locus-tag	class	description
ENC16_RS00010	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
ENC16_RS00020	COG0516	GMP reductase activity
ENC16_RS00035	COG0833	amino acid
ENC16_RS00045	COG0561	phosphatase activity
ENC16_RS00050	COG0083	homoserine kinase activity
ENC16_RS00055	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
ENC16_RS00060	COG0460	homoserine dehydrogenase
ENC16_RS00065	COG0527	aspartate kinase activity
ENC16_RS00095	COG1518	maintenance of DNA repeat elements
ENC16_RS00110	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
ENC16_RS00115	COG1525	nuclease
ENC16_RS00130	COG1525	nuclease
ENC16_RS00140	COG0584	glycerophosphoryl diester phosphodiesterase
ENC16_RS00230	COG0789	Transcriptional regulator
ENC16_RS00235	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
ENC16_RS00240	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
ENC16_RS00245	COG0386	Belongs to the glutathione peroxidase family
ENC16_RS00250	COG1923	regulation of RNA biosynthetic process
ENC16_RS00255	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
ENC16_RS00260	COG2267	carboxylic ester hydrolase activity
ENC16_RS00265	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
ENC16_RS00275	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
ENC16_RS00285	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
ENC16_RS00290	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
ENC16_RS00295	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
ENC16_RS00310	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ENC16_RS00320	COG1013	pyruvate-flavodoxin oxidoreductase activity
ENC16_RS00325	COG0674	pyruvate-flavodoxin oxidoreductase activity
ENC16_RS00325	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
ENC16_RS00330	COG1692	metallophosphoesterase
ENC16_RS00355	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
ENC16_RS00360	COG1058	Belongs to the CinA family
ENC16_RS00360	COG1546	Belongs to the CinA family
ENC16_RS00380	COG1028	Short-chain dehydrogenase reductase Sdr
ENC16_RS00385	COG0612	Peptidase, M16
ENC16_RS00390	COG0612	Peptidase, M16
ENC16_RS00395	COG2188	Transcriptional regulator
ENC16_RS00415	COG1185	polyribonucleotide nucleotidyltransferase activity
ENC16_RS00425	COG0196	riboflavin kinase activity
ENC16_RS00430	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
ENC16_RS00435	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
ENC16_RS00440	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ENC16_RS00450	COG1131	(ABC) transporter
ENC16_RS00455	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
ENC16_RS00495	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
ENC16_RS00500	COG1358	cellular component organization or biogenesis
ENC16_RS00505	COG2740	Nucleic-acid-binding protein implicated in transcription termination
ENC16_RS00510	COG0195	Participates in both transcription termination and antitermination
ENC16_RS00515	COG0779	Required for maturation of 30S ribosomal subunits
ENC16_RS00525	COG0442	prolyl-tRNA aminoacylation
ENC16_RS00535	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
ENC16_RS00540	COG4589	Belongs to the CDS family
ENC16_RS00550	COG0233	cytoplasmic translational termination
ENC16_RS00555	COG0528	UMP kinase activity
ENC16_RS00560	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
ENC16_RS00565	COG0052	Belongs to the universal ribosomal protein uS2 family
ENC16_RS00570	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
ENC16_RS00575	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
ENC16_RS00580	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
ENC16_RS00585	COG4974	Belongs to the 'phage' integrase family
ENC16_RS00590	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
ENC16_RS00595	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
ENC16_RS00610	COG0045	succinate-CoA ligase (ADP-forming) activity
ENC16_RS00625	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
ENC16_RS00640	COG4485	Bacterial membrane protein, YfhO
ENC16_RS00650	COG0335	large ribosomal subunit rRNA binding
ENC16_RS00655	COG0336	Belongs to the RNA methyltransferase TrmD family
ENC16_RS00665	COG0228	four-way junction DNA binding
ENC16_RS00670	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
ENC16_RS00675	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
ENC16_RS00680	COG0552	protein localization to endoplasmic reticulum
ENC16_RS00685	COG1196	nuclear chromosome segregation
ENC16_RS00695	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ENC16_RS00710	COG0416	fatty acid biosynthetic process
ENC16_RS00715	COG1349	DNA-binding transcription factor activity
ENC16_RS00725	COG1760	l-serine dehydratase
ENC16_RS00730	COG1760	l-serine dehydratase
ENC16_RS00735	COG1461	Dihydroxyacetone kinase
ENC16_RS00740	COG1302	Protein conserved in bacteria
ENC16_RS00745	COG0227	Belongs to the bacterial ribosomal protein bL28 family
ENC16_RS00755	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
ENC16_RS00760	COG1162	GTPase activity
ENC16_RS00775	COG0820	rRNA (adenine-C2-)-methyltransferase activity
ENC16_RS00780	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
ENC16_RS00780	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ENC16_RS00785	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
ENC16_RS00800	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
ENC16_RS00805	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
ENC16_RS00810	COG1758	RNA polymerase activity
ENC16_RS00840	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
ENC16_RS00845	COG0284	orotidine-5'-phosphate decarboxylase activity
ENC16_RS00850	COG0167	dihydroorotate dehydrogenase activity
ENC16_RS00860	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
ENC16_RS00865	COG0505	Belongs to the CarA family
ENC16_RS00885	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
ENC16_RS00890	COG0564	pseudouridine synthase activity
ENC16_RS00900	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
ENC16_RS00905	COG3599	regulation of cell shape
ENC16_RS00915	COG0673	inositol 2-dehydrogenase activity
ENC16_RS00930	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ENC16_RS00935	COG1737	Transcriptional regulator
ENC16_RS00940	COG0762	integral membrane protein
ENC16_RS00945	COG1799	cell septum assembly
ENC16_RS00950	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
ENC16_RS00955	COG1496	oxidoreductase activity
ENC16_RS00960	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
ENC16_RS00965	COG0849	cell division
ENC16_RS00975	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
ENC16_RS00980	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ENC16_RS00985	COG0768	penicillin binding
ENC16_RS00990	COG4839	cell division protein FtsL
ENC16_RS00995	COG0275	rRNA processing
ENC16_RS01000	COG2001	Belongs to the MraZ family
ENC16_RS01005	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
ENC16_RS01010	COG0454	-acetyltransferase
ENC16_RS01015	COG1011	Hydrolase
ENC16_RS01030	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
ENC16_RS01075	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
ENC16_RS01080	COG1053	succinate dehydrogenase
ENC16_RS01085	COG2009	succinate dehydrogenase
ENC16_RS01090	COG0322	excinuclease ABC activity
ENC16_RS01095	COG3118	belongs to the thioredoxin family
ENC16_RS01100	COG1193	negative regulation of DNA recombination
ENC16_RS01105	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
ENC16_RS01105	COG1796	DNA polymerase
ENC16_RS01115	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
ENC16_RS01120	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
ENC16_RS01130	COG0072	phenylalanine-tRNA ligase activity
ENC16_RS01130	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ENC16_RS01135	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
ENC16_RS01140	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ENC16_RS01145	COG0333	Belongs to the bacterial ribosomal protein bL32 family
ENC16_RS01165	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
ENC16_RS01170	COG0742	ribosomal rna small subunit methyltransferase
ENC16_RS01190	COG3679	Belongs to the UPF0342 family
ENC16_RS01205	COG0109	protoheme IX farnesyltransferase activity
ENC16_RS01210	COG1612	heme a metabolic process
ENC16_RS01220	COG0772	Belongs to the SEDS family
ENC16_RS01225	COG4838	Belongs to the UPF0358 family
ENC16_RS01230	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
ENC16_RS01235	COG4896	Protein conserved in bacteria
ENC16_RS01240	COG1902	pentaerythritol trinitrate reductase activity
ENC16_RS01245	COG1217	gtp-binding protein TYPA
ENC16_RS01255	COG0483	inositol monophosphate 1-phosphatase activity
ENC16_RS01275	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
ENC16_RS01280	COG1177	transmembrane transport
ENC16_RS01290	COG3842	ATPase activity
ENC16_RS01300	COG4476	Belongs to the UPF0223 family
ENC16_RS01330	COG0242	peptide deformylase activity
ENC16_RS01340	COG5503	Protein of unknown function (DUF1447)
ENC16_RS01345	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
ENC16_RS01350	COG0569	domain protein
ENC16_RS01355	COG1294	oxidase, subunit
ENC16_RS01360	COG1271	oxidase subunit
ENC16_RS01370	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ENC16_RS01375	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
ENC16_RS01385	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
ENC16_RS01400	COG1122	ATPase activity
ENC16_RS01410	COG0151	Belongs to the GarS family
ENC16_RS01415	COG0138	bifunctional purine biosynthesis protein purh
ENC16_RS01425	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
ENC16_RS01430	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
ENC16_RS01435	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ENC16_RS01440	COG0047	phosphoribosylformylglycinamidine synthase activity
ENC16_RS01445	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ENC16_RS01450	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
ENC16_RS01455	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
ENC16_RS01460	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
ENC16_RS01465	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
ENC16_RS01480	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
ENC16_RS01490	COG1845	cytochrome c oxidase, subunit III
ENC16_RS01495	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
ENC16_RS01505	COG3212	peptidase
ENC16_RS01515	COG1134	teichoic acid transport
ENC16_RS01535	COG0438	transferase activity, transferring glycosyl groups
ENC16_RS01540	COG1215	transferase activity, transferring glycosyl groups
ENC16_RS01555	COG1682	transport, permease protein
ENC16_RS01560	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
ENC16_RS01565	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ENC16_RS01570	COG1316	TRANSCRIPTIONal
ENC16_RS01595	COG3594	Acyltransferase
ENC16_RS01600	COG0436	Aminotransferase
ENC16_RS01605	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
ENC16_RS01610	COG2267	carboxylic ester hydrolase activity
ENC16_RS01615	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
ENC16_RS01620	COG1169	isochorismate synthase
ENC16_RS01625	COG1575	Belongs to the MenA family. Type 1 subfamily
ENC16_RS01630	COG0390	transport system, permease component
ENC16_RS01635	COG4619	ABC transporter
ENC16_RS01685	COG4903	ComK protein
ENC16_RS01700	COG4873	Protein conserved in bacteria
ENC16_RS01715	COG0737	Belongs to the 5'-nucleotidase family
ENC16_RS01730	COG1696	Membrane protein involved in D-alanine export
ENC16_RS01740	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
ENC16_RS01745	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
ENC16_RS01750	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ENC16_RS01755	COG0861	Integral membrane protein TerC family
ENC16_RS01770	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
ENC16_RS01775	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
ENC16_RS01780	COG2814	Major facilitator Superfamily
ENC16_RS01785	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
ENC16_RS01790	COG2382	esterase
ENC16_RS01795	COG1115	amino acid carrier protein
ENC16_RS01800	COG0628	permease
ENC16_RS01825	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
ENC16_RS01840	COG0569	domain protein
ENC16_RS01840	COG0475	glutathione-regulated potassium exporter activity
ENC16_RS01845	COG2239	Acts as a magnesium transporter
ENC16_RS01850	COG0564	pseudouridine synthase activity
ENC16_RS01855	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
ENC16_RS01860	COG2357	RelA SpoT domain protein
ENC16_RS01870	COG4116	CYTH
ENC16_RS01875	COG2346	COG2346, Truncated hemoglobins
ENC16_RS01885	COG1164	Oligoendopeptidase f
ENC16_RS01890	COG4469	Competence protein
ENC16_RS01905	COG1393	Belongs to the ArsC family
ENC16_RS01910	COG0180	Tryptophanyl-tRNA synthetase
ENC16_RS01915	COG4166	transmembrane transport
ENC16_RS01920	COG4608	Belongs to the ABC transporter superfamily
ENC16_RS01925	COG0444	Belongs to the ABC transporter superfamily
ENC16_RS01930	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ENC16_RS01935	COG0601	transmembrane transport
ENC16_RS01960	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
ENC16_RS01965	COG0542	response to heat
ENC16_RS01980	COG0561	phosphatase activity
ENC16_RS01985	COG0446	pyridine nucleotide-disulphide oxidoreductase
ENC16_RS01995	COG0179	Fumarylacetoacetate (FAA) hydrolase
ENC16_RS02000	COG1074	ATP-dependent DNA helicase activity
ENC16_RS02005	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
ENC16_RS02025	COG0137	argininosuccinate synthase activity
ENC16_RS02035	COG0584	glycerophosphoryl diester phosphodiesterase
ENC16_RS02050	COG1012	belongs to the aldehyde dehydrogenase family
ENC16_RS02055	COG1098	S1 RNA binding domain
ENC16_RS02060	COG1278	Cold shock
ENC16_RS02155	COG0456	acetyltransferase
ENC16_RS02185	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
ENC16_RS02195	COG2111	Na H antiporter
ENC16_RS02195	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
ENC16_RS02200	COG2111	Na H antiporter
ENC16_RS02205	COG1006	Multisubunit Na H antiporter MnhC subunit
ENC16_RS02210	COG0651	ATP synthesis coupled electron transport
ENC16_RS02215	COG1863	multisubunit Na H antiporter MnhE subunit
ENC16_RS02220	COG2212	antiporter activity
ENC16_RS02225	COG1320	monovalent cation:proton antiporter activity
ENC16_RS02235	COG2056	Na+-H+ antiporter family
ENC16_RS02240	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
ENC16_RS02245	COG1252	NADH dehydrogenase
ENC16_RS02255	COG0316	Belongs to the HesB IscA family
ENC16_RS02260	COG4844	belongs to the
ENC16_RS02265	COG1252	NADH dehydrogenase
ENC16_RS02270	COG4837	Protein of unknown function (DUF1462)
ENC16_RS02275	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
ENC16_RS02280	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ENC16_RS02285	COG0647	UMP catabolic process
ENC16_RS02290	COG2445	Protein of unknown function DUF86
ENC16_RS02300	COG4470	Protein conserved in bacteria
ENC16_RS02305	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
ENC16_RS02310	COG0737	Belongs to the 5'-nucleotidase family
ENC16_RS02315	COG0730	response to heat
ENC16_RS02320	COG1801	Protein of unknown function DUF72
ENC16_RS02330	COG2070	2-Nitropropane dioxygenase
ENC16_RS02335	COG4536	flavin adenine dinucleotide binding
ENC16_RS02355	COG5632	N-Acetylmuramoyl-L-alanine amidase
ENC16_RS02355	COG1388	LysM domain
ENC16_RS02455	COG0052	Belongs to the universal ribosomal protein uS2 family
ENC16_RS02480	COG1783	phage Terminase large subunit
ENC16_RS02575	COG0305	Participates in initiation and elongation during chromosome replication
ENC16_RS02665	COG0719	Fe-S assembly protein
ENC16_RS02670	COG0822	iron-sulfur transferase activity
ENC16_RS02680	COG0719	Fe-S assembly protein
ENC16_RS02685	COG0396	ATPase activity
ENC16_RS02695	COG1464	Belongs to the NlpA lipoprotein family
ENC16_RS02700	COG1464	Belongs to the NlpA lipoprotein family
ENC16_RS02705	COG2011	ABC-type metal ion transport system permease component
ENC16_RS02710	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
ENC16_RS02715	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ENC16_RS02720	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
ENC16_RS02725	COG0509	glycine decarboxylation via glycine cleavage system
ENC16_RS02730	COG1393	Belongs to the ArsC family
ENC16_RS02735	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ENC16_RS02745	COG0710	3-dehydroquinate dehydratase activity
ENC16_RS02755	COG1764	response to oxidative stress
ENC16_RS02765	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
ENC16_RS02775	COG2814	Major facilitator Superfamily
ENC16_RS02805	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
ENC16_RS02810	COG0557	exoribonuclease II activity
ENC16_RS02815	COG1647	Serine aminopeptidase, S33
ENC16_RS02820	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
ENC16_RS02835	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
ENC16_RS02840	COG0149	triose-phosphate isomerase activity
ENC16_RS02845	COG0126	phosphoglycerate kinase activity
ENC16_RS02850	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
ENC16_RS02870	COG1090	epimerase
ENC16_RS02880	COG0740	serine-type endopeptidase activity
ENC16_RS02890	COG1481	regulation of sporulation
ENC16_RS02895	COG0391	Required for morphogenesis under gluconeogenic growth conditions
ENC16_RS02900	COG1660	Displays ATPase and GTPase activities
ENC16_RS02905	COG0492	ferredoxin-NADP+ reductase activity
ENC16_RS02915	COG0110	maltose O-acetyltransferase activity
ENC16_RS02925	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
ENC16_RS02960	COG0653	protein targeting
ENC16_RS02975	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
ENC16_RS02985	COG1739	Uncharacterized protein family UPF0029
ENC16_RS02990	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ENC16_RS03010	COG2195	Cleaves the N-terminal amino acid of tripeptides
ENC16_RS03015	COG1929	Belongs to the glycerate kinase type-1 family
ENC16_RS03035	COG0812	UDP-N-acetylmuramate dehydrogenase activity
ENC16_RS03045	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ENC16_RS03050	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ENC16_RS03065	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
ENC16_RS03070	COG3104	oligopeptide transport
ENC16_RS03075	COG3104	oligopeptide transport
ENC16_RS03090	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ENC16_RS03095	COG1174	glycine betaine transport
ENC16_RS03100	COG1125	glycine betaine transport
ENC16_RS03100	COG0517	IMP dehydrogenase activity
ENC16_RS03105	COG0514	ATP-dependent DNA helicase (RecQ)
ENC16_RS03110	COG0488	(ABC) transporter
ENC16_RS03120	COG1368	sulfuric ester hydrolase activity
ENC16_RS03130	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
ENC16_RS03150	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
ENC16_RS03150	COG0512	Glutamine amidotransferase of anthranilate synthase
ENC16_RS03160	COG0720	synthase
ENC16_RS03175	COG2261	transglycosylase associated protein
ENC16_RS03180	COG0463	Glycosyl transferase, family 2
ENC16_RS03185	COG1253	flavin adenine dinucleotide binding
ENC16_RS03190	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ENC16_RS03190	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ENC16_RS03190	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ENC16_RS03195	COG1105	Belongs to the carbohydrate kinase PfkB family
ENC16_RS03200	COG1349	DNA-binding transcription factor activity
ENC16_RS03205	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
ENC16_RS03210	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
ENC16_RS03235	COG0039	L-malate dehydrogenase activity
ENC16_RS03245	COG4989	oxidoreductase activity
ENC16_RS03260	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
ENC16_RS03265	COG4988	ABC transporter
ENC16_RS03270	COG1968	undecaprenyl-diphosphatase activity
ENC16_RS03280	COG1671	Belongs to the UPF0178 family
ENC16_RS03285	COG1611	Belongs to the LOG family
ENC16_RS03315	COG2814	Major facilitator Superfamily
ENC16_RS03320	COG0583	DNA-binding transcription factor activity
ENC16_RS03335	COG0217	transcriptional regulatory protein
ENC16_RS03345	COG2022	thiamine diphosphate biosynthetic process
ENC16_RS03355	COG0352	thiamine-phosphate diphosphorylase activity
ENC16_RS03370	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
ENC16_RS03385	COG2205	protein histidine kinase activity
ENC16_RS03390	COG0745	RESPONSE REGULATOR receiver
ENC16_RS03400	COG2130	NADP-dependent
ENC16_RS03405	COG0702	epimerase
ENC16_RS03425	COG1388	LysM domain
ENC16_RS03425	COG3942	CHAP domain
ENC16_RS03430	COG0306	phosphate transporter
ENC16_RS03435	COG1392	Phosphate transport regulator
ENC16_RS03440	COG0577	efflux transmembrane transporter activity
ENC16_RS03445	COG1136	(ABC) transporter
ENC16_RS03455	COG0745	RESPONSE REGULATOR receiver
ENC16_RS03460	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ENC16_RS03470	COG0657	acetylesterase activity
ENC16_RS03475	COG3949	Membrane
ENC16_RS03485	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ENC16_RS03490	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ENC16_RS03495	COG1120	ATPase activity
ENC16_RS03500	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
ENC16_RS03505	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
ENC16_RS03525	COG1132	(ABC) transporter
ENC16_RS03530	COG1686	Belongs to the peptidase S11 family
ENC16_RS03535	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
ENC16_RS03540	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
ENC16_RS03545	COG1682	transport, permease protein
ENC16_RS03550	COG1134	teichoic acid transport
ENC16_RS03555	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
ENC16_RS03570	COG1121	(ABC) transporter
ENC16_RS03575	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ENC16_RS03580	COG0803	Belongs to the bacterial solute-binding protein 9 family
ENC16_RS03585	COG1320	monovalent cation:proton antiporter activity
ENC16_RS03590	COG2212	antiporter activity
ENC16_RS03595	COG1863	multisubunit Na H antiporter MnhE subunit
ENC16_RS03605	COG1006	Multisubunit Na H antiporter MnhC subunit
ENC16_RS03610	COG2111	Na H antiporter
ENC16_RS03615	COG2111	Na H antiporter
ENC16_RS03615	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
ENC16_RS03620	COG0582	viral genome integration into host DNA
ENC16_RS03665	COG0596	Alpha beta hydrolase
ENC16_RS03675	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ENC16_RS03680	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
ENC16_RS03685	COG0018	arginyl-trna synthetase
ENC16_RS03700	COG1078	dGTPase activity
ENC16_RS03715	COG4844	belongs to the
ENC16_RS03720	COG0095	Lipoate-protein ligase
ENC16_RS03750	COG0471	metal ion transport
ENC16_RS03755	COG2814	Major facilitator Superfamily
ENC16_RS03760	COG1566	PFAM secretion protein HlyD family protein
ENC16_RS03770	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ENC16_RS03780	COG2363	Small membrane protein
ENC16_RS03810	COG0183	Belongs to the thiolase family
ENC16_RS03815	COG0318	PFAM AMP-dependent synthetase and ligase
ENC16_RS03820	COG0588	phosphoglycerate mutase activity
ENC16_RS03825	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
ENC16_RS03835	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
ENC16_RS03840	COG0363	glucosamine-6-phosphate deaminase activity
ENC16_RS03870	COG0561	phosphatase activity
ENC16_RS03880	COG1428	Deoxynucleoside kinase
ENC16_RS03885	COG1428	Deoxynucleoside kinase
ENC16_RS03900	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ENC16_RS03910	COG1473	amidohydrolase
ENC16_RS03915	COG0028	Belongs to the TPP enzyme family
ENC16_RS03920	COG3527	Alpha-acetolactate decarboxylase
ENC16_RS03930	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
ENC16_RS03935	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
ENC16_RS03940	COG0049	tRNA binding
ENC16_RS03945	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
ENC16_RS03955	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
ENC16_RS03960	COG0085	RNA polymerase activity
ENC16_RS03965	COG2813	Specifically methylates the guanine in position
ENC16_RS03975	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
ENC16_RS03985	COG0081	regulation of translation
ENC16_RS03990	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
ENC16_RS03995	COG0250	Participates in transcription elongation, termination and antitermination
ENC16_RS04000	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
ENC16_RS04005	COG0267	Belongs to the bacterial ribosomal protein bL33 family
ENC16_RS04025	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
ENC16_RS04030	COG0215	cysteine-tRNA ligase activity
ENC16_RS04040	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ENC16_RS04045	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
ENC16_RS04055	COG4956	integral membrane protein (PIN domain superfamily)
ENC16_RS04060	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
ENC16_RS04070	COG3869	Catalyzes the specific phosphorylation of arginine residues in
ENC16_RS04075	COG3880	PFAM UvrB UvrC protein
ENC16_RS04080	COG4463	regulation of RNA biosynthetic process
ENC16_RS04085	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
ENC16_RS04090	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
ENC16_RS04095	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
ENC16_RS04100	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ENC16_RS04105	COG1289	transmembrane transporter activity
ENC16_RS04180	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
ENC16_RS04190	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
ENC16_RS04200	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
ENC16_RS04205	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ENC16_RS04220	COG1098	S1 RNA binding domain
ENC16_RS04230	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
ENC16_RS04235	COG3956	TIGRFAM MazG family protein
ENC16_RS04240	COG2244	polysaccharide biosynthetic process
ENC16_RS04245	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
ENC16_RS04250	COG0193	aminoacyl-tRNA hydrolase activity
ENC16_RS04280	COG1073	alpha beta
ENC16_RS04290	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
ENC16_RS04295	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
ENC16_RS04300	COG2088	sporulation resulting in formation of a cellular spore
ENC16_RS04305	COG0251	oxidation-reduction process
ENC16_RS04310	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
ENC16_RS04315	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
ENC16_RS04320	COG4466	Protein conserved in bacteria
ENC16_RS04330	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
ENC16_RS04335	COG0084	hydrolase, TatD family'
ENC16_RS04345	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
ENC16_RS04350	COG2827	Endonuclease containing a URI domain
ENC16_RS04355	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
ENC16_RS04365	COG1774	PSP1 C-terminal conserved region
ENC16_RS04375	COG3870	Protein conserved in bacteria
ENC16_RS04380	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
ENC16_RS04385	COG1982	Orn Lys Arg decarboxylase major
ENC16_RS04415	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
ENC16_RS04420	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
ENC16_RS04425	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
ENC16_RS04445	COG0493	'glutamate synthase
ENC16_RS04450	COG0067	glutamate synthase
ENC16_RS04450	COG0069	glutamate synthase activity
ENC16_RS04450	COG0070	glutamate synthase
ENC16_RS04455	COG0583	DNA-binding transcription factor activity
ENC16_RS04470	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
ENC16_RS04485	COG1309	transcriptional regulator
ENC16_RS04500	COG0626	cystathionine gamma-synthase activity
ENC16_RS04505	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
ENC16_RS04515	COG2272	Belongs to the type-B carboxylesterase lipase family
ENC16_RS04520	COG0733	neurotransmitter:sodium symporter activity
ENC16_RS04530	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
ENC16_RS04535	COG0574	Belongs to the PEP-utilizing enzyme family
ENC16_RS04535	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ENC16_RS04545	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
ENC16_RS04560	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
ENC16_RS04580	COG1124	(ABC) transporter
ENC16_RS04585	COG0444	Belongs to the ABC transporter superfamily
ENC16_RS04590	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ENC16_RS04595	COG0601	transmembrane transport
ENC16_RS04630	COG2314	TM2 domain
ENC16_RS04635	COG3189	MarR family transcriptional regulator
ENC16_RS04640	COG2814	Major facilitator Superfamily
ENC16_RS04665	COG1683	Conserved Protein
ENC16_RS04670	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
ENC16_RS04680	COG0577	efflux transmembrane transporter activity
ENC16_RS04680	COG1136	(ABC) transporter
ENC16_RS04730	COG0518	GMP synthase (glutamine-hydrolyzing) activity
ENC16_RS04730	COG0519	Catalyzes the synthesis of GMP from XMP
ENC16_RS04735	COG0517	IMP dehydrogenase activity
ENC16_RS04735	COG0516	GMP reductase activity
ENC16_RS04740	COG2233	PERMEase
ENC16_RS04745	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
ENC16_RS04760	COG5183	chlorophyll binding
ENC16_RS04765	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ENC16_RS04770	COG1823	symporter activity
ENC16_RS04775	COG0778	Nitroreductase
ENC16_RS04780	COG0450	alkyl hydroperoxide reductase
ENC16_RS04790	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
ENC16_RS04795	COG5646	InterPro IPR014922
ENC16_RS04800	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
ENC16_RS04805	COG2011	ABC-type metal ion transport system permease component
ENC16_RS04810	COG1464	Belongs to the NlpA lipoprotein family
ENC16_RS04815	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
ENC16_RS04820	COG2814	Major facilitator Superfamily
ENC16_RS04830	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
ENC16_RS04840	COG0360	Binds together with S18 to 16S ribosomal RNA
ENC16_RS04855	COG0012	GTP binding
ENC16_RS04860	COG4481	Protein conserved in bacteria
ENC16_RS04865	COG0668	transmembrane transport
ENC16_RS04870	COG1475	DNA binding
ENC16_RS04875	COG0626	cystathionine gamma-synthase activity
ENC16_RS04880	COG0626	cystathionine gamma-synthase activity
ENC16_RS04885	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
ENC16_RS04885	COG0646	methionine synthase
ENC16_RS04900	COG0829	nickel cation binding
ENC16_RS04910	COG0830	nickel cation binding
ENC16_RS04915	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
ENC16_RS04920	COG2353	YceI-like domain
ENC16_RS04925	COG1846	Transcriptional regulator
ENC16_RS04930	COG0346	lactoylglutathione lyase activity
ENC16_RS04935	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
ENC16_RS04940	COG0400	carboxylic ester hydrolase activity
ENC16_RS04970	COG1475	DNA binding
ENC16_RS04975	COG0357	Ribosomal RNA small subunit methyltransferase G
ENC16_RS04980	COG0445	tRNA wobble uridine modification
ENC16_RS04985	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
ENC16_RS04990	COG0594	ribonuclease P activity
ENC16_RS05000	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
ENC16_RS05005	COG0592	DNA-directed DNA polymerase activity
ENC16_RS05015	COG2501	S4 domain
ENC16_RS05025	COG0187	DNA topoisomerase II activity
ENC16_RS05035	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
ENC16_RS05040	COG2986	histidine ammonia-lyase
ENC16_RS05050	COG2353	YceI-like domain
ENC16_RS05055	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
ENC16_RS05065	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
ENC16_RS05070	COG4241	membrane
ENC16_RS05075	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
ENC16_RS05080	COG0359	binds to the 23S rRNA
ENC16_RS05085	COG0305	Participates in initiation and elongation during chromosome replication
ENC16_RS05090	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
ENC16_RS05105	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
ENC16_RS05125	COG0745	RESPONSE REGULATOR receiver
ENC16_RS05130	COG5002	protein histidine kinase activity
ENC16_RS05135	COG4863	YycH protein
ENC16_RS05145	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
ENC16_RS05155	COG0747	negative chemotaxis
ENC16_RS05175	COG1124	(ABC) transporter
ENC16_RS05180	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
ENC16_RS05200	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ENC16_RS05200	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ENC16_RS05240	COG3425	synthase
ENC16_RS05250	COG0584	glycerophosphoryl diester phosphodiesterase
ENC16_RS05255	COG2030	dehydratase
ENC16_RS05335	COG2211	Major facilitator Superfamily
ENC16_RS05350	COG1136	(ABC) transporter
ENC16_RS05355	COG1609	Transcriptional regulator
ENC16_RS05360	COG1621	beta-fructofuranosidase activity
ENC16_RS05375	COG1250	3-hydroxyacyl-CoA dehydrogenase
ENC16_RS05380	COG0415	Belongs to the DNA photolyase family
ENC16_RS05395	COG2376	Dihydroxyacetone kinase
ENC16_RS05400	COG1461	Dihydroxyacetone kinase
ENC16_RS05405	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
ENC16_RS05415	COG0577	efflux transmembrane transporter activity
ENC16_RS05415	COG0577	efflux transmembrane transporter activity
ENC16_RS05420	COG1136	(ABC) transporter
ENC16_RS05425	COG2205	protein histidine kinase activity
ENC16_RS05430	COG0745	RESPONSE REGULATOR receiver
ENC16_RS05450	COG0753	catalase activity
ENC16_RS05455	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ENC16_RS05460	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ENC16_RS05465	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
ENC16_RS05475	COG2423	ornithine cyclodeaminase activity
ENC16_RS05480	COG4264	IucA IucC family
ENC16_RS05485	COG2814	Major facilitator Superfamily
ENC16_RS05490	COG4264	IucA IucC family
ENC16_RS05495	COG4264	IucA IucC family
ENC16_RS05505	COG0019	diaminopimelate decarboxylase activity
ENC16_RS05510	COG1475	DNA binding
ENC16_RS05515	COG0706	membrane insertase activity
ENC16_RS05525	COG1869	D-ribose catabolic process
ENC16_RS05530	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
ENC16_RS05540	COG1288	antiporter activity
ENC16_RS05580	COG2197	response regulator
ENC16_RS05585	COG4585	Histidine kinase
ENC16_RS05590	COG0842	Transport permease protein
ENC16_RS05595	COG1131	(ABC) transporter
ENC16_RS05640	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
ENC16_RS05670	COG1695	Transcriptional regulator
ENC16_RS05680	COG3477	response to acidic pH
ENC16_RS05695	COG1388	LysM domain
ENC16_RS05735	COG3711	transcriptional antiterminator
ENC16_RS05750	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ENC16_RS05770	COG2235	arginine
ENC16_RS05775	COG1438	arginine binding
ENC16_RS05785	COG4716	Myosin-crossreactive antigen
ENC16_RS05790	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
ENC16_RS05835	COG2188	Transcriptional regulator
ENC16_RS05870	COG2388	GCN5-related N-acetyl-transferase
ENC16_RS05880	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
ENC16_RS05900	COG2723	6-phospho-beta-galactosidase activity
ENC16_RS05905	COG2188	Transcriptional regulator
ENC16_RS05910	COG0492	ferredoxin-NADP+ reductase activity
ENC16_RS05915	COG1846	Transcriptional regulator
ENC16_RS05935	COG0346	lactoylglutathione lyase activity
ENC16_RS05945	COG1012	belongs to the aldehyde dehydrogenase family
ENC16_RS05945	COG1454	alcohol dehydrogenase
ENC16_RS05950	COG0471	metal ion transport
ENC16_RS05955	COG1827	regulation of RNA biosynthetic process
ENC16_RS05965	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
ENC16_RS05970	COG0157	Belongs to the NadC ModD family
ENC16_RS05975	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
ENC16_RS05990	COG0366	Alpha amylase catalytic
ENC16_RS05995	COG2188	Transcriptional regulator
ENC16_RS06000	COG2222	sugar isomerase
ENC16_RS06005	COG1105	Belongs to the carbohydrate kinase PfkB family
ENC16_RS06010	COG3684	Belongs to the aldolase LacD family
ENC16_RS06020	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ENC16_RS06020	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
ENC16_RS06025	COG3715	PTS system
ENC16_RS06030	COG3716	PTS system mannose fructose sorbose family IID component
ENC16_RS06040	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
ENC16_RS06060	COG3314	Sporulation integral membrane protein YlbJ
ENC16_RS06065	COG1414	Transcriptional regulator
ENC16_RS06070	COG0531	amino acid
ENC16_RS06095	COG1063	alcohol dehydrogenase
ENC16_RS06100	COG1620	l-lactate permease
ENC16_RS06110	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
ENC16_RS06135	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
ENC16_RS06140	COG2910	NAD(P)H-binding
ENC16_RS06145	COG2814	Major facilitator Superfamily
ENC16_RS06150	COG1335	isochorismatase
ENC16_RS06160	COG1063	alcohol dehydrogenase
ENC16_RS06175	COG2318	DinB family
ENC16_RS06180	COG0753	catalase activity
ENC16_RS06190	COG0783	Belongs to the Dps family
ENC16_RS06200	COG0436	Aminotransferase
ENC16_RS06220	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ENC16_RS06235	COG2814	Major facilitator Superfamily
ENC16_RS06240	COG2162	N-hydroxyarylamine O-acetyltransferase activity
ENC16_RS06250	COG1335	isochorismatase
ENC16_RS06280	COG0431	NADPH-dependent FMN reductase
ENC16_RS06290	COG4932	domain protein
ENC16_RS06295	COG0456	acetyltransferase
ENC16_RS06300	COG1755	Isoprenylcysteine carboxyl methyltransferase
ENC16_RS06315	COG0579	oxidoreductase
ENC16_RS06345	COG1073	alpha beta
ENC16_RS06365	COG0438	transferase activity, transferring glycosyl groups
ENC16_RS06370	COG0183	Belongs to the thiolase family
ENC16_RS06375	COG1024	Enoyl-CoA hydratase
ENC16_RS06375	COG1250	3-hydroxyacyl-CoA dehydrogenase
ENC16_RS06380	COG1960	acyl-CoA dehydrogenase activity
ENC16_RS06385	COG0318	PFAM AMP-dependent synthetase and ligase
ENC16_RS06400	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ENC16_RS06410	COG1116	anion transmembrane transporter activity
ENC16_RS06420	COG0563	adenylate kinase activity
ENC16_RS06430	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ENC16_RS06455	COG3711	transcriptional antiterminator
ENC16_RS06455	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ENC16_RS06460	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ENC16_RS06475	COG1328	CTP reductase activity
ENC16_RS06480	COG0602	queuosine metabolic process
ENC16_RS06495	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ENC16_RS06500	COG1942	4-Oxalocrotonate Tautomerase
ENC16_RS06515	COG0803	Belongs to the bacterial solute-binding protein 9 family
ENC16_RS06515	COG3443	Belongs to the bacterial solute-binding protein 9 family
ENC16_RS06525	COG3527	Alpha-acetolactate decarboxylase
ENC16_RS06540	COG4753	response regulator
ENC16_RS06540	COG2207	Transcriptional regulator
ENC16_RS06555	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
ENC16_RS06560	COG1210	Utp--glucose-1-phosphate uridylyltransferase
ENC16_RS06565	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
ENC16_RS06570	COG2211	Major facilitator Superfamily
ENC16_RS06575	COG1957	nucleoside hydrolase
ENC16_RS06585	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ENC16_RS06590	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
ENC16_RS06595	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
ENC16_RS06600	COG2807	transmembrane transport
ENC16_RS06605	COG1476	TRANSCRIPTIONal
ENC16_RS06610	COG0586	Pfam SNARE associated Golgi protein
ENC16_RS06625	COG1510	regulation of RNA biosynthetic process
ENC16_RS06630	COG1012	belongs to the aldehyde dehydrogenase family
ENC16_RS06635	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
ENC16_RS06650	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
ENC16_RS06655	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
ENC16_RS06660	COG0131	Imidazoleglycerol-phosphate dehydratase
ENC16_RS06665	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ENC16_RS06675	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
ENC16_RS06680	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
ENC16_RS06715	COG2376	Dihydroxyacetone kinase
ENC16_RS06720	COG1461	Dihydroxyacetone kinase
ENC16_RS06730	COG2824	Alkylphosphonate utilization operon protein PhnA
ENC16_RS06735	COG1012	belongs to the aldehyde dehydrogenase family
ENC16_RS06745	COG0596	Alpha beta hydrolase
ENC16_RS06755	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ENC16_RS06755	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ENC16_RS06755	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ENC16_RS06765	COG3942	CHAP domain
ENC16_RS06765	COG1705	Flagellar rod assembly protein muramidase FlgJ
ENC16_RS06775	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
ENC16_RS06790	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
ENC16_RS06795	COG0747	negative chemotaxis
ENC16_RS06820	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
ENC16_RS06820	COG0463	Glycosyl transferase, family 2
ENC16_RS06825	COG0438	transferase activity, transferring glycosyl groups
ENC16_RS06840	COG3181	Tripartite tricarboxylate transporter family receptor
ENC16_RS06845	COG0778	Nitroreductase
ENC16_RS06850	COG3001	Fructosamine kinase
ENC16_RS06870	COG1136	(ABC) transporter
ENC16_RS06875	COG0577	efflux transmembrane transporter activity
ENC16_RS06880	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
ENC16_RS06890	COG4413	Urea transporter
ENC16_RS06895	COG0831	urea catabolic process
ENC16_RS06900	COG0832	Belongs to the urease beta subunit family
ENC16_RS06905	COG0804	urea catabolic process
ENC16_RS06910	COG0717	Belongs to the dCTP deaminase family
ENC16_RS06915	COG0523	cobalamin synthesis protein
ENC16_RS06935	COG0583	DNA-binding transcription factor activity
ENC16_RS06945	COG1346	cytolysis
ENC16_RS06950	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ENC16_RS06955	COG4605	iron ion homeostasis
ENC16_RS06960	COG4604	ABC transporter, ATP-binding protein
ENC16_RS06965	COG4607	ABC-type enterochelin transport system periplasmic component
ENC16_RS06980	COG0778	Nitroreductase
ENC16_RS06985	COG2357	RelA SpoT domain protein
ENC16_RS06995	COG3942	CHAP domain
ENC16_RS07010	COG0596	Alpha beta hydrolase
ENC16_RS07035	COG1028	Short-chain dehydrogenase reductase Sdr
ENC16_RS07045	COG2816	NAD+ diphosphatase activity
ENC16_RS07055	COG3835	regulator
ENC16_RS07065	COG3961	Belongs to the TPP enzyme family
ENC16_RS07070	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
ENC16_RS07075	COG0512	Glutamine amidotransferase of anthranilate synthase
ENC16_RS07085	COG0134	indole-3-glycerol-phosphate synthase activity
ENC16_RS07090	COG0135	phosphoribosylanthranilate isomerase activity
ENC16_RS07095	COG0133	tryptophan synthase activity
ENC16_RS07100	COG0159	tryptophan synthase activity
ENC16_RS07115	COG1132	(ABC) transporter
ENC16_RS07120	COG1132	(ABC) transporter
ENC16_RS07130	COG1115	amino acid carrier protein
ENC16_RS07135	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
ENC16_RS07140	COG2814	Major facilitator Superfamily
ENC16_RS07145	COG2271	Major facilitator Superfamily
ENC16_RS07150	COG3764	Sortase (surface protein transpeptidase)
ENC16_RS07155	COG1929	Belongs to the glycerate kinase type-1 family
ENC16_RS07160	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
ENC16_RS07170	COG1174	glycine betaine transport
ENC16_RS07195	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
ENC16_RS07200	COG0702	epimerase
ENC16_RS07225	COG1760	l-serine dehydratase
ENC16_RS07255	COG0471	metal ion transport
ENC16_RS07270	COG0454	-acetyltransferase
ENC16_RS07285	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ENC16_RS07290	COG2146	nitrite reductase [NAD(P)H] activity
ENC16_RS07295	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
ENC16_RS07295	COG1648	precorrin-2 dehydrogenase activity
ENC16_RS07300	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
ENC16_RS07305	COG1140	nitrate reductase beta subunit
ENC16_RS07315	COG2181	nitrate reductase activity
ENC16_RS07325	COG4585	Histidine kinase
ENC16_RS07330	COG2197	response regulator
ENC16_RS07340	COG2223	nitrite transmembrane transporter activity
ENC16_RS07350	COG0039	L-malate dehydrogenase activity
ENC16_RS07355	COG1363	Peptidase, m42
ENC16_RS07370	COG2807	transmembrane transport
ENC16_RS07390	COG1283	sodium-dependent phosphate transmembrane transporter activity
ENC16_RS07410	COG0456	acetyltransferase
ENC16_RS07415	COG2814	Major facilitator Superfamily
ENC16_RS07420	COG0604	alcohol dehydrogenase
ENC16_RS07430	COG1620	l-lactate permease
ENC16_RS07440	COG0438	transferase activity, transferring glycosyl groups
ENC16_RS07490	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
ENC16_RS07500	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ENC16_RS07520	COG1304	FMN binding
ENC16_RS07525	COG0523	cobalamin synthesis protein
ENC16_RS07530	COG0786	glutamate:sodium symporter activity
ENC16_RS07535	COG2207	Transcriptional regulator
ENC16_RS07545	COG1695	Transcriptional regulator
ENC16_RS07560	COG1757	Na H antiporter
ENC16_RS07565	COG2094	Belongs to the DNA glycosylase MPG family
ENC16_RS07575	COG1288	antiporter activity
ENC16_RS07580	COG4152	abc transporter atp-binding protein
ENC16_RS07585	COG1668	transmembrane transport
ENC16_RS07590	COG1742	UPF0060 membrane protein
ENC16_RS07595	COG2017	converts alpha-aldose to the beta-anomer
ENC16_RS07600	COG1476	TRANSCRIPTIONal
ENC16_RS07605	COG2258	MOSC domain
ENC16_RS07610	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
ENC16_RS07615	COG1266	CAAX protease self-immunity
ENC16_RS07620	COG0010	Belongs to the arginase family
ENC16_RS07625	COG0583	DNA-binding transcription factor activity
ENC16_RS07630	COG3314	Sporulation integral membrane protein YlbJ
ENC16_RS07640	COG1228	amidohydrolase
ENC16_RS07645	COG0659	secondary active sulfate transmembrane transporter activity
ENC16_RS07650	COG1473	amidohydrolase
ENC16_RS07670	COG0385	Bile acid
ENC16_RS07700	COG1113	amino acid transport
ENC16_RS07725	COG1316	TRANSCRIPTIONal
ENC16_RS07740	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
ENC16_RS07745	COG3383	formate dehydrogenase (NAD+) activity
ENC16_RS07770	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ENC16_RS07775	COG2076	Multidrug Resistance protein
ENC16_RS07780	COG2076	Multidrug Resistance protein
ENC16_RS07795	COG1757	Na H antiporter
ENC16_RS07805	COG3942	CHAP domain
ENC16_RS07825	COG1960	acyl-CoA dehydrogenase activity
ENC16_RS07830	COG2832	Protein of unknown function (DUF454)
ENC16_RS07835	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
ENC16_RS07840	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ENC16_RS07850	COG2186	Transcriptional regulator
ENC16_RS07855	COG1940	carbohydrate kinase activity
ENC16_RS07860	COG1268	BioY protein
ENC16_RS07875	COG1609	Transcriptional regulator
ENC16_RS07880	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
ENC16_RS07885	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
ENC16_RS07890	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
ENC16_RS07895	COG0725	ABC transporter, periplasmic molybdate-binding protein
ENC16_RS07900	COG4149	molybdate abc transporter
ENC16_RS07905	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
ENC16_RS07910	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
ENC16_RS07915	COG0521	Mo-molybdopterin cofactor biosynthetic process
ENC16_RS07920	COG0315	cyclic pyranopterin monophosphate synthase activity
ENC16_RS07935	COG0314	molybdopterin synthase activity
ENC16_RS07945	COG0746	molybdenum cofactor guanylyltransferase activity
ENC16_RS07950	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
ENC16_RS07975	COG2348	transferase activity, transferring amino-acyl groups
ENC16_RS07980	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ENC16_RS07985	COG0436	Aminotransferase
ENC16_RS08010	COG2252	PERMEase
ENC16_RS08025	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
ENC16_RS08030	COG0088	Forms part of the polypeptide exit tunnel
ENC16_RS08035	COG0089	rRNA binding
ENC16_RS08040	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
ENC16_RS08045	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
ENC16_RS08050	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
ENC16_RS08055	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
ENC16_RS08065	COG0255	Belongs to the universal ribosomal protein uL29 family
ENC16_RS08075	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
ENC16_RS08080	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
ENC16_RS08085	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
ENC16_RS08090	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
ENC16_RS08095	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
ENC16_RS08115	COG1841	ribosomal large subunit assembly
ENC16_RS08125	COG0201	protein transport
ENC16_RS08140	COG0257	Belongs to the bacterial ribosomal protein bL36 family
ENC16_RS08150	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
ENC16_RS08155	COG0202	RNA polymerase activity
ENC16_RS08160	COG0203	ribosomal protein L17
ENC16_RS08165	COG1122	ATPase activity
ENC16_RS08170	COG1122	ATPase activity
ENC16_RS08180	COG0101	tRNA pseudouridine synthase activity
ENC16_RS08190	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
ENC16_RS08205	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
ENC16_RS08220	COG0018	arginyl-trna synthetase
ENC16_RS08230	COG0789	Transcriptional regulator
ENC16_RS08235	COG1335	isochorismatase
ENC16_RS08240	COG0488	(ABC) transporter
ENC16_RS08245	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ENC16_RS08250	COG0604	alcohol dehydrogenase
ENC16_RS08255	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
ENC16_RS08270	COG1302	Protein conserved in bacteria
ENC16_RS08275	COG2814	Major facilitator Superfamily
ENC16_RS08280	COG4264	IucA IucC family
ENC16_RS08285	COG2814	Major facilitator Superfamily
ENC16_RS08290	COG4264	IucA IucC family
ENC16_RS08295	COG3457	Alanine racemase
ENC16_RS08300	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
ENC16_RS08305	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ENC16_RS08310	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ENC16_RS08315	COG3314	Sporulation integral membrane protein YlbJ
ENC16_RS08325	COG1988	membrane-bound metal-dependent
ENC16_RS08330	COG4284	Utp--glucose-1-phosphate uridylyltransferase
ENC16_RS08335	COG1272	protein, Hemolysin III
ENC16_RS08355	COG2814	Major facilitator Superfamily
ENC16_RS08360	COG0489	protein tyrosine kinase activity
ENC16_RS08425	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ENC16_RS08445	COG2186	Transcriptional regulator
ENC16_RS08450	COG1482	cell wall glycoprotein biosynthetic process
ENC16_RS08475	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
ENC16_RS08505	COG5146	pantothenate kinase activity
ENC16_RS08515	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ENC16_RS08530	COG2271	Major facilitator Superfamily
ENC16_RS08535	COG4821	SIS domain
ENC16_RS08540	COG0191	fructose-bisphosphate aldolase activity
ENC16_RS08545	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
ENC16_RS08550	COG1733	regulation of RNA biosynthetic process
ENC16_RS08560	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
ENC16_RS08565	COG0254	rRNA binding
ENC16_RS08575	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
ENC16_RS08580	COG2890	protein-(glutamine-N5) methyltransferase activity
ENC16_RS08585	COG0009	L-threonylcarbamoyladenylate synthase
ENC16_RS08590	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ENC16_RS08595	COG4475	Protein of unknown function (DUF436)
ENC16_RS08600	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
ENC16_RS08605	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
ENC16_RS08610	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
ENC16_RS08620	COG0356	it plays a direct role in the translocation of protons across the membrane
ENC16_RS08625	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ENC16_RS08635	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ENC16_RS08645	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
ENC16_RS08665	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
ENC16_RS08675	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
ENC16_RS08690	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
ENC16_RS08700	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
ENC16_RS08705	COG0352	thiamine-phosphate diphosphorylase activity
ENC16_RS08710	COG0706	membrane insertase activity
ENC16_RS08725	COG1418	mRNA catabolic process
ENC16_RS08735	COG1937	Protein conserved in bacteria
ENC16_RS08750	COG2217	Heavy metal translocating P-type atpase
ENC16_RS08755	COG0772	Belongs to the SEDS family
ENC16_RS08760	COG1181	Belongs to the D-alanine--D-alanine ligase family
ENC16_RS08765	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
ENC16_RS08770	COG0513	Belongs to the DEAD box helicase family
ENC16_RS08790	COG0736	holo-[acyl-carrier-protein] synthase activity
ENC16_RS08795	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
ENC16_RS08805	COG2337	Toxic component of a toxin-antitoxin (TA) module
ENC16_RS08810	COG2208	phosphoserine phosphatase activity
ENC16_RS08815	COG1366	Belongs to the anti-sigma-factor antagonist family
ENC16_RS08825	COG1191	sigma factor activity
ENC16_RS08830	COG2183	response to ionizing radiation
ENC16_RS08835	COG3091	SprT-like family
ENC16_RS08865	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
ENC16_RS08875	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
ENC16_RS08885	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ENC16_RS08900	COG0028	Belongs to the TPP enzyme family
ENC16_RS08905	COG0129	dihydroxy-acid dehydratase activity
ENC16_RS08910	COG0802	atpase or kinase
ENC16_RS08915	COG1214	PFAM Peptidase M22, glycoprotease
ENC16_RS08920	COG0456	acetyltransferase
ENC16_RS08925	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
ENC16_RS08930	COG0488	(ABC) transporter
ENC16_RS08935	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
ENC16_RS08940	COG2391	methyltransferase activity
ENC16_RS08945	COG0425	Belongs to the sulfur carrier protein TusA family
ENC16_RS08950	COG1621	beta-fructofuranosidase activity
ENC16_RS08970	COG4512	PFAM Accessory gene regulator B
ENC16_RS09040	COG1464	Belongs to the NlpA lipoprotein family
ENC16_RS09045	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ENC16_RS09065	COG1131	(ABC) transporter
ENC16_RS09075	COG1802	Transcriptional regulator
ENC16_RS09080	COG1070	Carbohydrate kinase
ENC16_RS09085	COG2610	gluconate transmembrane transporter activity
ENC16_RS09120	COG2706	6-phosphogluconolactonase activity
ENC16_RS09125	COG1012	belongs to the aldehyde dehydrogenase family
ENC16_RS09135	COG1227	inorganic diphosphatase activity
ENC16_RS09140	COG1335	isochorismatase
ENC16_RS09160	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
ENC16_RS09165	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
ENC16_RS09170	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
ENC16_RS09180	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
ENC16_RS09185	COG4496	protein, YerC YecD
ENC16_RS09190	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
ENC16_RS09195	COG0210	DNA helicase
ENC16_RS09200	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
ENC16_RS09205	COG4851	CamS sex pheromone cAM373 precursor
ENC16_RS09210	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ENC16_RS09215	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ENC16_RS09220	COG0154	amidase activity
ENC16_RS09225	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ENC16_RS09235	COG1597	lipid kinase activity
ENC16_RS09240	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ENC16_RS09255	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
ENC16_RS09265	COG1528	Iron-storage protein
ENC16_RS09280	COG4129	membrane
ENC16_RS09285	COG0024	Methionine aminopeptidase
ENC16_RS09310	COG0288	reversible hydration of carbon dioxide
ENC16_RS09315	COG1295	ribonuclease BN
ENC16_RS09325	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ENC16_RS09330	COG4840	Belongs to the UPF0435 family
ENC16_RS09335	COG2309	aminopeptidase activity
ENC16_RS09340	COG1607	acyl-coa hydrolase
ENC16_RS09345	COG0535	radical SAM domain protein
ENC16_RS09350	COG0693	protein deglycase activity
ENC16_RS09355	COG0028	Belongs to the TPP enzyme family
ENC16_RS09375	COG2946	Replication initiation factor
ENC16_RS09395	COG0433	COG0433 Predicted ATPase
ENC16_RS09400	COG1674	ftsk spoiiie
ENC16_RS09430	COG2826	transposase and inactivated derivatives, IS30 family
ENC16_RS09435	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ENC16_RS09440	COG2137	regulation of response to DNA damage stimulus
ENC16_RS09450	COG1388	LysM domain
ENC16_RS09450	COG1134	teichoic acid transport
ENC16_RS09460	COG1988	membrane-bound metal-dependent
ENC16_RS09480	COG0069	glutamate synthase activity
ENC16_RS09485	COG4129	membrane
ENC16_RS09490	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
ENC16_RS09495	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
ENC16_RS09505	COG0735	belongs to the Fur family
ENC16_RS09655	COG1181	Belongs to the D-alanine--D-alanine ligase family
ENC16_RS09665	COG0765	amino acid transport
ENC16_RS09670	COG1126	abc transporter atp-binding protein
ENC16_RS09675	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
ENC16_RS09685	COG0363	glucosamine-6-phosphate deaminase activity
ENC16_RS09695	COG0114	fumarate hydratase activity
ENC16_RS09700	COG0248	Ppx GppA phosphatase
ENC16_RS09705	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
ENC16_RS09710	COG0564	pseudouridine synthase activity
ENC16_RS09715	COG4585	Histidine kinase
ENC16_RS09715	COG2203	Gaf domain
ENC16_RS09720	COG2197	response regulator
ENC16_RS09725	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
ENC16_RS09750	COG4399	Belongs to the UPF0754 family
ENC16_RS09755	COG3679	Belongs to the UPF0342 family
ENC16_RS09760	COG0420	3'-5' exonuclease activity
ENC16_RS09770	COG3481	metal-dependent phosphohydrolase, HD sub domain
ENC16_RS09775	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ENC16_RS09785	COG1846	Transcriptional regulator
ENC16_RS09795	COG0537	adenosine 5'-monophosphoramidase activity
ENC16_RS09800	COG1131	(ABC) transporter
ENC16_RS09805	COG4473	ABC transporter
ENC16_RS09815	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
ENC16_RS09820	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
ENC16_RS09825	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
ENC16_RS09830	COG3545	Serine hydrolase
ENC16_RS09925	COG0076	glutamate decarboxylase activity
ENC16_RS09945	COG0318	PFAM AMP-dependent synthetase and ligase
ENC16_RS09955	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
ENC16_RS09965	COG1506	peptidase
ENC16_RS09970	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
ENC16_RS09975	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
ENC16_RS09985	COG0656	L-ascorbic acid biosynthetic process
ENC16_RS09990	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
ENC16_RS10005	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
ENC16_RS10030	COG3266	domain, Protein
ENC16_RS10030	COG5632	N-Acetylmuramoyl-L-alanine amidase
ENC16_RS10030	COG4193	domain, Protein
ENC16_RS10045	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ENC16_RS10045	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ENC16_RS10055	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
ENC16_RS10055	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
ENC16_RS10060	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
ENC16_RS10065	COG0506	proline dehydrogenase activity
ENC16_RS10075	COG2267	carboxylic ester hydrolase activity
ENC16_RS10080	COG0039	L-malate dehydrogenase activity
ENC16_RS10090	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
ENC16_RS10095	COG1242	4 iron, 4 sulfur cluster binding
ENC16_RS10100	COG2814	Major facilitator Superfamily
ENC16_RS10105	COG0495	leucyl-tRNA aminoacylation
ENC16_RS10110	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ENC16_RS10115	COG2081	HI0933 family
ENC16_RS10120	COG2244	polysaccharide biosynthetic process
ENC16_RS10125	COG1187	pseudouridine synthase activity
ENC16_RS10135	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ENC16_RS10140	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
ENC16_RS10145	COG0510	thiamine kinase activity
ENC16_RS10150	COG0220	tRNA (guanine-N7-)-methyltransferase activity
ENC16_RS10155	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ENC16_RS10165	COG1363	Peptidase, m42
ENC16_RS10170	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ENC16_RS10180	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ENC16_RS10185	COG1674	ftsk spoiiie
ENC16_RS10190	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
ENC16_RS10195	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
ENC16_RS10205	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
ENC16_RS10205	COG1605	Chorismate mutase
ENC16_RS10210	COG1609	Transcriptional regulator
ENC16_RS10220	COG0454	-acetyltransferase
ENC16_RS10225	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ENC16_RS10230	COG2759	Belongs to the formate--tetrahydrofolate ligase family
ENC16_RS10235	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ENC16_RS10245	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ENC16_RS10250	COG0204	Acyl-transferase
ENC16_RS10260	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ENC16_RS10265	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
ENC16_RS10270	COG1764	response to oxidative stress
ENC16_RS10275	COG0584	glycerophosphoryl diester phosphodiesterase
ENC16_RS10285	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
ENC16_RS10290	COG1956	GAF domain-containing protein
ENC16_RS10295	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
ENC16_RS10300	COG1104	cysteine desulfurase activity
ENC16_RS10305	COG0301	tRNA thio-modification
ENC16_RS10315	COG0616	signal peptide processing
ENC16_RS10325	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
ENC16_RS10330	COG0827	DNA restriction-modification system
ENC16_RS10335	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
ENC16_RS10340	COG0589	response to stress
ENC16_RS10345	COG0686	Belongs to the AlaDH PNT family
ENC16_RS10355	COG0006	proline dipeptidase activity
ENC16_RS10360	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
ENC16_RS10370	COG4109	DRTGG domain
ENC16_RS10375	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
ENC16_RS10385	COG0281	malic enzyme
ENC16_RS10390	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
ENC16_RS10395	COG0825	malonyl-CoA metabolic process
ENC16_RS10400	COG0205	6-phosphofructokinase activity
ENC16_RS10405	COG0469	pyruvate kinase activity
ENC16_RS10410	COG0372	Belongs to the citrate synthase family
ENC16_RS10415	COG0538	isocitrate dehydrogenase activity
ENC16_RS10420	COG0745	RESPONSE REGULATOR receiver
ENC16_RS10425	COG5002	protein histidine kinase activity
ENC16_RS10430	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ENC16_RS10430	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ENC16_RS10440	COG0237	dephospho-CoA kinase activity
ENC16_RS10445	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
ENC16_RS10450	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
ENC16_RS10455	COG3611	Membrane attachment protein
ENC16_RS10460	COG1484	DNA-dependent DNA replication
ENC16_RS10470	COG0833	amino acid
ENC16_RS10475	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
ENC16_RS10480	COG0291	Belongs to the bacterial ribosomal protein bL35 family
ENC16_RS10490	COG4112	unkown
ENC16_RS10500	COG0544	peptidyl-prolyl cis-trans isomerase activity
ENC16_RS10505	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
ENC16_RS10510	COG0218	Necessary for normal cell division and for the maintenance of normal septation
ENC16_RS10515	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
ENC16_RS10520	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ENC16_RS10525	COG0181	hydroxymethylbilane synthase activity
ENC16_RS10535	COG0113	porphobilinogen synthase activity
ENC16_RS10540	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
ENC16_RS10550	COG2818	Glycosylase
ENC16_RS10555	COG0525	valine-tRNA ligase activity
ENC16_RS10560	COG0285	dihydrofolate synthase activity
ENC16_RS10570	COG2003	Belongs to the UPF0758 family
ENC16_RS10590	COG0261	This protein binds to 23S rRNA in the presence of protein L20
ENC16_RS10595	COG2868	ribosomal protein
ENC16_RS10610	COG4492	Belongs to the UPF0735 family
ENC16_RS10615	COG0632	four-way junction helicase activity
ENC16_RS10620	COG2255	four-way junction helicase activity
ENC16_RS10625	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
ENC16_RS10635	COG1862	Preprotein translocase
ENC16_RS10640	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ENC16_RS10640	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ENC16_RS10645	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
ENC16_RS10645	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
ENC16_RS10650	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
ENC16_RS10660	COG1490	D-aminoacyl-tRNA deacylase activity
ENC16_RS10665	COG0860	N-Acetylmuramoyl-L-alanine amidase
ENC16_RS10675	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
ENC16_RS10685	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
ENC16_RS10690	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
ENC16_RS10695	COG1959	2 iron, 2 sulfur cluster binding
ENC16_RS10710	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ENC16_RS10715	COG1104	cysteine desulfurase activity
ENC16_RS10720	COG0482	sulfurtransferase activity
ENC16_RS10730	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
ENC16_RS10735	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
ENC16_RS10740	COG4472	Bacterial protein of unknown function (DUF965)
ENC16_RS10745	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
ENC16_RS10750	COG3906	Belongs to the UPF0473 family
ENC16_RS10755	COG4122	O-methyltransferase activity
ENC16_RS10760	COG0826	peptidase U32
ENC16_RS10765	COG0826	peptidase U32
ENC16_RS10770	COG0572	uridine kinase
ENC16_RS10780	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
ENC16_RS10785	COG1984	allophanate hydrolase subunit 2
ENC16_RS10790	COG0511	ligase activity, forming carbon-carbon bonds
ENC16_RS10795	COG0439	Biotin carboxylase
ENC16_RS10800	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
ENC16_RS10805	COG1914	H( )-stimulated, divalent metal cation uptake system
ENC16_RS10810	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
ENC16_RS10815	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
ENC16_RS10820	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
ENC16_RS10825	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
ENC16_RS10830	COG1534	Rna-binding protein
ENC16_RS10840	COG1713	HD superfamily hydrolase involved in NAD metabolism
ENC16_RS10845	COG0799	negative regulation of ribosome biogenesis
ENC16_RS10850	COG2226	methyltransferase
ENC16_RS10855	COG1596	polysaccharide export
ENC16_RS10855	COG1555	photosystem II stabilization
ENC16_RS10860	COG2131	deaminase
ENC16_RS10870	COG1466	dna polymerase III delta subunit
ENC16_RS10875	COG0268	Binds directly to 16S ribosomal RNA
ENC16_RS10885	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ENC16_RS10890	COG1420	regulation of RNA biosynthetic process
ENC16_RS10905	COG0484	heat shock protein binding
ENC16_RS10910	COG2264	protein methyltransferase activity
ENC16_RS10915	COG1385	rRNA (uridine-N3-)-methyltransferase activity
ENC16_RS10920	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ENC16_RS10945	COG1702	phosphate starvation-inducible protein PhoH
ENC16_RS10950	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
ENC16_RS10955	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
ENC16_RS10960	COG0295	cytidine deaminase activity
ENC16_RS10970	COG1381	Involved in DNA repair and RecF pathway recombination
ENC16_RS10975	COG0423	glycine-tRNA ligase activity
ENC16_RS10980	COG0517	IMP dehydrogenase activity
ENC16_RS10985	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
ENC16_RS10990	COG0358	DNA primase activity
ENC16_RS10995	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ENC16_RS11000	COG2384	SAM-dependent methyltransferase
ENC16_RS11010	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
ENC16_RS11015	COG0513	Belongs to the DEAD box helicase family
ENC16_RS11020	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
ENC16_RS11025	COG1121	(ABC) transporter
ENC16_RS11030	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ENC16_RS11035	COG0735	belongs to the Fur family
ENC16_RS11040	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
ENC16_RS11050	COG0768	penicillin binding
ENC16_RS11055	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
ENC16_RS11060	COG0573	inorganic phosphate transmembrane transporter activity
ENC16_RS11065	COG0581	inorganic phosphate transmembrane transporter activity
ENC16_RS11070	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
ENC16_RS11075	COG0704	Plays a role in the regulation of phosphate uptake
ENC16_RS11080	COG0267	Belongs to the bacterial ribosomal protein bL33 family
ENC16_RS11085	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
ENC16_RS11090	COG0705	Rhomboid family
ENC16_RS11090	COG0457	Tetratricopeptide repeat
ENC16_RS11095	COG4483	Protein conserved in bacteria
ENC16_RS11100	COG1940	carbohydrate kinase activity
ENC16_RS11105	COG0011	TIGRFAM Protein of
ENC16_RS11110	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ENC16_RS11115	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
ENC16_RS11120	COG1459	type II secretion system
ENC16_RS11140	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
ENC16_RS11145	COG0404	The glycine cleavage system catalyzes the degradation of glycine
ENC16_RS11155	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
ENC16_RS11160	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ENC16_RS11165	COG0095	Lipoate-protein ligase
ENC16_RS11180	COG0006	proline dipeptidase activity
ENC16_RS11185	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
ENC16_RS11190	COG0511	ligase activity, forming carbon-carbon bonds
ENC16_RS11195	COG0439	Biotin carboxylase
ENC16_RS11200	COG1302	Protein conserved in bacteria
ENC16_RS11220	COG0142	geranyltranstransferase activity
ENC16_RS11225	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
ENC16_RS11230	COG1438	arginine binding
ENC16_RS11235	COG0497	DNA recombination
ENC16_RS11245	COG3426	butyrate kinase activity
ENC16_RS11250	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ENC16_RS11255	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
ENC16_RS11260	COG0022	dehydrogenase e1 component
ENC16_RS11265	COG0508	dehydrogenase complex catalyzes the overall conversion of
ENC16_RS11275	COG4129	membrane
ENC16_RS11280	COG2195	Cleaves the N-terminal amino acid of tripeptides
ENC16_RS11295	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
ENC16_RS11300	COG1234	tRNA 3'-trailer cleavage
ENC16_RS11305	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
ENC16_RS11315	COG0667	Aldo Keto reductase
ENC16_RS11320	COG0494	nUDIX hydrolase
ENC16_RS11325	COG0735	belongs to the Fur family
ENC16_RS11340	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
ENC16_RS11345	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
ENC16_RS11350	COG1187	pseudouridine synthase activity
ENC16_RS11355	COG0745	RESPONSE REGULATOR receiver
ENC16_RS11360	COG5002	protein histidine kinase activity
ENC16_RS11370	COG1141	Ferredoxin
ENC16_RS11380	COG0514	ATP-dependent DNA helicase (RecQ)
ENC16_RS11390	COG0492	ferredoxin-NADP+ reductase activity
ENC16_RS11400	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
ENC16_RS11405	COG0539	negative regulation of cytoplasmic translation
ENC16_RS11430	COG2226	methyltransferase
ENC16_RS11435	COG0142	geranyltranstransferase activity
ENC16_RS11440	COG0105	UTP biosynthetic process
ENC16_RS11450	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
ENC16_RS11460	COG0457	Tetratricopeptide repeat
ENC16_RS11465	COG5582	Belongs to the UPF0302 family
ENC16_RS11470	COG4347	Protein of unknown function (DUF1405)
ENC16_RS11475	COG2738	Putative neutral zinc metallopeptidase
ENC16_RS11480	COG1694	Mazg nucleotide pyrophosphohydrolase
ENC16_RS11485	COG0438	transferase activity, transferring glycosyl groups
ENC16_RS11500	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
ENC16_RS11500	COG1199	ATP-dependent helicase activity
ENC16_RS11505	COG0017	Asparaginyl-tRNA synthetase
ENC16_RS11510	COG3935	DnaD domain protein
ENC16_RS11515	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
ENC16_RS11525	COG4499	WXG100 protein secretion system (Wss), protein YukC
ENC16_RS11525	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ENC16_RS11530	COG3331	DNA recombination
ENC16_RS11540	COG4474	Belongs to the UPF0398 family
ENC16_RS11545	COG3599	regulation of cell shape
ENC16_RS11555	COG0116	Belongs to the methyltransferase superfamily
ENC16_RS11560	COG2962	Rard protein
ENC16_RS11565	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
ENC16_RS11570	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ENC16_RS11580	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
ENC16_RS11590	COG1413	lyase activity
ENC16_RS11600	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
ENC16_RS11625	COG2190	(PTS) system
ENC16_RS11630	COG4479	Belongs to the UPF0346 family
ENC16_RS11635	COG0793	Belongs to the peptidase S41A family
ENC16_RS11645	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
ENC16_RS11650	COG0671	phosphoesterase, PA-phosphatase related
ENC16_RS11660	COG5002	protein histidine kinase activity
ENC16_RS11665	COG0567	Dehydrogenase, E1 component
ENC16_RS11690	COG0714	Associated with various cellular activities
ENC16_RS11695	COG4548	von Willebrand factor, type A
ENC16_RS11700	COG1114	Component of the transport system for branched-chain amino acids
ENC16_RS11705	COG3853	Toxic anion resistance protein (TelA)
ENC16_RS11715	COG1254	Belongs to the acylphosphatase family
ENC16_RS11725	COG1278	Cold shock
ENC16_RS11740	COG1473	amidohydrolase
ENC16_RS11745	COG2171	N-acyltransferase activity
ENC16_RS11750	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
ENC16_RS11755	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ENC16_RS11760	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
ENC16_RS11765	COG0488	(ABC) transporter
ENC16_RS11770	COG2996	Protein conserved in bacteria
ENC16_RS11775	COG3711	transcriptional antiterminator
ENC16_RS11780	COG1447	Phosphotransferase system cellobiose-specific component IIA
ENC16_RS11915	COG0756	dUTP diphosphatase activity
ENC16_RS11970	COG4695	Portal protein
ENC16_RS12055	COG1388	LysM domain
ENC16_RS12055	COG0860	N-Acetylmuramoyl-L-alanine amidase
ENC16_RS12085	COG2723	6-phospho-beta-galactosidase activity
ENC16_RS12095	COG0698	ribose 5-phosphate isomerase
ENC16_RS12100	COG0698	ribose 5-phosphate isomerase
ENC16_RS12135	COG0287	Prephenate dehydrogenase
ENC16_RS12145	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
ENC16_RS12175	COG0628	permease
ENC16_RS12185	COG3711	transcriptional antiterminator
ENC16_RS12190	COG1115	amino acid carrier protein
ENC16_RS12195	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
ENC16_RS12200	COG0187	DNA topoisomerase II activity
ENC16_RS12210	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
ENC16_RS12215	COG4841	protein insertion into membrane
ENC16_RS12220	COG0824	Thioesterase
ENC16_RS12225	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
ENC16_RS12230	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
ENC16_RS12235	COG1970	mechanosensitive ion channel activity
ENC16_RS12250	COG4846	Membrane protein involved in cytochrome C biogenesis
ENC16_RS12255	COG3763	UPF0154 protein
ENC16_RS12265	COG4224	UPF0291 protein