locus-tag	class	description
SSCHL_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
SSCHL_RS00010	COG0592	DNA-directed DNA polymerase activity
SSCHL_RS00020	COG2501	S4 domain
SSCHL_RS00030	COG0187	DNA topoisomerase II activity
SSCHL_RS00040	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
SSCHL_RS00045	COG2986	histidine ammonia-lyase
SSCHL_RS00055	COG2353	YceI-like domain
SSCHL_RS00060	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
SSCHL_RS00070	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
SSCHL_RS00075	COG4241	membrane
SSCHL_RS00080	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
SSCHL_RS00085	COG0359	binds to the 23S rRNA
SSCHL_RS00090	COG0305	Participates in initiation and elongation during chromosome replication
SSCHL_RS00095	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
SSCHL_RS00110	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
SSCHL_RS00130	COG0745	RESPONSE REGULATOR receiver
SSCHL_RS00135	COG5002	protein histidine kinase activity
SSCHL_RS00140	COG4863	YycH protein
SSCHL_RS00150	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
SSCHL_RS00160	COG0747	negative chemotaxis
SSCHL_RS00175	COG0444	Belongs to the ABC transporter superfamily
SSCHL_RS00180	COG1124	(ABC) transporter
SSCHL_RS00185	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
SSCHL_RS00205	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SSCHL_RS00205	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SSCHL_RS00250	COG0584	glycerophosphoryl diester phosphodiesterase
SSCHL_RS00255	COG2030	dehydratase
SSCHL_RS00300	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
SSCHL_RS00335	COG3512	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
SSCHL_RS00340	COG1353	crispr-associated protein
SSCHL_RS00345	COG1421	Csm2 Type III-A
SSCHL_RS00350	COG1337	RAMP superfamily
SSCHL_RS00355	COG1567	CRISPR-associated RAMP protein, Csm4 family
SSCHL_RS00360	COG1332	CRISPR-associated RAMP protein, Csm5 family
SSCHL_RS00375	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
SSCHL_RS00400	COG2207	Transcriptional regulator
SSCHL_RS00410	COG2207	Transcriptional regulator
SSCHL_RS00435	COG1136	(ABC) transporter
SSCHL_RS00450	COG1609	Transcriptional regulator
SSCHL_RS00455	COG1621	beta-fructofuranosidase activity
SSCHL_RS00470	COG0415	Belongs to the DNA photolyase family
SSCHL_RS00475	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
SSCHL_RS00490	COG2376	Dihydroxyacetone kinase
SSCHL_RS00495	COG1461	Dihydroxyacetone kinase
SSCHL_RS00500	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
SSCHL_RS00520	COG2946	Replication initiation factor
SSCHL_RS00540	COG0433	COG0433 Predicted ATPase
SSCHL_RS00545	COG1674	ftsk spoiiie
SSCHL_RS00595	COG0753	catalase activity
SSCHL_RS00600	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SSCHL_RS00605	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SSCHL_RS00610	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
SSCHL_RS00620	COG2423	ornithine cyclodeaminase activity
SSCHL_RS00625	COG4264	IucA IucC family
SSCHL_RS00630	COG2814	Major facilitator Superfamily
SSCHL_RS00635	COG4264	IucA IucC family
SSCHL_RS00640	COG4264	IucA IucC family
SSCHL_RS00650	COG0019	diaminopimelate decarboxylase activity
SSCHL_RS00655	COG1475	DNA binding
SSCHL_RS00660	COG0706	membrane insertase activity
SSCHL_RS00670	COG1869	D-ribose catabolic process
SSCHL_RS00675	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
SSCHL_RS00685	COG1288	antiporter activity
SSCHL_RS00700	COG1309	transcriptional regulator
SSCHL_RS00725	COG2197	response regulator
SSCHL_RS00730	COG4585	Histidine kinase
SSCHL_RS00735	COG0842	Transport permease protein
SSCHL_RS00740	COG1131	(ABC) transporter
SSCHL_RS00750	COG1737	Transcriptional regulator
SSCHL_RS00755	COG1263	PTS System
SSCHL_RS00755	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SSCHL_RS00760	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
SSCHL_RS00805	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
SSCHL_RS00835	COG1695	Transcriptional regulator
SSCHL_RS00845	COG3477	response to acidic pH
SSCHL_RS00860	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SSCHL_RS00880	COG2235	arginine
SSCHL_RS00885	COG1438	arginine binding
SSCHL_RS00895	COG4716	Myosin-crossreactive antigen
SSCHL_RS00900	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
SSCHL_RS00945	COG2188	Transcriptional regulator
SSCHL_RS00985	COG2388	GCN5-related N-acetyl-transferase
SSCHL_RS00995	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
SSCHL_RS01020	COG2723	6-phospho-beta-galactosidase activity
SSCHL_RS01025	COG2188	Transcriptional regulator
SSCHL_RS01030	COG0492	ferredoxin-NADP+ reductase activity
SSCHL_RS01035	COG1846	Transcriptional regulator
SSCHL_RS01040	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SSCHL_RS01050	COG0346	lactoylglutathione lyase activity
SSCHL_RS01055	COG1454	alcohol dehydrogenase
SSCHL_RS01055	COG1012	belongs to the aldehyde dehydrogenase family
SSCHL_RS01060	COG0471	metal ion transport
SSCHL_RS01065	COG1827	regulation of RNA biosynthetic process
SSCHL_RS01075	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
SSCHL_RS01080	COG0157	Belongs to the NadC ModD family
SSCHL_RS01085	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
SSCHL_RS01105	COG0366	Alpha amylase catalytic
SSCHL_RS01110	COG2188	Transcriptional regulator
SSCHL_RS01115	COG2222	sugar isomerase
SSCHL_RS01120	COG1105	Belongs to the carbohydrate kinase PfkB family
SSCHL_RS01125	COG3684	Belongs to the aldolase LacD family
SSCHL_RS01135	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SSCHL_RS01135	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
SSCHL_RS01140	COG3715	PTS system
SSCHL_RS01145	COG3716	PTS system mannose fructose sorbose family IID component
SSCHL_RS01155	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
SSCHL_RS01175	COG3314	Sporulation integral membrane protein YlbJ
SSCHL_RS01185	COG0531	amino acid
SSCHL_RS01200	COG1476	TRANSCRIPTIONal
SSCHL_RS01210	COG1063	alcohol dehydrogenase
SSCHL_RS01215	COG1620	l-lactate permease
SSCHL_RS01220	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
SSCHL_RS01225	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
SSCHL_RS01250	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
SSCHL_RS01255	COG2910	NAD(P)H-binding
SSCHL_RS01260	COG2814	Major facilitator Superfamily
SSCHL_RS01265	COG1335	isochorismatase
SSCHL_RS01275	COG1063	alcohol dehydrogenase
SSCHL_RS01295	COG2318	DinB family
SSCHL_RS01300	COG0753	catalase activity
SSCHL_RS01310	COG0783	Belongs to the Dps family
SSCHL_RS01320	COG0436	Aminotransferase
SSCHL_RS01340	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SSCHL_RS01355	COG2814	Major facilitator Superfamily
SSCHL_RS01360	COG2162	N-hydroxyarylamine O-acetyltransferase activity
SSCHL_RS01370	COG1335	isochorismatase
SSCHL_RS01380	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
SSCHL_RS01380	COG3266	domain, Protein
SSCHL_RS01380	COG4932	domain protein
SSCHL_RS01385	COG0431	NADPH-dependent FMN reductase
SSCHL_RS01395	COG4932	domain protein
SSCHL_RS01400	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
SSCHL_RS01400	COG3266	domain, Protein
SSCHL_RS01400	COG4932	domain protein
SSCHL_RS01405	COG0456	acetyltransferase
SSCHL_RS01410	COG1755	Isoprenylcysteine carboxyl methyltransferase
SSCHL_RS01415	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
SSCHL_RS01420	COG0579	oxidoreductase
SSCHL_RS01455	COG1073	alpha beta
SSCHL_RS01475	COG0438	transferase activity, transferring glycosyl groups
SSCHL_RS01480	COG0183	Belongs to the thiolase family
SSCHL_RS01485	COG1250	3-hydroxyacyl-CoA dehydrogenase
SSCHL_RS01485	COG1024	Enoyl-CoA hydratase
SSCHL_RS01490	COG1960	acyl-CoA dehydrogenase activity
SSCHL_RS01495	COG0318	PFAM AMP-dependent synthetase and ligase
SSCHL_RS01510	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
SSCHL_RS01520	COG1116	anion transmembrane transporter activity
SSCHL_RS01530	COG0563	adenylate kinase activity
SSCHL_RS01540	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SSCHL_RS01565	COG3711	transcriptional antiterminator
SSCHL_RS01570	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SSCHL_RS01580	COG3037	sugar-specific permease SgaT UlaA
SSCHL_RS01585	COG1328	CTP reductase activity
SSCHL_RS01590	COG0602	queuosine metabolic process
SSCHL_RS01605	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
SSCHL_RS01610	COG1942	4-Oxalocrotonate Tautomerase
SSCHL_RS01625	COG0803	Belongs to the bacterial solute-binding protein 9 family
SSCHL_RS01625	COG3443	Belongs to the bacterial solute-binding protein 9 family
SSCHL_RS01650	COG4753	response regulator
SSCHL_RS01650	COG2207	Transcriptional regulator
SSCHL_RS01670	COG1210	Utp--glucose-1-phosphate uridylyltransferase
SSCHL_RS01675	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
SSCHL_RS01680	COG2211	Major facilitator Superfamily
SSCHL_RS01685	COG1957	nucleoside hydrolase
SSCHL_RS01695	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
SSCHL_RS01700	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
SSCHL_RS01705	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
SSCHL_RS01710	COG2807	transmembrane transport
SSCHL_RS01715	COG1476	TRANSCRIPTIONal
SSCHL_RS01720	COG0586	Pfam SNARE associated Golgi protein
SSCHL_RS01735	COG1510	regulation of RNA biosynthetic process
SSCHL_RS01740	COG1012	belongs to the aldehyde dehydrogenase family
SSCHL_RS01745	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
SSCHL_RS01760	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
SSCHL_RS01765	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
SSCHL_RS01770	COG0131	Imidazoleglycerol-phosphate dehydratase
SSCHL_RS01775	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
SSCHL_RS01785	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
SSCHL_RS01790	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
SSCHL_RS01825	COG2376	Dihydroxyacetone kinase
SSCHL_RS01830	COG1461	Dihydroxyacetone kinase
SSCHL_RS01840	COG2824	Alkylphosphonate utilization operon protein PhnA
SSCHL_RS01845	COG1012	belongs to the aldehyde dehydrogenase family
SSCHL_RS01855	COG0596	Alpha beta hydrolase
SSCHL_RS01865	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SSCHL_RS01865	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SSCHL_RS01865	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SSCHL_RS01875	COG3942	CHAP domain
SSCHL_RS01875	COG1705	Flagellar rod assembly protein muramidase FlgJ
SSCHL_RS01885	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
SSCHL_RS01900	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
SSCHL_RS01905	COG0747	negative chemotaxis
SSCHL_RS01930	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
SSCHL_RS01930	COG0463	Glycosyl transferase, family 2
SSCHL_RS01950	COG3181	Tripartite tricarboxylate transporter family receptor
SSCHL_RS01955	COG0778	Nitroreductase
SSCHL_RS01960	COG3001	Fructosamine kinase
SSCHL_RS01980	COG1136	(ABC) transporter
SSCHL_RS01985	COG0577	efflux transmembrane transporter activity
SSCHL_RS02000	COG4413	Urea transporter
SSCHL_RS02005	COG0831	urea catabolic process
SSCHL_RS02010	COG0832	Belongs to the urease beta subunit family
SSCHL_RS02015	COG0804	urea catabolic process
SSCHL_RS02020	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
SSCHL_RS02025	COG1063	alcohol dehydrogenase
SSCHL_RS02030	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
SSCHL_RS02035	COG0717	Belongs to the dCTP deaminase family
SSCHL_RS02040	COG0523	cobalamin synthesis protein
SSCHL_RS02055	COG0583	DNA-binding transcription factor activity
SSCHL_RS02065	COG1346	cytolysis
SSCHL_RS02070	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SSCHL_RS02075	COG4605	iron ion homeostasis
SSCHL_RS02080	COG4604	ABC transporter, ATP-binding protein
SSCHL_RS02085	COG4607	ABC-type enterochelin transport system periplasmic component
SSCHL_RS02100	COG0778	Nitroreductase
SSCHL_RS02105	COG2357	RelA SpoT domain protein
SSCHL_RS02115	COG3942	CHAP domain
SSCHL_RS02130	COG0596	Alpha beta hydrolase
SSCHL_RS02155	COG1028	Short-chain dehydrogenase reductase Sdr
SSCHL_RS02165	COG2816	NAD+ diphosphatase activity
SSCHL_RS02175	COG3835	regulator
SSCHL_RS02185	COG3961	Belongs to the TPP enzyme family
SSCHL_RS02190	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
SSCHL_RS02195	COG0512	Glutamine amidotransferase of anthranilate synthase
SSCHL_RS02205	COG0134	indole-3-glycerol-phosphate synthase activity
SSCHL_RS02210	COG0135	phosphoribosylanthranilate isomerase activity
SSCHL_RS02215	COG0133	tryptophan synthase activity
SSCHL_RS02220	COG0159	tryptophan synthase activity
SSCHL_RS02235	COG1132	(ABC) transporter
SSCHL_RS02240	COG1132	(ABC) transporter
SSCHL_RS02250	COG1115	amino acid carrier protein
SSCHL_RS02255	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
SSCHL_RS02260	COG2814	Major facilitator Superfamily
SSCHL_RS02265	COG2271	Major facilitator Superfamily
SSCHL_RS02270	COG3764	Sortase (surface protein transpeptidase)
SSCHL_RS02275	COG1929	Belongs to the glycerate kinase type-1 family
SSCHL_RS02290	COG1174	glycine betaine transport
SSCHL_RS02315	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
SSCHL_RS02325	COG0747	negative chemotaxis
SSCHL_RS02335	COG4608	Belongs to the ABC transporter superfamily
SSCHL_RS02340	COG0601	transmembrane transport
SSCHL_RS02345	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SSCHL_RS02360	COG1760	l-serine dehydratase
SSCHL_RS02365	COG1760	l-serine dehydratase
SSCHL_RS02395	COG0471	metal ion transport
SSCHL_RS02410	COG0454	-acetyltransferase
SSCHL_RS02425	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
SSCHL_RS02430	COG2146	nitrite reductase [NAD(P)H] activity
SSCHL_RS02435	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
SSCHL_RS02435	COG1648	precorrin-2 dehydrogenase activity
SSCHL_RS02440	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
SSCHL_RS02445	COG1140	nitrate reductase beta subunit
SSCHL_RS02455	COG2181	nitrate reductase activity
SSCHL_RS02465	COG4585	Histidine kinase
SSCHL_RS02470	COG2197	response regulator
SSCHL_RS02480	COG2223	nitrite transmembrane transporter activity
SSCHL_RS02490	COG0039	L-malate dehydrogenase activity
SSCHL_RS02495	COG1363	Peptidase, m42
SSCHL_RS02510	COG2807	transmembrane transport
SSCHL_RS02530	COG1283	sodium-dependent phosphate transmembrane transporter activity
SSCHL_RS02555	COG2814	Major facilitator Superfamily
SSCHL_RS02560	COG0604	alcohol dehydrogenase
SSCHL_RS02570	COG1620	l-lactate permease
SSCHL_RS02595	COG0438	transferase activity, transferring glycosyl groups
SSCHL_RS02625	COG1434	Gram-negative-bacterium-type cell wall biogenesis
SSCHL_RS02645	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
SSCHL_RS02655	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
SSCHL_RS02675	COG1304	FMN binding
SSCHL_RS02680	COG0523	cobalamin synthesis protein
SSCHL_RS02685	COG0786	glutamate:sodium symporter activity
SSCHL_RS02690	COG2207	Transcriptional regulator
SSCHL_RS02700	COG1695	Transcriptional regulator
SSCHL_RS02715	COG1757	Na H antiporter
SSCHL_RS02720	COG2094	Belongs to the DNA glycosylase MPG family
SSCHL_RS02730	COG1288	antiporter activity
SSCHL_RS02735	COG4152	abc transporter atp-binding protein
SSCHL_RS02740	COG1668	transmembrane transport
SSCHL_RS02745	COG1742	UPF0060 membrane protein
SSCHL_RS02750	COG2017	converts alpha-aldose to the beta-anomer
SSCHL_RS02755	COG1476	TRANSCRIPTIONal
SSCHL_RS02760	COG2258	MOSC domain
SSCHL_RS02765	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
SSCHL_RS02775	COG1266	CAAX protease self-immunity
SSCHL_RS02780	COG0010	Belongs to the arginase family
SSCHL_RS02785	COG0583	DNA-binding transcription factor activity
SSCHL_RS02790	COG3314	Sporulation integral membrane protein YlbJ
SSCHL_RS02800	COG1228	amidohydrolase
SSCHL_RS02810	COG1473	amidohydrolase
SSCHL_RS02830	COG0385	Bile acid
SSCHL_RS02860	COG1113	amino acid transport
SSCHL_RS02885	COG1316	TRANSCRIPTIONal
SSCHL_RS02900	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
SSCHL_RS02905	COG3383	formate dehydrogenase (NAD+) activity
SSCHL_RS02930	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
SSCHL_RS02935	COG2076	Multidrug Resistance protein
SSCHL_RS02940	COG2076	Multidrug Resistance protein
SSCHL_RS02955	COG1757	Na H antiporter
SSCHL_RS02965	COG3942	CHAP domain
SSCHL_RS02985	COG1960	acyl-CoA dehydrogenase activity
SSCHL_RS02995	COG2832	Protein of unknown function (DUF454)
SSCHL_RS03000	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
SSCHL_RS03005	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
SSCHL_RS03015	COG2186	Transcriptional regulator
SSCHL_RS03020	COG1940	carbohydrate kinase activity
SSCHL_RS03025	COG1268	BioY protein
SSCHL_RS03040	COG1609	Transcriptional regulator
SSCHL_RS03045	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
SSCHL_RS03050	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
SSCHL_RS03055	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
SSCHL_RS03060	COG0725	ABC transporter, periplasmic molybdate-binding protein
SSCHL_RS03065	COG4149	molybdate abc transporter
SSCHL_RS03070	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
SSCHL_RS03075	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
SSCHL_RS03080	COG0521	Mo-molybdopterin cofactor biosynthetic process
SSCHL_RS03085	COG0315	cyclic pyranopterin monophosphate synthase activity
SSCHL_RS03100	COG0314	molybdopterin synthase activity
SSCHL_RS03110	COG0746	molybdenum cofactor guanylyltransferase activity
SSCHL_RS03115	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
SSCHL_RS03140	COG2348	transferase activity, transferring amino-acyl groups
SSCHL_RS03145	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
SSCHL_RS03150	COG0436	Aminotransferase
SSCHL_RS03175	COG2252	PERMEase
SSCHL_RS03190	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
SSCHL_RS03195	COG0088	Forms part of the polypeptide exit tunnel
SSCHL_RS03200	COG0089	rRNA binding
SSCHL_RS03205	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
SSCHL_RS03210	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
SSCHL_RS03215	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
SSCHL_RS03220	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
SSCHL_RS03230	COG0255	Belongs to the universal ribosomal protein uL29 family
SSCHL_RS03240	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
SSCHL_RS03245	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
SSCHL_RS03250	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
SSCHL_RS03255	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
SSCHL_RS03260	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
SSCHL_RS03280	COG1841	ribosomal large subunit assembly
SSCHL_RS03290	COG0201	protein transport
SSCHL_RS03305	COG0257	Belongs to the bacterial ribosomal protein bL36 family
SSCHL_RS03315	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
SSCHL_RS03320	COG0202	RNA polymerase activity
SSCHL_RS03325	COG0203	ribosomal protein L17
SSCHL_RS03330	COG1122	ATPase activity
SSCHL_RS03335	COG1122	ATPase activity
SSCHL_RS03345	COG0101	tRNA pseudouridine synthase activity
SSCHL_RS03355	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
SSCHL_RS03370	COG0018	arginyl-trna synthetase
SSCHL_RS03380	COG0789	Transcriptional regulator
SSCHL_RS03385	COG1335	isochorismatase
SSCHL_RS03390	COG0488	(ABC) transporter
SSCHL_RS03395	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SSCHL_RS03400	COG0604	alcohol dehydrogenase
SSCHL_RS03420	COG1302	Protein conserved in bacteria
SSCHL_RS03425	COG2814	Major facilitator Superfamily
SSCHL_RS03430	COG4264	IucA IucC family
SSCHL_RS03435	COG2814	Major facilitator Superfamily
SSCHL_RS03440	COG4264	IucA IucC family
SSCHL_RS03445	COG3457	Alanine racemase
SSCHL_RS03450	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
SSCHL_RS03455	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SSCHL_RS03460	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SSCHL_RS03465	COG3314	Sporulation integral membrane protein YlbJ
SSCHL_RS03475	COG1988	membrane-bound metal-dependent
SSCHL_RS03480	COG4284	Utp--glucose-1-phosphate uridylyltransferase
SSCHL_RS03485	COG1272	protein, Hemolysin III
SSCHL_RS03505	COG2814	Major facilitator Superfamily
SSCHL_RS03510	COG0489	protein tyrosine kinase activity
SSCHL_RS03575	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
SSCHL_RS03600	COG2186	Transcriptional regulator
SSCHL_RS03605	COG1482	cell wall glycoprotein biosynthetic process
SSCHL_RS03630	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
SSCHL_RS03660	COG5146	pantothenate kinase activity
SSCHL_RS03670	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
SSCHL_RS03685	COG2271	Major facilitator Superfamily
SSCHL_RS03690	COG4821	SIS domain
SSCHL_RS03695	COG0191	fructose-bisphosphate aldolase activity
SSCHL_RS03700	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
SSCHL_RS03705	COG1733	regulation of RNA biosynthetic process
SSCHL_RS03715	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
SSCHL_RS03720	COG0254	rRNA binding
SSCHL_RS03730	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
SSCHL_RS03735	COG2890	protein-(glutamine-N5) methyltransferase activity
SSCHL_RS03740	COG0009	L-threonylcarbamoyladenylate synthase
SSCHL_RS03745	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
SSCHL_RS03755	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
SSCHL_RS03760	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
SSCHL_RS03765	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
SSCHL_RS03775	COG0356	it plays a direct role in the translocation of protons across the membrane
SSCHL_RS03780	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
SSCHL_RS03790	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
SSCHL_RS03795	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
SSCHL_RS03800	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
SSCHL_RS03820	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
SSCHL_RS03830	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
SSCHL_RS03845	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
SSCHL_RS03855	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
SSCHL_RS03860	COG0352	thiamine-phosphate diphosphorylase activity
SSCHL_RS03865	COG0706	membrane insertase activity
SSCHL_RS03880	COG1418	mRNA catabolic process
SSCHL_RS03890	COG1937	Protein conserved in bacteria
SSCHL_RS03905	COG2217	Heavy metal translocating P-type atpase
SSCHL_RS03910	COG0772	Belongs to the SEDS family
SSCHL_RS03915	COG1181	Belongs to the D-alanine--D-alanine ligase family
SSCHL_RS03920	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
SSCHL_RS03925	COG0513	Belongs to the DEAD box helicase family
SSCHL_RS03945	COG0736	holo-[acyl-carrier-protein] synthase activity
SSCHL_RS03950	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
SSCHL_RS03960	COG2337	Toxic component of a toxin-antitoxin (TA) module
SSCHL_RS03965	COG2208	phosphoserine phosphatase activity
SSCHL_RS03970	COG1366	Belongs to the anti-sigma-factor antagonist family
SSCHL_RS03980	COG1191	sigma factor activity
SSCHL_RS03985	COG2183	response to ionizing radiation
SSCHL_RS03990	COG3091	SprT-like family
SSCHL_RS04020	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
SSCHL_RS04030	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
SSCHL_RS04040	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
SSCHL_RS04055	COG0028	Belongs to the TPP enzyme family
SSCHL_RS04060	COG0129	dihydroxy-acid dehydratase activity
SSCHL_RS04065	COG0802	atpase or kinase
SSCHL_RS04070	COG1214	PFAM Peptidase M22, glycoprotease
SSCHL_RS04075	COG0456	acetyltransferase
SSCHL_RS04080	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
SSCHL_RS04085	COG0488	(ABC) transporter
SSCHL_RS04090	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
SSCHL_RS04095	COG2391	methyltransferase activity
SSCHL_RS04100	COG0425	Belongs to the sulfur carrier protein TusA family
SSCHL_RS04105	COG1621	beta-fructofuranosidase activity
SSCHL_RS04130	COG4512	PFAM Accessory gene regulator B
SSCHL_RS04160	COG0582	viral genome integration into host DNA
SSCHL_RS04265	COG1464	Belongs to the NlpA lipoprotein family
SSCHL_RS04270	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
SSCHL_RS04290	COG1131	(ABC) transporter
SSCHL_RS04300	COG1802	Transcriptional regulator
SSCHL_RS04305	COG1070	Carbohydrate kinase
SSCHL_RS04310	COG2610	gluconate transmembrane transporter activity
SSCHL_RS04345	COG2706	6-phosphogluconolactonase activity
SSCHL_RS04350	COG1012	belongs to the aldehyde dehydrogenase family
SSCHL_RS04360	COG1227	inorganic diphosphatase activity
SSCHL_RS04365	COG1335	isochorismatase
SSCHL_RS04375	COG0077	Prephenate dehydratase
SSCHL_RS04385	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
SSCHL_RS04390	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
SSCHL_RS04395	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
SSCHL_RS04400	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
SSCHL_RS04405	COG4496	protein, YerC YecD
SSCHL_RS04410	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
SSCHL_RS04415	COG0210	DNA helicase
SSCHL_RS04420	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
SSCHL_RS04425	COG4851	CamS sex pheromone cAM373 precursor
SSCHL_RS04430	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
SSCHL_RS04435	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
SSCHL_RS04440	COG0154	amidase activity
SSCHL_RS04445	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
SSCHL_RS04455	COG1597	lipid kinase activity
SSCHL_RS04460	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
SSCHL_RS04475	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
SSCHL_RS04485	COG1528	Iron-storage protein
SSCHL_RS04500	COG4129	membrane
SSCHL_RS04505	COG0024	Methionine aminopeptidase
SSCHL_RS04530	COG0288	reversible hydration of carbon dioxide
SSCHL_RS04535	COG1295	ribonuclease BN
SSCHL_RS04545	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
SSCHL_RS04550	COG4840	Belongs to the UPF0435 family
SSCHL_RS04555	COG2309	aminopeptidase activity
SSCHL_RS04560	COG1607	acyl-coa hydrolase
SSCHL_RS04565	COG0535	radical SAM domain protein
SSCHL_RS04570	COG0693	protein deglycase activity
SSCHL_RS04575	COG0028	Belongs to the TPP enzyme family
SSCHL_RS04580	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SSCHL_RS04585	COG2137	regulation of response to DNA damage stimulus
SSCHL_RS04595	COG1388	LysM domain
SSCHL_RS04595	COG1134	teichoic acid transport
SSCHL_RS04605	COG1988	membrane-bound metal-dependent
SSCHL_RS04625	COG0069	glutamate synthase activity
SSCHL_RS04630	COG4129	membrane
SSCHL_RS04635	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
SSCHL_RS04640	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
SSCHL_RS04650	COG0735	belongs to the Fur family
SSCHL_RS04805	COG0765	amino acid transport
SSCHL_RS04810	COG1126	abc transporter atp-binding protein
SSCHL_RS04815	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
SSCHL_RS04835	COG0114	fumarate hydratase activity
SSCHL_RS04845	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
SSCHL_RS04850	COG0564	pseudouridine synthase activity
SSCHL_RS04855	COG4585	Histidine kinase
SSCHL_RS04855	COG2203	Gaf domain
SSCHL_RS04860	COG2197	response regulator
SSCHL_RS04865	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
SSCHL_RS04890	COG4399	Belongs to the UPF0754 family
SSCHL_RS04895	COG3679	Belongs to the UPF0342 family
SSCHL_RS04900	COG0420	3'-5' exonuclease activity
SSCHL_RS04910	COG3481	metal-dependent phosphohydrolase, HD sub domain
SSCHL_RS04915	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
SSCHL_RS04925	COG1846	Transcriptional regulator
SSCHL_RS04935	COG0537	adenosine 5'-monophosphoramidase activity
SSCHL_RS04940	COG1131	(ABC) transporter
SSCHL_RS04945	COG4473	ABC transporter
SSCHL_RS04955	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
SSCHL_RS04960	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
SSCHL_RS04965	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
SSCHL_RS04970	COG3545	Serine hydrolase
SSCHL_RS05080	COG0076	glutamate decarboxylase activity
SSCHL_RS05085	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
SSCHL_RS05085	COG3266	domain, Protein
SSCHL_RS05085	COG4932	domain protein
SSCHL_RS05100	COG0318	PFAM AMP-dependent synthetase and ligase
SSCHL_RS05110	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
SSCHL_RS05120	COG1506	peptidase
SSCHL_RS05125	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
SSCHL_RS05130	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
SSCHL_RS05140	COG0656	L-ascorbic acid biosynthetic process
SSCHL_RS05145	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
SSCHL_RS05160	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
SSCHL_RS05185	COG4193	domain, Protein
SSCHL_RS05185	COG5632	N-Acetylmuramoyl-L-alanine amidase
SSCHL_RS05185	COG3266	domain, Protein
SSCHL_RS05200	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
SSCHL_RS05200	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
SSCHL_RS05210	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
SSCHL_RS05210	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
SSCHL_RS05215	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
SSCHL_RS05220	COG0506	proline dehydrogenase activity
SSCHL_RS05230	COG2267	carboxylic ester hydrolase activity
SSCHL_RS05235	COG0039	L-malate dehydrogenase activity
SSCHL_RS05250	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
SSCHL_RS05255	COG1242	4 iron, 4 sulfur cluster binding
SSCHL_RS05260	COG2814	Major facilitator Superfamily
SSCHL_RS05265	COG0495	leucyl-tRNA aminoacylation
SSCHL_RS05270	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
SSCHL_RS05275	COG2081	HI0933 family
SSCHL_RS05280	COG2244	polysaccharide biosynthetic process
SSCHL_RS05285	COG1187	pseudouridine synthase activity
SSCHL_RS05295	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
SSCHL_RS05300	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
SSCHL_RS05305	COG0510	thiamine kinase activity
SSCHL_RS05310	COG0220	tRNA (guanine-N7-)-methyltransferase activity
SSCHL_RS05315	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
SSCHL_RS05325	COG1363	Peptidase, m42
SSCHL_RS05330	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
SSCHL_RS05335	COG4848	Belongs to the UPF0354 family
SSCHL_RS05340	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SSCHL_RS05345	COG1674	ftsk spoiiie
SSCHL_RS05350	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
SSCHL_RS05355	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
SSCHL_RS05365	COG1605	Chorismate mutase
SSCHL_RS05365	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
SSCHL_RS05370	COG1609	Transcriptional regulator
SSCHL_RS05380	COG0454	-acetyltransferase
SSCHL_RS05385	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
SSCHL_RS05390	COG2759	Belongs to the formate--tetrahydrofolate ligase family
SSCHL_RS05395	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SSCHL_RS05405	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SSCHL_RS05410	COG0204	Acyl-transferase
SSCHL_RS05420	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
SSCHL_RS05425	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
SSCHL_RS05430	COG1764	response to oxidative stress
SSCHL_RS05435	COG0584	glycerophosphoryl diester phosphodiesterase
SSCHL_RS05445	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
SSCHL_RS05450	COG1956	GAF domain-containing protein
SSCHL_RS05455	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
SSCHL_RS05460	COG1104	cysteine desulfurase activity
SSCHL_RS05465	COG0301	tRNA thio-modification
SSCHL_RS05475	COG0616	signal peptide processing
SSCHL_RS05485	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
SSCHL_RS05490	COG0827	DNA restriction-modification system
SSCHL_RS05495	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
SSCHL_RS05500	COG0589	response to stress
SSCHL_RS05505	COG0686	Belongs to the AlaDH PNT family
SSCHL_RS05515	COG0006	proline dipeptidase activity
SSCHL_RS05520	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
SSCHL_RS05530	COG4109	DRTGG domain
SSCHL_RS05535	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
SSCHL_RS05545	COG0281	malic enzyme
SSCHL_RS05550	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
SSCHL_RS05555	COG0825	malonyl-CoA metabolic process
SSCHL_RS05560	COG0205	6-phosphofructokinase activity
SSCHL_RS05565	COG0469	pyruvate kinase activity
SSCHL_RS05570	COG0372	Belongs to the citrate synthase family
SSCHL_RS05575	COG0538	isocitrate dehydrogenase activity
SSCHL_RS05580	COG0745	RESPONSE REGULATOR receiver
SSCHL_RS05585	COG5002	protein histidine kinase activity
SSCHL_RS05590	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SSCHL_RS05590	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SSCHL_RS05595	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
SSCHL_RS05600	COG0237	dephospho-CoA kinase activity
SSCHL_RS05605	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
SSCHL_RS05610	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
SSCHL_RS05615	COG3611	Membrane attachment protein
SSCHL_RS05620	COG1484	DNA-dependent DNA replication
SSCHL_RS05630	COG0833	amino acid
SSCHL_RS05635	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
SSCHL_RS05640	COG0291	Belongs to the bacterial ribosomal protein bL35 family
SSCHL_RS05650	COG4112	unkown
SSCHL_RS05660	COG0544	peptidyl-prolyl cis-trans isomerase activity
SSCHL_RS05665	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
SSCHL_RS05670	COG0218	Necessary for normal cell division and for the maintenance of normal septation
SSCHL_RS05675	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
SSCHL_RS05680	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
SSCHL_RS05685	COG0181	hydroxymethylbilane synthase activity
SSCHL_RS05695	COG0113	porphobilinogen synthase activity
SSCHL_RS05700	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
SSCHL_RS05710	COG2818	Glycosylase
SSCHL_RS05715	COG0525	valine-tRNA ligase activity
SSCHL_RS05720	COG0285	dihydrofolate synthase activity
SSCHL_RS05730	COG2003	Belongs to the UPF0758 family
SSCHL_RS05750	COG0261	This protein binds to 23S rRNA in the presence of protein L20
SSCHL_RS05755	COG2868	ribosomal protein
SSCHL_RS05770	COG4492	Belongs to the UPF0735 family
SSCHL_RS05775	COG0632	four-way junction helicase activity
SSCHL_RS05780	COG2255	four-way junction helicase activity
SSCHL_RS05785	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
SSCHL_RS05795	COG1862	Preprotein translocase
SSCHL_RS05800	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
SSCHL_RS05800	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
SSCHL_RS05805	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
SSCHL_RS05805	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
SSCHL_RS05810	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
SSCHL_RS05820	COG1490	D-aminoacyl-tRNA deacylase activity
SSCHL_RS05825	COG0860	N-Acetylmuramoyl-L-alanine amidase
SSCHL_RS05835	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
SSCHL_RS05845	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
SSCHL_RS05850	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
SSCHL_RS05855	COG1959	2 iron, 2 sulfur cluster binding
SSCHL_RS05870	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SSCHL_RS05875	COG1104	cysteine desulfurase activity
SSCHL_RS05880	COG0482	sulfurtransferase activity
SSCHL_RS05890	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
SSCHL_RS05895	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
SSCHL_RS05900	COG4472	Bacterial protein of unknown function (DUF965)
SSCHL_RS05905	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
SSCHL_RS05910	COG3906	Belongs to the UPF0473 family
SSCHL_RS05915	COG4122	O-methyltransferase activity
SSCHL_RS05920	COG0826	peptidase U32
SSCHL_RS05925	COG0826	peptidase U32
SSCHL_RS05930	COG0572	uridine kinase
SSCHL_RS05940	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
SSCHL_RS05945	COG1984	allophanate hydrolase subunit 2
SSCHL_RS05950	COG0511	ligase activity, forming carbon-carbon bonds
SSCHL_RS05955	COG0439	Biotin carboxylase
SSCHL_RS05960	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
SSCHL_RS05965	COG1914	H( )-stimulated, divalent metal cation uptake system
SSCHL_RS05970	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
SSCHL_RS05975	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
SSCHL_RS05980	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
SSCHL_RS05990	COG1534	Rna-binding protein
SSCHL_RS06000	COG1713	HD superfamily hydrolase involved in NAD metabolism
SSCHL_RS06005	COG0799	negative regulation of ribosome biogenesis
SSCHL_RS06010	COG2226	methyltransferase
SSCHL_RS06015	COG1555	photosystem II stabilization
SSCHL_RS06015	COG1596	polysaccharide export
SSCHL_RS06020	COG2131	deaminase
SSCHL_RS06030	COG1466	dna polymerase III delta subunit
SSCHL_RS06035	COG0268	Binds directly to 16S ribosomal RNA
SSCHL_RS06045	COG0635	Involved in the biosynthesis of porphyrin-containing compound
SSCHL_RS06050	COG1420	regulation of RNA biosynthetic process
SSCHL_RS06065	COG0484	heat shock protein binding
SSCHL_RS06070	COG2264	protein methyltransferase activity
SSCHL_RS06075	COG1385	rRNA (uridine-N3-)-methyltransferase activity
SSCHL_RS06080	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
SSCHL_RS06095	COG4864	UPF0365 protein
SSCHL_RS06105	COG1702	phosphate starvation-inducible protein PhoH
SSCHL_RS06110	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
SSCHL_RS06115	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
SSCHL_RS06120	COG0295	cytidine deaminase activity
SSCHL_RS06130	COG1381	Involved in DNA repair and RecF pathway recombination
SSCHL_RS06135	COG0423	glycine-tRNA ligase activity
SSCHL_RS06140	COG0517	IMP dehydrogenase activity
SSCHL_RS06145	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
SSCHL_RS06150	COG0358	DNA primase activity
SSCHL_RS06155	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
SSCHL_RS06160	COG2384	SAM-dependent methyltransferase
SSCHL_RS06170	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
SSCHL_RS06175	COG0513	Belongs to the DEAD box helicase family
SSCHL_RS06180	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
SSCHL_RS06185	COG1121	(ABC) transporter
SSCHL_RS06190	COG1108	ABC-type Mn2 Zn2 transport systems permease components
SSCHL_RS06195	COG0735	belongs to the Fur family
SSCHL_RS06200	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
SSCHL_RS06205	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
SSCHL_RS06210	COG0768	penicillin binding
SSCHL_RS06215	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
SSCHL_RS06220	COG0573	inorganic phosphate transmembrane transporter activity
SSCHL_RS06225	COG0581	inorganic phosphate transmembrane transporter activity
SSCHL_RS06230	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
SSCHL_RS06235	COG0704	Plays a role in the regulation of phosphate uptake
SSCHL_RS06240	COG0267	Belongs to the bacterial ribosomal protein bL33 family
SSCHL_RS06245	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
SSCHL_RS06250	COG0705	Rhomboid family
SSCHL_RS06250	COG0457	Tetratricopeptide repeat
SSCHL_RS06255	COG4483	Protein conserved in bacteria
SSCHL_RS06260	COG1940	carbohydrate kinase activity
SSCHL_RS06265	COG0011	TIGRFAM Protein of
SSCHL_RS06270	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
SSCHL_RS06275	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
SSCHL_RS06280	COG1459	type II secretion system
SSCHL_RS06300	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
SSCHL_RS06305	COG0404	The glycine cleavage system catalyzes the degradation of glycine
SSCHL_RS06315	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
SSCHL_RS06320	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
SSCHL_RS06325	COG0095	Lipoate-protein ligase
SSCHL_RS06340	COG0006	proline dipeptidase activity
SSCHL_RS06345	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
SSCHL_RS06350	COG0511	ligase activity, forming carbon-carbon bonds
SSCHL_RS06355	COG0439	Biotin carboxylase
SSCHL_RS06360	COG1302	Protein conserved in bacteria
SSCHL_RS06380	COG0142	geranyltranstransferase activity
SSCHL_RS06385	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
SSCHL_RS06390	COG1438	arginine binding
SSCHL_RS06395	COG0497	DNA recombination
SSCHL_RS06400	COG0280	phosphate acetyltransferase
SSCHL_RS06405	COG3426	butyrate kinase activity
SSCHL_RS06410	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SSCHL_RS06415	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
SSCHL_RS06420	COG0022	dehydrogenase e1 component
SSCHL_RS06425	COG0508	dehydrogenase complex catalyzes the overall conversion of
SSCHL_RS06435	COG4129	membrane
SSCHL_RS06440	COG2195	Cleaves the N-terminal amino acid of tripeptides
SSCHL_RS06460	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
SSCHL_RS06465	COG1234	tRNA 3'-trailer cleavage
SSCHL_RS06470	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
SSCHL_RS06480	COG0667	Aldo Keto reductase
SSCHL_RS06485	COG0494	nUDIX hydrolase
SSCHL_RS06490	COG0735	belongs to the Fur family
SSCHL_RS06505	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
SSCHL_RS06510	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
SSCHL_RS06515	COG1187	pseudouridine synthase activity
SSCHL_RS06520	COG0745	RESPONSE REGULATOR receiver
SSCHL_RS06525	COG5002	protein histidine kinase activity
SSCHL_RS06535	COG1141	Ferredoxin
SSCHL_RS06545	COG0514	ATP-dependent DNA helicase (RecQ)
SSCHL_RS06555	COG0492	ferredoxin-NADP+ reductase activity
SSCHL_RS06565	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
SSCHL_RS06570	COG0539	negative regulation of cytoplasmic translation
SSCHL_RS06595	COG2226	methyltransferase
SSCHL_RS06600	COG0142	geranyltranstransferase activity
SSCHL_RS06605	COG0105	UTP biosynthetic process
SSCHL_RS06615	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
SSCHL_RS06625	COG0457	Tetratricopeptide repeat
SSCHL_RS06630	COG5582	Belongs to the UPF0302 family
SSCHL_RS06635	COG4347	Protein of unknown function (DUF1405)
SSCHL_RS06640	COG2738	Putative neutral zinc metallopeptidase
SSCHL_RS06650	COG1694	Mazg nucleotide pyrophosphohydrolase
SSCHL_RS06655	COG0438	transferase activity, transferring glycosyl groups
SSCHL_RS06660	COG0617	tRNA 3'-terminal CCA addition
SSCHL_RS06670	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
SSCHL_RS06670	COG1199	ATP-dependent helicase activity
SSCHL_RS06675	COG0017	Asparaginyl-tRNA synthetase
SSCHL_RS06680	COG3935	DnaD domain protein
SSCHL_RS06685	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
SSCHL_RS06695	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SSCHL_RS06695	COG4499	WXG100 protein secretion system (Wss), protein YukC
SSCHL_RS06700	COG3331	DNA recombination
SSCHL_RS06710	COG4474	Belongs to the UPF0398 family
SSCHL_RS06715	COG3599	regulation of cell shape
SSCHL_RS06725	COG0116	Belongs to the methyltransferase superfamily
SSCHL_RS06730	COG2962	Rard protein
SSCHL_RS06735	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
SSCHL_RS06740	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SSCHL_RS06750	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
SSCHL_RS06760	COG1413	lyase activity
SSCHL_RS06795	COG2190	(PTS) system
SSCHL_RS06800	COG4479	Belongs to the UPF0346 family
SSCHL_RS06805	COG0793	Belongs to the peptidase S41A family
SSCHL_RS06815	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
SSCHL_RS06820	COG0671	phosphoesterase, PA-phosphatase related
SSCHL_RS06830	COG5002	protein histidine kinase activity
SSCHL_RS06835	COG0567	Dehydrogenase, E1 component
SSCHL_RS06860	COG0714	Associated with various cellular activities
SSCHL_RS06865	COG4548	von Willebrand factor, type A
SSCHL_RS06870	COG1114	Component of the transport system for branched-chain amino acids
SSCHL_RS06875	COG3853	Toxic anion resistance protein (TelA)
SSCHL_RS06885	COG1254	Belongs to the acylphosphatase family
SSCHL_RS06895	COG1278	Cold shock
SSCHL_RS06910	COG1473	amidohydrolase
SSCHL_RS06915	COG2171	N-acyltransferase activity
SSCHL_RS06920	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
SSCHL_RS06925	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
SSCHL_RS06930	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
SSCHL_RS06935	COG0488	(ABC) transporter
SSCHL_RS06940	COG2996	Protein conserved in bacteria
SSCHL_RS06945	COG3711	transcriptional antiterminator
SSCHL_RS06950	COG1447	Phosphotransferase system cellobiose-specific component IIA
SSCHL_RS06955	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
SSCHL_RS06955	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
SSCHL_RS06960	COG2723	6-phospho-beta-galactosidase activity
SSCHL_RS06970	COG0698	ribose 5-phosphate isomerase
SSCHL_RS06975	COG0698	ribose 5-phosphate isomerase
SSCHL_RS07005	COG1363	Peptidase, m42
SSCHL_RS07010	COG0287	Prephenate dehydrogenase
SSCHL_RS07015	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
SSCHL_RS07045	COG0628	permease
SSCHL_RS07055	COG3711	transcriptional antiterminator
SSCHL_RS07060	COG1115	amino acid carrier protein
SSCHL_RS07065	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
SSCHL_RS07070	COG0187	DNA topoisomerase II activity
SSCHL_RS07075	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
SSCHL_RS07080	COG4841	protein insertion into membrane
SSCHL_RS07085	COG0824	Thioesterase
SSCHL_RS07090	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
SSCHL_RS07095	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
SSCHL_RS07100	COG1970	mechanosensitive ion channel activity
SSCHL_RS07115	COG4846	Membrane protein involved in cytochrome C biogenesis
SSCHL_RS07125	COG3763	UPF0154 protein
SSCHL_RS07135	COG4224	UPF0291 protein
SSCHL_RS07145	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
SSCHL_RS07155	COG0516	GMP reductase activity
SSCHL_RS07170	COG0833	amino acid
SSCHL_RS07180	COG0561	phosphatase activity
SSCHL_RS07185	COG0083	homoserine kinase activity
SSCHL_RS07190	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
SSCHL_RS07195	COG0460	homoserine dehydrogenase
SSCHL_RS07200	COG0527	aspartate kinase activity
SSCHL_RS07230	COG1518	maintenance of DNA repeat elements
SSCHL_RS07245	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
SSCHL_RS07250	COG1525	nuclease
SSCHL_RS07270	COG1525	nuclease
SSCHL_RS07280	COG0584	glycerophosphoryl diester phosphodiesterase
SSCHL_RS07305	COG0789	Transcriptional regulator
SSCHL_RS07310	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
SSCHL_RS07315	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
SSCHL_RS07320	COG0386	Belongs to the glutathione peroxidase family
SSCHL_RS07325	COG1923	regulation of RNA biosynthetic process
SSCHL_RS07330	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
SSCHL_RS07335	COG2267	carboxylic ester hydrolase activity
SSCHL_RS07340	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
SSCHL_RS07350	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
SSCHL_RS07360	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
SSCHL_RS07365	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
SSCHL_RS07370	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
SSCHL_RS07385	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
SSCHL_RS07395	COG1013	pyruvate-flavodoxin oxidoreductase activity
SSCHL_RS07400	COG0674	pyruvate-flavodoxin oxidoreductase activity
SSCHL_RS07400	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
SSCHL_RS07405	COG1692	metallophosphoesterase
SSCHL_RS07430	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
SSCHL_RS07435	COG1058	Belongs to the CinA family
SSCHL_RS07435	COG1546	Belongs to the CinA family
SSCHL_RS07455	COG1028	Short-chain dehydrogenase reductase Sdr
SSCHL_RS07460	COG0612	Peptidase, M16
SSCHL_RS07465	COG0612	Peptidase, M16
SSCHL_RS07470	COG2188	Transcriptional regulator
SSCHL_RS07485	COG1185	polyribonucleotide nucleotidyltransferase activity
SSCHL_RS07495	COG0196	riboflavin kinase activity
SSCHL_RS07500	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
SSCHL_RS07505	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
SSCHL_RS07510	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SSCHL_RS07520	COG1131	(ABC) transporter
SSCHL_RS07525	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
SSCHL_RS07560	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
SSCHL_RS07565	COG1358	cellular component organization or biogenesis
SSCHL_RS07570	COG2740	Nucleic-acid-binding protein implicated in transcription termination
SSCHL_RS07575	COG0195	Participates in both transcription termination and antitermination
SSCHL_RS07580	COG0779	Required for maturation of 30S ribosomal subunits
SSCHL_RS07590	COG0442	prolyl-tRNA aminoacylation
SSCHL_RS07600	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
SSCHL_RS07605	COG4589	Belongs to the CDS family
SSCHL_RS07615	COG0233	cytoplasmic translational termination
SSCHL_RS07620	COG0528	UMP kinase activity
SSCHL_RS07625	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
SSCHL_RS07630	COG0052	Belongs to the universal ribosomal protein uS2 family
SSCHL_RS07635	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
SSCHL_RS07640	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
SSCHL_RS07645	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
SSCHL_RS07650	COG4974	Belongs to the 'phage' integrase family
SSCHL_RS07655	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
SSCHL_RS07660	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
SSCHL_RS07665	COG0758	DNA mediated transformation
SSCHL_RS07675	COG0045	succinate-CoA ligase (ADP-forming) activity
SSCHL_RS07690	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
SSCHL_RS07705	COG4485	Bacterial membrane protein, YfhO
SSCHL_RS07720	COG0336	Belongs to the RNA methyltransferase TrmD family
SSCHL_RS07730	COG0228	four-way junction DNA binding
SSCHL_RS07735	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
SSCHL_RS07740	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
SSCHL_RS07745	COG0552	protein localization to endoplasmic reticulum
SSCHL_RS07750	COG1196	nuclear chromosome segregation
SSCHL_RS07760	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SSCHL_RS07775	COG0416	fatty acid biosynthetic process
SSCHL_RS07780	COG1349	DNA-binding transcription factor activity
SSCHL_RS07790	COG1760	l-serine dehydratase
SSCHL_RS07795	COG1760	l-serine dehydratase
SSCHL_RS07800	COG1461	Dihydroxyacetone kinase
SSCHL_RS07805	COG1302	Protein conserved in bacteria
SSCHL_RS07810	COG0227	Belongs to the bacterial ribosomal protein bL28 family
SSCHL_RS07820	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
SSCHL_RS07825	COG1162	GTPase activity
SSCHL_RS07845	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
SSCHL_RS07845	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
SSCHL_RS07850	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
SSCHL_RS07855	COG0242	peptide deformylase activity
SSCHL_RS07865	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
SSCHL_RS07870	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
SSCHL_RS07875	COG1758	RNA polymerase activity
SSCHL_RS07905	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
SSCHL_RS07910	COG0284	orotidine-5'-phosphate decarboxylase activity
SSCHL_RS07915	COG0167	dihydroorotate dehydrogenase activity
SSCHL_RS07925	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
SSCHL_RS07930	COG0505	Belongs to the CarA family
SSCHL_RS07950	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
SSCHL_RS07955	COG0564	pseudouridine synthase activity
SSCHL_RS07965	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
SSCHL_RS07970	COG3599	regulation of cell shape
SSCHL_RS07980	COG0762	integral membrane protein
SSCHL_RS07985	COG1799	cell septum assembly
SSCHL_RS07990	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
SSCHL_RS07995	COG1496	oxidoreductase activity
SSCHL_RS08000	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
SSCHL_RS08005	COG0849	cell division
SSCHL_RS08015	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
SSCHL_RS08020	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
SSCHL_RS08025	COG0768	penicillin binding
SSCHL_RS08030	COG4839	cell division protein FtsL
SSCHL_RS08035	COG0275	rRNA processing
SSCHL_RS08040	COG2001	Belongs to the MraZ family
SSCHL_RS08045	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
SSCHL_RS08050	COG0454	-acetyltransferase
SSCHL_RS08055	COG1011	Hydrolase
SSCHL_RS08065	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
SSCHL_RS08100	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
SSCHL_RS08105	COG1053	succinate dehydrogenase
SSCHL_RS08110	COG2009	succinate dehydrogenase
SSCHL_RS08115	COG0322	excinuclease ABC activity
SSCHL_RS08120	COG3118	belongs to the thioredoxin family
SSCHL_RS08125	COG1193	negative regulation of DNA recombination
SSCHL_RS08130	COG1796	DNA polymerase
SSCHL_RS08130	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
SSCHL_RS08140	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
SSCHL_RS08145	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
SSCHL_RS08155	COG0072	phenylalanine-tRNA ligase activity
SSCHL_RS08155	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SSCHL_RS08160	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
SSCHL_RS08165	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
SSCHL_RS08170	COG0333	Belongs to the bacterial ribosomal protein bL32 family
SSCHL_RS08185	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
SSCHL_RS08190	COG0742	ribosomal rna small subunit methyltransferase
SSCHL_RS08205	COG0584	glycerophosphoryl diester phosphodiesterase
SSCHL_RS08210	COG3679	Belongs to the UPF0342 family
SSCHL_RS08225	COG0109	protoheme IX farnesyltransferase activity
SSCHL_RS08230	COG1612	heme a metabolic process
SSCHL_RS08240	COG0772	Belongs to the SEDS family
SSCHL_RS08245	COG4838	Belongs to the UPF0358 family
SSCHL_RS08250	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
SSCHL_RS08255	COG4896	Protein conserved in bacteria
SSCHL_RS08260	COG1902	pentaerythritol trinitrate reductase activity
SSCHL_RS08265	COG1217	gtp-binding protein TYPA
SSCHL_RS08275	COG0483	inositol monophosphate 1-phosphatase activity
SSCHL_RS08295	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
SSCHL_RS08300	COG1177	transmembrane transport
SSCHL_RS08310	COG3842	ATPase activity
SSCHL_RS08320	COG4476	Belongs to the UPF0223 family
SSCHL_RS08350	COG0242	peptide deformylase activity
SSCHL_RS08360	COG5503	Protein of unknown function (DUF1447)
SSCHL_RS08365	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
SSCHL_RS08370	COG0569	domain protein
SSCHL_RS08375	COG1294	oxidase, subunit
SSCHL_RS08380	COG1271	oxidase subunit
SSCHL_RS08390	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
SSCHL_RS08395	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
SSCHL_RS08405	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
SSCHL_RS08420	COG1122	ATPase activity
SSCHL_RS08430	COG0151	Belongs to the GarS family
SSCHL_RS08435	COG0138	bifunctional purine biosynthesis protein purh
SSCHL_RS08445	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
SSCHL_RS08450	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
SSCHL_RS08455	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
SSCHL_RS08460	COG0047	phosphoribosylformylglycinamidine synthase activity
SSCHL_RS08465	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
SSCHL_RS08470	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
SSCHL_RS08475	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
SSCHL_RS08480	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
SSCHL_RS08485	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
SSCHL_RS08490	COG0438	transferase activity, transferring glycosyl groups
SSCHL_RS08505	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
SSCHL_RS08515	COG1845	cytochrome c oxidase, subunit III
SSCHL_RS08520	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
SSCHL_RS08530	COG3212	peptidase
SSCHL_RS08540	COG1134	teichoic acid transport
SSCHL_RS08560	COG0438	transferase activity, transferring glycosyl groups
SSCHL_RS08565	COG1215	transferase activity, transferring glycosyl groups
SSCHL_RS08580	COG1682	transport, permease protein
SSCHL_RS08585	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
SSCHL_RS08595	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
SSCHL_RS08600	COG1316	TRANSCRIPTIONal
SSCHL_RS08625	COG3594	Acyltransferase
SSCHL_RS08630	COG0436	Aminotransferase
SSCHL_RS08635	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
SSCHL_RS08640	COG2267	carboxylic ester hydrolase activity
SSCHL_RS08645	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
SSCHL_RS08650	COG1169	isochorismate synthase
SSCHL_RS08655	COG1575	Belongs to the MenA family. Type 1 subfamily
SSCHL_RS08660	COG0390	transport system, permease component
SSCHL_RS08665	COG4619	ABC transporter
SSCHL_RS08700	COG0582	viral genome integration into host DNA
SSCHL_RS08715	COG4903	ComK protein
SSCHL_RS08730	COG4873	Protein conserved in bacteria
SSCHL_RS08740	COG4932	domain protein
SSCHL_RS08740	COG3266	domain, Protein
SSCHL_RS08740	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
SSCHL_RS08745	COG0737	Belongs to the 5'-nucleotidase family
SSCHL_RS08755	COG1696	Membrane protein involved in D-alanine export
SSCHL_RS08765	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
SSCHL_RS08770	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
SSCHL_RS08775	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SSCHL_RS08780	COG0861	Integral membrane protein TerC family
SSCHL_RS08795	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
SSCHL_RS08800	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
SSCHL_RS08805	COG2814	Major facilitator Superfamily
SSCHL_RS08810	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
SSCHL_RS08815	COG2382	esterase
SSCHL_RS08820	COG1115	amino acid carrier protein
SSCHL_RS08825	COG0628	permease
SSCHL_RS08840	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
SSCHL_RS08845	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
SSCHL_RS08855	COG0475	glutathione-regulated potassium exporter activity
SSCHL_RS08855	COG0569	domain protein
SSCHL_RS08860	COG2239	Acts as a magnesium transporter
SSCHL_RS08865	COG0564	pseudouridine synthase activity
SSCHL_RS08870	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
SSCHL_RS08875	COG2357	RelA SpoT domain protein
SSCHL_RS08885	COG4116	CYTH
SSCHL_RS08890	COG2346	COG2346, Truncated hemoglobins
SSCHL_RS08900	COG1164	Oligoendopeptidase f
SSCHL_RS08905	COG4469	Competence protein
SSCHL_RS08910	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
SSCHL_RS08915	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
SSCHL_RS08925	COG1393	Belongs to the ArsC family
SSCHL_RS08930	COG0180	Tryptophanyl-tRNA synthetase
SSCHL_RS08935	COG4166	transmembrane transport
SSCHL_RS08940	COG4608	Belongs to the ABC transporter superfamily
SSCHL_RS08945	COG0444	Belongs to the ABC transporter superfamily
SSCHL_RS08950	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SSCHL_RS08955	COG0601	transmembrane transport
SSCHL_RS08980	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
SSCHL_RS08985	COG0542	response to heat
SSCHL_RS09000	COG0561	phosphatase activity
SSCHL_RS09005	COG0446	pyridine nucleotide-disulphide oxidoreductase
SSCHL_RS09015	COG0179	Fumarylacetoacetate (FAA) hydrolase
SSCHL_RS09020	COG1074	ATP-dependent DNA helicase activity
SSCHL_RS09025	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
SSCHL_RS09045	COG0137	argininosuccinate synthase activity
SSCHL_RS09050	COG0165	Argininosuccinate lyase
SSCHL_RS09055	COG0584	glycerophosphoryl diester phosphodiesterase
SSCHL_RS09070	COG1012	belongs to the aldehyde dehydrogenase family
SSCHL_RS09075	COG1098	S1 RNA binding domain
SSCHL_RS09080	COG1278	Cold shock
SSCHL_RS09100	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
SSCHL_RS09110	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
SSCHL_RS09110	COG2111	Na H antiporter
SSCHL_RS09115	COG2111	Na H antiporter
SSCHL_RS09120	COG1006	Multisubunit Na H antiporter MnhC subunit
SSCHL_RS09125	COG0651	ATP synthesis coupled electron transport
SSCHL_RS09130	COG1863	multisubunit Na H antiporter MnhE subunit
SSCHL_RS09135	COG2212	antiporter activity
SSCHL_RS09140	COG1320	monovalent cation:proton antiporter activity
SSCHL_RS09150	COG2056	Na+-H+ antiporter family
SSCHL_RS09155	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
SSCHL_RS09160	COG1252	NADH dehydrogenase
SSCHL_RS09170	COG0316	Belongs to the HesB IscA family
SSCHL_RS09175	COG4844	belongs to the
SSCHL_RS09180	COG1252	NADH dehydrogenase
SSCHL_RS09185	COG4837	Protein of unknown function (DUF1462)
SSCHL_RS09190	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
SSCHL_RS09195	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
SSCHL_RS09200	COG0647	UMP catabolic process
SSCHL_RS09205	COG2445	Protein of unknown function DUF86
SSCHL_RS09215	COG4470	Protein conserved in bacteria
SSCHL_RS09220	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
SSCHL_RS09225	COG0737	Belongs to the 5'-nucleotidase family
SSCHL_RS09230	COG0730	response to heat
SSCHL_RS09235	COG1801	Protein of unknown function DUF72
SSCHL_RS09245	COG2070	2-Nitropropane dioxygenase
SSCHL_RS09250	COG4536	flavin adenine dinucleotide binding
SSCHL_RS09475	COG1484	DNA-dependent DNA replication
SSCHL_RS09545	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
SSCHL_RS09575	COG0719	Fe-S assembly protein
SSCHL_RS09580	COG0822	iron-sulfur transferase activity
SSCHL_RS09590	COG0719	Fe-S assembly protein
SSCHL_RS09595	COG0396	ATPase activity
SSCHL_RS09605	COG1464	Belongs to the NlpA lipoprotein family
SSCHL_RS09610	COG1464	Belongs to the NlpA lipoprotein family
SSCHL_RS09615	COG2011	ABC-type metal ion transport system permease component
SSCHL_RS09620	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
SSCHL_RS09625	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
SSCHL_RS09630	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
SSCHL_RS09640	COG1393	Belongs to the ArsC family
SSCHL_RS09645	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
SSCHL_RS09655	COG0710	3-dehydroquinate dehydratase activity
SSCHL_RS09665	COG1764	response to oxidative stress
SSCHL_RS09675	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
SSCHL_RS09710	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
SSCHL_RS09715	COG0557	exoribonuclease II activity
SSCHL_RS09720	COG1647	Serine aminopeptidase, S33
SSCHL_RS09725	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
SSCHL_RS09740	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
SSCHL_RS09745	COG0149	triose-phosphate isomerase activity
SSCHL_RS09750	COG0126	phosphoglycerate kinase activity
SSCHL_RS09755	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
SSCHL_RS09775	COG1090	epimerase
SSCHL_RS09785	COG0740	serine-type endopeptidase activity
SSCHL_RS09795	COG1481	regulation of sporulation
SSCHL_RS09800	COG0391	Required for morphogenesis under gluconeogenic growth conditions
SSCHL_RS09805	COG1660	Displays ATPase and GTPase activities
SSCHL_RS09810	COG0492	ferredoxin-NADP+ reductase activity
SSCHL_RS09820	COG0110	maltose O-acetyltransferase activity
SSCHL_RS09830	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
SSCHL_RS09860	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
SSCHL_RS09865	COG0653	protein targeting
SSCHL_RS09880	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
SSCHL_RS09890	COG1739	Uncharacterized protein family UPF0029
SSCHL_RS09895	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
SSCHL_RS09915	COG2195	Cleaves the N-terminal amino acid of tripeptides
SSCHL_RS09920	COG1929	Belongs to the glycerate kinase type-1 family
SSCHL_RS09940	COG0812	UDP-N-acetylmuramate dehydrogenase activity
SSCHL_RS09950	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
SSCHL_RS09955	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
SSCHL_RS09970	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
SSCHL_RS09975	COG3104	oligopeptide transport
SSCHL_RS09980	COG3104	oligopeptide transport
SSCHL_RS09995	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
SSCHL_RS10000	COG1174	glycine betaine transport
SSCHL_RS10005	COG0517	IMP dehydrogenase activity
SSCHL_RS10005	COG1125	glycine betaine transport
SSCHL_RS10010	COG0514	ATP-dependent DNA helicase (RecQ)
SSCHL_RS10015	COG0488	(ABC) transporter
SSCHL_RS10025	COG1368	sulfuric ester hydrolase activity
SSCHL_RS10030	COG1984	allophanate hydrolase subunit 2
SSCHL_RS10035	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
SSCHL_RS10055	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
SSCHL_RS10055	COG0512	Glutamine amidotransferase of anthranilate synthase
SSCHL_RS10065	COG0720	synthase
SSCHL_RS10080	COG2261	transglycosylase associated protein
SSCHL_RS10090	COG0463	Glycosyl transferase, family 2
SSCHL_RS10095	COG1253	flavin adenine dinucleotide binding
SSCHL_RS10105	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SSCHL_RS10105	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SSCHL_RS10105	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SSCHL_RS10110	COG1105	Belongs to the carbohydrate kinase PfkB family
SSCHL_RS10115	COG1349	DNA-binding transcription factor activity
SSCHL_RS10120	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
SSCHL_RS10125	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
SSCHL_RS10150	COG0039	L-malate dehydrogenase activity
SSCHL_RS10160	COG4989	oxidoreductase activity
SSCHL_RS10175	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
SSCHL_RS10180	COG4988	ABC transporter
SSCHL_RS10185	COG1968	undecaprenyl-diphosphatase activity
SSCHL_RS10195	COG1671	Belongs to the UPF0178 family
SSCHL_RS10200	COG1611	Belongs to the LOG family
SSCHL_RS10230	COG2814	Major facilitator Superfamily
SSCHL_RS10235	COG0583	DNA-binding transcription factor activity
SSCHL_RS10250	COG0217	transcriptional regulatory protein
SSCHL_RS10260	COG2022	thiamine diphosphate biosynthetic process
SSCHL_RS10265	COG2104	thiamine diphosphate biosynthetic process
SSCHL_RS10265	COG2022	thiamine diphosphate biosynthetic process
SSCHL_RS10270	COG0352	thiamine-phosphate diphosphorylase activity
SSCHL_RS10285	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
SSCHL_RS10295	COG2205	protein histidine kinase activity
SSCHL_RS10300	COG0745	RESPONSE REGULATOR receiver
SSCHL_RS10310	COG2130	NADP-dependent
SSCHL_RS10315	COG0702	epimerase
SSCHL_RS10335	COG2348	transferase activity, transferring amino-acyl groups
SSCHL_RS10340	COG3942	CHAP domain
SSCHL_RS10340	COG1388	LysM domain
SSCHL_RS10350	COG0306	phosphate transporter
SSCHL_RS10355	COG1392	Phosphate transport regulator
SSCHL_RS10360	COG0577	efflux transmembrane transporter activity
SSCHL_RS10365	COG1136	(ABC) transporter
SSCHL_RS10375	COG0745	RESPONSE REGULATOR receiver
SSCHL_RS10380	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
SSCHL_RS10390	COG0657	acetylesterase activity
SSCHL_RS10395	COG3949	Membrane
SSCHL_RS10405	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SSCHL_RS10410	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SSCHL_RS10415	COG1120	ATPase activity
SSCHL_RS10420	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
SSCHL_RS10425	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
SSCHL_RS10440	COG1132	(ABC) transporter
SSCHL_RS10445	COG1686	Belongs to the peptidase S11 family
SSCHL_RS10450	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
SSCHL_RS10455	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
SSCHL_RS10460	COG1682	transport, permease protein
SSCHL_RS10465	COG1134	teichoic acid transport
SSCHL_RS10470	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
SSCHL_RS10485	COG1121	(ABC) transporter
SSCHL_RS10490	COG1108	ABC-type Mn2 Zn2 transport systems permease components
SSCHL_RS10495	COG0803	Belongs to the bacterial solute-binding protein 9 family
SSCHL_RS10500	COG1320	monovalent cation:proton antiporter activity
SSCHL_RS10505	COG2212	antiporter activity
SSCHL_RS10510	COG1863	multisubunit Na H antiporter MnhE subunit
SSCHL_RS10520	COG1006	Multisubunit Na H antiporter MnhC subunit
SSCHL_RS10525	COG2111	Na H antiporter
SSCHL_RS10530	COG2111	Na H antiporter
SSCHL_RS10530	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
SSCHL_RS10535	COG0582	viral genome integration into host DNA
SSCHL_RS10580	COG0596	Alpha beta hydrolase
SSCHL_RS10590	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SSCHL_RS10595	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
SSCHL_RS10600	COG0018	arginyl-trna synthetase
SSCHL_RS10615	COG1078	dGTPase activity
SSCHL_RS10625	COG0655	NAD(P)H dehydrogenase (quinone) activity
SSCHL_RS10630	COG4844	belongs to the
SSCHL_RS10635	COG0095	Lipoate-protein ligase
SSCHL_RS10660	COG0471	metal ion transport
SSCHL_RS10665	COG2814	Major facilitator Superfamily
SSCHL_RS10670	COG1566	PFAM secretion protein HlyD family protein
SSCHL_RS10680	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
SSCHL_RS10690	COG2363	Small membrane protein
SSCHL_RS10720	COG0183	Belongs to the thiolase family
SSCHL_RS10725	COG0318	PFAM AMP-dependent synthetase and ligase
SSCHL_RS10730	COG0588	phosphoglycerate mutase activity
SSCHL_RS10735	COG1609	Transcriptional regulator
SSCHL_RS10740	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
SSCHL_RS10745	COG0561	phosphatase activity
SSCHL_RS10750	COG0673	inositol 2-dehydrogenase activity
SSCHL_RS10760	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
SSCHL_RS10770	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
SSCHL_RS10775	COG0363	glucosamine-6-phosphate deaminase activity
SSCHL_RS10795	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
SSCHL_RS10805	COG0561	phosphatase activity
SSCHL_RS10815	COG1428	Deoxynucleoside kinase
SSCHL_RS10820	COG1428	Deoxynucleoside kinase
SSCHL_RS10825	COG0546	phosphoglycolate phosphatase activity
SSCHL_RS10835	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
SSCHL_RS10845	COG1473	amidohydrolase
SSCHL_RS10850	COG0028	Belongs to the TPP enzyme family
SSCHL_RS10855	COG3527	Alpha-acetolactate decarboxylase
SSCHL_RS10865	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
SSCHL_RS10870	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
SSCHL_RS10875	COG0049	tRNA binding
SSCHL_RS10880	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
SSCHL_RS10890	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
SSCHL_RS10895	COG0085	RNA polymerase activity
SSCHL_RS10900	COG2813	Specifically methylates the guanine in position
SSCHL_RS10910	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
SSCHL_RS10915	COG0081	regulation of translation
SSCHL_RS10920	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
SSCHL_RS10925	COG0250	Participates in transcription elongation, termination and antitermination
SSCHL_RS10930	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
SSCHL_RS10950	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
SSCHL_RS10955	COG0215	cysteine-tRNA ligase activity
SSCHL_RS10965	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
SSCHL_RS10970	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
SSCHL_RS10980	COG4956	integral membrane protein (PIN domain superfamily)
SSCHL_RS10985	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
SSCHL_RS10995	COG3869	Catalyzes the specific phosphorylation of arginine residues in
SSCHL_RS11000	COG3880	PFAM UvrB UvrC protein
SSCHL_RS11005	COG4463	regulation of RNA biosynthetic process
SSCHL_RS11010	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
SSCHL_RS11015	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
SSCHL_RS11020	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
SSCHL_RS11025	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SSCHL_RS11030	COG1289	transmembrane transporter activity
SSCHL_RS11100	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
SSCHL_RS11110	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
SSCHL_RS11120	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
SSCHL_RS11125	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
SSCHL_RS11140	COG1098	S1 RNA binding domain
SSCHL_RS11150	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
SSCHL_RS11155	COG3956	TIGRFAM MazG family protein
SSCHL_RS11160	COG2244	polysaccharide biosynthetic process
SSCHL_RS11165	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
SSCHL_RS11170	COG0193	aminoacyl-tRNA hydrolase activity
SSCHL_RS11180	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
SSCHL_RS11185	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
SSCHL_RS11195	COG2088	sporulation resulting in formation of a cellular spore
SSCHL_RS11200	COG0251	oxidation-reduction process
SSCHL_RS11205	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
SSCHL_RS11210	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
SSCHL_RS11215	COG4466	Protein conserved in bacteria
SSCHL_RS11225	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
SSCHL_RS11230	COG0084	hydrolase, TatD family'
SSCHL_RS11240	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
SSCHL_RS11245	COG2827	Endonuclease containing a URI domain
SSCHL_RS11250	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
SSCHL_RS11260	COG1774	PSP1 C-terminal conserved region
SSCHL_RS11270	COG3870	Protein conserved in bacteria
SSCHL_RS11275	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
SSCHL_RS11280	COG1982	Orn Lys Arg decarboxylase major
SSCHL_RS11305	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
SSCHL_RS11310	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
SSCHL_RS11315	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
SSCHL_RS11335	COG0493	'glutamate synthase
SSCHL_RS11340	COG0067	glutamate synthase
SSCHL_RS11340	COG0069	glutamate synthase activity
SSCHL_RS11340	COG0070	glutamate synthase
SSCHL_RS11360	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
SSCHL_RS11375	COG1309	transcriptional regulator
SSCHL_RS11380	COG1511	domain protein
SSCHL_RS11390	COG0626	cystathionine gamma-synthase activity
SSCHL_RS11395	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
SSCHL_RS11405	COG2272	Belongs to the type-B carboxylesterase lipase family
SSCHL_RS11410	COG0733	neurotransmitter:sodium symporter activity
SSCHL_RS11420	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
SSCHL_RS11425	COG0574	Belongs to the PEP-utilizing enzyme family
SSCHL_RS11425	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
SSCHL_RS11440	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
SSCHL_RS11475	COG0456	acetyltransferase
SSCHL_RS11490	COG1124	(ABC) transporter
SSCHL_RS11495	COG0444	Belongs to the ABC transporter superfamily
SSCHL_RS11500	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SSCHL_RS11505	COG0601	transmembrane transport
SSCHL_RS11540	COG3189	MarR family transcriptional regulator
SSCHL_RS11545	COG2814	Major facilitator Superfamily
SSCHL_RS11565	COG1683	Conserved Protein
SSCHL_RS11570	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
SSCHL_RS11575	COG1136	(ABC) transporter
SSCHL_RS11575	COG0577	efflux transmembrane transporter activity
SSCHL_RS11645	COG0518	GMP synthase (glutamine-hydrolyzing) activity
SSCHL_RS11645	COG0519	Catalyzes the synthesis of GMP from XMP
SSCHL_RS11650	COG0516	GMP reductase activity
SSCHL_RS11650	COG0517	IMP dehydrogenase activity
SSCHL_RS11655	COG2233	PERMEase
SSCHL_RS11660	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
SSCHL_RS11675	COG5183	chlorophyll binding
SSCHL_RS11680	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SSCHL_RS11685	COG1823	symporter activity
SSCHL_RS11690	COG0778	Nitroreductase
SSCHL_RS11695	COG0450	alkyl hydroperoxide reductase
SSCHL_RS11705	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
SSCHL_RS11710	COG5646	InterPro IPR014922
SSCHL_RS11715	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
SSCHL_RS11720	COG2011	ABC-type metal ion transport system permease component
SSCHL_RS11725	COG1464	Belongs to the NlpA lipoprotein family
SSCHL_RS11730	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
SSCHL_RS11735	COG2814	Major facilitator Superfamily
SSCHL_RS11745	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
SSCHL_RS11755	COG0360	Binds together with S18 to 16S ribosomal RNA
SSCHL_RS11775	COG0012	GTP binding
SSCHL_RS11780	COG4481	Protein conserved in bacteria
SSCHL_RS11785	COG0668	transmembrane transport
SSCHL_RS11790	COG1475	DNA binding
SSCHL_RS11795	COG0626	cystathionine gamma-synthase activity
SSCHL_RS11800	COG0626	cystathionine gamma-synthase activity
SSCHL_RS11805	COG0646	methionine synthase
SSCHL_RS11805	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
SSCHL_RS11820	COG0829	nickel cation binding
SSCHL_RS11830	COG0830	nickel cation binding
SSCHL_RS11835	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
SSCHL_RS11840	COG2353	YceI-like domain
SSCHL_RS11845	COG1846	Transcriptional regulator
SSCHL_RS11855	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
SSCHL_RS11860	COG0400	carboxylic ester hydrolase activity
SSCHL_RS11895	COG1475	DNA binding
SSCHL_RS11900	COG0357	Ribosomal RNA small subunit methyltransferase G
SSCHL_RS11905	COG0445	tRNA wobble uridine modification
SSCHL_RS11910	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
SSCHL_RS11915	COG0594	ribonuclease P activity