locus-tag	class	description
JCQ35_RS00005	COG1140	nitrate reductase beta subunit
JCQ35_RS00010	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
JCQ35_RS00015	COG2181	nitrate reductase activity
JCQ35_RS00025	COG4585	Histidine kinase
JCQ35_RS00030	COG2197	response regulator
JCQ35_RS00035	COG2223	nitrite transmembrane transporter activity
JCQ35_RS00040	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
JCQ35_RS00045	COG0521	Mo-molybdopterin cofactor biosynthetic process
JCQ35_RS00050	COG0315	cyclic pyranopterin monophosphate synthase activity
JCQ35_RS00055	COG0303	'Molybdopterin
JCQ35_RS00060	COG1763	Mo-molybdopterin cofactor biosynthetic process
JCQ35_RS00075	COG0746	molybdenum cofactor guanylyltransferase activity
JCQ35_RS00080	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
JCQ35_RS00085	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
JCQ35_RS00090	COG2814	Major facilitator Superfamily
JCQ35_RS00100	COG2348	transferase activity, transferring amino-acyl groups
JCQ35_RS00105	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
JCQ35_RS00110	COG0436	Aminotransferase
JCQ35_RS00125	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
JCQ35_RS00140	COG4975	Glucose uptake
JCQ35_RS00155	COG2252	PERMEase
JCQ35_RS00165	COG0051	transcription antitermination factor activity, RNA binding
JCQ35_RS00170	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
JCQ35_RS00175	COG0088	Forms part of the polypeptide exit tunnel
JCQ35_RS00180	COG0089	rRNA binding
JCQ35_RS00185	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
JCQ35_RS00190	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
JCQ35_RS00195	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
JCQ35_RS00200	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
JCQ35_RS00205	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
JCQ35_RS00210	COG0255	Belongs to the universal ribosomal protein uL29 family
JCQ35_RS00220	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
JCQ35_RS00225	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
JCQ35_RS00230	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
JCQ35_RS00235	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
JCQ35_RS00240	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
JCQ35_RS00245	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
JCQ35_RS00250	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
JCQ35_RS00255	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
JCQ35_RS00260	COG1841	ribosomal large subunit assembly
JCQ35_RS00270	COG0201	protein transport
JCQ35_RS00285	COG0257	Belongs to the bacterial ribosomal protein bL36 family
JCQ35_RS00290	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
JCQ35_RS00300	COG0202	RNA polymerase activity
JCQ35_RS00305	COG0203	ribosomal protein L17
JCQ35_RS00325	COG0101	tRNA pseudouridine synthase activity
JCQ35_RS00330	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
JCQ35_RS00335	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
JCQ35_RS00340	COG4122	O-methyltransferase activity
JCQ35_RS00360	COG1011	Hydrolase
JCQ35_RS00365	COG1132	(ABC) transporter
JCQ35_RS00375	COG3655	Transcriptional regulator
JCQ35_RS00380	COG0346	lactoylglutathione lyase activity
JCQ35_RS00405	COG0604	alcohol dehydrogenase
JCQ35_RS00410	COG1511	domain protein
JCQ35_RS00420	COG3842	ATPase activity
JCQ35_RS00425	COG2182	Extracellular solute-binding protein
JCQ35_RS00430	COG1175	transmembrane transport
JCQ35_RS00435	COG3833	ABC-type maltose transport systems, permease component
JCQ35_RS00440	COG1609	Transcriptional regulator
JCQ35_RS00445	COG0366	Alpha amylase catalytic
JCQ35_RS00450	COG2376	Dihydroxyacetone kinase
JCQ35_RS00455	COG1461	Dihydroxyacetone kinase
JCQ35_RS00460	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
JCQ35_RS00465	COG2186	Transcriptional regulator
JCQ35_RS00470	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
JCQ35_RS00475	COG1482	cell wall glycoprotein biosynthetic process
JCQ35_RS00485	COG3942	CHAP domain
JCQ35_RS00485	COG1388	LysM domain
JCQ35_RS00495	COG1115	amino acid carrier protein
JCQ35_RS00505	COG1757	Na H antiporter
JCQ35_RS00515	COG1609	Transcriptional regulator
JCQ35_RS00520	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JCQ35_RS00525	COG1869	D-ribose catabolic process
JCQ35_RS00530	COG1129	ABC transporter
JCQ35_RS00535	COG1172	Belongs to the binding-protein-dependent transport system permease family
JCQ35_RS00540	COG1879	ABC-type sugar transport system periplasmic component
JCQ35_RS00545	COG0783	Belongs to the Dps family
JCQ35_RS00550	COG0277	FAD linked oxidase domain protein
JCQ35_RS00555	COG0247	lactate metabolic process
JCQ35_RS00560	COG0813	purine-nucleoside phosphorylase activity
JCQ35_RS00565	COG2390	Transcriptional regulator
JCQ35_RS00570	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
JCQ35_RS00580	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
JCQ35_RS00590	COG1854	S-ribosylhomocysteine lyase activity
JCQ35_RS00595	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
JCQ35_RS00595	COG0456	acetyltransferase
JCQ35_RS00635	COG5146	pantothenate kinase activity
JCQ35_RS00640	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
JCQ35_RS00645	COG4589	Belongs to the CDS family
JCQ35_RS00675	COG3343	RNA polymerase activity
JCQ35_RS00680	COG0504	CTP synthase activity
JCQ35_RS00685	COG4821	SIS domain
JCQ35_RS00695	COG0191	fructose-bisphosphate aldolase activity
JCQ35_RS00700	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
JCQ35_RS00715	COG2801	Transposase and inactivated derivatives
JCQ35_RS00725	COG1012	belongs to the aldehyde dehydrogenase family
JCQ35_RS00730	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
JCQ35_RS00735	COG0254	rRNA binding
JCQ35_RS00740	COG1435	thymidine kinase activity
JCQ35_RS00750	COG2890	protein-(glutamine-N5) methyltransferase activity
JCQ35_RS00755	COG0009	L-threonylcarbamoyladenylate synthase
JCQ35_RS00760	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
JCQ35_RS00765	COG0698	ribose 5-phosphate isomerase
JCQ35_RS00770	COG4475	Protein of unknown function (DUF436)
JCQ35_RS00775	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
JCQ35_RS00780	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
JCQ35_RS00785	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
JCQ35_RS00795	COG0356	it plays a direct role in the translocation of protons across the membrane
JCQ35_RS00800	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
JCQ35_RS00805	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
JCQ35_RS00810	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
JCQ35_RS00815	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
JCQ35_RS00820	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
JCQ35_RS00825	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
JCQ35_RS00850	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
JCQ35_RS00860	COG0629	single-stranded DNA binding
JCQ35_RS00865	COG1388	LysM domain
JCQ35_RS00875	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
JCQ35_RS00880	COG0352	thiamine-phosphate diphosphorylase activity
JCQ35_RS00885	COG0706	membrane insertase activity
JCQ35_RS00890	COG1418	mRNA catabolic process
JCQ35_RS00895	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
JCQ35_RS00905	COG0772	Belongs to the SEDS family
JCQ35_RS00910	COG1181	Belongs to the D-alanine--D-alanine ligase family
JCQ35_RS00915	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
JCQ35_RS00925	COG0513	Belongs to the DEAD box helicase family
JCQ35_RS00965	COG2208	phosphoserine phosphatase activity
JCQ35_RS00980	COG1191	sigma factor activity
JCQ35_RS00985	COG2183	response to ionizing radiation
JCQ35_RS00990	COG3091	SprT-like family
JCQ35_RS01020	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
JCQ35_RS01030	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
JCQ35_RS01035	COG0473	3-isopropylmalate dehydrogenase activity
JCQ35_RS01040	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
JCQ35_RS01045	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
JCQ35_RS01055	COG0028	Belongs to the TPP enzyme family
JCQ35_RS01060	COG0129	dihydroxy-acid dehydratase activity
JCQ35_RS01065	COG0802	atpase or kinase
JCQ35_RS01070	COG1214	PFAM Peptidase M22, glycoprotease
JCQ35_RS01075	COG0456	acetyltransferase
JCQ35_RS01095	COG0488	(ABC) transporter
JCQ35_RS01100	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
JCQ35_RS01105	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
JCQ35_RS01110	COG0805	protein transport
JCQ35_RS01115	COG2391	methyltransferase activity
JCQ35_RS01120	COG0425	Belongs to the sulfur carrier protein TusA family
JCQ35_RS01125	COG1609	Transcriptional regulator
JCQ35_RS01130	COG1621	beta-fructofuranosidase activity
JCQ35_RS01170	COG0459	protein refolding
JCQ35_RS01180	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
JCQ35_RS01200	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JCQ35_RS01205	COG1131	(ABC) transporter
JCQ35_RS01220	COG1131	(ABC) transporter
JCQ35_RS01235	COG1473	amidohydrolase
JCQ35_RS01240	COG1802	Transcriptional regulator
JCQ35_RS01245	COG1070	Carbohydrate kinase
JCQ35_RS01250	COG2610	gluconate transmembrane transporter activity
JCQ35_RS01255	COG2223	nitrite transmembrane transporter activity
JCQ35_RS01285	COG0385	Bile acid
JCQ35_RS01325	COG4512	PFAM Accessory gene regulator B
JCQ35_RS01330	COG2706	6-phosphogluconolactonase activity
JCQ35_RS01340	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
JCQ35_RS01345	COG0390	transport system, permease component
JCQ35_RS01350	COG1012	belongs to the aldehyde dehydrogenase family
JCQ35_RS01355	COG0673	inositol 2-dehydrogenase activity
JCQ35_RS01370	COG1227	inorganic diphosphatase activity
JCQ35_RS01375	COG1335	isochorismatase
JCQ35_RS01390	COG0077	Prephenate dehydratase
JCQ35_RS01405	COG0107	imidazoleglycerol-phosphate synthase activity
JCQ35_RS01410	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
JCQ35_RS01415	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
JCQ35_RS01420	COG0131	Imidazoleglycerol-phosphate dehydratase
JCQ35_RS01425	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
JCQ35_RS01430	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
JCQ35_RS01435	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
JCQ35_RS01440	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
JCQ35_RS01445	COG0477	Major facilitator Superfamily
JCQ35_RS01450	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
JCQ35_RS01455	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
JCQ35_RS01460	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
JCQ35_RS01470	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
JCQ35_RS01475	COG4496	protein, YerC YecD
JCQ35_RS01480	COG1876	peptidase activity
JCQ35_RS01485	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
JCQ35_RS01490	COG0210	DNA helicase
JCQ35_RS01495	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
JCQ35_RS01500	COG4851	CamS sex pheromone cAM373 precursor
JCQ35_RS01505	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
JCQ35_RS01510	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
JCQ35_RS01520	COG0154	amidase activity
JCQ35_RS01525	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
JCQ35_RS01530	COG0433	COG0433 Predicted ATPase
JCQ35_RS01535	COG1597	lipid kinase activity
JCQ35_RS01565	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
JCQ35_RS01580	COG1528	Iron-storage protein
JCQ35_RS01595	COG4129	membrane
JCQ35_RS01600	COG0024	Methionine aminopeptidase
JCQ35_RS01620	COG2197	response regulator
JCQ35_RS01625	COG0288	reversible hydration of carbon dioxide
JCQ35_RS01630	COG1295	ribonuclease BN
JCQ35_RS01645	COG4840	Belongs to the UPF0435 family
JCQ35_RS01650	COG2309	aminopeptidase activity
JCQ35_RS01660	COG1607	acyl-coa hydrolase
JCQ35_RS01665	COG0535	radical SAM domain protein
JCQ35_RS01675	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
JCQ35_RS01680	COG0693	protein deglycase activity
JCQ35_RS01690	COG0028	Belongs to the TPP enzyme family
JCQ35_RS01695	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
JCQ35_RS01700	COG2137	regulation of response to DNA damage stimulus
JCQ35_RS01710	COG1134	teichoic acid transport
JCQ35_RS01720	COG1988	membrane-bound metal-dependent
JCQ35_RS01725	COG1194	a g-specific adenine glycosylase
JCQ35_RS01730	COG3557	Belongs to the UPF0374 family
JCQ35_RS01740	COG0069	glutamate synthase activity
JCQ35_RS01745	COG4129	membrane
JCQ35_RS01750	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
JCQ35_RS01755	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
JCQ35_RS01765	COG0735	belongs to the Fur family
JCQ35_RS01920	COG1609	Transcriptional regulator
JCQ35_RS01950	COG1904	glucuronate isomerase
JCQ35_RS01965	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
JCQ35_RS01970	COG0765	amino acid transport
JCQ35_RS01975	COG1126	abc transporter atp-binding protein
JCQ35_RS01980	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
JCQ35_RS01985	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
JCQ35_RS01990	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
JCQ35_RS01995	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
JCQ35_RS02000	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
JCQ35_RS02010	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
JCQ35_RS02015	COG0363	glucosamine-6-phosphate deaminase activity
JCQ35_RS02025	COG0114	fumarate hydratase activity
JCQ35_RS02030	COG0248	Ppx GppA phosphatase
JCQ35_RS02035	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
JCQ35_RS02040	COG0564	pseudouridine synthase activity
JCQ35_RS02045	COG3153	acetyltransferase
JCQ35_RS02045	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
JCQ35_RS02050	COG2203	Gaf domain
JCQ35_RS02050	COG4585	Histidine kinase
JCQ35_RS02055	COG2197	response regulator
JCQ35_RS02060	COG1301	dicarboxylic acid transport
JCQ35_RS02070	COG4399	Belongs to the UPF0754 family
JCQ35_RS02075	COG3679	Belongs to the UPF0342 family
JCQ35_RS02080	COG0420	3'-5' exonuclease activity
JCQ35_RS02090	COG3481	metal-dependent phosphohydrolase, HD sub domain
JCQ35_RS02095	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
JCQ35_RS02105	COG1846	Transcriptional regulator
JCQ35_RS02115	COG0537	adenosine 5'-monophosphoramidase activity
JCQ35_RS02120	COG1131	(ABC) transporter
JCQ35_RS02130	COG2329	Antibiotic biosynthesis monooxygenase
JCQ35_RS02135	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
JCQ35_RS02140	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
JCQ35_RS02145	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
JCQ35_RS02200	COG0456	acetyltransferase
JCQ35_RS02210	COG2814	Major facilitator Superfamily
JCQ35_RS02235	COG0494	nUDIX hydrolase
JCQ35_RS02240	COG1506	peptidase
JCQ35_RS02245	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
JCQ35_RS02250	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
JCQ35_RS02260	COG1012	belongs to the aldehyde dehydrogenase family
JCQ35_RS02265	COG0656	L-ascorbic acid biosynthetic process
JCQ35_RS02270	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
JCQ35_RS02290	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
JCQ35_RS02295	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
JCQ35_RS02315	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
JCQ35_RS02340	COG1595	DNA-templated transcription, initiation
JCQ35_RS02385	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
JCQ35_RS02385	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
JCQ35_RS02390	COG0307	riboflavin synthase, alpha
JCQ35_RS02395	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
JCQ35_RS02395	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
JCQ35_RS02405	COG0506	proline dehydrogenase activity
JCQ35_RS02420	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
JCQ35_RS02425	COG2267	carboxylic ester hydrolase activity
JCQ35_RS02445	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
JCQ35_RS02450	COG1242	4 iron, 4 sulfur cluster binding
JCQ35_RS02455	COG2814	Major facilitator Superfamily
JCQ35_RS02460	COG0495	leucyl-tRNA aminoacylation
JCQ35_RS02465	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
JCQ35_RS02470	COG2081	HI0933 family
JCQ35_RS02475	COG2244	polysaccharide biosynthetic process
JCQ35_RS02480	COG1187	pseudouridine synthase activity
JCQ35_RS02500	COG0510	thiamine kinase activity
JCQ35_RS02505	COG0220	tRNA (guanine-N7-)-methyltransferase activity
JCQ35_RS02510	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JCQ35_RS02515	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
JCQ35_RS02525	COG1363	Peptidase, m42
JCQ35_RS02530	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JCQ35_RS02535	COG0765	amino acid transport
JCQ35_RS02540	COG1126	abc transporter atp-binding protein
JCQ35_RS02550	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JCQ35_RS02555	COG4848	Belongs to the UPF0354 family
JCQ35_RS02560	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JCQ35_RS02565	COG1674	ftsk spoiiie
JCQ35_RS02570	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
JCQ35_RS02575	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
JCQ35_RS02580	COG4980	gas vesicle protein
JCQ35_RS02585	COG1605	Chorismate mutase
JCQ35_RS02585	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
JCQ35_RS02590	COG1609	Transcriptional regulator
JCQ35_RS02595	COG0123	including yeast histone deacetylase and acetoin utilization protein
JCQ35_RS02600	COG0517	IMP dehydrogenase activity
JCQ35_RS02605	COG0454	-acetyltransferase
JCQ35_RS02610	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
JCQ35_RS02615	COG2759	Belongs to the formate--tetrahydrofolate ligase family
JCQ35_RS02620	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
JCQ35_RS02625	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
JCQ35_RS02630	COG1704	LemA family
JCQ35_RS02640	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JCQ35_RS02645	COG0204	Acyl-transferase
JCQ35_RS02660	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
JCQ35_RS02670	COG1764	response to oxidative stress
JCQ35_RS02685	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
JCQ35_RS02690	COG1956	GAF domain-containing protein
JCQ35_RS02695	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
JCQ35_RS02700	COG1104	cysteine desulfurase activity
JCQ35_RS02705	COG0301	tRNA thio-modification
JCQ35_RS02715	COG2801	Transposase and inactivated derivatives
JCQ35_RS02730	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
JCQ35_RS02735	COG0616	signal peptide processing
JCQ35_RS02740	COG1714	RDD family
JCQ35_RS02745	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
JCQ35_RS02750	COG0827	DNA restriction-modification system
JCQ35_RS02755	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
JCQ35_RS02770	COG0589	response to stress
JCQ35_RS02775	COG0686	Belongs to the AlaDH PNT family
JCQ35_RS02780	COG3142	Participates in the control of copper homeostasis
JCQ35_RS02785	COG0006	proline dipeptidase activity
JCQ35_RS02790	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
JCQ35_RS02795	COG4109	DRTGG domain
JCQ35_RS02805	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
JCQ35_RS02815	COG0281	malic enzyme
JCQ35_RS02820	COG1725	Transcriptional regulator
JCQ35_RS02825	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
JCQ35_RS02830	COG0825	malonyl-CoA metabolic process
JCQ35_RS02835	COG0205	6-phosphofructokinase activity
JCQ35_RS02840	COG0469	pyruvate kinase activity
JCQ35_RS02845	COG1113	amino acid transport
JCQ35_RS02850	COG0372	Belongs to the citrate synthase family
JCQ35_RS02855	COG0538	isocitrate dehydrogenase activity
JCQ35_RS02865	COG0745	RESPONSE REGULATOR receiver
JCQ35_RS02870	COG5002	protein histidine kinase activity
JCQ35_RS02875	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
JCQ35_RS02875	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
JCQ35_RS02880	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
JCQ35_RS02885	COG0237	dephospho-CoA kinase activity
JCQ35_RS02890	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
JCQ35_RS02900	COG3611	Membrane attachment protein
JCQ35_RS02905	COG1484	DNA-dependent DNA replication
JCQ35_RS02915	COG0833	amino acid
JCQ35_RS02920	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
JCQ35_RS02925	COG0291	Belongs to the bacterial ribosomal protein bL35 family
JCQ35_RS02930	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
JCQ35_RS02935	COG4112	unkown
JCQ35_RS02945	COG0544	peptidyl-prolyl cis-trans isomerase activity
JCQ35_RS02950	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
JCQ35_RS02955	COG0218	Necessary for normal cell division and for the maintenance of normal septation
JCQ35_RS02960	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
JCQ35_RS02965	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
JCQ35_RS02970	COG0181	hydroxymethylbilane synthase activity
JCQ35_RS02980	COG0113	porphobilinogen synthase activity
JCQ35_RS02985	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
JCQ35_RS02995	COG0525	valine-tRNA ligase activity
JCQ35_RS03000	COG0285	dihydrofolate synthase activity
JCQ35_RS03005	COG1288	antiporter activity
JCQ35_RS03010	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
JCQ35_RS03035	COG2249	NAD(P)H dehydrogenase (quinone) activity
JCQ35_RS03040	COG0477	Major facilitator Superfamily
JCQ35_RS03050	COG2003	Belongs to the UPF0758 family
JCQ35_RS03095	COG0488	(ABC) transporter
JCQ35_RS03110	COG1132	(ABC) transporter
JCQ35_RS03115	COG1132	(ABC) transporter
JCQ35_RS03125	COG1792	Involved in formation and maintenance of cell shape
JCQ35_RS03135	COG0261	This protein binds to 23S rRNA in the presence of protein L20
JCQ35_RS03140	COG2868	ribosomal protein
JCQ35_RS03145	COG0211	Belongs to the bacterial ribosomal protein bL27 family
JCQ35_RS03155	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
JCQ35_RS03160	COG4492	Belongs to the UPF0735 family
JCQ35_RS03165	COG0632	four-way junction helicase activity
JCQ35_RS03170	COG2255	four-way junction helicase activity
JCQ35_RS03180	COG0343	queuine tRNA-ribosyltransferase activity
JCQ35_RS03185	COG1862	Preprotein translocase
JCQ35_RS03190	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
JCQ35_RS03190	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
JCQ35_RS03195	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
JCQ35_RS03195	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
JCQ35_RS03205	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
JCQ35_RS03215	COG0860	N-Acetylmuramoyl-L-alanine amidase
JCQ35_RS03220	COG0124	histidyl-tRNA synthetase
JCQ35_RS03225	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
JCQ35_RS03235	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
JCQ35_RS03240	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
JCQ35_RS03245	COG1959	2 iron, 2 sulfur cluster binding
JCQ35_RS03255	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JCQ35_RS03260	COG0488	(ABC) transporter
JCQ35_RS03265	COG1104	cysteine desulfurase activity
JCQ35_RS03270	COG0482	sulfurtransferase activity
JCQ35_RS03280	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
JCQ35_RS03285	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
JCQ35_RS03290	COG4472	Bacterial protein of unknown function (DUF965)
JCQ35_RS03295	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
JCQ35_RS03305	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
JCQ35_RS03310	COG4122	O-methyltransferase activity
JCQ35_RS03315	COG0826	peptidase U32
JCQ35_RS03320	COG0826	peptidase U32
JCQ35_RS03325	COG0572	uridine kinase
JCQ35_RS03330	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
JCQ35_RS03335	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
JCQ35_RS03340	COG1984	allophanate hydrolase subunit 2
JCQ35_RS03350	COG0439	Biotin carboxylase
JCQ35_RS03355	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
JCQ35_RS03360	COG1914	H( )-stimulated, divalent metal cation uptake system
JCQ35_RS03365	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
JCQ35_RS03370	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
JCQ35_RS03375	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
JCQ35_RS03385	COG1534	Rna-binding protein
JCQ35_RS03390	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
JCQ35_RS03395	COG1713	HD superfamily hydrolase involved in NAD metabolism
JCQ35_RS03400	COG0799	negative regulation of ribosome biogenesis
JCQ35_RS03405	COG2226	methyltransferase
JCQ35_RS03410	COG1596	polysaccharide export
JCQ35_RS03410	COG1555	photosystem II stabilization
JCQ35_RS03415	COG2131	deaminase
JCQ35_RS03420	COG2333	competence protein COMEC
JCQ35_RS03420	COG0658	competence protein
JCQ35_RS03430	COG1466	dna polymerase III delta subunit
JCQ35_RS03435	COG0268	Binds directly to 16S ribosomal RNA
JCQ35_RS03440	COG0481	GTPase activity
JCQ35_RS03445	COG0635	Involved in the biosynthesis of porphyrin-containing compound
JCQ35_RS03455	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
JCQ35_RS03460	COG0443	Heat shock 70 kDa protein
JCQ35_RS03470	COG2264	protein methyltransferase activity
JCQ35_RS03475	COG1385	rRNA (uridine-N3-)-methyltransferase activity
JCQ35_RS03480	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
JCQ35_RS03485	COG0828	Belongs to the bacterial ribosomal protein bS21 family
JCQ35_RS03490	COG1030	water channel activity
JCQ35_RS03495	COG4864	UPF0365 protein
JCQ35_RS03510	COG1702	phosphate starvation-inducible protein PhoH
JCQ35_RS03515	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
JCQ35_RS03520	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
JCQ35_RS03525	COG0295	cytidine deaminase activity
JCQ35_RS03530	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
JCQ35_RS03535	COG1381	Involved in DNA repair and RecF pathway recombination
JCQ35_RS03540	COG0423	glycine-tRNA ligase activity
JCQ35_RS03545	COG0517	IMP dehydrogenase activity
JCQ35_RS03550	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
JCQ35_RS03555	COG0358	DNA primase activity
JCQ35_RS03560	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
JCQ35_RS03565	COG2010	Cytochrome c
JCQ35_RS03570	COG2384	SAM-dependent methyltransferase
JCQ35_RS03580	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
JCQ35_RS03585	COG0513	Belongs to the DEAD box helicase family
JCQ35_RS03590	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
JCQ35_RS03595	COG1121	(ABC) transporter
JCQ35_RS03600	COG1108	ABC-type Mn2 Zn2 transport systems permease components
JCQ35_RS03605	COG0735	belongs to the Fur family
JCQ35_RS03610	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
JCQ35_RS03615	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
JCQ35_RS03625	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
JCQ35_RS03630	COG0768	penicillin binding
JCQ35_RS03635	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
JCQ35_RS03640	COG0573	inorganic phosphate transmembrane transporter activity
JCQ35_RS03645	COG0581	inorganic phosphate transmembrane transporter activity
JCQ35_RS03650	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
JCQ35_RS03655	COG0704	Plays a role in the regulation of phosphate uptake
JCQ35_RS03660	COG0267	Belongs to the bacterial ribosomal protein bL33 family
JCQ35_RS03665	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
JCQ35_RS03670	COG0457	Tetratricopeptide repeat
JCQ35_RS03670	COG0705	Rhomboid family
JCQ35_RS03675	COG4483	Protein conserved in bacteria
JCQ35_RS03680	COG1940	carbohydrate kinase activity
JCQ35_RS03685	COG0011	TIGRFAM Protein of
JCQ35_RS03695	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JCQ35_RS03705	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
JCQ35_RS03710	COG1459	type II secretion system
JCQ35_RS03740	COG0404	The glycine cleavage system catalyzes the degradation of glycine
JCQ35_RS03745	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
JCQ35_RS03750	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
JCQ35_RS03755	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
JCQ35_RS03760	COG0095	Lipoate-protein ligase
JCQ35_RS03775	COG0006	proline dipeptidase activity
JCQ35_RS03780	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
JCQ35_RS03785	COG0511	ligase activity, forming carbon-carbon bonds
JCQ35_RS03790	COG0439	Biotin carboxylase
JCQ35_RS03795	COG1302	Protein conserved in bacteria
JCQ35_RS03805	COG1570	exodeoxyribonuclease VII activity
JCQ35_RS03820	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
JCQ35_RS03825	COG1438	arginine binding
JCQ35_RS03830	COG0497	DNA recombination
JCQ35_RS03845	COG0280	phosphate acetyltransferase
JCQ35_RS03860	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
JCQ35_RS03865	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
JCQ35_RS03870	COG0022	dehydrogenase e1 component
JCQ35_RS03875	COG0508	dehydrogenase complex catalyzes the overall conversion of
JCQ35_RS03885	COG4129	membrane
JCQ35_RS03895	COG2195	Cleaves the N-terminal amino acid of tripeptides
JCQ35_RS03905	COG2207	Transcriptional regulator
JCQ35_RS03905	COG1917	Cupin 2, conserved barrel domain protein
JCQ35_RS03910	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
JCQ35_RS03915	COG1234	tRNA 3'-trailer cleavage
JCQ35_RS03920	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
JCQ35_RS03930	COG0667	Aldo Keto reductase
JCQ35_RS03940	COG0735	belongs to the Fur family
JCQ35_RS03945	COG4974	Belongs to the 'phage' integrase family
JCQ35_RS03950	COG1547	Domain of unknown function (DUF309)
JCQ35_RS03955	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
JCQ35_RS03960	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
JCQ35_RS03965	COG1187	pseudouridine synthase activity
JCQ35_RS03970	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JCQ35_RS03975	COG1333	cytochrome c biogenesis protein
JCQ35_RS03980	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
JCQ35_RS03985	COG0745	RESPONSE REGULATOR receiver
JCQ35_RS03990	COG5002	protein histidine kinase activity
JCQ35_RS04000	COG1141	Ferredoxin
JCQ35_RS04005	COG4955	Helix-turn-helix domain
JCQ35_RS04010	COG0514	ATP-dependent DNA helicase (RecQ)
JCQ35_RS04025	COG0492	ferredoxin-NADP+ reductase activity
JCQ35_RS04030	COG0252	asparaginase activity
JCQ35_RS04035	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
JCQ35_RS04040	COG0539	negative regulation of cytoplasmic translation
JCQ35_RS04045	COG1160	GTP binding
JCQ35_RS04050	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
JCQ35_RS04075	COG2226	methyltransferase
JCQ35_RS04080	COG0142	geranyltranstransferase activity
JCQ35_RS04085	COG0105	UTP biosynthetic process
JCQ35_RS04090	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
JCQ35_RS04095	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
JCQ35_RS04100	COG0457	Tetratricopeptide repeat
JCQ35_RS04120	COG0723	plastoquinol--plastocyanin reductase activity
JCQ35_RS04125	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
JCQ35_RS04140	COG2738	Putative neutral zinc metallopeptidase
JCQ35_RS04145	COG1694	Mazg nucleotide pyrophosphohydrolase
JCQ35_RS04150	COG0438	transferase activity, transferring glycosyl groups
JCQ35_RS04155	COG0617	tRNA 3'-terminal CCA addition
JCQ35_RS04165	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
JCQ35_RS04165	COG1199	ATP-dependent helicase activity
JCQ35_RS04175	COG3935	DnaD domain protein
JCQ35_RS04180	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
JCQ35_RS04195	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
JCQ35_RS04195	COG4499	WXG100 protein secretion system (Wss), protein YukC
JCQ35_RS04200	COG3331	DNA recombination
JCQ35_RS04210	COG4474	Belongs to the UPF0398 family
JCQ35_RS04215	COG3599	regulation of cell shape
JCQ35_RS04225	COG0116	Belongs to the methyltransferase superfamily
JCQ35_RS04240	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
JCQ35_RS04250	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
JCQ35_RS04255	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
JCQ35_RS04260	COG0328	RNA-DNA hybrid ribonuclease activity
JCQ35_RS04280	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
JCQ35_RS04290	COG1413	lyase activity
JCQ35_RS04305	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
JCQ35_RS04315	COG0204	Acyl-transferase
JCQ35_RS04335	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
JCQ35_RS04340	COG2190	(PTS) system
JCQ35_RS04345	COG4479	Belongs to the UPF0346 family
JCQ35_RS04365	COG0671	phosphoesterase, PA-phosphatase related
JCQ35_RS04375	COG5002	protein histidine kinase activity
JCQ35_RS04380	COG0567	Dehydrogenase, E1 component
JCQ35_RS04400	COG2267	carboxylic ester hydrolase activity
JCQ35_RS04415	COG0714	Associated with various cellular activities
JCQ35_RS04420	COG4548	von Willebrand factor, type A
JCQ35_RS04425	COG1114	Component of the transport system for branched-chain amino acids
JCQ35_RS04430	COG5505	Protein of unknown function (DUF819)
JCQ35_RS04435	COG2801	Transposase and inactivated derivatives
JCQ35_RS04455	COG3853	Toxic anion resistance protein (TelA)
JCQ35_RS04465	COG1254	Belongs to the acylphosphatase family
JCQ35_RS04500	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
JCQ35_RS04505	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
JCQ35_RS04510	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
JCQ35_RS04515	COG0527	aspartate kinase activity
JCQ35_RS04520	COG0488	(ABC) transporter
JCQ35_RS04525	COG2996	Protein conserved in bacteria
JCQ35_RS04530	COG3711	transcriptional antiterminator
JCQ35_RS04535	COG1447	Phosphotransferase system cellobiose-specific component IIA
JCQ35_RS04540	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
JCQ35_RS04540	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
JCQ35_RS04545	COG2723	6-phospho-beta-galactosidase activity
JCQ35_RS04550	COG3328	transposase activity
JCQ35_RS04555	COG3684	Belongs to the aldolase LacD family
JCQ35_RS04560	COG1105	Belongs to the carbohydrate kinase PfkB family
JCQ35_RS04565	COG0698	ribose 5-phosphate isomerase
JCQ35_RS04575	COG1349	DNA-binding transcription factor activity
JCQ35_RS04580	COG1164	Oligoendopeptidase f
JCQ35_RS04595	COG0789	Transcriptional regulator
JCQ35_RS04620	COG0159	tryptophan synthase activity
JCQ35_RS04630	COG0135	phosphoribosylanthranilate isomerase activity
JCQ35_RS04640	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
JCQ35_RS04650	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
JCQ35_RS04655	COG1363	Peptidase, m42
JCQ35_RS04660	COG0287	Prephenate dehydrogenase
JCQ35_RS04675	COG2801	Transposase and inactivated derivatives
JCQ35_RS04690	COG1476	TRANSCRIPTIONal
JCQ35_RS04695	COG1757	Na H antiporter
JCQ35_RS04700	COG1929	Belongs to the glycerate kinase type-1 family
JCQ35_RS04705	COG0471	metal ion transport
JCQ35_RS04725	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
JCQ35_RS04760	COG0586	Pfam SNARE associated Golgi protein
JCQ35_RS04780	COG0628	permease
JCQ35_RS04785	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JCQ35_RS04785	COG2190	(PTS) system
JCQ35_RS04785	COG1263	PTS System
JCQ35_RS04790	COG3711	transcriptional antiterminator
JCQ35_RS04800	COG1115	amino acid carrier protein
JCQ35_RS04805	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
JCQ35_RS04815	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
JCQ35_RS04820	COG4841	protein insertion into membrane
JCQ35_RS04825	COG0824	Thioesterase
JCQ35_RS04835	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
JCQ35_RS04840	COG1970	mechanosensitive ion channel activity
JCQ35_RS04845	COG1999	signal sequence binding
JCQ35_RS04865	COG4846	Membrane protein involved in cytochrome C biogenesis
JCQ35_RS04870	COG0785	Cytochrome C biogenesis protein
JCQ35_RS04875	COG3763	UPF0154 protein
JCQ35_RS04885	COG4224	UPF0291 protein
JCQ35_RS04895	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
JCQ35_RS04910	COG0516	GMP reductase activity
JCQ35_RS04915	COG0803	Belongs to the bacterial solute-binding protein 9 family
JCQ35_RS04920	COG0267	Belongs to the bacterial ribosomal protein bL33 family
JCQ35_RS04925	COG0833	amino acid
JCQ35_RS04940	COG0640	Transcriptional regulator
JCQ35_RS04960	COG0083	homoserine kinase activity
JCQ35_RS04965	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
JCQ35_RS04970	COG0460	homoserine dehydrogenase
JCQ35_RS04975	COG0527	aspartate kinase activity
JCQ35_RS04990	COG2084	Dehydrogenase
JCQ35_RS05005	COG1597	lipid kinase activity
JCQ35_RS05045	COG0110	maltose O-acetyltransferase activity
JCQ35_RS05075	COG0789	Transcriptional regulator
JCQ35_RS05080	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
JCQ35_RS05085	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
JCQ35_RS05090	COG0386	Belongs to the glutathione peroxidase family
JCQ35_RS05095	COG1923	regulation of RNA biosynthetic process
JCQ35_RS05100	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
JCQ35_RS05105	COG2267	carboxylic ester hydrolase activity
JCQ35_RS05110	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
JCQ35_RS05115	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
JCQ35_RS05120	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
JCQ35_RS05125	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
JCQ35_RS05130	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
JCQ35_RS05135	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
JCQ35_RS05145	COG4550	Control of competence regulator ComK, YlbF/YmcA
JCQ35_RS05150	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
JCQ35_RS05160	COG1132	(ABC) transporter
JCQ35_RS05165	COG1132	(ABC) transporter
JCQ35_RS05175	COG1013	pyruvate-flavodoxin oxidoreductase activity
JCQ35_RS05180	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
JCQ35_RS05180	COG0674	pyruvate-flavodoxin oxidoreductase activity
JCQ35_RS05185	COG1692	metallophosphoesterase
JCQ35_RS05195	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
JCQ35_RS05195	COG0463	Glycosyl transferase, family 2
JCQ35_RS05230	COG0561	phosphatase activity
JCQ35_RS05240	COG0697	spore germination
JCQ35_RS05265	COG1418	mRNA catabolic process
JCQ35_RS05270	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
JCQ35_RS05275	COG1546	Belongs to the CinA family
JCQ35_RS05275	COG1058	Belongs to the CinA family
JCQ35_RS05295	COG0300	oxidoreductase activity
JCQ35_RS05300	COG0612	Peptidase, M16
JCQ35_RS05310	COG2188	Transcriptional regulator
JCQ35_RS05320	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
JCQ35_RS05325	COG0612	Peptidase, M16
JCQ35_RS05330	COG1185	polyribonucleotide nucleotidyltransferase activity
JCQ35_RS05340	COG0196	riboflavin kinase activity
JCQ35_RS05345	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
JCQ35_RS05350	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
JCQ35_RS05355	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
JCQ35_RS05360	COG1263	PTS System
JCQ35_RS05360	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JCQ35_RS05380	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
JCQ35_RS05385	COG2169	Transcriptional regulator
JCQ35_RS05400	COG3850	Histidine kinase
JCQ35_RS05400	COG5002	protein histidine kinase activity
JCQ35_RS05405	COG0745	RESPONSE REGULATOR receiver
JCQ35_RS05415	COG1929	Belongs to the glycerate kinase type-1 family
JCQ35_RS05420	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
JCQ35_RS05425	COG1358	cellular component organization or biogenesis
JCQ35_RS05430	COG2740	Nucleic-acid-binding protein implicated in transcription termination
JCQ35_RS05435	COG0195	Participates in both transcription termination and antitermination
JCQ35_RS05440	COG0779	Required for maturation of 30S ribosomal subunits
JCQ35_RS05450	COG0442	prolyl-tRNA aminoacylation
JCQ35_RS05460	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
JCQ35_RS05465	COG4589	Belongs to the CDS family
JCQ35_RS05475	COG0233	cytoplasmic translational termination
JCQ35_RS05480	COG0528	UMP kinase activity
JCQ35_RS05485	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
JCQ35_RS05490	COG0052	Belongs to the universal ribosomal protein uS2 family
JCQ35_RS05500	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
JCQ35_RS05505	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
JCQ35_RS05510	COG4974	Belongs to the 'phage' integrase family
JCQ35_RS05515	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
JCQ35_RS05520	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
JCQ35_RS05525	COG0758	DNA mediated transformation
JCQ35_RS05535	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
JCQ35_RS05540	COG0045	succinate-CoA ligase (ADP-forming) activity
JCQ35_RS05545	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
JCQ35_RS05550	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
JCQ35_RS05555	COG0463	Glycosyl transferase, family 2
JCQ35_RS05560	COG4485	Bacterial membrane protein, YfhO
JCQ35_RS05565	COG0335	large ribosomal subunit rRNA binding
JCQ35_RS05570	COG0336	Belongs to the RNA methyltransferase TrmD family
JCQ35_RS05580	COG1837	Belongs to the UPF0109 family
JCQ35_RS05585	COG0228	four-way junction DNA binding
JCQ35_RS05590	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
JCQ35_RS05595	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
JCQ35_RS05600	COG0552	protein localization to endoplasmic reticulum
JCQ35_RS05605	COG1196	nuclear chromosome segregation
JCQ35_RS05620	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
JCQ35_RS05635	COG0416	fatty acid biosynthetic process
JCQ35_RS05640	COG1349	DNA-binding transcription factor activity
JCQ35_RS05645	COG3328	transposase activity
JCQ35_RS05655	COG3764	Sortase (surface protein transpeptidase)
JCQ35_RS05660	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
JCQ35_RS05665	COG1760	l-serine dehydratase
JCQ35_RS05670	COG1760	l-serine dehydratase
JCQ35_RS05680	COG1302	Protein conserved in bacteria
JCQ35_RS05685	COG0227	Belongs to the bacterial ribosomal protein bL28 family
JCQ35_RS05690	COG1564	THIamine pyrophosphokinase
JCQ35_RS05695	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
JCQ35_RS05700	COG1162	GTPase activity
JCQ35_RS05705	COG3850	Histidine kinase
JCQ35_RS05705	COG5002	protein histidine kinase activity
JCQ35_RS05710	COG0745	RESPONSE REGULATOR receiver
JCQ35_RS05715	COG2124	cytochrome p450
JCQ35_RS05735	COG0820	rRNA (adenine-C2-)-methyltransferase activity
JCQ35_RS05740	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
JCQ35_RS05740	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
JCQ35_RS05745	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
JCQ35_RS05750	COG0242	peptide deformylase activity
JCQ35_RS05790	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
JCQ35_RS05790	COG0463	Glycosyl transferase, family 2
JCQ35_RS05795	COG0438	transferase activity, transferring glycosyl groups
JCQ35_RS05835	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
JCQ35_RS05840	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
JCQ35_RS05845	COG1758	RNA polymerase activity
JCQ35_RS05875	COG5632	N-Acetylmuramoyl-L-alanine amidase
JCQ35_RS05875	COG1388	LysM domain
JCQ35_RS05910	COG5434	Belongs to the glycosyl hydrolase 28 family
JCQ35_RS06145	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
JCQ35_RS06155	COG0471	metal ion transport
JCQ35_RS06170	COG0284	orotidine-5'-phosphate decarboxylase activity
JCQ35_RS06175	COG0167	dihydroorotate dehydrogenase activity
JCQ35_RS06180	COG0543	2 iron, 2 sulfur cluster binding
JCQ35_RS06185	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
JCQ35_RS06190	COG0505	Belongs to the CarA family
JCQ35_RS06200	COG0540	Belongs to the ATCase OTCase family
JCQ35_RS06210	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
JCQ35_RS06215	COG0564	pseudouridine synthase activity
JCQ35_RS06220	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
JCQ35_RS06230	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
JCQ35_RS06235	COG3599	regulation of cell shape
JCQ35_RS06245	COG0762	integral membrane protein
JCQ35_RS06250	COG1799	cell septum assembly
JCQ35_RS06255	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
JCQ35_RS06260	COG1496	oxidoreductase activity
JCQ35_RS06265	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
JCQ35_RS06270	COG0849	cell division
JCQ35_RS06275	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
JCQ35_RS06280	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
JCQ35_RS06285	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
JCQ35_RS06290	COG0768	penicillin binding
JCQ35_RS06295	COG4839	cell division protein FtsL
JCQ35_RS06300	COG0275	rRNA processing
JCQ35_RS06305	COG2001	Belongs to the MraZ family
JCQ35_RS06310	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
JCQ35_RS06315	COG0454	-acetyltransferase
JCQ35_RS06365	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
JCQ35_RS06375	COG1846	Transcriptional regulator
JCQ35_RS06380	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
JCQ35_RS06385	COG1053	succinate dehydrogenase
JCQ35_RS06390	COG2009	succinate dehydrogenase
JCQ35_RS06395	COG0322	excinuclease ABC activity
JCQ35_RS06400	COG3118	belongs to the thioredoxin family
JCQ35_RS06405	COG1024	Enoyl-CoA hydratase
JCQ35_RS06415	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
JCQ35_RS06415	COG1796	DNA polymerase
JCQ35_RS06425	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
JCQ35_RS06430	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
JCQ35_RS06435	COG0072	phenylalanine-tRNA ligase activity
JCQ35_RS06435	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JCQ35_RS06440	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
JCQ35_RS06445	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
JCQ35_RS06465	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
JCQ35_RS06470	COG0742	ribosomal rna small subunit methyltransferase
JCQ35_RS06480	COG4471	UPF0298 protein
JCQ35_RS06485	COG0584	glycerophosphoryl diester phosphodiesterase
JCQ35_RS06490	COG3679	Belongs to the UPF0342 family
JCQ35_RS06495	COG2340	Cysteine-rich secretory protein family
JCQ35_RS06505	COG0628	permease
JCQ35_RS06510	COG2322	membrane
JCQ35_RS06515	COG3336	cytochrome c oxidase
JCQ35_RS06540	COG0109	protoheme IX farnesyltransferase activity
JCQ35_RS06545	COG1612	heme a metabolic process
JCQ35_RS06555	COG0772	Belongs to the SEDS family
JCQ35_RS06560	COG4838	Belongs to the UPF0358 family
JCQ35_RS06570	COG4896	Protein conserved in bacteria
JCQ35_RS06580	COG1217	gtp-binding protein TYPA
JCQ35_RS06590	COG0483	inositol monophosphate 1-phosphatase activity
JCQ35_RS06610	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
JCQ35_RS06615	COG1177	transmembrane transport
JCQ35_RS06620	COG1176	ABC-type spermidine putrescine transport system, permease component I
JCQ35_RS06625	COG3842	ATPase activity
JCQ35_RS06635	COG4476	Belongs to the UPF0223 family
JCQ35_RS06655	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
JCQ35_RS06665	COG0242	peptide deformylase activity
JCQ35_RS06675	COG0561	phosphatase activity
JCQ35_RS06680	COG5503	Protein of unknown function (DUF1447)
JCQ35_RS06690	COG0569	domain protein
JCQ35_RS06700	COG1271	oxidase subunit
JCQ35_RS06710	COG1408	metallophosphoesterase
JCQ35_RS06730	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JCQ35_RS06740	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
JCQ35_RS06755	COG1122	ATPase activity
JCQ35_RS06765	COG0151	Belongs to the GarS family
JCQ35_RS06770	COG0138	bifunctional purine biosynthesis protein purh
JCQ35_RS06780	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
JCQ35_RS06795	COG0047	phosphoribosylformylglycinamidine synthase activity
JCQ35_RS06800	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
JCQ35_RS06805	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
JCQ35_RS06815	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
JCQ35_RS06825	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
JCQ35_RS06825	COG1017	nitric oxide dioxygenase activity
JCQ35_RS06830	COG1959	2 iron, 2 sulfur cluster binding
JCQ35_RS06840	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
JCQ35_RS06845	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
JCQ35_RS06850	COG1845	cytochrome c oxidase, subunit III
JCQ35_RS06855	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
JCQ35_RS06870	COG1134	teichoic acid transport
JCQ35_RS06880	COG1682	transport, permease protein
JCQ35_RS06900	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
JCQ35_RS06915	COG0463	Glycosyl transferase, family 2
JCQ35_RS06915	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
JCQ35_RS06920	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
JCQ35_RS06920	COG0463	Glycosyl transferase, family 2
JCQ35_RS06925	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
JCQ35_RS06940	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
JCQ35_RS06945	COG1682	transport, permease protein
JCQ35_RS06950	COG1134	teichoic acid transport
JCQ35_RS06975	COG0183	Belongs to the thiolase family
JCQ35_RS06980	COG0318	PFAM AMP-dependent synthetase and ligase
JCQ35_RS06985	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
JCQ35_RS06990	COG1316	TRANSCRIPTIONal
JCQ35_RS07000	COG2153	protein acetylation
JCQ35_RS07010	COG3594	Acyltransferase
JCQ35_RS07020	COG0436	Aminotransferase
JCQ35_RS07025	COG4187	Peptidase family M20/M25/M40
JCQ35_RS07030	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
JCQ35_RS07035	COG0596	Alpha beta hydrolase
JCQ35_RS07045	COG1169	isochorismate synthase
JCQ35_RS07050	COG1575	Belongs to the MenA family. Type 1 subfamily
JCQ35_RS07070	COG1647	Serine aminopeptidase, S33
JCQ35_RS07165	COG4873	Protein conserved in bacteria
JCQ35_RS07175	COG0737	Belongs to the 5'-nucleotidase family
JCQ35_RS07180	COG3852	Histidine kinase
JCQ35_RS07185	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
JCQ35_RS07190	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JCQ35_RS07190	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JCQ35_RS07195	COG0861	Integral membrane protein TerC family
JCQ35_RS07200	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
JCQ35_RS07210	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
JCQ35_RS07230	COG2814	Major facilitator Superfamily
JCQ35_RS07235	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
JCQ35_RS07240	COG2382	esterase
JCQ35_RS07245	COG1115	amino acid carrier protein
JCQ35_RS07250	COG0628	permease
JCQ35_RS07260	COG0475	glutathione-regulated potassium exporter activity
JCQ35_RS07260	COG0569	domain protein
JCQ35_RS07265	COG2239	Acts as a magnesium transporter
JCQ35_RS07270	COG0564	pseudouridine synthase activity
JCQ35_RS07280	COG2357	RelA SpoT domain protein
JCQ35_RS07290	COG4116	CYTH
JCQ35_RS07295	COG2346	COG2346, Truncated hemoglobins
JCQ35_RS07300	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
JCQ35_RS07305	COG1164	Oligoendopeptidase f
JCQ35_RS07315	COG4862	establishment of competence for transformation
JCQ35_RS07320	COG1393	Belongs to the ArsC family
JCQ35_RS07330	COG4166	transmembrane transport
JCQ35_RS07335	COG4166	transmembrane transport
JCQ35_RS07340	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
JCQ35_RS07350	COG4166	transmembrane transport
JCQ35_RS07355	COG4166	transmembrane transport
JCQ35_RS07360	COG4608	Belongs to the ABC transporter superfamily
JCQ35_RS07365	COG0444	Belongs to the ABC transporter superfamily
JCQ35_RS07370	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JCQ35_RS07375	COG0601	transmembrane transport
JCQ35_RS07400	COG0542	response to heat
JCQ35_RS07405	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
JCQ35_RS07410	COG2151	metal-sulfur cluster biosynthetic enzyme
JCQ35_RS07415	COG0561	phosphatase activity
JCQ35_RS07420	COG1307	EDD domain protein, DegV family
JCQ35_RS07430	COG1874	Beta-galactosidase
JCQ35_RS07430	COG0366	Alpha amylase catalytic
JCQ35_RS07440	COG0179	Fumarylacetoacetate (FAA) hydrolase
JCQ35_RS07445	COG2311	Membrane
JCQ35_RS07450	COG1074	ATP-dependent DNA helicase activity
JCQ35_RS07455	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
JCQ35_RS07470	COG0398	Pfam SNARE associated Golgi protein
JCQ35_RS07485	COG0137	argininosuccinate synthase activity
JCQ35_RS07490	COG0165	Argininosuccinate lyase
JCQ35_RS07500	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
JCQ35_RS07505	COG1012	belongs to the aldehyde dehydrogenase family
JCQ35_RS07510	COG1098	S1 RNA binding domain
JCQ35_RS07520	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
JCQ35_RS07530	COG2111	Na H antiporter
JCQ35_RS07530	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
JCQ35_RS07535	COG2111	Na H antiporter
JCQ35_RS07550	COG1863	multisubunit Na H antiporter MnhE subunit
JCQ35_RS07555	COG2212	antiporter activity
JCQ35_RS07560	COG1320	monovalent cation:proton antiporter activity
JCQ35_RS07565	COG2050	protein possibly involved in aromatic compounds catabolism
JCQ35_RS07570	COG2056	Na+-H+ antiporter family
JCQ35_RS07575	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
JCQ35_RS07585	COG1252	NADH dehydrogenase
JCQ35_RS07590	COG0316	Belongs to the HesB IscA family
JCQ35_RS07595	COG4844	belongs to the
JCQ35_RS07600	COG1252	NADH dehydrogenase
JCQ35_RS07605	COG3328	transposase activity
JCQ35_RS07610	COG4837	Protein of unknown function (DUF1462)
JCQ35_RS07615	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
JCQ35_RS07620	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
JCQ35_RS07625	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
JCQ35_RS07630	COG1696	Membrane protein involved in D-alanine export
JCQ35_RS07645	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
JCQ35_RS07650	COG0647	UMP catabolic process
JCQ35_RS07655	COG2445	Protein of unknown function DUF86
JCQ35_RS07665	COG4470	Protein conserved in bacteria
JCQ35_RS07670	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
JCQ35_RS07675	COG0737	Belongs to the 5'-nucleotidase family
JCQ35_RS07680	COG0730	response to heat
JCQ35_RS07685	COG1801	Protein of unknown function DUF72
JCQ35_RS07695	COG0860	N-Acetylmuramoyl-L-alanine amidase
JCQ35_RS07695	COG1388	LysM domain
JCQ35_RS07705	COG1395	domain, Protein
JCQ35_RS07720	COG0800	Aldolase
JCQ35_RS07725	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JCQ35_RS07730	COG1028	Short-chain dehydrogenase reductase Sdr
JCQ35_RS07735	COG1940	carbohydrate kinase activity
JCQ35_RS07740	COG2814	Major facilitator Superfamily
JCQ35_RS07755	COG0719	Fe-S assembly protein
JCQ35_RS07760	COG0822	iron-sulfur transferase activity
JCQ35_RS07770	COG0719	Fe-S assembly protein
JCQ35_RS07775	COG0396	ATPase activity
JCQ35_RS07790	COG1464	Belongs to the NlpA lipoprotein family
JCQ35_RS07795	COG2011	ABC-type metal ion transport system permease component
JCQ35_RS07800	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
JCQ35_RS07810	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
JCQ35_RS07815	COG0509	glycine decarboxylation via glycine cleavage system
JCQ35_RS07820	COG1393	Belongs to the ArsC family
JCQ35_RS07825	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JCQ35_RS07830	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
JCQ35_RS07830	COG0778	Nitroreductase
JCQ35_RS07835	COG0710	3-dehydroquinate dehydratase activity
JCQ35_RS07855	COG2801	Transposase and inactivated derivatives
JCQ35_RS07870	COG0697	spore germination
JCQ35_RS07875	COG1764	response to oxidative stress
JCQ35_RS07900	COG1694	Mazg nucleotide pyrophosphohydrolase
JCQ35_RS07915	COG4166	transmembrane transport
JCQ35_RS07920	COG4166	transmembrane transport
JCQ35_RS07930	COG1011	Hydrolase
JCQ35_RS07940	COG0456	acetyltransferase
JCQ35_RS07940	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
JCQ35_RS07950	COG0523	cobalamin synthesis protein
JCQ35_RS07955	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
JCQ35_RS08010	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
JCQ35_RS08025	COG0477	Major facilitator Superfamily
JCQ35_RS08045	COG0406	alpha-ribazole phosphatase activity
JCQ35_RS08050	COG1525	nuclease
JCQ35_RS08065	COG1280	lysine exporter protein (LysE YggA)
JCQ35_RS08070	COG0477	Major facilitator Superfamily
JCQ35_RS08100	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JCQ35_RS08105	COG0730	response to heat
JCQ35_RS08115	COG2249	NAD(P)H dehydrogenase (quinone) activity
JCQ35_RS08125	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
JCQ35_RS08130	COG0557	exoribonuclease II activity
JCQ35_RS08135	COG1647	Serine aminopeptidase, S33
JCQ35_RS08140	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
JCQ35_RS08145	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
JCQ35_RS08150	COG0148	phosphopyruvate hydratase activity
JCQ35_RS08160	COG0149	triose-phosphate isomerase activity
JCQ35_RS08165	COG0126	phosphoglycerate kinase activity
JCQ35_RS08185	COG0740	serine-type endopeptidase activity
JCQ35_RS08190	COG1481	regulation of sporulation
JCQ35_RS08200	COG0391	Required for morphogenesis under gluconeogenic growth conditions
JCQ35_RS08205	COG1660	Displays ATPase and GTPase activities
JCQ35_RS08220	COG0110	maltose O-acetyltransferase activity
JCQ35_RS08225	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
JCQ35_RS08230	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
JCQ35_RS08245	COG0556	nucleotide-excision repair
JCQ35_RS08260	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JCQ35_RS08265	COG3942	CHAP domain
JCQ35_RS08270	COG2010	Cytochrome c
JCQ35_RS08280	COG0653	protein targeting
JCQ35_RS08285	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
JCQ35_RS08290	COG1040	competence protein
JCQ35_RS08295	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
JCQ35_RS08300	COG1307	EDD domain protein, DegV family
JCQ35_RS08310	COG1739	Uncharacterized protein family UPF0029
JCQ35_RS08315	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
JCQ35_RS08320	COG2199	diguanylate cyclase activity
JCQ35_RS08325	COG2966	Psort location CytoplasmicMembrane, score
JCQ35_RS08335	COG2195	Cleaves the N-terminal amino acid of tripeptides
JCQ35_RS08340	COG1929	Belongs to the glycerate kinase type-1 family
JCQ35_RS08380	COG2801	Transposase and inactivated derivatives
JCQ35_RS08385	COG4607	ABC-type enterochelin transport system periplasmic component
JCQ35_RS08390	COG4604	ABC transporter, ATP-binding protein
JCQ35_RS08395	COG4605	iron ion homeostasis
JCQ35_RS08400	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JCQ35_RS08410	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
JCQ35_RS08415	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
JCQ35_RS08420	COG1780	Probably involved in ribonucleotide reductase function
JCQ35_RS08430	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
JCQ35_RS08435	COG3104	oligopeptide transport
JCQ35_RS08440	COG3104	oligopeptide transport
JCQ35_RS08445	COG4502	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
JCQ35_RS08455	COG1174	glycine betaine transport
JCQ35_RS08460	COG1125	glycine betaine transport
JCQ35_RS08460	COG0517	IMP dehydrogenase activity
JCQ35_RS08465	COG0514	ATP-dependent DNA helicase (RecQ)
JCQ35_RS08470	COG0488	(ABC) transporter
JCQ35_RS08480	COG1368	sulfuric ester hydrolase activity
JCQ35_RS08485	COG1984	allophanate hydrolase subunit 2
JCQ35_RS08500	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
JCQ35_RS08505	COG0512	Glutamine amidotransferase of anthranilate synthase
JCQ35_RS08515	COG0720	synthase
JCQ35_RS08520	COG0602	queuosine metabolic process
JCQ35_RS08530	COG1695	Transcriptional regulator
JCQ35_RS08550	COG0656	L-ascorbic acid biosynthetic process
JCQ35_RS08555	COG1187	pseudouridine synthase activity
JCQ35_RS08560	COG2814	Major facilitator Superfamily
JCQ35_RS08565	COG1253	flavin adenine dinucleotide binding
JCQ35_RS08570	COG2267	carboxylic ester hydrolase activity
JCQ35_RS08575	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JCQ35_RS08575	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JCQ35_RS08575	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JCQ35_RS08580	COG1105	Belongs to the carbohydrate kinase PfkB family
JCQ35_RS08585	COG1349	DNA-binding transcription factor activity
JCQ35_RS08590	COG1473	amidohydrolase
JCQ35_RS08595	COG4989	oxidoreductase activity
JCQ35_RS08600	COG0523	cobalamin synthesis protein
JCQ35_RS08610	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
JCQ35_RS08615	COG4988	ABC transporter
JCQ35_RS08630	COG1671	Belongs to the UPF0178 family
JCQ35_RS08645	COG1683	Conserved Protein
JCQ35_RS08660	COG1012	belongs to the aldehyde dehydrogenase family
JCQ35_RS08680	COG0025	NhaP-type Na H and K H
JCQ35_RS08705	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JCQ35_RS08710	COG0765	amino acid transport
JCQ35_RS08715	COG0765	amino acid transport
JCQ35_RS08720	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JCQ35_RS08725	COG1126	abc transporter atp-binding protein
JCQ35_RS08740	COG1136	(ABC) transporter
JCQ35_RS08745	COG0577	efflux transmembrane transporter activity
JCQ35_RS08755	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
JCQ35_RS08760	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
JCQ35_RS08775	COG1263	PTS System
JCQ35_RS08775	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JCQ35_RS08785	COG0010	Belongs to the arginase family
JCQ35_RS08790	COG1914	H( )-stimulated, divalent metal cation uptake system
JCQ35_RS08830	COG2818	Glycosylase
JCQ35_RS08840	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
JCQ35_RS08855	COG0667	Aldo Keto reductase
JCQ35_RS08860	COG0492	ferredoxin-NADP+ reductase activity
JCQ35_RS08865	COG2207	Transcriptional regulator
JCQ35_RS08870	COG2271	Major facilitator Superfamily
JCQ35_RS08875	COG3226	Transcriptional regulator
JCQ35_RS08885	COG1253	flavin adenine dinucleotide binding
JCQ35_RS08895	COG2197	response regulator
JCQ35_RS08900	COG4585	Histidine kinase
JCQ35_RS08905	COG0842	Transport permease protein
JCQ35_RS08910	COG1131	(ABC) transporter
JCQ35_RS08915	COG0672	)-iron permease
JCQ35_RS08920	COG2837	iron assimilation
JCQ35_RS08925	COG2822	iron ion transport
JCQ35_RS08945	COG3634	alkyl hydroperoxide reductase activity
JCQ35_RS08955	COG1132	(ABC) transporter
JCQ35_RS08960	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
JCQ35_RS08960	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
JCQ35_RS08970	COG1447	Phosphotransferase system cellobiose-specific component IIA
JCQ35_RS08975	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JCQ35_RS08975	COG3711	transcriptional antiterminator
JCQ35_RS08980	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
JCQ35_RS08985	COG2723	6-phospho-beta-galactosidase activity
JCQ35_RS08995	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
JCQ35_RS09005	COG3443	Belongs to the bacterial solute-binding protein 9 family
JCQ35_RS09005	COG0803	Belongs to the bacterial solute-binding protein 9 family
JCQ35_RS09015	COG1136	(ABC) transporter
JCQ35_RS09030	COG4607	ABC-type enterochelin transport system periplasmic component
JCQ35_RS09040	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
JCQ35_RS09045	COG2162	N-hydroxyarylamine O-acetyltransferase activity
JCQ35_RS09055	COG0477	Major facilitator Superfamily
JCQ35_RS09060	COG0477	Major facilitator Superfamily
JCQ35_RS09070	COG3732	PTS system glucitol sorbitol-specific
JCQ35_RS09075	COG3730	PTS system glucitol sorbitol-specific
JCQ35_RS09085	COG3711	transcriptional antiterminator
JCQ35_RS09085	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JCQ35_RS09095	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
JCQ35_RS09100	COG0740	serine-type endopeptidase activity
JCQ35_RS09105	COG1309	transcriptional regulator
JCQ35_RS09115	COG0400	carboxylic ester hydrolase activity
JCQ35_RS09120	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
JCQ35_RS09125	COG0346	lactoylglutathione lyase activity
JCQ35_RS09130	COG1846	Transcriptional regulator
JCQ35_RS09135	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
JCQ35_RS09140	COG0626	cystathionine gamma-synthase activity
JCQ35_RS09150	COG4978	Transcriptional regulator
JCQ35_RS09150	COG0789	Transcriptional regulator
JCQ35_RS09165	COG1131	(ABC) transporter
JCQ35_RS09170	COG2188	Transcriptional regulator
JCQ35_RS09175	COG2819	hydrolase of the alpha beta superfamily
JCQ35_RS09180	COG0693	protein deglycase activity
JCQ35_RS09185	COG3173	Aminoglycoside phosphotransferase
JCQ35_RS09195	COG0584	glycerophosphoryl diester phosphodiesterase
JCQ35_RS09200	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
JCQ35_RS09200	COG0463	Glycosyl transferase, family 2
JCQ35_RS09225	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
JCQ35_RS09230	COG1210	Utp--glucose-1-phosphate uridylyltransferase
JCQ35_RS09240	COG1486	melibiose metabolic process
JCQ35_RS09245	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
JCQ35_RS09265	COG1388	LysM domain
JCQ35_RS09270	COG2910	NAD(P)H-binding
JCQ35_RS09275	COG1959	2 iron, 2 sulfur cluster binding
JCQ35_RS09285	COG0438	transferase activity, transferring glycosyl groups
JCQ35_RS09290	COG3328	transposase activity
JCQ35_RS09300	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
JCQ35_RS09305	COG1902	pentaerythritol trinitrate reductase activity
JCQ35_RS09310	COG3037	sugar-specific permease SgaT UlaA
JCQ35_RS09320	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JCQ35_RS09325	COG2801	Transposase and inactivated derivatives
JCQ35_RS09340	COG2723	6-phospho-beta-galactosidase activity
JCQ35_RS09345	COG2723	6-phospho-beta-galactosidase activity
JCQ35_RS09350	COG1263	PTS System
JCQ35_RS09350	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JCQ35_RS09350	COG2190	(PTS) system
JCQ35_RS09355	COG3711	transcriptional antiterminator
JCQ35_RS09365	COG3239	Fatty acid desaturase
JCQ35_RS09375	COG1363	Peptidase, m42
JCQ35_RS09385	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
JCQ35_RS09390	COG2357	RelA SpoT domain protein
JCQ35_RS09395	COG1486	melibiose metabolic process
JCQ35_RS09400	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JCQ35_RS09400	COG1263	PTS System
JCQ35_RS09405	COG1737	Transcriptional regulator
JCQ35_RS09410	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
JCQ35_RS09415	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JCQ35_RS09420	COG1279	arginine transmembrane transporter activity
JCQ35_RS09430	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JCQ35_RS09430	COG1263	PTS System
JCQ35_RS09435	COG2824	Alkylphosphonate utilization operon protein PhnA
JCQ35_RS09450	COG1131	(ABC) transporter
JCQ35_RS09465	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JCQ35_RS09465	COG3711	transcriptional antiterminator
JCQ35_RS09470	COG2723	6-phospho-beta-galactosidase activity
JCQ35_RS09475	COG1447	Phosphotransferase system cellobiose-specific component IIA
JCQ35_RS09480	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
JCQ35_RS09490	COG1113	amino acid transport
JCQ35_RS09505	COG0402	S-adenosylhomocysteine deaminase activity
JCQ35_RS09510	COG1012	belongs to the aldehyde dehydrogenase family
JCQ35_RS09515	COG0531	amino acid
JCQ35_RS09520	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
JCQ35_RS09525	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JCQ35_RS09530	COG2017	converts alpha-aldose to the beta-anomer
JCQ35_RS09555	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
JCQ35_RS09560	COG1028	Short-chain dehydrogenase reductase Sdr
JCQ35_RS09565	COG1312	Catalyzes the dehydration of D-mannonate
JCQ35_RS09570	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JCQ35_RS09575	COG0800	Aldolase
JCQ35_RS09580	COG1414	Transcriptional regulator
JCQ35_RS09585	COG0583	DNA-binding transcription factor activity
JCQ35_RS09600	COG4876	unkown
JCQ35_RS09635	COG4607	ABC-type enterochelin transport system periplasmic component
JCQ35_RS09640	COG3708	Transcriptional regulator
JCQ35_RS09640	COG2207	Transcriptional regulator
JCQ35_RS09650	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JCQ35_RS09655	COG0456	acetyltransferase
JCQ35_RS09660	COG0765	amino acid transport
JCQ35_RS09665	COG1126	abc transporter atp-binding protein
JCQ35_RS09670	COG2079	MmgE PrpD family protein
JCQ35_RS09675	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JCQ35_RS09685	COG3711	transcriptional antiterminator
JCQ35_RS09695	COG0246	Mannitol dehydrogenase
JCQ35_RS09715	COG0596	Alpha beta hydrolase
JCQ35_RS09730	COG0596	Alpha beta hydrolase
JCQ35_RS09740	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JCQ35_RS09745	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
JCQ35_RS09750	COG0018	arginyl-trna synthetase
JCQ35_RS09765	COG1078	dGTPase activity
JCQ35_RS09800	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
JCQ35_RS09805	COG4844	belongs to the
JCQ35_RS09810	COG0095	Lipoate-protein ligase
JCQ35_RS09850	COG2011	ABC-type metal ion transport system permease component
JCQ35_RS09865	COG0786	glutamate:sodium symporter activity
JCQ35_RS09870	COG0531	amino acid
JCQ35_RS09875	COG2363	Small membrane protein
JCQ35_RS09885	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
JCQ35_RS09900	COG0363	glucosamine-6-phosphate deaminase activity
JCQ35_RS09905	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
JCQ35_RS09910	COG1263	PTS System
JCQ35_RS09910	COG2190	(PTS) system
JCQ35_RS09910	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JCQ35_RS09915	COG1737	Transcriptional regulator
JCQ35_RS09925	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
JCQ35_RS09930	COG1469	GTP cyclohydrolase I activity
JCQ35_RS09940	COG0431	NADPH-dependent FMN reductase
JCQ35_RS09945	COG0561	phosphatase activity
JCQ35_RS09955	COG1428	Deoxynucleoside kinase
JCQ35_RS09960	COG1428	Deoxynucleoside kinase
JCQ35_RS09970	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
JCQ35_RS09975	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
JCQ35_RS09985	COG1473	amidohydrolase
JCQ35_RS09990	COG1473	amidohydrolase
JCQ35_RS09995	COG1473	amidohydrolase
JCQ35_RS10000	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
JCQ35_RS10005	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
JCQ35_RS10010	COG0049	tRNA binding
JCQ35_RS10015	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
JCQ35_RS10025	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
JCQ35_RS10030	COG0085	RNA polymerase activity
JCQ35_RS10035	COG2813	Specifically methylates the guanine in position
JCQ35_RS10040	COG0222	ribosome binding
JCQ35_RS10045	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
JCQ35_RS10050	COG0081	regulation of translation
JCQ35_RS10055	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
JCQ35_RS10070	COG0267	Belongs to the bacterial ribosomal protein bL33 family
JCQ35_RS10085	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
JCQ35_RS10090	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
JCQ35_RS10095	COG0215	cysteine-tRNA ligase activity
JCQ35_RS10120	COG4956	integral membrane protein (PIN domain superfamily)
JCQ35_RS10125	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
JCQ35_RS10130	COG0542	response to heat
JCQ35_RS10135	COG3869	Catalyzes the specific phosphorylation of arginine residues in
JCQ35_RS10140	COG3880	PFAM UvrB UvrC protein
JCQ35_RS10145	COG4463	regulation of RNA biosynthetic process
JCQ35_RS10150	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
JCQ35_RS10155	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
JCQ35_RS10160	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
JCQ35_RS10165	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JCQ35_RS10170	COG1289	transmembrane transporter activity
JCQ35_RS10260	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
JCQ35_RS10280	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
JCQ35_RS10285	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
JCQ35_RS10300	COG1098	S1 RNA binding domain
JCQ35_RS10310	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
JCQ35_RS10315	COG3956	TIGRFAM MazG family protein
JCQ35_RS10320	COG2244	polysaccharide biosynthetic process
JCQ35_RS10325	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
JCQ35_RS10330	COG0193	aminoacyl-tRNA hydrolase activity
JCQ35_RS10340	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
JCQ35_RS10345	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
JCQ35_RS10350	COG2088	sporulation resulting in formation of a cellular spore
JCQ35_RS10355	COG0251	oxidation-reduction process
JCQ35_RS10360	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
JCQ35_RS10365	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
JCQ35_RS10370	COG4466	Protein conserved in bacteria
JCQ35_RS10380	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
JCQ35_RS10385	COG0084	hydrolase, TatD family'
JCQ35_RS10390	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JCQ35_RS10390	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JCQ35_RS10395	COG2002	toxin-antitoxin pair type II binding
JCQ35_RS10400	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
JCQ35_RS10405	COG2827	Endonuclease containing a URI domain
JCQ35_RS10410	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
JCQ35_RS10420	COG1774	PSP1 C-terminal conserved region
JCQ35_RS10425	COG0470	DNA polymerase III
JCQ35_RS10430	COG3870	Protein conserved in bacteria
JCQ35_RS10440	COG1982	Orn Lys Arg decarboxylase major
JCQ35_RS10465	COG4667	esterase of the alpha-beta hydrolase superfamily
JCQ35_RS10475	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
JCQ35_RS10480	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
JCQ35_RS10495	COG2188	Transcriptional regulator
JCQ35_RS10500	COG0366	Alpha amylase catalytic
JCQ35_RS10505	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JCQ35_RS10505	COG1263	PTS System
JCQ35_RS10515	COG0791	NLP P60 protein
JCQ35_RS10520	COG4948	Mandelate Racemase Muconate Lactonizing
JCQ35_RS10525	COG1619	proteins homologs of microcin C7 resistance protein MccF
JCQ35_RS10535	COG0493	'glutamate synthase
JCQ35_RS10540	COG0067	glutamate synthase
JCQ35_RS10540	COG0069	glutamate synthase activity
JCQ35_RS10540	COG0070	glutamate synthase
JCQ35_RS10545	COG0583	DNA-binding transcription factor activity
JCQ35_RS10550	COG2094	Belongs to the DNA glycosylase MPG family
JCQ35_RS10565	COG0346	lactoylglutathione lyase activity
JCQ35_RS10575	COG2814	Major facilitator Superfamily
JCQ35_RS10585	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
JCQ35_RS10600	COG2076	Multidrug Resistance protein
JCQ35_RS10605	COG2076	Multidrug Resistance protein
JCQ35_RS10625	COG1695	Transcriptional regulator
JCQ35_RS10655	COG0346	lactoylglutathione lyase activity
JCQ35_RS10660	COG0400	carboxylic ester hydrolase activity
JCQ35_RS10690	COG0518	GMP synthase (glutamine-hydrolyzing) activity
JCQ35_RS10690	COG0519	Catalyzes the synthesis of GMP from XMP
JCQ35_RS10695	COG0516	GMP reductase activity
JCQ35_RS10695	COG0517	IMP dehydrogenase activity
JCQ35_RS10700	COG2233	PERMEase
JCQ35_RS10705	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
JCQ35_RS10720	COG2070	2-Nitropropane dioxygenase
JCQ35_RS10725	COG0778	Nitroreductase
JCQ35_RS10730	COG0733	neurotransmitter:sodium symporter activity
JCQ35_RS10735	COG0471	metal ion transport
JCQ35_RS10750	COG0346	lactoylglutathione lyase activity
JCQ35_RS10755	COG1072	(Pantothenic acid kinase))
JCQ35_RS10760	COG0384	phenazine biosynthesis protein PhzF
JCQ35_RS10780	COG3152	Membrane
JCQ35_RS10790	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
JCQ35_RS10800	COG0360	Binds together with S18 to 16S ribosomal RNA
JCQ35_RS10810	COG0012	GTP binding
JCQ35_RS10815	COG4481	Protein conserved in bacteria
JCQ35_RS10820	COG0668	transmembrane transport
JCQ35_RS10825	COG1475	DNA binding
JCQ35_RS10830	COG0626	cystathionine gamma-synthase activity
JCQ35_RS10835	COG0626	cystathionine gamma-synthase activity
JCQ35_RS10840	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
JCQ35_RS10840	COG0646	methionine synthase
JCQ35_RS10845	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
JCQ35_RS10855	COG1966	Carbon starvation protein
JCQ35_RS10860	COG1475	DNA binding
JCQ35_RS10865	COG0357	Ribosomal RNA small subunit methyltransferase G
JCQ35_RS10870	COG0445	tRNA wobble uridine modification
JCQ35_RS10875	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
JCQ35_RS10885	COG0594	ribonuclease P activity
JCQ35_RS10895	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
JCQ35_RS10900	COG0592	DNA-directed DNA polymerase activity
JCQ35_RS10910	COG4152	abc transporter atp-binding protein
JCQ35_RS10915	COG1668	transmembrane transport
JCQ35_RS10920	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
JCQ35_RS10925	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
JCQ35_RS10930	COG2501	S4 domain
JCQ35_RS10935	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
JCQ35_RS10945	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
JCQ35_RS10955	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
JCQ35_RS10965	COG2986	histidine ammonia-lyase
JCQ35_RS10975	COG1228	amidohydrolase
JCQ35_RS10980	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
JCQ35_RS11000	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
JCQ35_RS11010	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
JCQ35_RS11015	COG0359	binds to the 23S rRNA
JCQ35_RS11020	COG0305	Participates in initiation and elongation during chromosome replication
JCQ35_RS11025	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
JCQ35_RS11035	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
JCQ35_RS11055	COG5002	protein histidine kinase activity
JCQ35_RS11070	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
JCQ35_RS11075	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
JCQ35_RS11090	COG0584	glycerophosphoryl diester phosphodiesterase
JCQ35_RS11095	COG2030	dehydratase
JCQ35_RS11120	COG1940	carbohydrate kinase activity
JCQ35_RS11120	COG1846	Transcriptional regulator
JCQ35_RS11130	COG2210	Belongs to the sulfur carrier protein TusA family
JCQ35_RS11135	COG1937	Protein conserved in bacteria
JCQ35_RS11140	COG0730	response to heat
JCQ35_RS11175	COG2003	Belongs to the UPF0758 family
JCQ35_RS11260	COG2226	methyltransferase
JCQ35_RS11295	COG1695	Transcriptional regulator
JCQ35_RS11315	COG2217	Heavy metal translocating P-type atpase
JCQ35_RS11320	COG1388	LysM domain
JCQ35_RS11330	COG0702	epimerase
JCQ35_RS11335	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
JCQ35_RS11370	COG0415	Belongs to the DNA photolyase family
JCQ35_RS11385	COG0730	response to heat
JCQ35_RS11390	COG1937	Protein conserved in bacteria
JCQ35_RS11395	COG2210	Belongs to the sulfur carrier protein TusA family
JCQ35_RS11400	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JCQ35_RS11410	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
JCQ35_RS11415	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
JCQ35_RS11425	COG0446	pyridine nucleotide-disulphide oxidoreductase
JCQ35_RS11445	COG0640	Transcriptional regulator
JCQ35_RS11460	COG1486	melibiose metabolic process
JCQ35_RS11465	COG2211	Major facilitator Superfamily
JCQ35_RS11485	COG1063	alcohol dehydrogenase
JCQ35_RS11505	COG1595	DNA-templated transcription, initiation
JCQ35_RS11530	COG0415	Belongs to the DNA photolyase family
JCQ35_RS11540	COG1064	alcohol dehydrogenase
JCQ35_RS11550	COG2814	Major facilitator Superfamily
JCQ35_RS11585	COG0642	Histidine kinase
JCQ35_RS11600	COG1288	antiporter activity
JCQ35_RS11605	COG3711	transcriptional antiterminator
JCQ35_RS11620	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JCQ35_RS11620	COG1263	PTS System
JCQ35_RS11625	COG2723	6-phospho-beta-galactosidase activity
JCQ35_RS11635	COG2807	transmembrane transport
JCQ35_RS11640	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
JCQ35_RS11660	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JCQ35_RS11665	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
JCQ35_RS11675	COG1609	Transcriptional regulator
JCQ35_RS11680	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
JCQ35_RS11685	COG2610	gluconate transmembrane transporter activity
JCQ35_RS11695	COG0454	-acetyltransferase
JCQ35_RS11730	COG3290	protein histidine kinase activity
JCQ35_RS11735	COG4565	transcriptional regulatory protein
JCQ35_RS11755	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JCQ35_RS11760	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JCQ35_RS11765	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
JCQ35_RS11770	COG0019	diaminopimelate decarboxylase activity
JCQ35_RS11780	COG4264	IucA IucC family
JCQ35_RS11785	COG4264	IucA IucC family
JCQ35_RS11795	COG0702	epimerase
JCQ35_RS11800	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
JCQ35_RS11820	COG2801	Transposase and inactivated derivatives
JCQ35_RS11830	COG1114	Component of the transport system for branched-chain amino acids
JCQ35_RS11840	COG0183	Belongs to the thiolase family
JCQ35_RS11845	COG3425	synthase
JCQ35_RS11855	COG0477	Major facilitator Superfamily
JCQ35_RS11860	COG0584	glycerophosphoryl diester phosphodiesterase
JCQ35_RS11870	COG1846	Transcriptional regulator
JCQ35_RS11885	COG0531	amino acid
JCQ35_RS11890	COG1846	Transcriptional regulator
JCQ35_RS11890	COG1940	carbohydrate kinase activity
JCQ35_RS11895	COG2115	Belongs to the xylose isomerase family
JCQ35_RS11900	COG1070	Carbohydrate kinase
JCQ35_RS11905	COG2814	Major facilitator Superfamily
JCQ35_RS11905	COG0477	Major facilitator Superfamily
JCQ35_RS11915	COG1028	Short-chain dehydrogenase reductase Sdr
JCQ35_RS11920	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
JCQ35_RS11925	COG0157	Belongs to the NadC ModD family
JCQ35_RS11930	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
JCQ35_RS11940	COG1827	regulation of RNA biosynthetic process
JCQ35_RS11950	COG2318	DinB family
JCQ35_RS11955	COG2851	Citrate transporter
JCQ35_RS11960	COG1054	Belongs to the UPF0176 family
JCQ35_RS11980	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
JCQ35_RS12000	COG0083	homoserine kinase activity
JCQ35_RS12005	COG3386	PFAM SMP-30 Gluconolaconase
JCQ35_RS12010	COG1304	FMN binding
JCQ35_RS12030	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JCQ35_RS12035	COG1028	Short-chain dehydrogenase reductase Sdr
JCQ35_RS12045	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JCQ35_RS12045	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JCQ35_RS12045	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JCQ35_RS12050	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JCQ35_RS12050	COG3711	transcriptional antiterminator
JCQ35_RS12060	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JCQ35_RS12075	COG0579	oxidoreductase
JCQ35_RS12085	COG0318	PFAM AMP-dependent synthetase and ligase
JCQ35_RS12090	COG1960	acyl-CoA dehydrogenase activity
JCQ35_RS12095	COG1024	Enoyl-CoA hydratase
JCQ35_RS12095	COG1250	3-hydroxyacyl-CoA dehydrogenase
JCQ35_RS12100	COG0183	Belongs to the thiolase family
JCQ35_RS12105	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
JCQ35_RS12110	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
JCQ35_RS12115	COG3002	Belongs to the UPF0753 family
JCQ35_RS12120	COG0288	reversible hydration of carbon dioxide
JCQ35_RS12125	COG5609	conserved protein (DUF2294)
JCQ35_RS12130	COG1283	sodium-dependent phosphate transmembrane transporter activity
JCQ35_RS12135	COG0673	inositol 2-dehydrogenase activity
JCQ35_RS12145	COG0673	inositol 2-dehydrogenase activity
JCQ35_RS12170	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
JCQ35_RS12185	COG0733	neurotransmitter:sodium symporter activity
JCQ35_RS12190	COG0583	DNA-binding transcription factor activity
JCQ35_RS12195	COG1380	Effector of murein hydrolase LrgA
JCQ35_RS12205	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
JCQ35_RS12210	COG0175	sulfate reduction
JCQ35_RS12215	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
JCQ35_RS12220	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
JCQ35_RS12240	COG0730	response to heat
JCQ35_RS12245	COG2046	Belongs to the sulfate adenylyltransferase family
JCQ35_RS12250	COG0529	Catalyzes the synthesis of activated sulfate
JCQ35_RS12255	COG1510	regulation of RNA biosynthetic process
JCQ35_RS12260	COG1012	belongs to the aldehyde dehydrogenase family
JCQ35_RS12280	COG0659	secondary active sulfate transmembrane transporter activity
JCQ35_RS12290	COG1621	beta-fructofuranosidase activity
JCQ35_RS12300	COG3588	fructose-bisphosphate aldolase
JCQ35_RS12310	COG2190	(PTS) system
JCQ35_RS12310	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JCQ35_RS12310	COG1263	PTS System
JCQ35_RS12320	COG1486	melibiose metabolic process
JCQ35_RS12325	COG2188	Transcriptional regulator
JCQ35_RS12330	COG1247	-acetyltransferase
JCQ35_RS12335	COG0668	transmembrane transport
JCQ35_RS12360	COG2851	Citrate transporter
JCQ35_RS12365	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
JCQ35_RS12380	COG3328	transposase activity
JCQ35_RS12385	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
JCQ35_RS12395	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
JCQ35_RS12400	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JCQ35_RS12405	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JCQ35_RS12415	COG0477	Major facilitator Superfamily
JCQ35_RS12420	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
JCQ35_RS12440	COG2205	protein histidine kinase activity
JCQ35_RS12445	COG0745	RESPONSE REGULATOR receiver
JCQ35_RS12450	COG2311	Membrane
JCQ35_RS12465	COG3961	Belongs to the TPP enzyme family
JCQ35_RS12480	COG1063	alcohol dehydrogenase
JCQ35_RS12490	COG1063	alcohol dehydrogenase
JCQ35_RS12495	COG3775	system Galactitol-specific IIC component
JCQ35_RS12500	COG3414	Phosphotransferase system galactitol-specific IIB component
JCQ35_RS12515	COG0531	amino acid
JCQ35_RS12530	COG1464	Belongs to the NlpA lipoprotein family
JCQ35_RS12535	COG2271	Major facilitator Superfamily
JCQ35_RS12565	COG0531	amino acid
JCQ35_RS12570	COG2130	NADP-dependent
JCQ35_RS12585	COG2188	Transcriptional regulator
JCQ35_RS12590	COG2222	sugar isomerase
JCQ35_RS12600	COG3684	Belongs to the aldolase LacD family
JCQ35_RS12610	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JCQ35_RS12615	COG3715	PTS system
JCQ35_RS12620	COG3716	PTS system mannose fructose sorbose family IID component
JCQ35_RS12645	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
JCQ35_RS12650	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
JCQ35_RS12655	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
JCQ35_RS12675	COG1316	TRANSCRIPTIONal
JCQ35_RS12685	COG3001	Fructosamine kinase
JCQ35_RS12690	COG1396	sequence-specific DNA binding
JCQ35_RS12695	COG2807	transmembrane transport
JCQ35_RS12700	COG1113	amino acid transport
JCQ35_RS12710	COG3620	sequence-specific DNA binding
JCQ35_RS12730	COG0488	(ABC) transporter
JCQ35_RS12745	COG2084	Dehydrogenase
JCQ35_RS12770	COG4336	lyase activity
JCQ35_RS12775	COG3275	phosphorelay sensor kinase activity
JCQ35_RS12780	COG3279	Response regulator of the LytR AlgR family
JCQ35_RS12785	COG1380	Effector of murein hydrolase LrgA
JCQ35_RS12790	COG1346	cytolysis
JCQ35_RS12800	COG3844	kynureninase activity
JCQ35_RS12805	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
JCQ35_RS12815	COG2188	Transcriptional regulator
JCQ35_RS12820	COG2723	6-phospho-beta-galactosidase activity
JCQ35_RS12845	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
JCQ35_RS12850	COG1280	lysine exporter protein (LysE YggA)
JCQ35_RS12855	COG1132	(ABC) transporter
JCQ35_RS12860	COG1132	(ABC) transporter
JCQ35_RS12870	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
JCQ35_RS12875	COG3189	MarR family transcriptional regulator
JCQ35_RS12885	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
JCQ35_RS12890	COG2022	thiamine diphosphate biosynthetic process
JCQ35_RS12900	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
JCQ35_RS12905	COG0352	thiamine-phosphate diphosphorylase activity
JCQ35_RS12915	COG3279	Response regulator of the LytR AlgR family
JCQ35_RS12925	COG1733	regulation of RNA biosynthetic process
JCQ35_RS12930	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
JCQ35_RS12950	COG1380	Effector of murein hydrolase LrgA
JCQ35_RS12960	COG1278	Cold shock
JCQ35_RS12970	COG0833	amino acid
JCQ35_RS12975	COG2040	homocysteine
JCQ35_RS12980	COG1012	belongs to the aldehyde dehydrogenase family
JCQ35_RS12985	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JCQ35_RS13010	COG0656	L-ascorbic acid biosynthetic process
JCQ35_RS13015	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
JCQ35_RS13020	COG3759	membrane
JCQ35_RS13025	COG2409	Drug exporters of the RND superfamily
JCQ35_RS13035	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
JCQ35_RS13040	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JCQ35_RS13040	COG1263	PTS System
JCQ35_RS13045	COG1737	Transcriptional regulator
JCQ35_RS13055	COG1316	TRANSCRIPTIONal
JCQ35_RS13065	COG2207	Transcriptional regulator
JCQ35_RS13085	COG0582	viral genome integration into host DNA
JCQ35_RS13090	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
JCQ35_RS13090	COG2111	Na H antiporter
JCQ35_RS13095	COG2111	Na H antiporter
JCQ35_RS13110	COG1863	multisubunit Na H antiporter MnhE subunit
JCQ35_RS13115	COG2212	antiporter activity
JCQ35_RS13120	COG1320	monovalent cation:proton antiporter activity
JCQ35_RS13130	COG1108	ABC-type Mn2 Zn2 transport systems permease components
JCQ35_RS13140	COG1321	iron dependent repressor
JCQ35_RS13150	COG1686	Belongs to the peptidase S11 family
JCQ35_RS13155	COG1132	(ABC) transporter
JCQ35_RS13160	COG1620	l-lactate permease
JCQ35_RS13165	COG0039	L-malate dehydrogenase activity
JCQ35_RS13180	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
JCQ35_RS13185	COG1120	ATPase activity
JCQ35_RS13190	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JCQ35_RS13195	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JCQ35_RS13210	COG1302	Protein conserved in bacteria
JCQ35_RS13220	COG2801	Transposase and inactivated derivatives
JCQ35_RS13230	COG2814	Major facilitator Superfamily
JCQ35_RS13235	COG3314	Sporulation integral membrane protein YlbJ
JCQ35_RS13240	COG2801	Transposase and inactivated derivatives
JCQ35_RS13250	COG2329	Antibiotic biosynthesis monooxygenase
JCQ35_RS13255	COG0300	oxidoreductase activity
JCQ35_RS13265	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
JCQ35_RS13270	COG2962	Rard protein
JCQ35_RS13285	COG1988	membrane-bound metal-dependent
JCQ35_RS13300	COG1272	protein, Hemolysin III
JCQ35_RS13315	COG1574	metal-dependent hydrolase with the TIM-barrel fold
JCQ35_RS13330	COG2814	Major facilitator Superfamily
JCQ35_RS13335	COG0489	protein tyrosine kinase activity
JCQ35_RS13340	COG2194	sulfuric ester hydrolase activity
JCQ35_RS13405	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
JCQ35_RS13415	COG1937	Protein conserved in bacteria
JCQ35_RS13420	COG2217	Heavy metal translocating P-type atpase
JCQ35_RS13425	COG0586	Pfam SNARE associated Golgi protein
JCQ35_RS13430	COG0456	acetyltransferase
JCQ35_RS13440	COG2514	catechol 2,3-dioxygenase activity
JCQ35_RS13445	COG1119	ATPase activity
JCQ35_RS13470	COG0702	epimerase
JCQ35_RS13485	COG0640	Transcriptional regulator
JCQ35_RS13500	COG0477	Major facilitator Superfamily
JCQ35_RS13520	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
JCQ35_RS13530	COG2205	protein histidine kinase activity
JCQ35_RS13535	COG1136	(ABC) transporter
JCQ35_RS13540	COG0577	efflux transmembrane transporter activity
JCQ35_RS13545	COG1392	Phosphate transport regulator
JCQ35_RS13550	COG0306	phosphate transporter
JCQ35_RS13555	COG1388	LysM domain
JCQ35_RS13555	COG3942	CHAP domain
JCQ35_RS13560	COG0670	Belongs to the BI1 family
JCQ35_RS13565	COG0217	transcriptional regulatory protein
JCQ35_RS13575	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
JCQ35_RS13595	COG1566	PFAM secretion protein HlyD family protein
JCQ35_RS13600	COG2814	Major facilitator Superfamily
JCQ35_RS13615	COG0583	DNA-binding transcription factor activity
JCQ35_RS13620	COG2258	MOSC domain
JCQ35_RS13630	COG2839	Protein conserved in bacteria
JCQ35_RS13640	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
JCQ35_RS13650	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
JCQ35_RS13655	COG1447	Phosphotransferase system cellobiose-specific component IIA
JCQ35_RS13660	COG4221	oxidoreductase activity
JCQ35_RS13665	COG0788	formyltetrahydrofolate deformylase activity
JCQ35_RS13670	COG0598	Magnesium transport protein CorA
JCQ35_RS13675	COG1940	carbohydrate kinase activity
JCQ35_RS13685	COG3328	transposase activity
JCQ35_RS13695	COG0778	Nitroreductase
JCQ35_RS13705	COG2814	Major facilitator Superfamily
JCQ35_RS13710	COG1733	regulation of RNA biosynthetic process
JCQ35_RS13715	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
JCQ35_RS13740	COG1757	Na H antiporter
JCQ35_RS13745	COG0004	ammonium transporteR
JCQ35_RS13750	COG1473	amidohydrolase
JCQ35_RS13760	COG2814	Major facilitator Superfamily
JCQ35_RS13765	COG0753	catalase activity
JCQ35_RS13780	COG3048	D-serine ammonia-lyase activity
JCQ35_RS13790	COG1966	Carbon starvation protein
JCQ35_RS13795	COG3383	formate dehydrogenase (NAD+) activity
JCQ35_RS13815	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
JCQ35_RS13825	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
JCQ35_RS13830	COG2011	ABC-type metal ion transport system permease component
JCQ35_RS13835	COG1464	Belongs to the NlpA lipoprotein family
JCQ35_RS13850	COG3942	CHAP domain
JCQ35_RS13855	COG1757	Na H antiporter
JCQ35_RS13860	COG3942	CHAP domain
JCQ35_RS13925	COG1131	(ABC) transporter
JCQ35_RS13930	COG1823	symporter activity
JCQ35_RS13935	COG1960	acyl-CoA dehydrogenase activity
JCQ35_RS13940	COG0697	spore germination
JCQ35_RS13945	COG2832	Protein of unknown function (DUF454)
JCQ35_RS13950	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
JCQ35_RS13970	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
JCQ35_RS13980	COG2186	Transcriptional regulator
JCQ35_RS13985	COG2186	Transcriptional regulator
JCQ35_RS13995	COG1268	BioY protein
JCQ35_RS14005	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
JCQ35_RS14010	COG3383	formate dehydrogenase (NAD+) activity
JCQ35_RS14020	COG4149	molybdate abc transporter
JCQ35_RS14025	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
JCQ35_RS14030	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
JCQ35_RS14055	COG0640	Transcriptional regulator
JCQ35_RS14060	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
JCQ35_RS14065	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
JCQ35_RS14125	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
JCQ35_RS14180	COG0726	polysaccharide deacetylase
JCQ35_RS14220	COG1192	Involved in chromosome partitioning