locus-tag	class	description
CEP64_RS11010	COG0157	Belongs to the NadC ModD family
CEP64_RS12660	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
CEP64_RS13590	COG1104	cysteine desulfurase activity
CEP64_RS13710	COG1827	regulation of RNA biosynthetic process
CEP64_RS14095	COG2318	DinB family
CEP64_RS14100	COG2851	Citrate transporter
CEP64_RS14115	COG1054	Belongs to the UPF0176 family
CEP64_RS14160	COG0083	homoserine kinase activity
CEP64_RS14165	COG3386	PFAM SMP-30 Gluconolaconase
CEP64_RS14170	COG1304	FMN binding
CEP64_RS14190	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CEP64_RS14195	COG1028	Short-chain dehydrogenase reductase Sdr
CEP64_RS14205	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CEP64_RS14205	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CEP64_RS14205	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CEP64_RS14210	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CEP64_RS14210	COG3711	transcriptional antiterminator
CEP64_RS14220	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CEP64_RS14235	COG0579	oxidoreductase
CEP64_RS14245	COG0318	PFAM AMP-dependent synthetase and ligase
CEP64_RS14250	COG1960	acyl-CoA dehydrogenase activity
CEP64_RS14255	COG1250	3-hydroxyacyl-CoA dehydrogenase
CEP64_RS14255	COG1024	Enoyl-CoA hydratase
CEP64_RS14260	COG0183	Belongs to the thiolase family
CEP64_RS14265	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CEP64_RS14270	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CEP64_RS14275	COG3002	Belongs to the UPF0753 family
CEP64_RS14280	COG0288	reversible hydration of carbon dioxide
CEP64_RS14285	COG5609	conserved protein (DUF2294)
CEP64_RS14290	COG1283	sodium-dependent phosphate transmembrane transporter activity
CEP64_RS14295	COG0673	inositol 2-dehydrogenase activity
CEP64_RS14305	COG0673	inositol 2-dehydrogenase activity
CEP64_RS14325	COG2226	methyltransferase
CEP64_RS14330	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
CEP64_RS14345	COG0733	neurotransmitter:sodium symporter activity
CEP64_RS14350	COG0583	DNA-binding transcription factor activity
CEP64_RS14355	COG1380	Effector of murein hydrolase LrgA
CEP64_RS14360	COG1346	cytolysis
CEP64_RS14370	COG0175	sulfate reduction
CEP64_RS14375	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
CEP64_RS14380	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CEP64_RS14400	COG0730	response to heat
CEP64_RS14405	COG2046	Belongs to the sulfate adenylyltransferase family
CEP64_RS14410	COG0529	Catalyzes the synthesis of activated sulfate
CEP64_RS14415	COG1510	regulation of RNA biosynthetic process
CEP64_RS14420	COG1012	belongs to the aldehyde dehydrogenase family
CEP64_RS14425	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
CEP64_RS14435	COG0659	secondary active sulfate transmembrane transporter activity
CEP64_RS14445	COG1621	beta-fructofuranosidase activity
CEP64_RS14465	COG1247	-acetyltransferase
CEP64_RS14475	COG0668	transmembrane transport
CEP64_RS14480	COG2851	Citrate transporter
CEP64_RS14485	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CEP64_RS14505	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CEP64_RS14510	COG1113	amino acid transport
CEP64_RS14515	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
CEP64_RS14520	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CEP64_RS14525	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CEP64_RS14535	COG0477	Major facilitator Superfamily
CEP64_RS14540	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CEP64_RS14560	COG2205	protein histidine kinase activity
CEP64_RS14565	COG0745	RESPONSE REGULATOR receiver
CEP64_RS14570	COG2311	Membrane
CEP64_RS14585	COG3961	Belongs to the TPP enzyme family
CEP64_RS14605	COG1063	alcohol dehydrogenase
CEP64_RS14610	COG1063	alcohol dehydrogenase
CEP64_RS14615	COG3775	system Galactitol-specific IIC component
CEP64_RS14620	COG3414	Phosphotransferase system galactitol-specific IIB component
CEP64_RS14635	COG0531	amino acid
CEP64_RS14645	COG1464	Belongs to the NlpA lipoprotein family
CEP64_RS14650	COG2271	Major facilitator Superfamily
CEP64_RS14675	COG0531	amino acid
CEP64_RS14680	COG2130	NADP-dependent
CEP64_RS14695	COG2188	Transcriptional regulator
CEP64_RS14700	COG2222	sugar isomerase
CEP64_RS14705	COG1105	Belongs to the carbohydrate kinase PfkB family
CEP64_RS14710	COG3684	Belongs to the aldolase LacD family
CEP64_RS14720	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CEP64_RS14725	COG3715	PTS system
CEP64_RS14730	COG3716	PTS system mannose fructose sorbose family IID component
CEP64_RS14750	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
CEP64_RS14760	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
CEP64_RS14780	COG1316	TRANSCRIPTIONal
CEP64_RS14790	COG3001	Fructosamine kinase
CEP64_RS14795	COG0662	Cupin 2, conserved barrel domain protein
CEP64_RS14800	COG2807	transmembrane transport
CEP64_RS14805	COG1113	amino acid transport
CEP64_RS14815	COG3620	sequence-specific DNA binding
CEP64_RS14835	COG0488	(ABC) transporter
CEP64_RS14855	COG2084	Dehydrogenase
CEP64_RS14865	COG2610	gluconate transmembrane transporter activity
CEP64_RS14880	COG4336	lyase activity
CEP64_RS14885	COG3275	phosphorelay sensor kinase activity
CEP64_RS14890	COG3279	Response regulator of the LytR AlgR family
CEP64_RS14895	COG1380	Effector of murein hydrolase LrgA
CEP64_RS14900	COG1346	cytolysis
CEP64_RS14910	COG3844	kynureninase activity
CEP64_RS14915	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
CEP64_RS14935	COG2188	Transcriptional regulator
CEP64_RS14940	COG2723	6-phospho-beta-galactosidase activity
CEP64_RS14955	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CEP64_RS14960	COG1280	lysine exporter protein (LysE YggA)
CEP64_RS14965	COG1132	(ABC) transporter
CEP64_RS14970	COG1132	(ABC) transporter
CEP64_RS14980	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
CEP64_RS14985	COG3189	MarR family transcriptional regulator
CEP64_RS14990	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CEP64_RS14995	COG2022	thiamine diphosphate biosynthetic process
CEP64_RS15005	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CEP64_RS15010	COG0352	thiamine-phosphate diphosphorylase activity
CEP64_RS15040	COG4509	Sortase family
CEP64_RS15060	COG3279	Response regulator of the LytR AlgR family
CEP64_RS15070	COG1733	regulation of RNA biosynthetic process
CEP64_RS15075	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
CEP64_RS15095	COG2271	Major facilitator Superfamily
CEP64_RS15100	COG1233	COG1233 Phytoene dehydrogenase and related
CEP64_RS15105	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CEP64_RS15110	COG1012	belongs to the aldehyde dehydrogenase family
CEP64_RS15125	COG1380	Effector of murein hydrolase LrgA
CEP64_RS15135	COG1278	Cold shock
CEP64_RS15145	COG0833	amino acid
CEP64_RS15150	COG2040	homocysteine
CEP64_RS15155	COG1012	belongs to the aldehyde dehydrogenase family
CEP64_RS15160	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CEP64_RS15170	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CEP64_RS15175	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
CEP64_RS15180	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CEP64_RS15210	COG0656	L-ascorbic acid biosynthetic process
CEP64_RS15215	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
CEP64_RS15220	COG3759	membrane
CEP64_RS15225	COG2409	Drug exporters of the RND superfamily
CEP64_RS15230	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
CEP64_RS15235	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CEP64_RS15235	COG1263	PTS System
CEP64_RS15240	COG1737	Transcriptional regulator
CEP64_RS15250	COG1316	TRANSCRIPTIONal
CEP64_RS15255	COG2207	Transcriptional regulator
CEP64_RS15275	COG0582	viral genome integration into host DNA
CEP64_RS15280	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CEP64_RS15280	COG2111	Na H antiporter
CEP64_RS15285	COG2111	Na H antiporter
CEP64_RS15290	COG1006	Multisubunit Na H antiporter MnhC subunit
CEP64_RS15300	COG1863	multisubunit Na H antiporter MnhE subunit
CEP64_RS15305	COG2212	antiporter activity
CEP64_RS15310	COG1320	monovalent cation:proton antiporter activity
CEP64_RS15320	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CEP64_RS15330	COG1321	iron dependent repressor
CEP64_RS15340	COG1686	Belongs to the peptidase S11 family
CEP64_RS15345	COG1132	(ABC) transporter
CEP64_RS15350	COG1620	l-lactate permease
CEP64_RS15355	COG0039	L-malate dehydrogenase activity
CEP64_RS15360	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CEP64_RS15365	COG1120	ATPase activity
CEP64_RS15370	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CEP64_RS15375	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CEP64_RS15390	COG1302	Protein conserved in bacteria
CEP64_RS15395	COG2814	Major facilitator Superfamily
CEP64_RS15400	COG3314	Sporulation integral membrane protein YlbJ
CEP64_RS15405	COG2329	Antibiotic biosynthesis monooxygenase
CEP64_RS15410	COG0300	oxidoreductase activity
CEP64_RS15425	COG2962	Rard protein
CEP64_RS15440	COG1988	membrane-bound metal-dependent
CEP64_RS15450	COG1272	protein, Hemolysin III
CEP64_RS15465	COG1574	metal-dependent hydrolase with the TIM-barrel fold
CEP64_RS15480	COG2814	Major facilitator Superfamily
CEP64_RS15485	COG0489	protein tyrosine kinase activity
CEP64_RS15490	COG2194	sulfuric ester hydrolase activity
CEP64_RS15555	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CEP64_RS15565	COG1937	Protein conserved in bacteria
CEP64_RS15570	COG2217	Heavy metal translocating P-type atpase
CEP64_RS15575	COG0586	Pfam SNARE associated Golgi protein
CEP64_RS15580	COG0456	acetyltransferase
CEP64_RS15585	COG2514	catechol 2,3-dioxygenase activity
CEP64_RS15590	COG1119	ATPase activity
CEP64_RS15595	COG0561	phosphatase activity
CEP64_RS15610	COG1388	LysM domain
CEP64_RS15610	COG3942	CHAP domain
CEP64_RS15615	COG0702	epimerase
CEP64_RS15635	COG0640	Transcriptional regulator
CEP64_RS15650	COG0477	Major facilitator Superfamily
CEP64_RS15670	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CEP64_RS15680	COG2205	protein histidine kinase activity
CEP64_RS15685	COG1136	(ABC) transporter
CEP64_RS15690	COG0577	efflux transmembrane transporter activity
CEP64_RS15695	COG1392	Phosphate transport regulator
CEP64_RS15700	COG0306	phosphate transporter
CEP64_RS15705	COG3942	CHAP domain
CEP64_RS15705	COG1388	LysM domain
CEP64_RS15710	COG0670	Belongs to the BI1 family
CEP64_RS15715	COG0217	transcriptional regulatory protein
CEP64_RS15725	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CEP64_RS15740	COG1566	PFAM secretion protein HlyD family protein
CEP64_RS15745	COG2814	Major facilitator Superfamily
CEP64_RS15760	COG0583	DNA-binding transcription factor activity
CEP64_RS15765	COG2258	MOSC domain
CEP64_RS15775	COG2839	Protein conserved in bacteria
CEP64_RS15785	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CEP64_RS15795	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CEP64_RS15800	COG1447	Phosphotransferase system cellobiose-specific component IIA
CEP64_RS15805	COG4221	oxidoreductase activity
CEP64_RS15810	COG0788	formyltetrahydrofolate deformylase activity
CEP64_RS15815	COG0598	Magnesium transport protein CorA
CEP64_RS15820	COG1940	carbohydrate kinase activity
CEP64_RS15835	COG0778	Nitroreductase
CEP64_RS15845	COG2814	Major facilitator Superfamily
CEP64_RS15850	COG1733	regulation of RNA biosynthetic process
CEP64_RS15855	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CEP64_RS15875	COG1757	Na H antiporter
CEP64_RS15880	COG0004	ammonium transporteR
CEP64_RS15885	COG1473	amidohydrolase
CEP64_RS15895	COG2814	Major facilitator Superfamily
CEP64_RS15900	COG0753	catalase activity
CEP64_RS15915	COG3048	D-serine ammonia-lyase activity
CEP64_RS15920	COG1966	Carbon starvation protein
CEP64_RS15925	COG3383	formate dehydrogenase (NAD+) activity
CEP64_RS15945	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CEP64_RS15955	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CEP64_RS15960	COG2011	ABC-type metal ion transport system permease component
CEP64_RS15965	COG1464	Belongs to the NlpA lipoprotein family
CEP64_RS15980	COG3942	CHAP domain
CEP64_RS15985	COG1757	Na H antiporter
CEP64_RS15990	COG3942	CHAP domain
CEP64_RS16050	COG1131	(ABC) transporter
CEP64_RS16055	COG1823	symporter activity
CEP64_RS16060	COG1960	acyl-CoA dehydrogenase activity
CEP64_RS16065	COG0697	spore germination
CEP64_RS16070	COG2832	Protein of unknown function (DUF454)
CEP64_RS16075	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CEP64_RS16080	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CEP64_RS16090	COG2186	Transcriptional regulator
CEP64_RS16095	COG2186	Transcriptional regulator
CEP64_RS16105	COG1268	BioY protein
CEP64_RS16115	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
CEP64_RS16120	COG3383	formate dehydrogenase (NAD+) activity
CEP64_RS16130	COG4149	molybdate abc transporter
CEP64_RS16135	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
CEP64_RS16140	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
CEP64_RS16145	COG1140	nitrate reductase beta subunit
CEP64_RS16150	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
CEP64_RS16155	COG2181	nitrate reductase activity
CEP64_RS16165	COG4585	Histidine kinase
CEP64_RS16170	COG2197	response regulator
CEP64_RS16175	COG2223	nitrite transmembrane transporter activity
CEP64_RS16180	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CEP64_RS16185	COG0521	Mo-molybdopterin cofactor biosynthetic process
CEP64_RS16190	COG0315	cyclic pyranopterin monophosphate synthase activity
CEP64_RS16195	COG0303	'Molybdopterin
CEP64_RS16200	COG1763	Mo-molybdopterin cofactor biosynthetic process
CEP64_RS16215	COG0746	molybdenum cofactor guanylyltransferase activity
CEP64_RS16220	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CEP64_RS16225	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CEP64_RS16230	COG2814	Major facilitator Superfamily
CEP64_RS16245	COG2348	transferase activity, transferring amino-acyl groups
CEP64_RS16250	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CEP64_RS16255	COG0436	Aminotransferase
CEP64_RS16270	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CEP64_RS16285	COG4975	Glucose uptake
CEP64_RS16300	COG2252	PERMEase
CEP64_RS16310	COG0051	transcription antitermination factor activity, RNA binding
CEP64_RS16315	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CEP64_RS16320	COG0088	Forms part of the polypeptide exit tunnel
CEP64_RS16325	COG0089	rRNA binding
CEP64_RS16330	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CEP64_RS16335	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CEP64_RS16340	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CEP64_RS16345	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CEP64_RS16350	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CEP64_RS16355	COG0255	Belongs to the universal ribosomal protein uL29 family
CEP64_RS16365	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CEP64_RS16370	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CEP64_RS16375	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CEP64_RS16380	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CEP64_RS16385	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CEP64_RS16390	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CEP64_RS16395	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CEP64_RS16400	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CEP64_RS16405	COG1841	ribosomal large subunit assembly
CEP64_RS16415	COG0201	protein transport
CEP64_RS16430	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CEP64_RS16435	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CEP64_RS16445	COG0202	RNA polymerase activity
CEP64_RS16450	COG0203	ribosomal protein L17
CEP64_RS16455	COG1122	ATPase activity
CEP64_RS16470	COG0101	tRNA pseudouridine synthase activity
CEP64_RS16475	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CEP64_RS16480	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CEP64_RS16485	COG1011	Hydrolase
CEP64_RS16495	COG3655	Transcriptional regulator
CEP64_RS16500	COG0346	lactoylglutathione lyase activity
CEP64_RS16520	COG0604	alcohol dehydrogenase
CEP64_RS16525	COG1511	domain protein
CEP64_RS16535	COG3842	ATPase activity
CEP64_RS16540	COG2182	Extracellular solute-binding protein
CEP64_RS16545	COG1175	transmembrane transport
CEP64_RS16550	COG3833	ABC-type maltose transport systems, permease component
CEP64_RS16555	COG1609	Transcriptional regulator
CEP64_RS16560	COG0366	Alpha amylase catalytic
CEP64_RS16565	COG2376	Dihydroxyacetone kinase
CEP64_RS16570	COG1461	Dihydroxyacetone kinase
CEP64_RS16575	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
CEP64_RS16580	COG2186	Transcriptional regulator
CEP64_RS16585	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
CEP64_RS16590	COG1482	cell wall glycoprotein biosynthetic process
CEP64_RS16600	COG3942	CHAP domain
CEP64_RS16600	COG1388	LysM domain
CEP64_RS16610	COG1115	amino acid carrier protein
CEP64_RS16620	COG1757	Na H antiporter
CEP64_RS16630	COG1609	Transcriptional regulator
CEP64_RS16635	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CEP64_RS16640	COG1869	D-ribose catabolic process
CEP64_RS16645	COG1129	ABC transporter
CEP64_RS16650	COG1172	Belongs to the binding-protein-dependent transport system permease family
CEP64_RS16655	COG1879	ABC-type sugar transport system periplasmic component
CEP64_RS16660	COG0783	Belongs to the Dps family
CEP64_RS16665	COG0277	FAD linked oxidase domain protein
CEP64_RS16670	COG0247	lactate metabolic process
CEP64_RS16675	COG0813	purine-nucleoside phosphorylase activity
CEP64_RS16680	COG2390	Transcriptional regulator
CEP64_RS16685	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
CEP64_RS16695	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
CEP64_RS16705	COG1854	S-ribosylhomocysteine lyase activity
CEP64_RS16710	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
CEP64_RS16710	COG0456	acetyltransferase
CEP64_RS16750	COG5146	pantothenate kinase activity
CEP64_RS16755	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CEP64_RS16760	COG4589	Belongs to the CDS family
CEP64_RS16785	COG3343	RNA polymerase activity
CEP64_RS16790	COG0504	CTP synthase activity
CEP64_RS16795	COG4821	SIS domain
CEP64_RS16805	COG0191	fructose-bisphosphate aldolase activity
CEP64_RS16810	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CEP64_RS16820	COG1012	belongs to the aldehyde dehydrogenase family
CEP64_RS16825	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CEP64_RS16830	COG0254	rRNA binding
CEP64_RS16835	COG1435	thymidine kinase activity
CEP64_RS16845	COG2890	protein-(glutamine-N5) methyltransferase activity
CEP64_RS16850	COG0009	L-threonylcarbamoyladenylate synthase
CEP64_RS16855	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CEP64_RS16860	COG0698	ribose 5-phosphate isomerase
CEP64_RS16865	COG4475	Protein of unknown function (DUF436)
CEP64_RS16870	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CEP64_RS16875	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CEP64_RS16880	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CEP64_RS16890	COG0356	it plays a direct role in the translocation of protons across the membrane
CEP64_RS16895	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CEP64_RS16900	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CEP64_RS16905	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CEP64_RS16910	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CEP64_RS16915	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CEP64_RS16920	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CEP64_RS16945	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CEP64_RS16955	COG0629	single-stranded DNA binding
CEP64_RS16960	COG1388	LysM domain
CEP64_RS16970	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
CEP64_RS16975	COG0352	thiamine-phosphate diphosphorylase activity
CEP64_RS16980	COG0706	membrane insertase activity
CEP64_RS16985	COG1418	mRNA catabolic process
CEP64_RS16990	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CEP64_RS17000	COG0772	Belongs to the SEDS family
CEP64_RS17005	COG1181	Belongs to the D-alanine--D-alanine ligase family
CEP64_RS17010	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CEP64_RS17020	COG0513	Belongs to the DEAD box helicase family
CEP64_RS17060	COG2208	phosphoserine phosphatase activity
CEP64_RS17075	COG1191	sigma factor activity
CEP64_RS17080	COG2183	response to ionizing radiation
CEP64_RS17085	COG3091	SprT-like family
CEP64_RS17115	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CEP64_RS17125	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CEP64_RS17130	COG0473	3-isopropylmalate dehydrogenase activity
CEP64_RS17135	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CEP64_RS17140	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
CEP64_RS17150	COG0028	Belongs to the TPP enzyme family
CEP64_RS17155	COG0129	dihydroxy-acid dehydratase activity
CEP64_RS17160	COG0802	atpase or kinase
CEP64_RS17165	COG1214	PFAM Peptidase M22, glycoprotease
CEP64_RS17170	COG0456	acetyltransferase
CEP64_RS17175	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CEP64_RS17185	COG0488	(ABC) transporter
CEP64_RS17190	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
CEP64_RS17195	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CEP64_RS17200	COG0805	protein transport
CEP64_RS17205	COG2391	methyltransferase activity
CEP64_RS17210	COG0425	Belongs to the sulfur carrier protein TusA family
CEP64_RS17215	COG1609	Transcriptional regulator
CEP64_RS17220	COG1621	beta-fructofuranosidase activity
CEP64_RS17250	COG0459	protein refolding
CEP64_RS17260	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CEP64_RS17280	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CEP64_RS17285	COG1131	(ABC) transporter
CEP64_RS17300	COG1131	(ABC) transporter
CEP64_RS17315	COG1473	amidohydrolase
CEP64_RS17320	COG1802	Transcriptional regulator
CEP64_RS17325	COG1070	Carbohydrate kinase
CEP64_RS17330	COG2610	gluconate transmembrane transporter activity
CEP64_RS17335	COG2223	nitrite transmembrane transporter activity
CEP64_RS17365	COG0385	Bile acid
CEP64_RS17405	COG4512	PFAM Accessory gene regulator B
CEP64_RS17410	COG2706	6-phosphogluconolactonase activity
CEP64_RS17420	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CEP64_RS17425	COG0390	transport system, permease component
CEP64_RS17430	COG1012	belongs to the aldehyde dehydrogenase family
CEP64_RS17435	COG0673	inositol 2-dehydrogenase activity
CEP64_RS17450	COG1227	inorganic diphosphatase activity
CEP64_RS17455	COG1335	isochorismatase
CEP64_RS17470	COG0077	Prephenate dehydratase
CEP64_RS17485	COG0107	imidazoleglycerol-phosphate synthase activity
CEP64_RS17490	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
CEP64_RS17495	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CEP64_RS17500	COG0131	Imidazoleglycerol-phosphate dehydratase
CEP64_RS17505	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CEP64_RS17510	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CEP64_RS17515	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
CEP64_RS17520	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
CEP64_RS17525	COG0477	Major facilitator Superfamily
CEP64_RS17530	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CEP64_RS17535	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CEP64_RS17540	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
CEP64_RS17550	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CEP64_RS17555	COG4496	protein, YerC YecD
CEP64_RS17560	COG1876	peptidase activity
CEP64_RS17565	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
CEP64_RS17570	COG0210	DNA helicase
CEP64_RS17575	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CEP64_RS17580	COG4851	CamS sex pheromone cAM373 precursor
CEP64_RS17585	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CEP64_RS17590	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CEP64_RS17600	COG0154	amidase activity
CEP64_RS17605	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CEP64_RS17610	COG0433	COG0433 Predicted ATPase
CEP64_RS17615	COG1597	lipid kinase activity
CEP64_RS17635	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CEP64_RS17650	COG1528	Iron-storage protein
CEP64_RS17665	COG4129	membrane
CEP64_RS17670	COG0024	Methionine aminopeptidase
CEP64_RS17690	COG2197	response regulator
CEP64_RS17695	COG0288	reversible hydration of carbon dioxide
CEP64_RS17700	COG1295	ribonuclease BN
CEP64_RS17715	COG4840	Belongs to the UPF0435 family
CEP64_RS17720	COG2309	aminopeptidase activity
CEP64_RS17730	COG1607	acyl-coa hydrolase
CEP64_RS17735	COG0535	radical SAM domain protein
CEP64_RS17740	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CEP64_RS17745	COG0693	protein deglycase activity
CEP64_RS17755	COG0028	Belongs to the TPP enzyme family
CEP64_RS17760	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CEP64_RS17765	COG2137	regulation of response to DNA damage stimulus
CEP64_RS17775	COG1134	teichoic acid transport
CEP64_RS17785	COG1988	membrane-bound metal-dependent
CEP64_RS17790	COG1194	a g-specific adenine glycosylase
CEP64_RS17795	COG3557	Belongs to the UPF0374 family
CEP64_RS17805	COG0069	glutamate synthase activity
CEP64_RS17810	COG4129	membrane
CEP64_RS17815	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
CEP64_RS17820	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CEP64_RS17825	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CEP64_RS17830	COG0735	belongs to the Fur family
CEP64_RS17980	COG1609	Transcriptional regulator
CEP64_RS18010	COG1904	glucuronate isomerase
CEP64_RS18015	COG1501	Belongs to the glycosyl hydrolase 31 family
CEP64_RS18025	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CEP64_RS18030	COG0765	amino acid transport
CEP64_RS18035	COG1126	abc transporter atp-binding protein
CEP64_RS18040	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CEP64_RS18045	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
CEP64_RS18050	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CEP64_RS18055	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CEP64_RS18060	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
CEP64_RS18065	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CEP64_RS18070	COG0363	glucosamine-6-phosphate deaminase activity
CEP64_RS18080	COG0114	fumarate hydratase activity
CEP64_RS18085	COG0248	Ppx GppA phosphatase
CEP64_RS18090	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
CEP64_RS18095	COG0564	pseudouridine synthase activity
CEP64_RS18100	COG3153	acetyltransferase
CEP64_RS18100	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CEP64_RS18105	COG4585	Histidine kinase
CEP64_RS18105	COG2203	Gaf domain
CEP64_RS18110	COG2197	response regulator
CEP64_RS18115	COG1301	dicarboxylic acid transport
CEP64_RS18125	COG4399	Belongs to the UPF0754 family
CEP64_RS18130	COG3679	Belongs to the UPF0342 family
CEP64_RS18135	COG0420	3'-5' exonuclease activity
CEP64_RS18145	COG3481	metal-dependent phosphohydrolase, HD sub domain
CEP64_RS18150	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CEP64_RS18160	COG1846	Transcriptional regulator
CEP64_RS18170	COG0537	adenosine 5'-monophosphoramidase activity
CEP64_RS18175	COG1131	(ABC) transporter
CEP64_RS18185	COG2329	Antibiotic biosynthesis monooxygenase
CEP64_RS18190	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
CEP64_RS18195	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
CEP64_RS18200	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
CEP64_RS18265	COG0697	spore germination
CEP64_RS18270	COG0456	acetyltransferase
CEP64_RS18280	COG2814	Major facilitator Superfamily
CEP64_RS18305	COG0494	nUDIX hydrolase
CEP64_RS18310	COG1506	peptidase
CEP64_RS18315	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
CEP64_RS18320	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CEP64_RS18330	COG1012	belongs to the aldehyde dehydrogenase family
CEP64_RS18335	COG0656	L-ascorbic acid biosynthetic process
CEP64_RS18340	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CEP64_RS18360	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CEP64_RS18365	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CEP64_RS18380	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CEP64_RS18405	COG1595	DNA-templated transcription, initiation
CEP64_RS18450	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CEP64_RS18450	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CEP64_RS18455	COG0307	riboflavin synthase, alpha
CEP64_RS18470	COG0506	proline dehydrogenase activity
CEP64_RS18485	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CEP64_RS18490	COG2267	carboxylic ester hydrolase activity
CEP64_RS18500	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
CEP64_RS18505	COG1242	4 iron, 4 sulfur cluster binding
CEP64_RS18510	COG2814	Major facilitator Superfamily
CEP64_RS18515	COG0495	leucyl-tRNA aminoacylation
CEP64_RS18520	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CEP64_RS18525	COG2081	HI0933 family
CEP64_RS18530	COG2244	polysaccharide biosynthetic process
CEP64_RS18535	COG1187	pseudouridine synthase activity
CEP64_RS18555	COG0510	thiamine kinase activity
CEP64_RS18560	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CEP64_RS18565	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CEP64_RS18570	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
CEP64_RS18580	COG1363	Peptidase, m42
CEP64_RS18585	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CEP64_RS18590	COG0765	amino acid transport
CEP64_RS18595	COG1126	abc transporter atp-binding protein
CEP64_RS18605	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CEP64_RS18610	COG4848	Belongs to the UPF0354 family
CEP64_RS18615	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CEP64_RS18620	COG1674	ftsk spoiiie
CEP64_RS18625	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CEP64_RS18630	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
CEP64_RS18635	COG4980	gas vesicle protein
CEP64_RS18640	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
CEP64_RS18640	COG1605	Chorismate mutase
CEP64_RS18645	COG1609	Transcriptional regulator
CEP64_RS18650	COG0123	including yeast histone deacetylase and acetoin utilization protein
CEP64_RS18655	COG0517	IMP dehydrogenase activity
CEP64_RS18660	COG0454	-acetyltransferase
CEP64_RS18665	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CEP64_RS18675	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CEP64_RS18680	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CEP64_RS18685	COG1704	LemA family
CEP64_RS18695	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CEP64_RS18700	COG0204	Acyl-transferase
CEP64_RS18715	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CEP64_RS18725	COG1764	response to oxidative stress
CEP64_RS18735	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CEP64_RS18740	COG1956	GAF domain-containing protein
CEP64_RS18745	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
CEP64_RS18750	COG1104	cysteine desulfurase activity
CEP64_RS18755	COG0301	tRNA thio-modification
CEP64_RS18765	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CEP64_RS18770	COG0616	signal peptide processing
CEP64_RS18775	COG1714	RDD family
CEP64_RS18780	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
CEP64_RS18785	COG0827	DNA restriction-modification system
CEP64_RS18790	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CEP64_RS18795	COG0589	response to stress
CEP64_RS18800	COG0686	Belongs to the AlaDH PNT family
CEP64_RS18810	COG3142	Participates in the control of copper homeostasis
CEP64_RS18815	COG0006	proline dipeptidase activity
CEP64_RS18820	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
CEP64_RS18825	COG4109	DRTGG domain
CEP64_RS18835	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
CEP64_RS18845	COG0281	malic enzyme
CEP64_RS18850	COG1725	Transcriptional regulator
CEP64_RS18855	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
CEP64_RS18860	COG0825	malonyl-CoA metabolic process
CEP64_RS18865	COG0205	6-phosphofructokinase activity
CEP64_RS18870	COG0469	pyruvate kinase activity
CEP64_RS18875	COG1113	amino acid transport
CEP64_RS18880	COG0372	Belongs to the citrate synthase family
CEP64_RS18885	COG0538	isocitrate dehydrogenase activity
CEP64_RS18895	COG0745	RESPONSE REGULATOR receiver
CEP64_RS18900	COG5002	protein histidine kinase activity
CEP64_RS18905	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CEP64_RS18905	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CEP64_RS18910	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CEP64_RS18915	COG0237	dephospho-CoA kinase activity
CEP64_RS18920	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CEP64_RS18930	COG3611	Membrane attachment protein
CEP64_RS18935	COG1484	DNA-dependent DNA replication
CEP64_RS18945	COG0833	amino acid
CEP64_RS18950	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CEP64_RS18955	COG0291	Belongs to the bacterial ribosomal protein bL35 family
CEP64_RS18960	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CEP64_RS18965	COG4112	unkown
CEP64_RS18975	COG0544	peptidyl-prolyl cis-trans isomerase activity
CEP64_RS18980	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CEP64_RS18985	COG0218	Necessary for normal cell division and for the maintenance of normal septation
CEP64_RS18990	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
CEP64_RS18995	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CEP64_RS19000	COG0181	hydroxymethylbilane synthase activity
CEP64_RS19015	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
CEP64_RS19030	COG0285	dihydrofolate synthase activity
CEP64_RS19035	COG1288	antiporter activity
CEP64_RS19045	COG2003	Belongs to the UPF0758 family
CEP64_RS19055	COG1132	(ABC) transporter
CEP64_RS19060	COG1132	(ABC) transporter
CEP64_RS19070	COG1792	Involved in formation and maintenance of cell shape
CEP64_RS19080	COG0261	This protein binds to 23S rRNA in the presence of protein L20
CEP64_RS19085	COG2868	ribosomal protein
CEP64_RS19090	COG0211	Belongs to the bacterial ribosomal protein bL27 family
CEP64_RS19100	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CEP64_RS19105	COG4492	Belongs to the UPF0735 family
CEP64_RS19110	COG0632	four-way junction helicase activity
CEP64_RS19115	COG2255	four-way junction helicase activity
CEP64_RS19125	COG0343	queuine tRNA-ribosyltransferase activity
CEP64_RS19130	COG1862	Preprotein translocase
CEP64_RS19135	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CEP64_RS19135	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CEP64_RS19140	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CEP64_RS19140	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
CEP64_RS19150	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CEP64_RS19160	COG0860	N-Acetylmuramoyl-L-alanine amidase
CEP64_RS19165	COG0124	histidyl-tRNA synthetase
CEP64_RS19170	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CEP64_RS19180	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CEP64_RS19185	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CEP64_RS19190	COG1959	2 iron, 2 sulfur cluster binding
CEP64_RS19200	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CEP64_RS19205	COG0488	(ABC) transporter
CEP64_RS19210	COG1104	cysteine desulfurase activity
CEP64_RS19215	COG0482	sulfurtransferase activity
CEP64_RS19225	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CEP64_RS19230	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CEP64_RS19235	COG4472	Bacterial protein of unknown function (DUF965)
CEP64_RS19240	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CEP64_RS19250	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CEP64_RS19255	COG4122	O-methyltransferase activity
CEP64_RS19260	COG0826	peptidase U32
CEP64_RS19265	COG0826	peptidase U32
CEP64_RS19270	COG0572	uridine kinase
CEP64_RS19275	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CEP64_RS19280	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
CEP64_RS19285	COG1984	allophanate hydrolase subunit 2
CEP64_RS19295	COG0439	Biotin carboxylase
CEP64_RS19305	COG1914	H( )-stimulated, divalent metal cation uptake system
CEP64_RS19310	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CEP64_RS19315	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
CEP64_RS19320	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
CEP64_RS19330	COG1534	Rna-binding protein
CEP64_RS19335	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CEP64_RS19340	COG1713	HD superfamily hydrolase involved in NAD metabolism
CEP64_RS19345	COG0799	negative regulation of ribosome biogenesis
CEP64_RS19350	COG2226	methyltransferase
CEP64_RS19355	COG1555	photosystem II stabilization
CEP64_RS19355	COG1596	polysaccharide export
CEP64_RS19360	COG2131	deaminase
CEP64_RS19365	COG2333	competence protein COMEC
CEP64_RS19365	COG0658	competence protein
CEP64_RS19375	COG1466	dna polymerase III delta subunit
CEP64_RS19380	COG0268	Binds directly to 16S ribosomal RNA
CEP64_RS19385	COG0481	GTPase activity
CEP64_RS19390	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CEP64_RS19400	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CEP64_RS19405	COG0443	Heat shock 70 kDa protein
CEP64_RS19415	COG2264	protein methyltransferase activity
CEP64_RS19420	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CEP64_RS19425	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CEP64_RS19430	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CEP64_RS19435	COG1030	water channel activity
CEP64_RS19440	COG4864	UPF0365 protein
CEP64_RS19455	COG1702	phosphate starvation-inducible protein PhoH
CEP64_RS19460	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CEP64_RS19465	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
CEP64_RS19470	COG0295	cytidine deaminase activity
CEP64_RS19480	COG1381	Involved in DNA repair and RecF pathway recombination
CEP64_RS19485	COG0423	glycine-tRNA ligase activity
CEP64_RS19490	COG0517	IMP dehydrogenase activity
CEP64_RS19495	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
CEP64_RS19500	COG0358	DNA primase activity
CEP64_RS19505	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CEP64_RS19510	COG2010	Cytochrome c
CEP64_RS19515	COG2384	SAM-dependent methyltransferase
CEP64_RS19520	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CEP64_RS19525	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
CEP64_RS19530	COG0513	Belongs to the DEAD box helicase family
CEP64_RS19535	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
CEP64_RS19540	COG1121	(ABC) transporter
CEP64_RS19545	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CEP64_RS19550	COG0735	belongs to the Fur family
CEP64_RS19555	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
CEP64_RS19560	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
CEP64_RS19570	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CEP64_RS19575	COG0768	penicillin binding
CEP64_RS19580	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CEP64_RS19585	COG0573	inorganic phosphate transmembrane transporter activity
CEP64_RS19590	COG0581	inorganic phosphate transmembrane transporter activity
CEP64_RS19595	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CEP64_RS19600	COG0704	Plays a role in the regulation of phosphate uptake
CEP64_RS19605	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CEP64_RS19610	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CEP64_RS19615	COG0457	Tetratricopeptide repeat
CEP64_RS19615	COG0705	Rhomboid family
CEP64_RS19620	COG4483	Protein conserved in bacteria
CEP64_RS19625	COG1940	carbohydrate kinase activity
CEP64_RS19630	COG0011	TIGRFAM Protein of
CEP64_RS19640	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CEP64_RS19650	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CEP64_RS19655	COG1459	type II secretion system
CEP64_RS19685	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CEP64_RS19690	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CEP64_RS19700	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CEP64_RS19705	COG0095	Lipoate-protein ligase
CEP64_RS19720	COG0006	proline dipeptidase activity
CEP64_RS19725	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CEP64_RS19730	COG0511	ligase activity, forming carbon-carbon bonds
CEP64_RS19735	COG0439	Biotin carboxylase
CEP64_RS19740	COG1302	Protein conserved in bacteria
CEP64_RS19765	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CEP64_RS19770	COG1438	arginine binding
CEP64_RS19775	COG0497	DNA recombination
CEP64_RS19790	COG0280	phosphate acetyltransferase
CEP64_RS19805	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CEP64_RS19810	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CEP64_RS19815	COG0022	dehydrogenase e1 component
CEP64_RS19820	COG0508	dehydrogenase complex catalyzes the overall conversion of
CEP64_RS19830	COG4129	membrane
CEP64_RS19835	COG2195	Cleaves the N-terminal amino acid of tripeptides
CEP64_RS19845	COG1917	Cupin 2, conserved barrel domain protein
CEP64_RS19845	COG2207	Transcriptional regulator
CEP64_RS19850	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CEP64_RS19855	COG1234	tRNA 3'-trailer cleavage
CEP64_RS19860	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CEP64_RS19870	COG0667	Aldo Keto reductase
CEP64_RS19880	COG0735	belongs to the Fur family
CEP64_RS19885	COG4974	Belongs to the 'phage' integrase family
CEP64_RS19890	COG1547	Domain of unknown function (DUF309)
CEP64_RS19895	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
CEP64_RS19900	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CEP64_RS19905	COG1187	pseudouridine synthase activity
CEP64_RS19910	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CEP64_RS19915	COG1333	cytochrome c biogenesis protein
CEP64_RS19920	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CEP64_RS19925	COG0745	RESPONSE REGULATOR receiver
CEP64_RS19930	COG5002	protein histidine kinase activity
CEP64_RS19940	COG1141	Ferredoxin
CEP64_RS19945	COG4955	Helix-turn-helix domain
CEP64_RS19950	COG0514	ATP-dependent DNA helicase (RecQ)
CEP64_RS19965	COG0492	ferredoxin-NADP+ reductase activity
CEP64_RS19970	COG0252	asparaginase activity
CEP64_RS19975	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
CEP64_RS19980	COG0539	negative regulation of cytoplasmic translation
CEP64_RS19985	COG1160	GTP binding
CEP64_RS19990	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CEP64_RS20015	COG2226	methyltransferase
CEP64_RS20020	COG0142	geranyltranstransferase activity
CEP64_RS20025	COG0105	UTP biosynthetic process
CEP64_RS20030	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CEP64_RS20035	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CEP64_RS20040	COG0457	Tetratricopeptide repeat
CEP64_RS20055	COG0723	plastoquinol--plastocyanin reductase activity
CEP64_RS20060	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
CEP64_RS20070	COG4347	Protein of unknown function (DUF1405)
CEP64_RS20075	COG2738	Putative neutral zinc metallopeptidase
CEP64_RS20080	COG1694	Mazg nucleotide pyrophosphohydrolase
CEP64_RS20085	COG0438	transferase activity, transferring glycosyl groups
CEP64_RS20090	COG0617	tRNA 3'-terminal CCA addition
CEP64_RS20100	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CEP64_RS20100	COG1199	ATP-dependent helicase activity
CEP64_RS20110	COG3935	DnaD domain protein
CEP64_RS20115	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CEP64_RS20125	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CEP64_RS20125	COG4499	WXG100 protein secretion system (Wss), protein YukC
CEP64_RS20130	COG3331	DNA recombination
CEP64_RS20140	COG4474	Belongs to the UPF0398 family
CEP64_RS20145	COG3599	regulation of cell shape
CEP64_RS20155	COG0116	Belongs to the methyltransferase superfamily
CEP64_RS20160	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CEP64_RS20170	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
CEP64_RS20175	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CEP64_RS20180	COG0328	RNA-DNA hybrid ribonuclease activity
CEP64_RS20195	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
CEP64_RS20205	COG1413	lyase activity
CEP64_RS20230	COG0204	Acyl-transferase
CEP64_RS20250	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CEP64_RS20255	COG2190	(PTS) system
CEP64_RS20260	COG4479	Belongs to the UPF0346 family
CEP64_RS20265	COG0793	Belongs to the peptidase S41A family
CEP64_RS20280	COG0671	phosphoesterase, PA-phosphatase related
CEP64_RS20290	COG5002	protein histidine kinase activity
CEP64_RS20295	COG0567	Dehydrogenase, E1 component
CEP64_RS20315	COG0714	Associated with various cellular activities
CEP64_RS20320	COG4548	von Willebrand factor, type A
CEP64_RS20325	COG1114	Component of the transport system for branched-chain amino acids
CEP64_RS20330	COG5505	Protein of unknown function (DUF819)
CEP64_RS20335	COG3853	Toxic anion resistance protein (TelA)
CEP64_RS20345	COG1254	Belongs to the acylphosphatase family
CEP64_RS20380	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
CEP64_RS20385	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CEP64_RS20390	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CEP64_RS20395	COG0527	aspartate kinase activity
CEP64_RS20400	COG0488	(ABC) transporter
CEP64_RS20405	COG2996	Protein conserved in bacteria
CEP64_RS20410	COG3711	transcriptional antiterminator
CEP64_RS20415	COG1447	Phosphotransferase system cellobiose-specific component IIA
CEP64_RS20420	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CEP64_RS20420	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CEP64_RS20425	COG2723	6-phospho-beta-galactosidase activity
CEP64_RS20430	COG3684	Belongs to the aldolase LacD family
CEP64_RS20435	COG1105	Belongs to the carbohydrate kinase PfkB family
CEP64_RS20450	COG1349	DNA-binding transcription factor activity
CEP64_RS20455	COG1164	Oligoendopeptidase f
CEP64_RS20470	COG0789	Transcriptional regulator
CEP64_RS20495	COG0159	tryptophan synthase activity
CEP64_RS20500	COG0133	tryptophan synthase activity
CEP64_RS20505	COG0135	phosphoribosylanthranilate isomerase activity
CEP64_RS20515	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CEP64_RS20520	COG0512	Glutamine amidotransferase of anthranilate synthase
CEP64_RS20525	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CEP64_RS20530	COG1363	Peptidase, m42
CEP64_RS20535	COG0287	Prephenate dehydrogenase
CEP64_RS20545	COG1476	TRANSCRIPTIONal
CEP64_RS20550	COG1757	Na H antiporter
CEP64_RS20555	COG1929	Belongs to the glycerate kinase type-1 family
CEP64_RS20565	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CEP64_RS20600	COG0586	Pfam SNARE associated Golgi protein
CEP64_RS20610	COG0628	permease
CEP64_RS20615	COG2190	(PTS) system
CEP64_RS20615	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CEP64_RS20615	COG1263	PTS System
CEP64_RS20620	COG3711	transcriptional antiterminator
CEP64_RS20630	COG1115	amino acid carrier protein
CEP64_RS20635	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CEP64_RS20645	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
CEP64_RS20650	COG4841	protein insertion into membrane
CEP64_RS20655	COG0824	Thioesterase
CEP64_RS20665	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CEP64_RS20670	COG1970	mechanosensitive ion channel activity
CEP64_RS20675	COG1999	signal sequence binding
CEP64_RS20695	COG4846	Membrane protein involved in cytochrome C biogenesis
CEP64_RS20700	COG0785	Cytochrome C biogenesis protein
CEP64_RS20705	COG3763	UPF0154 protein
CEP64_RS20715	COG4224	UPF0291 protein
CEP64_RS20725	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CEP64_RS20735	COG0516	GMP reductase activity
CEP64_RS20740	COG0803	Belongs to the bacterial solute-binding protein 9 family
CEP64_RS20745	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CEP64_RS20750	COG0833	amino acid
CEP64_RS20765	COG0561	phosphatase activity
CEP64_RS20770	COG0083	homoserine kinase activity
CEP64_RS20775	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
CEP64_RS20780	COG0460	homoserine dehydrogenase
CEP64_RS20785	COG0527	aspartate kinase activity
CEP64_RS20800	COG2084	Dehydrogenase
CEP64_RS20810	COG1597	lipid kinase activity
CEP64_RS20845	COG0110	maltose O-acetyltransferase activity
CEP64_RS20860	COG0789	Transcriptional regulator
CEP64_RS20865	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
CEP64_RS20870	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CEP64_RS20875	COG0386	Belongs to the glutathione peroxidase family
CEP64_RS20880	COG1923	regulation of RNA biosynthetic process
CEP64_RS20885	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CEP64_RS20890	COG2267	carboxylic ester hydrolase activity
CEP64_RS20895	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CEP64_RS20900	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CEP64_RS20905	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CEP64_RS20910	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
CEP64_RS20915	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CEP64_RS20920	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CEP64_RS20930	COG4550	Control of competence regulator ComK, YlbF/YmcA
CEP64_RS20935	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CEP64_RS20945	COG1132	(ABC) transporter
CEP64_RS20950	COG1132	(ABC) transporter
CEP64_RS20960	COG1013	pyruvate-flavodoxin oxidoreductase activity
CEP64_RS20965	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
CEP64_RS20965	COG0674	pyruvate-flavodoxin oxidoreductase activity
CEP64_RS20970	COG1692	metallophosphoesterase
CEP64_RS20980	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
CEP64_RS20980	COG0463	Glycosyl transferase, family 2
CEP64_RS21005	COG0500	methyltransferase
CEP64_RS21010	COG0561	phosphatase activity
CEP64_RS21015	COG1917	Cupin 2, conserved barrel domain protein
CEP64_RS21015	COG2207	Transcriptional regulator
CEP64_RS21020	COG0697	spore germination
CEP64_RS21055	COG0596	Alpha beta hydrolase
CEP64_RS21065	COG1215	transferase activity, transferring glycosyl groups
CEP64_RS21070	COG3177	Filamentation induced by cAMP protein fic
CEP64_RS21075	COG1418	mRNA catabolic process
CEP64_RS21080	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CEP64_RS21085	COG1546	Belongs to the CinA family
CEP64_RS21085	COG1058	Belongs to the CinA family
CEP64_RS21105	COG0300	oxidoreductase activity
CEP64_RS21110	COG0612	Peptidase, M16
CEP64_RS21120	COG2188	Transcriptional regulator
CEP64_RS21130	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
CEP64_RS21135	COG0612	Peptidase, M16
CEP64_RS21140	COG1185	polyribonucleotide nucleotidyltransferase activity
CEP64_RS21150	COG0196	riboflavin kinase activity
CEP64_RS21155	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CEP64_RS21160	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CEP64_RS21165	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
CEP64_RS21170	COG1263	PTS System
CEP64_RS21170	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CEP64_RS21190	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CEP64_RS21195	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CEP64_RS21200	COG2169	Transcriptional regulator
CEP64_RS21210	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CEP64_RS21215	COG1358	cellular component organization or biogenesis
CEP64_RS21220	COG2740	Nucleic-acid-binding protein implicated in transcription termination
CEP64_RS21225	COG0195	Participates in both transcription termination and antitermination
CEP64_RS21230	COG0779	Required for maturation of 30S ribosomal subunits
CEP64_RS21235	COG2176	DNA-directed DNA polymerase activity
CEP64_RS21240	COG0442	prolyl-tRNA aminoacylation
CEP64_RS21250	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
CEP64_RS21255	COG4589	Belongs to the CDS family
CEP64_RS21265	COG0233	cytoplasmic translational termination
CEP64_RS21270	COG0528	UMP kinase activity
CEP64_RS21275	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CEP64_RS21280	COG0052	Belongs to the universal ribosomal protein uS2 family
CEP64_RS21290	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
CEP64_RS21295	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
CEP64_RS21300	COG4974	Belongs to the 'phage' integrase family
CEP64_RS21305	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
CEP64_RS21310	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CEP64_RS21315	COG0758	DNA mediated transformation
CEP64_RS21320	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CEP64_RS21325	COG0045	succinate-CoA ligase (ADP-forming) activity
CEP64_RS21330	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CEP64_RS21340	COG0463	Glycosyl transferase, family 2
CEP64_RS21345	COG4485	Bacterial membrane protein, YfhO
CEP64_RS21350	COG0335	large ribosomal subunit rRNA binding
CEP64_RS21355	COG0336	Belongs to the RNA methyltransferase TrmD family
CEP64_RS21365	COG1837	Belongs to the UPF0109 family
CEP64_RS21370	COG0228	four-way junction DNA binding
CEP64_RS21375	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CEP64_RS21380	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
CEP64_RS21385	COG0552	protein localization to endoplasmic reticulum
CEP64_RS21390	COG1196	nuclear chromosome segregation
CEP64_RS21410	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CEP64_RS21425	COG0416	fatty acid biosynthetic process
CEP64_RS21430	COG1349	DNA-binding transcription factor activity
CEP64_RS21435	COG3764	Sortase (surface protein transpeptidase)
CEP64_RS21440	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CEP64_RS21445	COG1760	l-serine dehydratase
CEP64_RS21450	COG1760	l-serine dehydratase
CEP64_RS21460	COG1302	Protein conserved in bacteria
CEP64_RS21465	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CEP64_RS21470	COG1564	THIamine pyrophosphokinase
CEP64_RS21475	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CEP64_RS21480	COG1162	GTPase activity
CEP64_RS21485	COG3850	Histidine kinase
CEP64_RS21485	COG5002	protein histidine kinase activity
CEP64_RS21490	COG0745	RESPONSE REGULATOR receiver
CEP64_RS21495	COG2124	cytochrome p450
CEP64_RS21515	COG0820	rRNA (adenine-C2-)-methyltransferase activity
CEP64_RS21520	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CEP64_RS21520	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CEP64_RS21525	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CEP64_RS21530	COG0242	peptide deformylase activity
CEP64_RS21545	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CEP64_RS21550	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CEP64_RS21555	COG1758	RNA polymerase activity
CEP64_RS21575	COG0471	metal ion transport
CEP64_RS21590	COG0284	orotidine-5'-phosphate decarboxylase activity
CEP64_RS21595	COG0167	dihydroorotate dehydrogenase activity
CEP64_RS21600	COG0543	2 iron, 2 sulfur cluster binding
CEP64_RS21605	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CEP64_RS21610	COG0505	Belongs to the CarA family
CEP64_RS21620	COG0540	Belongs to the ATCase OTCase family
CEP64_RS21630	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
CEP64_RS21635	COG0564	pseudouridine synthase activity
CEP64_RS21640	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CEP64_RS21655	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CEP64_RS21660	COG3599	regulation of cell shape
CEP64_RS21670	COG0762	integral membrane protein
CEP64_RS21675	COG1799	cell septum assembly
CEP64_RS21680	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CEP64_RS21685	COG1496	oxidoreductase activity
CEP64_RS21690	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CEP64_RS21695	COG0849	cell division
CEP64_RS21700	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
CEP64_RS21705	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CEP64_RS21710	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CEP64_RS21715	COG0768	penicillin binding
CEP64_RS21720	COG4839	cell division protein FtsL
CEP64_RS21725	COG0275	rRNA processing
CEP64_RS21730	COG2001	Belongs to the MraZ family
CEP64_RS21735	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
CEP64_RS21740	COG0454	-acetyltransferase
CEP64_RS21750	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CEP64_RS21755	COG0366	Alpha amylase catalytic
CEP64_RS21795	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CEP64_RS21805	COG1846	Transcriptional regulator
CEP64_RS21810	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CEP64_RS21815	COG1053	succinate dehydrogenase
CEP64_RS21820	COG2009	succinate dehydrogenase
CEP64_RS21825	COG0322	excinuclease ABC activity
CEP64_RS21830	COG3118	belongs to the thioredoxin family
CEP64_RS21835	COG1024	Enoyl-CoA hydratase
CEP64_RS21845	COG1796	DNA polymerase
CEP64_RS21845	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
CEP64_RS21855	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
CEP64_RS21860	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CEP64_RS21865	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CEP64_RS21865	COG0072	phenylalanine-tRNA ligase activity
CEP64_RS21870	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CEP64_RS21875	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CEP64_RS21895	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CEP64_RS21900	COG0742	ribosomal rna small subunit methyltransferase
CEP64_RS21910	COG4471	UPF0298 protein
CEP64_RS21915	COG0584	glycerophosphoryl diester phosphodiesterase
CEP64_RS21920	COG3679	Belongs to the UPF0342 family
CEP64_RS21925	COG2340	Cysteine-rich secretory protein family
CEP64_RS21935	COG0628	permease
CEP64_RS21945	COG3336	cytochrome c oxidase
CEP64_RS21970	COG0109	protoheme IX farnesyltransferase activity
CEP64_RS21975	COG1612	heme a metabolic process
CEP64_RS21985	COG0772	Belongs to the SEDS family
CEP64_RS21990	COG4838	Belongs to the UPF0358 family
CEP64_RS22000	COG4896	Protein conserved in bacteria
CEP64_RS22010	COG1217	gtp-binding protein TYPA
CEP64_RS22020	COG0483	inositol monophosphate 1-phosphatase activity
CEP64_RS22040	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CEP64_RS22045	COG1177	transmembrane transport
CEP64_RS22050	COG1176	ABC-type spermidine putrescine transport system, permease component I
CEP64_RS22055	COG3842	ATPase activity
CEP64_RS22065	COG4476	Belongs to the UPF0223 family
CEP64_RS22085	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CEP64_RS22095	COG0242	peptide deformylase activity
CEP64_RS22105	COG0561	phosphatase activity
CEP64_RS22110	COG5503	Protein of unknown function (DUF1447)
CEP64_RS22120	COG0569	domain protein
CEP64_RS22130	COG1271	oxidase subunit
CEP64_RS22140	COG1408	metallophosphoesterase
CEP64_RS22160	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CEP64_RS22170	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
CEP64_RS22185	COG1122	ATPase activity
CEP64_RS22195	COG0151	Belongs to the GarS family
CEP64_RS22200	COG0138	bifunctional purine biosynthesis protein purh
CEP64_RS22210	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
CEP64_RS22225	COG0047	phosphoribosylformylglycinamidine synthase activity
CEP64_RS22230	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CEP64_RS22235	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
CEP64_RS22245	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CEP64_RS22280	COG3964	amidohydrolase
CEP64_RS22285	COG1017	nitric oxide dioxygenase activity
CEP64_RS22285	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CEP64_RS22290	COG1959	2 iron, 2 sulfur cluster binding
CEP64_RS22300	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CEP64_RS22305	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CEP64_RS22310	COG1845	cytochrome c oxidase, subunit III
CEP64_RS22315	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
CEP64_RS22340	COG1134	teichoic acid transport
CEP64_RS22350	COG1682	transport, permease protein
CEP64_RS22370	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CEP64_RS22385	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
CEP64_RS22385	COG0463	Glycosyl transferase, family 2
CEP64_RS22395	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
CEP64_RS22400	COG0463	Glycosyl transferase, family 2
CEP64_RS22400	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
CEP64_RS22405	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
CEP64_RS22420	COG1215	transferase activity, transferring glycosyl groups
CEP64_RS22425	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
CEP64_RS22430	COG1682	transport, permease protein
CEP64_RS22435	COG1134	teichoic acid transport
CEP64_RS22455	COG0183	Belongs to the thiolase family
CEP64_RS22460	COG0318	PFAM AMP-dependent synthetase and ligase
CEP64_RS22465	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
CEP64_RS22470	COG1316	TRANSCRIPTIONal
CEP64_RS22490	COG3594	Acyltransferase
CEP64_RS22500	COG0436	Aminotransferase
CEP64_RS22505	COG4187	Peptidase family M20/M25/M40
CEP64_RS22510	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
CEP64_RS22515	COG0596	Alpha beta hydrolase
CEP64_RS22525	COG1169	isochorismate synthase
CEP64_RS22530	COG1575	Belongs to the MenA family. Type 1 subfamily
CEP64_RS22620	COG4873	Protein conserved in bacteria
CEP64_RS22630	COG0737	Belongs to the 5'-nucleotidase family
CEP64_RS22635	COG3852	Histidine kinase
CEP64_RS22640	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CEP64_RS22645	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CEP64_RS22645	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CEP64_RS22650	COG0861	Integral membrane protein TerC family
CEP64_RS22655	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
CEP64_RS22665	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CEP64_RS22685	COG2814	Major facilitator Superfamily
CEP64_RS22690	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
CEP64_RS22695	COG2382	esterase
CEP64_RS22700	COG1115	amino acid carrier protein
CEP64_RS22705	COG0628	permease
CEP64_RS22715	COG0569	domain protein
CEP64_RS22715	COG0475	glutathione-regulated potassium exporter activity
CEP64_RS22720	COG2239	Acts as a magnesium transporter
CEP64_RS22725	COG0564	pseudouridine synthase activity
CEP64_RS22735	COG2357	RelA SpoT domain protein
CEP64_RS22745	COG4116	CYTH
CEP64_RS22750	COG2346	COG2346, Truncated hemoglobins
CEP64_RS22755	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
CEP64_RS22760	COG1164	Oligoendopeptidase f
CEP64_RS22770	COG4862	establishment of competence for transformation
CEP64_RS22775	COG1393	Belongs to the ArsC family
CEP64_RS22785	COG4166	transmembrane transport
CEP64_RS22790	COG4166	transmembrane transport
CEP64_RS22795	COG4166	transmembrane transport
CEP64_RS22800	COG4166	transmembrane transport
CEP64_RS22805	COG4608	Belongs to the ABC transporter superfamily
CEP64_RS22810	COG0444	Belongs to the ABC transporter superfamily
CEP64_RS22815	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CEP64_RS22820	COG0601	transmembrane transport
CEP64_RS22845	COG0542	response to heat
CEP64_RS22850	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CEP64_RS22860	COG2151	metal-sulfur cluster biosynthetic enzyme
CEP64_RS22865	COG0561	phosphatase activity
CEP64_RS22870	COG1307	EDD domain protein, DegV family
CEP64_RS22880	COG0366	Alpha amylase catalytic
CEP64_RS22880	COG1874	Beta-galactosidase
CEP64_RS22890	COG0179	Fumarylacetoacetate (FAA) hydrolase
CEP64_RS22895	COG2311	Membrane
CEP64_RS22905	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
CEP64_RS22920	COG0398	Pfam SNARE associated Golgi protein
CEP64_RS22935	COG0137	argininosuccinate synthase activity
CEP64_RS22940	COG0165	Argininosuccinate lyase
CEP64_RS22950	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CEP64_RS22955	COG1012	belongs to the aldehyde dehydrogenase family
CEP64_RS22960	COG1098	S1 RNA binding domain
CEP64_RS22970	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CEP64_RS22980	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CEP64_RS22980	COG2111	Na H antiporter
CEP64_RS22985	COG2111	Na H antiporter
CEP64_RS23000	COG1863	multisubunit Na H antiporter MnhE subunit
CEP64_RS23005	COG2212	antiporter activity
CEP64_RS23010	COG1320	monovalent cation:proton antiporter activity
CEP64_RS23015	COG1028	Short-chain dehydrogenase reductase Sdr
CEP64_RS23020	COG2050	protein possibly involved in aromatic compounds catabolism
CEP64_RS23025	COG2056	Na+-H+ antiporter family
CEP64_RS23030	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CEP64_RS23040	COG1252	NADH dehydrogenase
CEP64_RS23045	COG0316	Belongs to the HesB IscA family
CEP64_RS23050	COG4844	belongs to the
CEP64_RS23055	COG1252	NADH dehydrogenase
CEP64_RS23060	COG4837	Protein of unknown function (DUF1462)
CEP64_RS23065	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
CEP64_RS23070	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
CEP64_RS23075	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CEP64_RS23080	COG1696	Membrane protein involved in D-alanine export
CEP64_RS23095	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CEP64_RS23100	COG0647	UMP catabolic process
CEP64_RS23105	COG2445	Protein of unknown function DUF86
CEP64_RS23115	COG4470	Protein conserved in bacteria
CEP64_RS23120	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
CEP64_RS23125	COG0737	Belongs to the 5'-nucleotidase family
CEP64_RS23130	COG0730	response to heat
CEP64_RS23135	COG1801	Protein of unknown function DUF72
CEP64_RS23140	COG1136	(ABC) transporter
CEP64_RS23160	COG0860	N-Acetylmuramoyl-L-alanine amidase
CEP64_RS23160	COG1388	LysM domain
CEP64_RS23170	COG1395	domain, Protein
CEP64_RS23185	COG0800	Aldolase
CEP64_RS23190	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CEP64_RS23195	COG1028	Short-chain dehydrogenase reductase Sdr
CEP64_RS23200	COG1940	carbohydrate kinase activity
CEP64_RS23205	COG2814	Major facilitator Superfamily
CEP64_RS23215	COG0719	Fe-S assembly protein
CEP64_RS23220	COG0822	iron-sulfur transferase activity
CEP64_RS23225	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CEP64_RS23230	COG0719	Fe-S assembly protein
CEP64_RS23235	COG0396	ATPase activity
CEP64_RS23245	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CEP64_RS23250	COG1464	Belongs to the NlpA lipoprotein family
CEP64_RS23255	COG2011	ABC-type metal ion transport system permease component
CEP64_RS23260	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CEP64_RS23270	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
CEP64_RS23275	COG0509	glycine decarboxylation via glycine cleavage system
CEP64_RS23280	COG1393	Belongs to the ArsC family
CEP64_RS23285	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CEP64_RS23290	COG0778	Nitroreductase
CEP64_RS23290	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
CEP64_RS23295	COG0710	3-dehydroquinate dehydratase activity
CEP64_RS23310	COG3237	CsbD-like
CEP64_RS23315	COG0697	spore germination
CEP64_RS23320	COG1764	response to oxidative stress
CEP64_RS23345	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CEP64_RS23360	COG4166	transmembrane transport
CEP64_RS23375	COG0523	cobalamin synthesis protein
CEP64_RS23380	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CEP64_RS23435	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CEP64_RS23450	COG0477	Major facilitator Superfamily
CEP64_RS23465	COG0406	alpha-ribazole phosphatase activity
CEP64_RS23470	COG1525	nuclease
CEP64_RS23480	COG1280	lysine exporter protein (LysE YggA)
CEP64_RS23485	COG0477	Major facilitator Superfamily
CEP64_RS23505	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CEP64_RS23510	COG0730	response to heat
CEP64_RS23555	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
CEP64_RS23560	COG0557	exoribonuclease II activity
CEP64_RS23565	COG1647	Serine aminopeptidase, S33
CEP64_RS23570	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CEP64_RS23575	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CEP64_RS23580	COG0148	phosphopyruvate hydratase activity
CEP64_RS23590	COG0149	triose-phosphate isomerase activity
CEP64_RS23595	COG0126	phosphoglycerate kinase activity
CEP64_RS23615	COG0740	serine-type endopeptidase activity
CEP64_RS23620	COG1481	regulation of sporulation
CEP64_RS23625	COG0391	Required for morphogenesis under gluconeogenic growth conditions
CEP64_RS23630	COG1660	Displays ATPase and GTPase activities
CEP64_RS23645	COG0110	maltose O-acetyltransferase activity
CEP64_RS23650	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CEP64_RS23655	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
CEP64_RS23685	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CEP64_RS23690	COG3942	CHAP domain
CEP64_RS23695	COG2010	Cytochrome c
CEP64_RS23705	COG0653	protein targeting
CEP64_RS23710	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CEP64_RS23715	COG1040	competence protein
CEP64_RS23720	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
CEP64_RS23725	COG1307	EDD domain protein, DegV family
CEP64_RS23735	COG1739	Uncharacterized protein family UPF0029
CEP64_RS23740	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CEP64_RS23745	COG2199	diguanylate cyclase activity
CEP64_RS23750	COG2966	Psort location CytoplasmicMembrane, score
CEP64_RS23790	COG0812	UDP-N-acetylmuramate dehydrogenase activity
CEP64_RS23795	COG4607	ABC-type enterochelin transport system periplasmic component
CEP64_RS23800	COG4604	ABC transporter, ATP-binding protein
CEP64_RS23805	COG4605	iron ion homeostasis
CEP64_RS23810	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CEP64_RS23820	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CEP64_RS23825	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CEP64_RS23830	COG1780	Probably involved in ribonucleotide reductase function
CEP64_RS23840	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
CEP64_RS23845	COG3104	oligopeptide transport
CEP64_RS23850	COG3104	oligopeptide transport
CEP64_RS23855	COG4502	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
CEP64_RS23865	COG1174	glycine betaine transport
CEP64_RS23870	COG0517	IMP dehydrogenase activity
CEP64_RS23870	COG1125	glycine betaine transport
CEP64_RS23875	COG0514	ATP-dependent DNA helicase (RecQ)
CEP64_RS23880	COG0488	(ABC) transporter
CEP64_RS23890	COG1368	sulfuric ester hydrolase activity
CEP64_RS23895	COG1984	allophanate hydrolase subunit 2
CEP64_RS23915	COG0512	Glutamine amidotransferase of anthranilate synthase
CEP64_RS23925	COG0720	synthase
CEP64_RS23930	COG0602	queuosine metabolic process
CEP64_RS23940	COG1695	Transcriptional regulator
CEP64_RS23960	COG0656	L-ascorbic acid biosynthetic process
CEP64_RS23965	COG1187	pseudouridine synthase activity
CEP64_RS23970	COG2814	Major facilitator Superfamily
CEP64_RS23975	COG1253	flavin adenine dinucleotide binding
CEP64_RS23980	COG2267	carboxylic ester hydrolase activity
CEP64_RS23985	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CEP64_RS23985	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CEP64_RS23985	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CEP64_RS23990	COG1105	Belongs to the carbohydrate kinase PfkB family
CEP64_RS23995	COG1349	DNA-binding transcription factor activity
CEP64_RS24000	COG1473	amidohydrolase
CEP64_RS24005	COG4989	oxidoreductase activity
CEP64_RS24010	COG0523	cobalamin synthesis protein
CEP64_RS24020	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
CEP64_RS24025	COG4988	ABC transporter
CEP64_RS24030	COG1968	undecaprenyl-diphosphatase activity
CEP64_RS24055	COG1683	Conserved Protein
CEP64_RS24070	COG1012	belongs to the aldehyde dehydrogenase family
CEP64_RS24090	COG0025	NhaP-type Na H and K H
CEP64_RS24115	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CEP64_RS24120	COG0765	amino acid transport
CEP64_RS24125	COG0765	amino acid transport
CEP64_RS24130	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CEP64_RS24135	COG1126	abc transporter atp-binding protein
CEP64_RS24145	COG0778	Nitroreductase
CEP64_RS24150	COG1136	(ABC) transporter
CEP64_RS24155	COG0577	efflux transmembrane transporter activity
CEP64_RS24165	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
CEP64_RS24170	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CEP64_RS24185	COG1263	PTS System
CEP64_RS24185	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CEP64_RS24190	COG0010	Belongs to the arginase family
CEP64_RS24195	COG1914	H( )-stimulated, divalent metal cation uptake system
CEP64_RS24200	COG1660	Displays ATPase and GTPase activities
CEP64_RS24245	COG1846	Transcriptional regulator
CEP64_RS24250	COG2818	Glycosylase
CEP64_RS24260	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CEP64_RS24275	COG0667	Aldo Keto reductase
CEP64_RS24280	COG0492	ferredoxin-NADP+ reductase activity
CEP64_RS24285	COG2207	Transcriptional regulator
CEP64_RS24290	COG2271	Major facilitator Superfamily
CEP64_RS24295	COG3226	Transcriptional regulator
CEP64_RS24305	COG1253	flavin adenine dinucleotide binding
CEP64_RS24315	COG2197	response regulator
CEP64_RS24320	COG4585	Histidine kinase
CEP64_RS24325	COG0842	Transport permease protein
CEP64_RS24330	COG1131	(ABC) transporter
CEP64_RS24340	COG0672	)-iron permease
CEP64_RS24345	COG2837	iron assimilation
CEP64_RS24350	COG2822	iron ion transport
CEP64_RS24375	COG1132	(ABC) transporter
CEP64_RS24380	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CEP64_RS24380	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CEP64_RS24390	COG1447	Phosphotransferase system cellobiose-specific component IIA
CEP64_RS24395	COG3711	transcriptional antiterminator
CEP64_RS24395	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CEP64_RS24400	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CEP64_RS24405	COG2723	6-phospho-beta-galactosidase activity
CEP64_RS24415	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CEP64_RS24420	COG2264	protein methyltransferase activity
CEP64_RS24425	COG3443	Belongs to the bacterial solute-binding protein 9 family
CEP64_RS24425	COG0803	Belongs to the bacterial solute-binding protein 9 family
CEP64_RS24435	COG1136	(ABC) transporter
CEP64_RS24450	COG4607	ABC-type enterochelin transport system periplasmic component
CEP64_RS24465	COG2162	N-hydroxyarylamine O-acetyltransferase activity
CEP64_RS24475	COG0477	Major facilitator Superfamily
CEP64_RS24480	COG0477	Major facilitator Superfamily
CEP64_RS24490	COG3732	PTS system glucitol sorbitol-specific
CEP64_RS24495	COG3730	PTS system glucitol sorbitol-specific
CEP64_RS24505	COG3711	transcriptional antiterminator
CEP64_RS24505	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CEP64_RS24515	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CEP64_RS24520	COG0740	serine-type endopeptidase activity
CEP64_RS24550	COG0400	carboxylic ester hydrolase activity
CEP64_RS24555	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CEP64_RS24560	COG0346	lactoylglutathione lyase activity
CEP64_RS24565	COG1846	Transcriptional regulator
CEP64_RS24570	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CEP64_RS24575	COG0626	cystathionine gamma-synthase activity
CEP64_RS24585	COG0789	Transcriptional regulator
CEP64_RS24585	COG4978	Transcriptional regulator
CEP64_RS24600	COG1131	(ABC) transporter
CEP64_RS24605	COG2188	Transcriptional regulator
CEP64_RS24610	COG2819	hydrolase of the alpha beta superfamily
CEP64_RS24620	COG3173	Aminoglycoside phosphotransferase
CEP64_RS24635	COG0463	Glycosyl transferase, family 2
CEP64_RS24635	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
CEP64_RS24645	COG0438	transferase activity, transferring glycosyl groups
CEP64_RS24650	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CEP64_RS24660	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CEP64_RS24665	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CEP64_RS24675	COG1486	melibiose metabolic process
CEP64_RS24695	COG1028	Short-chain dehydrogenase reductase Sdr
CEP64_RS24700	COG4175	Glycine betaine
CEP64_RS24700	COG0517	IMP dehydrogenase activity
CEP64_RS24720	COG1388	LysM domain
CEP64_RS24725	COG2910	NAD(P)H-binding
CEP64_RS24730	COG1959	2 iron, 2 sulfur cluster binding
CEP64_RS24740	COG0438	transferase activity, transferring glycosyl groups
CEP64_RS24765	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
CEP64_RS24770	COG1902	pentaerythritol trinitrate reductase activity
CEP64_RS24775	COG3037	sugar-specific permease SgaT UlaA
CEP64_RS24785	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CEP64_RS24795	COG2723	6-phospho-beta-galactosidase activity
CEP64_RS24800	COG2723	6-phospho-beta-galactosidase activity
CEP64_RS24805	COG2190	(PTS) system
CEP64_RS24805	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CEP64_RS24805	COG1263	PTS System
CEP64_RS24810	COG3711	transcriptional antiterminator
CEP64_RS24815	COG3239	Fatty acid desaturase
CEP64_RS24825	COG1363	Peptidase, m42
CEP64_RS24835	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
CEP64_RS24840	COG2357	RelA SpoT domain protein
CEP64_RS24845	COG1486	melibiose metabolic process
CEP64_RS24850	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CEP64_RS24850	COG1263	PTS System
CEP64_RS24855	COG1737	Transcriptional regulator
CEP64_RS24860	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CEP64_RS24865	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CEP64_RS24870	COG1279	arginine transmembrane transporter activity
CEP64_RS24875	COG0191	fructose-bisphosphate aldolase activity
CEP64_RS24880	COG0673	inositol 2-dehydrogenase activity
CEP64_RS24885	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CEP64_RS24890	COG1082	Xylose isomerase domain protein TIM barrel
CEP64_RS24895	COG0673	inositol 2-dehydrogenase activity
CEP64_RS24900	COG3962	Belongs to the TPP enzyme family
CEP64_RS24905	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CEP64_RS24915	COG1012	belongs to the aldehyde dehydrogenase family
CEP64_RS24920	COG1349	DNA-binding transcription factor activity
CEP64_RS24930	COG0778	Nitroreductase
CEP64_RS24935	COG1309	transcriptional regulator
CEP64_RS24940	COG1263	PTS System
CEP64_RS24940	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CEP64_RS24945	COG2824	Alkylphosphonate utilization operon protein PhnA
CEP64_RS24960	COG1131	(ABC) transporter
CEP64_RS24970	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CEP64_RS24970	COG3711	transcriptional antiterminator
CEP64_RS24975	COG2723	6-phospho-beta-galactosidase activity
CEP64_RS24980	COG1447	Phosphotransferase system cellobiose-specific component IIA
CEP64_RS24985	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CEP64_RS24995	COG1113	amino acid transport
CEP64_RS25005	COG0402	S-adenosylhomocysteine deaminase activity
CEP64_RS25010	COG1012	belongs to the aldehyde dehydrogenase family
CEP64_RS25015	COG0531	amino acid
CEP64_RS25020	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CEP64_RS25025	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CEP64_RS25060	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CEP64_RS25065	COG1136	(ABC) transporter
CEP64_RS25070	COG0577	efflux transmembrane transporter activity
CEP64_RS25075	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CEP64_RS25080	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CEP64_RS25080	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CEP64_RS25085	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CEP64_RS25090	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CEP64_RS25100	COG3711	transcriptional antiterminator
CEP64_RS25105	COG1063	alcohol dehydrogenase
CEP64_RS25115	COG2271	Major facilitator Superfamily
CEP64_RS25120	COG1028	Short-chain dehydrogenase reductase Sdr
CEP64_RS25125	COG1312	Catalyzes the dehydration of D-mannonate
CEP64_RS25130	COG1063	alcohol dehydrogenase
CEP64_RS25135	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CEP64_RS25140	COG0800	Aldolase
CEP64_RS25145	COG1414	Transcriptional regulator
CEP64_RS25150	COG0583	DNA-binding transcription factor activity
CEP64_RS25165	COG4876	unkown
CEP64_RS25205	COG4607	ABC-type enterochelin transport system periplasmic component
CEP64_RS25210	COG3708	Transcriptional regulator
CEP64_RS25210	COG2207	Transcriptional regulator
CEP64_RS25220	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CEP64_RS25225	COG0456	acetyltransferase
CEP64_RS25230	COG0765	amino acid transport
CEP64_RS25235	COG1126	abc transporter atp-binding protein
CEP64_RS25240	COG2079	MmgE PrpD family protein
CEP64_RS25245	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CEP64_RS25250	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CEP64_RS25255	COG2190	(PTS) system
CEP64_RS25255	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CEP64_RS25255	COG1263	PTS System
CEP64_RS25260	COG4948	Mandelate Racemase Muconate Lactonizing
CEP64_RS25270	COG3711	transcriptional antiterminator
CEP64_RS25280	COG0246	Mannitol dehydrogenase
CEP64_RS25290	COG0596	Alpha beta hydrolase
CEP64_RS25315	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CEP64_RS25320	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CEP64_RS25325	COG0018	arginyl-trna synthetase
CEP64_RS25340	COG1078	dGTPase activity
CEP64_RS25355	COG1028	Short-chain dehydrogenase reductase Sdr
CEP64_RS25365	COG4844	belongs to the
CEP64_RS25370	COG0095	Lipoate-protein ligase
CEP64_RS25410	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CEP64_RS25420	COG2011	ABC-type metal ion transport system permease component
CEP64_RS25435	COG0786	glutamate:sodium symporter activity
CEP64_RS25440	COG0531	amino acid
CEP64_RS25445	COG2363	Small membrane protein
CEP64_RS25455	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CEP64_RS25470	COG0363	glucosamine-6-phosphate deaminase activity
CEP64_RS25475	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
CEP64_RS25480	COG1263	PTS System
CEP64_RS25480	COG2190	(PTS) system
CEP64_RS25480	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CEP64_RS25495	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CEP64_RS25500	COG1469	GTP cyclohydrolase I activity
CEP64_RS25510	COG0431	NADPH-dependent FMN reductase
CEP64_RS25515	COG0561	phosphatase activity
CEP64_RS25525	COG1428	Deoxynucleoside kinase
CEP64_RS25530	COG1428	Deoxynucleoside kinase
CEP64_RS25540	COG1388	LysM domain
CEP64_RS25545	COG2608	mercury ion transmembrane transporter activity
CEP64_RS25555	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CEP64_RS25560	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CEP64_RS25570	COG1473	amidohydrolase
CEP64_RS25575	COG1473	amidohydrolase
CEP64_RS25580	COG1473	amidohydrolase
CEP64_RS25585	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CEP64_RS25590	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CEP64_RS25595	COG0049	tRNA binding
CEP64_RS25600	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CEP64_RS25610	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CEP64_RS25615	COG0085	RNA polymerase activity
CEP64_RS25620	COG2813	Specifically methylates the guanine in position
CEP64_RS25625	COG0222	ribosome binding
CEP64_RS25630	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CEP64_RS25635	COG0081	regulation of translation
CEP64_RS25640	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CEP64_RS25655	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CEP64_RS25670	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CEP64_RS25675	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
CEP64_RS25680	COG0215	cysteine-tRNA ligase activity
CEP64_RS25705	COG4956	integral membrane protein (PIN domain superfamily)
CEP64_RS25710	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
CEP64_RS25715	COG0542	response to heat
CEP64_RS25720	COG3869	Catalyzes the specific phosphorylation of arginine residues in
CEP64_RS25725	COG3880	PFAM UvrB UvrC protein
CEP64_RS25730	COG4463	regulation of RNA biosynthetic process
CEP64_RS25735	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CEP64_RS25745	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
CEP64_RS25750	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CEP64_RS25755	COG1289	transmembrane transporter activity
CEP64_RS25845	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CEP64_RS25865	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
CEP64_RS25870	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CEP64_RS25885	COG1098	S1 RNA binding domain
CEP64_RS25895	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
CEP64_RS25900	COG3956	TIGRFAM MazG family protein
CEP64_RS25905	COG2244	polysaccharide biosynthetic process
CEP64_RS25910	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CEP64_RS25915	COG0193	aminoacyl-tRNA hydrolase activity
CEP64_RS25925	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CEP64_RS25930	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CEP64_RS25935	COG2088	sporulation resulting in formation of a cellular spore
CEP64_RS25940	COG0251	oxidation-reduction process
CEP64_RS25945	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CEP64_RS25950	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
CEP64_RS25955	COG4466	Protein conserved in bacteria
CEP64_RS25965	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
CEP64_RS25970	COG0084	hydrolase, TatD family'
CEP64_RS25975	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CEP64_RS25975	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CEP64_RS25980	COG2002	toxin-antitoxin pair type II binding
CEP64_RS25985	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CEP64_RS25990	COG2827	Endonuclease containing a URI domain
CEP64_RS25995	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
CEP64_RS26005	COG1774	PSP1 C-terminal conserved region
CEP64_RS26010	COG0470	DNA polymerase III
CEP64_RS26015	COG3870	Protein conserved in bacteria
CEP64_RS26025	COG1982	Orn Lys Arg decarboxylase major
CEP64_RS26050	COG4667	esterase of the alpha-beta hydrolase superfamily
CEP64_RS26060	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
CEP64_RS26065	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CEP64_RS26080	COG2188	Transcriptional regulator
CEP64_RS26085	COG0366	Alpha amylase catalytic
CEP64_RS26090	COG1263	PTS System
CEP64_RS26090	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CEP64_RS26100	COG0791	NLP P60 protein
CEP64_RS26105	COG4948	Mandelate Racemase Muconate Lactonizing
CEP64_RS26110	COG1619	proteins homologs of microcin C7 resistance protein MccF
CEP64_RS26120	COG0493	'glutamate synthase
CEP64_RS26125	COG0067	glutamate synthase
CEP64_RS26125	COG0070	glutamate synthase
CEP64_RS26125	COG0069	glutamate synthase activity
CEP64_RS26130	COG0583	DNA-binding transcription factor activity
CEP64_RS26135	COG2094	Belongs to the DNA glycosylase MPG family
CEP64_RS26150	COG0346	lactoylglutathione lyase activity
CEP64_RS26160	COG2814	Major facilitator Superfamily
CEP64_RS26170	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CEP64_RS26185	COG2076	Multidrug Resistance protein
CEP64_RS26190	COG2076	Multidrug Resistance protein
CEP64_RS26210	COG1695	Transcriptional regulator
CEP64_RS26240	COG0346	lactoylglutathione lyase activity
CEP64_RS26245	COG0400	carboxylic ester hydrolase activity
CEP64_RS26285	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CEP64_RS26285	COG0519	Catalyzes the synthesis of GMP from XMP
CEP64_RS26290	COG0516	GMP reductase activity
CEP64_RS26290	COG0517	IMP dehydrogenase activity
CEP64_RS26295	COG2233	PERMEase
CEP64_RS26300	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CEP64_RS26315	COG2070	2-Nitropropane dioxygenase
CEP64_RS26320	COG0778	Nitroreductase
CEP64_RS26325	COG0733	neurotransmitter:sodium symporter activity
CEP64_RS26335	COG0471	metal ion transport
CEP64_RS26350	COG0346	lactoylglutathione lyase activity
CEP64_RS26355	COG1072	(Pantothenic acid kinase))
CEP64_RS26365	COG0384	phenazine biosynthesis protein PhzF
CEP64_RS26415	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CEP64_RS26445	COG3646	Phage regulatory protein
CEP64_RS26445	COG3645	SOS response
CEP64_RS26460	COG0582	viral genome integration into host DNA
CEP64_RS26470	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CEP64_RS26480	COG0360	Binds together with S18 to 16S ribosomal RNA
CEP64_RS26490	COG0668	transmembrane transport
CEP64_RS26495	COG1475	DNA binding
CEP64_RS26500	COG0626	cystathionine gamma-synthase activity
CEP64_RS26505	COG0626	cystathionine gamma-synthase activity
CEP64_RS26510	COG0646	methionine synthase
CEP64_RS26510	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
CEP64_RS26515	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CEP64_RS26525	COG1966	Carbon starvation protein
CEP64_RS26530	COG1475	DNA binding
CEP64_RS26535	COG0357	Ribosomal RNA small subunit methyltransferase G
CEP64_RS26540	COG0445	tRNA wobble uridine modification
CEP64_RS26545	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
CEP64_RS26555	COG0594	ribonuclease P activity
CEP64_RS26565	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CEP64_RS26570	COG0592	DNA-directed DNA polymerase activity
CEP64_RS26580	COG4152	abc transporter atp-binding protein
CEP64_RS26585	COG1668	transmembrane transport
CEP64_RS26590	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CEP64_RS26595	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
CEP64_RS26600	COG2501	S4 domain
CEP64_RS26605	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CEP64_RS26615	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CEP64_RS26620	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CEP64_RS26630	COG2986	histidine ammonia-lyase
CEP64_RS26635	COG3314	Sporulation integral membrane protein YlbJ
CEP64_RS26645	COG1228	amidohydrolase
CEP64_RS26650	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CEP64_RS26670	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CEP64_RS26680	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
CEP64_RS26685	COG0359	binds to the 23S rRNA
CEP64_RS26690	COG0305	Participates in initiation and elongation during chromosome replication
CEP64_RS26695	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CEP64_RS26705	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CEP64_RS26725	COG5002	protein histidine kinase activity
CEP64_RS26740	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
CEP64_RS26745	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
CEP64_RS26750	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
CEP64_RS26755	COG0789	Transcriptional regulator
CEP64_RS26755	COG4978	Transcriptional regulator
CEP64_RS26775	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CEP64_RS26785	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CEP64_RS26790	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CEP64_RS26800	COG4221	oxidoreductase activity
CEP64_RS26805	COG0110	maltose O-acetyltransferase activity
CEP64_RS26810	COG0583	DNA-binding transcription factor activity
CEP64_RS26830	COG1028	Short-chain dehydrogenase reductase Sdr
CEP64_RS26835	COG0583	DNA-binding transcription factor activity
CEP64_RS26845	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CEP64_RS26865	COG1063	alcohol dehydrogenase
CEP64_RS26885	COG1595	DNA-templated transcription, initiation
CEP64_RS26910	COG0415	Belongs to the DNA photolyase family
CEP64_RS26920	COG1064	alcohol dehydrogenase
CEP64_RS26930	COG2814	Major facilitator Superfamily
CEP64_RS26945	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
CEP64_RS26950	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CEP64_RS26980	COG1609	Transcriptional regulator
CEP64_RS26990	COG0235	Class ii aldolase
CEP64_RS26995	COG2160	L-arabinose isomerase activity
CEP64_RS27010	COG0640	Transcriptional regulator
CEP64_RS27030	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CEP64_RS27035	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CEP64_RS27040	COG0454	-acetyltransferase
CEP64_RS27045	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CEP64_RS27050	COG0765	amino acid transport
CEP64_RS27055	COG0765	amino acid transport
CEP64_RS27060	COG1126	abc transporter atp-binding protein
CEP64_RS27090	COG1028	Short-chain dehydrogenase reductase Sdr
CEP64_RS27110	COG1129	ABC transporter
CEP64_RS27115	COG1132	(ABC) transporter
CEP64_RS27115	COG2375	cellular response to nickel ion
CEP64_RS27120	COG1132	(ABC) transporter
CEP64_RS27135	COG0717	Belongs to the dCTP deaminase family
CEP64_RS27150	COG2146	nitrite reductase [NAD(P)H] activity
CEP64_RS27155	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CEP64_RS27170	COG1288	antiporter activity
CEP64_RS27175	COG3711	transcriptional antiterminator
CEP64_RS27180	COG1263	PTS System
CEP64_RS27180	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CEP64_RS27185	COG2723	6-phospho-beta-galactosidase activity
CEP64_RS27225	COG0025	NhaP-type Na H and K H
CEP64_RS27230	COG2508	Transcriptional regulator
CEP64_RS27235	COG1953	Uracil, thiamine, allantoin
CEP64_RS27240	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CEP64_RS27245	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CEP64_RS27255	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CEP64_RS27260	COG3257	ureidoglycine aminohydrolase activity
CEP64_RS27265	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
CEP64_RS27270	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
CEP64_RS27275	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CEP64_RS27280	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CEP64_RS27295	COG2807	transmembrane transport
CEP64_RS27300	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
CEP64_RS27305	COG2204	response regulator
CEP64_RS27315	COG1454	alcohol dehydrogenase
CEP64_RS27320	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
CEP64_RS27330	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CEP64_RS27355	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CEP64_RS27395	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CEP64_RS27400	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CEP64_RS27410	COG1609	Transcriptional regulator
CEP64_RS27415	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CEP64_RS27420	COG2610	gluconate transmembrane transporter activity
CEP64_RS27460	COG3290	protein histidine kinase activity
CEP64_RS27465	COG4565	transcriptional regulatory protein
CEP64_RS27470	COG3493	citrate carrier protein
CEP64_RS27485	COG1473	amidohydrolase
CEP64_RS27490	COG1473	amidohydrolase
CEP64_RS27495	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
CEP64_RS27510	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CEP64_RS27515	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CEP64_RS27520	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CEP64_RS27525	COG0019	diaminopimelate decarboxylase activity
CEP64_RS27535	COG4264	IucA IucC family
CEP64_RS27540	COG4264	IucA IucC family
CEP64_RS27550	COG0477	Major facilitator Superfamily
CEP64_RS27560	COG0702	epimerase
CEP64_RS27580	COG0726	polysaccharide deacetylase
CEP64_RS27590	COG1114	Component of the transport system for branched-chain amino acids
CEP64_RS27600	COG0183	Belongs to the thiolase family
CEP64_RS27605	COG3425	synthase
CEP64_RS27610	COG0477	Major facilitator Superfamily
CEP64_RS27615	COG0584	glycerophosphoryl diester phosphodiesterase
CEP64_RS27630	COG4753	response regulator
CEP64_RS27630	COG2207	Transcriptional regulator
CEP64_RS27645	COG1846	Transcriptional regulator
CEP64_RS27660	COG0531	amino acid
CEP64_RS27670	COG1028	Short-chain dehydrogenase reductase Sdr
CEP64_RS27675	COG1597	lipid kinase activity
CEP64_RS27680	COG0589	response to stress
CEP64_RS27690	COG1525	nuclease
CEP64_RS27725	COG3764	Sortase (surface protein transpeptidase)
CEP64_RS27785	COG3942	CHAP domain
CEP64_RS27785	COG1388	LysM domain
CEP64_RS27900	COG0679	Auxin Efflux Carrier
CEP64_RS27905	COG1012	belongs to the aldehyde dehydrogenase family
CEP64_RS27910	COG1733	regulation of RNA biosynthetic process
CEP64_RS27925	COG1192	Involved in chromosome partitioning
CEP64_RS27955	COG2076	Multidrug Resistance protein
CEP64_RS27970	COG1309	transcriptional regulator
CEP64_RS27975	COG1192	Involved in chromosome partitioning
CEP64_RS28060	COG0789	Transcriptional regulator
CEP64_RS28070	COG1028	Short-chain dehydrogenase reductase Sdr
CEP64_RS28080	COG2814	Major facilitator Superfamily
CEP64_RS28105	COG0726	polysaccharide deacetylase