locus-tag	class	description
AL483_RS08255	COG0346	lactoylglutathione lyase activity
AL483_RS10085	COG2211	Major facilitator Superfamily
AL483_RS10125	COG2207	Transcriptional regulator
AL483_RS10230	COG3250	beta-galactosidase activity
AL483_RS11280	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
AL483_RS11295	COG1129	ABC transporter
AL483_RS11440	COG0586	Pfam SNARE associated Golgi protein
AL483_RS11445	COG2271	Major facilitator Superfamily
AL483_RS11575	COG3527	Alpha-acetolactate decarboxylase
AL483_RS12760	COG1289	transmembrane transporter activity
AL483_RS12765	COG4876	unkown
AL483_RS12770	COG0523	cobalamin synthesis protein
AL483_RS12775	COG2357	RelA SpoT domain protein
AL483_RS12785	COG1802	Transcriptional regulator
AL483_RS12795	COG2610	gluconate transmembrane transporter activity
AL483_RS12805	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AL483_RS12810	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
AL483_RS12835	COG4619	ABC transporter
AL483_RS12840	COG0390	transport system, permease component
AL483_RS12845	COG2814	Major facilitator Superfamily
AL483_RS12850	COG2272	Belongs to the type-B carboxylesterase lipase family
AL483_RS12855	COG0531	amino acid
AL483_RS12860	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
AL483_RS12870	COG1174	glycine betaine transport
AL483_RS12880	COG1174	glycine betaine transport
AL483_RS12890	COG1309	transcriptional regulator
AL483_RS12905	COG1346	cytolysis
AL483_RS12910	COG1380	Effector of murein hydrolase LrgA
AL483_RS12915	COG3279	Response regulator of the LytR AlgR family
AL483_RS12920	COG3275	phosphorelay sensor kinase activity
AL483_RS12930	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AL483_RS12940	COG1113	amino acid transport
AL483_RS12950	COG2814	Major facilitator Superfamily
AL483_RS12960	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
AL483_RS12965	COG0588	phosphoglycerate mutase activity
AL483_RS12975	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL483_RS12980	COG0765	amino acid transport
AL483_RS12985	COG1126	abc transporter atp-binding protein
AL483_RS13025	COG2116	formate transmembrane transporter activity
AL483_RS13040	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AL483_RS13050	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AL483_RS13050	COG1648	precorrin-2 dehydrogenase activity
AL483_RS13060	COG1140	nitrate reductase beta subunit
AL483_RS13070	COG2181	nitrate reductase activity
AL483_RS13080	COG4585	Histidine kinase
AL483_RS13085	COG2197	response regulator
AL483_RS13090	COG2223	nitrite transmembrane transporter activity
AL483_RS13095	COG0772	Belongs to the SEDS family
AL483_RS13100	COG3425	synthase
AL483_RS13120	COG1846	Transcriptional regulator
AL483_RS13125	COG0778	Nitroreductase
AL483_RS13135	COG0697	spore germination
AL483_RS13140	COG1301	dicarboxylic acid transport
AL483_RS13150	COG1611	Belongs to the LOG family
AL483_RS13170	COG0492	ferredoxin-NADP+ reductase activity
AL483_RS13175	COG2814	Major facilitator Superfamily
AL483_RS13180	COG0604	alcohol dehydrogenase
AL483_RS13190	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
AL483_RS13195	COG1620	l-lactate permease
AL483_RS13200	COG0438	transferase activity, transferring glycosyl groups
AL483_RS13210	COG5002	protein histidine kinase activity
AL483_RS13210	COG3850	Histidine kinase
AL483_RS13215	COG0745	RESPONSE REGULATOR receiver
AL483_RS13220	COG0577	efflux transmembrane transporter activity
AL483_RS13245	COG2814	Major facilitator Superfamily
AL483_RS13255	COG1566	PFAM secretion protein HlyD family protein
AL483_RS13260	COG2814	Major facilitator Superfamily
AL483_RS13265	COG1033	growth of symbiont in host cell
AL483_RS13265	COG2409	Drug exporters of the RND superfamily
AL483_RS13285	COG0598	Magnesium transport protein CorA
AL483_RS13290	COG1304	FMN binding
AL483_RS13305	COG0602	queuosine metabolic process
AL483_RS13310	COG2094	Belongs to the DNA glycosylase MPG family
AL483_RS13315	COG3152	Membrane
AL483_RS13340	COG1668	transmembrane transport
AL483_RS13345	COG1742	UPF0060 membrane protein
AL483_RS13350	COG2017	converts alpha-aldose to the beta-anomer
AL483_RS13365	COG0010	Belongs to the arginase family
AL483_RS13370	COG0583	DNA-binding transcription factor activity
AL483_RS13375	COG3314	Sporulation integral membrane protein YlbJ
AL483_RS13380	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
AL483_RS13385	COG1228	amidohydrolase
AL483_RS13390	COG0659	secondary active sulfate transmembrane transporter activity
AL483_RS13395	COG1473	amidohydrolase
AL483_RS13400	COG1028	Short-chain dehydrogenase reductase Sdr
AL483_RS13405	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AL483_RS13420	COG2271	Major facilitator Superfamily
AL483_RS13430	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AL483_RS13455	COG1113	amino acid transport
AL483_RS13460	COG1737	Transcriptional regulator
AL483_RS13485	COG1316	TRANSCRIPTIONal
AL483_RS13495	COG3383	formate dehydrogenase (NAD+) activity
AL483_RS13520	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AL483_RS13525	COG2076	Multidrug Resistance protein
AL483_RS13530	COG2076	Multidrug Resistance protein
AL483_RS13545	COG1757	Na H antiporter
AL483_RS13555	COG3942	CHAP domain
AL483_RS13570	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AL483_RS13570	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AL483_RS13595	COG0829	nickel cation binding
AL483_RS13605	COG0830	nickel cation binding
AL483_RS13610	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
AL483_RS13615	COG0804	urea catabolic process
AL483_RS13620	COG0832	Belongs to the urease beta subunit family
AL483_RS13625	COG0831	urea catabolic process
AL483_RS13635	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AL483_RS13640	COG1960	acyl-CoA dehydrogenase activity
AL483_RS13645	COG1957	nucleoside hydrolase
AL483_RS13650	COG1268	BioY protein
AL483_RS13660	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
AL483_RS13665	COG1609	Transcriptional regulator
AL483_RS13670	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
AL483_RS13675	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AL483_RS13680	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
AL483_RS13685	COG0725	ABC transporter, periplasmic molybdate-binding protein
AL483_RS13690	COG4149	molybdate abc transporter
AL483_RS13695	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
AL483_RS13700	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AL483_RS13705	COG0521	Mo-molybdopterin cofactor biosynthetic process
AL483_RS13710	COG0315	cyclic pyranopterin monophosphate synthase activity
AL483_RS13715	COG0303	'Molybdopterin
AL483_RS13725	COG0314	molybdopterin synthase activity
AL483_RS13735	COG0746	molybdenum cofactor guanylyltransferase activity
AL483_RS13740	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AL483_RS13750	COG1131	(ABC) transporter
AL483_RS13755	COG0842	Transport permease protein
AL483_RS13765	COG2197	response regulator
AL483_RS13770	COG2814	Major facilitator Superfamily
AL483_RS13790	COG2348	transferase activity, transferring amino-acyl groups
AL483_RS13795	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AL483_RS13820	COG4975	Glucose uptake
AL483_RS13835	COG2252	PERMEase
AL483_RS13850	COG0051	transcription antitermination factor activity, RNA binding
AL483_RS13855	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
AL483_RS13860	COG0088	Forms part of the polypeptide exit tunnel
AL483_RS13865	COG0089	rRNA binding
AL483_RS13870	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AL483_RS13875	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AL483_RS13880	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
AL483_RS13885	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
AL483_RS13890	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
AL483_RS13900	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
AL483_RS13905	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
AL483_RS13910	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
AL483_RS13915	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
AL483_RS13920	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
AL483_RS13925	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
AL483_RS13930	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
AL483_RS13935	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
AL483_RS13940	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
AL483_RS13945	COG1841	ribosomal large subunit assembly
AL483_RS13950	COG0200	Binds to the 23S rRNA
AL483_RS13955	COG0201	protein transport
AL483_RS13960	COG0563	adenylate kinase activity
AL483_RS13970	COG0257	Belongs to the bacterial ribosomal protein bL36 family
AL483_RS13975	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
AL483_RS13980	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
AL483_RS13985	COG0202	RNA polymerase activity
AL483_RS13990	COG0203	ribosomal protein L17
AL483_RS14010	COG0101	tRNA pseudouridine synthase activity
AL483_RS14015	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
AL483_RS14020	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
AL483_RS14025	COG1442	glycosyl transferase family 8
AL483_RS14050	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
AL483_RS14050	COG2213	PTS system mannitol-specific
AL483_RS14055	COG2318	DinB family
AL483_RS14060	COG2608	mercury ion transmembrane transporter activity
AL483_RS14070	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AL483_RS14075	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AL483_RS14075	COG0574	Belongs to the PEP-utilizing enzyme family
AL483_RS14080	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
AL483_RS14085	COG2130	NADP-dependent
AL483_RS14095	COG2130	NADP-dependent
AL483_RS14100	COG0604	alcohol dehydrogenase
AL483_RS14105	COG0604	alcohol dehydrogenase
AL483_RS14110	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AL483_RS14125	COG1302	Protein conserved in bacteria
AL483_RS14135	COG2814	Major facilitator Superfamily
AL483_RS14140	COG4264	IucA IucC family
AL483_RS14145	COG3457	Alanine racemase
AL483_RS14150	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
AL483_RS14155	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AL483_RS14160	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AL483_RS14165	COG3314	Sporulation integral membrane protein YlbJ
AL483_RS14170	COG2329	Antibiotic biosynthesis monooxygenase
AL483_RS14185	COG1988	membrane-bound metal-dependent
AL483_RS14190	COG4284	Utp--glucose-1-phosphate uridylyltransferase
AL483_RS14195	COG1272	protein, Hemolysin III
AL483_RS14210	COG2814	Major facilitator Superfamily
AL483_RS14215	COG0489	protein tyrosine kinase activity
AL483_RS14265	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
AL483_RS14270	COG4856	YbbR-like protein
AL483_RS14275	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AL483_RS14280	COG0246	Mannitol dehydrogenase
AL483_RS14285	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
AL483_RS14290	COG3711	transcriptional antiterminator
AL483_RS14300	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AL483_RS14325	COG0640	Transcriptional regulator
AL483_RS14330	COG0702	epimerase
AL483_RS14335	COG2186	Transcriptional regulator
AL483_RS14340	COG0247	lactate metabolic process
AL483_RS14345	COG1139	Iron-sulfur cluster binding protein
AL483_RS14350	COG1556	Lactate utilization protein
AL483_RS14355	COG1482	cell wall glycoprotein biosynthetic process
AL483_RS14375	COG0783	Belongs to the Dps family
AL483_RS14380	COG1876	peptidase activity
AL483_RS14385	COG0813	purine-nucleoside phosphorylase activity
AL483_RS14390	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
AL483_RS14400	COG1854	S-ribosylhomocysteine lyase activity
AL483_RS14425	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AL483_RS14430	COG3343	RNA polymerase activity
AL483_RS14435	COG0504	CTP synthase activity
AL483_RS14445	COG0191	fructose-bisphosphate aldolase activity
AL483_RS14450	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AL483_RS14455	COG1733	regulation of RNA biosynthetic process
AL483_RS14460	COG1012	belongs to the aldehyde dehydrogenase family
AL483_RS14465	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
AL483_RS14470	COG0254	rRNA binding
AL483_RS14475	COG1435	thymidine kinase activity
AL483_RS14480	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
AL483_RS14485	COG2890	protein-(glutamine-N5) methyltransferase activity
AL483_RS14490	COG0009	L-threonylcarbamoyladenylate synthase
AL483_RS14495	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AL483_RS14500	COG4475	Protein of unknown function (DUF436)
AL483_RS14505	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AL483_RS14510	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
AL483_RS14515	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
AL483_RS14525	COG0356	it plays a direct role in the translocation of protons across the membrane
AL483_RS14530	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AL483_RS14535	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AL483_RS14540	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AL483_RS14545	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
AL483_RS14550	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
AL483_RS14555	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
AL483_RS14560	COG0355	proton-transporting ATP synthase activity, rotational mechanism
AL483_RS14570	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AL483_RS14580	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AL483_RS14590	COG0629	single-stranded DNA binding
AL483_RS14595	COG1388	LysM domain
AL483_RS14605	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
AL483_RS14615	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
AL483_RS14620	COG0352	thiamine-phosphate diphosphorylase activity
AL483_RS14625	COG0706	membrane insertase activity
AL483_RS14630	COG0456	acetyltransferase
AL483_RS14635	COG1418	mRNA catabolic process
AL483_RS14640	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AL483_RS14645	COG1937	Protein conserved in bacteria
AL483_RS14660	COG2217	Heavy metal translocating P-type atpase
AL483_RS14670	COG0772	Belongs to the SEDS family
AL483_RS14675	COG1181	Belongs to the D-alanine--D-alanine ligase family
AL483_RS14680	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AL483_RS14685	COG0513	Belongs to the DEAD box helicase family
AL483_RS14700	COG3402	PFAM membrane-flanked domain
AL483_RS14705	COG0736	holo-[acyl-carrier-protein] synthase activity
AL483_RS14710	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AL483_RS14725	COG2208	phosphoserine phosphatase activity
AL483_RS14740	COG1191	sigma factor activity
AL483_RS14745	COG2183	response to ionizing radiation
AL483_RS14750	COG3091	SprT-like family
AL483_RS14775	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AL483_RS14785	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
AL483_RS14790	COG0473	3-isopropylmalate dehydrogenase activity
AL483_RS14795	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AL483_RS14800	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
AL483_RS14810	COG0028	Belongs to the TPP enzyme family
AL483_RS14815	COG0129	dihydroxy-acid dehydratase activity
AL483_RS14820	COG0802	atpase or kinase
AL483_RS14825	COG1214	PFAM Peptidase M22, glycoprotease
AL483_RS14830	COG0456	acetyltransferase
AL483_RS14835	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
AL483_RS14840	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
AL483_RS14845	COG0488	(ABC) transporter
AL483_RS14850	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
AL483_RS14855	COG0425	Belongs to the sulfur carrier protein TusA family
AL483_RS14860	COG2391	methyltransferase activity
AL483_RS14865	COG1621	beta-fructofuranosidase activity
AL483_RS14885	COG4512	PFAM Accessory gene regulator B
AL483_RS14910	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
AL483_RS14915	COG0459	protein refolding
AL483_RS14935	COG1725	Transcriptional regulator
AL483_RS14950	COG1131	(ABC) transporter
AL483_RS14980	COG1136	(ABC) transporter
AL483_RS15040	COG3682	Transcriptional regulator
AL483_RS15050	COG2706	6-phosphogluconolactonase activity
AL483_RS15055	COG0471	metal ion transport
AL483_RS15065	COG1335	isochorismatase
AL483_RS15070	COG1227	inorganic diphosphatase activity
AL483_RS15075	COG1012	belongs to the aldehyde dehydrogenase family
AL483_RS15080	COG0077	Prephenate dehydratase
AL483_RS15090	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
AL483_RS15095	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
AL483_RS15100	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
AL483_RS15110	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AL483_RS15115	COG4496	protein, YerC YecD
AL483_RS15120	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
AL483_RS15130	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AL483_RS15135	COG4851	CamS sex pheromone cAM373 precursor
AL483_RS15145	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AL483_RS15150	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AL483_RS15155	COG0154	amidase activity
AL483_RS15160	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AL483_RS15165	COG1597	lipid kinase activity
AL483_RS15170	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AL483_RS15175	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AL483_RS15195	COG4129	membrane
AL483_RS15200	COG0024	Methionine aminopeptidase
AL483_RS15220	COG2197	response regulator
AL483_RS15225	COG0288	reversible hydration of carbon dioxide
AL483_RS15230	COG1295	ribonuclease BN
AL483_RS15245	COG4840	Belongs to the UPF0435 family
AL483_RS15250	COG2309	aminopeptidase activity
AL483_RS15255	COG1607	acyl-coa hydrolase
AL483_RS15260	COG0535	radical SAM domain protein
AL483_RS15265	COG0693	protein deglycase activity
AL483_RS15270	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AL483_RS15275	COG2137	regulation of response to DNA damage stimulus
AL483_RS15285	COG1134	teichoic acid transport
AL483_RS15285	COG1388	LysM domain
AL483_RS15295	COG1988	membrane-bound metal-dependent
AL483_RS15300	COG1194	a g-specific adenine glycosylase
AL483_RS15305	COG3557	Belongs to the UPF0374 family
AL483_RS15315	COG4129	membrane
AL483_RS15320	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
AL483_RS15325	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AL483_RS15330	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AL483_RS15335	COG0735	belongs to the Fur family
AL483_RS15490	COG0765	amino acid transport
AL483_RS15495	COG1126	abc transporter atp-binding protein
AL483_RS15500	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AL483_RS15505	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AL483_RS15515	COG0363	glucosamine-6-phosphate deaminase activity
AL483_RS15525	COG0114	fumarate hydratase activity
AL483_RS15530	COG0564	pseudouridine synthase activity
AL483_RS15535	COG2203	Gaf domain
AL483_RS15535	COG4585	Histidine kinase
AL483_RS15540	COG2197	response regulator
AL483_RS15555	COG4399	Belongs to the UPF0754 family
AL483_RS15565	COG0420	3'-5' exonuclease activity
AL483_RS15575	COG3481	metal-dependent phosphohydrolase, HD sub domain
AL483_RS15580	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AL483_RS15595	COG0537	adenosine 5'-monophosphoramidase activity
AL483_RS15600	COG1131	(ABC) transporter
AL483_RS15615	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
AL483_RS15620	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
AL483_RS15625	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
AL483_RS15635	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
AL483_RS15640	COG0157	Belongs to the NadC ModD family
AL483_RS15645	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
AL483_RS15655	COG1827	regulation of RNA biosynthetic process
AL483_RS15720	COG0318	PFAM AMP-dependent synthetase and ligase
AL483_RS15730	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
AL483_RS15735	COG0494	nUDIX hydrolase
AL483_RS15740	COG1506	peptidase
AL483_RS15745	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
AL483_RS15750	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
AL483_RS15760	COG0656	L-ascorbic acid biosynthetic process
AL483_RS15765	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AL483_RS15780	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AL483_RS15795	COG1595	DNA-templated transcription, initiation
AL483_RS15805	COG3266	domain, Protein
AL483_RS15805	COG4193	domain, Protein
AL483_RS15805	COG5632	N-Acetylmuramoyl-L-alanine amidase
AL483_RS15815	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AL483_RS15815	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AL483_RS15820	COG0307	riboflavin synthase, alpha
AL483_RS15830	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
AL483_RS15840	COG2267	carboxylic ester hydrolase activity
AL483_RS15845	COG0039	L-malate dehydrogenase activity
AL483_RS15850	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
AL483_RS15855	COG1242	4 iron, 4 sulfur cluster binding
AL483_RS15860	COG2814	Major facilitator Superfamily
AL483_RS15870	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AL483_RS15875	COG2081	HI0933 family
AL483_RS15880	COG2244	polysaccharide biosynthetic process
AL483_RS15885	COG1187	pseudouridine synthase activity
AL483_RS15895	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AL483_RS15905	COG0510	thiamine kinase activity
AL483_RS15910	COG0220	tRNA (guanine-N7-)-methyltransferase activity
AL483_RS15915	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AL483_RS15925	COG1363	Peptidase, m42
AL483_RS15930	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AL483_RS15935	COG4848	Belongs to the UPF0354 family
AL483_RS15940	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AL483_RS15945	COG1674	ftsk spoiiie
AL483_RS15950	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AL483_RS15955	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
AL483_RS15965	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
AL483_RS15965	COG1605	Chorismate mutase
AL483_RS15970	COG1609	Transcriptional regulator
AL483_RS15980	COG0454	-acetyltransferase
AL483_RS15985	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AL483_RS15990	COG2759	Belongs to the formate--tetrahydrofolate ligase family
AL483_RS16000	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AL483_RS16005	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AL483_RS16010	COG0204	Acyl-transferase
AL483_RS16015	COG1263	PTS System
AL483_RS16015	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AL483_RS16025	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AL483_RS16030	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
AL483_RS16035	COG1764	response to oxidative stress
AL483_RS16040	COG0584	glycerophosphoryl diester phosphodiesterase
AL483_RS16050	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
AL483_RS16055	COG1956	GAF domain-containing protein
AL483_RS16060	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
AL483_RS16065	COG1104	cysteine desulfurase activity
AL483_RS16070	COG0301	tRNA thio-modification
AL483_RS16075	COG0730	response to heat
AL483_RS16080	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
AL483_RS16085	COG0827	DNA restriction-modification system
AL483_RS16090	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AL483_RS16100	COG0589	response to stress
AL483_RS16110	COG0006	proline dipeptidase activity
AL483_RS16115	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
AL483_RS16125	COG4109	DRTGG domain
AL483_RS16130	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
AL483_RS16135	COG0587	DNA-directed DNA polymerase activity
AL483_RS16140	COG0281	malic enzyme
AL483_RS16145	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
AL483_RS16150	COG0825	malonyl-CoA metabolic process
AL483_RS16155	COG0205	6-phosphofructokinase activity
AL483_RS16160	COG0469	pyruvate kinase activity
AL483_RS16165	COG1113	amino acid transport
AL483_RS16170	COG0372	Belongs to the citrate synthase family
AL483_RS16175	COG0538	isocitrate dehydrogenase activity
AL483_RS16180	COG0745	RESPONSE REGULATOR receiver
AL483_RS16185	COG5002	protein histidine kinase activity
AL483_RS16190	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AL483_RS16190	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AL483_RS16200	COG0237	dephospho-CoA kinase activity
AL483_RS16210	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
AL483_RS16220	COG1484	DNA-dependent DNA replication
AL483_RS16225	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AL483_RS16230	COG0833	amino acid
AL483_RS16235	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
AL483_RS16240	COG0291	Belongs to the bacterial ribosomal protein bL35 family
AL483_RS16245	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
AL483_RS16250	COG4112	unkown
AL483_RS16260	COG0544	peptidyl-prolyl cis-trans isomerase activity
AL483_RS16265	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
AL483_RS16270	COG0218	Necessary for normal cell division and for the maintenance of normal septation
AL483_RS16275	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
AL483_RS16280	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AL483_RS16285	COG0181	hydroxymethylbilane synthase activity
AL483_RS16300	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
AL483_RS16310	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
AL483_RS16325	COG2818	Glycosylase
AL483_RS16330	COG0525	valine-tRNA ligase activity
AL483_RS16335	COG0285	dihydrofolate synthase activity
AL483_RS16350	COG2003	Belongs to the UPF0758 family
AL483_RS16375	COG2868	ribosomal protein
AL483_RS16385	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AL483_RS16390	COG4492	Belongs to the UPF0735 family
AL483_RS16395	COG0632	four-way junction helicase activity
AL483_RS16400	COG2255	four-way junction helicase activity
AL483_RS16410	COG0343	queuine tRNA-ribosyltransferase activity
AL483_RS16415	COG1862	Preprotein translocase
AL483_RS16420	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AL483_RS16420	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AL483_RS16425	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
AL483_RS16425	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
AL483_RS16430	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AL483_RS16440	COG1490	D-aminoacyl-tRNA deacylase activity
AL483_RS16445	COG0860	N-Acetylmuramoyl-L-alanine amidase
AL483_RS16450	COG0124	histidyl-tRNA synthetase
AL483_RS16455	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
AL483_RS16465	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
AL483_RS16470	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AL483_RS16475	COG1959	2 iron, 2 sulfur cluster binding
AL483_RS16485	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AL483_RS16490	COG1104	cysteine desulfurase activity
AL483_RS16495	COG0482	sulfurtransferase activity
AL483_RS16505	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AL483_RS16510	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AL483_RS16515	COG4472	Bacterial protein of unknown function (DUF965)
AL483_RS16520	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
AL483_RS16530	COG4122	O-methyltransferase activity
AL483_RS16535	COG0826	peptidase U32
AL483_RS16540	COG0826	peptidase U32
AL483_RS16545	COG0572	uridine kinase
AL483_RS16550	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AL483_RS16555	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AL483_RS16560	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
AL483_RS16565	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
AL483_RS16570	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AL483_RS16575	COG1534	Rna-binding protein
AL483_RS16585	COG1713	HD superfamily hydrolase involved in NAD metabolism
AL483_RS16590	COG0799	negative regulation of ribosome biogenesis
AL483_RS16600	COG1596	polysaccharide export
AL483_RS16600	COG1555	photosystem II stabilization
AL483_RS16605	COG2131	deaminase
AL483_RS16610	COG2333	competence protein COMEC
AL483_RS16610	COG0658	competence protein
AL483_RS16615	COG1466	dna polymerase III delta subunit
AL483_RS16625	COG0268	Binds directly to 16S ribosomal RNA
AL483_RS16630	COG0481	GTPase activity
AL483_RS16635	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AL483_RS16640	COG1420	regulation of RNA biosynthetic process
AL483_RS16645	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AL483_RS16650	COG0443	Heat shock 70 kDa protein
AL483_RS16655	COG0484	heat shock protein binding
AL483_RS16660	COG2264	protein methyltransferase activity
AL483_RS16665	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AL483_RS16670	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AL483_RS16685	COG4864	UPF0365 protein
AL483_RS16695	COG1702	phosphate starvation-inducible protein PhoH
AL483_RS16700	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
AL483_RS16705	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
AL483_RS16715	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
AL483_RS16720	COG1381	Involved in DNA repair and RecF pathway recombination
AL483_RS16725	COG0423	glycine-tRNA ligase activity
AL483_RS16730	COG0517	IMP dehydrogenase activity
AL483_RS16735	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
AL483_RS16745	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AL483_RS16750	COG2384	SAM-dependent methyltransferase
AL483_RS16760	COG0513	Belongs to the DEAD box helicase family
AL483_RS16765	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
AL483_RS16770	COG1121	(ABC) transporter
AL483_RS16775	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AL483_RS16780	COG0735	belongs to the Fur family
AL483_RS16790	COG0768	penicillin binding
AL483_RS16795	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AL483_RS16805	COG4483	Protein conserved in bacteria
AL483_RS16810	COG1940	carbohydrate kinase activity
AL483_RS16815	COG0011	TIGRFAM Protein of
AL483_RS16825	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AL483_RS16830	COG1459	type II secretion system
AL483_RS16835	COG4537	Required for transformation and DNA binding
AL483_RS16860	COG0404	The glycine cleavage system catalyzes the degradation of glycine
AL483_RS16865	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AL483_RS16870	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AL483_RS16875	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AL483_RS16880	COG0095	Lipoate-protein ligase
AL483_RS16895	COG0006	proline dipeptidase activity
AL483_RS16900	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AL483_RS16905	COG0511	ligase activity, forming carbon-carbon bonds
AL483_RS16910	COG0439	Biotin carboxylase
AL483_RS16920	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AL483_RS16925	COG1570	exodeoxyribonuclease VII activity
AL483_RS16930	COG1722	exodeoxyribonuclease VII activity
AL483_RS16940	COG1438	arginine binding
AL483_RS16945	COG0497	DNA recombination
AL483_RS16950	COG0280	phosphate acetyltransferase
AL483_RS16960	COG3426	butyrate kinase activity
AL483_RS16965	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AL483_RS16970	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AL483_RS16975	COG0022	dehydrogenase e1 component
AL483_RS16980	COG0508	dehydrogenase complex catalyzes the overall conversion of
AL483_RS16990	COG4129	membrane
AL483_RS16995	COG2195	Cleaves the N-terminal amino acid of tripeptides
AL483_RS17010	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
AL483_RS17015	COG1234	tRNA 3'-trailer cleavage
AL483_RS17020	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AL483_RS17030	COG0667	Aldo Keto reductase
AL483_RS17040	COG0735	belongs to the Fur family
AL483_RS17045	COG4974	Belongs to the 'phage' integrase family
AL483_RS17055	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
AL483_RS17060	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
AL483_RS17065	COG1187	pseudouridine synthase activity
AL483_RS17070	COG0745	RESPONSE REGULATOR receiver
AL483_RS17085	COG1141	Ferredoxin
AL483_RS17095	COG0514	ATP-dependent DNA helicase (RecQ)
AL483_RS17105	COG0492	ferredoxin-NADP+ reductase activity
AL483_RS17115	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
AL483_RS17125	COG1160	GTP binding
AL483_RS17130	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
AL483_RS17145	COG2226	methyltransferase
AL483_RS17150	COG0142	geranyltranstransferase activity
AL483_RS17155	COG0105	UTP biosynthetic process
AL483_RS17160	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
AL483_RS17165	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
AL483_RS17170	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
AL483_RS17180	COG5582	Belongs to the UPF0302 family
AL483_RS17185	COG4347	Protein of unknown function (DUF1405)
AL483_RS17190	COG2738	Putative neutral zinc metallopeptidase
AL483_RS17195	COG1694	Mazg nucleotide pyrophosphohydrolase
AL483_RS17200	COG0438	transferase activity, transferring glycosyl groups
AL483_RS17205	COG0617	tRNA 3'-terminal CCA addition
AL483_RS17215	COG1199	ATP-dependent helicase activity
AL483_RS17215	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AL483_RS17220	COG0017	Asparaginyl-tRNA synthetase
AL483_RS17225	COG3935	DnaD domain protein
AL483_RS17230	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AL483_RS17240	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AL483_RS17240	COG4499	WXG100 protein secretion system (Wss), protein YukC
AL483_RS17245	COG3331	DNA recombination
AL483_RS17255	COG4474	Belongs to the UPF0398 family
AL483_RS17260	COG3599	regulation of cell shape
AL483_RS17270	COG0116	Belongs to the methyltransferase superfamily
AL483_RS17275	COG2962	Rard protein
AL483_RS17280	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
AL483_RS17285	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AL483_RS17290	COG0328	RNA-DNA hybrid ribonuclease activity
AL483_RS17295	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
AL483_RS17305	COG1413	lyase activity
AL483_RS17335	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AL483_RS17340	COG2190	(PTS) system
AL483_RS17360	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AL483_RS17365	COG0671	phosphoesterase, PA-phosphatase related
AL483_RS17370	COG0745	RESPONSE REGULATOR receiver
AL483_RS17375	COG5002	protein histidine kinase activity
AL483_RS17380	COG0567	Dehydrogenase, E1 component
AL483_RS17405	COG0714	Associated with various cellular activities
AL483_RS17410	COG4548	von Willebrand factor, type A
AL483_RS17415	COG1114	Component of the transport system for branched-chain amino acids
AL483_RS17420	COG1597	lipid kinase activity
AL483_RS17425	COG3853	Toxic anion resistance protein (TelA)
AL483_RS17445	COG1278	Cold shock
AL483_RS17465	COG1473	amidohydrolase
AL483_RS17475	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
AL483_RS17480	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AL483_RS17485	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AL483_RS17495	COG0488	(ABC) transporter
AL483_RS17500	COG2996	Protein conserved in bacteria
AL483_RS17505	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AL483_RS17510	COG0573	inorganic phosphate transmembrane transporter activity
AL483_RS17515	COG0581	inorganic phosphate transmembrane transporter activity
AL483_RS17520	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AL483_RS17525	COG0704	Plays a role in the regulation of phosphate uptake
AL483_RS17530	COG1164	Oligoendopeptidase f
AL483_RS17540	COG0747	negative chemotaxis
AL483_RS17570	COG2348	transferase activity, transferring amino-acyl groups
AL483_RS17575	COG2348	transferase activity, transferring amino-acyl groups
AL483_RS17580	COG0159	tryptophan synthase activity
AL483_RS17585	COG0133	tryptophan synthase activity
AL483_RS17590	COG0135	phosphoribosylanthranilate isomerase activity
AL483_RS17595	COG0134	indole-3-glycerol-phosphate synthase activity
AL483_RS17600	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AL483_RS17605	COG0512	Glutamine amidotransferase of anthranilate synthase
AL483_RS17610	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AL483_RS17615	COG1363	Peptidase, m42
AL483_RS17620	COG0287	Prephenate dehydrogenase
AL483_RS17625	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AL483_RS17645	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
AL483_RS17660	COG0628	permease
AL483_RS17665	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AL483_RS17665	COG1263	PTS System
AL483_RS17665	COG2190	(PTS) system
AL483_RS17670	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AL483_RS17670	COG1263	PTS System
AL483_RS17670	COG2190	(PTS) system
AL483_RS17675	COG3711	transcriptional antiterminator
AL483_RS17680	COG1115	amino acid carrier protein
AL483_RS17685	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AL483_RS17700	COG4841	protein insertion into membrane
AL483_RS17710	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AL483_RS17715	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AL483_RS17720	COG1970	mechanosensitive ion channel activity
AL483_RS17730	COG0420	3'-5' exonuclease activity
AL483_RS17735	COG4846	Membrane protein involved in cytochrome C biogenesis
AL483_RS17740	COG3763	UPF0154 protein
AL483_RS17745	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AL483_RS17750	COG4224	UPF0291 protein
AL483_RS17760	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AL483_RS17770	COG2249	NAD(P)H dehydrogenase (quinone) activity
AL483_RS17780	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AL483_RS17785	COG1621	beta-fructofuranosidase activity
AL483_RS17790	COG1609	Transcriptional regulator
AL483_RS17795	COG2340	Cysteine-rich secretory protein family
AL483_RS17800	COG0516	GMP reductase activity
AL483_RS17805	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
AL483_RS17815	COG0833	amino acid
AL483_RS17830	COG0083	homoserine kinase activity
AL483_RS17835	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
AL483_RS17840	COG0460	homoserine dehydrogenase
AL483_RS17845	COG0527	aspartate kinase activity
AL483_RS17870	COG1525	nuclease
AL483_RS17880	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AL483_RS17885	COG0789	Transcriptional regulator
AL483_RS17900	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
AL483_RS17905	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AL483_RS17910	COG0386	Belongs to the glutathione peroxidase family
AL483_RS17920	COG1923	regulation of RNA biosynthetic process
AL483_RS17925	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
AL483_RS17935	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
AL483_RS17940	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AL483_RS17945	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
AL483_RS17955	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
AL483_RS17960	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
AL483_RS17965	COG0584	glycerophosphoryl diester phosphodiesterase
AL483_RS17975	COG4550	Control of competence regulator ComK, YlbF/YmcA
AL483_RS17980	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AL483_RS17990	COG0601	transmembrane transport
AL483_RS17995	COG4608	Belongs to the ABC transporter superfamily
AL483_RS18000	COG0444	Belongs to the ABC transporter superfamily
AL483_RS18005	COG0747	negative chemotaxis
AL483_RS18020	COG1013	pyruvate-flavodoxin oxidoreductase activity
AL483_RS18025	COG0674	pyruvate-flavodoxin oxidoreductase activity
AL483_RS18025	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
AL483_RS18030	COG1692	metallophosphoesterase
AL483_RS18040	COG0583	DNA-binding transcription factor activity
AL483_RS18050	COG1418	mRNA catabolic process
AL483_RS18055	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
AL483_RS18060	COG1058	Belongs to the CinA family
AL483_RS18060	COG1546	Belongs to the CinA family
AL483_RS18080	COG0300	oxidoreductase activity
AL483_RS18085	COG0612	Peptidase, M16
AL483_RS18090	COG0612	Peptidase, M16
AL483_RS18095	COG2188	Transcriptional regulator
AL483_RS18105	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
AL483_RS18115	COG1185	polyribonucleotide nucleotidyltransferase activity
AL483_RS18120	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
AL483_RS18125	COG0196	riboflavin kinase activity
AL483_RS18130	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AL483_RS18140	COG3850	Histidine kinase
AL483_RS18140	COG5002	protein histidine kinase activity
AL483_RS18145	COG0745	RESPONSE REGULATOR receiver
AL483_RS18155	COG1929	Belongs to the glycerate kinase type-1 family
AL483_RS18160	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
AL483_RS18170	COG0584	glycerophosphoryl diester phosphodiesterase
AL483_RS18180	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
AL483_RS18185	COG1358	cellular component organization or biogenesis
AL483_RS18190	COG2740	Nucleic-acid-binding protein implicated in transcription termination
AL483_RS18195	COG0195	Participates in both transcription termination and antitermination
AL483_RS18200	COG0779	Required for maturation of 30S ribosomal subunits
AL483_RS18210	COG0442	prolyl-tRNA aminoacylation
AL483_RS18220	COG4589	Belongs to the CDS family
AL483_RS18230	COG0233	cytoplasmic translational termination
AL483_RS18235	COG0528	UMP kinase activity
AL483_RS18245	COG0052	Belongs to the universal ribosomal protein uS2 family
AL483_RS18250	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
AL483_RS18255	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
AL483_RS18260	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
AL483_RS18265	COG4974	Belongs to the 'phage' integrase family
AL483_RS18270	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
AL483_RS18275	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AL483_RS18280	COG0758	DNA mediated transformation
AL483_RS18285	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
AL483_RS18290	COG0045	succinate-CoA ligase (ADP-forming) activity
AL483_RS18295	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AL483_RS18315	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AL483_RS18320	COG4485	Bacterial membrane protein, YfhO
AL483_RS18340	COG0335	large ribosomal subunit rRNA binding
AL483_RS18345	COG0336	Belongs to the RNA methyltransferase TrmD family
AL483_RS18350	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
AL483_RS18355	COG0228	four-way junction DNA binding
AL483_RS18360	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AL483_RS18365	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
AL483_RS18370	COG0552	protein localization to endoplasmic reticulum
AL483_RS18375	COG1196	nuclear chromosome segregation
AL483_RS18380	COG0571	ribonuclease III activity
AL483_RS18385	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AL483_RS18400	COG0416	fatty acid biosynthetic process
AL483_RS18405	COG1349	DNA-binding transcription factor activity
AL483_RS18415	COG1760	l-serine dehydratase
AL483_RS18420	COG1760	l-serine dehydratase
AL483_RS18425	COG1461	Dihydroxyacetone kinase
AL483_RS18430	COG1302	Protein conserved in bacteria
AL483_RS18440	COG1564	THIamine pyrophosphokinase
AL483_RS18445	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AL483_RS18450	COG1162	GTPase activity
AL483_RS18460	COG0631	protein serine/threonine phosphatase activity
AL483_RS18465	COG0820	rRNA (adenine-C2-)-methyltransferase activity
AL483_RS18470	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AL483_RS18470	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AL483_RS18475	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AL483_RS18520	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AL483_RS18525	COG0110	maltose O-acetyltransferase activity
AL483_RS18530	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AL483_RS18555	COG2910	NAD(P)H-binding
AL483_RS18560	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AL483_RS18565	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AL483_RS18575	COG1758	RNA polymerase activity
AL483_RS18580	COG0194	GDP metabolic process
AL483_RS18605	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
AL483_RS18610	COG0284	orotidine-5'-phosphate decarboxylase activity
AL483_RS18615	COG0167	dihydroorotate dehydrogenase activity
AL483_RS18620	COG0543	2 iron, 2 sulfur cluster binding
AL483_RS18625	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
AL483_RS18630	COG0505	Belongs to the CarA family
AL483_RS18640	COG0540	Belongs to the ATCase OTCase family
AL483_RS18650	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
AL483_RS18665	COG1518	maintenance of DNA repeat elements
AL483_RS18675	COG0564	pseudouridine synthase activity
AL483_RS18680	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
AL483_RS18690	COG2514	catechol 2,3-dioxygenase activity
AL483_RS18700	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
AL483_RS18705	COG3599	regulation of cell shape
AL483_RS18715	COG0762	integral membrane protein
AL483_RS18720	COG1799	cell septum assembly
AL483_RS18725	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
AL483_RS18740	COG0849	cell division
AL483_RS18750	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
AL483_RS18755	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AL483_RS18760	COG0768	penicillin binding
AL483_RS18765	COG4839	cell division protein FtsL
AL483_RS18770	COG0275	rRNA processing
AL483_RS18775	COG2001	Belongs to the MraZ family
AL483_RS18780	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
AL483_RS18785	COG0454	-acetyltransferase
AL483_RS18790	COG1011	Hydrolase
AL483_RS18825	COG2176	DNA-directed DNA polymerase activity
AL483_RS18840	COG0346	lactoylglutathione lyase activity
AL483_RS18855	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
AL483_RS18865	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AL483_RS18870	COG1053	succinate dehydrogenase
AL483_RS18875	COG2009	succinate dehydrogenase
AL483_RS18880	COG0322	excinuclease ABC activity
AL483_RS18885	COG3118	belongs to the thioredoxin family
AL483_RS18890	COG1193	negative regulation of DNA recombination
AL483_RS18895	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
AL483_RS18895	COG1796	DNA polymerase
AL483_RS18910	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AL483_RS18915	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AL483_RS18915	COG0072	phenylalanine-tRNA ligase activity
AL483_RS18920	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
AL483_RS18925	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AL483_RS18930	COG0333	Belongs to the bacterial ribosomal protein bL32 family
AL483_RS18945	COG1323	Belongs to the UPF0348 family
AL483_RS18955	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
AL483_RS18960	COG0742	ribosomal rna small subunit methyltransferase
AL483_RS18975	COG0584	glycerophosphoryl diester phosphodiesterase
AL483_RS18980	COG3679	Belongs to the UPF0342 family
AL483_RS18995	COG0109	protoheme IX farnesyltransferase activity
AL483_RS19000	COG1612	heme a metabolic process
AL483_RS19010	COG0772	Belongs to the SEDS family
AL483_RS19015	COG4838	Belongs to the UPF0358 family
AL483_RS19020	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
AL483_RS19030	COG1217	gtp-binding protein TYPA
AL483_RS19040	COG0483	inositol monophosphate 1-phosphatase activity
AL483_RS19045	COG4493	Belongs to the UPF0637 family
AL483_RS19050	COG1914	H( )-stimulated, divalent metal cation uptake system
AL483_RS19070	COG1177	transmembrane transport
AL483_RS19075	COG1176	ABC-type spermidine putrescine transport system, permease component I
AL483_RS19090	COG4476	Belongs to the UPF0223 family
AL483_RS19120	COG0242	peptide deformylase activity
AL483_RS19130	COG5503	Protein of unknown function (DUF1447)
AL483_RS19140	COG0569	domain protein
AL483_RS19145	COG1294	oxidase, subunit
AL483_RS19150	COG1271	oxidase subunit
AL483_RS19160	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AL483_RS19175	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
AL483_RS19190	COG1122	ATPase activity
AL483_RS19195	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
AL483_RS19205	COG0151	Belongs to the GarS family
AL483_RS19210	COG0138	bifunctional purine biosynthesis protein purh
AL483_RS19220	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
AL483_RS19225	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
AL483_RS19230	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AL483_RS19235	COG0047	phosphoribosylformylglycinamidine synthase activity
AL483_RS19240	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AL483_RS19245	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
AL483_RS19250	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
AL483_RS19255	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
AL483_RS19260	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
AL483_RS19265	COG1363	Peptidase, m42
AL483_RS19270	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AL483_RS19270	COG1017	nitric oxide dioxygenase activity
AL483_RS19280	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AL483_RS19290	COG1845	cytochrome c oxidase, subunit III
AL483_RS19295	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
AL483_RS19305	COG1349	DNA-binding transcription factor activity
AL483_RS19315	COG0698	ribose 5-phosphate isomerase
AL483_RS19320	COG1105	Belongs to the carbohydrate kinase PfkB family
AL483_RS19340	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AL483_RS19345	COG2723	6-phospho-beta-galactosidase activity
AL483_RS19350	COG1447	Phosphotransferase system cellobiose-specific component IIA
AL483_RS19370	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AL483_RS19375	COG1959	2 iron, 2 sulfur cluster binding
AL483_RS19385	COG1316	TRANSCRIPTIONal
AL483_RS19410	COG3594	Acyltransferase
AL483_RS19415	COG0436	Aminotransferase
AL483_RS19425	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
AL483_RS19430	COG0596	Alpha beta hydrolase
AL483_RS19435	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
AL483_RS19440	COG1169	isochorismate synthase
AL483_RS19445	COG1575	Belongs to the MenA family. Type 1 subfamily
AL483_RS19455	COG2314	TM2 domain
AL483_RS19470	COG4873	Protein conserved in bacteria
AL483_RS19535	COG1129	ABC transporter
AL483_RS19560	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
AL483_RS19565	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AL483_RS19570	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AL483_RS19580	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
AL483_RS19585	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
AL483_RS19590	COG0107	imidazoleglycerol-phosphate synthase activity
AL483_RS19595	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
AL483_RS19595	COG0140	phosphoribosyl-ATP diphosphatase activity
AL483_RS19600	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AL483_RS19605	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AL483_RS19610	COG0861	Integral membrane protein TerC family
AL483_RS19615	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
AL483_RS19630	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AL483_RS19635	COG2814	Major facilitator Superfamily
AL483_RS19640	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
AL483_RS19645	COG2382	esterase
AL483_RS19655	COG0628	permease
AL483_RS19660	COG2814	Major facilitator Superfamily
AL483_RS19670	COG0569	domain protein
AL483_RS19670	COG0475	glutathione-regulated potassium exporter activity
AL483_RS19675	COG2239	Acts as a magnesium transporter
AL483_RS19680	COG0564	pseudouridine synthase activity
AL483_RS19685	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AL483_RS19690	COG2357	RelA SpoT domain protein
AL483_RS19705	COG2346	COG2346, Truncated hemoglobins
AL483_RS19725	COG1164	Oligoendopeptidase f
AL483_RS19730	COG4862	establishment of competence for transformation
AL483_RS19735	COG1393	Belongs to the ArsC family
AL483_RS19740	COG0180	Tryptophanyl-tRNA synthetase
AL483_RS19750	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
AL483_RS19755	COG0454	-acetyltransferase
AL483_RS19760	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AL483_RS19765	COG4166	transmembrane transport
AL483_RS19770	COG4608	Belongs to the ABC transporter superfamily
AL483_RS19775	COG0444	Belongs to the ABC transporter superfamily
AL483_RS19780	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AL483_RS19785	COG0601	transmembrane transport
AL483_RS19800	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AL483_RS19825	COG0561	phosphatase activity
AL483_RS19845	COG1074	ATP-dependent DNA helicase activity
AL483_RS19850	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
AL483_RS19865	COG0398	Pfam SNARE associated Golgi protein
AL483_RS19870	COG0166	Belongs to the GPI family
AL483_RS19875	COG0137	argininosuccinate synthase activity
AL483_RS19880	COG0165	Argininosuccinate lyase
AL483_RS19890	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AL483_RS19895	COG1012	belongs to the aldehyde dehydrogenase family
AL483_RS19900	COG1902	pentaerythritol trinitrate reductase activity
AL483_RS19905	COG1098	S1 RNA binding domain
AL483_RS19925	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AL483_RS19935	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AL483_RS19935	COG2111	Na H antiporter
AL483_RS19940	COG2111	Na H antiporter
AL483_RS19945	COG1006	Multisubunit Na H antiporter MnhC subunit
AL483_RS19950	COG0651	ATP synthesis coupled electron transport
AL483_RS19955	COG1863	multisubunit Na H antiporter MnhE subunit
AL483_RS19960	COG2212	antiporter activity
AL483_RS19975	COG2050	protein possibly involved in aromatic compounds catabolism
AL483_RS19980	COG2056	Na+-H+ antiporter family
AL483_RS19985	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AL483_RS19990	COG1252	NADH dehydrogenase
AL483_RS19995	COG0316	Belongs to the HesB IscA family
AL483_RS20000	COG4844	belongs to the
AL483_RS20005	COG1252	NADH dehydrogenase
AL483_RS20010	COG4837	Protein of unknown function (DUF1462)
AL483_RS20015	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
AL483_RS20020	COG0789	Transcriptional regulator
AL483_RS20025	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
AL483_RS20030	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AL483_RS20035	COG1696	Membrane protein involved in D-alanine export
AL483_RS20040	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AL483_RS20050	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AL483_RS20055	COG0647	UMP catabolic process
AL483_RS20060	COG2445	Protein of unknown function DUF86
AL483_RS20070	COG4470	Protein conserved in bacteria
AL483_RS20075	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AL483_RS20080	COG0737	Belongs to the 5'-nucleotidase family
AL483_RS20085	COG0730	response to heat
AL483_RS20090	COG1801	Protein of unknown function DUF72
AL483_RS20100	COG1253	flavin adenine dinucleotide binding
AL483_RS20120	COG0822	iron-sulfur transferase activity
AL483_RS20130	COG0719	Fe-S assembly protein
AL483_RS20135	COG0396	ATPase activity
AL483_RS20215	COG0582	viral genome integration into host DNA
AL483_RS20220	COG1464	Belongs to the NlpA lipoprotein family
AL483_RS20225	COG2011	ABC-type metal ion transport system permease component
AL483_RS20230	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AL483_RS20235	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AL483_RS20240	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
AL483_RS20245	COG0509	glycine decarboxylation via glycine cleavage system
AL483_RS20250	COG1393	Belongs to the ArsC family
AL483_RS20255	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AL483_RS20265	COG0710	3-dehydroquinate dehydratase activity
AL483_RS20290	COG1704	LemA family
AL483_RS20295	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AL483_RS20305	COG1278	Cold shock
AL483_RS20310	COG0300	oxidoreductase activity
AL483_RS20315	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AL483_RS20330	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
AL483_RS20335	COG0557	exoribonuclease II activity
AL483_RS20340	COG1647	Serine aminopeptidase, S33
AL483_RS20345	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AL483_RS20355	COG0148	phosphopyruvate hydratase activity
AL483_RS20360	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
AL483_RS20370	COG0126	phosphoglycerate kinase activity
AL483_RS20400	COG0740	serine-type endopeptidase activity
AL483_RS20510	COG1114	Component of the transport system for branched-chain amino acids
AL483_RS20515	COG2814	Major facilitator Superfamily
AL483_RS20520	COG1481	regulation of sporulation
AL483_RS20525	COG0391	Required for morphogenesis under gluconeogenic growth conditions
AL483_RS20530	COG1660	Displays ATPase and GTPase activities
AL483_RS20545	COG0110	maltose O-acetyltransferase activity
AL483_RS20550	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
AL483_RS20555	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
AL483_RS20560	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AL483_RS20580	COG3942	CHAP domain
AL483_RS20590	COG0653	protein targeting
AL483_RS20595	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
AL483_RS20600	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
AL483_RS20605	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
AL483_RS20615	COG1739	Uncharacterized protein family UPF0029
AL483_RS20620	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AL483_RS20625	COG2199	diguanylate cyclase activity
AL483_RS20645	COG2195	Cleaves the N-terminal amino acid of tripeptides
AL483_RS20650	COG1929	Belongs to the glycerate kinase type-1 family
AL483_RS20670	COG0812	UDP-N-acetylmuramate dehydrogenase activity
AL483_RS20680	COG4607	ABC-type enterochelin transport system periplasmic component
AL483_RS20685	COG4604	ABC transporter, ATP-binding protein
AL483_RS20690	COG4605	iron ion homeostasis
AL483_RS20695	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AL483_RS20700	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AL483_RS20705	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AL483_RS20710	COG1780	Probably involved in ribonucleotide reductase function
AL483_RS20720	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
AL483_RS20725	COG3104	oligopeptide transport
AL483_RS20730	COG3104	oligopeptide transport
AL483_RS20740	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AL483_RS20745	COG1174	glycine betaine transport
AL483_RS20755	COG0514	ATP-dependent DNA helicase (RecQ)
AL483_RS20760	COG0488	(ABC) transporter
AL483_RS20765	COG1368	sulfuric ester hydrolase activity
AL483_RS20775	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
AL483_RS20800	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
AL483_RS20805	COG0720	synthase
AL483_RS20825	COG0656	L-ascorbic acid biosynthetic process
AL483_RS20835	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
AL483_RS20860	COG1253	flavin adenine dinucleotide binding
AL483_RS20865	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AL483_RS20865	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AL483_RS20865	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AL483_RS20870	COG1105	Belongs to the carbohydrate kinase PfkB family
AL483_RS20875	COG1349	DNA-binding transcription factor activity
AL483_RS20880	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AL483_RS20890	COG0039	L-malate dehydrogenase activity
AL483_RS20895	COG1464	Belongs to the NlpA lipoprotein family
AL483_RS20915	COG0471	metal ion transport
AL483_RS20920	COG0039	L-malate dehydrogenase activity
AL483_RS20930	COG4989	oxidoreductase activity
AL483_RS20935	COG0523	cobalamin synthesis protein
AL483_RS20945	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
AL483_RS20950	COG4988	ABC transporter
AL483_RS20955	COG1968	undecaprenyl-diphosphatase activity
AL483_RS20965	COG1671	Belongs to the UPF0178 family
AL483_RS21005	COG0583	DNA-binding transcription factor activity
AL483_RS21055	COG0217	transcriptional regulatory protein
AL483_RS21065	COG2207	Transcriptional regulator
AL483_RS21075	COG1388	LysM domain
AL483_RS21075	COG3942	CHAP domain
AL483_RS21080	COG0306	phosphate transporter
AL483_RS21085	COG1392	Phosphate transport regulator
AL483_RS21090	COG0577	efflux transmembrane transporter activity
AL483_RS21095	COG1136	(ABC) transporter
AL483_RS21100	COG2205	protein histidine kinase activity
AL483_RS21120	COG3949	Membrane
AL483_RS21130	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AL483_RS21135	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AL483_RS21140	COG1120	ATPase activity
AL483_RS21145	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AL483_RS21150	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AL483_RS21155	COG1132	(ABC) transporter
AL483_RS21160	COG1686	Belongs to the peptidase S11 family
AL483_RS21165	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
AL483_RS21170	COG1216	Glycosyl transferase, family 2
AL483_RS21175	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
AL483_RS21180	COG1682	transport, permease protein
AL483_RS21185	COG1134	teichoic acid transport
AL483_RS21190	COG5609	conserved protein (DUF2294)
AL483_RS21195	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AL483_RS21210	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
AL483_RS21225	COG1247	-acetyltransferase
AL483_RS21230	COG0671	phosphoesterase, PA-phosphatase related
AL483_RS21240	COG1121	(ABC) transporter
AL483_RS21245	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AL483_RS21250	COG0803	Belongs to the bacterial solute-binding protein 9 family
AL483_RS21255	COG2348	transferase activity, transferring amino-acyl groups
AL483_RS21260	COG0025	NhaP-type Na H and K H
AL483_RS21305	COG0546	phosphoglycolate phosphatase activity
AL483_RS21310	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AL483_RS21315	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AL483_RS21320	COG0018	arginyl-trna synthetase
AL483_RS21330	COG1473	amidohydrolase
AL483_RS21340	COG1078	dGTPase activity
AL483_RS21345	COG0519	Catalyzes the synthesis of GMP from XMP
AL483_RS21355	COG4844	belongs to the
AL483_RS21375	COG0095	Lipoate-protein ligase
AL483_RS21380	COG0280	phosphate acetyltransferase
AL483_RS21385	COG3253	May function as heme-dependent peroxidase
AL483_RS21405	COG0586	Pfam SNARE associated Golgi protein
AL483_RS21410	COG0531	amino acid
AL483_RS21415	COG2363	Small membrane protein
AL483_RS21425	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
AL483_RS21435	COG0737	Belongs to the 5'-nucleotidase family
AL483_RS21450	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
AL483_RS21455	COG3639	organic phosphonate transmembrane transporter activity
AL483_RS21465	COG1469	GTP cyclohydrolase I activity
AL483_RS21470	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
AL483_RS21475	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
AL483_RS21480	COG0363	glucosamine-6-phosphate deaminase activity
AL483_RS21485	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
AL483_RS21495	COG0431	NADPH-dependent FMN reductase
AL483_RS21500	COG0561	phosphatase activity
AL483_RS21510	COG1428	Deoxynucleoside kinase
AL483_RS21520	COG0561	phosphatase activity
AL483_RS21530	COG0546	phosphoglycolate phosphatase activity
AL483_RS21535	COG2832	Protein of unknown function (DUF454)
AL483_RS21545	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AL483_RS21560	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
AL483_RS21565	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
AL483_RS21585	COG1473	amidohydrolase
AL483_RS21590	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AL483_RS21595	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AL483_RS21600	COG0049	tRNA binding
AL483_RS21605	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
AL483_RS21615	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AL483_RS21620	COG0085	RNA polymerase activity
AL483_RS21625	COG2813	Specifically methylates the guanine in position
AL483_RS21630	COG0222	ribosome binding
AL483_RS21635	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
AL483_RS21645	COG0081	regulation of translation
AL483_RS21650	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
AL483_RS21655	COG0250	Participates in transcription elongation, termination and antitermination
AL483_RS21665	COG0267	Belongs to the bacterial ribosomal protein bL33 family
AL483_RS21680	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AL483_RS21685	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
AL483_RS21690	COG0215	cysteine-tRNA ligase activity
AL483_RS21695	COG1045	serine acetyltransferase
AL483_RS21705	COG4956	integral membrane protein (PIN domain superfamily)
AL483_RS21710	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
AL483_RS21715	COG0542	response to heat
AL483_RS21720	COG3869	Catalyzes the specific phosphorylation of arginine residues in
AL483_RS21725	COG3880	PFAM UvrB UvrC protein
AL483_RS21735	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AL483_RS21750	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
AL483_RS21755	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
AL483_RS21760	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AL483_RS21770	COG2814	Major facilitator Superfamily
AL483_RS21855	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
AL483_RS21860	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AL483_RS21865	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AL483_RS21885	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
AL483_RS21890	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AL483_RS21905	COG1098	S1 RNA binding domain
AL483_RS21915	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
AL483_RS21920	COG3956	TIGRFAM MazG family protein
AL483_RS21925	COG2244	polysaccharide biosynthetic process
AL483_RS21930	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AL483_RS21935	COG0193	aminoacyl-tRNA hydrolase activity
AL483_RS21940	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
AL483_RS21945	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AL483_RS21950	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
AL483_RS21955	COG2088	sporulation resulting in formation of a cellular spore
AL483_RS21960	COG0251	oxidation-reduction process
AL483_RS21965	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AL483_RS21975	COG4466	Protein conserved in bacteria
AL483_RS21980	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AL483_RS21985	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
AL483_RS21990	COG0084	hydrolase, TatD family'
AL483_RS21995	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AL483_RS21995	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AL483_RS22035	COG3942	CHAP domain
AL483_RS22035	COG1388	LysM domain
AL483_RS22070	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
AL483_RS22075	COG2827	Endonuclease containing a URI domain
AL483_RS22080	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
AL483_RS22090	COG1774	PSP1 C-terminal conserved region
AL483_RS22095	COG0470	DNA polymerase III
AL483_RS22100	COG3870	Protein conserved in bacteria
AL483_RS22105	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AL483_RS22110	COG1982	Orn Lys Arg decarboxylase major
AL483_RS22130	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
AL483_RS22140	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AL483_RS22155	COG2814	Major facilitator Superfamily
AL483_RS22160	COG0583	DNA-binding transcription factor activity
AL483_RS22170	COG2188	Transcriptional regulator
AL483_RS22175	COG0366	Alpha amylase catalytic
AL483_RS22180	COG1263	PTS System
AL483_RS22180	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AL483_RS22185	COG0346	lactoylglutathione lyase activity
AL483_RS22195	COG0493	'glutamate synthase
AL483_RS22200	COG0067	glutamate synthase
AL483_RS22200	COG0069	glutamate synthase activity
AL483_RS22200	COG0070	glutamate synthase
AL483_RS22205	COG0583	DNA-binding transcription factor activity
AL483_RS22230	COG4841	protein insertion into membrane
AL483_RS22240	COG0737	Belongs to the 5'-nucleotidase family
AL483_RS22245	COG2162	N-hydroxyarylamine O-acetyltransferase activity
AL483_RS22255	COG0626	cystathionine gamma-synthase activity
AL483_RS22260	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AL483_RS22265	COG1266	CAAX protease self-immunity
AL483_RS22270	COG0733	neurotransmitter:sodium symporter activity
AL483_RS22280	COG1647	Serine aminopeptidase, S33
AL483_RS22285	COG1755	Isoprenylcysteine carboxyl methyltransferase
AL483_RS22290	COG1279	arginine transmembrane transporter activity
AL483_RS22300	COG0346	lactoylglutathione lyase activity
AL483_RS22320	COG1695	Transcriptional regulator
AL483_RS22325	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
AL483_RS22330	COG1683	Conserved Protein
AL483_RS22355	COG0529	Catalyzes the synthesis of activated sulfate
AL483_RS22360	COG2046	Belongs to the sulfate adenylyltransferase family
AL483_RS22365	COG0730	response to heat
AL483_RS22375	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AL483_RS22380	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
AL483_RS22385	COG0175	sulfate reduction
AL483_RS22390	COG1216	Glycosyl transferase, family 2
AL483_RS22400	COG1051	belongs to the nudix hydrolase family
AL483_RS22415	COG2514	catechol 2,3-dioxygenase activity
AL483_RS22420	COG0519	Catalyzes the synthesis of GMP from XMP
AL483_RS22420	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AL483_RS22430	COG2233	PERMEase
AL483_RS22435	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AL483_RS22455	COG1823	symporter activity
AL483_RS22460	COG0778	Nitroreductase
AL483_RS22470	COG0450	alkyl hydroperoxide reductase
AL483_RS22475	COG3634	alkyl hydroperoxide reductase activity
AL483_RS22495	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AL483_RS22500	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AL483_RS22515	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
AL483_RS22525	COG0360	Binds together with S18 to 16S ribosomal RNA
AL483_RS22545	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AL483_RS22565	COG0012	GTP binding
AL483_RS22570	COG4481	Protein conserved in bacteria
AL483_RS22575	COG0668	transmembrane transport
AL483_RS22580	COG1475	DNA binding
AL483_RS22585	COG0626	cystathionine gamma-synthase activity
AL483_RS22590	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
AL483_RS22590	COG0646	methionine synthase
AL483_RS22595	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
AL483_RS22605	COG0436	Aminotransferase
AL483_RS22615	COG1475	DNA binding
AL483_RS22620	COG0357	Ribosomal RNA small subunit methyltransferase G
AL483_RS22630	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
AL483_RS22635	COG0594	ribonuclease P activity
AL483_RS22645	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
AL483_RS22650	COG0592	DNA-directed DNA polymerase activity
AL483_RS22660	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AL483_RS22665	COG0187	DNA topoisomerase II activity
AL483_RS22675	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AL483_RS22680	COG2986	histidine ammonia-lyase
AL483_RS22685	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
AL483_RS22705	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
AL483_RS22710	COG0359	binds to the 23S rRNA
AL483_RS22715	COG0305	Participates in initiation and elongation during chromosome replication
AL483_RS22725	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AL483_RS22740	COG0745	RESPONSE REGULATOR receiver
AL483_RS22745	COG5002	protein histidine kinase activity
AL483_RS22750	COG4863	YycH protein
AL483_RS22760	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
AL483_RS22770	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
AL483_RS22775	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
AL483_RS22810	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AL483_RS22815	COG1113	amino acid transport
AL483_RS22925	COG0640	Transcriptional regulator
AL483_RS22935	COG2217	Heavy metal translocating P-type atpase
AL483_RS22950	COG0789	Transcriptional regulator
AL483_RS22960	COG0702	epimerase
AL483_RS22965	COG2130	NADP-dependent
AL483_RS22980	COG0640	Transcriptional regulator
AL483_RS22985	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AL483_RS23000	COG2217	Heavy metal translocating P-type atpase
AL483_RS23005	COG1388	LysM domain
AL483_RS23015	COG0515	serine threonine protein kinase
AL483_RS23075	COG0745	RESPONSE REGULATOR receiver
AL483_RS23080	COG5002	protein histidine kinase activity
AL483_RS23100	COG1280	lysine exporter protein (LysE YggA)
AL483_RS23145	COG1705	Flagellar rod assembly protein muramidase FlgJ
AL483_RS23145	COG3942	CHAP domain
AL483_RS23160	COG1064	alcohol dehydrogenase
AL483_RS23170	COG3477	response to acidic pH
AL483_RS23175	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AL483_RS23175	COG3711	transcriptional antiterminator
AL483_RS23180	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AL483_RS23180	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AL483_RS23180	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AL483_RS23185	COG1482	cell wall glycoprotein biosynthetic process
AL483_RS23190	COG0402	S-adenosylhomocysteine deaminase activity
AL483_RS23195	COG1686	Belongs to the peptidase S11 family
AL483_RS23220	COG1609	Transcriptional regulator
AL483_RS23230	COG1869	D-ribose catabolic process
AL483_RS23260	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
AL483_RS23275	COG0363	glucosamine-6-phosphate deaminase activity
AL483_RS23280	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
AL483_RS23295	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AL483_RS23300	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AL483_RS23305	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AL483_RS23330	COG0778	Nitroreductase
AL483_RS23345	COG1063	alcohol dehydrogenase
AL483_RS23365	COG2851	Citrate transporter
AL483_RS23390	COG1250	3-hydroxyacyl-CoA dehydrogenase
AL483_RS23395	COG3246	L-lysine catabolic process to acetate
AL483_RS23405	COG0730	response to heat
AL483_RS23410	COG1937	Protein conserved in bacteria
AL483_RS23415	COG2210	Belongs to the sulfur carrier protein TusA family
AL483_RS23420	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AL483_RS23435	COG1012	belongs to the aldehyde dehydrogenase family
AL483_RS23440	COG0531	amino acid
AL483_RS23445	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AL483_RS23450	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AL483_RS23460	COG0753	catalase activity
AL483_RS23465	COG0662	Cupin 2, conserved barrel domain protein
AL483_RS23485	COG0431	NADPH-dependent FMN reductase
AL483_RS23485	COG1053	succinate dehydrogenase
AL483_RS23485	COG3976	FMN-binding domain protein
AL483_RS23525	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
AL483_RS23560	COG3711	transcriptional antiterminator
AL483_RS23565	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AL483_RS23590	COG3586	endonuclease activity
AL483_RS23595	COG2188	Transcriptional regulator
AL483_RS23600	COG2222	sugar isomerase
AL483_RS23610	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AL483_RS23610	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
AL483_RS23615	COG3715	PTS system
AL483_RS23620	COG3716	PTS system mannose fructose sorbose family IID component
AL483_RS23630	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
AL483_RS23650	COG1609	Transcriptional regulator
AL483_RS23660	COG1070	Carbohydrate kinase
AL483_RS23665	COG1063	alcohol dehydrogenase
AL483_RS23695	COG3181	Tripartite tricarboxylate transporter family receptor
AL483_RS23715	COG1966	Carbon starvation protein
AL483_RS23720	COG1054	Belongs to the UPF0176 family
AL483_RS23725	COG2388	GCN5-related N-acetyl-transferase
AL483_RS23740	COG2388	GCN5-related N-acetyl-transferase
AL483_RS23745	COG0346	lactoylglutathione lyase activity
AL483_RS23755	COG0789	Transcriptional regulator
AL483_RS23760	COG1664	Polymer-forming cytoskeletal
AL483_RS23770	COG0006	proline dipeptidase activity
AL483_RS23780	COG0477	Major facilitator Superfamily
AL483_RS23785	COG0667	Aldo Keto reductase
AL483_RS23835	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AL483_RS23840	COG1028	Short-chain dehydrogenase reductase Sdr
AL483_RS23850	COG1288	antiporter activity
AL483_RS23865	COG3871	stress protein (general stress protein 26)
AL483_RS23870	COG1929	Belongs to the glycerate kinase type-1 family
AL483_RS23880	COG1511	domain protein
AL483_RS23890	COG3321	synthase
AL483_RS23890	COG0604	alcohol dehydrogenase
AL483_RS23900	COG0579	oxidoreductase
AL483_RS23910	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AL483_RS23915	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AL483_RS23925	COG1757	Na H antiporter
AL483_RS23940	COG4195	phage-related replication protein
AL483_RS23965	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
AL483_RS23975	COG2207	Transcriptional regulator
AL483_RS23975	COG1609	Transcriptional regulator
AL483_RS23980	COG4932	domain protein
AL483_RS24005	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AL483_RS24015	COG0556	nucleotide-excision repair
AL483_RS24030	COG0508	dehydrogenase complex catalyzes the overall conversion of
AL483_RS24035	COG0022	dehydrogenase e1 component
AL483_RS24040	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AL483_RS24045	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AL483_RS24065	COG1288	antiporter activity
AL483_RS24070	COG0549	Belongs to the carbamate kinase family
AL483_RS24075	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AL483_RS24130	COG0706	membrane insertase activity
AL483_RS24145	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AL483_RS24150	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
AL483_RS24180	COG4221	oxidoreductase activity
AL483_RS24185	COG0069	glutamate synthase activity
AL483_RS24190	COG2814	Major facilitator Superfamily
AL483_RS24195	COG4336	lyase activity
AL483_RS24220	COG0531	amino acid
AL483_RS24230	COG0753	catalase activity
AL483_RS24235	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
AL483_RS24250	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AL483_RS24255	COG2011	ABC-type metal ion transport system permease component
AL483_RS24260	COG1464	Belongs to the NlpA lipoprotein family
AL483_RS24300	COG2210	Belongs to the sulfur carrier protein TusA family
AL483_RS24310	COG3961	Belongs to the TPP enzyme family
AL483_RS24315	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AL483_RS24320	COG1510	regulation of RNA biosynthetic process
AL483_RS24325	COG1012	belongs to the aldehyde dehydrogenase family
AL483_RS24330	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
AL483_RS24335	COG3583	domain protein
AL483_RS24335	COG3583	domain protein
AL483_RS24345	COG1181	Belongs to the D-alanine--D-alanine ligase family
AL483_RS24355	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AL483_RS24390	COG0438	transferase activity, transferring glycosyl groups
AL483_RS24395	COG0463	Glycosyl transferase, family 2
AL483_RS24395	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
AL483_RS24405	COG0494	nUDIX hydrolase
AL483_RS24425	COG3588	fructose-bisphosphate aldolase
AL483_RS24430	COG2258	MOSC domain
AL483_RS24460	COG1454	alcohol dehydrogenase
AL483_RS24460	COG1012	belongs to the aldehyde dehydrogenase family
AL483_RS24470	COG0640	Transcriptional regulator
AL483_RS24480	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
AL483_RS24490	COG1737	Transcriptional regulator
AL483_RS24505	COG0640	Transcriptional regulator
AL483_RS24520	COG1131	(ABC) transporter
AL483_RS24545	COG0582	viral genome integration into host DNA
AL483_RS24550	COG2111	Na H antiporter
AL483_RS24550	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AL483_RS24555	COG2111	Na H antiporter
AL483_RS24560	COG1006	Multisubunit Na H antiporter MnhC subunit
AL483_RS24570	COG1863	multisubunit Na H antiporter MnhE subunit
AL483_RS24575	COG2212	antiporter activity
AL483_RS24580	COG1320	monovalent cation:proton antiporter activity
AL483_RS24590	COG1113	amino acid transport
AL483_RS24600	COG1131	(ABC) transporter
AL483_RS24610	COG2824	Alkylphosphonate utilization operon protein PhnA
AL483_RS24620	COG2376	Dihydroxyacetone kinase
AL483_RS24625	COG1461	Dihydroxyacetone kinase
AL483_RS24630	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
AL483_RS24635	COG1216	Glycosyl transferase, family 2
AL483_RS24635	COG1442	glycosyl transferase family 8
AL483_RS24655	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
AL483_RS24670	COG0531	amino acid
AL483_RS24685	COG0463	Glycosyl transferase, family 2
AL483_RS24705	COG0446	pyridine nucleotide-disulphide oxidoreductase
AL483_RS24710	COG1131	(ABC) transporter
AL483_RS24730	COG1028	Short-chain dehydrogenase reductase Sdr
AL483_RS24750	COG0318	PFAM AMP-dependent synthetase and ligase
AL483_RS24755	COG0183	Belongs to the thiolase family
AL483_RS24765	COG2235	arginine
AL483_RS24775	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AL483_RS24780	COG1438	arginine binding
AL483_RS24785	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AL483_RS24790	COG2022	thiamine diphosphate biosynthetic process
AL483_RS24800	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AL483_RS24805	COG0352	thiamine-phosphate diphosphorylase activity
AL483_RS24825	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
AL483_RS24840	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AL483_RS24850	COG1131	(ABC) transporter
AL483_RS24865	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AL483_RS24870	COG2508	Transcriptional regulator
AL483_RS24875	COG1953	Uracil, thiamine, allantoin
AL483_RS24880	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
AL483_RS24895	COG3257	ureidoglycine aminohydrolase activity
AL483_RS24900	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
AL483_RS24905	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
AL483_RS24915	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
AL483_RS24930	COG2807	transmembrane transport
AL483_RS24935	COG5646	InterPro IPR014922
AL483_RS24940	COG2207	Transcriptional regulator
AL483_RS24955	COG2211	Major facilitator Superfamily
AL483_RS24960	COG1904	glucuronate isomerase
AL483_RS24965	COG1312	Catalyzes the dehydration of D-mannonate
AL483_RS24970	COG1028	Short-chain dehydrogenase reductase Sdr
AL483_RS24975	COG3250	beta-galactosidase activity
AL483_RS25000	COG1518	maintenance of DNA repeat elements
AL483_RS25025	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
AL483_RS25030	COG1984	allophanate hydrolase subunit 2
AL483_RS25035	COG0511	ligase activity, forming carbon-carbon bonds
AL483_RS25040	COG0439	Biotin carboxylase
AL483_RS25045	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
AL483_RS25050	COG1914	H( )-stimulated, divalent metal cation uptake system
AL483_RS25055	COG1070	Carbohydrate kinase
AL483_RS25070	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AL483_RS25120	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AL483_RS25135	COG3189	MarR family transcriptional regulator
AL483_RS25140	COG1882	Formate acetyltransferase
AL483_RS25155	COG3321	synthase
AL483_RS25155	COG0604	alcohol dehydrogenase
AL483_RS25165	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
AL483_RS25175	COG3001	Fructosamine kinase
AL483_RS25190	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
AL483_RS25205	COG3764	Sortase (surface protein transpeptidase)
AL483_RS25210	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
AL483_RS25215	COG4932	domain protein
AL483_RS25215	COG3266	domain, Protein
AL483_RS25215	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
AL483_RS25220	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AL483_RS25240	COG1136	(ABC) transporter
AL483_RS25245	COG0577	efflux transmembrane transporter activity
AL483_RS25250	COG0583	DNA-binding transcription factor activity
AL483_RS25255	COG1388	LysM domain
AL483_RS25260	COG1380	Effector of murein hydrolase LrgA
AL483_RS25270	COG0028	Belongs to the TPP enzyme family
AL483_RS25285	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
AL483_RS25290	COG1687	branched-chain amino acid
AL483_RS25295	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
AL483_RS25305	COG1609	Transcriptional regulator
AL483_RS25320	COG1760	l-serine dehydratase
AL483_RS25325	COG1760	l-serine dehydratase
AL483_RS25330	COG2249	NAD(P)H dehydrogenase (quinone) activity
AL483_RS25335	COG0778	Nitroreductase
AL483_RS25340	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AL483_RS25345	COG1132	(ABC) transporter
AL483_RS25350	COG1132	(ABC) transporter