locus-tag	class	description
MUA46_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
MUA46_RS00010	COG0592	DNA-directed DNA polymerase activity
MUA46_RS00020	COG2501	S4 domain
MUA46_RS00030	COG0187	DNA topoisomerase II activity
MUA46_RS00040	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
MUA46_RS00045	COG2986	histidine ammonia-lyase
MUA46_RS00055	COG2353	YceI-like domain
MUA46_RS00060	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
MUA46_RS00070	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
MUA46_RS00075	COG4241	membrane
MUA46_RS00080	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
MUA46_RS00085	COG0359	binds to the 23S rRNA
MUA46_RS00090	COG0305	Participates in initiation and elongation during chromosome replication
MUA46_RS00095	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
MUA46_RS00110	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
MUA46_RS00130	COG0745	RESPONSE REGULATOR receiver
MUA46_RS00135	COG5002	protein histidine kinase activity
MUA46_RS00150	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
MUA46_RS00155	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
MUA46_RS00165	COG1388	LysM domain
MUA46_RS00185	COG1131	(ABC) transporter
MUA46_RS00225	COG1136	(ABC) transporter
MUA46_RS00230	COG1609	Transcriptional regulator
MUA46_RS00235	COG1621	beta-fructofuranosidase activity
MUA46_RS00250	COG1250	3-hydroxyacyl-CoA dehydrogenase
MUA46_RS00265	COG0415	Belongs to the DNA photolyase family
MUA46_RS00280	COG2376	Dihydroxyacetone kinase
MUA46_RS00285	COG1461	Dihydroxyacetone kinase
MUA46_RS00290	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
MUA46_RS00300	COG0577	efflux transmembrane transporter activity
MUA46_RS00300	COG0577	efflux transmembrane transporter activity
MUA46_RS00305	COG1136	(ABC) transporter
MUA46_RS00310	COG2205	protein histidine kinase activity
MUA46_RS00315	COG0745	RESPONSE REGULATOR receiver
MUA46_RS00335	COG0753	catalase activity
MUA46_RS00340	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MUA46_RS00345	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MUA46_RS00350	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
MUA46_RS00360	COG2423	ornithine cyclodeaminase activity
MUA46_RS00365	COG4264	IucA IucC family
MUA46_RS00370	COG2814	Major facilitator Superfamily
MUA46_RS00375	COG4264	IucA IucC family
MUA46_RS00380	COG4264	IucA IucC family
MUA46_RS00390	COG0019	diaminopimelate decarboxylase activity
MUA46_RS00395	COG1475	DNA binding
MUA46_RS00400	COG0706	membrane insertase activity
MUA46_RS00410	COG1869	D-ribose catabolic process
MUA46_RS00415	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
MUA46_RS00420	COG0549	Belongs to the carbamate kinase family
MUA46_RS00425	COG1288	antiporter activity
MUA46_RS00440	COG0583	DNA-binding transcription factor activity
MUA46_RS00445	COG1288	antiporter activity
MUA46_RS00450	COG1473	amidohydrolase
MUA46_RS00470	COG1288	antiporter activity
MUA46_RS00505	COG2197	response regulator
MUA46_RS00510	COG4585	Histidine kinase
MUA46_RS00515	COG0842	Transport permease protein
MUA46_RS00520	COG1131	(ABC) transporter
MUA46_RS00530	COG1737	Transcriptional regulator
MUA46_RS00535	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MUA46_RS00535	COG1263	PTS System
MUA46_RS00540	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
MUA46_RS00570	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
MUA46_RS00600	COG1695	Transcriptional regulator
MUA46_RS00610	COG3477	response to acidic pH
MUA46_RS00635	COG3711	transcriptional antiterminator
MUA46_RS00650	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
MUA46_RS00670	COG2235	arginine
MUA46_RS00685	COG4716	Myosin-crossreactive antigen
MUA46_RS00690	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
MUA46_RS00735	COG2188	Transcriptional regulator
MUA46_RS00765	COG2388	GCN5-related N-acetyl-transferase
MUA46_RS00770	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
MUA46_RS00790	COG2723	6-phospho-beta-galactosidase activity
MUA46_RS00795	COG2188	Transcriptional regulator
MUA46_RS00800	COG0492	ferredoxin-NADP+ reductase activity
MUA46_RS00805	COG1846	Transcriptional regulator
MUA46_RS00820	COG0346	lactoylglutathione lyase activity
MUA46_RS00825	COG1012	belongs to the aldehyde dehydrogenase family
MUA46_RS00825	COG1454	alcohol dehydrogenase
MUA46_RS00830	COG0471	metal ion transport
MUA46_RS00835	COG1827	regulation of RNA biosynthetic process
MUA46_RS00845	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
MUA46_RS00850	COG0157	Belongs to the NadC ModD family
MUA46_RS00855	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
MUA46_RS00870	COG0366	Alpha amylase catalytic
MUA46_RS00875	COG2188	Transcriptional regulator
MUA46_RS00880	COG2222	sugar isomerase
MUA46_RS00885	COG1105	Belongs to the carbohydrate kinase PfkB family
MUA46_RS00890	COG3684	Belongs to the aldolase LacD family
MUA46_RS00900	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
MUA46_RS00900	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MUA46_RS00905	COG3715	PTS system
MUA46_RS00910	COG3716	PTS system mannose fructose sorbose family IID component
MUA46_RS00920	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
MUA46_RS00950	COG3314	Sporulation integral membrane protein YlbJ
MUA46_RS00955	COG1414	Transcriptional regulator
MUA46_RS00960	COG0531	amino acid
MUA46_RS00975	COG1476	TRANSCRIPTIONal
MUA46_RS00985	COG1063	alcohol dehydrogenase
MUA46_RS00990	COG1620	l-lactate permease
MUA46_RS00995	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
MUA46_RS01000	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
MUA46_RS01020	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
MUA46_RS01025	COG2910	NAD(P)H-binding
MUA46_RS01030	COG2814	Major facilitator Superfamily
MUA46_RS01035	COG1309	transcriptional regulator
MUA46_RS01040	COG1063	alcohol dehydrogenase
MUA46_RS01055	COG2318	DinB family
MUA46_RS01060	COG0753	catalase activity
MUA46_RS01070	COG0783	Belongs to the Dps family
MUA46_RS01080	COG0436	Aminotransferase
MUA46_RS01110	COG2814	Major facilitator Superfamily
MUA46_RS01115	COG2162	N-hydroxyarylamine O-acetyltransferase activity
MUA46_RS01125	COG1335	isochorismatase
MUA46_RS01150	COG0431	NADPH-dependent FMN reductase
MUA46_RS01160	COG4932	domain protein
MUA46_RS01165	COG0456	acetyltransferase
MUA46_RS01170	COG1755	Isoprenylcysteine carboxyl methyltransferase
MUA46_RS01185	COG0579	oxidoreductase
MUA46_RS01215	COG1073	alpha beta
MUA46_RS01235	COG0438	transferase activity, transferring glycosyl groups
MUA46_RS01240	COG0183	Belongs to the thiolase family
MUA46_RS01245	COG1024	Enoyl-CoA hydratase
MUA46_RS01245	COG1250	3-hydroxyacyl-CoA dehydrogenase
MUA46_RS01250	COG1960	acyl-CoA dehydrogenase activity
MUA46_RS01255	COG0318	PFAM AMP-dependent synthetase and ligase
MUA46_RS01265	COG1960	acyl-CoA dehydrogenase activity
MUA46_RS01270	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MUA46_RS01290	COG0563	adenylate kinase activity
MUA46_RS01300	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MUA46_RS01330	COG1328	CTP reductase activity
MUA46_RS01335	COG0602	queuosine metabolic process
MUA46_RS01360	COG1942	4-Oxalocrotonate Tautomerase
MUA46_RS01375	COG0803	Belongs to the bacterial solute-binding protein 9 family
MUA46_RS01375	COG3443	Belongs to the bacterial solute-binding protein 9 family
MUA46_RS01405	COG4753	response regulator
MUA46_RS01405	COG2207	Transcriptional regulator
MUA46_RS01425	COG1210	Utp--glucose-1-phosphate uridylyltransferase
MUA46_RS01430	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
MUA46_RS01435	COG2211	Major facilitator Superfamily
MUA46_RS01440	COG1957	nucleoside hydrolase
MUA46_RS01455	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
MUA46_RS01465	COG2807	transmembrane transport
MUA46_RS01470	COG1476	TRANSCRIPTIONal
MUA46_RS01475	COG0586	Pfam SNARE associated Golgi protein
MUA46_RS01490	COG1510	regulation of RNA biosynthetic process
MUA46_RS01495	COG1012	belongs to the aldehyde dehydrogenase family
MUA46_RS01500	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
MUA46_RS01505	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
MUA46_RS01505	COG0140	phosphoribosyl-ATP diphosphatase activity
MUA46_RS01520	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
MUA46_RS01525	COG0131	Imidazoleglycerol-phosphate dehydratase
MUA46_RS01530	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
MUA46_RS01535	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
MUA46_RS01540	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
MUA46_RS01545	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
MUA46_RS01580	COG2376	Dihydroxyacetone kinase
MUA46_RS01585	COG1461	Dihydroxyacetone kinase
MUA46_RS01595	COG2824	Alkylphosphonate utilization operon protein PhnA
MUA46_RS01600	COG1012	belongs to the aldehyde dehydrogenase family
MUA46_RS01610	COG0596	Alpha beta hydrolase
MUA46_RS01620	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
MUA46_RS01620	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
MUA46_RS01620	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
MUA46_RS01630	COG1705	Flagellar rod assembly protein muramidase FlgJ
MUA46_RS01630	COG3942	CHAP domain
MUA46_RS01640	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
MUA46_RS01655	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
MUA46_RS01660	COG0747	negative chemotaxis
MUA46_RS01685	COG0463	Glycosyl transferase, family 2
MUA46_RS01685	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
MUA46_RS01705	COG3181	Tripartite tricarboxylate transporter family receptor
MUA46_RS01710	COG0778	Nitroreductase
MUA46_RS01715	COG3001	Fructosamine kinase
MUA46_RS01735	COG1136	(ABC) transporter
MUA46_RS01740	COG1136	(ABC) transporter
MUA46_RS01740	COG0577	efflux transmembrane transporter activity
MUA46_RS01760	COG4413	Urea transporter
MUA46_RS01765	COG0831	urea catabolic process
MUA46_RS01770	COG0832	Belongs to the urease beta subunit family
MUA46_RS01775	COG0804	urea catabolic process
MUA46_RS01780	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
MUA46_RS01785	COG1063	alcohol dehydrogenase
MUA46_RS01790	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
MUA46_RS01795	COG0717	Belongs to the dCTP deaminase family
MUA46_RS01800	COG0523	cobalamin synthesis protein
MUA46_RS01825	COG1181	Belongs to the D-alanine--D-alanine ligase family
MUA46_RS01835	COG0583	DNA-binding transcription factor activity
MUA46_RS01845	COG1346	cytolysis
MUA46_RS01855	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MUA46_RS01860	COG4605	iron ion homeostasis
MUA46_RS01865	COG4604	ABC transporter, ATP-binding protein
MUA46_RS01870	COG4607	ABC-type enterochelin transport system periplasmic component
MUA46_RS01885	COG0778	Nitroreductase
MUA46_RS01890	COG2357	RelA SpoT domain protein
MUA46_RS01900	COG3942	CHAP domain
MUA46_RS01920	COG0596	Alpha beta hydrolase
MUA46_RS01945	COG1028	Short-chain dehydrogenase reductase Sdr
MUA46_RS01965	COG3835	regulator
MUA46_RS01980	COG3961	Belongs to the TPP enzyme family
MUA46_RS01985	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
MUA46_RS01990	COG0512	Glutamine amidotransferase of anthranilate synthase
MUA46_RS01995	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
MUA46_RS02000	COG0134	indole-3-glycerol-phosphate synthase activity
MUA46_RS02005	COG0135	phosphoribosylanthranilate isomerase activity
MUA46_RS02010	COG0133	tryptophan synthase activity
MUA46_RS02015	COG0159	tryptophan synthase activity
MUA46_RS02030	COG1132	(ABC) transporter
MUA46_RS02035	COG1132	(ABC) transporter
MUA46_RS02045	COG1115	amino acid carrier protein
MUA46_RS02050	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
MUA46_RS02055	COG2814	Major facilitator Superfamily
MUA46_RS02060	COG2271	Major facilitator Superfamily
MUA46_RS02065	COG3764	Sortase (surface protein transpeptidase)
MUA46_RS02070	COG1929	Belongs to the glycerate kinase type-1 family
MUA46_RS02075	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
MUA46_RS02085	COG1174	glycine betaine transport
MUA46_RS02105	COG1882	Formate acetyltransferase
MUA46_RS02110	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
MUA46_RS02125	COG0702	epimerase
MUA46_RS02135	COG0444	Belongs to the ABC transporter superfamily
MUA46_RS02140	COG4608	Belongs to the ABC transporter superfamily
MUA46_RS02145	COG0601	transmembrane transport
MUA46_RS02150	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MUA46_RS02165	COG1760	l-serine dehydratase
MUA46_RS02170	COG1760	l-serine dehydratase
MUA46_RS02205	COG0471	metal ion transport
MUA46_RS02225	COG0454	-acetyltransferase
MUA46_RS02240	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
MUA46_RS02245	COG2146	nitrite reductase [NAD(P)H] activity
MUA46_RS02250	COG1648	precorrin-2 dehydrogenase activity
MUA46_RS02250	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
MUA46_RS02255	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
MUA46_RS02260	COG1140	nitrate reductase beta subunit
MUA46_RS02270	COG2181	nitrate reductase activity
MUA46_RS02280	COG4585	Histidine kinase
MUA46_RS02285	COG2197	response regulator
MUA46_RS02295	COG2223	nitrite transmembrane transporter activity
MUA46_RS02305	COG0039	L-malate dehydrogenase activity
MUA46_RS02315	COG1363	Peptidase, m42
MUA46_RS02330	COG2807	transmembrane transport
MUA46_RS02350	COG1283	sodium-dependent phosphate transmembrane transporter activity
MUA46_RS02375	COG2814	Major facilitator Superfamily
MUA46_RS02380	COG0604	alcohol dehydrogenase
MUA46_RS02390	COG1620	l-lactate permease
MUA46_RS02405	COG0438	transferase activity, transferring glycosyl groups
MUA46_RS02435	COG1434	Gram-negative-bacterium-type cell wall biogenesis
MUA46_RS02455	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
MUA46_RS02465	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MUA46_RS02490	COG1304	FMN binding
MUA46_RS02495	COG0523	cobalamin synthesis protein
MUA46_RS02510	COG0786	glutamate:sodium symporter activity
MUA46_RS02515	COG2207	Transcriptional regulator
MUA46_RS02525	COG1695	Transcriptional regulator
MUA46_RS02540	COG1757	Na H antiporter
MUA46_RS02545	COG2094	Belongs to the DNA glycosylase MPG family
MUA46_RS02555	COG1288	antiporter activity
MUA46_RS02560	COG4152	abc transporter atp-binding protein
MUA46_RS02565	COG1668	transmembrane transport
MUA46_RS02570	COG1742	UPF0060 membrane protein
MUA46_RS02575	COG2017	converts alpha-aldose to the beta-anomer
MUA46_RS02580	COG1476	TRANSCRIPTIONal
MUA46_RS02585	COG2258	MOSC domain
MUA46_RS02590	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
MUA46_RS02600	COG0010	Belongs to the arginase family
MUA46_RS02605	COG0583	DNA-binding transcription factor activity
MUA46_RS02610	COG3314	Sporulation integral membrane protein YlbJ
MUA46_RS02620	COG1228	amidohydrolase
MUA46_RS02625	COG0659	secondary active sulfate transmembrane transporter activity
MUA46_RS02630	COG1473	amidohydrolase
MUA46_RS02655	COG0385	Bile acid
MUA46_RS02685	COG1113	amino acid transport
MUA46_RS02710	COG1316	TRANSCRIPTIONal
MUA46_RS02725	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
MUA46_RS02730	COG3383	formate dehydrogenase (NAD+) activity
MUA46_RS02755	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MUA46_RS02760	COG2076	Multidrug Resistance protein
MUA46_RS02765	COG2076	Multidrug Resistance protein
MUA46_RS02780	COG1757	Na H antiporter
MUA46_RS02790	COG3942	CHAP domain
MUA46_RS02810	COG1960	acyl-CoA dehydrogenase activity
MUA46_RS02820	COG2832	Protein of unknown function (DUF454)
MUA46_RS02825	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
MUA46_RS02830	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MUA46_RS02840	COG2186	Transcriptional regulator
MUA46_RS02845	COG1940	carbohydrate kinase activity
MUA46_RS02850	COG1268	BioY protein
MUA46_RS02865	COG1609	Transcriptional regulator
MUA46_RS02870	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
MUA46_RS02875	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
MUA46_RS02880	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
MUA46_RS02885	COG0725	ABC transporter, periplasmic molybdate-binding protein
MUA46_RS02890	COG4149	molybdate abc transporter
MUA46_RS02895	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
MUA46_RS02900	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
MUA46_RS02905	COG0521	Mo-molybdopterin cofactor biosynthetic process
MUA46_RS02910	COG0315	cyclic pyranopterin monophosphate synthase activity
MUA46_RS02925	COG0314	molybdopterin synthase activity
MUA46_RS02935	COG0746	molybdenum cofactor guanylyltransferase activity
MUA46_RS02940	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
MUA46_RS02970	COG2348	transferase activity, transferring amino-acyl groups
MUA46_RS02975	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MUA46_RS02980	COG0436	Aminotransferase
MUA46_RS03015	COG2252	PERMEase
MUA46_RS03030	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
MUA46_RS03035	COG0088	Forms part of the polypeptide exit tunnel
MUA46_RS03040	COG0089	rRNA binding
MUA46_RS03045	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
MUA46_RS03050	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
MUA46_RS03055	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
MUA46_RS03060	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
MUA46_RS03070	COG0255	Belongs to the universal ribosomal protein uL29 family
MUA46_RS03080	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
MUA46_RS03085	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
MUA46_RS03090	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
MUA46_RS03095	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MUA46_RS03100	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
MUA46_RS03120	COG1841	ribosomal large subunit assembly
MUA46_RS03130	COG0201	protein transport
MUA46_RS03145	COG0257	Belongs to the bacterial ribosomal protein bL36 family
MUA46_RS03155	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
MUA46_RS03160	COG0202	RNA polymerase activity
MUA46_RS03165	COG0203	ribosomal protein L17
MUA46_RS03170	COG1122	ATPase activity
MUA46_RS03175	COG1122	ATPase activity
MUA46_RS03185	COG0101	tRNA pseudouridine synthase activity
MUA46_RS03195	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
MUA46_RS03210	COG0789	Transcriptional regulator
MUA46_RS03215	COG1335	isochorismatase
MUA46_RS03220	COG0488	(ABC) transporter
MUA46_RS03225	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MUA46_RS03235	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
MUA46_RS03250	COG1302	Protein conserved in bacteria
MUA46_RS03255	COG2814	Major facilitator Superfamily
MUA46_RS03260	COG4264	IucA IucC family
MUA46_RS03265	COG2814	Major facilitator Superfamily
MUA46_RS03270	COG4264	IucA IucC family
MUA46_RS03275	COG3457	Alanine racemase
MUA46_RS03280	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
MUA46_RS03285	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MUA46_RS03290	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MUA46_RS03295	COG3314	Sporulation integral membrane protein YlbJ
MUA46_RS03305	COG1988	membrane-bound metal-dependent
MUA46_RS03310	COG4284	Utp--glucose-1-phosphate uridylyltransferase
MUA46_RS03315	COG1272	protein, Hemolysin III
MUA46_RS03335	COG2814	Major facilitator Superfamily
MUA46_RS03340	COG0489	protein tyrosine kinase activity
MUA46_RS03410	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MUA46_RS03425	COG0561	phosphatase activity
MUA46_RS03435	COG2186	Transcriptional regulator
MUA46_RS03440	COG1482	cell wall glycoprotein biosynthetic process
MUA46_RS03465	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
MUA46_RS03495	COG5146	pantothenate kinase activity
MUA46_RS03505	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MUA46_RS03520	COG2271	Major facilitator Superfamily
MUA46_RS03530	COG0191	fructose-bisphosphate aldolase activity
MUA46_RS03535	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MUA46_RS03540	COG1733	regulation of RNA biosynthetic process
MUA46_RS03550	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
MUA46_RS03555	COG0254	rRNA binding
MUA46_RS03565	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
MUA46_RS03570	COG2890	protein-(glutamine-N5) methyltransferase activity
MUA46_RS03575	COG0009	L-threonylcarbamoyladenylate synthase
MUA46_RS03580	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MUA46_RS03585	COG4475	Protein of unknown function (DUF436)
MUA46_RS03595	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
MUA46_RS03600	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
MUA46_RS03610	COG0356	it plays a direct role in the translocation of protons across the membrane
MUA46_RS03615	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MUA46_RS03625	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MUA46_RS03630	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
MUA46_RS03635	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
MUA46_RS03655	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MUA46_RS03665	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
MUA46_RS03690	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
MUA46_RS03695	COG0352	thiamine-phosphate diphosphorylase activity
MUA46_RS03700	COG0706	membrane insertase activity
MUA46_RS03720	COG1418	mRNA catabolic process
MUA46_RS03725	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MUA46_RS03730	COG1937	Protein conserved in bacteria
MUA46_RS03745	COG2217	Heavy metal translocating P-type atpase
MUA46_RS03755	COG0772	Belongs to the SEDS family
MUA46_RS03765	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
MUA46_RS03770	COG0513	Belongs to the DEAD box helicase family
MUA46_RS03790	COG0736	holo-[acyl-carrier-protein] synthase activity
MUA46_RS03795	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MUA46_RS03805	COG2337	Toxic component of a toxin-antitoxin (TA) module
MUA46_RS03810	COG2208	phosphoserine phosphatase activity
MUA46_RS03815	COG1366	Belongs to the anti-sigma-factor antagonist family
MUA46_RS03825	COG1191	sigma factor activity
MUA46_RS03835	COG2183	response to ionizing radiation
MUA46_RS03875	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
MUA46_RS03885	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
MUA46_RS03895	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
MUA46_RS03910	COG0028	Belongs to the TPP enzyme family
MUA46_RS03915	COG0129	dihydroxy-acid dehydratase activity
MUA46_RS03920	COG0802	atpase or kinase
MUA46_RS03925	COG1214	PFAM Peptidase M22, glycoprotease
MUA46_RS03930	COG0456	acetyltransferase
MUA46_RS03935	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
MUA46_RS03940	COG0488	(ABC) transporter
MUA46_RS03945	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
MUA46_RS03950	COG2391	methyltransferase activity
MUA46_RS03955	COG0425	Belongs to the sulfur carrier protein TusA family
MUA46_RS03960	COG1621	beta-fructofuranosidase activity
MUA46_RS03980	COG4512	PFAM Accessory gene regulator B
MUA46_RS04020	COG1464	Belongs to the NlpA lipoprotein family
MUA46_RS04025	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
MUA46_RS04050	COG1131	(ABC) transporter
MUA46_RS04060	COG1802	Transcriptional regulator
MUA46_RS04065	COG1070	Carbohydrate kinase
MUA46_RS04070	COG2610	gluconate transmembrane transporter activity
MUA46_RS04110	COG2706	6-phosphogluconolactonase activity
MUA46_RS04115	COG1012	belongs to the aldehyde dehydrogenase family
MUA46_RS04125	COG1227	inorganic diphosphatase activity
MUA46_RS04130	COG1335	isochorismatase
MUA46_RS04140	COG0077	Prephenate dehydratase
MUA46_RS04150	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
MUA46_RS04160	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
MUA46_RS04170	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
MUA46_RS04175	COG4496	protein, YerC YecD
MUA46_RS04180	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
MUA46_RS04185	COG0210	DNA helicase
MUA46_RS04190	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
MUA46_RS04195	COG4851	CamS sex pheromone cAM373 precursor
MUA46_RS04200	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MUA46_RS04205	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MUA46_RS04210	COG0154	amidase activity
MUA46_RS04215	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MUA46_RS04225	COG1597	lipid kinase activity
MUA46_RS04230	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MUA46_RS04245	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MUA46_RS04255	COG1528	Iron-storage protein
MUA46_RS04270	COG0673	inositol 2-dehydrogenase activity
MUA46_RS04275	COG2211	Major facilitator Superfamily
MUA46_RS04280	COG4409	exo-alpha-(2->6)-sialidase activity
MUA46_RS04285	COG4129	membrane
MUA46_RS04290	COG0024	Methionine aminopeptidase
MUA46_RS04315	COG0288	reversible hydration of carbon dioxide
MUA46_RS04320	COG1295	ribonuclease BN
MUA46_RS04330	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MUA46_RS04335	COG4840	Belongs to the UPF0435 family
MUA46_RS04340	COG2309	aminopeptidase activity
MUA46_RS04345	COG1607	acyl-coa hydrolase
MUA46_RS04350	COG0535	radical SAM domain protein
MUA46_RS04360	COG0693	protein deglycase activity
MUA46_RS04365	COG0028	Belongs to the TPP enzyme family
MUA46_RS04370	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
MUA46_RS04375	COG2137	regulation of response to DNA damage stimulus
MUA46_RS04385	COG1134	teichoic acid transport
MUA46_RS04385	COG1388	LysM domain
MUA46_RS04395	COG1988	membrane-bound metal-dependent
MUA46_RS04420	COG4129	membrane
MUA46_RS04425	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
MUA46_RS04430	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
MUA46_RS04440	COG0735	belongs to the Fur family
MUA46_RS04595	COG1181	Belongs to the D-alanine--D-alanine ligase family
MUA46_RS04605	COG0765	amino acid transport
MUA46_RS04610	COG1126	abc transporter atp-binding protein
MUA46_RS04615	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
MUA46_RS04625	COG0363	glucosamine-6-phosphate deaminase activity
MUA46_RS04640	COG0114	fumarate hydratase activity
MUA46_RS04650	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
MUA46_RS04660	COG0564	pseudouridine synthase activity
MUA46_RS04665	COG4585	Histidine kinase
MUA46_RS04665	COG2203	Gaf domain
MUA46_RS04670	COG2197	response regulator
MUA46_RS04680	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MUA46_RS04705	COG4399	Belongs to the UPF0754 family
MUA46_RS04710	COG3679	Belongs to the UPF0342 family
MUA46_RS04715	COG0420	3'-5' exonuclease activity
MUA46_RS04725	COG3481	metal-dependent phosphohydrolase, HD sub domain
MUA46_RS04735	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
MUA46_RS04745	COG1846	Transcriptional regulator
MUA46_RS04755	COG0537	adenosine 5'-monophosphoramidase activity
MUA46_RS04760	COG1131	(ABC) transporter
MUA46_RS04765	COG4473	ABC transporter
MUA46_RS04775	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
MUA46_RS04780	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
MUA46_RS04785	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
MUA46_RS04790	COG3545	Serine hydrolase
MUA46_RS04920	COG0076	glutamate decarboxylase activity
MUA46_RS04940	COG0318	PFAM AMP-dependent synthetase and ligase
MUA46_RS04950	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
MUA46_RS04960	COG1506	peptidase
MUA46_RS04965	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
MUA46_RS04970	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
MUA46_RS04980	COG0656	L-ascorbic acid biosynthetic process
MUA46_RS04985	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MUA46_RS05000	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
MUA46_RS05025	COG3266	domain, Protein
MUA46_RS05025	COG5632	N-Acetylmuramoyl-L-alanine amidase
MUA46_RS05025	COG4193	domain, Protein
MUA46_RS05040	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
MUA46_RS05040	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
MUA46_RS05050	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
MUA46_RS05050	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
MUA46_RS05055	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
MUA46_RS05060	COG0506	proline dehydrogenase activity
MUA46_RS05070	COG2267	carboxylic ester hydrolase activity
MUA46_RS05075	COG0039	L-malate dehydrogenase activity
MUA46_RS05085	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
MUA46_RS05090	COG1242	4 iron, 4 sulfur cluster binding
MUA46_RS05095	COG2814	Major facilitator Superfamily
MUA46_RS05100	COG0495	leucyl-tRNA aminoacylation
MUA46_RS05105	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MUA46_RS05110	COG2081	HI0933 family
MUA46_RS05115	COG2244	polysaccharide biosynthetic process
MUA46_RS05120	COG1187	pseudouridine synthase activity
MUA46_RS05130	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
MUA46_RS05135	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
MUA46_RS05140	COG0510	thiamine kinase activity
MUA46_RS05145	COG0220	tRNA (guanine-N7-)-methyltransferase activity
MUA46_RS05155	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MUA46_RS05165	COG1363	Peptidase, m42
MUA46_RS05170	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MUA46_RS05180	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MUA46_RS05185	COG1674	ftsk spoiiie
MUA46_RS05190	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
MUA46_RS05205	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
MUA46_RS05205	COG1605	Chorismate mutase
MUA46_RS05210	COG1609	Transcriptional regulator
MUA46_RS05215	COG0123	including yeast histone deacetylase and acetoin utilization protein
MUA46_RS05220	COG0454	-acetyltransferase
MUA46_RS05225	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
MUA46_RS05230	COG2759	Belongs to the formate--tetrahydrofolate ligase family
MUA46_RS05235	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
MUA46_RS05245	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MUA46_RS05250	COG0204	Acyl-transferase
MUA46_RS05260	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
MUA46_RS05265	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
MUA46_RS05270	COG1764	response to oxidative stress
MUA46_RS05275	COG0584	glycerophosphoryl diester phosphodiesterase
MUA46_RS05290	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
MUA46_RS05295	COG1956	GAF domain-containing protein
MUA46_RS05300	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
MUA46_RS05305	COG1104	cysteine desulfurase activity
MUA46_RS05310	COG0301	tRNA thio-modification
MUA46_RS05320	COG0616	signal peptide processing
MUA46_RS05330	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
MUA46_RS05335	COG0827	DNA restriction-modification system
MUA46_RS05340	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MUA46_RS05345	COG0589	response to stress
MUA46_RS05350	COG0686	Belongs to the AlaDH PNT family
MUA46_RS05360	COG0006	proline dipeptidase activity
MUA46_RS05365	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
MUA46_RS05375	COG4109	DRTGG domain
MUA46_RS05380	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
MUA46_RS05385	COG0587	DNA-directed DNA polymerase activity
MUA46_RS05390	COG0281	malic enzyme
MUA46_RS05395	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
MUA46_RS05400	COG0825	malonyl-CoA metabolic process
MUA46_RS05405	COG0205	6-phosphofructokinase activity
MUA46_RS05410	COG0469	pyruvate kinase activity
MUA46_RS05415	COG0372	Belongs to the citrate synthase family
MUA46_RS05420	COG0538	isocitrate dehydrogenase activity
MUA46_RS05425	COG0745	RESPONSE REGULATOR receiver
MUA46_RS05430	COG5002	protein histidine kinase activity
MUA46_RS05435	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MUA46_RS05435	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MUA46_RS05445	COG0237	dephospho-CoA kinase activity
MUA46_RS05450	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
MUA46_RS05455	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
MUA46_RS05460	COG3611	Membrane attachment protein
MUA46_RS05465	COG1484	DNA-dependent DNA replication
MUA46_RS05470	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
MUA46_RS05475	COG0833	amino acid
MUA46_RS05480	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
MUA46_RS05485	COG0291	Belongs to the bacterial ribosomal protein bL35 family
MUA46_RS05495	COG4112	unkown
MUA46_RS05505	COG0544	peptidyl-prolyl cis-trans isomerase activity
MUA46_RS05510	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
MUA46_RS05515	COG0218	Necessary for normal cell division and for the maintenance of normal septation
MUA46_RS05520	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
MUA46_RS05525	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
MUA46_RS05530	COG0181	hydroxymethylbilane synthase activity
MUA46_RS05540	COG0113	porphobilinogen synthase activity
MUA46_RS05545	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
MUA46_RS05555	COG2818	Glycosylase
MUA46_RS05560	COG0525	valine-tRNA ligase activity
MUA46_RS05565	COG0285	dihydrofolate synthase activity
MUA46_RS05575	COG2003	Belongs to the UPF0758 family
MUA46_RS05650	COG0261	This protein binds to 23S rRNA in the presence of protein L20
MUA46_RS05655	COG2868	ribosomal protein
MUA46_RS05670	COG4492	Belongs to the UPF0735 family
MUA46_RS05675	COG0632	four-way junction helicase activity
MUA46_RS05680	COG2255	four-way junction helicase activity
MUA46_RS05695	COG1862	Preprotein translocase
MUA46_RS05700	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
MUA46_RS05700	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
MUA46_RS05705	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
MUA46_RS05705	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
MUA46_RS05710	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
MUA46_RS05720	COG1490	D-aminoacyl-tRNA deacylase activity
MUA46_RS05725	COG0860	N-Acetylmuramoyl-L-alanine amidase
MUA46_RS05735	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
MUA46_RS05745	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
MUA46_RS05750	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
MUA46_RS05755	COG1959	2 iron, 2 sulfur cluster binding
MUA46_RS05775	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MUA46_RS05780	COG1104	cysteine desulfurase activity
MUA46_RS05785	COG0482	sulfurtransferase activity
MUA46_RS05795	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
MUA46_RS05800	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
MUA46_RS05805	COG4472	Bacterial protein of unknown function (DUF965)
MUA46_RS05810	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
MUA46_RS05815	COG3906	Belongs to the UPF0473 family
MUA46_RS05820	COG4122	O-methyltransferase activity
MUA46_RS05825	COG0826	peptidase U32
MUA46_RS05830	COG0826	peptidase U32
MUA46_RS05835	COG0572	uridine kinase
MUA46_RS05845	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
MUA46_RS05850	COG1984	allophanate hydrolase subunit 2
MUA46_RS05855	COG0511	ligase activity, forming carbon-carbon bonds
MUA46_RS05860	COG0439	Biotin carboxylase
MUA46_RS05865	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
MUA46_RS05870	COG1914	H( )-stimulated, divalent metal cation uptake system
MUA46_RS05875	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
MUA46_RS05880	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
MUA46_RS05885	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
MUA46_RS05890	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
MUA46_RS05895	COG1534	Rna-binding protein
MUA46_RS05905	COG1713	HD superfamily hydrolase involved in NAD metabolism
MUA46_RS05910	COG0799	negative regulation of ribosome biogenesis
MUA46_RS05915	COG2226	methyltransferase
MUA46_RS05920	COG1596	polysaccharide export
MUA46_RS05920	COG1555	photosystem II stabilization
MUA46_RS05925	COG2131	deaminase
MUA46_RS05935	COG1466	dna polymerase III delta subunit
MUA46_RS05940	COG0268	Binds directly to 16S ribosomal RNA
MUA46_RS05945	COG0481	GTPase activity
MUA46_RS05950	COG0635	Involved in the biosynthesis of porphyrin-containing compound
MUA46_RS05955	COG1420	regulation of RNA biosynthetic process
MUA46_RS05970	COG0484	heat shock protein binding
MUA46_RS05975	COG2264	protein methyltransferase activity
MUA46_RS05980	COG1385	rRNA (uridine-N3-)-methyltransferase activity
MUA46_RS05985	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
MUA46_RS06000	COG4864	UPF0365 protein
MUA46_RS06010	COG1702	phosphate starvation-inducible protein PhoH
MUA46_RS06015	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
MUA46_RS06020	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
MUA46_RS06025	COG0295	cytidine deaminase activity
MUA46_RS06035	COG1381	Involved in DNA repair and RecF pathway recombination
MUA46_RS06045	COG0423	glycine-tRNA ligase activity
MUA46_RS06050	COG0517	IMP dehydrogenase activity
MUA46_RS06055	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
MUA46_RS06060	COG0358	DNA primase activity
MUA46_RS06065	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MUA46_RS06070	COG2384	SAM-dependent methyltransferase
MUA46_RS06080	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
MUA46_RS06085	COG0513	Belongs to the DEAD box helicase family
MUA46_RS06090	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
MUA46_RS06095	COG1121	(ABC) transporter
MUA46_RS06100	COG1108	ABC-type Mn2 Zn2 transport systems permease components
MUA46_RS06105	COG0735	belongs to the Fur family
MUA46_RS06110	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
MUA46_RS06120	COG0768	penicillin binding
MUA46_RS06125	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
MUA46_RS06130	COG0573	inorganic phosphate transmembrane transporter activity
MUA46_RS06135	COG0581	inorganic phosphate transmembrane transporter activity
MUA46_RS06140	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
MUA46_RS06145	COG0704	Plays a role in the regulation of phosphate uptake
MUA46_RS06150	COG0267	Belongs to the bacterial ribosomal protein bL33 family
MUA46_RS06155	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
MUA46_RS06160	COG0705	Rhomboid family
MUA46_RS06160	COG0457	Tetratricopeptide repeat
MUA46_RS06165	COG4483	Protein conserved in bacteria
MUA46_RS06170	COG1940	carbohydrate kinase activity
MUA46_RS06175	COG0011	TIGRFAM Protein of
MUA46_RS06180	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MUA46_RS06185	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
MUA46_RS06190	COG1459	type II secretion system
MUA46_RS06205	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
MUA46_RS06210	COG0404	The glycine cleavage system catalyzes the degradation of glycine
MUA46_RS06220	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
MUA46_RS06225	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MUA46_RS06230	COG0095	Lipoate-protein ligase
MUA46_RS06245	COG0006	proline dipeptidase activity
MUA46_RS06250	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
MUA46_RS06255	COG0511	ligase activity, forming carbon-carbon bonds
MUA46_RS06260	COG0439	Biotin carboxylase
MUA46_RS06265	COG1302	Protein conserved in bacteria
MUA46_RS06290	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
MUA46_RS06295	COG1438	arginine binding
MUA46_RS06300	COG0497	DNA recombination
MUA46_RS06305	COG0280	phosphate acetyltransferase
MUA46_RS06310	COG3426	butyrate kinase activity
MUA46_RS06315	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MUA46_RS06320	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
MUA46_RS06325	COG0022	dehydrogenase e1 component
MUA46_RS06330	COG0508	dehydrogenase complex catalyzes the overall conversion of
MUA46_RS06340	COG4129	membrane
MUA46_RS06350	COG2195	Cleaves the N-terminal amino acid of tripeptides
MUA46_RS06365	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
MUA46_RS06370	COG1234	tRNA 3'-trailer cleavage
MUA46_RS06375	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MUA46_RS06385	COG0667	Aldo Keto reductase
MUA46_RS06390	COG0494	nUDIX hydrolase
MUA46_RS06395	COG0735	belongs to the Fur family
MUA46_RS06410	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
MUA46_RS06415	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
MUA46_RS06420	COG1187	pseudouridine synthase activity
MUA46_RS06425	COG0745	RESPONSE REGULATOR receiver
MUA46_RS06430	COG5002	protein histidine kinase activity
MUA46_RS06440	COG1141	Ferredoxin
MUA46_RS06450	COG0514	ATP-dependent DNA helicase (RecQ)
MUA46_RS06460	COG0492	ferredoxin-NADP+ reductase activity
MUA46_RS06470	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
MUA46_RS06475	COG0539	negative regulation of cytoplasmic translation
MUA46_RS06485	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
MUA46_RS06500	COG2226	methyltransferase
MUA46_RS06505	COG0142	geranyltranstransferase activity
MUA46_RS06510	COG0105	UTP biosynthetic process
MUA46_RS06520	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
MUA46_RS06530	COG0457	Tetratricopeptide repeat
MUA46_RS06535	COG5582	Belongs to the UPF0302 family
MUA46_RS06540	COG4347	Protein of unknown function (DUF1405)
MUA46_RS06545	COG2738	Putative neutral zinc metallopeptidase
MUA46_RS06550	COG1694	Mazg nucleotide pyrophosphohydrolase
MUA46_RS06555	COG0438	transferase activity, transferring glycosyl groups
MUA46_RS06560	COG0617	tRNA 3'-terminal CCA addition
MUA46_RS06570	COG1199	ATP-dependent helicase activity
MUA46_RS06570	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
MUA46_RS06575	COG0017	Asparaginyl-tRNA synthetase
MUA46_RS06580	COG3935	DnaD domain protein
MUA46_RS06585	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
MUA46_RS06595	COG4499	WXG100 protein secretion system (Wss), protein YukC
MUA46_RS06595	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
MUA46_RS06600	COG3331	DNA recombination
MUA46_RS06610	COG4474	Belongs to the UPF0398 family
MUA46_RS06615	COG3599	regulation of cell shape
MUA46_RS06625	COG0116	Belongs to the methyltransferase superfamily
MUA46_RS06630	COG2962	Rard protein
MUA46_RS06635	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
MUA46_RS06640	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MUA46_RS06650	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
MUA46_RS06660	COG1413	lyase activity
MUA46_RS06695	COG2190	(PTS) system
MUA46_RS06700	COG4479	Belongs to the UPF0346 family
MUA46_RS06705	COG0793	Belongs to the peptidase S41A family
MUA46_RS06715	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
MUA46_RS06720	COG0671	phosphoesterase, PA-phosphatase related
MUA46_RS06730	COG5002	protein histidine kinase activity
MUA46_RS06735	COG0567	Dehydrogenase, E1 component
MUA46_RS06760	COG0714	Associated with various cellular activities
MUA46_RS06765	COG4548	von Willebrand factor, type A
MUA46_RS06770	COG1114	Component of the transport system for branched-chain amino acids
MUA46_RS06775	COG3853	Toxic anion resistance protein (TelA)
MUA46_RS06795	COG1278	Cold shock
MUA46_RS06815	COG1473	amidohydrolase
MUA46_RS06820	COG2171	N-acyltransferase activity
MUA46_RS06825	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
MUA46_RS06830	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MUA46_RS06835	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
MUA46_RS06840	COG0488	(ABC) transporter
MUA46_RS06845	COG2996	Protein conserved in bacteria
MUA46_RS06850	COG3711	transcriptional antiterminator
MUA46_RS06855	COG1447	Phosphotransferase system cellobiose-specific component IIA
MUA46_RS06860	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
MUA46_RS06860	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
MUA46_RS06865	COG2723	6-phospho-beta-galactosidase activity
MUA46_RS06875	COG0698	ribose 5-phosphate isomerase
MUA46_RS06880	COG0698	ribose 5-phosphate isomerase
MUA46_RS06910	COG1363	Peptidase, m42
MUA46_RS06915	COG0287	Prephenate dehydrogenase
MUA46_RS06925	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MUA46_RS06955	COG0628	permease
MUA46_RS06965	COG3711	transcriptional antiterminator
MUA46_RS06970	COG1115	amino acid carrier protein
MUA46_RS06975	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MUA46_RS06980	COG0187	DNA topoisomerase II activity
MUA46_RS06985	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
MUA46_RS06990	COG4841	protein insertion into membrane
MUA46_RS06995	COG0824	Thioesterase
MUA46_RS07000	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
MUA46_RS07005	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
MUA46_RS07010	COG1970	mechanosensitive ion channel activity
MUA46_RS07025	COG4846	Membrane protein involved in cytochrome C biogenesis
MUA46_RS07035	COG3763	UPF0154 protein
MUA46_RS07045	COG4224	UPF0291 protein
MUA46_RS07055	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
MUA46_RS07065	COG0516	GMP reductase activity
MUA46_RS07080	COG0833	amino acid
MUA46_RS07090	COG0561	phosphatase activity
MUA46_RS07095	COG0083	homoserine kinase activity
MUA46_RS07100	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
MUA46_RS07105	COG0460	homoserine dehydrogenase
MUA46_RS07110	COG0527	aspartate kinase activity
MUA46_RS07150	COG1518	maintenance of DNA repeat elements
MUA46_RS07175	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
MUA46_RS07180	COG1525	nuclease
MUA46_RS07195	COG1525	nuclease
MUA46_RS07205	COG0584	glycerophosphoryl diester phosphodiesterase
MUA46_RS07235	COG4974	Belongs to the 'phage' integrase family
MUA46_RS07245	COG0789	Transcriptional regulator
MUA46_RS07250	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
MUA46_RS07255	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
MUA46_RS07260	COG0386	Belongs to the glutathione peroxidase family
MUA46_RS07265	COG1923	regulation of RNA biosynthetic process
MUA46_RS07270	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
MUA46_RS07275	COG2267	carboxylic ester hydrolase activity
MUA46_RS07280	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
MUA46_RS07290	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
MUA46_RS07300	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
MUA46_RS07305	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
MUA46_RS07325	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
MUA46_RS07335	COG1013	pyruvate-flavodoxin oxidoreductase activity
MUA46_RS07340	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
MUA46_RS07340	COG0674	pyruvate-flavodoxin oxidoreductase activity
MUA46_RS07345	COG1692	metallophosphoesterase
MUA46_RS07370	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
MUA46_RS07375	COG1546	Belongs to the CinA family
MUA46_RS07375	COG1058	Belongs to the CinA family
MUA46_RS07395	COG0300	oxidoreductase activity
MUA46_RS07400	COG0612	Peptidase, M16
MUA46_RS07405	COG0612	Peptidase, M16
MUA46_RS07410	COG2188	Transcriptional regulator
MUA46_RS07415	COG1674	ftsk spoiiie
MUA46_RS07425	COG1185	polyribonucleotide nucleotidyltransferase activity
MUA46_RS07435	COG0196	riboflavin kinase activity
MUA46_RS07440	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
MUA46_RS07445	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
MUA46_RS07450	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
MUA46_RS07455	COG1358	cellular component organization or biogenesis
MUA46_RS07460	COG2740	Nucleic-acid-binding protein implicated in transcription termination
MUA46_RS07465	COG0195	Participates in both transcription termination and antitermination
MUA46_RS07470	COG0779	Required for maturation of 30S ribosomal subunits
MUA46_RS07480	COG0442	prolyl-tRNA aminoacylation
MUA46_RS07490	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
MUA46_RS07495	COG4589	Belongs to the CDS family
MUA46_RS07500	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
MUA46_RS07505	COG0233	cytoplasmic translational termination
MUA46_RS07510	COG0528	UMP kinase activity
MUA46_RS07515	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
MUA46_RS07520	COG0052	Belongs to the universal ribosomal protein uS2 family
MUA46_RS07525	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
MUA46_RS07530	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
MUA46_RS07535	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
MUA46_RS07540	COG4974	Belongs to the 'phage' integrase family
MUA46_RS07545	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
MUA46_RS07550	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MUA46_RS07555	COG0758	DNA mediated transformation
MUA46_RS07565	COG0045	succinate-CoA ligase (ADP-forming) activity
MUA46_RS07580	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MUA46_RS07595	COG4485	Bacterial membrane protein, YfhO
MUA46_RS07615	COG0336	Belongs to the RNA methyltransferase TrmD family
MUA46_RS07625	COG0228	four-way junction DNA binding
MUA46_RS07630	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
MUA46_RS07635	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
MUA46_RS07640	COG0552	protein localization to endoplasmic reticulum
MUA46_RS07645	COG1196	nuclear chromosome segregation
MUA46_RS07655	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
MUA46_RS07670	COG0416	fatty acid biosynthetic process
MUA46_RS07675	COG1349	DNA-binding transcription factor activity
MUA46_RS07685	COG1760	l-serine dehydratase
MUA46_RS07690	COG1760	l-serine dehydratase
MUA46_RS07695	COG1461	Dihydroxyacetone kinase
MUA46_RS07700	COG1302	Protein conserved in bacteria
MUA46_RS07705	COG0227	Belongs to the bacterial ribosomal protein bL28 family
MUA46_RS07715	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
MUA46_RS07720	COG1162	GTPase activity
MUA46_RS07735	COG0820	rRNA (adenine-C2-)-methyltransferase activity
MUA46_RS07740	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MUA46_RS07740	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
MUA46_RS07745	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
MUA46_RS07760	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MUA46_RS07765	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
MUA46_RS07770	COG1758	RNA polymerase activity
MUA46_RS07800	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
MUA46_RS07805	COG0284	orotidine-5'-phosphate decarboxylase activity
MUA46_RS07810	COG0167	dihydroorotate dehydrogenase activity
MUA46_RS07820	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
MUA46_RS07825	COG0505	Belongs to the CarA family
MUA46_RS07845	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
MUA46_RS07850	COG0564	pseudouridine synthase activity
MUA46_RS07860	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
MUA46_RS07865	COG3599	regulation of cell shape
MUA46_RS07875	COG0673	inositol 2-dehydrogenase activity
MUA46_RS07880	COG4409	exo-alpha-(2->6)-sialidase activity
MUA46_RS07890	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MUA46_RS07895	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MUA46_RS07900	COG1737	Transcriptional regulator
MUA46_RS07905	COG0762	integral membrane protein
MUA46_RS07910	COG1799	cell septum assembly
MUA46_RS07915	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
MUA46_RS07920	COG1496	oxidoreductase activity
MUA46_RS07925	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
MUA46_RS07930	COG0849	cell division
MUA46_RS07940	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
MUA46_RS07945	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MUA46_RS07950	COG0768	penicillin binding
MUA46_RS07955	COG4839	cell division protein FtsL
MUA46_RS07960	COG0275	rRNA processing
MUA46_RS07965	COG2001	Belongs to the MraZ family
MUA46_RS07970	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
MUA46_RS07975	COG0454	-acetyltransferase
MUA46_RS07980	COG1011	Hydrolase
MUA46_RS07985	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
MUA46_RS08035	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
MUA46_RS08040	COG1053	succinate dehydrogenase
MUA46_RS08045	COG2009	succinate dehydrogenase
MUA46_RS08050	COG0322	excinuclease ABC activity
MUA46_RS08055	COG3118	belongs to the thioredoxin family
MUA46_RS08060	COG1193	negative regulation of DNA recombination
MUA46_RS08065	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
MUA46_RS08065	COG1796	DNA polymerase
MUA46_RS08075	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
MUA46_RS08080	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MUA46_RS08085	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MUA46_RS08085	COG0072	phenylalanine-tRNA ligase activity
MUA46_RS08090	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
MUA46_RS08095	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MUA46_RS08100	COG0333	Belongs to the bacterial ribosomal protein bL32 family
MUA46_RS08115	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
MUA46_RS08120	COG0742	ribosomal rna small subunit methyltransferase
MUA46_RS08135	COG0584	glycerophosphoryl diester phosphodiesterase
MUA46_RS08140	COG3679	Belongs to the UPF0342 family
MUA46_RS08155	COG0109	protoheme IX farnesyltransferase activity
MUA46_RS08160	COG1612	heme a metabolic process
MUA46_RS08170	COG0772	Belongs to the SEDS family
MUA46_RS08175	COG4838	Belongs to the UPF0358 family
MUA46_RS08180	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
MUA46_RS08185	COG4896	Protein conserved in bacteria
MUA46_RS08195	COG1902	pentaerythritol trinitrate reductase activity
MUA46_RS08200	COG1217	gtp-binding protein TYPA
MUA46_RS08210	COG0483	inositol monophosphate 1-phosphatase activity
MUA46_RS08230	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
MUA46_RS08235	COG1177	transmembrane transport
MUA46_RS08240	COG1176	ABC-type spermidine putrescine transport system, permease component I
MUA46_RS08245	COG3842	ATPase activity
MUA46_RS08255	COG4476	Belongs to the UPF0223 family
MUA46_RS08285	COG0242	peptide deformylase activity
MUA46_RS08295	COG5503	Protein of unknown function (DUF1447)
MUA46_RS08300	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MUA46_RS08305	COG0569	domain protein
MUA46_RS08310	COG1294	oxidase, subunit
MUA46_RS08315	COG1271	oxidase subunit
MUA46_RS08330	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MUA46_RS08335	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
MUA46_RS08345	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
MUA46_RS08365	COG1122	ATPase activity
MUA46_RS08375	COG0151	Belongs to the GarS family
MUA46_RS08380	COG0138	bifunctional purine biosynthesis protein purh
MUA46_RS08390	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
MUA46_RS08395	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
MUA46_RS08400	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MUA46_RS08405	COG0047	phosphoribosylformylglycinamidine synthase activity
MUA46_RS08410	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MUA46_RS08415	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
MUA46_RS08420	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
MUA46_RS08425	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
MUA46_RS08430	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
MUA46_RS08435	COG0438	transferase activity, transferring glycosyl groups
MUA46_RS08450	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
MUA46_RS08460	COG1845	cytochrome c oxidase, subunit III
MUA46_RS08465	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
MUA46_RS08475	COG3212	peptidase
MUA46_RS08485	COG1134	teichoic acid transport
MUA46_RS08510	COG1215	transferase activity, transferring glycosyl groups
MUA46_RS08530	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
MUA46_RS08535	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MUA46_RS08540	COG1316	TRANSCRIPTIONal
MUA46_RS08575	COG3594	Acyltransferase
MUA46_RS08580	COG0436	Aminotransferase
MUA46_RS08585	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
MUA46_RS08590	COG2267	carboxylic ester hydrolase activity
MUA46_RS08595	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
MUA46_RS08600	COG1169	isochorismate synthase
MUA46_RS08605	COG1575	Belongs to the MenA family. Type 1 subfamily
MUA46_RS08610	COG0390	transport system, permease component
MUA46_RS08615	COG4619	ABC transporter
MUA46_RS08660	COG1388	LysM domain
MUA46_RS08660	COG0860	N-Acetylmuramoyl-L-alanine amidase
MUA46_RS08820	COG2226	methyltransferase
MUA46_RS08910	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
MUA46_RS08935	COG4903	ComK protein
MUA46_RS08950	COG4873	Protein conserved in bacteria
MUA46_RS08965	COG0737	Belongs to the 5'-nucleotidase family
MUA46_RS08975	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MUA46_RS08980	COG1696	Membrane protein involved in D-alanine export
MUA46_RS08990	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
MUA46_RS09005	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
MUA46_RS09010	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MUA46_RS09015	COG0861	Integral membrane protein TerC family
MUA46_RS09020	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
MUA46_RS09030	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
MUA46_RS09035	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
MUA46_RS09040	COG2814	Major facilitator Superfamily
MUA46_RS09050	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
MUA46_RS09055	COG2382	esterase
MUA46_RS09060	COG1115	amino acid carrier protein
MUA46_RS09065	COG0628	permease
MUA46_RS09075	COG0475	glutathione-regulated potassium exporter activity
MUA46_RS09075	COG0569	domain protein
MUA46_RS09080	COG2239	Acts as a magnesium transporter
MUA46_RS09085	COG0564	pseudouridine synthase activity
MUA46_RS09090	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MUA46_RS09095	COG2357	RelA SpoT domain protein
MUA46_RS09105	COG4116	CYTH
MUA46_RS09110	COG2346	COG2346, Truncated hemoglobins
MUA46_RS09120	COG1164	Oligoendopeptidase f
MUA46_RS09125	COG4469	Competence protein
MUA46_RS09130	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
MUA46_RS09135	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MUA46_RS09145	COG1393	Belongs to the ArsC family
MUA46_RS09150	COG0180	Tryptophanyl-tRNA synthetase
MUA46_RS09155	COG4166	transmembrane transport
MUA46_RS09160	COG4608	Belongs to the ABC transporter superfamily
MUA46_RS09165	COG0444	Belongs to the ABC transporter superfamily
MUA46_RS09170	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MUA46_RS09175	COG0601	transmembrane transport
MUA46_RS09200	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
MUA46_RS09205	COG0542	response to heat
MUA46_RS09225	COG0446	pyridine nucleotide-disulphide oxidoreductase
MUA46_RS09235	COG0179	Fumarylacetoacetate (FAA) hydrolase
MUA46_RS09240	COG1074	ATP-dependent DNA helicase activity
MUA46_RS09245	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
MUA46_RS09265	COG0137	argininosuccinate synthase activity
MUA46_RS09275	COG0584	glycerophosphoryl diester phosphodiesterase
MUA46_RS09290	COG1012	belongs to the aldehyde dehydrogenase family
MUA46_RS09295	COG1098	S1 RNA binding domain
MUA46_RS09300	COG1278	Cold shock
MUA46_RS09320	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MUA46_RS09330	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
MUA46_RS09330	COG2111	Na H antiporter
MUA46_RS09335	COG2111	Na H antiporter
MUA46_RS09340	COG1006	Multisubunit Na H antiporter MnhC subunit
MUA46_RS09345	COG0651	ATP synthesis coupled electron transport
MUA46_RS09350	COG1863	multisubunit Na H antiporter MnhE subunit
MUA46_RS09355	COG2212	antiporter activity
MUA46_RS09360	COG1320	monovalent cation:proton antiporter activity
MUA46_RS09365	COG2050	protein possibly involved in aromatic compounds catabolism
MUA46_RS09370	COG2056	Na+-H+ antiporter family
MUA46_RS09375	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
MUA46_RS09380	COG1252	NADH dehydrogenase
MUA46_RS09385	COG0316	Belongs to the HesB IscA family
MUA46_RS09390	COG4844	belongs to the
MUA46_RS09395	COG1252	NADH dehydrogenase
MUA46_RS09400	COG4837	Protein of unknown function (DUF1462)
MUA46_RS09405	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
MUA46_RS09410	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MUA46_RS09415	COG0647	UMP catabolic process
MUA46_RS09420	COG2445	Protein of unknown function DUF86
MUA46_RS09430	COG4470	Protein conserved in bacteria
MUA46_RS09435	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
MUA46_RS09440	COG0737	Belongs to the 5'-nucleotidase family
MUA46_RS09445	COG0730	response to heat
MUA46_RS09450	COG1801	Protein of unknown function DUF72
MUA46_RS09470	COG1253	flavin adenine dinucleotide binding
MUA46_RS09495	COG5632	N-Acetylmuramoyl-L-alanine amidase
MUA46_RS09495	COG1388	LysM domain
MUA46_RS09585	COG4695	Portal protein
MUA46_RS09680	COG0305	Participates in initiation and elongation during chromosome replication
MUA46_RS09765	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
MUA46_RS09770	COG2176	DNA-directed DNA polymerase activity
MUA46_RS09785	COG0719	Fe-S assembly protein
MUA46_RS09790	COG0822	iron-sulfur transferase activity
MUA46_RS09800	COG0719	Fe-S assembly protein
MUA46_RS09805	COG0396	ATPase activity
MUA46_RS09815	COG1464	Belongs to the NlpA lipoprotein family
MUA46_RS09820	COG1464	Belongs to the NlpA lipoprotein family
MUA46_RS09825	COG2011	ABC-type metal ion transport system permease component
MUA46_RS09830	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MUA46_RS09835	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MUA46_RS09840	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
MUA46_RS09845	COG0509	glycine decarboxylation via glycine cleavage system
MUA46_RS09850	COG1393	Belongs to the ArsC family
MUA46_RS09855	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MUA46_RS09865	COG0710	3-dehydroquinate dehydratase activity
MUA46_RS09875	COG1764	response to oxidative stress
MUA46_RS09885	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
MUA46_RS09895	COG2814	Major facilitator Superfamily
MUA46_RS09935	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
MUA46_RS09940	COG0557	exoribonuclease II activity
MUA46_RS09945	COG1647	Serine aminopeptidase, S33
MUA46_RS09950	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
MUA46_RS09965	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
MUA46_RS09970	COG0149	triose-phosphate isomerase activity
MUA46_RS09975	COG0126	phosphoglycerate kinase activity
MUA46_RS09980	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
MUA46_RS09995	COG1090	epimerase
MUA46_RS10005	COG0740	serine-type endopeptidase activity
MUA46_RS10010	COG1481	regulation of sporulation
MUA46_RS10015	COG0391	Required for morphogenesis under gluconeogenic growth conditions
MUA46_RS10020	COG1660	Displays ATPase and GTPase activities
MUA46_RS10025	COG0492	ferredoxin-NADP+ reductase activity
MUA46_RS10035	COG0110	maltose O-acetyltransferase activity
MUA46_RS10040	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
MUA46_RS10045	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
MUA46_RS10080	COG0653	protein targeting
MUA46_RS10095	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
MUA46_RS10105	COG1739	Uncharacterized protein family UPF0029
MUA46_RS10110	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MUA46_RS10130	COG2195	Cleaves the N-terminal amino acid of tripeptides
MUA46_RS10135	COG1929	Belongs to the glycerate kinase type-1 family
MUA46_RS10155	COG0812	UDP-N-acetylmuramate dehydrogenase activity
MUA46_RS10165	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MUA46_RS10170	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MUA46_RS10185	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
MUA46_RS10200	COG3104	oligopeptide transport
MUA46_RS10205	COG3104	oligopeptide transport
MUA46_RS10220	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
MUA46_RS10225	COG1174	glycine betaine transport
MUA46_RS10230	COG0517	IMP dehydrogenase activity
MUA46_RS10230	COG1125	glycine betaine transport
MUA46_RS10235	COG0514	ATP-dependent DNA helicase (RecQ)
MUA46_RS10240	COG0488	(ABC) transporter
MUA46_RS10305	COG1368	sulfuric ester hydrolase activity
MUA46_RS10310	COG1984	allophanate hydrolase subunit 2
MUA46_RS10315	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
MUA46_RS10330	COG0512	Glutamine amidotransferase of anthranilate synthase
MUA46_RS10330	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
MUA46_RS10340	COG0720	synthase
MUA46_RS10355	COG2261	transglycosylase associated protein
MUA46_RS10365	COG0463	Glycosyl transferase, family 2
MUA46_RS10370	COG1253	flavin adenine dinucleotide binding
MUA46_RS10375	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
MUA46_RS10375	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
MUA46_RS10375	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
MUA46_RS10380	COG1105	Belongs to the carbohydrate kinase PfkB family
MUA46_RS10385	COG1349	DNA-binding transcription factor activity
MUA46_RS10390	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
MUA46_RS10395	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
MUA46_RS10420	COG0039	L-malate dehydrogenase activity
MUA46_RS10430	COG4989	oxidoreductase activity
MUA46_RS10445	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
MUA46_RS10450	COG4988	ABC transporter
MUA46_RS10455	COG1968	undecaprenyl-diphosphatase activity
MUA46_RS10465	COG1671	Belongs to the UPF0178 family
MUA46_RS10470	COG1611	Belongs to the LOG family
MUA46_RS10500	COG2814	Major facilitator Superfamily
MUA46_RS10505	COG0583	DNA-binding transcription factor activity
MUA46_RS10520	COG0217	transcriptional regulatory protein
MUA46_RS10530	COG2022	thiamine diphosphate biosynthetic process
MUA46_RS10540	COG0352	thiamine-phosphate diphosphorylase activity
MUA46_RS10555	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
MUA46_RS10565	COG2205	protein histidine kinase activity
MUA46_RS10570	COG0745	RESPONSE REGULATOR receiver
MUA46_RS10580	COG2130	NADP-dependent
MUA46_RS10585	COG0702	epimerase
MUA46_RS10600	COG2348	transferase activity, transferring amino-acyl groups
MUA46_RS10605	COG1388	LysM domain
MUA46_RS10605	COG3942	CHAP domain
MUA46_RS10615	COG0306	phosphate transporter
MUA46_RS10620	COG1392	Phosphate transport regulator
MUA46_RS10625	COG0577	efflux transmembrane transporter activity
MUA46_RS10630	COG1136	(ABC) transporter
MUA46_RS10640	COG0745	RESPONSE REGULATOR receiver
MUA46_RS10645	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
MUA46_RS10655	COG0657	acetylesterase activity
MUA46_RS10660	COG3949	Membrane
MUA46_RS10680	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MUA46_RS10685	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MUA46_RS10690	COG1120	ATPase activity
MUA46_RS10695	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
MUA46_RS10700	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
MUA46_RS10720	COG1132	(ABC) transporter
MUA46_RS10725	COG1686	Belongs to the peptidase S11 family
MUA46_RS10730	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
MUA46_RS10735	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
MUA46_RS10740	COG1682	transport, permease protein
MUA46_RS10745	COG1134	teichoic acid transport
MUA46_RS10750	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
MUA46_RS10765	COG1121	(ABC) transporter
MUA46_RS10770	COG1108	ABC-type Mn2 Zn2 transport systems permease components
MUA46_RS10775	COG0803	Belongs to the bacterial solute-binding protein 9 family
MUA46_RS10780	COG1320	monovalent cation:proton antiporter activity
MUA46_RS10785	COG2212	antiporter activity
MUA46_RS10790	COG1863	multisubunit Na H antiporter MnhE subunit
MUA46_RS10800	COG1006	Multisubunit Na H antiporter MnhC subunit
MUA46_RS10805	COG2111	Na H antiporter
MUA46_RS10810	COG2111	Na H antiporter
MUA46_RS10810	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
MUA46_RS10860	COG0596	Alpha beta hydrolase
MUA46_RS10870	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MUA46_RS10875	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
MUA46_RS10880	COG0018	arginyl-trna synthetase
MUA46_RS10895	COG1078	dGTPase activity
MUA46_RS10905	COG0655	NAD(P)H dehydrogenase (quinone) activity
MUA46_RS10910	COG4844	belongs to the
MUA46_RS10915	COG0095	Lipoate-protein ligase
MUA46_RS10940	COG0471	metal ion transport
MUA46_RS10945	COG2814	Major facilitator Superfamily
MUA46_RS10950	COG1566	PFAM secretion protein HlyD family protein
MUA46_RS10960	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MUA46_RS10970	COG2363	Small membrane protein
MUA46_RS11000	COG0588	phosphoglycerate mutase activity
MUA46_RS11005	COG1609	Transcriptional regulator
MUA46_RS11010	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
MUA46_RS11015	COG0561	phosphatase activity
MUA46_RS11020	COG0673	inositol 2-dehydrogenase activity
MUA46_RS11025	COG0738	Major facilitator superfamily
MUA46_RS11035	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
MUA46_RS11045	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
MUA46_RS11050	COG0363	glucosamine-6-phosphate deaminase activity
MUA46_RS11080	COG0561	phosphatase activity
MUA46_RS11090	COG1428	Deoxynucleoside kinase
MUA46_RS11095	COG1428	Deoxynucleoside kinase
MUA46_RS11100	COG0546	phosphoglycolate phosphatase activity
MUA46_RS11115	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
MUA46_RS11125	COG1473	amidohydrolase
MUA46_RS11130	COG0028	Belongs to the TPP enzyme family
MUA46_RS11135	COG3527	Alpha-acetolactate decarboxylase
MUA46_RS11145	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
MUA46_RS11150	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
MUA46_RS11155	COG0049	tRNA binding
MUA46_RS11160	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
MUA46_RS11170	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MUA46_RS11175	COG0085	RNA polymerase activity
MUA46_RS11180	COG2813	Specifically methylates the guanine in position
MUA46_RS11190	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
MUA46_RS11195	COG0081	regulation of translation
MUA46_RS11200	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
MUA46_RS11205	COG0250	Participates in transcription elongation, termination and antitermination
MUA46_RS11210	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
MUA46_RS11215	COG0267	Belongs to the bacterial ribosomal protein bL33 family
MUA46_RS11235	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
MUA46_RS11240	COG0215	cysteine-tRNA ligase activity
MUA46_RS11250	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MUA46_RS11255	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
MUA46_RS11265	COG4956	integral membrane protein (PIN domain superfamily)
MUA46_RS11270	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
MUA46_RS11275	COG0542	response to heat
MUA46_RS11280	COG3869	Catalyzes the specific phosphorylation of arginine residues in
MUA46_RS11285	COG3880	PFAM UvrB UvrC protein
MUA46_RS11290	COG4463	regulation of RNA biosynthetic process
MUA46_RS11295	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
MUA46_RS11300	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
MUA46_RS11305	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
MUA46_RS11310	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MUA46_RS11315	COG1289	transmembrane transporter activity
MUA46_RS11410	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
MUA46_RS11420	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
MUA46_RS11430	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
MUA46_RS11435	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MUA46_RS11450	COG1098	S1 RNA binding domain
MUA46_RS11460	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
MUA46_RS11465	COG3956	TIGRFAM MazG family protein
MUA46_RS11470	COG2244	polysaccharide biosynthetic process
MUA46_RS11475	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
MUA46_RS11480	COG0193	aminoacyl-tRNA hydrolase activity
MUA46_RS11490	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MUA46_RS11495	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
MUA46_RS11500	COG2088	sporulation resulting in formation of a cellular spore
MUA46_RS11505	COG0251	oxidation-reduction process
MUA46_RS11510	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
MUA46_RS11515	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
MUA46_RS11520	COG4466	Protein conserved in bacteria
MUA46_RS11530	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
MUA46_RS11535	COG0084	hydrolase, TatD family'
MUA46_RS11545	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
MUA46_RS11550	COG2827	Endonuclease containing a URI domain
MUA46_RS11555	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
MUA46_RS11565	COG1774	PSP1 C-terminal conserved region
MUA46_RS11575	COG3870	Protein conserved in bacteria
MUA46_RS11580	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
MUA46_RS11585	COG1982	Orn Lys Arg decarboxylase major
MUA46_RS11610	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
MUA46_RS11615	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
MUA46_RS11620	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MUA46_RS11635	COG2188	Transcriptional regulator
MUA46_RS11640	COG0366	Alpha amylase catalytic
MUA46_RS11645	COG1263	PTS System
MUA46_RS11645	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MUA46_RS11665	COG0493	'glutamate synthase
MUA46_RS11670	COG0067	glutamate synthase
MUA46_RS11670	COG0069	glutamate synthase activity
MUA46_RS11670	COG0070	glutamate synthase
MUA46_RS11690	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
MUA46_RS11705	COG1309	transcriptional regulator
MUA46_RS11720	COG0626	cystathionine gamma-synthase activity
MUA46_RS11725	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
MUA46_RS11735	COG2272	Belongs to the type-B carboxylesterase lipase family
MUA46_RS11740	COG0733	neurotransmitter:sodium symporter activity
MUA46_RS11750	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
MUA46_RS11755	COG0574	Belongs to the PEP-utilizing enzyme family
MUA46_RS11755	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MUA46_RS11775	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
MUA46_RS11810	COG0456	acetyltransferase
MUA46_RS11825	COG1124	(ABC) transporter
MUA46_RS11830	COG0444	Belongs to the ABC transporter superfamily
MUA46_RS11835	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MUA46_RS11840	COG0601	transmembrane transport
MUA46_RS11880	COG2314	TM2 domain
MUA46_RS11885	COG3189	MarR family transcriptional regulator
MUA46_RS11890	COG2814	Major facilitator Superfamily
MUA46_RS11990	COG1132	(ABC) transporter
MUA46_RS12000	COG1129	ABC transporter
MUA46_RS12025	COG0518	GMP synthase (glutamine-hydrolyzing) activity
MUA46_RS12025	COG0519	Catalyzes the synthesis of GMP from XMP
MUA46_RS12030	COG0516	GMP reductase activity
MUA46_RS12030	COG0517	IMP dehydrogenase activity
MUA46_RS12035	COG2233	PERMEase
MUA46_RS12040	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
MUA46_RS12055	COG5183	chlorophyll binding
MUA46_RS12060	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MUA46_RS12065	COG1823	symporter activity
MUA46_RS12070	COG0778	Nitroreductase
MUA46_RS12075	COG0450	alkyl hydroperoxide reductase
MUA46_RS12085	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
MUA46_RS12090	COG5646	InterPro IPR014922
MUA46_RS12095	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MUA46_RS12100	COG2011	ABC-type metal ion transport system permease component
MUA46_RS12105	COG1464	Belongs to the NlpA lipoprotein family
MUA46_RS12110	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
MUA46_RS12120	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
MUA46_RS12130	COG0360	Binds together with S18 to 16S ribosomal RNA
MUA46_RS12155	COG0012	GTP binding
MUA46_RS12160	COG4481	Protein conserved in bacteria
MUA46_RS12165	COG0668	transmembrane transport
MUA46_RS12170	COG1475	DNA binding
MUA46_RS12175	COG0626	cystathionine gamma-synthase activity
MUA46_RS12180	COG0626	cystathionine gamma-synthase activity
MUA46_RS12185	COG0646	methionine synthase
MUA46_RS12185	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
MUA46_RS12215	COG0830	nickel cation binding
MUA46_RS12220	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
MUA46_RS12230	COG1846	Transcriptional regulator
MUA46_RS12235	COG0346	lactoylglutathione lyase activity
MUA46_RS12240	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
MUA46_RS12245	COG0400	carboxylic ester hydrolase activity
MUA46_RS12295	COG0357	Ribosomal RNA small subunit methyltransferase G
MUA46_RS12300	COG0445	tRNA wobble uridine modification
MUA46_RS12305	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
MUA46_RS12310	COG0594	ribonuclease P activity