71_RS05090	COG0220	tRNA (guanine-N7-)-methyltransferase activity
NP71_RS05095	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NP71_RS05105	COG1363	Peptidase, m42
NP71_RS05110	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NP71_RS05120	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NP71_RS05125	COG1674	ftsk spoiiie
NP71_RS05130	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
NP71_RS05135	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
NP71_RS05145	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
NP71_RS05145	COG1605	Chorismate mutase
NP71_RS05150	COG1609	Transcriptional regulator
NP71_RS05160	COG0454	-acetyltransferase
NP71_RS05165	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
NP71_RS05170	COG2759	Belongs to the formate--tetrahydrofolate ligase family
NP71_RS05175	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
NP71_RS05185	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NP71_RS05200	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
NP71_RS05205	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
NP71_RS05210	COG1764	response to oxidative stress
NP71_RS05215	COG0584	glycerophosphoryl diester phosphodiesterase
NP71_RS05225	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
NP71_RS05230	COG1956	GAF domain-containing protein
NP71_RS05235	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
NP71_RS05240	COG1104	cysteine desulfurase activity
NP71_RS05245	COG0301	tRNA thio-modification
NP71_RS05255	COG0616	signal peptide processing
NP71_RS05265	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
NP71_RS05270	COG0827	DNA restriction-modification system
NP71_RS05275	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NP71_RS05280	COG0589	response to stress
NP71_RS05285	COG0686	Belongs to the AlaDH PNT family
NP71_RS05295	COG0006	proline dipeptidase activity
NP71_RS05300	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
NP71_RS05310	COG4109	DRTGG domain
NP71_RS05315	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
NP71_RS05325	COG0281	malic enzyme
NP71_RS05330	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
NP71_RS05335	COG0825	malonyl-CoA metabolic process
NP71_RS05340	COG0205	6-phosphofructokinase activity
NP71_RS05345	COG0469	pyruvate kinase activity
NP71_RS05350	COG0372	Belongs to the citrate synthase family
NP71_RS05355	COG0538	isocitrate dehydrogenase activity
NP71_RS05360	COG0745	RESPONSE REGULATOR receiver
NP71_RS05365	COG5002	protein histidine kinase activity
NP71_RS05370	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NP71_RS05370	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NP71_RS05375	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
NP71_RS05380	COG0237	dephospho-CoA kinase activity
NP71_RS05385	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
NP71_RS05390	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
NP71_RS05395	COG3611	Membrane attachment protein
NP71_RS05400	COG1484	DNA-dependent DNA replication
NP71_RS05410	COG0833	amino acid
NP71_RS05415	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
NP71_RS05420	COG0291	Belongs to the bacterial ribosomal protein bL35 family
NP71_RS05430	COG4112	unkown
NP71_RS05440	COG0544	peptidyl-prolyl cis-trans isomerase activity
NP71_RS05445	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
NP71_RS05450	COG0218	Necessary for normal cell division and for the maintenance of normal septation
NP71_RS05455	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
NP71_RS05460	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
NP71_RS05465	COG0181	hydroxymethylbilane synthase activity
NP71_RS05475	COG0113	porphobilinogen synthase activity
NP71_RS05480	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
NP71_RS05490	COG2818	Glycosylase
NP71_RS05495	COG0525	valine-tRNA ligase activity
NP71_RS05500	COG0285	dihydrofolate synthase activity
NP71_RS05510	COG2003	Belongs to the UPF0758 family
NP71_RS05530	COG0261	This protein binds to 23S rRNA in the presence of protein L20
NP71_RS05535	COG2868	ribosomal protein
NP71_RS05550	COG4492	Belongs to the UPF0735 family
NP71_RS05555	COG0632	four-way junction helicase activity
NP71_RS05560	COG2255	four-way junction helicase activity
NP71_RS05565	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
NP71_RS05575	COG1862	Preprotein translocase
NP71_RS05580	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
NP71_RS05580	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
NP71_RS05585	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
NP71_RS05585	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
NP71_RS05590	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NP71_RS05600	COG1490	D-aminoacyl-tRNA deacylase activity
NP71_RS05605	COG0860	N-Acetylmuramoyl-L-alanine amidase
NP71_RS05615	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
NP71_RS05620	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
NP71_RS05625	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
NP71_RS05630	COG1959	2 iron, 2 sulfur cluster binding
NP71_RS05645	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NP71_RS05650	COG1104	cysteine desulfurase activity
NP71_RS05655	COG0482	sulfurtransferase activity
NP71_RS05665	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
NP71_RS05670	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NP71_RS05675	COG4472	Bacterial protein of unknown function (DUF965)
NP71_RS05680	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
NP71_RS05685	COG3906	Belongs to the UPF0473 family
NP71_RS05690	COG4122	O-methyltransferase activity
NP71_RS05695	COG0826	peptidase U32
NP71_RS05700	COG0826	peptidase U32
NP71_RS05705	COG0572	uridine kinase
NP71_RS05715	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
NP71_RS05720	COG1984	allophanate hydrolase subunit 2
NP71_RS05725	COG0511	ligase activity, forming carbon-carbon bonds
NP71_RS05730	COG0439	Biotin carboxylase
NP71_RS05735	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
NP71_RS05740	COG1914	H( )-stimulated, divalent metal cation uptake system
NP71_RS05755	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
NP71_RS05760	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
NP71_RS05765	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
NP71_RS05770	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
NP71_RS05775	COG1534	Rna-binding protein
NP71_RS05785	COG1713	HD superfamily hydrolase involved in NAD metabolism
NP71_RS05790	COG0799	negative regulation of ribosome biogenesis
NP71_RS05795	COG2226	methyltransferase
NP71_RS05800	COG1555	photosystem II stabilization
NP71_RS05800	COG1596	polysaccharide export
NP71_RS05805	COG2131	deaminase
NP71_RS05815	COG1466	dna polymerase III delta subunit
NP71_RS05820	COG0268	Binds directly to 16S ribosomal RNA
NP71_RS05830	COG0635	Involved in the biosynthesis of porphyrin-containing compound
NP71_RS05835	COG1420	regulation of RNA biosynthetic process
NP71_RS05850	COG0484	heat shock protein binding
NP71_RS05855	COG2264	protein methyltransferase activity
NP71_RS05860	COG1385	rRNA (uridine-N3-)-methyltransferase activity
NP71_RS05865	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
NP71_RS05880	COG4864	UPF0365 protein
NP71_RS05890	COG1702	phosphate starvation-inducible protein PhoH
NP71_RS05895	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
NP71_RS05900	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
NP71_RS05905	COG0295	cytidine deaminase activity
NP71_RS05915	COG1381	Involved in DNA repair and RecF pathway recombination
NP71_RS05920	COG0423	glycine-tRNA ligase activity
NP71_RS05925	COG0517	IMP dehydrogenase activity
NP71_RS05930	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
NP71_RS05935	COG0358	DNA primase activity
NP71_RS05940	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NP71_RS05945	COG2384	SAM-dependent methyltransferase
NP71_RS05955	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
NP71_RS05960	COG0513	Belongs to the DEAD box helicase family
NP71_RS05965	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
NP71_RS05970	COG1121	(ABC) transporter
NP71_RS05975	COG1108	ABC-type Mn2 Zn2 transport systems permease components
NP71_RS05980	COG0735	belongs to the Fur family
NP71_RS05985	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
NP71_RS05995	COG0768	penicillin binding
NP71_RS06000	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
NP71_RS06005	COG0573	inorganic phosphate transmembrane transporter activity
NP71_RS06010	COG0581	inorganic phosphate transmembrane transporter activity
NP71_RS06015	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
NP71_RS06020	COG0704	Plays a role in the regulation of phosphate uptake
NP71_RS06025	COG0267	Belongs to the bacterial ribosomal protein bL33 family
NP71_RS06030	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
NP71_RS06035	COG0705	Rhomboid family
NP71_RS06035	COG0457	Tetratricopeptide repeat
NP71_RS06040	COG4483	Protein conserved in bacteria
NP71_RS06045	COG1940	carbohydrate kinase activity
NP71_RS06050	COG0011	TIGRFAM Protein of
NP71_RS06055	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NP71_RS06060	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
NP71_RS06065	COG1459	type II secretion system
NP71_RS06085	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
NP71_RS06090	COG0404	The glycine cleavage system catalyzes the degradation of glycine
NP71_RS06100	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
NP71_RS06105	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NP71_RS06110	COG0095	Lipoate-protein ligase
NP71_RS06125	COG0006	proline dipeptidase activity
NP71_RS06130	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
NP71_RS06135	COG0511	ligase activity, forming carbon-carbon bonds
NP71_RS06140	COG0439	Biotin carboxylase
NP71_RS06145	COG1302	Protein conserved in bacteria
NP71_RS06165	COG0142	geranyltranstransferase activity
NP71_RS06170	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
NP71_RS06175	COG1438	arginine binding
NP71_RS06180	COG0497	DNA recombination
NP71_RS06185	COG0280	phosphate acetyltransferase
NP71_RS06190	COG3426	butyrate kinase activity
NP71_RS06195	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NP71_RS06200	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
NP71_RS06205	COG0022	dehydrogenase e1 component
NP71_RS06210	COG0508	dehydrogenase complex catalyzes the overall conversion of
NP71_RS06220	COG4129	membrane
NP71_RS06225	COG2195	Cleaves the N-terminal amino acid of tripeptides
NP71_RS06240	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
NP71_RS06245	COG1234	tRNA 3'-trailer cleavage
NP71_RS06250	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NP71_RS06260	COG0667	Aldo Keto reductase
NP71_RS06265	COG0494	nUDIX hydrolase
NP71_RS06270	COG0735	belongs to the Fur family
NP71_RS06285	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
NP71_RS06290	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
NP71_RS06295	COG1187	pseudouridine synthase activity
NP71_RS06300	COG0745	RESPONSE REGULATOR receiver
NP71_RS06305	COG5002	protein histidine kinase activity
NP71_RS06315	COG1141	Ferredoxin
NP71_RS06325	COG0514	ATP-dependent DNA helicase (RecQ)
NP71_RS06335	COG0492	ferredoxin-NADP+ reductase activity
NP71_RS06345	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
NP71_RS06350	COG0539	negative regulation of cytoplasmic translation
NP71_RS06375	COG2226	methyltransferase
NP71_RS06380	COG0142	geranyltranstransferase activity
NP71_RS06385	COG0105	UTP biosynthetic process
NP71_RS06395	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
NP71_RS06405	COG0457	Tetratricopeptide repeat
NP71_RS06410	COG5582	Belongs to the UPF0302 family
NP71_RS06415	COG4347	Protein of unknown function (DUF1405)
NP71_RS06420	COG2738	Putative neutral zinc metallopeptidase
NP71_RS06425	COG1694	Mazg nucleotide pyrophosphohydrolase
NP71_RS06430	COG0438	transferase activity, transferring glycosyl groups
NP71_RS06445	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
NP71_RS06445	COG1199	ATP-dependent helicase activity
NP71_RS06450	COG0017	Asparaginyl-tRNA synthetase
NP71_RS06455	COG3935	DnaD domain protein
NP71_RS06460	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
NP71_RS06470	COG4499	WXG100 protein secretion system (Wss), protein YukC
NP71_RS06470	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
NP71_RS06475	COG3331	DNA recombination
NP71_RS06485	COG4474	Belongs to the UPF0398 family
NP71_RS06490	COG3599	regulation of cell shape
NP71_RS06495	COG0116	Belongs to the methyltransferase superfamily
NP71_RS06500	COG2962	Rard protein
NP71_RS06510	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NP71_RS06520	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
NP71_RS06530	COG1413	lyase activity
NP71_RS06540	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
NP71_RS06565	COG2190	(PTS) system
NP71_RS06570	COG4479	Belongs to the UPF0346 family
NP71_RS06575	COG0793	Belongs to the peptidase S41A family
NP71_RS06585	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
NP71_RS06590	COG0671	phosphoesterase, PA-phosphatase related
NP71_RS06600	COG5002	protein histidine kinase activity
NP71_RS06605	COG0567	Dehydrogenase, E1 component
NP71_RS06630	COG0714	Associated with various cellular activities
NP71_RS06635	COG4548	von Willebrand factor, type A
NP71_RS06640	COG1114	Component of the transport system for branched-chain amino acids
NP71_RS06645	COG3853	Toxic anion resistance protein (TelA)
NP71_RS06655	COG1254	Belongs to the acylphosphatase family
NP71_RS06665	COG1278	Cold shock
NP71_RS06680	COG1473	amidohydrolase
NP71_RS06685	COG2171	N-acyltransferase activity
NP71_RS06690	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
NP71_RS06695	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NP71_RS06700	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
NP71_RS06705	COG0488	(ABC) transporter
NP71_RS06710	COG2996	Protein conserved in bacteria
NP71_RS06715	COG3711	transcriptional antiterminator
NP71_RS06720	COG1447	Phosphotransferase system cellobiose-specific component IIA
NP71_RS06725	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
NP71_RS06725	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
NP71_RS06740	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
NP71_RS06800	COG0305	Participates in initiation and elongation during chromosome replication
NP71_RS06905	COG4695	Portal protein
NP71_RS06980	COG1388	LysM domain
NP71_RS06980	COG0860	N-Acetylmuramoyl-L-alanine amidase
NP71_RS07010	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
NP71_RS07010	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
NP71_RS07015	COG2723	6-phospho-beta-galactosidase activity
NP71_RS07025	COG0698	ribose 5-phosphate isomerase
NP71_RS07030	COG0698	ribose 5-phosphate isomerase
NP71_RS07060	COG1363	Peptidase, m42
NP71_RS07065	COG0287	Prephenate dehydrogenase
NP71_RS07070	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NP71_RS07100	COG0628	permease
NP71_RS07110	COG3711	transcriptional antiterminator
NP71_RS07115	COG1115	amino acid carrier protein
NP71_RS07120	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NP71_RS07125	COG0187	DNA topoisomerase II activity
NP71_RS07130	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
NP71_RS07135	COG4841	protein insertion into membrane
NP71_RS07140	COG0824	Thioesterase
NP71_RS07145	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
NP71_RS07150	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
NP71_RS07155	COG1970	mechanosensitive ion channel activity
NP71_RS07170	COG4846	Membrane protein involved in cytochrome C biogenesis
NP71_RS07180	COG3763	UPF0154 protein
NP71_RS07190	COG4224	UPF0291 protein
NP71_RS07200	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
NP71_RS07210	COG0516	GMP reductase activity
NP71_RS07225	COG0833	amino acid
NP71_RS07235	COG0561	phosphatase activity
NP71_RS07240	COG0083	homoserine kinase activity
NP71_RS07245	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
NP71_RS07250	COG0460	homoserine dehydrogenase
NP71_RS07255	COG0527	aspartate kinase activity
NP71_RS07285	COG1518	maintenance of DNA repeat elements
NP71_RS07300	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
NP71_RS07305	COG1525	nuclease
NP71_RS07325	COG1525	nuclease
NP71_RS07335	COG0584	glycerophosphoryl diester phosphodiesterase
NP71_RS07405	COG0789	Transcriptional regulator
NP71_RS07410	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
NP71_RS07420	COG0386	Belongs to the glutathione peroxidase family
NP71_RS07425	COG1923	regulation of RNA biosynthetic process
NP71_RS07430	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
NP71_RS07435	COG2267	carboxylic ester hydrolase activity
NP71_RS07440	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
NP71_RS07450	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
NP71_RS07460	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
NP71_RS07465	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
NP71_RS07470	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
NP71_RS07485	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
NP71_RS07495	COG1013	pyruvate-flavodoxin oxidoreductase activity
NP71_RS07500	COG0674	pyruvate-flavodoxin oxidoreductase activity
NP71_RS07500	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
NP71_RS07505	COG1692	metallophosphoesterase
NP71_RS07530	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
NP71_RS07535	COG1058	Belongs to the CinA family
NP71_RS07535	COG1546	Belongs to the CinA family
NP71_RS07555	COG1028	Short-chain dehydrogenase reductase Sdr
NP71_RS07560	COG0612	Peptidase, M16
NP71_RS07565	COG0612	Peptidase, M16
NP71_RS07570	COG2188	Transcriptional regulator
NP71_RS07590	COG1185	polyribonucleotide nucleotidyltransferase activity
NP71_RS07600	COG0196	riboflavin kinase activity
NP71_RS07605	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
NP71_RS07610	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
NP71_RS07615	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
NP71_RS07625	COG1131	(ABC) transporter
NP71_RS07630	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
NP71_RS07675	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
NP71_RS07680	COG1358	cellular component organization or biogenesis
NP71_RS07685	COG2740	Nucleic-acid-binding protein implicated in transcription termination
NP71_RS07690	COG0195	Participates in both transcription termination and antitermination
NP71_RS07695	COG0779	Required for maturation of 30S ribosomal subunits
NP71_RS07705	COG0442	prolyl-tRNA aminoacylation
NP71_RS07715	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
NP71_RS07720	COG4589	Belongs to the CDS family
NP71_RS07730	COG0233	cytoplasmic translational termination
NP71_RS07735	COG0528	UMP kinase activity
NP71_RS07740	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
NP71_RS07745	COG0052	Belongs to the universal ribosomal protein uS2 family
NP71_RS07750	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
NP71_RS07755	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
NP71_RS07760	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
NP71_RS07765	COG4974	Belongs to the 'phage' integrase family
NP71_RS07770	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
NP71_RS07775	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NP71_RS07780	COG0758	DNA mediated transformation
NP71_RS07790	COG0045	succinate-CoA ligase (ADP-forming) activity
NP71_RS07805	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NP71_RS07820	COG4485	Bacterial membrane protein, YfhO
NP71_RS07830	COG0335	large ribosomal subunit rRNA binding
NP71_RS07835	COG0336	Belongs to the RNA methyltransferase TrmD family
NP71_RS07845	COG0228	four-way junction DNA binding
NP71_RS07850	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
NP71_RS07855	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
NP71_RS07860	COG0552	protein localization to endoplasmic reticulum
NP71_RS07865	COG1196	nuclear chromosome segregation
NP71_RS07875	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NP71_RS07890	COG0416	fatty acid biosynthetic process
NP71_RS07895	COG1349	DNA-binding transcription factor activity
NP71_RS07905	COG1760	l-serine dehydratase
NP71_RS07910	COG1760	l-serine dehydratase
NP71_RS07915	COG1461	Dihydroxyacetone kinase
NP71_RS07920	COG1302	Protein conserved in bacteria
NP71_RS07925	COG0227	Belongs to the bacterial ribosomal protein bL28 family
NP71_RS07935	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
NP71_RS07940	COG1162	GTPase activity
NP71_RS07955	COG0820	rRNA (adenine-C2-)-methyltransferase activity
NP71_RS07960	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NP71_RS07960	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
NP71_RS07965	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
NP71_RS07980	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NP71_RS07985	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
NP71_RS07990	COG1758	RNA polymerase activity
NP71_RS08020	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
NP71_RS08025	COG0284	orotidine-5'-phosphate decarboxylase activity
NP71_RS08030	COG0167	dihydroorotate dehydrogenase activity
NP71_RS08040	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
NP71_RS08045	COG0505	Belongs to the CarA family
NP71_RS08065	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
NP71_RS08070	COG0564	pseudouridine synthase activity
NP71_RS08080	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
NP71_RS08085	COG3599	regulation of cell shape
NP71_RS08095	COG0673	inositol 2-dehydrogenase activity
NP71_RS08105	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NP71_RS08110	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NP71_RS08115	COG1737	Transcriptional regulator
NP71_RS08120	COG0762	integral membrane protein
NP71_RS08125	COG1799	cell septum assembly
NP71_RS08130	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
NP71_RS08135	COG1496	oxidoreductase activity
NP71_RS08140	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
NP71_RS08145	COG0849	cell division
NP71_RS08155	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
NP71_RS08160	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NP71_RS08170	COG4839	cell division protein FtsL
NP71_RS08175	COG0275	rRNA processing
NP71_RS08180	COG2001	Belongs to the MraZ family
NP71_RS08185	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
NP71_RS08190	COG0454	-acetyltransferase
NP71_RS08195	COG1011	Hydrolase
NP71_RS08200	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
NP71_RS08235	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
NP71_RS08240	COG1053	succinate dehydrogenase
NP71_RS08245	COG2009	succinate dehydrogenase
NP71_RS08250	COG0322	excinuclease ABC activity
NP71_RS08255	COG3118	belongs to the thioredoxin family
NP71_RS08260	COG1193	negative regulation of DNA recombination
NP71_RS08265	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
NP71_RS08265	COG1796	DNA polymerase
NP71_RS08275	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
NP71_RS08280	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NP71_RS08290	COG0072	phenylalanine-tRNA ligase activity
NP71_RS08290	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NP71_RS08295	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
NP71_RS08300	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NP71_RS08305	COG0333	Belongs to the bacterial ribosomal protein bL32 family
NP71_RS08320	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
NP71_RS08325	COG0742	ribosomal rna small subunit methyltransferase
NP71_RS08340	COG0584	glycerophosphoryl diester phosphodiesterase
NP71_RS08345	COG3679	Belongs to the UPF0342 family
NP71_RS08360	COG0109	protoheme IX farnesyltransferase activity
NP71_RS08365	COG1612	heme a metabolic process
NP71_RS08375	COG0772	Belongs to the SEDS family
NP71_RS08380	COG4838	Belongs to the UPF0358 family
NP71_RS08385	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
NP71_RS08390	COG4896	Protein conserved in bacteria
NP71_RS08395	COG1902	pentaerythritol trinitrate reductase activity
NP71_RS08400	COG1217	gtp-binding protein TYPA
NP71_RS08410	COG0483	inositol monophosphate 1-phosphatase activity
NP71_RS08430	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
NP71_RS08435	COG1177	transmembrane transport
NP71_RS08445	COG3842	ATPase activity
NP71_RS08455	COG4476	Belongs to the UPF0223 family
NP71_RS08485	COG0242	peptide deformylase activity
NP71_RS08495	COG5503	Protein of unknown function (DUF1447)
NP71_RS08500	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NP71_RS08505	COG0569	domain protein
NP71_RS08510	COG1294	oxidase, subunit
NP71_RS08515	COG1271	oxidase subunit
NP71_RS08525	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NP71_RS08530	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
NP71_RS08540	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
NP71_RS08555	COG1122	ATPase activity
NP71_RS08565	COG0151	Belongs to the GarS family
NP71_RS08570	COG0138	bifunctional purine biosynthesis protein purh
NP71_RS08580	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
NP71_RS08585	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
NP71_RS08590	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NP71_RS08595	COG0047	phosphoribosylformylglycinamidine synthase activity
NP71_RS08600	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NP71_RS08605	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
NP71_RS08610	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
NP71_RS08615	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
NP71_RS08620	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
NP71_RS08635	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
NP71_RS08645	COG1845	cytochrome c oxidase, subunit III
NP71_RS08650	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
NP71_RS08660	COG3212	peptidase
NP71_RS08670	COG1134	teichoic acid transport
NP71_RS08690	COG0438	transferase activity, transferring glycosyl groups
NP71_RS08695	COG1215	transferase activity, transferring glycosyl groups
NP71_RS08710	COG1682	transport, permease protein
NP71_RS08715	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
NP71_RS08720	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NP71_RS08725	COG1316	TRANSCRIPTIONal
NP71_RS08750	COG3594	Acyltransferase
NP71_RS08755	COG0436	Aminotransferase
NP71_RS08760	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
NP71_RS08765	COG2267	carboxylic ester hydrolase activity
NP71_RS08770	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
NP71_RS08775	COG1169	isochorismate synthase
NP71_RS08780	COG1575	Belongs to the MenA family. Type 1 subfamily
NP71_RS08785	COG0390	transport system, permease component
NP71_RS08790	COG4619	ABC transporter
NP71_RS08840	COG4903	ComK protein
NP71_RS08855	COG4873	Protein conserved in bacteria
NP71_RS08870	COG0737	Belongs to the 5'-nucleotidase family
NP71_RS08880	COG1696	Membrane protein involved in D-alanine export
NP71_RS08890	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
NP71_RS08895	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
NP71_RS08900	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NP71_RS08905	COG0861	Integral membrane protein TerC family
NP71_RS08920	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
NP71_RS08925	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
NP71_RS08930	COG2814	Major facilitator Superfamily
NP71_RS08935	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
NP71_RS08940	COG2382	esterase
NP71_RS08945	COG1115	amino acid carrier protein
NP71_RS08950	COG0628	permease
NP71_RS08965	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
NP71_RS08980	COG0475	glutathione-regulated potassium exporter activity
NP71_RS08980	COG0569	domain protein
NP71_RS08985	COG2239	Acts as a magnesium transporter
NP71_RS08990	COG0564	pseudouridine synthase activity
NP71_RS08995	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NP71_RS09000	COG2357	RelA SpoT domain protein
NP71_RS09010	COG4116	CYTH
NP71_RS09015	COG2346	COG2346, Truncated hemoglobins
NP71_RS09025	COG1164	Oligoendopeptidase f
NP71_RS09030	COG4469	Competence protein
NP71_RS09035	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
NP71_RS09050	COG1393	Belongs to the ArsC family
NP71_RS09055	COG0180	Tryptophanyl-tRNA synthetase
NP71_RS09060	COG4166	transmembrane transport
NP71_RS09065	COG4608	Belongs to the ABC transporter superfamily
NP71_RS09070	COG0444	Belongs to the ABC transporter superfamily
NP71_RS09075	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NP71_RS09080	COG0601	transmembrane transport
NP71_RS09105	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
NP71_RS09110	COG0542	response to heat
NP71_RS09125	COG0561	phosphatase activity
NP71_RS09130	COG0446	pyridine nucleotide-disulphide oxidoreductase
NP71_RS09140	COG0179	Fumarylacetoacetate (FAA) hydrolase
NP71_RS09145	COG1074	ATP-dependent DNA helicase activity
NP71_RS09150	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
NP71_RS09170	COG0137	argininosuccinate synthase activity
NP71_RS09180	COG0584	glycerophosphoryl diester phosphodiesterase
NP71_RS09195	COG1012	belongs to the aldehyde dehydrogenase family
NP71_RS09200	COG1098	S1 RNA binding domain
NP71_RS09205	COG1278	Cold shock
NP71_RS09225	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NP71_RS09235	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
NP71_RS09235	COG2111	Na H antiporter
NP71_RS09240	COG2111	Na H antiporter
NP71_RS09245	COG1006	Multisubunit Na H antiporter MnhC subunit
NP71_RS09250	COG0651	ATP synthesis coupled electron transport
NP71_RS09255	COG1863	multisubunit Na H antiporter MnhE subunit
NP71_RS09260	COG2212	antiporter activity
NP71_RS09265	COG1320	monovalent cation:proton antiporter activity
NP71_RS09275	COG2056	Na+-H+ antiporter family
NP71_RS09280	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
NP71_RS09285	COG1252	NADH dehydrogenase
NP71_RS09295	COG0316	Belongs to the HesB IscA family
NP71_RS09300	COG4844	belongs to the
NP71_RS09305	COG1252	NADH dehydrogenase
NP71_RS09310	COG4837	Protein of unknown function (DUF1462)
NP71_RS09315	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
NP71_RS09320	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NP71_RS09325	COG0647	UMP catabolic process
NP71_RS09330	COG2445	Protein of unknown function DUF86
NP71_RS09340	COG4470	Protein conserved in bacteria
NP71_RS09345	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
NP71_RS09350	COG0737	Belongs to the 5'-nucleotidase family
NP71_RS09355	COG0730	response to heat
NP71_RS09360	COG1801	Protein of unknown function DUF72
NP71_RS09370	COG2070	2-Nitropropane dioxygenase
NP71_RS09375	COG4536	flavin adenine dinucleotide binding
NP71_RS09400	COG5632	N-Acetylmuramoyl-L-alanine amidase
NP71_RS09400	COG1388	LysM domain
NP71_RS09495	COG0052	Belongs to the universal ribosomal protein uS2 family
NP71_RS09520	COG1783	phage Terminase large subunit
NP71_RS09595	COG1484	DNA-dependent DNA replication
NP71_RS09680	COG0719	Fe-S assembly protein
NP71_RS09685	COG0822	iron-sulfur transferase activity
NP71_RS09695	COG0719	Fe-S assembly protein
NP71_RS09700	COG0396	ATPase activity
NP71_RS09710	COG1464	Belongs to the NlpA lipoprotein family
NP71_RS09715	COG1464	Belongs to the NlpA lipoprotein family
NP71_RS09720	COG2011	ABC-type metal ion transport system permease component
NP71_RS09725	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NP71_RS09735	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NP71_RS09740	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
NP71_RS09745	COG0509	glycine decarboxylation via glycine cleavage system
NP71_RS09750	COG1393	Belongs to the ArsC family
NP71_RS09755	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NP71_RS09765	COG0710	3-dehydroquinate dehydratase activity
NP71_RS09775	COG1764	response to oxidative stress
NP71_RS09785	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
NP71_RS09795	COG2814	Major facilitator Superfamily
NP71_RS09815	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
NP71_RS09820	COG0557	exoribonuclease II activity
NP71_RS09825	COG1647	Serine aminopeptidase, S33
NP71_RS09830	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
NP71_RS09845	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
NP71_RS09850	COG0149	triose-phosphate isomerase activity
NP71_RS09855	COG0126	phosphoglycerate kinase activity
NP71_RS09860	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
NP71_RS09880	COG1090	epimerase
NP71_RS09890	COG0740	serine-type endopeptidase activity
NP71_RS09900	COG1481	regulation of sporulation
NP71_RS09905	COG0391	Required for morphogenesis under gluconeogenic growth conditions
NP71_RS09910	COG1660	Displays ATPase and GTPase activities
NP71_RS09915	COG0492	ferredoxin-NADP+ reductase activity
NP71_RS09925	COG0110	maltose O-acetyltransferase activity
NP71_RS09935	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
NP71_RS09960	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
NP71_RS09965	COG0653	protein targeting
NP71_RS09980	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
NP71_RS09990	COG1739	Uncharacterized protein family UPF0029
NP71_RS09995	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NP71_RS10015	COG2195	Cleaves the N-terminal amino acid of tripeptides
NP71_RS10020	COG1929	Belongs to the glycerate kinase type-1 family
NP71_RS10040	COG0812	UDP-N-acetylmuramate dehydrogenase activity
NP71_RS10050	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NP71_RS10055	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NP71_RS10070	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
NP71_RS10075	COG3104	oligopeptide transport
NP71_RS10080	COG3104	oligopeptide transport
NP71_RS10095	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
NP71_RS10100	COG1174	glycine betaine transport
NP71_RS10105	COG1125	glycine betaine transport
NP71_RS10105	COG0517	IMP dehydrogenase activity
NP71_RS10110	COG0514	ATP-dependent DNA helicase (RecQ)
NP71_RS10115	COG0488	(ABC) transporter
NP71_RS10125	COG1368	sulfuric ester hydrolase activity
NP71_RS10135	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
NP71_RS10155	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
NP71_RS10155	COG0512	Glutamine amidotransferase of anthranilate synthase
NP71_RS10165	COG0720	synthase
NP71_RS10180	COG2261	transglycosylase associated protein
NP71_RS10190	COG0463	Glycosyl transferase, family 2
NP71_RS10195	COG1253	flavin adenine dinucleotide binding
NP71_RS10200	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
NP71_RS10200	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
NP71_RS10200	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
NP71_RS10205	COG1105	Belongs to the carbohydrate kinase PfkB family
NP71_RS10210	COG1349	DNA-binding transcription factor activity
NP71_RS10215	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
NP71_RS10220	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
NP71_RS10245	COG0039	L-malate dehydrogenase activity
NP71_RS10255	COG4989	oxidoreductase activity
NP71_RS10270	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
NP71_RS10275	COG4988	ABC transporter
NP71_RS10280	COG1968	undecaprenyl-diphosphatase activity
NP71_RS10290	COG1671	Belongs to the UPF0178 family
NP71_RS10295	COG1611	Belongs to the LOG family
NP71_RS10325	COG2814	Major facilitator Superfamily
NP71_RS10330	COG0583	DNA-binding transcription factor activity
NP71_RS10345	COG0217	transcriptional regulatory protein
NP71_RS10355	COG2022	thiamine diphosphate biosynthetic process
NP71_RS10365	COG0352	thiamine-phosphate diphosphorylase activity
NP71_RS10380	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
NP71_RS10390	COG2205	protein histidine kinase activity
NP71_RS10395	COG0745	RESPONSE REGULATOR receiver
NP71_RS10405	COG2130	NADP-dependent
NP71_RS10410	COG0702	epimerase
NP71_RS10430	COG3942	CHAP domain
NP71_RS10430	COG1388	LysM domain
NP71_RS10435	COG0306	phosphate transporter
NP71_RS10440	COG1392	Phosphate transport regulator
NP71_RS10445	COG0577	efflux transmembrane transporter activity
NP71_RS10450	COG1136	(ABC) transporter
NP71_RS10460	COG0745	RESPONSE REGULATOR receiver
NP71_RS10465	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NP71_RS10475	COG0657	acetylesterase activity
NP71_RS10480	COG3949	Membrane
NP71_RS10490	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NP71_RS10495	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NP71_RS10500	COG1120	ATPase activity
NP71_RS10505	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
NP71_RS10510	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
NP71_RS10530	COG1132	(ABC) transporter
NP71_RS10535	COG1686	Belongs to the peptidase S11 family
NP71_RS10540	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
NP71_RS10545	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
NP71_RS10550	COG1682	transport, permease protein
NP71_RS10555	COG1134	teichoic acid transport
NP71_RS10560	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
NP71_RS10575	COG1121	(ABC) transporter
NP71_RS10580	COG1108	ABC-type Mn2 Zn2 transport systems permease components
NP71_RS10585	COG0803	Belongs to the bacterial solute-binding protein 9 family
NP71_RS10590	COG1320	monovalent cation:proton antiporter activity
NP71_RS10595	COG2212	antiporter activity
NP71_RS10600	COG1863	multisubunit Na H antiporter MnhE subunit
NP71_RS10610	COG1006	Multisubunit Na H antiporter MnhC subunit
NP71_RS10615	COG2111	Na H antiporter
NP71_RS10620	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
NP71_RS10620	COG2111	Na H antiporter
NP71_RS10625	COG0582	viral genome integration into host DNA
NP71_RS10670	COG0596	Alpha beta hydrolase
NP71_RS10680	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NP71_RS10685	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
NP71_RS10690	COG0018	arginyl-trna synthetase
NP71_RS10705	COG1078	dGTPase activity
NP71_RS10715	COG0655	NAD(P)H dehydrogenase (quinone) activity
NP71_RS10720	COG4844	belongs to the
NP71_RS10725	COG0095	Lipoate-protein ligase
NP71_RS10755	COG0471	metal ion transport
NP71_RS10760	COG2814	Major facilitator Superfamily
NP71_RS10765	COG1566	PFAM secretion protein HlyD family protein
NP71_RS10775	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NP71_RS10785	COG2363	Small membrane protein
NP71_RS10815	COG0183	Belongs to the thiolase family
NP71_RS10820	COG0318	PFAM AMP-dependent synthetase and ligase
NP71_RS10825	COG0588	phosphoglycerate mutase activity
NP71_RS10830	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
NP71_RS10840	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
NP71_RS10845	COG0363	glucosamine-6-phosphate deaminase activity
NP71_RS10875	COG0561	phosphatase activity
NP71_RS10885	COG1428	Deoxynucleoside kinase
NP71_RS10890	COG1428	Deoxynucleoside kinase
NP71_RS10905	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NP71_RS10915	COG1473	amidohydrolase
NP71_RS10920	COG0028	Belongs to the TPP enzyme family
NP71_RS10925	COG3527	Alpha-acetolactate decarboxylase
NP71_RS10935	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
NP71_RS10940	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
NP71_RS10945	COG0049	tRNA binding
NP71_RS10950	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
NP71_RS10960	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NP71_RS10965	COG0085	RNA polymerase activity
NP71_RS10970	COG2813	Specifically methylates the guanine in position
NP71_RS10980	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
NP71_RS10985	COG0081	regulation of translation
NP71_RS10990	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
NP71_RS10995	COG0250	Participates in transcription elongation, termination and antitermination
NP71_RS11000	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
NP71_RS11020	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
NP71_RS11025	COG0215	cysteine-tRNA ligase activity
NP71_RS11035	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NP71_RS11040	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
NP71_RS11050	COG4956	integral membrane protein (PIN domain superfamily)
NP71_RS11055	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
NP71_RS11065	COG3869	Catalyzes the specific phosphorylation of arginine residues in
NP71_RS11070	COG3880	PFAM UvrB UvrC protein
NP71_RS11075	COG4463	regulation of RNA biosynthetic process
NP71_RS11080	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
NP71_RS11085	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
NP71_RS11090	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
NP71_RS11095	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NP71_RS11100	COG1289	transmembrane transporter activity
NP71_RS11175	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
NP71_RS11185	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
NP71_RS11195	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
NP71_RS11200	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NP71_RS11215	COG1098	S1 RNA binding domain
NP71_RS11225	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
NP71_RS11230	COG3956	TIGRFAM MazG family protein
NP71_RS11235	COG2244	polysaccharide biosynthetic process
NP71_RS11240	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
NP71_RS11245	COG0193	aminoacyl-tRNA hydrolase activity
NP71_RS11275	COG1073	alpha beta
NP71_RS11285	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NP71_RS11290	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
NP71_RS11295	COG2088	sporulation resulting in formation of a cellular spore
NP71_RS11300	COG0251	oxidation-reduction process
NP71_RS11305	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NP71_RS11310	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
NP71_RS11315	COG4466	Protein conserved in bacteria
NP71_RS11325	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
NP71_RS11330	COG0084	hydrolase, TatD family'
NP71_RS11340	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
NP71_RS11345	COG2827	Endonuclease containing a URI domain
NP71_RS11350	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
NP71_RS11360	COG1774	PSP1 C-terminal conserved region
NP71_RS11370	COG3870	Protein conserved in bacteria
NP71_RS11375	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
NP71_RS11380	COG1982	Orn Lys Arg decarboxylase major
NP71_RS11410	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
NP71_RS11415	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
NP71_RS11420	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NP71_RS11435	COG0493	'glutamate synthase
NP71_RS11440	COG0070	glutamate synthase
NP71_RS11440	COG0069	glutamate synthase activity
NP71_RS11440	COG0067	glutamate synthase
NP71_RS11445	COG0583	DNA-binding transcription factor activity
NP71_RS11460	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
NP71_RS11475	COG1309	transcriptional regulator
NP71_RS11490	COG0626	cystathionine gamma-synthase activity
NP71_RS11495	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
NP71_RS11505	COG2272	Belongs to the type-B carboxylesterase lipase family
NP71_RS11510	COG0733	neurotransmitter:sodium symporter activity
NP71_RS11520	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
NP71_RS11525	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NP71_RS11525	COG0574	Belongs to the PEP-utilizing enzyme family
NP71_RS11535	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
NP71_RS11550	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NP71_RS11570	COG1124	(ABC) transporter
NP71_RS11575	COG0444	Belongs to the ABC transporter superfamily
NP71_RS11580	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NP71_RS11585	COG0601	transmembrane transport
NP71_RS11620	COG2314	TM2 domain
NP71_RS11625	COG3189	MarR family transcriptional regulator
NP71_RS11630	COG2814	Major facilitator Superfamily
NP71_RS11655	COG1683	Conserved Protein
NP71_RS11660	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
NP71_RS11670	COG1136	(ABC) transporter
NP71_RS11670	COG0577	efflux transmembrane transporter activity
NP71_RS11720	COG0518	GMP synthase (glutamine-hydrolyzing) activity
NP71_RS11720	COG0519	Catalyzes the synthesis of GMP from XMP
NP71_RS11725	COG0516	GMP reductase activity
NP71_RS11725	COG0517	IMP dehydrogenase activity
NP71_RS11730	COG2233	PERMEase
NP71_RS11735	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NP71_RS11750	COG5183	chlorophyll binding
NP71_RS11760	COG1823	symporter activity
NP71_RS11765	COG0778	Nitroreductase
NP71_RS11770	COG0450	alkyl hydroperoxide reductase
NP71_RS11780	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
NP71_RS11785	COG5646	InterPro IPR014922
NP71_RS11790	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NP71_RS11795	COG2011	ABC-type metal ion transport system permease component
NP71_RS11800	COG1464	Belongs to the NlpA lipoprotein family
NP71_RS11805	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
NP71_RS11810	COG2814	Major facilitator Superfamily
NP71_RS11820	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
NP71_RS11830	COG0360	Binds together with S18 to 16S ribosomal RNA
NP71_RS11850	COG0012	GTP binding
NP71_RS11855	COG4481	Protein conserved in bacteria
NP71_RS11860	COG0668	transmembrane transport
NP71_RS11865	COG1475	DNA binding
NP71_RS11870	COG0626	cystathionine gamma-synthase activity
NP71_RS11875	COG0626	cystathionine gamma-synthase activity
NP71_RS11880	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
NP71_RS11880	COG0646	methionine synthase
NP71_RS11895	COG0829	nickel cation binding
NP71_RS11905	COG0830	nickel cation binding
NP71_RS11910	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
NP71_RS11915	COG2353	YceI-like domain
NP71_RS11920	COG1846	Transcriptional regulator
NP71_RS11925	COG0346	lactoylglutathione lyase activity
NP71_RS11930	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
NP71_RS11935	COG0400	carboxylic ester hydrolase activity
NP71_RS11965	COG1475	DNA binding
NP71_RS11970	COG0357	Ribosomal RNA small subunit methyltransferase G
NP71_RS11975	COG0445	tRNA wobble uridine modification
NP71_RS11980	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
NP71_RS11985	COG0594	ribonuclease P activity