locus-tag	class	description
CEP64_RS00010	COG0157	Belongs to the NadC ModD family
CEP64_RS00015	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
CEP64_RS00020	COG1104	cysteine desulfurase activity
CEP64_RS00025	COG1827	regulation of RNA biosynthetic process
CEP64_RS00035	COG2318	DinB family
CEP64_RS00040	COG2851	Citrate transporter
CEP64_RS00055	COG1054	Belongs to the UPF0176 family
CEP64_RS00100	COG0083	homoserine kinase activity
CEP64_RS00105	COG3386	PFAM SMP-30 Gluconolaconase
CEP64_RS00110	COG1304	FMN binding
CEP64_RS00130	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CEP64_RS00135	COG1028	Short-chain dehydrogenase reductase Sdr
CEP64_RS00145	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CEP64_RS00145	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CEP64_RS00145	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CEP64_RS00150	COG3711	transcriptional antiterminator
CEP64_RS00150	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CEP64_RS00160	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CEP64_RS00175	COG0579	oxidoreductase
CEP64_RS00185	COG0318	PFAM AMP-dependent synthetase and ligase
CEP64_RS00190	COG1960	acyl-CoA dehydrogenase activity
CEP64_RS00195	COG1024	Enoyl-CoA hydratase
CEP64_RS00195	COG1250	3-hydroxyacyl-CoA dehydrogenase
CEP64_RS00200	COG0183	Belongs to the thiolase family
CEP64_RS00205	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CEP64_RS00210	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CEP64_RS00215	COG3002	Belongs to the UPF0753 family
CEP64_RS00220	COG0288	reversible hydration of carbon dioxide
CEP64_RS00225	COG5609	conserved protein (DUF2294)
CEP64_RS00230	COG1283	sodium-dependent phosphate transmembrane transporter activity
CEP64_RS00235	COG0673	inositol 2-dehydrogenase activity
CEP64_RS00245	COG0673	inositol 2-dehydrogenase activity
CEP64_RS00265	COG2226	methyltransferase
CEP64_RS00270	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
CEP64_RS00285	COG0733	neurotransmitter:sodium symporter activity
CEP64_RS00290	COG0583	DNA-binding transcription factor activity
CEP64_RS00295	COG1380	Effector of murein hydrolase LrgA
CEP64_RS00300	COG1346	cytolysis
CEP64_RS00310	COG0175	sulfate reduction
CEP64_RS00315	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
CEP64_RS00320	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CEP64_RS00340	COG0730	response to heat
CEP64_RS00345	COG2046	Belongs to the sulfate adenylyltransferase family
CEP64_RS00350	COG0529	Catalyzes the synthesis of activated sulfate
CEP64_RS00355	COG1510	regulation of RNA biosynthetic process
CEP64_RS00360	COG1012	belongs to the aldehyde dehydrogenase family
CEP64_RS00365	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
CEP64_RS00375	COG0659	secondary active sulfate transmembrane transporter activity
CEP64_RS00385	COG1621	beta-fructofuranosidase activity
CEP64_RS00405	COG1247	-acetyltransferase
CEP64_RS00415	COG0668	transmembrane transport
CEP64_RS00420	COG2851	Citrate transporter
CEP64_RS00425	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CEP64_RS00445	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CEP64_RS00450	COG1113	amino acid transport
CEP64_RS00455	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
CEP64_RS00460	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CEP64_RS00465	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CEP64_RS00475	COG0477	Major facilitator Superfamily
CEP64_RS00480	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CEP64_RS00500	COG2205	protein histidine kinase activity
CEP64_RS00505	COG0745	RESPONSE REGULATOR receiver
CEP64_RS00510	COG2311	Membrane
CEP64_RS00525	COG3961	Belongs to the TPP enzyme family
CEP64_RS00545	COG1063	alcohol dehydrogenase
CEP64_RS00555	COG1063	alcohol dehydrogenase
CEP64_RS00560	COG3775	system Galactitol-specific IIC component
CEP64_RS00565	COG3414	Phosphotransferase system galactitol-specific IIB component
CEP64_RS00580	COG0531	amino acid
CEP64_RS00590	COG1464	Belongs to the NlpA lipoprotein family
CEP64_RS00595	COG2271	Major facilitator Superfamily
CEP64_RS00620	COG0531	amino acid
CEP64_RS00625	COG2130	NADP-dependent
CEP64_RS00640	COG2188	Transcriptional regulator
CEP64_RS00645	COG2222	sugar isomerase
CEP64_RS00650	COG1105	Belongs to the carbohydrate kinase PfkB family
CEP64_RS00655	COG3684	Belongs to the aldolase LacD family
CEP64_RS00665	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CEP64_RS00670	COG3715	PTS system
CEP64_RS00675	COG3716	PTS system mannose fructose sorbose family IID component
CEP64_RS00695	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
CEP64_RS00705	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
CEP64_RS00725	COG1316	TRANSCRIPTIONal
CEP64_RS00735	COG3001	Fructosamine kinase
CEP64_RS00740	COG0662	Cupin 2, conserved barrel domain protein
CEP64_RS00745	COG2807	transmembrane transport
CEP64_RS00750	COG1113	amino acid transport
CEP64_RS00760	COG3620	sequence-specific DNA binding
CEP64_RS00780	COG0488	(ABC) transporter
CEP64_RS00800	COG2084	Dehydrogenase
CEP64_RS00810	COG2610	gluconate transmembrane transporter activity
CEP64_RS00825	COG4336	lyase activity
CEP64_RS00830	COG3275	phosphorelay sensor kinase activity
CEP64_RS00835	COG3279	Response regulator of the LytR AlgR family
CEP64_RS00840	COG1380	Effector of murein hydrolase LrgA
CEP64_RS00845	COG1346	cytolysis
CEP64_RS00855	COG3844	kynureninase activity
CEP64_RS00860	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
CEP64_RS00880	COG2188	Transcriptional regulator
CEP64_RS00885	COG2723	6-phospho-beta-galactosidase activity
CEP64_RS00900	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CEP64_RS00905	COG1280	lysine exporter protein (LysE YggA)
CEP64_RS00910	COG1132	(ABC) transporter
CEP64_RS00915	COG1132	(ABC) transporter
CEP64_RS00925	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
CEP64_RS00930	COG3189	MarR family transcriptional regulator
CEP64_RS00935	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CEP64_RS00940	COG2022	thiamine diphosphate biosynthetic process
CEP64_RS00950	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CEP64_RS00955	COG0352	thiamine-phosphate diphosphorylase activity
CEP64_RS00985	COG4509	Sortase family
CEP64_RS01005	COG3279	Response regulator of the LytR AlgR family
CEP64_RS01015	COG1733	regulation of RNA biosynthetic process
CEP64_RS01020	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
CEP64_RS01040	COG2271	Major facilitator Superfamily
CEP64_RS01045	COG1233	COG1233 Phytoene dehydrogenase and related
CEP64_RS01050	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CEP64_RS01055	COG1012	belongs to the aldehyde dehydrogenase family
CEP64_RS01070	COG1380	Effector of murein hydrolase LrgA
CEP64_RS01080	COG1278	Cold shock
CEP64_RS01090	COG0833	amino acid
CEP64_RS01095	COG2040	homocysteine
CEP64_RS01100	COG1012	belongs to the aldehyde dehydrogenase family
CEP64_RS01105	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CEP64_RS01115	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CEP64_RS01120	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
CEP64_RS01125	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CEP64_RS01155	COG0656	L-ascorbic acid biosynthetic process
CEP64_RS01160	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
CEP64_RS01165	COG3759	membrane
CEP64_RS01170	COG2409	Drug exporters of the RND superfamily
CEP64_RS01175	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
CEP64_RS01180	COG1263	PTS System
CEP64_RS01180	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CEP64_RS01185	COG1737	Transcriptional regulator
CEP64_RS01195	COG1316	TRANSCRIPTIONal
CEP64_RS01200	COG2207	Transcriptional regulator
CEP64_RS01220	COG0582	viral genome integration into host DNA
CEP64_RS01225	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CEP64_RS01225	COG2111	Na H antiporter
CEP64_RS01230	COG2111	Na H antiporter
CEP64_RS01235	COG1006	Multisubunit Na H antiporter MnhC subunit
CEP64_RS01245	COG1863	multisubunit Na H antiporter MnhE subunit
CEP64_RS01250	COG2212	antiporter activity
CEP64_RS01255	COG1320	monovalent cation:proton antiporter activity
CEP64_RS01265	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CEP64_RS01275	COG1321	iron dependent repressor
CEP64_RS01285	COG1686	Belongs to the peptidase S11 family
CEP64_RS01290	COG1132	(ABC) transporter
CEP64_RS01295	COG1620	l-lactate permease
CEP64_RS01300	COG0039	L-malate dehydrogenase activity
CEP64_RS01305	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CEP64_RS01310	COG1120	ATPase activity
CEP64_RS01315	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CEP64_RS01320	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CEP64_RS01335	COG1302	Protein conserved in bacteria
CEP64_RS01340	COG2814	Major facilitator Superfamily
CEP64_RS01345	COG3314	Sporulation integral membrane protein YlbJ
CEP64_RS01350	COG2329	Antibiotic biosynthesis monooxygenase
CEP64_RS01355	COG0300	oxidoreductase activity
CEP64_RS01370	COG2962	Rard protein
CEP64_RS01385	COG1988	membrane-bound metal-dependent
CEP64_RS01395	COG1272	protein, Hemolysin III
CEP64_RS01410	COG1574	metal-dependent hydrolase with the TIM-barrel fold
CEP64_RS01425	COG2814	Major facilitator Superfamily
CEP64_RS01430	COG0489	protein tyrosine kinase activity
CEP64_RS01435	COG2194	sulfuric ester hydrolase activity
CEP64_RS01500	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CEP64_RS01510	COG1937	Protein conserved in bacteria
CEP64_RS01515	COG2217	Heavy metal translocating P-type atpase
CEP64_RS01520	COG0586	Pfam SNARE associated Golgi protein
CEP64_RS01525	COG0456	acetyltransferase
CEP64_RS01530	COG2514	catechol 2,3-dioxygenase activity
CEP64_RS01535	COG1119	ATPase activity
CEP64_RS01540	COG0561	phosphatase activity
CEP64_RS01555	COG1388	LysM domain
CEP64_RS01555	COG3942	CHAP domain
CEP64_RS01560	COG0702	epimerase
CEP64_RS01580	COG0640	Transcriptional regulator
CEP64_RS01595	COG0477	Major facilitator Superfamily
CEP64_RS01615	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CEP64_RS01625	COG2205	protein histidine kinase activity
CEP64_RS01630	COG1136	(ABC) transporter
CEP64_RS01635	COG0577	efflux transmembrane transporter activity
CEP64_RS01640	COG1392	Phosphate transport regulator
CEP64_RS01645	COG0306	phosphate transporter
CEP64_RS01650	COG3942	CHAP domain
CEP64_RS01650	COG1388	LysM domain
CEP64_RS01655	COG0670	Belongs to the BI1 family
CEP64_RS01660	COG0217	transcriptional regulatory protein
CEP64_RS01670	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CEP64_RS01685	COG1566	PFAM secretion protein HlyD family protein
CEP64_RS01690	COG2814	Major facilitator Superfamily
CEP64_RS01705	COG0583	DNA-binding transcription factor activity
CEP64_RS01710	COG2258	MOSC domain
CEP64_RS01720	COG2839	Protein conserved in bacteria
CEP64_RS01730	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CEP64_RS01740	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CEP64_RS01745	COG1447	Phosphotransferase system cellobiose-specific component IIA
CEP64_RS01750	COG4221	oxidoreductase activity
CEP64_RS01755	COG0788	formyltetrahydrofolate deformylase activity
CEP64_RS01760	COG0598	Magnesium transport protein CorA
CEP64_RS01765	COG1940	carbohydrate kinase activity
CEP64_RS01780	COG0778	Nitroreductase
CEP64_RS01790	COG2814	Major facilitator Superfamily
CEP64_RS01795	COG1733	regulation of RNA biosynthetic process
CEP64_RS01800	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CEP64_RS01820	COG1757	Na H antiporter
CEP64_RS01825	COG0004	ammonium transporteR
CEP64_RS01830	COG1473	amidohydrolase
CEP64_RS01840	COG2814	Major facilitator Superfamily
CEP64_RS01845	COG0753	catalase activity
CEP64_RS01860	COG3048	D-serine ammonia-lyase activity
CEP64_RS01865	COG1966	Carbon starvation protein
CEP64_RS01870	COG3383	formate dehydrogenase (NAD+) activity
CEP64_RS01890	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CEP64_RS01900	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CEP64_RS01905	COG2011	ABC-type metal ion transport system permease component
CEP64_RS01910	COG1464	Belongs to the NlpA lipoprotein family
CEP64_RS01925	COG3942	CHAP domain
CEP64_RS01930	COG1757	Na H antiporter
CEP64_RS01935	COG3942	CHAP domain
CEP64_RS01995	COG1131	(ABC) transporter
CEP64_RS02000	COG1823	symporter activity
CEP64_RS02005	COG1960	acyl-CoA dehydrogenase activity
CEP64_RS02010	COG0697	spore germination
CEP64_RS02015	COG2832	Protein of unknown function (DUF454)
CEP64_RS02020	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CEP64_RS02025	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CEP64_RS02035	COG2186	Transcriptional regulator
CEP64_RS02040	COG2186	Transcriptional regulator
CEP64_RS02050	COG1268	BioY protein
CEP64_RS02060	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
CEP64_RS02065	COG3383	formate dehydrogenase (NAD+) activity
CEP64_RS02075	COG4149	molybdate abc transporter
CEP64_RS02080	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
CEP64_RS02085	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
CEP64_RS02090	COG1140	nitrate reductase beta subunit
CEP64_RS02095	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
CEP64_RS02100	COG2181	nitrate reductase activity
CEP64_RS02110	COG4585	Histidine kinase
CEP64_RS02115	COG2197	response regulator
CEP64_RS02120	COG2223	nitrite transmembrane transporter activity
CEP64_RS02125	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CEP64_RS02130	COG0521	Mo-molybdopterin cofactor biosynthetic process
CEP64_RS02135	COG0315	cyclic pyranopterin monophosphate synthase activity
CEP64_RS02140	COG0303	'Molybdopterin
CEP64_RS02145	COG1763	Mo-molybdopterin cofactor biosynthetic process
CEP64_RS02160	COG0746	molybdenum cofactor guanylyltransferase activity
CEP64_RS02165	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CEP64_RS02170	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CEP64_RS02175	COG2814	Major facilitator Superfamily
CEP64_RS02190	COG2348	transferase activity, transferring amino-acyl groups
CEP64_RS02195	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CEP64_RS02200	COG0436	Aminotransferase
CEP64_RS02215	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CEP64_RS02230	COG4975	Glucose uptake
CEP64_RS02245	COG2252	PERMEase
CEP64_RS02255	COG0051	transcription antitermination factor activity, RNA binding
CEP64_RS02260	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CEP64_RS02265	COG0088	Forms part of the polypeptide exit tunnel
CEP64_RS02270	COG0089	rRNA binding
CEP64_RS02275	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CEP64_RS02280	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CEP64_RS02285	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CEP64_RS02290	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CEP64_RS02295	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CEP64_RS02300	COG0255	Belongs to the universal ribosomal protein uL29 family
CEP64_RS02310	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CEP64_RS02315	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CEP64_RS02320	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CEP64_RS02325	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CEP64_RS02330	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CEP64_RS02335	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CEP64_RS02340	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CEP64_RS02345	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CEP64_RS02350	COG1841	ribosomal large subunit assembly
CEP64_RS02360	COG0201	protein transport
CEP64_RS02375	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CEP64_RS02380	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CEP64_RS02390	COG0202	RNA polymerase activity
CEP64_RS02395	COG0203	ribosomal protein L17
CEP64_RS02400	COG1122	ATPase activity
CEP64_RS02415	COG0101	tRNA pseudouridine synthase activity
CEP64_RS02420	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CEP64_RS02425	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CEP64_RS02430	COG1011	Hydrolase
CEP64_RS02440	COG3655	Transcriptional regulator
CEP64_RS02445	COG0346	lactoylglutathione lyase activity
CEP64_RS02465	COG0604	alcohol dehydrogenase
CEP64_RS02470	COG1511	domain protein
CEP64_RS02480	COG3842	ATPase activity
CEP64_RS02485	COG2182	Extracellular solute-binding protein
CEP64_RS02490	COG1175	transmembrane transport
CEP64_RS02495	COG3833	ABC-type maltose transport systems, permease component
CEP64_RS02500	COG1609	Transcriptional regulator
CEP64_RS02505	COG0366	Alpha amylase catalytic
CEP64_RS02510	COG2376	Dihydroxyacetone kinase
CEP64_RS02515	COG1461	Dihydroxyacetone kinase
CEP64_RS02520	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
CEP64_RS02525	COG2186	Transcriptional regulator
CEP64_RS02530	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
CEP64_RS02535	COG1482	cell wall glycoprotein biosynthetic process
CEP64_RS02545	COG3942	CHAP domain
CEP64_RS02545	COG1388	LysM domain
CEP64_RS02555	COG1115	amino acid carrier protein
CEP64_RS02565	COG1757	Na H antiporter
CEP64_RS02575	COG1609	Transcriptional regulator
CEP64_RS02580	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CEP64_RS02585	COG1869	D-ribose catabolic process
CEP64_RS02590	COG1129	ABC transporter
CEP64_RS02595	COG1172	Belongs to the binding-protein-dependent transport system permease family
CEP64_RS02600	COG1879	ABC-type sugar transport system periplasmic component
CEP64_RS02605	COG0783	Belongs to the Dps family
CEP64_RS02610	COG0277	FAD linked oxidase domain protein
CEP64_RS02615	COG0247	lactate metabolic process
CEP64_RS02620	COG0813	purine-nucleoside phosphorylase activity
CEP64_RS02625	COG2390	Transcriptional regulator
CEP64_RS02630	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
CEP64_RS02640	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
CEP64_RS02650	COG1854	S-ribosylhomocysteine lyase activity
CEP64_RS02655	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
CEP64_RS02655	COG0456	acetyltransferase
CEP64_RS02695	COG5146	pantothenate kinase activity
CEP64_RS02700	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CEP64_RS02705	COG4589	Belongs to the CDS family
CEP64_RS02730	COG3343	RNA polymerase activity
CEP64_RS02735	COG0504	CTP synthase activity
CEP64_RS02740	COG4821	SIS domain
CEP64_RS02750	COG0191	fructose-bisphosphate aldolase activity
CEP64_RS02755	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CEP64_RS02765	COG1012	belongs to the aldehyde dehydrogenase family
CEP64_RS02770	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CEP64_RS02775	COG0254	rRNA binding
CEP64_RS02780	COG1435	thymidine kinase activity
CEP64_RS02790	COG2890	protein-(glutamine-N5) methyltransferase activity
CEP64_RS02795	COG0009	L-threonylcarbamoyladenylate synthase
CEP64_RS02800	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CEP64_RS02805	COG0698	ribose 5-phosphate isomerase
CEP64_RS02810	COG4475	Protein of unknown function (DUF436)
CEP64_RS02815	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CEP64_RS02820	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CEP64_RS02825	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CEP64_RS02835	COG0356	it plays a direct role in the translocation of protons across the membrane
CEP64_RS02840	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CEP64_RS02845	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CEP64_RS02850	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CEP64_RS02855	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CEP64_RS02860	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CEP64_RS02865	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CEP64_RS02890	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CEP64_RS02900	COG0629	single-stranded DNA binding
CEP64_RS02905	COG1388	LysM domain
CEP64_RS02915	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
CEP64_RS02920	COG0352	thiamine-phosphate diphosphorylase activity
CEP64_RS02925	COG0706	membrane insertase activity
CEP64_RS02930	COG1418	mRNA catabolic process
CEP64_RS02935	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CEP64_RS02945	COG0772	Belongs to the SEDS family
CEP64_RS02950	COG1181	Belongs to the D-alanine--D-alanine ligase family
CEP64_RS02955	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CEP64_RS02965	COG0513	Belongs to the DEAD box helicase family
CEP64_RS03005	COG2208	phosphoserine phosphatase activity
CEP64_RS03020	COG1191	sigma factor activity
CEP64_RS03025	COG2183	response to ionizing radiation
CEP64_RS03030	COG3091	SprT-like family
CEP64_RS03060	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CEP64_RS03070	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CEP64_RS03075	COG0473	3-isopropylmalate dehydrogenase activity
CEP64_RS03080	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CEP64_RS03085	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
CEP64_RS03095	COG0028	Belongs to the TPP enzyme family
CEP64_RS03100	COG0129	dihydroxy-acid dehydratase activity
CEP64_RS03105	COG0802	atpase or kinase
CEP64_RS03110	COG1214	PFAM Peptidase M22, glycoprotease
CEP64_RS03115	COG0456	acetyltransferase
CEP64_RS03120	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CEP64_RS03130	COG0488	(ABC) transporter
CEP64_RS03135	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
CEP64_RS03140	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CEP64_RS03145	COG0805	protein transport
CEP64_RS03150	COG2391	methyltransferase activity
CEP64_RS03155	COG0425	Belongs to the sulfur carrier protein TusA family
CEP64_RS03160	COG1609	Transcriptional regulator
CEP64_RS03165	COG1621	beta-fructofuranosidase activity
CEP64_RS03195	COG0459	protein refolding
CEP64_RS03205	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CEP64_RS03225	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CEP64_RS03230	COG1131	(ABC) transporter
CEP64_RS03245	COG1131	(ABC) transporter
CEP64_RS03260	COG1473	amidohydrolase
CEP64_RS03265	COG1802	Transcriptional regulator
CEP64_RS03270	COG1070	Carbohydrate kinase
CEP64_RS03275	COG2610	gluconate transmembrane transporter activity
CEP64_RS03280	COG2223	nitrite transmembrane transporter activity
CEP64_RS03310	COG0385	Bile acid
CEP64_RS03350	COG4512	PFAM Accessory gene regulator B
CEP64_RS03355	COG2706	6-phosphogluconolactonase activity
CEP64_RS03365	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CEP64_RS03370	COG0390	transport system, permease component
CEP64_RS03375	COG1012	belongs to the aldehyde dehydrogenase family
CEP64_RS03380	COG0673	inositol 2-dehydrogenase activity
CEP64_RS03395	COG1227	inorganic diphosphatase activity
CEP64_RS03400	COG1335	isochorismatase
CEP64_RS03415	COG0077	Prephenate dehydratase
CEP64_RS03430	COG0107	imidazoleglycerol-phosphate synthase activity
CEP64_RS03435	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
CEP64_RS03440	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CEP64_RS03445	COG0131	Imidazoleglycerol-phosphate dehydratase
CEP64_RS03450	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CEP64_RS03455	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CEP64_RS03460	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
CEP64_RS03465	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
CEP64_RS03470	COG0477	Major facilitator Superfamily
CEP64_RS03475	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CEP64_RS03480	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CEP64_RS03485	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
CEP64_RS03495	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CEP64_RS03500	COG4496	protein, YerC YecD
CEP64_RS03505	COG1876	peptidase activity
CEP64_RS03510	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
CEP64_RS03515	COG0210	DNA helicase
CEP64_RS03520	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CEP64_RS03525	COG4851	CamS sex pheromone cAM373 precursor
CEP64_RS03530	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CEP64_RS03535	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CEP64_RS03545	COG0154	amidase activity
CEP64_RS03550	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CEP64_RS03555	COG0433	COG0433 Predicted ATPase
CEP64_RS03560	COG1597	lipid kinase activity
CEP64_RS03580	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CEP64_RS03595	COG1528	Iron-storage protein
CEP64_RS03610	COG4129	membrane
CEP64_RS03615	COG0024	Methionine aminopeptidase
CEP64_RS03635	COG2197	response regulator
CEP64_RS03640	COG0288	reversible hydration of carbon dioxide
CEP64_RS03645	COG1295	ribonuclease BN
CEP64_RS03660	COG4840	Belongs to the UPF0435 family
CEP64_RS03665	COG2309	aminopeptidase activity
CEP64_RS03675	COG1607	acyl-coa hydrolase
CEP64_RS03680	COG0535	radical SAM domain protein
CEP64_RS03690	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CEP64_RS03695	COG0693	protein deglycase activity
CEP64_RS03705	COG0028	Belongs to the TPP enzyme family
CEP64_RS03710	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CEP64_RS03715	COG2137	regulation of response to DNA damage stimulus
CEP64_RS03725	COG1134	teichoic acid transport
CEP64_RS03735	COG1988	membrane-bound metal-dependent
CEP64_RS03740	COG1194	a g-specific adenine glycosylase
CEP64_RS03745	COG3557	Belongs to the UPF0374 family
CEP64_RS03755	COG0069	glutamate synthase activity
CEP64_RS03760	COG4129	membrane
CEP64_RS03765	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
CEP64_RS03770	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CEP64_RS03775	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CEP64_RS03780	COG0735	belongs to the Fur family
CEP64_RS03930	COG1609	Transcriptional regulator
CEP64_RS03960	COG1904	glucuronate isomerase
CEP64_RS03965	COG1501	Belongs to the glycosyl hydrolase 31 family
CEP64_RS03975	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CEP64_RS03980	COG0765	amino acid transport
CEP64_RS03985	COG1126	abc transporter atp-binding protein
CEP64_RS03990	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CEP64_RS03995	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
CEP64_RS04000	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CEP64_RS04005	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CEP64_RS04010	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
CEP64_RS04015	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CEP64_RS04020	COG0363	glucosamine-6-phosphate deaminase activity
CEP64_RS04025	COG0114	fumarate hydratase activity
CEP64_RS04030	COG0248	Ppx GppA phosphatase
CEP64_RS04035	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
CEP64_RS04040	COG0564	pseudouridine synthase activity
CEP64_RS04045	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CEP64_RS04045	COG3153	acetyltransferase
CEP64_RS04050	COG2203	Gaf domain
CEP64_RS04050	COG4585	Histidine kinase
CEP64_RS04055	COG2197	response regulator
CEP64_RS04060	COG1301	dicarboxylic acid transport
CEP64_RS04070	COG4399	Belongs to the UPF0754 family
CEP64_RS04075	COG3679	Belongs to the UPF0342 family
CEP64_RS04080	COG0420	3'-5' exonuclease activity
CEP64_RS04090	COG3481	metal-dependent phosphohydrolase, HD sub domain
CEP64_RS04095	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CEP64_RS04105	COG1846	Transcriptional regulator
CEP64_RS04115	COG0537	adenosine 5'-monophosphoramidase activity
CEP64_RS04120	COG1131	(ABC) transporter
CEP64_RS04130	COG2329	Antibiotic biosynthesis monooxygenase
CEP64_RS04135	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
CEP64_RS04140	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
CEP64_RS04145	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
CEP64_RS04210	COG0697	spore germination
CEP64_RS04215	COG0456	acetyltransferase
CEP64_RS04225	COG2814	Major facilitator Superfamily
CEP64_RS04250	COG0494	nUDIX hydrolase
CEP64_RS04255	COG1506	peptidase
CEP64_RS04260	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
CEP64_RS04265	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CEP64_RS04275	COG1012	belongs to the aldehyde dehydrogenase family
CEP64_RS04280	COG0656	L-ascorbic acid biosynthetic process
CEP64_RS04285	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CEP64_RS04305	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CEP64_RS04310	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CEP64_RS04325	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CEP64_RS04350	COG1595	DNA-templated transcription, initiation
CEP64_RS04395	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CEP64_RS04395	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CEP64_RS04400	COG0307	riboflavin synthase, alpha
CEP64_RS04415	COG0506	proline dehydrogenase activity
CEP64_RS04430	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CEP64_RS04435	COG2267	carboxylic ester hydrolase activity
CEP64_RS04445	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
CEP64_RS04450	COG1242	4 iron, 4 sulfur cluster binding
CEP64_RS04455	COG2814	Major facilitator Superfamily
CEP64_RS04460	COG0495	leucyl-tRNA aminoacylation
CEP64_RS04465	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CEP64_RS04470	COG2081	HI0933 family
CEP64_RS04475	COG2244	polysaccharide biosynthetic process
CEP64_RS04480	COG1187	pseudouridine synthase activity
CEP64_RS04500	COG0510	thiamine kinase activity
CEP64_RS04505	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CEP64_RS04510	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CEP64_RS04515	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
CEP64_RS04525	COG1363	Peptidase, m42
CEP64_RS04530	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CEP64_RS04535	COG0765	amino acid transport
CEP64_RS04540	COG1126	abc transporter atp-binding protein
CEP64_RS04550	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CEP64_RS04555	COG4848	Belongs to the UPF0354 family
CEP64_RS04560	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CEP64_RS04565	COG1674	ftsk spoiiie
CEP64_RS04570	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CEP64_RS04575	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
CEP64_RS04580	COG4980	gas vesicle protein
CEP64_RS04585	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
CEP64_RS04585	COG1605	Chorismate mutase
CEP64_RS04590	COG1609	Transcriptional regulator
CEP64_RS04595	COG0123	including yeast histone deacetylase and acetoin utilization protein
CEP64_RS04600	COG0517	IMP dehydrogenase activity
CEP64_RS04605	COG0454	-acetyltransferase
CEP64_RS04610	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CEP64_RS04620	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CEP64_RS04625	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CEP64_RS04630	COG1704	LemA family
CEP64_RS04640	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CEP64_RS04645	COG0204	Acyl-transferase
CEP64_RS04660	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CEP64_RS04670	COG1764	response to oxidative stress
CEP64_RS04680	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CEP64_RS04685	COG1956	GAF domain-containing protein
CEP64_RS04690	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
CEP64_RS04695	COG1104	cysteine desulfurase activity
CEP64_RS04700	COG0301	tRNA thio-modification
CEP64_RS04710	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CEP64_RS04715	COG0616	signal peptide processing
CEP64_RS04720	COG1714	RDD family
CEP64_RS04725	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
CEP64_RS04730	COG0827	DNA restriction-modification system
CEP64_RS04735	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CEP64_RS04740	COG0589	response to stress
CEP64_RS04745	COG0686	Belongs to the AlaDH PNT family
CEP64_RS04755	COG3142	Participates in the control of copper homeostasis
CEP64_RS04760	COG0006	proline dipeptidase activity
CEP64_RS04765	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
CEP64_RS04770	COG4109	DRTGG domain
CEP64_RS04780	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
CEP64_RS04790	COG0281	malic enzyme
CEP64_RS04795	COG1725	Transcriptional regulator
CEP64_RS04800	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
CEP64_RS04805	COG0825	malonyl-CoA metabolic process
CEP64_RS04810	COG0205	6-phosphofructokinase activity
CEP64_RS04815	COG0469	pyruvate kinase activity
CEP64_RS04820	COG1113	amino acid transport
CEP64_RS04825	COG0372	Belongs to the citrate synthase family
CEP64_RS04830	COG0538	isocitrate dehydrogenase activity
CEP64_RS04840	COG0745	RESPONSE REGULATOR receiver
CEP64_RS04845	COG5002	protein histidine kinase activity
CEP64_RS04850	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CEP64_RS04850	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CEP64_RS04855	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CEP64_RS04860	COG0237	dephospho-CoA kinase activity
CEP64_RS04865	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CEP64_RS04875	COG3611	Membrane attachment protein
CEP64_RS04880	COG1484	DNA-dependent DNA replication
CEP64_RS04890	COG0833	amino acid
CEP64_RS04895	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CEP64_RS04900	COG0291	Belongs to the bacterial ribosomal protein bL35 family
CEP64_RS04905	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CEP64_RS04910	COG4112	unkown
CEP64_RS04920	COG0544	peptidyl-prolyl cis-trans isomerase activity
CEP64_RS04925	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CEP64_RS04930	COG0218	Necessary for normal cell division and for the maintenance of normal septation
CEP64_RS04935	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
CEP64_RS04940	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CEP64_RS04945	COG0181	hydroxymethylbilane synthase activity
CEP64_RS04960	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
CEP64_RS04975	COG0285	dihydrofolate synthase activity
CEP64_RS04980	COG1288	antiporter activity
CEP64_RS04990	COG2003	Belongs to the UPF0758 family
CEP64_RS05000	COG1132	(ABC) transporter
CEP64_RS05005	COG1132	(ABC) transporter
CEP64_RS05015	COG1792	Involved in formation and maintenance of cell shape
CEP64_RS05025	COG0261	This protein binds to 23S rRNA in the presence of protein L20
CEP64_RS05030	COG2868	ribosomal protein
CEP64_RS05035	COG0211	Belongs to the bacterial ribosomal protein bL27 family
CEP64_RS05045	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CEP64_RS05050	COG4492	Belongs to the UPF0735 family
CEP64_RS05055	COG0632	four-way junction helicase activity
CEP64_RS05060	COG2255	four-way junction helicase activity
CEP64_RS05070	COG0343	queuine tRNA-ribosyltransferase activity
CEP64_RS05075	COG1862	Preprotein translocase
CEP64_RS05080	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CEP64_RS05080	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CEP64_RS05085	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CEP64_RS05085	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
CEP64_RS05095	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CEP64_RS05105	COG0860	N-Acetylmuramoyl-L-alanine amidase
CEP64_RS05110	COG0124	histidyl-tRNA synthetase
CEP64_RS05115	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CEP64_RS05125	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CEP64_RS05130	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CEP64_RS05135	COG1959	2 iron, 2 sulfur cluster binding
CEP64_RS05145	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CEP64_RS05150	COG0488	(ABC) transporter
CEP64_RS05155	COG1104	cysteine desulfurase activity
CEP64_RS05160	COG0482	sulfurtransferase activity
CEP64_RS05170	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CEP64_RS05175	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CEP64_RS05180	COG4472	Bacterial protein of unknown function (DUF965)
CEP64_RS05185	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CEP64_RS05195	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CEP64_RS05200	COG4122	O-methyltransferase activity
CEP64_RS05205	COG0826	peptidase U32
CEP64_RS05210	COG0826	peptidase U32
CEP64_RS05215	COG0572	uridine kinase
CEP64_RS05220	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CEP64_RS05225	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
CEP64_RS05230	COG1984	allophanate hydrolase subunit 2
CEP64_RS05240	COG0439	Biotin carboxylase
CEP64_RS05250	COG1914	H( )-stimulated, divalent metal cation uptake system
CEP64_RS05255	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CEP64_RS05260	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
CEP64_RS05265	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
CEP64_RS05275	COG1534	Rna-binding protein
CEP64_RS05280	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CEP64_RS05285	COG1713	HD superfamily hydrolase involved in NAD metabolism
CEP64_RS05290	COG0799	negative regulation of ribosome biogenesis
CEP64_RS05295	COG2226	methyltransferase
CEP64_RS05300	COG1596	polysaccharide export
CEP64_RS05300	COG1555	photosystem II stabilization
CEP64_RS05305	COG2131	deaminase
CEP64_RS05310	COG0658	competence protein
CEP64_RS05310	COG2333	competence protein COMEC
CEP64_RS05320	COG1466	dna polymerase III delta subunit
CEP64_RS05325	COG0268	Binds directly to 16S ribosomal RNA
CEP64_RS05330	COG0481	GTPase activity
CEP64_RS05335	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CEP64_RS05345	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CEP64_RS05350	COG0443	Heat shock 70 kDa protein
CEP64_RS05360	COG2264	protein methyltransferase activity
CEP64_RS05365	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CEP64_RS05370	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CEP64_RS05375	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CEP64_RS05380	COG1030	water channel activity
CEP64_RS05385	COG4864	UPF0365 protein
CEP64_RS05400	COG1702	phosphate starvation-inducible protein PhoH
CEP64_RS05405	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CEP64_RS05410	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
CEP64_RS05415	COG0295	cytidine deaminase activity
CEP64_RS05425	COG1381	Involved in DNA repair and RecF pathway recombination
CEP64_RS05430	COG0423	glycine-tRNA ligase activity
CEP64_RS05435	COG0517	IMP dehydrogenase activity
CEP64_RS05440	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
CEP64_RS05445	COG0358	DNA primase activity
CEP64_RS05450	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CEP64_RS05455	COG2010	Cytochrome c
CEP64_RS05460	COG2384	SAM-dependent methyltransferase
CEP64_RS05465	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CEP64_RS05470	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
CEP64_RS05475	COG0513	Belongs to the DEAD box helicase family
CEP64_RS05480	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
CEP64_RS05485	COG1121	(ABC) transporter
CEP64_RS05490	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CEP64_RS05495	COG0735	belongs to the Fur family
CEP64_RS05500	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
CEP64_RS05505	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
CEP64_RS05515	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CEP64_RS05520	COG0768	penicillin binding
CEP64_RS05525	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CEP64_RS05530	COG0573	inorganic phosphate transmembrane transporter activity
CEP64_RS05535	COG0581	inorganic phosphate transmembrane transporter activity
CEP64_RS05540	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CEP64_RS05545	COG0704	Plays a role in the regulation of phosphate uptake
CEP64_RS05550	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CEP64_RS05555	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CEP64_RS05560	COG0457	Tetratricopeptide repeat
CEP64_RS05560	COG0705	Rhomboid family
CEP64_RS05565	COG4483	Protein conserved in bacteria
CEP64_RS05570	COG1940	carbohydrate kinase activity
CEP64_RS05575	COG0011	TIGRFAM Protein of
CEP64_RS05585	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CEP64_RS05595	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CEP64_RS05600	COG1459	type II secretion system
CEP64_RS05630	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CEP64_RS05635	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CEP64_RS05645	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CEP64_RS05650	COG0095	Lipoate-protein ligase
CEP64_RS05665	COG0006	proline dipeptidase activity
CEP64_RS05670	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CEP64_RS05675	COG0511	ligase activity, forming carbon-carbon bonds
CEP64_RS05680	COG0439	Biotin carboxylase
CEP64_RS05685	COG1302	Protein conserved in bacteria
CEP64_RS05710	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CEP64_RS05715	COG1438	arginine binding
CEP64_RS05720	COG0497	DNA recombination
CEP64_RS05735	COG0280	phosphate acetyltransferase
CEP64_RS05750	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CEP64_RS05755	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CEP64_RS05760	COG0022	dehydrogenase e1 component
CEP64_RS05765	COG0508	dehydrogenase complex catalyzes the overall conversion of
CEP64_RS05775	COG4129	membrane
CEP64_RS05780	COG2195	Cleaves the N-terminal amino acid of tripeptides
CEP64_RS05790	COG2207	Transcriptional regulator
CEP64_RS05790	COG1917	Cupin 2, conserved barrel domain protein
CEP64_RS05795	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CEP64_RS05800	COG1234	tRNA 3'-trailer cleavage
CEP64_RS05805	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CEP64_RS05815	COG0667	Aldo Keto reductase
CEP64_RS05825	COG0735	belongs to the Fur family
CEP64_RS05830	COG4974	Belongs to the 'phage' integrase family
CEP64_RS05835	COG1547	Domain of unknown function (DUF309)
CEP64_RS05840	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
CEP64_RS05845	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CEP64_RS05850	COG1187	pseudouridine synthase activity
CEP64_RS05855	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CEP64_RS05860	COG1333	cytochrome c biogenesis protein
CEP64_RS05865	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CEP64_RS05870	COG0745	RESPONSE REGULATOR receiver
CEP64_RS05875	COG5002	protein histidine kinase activity
CEP64_RS05885	COG1141	Ferredoxin
CEP64_RS05890	COG4955	Helix-turn-helix domain
CEP64_RS05895	COG0514	ATP-dependent DNA helicase (RecQ)
CEP64_RS05910	COG0492	ferredoxin-NADP+ reductase activity
CEP64_RS05915	COG0252	asparaginase activity
CEP64_RS05920	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
CEP64_RS05925	COG0539	negative regulation of cytoplasmic translation
CEP64_RS05930	COG1160	GTP binding
CEP64_RS05935	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CEP64_RS05960	COG2226	methyltransferase
CEP64_RS05965	COG0142	geranyltranstransferase activity
CEP64_RS05970	COG0105	UTP biosynthetic process
CEP64_RS05975	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CEP64_RS05980	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CEP64_RS05985	COG0457	Tetratricopeptide repeat
CEP64_RS06000	COG0723	plastoquinol--plastocyanin reductase activity
CEP64_RS06005	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
CEP64_RS06015	COG4347	Protein of unknown function (DUF1405)
CEP64_RS06020	COG2738	Putative neutral zinc metallopeptidase
CEP64_RS06025	COG1694	Mazg nucleotide pyrophosphohydrolase
CEP64_RS06030	COG0438	transferase activity, transferring glycosyl groups
CEP64_RS06035	COG0617	tRNA 3'-terminal CCA addition
CEP64_RS06045	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CEP64_RS06045	COG1199	ATP-dependent helicase activity
CEP64_RS06055	COG3935	DnaD domain protein
CEP64_RS06060	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CEP64_RS06070	COG4499	WXG100 protein secretion system (Wss), protein YukC
CEP64_RS06070	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CEP64_RS06075	COG3331	DNA recombination
CEP64_RS06085	COG4474	Belongs to the UPF0398 family
CEP64_RS06090	COG3599	regulation of cell shape
CEP64_RS06100	COG0116	Belongs to the methyltransferase superfamily
CEP64_RS06105	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CEP64_RS06115	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
CEP64_RS06120	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CEP64_RS06125	COG0328	RNA-DNA hybrid ribonuclease activity
CEP64_RS06140	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
CEP64_RS06150	COG1413	lyase activity
CEP64_RS06175	COG0204	Acyl-transferase
CEP64_RS06195	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CEP64_RS06200	COG2190	(PTS) system
CEP64_RS06205	COG4479	Belongs to the UPF0346 family
CEP64_RS06210	COG0793	Belongs to the peptidase S41A family
CEP64_RS06225	COG0671	phosphoesterase, PA-phosphatase related
CEP64_RS06235	COG5002	protein histidine kinase activity
CEP64_RS06240	COG0567	Dehydrogenase, E1 component
CEP64_RS06260	COG0714	Associated with various cellular activities
CEP64_RS06265	COG4548	von Willebrand factor, type A
CEP64_RS06270	COG1114	Component of the transport system for branched-chain amino acids
CEP64_RS06275	COG5505	Protein of unknown function (DUF819)
CEP64_RS06280	COG3853	Toxic anion resistance protein (TelA)
CEP64_RS06290	COG1254	Belongs to the acylphosphatase family
CEP64_RS06325	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
CEP64_RS06330	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CEP64_RS06335	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CEP64_RS06340	COG0527	aspartate kinase activity
CEP64_RS06345	COG0488	(ABC) transporter
CEP64_RS06350	COG2996	Protein conserved in bacteria
CEP64_RS06355	COG3711	transcriptional antiterminator
CEP64_RS06360	COG1447	Phosphotransferase system cellobiose-specific component IIA
CEP64_RS06365	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CEP64_RS06365	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CEP64_RS06370	COG2723	6-phospho-beta-galactosidase activity
CEP64_RS06375	COG3684	Belongs to the aldolase LacD family
CEP64_RS06380	COG1105	Belongs to the carbohydrate kinase PfkB family
CEP64_RS06395	COG1349	DNA-binding transcription factor activity
CEP64_RS06400	COG1164	Oligoendopeptidase f
CEP64_RS06415	COG0789	Transcriptional regulator
CEP64_RS06440	COG0159	tryptophan synthase activity
CEP64_RS06445	COG0133	tryptophan synthase activity
CEP64_RS06450	COG0135	phosphoribosylanthranilate isomerase activity
CEP64_RS06460	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CEP64_RS06465	COG0512	Glutamine amidotransferase of anthranilate synthase
CEP64_RS06470	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CEP64_RS06475	COG1363	Peptidase, m42
CEP64_RS06480	COG0287	Prephenate dehydrogenase
CEP64_RS06490	COG1476	TRANSCRIPTIONal
CEP64_RS06495	COG1757	Na H antiporter
CEP64_RS06500	COG1929	Belongs to the glycerate kinase type-1 family
CEP64_RS06510	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CEP64_RS06545	COG0586	Pfam SNARE associated Golgi protein
CEP64_RS06555	COG0628	permease
CEP64_RS06560	COG2190	(PTS) system
CEP64_RS06560	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CEP64_RS06560	COG1263	PTS System
CEP64_RS06565	COG3711	transcriptional antiterminator
CEP64_RS06575	COG1115	amino acid carrier protein
CEP64_RS06580	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CEP64_RS06590	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
CEP64_RS06595	COG4841	protein insertion into membrane
CEP64_RS06600	COG0824	Thioesterase
CEP64_RS06610	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CEP64_RS06615	COG1970	mechanosensitive ion channel activity
CEP64_RS06620	COG1999	signal sequence binding
CEP64_RS06640	COG4846	Membrane protein involved in cytochrome C biogenesis
CEP64_RS06645	COG0785	Cytochrome C biogenesis protein
CEP64_RS06650	COG3763	UPF0154 protein
CEP64_RS06660	COG4224	UPF0291 protein
CEP64_RS06670	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CEP64_RS06680	COG0516	GMP reductase activity
CEP64_RS06685	COG0803	Belongs to the bacterial solute-binding protein 9 family
CEP64_RS06690	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CEP64_RS06695	COG0833	amino acid
CEP64_RS06710	COG0561	phosphatase activity
CEP64_RS06715	COG0083	homoserine kinase activity
CEP64_RS06720	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
CEP64_RS06725	COG0460	homoserine dehydrogenase
CEP64_RS06730	COG0527	aspartate kinase activity
CEP64_RS06745	COG2084	Dehydrogenase
CEP64_RS06755	COG1597	lipid kinase activity
CEP64_RS06790	COG0110	maltose O-acetyltransferase activity
CEP64_RS06805	COG0789	Transcriptional regulator
CEP64_RS06810	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
CEP64_RS06815	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CEP64_RS06820	COG0386	Belongs to the glutathione peroxidase family
CEP64_RS06825	COG1923	regulation of RNA biosynthetic process
CEP64_RS06830	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CEP64_RS06835	COG2267	carboxylic ester hydrolase activity
CEP64_RS06840	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CEP64_RS06845	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CEP64_RS06850	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CEP64_RS06855	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
CEP64_RS06860	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CEP64_RS06865	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CEP64_RS06875	COG4550	Control of competence regulator ComK, YlbF/YmcA
CEP64_RS06880	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CEP64_RS06890	COG1132	(ABC) transporter
CEP64_RS06895	COG1132	(ABC) transporter
CEP64_RS06905	COG1013	pyruvate-flavodoxin oxidoreductase activity
CEP64_RS06910	COG0674	pyruvate-flavodoxin oxidoreductase activity
CEP64_RS06910	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
CEP64_RS06915	COG1692	metallophosphoesterase
CEP64_RS06925	COG0463	Glycosyl transferase, family 2
CEP64_RS06925	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
CEP64_RS06950	COG0500	methyltransferase
CEP64_RS06955	COG0561	phosphatase activity
CEP64_RS06960	COG1917	Cupin 2, conserved barrel domain protein
CEP64_RS06960	COG2207	Transcriptional regulator
CEP64_RS06965	COG0697	spore germination
CEP64_RS07000	COG0596	Alpha beta hydrolase
CEP64_RS07010	COG1215	transferase activity, transferring glycosyl groups
CEP64_RS07015	COG3177	Filamentation induced by cAMP protein fic
CEP64_RS07020	COG1418	mRNA catabolic process
CEP64_RS07025	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CEP64_RS07030	COG1546	Belongs to the CinA family
CEP64_RS07030	COG1058	Belongs to the CinA family
CEP64_RS07050	COG0300	oxidoreductase activity
CEP64_RS07055	COG0612	Peptidase, M16
CEP64_RS07065	COG2188	Transcriptional regulator
CEP64_RS07075	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
CEP64_RS07080	COG0612	Peptidase, M16
CEP64_RS07085	COG1185	polyribonucleotide nucleotidyltransferase activity
CEP64_RS07095	COG0196	riboflavin kinase activity
CEP64_RS07100	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CEP64_RS07105	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CEP64_RS07110	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
CEP64_RS07115	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CEP64_RS07115	COG1263	PTS System
CEP64_RS07135	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CEP64_RS07140	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CEP64_RS07145	COG2169	Transcriptional regulator
CEP64_RS07155	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CEP64_RS07160	COG1358	cellular component organization or biogenesis
CEP64_RS07165	COG2740	Nucleic-acid-binding protein implicated in transcription termination
CEP64_RS07170	COG0195	Participates in both transcription termination and antitermination
CEP64_RS07175	COG0779	Required for maturation of 30S ribosomal subunits
CEP64_RS07185	COG0442	prolyl-tRNA aminoacylation
CEP64_RS07195	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
CEP64_RS07200	COG4589	Belongs to the CDS family
CEP64_RS07210	COG0233	cytoplasmic translational termination
CEP64_RS07215	COG0528	UMP kinase activity
CEP64_RS07220	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CEP64_RS07225	COG0052	Belongs to the universal ribosomal protein uS2 family
CEP64_RS07235	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
CEP64_RS07240	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
CEP64_RS07245	COG4974	Belongs to the 'phage' integrase family
CEP64_RS07250	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
CEP64_RS07255	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CEP64_RS07260	COG0758	DNA mediated transformation
CEP64_RS07265	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CEP64_RS07270	COG0045	succinate-CoA ligase (ADP-forming) activity
CEP64_RS07275	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CEP64_RS07285	COG0463	Glycosyl transferase, family 2
CEP64_RS07290	COG4485	Bacterial membrane protein, YfhO
CEP64_RS07295	COG0335	large ribosomal subunit rRNA binding
CEP64_RS07300	COG0336	Belongs to the RNA methyltransferase TrmD family
CEP64_RS07310	COG1837	Belongs to the UPF0109 family
CEP64_RS07315	COG0228	four-way junction DNA binding
CEP64_RS07320	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CEP64_RS07325	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
CEP64_RS07330	COG0552	protein localization to endoplasmic reticulum
CEP64_RS07335	COG1196	nuclear chromosome segregation
CEP64_RS07355	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CEP64_RS07370	COG0416	fatty acid biosynthetic process
CEP64_RS07375	COG1349	DNA-binding transcription factor activity
CEP64_RS07380	COG3764	Sortase (surface protein transpeptidase)
CEP64_RS07385	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CEP64_RS07390	COG1760	l-serine dehydratase
CEP64_RS07395	COG1760	l-serine dehydratase
CEP64_RS07405	COG1302	Protein conserved in bacteria
CEP64_RS07410	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CEP64_RS07415	COG1564	THIamine pyrophosphokinase
CEP64_RS07420	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CEP64_RS07425	COG1162	GTPase activity
CEP64_RS07430	COG3850	Histidine kinase
CEP64_RS07430	COG5002	protein histidine kinase activity
CEP64_RS07435	COG0745	RESPONSE REGULATOR receiver
CEP64_RS07440	COG2124	cytochrome p450
CEP64_RS07460	COG0820	rRNA (adenine-C2-)-methyltransferase activity
CEP64_RS07465	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CEP64_RS07465	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CEP64_RS07470	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CEP64_RS07475	COG0242	peptide deformylase activity
CEP64_RS07490	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CEP64_RS07495	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CEP64_RS07500	COG1758	RNA polymerase activity
CEP64_RS07535	COG0284	orotidine-5'-phosphate decarboxylase activity
CEP64_RS07540	COG0167	dihydroorotate dehydrogenase activity
CEP64_RS07545	COG0543	2 iron, 2 sulfur cluster binding
CEP64_RS07550	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CEP64_RS07555	COG0505	Belongs to the CarA family
CEP64_RS07565	COG0540	Belongs to the ATCase OTCase family
CEP64_RS07575	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
CEP64_RS07580	COG0564	pseudouridine synthase activity
CEP64_RS07585	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CEP64_RS07600	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CEP64_RS07605	COG3599	regulation of cell shape
CEP64_RS07615	COG0762	integral membrane protein
CEP64_RS07620	COG1799	cell septum assembly
CEP64_RS07625	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CEP64_RS07630	COG1496	oxidoreductase activity
CEP64_RS07635	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CEP64_RS07640	COG0849	cell division
CEP64_RS07645	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
CEP64_RS07650	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CEP64_RS07655	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CEP64_RS07660	COG0768	penicillin binding
CEP64_RS07665	COG4839	cell division protein FtsL
CEP64_RS07670	COG0275	rRNA processing
CEP64_RS07675	COG2001	Belongs to the MraZ family
CEP64_RS07680	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
CEP64_RS07685	COG0454	-acetyltransferase
CEP64_RS07695	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CEP64_RS07700	COG0366	Alpha amylase catalytic
CEP64_RS07740	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CEP64_RS07750	COG1846	Transcriptional regulator
CEP64_RS07755	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CEP64_RS07760	COG1053	succinate dehydrogenase
CEP64_RS07765	COG2009	succinate dehydrogenase
CEP64_RS07770	COG0322	excinuclease ABC activity
CEP64_RS07775	COG3118	belongs to the thioredoxin family
CEP64_RS07780	COG1024	Enoyl-CoA hydratase
CEP64_RS07790	COG1796	DNA polymerase
CEP64_RS07790	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
CEP64_RS07800	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
CEP64_RS07805	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CEP64_RS07810	COG0072	phenylalanine-tRNA ligase activity
CEP64_RS07810	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CEP64_RS07815	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CEP64_RS07820	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CEP64_RS07840	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CEP64_RS07845	COG0742	ribosomal rna small subunit methyltransferase
CEP64_RS07855	COG4471	UPF0298 protein
CEP64_RS07860	COG0584	glycerophosphoryl diester phosphodiesterase
CEP64_RS07865	COG3679	Belongs to the UPF0342 family
CEP64_RS07870	COG2340	Cysteine-rich secretory protein family
CEP64_RS07880	COG0628	permease
CEP64_RS07890	COG3336	cytochrome c oxidase
CEP64_RS07915	COG0109	protoheme IX farnesyltransferase activity
CEP64_RS07920	COG1612	heme a metabolic process
CEP64_RS07930	COG0772	Belongs to the SEDS family
CEP64_RS07935	COG4838	Belongs to the UPF0358 family
CEP64_RS07945	COG4896	Protein conserved in bacteria
CEP64_RS07955	COG1217	gtp-binding protein TYPA
CEP64_RS07965	COG0483	inositol monophosphate 1-phosphatase activity
CEP64_RS07985	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CEP64_RS07990	COG1177	transmembrane transport
CEP64_RS07995	COG1176	ABC-type spermidine putrescine transport system, permease component I
CEP64_RS08000	COG3842	ATPase activity
CEP64_RS08010	COG4476	Belongs to the UPF0223 family
CEP64_RS08030	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CEP64_RS08040	COG0242	peptide deformylase activity
CEP64_RS08050	COG0561	phosphatase activity
CEP64_RS08055	COG5503	Protein of unknown function (DUF1447)
CEP64_RS08065	COG0569	domain protein
CEP64_RS08075	COG1271	oxidase subunit
CEP64_RS08085	COG1408	metallophosphoesterase
CEP64_RS08105	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CEP64_RS08115	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
CEP64_RS08130	COG1122	ATPase activity
CEP64_RS08140	COG0151	Belongs to the GarS family
CEP64_RS08145	COG0138	bifunctional purine biosynthesis protein purh
CEP64_RS08155	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
CEP64_RS08170	COG0047	phosphoribosylformylglycinamidine synthase activity
CEP64_RS08175	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CEP64_RS08180	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
CEP64_RS08190	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CEP64_RS08225	COG3964	amidohydrolase
CEP64_RS08230	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CEP64_RS08230	COG1017	nitric oxide dioxygenase activity
CEP64_RS08235	COG1959	2 iron, 2 sulfur cluster binding
CEP64_RS08245	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CEP64_RS08250	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CEP64_RS08255	COG1845	cytochrome c oxidase, subunit III
CEP64_RS08260	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
CEP64_RS08285	COG1134	teichoic acid transport
CEP64_RS08295	COG1682	transport, permease protein
CEP64_RS08315	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CEP64_RS08330	COG0463	Glycosyl transferase, family 2
CEP64_RS08330	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
CEP64_RS08340	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
CEP64_RS08345	COG0463	Glycosyl transferase, family 2
CEP64_RS08345	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
CEP64_RS08350	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
CEP64_RS08365	COG1215	transferase activity, transferring glycosyl groups
CEP64_RS08370	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
CEP64_RS08375	COG1682	transport, permease protein
CEP64_RS08380	COG1134	teichoic acid transport
CEP64_RS08400	COG0183	Belongs to the thiolase family
CEP64_RS08405	COG0318	PFAM AMP-dependent synthetase and ligase
CEP64_RS08410	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
CEP64_RS08415	COG1316	TRANSCRIPTIONal
CEP64_RS08435	COG3594	Acyltransferase
CEP64_RS08445	COG0436	Aminotransferase
CEP64_RS08450	COG4187	Peptidase family M20/M25/M40
CEP64_RS08455	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
CEP64_RS08460	COG0596	Alpha beta hydrolase
CEP64_RS08470	COG1169	isochorismate synthase
CEP64_RS08475	COG1575	Belongs to the MenA family. Type 1 subfamily
CEP64_RS08565	COG4873	Protein conserved in bacteria
CEP64_RS08575	COG0737	Belongs to the 5'-nucleotidase family
CEP64_RS08580	COG3852	Histidine kinase
CEP64_RS08585	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CEP64_RS08590	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CEP64_RS08590	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CEP64_RS08595	COG0861	Integral membrane protein TerC family
CEP64_RS08600	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
CEP64_RS08610	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CEP64_RS08630	COG2814	Major facilitator Superfamily
CEP64_RS08635	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
CEP64_RS08640	COG2382	esterase
CEP64_RS08645	COG1115	amino acid carrier protein
CEP64_RS08650	COG0628	permease
CEP64_RS08660	COG0569	domain protein
CEP64_RS08660	COG0475	glutathione-regulated potassium exporter activity
CEP64_RS08665	COG2239	Acts as a magnesium transporter
CEP64_RS08670	COG0564	pseudouridine synthase activity
CEP64_RS08680	COG2357	RelA SpoT domain protein
CEP64_RS08690	COG4116	CYTH
CEP64_RS08695	COG2346	COG2346, Truncated hemoglobins
CEP64_RS08700	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
CEP64_RS08705	COG1164	Oligoendopeptidase f
CEP64_RS08715	COG4862	establishment of competence for transformation
CEP64_RS08720	COG1393	Belongs to the ArsC family
CEP64_RS08730	COG4166	transmembrane transport
CEP64_RS08735	COG4166	transmembrane transport
CEP64_RS08740	COG4166	transmembrane transport
CEP64_RS08745	COG4166	transmembrane transport
CEP64_RS08750	COG4608	Belongs to the ABC transporter superfamily
CEP64_RS08755	COG0444	Belongs to the ABC transporter superfamily
CEP64_RS08760	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CEP64_RS08765	COG0601	transmembrane transport
CEP64_RS08790	COG0542	response to heat
CEP64_RS08795	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CEP64_RS08805	COG2151	metal-sulfur cluster biosynthetic enzyme
CEP64_RS08810	COG0561	phosphatase activity
CEP64_RS08815	COG1307	EDD domain protein, DegV family
CEP64_RS08825	COG1874	Beta-galactosidase
CEP64_RS08825	COG0366	Alpha amylase catalytic
CEP64_RS08835	COG0179	Fumarylacetoacetate (FAA) hydrolase
CEP64_RS08840	COG2311	Membrane
CEP64_RS08850	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
CEP64_RS08865	COG0398	Pfam SNARE associated Golgi protein
CEP64_RS08880	COG0137	argininosuccinate synthase activity
CEP64_RS08885	COG0165	Argininosuccinate lyase
CEP64_RS08895	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CEP64_RS08900	COG1012	belongs to the aldehyde dehydrogenase family
CEP64_RS08905	COG1098	S1 RNA binding domain
CEP64_RS08915	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CEP64_RS08925	COG2111	Na H antiporter
CEP64_RS08925	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CEP64_RS08930	COG2111	Na H antiporter
CEP64_RS08945	COG1863	multisubunit Na H antiporter MnhE subunit
CEP64_RS08950	COG2212	antiporter activity
CEP64_RS08955	COG1320	monovalent cation:proton antiporter activity
CEP64_RS08960	COG1028	Short-chain dehydrogenase reductase Sdr
CEP64_RS08965	COG2050	protein possibly involved in aromatic compounds catabolism
CEP64_RS08970	COG2056	Na+-H+ antiporter family
CEP64_RS08975	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CEP64_RS08985	COG1252	NADH dehydrogenase
CEP64_RS08990	COG0316	Belongs to the HesB IscA family
CEP64_RS08995	COG4844	belongs to the
CEP64_RS09000	COG1252	NADH dehydrogenase
CEP64_RS09005	COG4837	Protein of unknown function (DUF1462)
CEP64_RS09010	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
CEP64_RS09015	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
CEP64_RS09020	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CEP64_RS09025	COG1696	Membrane protein involved in D-alanine export
CEP64_RS09040	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CEP64_RS09045	COG0647	UMP catabolic process
CEP64_RS09050	COG2445	Protein of unknown function DUF86
CEP64_RS09060	COG4470	Protein conserved in bacteria
CEP64_RS09065	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
CEP64_RS09070	COG0737	Belongs to the 5'-nucleotidase family
CEP64_RS09075	COG0730	response to heat
CEP64_RS09080	COG1801	Protein of unknown function DUF72
CEP64_RS09085	COG1136	(ABC) transporter
CEP64_RS09105	COG1388	LysM domain
CEP64_RS09105	COG0860	N-Acetylmuramoyl-L-alanine amidase
CEP64_RS09115	COG1395	domain, Protein
CEP64_RS09130	COG0800	Aldolase
CEP64_RS09135	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CEP64_RS09140	COG1028	Short-chain dehydrogenase reductase Sdr
CEP64_RS09145	COG1940	carbohydrate kinase activity
CEP64_RS09150	COG2814	Major facilitator Superfamily
CEP64_RS09160	COG0719	Fe-S assembly protein
CEP64_RS09165	COG0822	iron-sulfur transferase activity
CEP64_RS09170	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CEP64_RS09175	COG0719	Fe-S assembly protein
CEP64_RS09180	COG0396	ATPase activity
CEP64_RS09190	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CEP64_RS09195	COG1464	Belongs to the NlpA lipoprotein family
CEP64_RS09200	COG2011	ABC-type metal ion transport system permease component
CEP64_RS09205	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CEP64_RS09215	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
CEP64_RS09220	COG0509	glycine decarboxylation via glycine cleavage system
CEP64_RS09225	COG1393	Belongs to the ArsC family
CEP64_RS09230	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CEP64_RS09235	COG0778	Nitroreductase
CEP64_RS09235	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
CEP64_RS09240	COG0710	3-dehydroquinate dehydratase activity
CEP64_RS09255	COG3237	CsbD-like
CEP64_RS09260	COG0697	spore germination
CEP64_RS09265	COG1764	response to oxidative stress
CEP64_RS09290	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CEP64_RS09305	COG4166	transmembrane transport
CEP64_RS09320	COG0523	cobalamin synthesis protein
CEP64_RS09325	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CEP64_RS09380	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CEP64_RS09395	COG0477	Major facilitator Superfamily
CEP64_RS09410	COG0406	alpha-ribazole phosphatase activity
CEP64_RS09415	COG1525	nuclease
CEP64_RS09425	COG1280	lysine exporter protein (LysE YggA)
CEP64_RS09430	COG0477	Major facilitator Superfamily
CEP64_RS09450	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CEP64_RS09455	COG0730	response to heat
CEP64_RS09500	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
CEP64_RS09505	COG0557	exoribonuclease II activity
CEP64_RS09510	COG1647	Serine aminopeptidase, S33
CEP64_RS09515	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CEP64_RS09520	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CEP64_RS09525	COG0148	phosphopyruvate hydratase activity
CEP64_RS09535	COG0149	triose-phosphate isomerase activity
CEP64_RS09540	COG0126	phosphoglycerate kinase activity
CEP64_RS09560	COG0740	serine-type endopeptidase activity
CEP64_RS09565	COG1481	regulation of sporulation
CEP64_RS09570	COG0391	Required for morphogenesis under gluconeogenic growth conditions
CEP64_RS09575	COG1660	Displays ATPase and GTPase activities
CEP64_RS09590	COG0110	maltose O-acetyltransferase activity
CEP64_RS09595	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CEP64_RS09600	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
CEP64_RS09630	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CEP64_RS09635	COG3942	CHAP domain
CEP64_RS09640	COG2010	Cytochrome c
CEP64_RS09645	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
CEP64_RS09650	COG0653	protein targeting
CEP64_RS09655	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CEP64_RS09660	COG1040	competence protein
CEP64_RS09665	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
CEP64_RS09670	COG1307	EDD domain protein, DegV family
CEP64_RS09680	COG1739	Uncharacterized protein family UPF0029
CEP64_RS09685	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CEP64_RS09690	COG2199	diguanylate cyclase activity
CEP64_RS09695	COG2966	Psort location CytoplasmicMembrane, score
CEP64_RS09735	COG0812	UDP-N-acetylmuramate dehydrogenase activity
CEP64_RS09740	COG4607	ABC-type enterochelin transport system periplasmic component
CEP64_RS09745	COG4604	ABC transporter, ATP-binding protein
CEP64_RS09750	COG4605	iron ion homeostasis
CEP64_RS09755	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CEP64_RS09765	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CEP64_RS09770	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CEP64_RS09775	COG1780	Probably involved in ribonucleotide reductase function
CEP64_RS09785	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
CEP64_RS09790	COG3104	oligopeptide transport
CEP64_RS09795	COG3104	oligopeptide transport
CEP64_RS09800	COG4502	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
CEP64_RS09810	COG1174	glycine betaine transport
CEP64_RS09815	COG0517	IMP dehydrogenase activity
CEP64_RS09815	COG1125	glycine betaine transport
CEP64_RS09820	COG0514	ATP-dependent DNA helicase (RecQ)
CEP64_RS09825	COG0488	(ABC) transporter
CEP64_RS09835	COG1368	sulfuric ester hydrolase activity
CEP64_RS09840	COG1984	allophanate hydrolase subunit 2
CEP64_RS09860	COG0512	Glutamine amidotransferase of anthranilate synthase
CEP64_RS09870	COG0720	synthase
CEP64_RS09875	COG0602	queuosine metabolic process
CEP64_RS09885	COG1695	Transcriptional regulator
CEP64_RS09905	COG0656	L-ascorbic acid biosynthetic process
CEP64_RS09910	COG1187	pseudouridine synthase activity
CEP64_RS09915	COG2814	Major facilitator Superfamily
CEP64_RS09920	COG1253	flavin adenine dinucleotide binding
CEP64_RS09925	COG2267	carboxylic ester hydrolase activity
CEP64_RS09930	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CEP64_RS09930	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CEP64_RS09930	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CEP64_RS09935	COG1105	Belongs to the carbohydrate kinase PfkB family
CEP64_RS09940	COG1349	DNA-binding transcription factor activity
CEP64_RS09945	COG1473	amidohydrolase
CEP64_RS09950	COG4989	oxidoreductase activity
CEP64_RS09955	COG0523	cobalamin synthesis protein
CEP64_RS09965	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
CEP64_RS09970	COG4988	ABC transporter
CEP64_RS09975	COG1968	undecaprenyl-diphosphatase activity
CEP64_RS10000	COG1683	Conserved Protein
CEP64_RS10015	COG1012	belongs to the aldehyde dehydrogenase family
CEP64_RS10035	COG0025	NhaP-type Na H and K H
CEP64_RS10060	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CEP64_RS10065	COG0765	amino acid transport
CEP64_RS10070	COG0765	amino acid transport
CEP64_RS10075	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CEP64_RS10080	COG1126	abc transporter atp-binding protein
CEP64_RS10090	COG0778	Nitroreductase
CEP64_RS10095	COG1136	(ABC) transporter
CEP64_RS10100	COG0577	efflux transmembrane transporter activity
CEP64_RS10110	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
CEP64_RS10115	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CEP64_RS10130	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CEP64_RS10130	COG1263	PTS System
CEP64_RS10135	COG0010	Belongs to the arginase family
CEP64_RS10140	COG1914	H( )-stimulated, divalent metal cation uptake system
CEP64_RS10145	COG1660	Displays ATPase and GTPase activities
CEP64_RS10190	COG1846	Transcriptional regulator
CEP64_RS10195	COG2818	Glycosylase
CEP64_RS10205	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CEP64_RS10220	COG0667	Aldo Keto reductase
CEP64_RS10225	COG0492	ferredoxin-NADP+ reductase activity
CEP64_RS10230	COG2207	Transcriptional regulator
CEP64_RS10235	COG2271	Major facilitator Superfamily
CEP64_RS10240	COG3226	Transcriptional regulator
CEP64_RS10250	COG1253	flavin adenine dinucleotide binding
CEP64_RS10260	COG2197	response regulator
CEP64_RS10265	COG4585	Histidine kinase
CEP64_RS10270	COG0842	Transport permease protein
CEP64_RS10275	COG1131	(ABC) transporter
CEP64_RS10285	COG0672	)-iron permease
CEP64_RS10290	COG2837	iron assimilation
CEP64_RS10295	COG2822	iron ion transport
CEP64_RS10320	COG1132	(ABC) transporter
CEP64_RS10325	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CEP64_RS10325	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CEP64_RS10335	COG1447	Phosphotransferase system cellobiose-specific component IIA
CEP64_RS10340	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CEP64_RS10340	COG3711	transcriptional antiterminator
CEP64_RS10345	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CEP64_RS10350	COG2723	6-phospho-beta-galactosidase activity
CEP64_RS10360	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CEP64_RS10365	COG2264	protein methyltransferase activity
CEP64_RS10370	COG3443	Belongs to the bacterial solute-binding protein 9 family
CEP64_RS10370	COG0803	Belongs to the bacterial solute-binding protein 9 family
CEP64_RS10380	COG1136	(ABC) transporter
CEP64_RS10395	COG4607	ABC-type enterochelin transport system periplasmic component
CEP64_RS10410	COG2162	N-hydroxyarylamine O-acetyltransferase activity
CEP64_RS10420	COG0477	Major facilitator Superfamily
CEP64_RS10425	COG0477	Major facilitator Superfamily
CEP64_RS10435	COG3732	PTS system glucitol sorbitol-specific
CEP64_RS10440	COG3730	PTS system glucitol sorbitol-specific
CEP64_RS10450	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CEP64_RS10450	COG3711	transcriptional antiterminator
CEP64_RS10460	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CEP64_RS10465	COG0740	serine-type endopeptidase activity
CEP64_RS10495	COG0400	carboxylic ester hydrolase activity
CEP64_RS10500	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CEP64_RS10505	COG0346	lactoylglutathione lyase activity
CEP64_RS10510	COG1846	Transcriptional regulator
CEP64_RS10515	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CEP64_RS10520	COG0626	cystathionine gamma-synthase activity
CEP64_RS10530	COG4978	Transcriptional regulator
CEP64_RS10530	COG0789	Transcriptional regulator
CEP64_RS10545	COG1131	(ABC) transporter
CEP64_RS10550	COG2188	Transcriptional regulator
CEP64_RS10555	COG2819	hydrolase of the alpha beta superfamily
CEP64_RS10565	COG3173	Aminoglycoside phosphotransferase
CEP64_RS10580	COG0463	Glycosyl transferase, family 2
CEP64_RS10580	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
CEP64_RS10590	COG0438	transferase activity, transferring glycosyl groups
CEP64_RS10595	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CEP64_RS10605	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CEP64_RS10610	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CEP64_RS10620	COG1486	melibiose metabolic process
CEP64_RS10640	COG1028	Short-chain dehydrogenase reductase Sdr
CEP64_RS10645	COG4175	Glycine betaine
CEP64_RS10645	COG0517	IMP dehydrogenase activity
CEP64_RS10665	COG1388	LysM domain
CEP64_RS10670	COG2910	NAD(P)H-binding
CEP64_RS10675	COG1959	2 iron, 2 sulfur cluster binding
CEP64_RS10685	COG0438	transferase activity, transferring glycosyl groups
CEP64_RS10710	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
CEP64_RS10715	COG1902	pentaerythritol trinitrate reductase activity
CEP64_RS10720	COG3037	sugar-specific permease SgaT UlaA
CEP64_RS10730	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CEP64_RS10740	COG2723	6-phospho-beta-galactosidase activity
CEP64_RS10745	COG2723	6-phospho-beta-galactosidase activity
CEP64_RS10750	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CEP64_RS10750	COG1263	PTS System
CEP64_RS10750	COG2190	(PTS) system
CEP64_RS10755	COG3711	transcriptional antiterminator
CEP64_RS10760	COG3239	Fatty acid desaturase
CEP64_RS10770	COG1363	Peptidase, m42
CEP64_RS10780	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
CEP64_RS10785	COG2357	RelA SpoT domain protein
CEP64_RS10790	COG1486	melibiose metabolic process
CEP64_RS10795	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CEP64_RS10795	COG1263	PTS System
CEP64_RS10800	COG1737	Transcriptional regulator
CEP64_RS10805	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CEP64_RS10810	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CEP64_RS10815	COG1279	arginine transmembrane transporter activity
CEP64_RS10820	COG0191	fructose-bisphosphate aldolase activity
CEP64_RS10825	COG0673	inositol 2-dehydrogenase activity
CEP64_RS10830	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CEP64_RS10835	COG1082	Xylose isomerase domain protein TIM barrel
CEP64_RS10840	COG0673	inositol 2-dehydrogenase activity
CEP64_RS10845	COG3962	Belongs to the TPP enzyme family
CEP64_RS10850	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CEP64_RS10860	COG1012	belongs to the aldehyde dehydrogenase family
CEP64_RS10865	COG1349	DNA-binding transcription factor activity
CEP64_RS10875	COG0778	Nitroreductase
CEP64_RS10880	COG1309	transcriptional regulator
CEP64_RS10885	COG1263	PTS System
CEP64_RS10885	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CEP64_RS10890	COG2824	Alkylphosphonate utilization operon protein PhnA
CEP64_RS10905	COG1131	(ABC) transporter
CEP64_RS10915	COG3711	transcriptional antiterminator
CEP64_RS10915	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CEP64_RS10920	COG2723	6-phospho-beta-galactosidase activity
CEP64_RS10925	COG1447	Phosphotransferase system cellobiose-specific component IIA
CEP64_RS10930	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CEP64_RS10940	COG1113	amino acid transport
CEP64_RS10950	COG0402	S-adenosylhomocysteine deaminase activity
CEP64_RS10955	COG1012	belongs to the aldehyde dehydrogenase family
CEP64_RS10960	COG0531	amino acid
CEP64_RS10965	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CEP64_RS10970	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CEP64_RS11015	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CEP64_RS11020	COG1136	(ABC) transporter
CEP64_RS11025	COG0577	efflux transmembrane transporter activity
CEP64_RS11030	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CEP64_RS11035	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CEP64_RS11035	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CEP64_RS11040	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CEP64_RS11045	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CEP64_RS11055	COG3711	transcriptional antiterminator
CEP64_RS11060	COG1063	alcohol dehydrogenase
CEP64_RS11070	COG2271	Major facilitator Superfamily
CEP64_RS11075	COG1028	Short-chain dehydrogenase reductase Sdr
CEP64_RS11080	COG1312	Catalyzes the dehydration of D-mannonate
CEP64_RS11085	COG1063	alcohol dehydrogenase
CEP64_RS11090	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CEP64_RS11095	COG0800	Aldolase
CEP64_RS11100	COG1414	Transcriptional regulator
CEP64_RS11105	COG0583	DNA-binding transcription factor activity
CEP64_RS11120	COG4876	unkown
CEP64_RS11160	COG4607	ABC-type enterochelin transport system periplasmic component
CEP64_RS11165	COG2207	Transcriptional regulator
CEP64_RS11165	COG3708	Transcriptional regulator
CEP64_RS11175	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CEP64_RS11180	COG0456	acetyltransferase
CEP64_RS11185	COG0765	amino acid transport
CEP64_RS11190	COG1126	abc transporter atp-binding protein
CEP64_RS11195	COG2079	MmgE PrpD family protein
CEP64_RS11200	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CEP64_RS11205	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CEP64_RS11210	COG1263	PTS System
CEP64_RS11210	COG2190	(PTS) system
CEP64_RS11210	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CEP64_RS11215	COG4948	Mandelate Racemase Muconate Lactonizing
CEP64_RS11225	COG3711	transcriptional antiterminator
CEP64_RS11235	COG0246	Mannitol dehydrogenase
CEP64_RS11245	COG0596	Alpha beta hydrolase
CEP64_RS11270	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CEP64_RS11275	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CEP64_RS11280	COG0018	arginyl-trna synthetase
CEP64_RS11295	COG1078	dGTPase activity
CEP64_RS11310	COG1028	Short-chain dehydrogenase reductase Sdr
CEP64_RS11320	COG4844	belongs to the
CEP64_RS11325	COG0095	Lipoate-protein ligase
CEP64_RS11365	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CEP64_RS11375	COG2011	ABC-type metal ion transport system permease component
CEP64_RS11390	COG0786	glutamate:sodium symporter activity
CEP64_RS11395	COG0531	amino acid
CEP64_RS11400	COG2363	Small membrane protein
CEP64_RS11410	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CEP64_RS11425	COG0363	glucosamine-6-phosphate deaminase activity
CEP64_RS11430	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
CEP64_RS11435	COG2190	(PTS) system
CEP64_RS11435	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CEP64_RS11435	COG1263	PTS System
CEP64_RS11450	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CEP64_RS11455	COG1469	GTP cyclohydrolase I activity
CEP64_RS11465	COG0431	NADPH-dependent FMN reductase
CEP64_RS11470	COG0561	phosphatase activity
CEP64_RS11480	COG1428	Deoxynucleoside kinase
CEP64_RS11485	COG1428	Deoxynucleoside kinase
CEP64_RS11495	COG1388	LysM domain
CEP64_RS11500	COG2608	mercury ion transmembrane transporter activity
CEP64_RS11510	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CEP64_RS11515	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CEP64_RS11525	COG1473	amidohydrolase
CEP64_RS11530	COG1473	amidohydrolase
CEP64_RS11535	COG1473	amidohydrolase
CEP64_RS11540	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CEP64_RS11545	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CEP64_RS11550	COG0049	tRNA binding
CEP64_RS11555	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CEP64_RS11565	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CEP64_RS11570	COG0085	RNA polymerase activity
CEP64_RS11575	COG2813	Specifically methylates the guanine in position
CEP64_RS11580	COG0222	ribosome binding
CEP64_RS11585	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CEP64_RS11590	COG0081	regulation of translation
CEP64_RS11595	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CEP64_RS11610	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CEP64_RS11625	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CEP64_RS11630	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
CEP64_RS11635	COG0215	cysteine-tRNA ligase activity
CEP64_RS11660	COG4956	integral membrane protein (PIN domain superfamily)
CEP64_RS11665	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
CEP64_RS11670	COG0542	response to heat
CEP64_RS11675	COG3869	Catalyzes the specific phosphorylation of arginine residues in
CEP64_RS11680	COG3880	PFAM UvrB UvrC protein
CEP64_RS11685	COG4463	regulation of RNA biosynthetic process
CEP64_RS11690	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CEP64_RS11700	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
CEP64_RS11705	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CEP64_RS11710	COG1289	transmembrane transporter activity
CEP64_RS11800	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CEP64_RS11820	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
CEP64_RS11825	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CEP64_RS11840	COG1098	S1 RNA binding domain
CEP64_RS11850	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
CEP64_RS11855	COG3956	TIGRFAM MazG family protein
CEP64_RS11860	COG2244	polysaccharide biosynthetic process
CEP64_RS11865	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CEP64_RS11870	COG0193	aminoacyl-tRNA hydrolase activity
CEP64_RS11880	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CEP64_RS11885	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CEP64_RS11890	COG2088	sporulation resulting in formation of a cellular spore
CEP64_RS11895	COG0251	oxidation-reduction process
CEP64_RS11900	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CEP64_RS11905	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
CEP64_RS11910	COG4466	Protein conserved in bacteria
CEP64_RS11920	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
CEP64_RS11925	COG0084	hydrolase, TatD family'
CEP64_RS11930	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CEP64_RS11930	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CEP64_RS11935	COG2002	toxin-antitoxin pair type II binding
CEP64_RS11940	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CEP64_RS11945	COG2827	Endonuclease containing a URI domain
CEP64_RS11960	COG1774	PSP1 C-terminal conserved region
CEP64_RS11965	COG0470	DNA polymerase III
CEP64_RS11970	COG3870	Protein conserved in bacteria
CEP64_RS11980	COG1982	Orn Lys Arg decarboxylase major
CEP64_RS12005	COG4667	esterase of the alpha-beta hydrolase superfamily
CEP64_RS12015	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
CEP64_RS12020	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CEP64_RS12035	COG2188	Transcriptional regulator
CEP64_RS12040	COG0366	Alpha amylase catalytic
CEP64_RS12045	COG1263	PTS System
CEP64_RS12045	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CEP64_RS12055	COG0791	NLP P60 protein
CEP64_RS12060	COG4948	Mandelate Racemase Muconate Lactonizing
CEP64_RS12065	COG1619	proteins homologs of microcin C7 resistance protein MccF
CEP64_RS12075	COG0493	'glutamate synthase
CEP64_RS12080	COG0070	glutamate synthase
CEP64_RS12080	COG0069	glutamate synthase activity
CEP64_RS12080	COG0067	glutamate synthase
CEP64_RS12085	COG0583	DNA-binding transcription factor activity
CEP64_RS12090	COG2094	Belongs to the DNA glycosylase MPG family
CEP64_RS12105	COG0346	lactoylglutathione lyase activity
CEP64_RS12115	COG2814	Major facilitator Superfamily
CEP64_RS12125	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CEP64_RS12140	COG2076	Multidrug Resistance protein
CEP64_RS12145	COG2076	Multidrug Resistance protein
CEP64_RS12165	COG1695	Transcriptional regulator
CEP64_RS12195	COG0346	lactoylglutathione lyase activity
CEP64_RS12200	COG0400	carboxylic ester hydrolase activity
CEP64_RS12240	COG0519	Catalyzes the synthesis of GMP from XMP
CEP64_RS12240	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CEP64_RS12245	COG0516	GMP reductase activity
CEP64_RS12245	COG0517	IMP dehydrogenase activity
CEP64_RS12250	COG2233	PERMEase
CEP64_RS12255	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CEP64_RS12270	COG2070	2-Nitropropane dioxygenase
CEP64_RS12275	COG0778	Nitroreductase
CEP64_RS12280	COG0733	neurotransmitter:sodium symporter activity
CEP64_RS12290	COG0471	metal ion transport
CEP64_RS12305	COG0346	lactoylglutathione lyase activity
CEP64_RS12310	COG1072	(Pantothenic acid kinase))
CEP64_RS12320	COG0384	phenazine biosynthesis protein PhzF
CEP64_RS12375	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CEP64_RS12405	COG3645	SOS response
CEP64_RS12405	COG3646	Phage regulatory protein
CEP64_RS12420	COG0582	viral genome integration into host DNA
CEP64_RS12430	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CEP64_RS12440	COG0360	Binds together with S18 to 16S ribosomal RNA
CEP64_RS12450	COG0668	transmembrane transport
CEP64_RS12455	COG1475	DNA binding
CEP64_RS12460	COG0626	cystathionine gamma-synthase activity
CEP64_RS12465	COG0626	cystathionine gamma-synthase activity
CEP64_RS12470	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
CEP64_RS12470	COG0646	methionine synthase
CEP64_RS12475	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CEP64_RS12485	COG1966	Carbon starvation protein
CEP64_RS12490	COG1475	DNA binding
CEP64_RS12495	COG0357	Ribosomal RNA small subunit methyltransferase G
CEP64_RS12500	COG0445	tRNA wobble uridine modification
CEP64_RS12505	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
CEP64_RS12515	COG0594	ribonuclease P activity
CEP64_RS12525	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CEP64_RS12530	COG0592	DNA-directed DNA polymerase activity
CEP64_RS12540	COG4152	abc transporter atp-binding protein
CEP64_RS12545	COG1668	transmembrane transport
CEP64_RS12550	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CEP64_RS12555	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
CEP64_RS12560	COG2501	S4 domain
CEP64_RS12565	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CEP64_RS12575	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CEP64_RS12580	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CEP64_RS12590	COG2986	histidine ammonia-lyase
CEP64_RS12595	COG3314	Sporulation integral membrane protein YlbJ
CEP64_RS12605	COG1228	amidohydrolase
CEP64_RS12610	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CEP64_RS12630	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CEP64_RS12640	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
CEP64_RS12645	COG0359	binds to the 23S rRNA
CEP64_RS12650	COG0305	Participates in initiation and elongation during chromosome replication
CEP64_RS12655	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CEP64_RS12665	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CEP64_RS12685	COG5002	protein histidine kinase activity
CEP64_RS12700	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
CEP64_RS12705	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
CEP64_RS12710	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
CEP64_RS12715	COG4978	Transcriptional regulator
CEP64_RS12715	COG0789	Transcriptional regulator
CEP64_RS12735	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CEP64_RS12745	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CEP64_RS12750	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CEP64_RS12760	COG4221	oxidoreductase activity
CEP64_RS12765	COG0110	maltose O-acetyltransferase activity
CEP64_RS12770	COG0583	DNA-binding transcription factor activity
CEP64_RS12790	COG1028	Short-chain dehydrogenase reductase Sdr
CEP64_RS12795	COG0583	DNA-binding transcription factor activity
CEP64_RS12805	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CEP64_RS12825	COG1063	alcohol dehydrogenase
CEP64_RS12845	COG1595	DNA-templated transcription, initiation
CEP64_RS12870	COG0415	Belongs to the DNA photolyase family
CEP64_RS12880	COG1064	alcohol dehydrogenase
CEP64_RS12890	COG2814	Major facilitator Superfamily
CEP64_RS12905	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
CEP64_RS12910	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CEP64_RS12940	COG1609	Transcriptional regulator
CEP64_RS12950	COG0235	Class ii aldolase
CEP64_RS12955	COG2160	L-arabinose isomerase activity
CEP64_RS12970	COG0640	Transcriptional regulator
CEP64_RS12990	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CEP64_RS12995	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CEP64_RS13000	COG0454	-acetyltransferase
CEP64_RS13005	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CEP64_RS13010	COG0765	amino acid transport
CEP64_RS13015	COG0765	amino acid transport
CEP64_RS13020	COG1126	abc transporter atp-binding protein
CEP64_RS13050	COG1028	Short-chain dehydrogenase reductase Sdr
CEP64_RS13070	COG1129	ABC transporter
CEP64_RS13075	COG2375	cellular response to nickel ion
CEP64_RS13075	COG1132	(ABC) transporter
CEP64_RS13080	COG1132	(ABC) transporter
CEP64_RS13095	COG0717	Belongs to the dCTP deaminase family
CEP64_RS13110	COG2146	nitrite reductase [NAD(P)H] activity
CEP64_RS13115	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CEP64_RS13130	COG1288	antiporter activity
CEP64_RS13135	COG3711	transcriptional antiterminator
CEP64_RS13140	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CEP64_RS13140	COG1263	PTS System
CEP64_RS13145	COG2723	6-phospho-beta-galactosidase activity
CEP64_RS13185	COG0025	NhaP-type Na H and K H
CEP64_RS13190	COG2508	Transcriptional regulator
CEP64_RS13195	COG1953	Uracil, thiamine, allantoin
CEP64_RS13200	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CEP64_RS13205	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CEP64_RS13215	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CEP64_RS13220	COG3257	ureidoglycine aminohydrolase activity
CEP64_RS13225	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
CEP64_RS13230	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
CEP64_RS13235	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CEP64_RS13240	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CEP64_RS13255	COG2807	transmembrane transport
CEP64_RS13260	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
CEP64_RS13265	COG2204	response regulator
CEP64_RS13275	COG1454	alcohol dehydrogenase
CEP64_RS13280	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
CEP64_RS13290	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CEP64_RS13315	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CEP64_RS13355	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CEP64_RS13360	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CEP64_RS13370	COG1609	Transcriptional regulator
CEP64_RS13375	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CEP64_RS13380	COG2610	gluconate transmembrane transporter activity
CEP64_RS13425	COG3290	protein histidine kinase activity
CEP64_RS13430	COG4565	transcriptional regulatory protein
CEP64_RS13435	COG3493	citrate carrier protein
CEP64_RS13450	COG1473	amidohydrolase
CEP64_RS13455	COG1473	amidohydrolase
CEP64_RS13460	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
CEP64_RS13475	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CEP64_RS13480	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CEP64_RS13485	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CEP64_RS13490	COG0019	diaminopimelate decarboxylase activity
CEP64_RS13500	COG4264	IucA IucC family
CEP64_RS13505	COG4264	IucA IucC family
CEP64_RS13515	COG0477	Major facilitator Superfamily
CEP64_RS13525	COG0702	epimerase
CEP64_RS13545	COG0726	polysaccharide deacetylase
CEP64_RS13555	COG1114	Component of the transport system for branched-chain amino acids
CEP64_RS13565	COG0183	Belongs to the thiolase family
CEP64_RS13570	COG3425	synthase
CEP64_RS13575	COG0477	Major facilitator Superfamily
CEP64_RS13580	COG0584	glycerophosphoryl diester phosphodiesterase
CEP64_RS13590	COG2972	Histidine kinase
CEP64_RS13595	COG4753	response regulator
CEP64_RS13595	COG2207	Transcriptional regulator
CEP64_RS13610	COG1846	Transcriptional regulator
CEP64_RS13625	COG0531	amino acid
CEP64_RS13635	COG1028	Short-chain dehydrogenase reductase Sdr
CEP64_RS13640	COG1597	lipid kinase activity
CEP64_RS13645	COG0589	response to stress
CEP64_RS13655	COG1525	nuclease
CEP64_RS13690	COG3764	Sortase (surface protein transpeptidase)
CEP64_RS13750	COG3942	CHAP domain
CEP64_RS13750	COG1388	LysM domain
CEP64_RS13870	COG0679	Auxin Efflux Carrier
CEP64_RS13875	COG1012	belongs to the aldehyde dehydrogenase family
CEP64_RS13880	COG1733	regulation of RNA biosynthetic process
CEP64_RS13895	COG1192	Involved in chromosome partitioning
CEP64_RS13925	COG2076	Multidrug Resistance protein
CEP64_RS13940	COG1309	transcriptional regulator
CEP64_RS13945	COG1192	Involved in chromosome partitioning
CEP64_RS14020	COG1028	Short-chain dehydrogenase reductase Sdr
CEP64_RS14030	COG2814	Major facilitator Superfamily
CEP64_RS14055	COG0726	polysaccharide deacetylase