CO689_RS08065 8a32a06c37c88e556e7db683b2f6aea3 156 Pfam PF00177 Ribosomal protein S7p/S5e 1 149 1.1E-66 T 28-03-2018 IPR023798 Ribosomal protein S7 domain CO689_RS08065 8a32a06c37c88e556e7db683b2f6aea3 156 PIRSF PIRSF002122 3 156 7.2E-58 T 28-03-2018 IPR000235 Ribosomal protein S5/S7 GO:0006412 CO689_RS08065 8a32a06c37c88e556e7db683b2f6aea3 156 SUPERFAMILY SSF47973 4 149 3.14E-60 T 28-03-2018 IPR023798 Ribosomal protein S7 domain CO689_RS08065 8a32a06c37c88e556e7db683b2f6aea3 156 Gene3D G3DSA:1.10.455.10 6 156 4.3E-59 T 28-03-2018 IPR023798 Ribosomal protein S7 domain CO689_RS08065 8a32a06c37c88e556e7db683b2f6aea3 156 TIGRFAM TIGR01029 rpsG_bact: ribosomal protein uS7 3 156 1.5E-68 T 28-03-2018 IPR005717 Ribosomal protein S7, bacterial/organellar-type GO:0003735|GO:0006412|GO:0015935 CO689_RS08065 8a32a06c37c88e556e7db683b2f6aea3 156 Hamap MF_00480_B 30S ribosomal protein S7 [rpsG]. 1 156 35.843 T 28-03-2018 IPR005717 Ribosomal protein S7, bacterial/organellar-type GO:0003735|GO:0006412|GO:0015935 CO689_RS08065 8a32a06c37c88e556e7db683b2f6aea3 156 ProSitePatterns PS00052 Ribosomal protein S7 signature. 20 46 - T 28-03-2018 IPR020606 Ribosomal protein S7, conserved site GO:0003723|GO:0003735|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CO689_RS03710 7908ddc5a44c5f2b45dd9fddf058c413 204 Gene3D G3DSA:3.10.300.10 1 196 2.4E-59 T 28-03-2018 IPR003180 Methylpurine-DNA glycosylase (MPG) GO:0003677|GO:0003905|GO:0006284 Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 CO689_RS03710 7908ddc5a44c5f2b45dd9fddf058c413 204 Pfam PF02245 Methylpurine-DNA glycosylase (MPG) 3 185 6.4E-51 T 28-03-2018 IPR003180 Methylpurine-DNA glycosylase (MPG) GO:0003677|GO:0003905|GO:0006284 Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 CO689_RS03710 7908ddc5a44c5f2b45dd9fddf058c413 204 SUPERFAMILY SSF50486 2 194 3.14E-56 T 28-03-2018 IPR011034 Formyl transferase, C-terminal-like GO:0003824 CO689_RS03710 7908ddc5a44c5f2b45dd9fddf058c413 204 TIGRFAM TIGR00567 3mg: DNA-3-methyladenine glycosylase 3 188 3.1E-47 T 28-03-2018 IPR003180 Methylpurine-DNA glycosylase (MPG) GO:0003677|GO:0003905|GO:0006284 Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 CO689_RS03710 7908ddc5a44c5f2b45dd9fddf058c413 204 Hamap MF_00527 Putative 3-methyladenine DNA glycosylase. 1 188 30.415 T 28-03-2018 IPR003180 Methylpurine-DNA glycosylase (MPG) GO:0003677|GO:0003905|GO:0006284 Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 CO689_RS02790 60e5c5a51af37ec0585d9b1bdef226ca 485 PRINTS PR01036 Tetracycline resistance protein TetB signature 401 420 3.0E-13 T 28-03-2018 CO689_RS02790 60e5c5a51af37ec0585d9b1bdef226ca 485 PRINTS PR01036 Tetracycline resistance protein TetB signature 109 129 3.0E-13 T 28-03-2018 CO689_RS02790 60e5c5a51af37ec0585d9b1bdef226ca 485 PRINTS PR01036 Tetracycline resistance protein TetB signature 303 327 3.0E-13 T 28-03-2018 CO689_RS02790 60e5c5a51af37ec0585d9b1bdef226ca 485 PRINTS PR01036 Tetracycline resistance protein TetB signature 18 42 3.0E-13 T 28-03-2018 CO689_RS02790 60e5c5a51af37ec0585d9b1bdef226ca 485 PRINTS PR01036 Tetracycline resistance protein TetB signature 139 163 3.0E-13 T 28-03-2018 CO689_RS02790 60e5c5a51af37ec0585d9b1bdef226ca 485 SUPERFAMILY SSF103473 249 479 5.49E-67 T 28-03-2018 IPR020846 Major facilitator superfamily domain CO689_RS02790 60e5c5a51af37ec0585d9b1bdef226ca 485 SUPERFAMILY SSF103473 7 197 5.49E-67 T 28-03-2018 IPR020846 Major facilitator superfamily domain CO689_RS02790 60e5c5a51af37ec0585d9b1bdef226ca 485 Pfam PF07690 Major Facilitator Superfamily 20 410 1.7E-48 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CO689_RS02790 60e5c5a51af37ec0585d9b1bdef226ca 485 Gene3D G3DSA:1.20.1250.20 3 199 4.7E-36 T 28-03-2018 CO689_RS02790 60e5c5a51af37ec0585d9b1bdef226ca 485 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 15 425 1.1E-95 T 28-03-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 CO689_RS02790 60e5c5a51af37ec0585d9b1bdef226ca 485 Gene3D G3DSA:1.20.1250.20 253 485 2.1E-31 T 28-03-2018 CO689_RS05475 9951f29f35ee0d1b9dbec0b672975f5a 372 PIRSF PIRSF000183 1 372 5.5E-157 T 28-03-2018 IPR008141 Alanine dehydrogenase GO:0000286|GO:0042853 KEGG: 00250+1.4.1.1|KEGG: 00430+1.4.1.1 CO689_RS05475 9951f29f35ee0d1b9dbec0b672975f5a 372 TIGRFAM TIGR00518 alaDH: alanine dehydrogenase 1 369 2.1E-120 T 28-03-2018 IPR008141 Alanine dehydrogenase GO:0000286|GO:0042853 KEGG: 00250+1.4.1.1|KEGG: 00430+1.4.1.1 CO689_RS05475 9951f29f35ee0d1b9dbec0b672975f5a 372 SUPERFAMILY SSF52283 1 134 5.95E-53 T 28-03-2018 CO689_RS05475 9951f29f35ee0d1b9dbec0b672975f5a 372 SUPERFAMILY SSF52283 306 360 5.95E-53 T 28-03-2018 CO689_RS05475 9951f29f35ee0d1b9dbec0b672975f5a 372 SMART SM01002 146 298 3.1E-60 T 28-03-2018 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain CO689_RS05475 9951f29f35ee0d1b9dbec0b672975f5a 372 SUPERFAMILY SSF51735 134 304 5.42E-35 T 28-03-2018 IPR016040 NAD(P)-binding domain CO689_RS05475 9951f29f35ee0d1b9dbec0b672975f5a 372 SMART SM01003 4 134 4.0E-60 T 28-03-2018 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal CO689_RS05475 9951f29f35ee0d1b9dbec0b672975f5a 372 Pfam PF05222 Alanine dehydrogenase/PNT, N-terminal domain 4 134 7.7E-40 T 28-03-2018 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal CO689_RS05475 9951f29f35ee0d1b9dbec0b672975f5a 372 Gene3D G3DSA:3.40.50.720 1 193 3.6E-39 T 28-03-2018 CO689_RS05475 9951f29f35ee0d1b9dbec0b672975f5a 372 Gene3D G3DSA:3.40.50.720 194 372 3.1E-36 T 28-03-2018 CO689_RS05475 9951f29f35ee0d1b9dbec0b672975f5a 372 Pfam PF01262 Alanine dehydrogenase/PNT, C-terminal domain 139 353 1.9E-71 T 28-03-2018 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain CO689_RS08080 b2fbc437d132eb6ad3fbe3ab5170b85f 393 Gene3D G3DSA:3.40.630.10 3 246 6.0E-48 T 28-03-2018 CO689_RS08080 b2fbc437d132eb6ad3fbe3ab5170b85f 393 Gene3D G3DSA:3.40.630.10 249 384 7.6E-18 T 28-03-2018 CO689_RS08080 b2fbc437d132eb6ad3fbe3ab5170b85f 393 PIRSF PIRSF005962 3 388 3.8E-128 T 28-03-2018 IPR017439 Amidohydrolase GO:0016787 CO689_RS08080 b2fbc437d132eb6ad3fbe3ab5170b85f 393 SUPERFAMILY SSF53187 5 198 7.48E-84 T 28-03-2018 CO689_RS08080 b2fbc437d132eb6ad3fbe3ab5170b85f 393 SUPERFAMILY SSF53187 299 381 7.48E-84 T 28-03-2018 CO689_RS08080 b2fbc437d132eb6ad3fbe3ab5170b85f 393 SUPERFAMILY SSF55031 185 296 3.66E-28 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain CO689_RS08080 b2fbc437d132eb6ad3fbe3ab5170b85f 393 Pfam PF07687 Peptidase dimerisation domain 187 280 6.7E-10 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain CO689_RS08080 b2fbc437d132eb6ad3fbe3ab5170b85f 393 Pfam PF01546 Peptidase family M20/M25/M40 73 369 3.1E-31 T 28-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CO689_RS08080 b2fbc437d132eb6ad3fbe3ab5170b85f 393 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 15 374 6.7E-115 T 28-03-2018 IPR017439 Amidohydrolase GO:0016787 CO689_RS01125 b75a11a7d3ccbb23d9fbe6502daff43b 349 Gene3D G3DSA:3.40.140.10 1 118 2.7E-27 T 28-03-2018 CO689_RS01125 b75a11a7d3ccbb23d9fbe6502daff43b 349 SUPERFAMILY SSF53927 3 137 1.16E-35 T 28-03-2018 IPR016193 Cytidine deaminase-like GO:0003824 CO689_RS01125 b75a11a7d3ccbb23d9fbe6502daff43b 349 TIGRFAM TIGR00227 ribD_Cterm: riboflavin-specific deaminase C-terminal domain 141 346 2.1E-49 T 28-03-2018 IPR011549 Riboflavin-specific deaminase, C-terminal GO:0008703|GO:0009231|GO:0050661|GO:0055114 CO689_RS01125 b75a11a7d3ccbb23d9fbe6502daff43b 349 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 3 98 5.9E-18 T 28-03-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain CO689_RS01125 b75a11a7d3ccbb23d9fbe6502daff43b 349 TIGRFAM TIGR00326 eubact_ribD: riboflavin biosynthesis protein RibD 6 343 8.4E-98 T 28-03-2018 IPR004794 Riboflavin biosynthesis protein RibD GO:0008835|GO:0009231|GO:0055114 KEGG: 00040+1.1.1.19|KEGG: 00053+1.1.1.19|KEGG: 00740+3.5.4.26+1.1.1.193|MetaCyc: PWY-5525 CO689_RS01125 b75a11a7d3ccbb23d9fbe6502daff43b 349 PIRSF PIRSF006769 1 349 2.9E-98 T 28-03-2018 IPR004794 Riboflavin biosynthesis protein RibD GO:0008835|GO:0009231|GO:0055114 KEGG: 00040+1.1.1.19|KEGG: 00053+1.1.1.19|KEGG: 00740+3.5.4.26+1.1.1.193|MetaCyc: PWY-5525 CO689_RS01125 b75a11a7d3ccbb23d9fbe6502daff43b 349 SUPERFAMILY SSF53597 140 345 1.51E-50 T 28-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 CO689_RS01125 b75a11a7d3ccbb23d9fbe6502daff43b 349 Pfam PF01872 RibD C-terminal domain 142 338 1.2E-43 T 28-03-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 CO689_RS01125 b75a11a7d3ccbb23d9fbe6502daff43b 349 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 48 86 - T 28-03-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 CO689_RS01125 b75a11a7d3ccbb23d9fbe6502daff43b 349 Gene3D G3DSA:3.40.430.10 119 349 1.6E-56 T 28-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 CO689_RS08015 1ffe7cc87341dc951906f2d243101616 182 PRINTS PR00338 Transcription termination factor NUSG signature 140 155 1.2E-18 T 28-03-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 CO689_RS08015 1ffe7cc87341dc951906f2d243101616 182 PRINTS PR00338 Transcription termination factor NUSG signature 62 74 1.2E-18 T 28-03-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 CO689_RS08015 1ffe7cc87341dc951906f2d243101616 182 PRINTS PR00338 Transcription termination factor NUSG signature 158 174 1.2E-18 T 28-03-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 CO689_RS08015 1ffe7cc87341dc951906f2d243101616 182 Gene3D G3DSA:2.30.30.30 125 182 2.5E-19 T 28-03-2018 IPR014722 Ribosomal protein L2 domain 2 CO689_RS08015 1ffe7cc87341dc951906f2d243101616 182 Gene3D G3DSA:3.30.70.940 7 124 1.5E-42 T 28-03-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 CO689_RS08015 1ffe7cc87341dc951906f2d243101616 182 SMART SM00738 7 118 2.0E-47 T 28-03-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 CO689_RS08015 1ffe7cc87341dc951906f2d243101616 182 SUPERFAMILY SSF50104 126 182 2.41E-18 T 28-03-2018 IPR008991 Translation protein SH3-like domain CO689_RS08015 1ffe7cc87341dc951906f2d243101616 182 Pfam PF00467 KOW motif 131 164 1.6E-6 T 28-03-2018 IPR005824 KOW CO689_RS08015 1ffe7cc87341dc951906f2d243101616 182 Pfam PF02357 Transcription termination factor nusG 8 114 2.9E-27 T 28-03-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 CO689_RS08015 1ffe7cc87341dc951906f2d243101616 182 SUPERFAMILY SSF82679 8 119 2.75E-39 T 28-03-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 CO689_RS08015 1ffe7cc87341dc951906f2d243101616 182 ProSitePatterns PS01014 Transcription termination factor nusG signature. 165 174 - T 28-03-2018 IPR015869 Transcription antitermination protein, NusG, bacteria, conserved site CO689_RS08015 1ffe7cc87341dc951906f2d243101616 182 SMART SM00739 128 155 4.2E-5 T 28-03-2018 IPR005824 KOW CO689_RS08015 1ffe7cc87341dc951906f2d243101616 182 TIGRFAM TIGR00922 nusG: transcription termination/antitermination factor NusG 10 182 2.0E-61 T 28-03-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 CO689_RS08015 1ffe7cc87341dc951906f2d243101616 182 Hamap MF_00948 Transcription termination/antitermination protein NusG [nusG]. 7 182 27.404 T 28-03-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 CO689_RS11975 d5f3225229701bbd413f16189b2454ea 271 Gene3D G3DSA:1.20.1080.10 1 255 4.2E-81 T 28-03-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 CO689_RS11975 d5f3225229701bbd413f16189b2454ea 271 PRINTS PR00783 Major intrinsic protein family signature 81 100 1.6E-41 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 CO689_RS11975 d5f3225229701bbd413f16189b2454ea 271 PRINTS PR00783 Major intrinsic protein family signature 136 154 1.6E-41 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 CO689_RS11975 d5f3225229701bbd413f16189b2454ea 271 PRINTS PR00783 Major intrinsic protein family signature 166 188 1.6E-41 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 CO689_RS11975 d5f3225229701bbd413f16189b2454ea 271 PRINTS PR00783 Major intrinsic protein family signature 213 233 1.6E-41 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 CO689_RS11975 d5f3225229701bbd413f16189b2454ea 271 PRINTS PR00783 Major intrinsic protein family signature 2 21 1.6E-41 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 CO689_RS11975 d5f3225229701bbd413f16189b2454ea 271 PRINTS PR00783 Major intrinsic protein family signature 44 68 1.6E-41 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 CO689_RS11975 d5f3225229701bbd413f16189b2454ea 271 ProSitePatterns PS00221 MIP family signature. 62 70 - T 28-03-2018 IPR022357 Major intrinsic protein, conserved site GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 CO689_RS11975 d5f3225229701bbd413f16189b2454ea 271 PRINTS PR02019 Aquaporin-7 signature 222 233 6.7E-5 T 28-03-2018 CO689_RS11975 d5f3225229701bbd413f16189b2454ea 271 PRINTS PR02019 Aquaporin-7 signature 81 90 6.7E-5 T 28-03-2018 CO689_RS11975 d5f3225229701bbd413f16189b2454ea 271 PRINTS PR02019 Aquaporin-7 signature 37 49 6.7E-5 T 28-03-2018 CO689_RS11975 d5f3225229701bbd413f16189b2454ea 271 PRINTS PR02019 Aquaporin-7 signature 49 58 6.7E-5 T 28-03-2018 CO689_RS11975 d5f3225229701bbd413f16189b2454ea 271 TIGRFAM TIGR00861 MIP: MIP family channel proteins 6 230 4.2E-58 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 CO689_RS11975 d5f3225229701bbd413f16189b2454ea 271 Pfam PF00230 Major intrinsic protein 4 230 2.0E-44 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 CO689_RS11975 d5f3225229701bbd413f16189b2454ea 271 SUPERFAMILY SSF81338 2 234 1.16E-70 T 28-03-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 CO689_RS09330 027b3d6d88570642d3658a9cf57bd90f 396 Pfam PF00162 Phosphoglycerate kinase 6 385 3.1E-156 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CO689_RS09330 027b3d6d88570642d3658a9cf57bd90f 396 PRINTS PR00477 Phosphoglycerate kinase family signature 348 359 6.1E-92 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CO689_RS09330 027b3d6d88570642d3658a9cf57bd90f 396 PRINTS PR00477 Phosphoglycerate kinase family signature 195 214 6.1E-92 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CO689_RS09330 027b3d6d88570642d3658a9cf57bd90f 396 PRINTS PR00477 Phosphoglycerate kinase family signature 110 125 6.1E-92 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CO689_RS09330 027b3d6d88570642d3658a9cf57bd90f 396 PRINTS PR00477 Phosphoglycerate kinase family signature 142 164 6.1E-92 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CO689_RS09330 027b3d6d88570642d3658a9cf57bd90f 396 PRINTS PR00477 Phosphoglycerate kinase family signature 314 339 6.1E-92 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CO689_RS09330 027b3d6d88570642d3658a9cf57bd90f 396 PRINTS PR00477 Phosphoglycerate kinase family signature 10 26 6.1E-92 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CO689_RS09330 027b3d6d88570642d3658a9cf57bd90f 396 PRINTS PR00477 Phosphoglycerate kinase family signature 31 53 6.1E-92 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CO689_RS09330 027b3d6d88570642d3658a9cf57bd90f 396 PRINTS PR00477 Phosphoglycerate kinase family signature 371 388 6.1E-92 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CO689_RS09330 027b3d6d88570642d3658a9cf57bd90f 396 PRINTS PR00477 Phosphoglycerate kinase family signature 172 194 6.1E-92 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CO689_RS09330 027b3d6d88570642d3658a9cf57bd90f 396 Gene3D G3DSA:3.40.50.1260 3 183 1.6E-68 T 28-03-2018 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CO689_RS09330 027b3d6d88570642d3658a9cf57bd90f 396 Gene3D G3DSA:3.40.50.1260 184 383 8.5E-84 T 28-03-2018 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CO689_RS09330 027b3d6d88570642d3658a9cf57bd90f 396 PIRSF PIRSF000724 1 396 4.3E-145 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CO689_RS09330 027b3d6d88570642d3658a9cf57bd90f 396 SUPERFAMILY SSF53748 3 395 9.66E-153 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CO689_RS09330 027b3d6d88570642d3658a9cf57bd90f 396 Hamap MF_00145 Phosphoglycerate kinase [pgk]. 8 395 41.483 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CO689_RS03310 c5566684872f574c61b47045e86ec138 169 SUPERFAMILY SSF53218 8 167 4.71E-41 T 28-03-2018 IPR001453 MoaB/Mog domain CO689_RS03310 c5566684872f574c61b47045e86ec138 169 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 14 158 7.3E-38 T 28-03-2018 IPR001453 MoaB/Mog domain CO689_RS03310 c5566684872f574c61b47045e86ec138 169 ProSitePatterns PS01078 Molybdenum cofactor biosynthesis proteins signature 1. 76 89 - T 28-03-2018 IPR008284 Molybdenum cofactor biosynthesis, conserved site GO:0006777 Reactome: R-HSA-947581 CO689_RS03310 c5566684872f574c61b47045e86ec138 169 Pfam PF00994 Probable molybdopterin binding domain 17 162 4.9E-35 T 28-03-2018 IPR001453 MoaB/Mog domain CO689_RS03310 c5566684872f574c61b47045e86ec138 169 SMART SM00852 17 163 3.1E-30 T 28-03-2018 IPR001453 MoaB/Mog domain CO689_RS03310 c5566684872f574c61b47045e86ec138 169 Gene3D G3DSA:3.40.980.10 1 169 1.1E-35 T 28-03-2018 IPR001453 MoaB/Mog domain CO689_RS03310 c5566684872f574c61b47045e86ec138 169 PIRSF PIRSF006443 1 169 1.9E-64 T 28-03-2018 IPR012245 Molybdenum cofactor biosynthesis protein MoaB GO:0006777 CO689_RS02445 88d42dbf01a1033f07698a5defb4a8bd 471 SUPERFAMILY SSF52540 82 354 1.58E-89 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CO689_RS02445 88d42dbf01a1033f07698a5defb4a8bd 471 SUPERFAMILY SSF47917 352 467 6.28E-51 T 28-03-2018 CO689_RS02445 88d42dbf01a1033f07698a5defb4a8bd 471 Gene3D G3DSA:1.10.1140.10 355 465 1.1E-42 T 28-03-2018 IPR024034 ATPase, F1/V1 complex, beta/alpha subunit, C-terminal KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CO689_RS02445 88d42dbf01a1033f07698a5defb4a8bd 471 Gene3D G3DSA:2.40.10.170 1 80 1.9E-28 T 28-03-2018 CO689_RS02445 88d42dbf01a1033f07698a5defb4a8bd 471 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 136 349 3.3E-66 T 28-03-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CO689_RS02445 88d42dbf01a1033f07698a5defb4a8bd 471 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 6 78 9.5E-23 T 28-03-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CO689_RS02445 88d42dbf01a1033f07698a5defb4a8bd 471 TIGRFAM TIGR01039 atpD: ATP synthase F1, beta subunit 3 467 4.8E-255 T 28-03-2018 IPR005722 ATP synthase, F1 complex, beta subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-2151201|Reactome: R-HSA-8949613 CO689_RS02445 88d42dbf01a1033f07698a5defb4a8bd 471 Gene3D G3DSA:3.40.50.300 81 354 2.9E-91 T 28-03-2018 CO689_RS02445 88d42dbf01a1033f07698a5defb4a8bd 471 Hamap MF_01347 ATP synthase subunit beta [atpB]. 1 467 57.369 T 28-03-2018 IPR005722 ATP synthase, F1 complex, beta subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-2151201|Reactome: R-HSA-8949613 CO689_RS02445 88d42dbf01a1033f07698a5defb4a8bd 471 SMART SM00382 148 333 6.5E-8 T 28-03-2018 IPR003593 AAA+ ATPase domain CO689_RS02445 88d42dbf01a1033f07698a5defb4a8bd 471 SUPERFAMILY SSF50615 3 80 2.98E-25 T 28-03-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CO689_RS02445 88d42dbf01a1033f07698a5defb4a8bd 471 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 340 349 - T 28-03-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CO689_RS02715 3fe0ce0731b9ed78be94dc51151f4b5f 144 ProSitePatterns PS00372 PTS EIIA domains phosphorylation site signature 2. 48 64 - T 28-03-2018 IPR002178 PTS EIIA type-2 domain CO689_RS02715 3fe0ce0731b9ed78be94dc51151f4b5f 144 SUPERFAMILY SSF55804 3 141 2.35E-41 T 28-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 CO689_RS02715 3fe0ce0731b9ed78be94dc51151f4b5f 144 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 3 141 3.1E-37 T 28-03-2018 IPR002178 PTS EIIA type-2 domain CO689_RS02715 3fe0ce0731b9ed78be94dc51151f4b5f 144 Gene3D G3DSA:3.40.930.10 1 143 3.2E-37 T 28-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 CO689_RS03350 72e2b9eaaf8bae39016e39d735600062 332 SUPERFAMILY SSF47413 3 49 9.0E-11 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CO689_RS03350 72e2b9eaaf8bae39016e39d735600062 332 SMART SM00354 1 65 4.1E-8 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CO689_RS03350 72e2b9eaaf8bae39016e39d735600062 332 Pfam PF13377 Periplasmic binding protein-like domain 176 327 6.9E-26 T 28-03-2018 CO689_RS03350 72e2b9eaaf8bae39016e39d735600062 332 SUPERFAMILY SSF53822 70 327 4.93E-32 T 28-03-2018 IPR028082 Periplasmic binding protein-like I CO689_RS03350 72e2b9eaaf8bae39016e39d735600062 332 Gene3D G3DSA:1.10.10.60 2 15 0.0013 T 28-03-2018 CO689_RS03350 72e2b9eaaf8bae39016e39d735600062 332 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 3 13 1.9E-5 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CO689_RS03350 72e2b9eaaf8bae39016e39d735600062 332 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 13 23 1.9E-5 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CO689_RS03350 72e2b9eaaf8bae39016e39d735600062 332 Pfam PF00356 Bacterial regulatory proteins, lacI family 3 48 2.4E-14 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CO689_RS03350 72e2b9eaaf8bae39016e39d735600062 332 Gene3D G3DSA:3.40.50.2300 163 330 1.3E-28 T 28-03-2018 CO689_RS03350 72e2b9eaaf8bae39016e39d735600062 332 ProSitePatterns PS00356 LacI-type HTH domain signature. 4 22 - T 28-03-2018 CO689_RS03350 72e2b9eaaf8bae39016e39d735600062 332 Gene3D G3DSA:1.10.260.40 16 65 1.4E-14 T 28-03-2018 CO689_RS03350 72e2b9eaaf8bae39016e39d735600062 332 Gene3D G3DSA:3.40.50.2300 66 162 3.2E-4 T 28-03-2018 CO689_RS06110 a37a0cb101c02b13cbfbe9e17cfd0864 237 Gene3D G3DSA:3.40.1410.10 74 237 2.0E-37 T 28-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain CO689_RS06110 a37a0cb101c02b13cbfbe9e17cfd0864 237 Gene3D G3DSA:1.10.10.10 1 73 9.2E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS06110 a37a0cb101c02b13cbfbe9e17cfd0864 237 Pfam PF07702 UTRA domain 93 231 6.0E-35 T 28-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 CO689_RS06110 a37a0cb101c02b13cbfbe9e17cfd0864 237 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 45 61 4.9E-8 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CO689_RS06110 a37a0cb101c02b13cbfbe9e17cfd0864 237 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 31 45 4.9E-8 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CO689_RS06110 a37a0cb101c02b13cbfbe9e17cfd0864 237 SUPERFAMILY SSF46785 4 75 1.32E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS06110 a37a0cb101c02b13cbfbe9e17cfd0864 237 SMART SM00345 12 71 1.4E-21 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CO689_RS06110 a37a0cb101c02b13cbfbe9e17cfd0864 237 SUPERFAMILY SSF64288 60 235 1.29E-43 T 28-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain CO689_RS06110 a37a0cb101c02b13cbfbe9e17cfd0864 237 Pfam PF00392 Bacterial regulatory proteins, gntR family 8 71 6.7E-22 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CO689_RS06110 a37a0cb101c02b13cbfbe9e17cfd0864 237 SMART SM00866 92 231 5.9E-33 T 28-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 CO689_RS06395 23ce8e2a032cd5ead41cb4df097b77da 286 Gene3D G3DSA:1.10.10.10 1 73 4.2E-8 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS00550 98bb0690a87911be4bd4fc1c67bb5a0f 308 Pfam PF06970 Replication initiator protein A (RepA) N-terminus 16 90 4.3E-29 T 28-03-2018 IPR010724 Replication initiator A, N-terminal CO689_RS05210 128fe6758eb37f7867fa42b9b3dfabef 353 SUPERFAMILY SSF51445 2 233 5.05E-53 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CO689_RS05210 128fe6758eb37f7867fa42b9b3dfabef 353 Gene3D G3DSA:2.40.100.10 238 345 4.4E-28 T 28-03-2018 IPR029000 Cyclophilin-like domain CO689_RS05210 128fe6758eb37f7867fa42b9b3dfabef 353 Pfam PF05913 Bacterial protein of unknown function (DUF871) 3 343 2.4E-93 T 28-03-2018 IPR008589 Protein of unknown function DUF871, prokaryotic CO689_RS05210 128fe6758eb37f7867fa42b9b3dfabef 353 Gene3D G3DSA:3.20.20.70 2 232 3.1E-62 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CO689_RS05210 128fe6758eb37f7867fa42b9b3dfabef 353 SUPERFAMILY SSF50891 236 344 1.55E-24 T 28-03-2018 IPR029000 Cyclophilin-like domain CO689_RS08025 508610b2f933156f7b9394609562bcf3 231 Gene3D G3DSA:3.40.50.790 68 148 1.6E-38 T 28-03-2018 IPR016095 Ribosomal protein L1, 3-layer alpha/beta-sandwich CO689_RS08025 508610b2f933156f7b9394609562bcf3 231 Hamap MF_01318_B 50S ribosomal protein L1 [rplA]. 2 229 44.489 T 28-03-2018 IPR005878 Ribosomal protein L1, bacterial-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 CO689_RS08025 508610b2f933156f7b9394609562bcf3 231 Gene3D G3DSA:3.30.190.20 149 228 1.5E-21 T 28-03-2018 CO689_RS08025 508610b2f933156f7b9394609562bcf3 231 TIGRFAM TIGR01169 rplA_bact: ribosomal protein uL1 3 228 9.4E-107 T 28-03-2018 IPR005878 Ribosomal protein L1, bacterial-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 CO689_RS08025 508610b2f933156f7b9394609562bcf3 231 SUPERFAMILY SSF56808 6 226 1.22E-86 T 28-03-2018 IPR023674 Ribosomal protein L1-like CO689_RS08025 508610b2f933156f7b9394609562bcf3 231 PIRSF PIRSF002155 1 227 1.1E-81 T 28-03-2018 IPR002143 Ribosomal protein L1 GO:0003723|GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CO689_RS08025 508610b2f933156f7b9394609562bcf3 231 ProSitePatterns PS01199 Ribosomal protein L1 signature. 121 139 - T 28-03-2018 IPR023673 Ribosomal protein L1, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CO689_RS08025 508610b2f933156f7b9394609562bcf3 231 Pfam PF00687 Ribosomal protein L1p/L10e family 31 220 5.9E-56 T 28-03-2018 IPR028364 Ribosomal protein L1/ribosomal biogenesis protein CO689_RS02160 0f06407ac09aec79f9eabc33c3bebd79 341 Gene3D G3DSA:3.30.420.40 5 147 6.9E-43 T 28-03-2018 CO689_RS02160 0f06407ac09aec79f9eabc33c3bebd79 341 ProSitePatterns PS01016 Glycoprotease family signature. 100 120 - T 28-03-2018 IPR017860 Peptidase M22, conserved site KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618|Reactome: R-HSA-6782315 CO689_RS02160 0f06407ac09aec79f9eabc33c3bebd79 341 Gene3D G3DSA:3.30.420.40 148 293 3.8E-20 T 28-03-2018 CO689_RS02160 0f06407ac09aec79f9eabc33c3bebd79 341 TIGRFAM TIGR00329 gcp_kae1: metallohydrolase, glycoprotease/Kae1 family 8 310 9.4E-110 T 28-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CO689_RS02160 0f06407ac09aec79f9eabc33c3bebd79 341 SUPERFAMILY SSF53067 105 312 9.18E-42 T 28-03-2018 CO689_RS02160 0f06407ac09aec79f9eabc33c3bebd79 341 TIGRFAM TIGR03723 T6A_TsaD_YgjD: tRNA threonylcarbamoyl adenosine modification protein TsaD 7 317 1.3E-134 T 28-03-2018 IPR022450 tRNA N6-adenosine threonylcarbamoyltransferase, TsaD GO:0002949|GO:0004222 KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CO689_RS02160 0f06407ac09aec79f9eabc33c3bebd79 341 SUPERFAMILY SSF53067 6 125 7.23E-30 T 28-03-2018 CO689_RS02160 0f06407ac09aec79f9eabc33c3bebd79 341 Hamap MF_01445 tRNA N6-adenosine threonylcarbamoyltransferase [tsaD]. 5 335 62.835 T 28-03-2018 IPR022450 tRNA N6-adenosine threonylcarbamoyltransferase, TsaD GO:0002949|GO:0004222 KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CO689_RS02160 0f06407ac09aec79f9eabc33c3bebd79 341 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 267 276 2.1E-49 T 28-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CO689_RS02160 0f06407ac09aec79f9eabc33c3bebd79 341 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 134 146 2.1E-49 T 28-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CO689_RS02160 0f06407ac09aec79f9eabc33c3bebd79 341 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 80 100 2.1E-49 T 28-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CO689_RS02160 0f06407ac09aec79f9eabc33c3bebd79 341 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 8 21 2.1E-49 T 28-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CO689_RS02160 0f06407ac09aec79f9eabc33c3bebd79 341 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 157 178 2.1E-49 T 28-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CO689_RS02160 0f06407ac09aec79f9eabc33c3bebd79 341 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 101 120 2.1E-49 T 28-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CO689_RS02160 0f06407ac09aec79f9eabc33c3bebd79 341 Pfam PF00814 Glycoprotease family 27 310 2.2E-105 T 28-03-2018 IPR000905 Gcp-like domain KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CO689_RS11690 1afc7b3b3cf8956b9aeb2713557229e4 184 Pfam PF01765 Ribosome recycling factor 19 182 8.4E-63 T 28-03-2018 IPR023584 Ribosome recycling factor domain Reactome: R-HSA-5419276 CO689_RS11690 1afc7b3b3cf8956b9aeb2713557229e4 184 Hamap MF_00040 Ribosome-recycling factor [frr]. 2 184 27.538 T 28-03-2018 IPR002661 Ribosome recycling factor GO:0006412 Reactome: R-HSA-5419276 CO689_RS11690 1afc7b3b3cf8956b9aeb2713557229e4 184 TIGRFAM TIGR00496 frr: ribosome recycling factor 11 184 1.0E-72 T 28-03-2018 IPR002661 Ribosome recycling factor GO:0006412 Reactome: R-HSA-5419276 CO689_RS11690 1afc7b3b3cf8956b9aeb2713557229e4 184 Gene3D G3DSA:1.10.132.20 1 73 3.2E-9 T 28-03-2018 CO689_RS11690 1afc7b3b3cf8956b9aeb2713557229e4 184 Gene3D G3DSA:1.10.132.20 74 183 5.7E-38 T 28-03-2018 CO689_RS11690 1afc7b3b3cf8956b9aeb2713557229e4 184 SUPERFAMILY SSF55194 2 182 7.98E-68 T 28-03-2018 IPR023584 Ribosome recycling factor domain Reactome: R-HSA-5419276 CO689_RS10725 c8e69d9ddbcc11cab309c6f98939aeb2 234 ProSitePatterns PS01057 SAICAR synthetase signature 1. 83 97 - T 28-03-2018 IPR018236 SAICAR synthetase, conserved site GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CO689_RS10725 c8e69d9ddbcc11cab309c6f98939aeb2 234 Gene3D G3DSA:3.30.470.20 91 218 3.9E-49 T 28-03-2018 CO689_RS10725 c8e69d9ddbcc11cab309c6f98939aeb2 234 Gene3D G3DSA:3.30.200.20 1 90 3.9E-27 T 28-03-2018 CO689_RS10725 c8e69d9ddbcc11cab309c6f98939aeb2 234 Hamap MF_00137 Phosphoribosylaminoimidazole-succinocarboxamide synthase [purC]. 1 232 32.017 T 28-03-2018 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CO689_RS10725 c8e69d9ddbcc11cab309c6f98939aeb2 234 Pfam PF01259 SAICAR synthetase 4 225 4.1E-62 T 28-03-2018 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CO689_RS10725 c8e69d9ddbcc11cab309c6f98939aeb2 234 TIGRFAM TIGR00081 purC: phosphoribosylaminoimidazolesuccinocarboxamide synthase 4 213 5.7E-71 T 28-03-2018 IPR001636 Phosphoribosylaminoimidazole-succinocarboxamide synthase GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234 CO689_RS10725 c8e69d9ddbcc11cab309c6f98939aeb2 234 SUPERFAMILY SSF56104 2 231 3.6E-78 T 28-03-2018 CO689_RS06780 bec438d6eb9478653b56f12017ae601f 644 Gene3D G3DSA:2.70.150.10 3 245 2.7E-33 T 28-03-2018 CO689_RS06780 bec438d6eb9478653b56f12017ae601f 644 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 347 353 - T 28-03-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 CO689_RS06780 bec438d6eb9478653b56f12017ae601f 644 SUPERFAMILY SSF81665 94 147 3.14E-13 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CO689_RS06780 bec438d6eb9478653b56f12017ae601f 644 SUPERFAMILY SSF81665 245 339 3.14E-13 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CO689_RS06780 bec438d6eb9478653b56f12017ae601f 644 SUPERFAMILY SSF81665 583 616 3.14E-13 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CO689_RS06780 bec438d6eb9478653b56f12017ae601f 644 SUPERFAMILY SSF81653 152 244 1.11E-24 T 28-03-2018 IPR008250 P-type ATPase, A domain Reactome: R-HSA-936837 CO689_RS06780 bec438d6eb9478653b56f12017ae601f 644 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 117 616 8.7E-87 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CO689_RS06780 bec438d6eb9478653b56f12017ae601f 644 Gene3D G3DSA:3.40.50.1000 464 605 2.0E-34 T 28-03-2018 IPR023214 HAD-like domain CO689_RS06780 bec438d6eb9478653b56f12017ae601f 644 SUPERFAMILY SSF56784 344 363 4.04E-55 T 28-03-2018 IPR023214 HAD-like domain CO689_RS06780 bec438d6eb9478653b56f12017ae601f 644 SUPERFAMILY SSF56784 435 637 4.04E-55 T 28-03-2018 IPR023214 HAD-like domain CO689_RS06780 bec438d6eb9478653b56f12017ae601f 644 Pfam PF00702 haloacid dehalogenase-like hydrolase 341 552 5.3E-38 T 28-03-2018 CO689_RS06780 bec438d6eb9478653b56f12017ae601f 644 Pfam PF00122 E1-E2 ATPase 143 325 1.0E-44 T 28-03-2018 CO689_RS06780 bec438d6eb9478653b56f12017ae601f 644 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 94 640 1.4E-168 T 28-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 CO689_RS06780 bec438d6eb9478653b56f12017ae601f 644 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 538 557 1.4E-28 T 28-03-2018 CO689_RS06780 bec438d6eb9478653b56f12017ae601f 644 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 463 474 1.4E-28 T 28-03-2018 CO689_RS06780 bec438d6eb9478653b56f12017ae601f 644 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 485 495 1.4E-28 T 28-03-2018 CO689_RS06780 bec438d6eb9478653b56f12017ae601f 644 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 194 208 1.4E-28 T 28-03-2018 CO689_RS06780 bec438d6eb9478653b56f12017ae601f 644 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 561 573 1.4E-28 T 28-03-2018 CO689_RS06780 bec438d6eb9478653b56f12017ae601f 644 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 345 359 1.4E-28 T 28-03-2018 CO689_RS06780 bec438d6eb9478653b56f12017ae601f 644 Gene3D G3DSA:3.40.1110.10 356 463 1.6E-19 T 28-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 CO689_RS06780 bec438d6eb9478653b56f12017ae601f 644 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 538 554 2.6E-8 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CO689_RS06780 bec438d6eb9478653b56f12017ae601f 644 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 569 594 2.6E-8 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CO689_RS06780 bec438d6eb9478653b56f12017ae601f 644 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 510 526 2.6E-8 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CO689_RS07680 a093c4f7a1747576ec2d2e3b70d7e56a 183 Gene3D G3DSA:3.40.1360.20 1 124 1.1E-18 T 28-03-2018 CO689_RS07680 a093c4f7a1747576ec2d2e3b70d7e56a 183 SMART SM00493 4 77 0.0011 T 28-03-2018 IPR006171 TOPRIM domain CO689_RS07680 a093c4f7a1747576ec2d2e3b70d7e56a 183 SUPERFAMILY SSF110455 1 113 1.65E-36 T 28-03-2018 CO689_RS07680 a093c4f7a1747576ec2d2e3b70d7e56a 183 TIGRFAM TIGR00334 5S_RNA_mat_M5: ribonuclease M5 2 175 6.0E-55 T 28-03-2018 IPR004466 Ribonuclease M5 GO:0043822 CO689_RS07680 a093c4f7a1747576ec2d2e3b70d7e56a 183 Pfam PF13331 Domain of unknown function (DUF4093) 91 175 2.0E-27 T 28-03-2018 IPR025156 Ribonuclease M5, C-terminal domain CO689_RS07680 a093c4f7a1747576ec2d2e3b70d7e56a 183 Hamap MF_01469 Ribonuclease M5 [rnmV]. 2 177 30.601 T 28-03-2018 IPR004466 Ribonuclease M5 GO:0043822 CO689_RS03220 423036c0753368e35d0ffc3e57bac91b 1045 Gene3D G3DSA:1.20.1640.10 815 1028 9.6E-40 T 28-03-2018 CO689_RS03220 423036c0753368e35d0ffc3e57bac91b 1045 Gene3D G3DSA:1.20.1640.10 291 517 7.7E-47 T 28-03-2018 CO689_RS03220 423036c0753368e35d0ffc3e57bac91b 1045 SUPERFAMILY SSF82866 313 515 6.54E-41 T 28-03-2018 CO689_RS03220 423036c0753368e35d0ffc3e57bac91b 1045 Gene3D G3DSA:3.30.2090.10 180 290 3.0E-11 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CO689_RS03220 423036c0753368e35d0ffc3e57bac91b 1045 PRINTS PR00702 Acriflavin resistance protein family signature 40 58 3.2E-43 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CO689_RS03220 423036c0753368e35d0ffc3e57bac91b 1045 PRINTS PR00702 Acriflavin resistance protein family signature 12 36 3.2E-43 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CO689_RS03220 423036c0753368e35d0ffc3e57bac91b 1045 PRINTS PR00702 Acriflavin resistance protein family signature 379 400 3.2E-43 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CO689_RS03220 423036c0753368e35d0ffc3e57bac91b 1045 PRINTS PR00702 Acriflavin resistance protein family signature 463 486 3.2E-43 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CO689_RS03220 423036c0753368e35d0ffc3e57bac91b 1045 PRINTS PR00702 Acriflavin resistance protein family signature 352 375 3.2E-43 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CO689_RS03220 423036c0753368e35d0ffc3e57bac91b 1045 PRINTS PR00702 Acriflavin resistance protein family signature 407 431 3.2E-43 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CO689_RS03220 423036c0753368e35d0ffc3e57bac91b 1045 PRINTS PR00702 Acriflavin resistance protein family signature 488 511 3.2E-43 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CO689_RS03220 423036c0753368e35d0ffc3e57bac91b 1045 Gene3D G3DSA:3.30.70.1430 42 142 4.2E-19 T 28-03-2018 CO689_RS03220 423036c0753368e35d0ffc3e57bac91b 1045 SUPERFAMILY SSF82693 291 330 1.36E-10 T 28-03-2018 CO689_RS03220 423036c0753368e35d0ffc3e57bac91b 1045 SUPERFAMILY SSF82693 135 181 1.36E-10 T 28-03-2018 CO689_RS03220 423036c0753368e35d0ffc3e57bac91b 1045 Gene3D G3DSA:3.30.2090.10 722 809 3.6E-14 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CO689_RS03220 423036c0753368e35d0ffc3e57bac91b 1045 SUPERFAMILY SSF82693 43 131 1.46E-14 T 28-03-2018 CO689_RS03220 423036c0753368e35d0ffc3e57bac91b 1045 SUPERFAMILY SSF82866 807 1028 5.23E-44 T 28-03-2018 CO689_RS03220 423036c0753368e35d0ffc3e57bac91b 1045 SUPERFAMILY SSF82714 723 805 2.88E-11 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CO689_RS03220 423036c0753368e35d0ffc3e57bac91b 1045 Pfam PF00873 AcrB/AcrD/AcrF family 6 1025 2.0E-198 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CO689_RS03220 423036c0753368e35d0ffc3e57bac91b 1045 SUPERFAMILY SSF82714 183 289 4.45E-6 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CO689_RS08775 b541adfe7df97c66ebb435e3ebf2535b 312 TIGRFAM TIGR01763 MalateDH_bact: malate dehydrogenase, NAD-dependent 4 306 8.1E-134 T 28-03-2018 IPR011275 Malate dehydrogenase, type 3 GO:0016616|GO:0055114 KEGG: 00020+1.1.1.37|KEGG: 00270+1.1.1.37|KEGG: 00620+1.1.1.37|KEGG: 00630+1.1.1.37|KEGG: 00680+1.1.1.37|KEGG: 00710+1.1.1.37|KEGG: 00720+1.1.1.37|MetaCyc: PWY-1622|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7115|MetaCyc: PWY-7383 CO689_RS08775 b541adfe7df97c66ebb435e3ebf2535b 312 SUPERFAMILY SSF56327 149 306 5.04E-54 T 28-03-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 CO689_RS08775 b541adfe7df97c66ebb435e3ebf2535b 312 Pfam PF00056 lactate/malate dehydrogenase, NAD binding domain 5 145 6.4E-40 T 28-03-2018 IPR001236 Lactate/malate dehydrogenase, N-terminal GO:0016491|GO:0055114 CO689_RS08775 b541adfe7df97c66ebb435e3ebf2535b 312 PIRSF PIRSF000102 1 312 1.7E-104 T 28-03-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 CO689_RS08775 b541adfe7df97c66ebb435e3ebf2535b 312 PRINTS PR00086 L-lactate dehydrogenase signature 31 55 6.6E-29 T 28-03-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 CO689_RS08775 b541adfe7df97c66ebb435e3ebf2535b 312 PRINTS PR00086 L-lactate dehydrogenase signature 119 139 6.6E-29 T 28-03-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 CO689_RS08775 b541adfe7df97c66ebb435e3ebf2535b 312 PRINTS PR00086 L-lactate dehydrogenase signature 173 186 6.6E-29 T 28-03-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 CO689_RS08775 b541adfe7df97c66ebb435e3ebf2535b 312 PRINTS PR00086 L-lactate dehydrogenase signature 5 29 6.6E-29 T 28-03-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 CO689_RS08775 b541adfe7df97c66ebb435e3ebf2535b 312 PRINTS PR00086 L-lactate dehydrogenase signature 143 161 6.6E-29 T 28-03-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 CO689_RS08775 b541adfe7df97c66ebb435e3ebf2535b 312 Gene3D G3DSA:3.40.50.720 5 147 9.0E-38 T 28-03-2018 CO689_RS08775 b541adfe7df97c66ebb435e3ebf2535b 312 Hamap MF_00487 Malate dehydrogenase [mdh]. 4 310 44.684 T 28-03-2018 IPR011275 Malate dehydrogenase, type 3 GO:0016616|GO:0055114 KEGG: 00020+1.1.1.37|KEGG: 00270+1.1.1.37|KEGG: 00620+1.1.1.37|KEGG: 00630+1.1.1.37|KEGG: 00680+1.1.1.37|KEGG: 00710+1.1.1.37|KEGG: 00720+1.1.1.37|MetaCyc: PWY-1622|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7115|MetaCyc: PWY-7383 CO689_RS08775 b541adfe7df97c66ebb435e3ebf2535b 312 SUPERFAMILY SSF51735 5 145 6.61E-45 T 28-03-2018 IPR016040 NAD(P)-binding domain CO689_RS08775 b541adfe7df97c66ebb435e3ebf2535b 312 Pfam PF02866 lactate/malate dehydrogenase, alpha/beta C-terminal domain 150 304 1.2E-29 T 28-03-2018 IPR022383 Lactate/malate dehydrogenase, C-terminal GO:0016616|GO:0055114 CO689_RS08775 b541adfe7df97c66ebb435e3ebf2535b 312 Gene3D G3DSA:3.90.110.10 148 311 1.1E-51 T 28-03-2018 CO689_RS06210 54f262a191726c4d5a9304ca67d0b9c2 432 PIRSF PIRSF032522 339 405 91.0 T 28-03-2018 IPR023599 Membrane-associated protein TcaA GO:0016021|GO:0046677 CO689_RS06210 54f262a191726c4d5a9304ca67d0b9c2 432 PIRSF PIRSF032522 1 350 9.7E-42 T 28-03-2018 IPR023599 Membrane-associated protein TcaA GO:0016021|GO:0046677 CO689_RS06210 54f262a191726c4d5a9304ca67d0b9c2 432 Pfam PF13240 zinc-ribbon domain 3 24 8.1E-7 T 28-03-2018 IPR026870 Zinc-ribbon domain Reactome: R-HSA-202670 CO689_RS06210 54f262a191726c4d5a9304ca67d0b9c2 432 Gene3D G3DSA:3.30.40.10 1 97 0.0017 T 28-03-2018 IPR013083 Zinc finger, RING/FYVE/PHD-type CO689_RS13300 a40253cd429f433068d46796171d4d2e 611 SUPERFAMILY SSF53067 1 157 6.64E-56 T 28-03-2018 CO689_RS13300 a40253cd429f433068d46796171d4d2e 611 SUPERFAMILY SSF53067 161 351 7.07E-68 T 28-03-2018 CO689_RS13300 a40253cd429f433068d46796171d4d2e 611 Gene3D G3DSA:1.20.1270.10 502 588 7.8E-24 T 28-03-2018 IPR029048 Heat shock protein 70kD, C-terminal domain CO689_RS13300 a40253cd429f433068d46796171d4d2e 611 Pfam PF00012 Hsp70 protein 4 574 6.0E-248 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CO689_RS13300 a40253cd429f433068d46796171d4d2e 611 Gene3D G3DSA:3.30.420.40 172 336 2.0E-50 T 28-03-2018 CO689_RS13300 a40253cd429f433068d46796171d4d2e 611 Gene3D G3DSA:2.60.34.10 360 501 1.4E-65 T 28-03-2018 IPR029047 Heat shock protein 70kD, peptide-binding domain Reactome: R-HSA-3371453 CO689_RS13300 a40253cd429f433068d46796171d4d2e 611 SUPERFAMILY SSF100920 354 510 9.29E-61 T 28-03-2018 IPR029047 Heat shock protein 70kD, peptide-binding domain Reactome: R-HSA-3371453 CO689_RS13300 a40253cd429f433068d46796171d4d2e 611 Gene3D G3DSA:3.30.420.40 1 171 1.3E-67 T 28-03-2018 CO689_RS13300 a40253cd429f433068d46796171d4d2e 611 SUPERFAMILY SSF100934 477 574 3.73E-14 T 28-03-2018 IPR029048 Heat shock protein 70kD, C-terminal domain CO689_RS13300 a40253cd429f433068d46796171d4d2e 611 ProSitePatterns PS00329 Heat shock hsp70 proteins family signature 2. 166 179 - T 28-03-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 CO689_RS13300 a40253cd429f433068d46796171d4d2e 611 TIGRFAM TIGR02350 prok_dnaK: chaperone protein DnaK 3 574 6.9E-286 T 28-03-2018 IPR012725 Chaperone DnaK GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-1268020|Reactome: R-HSA-3371453|Reactome: R-HSA-8949613 CO689_RS13300 a40253cd429f433068d46796171d4d2e 611 ProSitePatterns PS00297 Heat shock hsp70 proteins family signature 1. 7 14 - T 28-03-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 CO689_RS13300 a40253cd429f433068d46796171d4d2e 611 PRINTS PR00301 70kDa heat shock protein signature 53 61 7.0E-78 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CO689_RS13300 a40253cd429f433068d46796171d4d2e 611 PRINTS PR00301 70kDa heat shock protein signature 304 320 7.0E-78 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CO689_RS13300 a40253cd429f433068d46796171d4d2e 611 PRINTS PR00301 70kDa heat shock protein signature 358 377 7.0E-78 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CO689_RS13300 a40253cd429f433068d46796171d4d2e 611 PRINTS PR00301 70kDa heat shock protein signature 439 455 7.0E-78 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CO689_RS13300 a40253cd429f433068d46796171d4d2e 611 PRINTS PR00301 70kDa heat shock protein signature 3 16 7.0E-78 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CO689_RS13300 a40253cd429f433068d46796171d4d2e 611 PRINTS PR00301 70kDa heat shock protein signature 172 182 7.0E-78 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CO689_RS13300 a40253cd429f433068d46796171d4d2e 611 PRINTS PR00301 70kDa heat shock protein signature 31 43 7.0E-78 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CO689_RS13300 a40253cd429f433068d46796171d4d2e 611 PRINTS PR00301 70kDa heat shock protein signature 335 355 7.0E-78 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CO689_RS13300 a40253cd429f433068d46796171d4d2e 611 PRINTS PR00301 70kDa heat shock protein signature 112 132 7.0E-78 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CO689_RS13300 a40253cd429f433068d46796171d4d2e 611 ProSitePatterns PS01036 Heat shock hsp70 proteins family signature 3. 307 321 - T 28-03-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 CO689_RS13300 a40253cd429f433068d46796171d4d2e 611 Hamap MF_00332 Chaperone protein DnaK [dnaK]. 1 602 37.035 T 28-03-2018 IPR012725 Chaperone DnaK GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-1268020|Reactome: R-HSA-3371453|Reactome: R-HSA-8949613 CO689_RS11355 39762a7c8b0f2983407aa5e160244b2e 254 Pfam PF00175 Oxidoreductase NAD-binding domain 108 198 1.3E-6 T 28-03-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 CO689_RS11355 39762a7c8b0f2983407aa5e160244b2e 254 PRINTS PR00409 Phthalate dioxygenase reductase family signature 184 192 8.9E-5 T 28-03-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 CO689_RS11355 39762a7c8b0f2983407aa5e160244b2e 254 PRINTS PR00409 Phthalate dioxygenase reductase family signature 107 126 8.9E-5 T 28-03-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 CO689_RS11355 39762a7c8b0f2983407aa5e160244b2e 254 Hamap MF_01211 Dihydroorotate dehydrogenase B (NAD(+)), electron transfer subunit [pyrK]. 1 254 37.331 T 28-03-2018 IPR023455 Dihydroorotate dehydrogenase electron transfer subunit CO689_RS11355 39762a7c8b0f2983407aa5e160244b2e 254 Pfam PF10418 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B 213 252 3.5E-16 T 28-03-2018 IPR019480 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain CO689_RS11355 39762a7c8b0f2983407aa5e160244b2e 254 SUPERFAMILY SSF52343 92 252 6.29E-37 T 28-03-2018 CO689_RS11355 39762a7c8b0f2983407aa5e160244b2e 254 Gene3D G3DSA:2.40.30.10 3 95 9.1E-13 T 28-03-2018 CO689_RS11355 39762a7c8b0f2983407aa5e160244b2e 254 SUPERFAMILY SSF63380 5 97 5.67E-19 T 28-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 CO689_RS11355 39762a7c8b0f2983407aa5e160244b2e 254 Gene3D G3DSA:2.10.240.10 213 252 7.1E-17 T 28-03-2018 IPR019480 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain CO689_RS11355 39762a7c8b0f2983407aa5e160244b2e 254 PIRSF PIRSF006816 2 254 2.2E-72 T 28-03-2018 IPR012165 Cytochrome-c3 hydrogenase, gamma subunit GO:0006221|GO:0050660|GO:0051537 CO689_RS11355 39762a7c8b0f2983407aa5e160244b2e 254 Gene3D G3DSA:3.40.50.80 101 202 2.8E-13 T 28-03-2018 CO689_RS03060 c6abe3a8f34aad4226a041346323dcf9 61 SUPERFAMILY SSF55129 1 60 6.41E-22 T 28-03-2018 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain CO689_RS03060 c6abe3a8f34aad4226a041346323dcf9 61 Gene3D G3DSA:3.30.1390.20 4 58 7.0E-25 T 28-03-2018 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain CO689_RS03060 c6abe3a8f34aad4226a041346323dcf9 61 PIRSF PIRSF002211 1 60 5.5E-29 T 28-03-2018 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CO689_RS03060 c6abe3a8f34aad4226a041346323dcf9 61 TIGRFAM TIGR01308 rpmD_bact: ribosomal protein uL30 4 58 5.0E-28 T 28-03-2018 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CO689_RS03060 c6abe3a8f34aad4226a041346323dcf9 61 Pfam PF00327 Ribosomal protein L30p/L7e 5 53 2.2E-20 T 28-03-2018 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain CO689_RS03060 c6abe3a8f34aad4226a041346323dcf9 61 Hamap MF_01371_B 50S ribosomal protein L30 [rpmD]. 1 58 20.081 T 28-03-2018 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CO689_RS13180 b45c7faf632688a6eb82e441ea01d7f9 256 SUPERFAMILY SSF52540 3 229 4.02E-60 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CO689_RS13180 b45c7faf632688a6eb82e441ea01d7f9 256 Pfam PF00005 ABC transporter 21 170 1.2E-34 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CO689_RS13180 b45c7faf632688a6eb82e441ea01d7f9 256 SMART SM00382 30 224 2.6E-18 T 28-03-2018 IPR003593 AAA+ ATPase domain CO689_RS13180 b45c7faf632688a6eb82e441ea01d7f9 256 Gene3D G3DSA:3.40.50.300 1 238 4.6E-61 T 28-03-2018 CO689_RS13180 b45c7faf632688a6eb82e441ea01d7f9 256 ProSitePatterns PS00211 ABC transporters family signature. 142 156 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CO689_RS11370 b546b80a62a2923e997a80593e2fed72 203 TIGRFAM TIGR00336 pyrE: orotate phosphoribosyltransferase 9 176 4.1E-46 T 28-03-2018 IPR004467 Orotate phosphoribosyl transferase domain GO:0004588 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CO689_RS11370 b546b80a62a2923e997a80593e2fed72 203 Pfam PF00156 Phosphoribosyl transferase domain 44 185 6.1E-20 T 28-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 CO689_RS11370 b546b80a62a2923e997a80593e2fed72 203 SUPERFAMILY SSF53271 1 199 8.92E-53 T 28-03-2018 IPR029057 Phosphoribosyltransferase-like CO689_RS11370 b546b80a62a2923e997a80593e2fed72 203 Hamap MF_01208 Orotate phosphoribosyltransferase [pyrE]. 1 203 28.117 T 28-03-2018 IPR023031 Orotate phosphoribosyltransferase GO:0004588|GO:0006221 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CO689_RS11370 b546b80a62a2923e997a80593e2fed72 203 Gene3D G3DSA:3.40.50.2020 1 203 1.5E-37 T 28-03-2018 CO689_RS08875 54f01f869970cc2a35eca598f49d6649 87 Pfam PF04226 Transglycosylase associated protein 34 78 8.5E-9 T 28-03-2018 IPR007341 Transglycosylase-associated protein GO:0016021 CO689_RS11345 ef172c14fe5be147f8a4989b1a759a91 366 SUPERFAMILY SSF52317 152 357 7.89E-56 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CO689_RS11345 ef172c14fe5be147f8a4989b1a759a91 366 Pfam PF00117 Glutamine amidotransferase class-I 176 352 6.8E-46 T 28-03-2018 IPR017926 Glutamine amidotransferase CO689_RS11345 ef172c14fe5be147f8a4989b1a759a91 366 PRINTS PR00097 Anthranilate synthase component II signature 243 254 2.5E-6 T 28-03-2018 CO689_RS11345 ef172c14fe5be147f8a4989b1a759a91 366 PRINTS PR00097 Anthranilate synthase component II signature 216 225 2.5E-6 T 28-03-2018 CO689_RS11345 ef172c14fe5be147f8a4989b1a759a91 366 PRINTS PR00097 Anthranilate synthase component II signature 329 342 2.5E-6 T 28-03-2018 CO689_RS11345 ef172c14fe5be147f8a4989b1a759a91 366 PRINTS PR00096 Glutamine amidotransferase superfamily signature 243 254 2.2E-11 T 28-03-2018 CO689_RS11345 ef172c14fe5be147f8a4989b1a759a91 366 PRINTS PR00096 Glutamine amidotransferase superfamily signature 329 342 2.2E-11 T 28-03-2018 CO689_RS11345 ef172c14fe5be147f8a4989b1a759a91 366 PRINTS PR00096 Glutamine amidotransferase superfamily signature 216 225 2.2E-11 T 28-03-2018 CO689_RS11345 ef172c14fe5be147f8a4989b1a759a91 366 Gene3D G3DSA:3.40.50.880 142 359 5.7E-51 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CO689_RS11345 ef172c14fe5be147f8a4989b1a759a91 366 SUPERFAMILY SSF52021 4 145 6.41E-53 T 28-03-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CO689_RS11345 ef172c14fe5be147f8a4989b1a759a91 366 TIGRFAM TIGR01368 CPSaseIIsmall: carbamoyl-phosphate synthase, small subunit 6 355 1.7E-141 T 28-03-2018 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CO689_RS11345 ef172c14fe5be147f8a4989b1a759a91 366 Hamap MF_01209 Carbamoyl-phosphate synthase small chain [carA]. 3 358 47.856 T 28-03-2018 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CO689_RS11345 ef172c14fe5be147f8a4989b1a759a91 366 Pfam PF00988 Carbamoyl-phosphate synthase small chain, CPSase domain 5 130 1.6E-48 T 28-03-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CO689_RS11345 ef172c14fe5be147f8a4989b1a759a91 366 Gene3D G3DSA:3.50.30.20 2 141 1.1E-53 T 28-03-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CO689_RS11345 ef172c14fe5be147f8a4989b1a759a91 366 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 243 259 1.7E-35 T 28-03-2018 CO689_RS11345 ef172c14fe5be147f8a4989b1a759a91 366 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 213 227 1.7E-35 T 28-03-2018 CO689_RS11345 ef172c14fe5be147f8a4989b1a759a91 366 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 260 277 1.7E-35 T 28-03-2018 CO689_RS11345 ef172c14fe5be147f8a4989b1a759a91 366 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 285 296 1.7E-35 T 28-03-2018 CO689_RS11345 ef172c14fe5be147f8a4989b1a759a91 366 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 174 188 1.7E-35 T 28-03-2018 CO689_RS11345 ef172c14fe5be147f8a4989b1a759a91 366 SMART SM01097 3 133 3.4E-76 T 28-03-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CO689_RS00440 b89e3b4b765e66d26836882a1699461a 175 Gene3D G3DSA:1.10.10.10 24 97 0.0086 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS08570 9f463275e53c61034ecee832e580b1c7 253 SMART SM00382 32 220 3.9E-13 T 28-03-2018 IPR003593 AAA+ ATPase domain CO689_RS08570 9f463275e53c61034ecee832e580b1c7 253 SUPERFAMILY SSF52540 3 224 1.87E-70 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CO689_RS08570 9f463275e53c61034ecee832e580b1c7 253 Pfam PF00005 ABC transporter 23 171 3.6E-34 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CO689_RS08570 9f463275e53c61034ecee832e580b1c7 253 Gene3D G3DSA:3.40.50.300 1 243 7.9E-67 T 28-03-2018 CO689_RS09800 c3bd1fdd0d41bb6284b1638f29830f36 497 Pfam PF05709 Phage tail protein 23 497 2.2E-37 T 28-03-2018 IPR008841 Siphovirus-type tail component CO689_RS11960 7e60743bfee60c392e11617eced65689 867 Gene3D G3DSA:1.10.1420.10 247 391 1.2E-37 T 28-03-2018 CO689_RS11960 7e60743bfee60c392e11617eced65689 867 Pfam PF05192 MutS domain III 256 546 6.8E-44 T 28-03-2018 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 CO689_RS11960 7e60743bfee60c392e11617eced65689 867 Pfam PF05190 MutS family domain IV 412 505 1.7E-27 T 28-03-2018 IPR007861 DNA mismatch repair protein MutS, clamp GO:0005524|GO:0006298|GO:0030983 CO689_RS11960 7e60743bfee60c392e11617eced65689 867 Hamap MF_00096 DNA mismatch repair protein MutS [mutS]. 4 858 25.099 T 28-03-2018 IPR005748 DNA mismatch repair protein MutS GO:0005524|GO:0006298|GO:0030983 CO689_RS11960 7e60743bfee60c392e11617eced65689 867 TIGRFAM TIGR01070 mutS1: DNA mismatch repair protein MutS 5 863 0.0 T 28-03-2018 IPR005748 DNA mismatch repair protein MutS GO:0005524|GO:0006298|GO:0030983 CO689_RS11960 7e60743bfee60c392e11617eced65689 867 Gene3D G3DSA:3.40.50.300 554 825 2.1E-43 T 28-03-2018 CO689_RS11960 7e60743bfee60c392e11617eced65689 867 Pfam PF01624 MutS domain I 5 115 5.7E-48 T 28-03-2018 IPR007695 DNA mismatch repair protein MutS-like, N-terminal GO:0005524|GO:0006298|GO:0030983 Reactome: R-HSA-5632928 CO689_RS11960 7e60743bfee60c392e11617eced65689 867 Pfam PF05188 MutS domain II 125 237 1.2E-14 T 28-03-2018 IPR007860 DNA mismatch repair protein MutS, connector domain GO:0005524|GO:0006298|GO:0030983 CO689_RS11960 7e60743bfee60c392e11617eced65689 867 SUPERFAMILY SSF53150 115 264 1.44E-34 T 28-03-2018 IPR007860 DNA mismatch repair protein MutS, connector domain GO:0005524|GO:0006298|GO:0030983 CO689_RS11960 7e60743bfee60c392e11617eced65689 867 PIRSF PIRSF037677 159 849 7.8E-134 T 28-03-2018 IPR017261 DNA mismatch repair protein MutS/MSH GO:0006298|GO:0030983 CO689_RS11960 7e60743bfee60c392e11617eced65689 867 PIRSF PIRSF037677 1 167 4.9E-37 T 28-03-2018 IPR017261 DNA mismatch repair protein MutS/MSH GO:0006298|GO:0030983 CO689_RS11960 7e60743bfee60c392e11617eced65689 867 SMART SM00534 595 782 6.0E-105 T 28-03-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 CO689_RS11960 7e60743bfee60c392e11617eced65689 867 Gene3D G3DSA:3.30.420.110 129 246 1.1E-23 T 28-03-2018 IPR007860 DNA mismatch repair protein MutS, connector domain GO:0005524|GO:0006298|GO:0030983 CO689_RS11960 7e60743bfee60c392e11617eced65689 867 SUPERFAMILY SSF52540 554 785 7.93E-59 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CO689_RS11960 7e60743bfee60c392e11617eced65689 867 Gene3D G3DSA:1.10.1420.10 392 522 5.2E-28 T 28-03-2018 CO689_RS11960 7e60743bfee60c392e11617eced65689 867 SUPERFAMILY SSF55271 2 112 2.22E-45 T 28-03-2018 IPR016151 DNA mismatch repair protein MutS, N-terminal GO:0005524|GO:0006298|GO:0030983 Reactome: R-HSA-5632928 CO689_RS11960 7e60743bfee60c392e11617eced65689 867 SMART SM00533 268 578 1.7E-104 T 28-03-2018 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 CO689_RS11960 7e60743bfee60c392e11617eced65689 867 Gene3D G3DSA:3.40.1170.10 1 128 8.1E-49 T 28-03-2018 IPR016151 DNA mismatch repair protein MutS, N-terminal GO:0005524|GO:0006298|GO:0030983 Reactome: R-HSA-5632928 CO689_RS11960 7e60743bfee60c392e11617eced65689 867 Pfam PF00488 MutS domain V 599 784 5.3E-81 T 28-03-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 CO689_RS11960 7e60743bfee60c392e11617eced65689 867 SUPERFAMILY SSF48334 251 553 1.31E-84 T 28-03-2018 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 CO689_RS11960 7e60743bfee60c392e11617eced65689 867 ProSitePatterns PS00486 DNA mismatch repair proteins mutS family signature. 676 692 - T 28-03-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 CO689_RS00265 5d156420ccfe0a731abd5e01290800ff 224 Gene3D G3DSA:1.10.10.10 5 69 4.2E-5 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS00265 5d156420ccfe0a731abd5e01290800ff 224 Pfam PF13610 DDE domain 72 203 1.2E-38 T 28-03-2018 IPR032874 DDE domain CO689_RS00265 5d156420ccfe0a731abd5e01290800ff 224 Gene3D G3DSA:3.30.420.10 70 217 2.7E-16 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CO689_RS00265 5d156420ccfe0a731abd5e01290800ff 224 SUPERFAMILY SSF53098 70 216 5.82E-10 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CO689_RS00650 4baf3ce97805144c7823e2d461f7cd32 130 SUPERFAMILY SSF55811 9 111 2.17E-14 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CO689_RS00650 4baf3ce97805144c7823e2d461f7cd32 130 Gene3D G3DSA:3.90.79.10 5 124 4.2E-11 T 28-03-2018 CO689_RS00650 4baf3ce97805144c7823e2d461f7cd32 130 Pfam PF00293 NUDIX domain 14 109 4.2E-8 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 CO689_RS07395 d0c15fb10378511911795cb318d2229b 187 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 5 18 6.9E-9 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CO689_RS07395 d0c15fb10378511911795cb318d2229b 187 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 26 49 6.9E-9 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CO689_RS07395 d0c15fb10378511911795cb318d2229b 187 Gene3D G3DSA:1.10.10.60 1 37 5.0E-13 T 28-03-2018 CO689_RS07395 d0c15fb10378511911795cb318d2229b 187 Gene3D G3DSA:1.10.10.60 38 126 8.4E-7 T 28-03-2018 CO689_RS07395 d0c15fb10378511911795cb318d2229b 187 Pfam PF00440 Bacterial regulatory proteins, tetR family 5 51 7.9E-14 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CO689_RS07395 d0c15fb10378511911795cb318d2229b 187 SUPERFAMILY SSF46689 2 63 3.24E-15 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CO689_RS04575 5b80001d0e7d31063b0d63a9831854ef 140 Pfam PF00582 Universal stress protein family 1 140 2.0E-14 T 28-03-2018 IPR006016 UspA GO:0006950 CO689_RS04575 5b80001d0e7d31063b0d63a9831854ef 140 Gene3D G3DSA:3.40.50.620 2 140 1.1E-17 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CO689_RS04575 5b80001d0e7d31063b0d63a9831854ef 140 PRINTS PR01438 Universal stress protein signature 2 20 3.5E-8 T 28-03-2018 IPR006015 Universal stress protein A CO689_RS04575 5b80001d0e7d31063b0d63a9831854ef 140 PRINTS PR01438 Universal stress protein signature 100 112 3.5E-8 T 28-03-2018 IPR006015 Universal stress protein A CO689_RS04575 5b80001d0e7d31063b0d63a9831854ef 140 PRINTS PR01438 Universal stress protein signature 118 140 3.5E-8 T 28-03-2018 IPR006015 Universal stress protein A CO689_RS04575 5b80001d0e7d31063b0d63a9831854ef 140 SUPERFAMILY SSF52402 1 140 5.27E-21 T 28-03-2018 CO689_RS13440 5c6bf3c6bbed316ada36e1883d250601 804 SUPERFAMILY SSF52540 565 745 3.79E-54 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CO689_RS13440 5c6bf3c6bbed316ada36e1883d250601 804 SUPERFAMILY SSF52540 460 527 3.79E-54 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CO689_RS13440 5c6bf3c6bbed316ada36e1883d250601 804 Gene3D G3DSA:1.10.150.280 81 159 1.9E-5 T 28-03-2018 CO689_RS13440 5c6bf3c6bbed316ada36e1883d250601 804 Gene3D G3DSA:1.10.150.280 161 220 0.19 T 28-03-2018 CO689_RS13440 5c6bf3c6bbed316ada36e1883d250601 804 SUPERFAMILY SSF52540 191 509 3.11E-41 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CO689_RS13440 5c6bf3c6bbed316ada36e1883d250601 804 TIGRFAM TIGR01448 recD_rel: helicase, RecD/TraA family 12 744 7.7E-302 T 28-03-2018 IPR006345 DNA helicase, RecD-like GO:0003677|GO:0032508|GO:0043141 CO689_RS13440 5c6bf3c6bbed316ada36e1883d250601 804 Gene3D G3DSA:3.40.50.300 295 521 7.7E-34 T 28-03-2018 CO689_RS13440 5c6bf3c6bbed316ada36e1883d250601 804 SMART SM00382 352 512 0.0012 T 28-03-2018 IPR003593 AAA+ ATPase domain CO689_RS13440 5c6bf3c6bbed316ada36e1883d250601 804 Pfam PF13604 AAA domain 339 545 1.7E-53 T 28-03-2018 CO689_RS13440 5c6bf3c6bbed316ada36e1883d250601 804 Hamap MF_01488 ATP-dependent RecD-like DNA helicase [recD2]. 9 790 29.007 T 28-03-2018 IPR006345 DNA helicase, RecD-like GO:0003677|GO:0032508|GO:0043141 CO689_RS13440 5c6bf3c6bbed316ada36e1883d250601 804 Gene3D G3DSA:3.40.50.300 522 733 8.9E-26 T 28-03-2018 CO689_RS13440 5c6bf3c6bbed316ada36e1883d250601 804 Pfam PF14490 Helix-hairpin-helix containing domain 153 243 4.9E-29 T 28-03-2018 IPR029493 RecD helicase-like helix-hairpin-helix domain CO689_RS13440 5c6bf3c6bbed316ada36e1883d250601 804 Pfam PF13538 UvrD-like helicase C-terminal domain 672 718 3.4E-15 T 28-03-2018 IPR027785 UvrD-like helicase C-terminal domain CO689_RS11075 f2e6a4e86c8ad3a53ae963b2929f9e53 570 SUPERFAMILY SSF81301 152 313 8.5E-40 T 28-03-2018 CO689_RS11075 f2e6a4e86c8ad3a53ae963b2929f9e53 570 PRINTS PR00870 DNA-polymerase family X pol beta-like signature 55 72 1.1E-5 T 28-03-2018 IPR002008 DNA polymerase family X, beta-like GO:0003677|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CO689_RS11075 f2e6a4e86c8ad3a53ae963b2929f9e53 570 PRINTS PR00870 DNA-polymerase family X pol beta-like signature 180 199 1.1E-5 T 28-03-2018 IPR002008 DNA polymerase family X, beta-like GO:0003677|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CO689_RS11075 f2e6a4e86c8ad3a53ae963b2929f9e53 570 Pfam PF02811 PHP domain 335 484 1.4E-6 T 28-03-2018 IPR004013 PHP domain GO:0003824 CO689_RS11075 f2e6a4e86c8ad3a53ae963b2929f9e53 570 Pfam PF14791 DNA polymerase beta thumb 254 313 8.9E-15 T 28-03-2018 IPR029398 DNA polymerase beta, thumb domain CO689_RS11075 f2e6a4e86c8ad3a53ae963b2929f9e53 570 Pfam PF14716 Helix-hairpin-helix domain 4 68 7.5E-19 T 28-03-2018 IPR010996 DNA polymerase beta-like, N-terminal domain CO689_RS11075 f2e6a4e86c8ad3a53ae963b2929f9e53 570 SUPERFAMILY SSF47802 3 81 1.57E-18 T 28-03-2018 IPR010996 DNA polymerase beta-like, N-terminal domain CO689_RS11075 f2e6a4e86c8ad3a53ae963b2929f9e53 570 Gene3D G3DSA:3.30.210.10 252 313 5.6E-15 T 28-03-2018 IPR029398 DNA polymerase beta, thumb domain CO689_RS11075 f2e6a4e86c8ad3a53ae963b2929f9e53 570 Gene3D G3DSA:3.30.460.10 152 245 3.8E-20 T 28-03-2018 CO689_RS11075 f2e6a4e86c8ad3a53ae963b2929f9e53 570 PIRSF PIRSF005047 1 566 2.1E-222 T 28-03-2018 IPR022311 Uncharacterised conserved protein UCP005047, YshC KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CO689_RS11075 f2e6a4e86c8ad3a53ae963b2929f9e53 570 SMART SM00278 88 107 150.0 T 28-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 CO689_RS11075 f2e6a4e86c8ad3a53ae963b2929f9e53 570 SMART SM00278 123 142 15.0 T 28-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 CO689_RS11075 f2e6a4e86c8ad3a53ae963b2929f9e53 570 SMART SM00278 48 67 640.0 T 28-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 CO689_RS11075 f2e6a4e86c8ad3a53ae963b2929f9e53 570 Gene3D G3DSA:1.10.150.20 85 146 1.2E-13 T 28-03-2018 CO689_RS11075 f2e6a4e86c8ad3a53ae963b2929f9e53 570 Pfam PF14520 Helix-hairpin-helix domain 90 141 2.2E-9 T 28-03-2018 CO689_RS11075 f2e6a4e86c8ad3a53ae963b2929f9e53 570 SMART SM00483 1 314 1.6E-45 T 28-03-2018 IPR002054 DNA-directed DNA polymerase X GO:0003677|GO:0003887 CO689_RS11075 f2e6a4e86c8ad3a53ae963b2929f9e53 570 Gene3D G3DSA:3.20.20.140 335 566 1.5E-40 T 28-03-2018 CO689_RS11075 f2e6a4e86c8ad3a53ae963b2929f9e53 570 SMART SM00481 334 413 8.2E-10 T 28-03-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal CO689_RS11075 f2e6a4e86c8ad3a53ae963b2929f9e53 570 SUPERFAMILY SSF89550 333 567 1.02E-49 T 28-03-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 CO689_RS11075 f2e6a4e86c8ad3a53ae963b2929f9e53 570 Gene3D G3DSA:1.10.150.110 1 82 2.5E-17 T 28-03-2018 CO689_RS06725 9741a1e168a08f1c3f0699db284b65d8 429 Pfam PF02040 Arsenical pump membrane protein 4 425 6.5E-195 T 28-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 CO689_RS06725 9741a1e168a08f1c3f0699db284b65d8 429 TIGRFAM TIGR00935 2a45: arsenite/antimonite efflux pump membrane protein 3 428 1.5E-223 T 28-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 CO689_RS06725 9741a1e168a08f1c3f0699db284b65d8 429 PRINTS PR00758 Arsenical pump membrane protein signature 398 422 1.0E-114 T 28-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 CO689_RS06725 9741a1e168a08f1c3f0699db284b65d8 429 PRINTS PR00758 Arsenical pump membrane protein signature 218 243 1.0E-114 T 28-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 CO689_RS06725 9741a1e168a08f1c3f0699db284b65d8 429 PRINTS PR00758 Arsenical pump membrane protein signature 102 126 1.0E-114 T 28-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 CO689_RS06725 9741a1e168a08f1c3f0699db284b65d8 429 PRINTS PR00758 Arsenical pump membrane protein signature 145 169 1.0E-114 T 28-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 CO689_RS06725 9741a1e168a08f1c3f0699db284b65d8 429 PRINTS PR00758 Arsenical pump membrane protein signature 324 346 1.0E-114 T 28-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 CO689_RS06725 9741a1e168a08f1c3f0699db284b65d8 429 PRINTS PR00758 Arsenical pump membrane protein signature 178 201 1.0E-114 T 28-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 CO689_RS06725 9741a1e168a08f1c3f0699db284b65d8 429 PRINTS PR00758 Arsenical pump membrane protein signature 279 303 1.0E-114 T 28-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 CO689_RS06725 9741a1e168a08f1c3f0699db284b65d8 429 PRINTS PR00758 Arsenical pump membrane protein signature 365 390 1.0E-114 T 28-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 CO689_RS07705 864d35d4a6f9662f2cef06ef2031ef12 126 TIGRFAM TIGR00004 TIGR00004: reactive intermediate/imine deaminase 1 122 3.6E-53 T 28-03-2018 IPR006056 RidA family CO689_RS07705 864d35d4a6f9662f2cef06ef2031ef12 126 Gene3D G3DSA:3.30.1330.40 1 125 9.8E-47 T 28-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CO689_RS07705 864d35d4a6f9662f2cef06ef2031ef12 126 Pfam PF01042 Endoribonuclease L-PSP 7 122 3.1E-47 T 28-03-2018 IPR006175 YjgF/YER057c/UK114 family CO689_RS07705 864d35d4a6f9662f2cef06ef2031ef12 126 ProSitePatterns PS01094 Uncharacterized protein family UPF0076 signature. 99 117 - T 28-03-2018 IPR019897 RidA, conserved site CO689_RS07705 864d35d4a6f9662f2cef06ef2031ef12 126 SUPERFAMILY SSF55298 2 124 1.49E-46 T 28-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CO689_RS11980 1e7463b8db906613cca04c1bc34c574a 499 Hamap MF_00186 Glycerol kinase [glpK]. 2 496 58.775 T 28-03-2018 IPR005999 Glycerol kinase GO:0004370|GO:0006072 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|Reactome: R-HSA-75109 CO689_RS11980 1e7463b8db906613cca04c1bc34c574a 499 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 4 251 4.7E-90 T 28-03-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 CO689_RS11980 1e7463b8db906613cca04c1bc34c574a 499 Gene3D G3DSA:3.30.420.40 1 247 1.9E-87 T 28-03-2018 CO689_RS11980 1e7463b8db906613cca04c1bc34c574a 499 SUPERFAMILY SSF53067 254 492 6.48E-86 T 28-03-2018 CO689_RS11980 1e7463b8db906613cca04c1bc34c574a 499 TIGRFAM TIGR01311 glycerol_kin: glycerol kinase 4 493 7.2E-229 T 28-03-2018 IPR005999 Glycerol kinase GO:0004370|GO:0006072 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|Reactome: R-HSA-75109 CO689_RS11980 1e7463b8db906613cca04c1bc34c574a 499 Gene3D G3DSA:3.30.420.40 248 499 3.5E-77 T 28-03-2018 CO689_RS11980 1e7463b8db906613cca04c1bc34c574a 499 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 261 449 2.8E-61 T 28-03-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 CO689_RS11980 1e7463b8db906613cca04c1bc34c574a 499 SUPERFAMILY SSF53067 4 254 4.65E-95 T 28-03-2018 CO689_RS11980 1e7463b8db906613cca04c1bc34c574a 499 PIRSF PIRSF000538 2 497 1.6E-180 T 28-03-2018 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 CO689_RS11980 1e7463b8db906613cca04c1bc34c574a 499 ProSitePatterns PS00933 FGGY family of carbohydrate kinases signature 1. 134 146 - T 28-03-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 CO689_RS11980 1e7463b8db906613cca04c1bc34c574a 499 ProSitePatterns PS00445 FGGY family of carbohydrate kinases signature 2. 361 381 - T 28-03-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 CO689_RS08525 302ab7bfc335c9ea86b26b6730712b9e 268 Pfam PF00005 ABC transporter 21 168 3.5E-35 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CO689_RS08525 302ab7bfc335c9ea86b26b6730712b9e 268 SMART SM00382 29 218 1.1E-18 T 28-03-2018 IPR003593 AAA+ ATPase domain CO689_RS08525 302ab7bfc335c9ea86b26b6730712b9e 268 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CO689_RS08525 302ab7bfc335c9ea86b26b6730712b9e 268 SUPERFAMILY SSF52540 5 231 7.14E-63 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CO689_RS08525 302ab7bfc335c9ea86b26b6730712b9e 268 Gene3D G3DSA:3.40.50.300 2 244 1.4E-61 T 28-03-2018 CO689_RS02635 1142e35fd0e4dc1743a7379b61fd76f2 458 SUPERFAMILY SSF52540 326 440 7.68E-6 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CO689_RS02635 1142e35fd0e4dc1743a7379b61fd76f2 458 SUPERFAMILY SSF88697 6 133 1.16E-12 T 28-03-2018 IPR015947 PUA-like domain CO689_RS02635 1142e35fd0e4dc1743a7379b61fd76f2 458 Gene3D G3DSA:3.10.590.10 4 141 2.3E-10 T 28-03-2018 CO689_RS02635 1142e35fd0e4dc1743a7379b61fd76f2 458 Gene3D G3DSA:3.10.590.10 142 289 3.7E-16 T 28-03-2018 CO689_RS02635 1142e35fd0e4dc1743a7379b61fd76f2 458 SUPERFAMILY SSF88697 141 278 7.87E-20 T 28-03-2018 IPR015947 PUA-like domain CO689_RS02635 1142e35fd0e4dc1743a7379b61fd76f2 458 Pfam PF01878 EVE domain 163 270 2.4E-7 T 28-03-2018 IPR002740 EVE domain CO689_RS06145 b465c6e3e0c5595863f30c32a6c5a4fd 646 SUPERFAMILY SSF63520 287 385 2.35E-22 T 28-03-2018 IPR011608 PRD domain GO:0006355 CO689_RS06145 b465c6e3e0c5595863f30c32a6c5a4fd 646 SUPERFAMILY SSF46785 2 46 3.93E-6 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS06145 b465c6e3e0c5595863f30c32a6c5a4fd 646 SUPERFAMILY SSF55804 497 640 4.97E-26 T 28-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 CO689_RS06145 b465c6e3e0c5595863f30c32a6c5a4fd 646 SUPERFAMILY SSF52794 394 476 2.49E-13 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 CO689_RS06145 b465c6e3e0c5595863f30c32a6c5a4fd 646 SUPERFAMILY SSF46785 83 128 2.25E-7 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS06145 b465c6e3e0c5595863f30c32a6c5a4fd 646 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 500 640 9.6E-25 T 28-03-2018 IPR002178 PTS EIIA type-2 domain CO689_RS06145 b465c6e3e0c5595863f30c32a6c5a4fd 646 Gene3D G3DSA:3.40.930.10 495 642 3.0E-23 T 28-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 CO689_RS06145 b465c6e3e0c5595863f30c32a6c5a4fd 646 Gene3D G3DSA:1.10.1790.10 282 388 1.3E-22 T 28-03-2018 IPR011608 PRD domain GO:0006355 CO689_RS06145 b465c6e3e0c5595863f30c32a6c5a4fd 646 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 397 463 1.7E-5 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 CO689_RS06145 b465c6e3e0c5595863f30c32a6c5a4fd 646 Pfam PF08279 HTH domain 5 45 2.3E-6 T 28-03-2018 IPR013196 Helix-turn-helix, type 11 CO689_RS06145 b465c6e3e0c5595863f30c32a6c5a4fd 646 Pfam PF08279 HTH domain 88 135 2.5E-8 T 28-03-2018 IPR013196 Helix-turn-helix, type 11 CO689_RS06145 b465c6e3e0c5595863f30c32a6c5a4fd 646 Pfam PF00874 PRD domain 200 274 2.4E-13 T 28-03-2018 IPR011608 PRD domain GO:0006355 CO689_RS06145 b465c6e3e0c5595863f30c32a6c5a4fd 646 Pfam PF00874 PRD domain 295 383 1.4E-20 T 28-03-2018 IPR011608 PRD domain GO:0006355 CO689_RS06145 b465c6e3e0c5595863f30c32a6c5a4fd 646 SUPERFAMILY SSF63520 180 275 1.44E-14 T 28-03-2018 IPR011608 PRD domain GO:0006355 CO689_RS06145 b465c6e3e0c5595863f30c32a6c5a4fd 646 Gene3D G3DSA:3.40.50.2300 393 483 4.0E-22 T 28-03-2018 CO689_RS06145 b465c6e3e0c5595863f30c32a6c5a4fd 646 Gene3D G3DSA:1.10.1790.10 173 278 5.5E-15 T 28-03-2018 IPR011608 PRD domain GO:0006355 CO689_RS06145 b465c6e3e0c5595863f30c32a6c5a4fd 646 Gene3D G3DSA:1.10.10.10 81 150 4.1E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS06145 b465c6e3e0c5595863f30c32a6c5a4fd 646 Gene3D G3DSA:1.10.10.10 2 68 7.5E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS06735 20e36a8768e11a331ded426b4d500cf8 113 Gene3D G3DSA:1.10.10.10 1 110 7.1E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS06735 20e36a8768e11a331ded426b4d500cf8 113 SMART SM00418 35 113 4.9E-17 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CO689_RS06735 20e36a8768e11a331ded426b4d500cf8 113 SUPERFAMILY SSF46785 16 104 1.67E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS06735 20e36a8768e11a331ded426b4d500cf8 113 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 69 84 4.4E-14 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CO689_RS06735 20e36a8768e11a331ded426b4d500cf8 113 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 36 51 4.4E-14 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CO689_RS06735 20e36a8768e11a331ded426b4d500cf8 113 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 84 99 4.4E-14 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CO689_RS06735 20e36a8768e11a331ded426b4d500cf8 113 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 56 67 4.4E-14 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CO689_RS06735 20e36a8768e11a331ded426b4d500cf8 113 Pfam PF01022 Bacterial regulatory protein, arsR family 41 84 7.7E-12 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CO689_RS06735 20e36a8768e11a331ded426b4d500cf8 113 ProSitePatterns PS00846 Bacterial regulatory proteins, arsR family signature. 58 76 - T 28-03-2018 IPR018334 ArsR-type transcription regulator, HTH motif GO:0003700|GO:0005622|GO:0006355 CO689_RS01030 1deac1f31ede89b4f34e5961b25baca4 212 SUPERFAMILY SSF53335 33 207 1.64E-29 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CO689_RS01030 1deac1f31ede89b4f34e5961b25baca4 212 Gene3D G3DSA:3.40.50.150 1 210 9.6E-29 T 28-03-2018 CO689_RS01030 1deac1f31ede89b4f34e5961b25baca4 212 TIGRFAM TIGR00091 TIGR00091: tRNA (guanine-N(7)-)-methyltransferase 31 208 8.6E-54 T 28-03-2018 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 Reactome: R-HSA-6782315 CO689_RS01030 1deac1f31ede89b4f34e5961b25baca4 212 Pfam PF02390 Putative methyltransferase 38 206 1.3E-47 T 28-03-2018 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 Reactome: R-HSA-6782315 CO689_RS01030 1deac1f31ede89b4f34e5961b25baca4 212 Hamap MF_01057 tRNA (guanine-N(7)-)-methyltransferase [trmB]. 1 211 29.863 T 28-03-2018 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 Reactome: R-HSA-6782315 CO689_RS10365 d05c44dff233acd6f2efc99b42c37f35 234 TIGRFAM TIGR00007 TIGR00007: 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase 4 229 1.1E-72 T 28-03-2018 IPR006063 Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase HisA GO:0000105|GO:0003949 KEGG: 00340+5.3.1.16 CO689_RS10365 d05c44dff233acd6f2efc99b42c37f35 234 Pfam PF00977 Histidine biosynthesis protein 4 226 1.0E-64 T 28-03-2018 IPR006062 Histidine biosynthesis GO:0000105 CO689_RS10365 d05c44dff233acd6f2efc99b42c37f35 234 Gene3D G3DSA:3.20.20.70 2 233 3.7E-43 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CO689_RS10365 d05c44dff233acd6f2efc99b42c37f35 234 SUPERFAMILY SSF51366 1 227 1.26E-53 T 28-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 CO689_RS10365 d05c44dff233acd6f2efc99b42c37f35 234 Hamap MF_01014 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase [hisA]. 3 232 27.315 T 28-03-2018 IPR023016 Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase GO:0000105|GO:0003949 KEGG: 00340+5.3.1.16 CO689_RS00310 ec6446eb2e4e78f895196e8a46e2d787 547 PIRSF PIRSF000350 2 547 8.4E-255 T 28-03-2018 CO689_RS00310 ec6446eb2e4e78f895196e8a46e2d787 547 SUPERFAMILY SSF51905 85 446 8.87E-54 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CO689_RS00310 ec6446eb2e4e78f895196e8a46e2d787 547 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 86 403 1.5E-70 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CO689_RS00310 ec6446eb2e4e78f895196e8a46e2d787 547 Gene3D G3DSA:3.30.390.30 422 547 5.6E-37 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CO689_RS00310 ec6446eb2e4e78f895196e8a46e2d787 547 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 423 531 2.2E-31 T 28-03-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 CO689_RS00310 ec6446eb2e4e78f895196e8a46e2d787 547 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 120 130 - T 28-03-2018 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 CO689_RS00310 ec6446eb2e4e78f895196e8a46e2d787 547 Gene3D G3DSA:3.30.70.100 1 69 1.8E-11 T 28-03-2018 CO689_RS00310 ec6446eb2e4e78f895196e8a46e2d787 547 SUPERFAMILY SSF55424 419 545 4.3E-35 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CO689_RS00310 ec6446eb2e4e78f895196e8a46e2d787 547 SUPERFAMILY SSF55008 2 66 6.02E-8 T 28-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 CO689_RS00310 ec6446eb2e4e78f895196e8a46e2d787 547 TIGRFAM TIGR02053 MerA: mercury(II) reductase 86 547 6.8E-197 T 28-03-2018 IPR021179 Mercury(II) reductase GO:0016152|GO:0016491|GO:0045340|GO:0050660|GO:0050661|GO:0050787|GO:0055114 CO689_RS00310 ec6446eb2e4e78f895196e8a46e2d787 547 ProSitePatterns PS01047 Heavy-metal-associated domain. 9 37 - T 28-03-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 CO689_RS00310 ec6446eb2e4e78f895196e8a46e2d787 547 PRINTS PR00945 Mercuric reductase class II signature 217 234 1.2E-70 T 28-03-2018 CO689_RS00310 ec6446eb2e4e78f895196e8a46e2d787 547 PRINTS PR00945 Mercuric reductase class II signature 132 151 1.2E-70 T 28-03-2018 CO689_RS00310 ec6446eb2e4e78f895196e8a46e2d787 547 PRINTS PR00945 Mercuric reductase class II signature 97 115 1.2E-70 T 28-03-2018 CO689_RS00310 ec6446eb2e4e78f895196e8a46e2d787 547 PRINTS PR00945 Mercuric reductase class II signature 455 475 1.2E-70 T 28-03-2018 CO689_RS00310 ec6446eb2e4e78f895196e8a46e2d787 547 PRINTS PR00945 Mercuric reductase class II signature 272 287 1.2E-70 T 28-03-2018 CO689_RS00310 ec6446eb2e4e78f895196e8a46e2d787 547 PRINTS PR00945 Mercuric reductase class II signature 520 539 1.2E-70 T 28-03-2018 CO689_RS00310 ec6446eb2e4e78f895196e8a46e2d787 547 PRINTS PR00945 Mercuric reductase class II signature 252 269 1.2E-70 T 28-03-2018 CO689_RS00310 ec6446eb2e4e78f895196e8a46e2d787 547 PRINTS PR00945 Mercuric reductase class II signature 16 26 1.2E-70 T 28-03-2018 CO689_RS00310 ec6446eb2e4e78f895196e8a46e2d787 547 Gene3D G3DSA:3.50.50.60 83 236 2.2E-21 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CO689_RS00310 ec6446eb2e4e78f895196e8a46e2d787 547 Gene3D G3DSA:3.40.50.720 237 411 4.6E-33 T 28-03-2018 CO689_RS06520 3aba91ab124594487f5f8f4dd65f0554 423 Gene3D G3DSA:3.20.20.140 64 363 4.3E-37 T 28-03-2018 CO689_RS06520 3aba91ab124594487f5f8f4dd65f0554 423 ProSitePatterns PS01137 TatD deoxyribonuclease family signature 1. 51 59 - T 28-03-2018 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 CO689_RS06520 3aba91ab124594487f5f8f4dd65f0554 423 SUPERFAMILY SSF51556 50 375 8.32E-82 T 28-03-2018 IPR032466 Metal-dependent hydrolase CO689_RS06520 3aba91ab124594487f5f8f4dd65f0554 423 SUPERFAMILY SSF51338 2 63 5.59E-11 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CO689_RS06520 3aba91ab124594487f5f8f4dd65f0554 423 Gene3D G3DSA:2.30.40.10 5 63 5.9E-11 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CO689_RS06520 3aba91ab124594487f5f8f4dd65f0554 423 Pfam PF07969 Amidohydrolase family 89 403 4.2E-26 T 28-03-2018 IPR013108 Amidohydrolase 3 CO689_RS12840 0161bdd346db84773333b4abbfbea70f 458 SMART SM00487 11 203 8.3E-31 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CO689_RS12840 0161bdd346db84773333b4abbfbea70f 458 SMART SM00490 238 319 3.1E-28 T 28-03-2018 IPR001650 Helicase, C-terminal CO689_RS12840 0161bdd346db84773333b4abbfbea70f 458 Gene3D G3DSA:3.40.50.300 1 195 1.3E-32 T 28-03-2018 CO689_RS12840 0161bdd346db84773333b4abbfbea70f 458 Pfam PF00270 DEAD/DEAH box helicase 18 173 2.9E-18 T 28-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CO689_RS12840 0161bdd346db84773333b4abbfbea70f 458 SUPERFAMILY SSF52540 54 337 6.0E-58 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CO689_RS12840 0161bdd346db84773333b4abbfbea70f 458 Pfam PF00271 Helicase conserved C-terminal domain 213 318 1.2E-20 T 28-03-2018 IPR001650 Helicase, C-terminal CO689_RS12840 0161bdd346db84773333b4abbfbea70f 458 TIGRFAM TIGR00614 recQ_fam: ATP-dependent DNA helicase, RecQ family 5 341 1.0E-98 T 28-03-2018 IPR004589 DNA helicase, ATP-dependent, RecQ type GO:0006310|GO:0008026 CO689_RS12840 0161bdd346db84773333b4abbfbea70f 458 Pfam PF16124 RecQ zinc-binding 385 428 2.9E-8 T 28-03-2018 IPR032284 ATP-dependent DNA helicase RecQ, zinc-binding domain CO689_RS12840 0161bdd346db84773333b4abbfbea70f 458 ProSitePatterns PS00690 DEAH-box subfamily ATP-dependent helicases signature. 129 138 - T 28-03-2018 IPR002464 DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site CO689_RS12840 0161bdd346db84773333b4abbfbea70f 458 Gene3D G3DSA:1.10.10.10 356 458 1.5E-8 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS12840 0161bdd346db84773333b4abbfbea70f 458 Gene3D G3DSA:3.40.50.300 198 355 2.0E-35 T 28-03-2018 CO689_RS01870 c24491162c51f068bb10dfbad1fd4b29 458 Gene3D G3DSA:3.40.605.10 1 228 8.3E-66 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CO689_RS01870 c24491162c51f068bb10dfbad1fd4b29 458 Gene3D G3DSA:3.40.309.10 229 410 3.4E-71 T 28-03-2018 CO689_RS01870 c24491162c51f068bb10dfbad1fd4b29 458 PIRSF PIRSF036492 1 458 4.6E-186 T 28-03-2018 IPR012394 Aldehyde dehydrogenase NAD(P)-dependent GO:0004030|GO:0006081|GO:0055114 CO689_RS01870 c24491162c51f068bb10dfbad1fd4b29 458 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 237 248 - T 28-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 CO689_RS01870 c24491162c51f068bb10dfbad1fd4b29 458 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 209 216 - T 28-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 CO689_RS01870 c24491162c51f068bb10dfbad1fd4b29 458 Pfam PF00171 Aldehyde dehydrogenase family 7 429 6.1E-96 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CO689_RS01870 c24491162c51f068bb10dfbad1fd4b29 458 SUPERFAMILY SSF53720 5 441 2.62E-123 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CO689_RS09430 7b822a155640111308823e1c9c3bcb5c 171 Gene3D G3DSA:3.40.630.30 1 167 2.3E-15 T 28-03-2018 CO689_RS09430 7b822a155640111308823e1c9c3bcb5c 171 SUPERFAMILY SSF55729 1 162 5.93E-17 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CO689_RS09430 7b822a155640111308823e1c9c3bcb5c 171 Pfam PF13420 Acetyltransferase (GNAT) domain 4 159 6.3E-36 T 28-03-2018 CO689_RS03300 62e22ce6af5b924adc7d775af3e70666 419 SMART SM00852 186 324 2.2E-37 T 28-03-2018 IPR001453 MoaB/Mog domain CO689_RS03300 62e22ce6af5b924adc7d775af3e70666 419 Pfam PF03454 MoeA C-terminal region (domain IV) 337 407 2.0E-16 T 28-03-2018 IPR005111 MoeA, C-terminal, domain IV GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 CO689_RS03300 62e22ce6af5b924adc7d775af3e70666 419 SUPERFAMILY SSF63882 9 181 6.67E-52 T 28-03-2018 IPR005110 MoeA, N-terminal and linker domain GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 CO689_RS03300 62e22ce6af5b924adc7d775af3e70666 419 Pfam PF03453 MoeA N-terminal region (domain I and II) 10 173 6.7E-41 T 28-03-2018 IPR005110 MoeA, N-terminal and linker domain GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 CO689_RS03300 62e22ce6af5b924adc7d775af3e70666 419 SUPERFAMILY SSF63867 333 407 5.23E-16 T 28-03-2018 IPR005111 MoeA, C-terminal, domain IV GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 CO689_RS03300 62e22ce6af5b924adc7d775af3e70666 419 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 183 320 2.5E-31 T 28-03-2018 IPR001453 MoaB/Mog domain CO689_RS03300 62e22ce6af5b924adc7d775af3e70666 419 Gene3D G3DSA:3.90.105.10 26 62 1.6E-5 T 28-03-2018 CO689_RS03300 62e22ce6af5b924adc7d775af3e70666 419 SUPERFAMILY SSF53218 183 329 9.29E-40 T 28-03-2018 IPR001453 MoaB/Mog domain CO689_RS03300 62e22ce6af5b924adc7d775af3e70666 419 Pfam PF00994 Probable molybdopterin binding domain 187 322 3.5E-26 T 28-03-2018 IPR001453 MoaB/Mog domain CO689_RS03300 62e22ce6af5b924adc7d775af3e70666 419 Gene3D G3DSA:2.170.190.11 63 147 7.3E-26 T 28-03-2018 CO689_RS03300 62e22ce6af5b924adc7d775af3e70666 419 Gene3D G3DSA:3.40.980.10 157 331 2.3E-51 T 28-03-2018 IPR001453 MoaB/Mog domain CO689_RS03300 62e22ce6af5b924adc7d775af3e70666 419 Gene3D G3DSA:2.40.340.10 334 410 4.7E-13 T 28-03-2018 IPR005111 MoeA, C-terminal, domain IV GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 CO689_RS12040 91369452b126b6647f477d5903faab0e 446 Pfam PF03951 Glutamine synthetase, beta-Grasp domain 19 99 6.3E-32 T 28-03-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CO689_RS12040 91369452b126b6647f477d5903faab0e 446 SUPERFAMILY SSF54368 7 106 5.1E-34 T 28-03-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CO689_RS12040 91369452b126b6647f477d5903faab0e 446 ProSitePatterns PS00181 Glutamine synthetase putative ATP-binding region signature. 236 251 - T 28-03-2018 IPR027303 Glutamine synthetase, glycine-rich site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 CO689_RS12040 91369452b126b6647f477d5903faab0e 446 Gene3D G3DSA:3.10.20.70 4 106 1.9E-36 T 28-03-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CO689_RS12040 91369452b126b6647f477d5903faab0e 446 ProSitePatterns PS00180 Glutamine synthetase signature 1. 54 72 - T 28-03-2018 IPR027302 Glutamine synthetase, N-terminal conserved site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 CO689_RS12040 91369452b126b6647f477d5903faab0e 446 Gene3D G3DSA:3.30.590.10 107 446 6.4E-124 T 28-03-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 CO689_RS12040 91369452b126b6647f477d5903faab0e 446 SUPERFAMILY SSF55931 108 444 1.57E-124 T 28-03-2018 CO689_RS12040 91369452b126b6647f477d5903faab0e 446 Pfam PF00120 Glutamine synthetase, catalytic domain 108 442 4.3E-135 T 28-03-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CO689_RS12040 91369452b126b6647f477d5903faab0e 446 SMART SM01230 107 356 3.8E-136 T 28-03-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CO689_RS12040 91369452b126b6647f477d5903faab0e 446 TIGRFAM TIGR00653 GlnA: glutamine synthetase, type I 11 443 3.0E-171 T 28-03-2018 IPR004809 Glutamine synthetase type I GO:0004356|GO:0005737|GO:0009399 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CO689_RS07470 7a303c6f165c6cc5e437266c13152775 1496 Gene3D G3DSA:3.20.20.70 439 769 7.7E-88 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CO689_RS07470 7a303c6f165c6cc5e437266c13152775 1496 Gene3D G3DSA:2.160.20.60 1204 1475 1.0E-94 T 28-03-2018 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0008152|GO:0016491|GO:0055114 CO689_RS07470 7a303c6f165c6cc5e437266c13152775 1496 Pfam PF01493 GXGXG motif 1228 1412 1.9E-70 T 28-03-2018 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0008152|GO:0016491|GO:0055114 CO689_RS07470 7a303c6f165c6cc5e437266c13152775 1496 Pfam PF04898 Glutamate synthase central domain 456 731 3.3E-99 T 28-03-2018 IPR006982 Glutamate synthase, central-N GO:0006807|GO:0015930|GO:0055114 CO689_RS07470 7a303c6f165c6cc5e437266c13152775 1496 Pfam PF00310 Glutamine amidotransferases class-II 19 429 9.0E-154 T 28-03-2018 IPR017932 Glutamine amidotransferase type 2 domain CO689_RS07470 7a303c6f165c6cc5e437266c13152775 1496 SUPERFAMILY SSF51395 452 1187 1.71E-236 T 28-03-2018 CO689_RS07470 7a303c6f165c6cc5e437266c13152775 1496 SUPERFAMILY SSF56235 19 432 9.01E-126 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CO689_RS07470 7a303c6f165c6cc5e437266c13152775 1496 Gene3D G3DSA:3.20.20.70 770 1203 4.0E-153 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CO689_RS07470 7a303c6f165c6cc5e437266c13152775 1496 SUPERFAMILY SSF69336 1202 1459 1.31E-81 T 28-03-2018 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0008152|GO:0016491|GO:0055114 CO689_RS07470 7a303c6f165c6cc5e437266c13152775 1496 Gene3D G3DSA:3.60.20.10 19 438 1.3E-132 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CO689_RS07470 7a303c6f165c6cc5e437266c13152775 1496 Pfam PF01645 Conserved region in glutamate synthase 785 1150 9.5E-153 T 28-03-2018 IPR002932 Glutamate synthase domain GO:0006537|GO:0015930|GO:0016638|GO:0055114 CO689_RS10100 1487d550112889076dbabaf38fa27430 1156 Pfam PF13361 UvrD-like helicase C-terminal domain 269 657 4.1E-13 T 28-03-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 CO689_RS10100 1487d550112889076dbabaf38fa27430 1156 Gene3D G3DSA:3.90.320.10 691 1002 4.8E-12 T 28-03-2018 IPR011604 Exonuclease, phage-type/RecB, C-terminal GO:0003677|GO:0004518 CO689_RS10100 1487d550112889076dbabaf38fa27430 1156 SUPERFAMILY SSF52540 8 278 7.53E-7 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CO689_RS10100 1487d550112889076dbabaf38fa27430 1156 TIGRFAM TIGR02773 addB_Gpos: helicase-exonuclease AddAB, AddB subunit 4 1154 0.0 T 28-03-2018 IPR014140 DNA helicase subunit AddB GO:0000724|GO:0016788 CO689_RS10100 1487d550112889076dbabaf38fa27430 1156 Hamap MF_01452 ATP-dependent helicase/deoxyribonuclease subunit B [addB]. 2 1153 53.992 T 28-03-2018 IPR014140 DNA helicase subunit AddB GO:0000724|GO:0016788 CO689_RS10100 1487d550112889076dbabaf38fa27430 1156 Gene3D G3DSA:3.40.50.300 260 687 9.5E-34 T 28-03-2018 CO689_RS10100 1487d550112889076dbabaf38fa27430 1156 SUPERFAMILY SSF52540 293 684 4.86E-54 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CO689_RS10100 1487d550112889076dbabaf38fa27430 1156 Pfam PF12705 PD-(D/E)XK nuclease superfamily 774 1122 1.7E-53 T 28-03-2018 CO689_RS10100 1487d550112889076dbabaf38fa27430 1156 Gene3D G3DSA:3.40.50.300 117 259 1.2E-27 T 28-03-2018 CO689_RS10100 1487d550112889076dbabaf38fa27430 1156 Gene3D G3DSA:3.40.50.300 3 116 1.5E-24 T 28-03-2018 CO689_RS06360 3b5e69d760d0caee6e6b6dc8f14339f9 268 SUPERFAMILY SSF56300 1 119 3.04E-30 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CO689_RS06360 3b5e69d760d0caee6e6b6dc8f14339f9 268 SUPERFAMILY SSF56300 151 257 3.04E-30 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CO689_RS06360 3b5e69d760d0caee6e6b6dc8f14339f9 268 TIGRFAM TIGR03729 acc_ester: putative phosphoesterase 2 246 5.9E-67 T 28-03-2018 IPR022302 Phosphoesterase, putative CO689_RS06360 3b5e69d760d0caee6e6b6dc8f14339f9 268 Gene3D G3DSA:3.60.21.10 1 265 6.9E-27 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CO689_RS06360 3b5e69d760d0caee6e6b6dc8f14339f9 268 Pfam PF00149 Calcineurin-like phosphoesterase 1 227 1.7E-15 T 28-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 CO689_RS02615 5df89602632b436e003f2faa9fa3238d 235 TIGRFAM TIGR00107 deoD: purine nucleoside phosphorylase 7 234 2.2E-91 T 28-03-2018 IPR004402 Purine nucleoside phosphorylase DeoD-type GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1 CO689_RS02615 5df89602632b436e003f2faa9fa3238d 235 Hamap MF_01627 Purine nucleoside phosphorylase DeoD-type [deoD]. 4 235 41.436 T 28-03-2018 IPR004402 Purine nucleoside phosphorylase DeoD-type GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1 CO689_RS02615 5df89602632b436e003f2faa9fa3238d 235 SUPERFAMILY SSF53167 5 235 9.3E-89 T 28-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 CO689_RS02615 5df89602632b436e003f2faa9fa3238d 235 ProSitePatterns PS01232 Purine and other phosphorylases family 1 signature. 64 79 - T 28-03-2018 IPR018016 Nucleoside phosphorylase, conserved site GO:0016763 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|Reactome: R-HSA-73614|Reactome: R-HSA-73621 CO689_RS02615 5df89602632b436e003f2faa9fa3238d 235 Pfam PF01048 Phosphorylase superfamily 18 224 1.6E-35 T 28-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 CO689_RS02615 5df89602632b436e003f2faa9fa3238d 235 Gene3D G3DSA:3.40.50.1580 12 235 3.8E-51 T 28-03-2018 CO689_RS02470 9313cbf50466a8dfa1569e9937edefff 70 SUPERFAMILY SSF81333 3 69 8.24E-20 T 28-03-2018 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 CO689_RS02470 9313cbf50466a8dfa1569e9937edefff 70 PRINTS PR00124 ATP synthase C subunit signature 43 68 1.6E-20 T 28-03-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CO689_RS02470 9313cbf50466a8dfa1569e9937edefff 70 PRINTS PR00124 ATP synthase C subunit signature 5 24 1.6E-20 T 28-03-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CO689_RS02470 9313cbf50466a8dfa1569e9937edefff 70 PRINTS PR00124 ATP synthase C subunit signature 26 41 1.6E-20 T 28-03-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CO689_RS02470 9313cbf50466a8dfa1569e9937edefff 70 TIGRFAM TIGR01260 ATP_synt_c: ATP synthase F0, C subunit 14 69 5.8E-22 T 28-03-2018 IPR005953 ATP synthase, F0 complex, subunit C, bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 CO689_RS02470 9313cbf50466a8dfa1569e9937edefff 70 ProSitePatterns PS00605 ATP synthase c subunit signature. 33 54 - T 28-03-2018 IPR020537 ATP synthase, F0 complex, subunit C, DCCD-binding site Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CO689_RS02470 9313cbf50466a8dfa1569e9937edefff 70 Pfam PF00137 ATP synthase subunit C 4 66 5.3E-15 T 28-03-2018 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 CO689_RS02470 9313cbf50466a8dfa1569e9937edefff 70 Hamap MF_01396 ATP synthase subunit c [atpH]. 3 68 15.799 T 28-03-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CO689_RS02470 9313cbf50466a8dfa1569e9937edefff 70 Gene3D G3DSA:1.20.20.10 1 70 3.2E-22 T 28-03-2018 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 CO689_RS05910 b2e941eb24e03a261976a89b520a6563 359 PRINTS PR00069 Aldo-keto reductase signature 111 129 4.3E-7 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CO689_RS05910 b2e941eb24e03a261976a89b520a6563 359 PRINTS PR00069 Aldo-keto reductase signature 142 159 4.3E-7 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CO689_RS05910 b2e941eb24e03a261976a89b520a6563 359 PRINTS PR00069 Aldo-keto reductase signature 47 71 4.3E-7 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CO689_RS05910 b2e941eb24e03a261976a89b520a6563 359 Gene3D G3DSA:3.20.20.100 1 343 8.8E-86 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CO689_RS05910 b2e941eb24e03a261976a89b520a6563 359 SUPERFAMILY SSF51430 1 323 2.36E-90 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CO689_RS05910 b2e941eb24e03a261976a89b520a6563 359 Pfam PF00248 Aldo/keto reductase family 26 316 2.3E-69 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CO689_RS11275 efe1f41bb7c859cb7344c73431fe02d0 915 SUPERFAMILY SSF50677 201 394 3.66E-62 T 28-03-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 CO689_RS11275 efe1f41bb7c859cb7344c73431fe02d0 915 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 27 634 6.9E-229 T 28-03-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 CO689_RS11275 efe1f41bb7c859cb7344c73431fe02d0 915 TIGRFAM TIGR00392 ileS: isoleucine--tRNA ligase 14 830 1.1E-300 T 28-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 CO689_RS11275 efe1f41bb7c859cb7344c73431fe02d0 915 Pfam PF06827 Zinc finger found in FPG and IleRS 882 910 4.6E-11 T 28-03-2018 IPR010663 Zinc finger, FPG/IleRS-type Reactome: R-HSA-379726 CO689_RS11275 efe1f41bb7c859cb7344c73431fe02d0 915 Gene3D G3DSA:3.30.2320.20 793 880 6.6E-23 T 28-03-2018 CO689_RS11275 efe1f41bb7c859cb7344c73431fe02d0 915 Hamap MF_02002 Isoleucine--tRNA ligase [ileS]. 1 913 20.875 T 28-03-2018 IPR023585 Isoleucine-tRNA ligase, type 1 GO:0004822 KEGG: 00970+6.1.1.5|Reactome: R-HSA-379726 CO689_RS11275 efe1f41bb7c859cb7344c73431fe02d0 915 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 554 563 1.5E-32 T 28-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 CO689_RS11275 efe1f41bb7c859cb7344c73431fe02d0 915 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 228 251 1.5E-32 T 28-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 CO689_RS11275 efe1f41bb7c859cb7344c73431fe02d0 915 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 50 61 1.5E-32 T 28-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 CO689_RS11275 efe1f41bb7c859cb7344c73431fe02d0 915 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 520 533 1.5E-32 T 28-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 CO689_RS11275 efe1f41bb7c859cb7344c73431fe02d0 915 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 392 407 1.5E-32 T 28-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 CO689_RS11275 efe1f41bb7c859cb7344c73431fe02d0 915 Gene3D G3DSA:3.40.50.620 41 118 2.5E-29 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CO689_RS11275 efe1f41bb7c859cb7344c73431fe02d0 915 SUPERFAMILY SSF52374 1 200 6.98E-153 T 28-03-2018 CO689_RS11275 efe1f41bb7c859cb7344c73431fe02d0 915 SUPERFAMILY SSF52374 394 641 6.98E-153 T 28-03-2018 CO689_RS11275 efe1f41bb7c859cb7344c73431fe02d0 915 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 57 68 - T 28-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 CO689_RS11275 efe1f41bb7c859cb7344c73431fe02d0 915 SUPERFAMILY SSF47323 645 913 1.78E-79 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CO689_RS11275 efe1f41bb7c859cb7344c73431fe02d0 915 Pfam PF08264 Anticodon-binding domain of tRNA 678 831 9.0E-29 T 28-03-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 CO689_RS11275 efe1f41bb7c859cb7344c73431fe02d0 915 Gene3D G3DSA:3.90.740.10 203 490 1.5E-95 T 28-03-2018 CO689_RS11275 efe1f41bb7c859cb7344c73431fe02d0 915 Gene3D G3DSA:1.10.730.10 571 792 3.7E-49 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CO689_RS00195 c90138401b85e9184c4705d18b2c3716 399 TIGRFAM TIGR04538 P450_cycloAA_1: cytochrome P450, cyclodipeptide synthase-associated 7 399 8.7E-202 T 28-03-2018 IPR030904 Cytochrome P450, CypX GO:0005506|GO:0016491|GO:0020037|GO:0046148|GO:0055114 CO689_RS00195 c90138401b85e9184c4705d18b2c3716 399 SUPERFAMILY SSF48264 11 396 5.89E-74 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CO689_RS00195 c90138401b85e9184c4705d18b2c3716 399 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 343 352 - T 28-03-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 CO689_RS00195 c90138401b85e9184c4705d18b2c3716 399 PRINTS PR00359 B-class P450 signature 350 361 2.0E-29 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CO689_RS00195 c90138401b85e9184c4705d18b2c3716 399 PRINTS PR00359 B-class P450 signature 341 350 2.0E-29 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CO689_RS00195 c90138401b85e9184c4705d18b2c3716 399 PRINTS PR00359 B-class P450 signature 311 326 2.0E-29 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CO689_RS00195 c90138401b85e9184c4705d18b2c3716 399 PRINTS PR00359 B-class P450 signature 141 156 2.0E-29 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CO689_RS00195 c90138401b85e9184c4705d18b2c3716 399 PRINTS PR00359 B-class P450 signature 266 277 2.0E-29 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CO689_RS00195 c90138401b85e9184c4705d18b2c3716 399 PRINTS PR00359 B-class P450 signature 283 310 2.0E-29 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CO689_RS00195 c90138401b85e9184c4705d18b2c3716 399 PRINTS PR00359 B-class P450 signature 185 207 2.0E-29 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CO689_RS00195 c90138401b85e9184c4705d18b2c3716 399 Gene3D G3DSA:1.10.630.10 3 399 3.1E-66 T 28-03-2018 CO689_RS00195 c90138401b85e9184c4705d18b2c3716 399 Pfam PF00067 Cytochrome P450 37 372 1.1E-36 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CO689_RS13560 0d6f56eaf49ab28c882db89cded8b579 430 TIGRFAM TIGR02729 Obg_CgtA: Obg family GTPase CgtA 2 328 3.0E-140 T 28-03-2018 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 CO689_RS13560 0d6f56eaf49ab28c882db89cded8b579 430 SUPERFAMILY SSF82051 1 157 1.27E-54 T 28-03-2018 IPR006169 GTP1/OBG domain CO689_RS13560 0d6f56eaf49ab28c882db89cded8b579 430 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 160 322 4.1E-14 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 CO689_RS13560 0d6f56eaf49ab28c882db89cded8b579 430 PIRSF PIRSF002401 1 378 5.5E-141 T 28-03-2018 IPR035101 GTP-binding protein, Obg-type CO689_RS13560 0d6f56eaf49ab28c882db89cded8b579 430 SUPERFAMILY SSF102741 358 430 2.62E-23 T 28-03-2018 IPR015349 GTP-binding protein OBG, C-terminal GO:0000166 CO689_RS13560 0d6f56eaf49ab28c882db89cded8b579 430 Pfam PF01018 GTP1/OBG 3 157 1.7E-58 T 28-03-2018 IPR006169 GTP1/OBG domain CO689_RS13560 0d6f56eaf49ab28c882db89cded8b579 430 Hamap MF_01454 GTPase Obg [obg]. 1 329 47.185 T 28-03-2018 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 CO689_RS13560 0d6f56eaf49ab28c882db89cded8b579 430 TIGRFAM TIGR03595 Obg_CgtA_exten: Obg family GTPase CgtA, C-terminal extension 360 429 2.1E-27 T 28-03-2018 IPR015349 GTP-binding protein OBG, C-terminal GO:0000166 CO689_RS13560 0d6f56eaf49ab28c882db89cded8b579 430 Pfam PF09269 Domain of unknown function (DUF1967) 360 428 1.6E-25 T 28-03-2018 IPR015349 GTP-binding protein OBG, C-terminal GO:0000166 CO689_RS13560 0d6f56eaf49ab28c882db89cded8b579 430 SUPERFAMILY SSF52540 160 333 2.84E-54 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CO689_RS13560 0d6f56eaf49ab28c882db89cded8b579 430 ProSitePatterns PS00905 GTP1/OBG family signature. 212 225 - T 28-03-2018 IPR006074 GTP1/OBG, conserved site GO:0005525 CO689_RS13560 0d6f56eaf49ab28c882db89cded8b579 430 Gene3D G3DSA:2.70.210.12 1 155 1.3E-56 T 28-03-2018 IPR006169 GTP1/OBG domain CO689_RS13560 0d6f56eaf49ab28c882db89cded8b579 430 Gene3D G3DSA:3.40.50.300 158 340 8.3E-37 T 28-03-2018 CO689_RS13560 0d6f56eaf49ab28c882db89cded8b579 430 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 227 245 9.3E-35 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CO689_RS13560 0d6f56eaf49ab28c882db89cded8b579 430 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 182 200 9.3E-35 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CO689_RS13560 0d6f56eaf49ab28c882db89cded8b579 430 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 210 225 9.3E-35 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CO689_RS13560 0d6f56eaf49ab28c882db89cded8b579 430 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 161 181 9.3E-35 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CO689_RS13560 0d6f56eaf49ab28c882db89cded8b579 430 Pfam PF01926 50S ribosome-binding GTPase 160 283 8.9E-25 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CO689_RS01640 65f8a3afe5edbca2ec7b74ca795bdaaa 348 SUPERFAMILY SSF55811 219 345 1.08E-20 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CO689_RS01640 65f8a3afe5edbca2ec7b74ca795bdaaa 348 Pfam PF14815 NUDIX domain 235 343 4.1E-22 T 28-03-2018 IPR029119 MutY, C-terminal Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 CO689_RS01640 65f8a3afe5edbca2ec7b74ca795bdaaa 348 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 35 168 4.5E-18 T 28-03-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 CO689_RS01640 65f8a3afe5edbca2ec7b74ca795bdaaa 348 SMART SM00478 39 189 2.7E-36 T 28-03-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 CO689_RS01640 65f8a3afe5edbca2ec7b74ca795bdaaa 348 SMART SM00525 190 210 7.7E-4 T 28-03-2018 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: R-HSA-110357 CO689_RS01640 65f8a3afe5edbca2ec7b74ca795bdaaa 348 Gene3D G3DSA:3.90.79.10 228 348 1.7E-9 T 28-03-2018 CO689_RS01640 65f8a3afe5edbca2ec7b74ca795bdaaa 348 ProSitePatterns PS00764 Endonuclease III iron-sulfur binding region signature. 191 207 - T 28-03-2018 IPR004035 Endonuclease III, iron-sulphur binding site Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 CO689_RS01640 65f8a3afe5edbca2ec7b74ca795bdaaa 348 TIGRFAM TIGR01084 mutY: A/G-specific adenine glycosylase 7 266 2.0E-99 T 28-03-2018 IPR005760 A/G-specific adenine glycosylase MutY GO:0006284|GO:0019104 CO689_RS01640 65f8a3afe5edbca2ec7b74ca795bdaaa 348 SUPERFAMILY SSF48150 7 221 2.51E-68 T 28-03-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 CO689_RS01640 65f8a3afe5edbca2ec7b74ca795bdaaa 348 Gene3D G3DSA:1.10.340.30 21 117 3.5E-28 T 28-03-2018 CO689_RS01640 65f8a3afe5edbca2ec7b74ca795bdaaa 348 Gene3D G3DSA:1.10.1670.10 118 224 2.7E-30 T 28-03-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 CO689_RS04285 9e5179e6cee2f29a39773340e78ebcf7 220 Pfam PF13346 ABC-2 family transporter protein 3 216 3.5E-30 T 28-03-2018 IPR025699 ABC-2 membrane transporter-like CO689_RS10740 cced503bb851041c48ac47ca485adf9f 729 PIRSF PIRSF001587 7 728 1.1E-300 T 28-03-2018 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 CO689_RS10740 cced503bb851041c48ac47ca485adf9f 729 SUPERFAMILY SSF55326 18 202 4.04E-51 T 28-03-2018 IPR016188 PurM-like, N-terminal domain CO689_RS10740 cced503bb851041c48ac47ca485adf9f 729 SUPERFAMILY SSF55326 393 562 2.09E-52 T 28-03-2018 IPR016188 PurM-like, N-terminal domain CO689_RS10740 cced503bb851041c48ac47ca485adf9f 729 Gene3D G3DSA:3.30.1330.10 22 199 6.2E-53 T 28-03-2018 IPR016188 PurM-like, N-terminal domain CO689_RS10740 cced503bb851041c48ac47ca485adf9f 729 SUPERFAMILY SSF56042 204 425 1.15E-51 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain CO689_RS10740 cced503bb851041c48ac47ca485adf9f 729 Gene3D G3DSA:3.90.650.10 567 727 8.7E-22 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain CO689_RS10740 cced503bb851041c48ac47ca485adf9f 729 Gene3D G3DSA:3.90.650.10 201 378 1.8E-24 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain CO689_RS10740 cced503bb851041c48ac47ca485adf9f 729 Gene3D G3DSA:3.30.1330.10 414 562 5.2E-43 T 28-03-2018 IPR016188 PurM-like, N-terminal domain CO689_RS10740 cced503bb851041c48ac47ca485adf9f 729 SUPERFAMILY SSF56042 569 725 1.94E-26 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain CO689_RS10740 cced503bb851041c48ac47ca485adf9f 729 Pfam PF02769 AIR synthase related protein, C-terminal domain 570 699 4.9E-7 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain CO689_RS10740 cced503bb851041c48ac47ca485adf9f 729 Pfam PF02769 AIR synthase related protein, C-terminal domain 207 360 2.9E-31 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain CO689_RS10740 cced503bb851041c48ac47ca485adf9f 729 Hamap MF_00420 Phosphoribosylformylglycinamidine synthase subunit PurL [purL]. 1 729 289.333 T 28-03-2018 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 CO689_RS10740 cced503bb851041c48ac47ca485adf9f 729 TIGRFAM TIGR01736 FGAM_synth_II: phosphoribosylformylglycinamidine synthase II 23 725 2.6E-295 T 28-03-2018 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 CO689_RS10740 cced503bb851041c48ac47ca485adf9f 729 Pfam PF00586 AIR synthase related protein, N-terminal domain 89 194 2.2E-22 T 28-03-2018 IPR016188 PurM-like, N-terminal domain CO689_RS10740 cced503bb851041c48ac47ca485adf9f 729 Pfam PF00586 AIR synthase related protein, N-terminal domain 452 557 1.7E-21 T 28-03-2018 IPR016188 PurM-like, N-terminal domain CO689_RS13285 fcdc4c953e7ff0a6f6967f30c26eeb8f 250 SUPERFAMILY SSF75217 73 247 2.75E-51 T 28-03-2018 IPR029028 Alpha/beta knot methyltransferases CO689_RS13285 fcdc4c953e7ff0a6f6967f30c26eeb8f 250 Pfam PF04452 RNA methyltransferase 18 244 2.7E-72 T 28-03-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CO689_RS13285 fcdc4c953e7ff0a6f6967f30c26eeb8f 250 TIGRFAM TIGR00046 TIGR00046: RNA methyltransferase, RsmE family 6 247 8.0E-62 T 28-03-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CO689_RS13285 fcdc4c953e7ff0a6f6967f30c26eeb8f 250 SUPERFAMILY SSF88697 1 70 1.32E-13 T 28-03-2018 IPR015947 PUA-like domain CO689_RS13285 fcdc4c953e7ff0a6f6967f30c26eeb8f 250 Gene3D G3DSA:3.40.1280.10 1 249 2.1E-70 T 28-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal CO689_RS13285 fcdc4c953e7ff0a6f6967f30c26eeb8f 250 PIRSF PIRSF015601 1 249 3.2E-60 T 28-03-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CO689_RS05435 b03fb418068413fe140fc4296e00c2d9 338 Gene3D G3DSA:3.40.50.300 1 254 1.3E-76 T 28-03-2018 CO689_RS05435 b03fb418068413fe140fc4296e00c2d9 338 Pfam PF09383 NIL domain 266 336 8.5E-14 T 28-03-2018 IPR018449 NIL domain CO689_RS05435 b03fb418068413fe140fc4296e00c2d9 338 SMART SM00382 30 226 8.6E-13 T 28-03-2018 IPR003593 AAA+ ATPase domain CO689_RS05435 b03fb418068413fe140fc4296e00c2d9 338 SUPERFAMILY SSF55021 252 337 9.73E-16 T 28-03-2018 CO689_RS05435 b03fb418068413fe140fc4296e00c2d9 338 Gene3D G3DSA:3.30.70.260 255 338 2.0E-16 T 28-03-2018 CO689_RS05435 b03fb418068413fe140fc4296e00c2d9 338 SMART SM00930 262 337 1.7E-16 T 28-03-2018 IPR018449 NIL domain CO689_RS05435 b03fb418068413fe140fc4296e00c2d9 338 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CO689_RS05435 b03fb418068413fe140fc4296e00c2d9 338 SUPERFAMILY SSF52540 1 239 1.4E-81 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CO689_RS05435 b03fb418068413fe140fc4296e00c2d9 338 Pfam PF00005 ABC transporter 21 169 2.8E-36 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CO689_RS13315 edd2956a26e88fdf65700918a7992ca6 373 SUPERFAMILY SSF102114 5 371 2.35E-116 T 28-03-2018 CO689_RS13315 edd2956a26e88fdf65700918a7992ca6 373 SMART SM00729 3 217 2.0E-61 T 28-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 CO689_RS13315 edd2956a26e88fdf65700918a7992ca6 373 Pfam PF06969 HemN C-terminal domain 297 359 2.6E-14 T 28-03-2018 IPR010723 HemN, C-terminal CO689_RS13315 edd2956a26e88fdf65700918a7992ca6 373 TIGRFAM TIGR00539 hemN_rel: putative oxygen-independent coproporphyrinogen III oxidase 4 356 3.8E-115 T 28-03-2018 IPR004559 Coproporphyrinogen III oxidase, oxygen-independent related GO:0004109|GO:0005737|GO:0006779|GO:0055114 CO689_RS13315 edd2956a26e88fdf65700918a7992ca6 373 Gene3D G3DSA:3.20.20.70 5 324 5.1E-51 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CO689_RS13315 edd2956a26e88fdf65700918a7992ca6 373 Pfam PF04055 Radical SAM superfamily 8 171 1.1E-21 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CO689_RS13315 edd2956a26e88fdf65700918a7992ca6 373 Gene3D G3DSA:1.10.10.10 331 365 0.008 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS08430 b723c97959a85ef4a6218ed19c71a98a 218 Pfam PF04023 FeoA domain 144 212 1.8E-5 T 28-03-2018 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 CO689_RS08430 b723c97959a85ef4a6218ed19c71a98a 218 Pfam PF01325 Iron dependent repressor, N-terminal DNA binding domain 1 60 8.7E-23 T 28-03-2018 IPR022687 DTXR-type HTH domain GO:0003677 CO689_RS08430 b723c97959a85ef4a6218ed19c71a98a 218 Gene3D G3DSA:2.30.30.90 124 213 2.3E-7 T 28-03-2018 CO689_RS08430 b723c97959a85ef4a6218ed19c71a98a 218 Gene3D G3DSA:1.10.10.10 2 70 6.1E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS08430 b723c97959a85ef4a6218ed19c71a98a 218 SMART SM00529 24 123 8.9E-43 T 28-03-2018 IPR022689 Iron dependent repressor GO:0003700|GO:0006355|GO:0046914 CO689_RS08430 b723c97959a85ef4a6218ed19c71a98a 218 Gene3D G3DSA:1.10.60.10 73 123 1.0E-22 T 28-03-2018 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 CO689_RS08430 b723c97959a85ef4a6218ed19c71a98a 218 Pfam PF02742 Iron dependent repressor, metal binding and dimerisation domain 64 131 3.7E-25 T 28-03-2018 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 CO689_RS08430 b723c97959a85ef4a6218ed19c71a98a 218 SUPERFAMILY SSF47979 63 134 8.89E-24 T 28-03-2018 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 CO689_RS08430 b723c97959a85ef4a6218ed19c71a98a 218 SUPERFAMILY SSF46785 2 62 2.95E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS00880 261962d468bbf326d70554322fc91be8 157 Pfam PF13185 GAF domain 43 145 3.0E-7 T 28-03-2018 IPR003018 GAF domain GO:0005515 CO689_RS00880 261962d468bbf326d70554322fc91be8 157 ProSitePatterns PS01320 Uncharacterized protein family UPF0067 signature. 91 108 - T 28-03-2018 IPR000614 Free Met sulfoxide reductase conserved site CO689_RS00880 261962d468bbf326d70554322fc91be8 157 Gene3D G3DSA:3.30.450.40 4 156 3.8E-19 T 28-03-2018 IPR029016 GAF domain-like CO689_RS00880 261962d468bbf326d70554322fc91be8 157 SUPERFAMILY SSF55781 5 150 8.94E-36 T 28-03-2018 IPR029016 GAF domain-like CO689_RS08240 3dd058bcff2ee677bce8ba686187f964 221 SMART SM00986 44 203 1.3E-36 T 28-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CO689_RS08240 3dd058bcff2ee677bce8ba686187f964 221 SMART SM00987 44 203 1.3E-36 T 28-03-2018 CO689_RS08240 3dd058bcff2ee677bce8ba686187f964 221 ProSitePatterns PS00130 Uracil-DNA glycosylase signature. 52 61 - T 28-03-2018 IPR018085 Uracil-DNA glycosylase, active site GO:0006281|GO:0016799 Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CO689_RS08240 3dd058bcff2ee677bce8ba686187f964 221 TIGRFAM TIGR00628 ung: uracil-DNA glycosylase 2 207 1.8E-78 T 28-03-2018 IPR002043 Uracil-DNA glycosylase family 1 GO:0004844|GO:0006281|GO:0006284 Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CO689_RS08240 3dd058bcff2ee677bce8ba686187f964 221 Hamap MF_00148 Uracil-DNA glycosylase [ung]. 4 214 37.837 T 28-03-2018 IPR002043 Uracil-DNA glycosylase family 1 GO:0004844|GO:0006281|GO:0006284 Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CO689_RS08240 3dd058bcff2ee677bce8ba686187f964 221 Pfam PF03167 Uracil DNA glycosylase superfamily 49 202 7.9E-25 T 28-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CO689_RS08240 3dd058bcff2ee677bce8ba686187f964 221 Gene3D G3DSA:3.40.470.10 1 221 3.6E-95 T 28-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CO689_RS08240 3dd058bcff2ee677bce8ba686187f964 221 SUPERFAMILY SSF52141 2 213 2.4E-87 T 28-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CO689_RS09720 3562cc94bc938fe6da2f1c29df62d73b 118 SMART SM00507 53 104 5.3E-7 T 28-03-2018 IPR003615 HNH nuclease CO689_RS09720 3562cc94bc938fe6da2f1c29df62d73b 118 Gene3D G3DSA:3.40.1800.10 45 118 1.6E-13 T 28-03-2018 CO689_RS09720 3562cc94bc938fe6da2f1c29df62d73b 118 Pfam PF01844 HNH endonuclease 66 109 4.5E-11 T 28-03-2018 IPR002711 HNH endonuclease GO:0003676|GO:0004519 CO689_RS03150 f399f1c06828903ad138fb33ed3d55b0 221 ProSitePatterns PS00474 Ribosomal protein L3 signature. 110 133 - T 28-03-2018 IPR019926 Ribosomal protein L3, conserved site CO689_RS03150 f399f1c06828903ad138fb33ed3d55b0 221 SUPERFAMILY SSF50447 1 219 3.36E-77 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain CO689_RS03150 f399f1c06828903ad138fb33ed3d55b0 221 Pfam PF00297 Ribosomal protein L3 103 217 1.8E-15 T 28-03-2018 IPR000597 Ribosomal protein L3 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CO689_RS03150 f399f1c06828903ad138fb33ed3d55b0 221 TIGRFAM TIGR03625 L3_bact: 50S ribosomal protein uL3 4 212 3.6E-83 T 28-03-2018 IPR019927 Ribosomal protein L3, bacterial/organelle-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CO689_RS03150 f399f1c06828903ad138fb33ed3d55b0 221 Gene3D G3DSA:4.10.960.10 66 173 4.5E-31 T 28-03-2018 CO689_RS03150 f399f1c06828903ad138fb33ed3d55b0 221 Hamap MF_01325_B 50S ribosomal protein L3 [rplC]. 2 215 39.466 T 28-03-2018 IPR019927 Ribosomal protein L3, bacterial/organelle-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CO689_RS10010 df2b41f95c0de8242b193075734094df 805 Pfam PF00361 Proton-conducting membrane transporter 128 424 4.8E-62 T 28-03-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CO689_RS10010 df2b41f95c0de8242b193075734094df 805 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 366 388 1.2E-5 T 28-03-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 CO689_RS10010 df2b41f95c0de8242b193075734094df 805 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 258 280 1.2E-5 T 28-03-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 CO689_RS10010 df2b41f95c0de8242b193075734094df 805 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 79 99 1.2E-5 T 28-03-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 CO689_RS10010 df2b41f95c0de8242b193075734094df 805 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 240 266 1.8E-42 T 28-03-2018 CO689_RS10010 df2b41f95c0de8242b193075734094df 805 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 218 239 1.8E-42 T 28-03-2018 CO689_RS10010 df2b41f95c0de8242b193075734094df 805 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 435 454 1.8E-42 T 28-03-2018 CO689_RS10010 df2b41f95c0de8242b193075734094df 805 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 308 320 1.8E-42 T 28-03-2018 CO689_RS10010 df2b41f95c0de8242b193075734094df 805 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 77 102 1.8E-42 T 28-03-2018 CO689_RS10010 df2b41f95c0de8242b193075734094df 805 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 152 173 1.8E-42 T 28-03-2018 CO689_RS10010 df2b41f95c0de8242b193075734094df 805 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 105 125 1.8E-42 T 28-03-2018 CO689_RS10010 df2b41f95c0de8242b193075734094df 805 Pfam PF13244 Domain of unknown function (DUF4040) 630 694 2.4E-22 T 28-03-2018 IPR025383 Domain of unknown function DUF4040 CO689_RS10010 df2b41f95c0de8242b193075734094df 805 Pfam PF00662 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus 64 115 2.8E-11 T 28-03-2018 IPR001516 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminal Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CO689_RS10010 df2b41f95c0de8242b193075734094df 805 TIGRFAM TIGR00940 2a6301s01: monovalent cation:proton antiporter 4 792 0.0 T 28-03-2018 IPR005663 Monovalent cation proton antiporter subunit A GO:0015077|GO:0030004 CO689_RS06140 adb1e163f0a217324c87ef8285526f00 147 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 5 145 7.2E-35 T 28-03-2018 IPR002178 PTS EIIA type-2 domain CO689_RS06140 adb1e163f0a217324c87ef8285526f00 147 SUPERFAMILY SSF55804 3 145 2.22E-36 T 28-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 CO689_RS06140 adb1e163f0a217324c87ef8285526f00 147 Gene3D G3DSA:3.40.930.10 2 147 5.6E-34 T 28-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 CO689_RS13025 b68f18a51a5281f4a8632b48bcf57411 450 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 286 293 - T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CO689_RS13025 b68f18a51a5281f4a8632b48bcf57411 450 Gene3D G3DSA:3.30.470.20 203 445 1.0E-96 T 28-03-2018 CO689_RS13025 b68f18a51a5281f4a8632b48bcf57411 450 SUPERFAMILY SSF52440 1 112 4.6E-47 T 28-03-2018 IPR016185 Pre-ATP-grasp domain CO689_RS13025 b68f18a51a5281f4a8632b48bcf57411 450 SMART SM00878 336 442 4.1E-58 T 28-03-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CO689_RS13025 b68f18a51a5281f4a8632b48bcf57411 450 Gene3D G3DSA:3.30.1490.20 129 201 1.4E-20 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CO689_RS13025 b68f18a51a5281f4a8632b48bcf57411 450 Gene3D G3DSA:3.40.50.20 1 128 8.6E-49 T 28-03-2018 CO689_RS13025 b68f18a51a5281f4a8632b48bcf57411 450 SUPERFAMILY SSF56059 82 350 1.85E-69 T 28-03-2018 CO689_RS13025 b68f18a51a5281f4a8632b48bcf57411 450 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 115 322 1.8E-80 T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CO689_RS13025 b68f18a51a5281f4a8632b48bcf57411 450 TIGRFAM TIGR00514 accC: acetyl-CoA carboxylase, biotin carboxylase subunit 1 448 3.3E-218 T 28-03-2018 IPR004549 Acetyl-CoA carboxylase, biotin carboxylase GO:0016874 CO689_RS13025 b68f18a51a5281f4a8632b48bcf57411 450 Pfam PF02785 Biotin carboxylase C-terminal domain 336 443 8.6E-37 T 28-03-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CO689_RS13025 b68f18a51a5281f4a8632b48bcf57411 450 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 152 166 - T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CO689_RS13025 b68f18a51a5281f4a8632b48bcf57411 450 SUPERFAMILY SSF51246 331 443 3.14E-42 T 28-03-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 CO689_RS13025 b68f18a51a5281f4a8632b48bcf57411 450 Pfam PF00289 Biotin carboxylase, N-terminal domain 2 109 8.5E-44 T 28-03-2018 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CO689_RS13240 8209171594bde45cb724f73b1b62810d 135 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 4 103 4.9E-12 T 28-03-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain CO689_RS13240 8209171594bde45cb724f73b1b62810d 135 SUPERFAMILY SSF53927 5 133 1.02E-39 T 28-03-2018 IPR016193 Cytidine deaminase-like GO:0003824 CO689_RS13240 8209171594bde45cb724f73b1b62810d 135 Gene3D G3DSA:3.40.140.10 2 134 1.7E-41 T 28-03-2018 CO689_RS13240 8209171594bde45cb724f73b1b62810d 135 TIGRFAM TIGR01354 cyt_deam_tetra: cytidine deaminase 8 133 2.2E-45 T 28-03-2018 IPR006262 Cytidine deaminase, homotetrameric GO:0004126|GO:0008270|GO:0009972 KEGG: 00240+3.5.4.5|KEGG: 00983+3.5.4.5|MetaCyc: PWY-6556|MetaCyc: PWY-7181|MetaCyc: PWY-7193|MetaCyc: PWY-7199|Reactome: R-HSA-6798695|Reactome: R-HSA-73614 CO689_RS05415 2cefebc128258e6ea7a8085aaf908da5 2076 Gene3D G3DSA:2.20.230.10 1421 1479 0.0013 T 28-03-2018 CO689_RS05415 2cefebc128258e6ea7a8085aaf908da5 2076 TIGRFAM TIGR01168 YSIRK_signal: gram-positive signal peptide, YSIRK family 1 40 1.0E-9 T 28-03-2018 IPR005877 YSIRK Gram-positive signal peptide GO:0016020 CO689_RS05415 2cefebc128258e6ea7a8085aaf908da5 2076 Gene3D G3DSA:2.20.230.10 751 827 7.5E-10 T 28-03-2018 CO689_RS05415 2cefebc128258e6ea7a8085aaf908da5 2076 Pfam PF04650 YSIRK type signal peptide 4 29 9.0E-10 T 28-03-2018 IPR005877 YSIRK Gram-positive signal peptide GO:0016020 CO689_RS05415 2cefebc128258e6ea7a8085aaf908da5 2076 Pfam PF08428 Rib/alpha-like repeat 1749 1815 3.5E-8 T 28-03-2018 CO689_RS05415 2cefebc128258e6ea7a8085aaf908da5 2076 Pfam PF08428 Rib/alpha-like repeat 1577 1643 1.4E-7 T 28-03-2018 CO689_RS05415 2cefebc128258e6ea7a8085aaf908da5 2076 Pfam PF08428 Rib/alpha-like repeat 1491 1557 9.3E-8 T 28-03-2018 CO689_RS05415 2cefebc128258e6ea7a8085aaf908da5 2076 Pfam PF08428 Rib/alpha-like repeat 1933 1958 0.4 T 28-03-2018 CO689_RS05415 2cefebc128258e6ea7a8085aaf908da5 2076 Pfam PF08428 Rib/alpha-like repeat 1664 1729 1.3E-7 T 28-03-2018 CO689_RS05415 2cefebc128258e6ea7a8085aaf908da5 2076 Pfam PF08428 Rib/alpha-like repeat 1845 1914 2.0E-5 T 28-03-2018 CO689_RS05415 2cefebc128258e6ea7a8085aaf908da5 2076 Gene3D G3DSA:2.60.40.10 1824 1910 7.6E-4 T 28-03-2018 IPR013783 Immunoglobulin-like fold CO689_RS05415 2cefebc128258e6ea7a8085aaf908da5 2076 TIGRFAM TIGR02331 rib_alpha: Rib/alpha/Esp surface antigen repeat 1659 1740 7.3E-10 T 28-03-2018 IPR012706 Rib/alpha/Esp surface antigen CO689_RS05415 2cefebc128258e6ea7a8085aaf908da5 2076 TIGRFAM TIGR02331 rib_alpha: Rib/alpha/Esp surface antigen repeat 1573 1654 5.4E-12 T 28-03-2018 IPR012706 Rib/alpha/Esp surface antigen CO689_RS05415 2cefebc128258e6ea7a8085aaf908da5 2076 TIGRFAM TIGR02331 rib_alpha: Rib/alpha/Esp surface antigen repeat 1745 1826 9.8E-12 T 28-03-2018 IPR012706 Rib/alpha/Esp surface antigen CO689_RS05415 2cefebc128258e6ea7a8085aaf908da5 2076 Pfam PF00746 LPXTG cell wall anchor motif 2032 2073 3.3E-8 T 28-03-2018 IPR019948 Gram-positive LPXTG cell wall anchor CO689_RS05415 2cefebc128258e6ea7a8085aaf908da5 2076 Gene3D G3DSA:2.20.230.10 828 904 3.8E-11 T 28-03-2018 CO689_RS05415 2cefebc128258e6ea7a8085aaf908da5 2076 Gene3D G3DSA:2.20.230.10 1036 1091 0.13 T 28-03-2018 CO689_RS05415 2cefebc128258e6ea7a8085aaf908da5 2076 Gene3D G3DSA:2.20.230.10 1294 1348 0.084 T 28-03-2018 CO689_RS05415 2cefebc128258e6ea7a8085aaf908da5 2076 Gene3D G3DSA:2.20.230.10 957 1033 1.1E-14 T 28-03-2018 CO689_RS05415 2cefebc128258e6ea7a8085aaf908da5 2076 Gene3D G3DSA:2.20.230.10 1349 1420 1.9E-14 T 28-03-2018 CO689_RS05415 2cefebc128258e6ea7a8085aaf908da5 2076 Gene3D G3DSA:2.20.230.10 1215 1291 7.2E-17 T 28-03-2018 CO689_RS05415 2cefebc128258e6ea7a8085aaf908da5 2076 Gene3D G3DSA:2.20.230.10 1092 1162 3.0E-17 T 28-03-2018 CO689_RS05415 2cefebc128258e6ea7a8085aaf908da5 2076 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 2039 2071 7.7E-6 T 28-03-2018 CO689_RS05415 2cefebc128258e6ea7a8085aaf908da5 2076 SMART SM01208 956 1037 1.1E-9 T 28-03-2018 IPR011098 G5 domain CO689_RS05415 2cefebc128258e6ea7a8085aaf908da5 2076 SMART SM01208 1085 1166 5.1E-11 T 28-03-2018 IPR011098 G5 domain CO689_RS05415 2cefebc128258e6ea7a8085aaf908da5 2076 SMART SM01208 1428 1474 0.71 T 28-03-2018 IPR011098 G5 domain CO689_RS05415 2cefebc128258e6ea7a8085aaf908da5 2076 SMART SM01208 1214 1295 2.6E-10 T 28-03-2018 IPR011098 G5 domain CO689_RS05415 2cefebc128258e6ea7a8085aaf908da5 2076 SMART SM01208 1343 1424 6.5E-12 T 28-03-2018 IPR011098 G5 domain CO689_RS05415 2cefebc128258e6ea7a8085aaf908da5 2076 SMART SM01208 827 908 4.7E-7 T 28-03-2018 IPR011098 G5 domain CO689_RS05415 2cefebc128258e6ea7a8085aaf908da5 2076 SMART SM01208 749 826 5.8E-9 T 28-03-2018 IPR011098 G5 domain CO689_RS05415 2cefebc128258e6ea7a8085aaf908da5 2076 Pfam PF07501 G5 domain 1349 1420 2.4E-10 T 28-03-2018 IPR011098 G5 domain CO689_RS05415 2cefebc128258e6ea7a8085aaf908da5 2076 Pfam PF07501 G5 domain 833 903 1.3E-6 T 28-03-2018 IPR011098 G5 domain CO689_RS05415 2cefebc128258e6ea7a8085aaf908da5 2076 Pfam PF07501 G5 domain 962 1032 3.6E-9 T 28-03-2018 IPR011098 G5 domain CO689_RS05415 2cefebc128258e6ea7a8085aaf908da5 2076 Pfam PF07501 G5 domain 1220 1290 6.4E-10 T 28-03-2018 IPR011098 G5 domain CO689_RS05415 2cefebc128258e6ea7a8085aaf908da5 2076 Pfam PF07501 G5 domain 1091 1161 3.6E-10 T 28-03-2018 IPR011098 G5 domain CO689_RS05415 2cefebc128258e6ea7a8085aaf908da5 2076 Pfam PF07501 G5 domain 757 826 8.3E-8 T 28-03-2018 IPR011098 G5 domain CO689_RS05415 2cefebc128258e6ea7a8085aaf908da5 2076 Gene3D G3DSA:2.60.40.10 1911 2002 3.7E-13 T 28-03-2018 IPR013783 Immunoglobulin-like fold CO689_RS05415 2cefebc128258e6ea7a8085aaf908da5 2076 Pfam PF17041 E domain 1040 1084 1.4E-11 T 28-03-2018 IPR031477 E domain CO689_RS05415 2cefebc128258e6ea7a8085aaf908da5 2076 Pfam PF17041 E domain 1169 1213 9.0E-11 T 28-03-2018 IPR031477 E domain CO689_RS05415 2cefebc128258e6ea7a8085aaf908da5 2076 Pfam PF17041 E domain 1431 1471 6.0E-9 T 28-03-2018 IPR031477 E domain CO689_RS05415 2cefebc128258e6ea7a8085aaf908da5 2076 Pfam PF17041 E domain 1298 1342 1.4E-11 T 28-03-2018 IPR031477 E domain CO689_RS05415 2cefebc128258e6ea7a8085aaf908da5 2076 Pfam PF17041 E domain 911 955 1.5E-11 T 28-03-2018 IPR031477 E domain CO689_RS01285 424d3c786d22fabea7e345f4d69c69b7 177 Pfam PF08279 HTH domain 7 60 2.3E-13 T 28-03-2018 IPR013196 Helix-turn-helix, type 11 CO689_RS01285 424d3c786d22fabea7e345f4d69c69b7 177 Pfam PF02829 3H domain 74 170 6.2E-33 T 28-03-2018 IPR004173 3H domain GO:0036094 CO689_RS01285 424d3c786d22fabea7e345f4d69c69b7 177 Gene3D G3DSA:1.10.10.10 1 63 1.0E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS01285 424d3c786d22fabea7e345f4d69c69b7 177 ProDom PD469575 TRANSCRIPTION DNA-BINDING REGULATION TRANSCRIPTIONAL REGULATOR REPRESSOR FAMILY BIOTIN REGULATOR 3H 77 170 1.0E-18 T 28-03-2018 IPR004173 3H domain GO:0036094 CO689_RS01285 424d3c786d22fabea7e345f4d69c69b7 177 PIRSF PIRSF037847 2 173 9.6E-61 T 28-03-2018 IPR026043 Transcription repressor NadR CO689_RS01285 424d3c786d22fabea7e345f4d69c69b7 177 SUPERFAMILY SSF75500 70 172 1.57E-33 T 28-03-2018 IPR004173 3H domain GO:0036094 CO689_RS01285 424d3c786d22fabea7e345f4d69c69b7 177 SUPERFAMILY SSF46785 4 61 2.21E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS01285 424d3c786d22fabea7e345f4d69c69b7 177 Gene3D G3DSA:3.30.1340.20 71 171 4.5E-35 T 28-03-2018 IPR004173 3H domain GO:0036094 CO689_RS02995 83397919bda389cb3bfdcff0da5414fa 267 Hamap MF_00171 tRNA pseudouridine synthase A [truA]. 1 243 34.221 T 28-03-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 CO689_RS02995 83397919bda389cb3bfdcff0da5414fa 267 SUPERFAMILY SSF55120 2 246 8.92E-81 T 28-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 CO689_RS02995 83397919bda389cb3bfdcff0da5414fa 267 PIRSF PIRSF001430 1 255 8.6E-78 T 28-03-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 CO689_RS02995 83397919bda389cb3bfdcff0da5414fa 267 Gene3D G3DSA:3.30.70.580 1 104 7.9E-30 T 28-03-2018 CO689_RS02995 83397919bda389cb3bfdcff0da5414fa 267 TIGRFAM TIGR00071 hisT_truA: tRNA pseudouridine(38-40) synthase 2 238 3.6E-68 T 28-03-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 CO689_RS02995 83397919bda389cb3bfdcff0da5414fa 267 Pfam PF01416 tRNA pseudouridine synthase 8 103 1.2E-10 T 28-03-2018 IPR020097 Pseudouridine synthase I, TruA, alpha/beta domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 CO689_RS02995 83397919bda389cb3bfdcff0da5414fa 267 Pfam PF01416 tRNA pseudouridine synthase 142 240 2.5E-27 T 28-03-2018 IPR020097 Pseudouridine synthase I, TruA, alpha/beta domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 CO689_RS02995 83397919bda389cb3bfdcff0da5414fa 267 Gene3D G3DSA:3.30.70.660 105 242 6.6E-36 T 28-03-2018 IPR020095 Pseudouridine synthase I, TruA, C-terminal GO:0001522|GO:0003723|GO:0009451|GO:0009982 CO689_RS01645 a1e6ed7450a824f5945db96e38ee97c3 327 Pfam PF04307 LexA-binding, inner membrane-associated putative hydrolase 1 168 6.1E-28 T 28-03-2018 IPR007404 LexA-binding, inner membrane-associated putative hydrolase CO689_RS03045 8b5fe83f5e6f28769397c1bb29e6d301 216 TIGRFAM TIGR01351 adk: adenylate kinase 2 212 1.5E-81 T 28-03-2018 IPR006259 Adenylate kinase subfamily GO:0004017|GO:0005524|GO:0016776 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219 CO689_RS03045 8b5fe83f5e6f28769397c1bb29e6d301 216 ProSitePatterns PS00113 Adenylate kinase signature. 81 92 - T 28-03-2018 IPR033690 Adenylate kinase, conserved site KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 CO689_RS03045 8b5fe83f5e6f28769397c1bb29e6d301 216 Hamap MF_00235 Adenylate kinase [adk]. 1 213 53.059 T 28-03-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 CO689_RS03045 8b5fe83f5e6f28769397c1bb29e6d301 216 SUPERFAMILY SSF52540 1 213 5.23E-47 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CO689_RS03045 8b5fe83f5e6f28769397c1bb29e6d301 216 Pfam PF00406 Adenylate kinase 5 190 4.4E-61 T 28-03-2018 CO689_RS03045 8b5fe83f5e6f28769397c1bb29e6d301 216 PRINTS PR00094 Adenylate kinase signature 4 17 2.2E-33 T 28-03-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 CO689_RS03045 8b5fe83f5e6f28769397c1bb29e6d301 216 PRINTS PR00094 Adenylate kinase signature 81 97 2.2E-33 T 28-03-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 CO689_RS03045 8b5fe83f5e6f28769397c1bb29e6d301 216 PRINTS PR00094 Adenylate kinase signature 177 191 2.2E-33 T 28-03-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 CO689_RS03045 8b5fe83f5e6f28769397c1bb29e6d301 216 PRINTS PR00094 Adenylate kinase signature 160 175 2.2E-33 T 28-03-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 CO689_RS03045 8b5fe83f5e6f28769397c1bb29e6d301 216 PRINTS PR00094 Adenylate kinase signature 32 46 2.2E-33 T 28-03-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 CO689_RS03045 8b5fe83f5e6f28769397c1bb29e6d301 216 Pfam PF05191 Adenylate kinase, active site lid 127 162 4.9E-17 T 28-03-2018 IPR007862 Adenylate kinase, active site lid domain GO:0004017 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219 CO689_RS03045 8b5fe83f5e6f28769397c1bb29e6d301 216 Gene3D G3DSA:3.40.50.300 1 216 1.8E-67 T 28-03-2018 CO689_RS10865 23e3e43299a6654e1b1fbf22c63d39f7 325 SMART SM00861 4 179 2.0E-56 T 28-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain CO689_RS10865 23e3e43299a6654e1b1fbf22c63d39f7 325 Pfam PF02780 Transketolase, C-terminal domain 194 315 2.8E-40 T 28-03-2018 IPR033248 Transketolase, C-terminal domain CO689_RS10865 23e3e43299a6654e1b1fbf22c63d39f7 325 Gene3D G3DSA:3.40.50.920 195 324 2.2E-37 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CO689_RS10865 23e3e43299a6654e1b1fbf22c63d39f7 325 Pfam PF02779 Transketolase, pyrimidine binding domain 3 178 1.1E-38 T 28-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain CO689_RS10865 23e3e43299a6654e1b1fbf22c63d39f7 325 SUPERFAMILY SSF52518 3 192 6.48E-64 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CO689_RS10865 23e3e43299a6654e1b1fbf22c63d39f7 325 SUPERFAMILY SSF52922 188 325 3.4E-41 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CO689_RS10865 23e3e43299a6654e1b1fbf22c63d39f7 325 Gene3D G3DSA:3.40.50.970 1 194 7.6E-62 T 28-03-2018 CO689_RS04275 a6a9d14cd1a300e1e4c7e44cd8423405 424 Gene3D G3DSA:1.20.1250.20 215 422 3.4E-27 T 28-03-2018 CO689_RS04275 a6a9d14cd1a300e1e4c7e44cd8423405 424 Pfam PF07690 Major Facilitator Superfamily 16 375 4.7E-57 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CO689_RS04275 a6a9d14cd1a300e1e4c7e44cd8423405 424 SUPERFAMILY SSF103473 4 414 7.19E-82 T 28-03-2018 IPR020846 Major facilitator superfamily domain CO689_RS04275 a6a9d14cd1a300e1e4c7e44cd8423405 424 Gene3D G3DSA:1.20.1250.20 1 204 1.6E-39 T 28-03-2018 CO689_RS04305 eb02f451a52790c047044db0bd2ee4cd 286 Pfam PF02311 AraC-like ligand binding domain 20 154 7.2E-21 T 28-03-2018 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 CO689_RS04305 eb02f451a52790c047044db0bd2ee4cd 286 Pfam PF12833 Helix-turn-helix domain 198 275 1.8E-19 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CO689_RS04305 eb02f451a52790c047044db0bd2ee4cd 286 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 228 270 - T 28-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 CO689_RS04305 eb02f451a52790c047044db0bd2ee4cd 286 Gene3D G3DSA:1.10.10.60 229 286 3.0E-11 T 28-03-2018 CO689_RS04305 eb02f451a52790c047044db0bd2ee4cd 286 SUPERFAMILY SSF51215 14 159 3.4E-21 T 28-03-2018 CO689_RS04305 eb02f451a52790c047044db0bd2ee4cd 286 SMART SM00342 191 274 6.4E-26 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CO689_RS04305 eb02f451a52790c047044db0bd2ee4cd 286 SUPERFAMILY SSF46689 227 278 1.3E-9 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CO689_RS04305 eb02f451a52790c047044db0bd2ee4cd 286 SUPERFAMILY SSF46689 178 225 2.74E-7 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CO689_RS04305 eb02f451a52790c047044db0bd2ee4cd 286 Gene3D G3DSA:2.60.120.280 32 185 7.3E-19 T 28-03-2018 CO689_RS04305 eb02f451a52790c047044db0bd2ee4cd 286 Gene3D G3DSA:1.10.10.60 186 228 3.8E-11 T 28-03-2018 CO689_RS01815 b16ae4284acb2ab9f603bace9a16b77c 667 SUPERFAMILY SSF50249 310 392 5.65E-27 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CO689_RS01815 b16ae4284acb2ab9f603bace9a16b77c 667 ProSitePatterns PS01056 NAD-dependent DNA ligase signature 2. 324 339 - T 28-03-2018 IPR033136 NAD-dependent DNA ligase, conserved site CO689_RS01815 b16ae4284acb2ab9f603bace9a16b77c 667 Gene3D G3DSA:3.30.470.30 116 231 3.6E-50 T 28-03-2018 CO689_RS01815 b16ae4284acb2ab9f603bace9a16b77c 667 ProSitePatterns PS01055 NAD-dependent DNA ligase signature 1. 112 141 - T 28-03-2018 IPR018239 NAD-dependent DNA ligase, active site CO689_RS01815 b16ae4284acb2ab9f603bace9a16b77c 667 Hamap MF_01588 DNA ligase [ligA]. 2 662 52.01 T 28-03-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 CO689_RS01815 b16ae4284acb2ab9f603bace9a16b77c 667 Gene3D G3DSA:2.40.50.140 315 382 7.2E-32 T 28-03-2018 CO689_RS01815 b16ae4284acb2ab9f603bace9a16b77c 667 Gene3D G3DSA:1.10.150.20 495 544 5.6E-15 T 28-03-2018 CO689_RS01815 b16ae4284acb2ab9f603bace9a16b77c 667 SMART SM00532 3 440 1.5E-269 T 28-03-2018 IPR013840 NAD-dependent DNA ligase, N-terminal GO:0003911 CO689_RS01815 b16ae4284acb2ab9f603bace9a16b77c 667 Gene3D G3DSA:3.30.1490.70 232 314 1.4E-28 T 28-03-2018 CO689_RS01815 b16ae4284acb2ab9f603bace9a16b77c 667 Gene3D G3DSA:1.10.287.610 1 66 2.0E-22 T 28-03-2018 CO689_RS01815 b16ae4284acb2ab9f603bace9a16b77c 667 PIRSF PIRSF001604 1 666 2.3E-255 T 28-03-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 CO689_RS01815 b16ae4284acb2ab9f603bace9a16b77c 667 Pfam PF03120 NAD-dependent DNA ligase OB-fold domain 315 390 6.2E-34 T 28-03-2018 IPR004150 NAD-dependent DNA ligase, OB-fold GO:0003911|GO:0006260|GO:0006281 CO689_RS01815 b16ae4284acb2ab9f603bace9a16b77c 667 Pfam PF03119 NAD-dependent DNA ligase C4 zinc finger domain 400 426 5.8E-11 T 28-03-2018 IPR004149 Zinc-finger, NAD-dependent DNA ligase C4-type GO:0003911|GO:0006260|GO:0006281 CO689_RS01815 b16ae4284acb2ab9f603bace9a16b77c 667 Pfam PF01653 NAD-dependent DNA ligase adenylation domain 5 311 1.9E-129 T 28-03-2018 IPR013839 NAD-dependent DNA ligase, adenylation GO:0003911 CO689_RS01815 b16ae4284acb2ab9f603bace9a16b77c 667 Pfam PF12826 Helix-hairpin-helix motif 503 565 2.4E-18 T 28-03-2018 CO689_RS01815 b16ae4284acb2ab9f603bace9a16b77c 667 SUPERFAMILY SSF52113 588 660 1.96E-16 T 28-03-2018 IPR001357 BRCT domain CO689_RS01815 b16ae4284acb2ab9f603bace9a16b77c 667 SUPERFAMILY SSF47781 396 576 8.9E-61 T 28-03-2018 IPR010994 RuvA domain 2-like CO689_RS01815 b16ae4284acb2ab9f603bace9a16b77c 667 SMART SM00278 438 457 110.0 T 28-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 CO689_RS01815 b16ae4284acb2ab9f603bace9a16b77c 667 SMART SM00278 536 555 94.0 T 28-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 CO689_RS01815 b16ae4284acb2ab9f603bace9a16b77c 667 SMART SM00278 472 491 3.1 T 28-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 CO689_RS01815 b16ae4284acb2ab9f603bace9a16b77c 667 SUPERFAMILY SSF56091 3 311 1.89E-121 T 28-03-2018 CO689_RS01815 b16ae4284acb2ab9f603bace9a16b77c 667 Gene3D G3DSA:3.40.50.10190 608 662 4.1E-16 T 28-03-2018 IPR001357 BRCT domain CO689_RS01815 b16ae4284acb2ab9f603bace9a16b77c 667 TIGRFAM TIGR00575 dnlj: DNA ligase, NAD-dependent 11 658 5.8E-263 T 28-03-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 CO689_RS01815 b16ae4284acb2ab9f603bace9a16b77c 667 Pfam PF00533 BRCA1 C Terminus (BRCT) domain 591 656 1.0E-10 T 28-03-2018 IPR001357 BRCT domain CO689_RS01815 b16ae4284acb2ab9f603bace9a16b77c 667 SMART SM00292 588 662 5.0E-5 T 28-03-2018 IPR001357 BRCT domain CO689_RS01815 b16ae4284acb2ab9f603bace9a16b77c 667 Pfam PF14520 Helix-hairpin-helix domain 438 491 8.0E-6 T 28-03-2018 CO689_RS01815 b16ae4284acb2ab9f603bace9a16b77c 667 Gene3D G3DSA:1.10.150.20 424 494 4.3E-29 T 28-03-2018 CO689_RS01815 b16ae4284acb2ab9f603bace9a16b77c 667 Gene3D G3DSA:1.10.150.20 545 607 0.0015 T 28-03-2018 CO689_RS06710 f31455401c3677dac185756e8b11c69e 174 Gene3D G3DSA:2.40.30.20 97 163 0.016 T 28-03-2018 IPR023366 ATP synthase subunit alpha-like domain KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CO689_RS06710 f31455401c3677dac185756e8b11c69e 174 Pfam PF07563 Protein of unknown function (DUF1541) 53 103 3.3E-26 T 28-03-2018 IPR011438 Domain of unknown function DUF1541 CO689_RS06710 f31455401c3677dac185756e8b11c69e 174 Pfam PF07563 Protein of unknown function (DUF1541) 117 167 1.8E-21 T 28-03-2018 IPR011438 Domain of unknown function DUF1541 CO689_RS06710 f31455401c3677dac185756e8b11c69e 174 Gene3D G3DSA:2.30.30.30 45 85 0.035 T 28-03-2018 IPR014722 Ribosomal protein L2 domain 2 CO689_RS03170 06226d7e6f4b4ab56a4b5708ac820c0e 444 PIRSF PIRSF005353 1 444 1.0E-171 T 28-03-2018 IPR026033 Purine permease PbuG-like CO689_RS03170 06226d7e6f4b4ab56a4b5708ac820c0e 444 Pfam PF00860 Permease family 16 404 6.0E-42 T 28-03-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 CO689_RS02395 fa0921cc51449742f775e655d7dee8ec 226 TIGRFAM TIGR04306 salvage_TenA: thiaminase II 11 218 3.5E-67 T 28-03-2018 IPR027574 Thiaminase II GO:0006772|GO:0050334 KEGG: 00730+3.5.99.2|MetaCyc: PWY-6899|MetaCyc: PWY-7356 CO689_RS02395 fa0921cc51449742f775e655d7dee8ec 226 SUPERFAMILY SSF48613 3 224 4.9E-52 T 28-03-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 CO689_RS02395 fa0921cc51449742f775e655d7dee8ec 226 Gene3D G3DSA:1.20.910.10 1 225 8.3E-39 T 28-03-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 CO689_RS02395 fa0921cc51449742f775e655d7dee8ec 226 Pfam PF03070 TENA/THI-4/PQQC family 9 217 1.7E-56 T 28-03-2018 IPR004305 Thiaminase-2/PQQC CO689_RS12150 3aee6d2a4a40534ba661b93935d3db2f 319 Pfam PF00294 pfkB family carbohydrate kinase 1 307 2.7E-70 T 28-03-2018 IPR011611 Carbohydrate kinase PfkB CO689_RS12150 3aee6d2a4a40534ba661b93935d3db2f 319 Gene3D G3DSA:3.40.1190.20 3 319 4.8E-66 T 28-03-2018 IPR029056 Ribokinase-like CO689_RS12150 3aee6d2a4a40534ba661b93935d3db2f 319 SUPERFAMILY SSF53613 1 315 3.9E-75 T 28-03-2018 IPR029056 Ribokinase-like CO689_RS12150 3aee6d2a4a40534ba661b93935d3db2f 319 ProSitePatterns PS00583 pfkB family of carbohydrate kinases signature 1. 34 58 - T 28-03-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 CO689_RS12925 274a08eb1892a1fb81b185afc3e7a3a7 494 Gene3D G3DSA:3.40.50.720 7 192 3.4E-68 T 28-03-2018 CO689_RS12925 274a08eb1892a1fb81b185afc3e7a3a7 494 Gene3D G3DSA:3.30.360.10 193 492 8.7E-120 T 28-03-2018 CO689_RS12925 274a08eb1892a1fb81b185afc3e7a3a7 494 SUPERFAMILY SSF51735 8 194 1.24E-59 T 28-03-2018 IPR016040 NAD(P)-binding domain CO689_RS12925 274a08eb1892a1fb81b185afc3e7a3a7 494 TIGRFAM TIGR00871 zwf: glucose-6-phosphate dehydrogenase 9 491 1.7E-189 T 28-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 CO689_RS12925 274a08eb1892a1fb81b185afc3e7a3a7 494 Hamap MF_00966 Glucose-6-phosphate 1-dehydrogenase [zwf]. 9 491 82.029 T 28-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 CO689_RS12925 274a08eb1892a1fb81b185afc3e7a3a7 494 PIRSF PIRSF000110 1 493 8.9E-181 T 28-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 CO689_RS12925 274a08eb1892a1fb81b185afc3e7a3a7 494 Pfam PF00479 Glucose-6-phosphate dehydrogenase, NAD binding domain 14 191 2.4E-61 T 28-03-2018 IPR022674 Glucose-6-phosphate dehydrogenase, NAD-binding GO:0004345|GO:0006006|GO:0050661|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 CO689_RS12925 274a08eb1892a1fb81b185afc3e7a3a7 494 SUPERFAMILY SSF55347 181 491 2.98E-110 T 28-03-2018 CO689_RS12925 274a08eb1892a1fb81b185afc3e7a3a7 494 Pfam PF02781 Glucose-6-phosphate dehydrogenase, C-terminal domain 194 489 8.2E-111 T 28-03-2018 IPR022675 Glucose-6-phosphate dehydrogenase, C-terminal GO:0004345|GO:0006006|GO:0050661|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 CO689_RS12925 274a08eb1892a1fb81b185afc3e7a3a7 494 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 332 358 4.3E-47 T 28-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 CO689_RS12925 274a08eb1892a1fb81b185afc3e7a3a7 494 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 223 240 4.3E-47 T 28-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 CO689_RS12925 274a08eb1892a1fb81b185afc3e7a3a7 494 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 171 199 4.3E-47 T 28-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 CO689_RS12925 274a08eb1892a1fb81b185afc3e7a3a7 494 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 241 257 4.3E-47 T 28-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 CO689_RS12925 274a08eb1892a1fb81b185afc3e7a3a7 494 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 147 160 4.3E-47 T 28-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 CO689_RS10985 ddc577b1c12aeda044c93d60563510c0 346 SUPERFAMILY SSF55797 233 331 1.88E-6 T 28-03-2018 IPR014044 CAP domain CO689_RS10985 ddc577b1c12aeda044c93d60563510c0 346 Pfam PF14504 CAP-associated N-terminal 67 204 8.2E-36 T 28-03-2018 IPR029410 CAP-associated domain CO689_RS10985 ddc577b1c12aeda044c93d60563510c0 346 Gene3D G3DSA:3.40.33.10 224 343 5.5E-4 T 28-03-2018 IPR014044 CAP domain CO689_RS10985 ddc577b1c12aeda044c93d60563510c0 346 Pfam PF00188 Cysteine-rich secretory protein family 236 334 1.8E-7 T 28-03-2018 IPR014044 CAP domain CO689_RS11340 bc0ad58ee58e3e4ea83ef4794fa584f1 423 SUPERFAMILY SSF51556 53 364 4.35E-114 T 28-03-2018 IPR032466 Metal-dependent hydrolase CO689_RS11340 bc0ad58ee58e3e4ea83ef4794fa584f1 423 Gene3D G3DSA:2.30.40.10 1 66 6.1E-21 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CO689_RS11340 bc0ad58ee58e3e4ea83ef4794fa584f1 423 ProSitePatterns PS00483 Dihydroorotase signature 2. 301 312 - T 28-03-2018 IPR002195 Dihydroorotase, conserved site GO:0016812 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CO689_RS11340 bc0ad58ee58e3e4ea83ef4794fa584f1 423 ProSitePatterns PS00482 Dihydroorotase signature 1. 56 64 - T 28-03-2018 IPR002195 Dihydroorotase, conserved site GO:0016812 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CO689_RS11340 bc0ad58ee58e3e4ea83ef4794fa584f1 423 TIGRFAM TIGR00857 pyrC_multi: dihydroorotase, multifunctional complex type 13 422 2.8E-146 T 28-03-2018 IPR004722 Dihydroorotase GO:0004151|GO:0006221|GO:0046872 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CO689_RS11340 bc0ad58ee58e3e4ea83ef4794fa584f1 423 Gene3D G3DSA:3.20.20.140 67 405 9.3E-111 T 28-03-2018 CO689_RS11340 bc0ad58ee58e3e4ea83ef4794fa584f1 423 Hamap MF_00220_B Dihydroorotase [pyrC]. 1 423 47.415 T 28-03-2018 IPR004722 Dihydroorotase GO:0004151|GO:0006221|GO:0046872 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CO689_RS11340 bc0ad58ee58e3e4ea83ef4794fa584f1 423 SUPERFAMILY SSF51338 365 421 1.73E-27 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CO689_RS11340 bc0ad58ee58e3e4ea83ef4794fa584f1 423 SUPERFAMILY SSF51338 2 52 1.73E-27 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CO689_RS11340 bc0ad58ee58e3e4ea83ef4794fa584f1 423 Pfam PF01979 Amidohydrolase family 50 418 1.1E-48 T 28-03-2018 IPR006680 Amidohydrolase-related GO:0016787 CO689_RS07750 186598c8fa1775ca9218d6d3c309b2fb 88 SUPERFAMILY SSF55174 1 76 6.67E-19 T 28-03-2018 CO689_RS07750 186598c8fa1775ca9218d6d3c309b2fb 88 Pfam PF01479 S4 domain 1 47 1.3E-8 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CO689_RS07750 186598c8fa1775ca9218d6d3c309b2fb 88 PIRSF PIRSF038881 1 88 2.9E-31 T 28-03-2018 IPR025490 RNA-binding protein, HP1423 type CO689_RS07750 186598c8fa1775ca9218d6d3c309b2fb 88 SMART SM00363 1 62 1.3E-5 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CO689_RS07750 186598c8fa1775ca9218d6d3c309b2fb 88 Gene3D G3DSA:3.10.290.10 1 88 5.7E-16 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CO689_RS12940 458f3ac73ef8894964dc623f2ec8a6e1 374 SUPERFAMILY SSF55031 184 283 2.49E-20 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain CO689_RS12940 458f3ac73ef8894964dc623f2ec8a6e1 374 ProSitePatterns PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. 74 83 - T 28-03-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 CO689_RS12940 458f3ac73ef8894964dc623f2ec8a6e1 374 Gene3D G3DSA:3.40.630.10 1 372 2.6E-56 T 28-03-2018 CO689_RS12940 458f3ac73ef8894964dc623f2ec8a6e1 374 Pfam PF07687 Peptidase dimerisation domain 184 277 5.5E-16 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain CO689_RS12940 458f3ac73ef8894964dc623f2ec8a6e1 374 PIRSF PIRSF001123 4 101 1.6E-4 T 28-03-2018 IPR008007 Peptidase M42 CO689_RS12940 458f3ac73ef8894964dc623f2ec8a6e1 374 PIRSF PIRSF001123 102 228 1.0E-7 T 28-03-2018 IPR008007 Peptidase M42 CO689_RS12940 458f3ac73ef8894964dc623f2ec8a6e1 374 PIRSF PIRSF001123 289 374 6.4E-4 T 28-03-2018 IPR008007 Peptidase M42 CO689_RS12940 458f3ac73ef8894964dc623f2ec8a6e1 374 SUPERFAMILY SSF53187 290 370 1.86E-59 T 28-03-2018 CO689_RS12940 458f3ac73ef8894964dc623f2ec8a6e1 374 SUPERFAMILY SSF53187 5 181 1.86E-59 T 28-03-2018 CO689_RS12940 458f3ac73ef8894964dc623f2ec8a6e1 374 TIGRFAM TIGR01883 PepT-like: peptidase T-like protein 6 369 3.1E-125 T 28-03-2018 IPR010162 Peptidase M20B, peptidase T-like CO689_RS12940 458f3ac73ef8894964dc623f2ec8a6e1 374 ProSitePatterns PS00759 ArgE / dapE / ACY1 / CPG2 / yscS family signature 2. 108 146 - T 28-03-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 CO689_RS12940 458f3ac73ef8894964dc623f2ec8a6e1 374 Pfam PF01546 Peptidase family M20/M25/M40 76 369 9.9E-20 T 28-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CO689_RS13015 c0c46bd6a4f4a25b9edc6a5c78618334 129 Hamap MF_00073 N utilization substance protein B homolog [nusB]. 1 129 20.013 T 28-03-2018 IPR011605 NusB antitermination factor GO:0006353 CO689_RS13015 c0c46bd6a4f4a25b9edc6a5c78618334 129 SUPERFAMILY SSF48013 2 127 5.49E-37 T 28-03-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 CO689_RS13015 c0c46bd6a4f4a25b9edc6a5c78618334 129 TIGRFAM TIGR01951 nusB: transcription antitermination factor NusB 3 127 3.0E-39 T 28-03-2018 IPR011605 NusB antitermination factor GO:0006353 CO689_RS13015 c0c46bd6a4f4a25b9edc6a5c78618334 129 Pfam PF01029 NusB family 5 127 2.2E-34 T 28-03-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 CO689_RS13015 c0c46bd6a4f4a25b9edc6a5c78618334 129 Gene3D G3DSA:1.10.940.10 1 129 2.7E-37 T 28-03-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 CO689_RS01810 029fe580fc46efd10ba8c2949713decc 399 Pfam PF07537 CamS sex pheromone cAM373 precursor 60 390 3.0E-112 T 28-03-2018 IPR011426 CamS sex pheromone cAM373 CO689_RS01810 029fe580fc46efd10ba8c2949713decc 399 PIRSF PIRSF012509 1 398 1.9E-139 T 28-03-2018 IPR011426 CamS sex pheromone cAM373 CO689_RS01810 029fe580fc46efd10ba8c2949713decc 399 Gene3D G3DSA:3.10.570.10 39 398 1.9E-113 T 28-03-2018 CO689_RS04100 77b0d9f76add6c8540943b22ccb79466 589 SUPERFAMILY SSF55874 434 577 2.62E-15 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CO689_RS04100 77b0d9f76add6c8540943b22ccb79466 589 Pfam PF06580 Histidine kinase 378 457 6.1E-24 T 28-03-2018 IPR010559 Signal transduction histidine kinase, internal region GO:0000155|GO:0000160|GO:0016021 CO689_RS04100 77b0d9f76add6c8540943b22ccb79466 589 Gene3D G3DSA:3.30.450.40 218 388 5.6E-6 T 28-03-2018 IPR029016 GAF domain-like CO689_RS04100 77b0d9f76add6c8540943b22ccb79466 589 SMART SM00065 238 373 1.4E-4 T 28-03-2018 IPR003018 GAF domain GO:0005515 CO689_RS04100 77b0d9f76add6c8540943b22ccb79466 589 SUPERFAMILY SSF55781 247 364 4.21E-6 T 28-03-2018 IPR029016 GAF domain-like CO689_RS04100 77b0d9f76add6c8540943b22ccb79466 589 Pfam PF13492 GAF domain 247 364 2.6E-7 T 28-03-2018 IPR003018 GAF domain GO:0005515 CO689_RS04100 77b0d9f76add6c8540943b22ccb79466 589 Gene3D G3DSA:3.30.565.10 394 579 3.9E-19 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CO689_RS04100 77b0d9f76add6c8540943b22ccb79466 589 Pfam PF07694 5TMR of 5TMR-LYT 26 206 4.3E-46 T 28-03-2018 IPR011620 Signal transduction histidine kinase, 5TM receptor LytS, transmembrane region GO:0000155|GO:0000160|GO:0004673|GO:0016021|GO:0071555 CO689_RS04100 77b0d9f76add6c8540943b22ccb79466 589 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 476 578 2.0E-8 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CO689_RS03680 5ce72d97663a5845a078a138a95dab0b 299 SUPERFAMILY SSF52540 3 226 2.44E-59 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CO689_RS03680 5ce72d97663a5845a078a138a95dab0b 299 Pfam PF13732 Domain of unknown function (DUF4162) 212 294 1.6E-14 T 28-03-2018 IPR025302 Domain of unknown function DUF4162 CO689_RS03680 5ce72d97663a5845a078a138a95dab0b 299 Gene3D G3DSA:3.40.50.300 1 273 3.3E-61 T 28-03-2018 CO689_RS03680 5ce72d97663a5845a078a138a95dab0b 299 SMART SM00382 27 206 2.1E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain CO689_RS03680 5ce72d97663a5845a078a138a95dab0b 299 ProSitePatterns PS00211 ABC transporters family signature. 131 145 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CO689_RS03680 5ce72d97663a5845a078a138a95dab0b 299 Pfam PF00005 ABC transporter 19 158 7.1E-29 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CO689_RS09850 1192de857b8c4bbd5b2c3675b09abe4c 356 Pfam PF03060 Nitronate monooxygenase 7 347 6.6E-92 T 28-03-2018 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 CO689_RS09850 1192de857b8c4bbd5b2c3675b09abe4c 356 Gene3D G3DSA:3.20.20.70 3 353 1.6E-55 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CO689_RS09850 1192de857b8c4bbd5b2c3675b09abe4c 356 SUPERFAMILY SSF51412 102 349 1.83E-66 T 28-03-2018 CO689_RS09850 1192de857b8c4bbd5b2c3675b09abe4c 356 SUPERFAMILY SSF51412 4 75 1.83E-66 T 28-03-2018 CO689_RS02495 738b3821ba56dfbe98bcfda1280237d7 412 Pfam PF00464 Serine hydroxymethyltransferase 4 381 1.9E-180 T 28-03-2018 CO689_RS02495 738b3821ba56dfbe98bcfda1280237d7 412 Hamap MF_00051 Serine hydroxymethyltransferase [glyA]. 3 412 54.37 T 28-03-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0006545|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 CO689_RS02495 738b3821ba56dfbe98bcfda1280237d7 412 PIRSF PIRSF000412 1 409 1.3E-172 T 28-03-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0006545|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 CO689_RS02495 738b3821ba56dfbe98bcfda1280237d7 412 Gene3D G3DSA:3.40.640.10 33 269 5.1E-57 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CO689_RS02495 738b3821ba56dfbe98bcfda1280237d7 412 ProSitePatterns PS00096 Serine hydroxymethyltransferase pyridoxal-phosphate attachment site. 218 234 - T 28-03-2018 IPR019798 Serine hydroxymethyltransferase, pyridoxal phosphate binding site GO:0030170 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 CO689_RS02495 738b3821ba56dfbe98bcfda1280237d7 412 Gene3D G3DSA:3.90.1150.10 270 411 2.4E-62 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CO689_RS02495 738b3821ba56dfbe98bcfda1280237d7 412 SUPERFAMILY SSF53383 3 411 8.5E-184 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CO689_RS02255 abc9fa9c4a9cb6f89beb8b4ab7e5aae2 256 Gene3D G3DSA:1.10.10.10 7 33 0.12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS02255 abc9fa9c4a9cb6f89beb8b4ab7e5aae2 256 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 59 72 - T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CO689_RS02255 abc9fa9c4a9cb6f89beb8b4ab7e5aae2 256 SUPERFAMILY SSF88659 108 182 1.61E-15 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CO689_RS02255 abc9fa9c4a9cb6f89beb8b4ab7e5aae2 256 PRINTS PR00046 Major sigma-70 factor signature 59 72 7.1E-10 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CO689_RS02255 abc9fa9c4a9cb6f89beb8b4ab7e5aae2 256 PRINTS PR00046 Major sigma-70 factor signature 224 239 7.1E-10 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CO689_RS02255 abc9fa9c4a9cb6f89beb8b4ab7e5aae2 256 PRINTS PR00046 Major sigma-70 factor signature 207 219 7.1E-10 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CO689_RS02255 abc9fa9c4a9cb6f89beb8b4ab7e5aae2 256 PRINTS PR00046 Major sigma-70 factor signature 239 250 7.1E-10 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CO689_RS02255 abc9fa9c4a9cb6f89beb8b4ab7e5aae2 256 Gene3D G3DSA:1.10.1740.10 34 102 1.8E-20 T 28-03-2018 CO689_RS02255 abc9fa9c4a9cb6f89beb8b4ab7e5aae2 256 Pfam PF04539 Sigma-70 region 3 117 188 8.2E-18 T 28-03-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CO689_RS02255 abc9fa9c4a9cb6f89beb8b4ab7e5aae2 256 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 31 253 1.1E-37 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CO689_RS02255 abc9fa9c4a9cb6f89beb8b4ab7e5aae2 256 Gene3D G3DSA:1.10.10.10 106 158 1.1E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS02255 abc9fa9c4a9cb6f89beb8b4ab7e5aae2 256 SUPERFAMILY SSF88659 181 254 7.29E-16 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CO689_RS02255 abc9fa9c4a9cb6f89beb8b4ab7e5aae2 256 SUPERFAMILY SSF88946 12 104 1.57E-25 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CO689_RS02255 abc9fa9c4a9cb6f89beb8b4ab7e5aae2 256 Pfam PF04542 Sigma-70 region 2 35 104 1.4E-16 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CO689_RS02255 abc9fa9c4a9cb6f89beb8b4ab7e5aae2 256 TIGRFAM TIGR02941 Sigma_B: RNA polymerase sigma-B factor 3 255 1.2E-139 T 28-03-2018 IPR014288 RNA polymerase sigma-B factor GO:0016987 CO689_RS02255 abc9fa9c4a9cb6f89beb8b4ab7e5aae2 256 Gene3D G3DSA:1.10.10.10 182 256 6.1E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS02255 abc9fa9c4a9cb6f89beb8b4ab7e5aae2 256 Pfam PF04545 Sigma-70, region 4 205 251 1.7E-15 T 28-03-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CO689_RS02255 abc9fa9c4a9cb6f89beb8b4ab7e5aae2 256 TIGRFAM TIGR02980 SigBFG: RNA polymerase sigma-70 factor, sigma-B/F/G subfamily 29 254 2.5E-90 T 28-03-2018 IPR014322 RNA polymerase sigma-B/F/G type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CO689_RS02255 abc9fa9c4a9cb6f89beb8b4ab7e5aae2 256 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 224 250 - T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CO689_RS12975 ab459038e55027cdb890bd31a977b596 352 PIRSF PIRSF036458 1 352 3.9E-128 T 28-03-2018 IPR011245 Butyrate kinase GO:0005524|GO:0005737|GO:0016310|GO:0047761 KEGG: 00650+2.7.2.7 CO689_RS12975 ab459038e55027cdb890bd31a977b596 352 Gene3D G3DSA:3.30.420.40 176 351 6.1E-40 T 28-03-2018 CO689_RS12975 ab459038e55027cdb890bd31a977b596 352 ProSitePatterns PS01076 Acetate and butyrate kinases family signature 2. 176 193 - T 28-03-2018 IPR023865 Aliphatic acid kinase, short-chain, conserved site GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CO689_RS12975 ab459038e55027cdb890bd31a977b596 352 SUPERFAMILY SSF53067 2 169 1.14E-55 T 28-03-2018 CO689_RS12975 ab459038e55027cdb890bd31a977b596 352 SUPERFAMILY SSF53067 116 341 2.69E-46 T 28-03-2018 CO689_RS12975 ab459038e55027cdb890bd31a977b596 352 ProSitePatterns PS01075 Acetate and butyrate kinases family signature 1. 4 15 - T 28-03-2018 IPR023865 Aliphatic acid kinase, short-chain, conserved site GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CO689_RS12975 ab459038e55027cdb890bd31a977b596 352 Hamap MF_00542 Probable butyrate kinase [buk]. 1 352 120.246 T 28-03-2018 IPR011245 Butyrate kinase GO:0005524|GO:0005737|GO:0016310|GO:0047761 KEGG: 00650+2.7.2.7 CO689_RS12975 ab459038e55027cdb890bd31a977b596 352 TIGRFAM TIGR02707 butyr_kinase: butyrate kinase 4 349 1.3E-123 T 28-03-2018 IPR011245 Butyrate kinase GO:0005524|GO:0005737|GO:0016310|GO:0047761 KEGG: 00650+2.7.2.7 CO689_RS12975 ab459038e55027cdb890bd31a977b596 352 Pfam PF00871 Acetokinase family 4 328 1.2E-55 T 28-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CO689_RS12975 ab459038e55027cdb890bd31a977b596 352 Gene3D G3DSA:3.30.420.40 1 175 7.5E-49 T 28-03-2018 CO689_RS12975 ab459038e55027cdb890bd31a977b596 352 PRINTS PR00471 Acetate kinase family signature 176 197 1.1E-15 T 28-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CO689_RS12975 ab459038e55027cdb890bd31a977b596 352 PRINTS PR00471 Acetate kinase family signature 270 283 1.1E-15 T 28-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CO689_RS12975 ab459038e55027cdb890bd31a977b596 352 PRINTS PR00471 Acetate kinase family signature 293 309 1.1E-15 T 28-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CO689_RS12975 ab459038e55027cdb890bd31a977b596 352 PRINTS PR00471 Acetate kinase family signature 4 15 1.1E-15 T 28-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CO689_RS11900 584a10c4c61b164a934e69417032b9ab 172 Pfam PF06769 YoeB-like toxin of bacterial type II toxin-antitoxin system 88 170 9.0E-8 T 28-03-2018 IPR009614 Toxin YoeB GO:0004519|GO:0006401 CO689_RS11900 584a10c4c61b164a934e69417032b9ab 172 Gene3D G3DSA:3.30.2310.20 85 171 3.1E-4 T 28-03-2018 CO689_RS05615 d205a31074be419b8df87efe80dc9f29 334 TIGRFAM TIGR00658 orni_carb_tr: ornithine carbamoyltransferase 7 330 9.5E-125 T 28-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CO689_RS05615 d205a31074be419b8df87efe80dc9f29 334 Gene3D G3DSA:3.40.50.1370 5 164 3.0E-53 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CO689_RS05615 d205a31074be419b8df87efe80dc9f29 334 PRINTS PR00102 Ornithine carbamoyltransferase signature 50 64 5.7E-30 T 28-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CO689_RS05615 d205a31074be419b8df87efe80dc9f29 334 PRINTS PR00102 Ornithine carbamoyltransferase signature 228 238 5.7E-30 T 28-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CO689_RS05615 d205a31074be419b8df87efe80dc9f29 334 PRINTS PR00102 Ornithine carbamoyltransferase signature 83 96 5.7E-30 T 28-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CO689_RS05615 d205a31074be419b8df87efe80dc9f29 334 PRINTS PR00102 Ornithine carbamoyltransferase signature 123 137 5.7E-30 T 28-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CO689_RS05615 d205a31074be419b8df87efe80dc9f29 334 PRINTS PR00102 Ornithine carbamoyltransferase signature 309 320 5.7E-30 T 28-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CO689_RS05615 d205a31074be419b8df87efe80dc9f29 334 SUPERFAMILY SSF53671 1 332 1.44E-99 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CO689_RS05615 d205a31074be419b8df87efe80dc9f29 334 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 7 147 4.8E-45 T 28-03-2018 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 CO689_RS05615 d205a31074be419b8df87efe80dc9f29 334 Gene3D G3DSA:3.40.50.1370 165 332 1.1E-49 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CO689_RS05615 d205a31074be419b8df87efe80dc9f29 334 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 155 328 2.2E-55 T 28-03-2018 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 CO689_RS05615 d205a31074be419b8df87efe80dc9f29 334 Hamap MF_01109 Ornithine carbamoyltransferase, catabolic [argI]. 6 331 81.187 T 28-03-2018 IPR024904 Ornithine carbamoyltransferase GO:0004585|GO:0006591 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400 CO689_RS05615 d205a31074be419b8df87efe80dc9f29 334 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 52 59 - T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CO689_RS05615 d205a31074be419b8df87efe80dc9f29 334 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 134 145 2.1E-24 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CO689_RS05615 d205a31074be419b8df87efe80dc9f29 334 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 266 275 2.1E-24 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CO689_RS05615 d205a31074be419b8df87efe80dc9f29 334 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 52 71 2.1E-24 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CO689_RS05615 d205a31074be419b8df87efe80dc9f29 334 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 295 318 2.1E-24 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CO689_RS11335 4df3abd78546d722ebd3cf8e5d876a81 302 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 43 50 - T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CO689_RS11335 4df3abd78546d722ebd3cf8e5d876a81 302 PRINTS PR00101 Aspartate carbamoyltransferase signature 33 55 2.9E-31 T 28-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CO689_RS11335 4df3abd78546d722ebd3cf8e5d876a81 302 PRINTS PR00101 Aspartate carbamoyltransferase signature 125 142 2.9E-31 T 28-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CO689_RS11335 4df3abd78546d722ebd3cf8e5d876a81 302 PRINTS PR00101 Aspartate carbamoyltransferase signature 71 80 2.9E-31 T 28-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CO689_RS11335 4df3abd78546d722ebd3cf8e5d876a81 302 PRINTS PR00101 Aspartate carbamoyltransferase signature 205 214 2.9E-31 T 28-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CO689_RS11335 4df3abd78546d722ebd3cf8e5d876a81 302 PRINTS PR00101 Aspartate carbamoyltransferase signature 246 251 2.9E-31 T 28-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CO689_RS11335 4df3abd78546d722ebd3cf8e5d876a81 302 PRINTS PR00101 Aspartate carbamoyltransferase signature 270 284 2.9E-31 T 28-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CO689_RS11335 4df3abd78546d722ebd3cf8e5d876a81 302 SUPERFAMILY SSF53671 1 289 1.7E-92 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CO689_RS11335 4df3abd78546d722ebd3cf8e5d876a81 302 TIGRFAM TIGR00670 asp_carb_tr: aspartate carbamoyltransferase 2 289 5.1E-94 T 28-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CO689_RS11335 4df3abd78546d722ebd3cf8e5d876a81 302 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 2 139 9.6E-43 T 28-03-2018 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 CO689_RS11335 4df3abd78546d722ebd3cf8e5d876a81 302 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 254 277 8.4E-24 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CO689_RS11335 4df3abd78546d722ebd3cf8e5d876a81 302 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 242 251 8.4E-24 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CO689_RS11335 4df3abd78546d722ebd3cf8e5d876a81 302 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 43 62 8.4E-24 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CO689_RS11335 4df3abd78546d722ebd3cf8e5d876a81 302 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 126 137 8.4E-24 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CO689_RS11335 4df3abd78546d722ebd3cf8e5d876a81 302 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 145 286 2.4E-21 T 28-03-2018 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 CO689_RS11335 4df3abd78546d722ebd3cf8e5d876a81 302 Hamap MF_00001 Aspartate carbamoyltransferase [pyrB]. 1 291 39.402 T 28-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CO689_RS11335 4df3abd78546d722ebd3cf8e5d876a81 302 Gene3D G3DSA:3.40.50.1370 140 295 4.3E-48 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CO689_RS11335 4df3abd78546d722ebd3cf8e5d876a81 302 Gene3D G3DSA:3.40.50.1370 1 139 5.7E-49 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CO689_RS02990 4802d69fd9cf490d1c8e9cfcc8ea6134 145 Hamap MF_01366 50S ribosomal protein L13 [rplM]. 16 144 27.286 T 28-03-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 CO689_RS02990 4802d69fd9cf490d1c8e9cfcc8ea6134 145 ProSitePatterns PS00783 Ribosomal protein L13 signature. 106 128 - T 28-03-2018 IPR023563 Ribosomal protein L13, conserved site GO:0003735|GO:0005840|GO:0006412 CO689_RS02990 4802d69fd9cf490d1c8e9cfcc8ea6134 145 PIRSF PIRSF002181 1 143 8.8E-50 T 28-03-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 CO689_RS02990 4802d69fd9cf490d1c8e9cfcc8ea6134 145 TIGRFAM TIGR01066 rplM_bact: ribosomal protein uL13 4 142 2.7E-61 T 28-03-2018 IPR005823 Ribosomal protein L13, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CO689_RS02990 4802d69fd9cf490d1c8e9cfcc8ea6134 145 SUPERFAMILY SSF52161 5 143 3.14E-56 T 28-03-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 CO689_RS02990 4802d69fd9cf490d1c8e9cfcc8ea6134 145 Gene3D G3DSA:3.90.1180.10 1 145 7.4E-60 T 28-03-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 CO689_RS02990 4802d69fd9cf490d1c8e9cfcc8ea6134 145 Pfam PF00572 Ribosomal protein L13 15 139 7.3E-54 T 28-03-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 CO689_RS07390 8d6c624250411df37806a3dbe2bf575d 241 Pfam PF12146 Serine aminopeptidase, S33 17 106 7.0E-10 T 28-03-2018 IPR022742 Serine aminopeptidase, S33 CO689_RS07390 8d6c624250411df37806a3dbe2bf575d 241 SUPERFAMILY SSF53474 171 241 3.0E-33 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CO689_RS07390 8d6c624250411df37806a3dbe2bf575d 241 SUPERFAMILY SSF53474 15 121 3.0E-33 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CO689_RS07390 8d6c624250411df37806a3dbe2bf575d 241 Gene3D G3DSA:3.40.50.1820 1 241 9.9E-33 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CO689_RS07390 8d6c624250411df37806a3dbe2bf575d 241 PIRSF PIRSF017388 2 241 2.2E-64 T 28-03-2018 IPR012354 Esterase/lipase GO:0052689 CO689_RS09420 17287774d65b25c0ea91136e186067ae 67 Gene3D G3DSA:1.10.150.260 1 67 2.8E-21 T 28-03-2018 IPR023089 YozE SAM-like domain CO689_RS09420 17287774d65b25c0ea91136e186067ae 67 SUPERFAMILY SSF140652 1 66 3.14E-22 T 28-03-2018 IPR023089 YozE SAM-like domain CO689_RS09420 17287774d65b25c0ea91136e186067ae 67 Pfam PF06855 YozE SAM-like fold 2 65 1.3E-20 T 28-03-2018 IPR023089 YozE SAM-like domain CO689_RS04155 a1155cf8df8ab602dfa6708f7e846285 404 SMART SM00116 317 365 0.003 T 28-03-2018 IPR000644 CBS domain CO689_RS04155 a1155cf8df8ab602dfa6708f7e846285 404 SMART SM00116 257 305 9.1E-6 T 28-03-2018 IPR000644 CBS domain CO689_RS04155 a1155cf8df8ab602dfa6708f7e846285 404 SUPERFAMILY SSF52540 1 240 2.89E-76 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CO689_RS04155 a1155cf8df8ab602dfa6708f7e846285 404 TIGRFAM TIGR01186 proV: glycine betaine/L-proline transport ATP binding subunit 13 370 1.8E-138 T 28-03-2018 IPR005892 Glycine betaine transport ATP-binding subunit GO:0005524|GO:0016020|GO:0031460 CO689_RS04155 a1155cf8df8ab602dfa6708f7e846285 404 SMART SM00382 27 213 2.2E-15 T 28-03-2018 IPR003593 AAA+ ATPase domain CO689_RS04155 a1155cf8df8ab602dfa6708f7e846285 404 Gene3D G3DSA:3.10.580.10 253 382 8.2E-25 T 28-03-2018 CO689_RS04155 a1155cf8df8ab602dfa6708f7e846285 404 Pfam PF00571 CBS domain 314 362 2.5E-7 T 28-03-2018 IPR000644 CBS domain CO689_RS04155 a1155cf8df8ab602dfa6708f7e846285 404 Pfam PF00571 CBS domain 251 300 3.5E-6 T 28-03-2018 IPR000644 CBS domain CO689_RS04155 a1155cf8df8ab602dfa6708f7e846285 404 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CO689_RS04155 a1155cf8df8ab602dfa6708f7e846285 404 SUPERFAMILY SSF54631 250 372 1.33E-23 T 28-03-2018 CO689_RS04155 a1155cf8df8ab602dfa6708f7e846285 404 Gene3D G3DSA:3.40.50.300 1 252 9.2E-79 T 28-03-2018 CO689_RS04155 a1155cf8df8ab602dfa6708f7e846285 404 Pfam PF00005 ABC transporter 19 163 3.9E-34 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CO689_RS02670 d905b53fab898bbe4e8a7ccc72b6bea7 220 Gene3D G3DSA:3.40.50.720 2 216 3.1E-34 T 28-03-2018 CO689_RS02670 d905b53fab898bbe4e8a7ccc72b6bea7 220 Pfam PF13460 NAD(P)H-binding 7 192 2.9E-44 T 28-03-2018 IPR016040 NAD(P)-binding domain CO689_RS02670 d905b53fab898bbe4e8a7ccc72b6bea7 220 SUPERFAMILY SSF51735 3 206 6.07E-39 T 28-03-2018 IPR016040 NAD(P)-binding domain CO689_RS05645 9f0bc1f10feec09127ac8ca69c4b2e2e 450 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 331 439 7.4E-26 T 28-03-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 CO689_RS05645 9f0bc1f10feec09127ac8ca69c4b2e2e 450 SUPERFAMILY SSF55424 329 449 1.89E-29 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CO689_RS05645 9f0bc1f10feec09127ac8ca69c4b2e2e 450 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 4 311 6.3E-70 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CO689_RS05645 9f0bc1f10feec09127ac8ca69c4b2e2e 450 Gene3D G3DSA:3.40.50.720 1 36 0.016 T 28-03-2018 CO689_RS05645 9f0bc1f10feec09127ac8ca69c4b2e2e 450 Gene3D G3DSA:3.50.50.60 237 276 0.14 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CO689_RS05645 9f0bc1f10feec09127ac8ca69c4b2e2e 450 Gene3D G3DSA:3.50.50.60 109 236 1.3E-27 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CO689_RS05645 9f0bc1f10feec09127ac8ca69c4b2e2e 450 Gene3D G3DSA:1.10.287.990 37 103 9.9E-19 T 28-03-2018 CO689_RS05645 9f0bc1f10feec09127ac8ca69c4b2e2e 450 SUPERFAMILY SSF51905 3 321 2.52E-57 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CO689_RS05645 9f0bc1f10feec09127ac8ca69c4b2e2e 450 TIGRFAM TIGR01350 lipoamide_DH: dihydrolipoyl dehydrogenase 3 449 5.3E-148 T 28-03-2018 IPR006258 Dihydrolipoamide dehydrogenase GO:0004148|GO:0050660|GO:0055114 KEGG: 00010+1.8.1.4|KEGG: 00020+1.8.1.4|KEGG: 00260+1.8.1.4|KEGG: 00280+1.8.1.4|KEGG: 00620+1.8.1.4|KEGG: 00640+1.8.1.4|MetaCyc: PWY-5046|MetaCyc: PWY-5084|Reactome: R-HSA-204174|Reactome: R-HSA-389661|Reactome: R-HSA-5362517|Reactome: R-HSA-6783984|Reactome: R-HSA-70268|Reactome: R-HSA-70895|Reactome: R-HSA-71064|Reactome: R-HSA-71403 CO689_RS05645 9f0bc1f10feec09127ac8ca69c4b2e2e 450 PIRSF PIRSF000350 1 446 8.8E-89 T 28-03-2018 CO689_RS05645 9f0bc1f10feec09127ac8ca69c4b2e2e 450 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 392 407 1.7E-63 T 28-03-2018 CO689_RS05645 9f0bc1f10feec09127ac8ca69c4b2e2e 450 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 414 434 1.7E-63 T 28-03-2018 CO689_RS05645 9f0bc1f10feec09127ac8ca69c4b2e2e 450 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 5 27 1.7E-63 T 28-03-2018 CO689_RS05645 9f0bc1f10feec09127ac8ca69c4b2e2e 450 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 250 264 1.7E-63 T 28-03-2018 CO689_RS05645 9f0bc1f10feec09127ac8ca69c4b2e2e 450 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 169 194 1.7E-63 T 28-03-2018 CO689_RS05645 9f0bc1f10feec09127ac8ca69c4b2e2e 450 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 133 142 1.7E-63 T 28-03-2018 CO689_RS05645 9f0bc1f10feec09127ac8ca69c4b2e2e 450 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 291 298 1.7E-63 T 28-03-2018 CO689_RS05645 9f0bc1f10feec09127ac8ca69c4b2e2e 450 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 327 348 1.7E-63 T 28-03-2018 CO689_RS05645 9f0bc1f10feec09127ac8ca69c4b2e2e 450 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 37 52 1.7E-63 T 28-03-2018 CO689_RS05645 9f0bc1f10feec09127ac8ca69c4b2e2e 450 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 169 187 7.1E-38 T 28-03-2018 CO689_RS05645 9f0bc1f10feec09127ac8ca69c4b2e2e 450 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 130 148 7.1E-38 T 28-03-2018 CO689_RS05645 9f0bc1f10feec09127ac8ca69c4b2e2e 450 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 249 265 7.1E-38 T 28-03-2018 CO689_RS05645 9f0bc1f10feec09127ac8ca69c4b2e2e 450 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 7.1E-38 T 28-03-2018 CO689_RS05645 9f0bc1f10feec09127ac8ca69c4b2e2e 450 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 276 298 7.1E-38 T 28-03-2018 CO689_RS05645 9f0bc1f10feec09127ac8ca69c4b2e2e 450 Gene3D G3DSA:3.30.390.30 329 450 1.8E-30 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CO689_RS05645 9f0bc1f10feec09127ac8ca69c4b2e2e 450 Gene3D G3DSA:3.50.50.60 277 319 0.067 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CO689_RS05645 9f0bc1f10feec09127ac8ca69c4b2e2e 450 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 38 48 - T 28-03-2018 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 CO689_RS06095 8d4079d8bc2485ec77617d8aec5d24e0 159 Pfam PF03830 PTS system sorbose subfamily IIB component 4 149 1.1E-47 T 28-03-2018 IPR004720 Phosphotransferase system, sorbose subfamily IIB component GO:0005737|GO:0008982|GO:0009401 CO689_RS06095 8d4079d8bc2485ec77617d8aec5d24e0 159 Gene3D G3DSA:3.40.35.10 2 158 2.2E-51 T 28-03-2018 IPR004720 Phosphotransferase system, sorbose subfamily IIB component GO:0005737|GO:0008982|GO:0009401 CO689_RS06095 8d4079d8bc2485ec77617d8aec5d24e0 159 SUPERFAMILY SSF52728 2 158 2.22E-50 T 28-03-2018 IPR004720 Phosphotransferase system, sorbose subfamily IIB component GO:0005737|GO:0008982|GO:0009401 CO689_RS04330 30c4c7a9dec9f22997ef375a9757acde 587 Gene3D G3DSA:1.20.1560.10 10 336 3.5E-73 T 28-03-2018 CO689_RS04330 30c4c7a9dec9f22997ef375a9757acde 587 ProSitePatterns PS00211 ABC transporters family signature. 487 501 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CO689_RS04330 30c4c7a9dec9f22997ef375a9757acde 587 Pfam PF00664 ABC transporter transmembrane region 31 303 6.4E-43 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CO689_RS04330 30c4c7a9dec9f22997ef375a9757acde 587 SUPERFAMILY SSF52540 341 585 2.72E-82 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CO689_RS04330 30c4c7a9dec9f22997ef375a9757acde 587 SUPERFAMILY SSF90123 18 330 9.55E-76 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CO689_RS04330 30c4c7a9dec9f22997ef375a9757acde 587 SMART SM00382 375 567 3.2E-16 T 28-03-2018 IPR003593 AAA+ ATPase domain CO689_RS04330 30c4c7a9dec9f22997ef375a9757acde 587 Pfam PF00005 ABC transporter 366 515 9.2E-32 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CO689_RS04330 30c4c7a9dec9f22997ef375a9757acde 587 Gene3D G3DSA:3.40.50.300 337 587 7.4E-72 T 28-03-2018 CO689_RS05690 baf644662f5639b992bc4bbfb13bfed9 277 Pfam PF11299 Protein of unknown function (DUF3100) 22 253 5.7E-88 T 28-03-2018 IPR021450 Protein of unknown function DUF3100 CO689_RS09280 0e92f1d93dc534023d9f49dec9ff4fbf 547 Pfam PF03354 Phage Terminase 75 532 3.1E-75 T 28-03-2018 IPR005021 Terminase large subunit, Lambdalikevirus-type CO689_RS09280 0e92f1d93dc534023d9f49dec9ff4fbf 547 Gene3D G3DSA:3.40.50.300 70 248 7.0E-4 T 28-03-2018 CO689_RS02665 9aa53f6c751435870c08c0f1793ffce5 232 Gene3D G3DSA:1.10.10.10 2 73 3.0E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS02665 9aa53f6c751435870c08c0f1793ffce5 232 SMART SM00895 93 220 1.9E-21 T 28-03-2018 IPR011711 GntR, C-terminal CO689_RS02665 9aa53f6c751435870c08c0f1793ffce5 232 Gene3D G3DSA:1.20.120.530 86 232 7.3E-32 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CO689_RS02665 9aa53f6c751435870c08c0f1793ffce5 232 SUPERFAMILY SSF46785 4 75 4.57E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS02665 9aa53f6c751435870c08c0f1793ffce5 232 SMART SM00345 12 71 2.2E-18 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CO689_RS02665 9aa53f6c751435870c08c0f1793ffce5 232 SUPERFAMILY SSF48008 89 228 1.6E-29 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CO689_RS02665 9aa53f6c751435870c08c0f1793ffce5 232 Pfam PF00392 Bacterial regulatory proteins, gntR family 9 71 1.4E-19 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CO689_RS02665 9aa53f6c751435870c08c0f1793ffce5 232 Pfam PF07729 FCD domain 93 219 1.9E-26 T 28-03-2018 IPR011711 GntR, C-terminal CO689_RS08075 eb9f78ebc4c97129b07944b84bf140c2 395 Pfam PF03143 Elongation factor Tu C-terminal domain 299 393 2.1E-34 T 28-03-2018 IPR004160 Translation elongation factor EFTu/EF1A, C-terminal CO689_RS08075 eb9f78ebc4c97129b07944b84bf140c2 395 Gene3D G3DSA:3.40.50.300 75 193 1.8E-30 T 28-03-2018 CO689_RS08075 eb9f78ebc4c97129b07944b84bf140c2 395 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 12 146 1.0E-13 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 CO689_RS08075 eb9f78ebc4c97129b07944b84bf140c2 395 Pfam PF03144 Elongation factor Tu domain 2 225 294 1.8E-18 T 28-03-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 CO689_RS08075 eb9f78ebc4c97129b07944b84bf140c2 395 PRINTS PR00315 GTP-binding elongation factor signature 131 140 2.4E-24 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CO689_RS08075 eb9f78ebc4c97129b07944b84bf140c2 395 PRINTS PR00315 GTP-binding elongation factor signature 94 105 2.4E-24 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CO689_RS08075 eb9f78ebc4c97129b07944b84bf140c2 395 PRINTS PR00315 GTP-binding elongation factor signature 58 66 2.4E-24 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CO689_RS08075 eb9f78ebc4c97129b07944b84bf140c2 395 PRINTS PR00315 GTP-binding elongation factor signature 78 88 2.4E-24 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CO689_RS08075 eb9f78ebc4c97129b07944b84bf140c2 395 PRINTS PR00315 GTP-binding elongation factor signature 14 27 2.4E-24 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CO689_RS08075 eb9f78ebc4c97129b07944b84bf140c2 395 TIGRFAM TIGR00485 EF-Tu: translation elongation factor Tu 1 393 1.7E-231 T 28-03-2018 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CO689_RS08075 eb9f78ebc4c97129b07944b84bf140c2 395 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 51 66 - T 28-03-2018 IPR031157 Tr-type G domain, conserved site CO689_RS08075 eb9f78ebc4c97129b07944b84bf140c2 395 Gene3D G3DSA:2.40.30.10 301 394 3.0E-32 T 28-03-2018 CO689_RS08075 eb9f78ebc4c97129b07944b84bf140c2 395 Hamap MF_00118_B Elongation factor Tu [tuf]. 1 395 59.967 T 28-03-2018 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CO689_RS08075 eb9f78ebc4c97129b07944b84bf140c2 395 SUPERFAMILY SSF50465 303 394 1.27E-36 T 28-03-2018 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal CO689_RS08075 eb9f78ebc4c97129b07944b84bf140c2 395 SUPERFAMILY SSF52540 6 219 5.95E-61 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CO689_RS08075 eb9f78ebc4c97129b07944b84bf140c2 395 Pfam PF00009 Elongation factor Tu GTP binding domain 10 201 6.7E-60 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CO689_RS08075 eb9f78ebc4c97129b07944b84bf140c2 395 SUPERFAMILY SSF50447 203 302 6.48E-32 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain CO689_RS08075 eb9f78ebc4c97129b07944b84bf140c2 395 Gene3D G3DSA:2.40.30.10 194 299 1.2E-32 T 28-03-2018 CO689_RS08075 eb9f78ebc4c97129b07944b84bf140c2 395 Gene3D G3DSA:3.40.50.300 1 74 1.2E-11 T 28-03-2018 CO689_RS08830 9f1f18ddd5b9546718fbd10c909a7343 647 SUPERFAMILY SSF52794 176 272 1.67E-35 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 CO689_RS08830 9f1f18ddd5b9546718fbd10c909a7343 647 SUPERFAMILY SSF55804 1 147 8.5E-44 T 28-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 CO689_RS08830 9f1f18ddd5b9546718fbd10c909a7343 647 ProSitePatterns PS00372 PTS EIIA domains phosphorylation site signature 2. 52 68 - T 28-03-2018 IPR002178 PTS EIIA type-2 domain CO689_RS08830 9f1f18ddd5b9546718fbd10c909a7343 647 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 179 267 3.1E-17 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 CO689_RS08830 9f1f18ddd5b9546718fbd10c909a7343 647 TIGRFAM TIGR00829 FRU: PTS system, Fru family, IIB component 177 260 3.7E-32 T 28-03-2018 IPR003353 Phosphotransferase system, fructose-specific IIB subunit GO:0009401|GO:0022877 KEGG: 00051+2.7.1.202|KEGG: 00230+2.7.1.20|MetaCyc: PWY-6619 CO689_RS08830 9f1f18ddd5b9546718fbd10c909a7343 647 Pfam PF02378 Phosphotransferase system, EIIC 307 576 1.6E-18 T 28-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 CO689_RS08830 9f1f18ddd5b9546718fbd10c909a7343 647 TIGRFAM TIGR01427 PTS_IIC_fructo: PTS system, Fru family, IIC component 290 631 1.7E-117 T 28-03-2018 IPR006327 Phosphotransferase system, fructose IIC component GO:0005351|GO:0008982|GO:0009401|GO:0016021 CO689_RS08830 9f1f18ddd5b9546718fbd10c909a7343 647 TIGRFAM TIGR00848 fruA: PTS system, fructose subfamily, IIA component 7 133 2.8E-39 T 28-03-2018 IPR004715 Phosphotransferase system, IIA component fructose subfamily GO:0008982|GO:0009401|GO:0016021 CO689_RS08830 9f1f18ddd5b9546718fbd10c909a7343 647 Gene3D G3DSA:3.40.930.10 1 162 3.5E-46 T 28-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 CO689_RS08830 9f1f18ddd5b9546718fbd10c909a7343 647 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 5 147 7.4E-42 T 28-03-2018 IPR002178 PTS EIIA type-2 domain CO689_RS08830 9f1f18ddd5b9546718fbd10c909a7343 647 Gene3D G3DSA:3.40.50.2300 175 271 9.2E-39 T 28-03-2018 CO689_RS07025 5782b342a65bccc45777105b4c6e074c 454 ProSitePatterns PS01008 DnaA protein signature. 411 430 - T 28-03-2018 IPR018312 Chromosomal replication control, initiator DnaA, conserved site GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 CO689_RS07025 5782b342a65bccc45777105b4c6e074c 454 Pfam PF11638 DnaA N-terminal domain 4 68 2.2E-10 T 28-03-2018 IPR024633 DnaA N-terminal domain CO689_RS07025 5782b342a65bccc45777105b4c6e074c 454 SUPERFAMILY SSF48295 348 453 6.28E-37 T 28-03-2018 IPR010921 Trp repressor/replication initiator GO:0043565 CO689_RS07025 5782b342a65bccc45777105b4c6e074c 454 TIGRFAM TIGR00362 DnaA: chromosomal replication initiator protein DnaA 7 451 8.1E-179 T 28-03-2018 IPR001957 Chromosomal replication control, initiator DnaA GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 CO689_RS07025 5782b342a65bccc45777105b4c6e074c 454 SMART SM00382 149 280 2.7E-9 T 28-03-2018 IPR003593 AAA+ ATPase domain CO689_RS07025 5782b342a65bccc45777105b4c6e074c 454 Pfam PF00308 Bacterial dnaA protein 118 334 8.6E-103 T 28-03-2018 IPR013317 Chromosomal replication initiator protein DnaA CO689_RS07025 5782b342a65bccc45777105b4c6e074c 454 Hamap MF_00377 Chromosomal replication initiator protein DnaA [dnaA]. 4 452 33.927 T 28-03-2018 IPR001957 Chromosomal replication control, initiator DnaA GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 CO689_RS07025 5782b342a65bccc45777105b4c6e074c 454 Gene3D G3DSA:1.10.1750.10 355 452 4.1E-37 T 28-03-2018 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 CO689_RS07025 5782b342a65bccc45777105b4c6e074c 454 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 182 196 1.8E-52 T 28-03-2018 IPR020591 Chromosomal replication control, initiator DnaA-like CO689_RS07025 5782b342a65bccc45777105b4c6e074c 454 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 150 170 1.8E-52 T 28-03-2018 IPR020591 Chromosomal replication control, initiator DnaA-like CO689_RS07025 5782b342a65bccc45777105b4c6e074c 454 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 248 275 1.8E-52 T 28-03-2018 IPR020591 Chromosomal replication control, initiator DnaA-like CO689_RS07025 5782b342a65bccc45777105b4c6e074c 454 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 214 228 1.8E-52 T 28-03-2018 IPR020591 Chromosomal replication control, initiator DnaA-like CO689_RS07025 5782b342a65bccc45777105b4c6e074c 454 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 411 430 1.8E-52 T 28-03-2018 IPR020591 Chromosomal replication control, initiator DnaA-like CO689_RS07025 5782b342a65bccc45777105b4c6e074c 454 Gene3D G3DSA:3.40.50.300 114 281 7.1E-22 T 28-03-2018 CO689_RS07025 5782b342a65bccc45777105b4c6e074c 454 Gene3D G3DSA:1.10.8.60 283 354 1.2E-29 T 28-03-2018 CO689_RS07025 5782b342a65bccc45777105b4c6e074c 454 SUPERFAMILY SSF52540 117 328 1.11E-45 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CO689_RS07025 5782b342a65bccc45777105b4c6e074c 454 Pfam PF08299 Bacterial dnaA protein helix-turn-helix 362 430 8.6E-31 T 28-03-2018 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 CO689_RS07025 5782b342a65bccc45777105b4c6e074c 454 SMART SM00760 361 430 1.7E-41 T 28-03-2018 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 CO689_RS10990 4c45d64e7171e6929172559f02ce7b9d 146 SUPERFAMILY SSF158622 4 125 1.31E-32 T 28-03-2018 IPR023378 YheA/YmcA-like domain CO689_RS10990 4c45d64e7171e6929172559f02ce7b9d 146 Gene3D G3DSA:1.20.1500.10 8 117 1.3E-27 T 28-03-2018 IPR023378 YheA/YmcA-like domain CO689_RS10990 4c45d64e7171e6929172559f02ce7b9d 146 Pfam PF06133 Control of competence regulator ComK, YlbF/YmcA 10 115 8.2E-20 T 28-03-2018 IPR010368 Control of competence regulator ComK, YlbF/YmcA CO689_RS05635 84962c16de0d4845fabd9fb4feea2979 112 Gene3D G3DSA:1.10.287.1080 1 95 5.4E-20 T 28-03-2018 CO689_RS05635 84962c16de0d4845fabd9fb4feea2979 112 Pfam PF12643 MazG-like family 31 112 2.5E-24 T 28-03-2018 IPR025984 dCTP pyrophosphatase 1 GO:0009143|GO:0047429 KEGG: 00240+3.6.1.12|Reactome: R-HSA-499943 CO689_RS05635 84962c16de0d4845fabd9fb4feea2979 112 SUPERFAMILY SSF101386 6 111 3.2E-34 T 28-03-2018 CO689_RS05635 84962c16de0d4845fabd9fb4feea2979 112 PIRSF PIRSF029826 1 112 7.4E-39 T 28-03-2018 IPR025984 dCTP pyrophosphatase 1 GO:0009143|GO:0047429 KEGG: 00240+3.6.1.12|Reactome: R-HSA-499943 CO689_RS01325 f9787d6d4341aed3a165b71cfc86b11d 346 Gene3D G3DSA:3.20.20.210 4 345 2.6E-91 T 28-03-2018 CO689_RS01325 f9787d6d4341aed3a165b71cfc86b11d 346 SUPERFAMILY SSF51726 5 344 2.49E-99 T 28-03-2018 CO689_RS01325 f9787d6d4341aed3a165b71cfc86b11d 346 Pfam PF01208 Uroporphyrinogen decarboxylase (URO-D) 5 342 1.9E-118 T 28-03-2018 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 CO689_RS01325 f9787d6d4341aed3a165b71cfc86b11d 346 Hamap MF_00218 Uroporphyrinogen decarboxylase [hemE]. 6 343 45.293 T 28-03-2018 IPR006361 Uroporphyrinogen decarboxylase HemE GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 CO689_RS01325 f9787d6d4341aed3a165b71cfc86b11d 346 ProSitePatterns PS00906 Uroporphyrinogen decarboxylase signature 1. 22 31 - T 28-03-2018 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 CO689_RS01325 f9787d6d4341aed3a165b71cfc86b11d 346 ProSitePatterns PS00907 Uroporphyrinogen decarboxylase signature 2. 140 156 - T 28-03-2018 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 CO689_RS01325 f9787d6d4341aed3a165b71cfc86b11d 346 TIGRFAM TIGR01464 hemE: uroporphyrinogen decarboxylase 9 341 1.5E-123 T 28-03-2018 IPR006361 Uroporphyrinogen decarboxylase HemE GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 CO689_RS12620 56c9d609b49b9cde5e7b8c86e4e4732c 317 SUPERFAMILY SSF55831 4 317 1.28E-129 T 28-03-2018 IPR023451 Thymidylate synthase/dCMP hydroxymethylase domain KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 CO689_RS12620 56c9d609b49b9cde5e7b8c86e4e4732c 317 ProSitePatterns PS00091 Thymidylate synthase active site. 180 208 - T 28-03-2018 IPR020940 Thymidylate synthase, active site GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 CO689_RS12620 56c9d609b49b9cde5e7b8c86e4e4732c 317 Gene3D G3DSA:3.30.572.10 1 317 2.5E-129 T 28-03-2018 IPR023451 Thymidylate synthase/dCMP hydroxymethylase domain KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 CO689_RS12620 56c9d609b49b9cde5e7b8c86e4e4732c 317 Hamap MF_00008 Thymidylate synthase [thyA]. 5 317 38.791 T 28-03-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 CO689_RS12620 56c9d609b49b9cde5e7b8c86e4e4732c 317 Pfam PF00303 Thymidylate synthase 7 317 9.7E-118 T 28-03-2018 IPR023451 Thymidylate synthase/dCMP hydroxymethylase domain KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 CO689_RS12620 56c9d609b49b9cde5e7b8c86e4e4732c 317 TIGRFAM TIGR03284 thym_sym: thymidylate synthase 7 317 9.1E-157 T 28-03-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 CO689_RS12620 56c9d609b49b9cde5e7b8c86e4e4732c 317 PRINTS PR00108 Thymidylate synthase family signature 195 210 3.5E-50 T 28-03-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 CO689_RS12620 56c9d609b49b9cde5e7b8c86e4e4732c 317 PRINTS PR00108 Thymidylate synthase family signature 169 188 3.5E-50 T 28-03-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 CO689_RS12620 56c9d609b49b9cde5e7b8c86e4e4732c 317 PRINTS PR00108 Thymidylate synthase family signature 46 67 3.5E-50 T 28-03-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 CO689_RS12620 56c9d609b49b9cde5e7b8c86e4e4732c 317 PRINTS PR00108 Thymidylate synthase family signature 213 239 3.5E-50 T 28-03-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 CO689_RS12620 56c9d609b49b9cde5e7b8c86e4e4732c 317 PRINTS PR00108 Thymidylate synthase family signature 251 268 3.5E-50 T 28-03-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 CO689_RS10765 281f12cf67d52f291459fa566e452cf9 415 ProSitePatterns PS00184 Phosphoribosylglycinamide synthetase signature. 284 291 - T 28-03-2018 IPR020559 Phosphoribosylglycinamide synthetase, conserved site GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CO689_RS10765 281f12cf67d52f291459fa566e452cf9 415 Pfam PF02844 Phosphoribosylglycinamide synthetase, N domain 1 101 9.5E-31 T 28-03-2018 IPR020562 Phosphoribosylglycinamide synthetase, N-terminal GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CO689_RS10765 281f12cf67d52f291459fa566e452cf9 415 Gene3D G3DSA:3.90.600.10 322 411 1.2E-25 T 28-03-2018 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CO689_RS10765 281f12cf67d52f291459fa566e452cf9 415 Pfam PF01071 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain 102 290 1.1E-67 T 28-03-2018 IPR020561 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CO689_RS10765 281f12cf67d52f291459fa566e452cf9 415 Gene3D G3DSA:3.30.470.20 185 320 1.4E-51 T 28-03-2018 CO689_RS10765 281f12cf67d52f291459fa566e452cf9 415 Gene3D G3DSA:3.30.1490.20 87 183 1.8E-23 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CO689_RS10765 281f12cf67d52f291459fa566e452cf9 415 SMART SM01210 322 411 1.3E-36 T 28-03-2018 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CO689_RS10765 281f12cf67d52f291459fa566e452cf9 415 Pfam PF02843 Phosphoribosylglycinamide synthetase, C domain 324 408 2.4E-23 T 28-03-2018 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CO689_RS10765 281f12cf67d52f291459fa566e452cf9 415 SUPERFAMILY SSF52440 1 102 2.88E-30 T 28-03-2018 IPR016185 Pre-ATP-grasp domain CO689_RS10765 281f12cf67d52f291459fa566e452cf9 415 SUPERFAMILY SSF56059 103 318 7.07E-56 T 28-03-2018 CO689_RS10765 281f12cf67d52f291459fa566e452cf9 415 SUPERFAMILY SSF51246 321 411 6.91E-24 T 28-03-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 CO689_RS10765 281f12cf67d52f291459fa566e452cf9 415 SMART SM01209 102 290 5.8E-110 T 28-03-2018 CO689_RS10765 281f12cf67d52f291459fa566e452cf9 415 Hamap MF_00138 Phosphoribosylamine--glycine ligase [purD]. 1 411 38.355 T 28-03-2018 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CO689_RS10765 281f12cf67d52f291459fa566e452cf9 415 Gene3D G3DSA:3.40.50.20 2 86 1.2E-30 T 28-03-2018 CO689_RS10765 281f12cf67d52f291459fa566e452cf9 415 TIGRFAM TIGR00877 purD: phosphoribosylamine--glycine ligase 1 411 1.5E-144 T 28-03-2018 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CO689_RS03985 6901c445ecc6289d4c5023a2bd35b2c2 151 SUPERFAMILY SSF51735 1 103 5.59E-18 T 28-03-2018 IPR016040 NAD(P)-binding domain CO689_RS03985 6901c445ecc6289d4c5023a2bd35b2c2 151 Pfam PF13241 Putative NAD(P)-binding 5 109 1.4E-20 T 28-03-2018 IPR006367 Sirohaem synthase, N-terminal GO:0006779|GO:0019354|GO:0043115|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 CO689_RS03985 6901c445ecc6289d4c5023a2bd35b2c2 151 Gene3D G3DSA:3.40.50.720 1 127 3.7E-19 T 28-03-2018 CO689_RS07930 a736229a66565b48c2a0ff6436a5bff9 147 PIRSF PIRSF021320 1 147 1.0E-46 T 28-03-2018 IPR009326 Protein of unknown function DUF984 CO689_RS07930 a736229a66565b48c2a0ff6436a5bff9 147 SMART SM01022 25 145 5.7E-36 T 28-03-2018 IPR007374 ASCH domain CO689_RS07930 a736229a66565b48c2a0ff6436a5bff9 147 Gene3D G3DSA:3.10.400.10 1 147 1.8E-51 T 28-03-2018 CO689_RS07930 a736229a66565b48c2a0ff6436a5bff9 147 SUPERFAMILY SSF88697 2 145 1.12E-45 T 28-03-2018 IPR015947 PUA-like domain CO689_RS07930 a736229a66565b48c2a0ff6436a5bff9 147 Pfam PF04266 ASCH domain 33 144 7.0E-25 T 28-03-2018 IPR007374 ASCH domain CO689_RS11560 bd83d5495e5b195c708aba2d21ebfeba 455 Hamap MF_00306 Signal recognition particle 54 kDa protein [srp54]. 6 448 35.36 T 28-03-2018 IPR022941 Signal recognition particle, SRP54 subunit GO:0003924|GO:0005525|GO:0006614|GO:0048500 Reactome: R-HSA-1799339 CO689_RS11560 bd83d5495e5b195c708aba2d21ebfeba 455 SMART SM00963 2 87 2.0E-33 T 28-03-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CO689_RS11560 bd83d5495e5b195c708aba2d21ebfeba 455 SUPERFAMILY SSF52540 43 355 2.12E-54 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CO689_RS11560 bd83d5495e5b195c708aba2d21ebfeba 455 Gene3D G3DSA:1.10.260.30 328 432 7.3E-39 T 28-03-2018 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 CO689_RS11560 bd83d5495e5b195c708aba2d21ebfeba 455 SMART SM00382 100 302 9.1E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain CO689_RS11560 bd83d5495e5b195c708aba2d21ebfeba 455 Gene3D G3DSA:3.40.50.300 94 203 6.3E-18 T 28-03-2018 CO689_RS11560 bd83d5495e5b195c708aba2d21ebfeba 455 TIGRFAM TIGR00959 ffh: signal recognition particle protein 3 429 6.2E-190 T 28-03-2018 IPR004780 Signal recognition particle protein Ffh GO:0003924|GO:0005525|GO:0006614|GO:0048500 CO689_RS11560 bd83d5495e5b195c708aba2d21ebfeba 455 Pfam PF02881 SRP54-type protein, helical bundle domain 6 83 6.6E-23 T 28-03-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CO689_RS11560 bd83d5495e5b195c708aba2d21ebfeba 455 Gene3D G3DSA:1.20.120.140 204 311 6.6E-33 T 28-03-2018 CO689_RS11560 bd83d5495e5b195c708aba2d21ebfeba 455 SMART SM00962 101 297 1.7E-115 T 28-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CO689_RS11560 bd83d5495e5b195c708aba2d21ebfeba 455 Gene3D G3DSA:1.20.120.140 1 92 1.1E-30 T 28-03-2018 CO689_RS11560 bd83d5495e5b195c708aba2d21ebfeba 455 ProSitePatterns PS00300 SRP54-type proteins GTP-binding domain signature. 270 283 - T 28-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CO689_RS11560 bd83d5495e5b195c708aba2d21ebfeba 455 Pfam PF00448 SRP54-type protein, GTPase domain 101 297 5.2E-77 T 28-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CO689_RS11560 bd83d5495e5b195c708aba2d21ebfeba 455 SUPERFAMILY SSF47446 329 430 1.13E-37 T 28-03-2018 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 CO689_RS11560 bd83d5495e5b195c708aba2d21ebfeba 455 Pfam PF02978 Signal peptide binding domain 329 427 8.9E-34 T 28-03-2018 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 CO689_RS11665 7f1abe393a8fc478902a2b948a7b158c 468 SMART SM01086 360 456 1.5E-23 T 28-03-2018 IPR019489 Clp ATPase, C-terminal CO689_RS11665 7f1abe393a8fc478902a2b948a7b158c 468 Pfam PF07724 AAA domain (Cdc48 subfamily) 220 354 2.7E-35 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CO689_RS11665 7f1abe393a8fc478902a2b948a7b158c 468 Gene3D G3DSA:1.10.8.60 360 456 6.8E-29 T 28-03-2018 CO689_RS11665 7f1abe393a8fc478902a2b948a7b158c 468 Gene3D G3DSA:3.40.50.300 5 357 5.9E-47 T 28-03-2018 CO689_RS11665 7f1abe393a8fc478902a2b948a7b158c 468 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 360 431 1.2E-6 T 28-03-2018 IPR019489 Clp ATPase, C-terminal CO689_RS11665 7f1abe393a8fc478902a2b948a7b158c 468 TIGRFAM TIGR00390 hslU: ATP-dependent protease HslVU, ATPase subunit 8 468 2.8E-192 T 28-03-2018 IPR004491 Heat shock protein HslU GO:0005524|GO:0005737|GO:0009376|GO:0016887|GO:0070011 CO689_RS11665 7f1abe393a8fc478902a2b948a7b158c 468 SMART SM00382 53 357 2.5E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain CO689_RS11665 7f1abe393a8fc478902a2b948a7b158c 468 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 57 107 4.6E-6 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CO689_RS11665 7f1abe393a8fc478902a2b948a7b158c 468 SUPERFAMILY SSF52540 203 463 6.05E-77 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CO689_RS11665 7f1abe393a8fc478902a2b948a7b158c 468 SUPERFAMILY SSF52540 8 143 6.05E-77 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CO689_RS11665 7f1abe393a8fc478902a2b948a7b158c 468 Hamap MF_00249 ATP-dependent protease ATPase subunit HslU [hslU]. 5 468 42.307 T 28-03-2018 IPR004491 Heat shock protein HslU GO:0005524|GO:0005737|GO:0009376|GO:0016887|GO:0070011 CO689_RS09830 627ac9790b4440c9efe1765252057e97 295 SUPERFAMILY SSF54001 23 150 1.54E-20 T 28-03-2018 CO689_RS09830 627ac9790b4440c9efe1765252057e97 295 Gene3D G3DSA:3.90.1720.10 4 136 2.4E-6 T 28-03-2018 CO689_RS09830 627ac9790b4440c9efe1765252057e97 295 Pfam PF08460 Bacterial SH3 domain 209 274 7.6E-24 T 28-03-2018 IPR003646 SH3-like domain, bacterial-type CO689_RS09830 627ac9790b4440c9efe1765252057e97 295 Pfam PF05257 CHAP domain 27 117 7.2E-14 T 28-03-2018 IPR007921 CHAP domain CO689_RS09830 627ac9790b4440c9efe1765252057e97 295 SMART SM00287 212 280 4.5E-10 T 28-03-2018 IPR003646 SH3-like domain, bacterial-type CO689_RS09830 627ac9790b4440c9efe1765252057e97 295 Gene3D G3DSA:2.30.30.410 146 295 1.2E-5 T 28-03-2018 CO689_RS07540 59ff5032db31bbcf18a21daa2f8bfa15 198 SMART SM00278 12 31 0.0049 T 28-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 CO689_RS07540 59ff5032db31bbcf18a21daa2f8bfa15 198 Hamap MF_00017 Recombination protein RecR [recR]. 1 198 111.316 T 28-03-2018 IPR000093 DNA recombination protein RecR GO:0003677|GO:0006281|GO:0006310 CO689_RS07540 59ff5032db31bbcf18a21daa2f8bfa15 198 TIGRFAM TIGR00615 recR: recombination protein RecR 2 196 5.0E-89 T 28-03-2018 IPR000093 DNA recombination protein RecR GO:0003677|GO:0006281|GO:0006310 CO689_RS07540 59ff5032db31bbcf18a21daa2f8bfa15 198 SUPERFAMILY SSF111304 1 198 6.93E-79 T 28-03-2018 IPR023627 Recombination protein RecR CO689_RS07540 59ff5032db31bbcf18a21daa2f8bfa15 198 ProSitePatterns PS01300 RecR protein signature. 57 78 - T 28-03-2018 IPR015967 Recombination protein RecR, conserved site GO:0006281|GO:0006310 CO689_RS07540 59ff5032db31bbcf18a21daa2f8bfa15 198 Gene3D G3DSA:3.40.1360.10 77 170 1.3E-39 T 28-03-2018 CO689_RS07540 59ff5032db31bbcf18a21daa2f8bfa15 198 SMART SM00493 80 165 1.6E-15 T 28-03-2018 IPR006171 TOPRIM domain CO689_RS07540 59ff5032db31bbcf18a21daa2f8bfa15 198 Pfam PF02132 RecR protein 40 78 1.6E-16 T 28-03-2018 IPR023628 Recombination protein RecR, C4-type zinc finger CO689_RS07540 59ff5032db31bbcf18a21daa2f8bfa15 198 Pfam PF13662 Toprim domain 80 171 1.4E-26 T 28-03-2018 IPR006171 TOPRIM domain CO689_RS07540 59ff5032db31bbcf18a21daa2f8bfa15 198 Gene3D G3DSA:1.10.150.20 8 38 0.0014 T 28-03-2018 CO689_RS04210 94ce8a8e7952a3adb98b9614cfec71f0 722 Pfam PF13090 Polyphosphate kinase C-terminal domain 342 681 5.6E-151 T 28-03-2018 IPR025200 Polyphosphate kinase C-terminal domain KEGG: 00190+2.7.4.1 CO689_RS04210 94ce8a8e7952a3adb98b9614cfec71f0 722 SUPERFAMILY SSF56024 507 686 3.59E-72 T 28-03-2018 CO689_RS04210 94ce8a8e7952a3adb98b9614cfec71f0 722 Hamap MF_00347 Polyphosphate kinase [ppk]. 14 686 28.743 T 28-03-2018 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 CO689_RS04210 94ce8a8e7952a3adb98b9614cfec71f0 722 PIRSF PIRSF015589 1 699 6.4E-261 T 28-03-2018 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 CO689_RS04210 94ce8a8e7952a3adb98b9614cfec71f0 722 Gene3D G3DSA:3.30.1840.10 121 310 1.2E-59 T 28-03-2018 IPR024953 Polyphosphate kinase middle domain KEGG: 00190+2.7.4.1 CO689_RS04210 94ce8a8e7952a3adb98b9614cfec71f0 722 Gene3D G3DSA:3.30.870.10 325 505 2.1E-20 T 28-03-2018 CO689_RS04210 94ce8a8e7952a3adb98b9614cfec71f0 722 SUPERFAMILY SSF143724 121 315 4.12E-53 T 28-03-2018 CO689_RS04210 94ce8a8e7952a3adb98b9614cfec71f0 722 Pfam PF13089 Polyphosphate kinase N-terminal domain 16 119 4.6E-37 T 28-03-2018 IPR025198 Polyphosphate kinase N-terminal domain KEGG: 00190+2.7.4.1 CO689_RS04210 94ce8a8e7952a3adb98b9614cfec71f0 722 SUPERFAMILY SSF140356 13 118 1.57E-36 T 28-03-2018 IPR025198 Polyphosphate kinase N-terminal domain KEGG: 00190+2.7.4.1 CO689_RS04210 94ce8a8e7952a3adb98b9614cfec71f0 722 Gene3D G3DSA:1.20.58.310 18 120 8.4E-36 T 28-03-2018 CO689_RS04210 94ce8a8e7952a3adb98b9614cfec71f0 722 Gene3D G3DSA:3.30.870.10 506 691 4.9E-33 T 28-03-2018 CO689_RS04210 94ce8a8e7952a3adb98b9614cfec71f0 722 Pfam PF02503 Polyphosphate kinase middle domain 133 328 4.0E-59 T 28-03-2018 IPR024953 Polyphosphate kinase middle domain KEGG: 00190+2.7.4.1 CO689_RS04210 94ce8a8e7952a3adb98b9614cfec71f0 722 TIGRFAM TIGR03705 poly_P_kin: polyphosphate kinase 1 16 682 2.3E-267 T 28-03-2018 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 CO689_RS04210 94ce8a8e7952a3adb98b9614cfec71f0 722 SUPERFAMILY SSF56024 328 502 6.28E-53 T 28-03-2018 CO689_RS01990 74af8ac3ecb6b4426b7581050fcd3094 102 Pfam PF05521 Phage head-tail joining protein 6 97 2.7E-18 T 28-03-2018 IPR008767 Bacteriophage SPP1, head-tail adaptor CO689_RS01990 74af8ac3ecb6b4426b7581050fcd3094 102 TIGRFAM TIGR01563 gp16_SPP1: putative phage head-tail adaptor 5 96 2.2E-10 T 28-03-2018 IPR008767 Bacteriophage SPP1, head-tail adaptor CO689_RS10965 85c48078839408f6877698a52f110e5b 1149 Pfam PF00364 Biotin-requiring enzyme 1080 1145 1.1E-17 T 28-03-2018 IPR000089 Biotin/lipoyl attachment CO689_RS10965 85c48078839408f6877698a52f110e5b 1149 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 156 170 - T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CO689_RS10965 85c48078839408f6877698a52f110e5b 1149 SUPERFAMILY SSF51246 340 457 2.04E-37 T 28-03-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 CO689_RS10965 85c48078839408f6877698a52f110e5b 1149 PIRSF PIRSF001594 1 1147 0.0 T 28-03-2018 IPR005930 Pyruvate carboxylase GO:0004736|GO:0005524|GO:0006090|GO:0006094|GO:0009374 KEGG: 00020+6.4.1.1|KEGG: 00620+6.4.1.1|KEGG: 00720+6.4.1.1|MetaCyc: PWY-5750|MetaCyc: PWY-6142|MetaCyc: PWY-6146|Reactome: R-HSA-196780|Reactome: R-HSA-3371599|Reactome: R-HSA-70263 CO689_RS10965 85c48078839408f6877698a52f110e5b 1149 Gene3D G3DSA:3.30.470.20 213 453 4.2E-92 T 28-03-2018 CO689_RS10965 85c48078839408f6877698a52f110e5b 1149 Gene3D G3DSA:2.40.50.100 1075 1147 2.2E-19 T 28-03-2018 CO689_RS10965 85c48078839408f6877698a52f110e5b 1149 Gene3D G3DSA:3.40.50.20 3 126 3.8E-49 T 28-03-2018 CO689_RS10965 85c48078839408f6877698a52f110e5b 1149 SUPERFAMILY SSF51230 1066 1146 1.31E-21 T 28-03-2018 IPR011053 Single hybrid motif CO689_RS10965 85c48078839408f6877698a52f110e5b 1149 Pfam PF02436 Conserved carboxylase domain 829 1028 1.2E-74 T 28-03-2018 IPR003379 Carboxylase, conserved domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599|Reactome: R-HSA-70263 CO689_RS10965 85c48078839408f6877698a52f110e5b 1149 SUPERFAMILY SSF51569 525 837 1.59E-82 T 28-03-2018 CO689_RS10965 85c48078839408f6877698a52f110e5b 1149 Gene3D G3DSA:3.10.600.10 993 1062 5.2E-21 T 28-03-2018 CO689_RS10965 85c48078839408f6877698a52f110e5b 1149 Gene3D G3DSA:3.30.1490.20 127 212 6.3E-22 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CO689_RS10965 85c48078839408f6877698a52f110e5b 1149 Pfam PF02785 Biotin carboxylase C-terminal domain 344 452 8.6E-33 T 28-03-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CO689_RS10965 85c48078839408f6877698a52f110e5b 1149 Gene3D G3DSA:1.10.10.60 945 992 1.3E-18 T 28-03-2018 CO689_RS10965 85c48078839408f6877698a52f110e5b 1149 TIGRFAM TIGR01235 pyruv_carbox: pyruvate carboxylase 6 1146 0.0 T 28-03-2018 IPR005930 Pyruvate carboxylase GO:0004736|GO:0005524|GO:0006090|GO:0006094|GO:0009374 KEGG: 00020+6.4.1.1|KEGG: 00620+6.4.1.1|KEGG: 00720+6.4.1.1|MetaCyc: PWY-5750|MetaCyc: PWY-6142|MetaCyc: PWY-6146|Reactome: R-HSA-196780|Reactome: R-HSA-3371599|Reactome: R-HSA-70263 CO689_RS10965 85c48078839408f6877698a52f110e5b 1149 Gene3D G3DSA:3.10.600.10 463 534 1.7E-19 T 28-03-2018 CO689_RS10965 85c48078839408f6877698a52f110e5b 1149 Gene3D G3DSA:3.20.20.70 535 821 1.7E-68 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CO689_RS10965 85c48078839408f6877698a52f110e5b 1149 SUPERFAMILY SSF52440 3 115 1.15E-43 T 28-03-2018 IPR016185 Pre-ATP-grasp domain CO689_RS10965 85c48078839408f6877698a52f110e5b 1149 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 288 295 - T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CO689_RS10965 85c48078839408f6877698a52f110e5b 1149 SUPERFAMILY SSF56059 86 352 1.43E-66 T 28-03-2018 CO689_RS10965 85c48078839408f6877698a52f110e5b 1149 SUPERFAMILY SSF89000 834 1011 1.33E-56 T 28-03-2018 CO689_RS10965 85c48078839408f6877698a52f110e5b 1149 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 118 323 6.8E-77 T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CO689_RS10965 85c48078839408f6877698a52f110e5b 1149 SMART SM00878 344 451 5.4E-51 T 28-03-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CO689_RS10965 85c48078839408f6877698a52f110e5b 1149 Pfam PF00682 HMGL-like 533 806 1.2E-28 T 28-03-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 CO689_RS10965 85c48078839408f6877698a52f110e5b 1149 Pfam PF00289 Biotin carboxylase, N-terminal domain 4 112 5.0E-42 T 28-03-2018 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CO689_RS03935 d3f67dea209385e412223b78fed1d30d 217 Pfam PF00196 Bacterial regulatory proteins, luxR family 154 209 2.6E-22 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CO689_RS03935 d3f67dea209385e412223b78fed1d30d 217 ProSitePatterns PS00622 LuxR-type HTH domain signature. 169 196 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CO689_RS03935 d3f67dea209385e412223b78fed1d30d 217 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 155 169 1.9E-14 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CO689_RS03935 d3f67dea209385e412223b78fed1d30d 217 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 185 197 1.9E-14 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CO689_RS03935 d3f67dea209385e412223b78fed1d30d 217 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 169 185 1.9E-14 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CO689_RS03935 d3f67dea209385e412223b78fed1d30d 217 SUPERFAMILY SSF52172 2 133 4.41E-29 T 28-03-2018 IPR011006 CheY-like superfamily CO689_RS03935 d3f67dea209385e412223b78fed1d30d 217 SMART SM00421 152 209 7.0E-25 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CO689_RS03935 d3f67dea209385e412223b78fed1d30d 217 Pfam PF00072 Response regulator receiver domain 3 115 1.8E-24 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CO689_RS03935 d3f67dea209385e412223b78fed1d30d 217 Gene3D G3DSA:1.10.10.10 127 217 1.5E-25 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS03935 d3f67dea209385e412223b78fed1d30d 217 SMART SM00448 1 115 5.5E-22 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CO689_RS03935 d3f67dea209385e412223b78fed1d30d 217 Gene3D G3DSA:3.40.50.2300 1 126 6.1E-29 T 28-03-2018 CO689_RS03935 d3f67dea209385e412223b78fed1d30d 217 SUPERFAMILY SSF46894 148 215 3.2E-21 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CO689_RS00990 d81a33ac16a013d0c0e437a2d188c7d3 437 Hamap MF_00046 UDP-N-acetylmuramate--L-alanine ligase [murC]. 1 433 34.611 T 28-03-2018 IPR005758 UDP-N-acetylmuramate--L-alanine ligase GO:0008763|GO:0009252 KEGG: 00471+6.3.2.8|KEGG: 00550+6.3.2.8|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CO689_RS00990 d81a33ac16a013d0c0e437a2d188c7d3 437 Pfam PF01225 Mur ligase family, catalytic domain 3 101 1.3E-22 T 28-03-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 CO689_RS00990 d81a33ac16a013d0c0e437a2d188c7d3 437 Gene3D G3DSA:3.90.190.20 296 433 4.2E-25 T 28-03-2018 CO689_RS00990 d81a33ac16a013d0c0e437a2d188c7d3 437 SUPERFAMILY SSF51984 1 88 2.35E-21 T 28-03-2018 CO689_RS00990 d81a33ac16a013d0c0e437a2d188c7d3 437 Pfam PF08245 Mur ligase middle domain 106 275 4.3E-23 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CO689_RS00990 d81a33ac16a013d0c0e437a2d188c7d3 437 Gene3D G3DSA:3.40.1190.10 91 295 1.1E-38 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CO689_RS00990 d81a33ac16a013d0c0e437a2d188c7d3 437 Pfam PF02875 Mur ligase family, glutamate ligase domain 295 373 2.8E-20 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CO689_RS00990 d81a33ac16a013d0c0e437a2d188c7d3 437 SUPERFAMILY SSF53244 294 428 4.94E-35 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CO689_RS00990 d81a33ac16a013d0c0e437a2d188c7d3 437 Gene3D G3DSA:3.40.50.720 4 89 9.9E-6 T 28-03-2018 CO689_RS00990 d81a33ac16a013d0c0e437a2d188c7d3 437 TIGRFAM TIGR01082 murC: UDP-N-acetylmuramate--L-alanine ligase 3 425 8.5E-126 T 28-03-2018 IPR005758 UDP-N-acetylmuramate--L-alanine ligase GO:0008763|GO:0009252 KEGG: 00471+6.3.2.8|KEGG: 00550+6.3.2.8|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CO689_RS00990 d81a33ac16a013d0c0e437a2d188c7d3 437 SUPERFAMILY SSF53623 87 293 1.23E-55 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CO689_RS04300 f615b941c1ffc1d5ffd143b5861a53bc 982 Pfam PF02837 Glycosyl hydrolases family 2, sugar binding domain 35 197 7.0E-41 T 28-03-2018 IPR006104 Glycosyl hydrolases family 2, sugar binding domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 CO689_RS04300 f615b941c1ffc1d5ffd143b5861a53bc 982 Pfam PF02836 Glycosyl hydrolases family 2, TIM barrel domain 293 588 7.5E-95 T 28-03-2018 IPR006103 Glycoside hydrolase family 2, catalytic domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-6798695 CO689_RS04300 f615b941c1ffc1d5ffd143b5861a53bc 982 Gene3D G3DSA:2.60.120.260 4 197 4.0E-48 T 28-03-2018 IPR008979 Galactose-binding domain-like CO689_RS04300 f615b941c1ffc1d5ffd143b5861a53bc 982 SUPERFAMILY SSF51445 293 585 2.32E-86 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CO689_RS04300 f615b941c1ffc1d5ffd143b5861a53bc 982 SUPERFAMILY SSF74650 698 977 5.34E-71 T 28-03-2018 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 CO689_RS04300 f615b941c1ffc1d5ffd143b5861a53bc 982 ProSitePatterns PS00719 Glycosyl hydrolases family 2 signature 1. 343 368 - T 28-03-2018 IPR023230 Glycoside hydrolase, family 2, conserved site KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-6798695 CO689_RS04300 f615b941c1ffc1d5ffd143b5861a53bc 982 Gene3D G3DSA:2.60.40.10 198 291 1.4E-16 T 28-03-2018 IPR013783 Immunoglobulin-like fold CO689_RS04300 f615b941c1ffc1d5ffd143b5861a53bc 982 SUPERFAMILY SSF49303 200 292 1.96E-17 T 28-03-2018 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 CO689_RS04300 f615b941c1ffc1d5ffd143b5861a53bc 982 Gene3D G3DSA:3.20.20.80 292 586 2.6E-71 T 28-03-2018 CO689_RS04300 f615b941c1ffc1d5ffd143b5861a53bc 982 Pfam PF02929 Beta galactosidase small chain 711 976 1.4E-60 T 28-03-2018 IPR004199 Beta galactosidase small chain/ domain 5 GO:0004565|GO:0005975|GO:0009341 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 CO689_RS04300 f615b941c1ffc1d5ffd143b5861a53bc 982 Pfam PF00703 Glycosyl hydrolases family 2 200 291 6.9E-8 T 28-03-2018 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 CO689_RS04300 f615b941c1ffc1d5ffd143b5861a53bc 982 Gene3D G3DSA:2.70.98.10 692 979 1.8E-75 T 28-03-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 CO689_RS04300 f615b941c1ffc1d5ffd143b5861a53bc 982 SMART SM01038 709 977 2.0E-65 T 28-03-2018 IPR004199 Beta galactosidase small chain/ domain 5 GO:0004565|GO:0005975|GO:0009341 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 CO689_RS04300 f615b941c1ffc1d5ffd143b5861a53bc 982 PRINTS PR00132 Glycosyl hydrolase family 2 signature 414 429 4.9E-30 T 28-03-2018 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-6798695 CO689_RS04300 f615b941c1ffc1d5ffd143b5861a53bc 982 PRINTS PR00132 Glycosyl hydrolase family 2 signature 302 316 4.9E-30 T 28-03-2018 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-6798695 CO689_RS04300 f615b941c1ffc1d5ffd143b5861a53bc 982 PRINTS PR00132 Glycosyl hydrolase family 2 signature 333 351 4.9E-30 T 28-03-2018 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-6798695 CO689_RS04300 f615b941c1ffc1d5ffd143b5861a53bc 982 PRINTS PR00132 Glycosyl hydrolase family 2 signature 125 140 4.9E-30 T 28-03-2018 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-6798695 CO689_RS04300 f615b941c1ffc1d5ffd143b5861a53bc 982 PRINTS PR00132 Glycosyl hydrolase family 2 signature 493 508 4.9E-30 T 28-03-2018 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-6798695 CO689_RS04300 f615b941c1ffc1d5ffd143b5861a53bc 982 SUPERFAMILY SSF49785 5 197 5.53E-51 T 28-03-2018 IPR008979 Galactose-binding domain-like CO689_RS11515 a1e155ff31830a6f26af2afba1e3beb4 185 Pfam PF08220 DeoR-like helix-turn-helix domain 8 48 2.0E-4 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CO689_RS11515 a1e155ff31830a6f26af2afba1e3beb4 185 Gene3D G3DSA:1.10.10.10 1 60 8.7E-6 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS11515 a1e155ff31830a6f26af2afba1e3beb4 185 Pfam PF03061 Thioesterase superfamily 102 164 3.1E-6 T 28-03-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 CO689_RS11515 a1e155ff31830a6f26af2afba1e3beb4 185 Gene3D G3DSA:3.10.129.10 61 185 4.5E-16 T 28-03-2018 CO689_RS11515 a1e155ff31830a6f26af2afba1e3beb4 185 SUPERFAMILY SSF54637 73 180 1.68E-17 T 28-03-2018 IPR029069 HotDog domain CO689_RS11515 a1e155ff31830a6f26af2afba1e3beb4 185 PIRSF PIRSF037733 1 185 6.7E-75 T 28-03-2018 IPR017275 Transcription factor FapR GO:0003700|GO:0045717|GO:0045892 CO689_RS13870 1abe290919d4cd65cc83585490f20541 431 Pfam PF07085 DRTGG domain 75 177 1.9E-29 T 28-03-2018 IPR010766 DRTGG KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 CO689_RS13870 1abe290919d4cd65cc83585490f20541 431 SUPERFAMILY SSF54637 333 429 3.88E-6 T 28-03-2018 IPR029069 HotDog domain CO689_RS13870 1abe290919d4cd65cc83585490f20541 431 Gene3D G3DSA:3.40.1390.20 69 189 1.8E-26 T 28-03-2018 IPR028979 HPr(Ser) kinase/phosphorylase, N-terminal domain-like CO689_RS13870 1abe290919d4cd65cc83585490f20541 431 Gene3D G3DSA:3.10.129.10 300 431 2.9E-11 T 28-03-2018 CO689_RS13870 1abe290919d4cd65cc83585490f20541 431 Gene3D G3DSA:3.10.580.10 190 299 1.2E-24 T 28-03-2018 CO689_RS13870 1abe290919d4cd65cc83585490f20541 431 Gene3D G3DSA:1.10.260.40 32 68 9.8E-4 T 28-03-2018 CO689_RS13870 1abe290919d4cd65cc83585490f20541 431 SMART SM00116 258 306 0.039 T 28-03-2018 IPR000644 CBS domain CO689_RS13870 1abe290919d4cd65cc83585490f20541 431 SMART SM00116 199 247 1.2E-5 T 28-03-2018 IPR000644 CBS domain CO689_RS13870 1abe290919d4cd65cc83585490f20541 431 SUPERFAMILY SSF54631 180 305 4.93E-27 T 28-03-2018 CO689_RS13870 1abe290919d4cd65cc83585490f20541 431 Gene3D G3DSA:1.10.10.60 2 31 2.2E-4 T 28-03-2018 CO689_RS13870 1abe290919d4cd65cc83585490f20541 431 Pfam PF00571 CBS domain 254 305 3.0E-6 T 28-03-2018 IPR000644 CBS domain CO689_RS13870 1abe290919d4cd65cc83585490f20541 431 Pfam PF00571 CBS domain 191 245 4.8E-9 T 28-03-2018 IPR000644 CBS domain CO689_RS13870 1abe290919d4cd65cc83585490f20541 431 Pfam PF00392 Bacterial regulatory proteins, gntR family 6 58 5.9E-6 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CO689_RS13870 1abe290919d4cd65cc83585490f20541 431 SUPERFAMILY SSF75138 71 183 2.22E-29 T 28-03-2018 IPR028979 HPr(Ser) kinase/phosphorylase, N-terminal domain-like CO689_RS11010 129b8782af49be9cf33c4171ada1c9dc 183 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 115 121 - T 28-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 CO689_RS11010 129b8782af49be9cf33c4171ada1c9dc 183 Pfam PF03602 Conserved hypothetical protein 95 1 174 9.2E-54 T 28-03-2018 CO689_RS11010 129b8782af49be9cf33c4171ada1c9dc 183 SUPERFAMILY SSF53335 1 170 2.2E-44 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CO689_RS11010 129b8782af49be9cf33c4171ada1c9dc 183 Gene3D G3DSA:3.40.50.150 1 182 1.1E-30 T 28-03-2018 CO689_RS11010 129b8782af49be9cf33c4171ada1c9dc 183 PIRSF PIRSF004553 1 179 1.2E-47 T 28-03-2018 IPR004398 RNA methyltransferase, RsmD GO:0008168|GO:0031167 CO689_RS11010 129b8782af49be9cf33c4171ada1c9dc 183 TIGRFAM TIGR00095 TIGR00095: 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD 2 177 1.2E-49 T 28-03-2018 IPR004398 RNA methyltransferase, RsmD GO:0008168|GO:0031167 CO689_RS13640 7cf20ec6eee47571bf8f93458d191a35 630 Pfam PF00589 Phage integrase family 330 505 2.9E-44 T 28-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 CO689_RS13640 7cf20ec6eee47571bf8f93458d191a35 630 Gene3D G3DSA:1.10.443.10 329 510 1.5E-34 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 CO689_RS13640 7cf20ec6eee47571bf8f93458d191a35 630 Gene3D G3DSA:1.10.150.130 205 307 9.2E-8 T 28-03-2018 IPR023109 Integrase/recombinase, N-terminal CO689_RS13640 7cf20ec6eee47571bf8f93458d191a35 630 SUPERFAMILY SSF56349 218 511 1.38E-43 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CO689_RS12720 3e069bb83c3aec3efeabc4e20bf94ebb 896 Gene3D G3DSA:3.30.420.10 1 153 2.0E-36 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CO689_RS12720 3e069bb83c3aec3efeabc4e20bf94ebb 896 SMART SM00491 733 862 6.5E-13 T 28-03-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 CO689_RS12720 3e069bb83c3aec3efeabc4e20bf94ebb 896 SUPERFAMILY SSF52540 401 470 4.65E-21 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CO689_RS12720 3e069bb83c3aec3efeabc4e20bf94ebb 896 SUPERFAMILY SSF52540 690 857 4.65E-21 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CO689_RS12720 3e069bb83c3aec3efeabc4e20bf94ebb 896 SUPERFAMILY SSF52540 643 657 4.65E-21 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CO689_RS12720 3e069bb83c3aec3efeabc4e20bf94ebb 896 SUPERFAMILY SSF52540 262 319 4.65E-21 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CO689_RS12720 3e069bb83c3aec3efeabc4e20bf94ebb 896 Gene3D G3DSA:3.40.50.300 694 892 1.1E-10 T 28-03-2018 CO689_RS12720 3e069bb83c3aec3efeabc4e20bf94ebb 896 Pfam PF13307 Helicase C-terminal domain 716 874 8.6E-31 T 28-03-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 CO689_RS12720 3e069bb83c3aec3efeabc4e20bf94ebb 896 SMART SM00479 5 171 4.5E-38 T 28-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III CO689_RS12720 3e069bb83c3aec3efeabc4e20bf94ebb 896 Gene3D G3DSA:3.40.50.300 248 686 6.9E-18 T 28-03-2018 CO689_RS12720 3e069bb83c3aec3efeabc4e20bf94ebb 896 SUPERFAMILY SSF53098 3 172 5.36E-48 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CO689_RS12720 3e069bb83c3aec3efeabc4e20bf94ebb 896 Pfam PF00929 Exonuclease 8 161 1.2E-31 T 28-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III CO689_RS12720 3e069bb83c3aec3efeabc4e20bf94ebb 896 Pfam PF04851 Type III restriction enzyme, res subunit 250 475 1.0E-5 T 28-03-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 CO689_RS12720 3e069bb83c3aec3efeabc4e20bf94ebb 896 TIGRFAM TIGR01407 dinG_rel: putative DnaQ family exonuclease/DinG family helicase 5 881 0.0 T 28-03-2018 IPR006310 DnaQ exonuclease/DinG helicase, predicted CO689_RS12720 3e069bb83c3aec3efeabc4e20bf94ebb 896 Gene3D G3DSA:1.20.5.140 154 170 0.0021 T 28-03-2018 CO689_RS12720 3e069bb83c3aec3efeabc4e20bf94ebb 896 TIGRFAM TIGR00573 dnaq: exonuclease, DNA polymerase III, epsilon subunit family 3 168 2.0E-30 T 28-03-2018 IPR006054 DNA polymerase III epsilon subunit, exonuclease domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CO689_RS08925 d686558f3c65177132c0c5b1740555d6 334 SUPERFAMILY SSF50891 201 303 4.55E-5 T 28-03-2018 IPR029000 Cyclophilin-like domain CO689_RS08925 d686558f3c65177132c0c5b1740555d6 334 Pfam PF02626 Carboxyltransferase domain, subdomain A and B 26 299 1.6E-67 T 28-03-2018 IPR003778 Carboxyltransferase domain, subdomain A and B CO689_RS08925 d686558f3c65177132c0c5b1740555d6 334 SMART SM00797 24 316 4.0E-95 T 28-03-2018 IPR003778 Carboxyltransferase domain, subdomain A and B CO689_RS08530 1c337c68b08e7424f2a75a2000262a4a 332 SUPERFAMILY SSF81345 7 327 8.89E-78 T 28-03-2018 IPR029022 ABC transporter, BtuC-like CO689_RS08530 1c337c68b08e7424f2a75a2000262a4a 332 Pfam PF01032 FecCD transport family 23 327 1.6E-86 T 28-03-2018 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 CO689_RS08530 1c337c68b08e7424f2a75a2000262a4a 332 Gene3D G3DSA:1.10.3470.10 5 332 1.5E-66 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CO689_RS08600 d37d904d68be4cac03a340669e60648d 724 SMART SM00342 167 250 4.1E-21 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CO689_RS08600 d37d904d68be4cac03a340669e60648d 724 Gene3D G3DSA:2.60.40.1500 576 723 4.7E-10 T 28-03-2018 CO689_RS08600 d37d904d68be4cac03a340669e60648d 724 SUPERFAMILY SSF46689 152 200 1.55E-5 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CO689_RS08600 d37d904d68be4cac03a340669e60648d 724 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 204 246 - T 28-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 CO689_RS08600 d37d904d68be4cac03a340669e60648d 724 SUPERFAMILY SSF46689 203 252 5.38E-10 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CO689_RS08600 d37d904d68be4cac03a340669e60648d 724 Pfam PF12833 Helix-turn-helix domain 174 251 7.4E-15 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CO689_RS08600 d37d904d68be4cac03a340669e60648d 724 Gene3D G3DSA:3.90.1240.10 44 389 1.1E-22 T 28-03-2018 CO689_RS09920 da5d3dc28ce05dad4eed4b5ecab2d7d8 384 SUPERFAMILY SSF52266 290 383 4.76E-7 T 28-03-2018 IPR013830 SGNH hydrolase-type esterase domain CO689_RS09920 da5d3dc28ce05dad4eed4b5ecab2d7d8 384 PIRSF PIRSF021438 1 384 2.3E-91 T 28-03-2018 IPR023896 D-alanyl-lipoteichoic acid biosynthesis DltD, Firmicutes CO689_RS09920 da5d3dc28ce05dad4eed4b5ecab2d7d8 384 TIGRFAM TIGR04092 LTA_DltD: D-alanyl-lipoteichoic acid biosynthesis protein DltD 8 381 3.3E-106 T 28-03-2018 IPR023896 D-alanyl-lipoteichoic acid biosynthesis DltD, Firmicutes CO689_RS09920 da5d3dc28ce05dad4eed4b5ecab2d7d8 384 Pfam PF04914 DltD protein 43 382 9.3E-99 T 28-03-2018 IPR006998 DltD CO689_RS09920 da5d3dc28ce05dad4eed4b5ecab2d7d8 384 Gene3D G3DSA:3.40.50.1110 95 384 0.0012 T 28-03-2018 CO689_RS11670 7cf2c3b3a99dd49d955160f334c14ffa 257 SUPERFAMILY SSF46785 167 256 9.67E-41 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS11670 7cf2c3b3a99dd49d955160f334c14ffa 257 Pfam PF08222 CodY helix-turn-helix domain 197 257 2.2E-34 T 28-03-2018 IPR013198 GTP-sensing helix-turn-helix, CodY, C-terminal CO689_RS11670 7cf2c3b3a99dd49d955160f334c14ffa 257 Gene3D G3DSA:1.10.10.10 160 257 1.5E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS11670 7cf2c3b3a99dd49d955160f334c14ffa 257 PIRSF PIRSF011572 1 257 4.2E-115 T 28-03-2018 IPR014154 GTP-sensing transcriptional pleiotropic repressor CodY GO:0003677|GO:0003700|GO:0005525|GO:0045892 CO689_RS11670 7cf2c3b3a99dd49d955160f334c14ffa 257 Pfam PF06018 CodY GAF-like domain 2 178 6.5E-69 T 28-03-2018 IPR010312 GTP-sensing transcriptional pleiotropic repressor CodY, N-terminal GO:0003677|GO:0005525 CO689_RS11670 7cf2c3b3a99dd49d955160f334c14ffa 257 Gene3D G3DSA:3.30.450.40 1 159 6.0E-24 T 28-03-2018 IPR029016 GAF domain-like CO689_RS11670 7cf2c3b3a99dd49d955160f334c14ffa 257 Hamap MF_00621 GTP-sensing transcriptional pleiotropic repressor CodY [codY]. 1 257 132.51 T 28-03-2018 IPR014154 GTP-sensing transcriptional pleiotropic repressor CodY GO:0003677|GO:0003700|GO:0005525|GO:0045892 CO689_RS11670 7cf2c3b3a99dd49d955160f334c14ffa 257 TIGRFAM TIGR02787 codY_Gpos: GTP-sensing transcriptional pleiotropic repressor CodY 3 253 3.6E-107 T 28-03-2018 IPR014154 GTP-sensing transcriptional pleiotropic repressor CodY GO:0003677|GO:0003700|GO:0005525|GO:0045892 CO689_RS02475 895735dbdcf1b6f80fc09b21339e68d9 241 SUPERFAMILY SSF81336 75 234 2.75E-38 T 28-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CO689_RS02475 895735dbdcf1b6f80fc09b21339e68d9 241 Pfam PF00119 ATP synthase A chain 24 234 3.0E-55 T 28-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CO689_RS02475 895735dbdcf1b6f80fc09b21339e68d9 241 ProSitePatterns PS00449 ATP synthase a subunit signature. 169 178 - T 28-03-2018 IPR023011 ATP synthase, F0 complex, subunit A, active site Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CO689_RS02475 895735dbdcf1b6f80fc09b21339e68d9 241 TIGRFAM TIGR01131 ATP_synt_6_or_A: ATP synthase F0, A subunit 19 236 6.5E-44 T 28-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CO689_RS02475 895735dbdcf1b6f80fc09b21339e68d9 241 Gene3D G3DSA:1.20.120.220 73 241 6.9E-41 T 28-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CO689_RS02475 895735dbdcf1b6f80fc09b21339e68d9 241 Hamap MF_01393 ATP synthase subunit a [atpB]. 1 240 13.535 T 28-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CO689_RS02475 895735dbdcf1b6f80fc09b21339e68d9 241 PRINTS PR00123 ATP synthase A subunit signature 220 235 3.2E-19 T 28-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CO689_RS02475 895735dbdcf1b6f80fc09b21339e68d9 241 PRINTS PR00123 ATP synthase A subunit signature 166 188 3.2E-19 T 28-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CO689_RS02475 895735dbdcf1b6f80fc09b21339e68d9 241 PRINTS PR00123 ATP synthase A subunit signature 150 165 3.2E-19 T 28-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CO689_RS02475 895735dbdcf1b6f80fc09b21339e68d9 241 PRINTS PR00123 ATP synthase A subunit signature 82 98 3.2E-19 T 28-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CO689_RS00910 f3f4c2b42b22559fbaa63a3b74b8c7d2 385 Gene3D G3DSA:3.90.1150.10 269 385 7.1E-31 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CO689_RS00910 f3f4c2b42b22559fbaa63a3b74b8c7d2 385 SUPERFAMILY SSF53383 4 364 8.34E-94 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CO689_RS00910 f3f4c2b42b22559fbaa63a3b74b8c7d2 385 Gene3D G3DSA:3.40.640.10 13 268 3.5E-33 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CO689_RS00910 f3f4c2b42b22559fbaa63a3b74b8c7d2 385 Pfam PF00266 Aminotransferase class-V 7 332 1.1E-39 T 28-03-2018 IPR000192 Aminotransferase class V domain CO689_RS00910 f3f4c2b42b22559fbaa63a3b74b8c7d2 385 PIRSF PIRSF000524 1 384 1.3E-116 T 28-03-2018 IPR024169 Serine-pyruvate aminotransferase/2-aminoethylphosphonate-pyruvate transaminase KEGG: 00440+2.6.1.37|MetaCyc: PWY-6832|Reactome: R-HSA-389661 CO689_RS09085 35560a4e6a168782ebecb2adb1daaabd 298 SUPERFAMILY SSF82549 1 283 9.68E-85 T 28-03-2018 CO689_RS09085 35560a4e6a168782ebecb2adb1daaabd 298 Gene3D G3DSA:3.30.1180.10 153 286 4.9E-35 T 28-03-2018 CO689_RS09085 35560a4e6a168782ebecb2adb1daaabd 298 Gene3D G3DSA:2.20.28.50 31 53 1.2E-9 T 28-03-2018 CO689_RS09085 35560a4e6a168782ebecb2adb1daaabd 298 Pfam PF02645 Uncharacterised protein, DegV family COG1307 2 281 1.5E-83 T 28-03-2018 IPR003797 DegV CO689_RS09085 35560a4e6a168782ebecb2adb1daaabd 298 Gene3D G3DSA:3.40.50.10440 1 30 4.4E-4 T 28-03-2018 CO689_RS09085 35560a4e6a168782ebecb2adb1daaabd 298 TIGRFAM TIGR00762 DegV: EDD domain protein, DegV family 3 280 4.2E-95 T 28-03-2018 IPR003797 DegV CO689_RS09085 35560a4e6a168782ebecb2adb1daaabd 298 Gene3D G3DSA:3.40.50.10440 54 152 2.2E-30 T 28-03-2018 CO689_RS13210 20513e109f2c17c8c69723de97485478 590 SMART SM00400 34 88 1.3E-36 T 28-03-2018 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 CO689_RS13210 20513e109f2c17c8c69723de97485478 590 SUPERFAMILY SSF56731 113 420 7.32E-94 T 28-03-2018 CO689_RS13210 20513e109f2c17c8c69723de97485478 590 TIGRFAM TIGR01391 dnaG: DNA primase 2 415 8.2E-150 T 28-03-2018 IPR006295 DNA primase, DnaG GO:0003896|GO:0006269 CO689_RS13210 20513e109f2c17c8c69723de97485478 590 Pfam PF00772 DnaB-like helicase N terminal domain 452 546 2.0E-7 T 28-03-2018 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 CO689_RS13210 20513e109f2c17c8c69723de97485478 590 Pfam PF13662 Toprim domain 258 333 1.1E-14 T 28-03-2018 IPR006171 TOPRIM domain CO689_RS13210 20513e109f2c17c8c69723de97485478 590 SMART SM00493 258 329 1.4E-15 T 28-03-2018 IPR006171 TOPRIM domain CO689_RS13210 20513e109f2c17c8c69723de97485478 590 Gene3D G3DSA:3.90.980.10 107 239 5.6E-41 T 28-03-2018 IPR013264 DNA primase, catalytic core, N-terminal CO689_RS13210 20513e109f2c17c8c69723de97485478 590 Gene3D G3DSA:3.40.1360.10 240 364 2.9E-33 T 28-03-2018 CO689_RS13210 20513e109f2c17c8c69723de97485478 590 Gene3D G3DSA:1.10.860.10 452 549 3.5E-10 T 28-03-2018 IPR016136 DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal CO689_RS13210 20513e109f2c17c8c69723de97485478 590 PIRSF PIRSF002811 1 589 1.3E-186 T 28-03-2018 IPR030846 DNA primase DnaG, bacteria GO:0003896|GO:0006269|GO:0008270 CO689_RS13210 20513e109f2c17c8c69723de97485478 590 SUPERFAMILY SSF48024 453 548 2.62E-9 T 28-03-2018 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 CO689_RS13210 20513e109f2c17c8c69723de97485478 590 Pfam PF01807 CHC2 zinc finger 4 97 6.0E-38 T 28-03-2018 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 CO689_RS13210 20513e109f2c17c8c69723de97485478 590 Hamap MF_00974 DNA primase [dnaG]. 2 579 27.909 T 28-03-2018 IPR030846 DNA primase DnaG, bacteria GO:0003896|GO:0006269|GO:0008270 CO689_RS13210 20513e109f2c17c8c69723de97485478 590 Pfam PF08275 DNA primase catalytic core, N-terminal domain 125 251 5.2E-40 T 28-03-2018 IPR013264 DNA primase, catalytic core, N-terminal CO689_RS13210 20513e109f2c17c8c69723de97485478 590 Gene3D G3DSA:3.90.580.10 1 100 8.2E-34 T 28-03-2018 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 CO689_RS13210 20513e109f2c17c8c69723de97485478 590 SUPERFAMILY SSF57783 2 96 3.57E-35 T 28-03-2018 CO689_RS04165 3d8e034e84550d983dababed9c362d58 545 Pfam PF13520 Amino acid permease 9 429 8.0E-41 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CO689_RS04165 3d8e034e84550d983dababed9c362d58 545 PIRSF PIRSF006060 1 538 5.4E-59 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CO689_RS01630 64c2a2c7db18898a106189250d2bb66e 578 SMART SM00382 366 552 6.4E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain CO689_RS01630 64c2a2c7db18898a106189250d2bb66e 578 SUPERFAMILY SSF90123 4 328 3.27E-83 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CO689_RS01630 64c2a2c7db18898a106189250d2bb66e 578 SUPERFAMILY SSF52540 332 576 6.69E-96 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CO689_RS01630 64c2a2c7db18898a106189250d2bb66e 578 ProSitePatterns PS00211 ABC transporters family signature. 478 492 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CO689_RS01630 64c2a2c7db18898a106189250d2bb66e 578 Gene3D G3DSA:3.40.50.300 328 577 7.5E-78 T 28-03-2018 CO689_RS01630 64c2a2c7db18898a106189250d2bb66e 578 Gene3D G3DSA:1.20.1560.10 1 327 2.9E-70 T 28-03-2018 CO689_RS01630 64c2a2c7db18898a106189250d2bb66e 578 Pfam PF00005 ABC transporter 357 506 7.8E-33 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CO689_RS01630 64c2a2c7db18898a106189250d2bb66e 578 Pfam PF00664 ABC transporter transmembrane region 19 294 6.2E-49 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CO689_RS03390 93b8d8fc532743d2b22d4c414503a57f 100 Hamap MF_00739 Urease subunit gamma [ureA]. 1 100 32.785 T 28-03-2018 IPR012010 Urease, gamma subunit GO:0009039|GO:0019627 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CO689_RS03390 93b8d8fc532743d2b22d4c414503a57f 100 Gene3D G3DSA:3.30.280.10 2 99 4.9E-45 T 28-03-2018 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CO689_RS03390 93b8d8fc532743d2b22d4c414503a57f 100 ProDom PD002319 SUBUNIT GAMMA HYDROLASE UREASE UREA AMIDOHYDROLASE UREASE ALPHA GAMMA/BETA METAL-BINDING 9 99 3.0E-42 T 28-03-2018 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CO689_RS03390 93b8d8fc532743d2b22d4c414503a57f 100 Pfam PF00547 Urease, gamma subunit 2 99 4.7E-44 T 28-03-2018 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CO689_RS03390 93b8d8fc532743d2b22d4c414503a57f 100 SUPERFAMILY SSF54111 2 99 8.5E-44 T 28-03-2018 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CO689_RS03390 93b8d8fc532743d2b22d4c414503a57f 100 TIGRFAM TIGR00193 urease_gam: urease, gamma subunit 2 99 6.2E-46 T 28-03-2018 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CO689_RS03390 93b8d8fc532743d2b22d4c414503a57f 100 PIRSF PIRSF001223 1 100 1.2E-49 T 28-03-2018 IPR012010 Urease, gamma subunit GO:0009039|GO:0019627 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CO689_RS13770 76a16b7dba8fd568be61d5aa437ef2ef 647 SUPERFAMILY SSF55681 242 531 5.97E-97 T 28-03-2018 CO689_RS13770 76a16b7dba8fd568be61d5aa437ef2ef 647 Gene3D G3DSA:3.30.930.10 220 537 5.0E-108 T 28-03-2018 CO689_RS13770 76a16b7dba8fd568be61d5aa437ef2ef 647 SUPERFAMILY SSF52954 536 639 4.68E-34 T 28-03-2018 IPR004154 Anticodon-binding CO689_RS13770 76a16b7dba8fd568be61d5aa437ef2ef 647 Gene3D G3DSA:3.40.50.800 538 647 5.5E-31 T 28-03-2018 IPR004154 Anticodon-binding CO689_RS13770 76a16b7dba8fd568be61d5aa437ef2ef 647 SMART SM00863 169 218 3.2E-25 T 28-03-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 CO689_RS13770 76a16b7dba8fd568be61d5aa437ef2ef 647 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 324 534 5.1E-34 T 28-03-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 CO689_RS13770 76a16b7dba8fd568be61d5aa437ef2ef 647 Hamap MF_00184 Threonine--tRNA ligase [thrS]. 68 641 35.114 T 28-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 CO689_RS13770 76a16b7dba8fd568be61d5aa437ef2ef 647 Gene3D G3DSA:3.30.54.20 147 186 7.7E-20 T 28-03-2018 CO689_RS13770 76a16b7dba8fd568be61d5aa437ef2ef 647 Gene3D G3DSA:3.30.980.10 67 146 5.0E-27 T 28-03-2018 CO689_RS13770 76a16b7dba8fd568be61d5aa437ef2ef 647 Pfam PF03129 Anticodon binding domain 547 632 3.1E-25 T 28-03-2018 IPR004154 Anticodon-binding CO689_RS13770 76a16b7dba8fd568be61d5aa437ef2ef 647 TIGRFAM TIGR00418 thrS: threonine--tRNA ligase 74 637 4.4E-241 T 28-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 CO689_RS13770 76a16b7dba8fd568be61d5aa437ef2ef 647 PRINTS PR01047 Threonyl-tRNA synthetase signature 470 498 4.0E-47 T 28-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 CO689_RS13770 76a16b7dba8fd568be61d5aa437ef2ef 647 PRINTS PR01047 Threonyl-tRNA synthetase signature 513 526 4.0E-47 T 28-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 CO689_RS13770 76a16b7dba8fd568be61d5aa437ef2ef 647 PRINTS PR01047 Threonyl-tRNA synthetase signature 540 552 4.0E-47 T 28-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 CO689_RS13770 76a16b7dba8fd568be61d5aa437ef2ef 647 PRINTS PR01047 Threonyl-tRNA synthetase signature 331 359 4.0E-47 T 28-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 CO689_RS13770 76a16b7dba8fd568be61d5aa437ef2ef 647 PRINTS PR01047 Threonyl-tRNA synthetase signature 364 387 4.0E-47 T 28-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 CO689_RS13770 76a16b7dba8fd568be61d5aa437ef2ef 647 SUPERFAMILY SSF55186 66 240 5.76E-68 T 28-03-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain GO:0000166 CO689_RS13770 76a16b7dba8fd568be61d5aa437ef2ef 647 Gene3D G3DSA:3.10.20.30 1 64 1.4E-21 T 28-03-2018 IPR012675 Beta-grasp domain CO689_RS13770 76a16b7dba8fd568be61d5aa437ef2ef 647 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 169 218 6.3E-17 T 28-03-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 CO689_RS13770 76a16b7dba8fd568be61d5aa437ef2ef 647 SUPERFAMILY SSF81271 4 63 6.32E-17 T 28-03-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 CO689_RS13770 76a16b7dba8fd568be61d5aa437ef2ef 647 Pfam PF02824 TGS domain 5 63 8.5E-14 T 28-03-2018 IPR004095 TGS KEGG: 00970+6.1.1.3 CO689_RS12355 77b17aa0715881af2a22a8cc91a43788 250 TIGRFAM TIGR00262 trpA: tryptophan synthase, alpha subunit 15 239 1.5E-56 T 28-03-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 CO689_RS12355 77b17aa0715881af2a22a8cc91a43788 250 Hamap MF_00131 Tryptophan synthase alpha chain [trpA]. 1 247 26.332 T 28-03-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 CO689_RS12355 77b17aa0715881af2a22a8cc91a43788 250 ProSitePatterns PS00167 Tryptophan synthase alpha chain signature. 30 43 - T 28-03-2018 IPR018204 Tryptophan synthase, alpha chain, active site GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 CO689_RS12355 77b17aa0715881af2a22a8cc91a43788 250 Pfam PF00290 Tryptophan synthase alpha chain 3 230 1.1E-68 T 28-03-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 CO689_RS12355 77b17aa0715881af2a22a8cc91a43788 250 Gene3D G3DSA:3.20.20.70 1 250 1.8E-59 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CO689_RS12355 77b17aa0715881af2a22a8cc91a43788 250 SUPERFAMILY SSF51366 3 238 1.65E-68 T 28-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 CO689_RS04460 66cb64e59c8f7c407c4040c1443f4d84 276 Gene3D G3DSA:3.40.50.1820 4 275 3.3E-28 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CO689_RS04460 66cb64e59c8f7c407c4040c1443f4d84 276 SUPERFAMILY SSF53474 10 133 2.54E-26 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CO689_RS04460 66cb64e59c8f7c407c4040c1443f4d84 276 SUPERFAMILY SSF53474 180 270 2.54E-26 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CO689_RS04460 66cb64e59c8f7c407c4040c1443f4d84 276 Pfam PF07859 alpha/beta hydrolase fold 33 222 1.2E-11 T 28-03-2018 IPR013094 Alpha/beta hydrolase fold-3 GO:0008152|GO:0016787 CO689_RS07435 26835749f9d17ef59f1476c7ed467dde 335 SUPERFAMILY SSF54106 28 71 4.58E-12 T 28-03-2018 IPR018392 LysM domain CO689_RS07435 26835749f9d17ef59f1476c7ed467dde 335 SUPERFAMILY SSF54106 93 135 9.42E-12 T 28-03-2018 IPR018392 LysM domain CO689_RS07435 26835749f9d17ef59f1476c7ed467dde 335 SUPERFAMILY SSF54106 156 198 7.19E-12 T 28-03-2018 IPR018392 LysM domain CO689_RS07435 26835749f9d17ef59f1476c7ed467dde 335 Gene3D G3DSA:3.10.350.10 23 84 3.1E-18 T 28-03-2018 CO689_RS07435 26835749f9d17ef59f1476c7ed467dde 335 Gene3D G3DSA:3.10.350.10 153 214 2.7E-16 T 28-03-2018 CO689_RS07435 26835749f9d17ef59f1476c7ed467dde 335 Pfam PF01476 LysM domain 94 135 2.4E-14 T 28-03-2018 IPR018392 LysM domain CO689_RS07435 26835749f9d17ef59f1476c7ed467dde 335 Pfam PF01476 LysM domain 157 198 1.3E-15 T 28-03-2018 IPR018392 LysM domain CO689_RS07435 26835749f9d17ef59f1476c7ed467dde 335 Pfam PF01476 LysM domain 30 71 1.4E-14 T 28-03-2018 IPR018392 LysM domain CO689_RS07435 26835749f9d17ef59f1476c7ed467dde 335 Gene3D G3DSA:3.10.350.10 85 152 1.0E-18 T 28-03-2018 CO689_RS07435 26835749f9d17ef59f1476c7ed467dde 335 SMART SM00257 93 136 6.2E-16 T 28-03-2018 IPR018392 LysM domain CO689_RS07435 26835749f9d17ef59f1476c7ed467dde 335 SMART SM00257 29 72 1.5E-16 T 28-03-2018 IPR018392 LysM domain CO689_RS07435 26835749f9d17ef59f1476c7ed467dde 335 SMART SM00257 156 199 3.5E-16 T 28-03-2018 IPR018392 LysM domain CO689_RS07435 26835749f9d17ef59f1476c7ed467dde 335 SUPERFAMILY SSF54001 219 334 5.1E-17 T 28-03-2018 CO689_RS07435 26835749f9d17ef59f1476c7ed467dde 335 Pfam PF05257 CHAP domain 229 310 1.3E-13 T 28-03-2018 IPR007921 CHAP domain CO689_RS04730 35724ed538017c3aafb77e9e48ca2cbf 335 Pfam PF00294 pfkB family carbohydrate kinase 5 302 1.8E-31 T 28-03-2018 IPR011611 Carbohydrate kinase PfkB CO689_RS04730 35724ed538017c3aafb77e9e48ca2cbf 335 SUPERFAMILY SSF53613 1 322 2.03E-66 T 28-03-2018 IPR029056 Ribokinase-like CO689_RS04730 35724ed538017c3aafb77e9e48ca2cbf 335 Gene3D G3DSA:3.40.1190.20 2 323 1.4E-47 T 28-03-2018 IPR029056 Ribokinase-like CO689_RS06270 a52bcb4379228c8120b29b144168beab 465 Pfam PF13520 Amino acid permease 12 426 1.9E-44 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CO689_RS06270 a52bcb4379228c8120b29b144168beab 465 PIRSF PIRSF006060 1 464 7.2E-92 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CO689_RS11300 7e036189f573e4f9f2abe2fd30adc98d 305 SUPERFAMILY SSF55120 74 300 2.72E-78 T 28-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 CO689_RS11300 7e036189f573e4f9f2abe2fd30adc98d 305 Pfam PF01479 S4 domain 16 62 1.8E-11 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CO689_RS11300 7e036189f573e4f9f2abe2fd30adc98d 305 TIGRFAM TIGR00005 rluA_subfam: pseudouridine synthase, RluA family 12 300 5.1E-101 T 28-03-2018 IPR006225 Pseudouridine synthase, RluC/RluD GO:0001522|GO:0003723|GO:0009451|GO:0009982 CO689_RS11300 7e036189f573e4f9f2abe2fd30adc98d 305 Gene3D G3DSA:3.30.2350.10 80 304 8.2E-71 T 28-03-2018 CO689_RS11300 7e036189f573e4f9f2abe2fd30adc98d 305 Pfam PF00849 RNA pseudouridylate synthase 90 242 5.4E-35 T 28-03-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 CO689_RS11300 7e036189f573e4f9f2abe2fd30adc98d 305 SUPERFAMILY SSF55174 14 114 8.37E-16 T 28-03-2018 CO689_RS11300 7e036189f573e4f9f2abe2fd30adc98d 305 Gene3D G3DSA:3.10.290.10 1 73 2.5E-17 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CO689_RS11300 7e036189f573e4f9f2abe2fd30adc98d 305 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 135 149 - T 28-03-2018 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 CO689_RS11300 7e036189f573e4f9f2abe2fd30adc98d 305 SMART SM00363 16 75 2.8E-12 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CO689_RS01755 8c786399a6b284c0a62ba8a88d2bc7b3 239 SUPERFAMILY SSF52317 16 189 5.02E-21 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CO689_RS01755 8c786399a6b284c0a62ba8a88d2bc7b3 239 Gene3D G3DSA:3.40.50.880 11 173 1.4E-15 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CO689_RS01755 8c786399a6b284c0a62ba8a88d2bc7b3 239 Pfam PF07685 CobB/CobQ-like glutamine amidotransferase domain 8 196 2.8E-42 T 28-03-2018 IPR011698 CobB/CobQ-like glutamine amidotransferase GO:0003824|GO:0009236 CO689_RS06815 350b18d8eb02096143184d84b7a15b93 542 Pfam PF00239 Resolvase, N terminal domain 11 156 2.0E-40 T 28-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CO689_RS06815 350b18d8eb02096143184d84b7a15b93 542 Pfam PF07508 Recombinase 180 281 8.3E-25 T 28-03-2018 IPR011109 DNA-binding recombinase domain GO:0000150|GO:0003677 CO689_RS06815 350b18d8eb02096143184d84b7a15b93 542 SMART SM00857 9 157 2.1E-59 T 28-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CO689_RS06815 350b18d8eb02096143184d84b7a15b93 542 Gene3D G3DSA:3.30.65.10 279 345 5.6E-4 T 28-03-2018 CO689_RS06815 350b18d8eb02096143184d84b7a15b93 542 ProSitePatterns PS00397 Site-specific recombinases active site. 12 20 - T 28-03-2018 IPR006118 Recombinase, conserved site GO:0000150|GO:0006310 CO689_RS06815 350b18d8eb02096143184d84b7a15b93 542 Gene3D G3DSA:3.40.50.1390 2 126 1.6E-43 T 28-03-2018 CO689_RS06815 350b18d8eb02096143184d84b7a15b93 542 Pfam PF04606 Ogr/Delta-like zinc finger 301 356 1.0E-17 T 28-03-2018 IPR007684 Zinc finger, Ogr/Delta-type CO689_RS06815 350b18d8eb02096143184d84b7a15b93 542 SUPERFAMILY SSF53041 8 157 2.62E-38 T 28-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CO689_RS06815 350b18d8eb02096143184d84b7a15b93 542 Gene3D G3DSA:1.20.5.40 127 155 1.8E-9 T 28-03-2018 CO689_RS06815 350b18d8eb02096143184d84b7a15b93 542 Gene3D G3DSA:1.20.120.570 346 482 2.5E-5 T 28-03-2018 CO689_RS09345 425f4b84d992fd918ca817b2c4c5df8b 434 TIGRFAM TIGR01060 eno: phosphopyruvate hydratase 4 431 3.1E-207 T 28-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CO689_RS09345 425f4b84d992fd918ca817b2c4c5df8b 434 Hamap MF_00318 Enolase [eno]. 2 417 44.438 T 28-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CO689_RS09345 425f4b84d992fd918ca817b2c4c5df8b 434 Pfam PF03952 Enolase, N-terminal domain 4 136 3.4E-61 T 28-03-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CO689_RS09345 425f4b84d992fd918ca817b2c4c5df8b 434 SUPERFAMILY SSF51604 142 431 5.8E-125 T 28-03-2018 IPR029065 Enolase C-terminal domain-like CO689_RS09345 425f4b84d992fd918ca817b2c4c5df8b 434 SMART SM01193 4 136 1.7E-97 T 28-03-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CO689_RS09345 425f4b84d992fd918ca817b2c4c5df8b 434 Pfam PF00113 Enolase, C-terminal TIM barrel domain 143 429 6.2E-128 T 28-03-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CO689_RS09345 425f4b84d992fd918ca817b2c4c5df8b 434 PRINTS PR00148 Enolase signature 37 51 2.8E-48 T 28-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CO689_RS09345 425f4b84d992fd918ca817b2c4c5df8b 434 PRINTS PR00148 Enolase signature 109 125 2.8E-48 T 28-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CO689_RS09345 425f4b84d992fd918ca817b2c4c5df8b 434 PRINTS PR00148 Enolase signature 317 328 2.8E-48 T 28-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CO689_RS09345 425f4b84d992fd918ca817b2c4c5df8b 434 PRINTS PR00148 Enolase signature 369 386 2.8E-48 T 28-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CO689_RS09345 425f4b84d992fd918ca817b2c4c5df8b 434 PRINTS PR00148 Enolase signature 340 354 2.8E-48 T 28-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CO689_RS09345 425f4b84d992fd918ca817b2c4c5df8b 434 PRINTS PR00148 Enolase signature 163 176 2.8E-48 T 28-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CO689_RS09345 425f4b84d992fd918ca817b2c4c5df8b 434 ProSitePatterns PS00164 Enolase signature. 340 353 - T 28-03-2018 IPR020809 Enolase, conserved site KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CO689_RS09345 425f4b84d992fd918ca817b2c4c5df8b 434 Gene3D G3DSA:3.20.20.120 130 434 1.1E-98 T 28-03-2018 IPR029065 Enolase C-terminal domain-like CO689_RS09345 425f4b84d992fd918ca817b2c4c5df8b 434 PIRSF PIRSF001400 1 431 6.1E-186 T 28-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CO689_RS09345 425f4b84d992fd918ca817b2c4c5df8b 434 SUPERFAMILY SSF54826 4 139 1.08E-58 T 28-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CO689_RS09345 425f4b84d992fd918ca817b2c4c5df8b 434 SMART SM01192 141 431 3.2E-211 T 28-03-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CO689_RS09345 425f4b84d992fd918ca817b2c4c5df8b 434 Gene3D G3DSA:3.30.390.10 3 127 4.7E-54 T 28-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CO689_RS00995 14659256590046e4932e2cd5b769cbf3 1180 Pfam PF09397 Ftsk gamma domain 1113 1172 2.8E-26 T 28-03-2018 IPR018541 FtsK gamma domain CO689_RS00995 14659256590046e4932e2cd5b769cbf3 1180 Gene3D G3DSA:1.10.10.10 1112 1166 1.2E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS00995 14659256590046e4932e2cd5b769cbf3 1180 SUPERFAMILY SSF52540 801 1089 2.52E-46 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CO689_RS00995 14659256590046e4932e2cd5b769cbf3 1180 SMART SM00843 1110 1175 5.4E-33 T 28-03-2018 IPR018541 FtsK gamma domain CO689_RS00995 14659256590046e4932e2cd5b769cbf3 1180 Pfam PF01580 FtsK/SpoIIIE family 966 1016 5.9E-14 T 28-03-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 CO689_RS00995 14659256590046e4932e2cd5b769cbf3 1180 Pfam PF01580 FtsK/SpoIIIE family 828 962 4.7E-45 T 28-03-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 CO689_RS00995 14659256590046e4932e2cd5b769cbf3 1180 Gene3D G3DSA:3.40.50.300 616 1055 8.8E-50 T 28-03-2018 CO689_RS00995 14659256590046e4932e2cd5b769cbf3 1180 SUPERFAMILY SSF46785 1111 1174 1.58E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS08910 4709b3cbc461a20367f69ee427dafd87 203 SUPERFAMILY SSF56752 4 199 3.01E-31 T 28-03-2018 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 CO689_RS08910 4709b3cbc461a20367f69ee427dafd87 203 Pfam PF01063 Amino-transferase class IV 4 199 1.7E-27 T 28-03-2018 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 CO689_RS08910 4709b3cbc461a20367f69ee427dafd87 203 Gene3D G3DSA:3.30.470.10 2 66 1.1E-13 T 28-03-2018 CO689_RS08910 4709b3cbc461a20367f69ee427dafd87 203 Gene3D G3DSA:3.20.10.10 67 203 4.0E-19 T 28-03-2018 CO689_RS00545 e3cc96b5b0364cc78fcfd5d09abcbcbc 139 SUPERFAMILY SSF46689 10 75 4.39E-13 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CO689_RS00545 e3cc96b5b0364cc78fcfd5d09abcbcbc 139 Pfam PF00440 Bacterial regulatory proteins, tetR family 23 62 7.3E-6 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CO689_RS00545 e3cc96b5b0364cc78fcfd5d09abcbcbc 139 Gene3D G3DSA:1.10.10.60 53 116 4.8E-6 T 28-03-2018 CO689_RS00545 e3cc96b5b0364cc78fcfd5d09abcbcbc 139 Gene3D G3DSA:1.10.10.60 12 52 2.2E-10 T 28-03-2018 CO689_RS02485 a515027a0ddb73b77eff8ff295015a81 383 Gene3D G3DSA:3.40.50.2000 203 348 1.2E-36 T 28-03-2018 CO689_RS02485 a515027a0ddb73b77eff8ff295015a81 383 Pfam PF02350 UDP-N-acetylglucosamine 2-epimerase 23 362 3.5E-120 T 28-03-2018 IPR003331 UDP-N-acetylglucosamine 2-epimerase domain Reactome: R-HSA-4085001 CO689_RS02485 a515027a0ddb73b77eff8ff295015a81 383 SUPERFAMILY SSF53756 2 369 1.0E-134 T 28-03-2018 CO689_RS02485 a515027a0ddb73b77eff8ff295015a81 383 TIGRFAM TIGR00236 wecB: UDP-N-acetylglucosamine 2-epimerase 3 364 2.6E-158 T 28-03-2018 IPR029767 UDP-N-acetylglucosamine 2-epimerase WecB-like GO:0008761 CO689_RS02485 a515027a0ddb73b77eff8ff295015a81 383 Gene3D G3DSA:3.40.50.2000 2 202 1.1E-78 T 28-03-2018 CO689_RS12785 a073e02da853f5cb8cefa2027581d3c9 318 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 200 212 - T 28-03-2018 IPR033749 Polyprenyl synthetase, conserved site CO689_RS12785 a073e02da853f5cb8cefa2027581d3c9 318 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 78 92 - T 28-03-2018 IPR033749 Polyprenyl synthetase, conserved site CO689_RS12785 a073e02da853f5cb8cefa2027581d3c9 318 Pfam PF00348 Polyprenyl synthetase 27 258 1.3E-65 T 28-03-2018 IPR000092 Polyprenyl synthetase GO:0008299 CO689_RS12785 a073e02da853f5cb8cefa2027581d3c9 318 SUPERFAMILY SSF48576 7 317 1.13E-81 T 28-03-2018 IPR008949 Isoprenoid synthase domain CO689_RS12785 a073e02da853f5cb8cefa2027581d3c9 318 Gene3D G3DSA:1.10.600.10 3 318 1.5E-87 T 28-03-2018 IPR008949 Isoprenoid synthase domain CO689_RS13370 f88a645df06f1503bcc409023b283f38 96 SUPERFAMILY SSF75471 1 94 5.1E-31 T 28-03-2018 IPR001890 RNA-binding, CRM domain GO:0003723 CO689_RS13370 f88a645df06f1503bcc409023b283f38 96 ProDom PD010559 RNA-BINDING YHBY UPF0044 PREDICTED RNA RIBOSOMAL CONTAINING KH BINDING DOMAIN 8 96 3.0E-35 T 28-03-2018 IPR001890 RNA-binding, CRM domain GO:0003723 CO689_RS13370 f88a645df06f1503bcc409023b283f38 96 TIGRFAM TIGR00253 RNA_bind_YhbY: putative RNA-binding protein, YhbY family 2 96 1.3E-37 T 28-03-2018 IPR017924 RNA-binding protein YhbY GO:0003723 CO689_RS13370 f88a645df06f1503bcc409023b283f38 96 SMART SM01103 2 85 1.0E-41 T 28-03-2018 IPR001890 RNA-binding, CRM domain GO:0003723 CO689_RS13370 f88a645df06f1503bcc409023b283f38 96 Gene3D G3DSA:3.30.110.60 1 96 2.7E-28 T 28-03-2018 IPR001890 RNA-binding, CRM domain GO:0003723 CO689_RS13370 f88a645df06f1503bcc409023b283f38 96 Pfam PF01985 CRS1 / YhbY (CRM) domain 2 85 2.7E-22 T 28-03-2018 IPR001890 RNA-binding, CRM domain GO:0003723 CO689_RS11060 be2f37a4372f36cb2f50d56ce27f3f96 317 PIRSF PIRSF037748 1 311 1.5E-101 T 28-03-2018 IPR004641 Ribonuclease HIII GO:0004523|GO:0005737|GO:0016070 CO689_RS11060 be2f37a4372f36cb2f50d56ce27f3f96 317 SUPERFAMILY SSF53098 96 311 3.03E-47 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CO689_RS11060 be2f37a4372f36cb2f50d56ce27f3f96 317 Hamap MF_00053 Ribonuclease HIII [rnhC]. 1 310 27.599 T 28-03-2018 IPR004641 Ribonuclease HIII GO:0004523|GO:0005737|GO:0016070 CO689_RS11060 be2f37a4372f36cb2f50d56ce27f3f96 317 Pfam PF11858 Domain of unknown function (DUF3378) 3 75 1.7E-18 T 28-03-2018 IPR024568 Ribonuclease HIII, N-terminal CO689_RS11060 be2f37a4372f36cb2f50d56ce27f3f96 317 Pfam PF01351 Ribonuclease HII 97 302 1.0E-38 T 28-03-2018 IPR024567 Ribonuclease HII/HIII domain CO689_RS11060 be2f37a4372f36cb2f50d56ce27f3f96 317 Gene3D G3DSA:3.30.420.10 71 316 2.4E-39 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CO689_RS11060 be2f37a4372f36cb2f50d56ce27f3f96 317 TIGRFAM TIGR00716 rnhC: ribonuclease HIII 11 302 3.2E-60 T 28-03-2018 IPR004641 Ribonuclease HIII GO:0004523|GO:0005737|GO:0016070 CO689_RS01095 7716bc309cad56b2b212066c431a2c04 318 TIGRFAM TIGR01771 L-LDH-NAD: L-lactate dehydrogenase 11 308 1.2E-124 T 28-03-2018 IPR011304 L-lactate dehydrogenase GO:0004459|GO:0005737|GO:0055114 KEGG: 00010+1.1.1.27|KEGG: 00270+1.1.1.27|KEGG: 00620+1.1.1.27|KEGG: 00640+1.1.1.27|MetaCyc: PWY-5481|MetaCyc: PWY-6901|Reactome: R-HSA-70268 CO689_RS01095 7716bc309cad56b2b212066c431a2c04 318 ProSitePatterns PS00064 L-lactate dehydrogenase active site. 176 182 - T 28-03-2018 IPR018177 L-lactate dehydrogenase, active site GO:0004459|GO:0055114 KEGG: 00010+1.1.1.27|KEGG: 00270+1.1.1.27|KEGG: 00620+1.1.1.27|KEGG: 00640+1.1.1.27|MetaCyc: PWY-5481|MetaCyc: PWY-6901|Reactome: R-HSA-70268 CO689_RS01095 7716bc309cad56b2b212066c431a2c04 318 PIRSF PIRSF000102 3 317 7.6E-108 T 28-03-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 CO689_RS01095 7716bc309cad56b2b212066c431a2c04 318 Pfam PF00056 lactate/malate dehydrogenase, NAD binding domain 8 146 4.4E-47 T 28-03-2018 IPR001236 Lactate/malate dehydrogenase, N-terminal GO:0016491|GO:0055114 CO689_RS01095 7716bc309cad56b2b212066c431a2c04 318 SUPERFAMILY SSF56327 147 313 1.59E-52 T 28-03-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 CO689_RS01095 7716bc309cad56b2b212066c431a2c04 318 Gene3D G3DSA:3.40.50.720 8 148 6.0E-35 T 28-03-2018 CO689_RS01095 7716bc309cad56b2b212066c431a2c04 318 PRINTS PR00086 L-lactate dehydrogenase signature 174 187 5.8E-46 T 28-03-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 CO689_RS01095 7716bc309cad56b2b212066c431a2c04 318 PRINTS PR00086 L-lactate dehydrogenase signature 8 32 5.8E-46 T 28-03-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 CO689_RS01095 7716bc309cad56b2b212066c431a2c04 318 PRINTS PR00086 L-lactate dehydrogenase signature 144 162 5.8E-46 T 28-03-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 CO689_RS01095 7716bc309cad56b2b212066c431a2c04 318 PRINTS PR00086 L-lactate dehydrogenase signature 120 140 5.8E-46 T 28-03-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 CO689_RS01095 7716bc309cad56b2b212066c431a2c04 318 PRINTS PR00086 L-lactate dehydrogenase signature 33 57 5.8E-46 T 28-03-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 CO689_RS01095 7716bc309cad56b2b212066c431a2c04 318 Pfam PF02866 lactate/malate dehydrogenase, alpha/beta C-terminal domain 149 312 1.7E-31 T 28-03-2018 IPR022383 Lactate/malate dehydrogenase, C-terminal GO:0016616|GO:0055114 CO689_RS01095 7716bc309cad56b2b212066c431a2c04 318 Gene3D G3DSA:3.90.110.10 149 313 1.3E-41 T 28-03-2018 CO689_RS01095 7716bc309cad56b2b212066c431a2c04 318 SUPERFAMILY SSF51735 3 146 5.58E-55 T 28-03-2018 IPR016040 NAD(P)-binding domain CO689_RS01095 7716bc309cad56b2b212066c431a2c04 318 Hamap MF_00488 L-lactate dehydrogenase [ldh]. 6 314 44.951 T 28-03-2018 IPR011304 L-lactate dehydrogenase GO:0004459|GO:0005737|GO:0055114 KEGG: 00010+1.1.1.27|KEGG: 00270+1.1.1.27|KEGG: 00620+1.1.1.27|KEGG: 00640+1.1.1.27|MetaCyc: PWY-5481|MetaCyc: PWY-6901|Reactome: R-HSA-70268 CO689_RS07055 e3fe37eb587656d5f80723c913163220 280 Gene3D G3DSA:1.10.10.730 122 169 1.4E-20 T 28-03-2018 CO689_RS07055 e3fe37eb587656d5f80723c913163220 280 TIGRFAM TIGR04285 nucleoid_noc: nucleoid occlusion protein 30 279 3.6E-98 T 28-03-2018 IPR023705 Nucleoid occlusion protein CO689_RS07055 e3fe37eb587656d5f80723c913163220 280 SUPERFAMILY SSF109709 114 220 4.18E-33 T 28-03-2018 CO689_RS07055 e3fe37eb587656d5f80723c913163220 280 TIGRFAM TIGR00180 parB_part: ParB/RepB/Spo0J family partition protein 29 206 1.1E-56 T 28-03-2018 IPR004437 ParB/RepB/Spo0J partition protein family GO:0003677 CO689_RS07055 e3fe37eb587656d5f80723c913163220 280 SUPERFAMILY SSF110849 31 123 2.14E-28 T 28-03-2018 IPR003115 ParB/Sulfiredoxin CO689_RS07055 e3fe37eb587656d5f80723c913163220 280 SMART SM00470 31 121 1.7E-32 T 28-03-2018 IPR003115 ParB/Sulfiredoxin CO689_RS07055 e3fe37eb587656d5f80723c913163220 280 Pfam PF02195 ParB-like nuclease domain 32 121 2.0E-25 T 28-03-2018 IPR003115 ParB/Sulfiredoxin CO689_RS07055 e3fe37eb587656d5f80723c913163220 280 Gene3D G3DSA:3.90.1530.10 18 121 1.1E-35 T 28-03-2018 CO689_RS04250 4edae60b8bdfc42971e38e1dd88f16ad 399 SUPERFAMILY SSF52540 3 311 1.17E-41 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CO689_RS04250 4edae60b8bdfc42971e38e1dd88f16ad 399 SMART SM00833 260 375 2.9E-45 T 28-03-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal CO689_RS04250 4edae60b8bdfc42971e38e1dd88f16ad 399 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 5 210 1.8E-59 T 28-03-2018 IPR003495 CobW/HypB/UreG, nucleotide-binding domain CO689_RS04250 4edae60b8bdfc42971e38e1dd88f16ad 399 Gene3D G3DSA:3.40.50.300 1 229 3.7E-51 T 28-03-2018 CO689_RS04250 4edae60b8bdfc42971e38e1dd88f16ad 399 Pfam PF07683 Cobalamin synthesis protein cobW C-terminal domain 260 375 1.3E-26 T 28-03-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal CO689_RS04250 4edae60b8bdfc42971e38e1dd88f16ad 399 Gene3D G3DSA:3.30.1220.10 240 376 1.6E-30 T 28-03-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal CO689_RS12245 592081fe440b84c6f51bf709bbc002c4 807 Gene3D G3DSA:3.30.1360.40 233 329 1.9E-32 T 28-03-2018 IPR024946 Arginine repressor C-terminal-like domain Reactome: R-HSA-4615885 CO689_RS12245 592081fe440b84c6f51bf709bbc002c4 807 SMART SM00434 8 461 4.2E-261 T 28-03-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CO689_RS12245 592081fe440b84c6f51bf709bbc002c4 807 TIGRFAM TIGR01061 parC_Gpos: DNA topoisomerase IV, A subunit 5 742 0.0 T 28-03-2018 IPR005741 DNA topoisomerase IV subunit A, Gram-positive GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 CO689_RS12245 592081fe440b84c6f51bf709bbc002c4 807 Pfam PF00521 DNA gyrase/topoisomerase IV, subunit A 29 468 5.2E-152 T 28-03-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CO689_RS12245 592081fe440b84c6f51bf709bbc002c4 807 Gene3D G3DSA:2.120.10.90 494 799 5.4E-69 T 28-03-2018 CO689_RS12245 592081fe440b84c6f51bf709bbc002c4 807 SUPERFAMILY SSF56719 28 483 8.5E-168 T 28-03-2018 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Reactome: R-HSA-4615885 CO689_RS12245 592081fe440b84c6f51bf709bbc002c4 807 Hamap MF_00937 DNA topoisomerase 4 subunit A [parC]. 4 800 32.396 T 28-03-2018 IPR005741 DNA topoisomerase IV subunit A, Gram-positive GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 CO689_RS12245 592081fe440b84c6f51bf709bbc002c4 807 SUPERFAMILY SSF101904 497 798 2.35E-79 T 28-03-2018 IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal CO689_RS12245 592081fe440b84c6f51bf709bbc002c4 807 Gene3D G3DSA:3.90.199.10 31 212 2.4E-76 T 28-03-2018 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 Reactome: R-HSA-4615885 CO689_RS12245 592081fe440b84c6f51bf709bbc002c4 807 Gene3D G3DSA:1.10.268.10 341 483 2.6E-47 T 28-03-2018 IPR013757 Type IIA DNA topoisomerase subunit A, alpha-helical domain GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CO689_RS12245 592081fe440b84c6f51bf709bbc002c4 807 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 550 594 3.5E-4 T 28-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 CO689_RS12245 592081fe440b84c6f51bf709bbc002c4 807 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 656 693 0.0034 T 28-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 CO689_RS12245 592081fe440b84c6f51bf709bbc002c4 807 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 703 750 0.34 T 28-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 CO689_RS12245 592081fe440b84c6f51bf709bbc002c4 807 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 606 648 3.0E-6 T 28-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 CO689_RS12245 592081fe440b84c6f51bf709bbc002c4 807 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 503 521 3.1 T 28-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 CO689_RS02365 0e4f66d35b52e02f6f3c477ac61879de 216 Gene3D G3DSA:1.10.3210.10 1 214 3.2E-22 T 28-03-2018 CO689_RS02365 0e4f66d35b52e02f6f3c477ac61879de 216 Pfam PF01966 HD domain 27 127 1.5E-6 T 28-03-2018 IPR006674 HD domain CO689_RS02365 0e4f66d35b52e02f6f3c477ac61879de 216 SMART SM00471 22 137 1.4E-7 T 28-03-2018 IPR003607 HD/PDEase domain CO689_RS02365 0e4f66d35b52e02f6f3c477ac61879de 216 SUPERFAMILY SSF109604 1 212 7.46E-66 T 28-03-2018 CO689_RS03520 2db6fc8e80c6c15e6e2b8bbfaadf8039 985 ProSitePatterns PS00551 Prokaryotic molybdopterin oxidoreductases signature 1. 262 279 - T 28-03-2018 IPR027467 Molybdopterin oxidoreductase, molybdopterin cofactor binding site GO:0051539 KEGG: 00910+1.7.99.4 CO689_RS03520 2db6fc8e80c6c15e6e2b8bbfaadf8039 985 Gene3D G3DSA:3.30.70.20 155 224 4.0E-11 T 28-03-2018 CO689_RS03520 2db6fc8e80c6c15e6e2b8bbfaadf8039 985 SUPERFAMILY SSF54292 6 74 1.06E-11 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CO689_RS03520 2db6fc8e80c6c15e6e2b8bbfaadf8039 985 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 190 201 - T 28-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CO689_RS03520 2db6fc8e80c6c15e6e2b8bbfaadf8039 985 Gene3D G3DSA:2.20.25.90 257 312 3.4E-19 T 28-03-2018 CO689_RS03520 2db6fc8e80c6c15e6e2b8bbfaadf8039 985 Pfam PF01568 Molydopterin dinucleotide binding domain 821 931 5.2E-20 T 28-03-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 CO689_RS03520 2db6fc8e80c6c15e6e2b8bbfaadf8039 985 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 258 311 2.1E-19 T 28-03-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CO689_RS03520 2db6fc8e80c6c15e6e2b8bbfaadf8039 985 SUPERFAMILY SSF53706 251 774 7.46E-188 T 28-03-2018 CO689_RS03520 2db6fc8e80c6c15e6e2b8bbfaadf8039 985 Pfam PF10588 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region 84 123 5.9E-10 T 28-03-2018 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CO689_RS03520 2db6fc8e80c6c15e6e2b8bbfaadf8039 985 SUPERFAMILY SSF54862 78 210 1.26E-26 T 28-03-2018 CO689_RS03520 2db6fc8e80c6c15e6e2b8bbfaadf8039 985 SMART SM00929 84 125 1.3E-11 T 28-03-2018 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CO689_RS03520 2db6fc8e80c6c15e6e2b8bbfaadf8039 985 Pfam PF00384 Molybdopterin oxidoreductase 314 736 4.9E-73 T 28-03-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CO689_RS03520 2db6fc8e80c6c15e6e2b8bbfaadf8039 985 Gene3D G3DSA:3.40.50.740 315 482 2.2E-34 T 28-03-2018 CO689_RS03520 2db6fc8e80c6c15e6e2b8bbfaadf8039 985 SMART SM00926 257 311 1.7E-18 T 28-03-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CO689_RS03520 2db6fc8e80c6c15e6e2b8bbfaadf8039 985 Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain 5 77 5.6E-9 T 28-03-2018 CO689_RS03520 2db6fc8e80c6c15e6e2b8bbfaadf8039 985 Gene3D G3DSA:2.40.40.20 783 968 8.7E-25 T 28-03-2018 CO689_RS03520 2db6fc8e80c6c15e6e2b8bbfaadf8039 985 SUPERFAMILY SSF50692 793 936 2.08E-31 T 28-03-2018 IPR009010 Aspartate decarboxylase-like domain CO689_RS03520 2db6fc8e80c6c15e6e2b8bbfaadf8039 985 PIRSF PIRSF036643 1 969 0.0 T 28-03-2018 CO689_RS03520 2db6fc8e80c6c15e6e2b8bbfaadf8039 985 Gene3D G3DSA:3.10.20.30 1 115 6.3E-11 T 28-03-2018 IPR012675 Beta-grasp domain CO689_RS03520 2db6fc8e80c6c15e6e2b8bbfaadf8039 985 Gene3D G3DSA:1.10.1060.10 116 154 1.9E-4 T 28-03-2018 CO689_RS03520 2db6fc8e80c6c15e6e2b8bbfaadf8039 985 Pfam PF12838 4Fe-4S dicluster domain 146 204 6.5E-7 T 28-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CO689_RS03520 2db6fc8e80c6c15e6e2b8bbfaadf8039 985 ProSitePatterns PS00932 Prokaryotic molybdopterin oxidoreductases signature 3. 859 886 - T 28-03-2018 IPR006655 Molybdopterin oxidoreductase, prokaryotic, conserved site GO:0009055|GO:0016491|GO:0055114 CO689_RS03520 2db6fc8e80c6c15e6e2b8bbfaadf8039 985 TIGRFAM TIGR01591 Fdh-alpha: formate dehydrogenase, alpha subunit 262 934 2.9E-237 T 28-03-2018 IPR006478 Formate dehydrogenase, alpha subunit GO:0008863|GO:0015942|GO:0055114 KEGG: 00630+1.2.1.2|KEGG: 00680+1.2.1.2|MetaCyc: PWY-1881|MetaCyc: PWY-5497|MetaCyc: PWY-6696 CO689_RS03520 2db6fc8e80c6c15e6e2b8bbfaadf8039 985 Gene3D G3DSA:3.40.50.740 505 782 1.4E-75 T 28-03-2018 CO689_RS07735 7d343ecdc95a8d81e6cebb432cbee5cc 1172 Gene3D G3DSA:3.40.50.300 806 973 2.2E-24 T 28-03-2018 CO689_RS07735 7d343ecdc95a8d81e6cebb432cbee5cc 1172 SMART SM00487 617 807 1.1E-34 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CO689_RS07735 7d343ecdc95a8d81e6cebb432cbee5cc 1172 SUPERFAMILY SSF52540 24 367 2.52E-77 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CO689_RS07735 7d343ecdc95a8d81e6cebb432cbee5cc 1172 SUPERFAMILY SSF52540 374 482 1.03E-18 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CO689_RS07735 7d343ecdc95a8d81e6cebb432cbee5cc 1172 SUPERFAMILY SSF141259 488 565 9.02E-26 T 28-03-2018 IPR003711 CarD-like/TRCF domain CO689_RS07735 7d343ecdc95a8d81e6cebb432cbee5cc 1172 TIGRFAM TIGR00580 mfd: transcription-repair coupling factor 156 1095 0.0 T 28-03-2018 IPR004576 Transcription-repair coupling factor GO:0003684|GO:0005524|GO:0006281 CO689_RS07735 7d343ecdc95a8d81e6cebb432cbee5cc 1172 SUPERFAMILY SSF143517 1012 1163 7.98E-33 T 28-03-2018 CO689_RS07735 7d343ecdc95a8d81e6cebb432cbee5cc 1172 SMART SM00490 840 927 2.2E-17 T 28-03-2018 IPR001650 Helicase, C-terminal CO689_RS07735 7d343ecdc95a8d81e6cebb432cbee5cc 1172 Pfam PF00271 Helicase conserved C-terminal domain 820 926 6.9E-15 T 28-03-2018 IPR001650 Helicase, C-terminal CO689_RS07735 7d343ecdc95a8d81e6cebb432cbee5cc 1172 SMART SM00982 1021 1121 2.3E-39 T 28-03-2018 IPR005118 Transcription-repair-coupling factor, C-terminal domain GO:0006281 CO689_RS07735 7d343ecdc95a8d81e6cebb432cbee5cc 1172 SUPERFAMILY SSF52540 541 800 4.63E-63 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CO689_RS07735 7d343ecdc95a8d81e6cebb432cbee5cc 1172 Gene3D G3DSA:3.40.50.300 461 790 7.0E-38 T 28-03-2018 CO689_RS07735 7d343ecdc95a8d81e6cebb432cbee5cc 1172 Pfam PF02559 CarD-like/TRCF domain 497 592 4.5E-32 T 28-03-2018 IPR003711 CarD-like/TRCF domain CO689_RS07735 7d343ecdc95a8d81e6cebb432cbee5cc 1172 Pfam PF00270 DEAD/DEAH box helicase 622 781 1.7E-17 T 28-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CO689_RS07735 7d343ecdc95a8d81e6cebb432cbee5cc 1172 SMART SM01058 496 593 3.8E-49 T 28-03-2018 IPR003711 CarD-like/TRCF domain CO689_RS07735 7d343ecdc95a8d81e6cebb432cbee5cc 1172 Pfam PF03461 TRCF domain 1022 1114 5.5E-28 T 28-03-2018 IPR005118 Transcription-repair-coupling factor, C-terminal domain GO:0006281 CO689_RS07735 7d343ecdc95a8d81e6cebb432cbee5cc 1172 Gene3D G3DSA:3.40.50.300 1 378 1.2E-4 T 28-03-2018 CO689_RS07735 7d343ecdc95a8d81e6cebb432cbee5cc 1172 Hamap MF_00969 Transcription-repair-coupling factor [mfd]. 37 1125 29.481 T 28-03-2018 IPR004576 Transcription-repair coupling factor GO:0003684|GO:0005524|GO:0006281 CO689_RS07735 7d343ecdc95a8d81e6cebb432cbee5cc 1172 SUPERFAMILY SSF52540 799 1005 9.25E-48 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CO689_RS00870 92eec963f6e507695865ea704333167f 379 Gene3D G3DSA:3.40.640.10 11 240 8.8E-46 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CO689_RS00870 92eec963f6e507695865ea704333167f 379 Gene3D G3DSA:3.90.1150.10 241 368 4.1E-26 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CO689_RS00870 92eec963f6e507695865ea704333167f 379 PIRSF PIRSF005572 1 377 4.5E-105 T 28-03-2018 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250 CO689_RS00870 92eec963f6e507695865ea704333167f 379 Pfam PF00266 Aminotransferase class-V 2 361 3.0E-68 T 28-03-2018 IPR000192 Aminotransferase class V domain CO689_RS00870 92eec963f6e507695865ea704333167f 379 SUPERFAMILY SSF53383 1 372 1.75E-91 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CO689_RS13845 5fe5bbc1dca326cd3d9896d5ce67f95c 315 SUPERFAMILY SSF52096 3 312 1.05E-97 T 28-03-2018 IPR029045 ClpP/crotonase-like domain CO689_RS13845 5fe5bbc1dca326cd3d9896d5ce67f95c 315 Pfam PF03255 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit 1 144 2.6E-64 T 28-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CO689_RS13845 5fe5bbc1dca326cd3d9896d5ce67f95c 315 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 130 146 1.9E-45 T 28-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CO689_RS13845 5fe5bbc1dca326cd3d9896d5ce67f95c 315 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 193 202 1.9E-45 T 28-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CO689_RS13845 5fe5bbc1dca326cd3d9896d5ce67f95c 315 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 109 127 1.9E-45 T 28-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CO689_RS13845 5fe5bbc1dca326cd3d9896d5ce67f95c 315 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 165 178 1.9E-45 T 28-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CO689_RS13845 5fe5bbc1dca326cd3d9896d5ce67f95c 315 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 149 162 1.9E-45 T 28-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CO689_RS13845 5fe5bbc1dca326cd3d9896d5ce67f95c 315 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 84 95 1.9E-45 T 28-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CO689_RS13845 5fe5bbc1dca326cd3d9896d5ce67f95c 315 Gene3D G3DSA:3.90.226.10 8 307 1.0E-65 T 28-03-2018 CO689_RS13845 5fe5bbc1dca326cd3d9896d5ce67f95c 315 Hamap MF_00823 Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha [accA]. 1 312 49.325 T 28-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CO689_RS13845 5fe5bbc1dca326cd3d9896d5ce67f95c 315 TIGRFAM TIGR00513 accA: acetyl-CoA carboxylase, carboxyl transferase, alpha subunit 1 313 2.3E-146 T 28-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CO689_RS04475 54b82f5d98930b56aa941951f1ef020b 336 SMART SM00729 51 259 1.4E-37 T 28-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 CO689_RS04475 54b82f5d98930b56aa941951f1ef020b 336 SMART SM00876 227 317 1.6E-34 T 28-03-2018 IPR010722 Biotin and thiamin synthesis-associated domain KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 CO689_RS04475 54b82f5d98930b56aa941951f1ef020b 336 Gene3D G3DSA:3.20.20.70 1 336 3.8E-47 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CO689_RS04475 54b82f5d98930b56aa941951f1ef020b 336 SUPERFAMILY SSF102114 11 317 1.83E-69 T 28-03-2018 CO689_RS04475 54b82f5d98930b56aa941951f1ef020b 336 Pfam PF06968 Biotin and Thiamin Synthesis associated domain 227 316 8.9E-17 T 28-03-2018 IPR010722 Biotin and thiamin synthesis-associated domain KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 CO689_RS04475 54b82f5d98930b56aa941951f1ef020b 336 Pfam PF04055 Radical SAM superfamily 60 215 1.1E-14 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CO689_RS04475 54b82f5d98930b56aa941951f1ef020b 336 PIRSF PIRSF001619 1 324 3.8E-120 T 28-03-2018 IPR024177 Biotin synthase KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 CO689_RS04475 54b82f5d98930b56aa941951f1ef020b 336 TIGRFAM TIGR00433 bioB: biotin synthase 27 316 2.1E-113 T 28-03-2018 IPR002684 Biotin synthase/Biotin biosynthesis bifunctional protein BioAB GO:0004076|GO:0009102 KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 CO689_RS04475 54b82f5d98930b56aa941951f1ef020b 336 Hamap MF_01694 Biotin synthase [bioB]. 11 318 39.377 T 28-03-2018 IPR002684 Biotin synthase/Biotin biosynthesis bifunctional protein BioAB GO:0004076|GO:0009102 KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 CO689_RS08765 734c86ba633b370a7912534a17345228 302 PRINTS PR00069 Aldo-keto reductase signature 143 160 8.0E-8 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CO689_RS08765 734c86ba633b370a7912534a17345228 302 PRINTS PR00069 Aldo-keto reductase signature 112 130 8.0E-8 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CO689_RS08765 734c86ba633b370a7912534a17345228 302 SUPERFAMILY SSF51430 4 293 2.1E-69 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CO689_RS08765 734c86ba633b370a7912534a17345228 302 Pfam PF00248 Aldo/keto reductase family 15 292 9.3E-60 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CO689_RS08765 734c86ba633b370a7912534a17345228 302 Gene3D G3DSA:3.20.20.100 1 297 3.3E-63 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CO689_RS11955 30294cc49e11ee14758f0d7746957252 315 Gene3D G3DSA:3.20.20.190 33 315 3.0E-77 T 28-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 CO689_RS11955 30294cc49e11ee14758f0d7746957252 315 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 61 306 9.2E-48 T 28-03-2018 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 CO689_RS11955 30294cc49e11ee14758f0d7746957252 315 SUPERFAMILY SSF51695 59 312 1.02E-66 T 28-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 CO689_RS13170 de18b8a978b3279478ff5660f3d82594 135 Gene3D G3DSA:1.10.10.10 6 91 3.1E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS13170 de18b8a978b3279478ff5660f3d82594 135 Pfam PF01475 Ferric uptake regulator family 13 128 1.8E-30 T 28-03-2018 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 CO689_RS13170 de18b8a978b3279478ff5660f3d82594 135 SUPERFAMILY SSF46785 5 132 2.31E-31 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS11855 7d11181b3455610f3b1c2e8b5ba88a18 381 SMART SM00852 4 171 4.4E-34 T 28-03-2018 IPR001453 MoaB/Mog domain CO689_RS11855 7d11181b3455610f3b1c2e8b5ba88a18 381 SUPERFAMILY SSF53218 1 203 7.07E-37 T 28-03-2018 IPR001453 MoaB/Mog domain CO689_RS11855 7d11181b3455610f3b1c2e8b5ba88a18 381 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 1 165 9.2E-27 T 28-03-2018 IPR001453 MoaB/Mog domain CO689_RS11855 7d11181b3455610f3b1c2e8b5ba88a18 381 PIRSF PIRSF006728 1 381 4.5E-107 T 28-03-2018 IPR008135 Competence-induced protein CinA CO689_RS11855 7d11181b3455610f3b1c2e8b5ba88a18 381 Gene3D G3DSA:3.40.980.10 1 171 6.9E-43 T 28-03-2018 IPR001453 MoaB/Mog domain CO689_RS11855 7d11181b3455610f3b1c2e8b5ba88a18 381 TIGRFAM TIGR00200 cinA_nterm: competence/damage-inducible protein CinA N-terminal domain 1 258 3.2E-86 T 28-03-2018 IPR008135 Competence-induced protein CinA CO689_RS11855 7d11181b3455610f3b1c2e8b5ba88a18 381 Hamap MF_00226_B Putative competence-damage inducible protein [cinA]. 1 381 102.698 T 28-03-2018 IPR008135 Competence-induced protein CinA CO689_RS11855 7d11181b3455610f3b1c2e8b5ba88a18 381 Pfam PF00994 Probable molybdopterin binding domain 5 169 5.2E-34 T 28-03-2018 IPR001453 MoaB/Mog domain CO689_RS12955 db5df1df1102b8b91c321cc67b25d649 434 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 25 54 - T 28-03-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 CO689_RS12955 db5df1df1102b8b91c321cc67b25d649 434 SUPERFAMILY SSF51230 2 90 1.27E-27 T 28-03-2018 IPR011053 Single hybrid motif CO689_RS12955 db5df1df1102b8b91c321cc67b25d649 434 Gene3D G3DSA:4.10.320.10 119 188 4.7E-14 T 28-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CO689_RS12955 db5df1df1102b8b91c321cc67b25d649 434 Pfam PF02817 e3 binding domain 130 163 2.2E-11 T 28-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CO689_RS12955 db5df1df1102b8b91c321cc67b25d649 434 SUPERFAMILY SSF47005 127 166 9.16E-11 T 28-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CO689_RS12955 db5df1df1102b8b91c321cc67b25d649 434 Gene3D G3DSA:3.90.1170.30 62 100 4.3E-4 T 28-03-2018 CO689_RS12955 db5df1df1102b8b91c321cc67b25d649 434 Pfam PF00364 Biotin-requiring enzyme 2 74 2.0E-24 T 28-03-2018 IPR000089 Biotin/lipoyl attachment CO689_RS12955 db5df1df1102b8b91c321cc67b25d649 434 SUPERFAMILY SSF52777 205 427 5.34E-82 T 28-03-2018 CO689_RS12955 db5df1df1102b8b91c321cc67b25d649 434 Gene3D G3DSA:2.40.50.100 1 61 2.8E-17 T 28-03-2018 CO689_RS12955 db5df1df1102b8b91c321cc67b25d649 434 Gene3D G3DSA:3.30.559.10 189 432 1.2E-84 T 28-03-2018 CO689_RS12955 db5df1df1102b8b91c321cc67b25d649 434 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 205 426 1.6E-80 T 28-03-2018 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CO689_RS13520 ebaab438d5756ffc46b43682edbb5d7c 757 Pfam PF10141 Single-strand DNA-specific exonuclease, C terminal domain 563 751 5.5E-48 T 28-03-2018 IPR018779 Single-stranded-DNA-specific exonuclease RecJ, C-terminal CO689_RS13520 ebaab438d5756ffc46b43682edbb5d7c 757 Gene3D G3DSA:3.90.1640.10 60 242 2.8E-26 T 28-03-2018 CO689_RS13520 ebaab438d5756ffc46b43682edbb5d7c 757 TIGRFAM TIGR00644 recJ: single-stranded-DNA-specific exonuclease RecJ 28 557 1.9E-180 T 28-03-2018 IPR004610 Bacterial RecJ exonuclease GO:0006281|GO:0006310|GO:0008409 CO689_RS13520 ebaab438d5756ffc46b43682edbb5d7c 757 SUPERFAMILY SSF64182 57 448 6.67E-119 T 28-03-2018 CO689_RS13520 ebaab438d5756ffc46b43682edbb5d7c 757 Pfam PF01368 DHH family 82 224 2.4E-11 T 28-03-2018 IPR001667 DDH domain KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 CO689_RS13520 ebaab438d5756ffc46b43682edbb5d7c 757 Pfam PF02272 DHHA1 domain 312 436 1.7E-22 T 28-03-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 CO689_RS13820 0c76e446637cbbe977984b21958b14a3 421 SUPERFAMILY SSF53659 6 421 3.07E-143 T 28-03-2018 CO689_RS13820 0c76e446637cbbe977984b21958b14a3 421 SMART SM01329 20 417 2.7E-189 T 28-03-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 CO689_RS13820 0c76e446637cbbe977984b21958b14a3 421 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 306 325 - T 28-03-2018 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 CO689_RS13820 0c76e446637cbbe977984b21958b14a3 421 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 21 416 2.0E-122 T 28-03-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 CO689_RS13820 0c76e446637cbbe977984b21958b14a3 421 TIGRFAM TIGR00183 prok_nadp_idh: isocitrate dehydrogenase, NADP-dependent 4 421 7.6E-215 T 28-03-2018 IPR004439 Isocitrate dehydrogenase NADP-dependent, dimeric, prokaryotic GO:0004450|GO:0006099|GO:0055114 KEGG: 00020+1.1.1.42|KEGG: 00480+1.1.1.42|KEGG: 00720+1.1.1.42|MetaCyc: PWY-5913|MetaCyc: PWY-6549|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7124|MetaCyc: PWY-7254|MetaCyc: PWY-7268 CO689_RS13820 0c76e446637cbbe977984b21958b14a3 421 Gene3D G3DSA:3.40.718.10 4 421 3.8E-138 T 28-03-2018 CO689_RS10450 5c828f866ecb28bdfb3c607933cb0f79 256 SMART SM00382 25 213 1.9E-17 T 28-03-2018 IPR003593 AAA+ ATPase domain CO689_RS10450 5c828f866ecb28bdfb3c607933cb0f79 256 Gene3D G3DSA:3.40.50.300 1 244 3.1E-60 T 28-03-2018 CO689_RS10450 5c828f866ecb28bdfb3c607933cb0f79 256 Pfam PF00005 ABC transporter 17 163 2.5E-32 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CO689_RS10450 5c828f866ecb28bdfb3c607933cb0f79 256 SUPERFAMILY SSF52540 2 225 3.48E-60 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CO689_RS10450 5c828f866ecb28bdfb3c607933cb0f79 256 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CO689_RS09440 23c15ee2f6eec97dbbe7ee550d2ebd32 180 Pfam PF00881 Nitroreductase family 7 157 1.4E-20 T 28-03-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 CO689_RS09440 23c15ee2f6eec97dbbe7ee550d2ebd32 180 SUPERFAMILY SSF55469 2 177 3.01E-29 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CO689_RS09440 23c15ee2f6eec97dbbe7ee550d2ebd32 180 Gene3D G3DSA:3.40.109.10 1 180 2.2E-26 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CO689_RS09890 8daab9970bbfa67b93cec4c2203257ec 259 TIGRFAM TIGR01460 HAD-SF-IIA: HAD hydrolase, family IIA 8 229 2.1E-41 T 28-03-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA CO689_RS09890 8daab9970bbfa67b93cec4c2203257ec 259 Gene3D G3DSA:3.40.50.1000 1 257 6.8E-33 T 28-03-2018 IPR023214 HAD-like domain CO689_RS09890 8daab9970bbfa67b93cec4c2203257ec 259 Pfam PF13344 Haloacid dehalogenase-like hydrolase 8 106 6.8E-27 T 28-03-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA CO689_RS09890 8daab9970bbfa67b93cec4c2203257ec 259 PIRSF PIRSF000915 1 259 3.6E-57 T 28-03-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA CO689_RS09890 8daab9970bbfa67b93cec4c2203257ec 259 TIGRFAM TIGR01457 HAD-SF-IIA-hyp2: HAD hydrolase, TIGR01457 family 4 252 9.8E-101 T 28-03-2018 IPR006354 HAD-superfamily hydrolase, subfamily IIA, hypothetical 1 CO689_RS09890 8daab9970bbfa67b93cec4c2203257ec 259 Pfam PF13242 HAD-hyrolase-like 180 252 5.5E-21 T 28-03-2018 CO689_RS09890 8daab9970bbfa67b93cec4c2203257ec 259 SUPERFAMILY SSF56784 3 253 9.76E-67 T 28-03-2018 IPR023214 HAD-like domain CO689_RS07980 2ed19aa61c66bec96731cfd6f627b913 466 Pfam PF09190 DALR domain 351 412 8.4E-15 T 28-03-2018 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 CO689_RS07980 2ed19aa61c66bec96731cfd6f627b913 466 Pfam PF01406 tRNA synthetases class I (C) catalytic domain 15 312 2.2E-134 T 28-03-2018 IPR032678 tRNA synthetases class I, catalytic domain KEGG: 00970+6.1.1.16 CO689_RS07980 2ed19aa61c66bec96731cfd6f627b913 466 SMART SM00840 351 417 8.8E-14 T 28-03-2018 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 CO689_RS07980 2ed19aa61c66bec96731cfd6f627b913 466 SUPERFAMILY SSF47323 338 465 1.79E-32 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CO689_RS07980 2ed19aa61c66bec96731cfd6f627b913 466 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 221 242 6.1E-29 T 28-03-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 CO689_RS07980 2ed19aa61c66bec96731cfd6f627b913 466 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 25 36 6.1E-29 T 28-03-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 CO689_RS07980 2ed19aa61c66bec96731cfd6f627b913 466 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 190 208 6.1E-29 T 28-03-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 CO689_RS07980 2ed19aa61c66bec96731cfd6f627b913 466 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 61 70 6.1E-29 T 28-03-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 CO689_RS07980 2ed19aa61c66bec96731cfd6f627b913 466 TIGRFAM TIGR00435 cysS: cysteine--tRNA ligase 2 465 7.5E-182 T 28-03-2018 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 CO689_RS07980 2ed19aa61c66bec96731cfd6f627b913 466 Hamap MF_00041 Cysteine--tRNA ligase [cysS]. 2 466 38.493 T 28-03-2018 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 CO689_RS07980 2ed19aa61c66bec96731cfd6f627b913 466 Gene3D G3DSA:1.20.120.640 305 408 5.7E-17 T 28-03-2018 CO689_RS07980 2ed19aa61c66bec96731cfd6f627b913 466 Gene3D G3DSA:3.40.50.620 1 304 5.3E-92 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CO689_RS07980 2ed19aa61c66bec96731cfd6f627b913 466 SUPERFAMILY SSF52374 2 311 8.85E-102 T 28-03-2018 CO689_RS03065 89dc65759d058cb9d1455d4e05bb2ea0 166 SUPERFAMILY SSF54211 79 159 1.21E-26 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CO689_RS03065 89dc65759d058cb9d1455d4e05bb2ea0 166 Gene3D G3DSA:3.30.160.20 10 72 5.3E-29 T 28-03-2018 CO689_RS03065 89dc65759d058cb9d1455d4e05bb2ea0 166 SUPERFAMILY SSF54768 7 76 1.78E-24 T 28-03-2018 CO689_RS03065 89dc65759d058cb9d1455d4e05bb2ea0 166 ProSitePatterns PS00585 Ribosomal protein S5 signature. 28 60 - T 28-03-2018 IPR018192 Ribosomal protein S5, N-terminal, conserved site CO689_RS03065 89dc65759d058cb9d1455d4e05bb2ea0 166 Hamap MF_01307_B 30S ribosomal protein S5 [rpsE]. 1 163 36.827 T 28-03-2018 IPR005712 Ribosomal protein S5, bacterial-type GO:0003735|GO:0006412|GO:0015935 CO689_RS03065 89dc65759d058cb9d1455d4e05bb2ea0 166 Pfam PF03719 Ribosomal protein S5, C-terminal domain 86 157 3.1E-33 T 28-03-2018 IPR005324 Ribosomal protein S5, C-terminal GO:0003735|GO:0005840|GO:0006412 CO689_RS03065 89dc65759d058cb9d1455d4e05bb2ea0 166 TIGRFAM TIGR01021 rpsE_bact: ribosomal protein uS5 9 163 1.1E-70 T 28-03-2018 IPR005712 Ribosomal protein S5, bacterial-type GO:0003735|GO:0006412|GO:0015935 CO689_RS03065 89dc65759d058cb9d1455d4e05bb2ea0 166 Pfam PF00333 Ribosomal protein S5, N-terminal domain 11 75 4.1E-30 T 28-03-2018 IPR013810 Ribosomal protein S5, N-terminal GO:0003723|GO:0003735|GO:0005840|GO:0006412 CO689_RS03065 89dc65759d058cb9d1455d4e05bb2ea0 166 Gene3D G3DSA:3.30.230.10 76 166 1.7E-33 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CO689_RS09795 aa666a63cf7ffa25156065c22ef9488e 1668 Pfam PF10145 Phage-related minor tail protein 207 406 2.5E-59 T 28-03-2018 IPR010090 Phage tail tape measure protein CO689_RS09795 aa666a63cf7ffa25156065c22ef9488e 1668 Gene3D G3DSA:1.20.120.330 24 213 6.4E-7 T 28-03-2018 CO689_RS09795 aa666a63cf7ffa25156065c22ef9488e 1668 Gene3D G3DSA:1.20.120.20 1029 1274 2.2E-9 T 28-03-2018 CO689_RS09795 aa666a63cf7ffa25156065c22ef9488e 1668 TIGRFAM TIGR01760 tape_meas_TP901: phage tail tape measure protein, TP901 family, core region 168 511 7.6E-85 T 28-03-2018 IPR010090 Phage tail tape measure protein CO689_RS09795 aa666a63cf7ffa25156065c22ef9488e 1668 Gene3D G3DSA:1.10.530.10 1418 1664 5.2E-12 T 28-03-2018 CO689_RS09795 aa666a63cf7ffa25156065c22ef9488e 1668 Gene3D G3DSA:1.10.287.700 952 1028 9.1E-11 T 28-03-2018 CO689_RS09795 aa666a63cf7ffa25156065c22ef9488e 1668 Gene3D G3DSA:1.10.287.1060 271 386 0.08 T 28-03-2018 CO689_RS09795 aa666a63cf7ffa25156065c22ef9488e 1668 SUPERFAMILY SSF53955 1434 1528 1.24E-9 T 28-03-2018 IPR023346 Lysozyme-like domain CO689_RS09795 aa666a63cf7ffa25156065c22ef9488e 1668 Gene3D G3DSA:2.70.70.10 1275 1417 2.6E-27 T 28-03-2018 CO689_RS09795 aa666a63cf7ffa25156065c22ef9488e 1668 SUPERFAMILY SSF57997 23 138 5.69E-6 T 28-03-2018 CO689_RS09795 aa666a63cf7ffa25156065c22ef9488e 1668 Pfam PF01464 Transglycosylase SLT domain 1462 1541 1.2E-5 T 28-03-2018 IPR008258 Transglycosylase SLT domain 1 CO689_RS09795 aa666a63cf7ffa25156065c22ef9488e 1668 Gene3D G3DSA:1.20.5.1230 820 951 1.3E-11 T 28-03-2018 CO689_RS09795 aa666a63cf7ffa25156065c22ef9488e 1668 Gene3D G3DSA:1.20.5.1230 647 817 2.1E-10 T 28-03-2018 CO689_RS09795 aa666a63cf7ffa25156065c22ef9488e 1668 Gene3D G3DSA:1.20.5.1230 387 634 1.0E-11 T 28-03-2018 CO689_RS09795 aa666a63cf7ffa25156065c22ef9488e 1668 SUPERFAMILY SSF48371 459 515 1.38E-10 T 28-03-2018 IPR016024 Armadillo-type fold GO:0005488 CO689_RS09795 aa666a63cf7ffa25156065c22ef9488e 1668 SUPERFAMILY SSF48371 828 972 1.38E-10 T 28-03-2018 IPR016024 Armadillo-type fold GO:0005488 CO689_RS09795 aa666a63cf7ffa25156065c22ef9488e 1668 SUPERFAMILY SSF48371 597 757 1.38E-10 T 28-03-2018 IPR016024 Armadillo-type fold GO:0005488 CO689_RS09795 aa666a63cf7ffa25156065c22ef9488e 1668 SUPERFAMILY SSF51261 1316 1421 3.03E-29 T 28-03-2018 IPR011055 Duplicated hybrid motif CO689_RS09795 aa666a63cf7ffa25156065c22ef9488e 1668 Pfam PF01551 Peptidase family M23 1319 1409 1.1E-19 T 28-03-2018 IPR016047 Peptidase M23 CO689_RS06465 c3e71626045af54b13abae96ad8aad3c 277 Pfam PF02517 CAAX protease self-immunity 129 216 4.7E-16 T 28-03-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 CO689_RS04545 4f54c97faf377298bd4a8cdec5c3e27c 749 SUPERFAMILY SSF51998 8 749 2.23E-288 T 28-03-2018 CO689_RS04545 4f54c97faf377298bd4a8cdec5c3e27c 749 PIRSF PIRSF000379 8 749 0.0 T 28-03-2018 IPR005949 Formate acetyltransferase GO:0005737|GO:0005975|GO:0008861 KEGG: 00620+2.3.1.54|KEGG: 00640+2.3.1.54|KEGG: 00650+2.3.1.54|MetaCyc: PWY-5480|MetaCyc: PWY-5485|MetaCyc: PWY-5493 CO689_RS04545 4f54c97faf377298bd4a8cdec5c3e27c 749 ProSitePatterns PS00850 Glycine radical domain signature. 719 727 - T 28-03-2018 IPR019777 Formate C-acetyltransferase glycine radical, conserved site CO689_RS04545 4f54c97faf377298bd4a8cdec5c3e27c 749 Gene3D G3DSA:3.20.70.20 2 749 2.0E-299 T 28-03-2018 CO689_RS04545 4f54c97faf377298bd4a8cdec5c3e27c 749 Pfam PF01228 Glycine radical 624 730 1.2E-42 T 28-03-2018 IPR001150 Glycine radical domain GO:0003824|GO:0008152 CO689_RS04545 4f54c97faf377298bd4a8cdec5c3e27c 749 TIGRFAM TIGR01255 pyr_form_ly_1: formate acetyltransferase 11 749 0.0 T 28-03-2018 IPR005949 Formate acetyltransferase GO:0005737|GO:0005975|GO:0008861 KEGG: 00620+2.3.1.54|KEGG: 00640+2.3.1.54|KEGG: 00650+2.3.1.54|MetaCyc: PWY-5480|MetaCyc: PWY-5485|MetaCyc: PWY-5493 CO689_RS04545 4f54c97faf377298bd4a8cdec5c3e27c 749 Pfam PF02901 Pyruvate formate lyase-like 26 608 6.5E-210 T 28-03-2018 IPR004184 Pyruvate formate lyase domain GO:0003824 CO689_RS01015 2c2bb3a569a3f22b3dde01b80cee0878 358 SUPERFAMILY SSF101821 75 182 3.66E-26 T 28-03-2018 CO689_RS01015 2c2bb3a569a3f22b3dde01b80cee0878 358 Pfam PF05343 M42 glutamyl aminopeptidase 49 338 1.1E-97 T 28-03-2018 IPR008007 Peptidase M42 CO689_RS01015 2c2bb3a569a3f22b3dde01b80cee0878 358 Gene3D G3DSA:3.40.630.10 161 219 8.5E-9 T 28-03-2018 CO689_RS01015 2c2bb3a569a3f22b3dde01b80cee0878 358 Gene3D G3DSA:3.40.630.10 220 345 1.4E-28 T 28-03-2018 CO689_RS01015 2c2bb3a569a3f22b3dde01b80cee0878 358 PIRSF PIRSF001123 5 358 3.7E-131 T 28-03-2018 IPR008007 Peptidase M42 CO689_RS01015 2c2bb3a569a3f22b3dde01b80cee0878 358 Gene3D G3DSA:2.40.30.40 74 160 1.4E-24 T 28-03-2018 IPR023367 Peptidase M42, domain 2 CO689_RS01015 2c2bb3a569a3f22b3dde01b80cee0878 358 SUPERFAMILY SSF53187 174 352 2.08E-66 T 28-03-2018 CO689_RS01015 2c2bb3a569a3f22b3dde01b80cee0878 358 SUPERFAMILY SSF53187 7 85 2.08E-66 T 28-03-2018 CO689_RS02375 e935b49c85189c4bef38464c236e2276 289 PRINTS PR00701 60kDa inner membrane protein signature 214 237 3.0E-5 T 28-03-2018 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 CO689_RS02375 e935b49c85189c4bef38464c236e2276 289 PRINTS PR00701 60kDa inner membrane protein signature 128 151 3.0E-5 T 28-03-2018 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 CO689_RS02375 e935b49c85189c4bef38464c236e2276 289 Pfam PF02096 60Kd inner membrane protein 55 247 1.2E-43 T 28-03-2018 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 CO689_RS02375 e935b49c85189c4bef38464c236e2276 289 TIGRFAM TIGR03592 yidC_oxa1_cterm: membrane protein insertase, YidC/Oxa1 family 55 247 1.1E-46 T 28-03-2018 IPR028055 Membrane insertase YidC/Oxa1, C-terminal CO689_RS02375 e935b49c85189c4bef38464c236e2276 289 Hamap MF_01811 Membrane protein insertase YidC [yidC]. 1 251 27.797 T 28-03-2018 IPR023060 Membrane insertase YidC/YidC1/YidC2, Firmicutes CO689_RS09905 00375295307a6fe13b8a7a9c09a20fe7 484 SUPERFAMILY SSF56801 4 482 4.45E-115 T 28-03-2018 CO689_RS09905 00375295307a6fe13b8a7a9c09a20fe7 484 Gene3D G3DSA:3.40.50.980 146 298 9.7E-34 T 28-03-2018 CO689_RS09905 00375295307a6fe13b8a7a9c09a20fe7 484 Gene3D G3DSA:2.30.38.10 299 379 2.1E-11 T 28-03-2018 CO689_RS09905 00375295307a6fe13b8a7a9c09a20fe7 484 Pfam PF13193 AMP-binding enzyme C-terminal domain 394 472 2.8E-12 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CO689_RS09905 00375295307a6fe13b8a7a9c09a20fe7 484 Hamap MF_00593 D-alanine--poly(phosphoribitol) ligase subunit 1 [dltA]. 1 484 211.126 T 28-03-2018 IPR010072 D-alanine--poly(phosphoribitol) ligase subunit 1 GO:0005524|GO:0047473|GO:0070395 KEGG: 00473+6.1.1.13 CO689_RS09905 00375295307a6fe13b8a7a9c09a20fe7 484 Gene3D G3DSA:3.30.300.30 380 484 4.0E-29 T 28-03-2018 CO689_RS09905 00375295307a6fe13b8a7a9c09a20fe7 484 Gene3D G3DSA:3.40.50.980 2 145 1.4E-29 T 28-03-2018 CO689_RS09905 00375295307a6fe13b8a7a9c09a20fe7 484 TIGRFAM TIGR01734 D-ala-DACP-lig: D-alanine--poly(phosphoribitol) ligase, subunit 1 3 483 4.7E-201 T 28-03-2018 IPR010072 D-alanine--poly(phosphoribitol) ligase subunit 1 GO:0005524|GO:0047473|GO:0070395 KEGG: 00473+6.1.1.13 CO689_RS09905 00375295307a6fe13b8a7a9c09a20fe7 484 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 29 410 2.0E-98 T 28-03-2018 IPR010071 Amino acid adenylation domain CO689_RS09905 00375295307a6fe13b8a7a9c09a20fe7 484 Pfam PF00501 AMP-binding enzyme 9 385 1.4E-72 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CO689_RS13375 b48ea0cbfdbce85474a1e18514f68726 269 Pfam PF08501 Shikimate dehydrogenase substrate binding domain 5 87 3.2E-28 T 28-03-2018 IPR013708 Shikimate dehydrogenase substrate binding, N-terminal GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 CO689_RS13375 b48ea0cbfdbce85474a1e18514f68726 269 SUPERFAMILY SSF53223 2 99 5.3E-32 T 28-03-2018 CO689_RS13375 b48ea0cbfdbce85474a1e18514f68726 269 SUPERFAMILY SSF51735 100 264 6.48E-37 T 28-03-2018 IPR016040 NAD(P)-binding domain CO689_RS13375 b48ea0cbfdbce85474a1e18514f68726 269 Gene3D G3DSA:3.40.50.720 111 268 2.5E-28 T 28-03-2018 CO689_RS13375 b48ea0cbfdbce85474a1e18514f68726 269 Pfam PF01488 Shikimate / quinate 5-dehydrogenase 110 185 2.4E-9 T 28-03-2018 IPR006151 Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase CO689_RS13375 b48ea0cbfdbce85474a1e18514f68726 269 Gene3D G3DSA:3.40.50.10860 1 110 1.6E-39 T 28-03-2018 CO689_RS13375 b48ea0cbfdbce85474a1e18514f68726 269 TIGRFAM TIGR00507 aroE: shikimate dehydrogenase 3 265 5.1E-80 T 28-03-2018 IPR011342 Shikimate dehydrogenase GO:0004764|GO:0019632|GO:0050661|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 CO689_RS13375 b48ea0cbfdbce85474a1e18514f68726 269 Hamap MF_00222 Shikimate dehydrogenase (NADP(+)) [aroE]. 1 263 31.426 T 28-03-2018 IPR022893 Shikimate dehydrogenase family GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 CO689_RS01395 785f94029cd75ace8af3a38e817ef2f3 424 PRINTS PR00173 Glutamate-aspartate symporter signature 4 24 4.3E-50 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CO689_RS01395 785f94029cd75ace8af3a38e817ef2f3 424 PRINTS PR00173 Glutamate-aspartate symporter signature 370 390 4.3E-50 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CO689_RS01395 785f94029cd75ace8af3a38e817ef2f3 424 PRINTS PR00173 Glutamate-aspartate symporter signature 51 71 4.3E-50 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CO689_RS01395 785f94029cd75ace8af3a38e817ef2f3 424 PRINTS PR00173 Glutamate-aspartate symporter signature 207 226 4.3E-50 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CO689_RS01395 785f94029cd75ace8af3a38e817ef2f3 424 PRINTS PR00173 Glutamate-aspartate symporter signature 308 334 4.3E-50 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CO689_RS01395 785f94029cd75ace8af3a38e817ef2f3 424 PRINTS PR00173 Glutamate-aspartate symporter signature 81 106 4.3E-50 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CO689_RS01395 785f94029cd75ace8af3a38e817ef2f3 424 PRINTS PR00173 Glutamate-aspartate symporter signature 159 181 4.3E-50 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CO689_RS01395 785f94029cd75ace8af3a38e817ef2f3 424 PRINTS PR00173 Glutamate-aspartate symporter signature 343 362 4.3E-50 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CO689_RS01395 785f94029cd75ace8af3a38e817ef2f3 424 Gene3D G3DSA:1.10.3860.10 1 421 1.9E-127 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CO689_RS01395 785f94029cd75ace8af3a38e817ef2f3 424 SUPERFAMILY SSF118215 6 416 3.01E-110 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CO689_RS01395 785f94029cd75ace8af3a38e817ef2f3 424 Pfam PF00375 Sodium:dicarboxylate symporter family 6 415 4.1E-124 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CO689_RS05980 ab42e0881864011e43234edf20e35daa 444 Pfam PF05598 Transposase domain (DUF772) 52 127 3.1E-21 T 28-03-2018 IPR008490 Transposase InsH, N-terminal CO689_RS05980 ab42e0881864011e43234edf20e35daa 444 Pfam PF13751 Transposase DDE domain 321 439 1.9E-22 T 28-03-2018 IPR025668 Transposase DDE domain CO689_RS07725 e0e59fa122d3c9b2ab4a717f83592150 215 Hamap MF_01334 50S ribosomal protein L25 [rplY]. 2 182 25.741 T 28-03-2018 IPR001021 Ribosomal protein L25, long-form GO:0003735|GO:0005840|GO:0006412|GO:0008097 CO689_RS07725 e0e59fa122d3c9b2ab4a717f83592150 215 Gene3D G3DSA:2.170.120.20 98 186 3.5E-27 T 28-03-2018 IPR020057 Ribosomal protein L25, beta domain CO689_RS07725 e0e59fa122d3c9b2ab4a717f83592150 215 SUPERFAMILY SSF50715 3 188 6.63E-53 T 28-03-2018 IPR011035 Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding domain GO:0006412 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 CO689_RS07725 e0e59fa122d3c9b2ab4a717f83592150 215 TIGRFAM TIGR00731 bL25_bact_ctc: ribosomal protein bL25, Ctc-form 13 179 1.1E-48 T 28-03-2018 IPR001021 Ribosomal protein L25, long-form GO:0003735|GO:0005840|GO:0006412|GO:0008097 CO689_RS07725 e0e59fa122d3c9b2ab4a717f83592150 215 Pfam PF01386 Ribosomal L25p family 12 91 5.9E-20 T 28-03-2018 IPR029751 Ribosomal protein L25 GO:0003735|GO:0005840|GO:0006412|GO:0008097 CO689_RS07725 e0e59fa122d3c9b2ab4a717f83592150 215 Gene3D G3DSA:2.40.240.10 11 94 6.1E-24 T 28-03-2018 IPR020056 Ribosomal protein L25/Gln-tRNA synthetase, beta-barrel domain Reactome: R-HSA-2408517|Reactome: R-HSA-379716 CO689_RS07725 e0e59fa122d3c9b2ab4a717f83592150 215 ProDom PD012503 RIBOSOMAL L25 50S RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN STRESS GENERAL CTC RRNA 13 94 1.0E-35 T 28-03-2018 IPR029751 Ribosomal protein L25 GO:0003735|GO:0005840|GO:0006412|GO:0008097 CO689_RS07725 e0e59fa122d3c9b2ab4a717f83592150 215 Pfam PF14693 Ribosomal protein TL5, C-terminal domain 101 181 8.9E-26 T 28-03-2018 IPR020057 Ribosomal protein L25, beta domain CO689_RS13475 e7eddb37e8327ecd673fc7560640587d 426 Pfam PF12002 MgsA AAA+ ATPase C terminal 254 419 1.8E-64 T 28-03-2018 IPR021886 MgsA AAA+ ATPase C-terminal CO689_RS13475 e7eddb37e8327ecd673fc7560640587d 426 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 43 145 6.5E-18 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CO689_RS13475 e7eddb37e8327ecd673fc7560640587d 426 Gene3D G3DSA:1.10.8.60 140 229 3.7E-18 T 28-03-2018 CO689_RS13475 e7eddb37e8327ecd673fc7560640587d 426 SMART SM00382 39 151 8.6E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain CO689_RS13475 e7eddb37e8327ecd673fc7560640587d 426 SUPERFAMILY SSF48019 239 422 2.78E-70 T 28-03-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 CO689_RS13475 e7eddb37e8327ecd673fc7560640587d 426 Gene3D G3DSA:3.40.50.300 2 139 5.4E-28 T 28-03-2018 CO689_RS13475 e7eddb37e8327ecd673fc7560640587d 426 Gene3D G3DSA:1.20.272.10 238 331 3.4E-36 T 28-03-2018 CO689_RS13475 e7eddb37e8327ecd673fc7560640587d 426 Pfam PF16193 AAA C-terminal domain 175 253 3.0E-23 T 28-03-2018 IPR032423 AAA C-terminal domain CO689_RS13475 e7eddb37e8327ecd673fc7560640587d 426 SUPERFAMILY SSF52540 4 220 1.0E-39 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CO689_RS13475 e7eddb37e8327ecd673fc7560640587d 426 Gene3D G3DSA:1.10.3710.10 334 426 2.4E-29 T 28-03-2018 CO689_RS10510 5728fd12b89011f77daf55ac900226f6 187 Pfam PF00583 Acetyltransferase (GNAT) family 60 164 3.7E-13 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CO689_RS10510 5728fd12b89011f77daf55ac900226f6 187 SUPERFAMILY SSF55729 2 182 9.61E-28 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CO689_RS10510 5728fd12b89011f77daf55ac900226f6 187 Gene3D G3DSA:3.40.630.30 1 183 7.1E-31 T 28-03-2018 CO689_RS06750 eaa098bacccd7c11b21512ed5760f8b2 334 SMART SM00829 17 329 3.1E-5 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CO689_RS06750 eaa098bacccd7c11b21512ed5760f8b2 334 Pfam PF16884 N-terminal domain of oxidoreductase 5 110 4.2E-34 T 28-03-2018 CO689_RS06750 eaa098bacccd7c11b21512ed5760f8b2 334 Pfam PF00107 Zinc-binding dehydrogenase 156 290 6.1E-21 T 28-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CO689_RS06750 eaa098bacccd7c11b21512ed5760f8b2 334 SUPERFAMILY SSF51735 122 296 9.41E-48 T 28-03-2018 IPR016040 NAD(P)-binding domain CO689_RS06750 eaa098bacccd7c11b21512ed5760f8b2 334 SUPERFAMILY SSF50129 2 141 7.07E-36 T 28-03-2018 IPR011032 GroES-like CO689_RS06750 eaa098bacccd7c11b21512ed5760f8b2 334 Gene3D G3DSA:3.90.180.10 1 146 4.8E-35 T 28-03-2018 CO689_RS06750 eaa098bacccd7c11b21512ed5760f8b2 334 Gene3D G3DSA:3.40.50.720 147 273 1.8E-25 T 28-03-2018 CO689_RS10710 d2113253ad012c37da39084edbf35117 286 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 33 55 1.2E-78 T 28-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CO689_RS10710 d2113253ad012c37da39084edbf35117 286 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 154 174 1.2E-78 T 28-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CO689_RS10710 d2113253ad012c37da39084edbf35117 286 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 238 254 1.2E-78 T 28-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CO689_RS10710 d2113253ad012c37da39084edbf35117 286 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 109 130 1.2E-78 T 28-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CO689_RS10710 d2113253ad012c37da39084edbf35117 286 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 74 101 1.2E-78 T 28-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CO689_RS10710 d2113253ad012c37da39084edbf35117 286 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 255 273 1.2E-78 T 28-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CO689_RS10710 d2113253ad012c37da39084edbf35117 286 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 203 232 1.2E-78 T 28-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CO689_RS10710 d2113253ad012c37da39084edbf35117 286 ProSitePatterns PS00767 Tetrahydrofolate dehydrogenase/cyclohydrolase signature 2. 259 267 - T 28-03-2018 IPR020867 Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site GO:0003824|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CO689_RS10710 d2113253ad012c37da39084edbf35117 286 Pfam PF02882 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 123 280 1.1E-67 T 28-03-2018 IPR020631 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain GO:0004488 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CO689_RS10710 d2113253ad012c37da39084edbf35117 286 Hamap MF_01576 Bifunctional protein FolD [folD]. 3 282 38.097 T 28-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CO689_RS10710 d2113253ad012c37da39084edbf35117 286 SUPERFAMILY SSF51735 122 278 1.37E-48 T 28-03-2018 IPR016040 NAD(P)-binding domain CO689_RS10710 d2113253ad012c37da39084edbf35117 286 Pfam PF00763 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain 5 120 1.4E-39 T 28-03-2018 IPR020630 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CO689_RS10710 d2113253ad012c37da39084edbf35117 286 Gene3D G3DSA:3.40.50.10860 11 139 2.1E-47 T 28-03-2018 CO689_RS10710 d2113253ad012c37da39084edbf35117 286 SUPERFAMILY SSF53223 1 121 2.01E-39 T 28-03-2018 CO689_RS10710 d2113253ad012c37da39084edbf35117 286 Gene3D G3DSA:3.40.50.720 140 263 6.8E-41 T 28-03-2018 CO689_RS10685 a5753fa149a67910a9f20055cd93d311 660 PRINTS PR01165 Cytochrome c oxidase subunit I signature 319 334 6.3E-98 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CO689_RS10685 a5753fa149a67910a9f20055cd93d311 660 PRINTS PR01165 Cytochrome c oxidase subunit I signature 273 294 6.3E-98 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CO689_RS10685 a5753fa149a67910a9f20055cd93d311 660 PRINTS PR01165 Cytochrome c oxidase subunit I signature 193 211 6.3E-98 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CO689_RS10685 a5753fa149a67910a9f20055cd93d311 660 PRINTS PR01165 Cytochrome c oxidase subunit I signature 222 241 6.3E-98 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CO689_RS10685 a5753fa149a67910a9f20055cd93d311 660 PRINTS PR01165 Cytochrome c oxidase subunit I signature 343 364 6.3E-98 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CO689_RS10685 a5753fa149a67910a9f20055cd93d311 660 PRINTS PR01165 Cytochrome c oxidase subunit I signature 456 477 6.3E-98 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CO689_RS10685 a5753fa149a67910a9f20055cd93d311 660 PRINTS PR01165 Cytochrome c oxidase subunit I signature 93 116 6.3E-98 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CO689_RS10685 a5753fa149a67910a9f20055cd93d311 660 PRINTS PR01165 Cytochrome c oxidase subunit I signature 120 144 6.3E-98 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CO689_RS10685 a5753fa149a67910a9f20055cd93d311 660 PRINTS PR01165 Cytochrome c oxidase subunit I signature 46 71 6.3E-98 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CO689_RS10685 a5753fa149a67910a9f20055cd93d311 660 PRINTS PR01165 Cytochrome c oxidase subunit I signature 162 174 6.3E-98 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CO689_RS10685 a5753fa149a67910a9f20055cd93d311 660 PRINTS PR01165 Cytochrome c oxidase subunit I signature 378 396 6.3E-98 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CO689_RS10685 a5753fa149a67910a9f20055cd93d311 660 PRINTS PR01165 Cytochrome c oxidase subunit I signature 406 425 6.3E-98 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CO689_RS10685 a5753fa149a67910a9f20055cd93d311 660 Gene3D G3DSA:1.20.210.10 42 555 1.2E-179 T 28-03-2018 IPR023616 Cytochrome c oxidase-like, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CO689_RS10685 a5753fa149a67910a9f20055cd93d311 660 Gene3D G3DSA:1.10.287.70 569 636 9.6E-13 T 28-03-2018 CO689_RS10685 a5753fa149a67910a9f20055cd93d311 660 SUPERFAMILY SSF81442 44 553 1.96E-168 T 28-03-2018 IPR023616 Cytochrome c oxidase-like, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CO689_RS10685 a5753fa149a67910a9f20055cd93d311 660 ProSitePatterns PS00077 Heme-copper oxidase catalytic subunit, copper B binding region signature. 275 329 - T 28-03-2018 IPR023615 Cytochrome c oxidase, subunit I, copper-binding site GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CO689_RS10685 a5753fa149a67910a9f20055cd93d311 660 TIGRFAM TIGR02882 QoxB: cytochrome aa3 quinol oxidase, subunit I 5 645 0.0 T 28-03-2018 IPR014233 Quinol oxidase subunit I GO:0005507|GO:0016021|GO:0016682|GO:0020037|GO:0055114 CO689_RS10685 a5753fa149a67910a9f20055cd93d311 660 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 55 500 5.5E-139 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CO689_RS12480 1858b1132f4350edb6a2d28feb1821df 422 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 376 389 4.0E-19 T 28-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 CO689_RS12480 1858b1132f4350edb6a2d28feb1821df 422 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 190 203 4.0E-19 T 28-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 CO689_RS12480 1858b1132f4350edb6a2d28feb1821df 422 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 275 294 4.0E-19 T 28-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 CO689_RS12480 1858b1132f4350edb6a2d28feb1821df 422 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 78 90 4.0E-19 T 28-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 CO689_RS12480 1858b1132f4350edb6a2d28feb1821df 422 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 58 76 4.0E-19 T 28-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 CO689_RS12480 1858b1132f4350edb6a2d28feb1821df 422 Gene3D G3DSA:2.40.37.10 271 421 4.8E-41 T 28-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 CO689_RS12480 1858b1132f4350edb6a2d28feb1821df 422 Pfam PF00278 Pyridoxal-dependent decarboxylase, C-terminal sheet domain 122 376 5.8E-18 T 28-03-2018 IPR022643 Orn/DAP/Arg decarboxylase 2, C-terminal GO:0003824 CO689_RS12480 1858b1132f4350edb6a2d28feb1821df 422 ProSitePatterns PS00878 Orn/DAP/Arg decarboxylases family 2 pyridoxal-P attachment site. 58 76 - T 28-03-2018 IPR022653 Orn/DAP/Arg decarboxylase 2, pyridoxal-phosphate binding site CO689_RS12480 1858b1132f4350edb6a2d28feb1821df 422 SUPERFAMILY SSF50621 264 418 2.3E-47 T 28-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 CO689_RS12480 1858b1132f4350edb6a2d28feb1821df 422 PRINTS PR01181 Diaminopimelate decarboxylase signature 304 322 1.1E-25 T 28-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CO689_RS12480 1858b1132f4350edb6a2d28feb1821df 422 PRINTS PR01181 Diaminopimelate decarboxylase signature 386 408 1.1E-25 T 28-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CO689_RS12480 1858b1132f4350edb6a2d28feb1821df 422 PRINTS PR01181 Diaminopimelate decarboxylase signature 162 171 1.1E-25 T 28-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CO689_RS12480 1858b1132f4350edb6a2d28feb1821df 422 PRINTS PR01181 Diaminopimelate decarboxylase signature 76 93 1.1E-25 T 28-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CO689_RS12480 1858b1132f4350edb6a2d28feb1821df 422 Hamap MF_02120 Diaminopimelate decarboxylase [lysA]. 14 419 40.397 T 28-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CO689_RS12480 1858b1132f4350edb6a2d28feb1821df 422 Pfam PF02784 Pyridoxal-dependent decarboxylase, pyridoxal binding domain 34 285 9.2E-66 T 28-03-2018 IPR022644 Orn/DAP/Arg decarboxylase 2, N-terminal GO:0003824 CO689_RS12480 1858b1132f4350edb6a2d28feb1821df 422 Gene3D G3DSA:3.20.20.10 33 270 1.4E-64 T 28-03-2018 IPR029066 PLP-binding barrel CO689_RS12480 1858b1132f4350edb6a2d28feb1821df 422 TIGRFAM TIGR01048 lysA: diaminopimelate decarboxylase 4 417 4.6E-138 T 28-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CO689_RS12480 1858b1132f4350edb6a2d28feb1821df 422 SUPERFAMILY SSF51419 25 287 1.6E-78 T 28-03-2018 IPR029066 PLP-binding barrel CO689_RS12215 f3da7c317c742ee83f987b24b1fd0ca2 541 ProSitePatterns PS01303 BCCT family of transporters signature. 315 324 - T 28-03-2018 IPR018093 BCCT transporter, conserved site GO:0005215|GO:0006810|GO:0016020 CO689_RS12215 f3da7c317c742ee83f987b24b1fd0ca2 541 Pfam PF02028 BCCT, betaine/carnitine/choline family transporter 13 495 3.4E-185 T 28-03-2018 IPR000060 BCCT transporter family GO:0005215|GO:0006810|GO:0016020 CO689_RS12215 f3da7c317c742ee83f987b24b1fd0ca2 541 TIGRFAM TIGR00842 bcct: transporter, betaine/carnitine/choline transporter (BCCT) family 51 495 3.7E-157 T 28-03-2018 IPR000060 BCCT transporter family GO:0005215|GO:0006810|GO:0016020 CO689_RS04630 c0caffdf4792fc00afa72191bef116dd 498 ProSitePatterns PS00933 FGGY family of carbohydrate kinases signature 1. 130 142 - T 28-03-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 CO689_RS04630 c0caffdf4792fc00afa72191bef116dd 498 ProSitePatterns PS00445 FGGY family of carbohydrate kinases signature 2. 354 374 - T 28-03-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 CO689_RS04630 c0caffdf4792fc00afa72191bef116dd 498 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 6 245 5.6E-67 T 28-03-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 CO689_RS04630 c0caffdf4792fc00afa72191bef116dd 498 SUPERFAMILY SSF53067 247 488 9.71E-65 T 28-03-2018 CO689_RS04630 c0caffdf4792fc00afa72191bef116dd 498 PIRSF PIRSF000538 3 494 3.8E-147 T 28-03-2018 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 CO689_RS04630 c0caffdf4792fc00afa72191bef116dd 498 SUPERFAMILY SSF53067 6 248 7.17E-68 T 28-03-2018 CO689_RS04630 c0caffdf4792fc00afa72191bef116dd 498 Gene3D G3DSA:3.30.420.40 243 498 5.4E-62 T 28-03-2018 CO689_RS04630 c0caffdf4792fc00afa72191bef116dd 498 Gene3D G3DSA:3.30.420.40 1 242 4.2E-71 T 28-03-2018 CO689_RS04630 c0caffdf4792fc00afa72191bef116dd 498 TIGRFAM TIGR01312 XylB: xylulokinase 7 484 2.2E-165 T 28-03-2018 IPR006000 Xylulokinase GO:0004856|GO:0005997 KEGG: 00040+2.7.1.17 CO689_RS04630 c0caffdf4792fc00afa72191bef116dd 498 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 254 441 3.1E-32 T 28-03-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 CO689_RS01330 cd02c618337c8742bdf67bf80381d544 167 SUPERFAMILY SSF54909 66 140 1.72E-6 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel CO689_RS01330 cd02c618337c8742bdf67bf80381d544 167 Gene3D G3DSA:3.30.70.100 64 156 1.0E-5 T 28-03-2018 CO689_RS08050 ce7e86e2ca45a7b0e065fd9a79275b74 1212 Pfam PF04983 RNA polymerase Rpb1, domain 3 478 667 1.0E-33 T 28-03-2018 IPR007066 RNA polymerase Rpb1, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CO689_RS08050 ce7e86e2ca45a7b0e065fd9a79275b74 1212 Hamap MF_01322 DNA-directed RNA polymerase subunit beta' [rpoC]. 4 1196 18.567 T 28-03-2018 IPR012754 DNA-directed RNA polymerase, subunit beta-prime GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CO689_RS08050 ce7e86e2ca45a7b0e065fd9a79275b74 1212 Pfam PF04998 RNA polymerase Rpb1, domain 5 774 1134 4.3E-69 T 28-03-2018 IPR007081 RNA polymerase Rpb1, domain 5 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CO689_RS08050 ce7e86e2ca45a7b0e065fd9a79275b74 1212 Pfam PF04997 RNA polymerase Rpb1, domain 1 6 331 7.1E-88 T 28-03-2018 IPR007080 RNA polymerase Rpb1, domain 1 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CO689_RS08050 ce7e86e2ca45a7b0e065fd9a79275b74 1212 SUPERFAMILY SSF64484 5 1185 0.0 T 28-03-2018 CO689_RS08050 ce7e86e2ca45a7b0e065fd9a79275b74 1212 Gene3D G3DSA:2.40.40.20 335 477 2.1E-38 T 28-03-2018 CO689_RS08050 ce7e86e2ca45a7b0e065fd9a79275b74 1212 Pfam PF00623 RNA polymerase Rpb1, domain 2 333 474 2.6E-38 T 28-03-2018 IPR000722 RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CO689_RS08050 ce7e86e2ca45a7b0e065fd9a79275b74 1212 TIGRFAM TIGR02386 rpoC_TIGR: DNA-directed RNA polymerase, beta' subunit 10 1185 0.0 T 28-03-2018 IPR012754 DNA-directed RNA polymerase, subunit beta-prime GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CO689_RS08050 ce7e86e2ca45a7b0e065fd9a79275b74 1212 SMART SM00663 224 503 1.5E-181 T 28-03-2018 IPR006592 RNA polymerase, N-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CO689_RS08050 ce7e86e2ca45a7b0e065fd9a79275b74 1212 Pfam PF05000 RNA polymerase Rpb1, domain 4 696 763 5.9E-15 T 28-03-2018 IPR007083 RNA polymerase Rpb1, domain 4 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CO689_RS08050 ce7e86e2ca45a7b0e065fd9a79275b74 1212 Gene3D G3DSA:2.40.50.100 914 1033 7.3E-40 T 28-03-2018 CO689_RS01340 cb5e8d745eface6e9c8d7aacfff9506f 245 SUPERFAMILY SSF52540 3 228 4.0E-60 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CO689_RS01340 cb5e8d745eface6e9c8d7aacfff9506f 245 Gene3D G3DSA:3.40.50.300 1 231 3.8E-60 T 28-03-2018 CO689_RS01340 cb5e8d745eface6e9c8d7aacfff9506f 245 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CO689_RS01340 cb5e8d745eface6e9c8d7aacfff9506f 245 Pfam PF00005 ABC transporter 19 161 1.9E-30 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CO689_RS01340 cb5e8d745eface6e9c8d7aacfff9506f 245 SMART SM00382 27 209 6.9E-10 T 28-03-2018 IPR003593 AAA+ ATPase domain CO689_RS12235 d47922635f4641796a736658fa1773be 202 Pfam PF02660 Glycerol-3-phosphate acyltransferase 9 191 1.3E-52 T 28-03-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 CO689_RS12235 d47922635f4641796a736658fa1773be 202 Hamap MF_01043 Glycerol-3-phosphate acyltransferase [plsY]. 5 200 20.8 T 28-03-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 CO689_RS12235 d47922635f4641796a736658fa1773be 202 TIGRFAM TIGR00023 TIGR00023: acyl-phosphate glycerol 3-phosphate acyltransferase 1 201 2.2E-59 T 28-03-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 CO689_RS12235 d47922635f4641796a736658fa1773be 202 SMART SM01207 8 192 2.6E-80 T 28-03-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 CO689_RS10875 a69d59a4434875a12c92ace675097f8c 468 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 140 158 4.1E-41 T 28-03-2018 CO689_RS10875 a69d59a4434875a12c92ace675097f8c 468 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 265 281 4.1E-41 T 28-03-2018 CO689_RS10875 a69d59a4434875a12c92ace675097f8c 468 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 12 31 4.1E-41 T 28-03-2018 CO689_RS10875 a69d59a4434875a12c92ace675097f8c 468 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 294 316 4.1E-41 T 28-03-2018 CO689_RS10875 a69d59a4434875a12c92ace675097f8c 468 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 178 196 4.1E-41 T 28-03-2018 CO689_RS10875 a69d59a4434875a12c92ace675097f8c 468 Gene3D G3DSA:3.50.50.60 239 340 2.2E-7 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CO689_RS10875 a69d59a4434875a12c92ace675097f8c 468 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 266 280 9.2E-77 T 28-03-2018 CO689_RS10875 a69d59a4434875a12c92ace675097f8c 468 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 344 365 9.2E-77 T 28-03-2018 CO689_RS10875 a69d59a4434875a12c92ace675097f8c 468 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 43 58 9.2E-77 T 28-03-2018 CO689_RS10875 a69d59a4434875a12c92ace675097f8c 468 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 11 33 9.2E-77 T 28-03-2018 CO689_RS10875 a69d59a4434875a12c92ace675097f8c 468 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 409 424 9.2E-77 T 28-03-2018 CO689_RS10875 a69d59a4434875a12c92ace675097f8c 468 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 143 152 9.2E-77 T 28-03-2018 CO689_RS10875 a69d59a4434875a12c92ace675097f8c 468 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 431 451 9.2E-77 T 28-03-2018 CO689_RS10875 a69d59a4434875a12c92ace675097f8c 468 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 178 203 9.2E-77 T 28-03-2018 CO689_RS10875 a69d59a4434875a12c92ace675097f8c 468 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 309 316 9.2E-77 T 28-03-2018 CO689_RS10875 a69d59a4434875a12c92ace675097f8c 468 PIRSF PIRSF000350 3 457 3.8E-98 T 28-03-2018 CO689_RS10875 a69d59a4434875a12c92ace675097f8c 468 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 348 456 8.2E-36 T 28-03-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 CO689_RS10875 a69d59a4434875a12c92ace675097f8c 468 Gene3D G3DSA:3.30.390.30 341 463 1.1E-40 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CO689_RS10875 a69d59a4434875a12c92ace675097f8c 468 Gene3D G3DSA:1.10.287.990 55 109 3.3E-22 T 28-03-2018 CO689_RS10875 a69d59a4434875a12c92ace675097f8c 468 Gene3D G3DSA:3.50.50.60 119 238 6.0E-30 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CO689_RS10875 a69d59a4434875a12c92ace675097f8c 468 SUPERFAMILY SSF55424 345 466 5.33E-40 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CO689_RS10875 a69d59a4434875a12c92ace675097f8c 468 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 44 54 - T 28-03-2018 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 CO689_RS10875 a69d59a4434875a12c92ace675097f8c 468 TIGRFAM TIGR01350 lipoamide_DH: dihydrolipoyl dehydrogenase 10 466 3.9E-172 T 28-03-2018 IPR006258 Dihydrolipoamide dehydrogenase GO:0004148|GO:0050660|GO:0055114 KEGG: 00010+1.8.1.4|KEGG: 00020+1.8.1.4|KEGG: 00260+1.8.1.4|KEGG: 00280+1.8.1.4|KEGG: 00620+1.8.1.4|KEGG: 00640+1.8.1.4|MetaCyc: PWY-5046|MetaCyc: PWY-5084|Reactome: R-HSA-204174|Reactome: R-HSA-389661|Reactome: R-HSA-5362517|Reactome: R-HSA-6783984|Reactome: R-HSA-70268|Reactome: R-HSA-70895|Reactome: R-HSA-71064|Reactome: R-HSA-71403 CO689_RS10875 a69d59a4434875a12c92ace675097f8c 468 Gene3D G3DSA:3.50.50.60 4 54 5.0E-11 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CO689_RS10875 a69d59a4434875a12c92ace675097f8c 468 SUPERFAMILY SSF51905 7 338 8.91E-64 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CO689_RS10875 a69d59a4434875a12c92ace675097f8c 468 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 11 329 2.6E-73 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CO689_RS00950 0270b65f5702ae35413975b9ec9547e1 555 SUPERFAMILY SSF52540 6 553 3.19E-237 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CO689_RS00950 0270b65f5702ae35413975b9ec9547e1 555 Hamap MF_01543 Formate--tetrahydrofolate ligase [fhs]. 3 555 48.3 T 28-03-2018 IPR000559 Formate-tetrahydrofolate ligase, FTHFS GO:0004329|GO:0005524 KEGG: 00670+6.3.4.3|KEGG: 00720+6.3.4.3|MetaCyc: PWY-1722|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 CO689_RS00950 0270b65f5702ae35413975b9ec9547e1 555 ProSitePatterns PS00721 Formate--tetrahydrofolate ligase signature 1. 103 113 - T 28-03-2018 IPR020628 Formate-tetrahydrofolate ligase, FTHFS, conserved site GO:0005524 KEGG: 00670+6.3.4.3|KEGG: 00720+6.3.4.3|MetaCyc: PWY-1722|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 CO689_RS00950 0270b65f5702ae35413975b9ec9547e1 555 Gene3D G3DSA:3.10.410.10 443 531 8.9E-40 T 28-03-2018 CO689_RS00950 0270b65f5702ae35413975b9ec9547e1 555 Gene3D G3DSA:3.40.50.300 14 232 1.1E-90 T 28-03-2018 CO689_RS00950 0270b65f5702ae35413975b9ec9547e1 555 Gene3D G3DSA:3.40.50.300 233 441 1.9E-75 T 28-03-2018 CO689_RS00950 0270b65f5702ae35413975b9ec9547e1 555 ProSitePatterns PS00722 Formate--tetrahydrofolate ligase signature 2. 328 339 - T 28-03-2018 IPR020628 Formate-tetrahydrofolate ligase, FTHFS, conserved site GO:0005524 KEGG: 00670+6.3.4.3|KEGG: 00720+6.3.4.3|MetaCyc: PWY-1722|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 CO689_RS00950 0270b65f5702ae35413975b9ec9547e1 555 Pfam PF01268 Formate--tetrahydrofolate ligase 5 555 5.4E-264 T 28-03-2018 IPR000559 Formate-tetrahydrofolate ligase, FTHFS GO:0004329|GO:0005524 KEGG: 00670+6.3.4.3|KEGG: 00720+6.3.4.3|MetaCyc: PWY-1722|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 CO689_RS13075 d20d690f3c9c109ab6678aa1ebb0e03d 364 Gene3D G3DSA:2.40.30.110 281 358 1.7E-19 T 28-03-2018 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 CO689_RS13075 d20d690f3c9c109ab6678aa1ebb0e03d 364 Gene3D G3DSA:3.30.1360.120 5 135 6.8E-34 T 28-03-2018 CO689_RS13075 d20d690f3c9c109ab6678aa1ebb0e03d 364 SUPERFAMILY SSF101790 274 359 2.62E-21 T 28-03-2018 IPR029043 Glycine cleavage T-protein/YgfZ, C-terminal domain CO689_RS13075 d20d690f3c9c109ab6678aa1ebb0e03d 364 PIRSF PIRSF006487 1 363 2.2E-100 T 28-03-2018 CO689_RS13075 d20d690f3c9c109ab6678aa1ebb0e03d 364 TIGRFAM TIGR00528 gcvT: glycine cleavage system T protein 5 360 3.1E-133 T 28-03-2018 IPR006223 Glycine cleavage system T protein GO:0004047|GO:0006546 KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10|Reactome: R-HSA-6783984 CO689_RS13075 d20d690f3c9c109ab6678aa1ebb0e03d 364 Gene3D G3DSA:3.30.1360.120 136 236 6.3E-28 T 28-03-2018 CO689_RS13075 d20d690f3c9c109ab6678aa1ebb0e03d 364 Pfam PF08669 Glycine cleavage T-protein C-terminal barrel domain 267 358 3.0E-23 T 28-03-2018 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 CO689_RS13075 d20d690f3c9c109ab6678aa1ebb0e03d 364 Pfam PF01571 Aminomethyltransferase folate-binding domain 10 258 4.2E-95 T 28-03-2018 IPR006222 Glycine cleavage T-protein-like, N-terminal CO689_RS13075 d20d690f3c9c109ab6678aa1ebb0e03d 364 SUPERFAMILY SSF103025 4 281 2.04E-95 T 28-03-2018 CO689_RS13075 d20d690f3c9c109ab6678aa1ebb0e03d 364 Hamap MF_00259 Aminomethyltransferase [gcvT]. 4 364 46.285 T 28-03-2018 IPR022903 Glycine cleavage system T protein, bacteria GO:0004047|GO:0006546 KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 CO689_RS13075 d20d690f3c9c109ab6678aa1ebb0e03d 364 Gene3D G3DSA:4.10.1250.10 237 280 2.3E-11 T 28-03-2018 CO689_RS08615 21d34c57b2f719b543fbfc8d3ee8bdd3 163 SUPERFAMILY SSF51182 2 158 2.16E-57 T 28-03-2018 IPR011051 RmlC-like cupin domain CO689_RS08615 21d34c57b2f719b543fbfc8d3ee8bdd3 163 Pfam PF06172 Cupin superfamily (DUF985) 7 137 7.1E-45 T 28-03-2018 IPR009327 Cupin domain of unknown function DUF985 CO689_RS08615 21d34c57b2f719b543fbfc8d3ee8bdd3 163 Gene3D G3DSA:2.60.120.10 1 159 1.4E-57 T 28-03-2018 IPR014710 RmlC-like jelly roll fold CO689_RS11660 3a68c8a7c134992f77a3bcc833244720 179 SUPERFAMILY SSF56235 5 178 1.61E-58 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CO689_RS11660 3a68c8a7c134992f77a3bcc833244720 179 Gene3D G3DSA:3.60.20.10 8 179 2.5E-28 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CO689_RS11660 3a68c8a7c134992f77a3bcc833244720 179 Hamap MF_00248 ATP-dependent protease subunit HslV [hslV]. 7 179 40.599 T 28-03-2018 IPR022281 ATP-dependent protease, HslV subunit GO:0004298|GO:0006508|GO:0009376 CO689_RS11660 3a68c8a7c134992f77a3bcc833244720 179 PIRSF PIRSF039093 1 179 1.1E-85 T 28-03-2018 IPR022281 ATP-dependent protease, HslV subunit GO:0004298|GO:0006508|GO:0009376 CO689_RS11660 3a68c8a7c134992f77a3bcc833244720 179 TIGRFAM TIGR03692 ATP_dep_HslV: ATP-dependent protease HslVU, peptidase subunit 8 179 1.0E-83 T 28-03-2018 IPR022281 ATP-dependent protease, HslV subunit GO:0004298|GO:0006508|GO:0009376 CO689_RS11660 3a68c8a7c134992f77a3bcc833244720 179 Pfam PF00227 Proteasome subunit 6 177 5.0E-27 T 28-03-2018 IPR001353 Proteasome, subunit alpha/beta GO:0004298|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-446652|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8941858|Reactome: R-HSA-8951664|Reactome: R-HSA-983168 CO689_RS10525 08e750761221f8dd7f6c50078545002c 559 SUPERFAMILY SSF52467 169 355 5.17E-6 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CO689_RS10525 08e750761221f8dd7f6c50078545002c 559 Gene3D G3DSA:3.40.50.970 355 536 5.0E-21 T 28-03-2018 CO689_RS10525 08e750761221f8dd7f6c50078545002c 559 Hamap MF_01659 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase [menD]. 5 551 32.903 T 28-03-2018 IPR004433 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase GO:0009234|GO:0030976|GO:0070204 KEGG: 00130+2.2.1.9|MetaCyc: PWY-5837 CO689_RS10525 08e750761221f8dd7f6c50078545002c 559 SUPERFAMILY SSF52518 376 519 1.23E-20 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CO689_RS10525 08e750761221f8dd7f6c50078545002c 559 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 421 485 2.7E-5 T 28-03-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 CO689_RS10525 08e750761221f8dd7f6c50078545002c 559 SUPERFAMILY SSF52518 15 182 1.93E-33 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CO689_RS10525 08e750761221f8dd7f6c50078545002c 559 PIRSF PIRSF004983 2 558 5.0E-171 T 28-03-2018 IPR004433 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase GO:0009234|GO:0030976|GO:0070204 KEGG: 00130+2.2.1.9|MetaCyc: PWY-5837 CO689_RS10525 08e750761221f8dd7f6c50078545002c 559 Gene3D G3DSA:3.40.50.970 3 205 2.9E-50 T 28-03-2018 CO689_RS10525 08e750761221f8dd7f6c50078545002c 559 TIGRFAM TIGR00173 menD: 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase 13 430 6.6E-124 T 28-03-2018 IPR004433 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase GO:0009234|GO:0030976|GO:0070204 KEGG: 00130+2.2.1.9|MetaCyc: PWY-5837 CO689_RS10525 08e750761221f8dd7f6c50078545002c 559 Gene3D G3DSA:3.40.50.1220 206 354 3.8E-19 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CO689_RS10525 08e750761221f8dd7f6c50078545002c 559 Pfam PF16582 Middle domain of thiamine pyrophosphate 186 389 1.6E-10 T 28-03-2018 IPR032264 Menaquinone biosynthesis protein MenD, middle domain KEGG: 00130+2.2.1.9|MetaCyc: PWY-5837 CO689_RS10525 08e750761221f8dd7f6c50078545002c 559 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 15 179 7.2E-31 T 28-03-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 CO689_RS07300 0549227ee69df9e2943624d3bf01fe51 253 Gene3D G3DSA:3.40.1010.10 1 126 2.5E-37 T 28-03-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CO689_RS07300 0549227ee69df9e2943624d3bf01fe51 253 ProSitePatterns PS00839 Uroporphyrin-III C-methyltransferase signature 1. 7 21 - T 28-03-2018 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 CO689_RS07300 0549227ee69df9e2943624d3bf01fe51 253 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 3 214 3.0E-48 T 28-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CO689_RS07300 0549227ee69df9e2943624d3bf01fe51 253 SUPERFAMILY SSF53790 1 245 2.36E-79 T 28-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CO689_RS07300 0549227ee69df9e2943624d3bf01fe51 253 ProSitePatterns PS00840 Uroporphyrin-III C-methyltransferase signature 2. 82 115 - T 28-03-2018 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 CO689_RS07300 0549227ee69df9e2943624d3bf01fe51 253 Gene3D G3DSA:3.30.950.10 127 253 5.7E-39 T 28-03-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CO689_RS07300 0549227ee69df9e2943624d3bf01fe51 253 TIGRFAM TIGR01469 cobA_cysG_Cterm: uroporphyrinogen-III C-methyltransferase 2 236 1.4E-90 T 28-03-2018 IPR006366 Uroporphyrin-III C-methyltransferase GO:0006779|GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 CO689_RS04520 b166229d1bd9e7176febb39454c14710 397 Hamap MF_00740 Phosphopentomutase [deoB]. 5 389 52.466 T 28-03-2018 IPR010045 Phosphopentomutase GO:0000287|GO:0005737|GO:0008973|GO:0009117|GO:0043094 KEGG: 00030+5.4.2.7|KEGG: 00230+5.4.2.7|MetaCyc: PWY-7180 CO689_RS04520 b166229d1bd9e7176febb39454c14710 397 Pfam PF01676 Metalloenzyme superfamily 6 379 9.2E-40 T 28-03-2018 IPR006124 Metalloenzyme GO:0003824|GO:0046872 CO689_RS04520 b166229d1bd9e7176febb39454c14710 397 SUPERFAMILY SSF53649 218 391 7.2E-75 T 28-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 CO689_RS04520 b166229d1bd9e7176febb39454c14710 397 SUPERFAMILY SSF53649 5 101 7.2E-75 T 28-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 CO689_RS04520 b166229d1bd9e7176febb39454c14710 397 PIRSF PIRSF001491 4 393 1.9E-160 T 28-03-2018 IPR010045 Phosphopentomutase GO:0000287|GO:0005737|GO:0008973|GO:0009117|GO:0043094 KEGG: 00030+5.4.2.7|KEGG: 00230+5.4.2.7|MetaCyc: PWY-7180 CO689_RS04520 b166229d1bd9e7176febb39454c14710 397 TIGRFAM TIGR01696 deoB: phosphopentomutase 7 387 6.8E-212 T 28-03-2018 IPR010045 Phosphopentomutase GO:0000287|GO:0005737|GO:0008973|GO:0009117|GO:0043094 KEGG: 00030+5.4.2.7|KEGG: 00230+5.4.2.7|MetaCyc: PWY-7180 CO689_RS04520 b166229d1bd9e7176febb39454c14710 397 SUPERFAMILY SSF143856 101 217 8.63E-50 T 28-03-2018 IPR024052 Phosphopentomutase DeoB cap domain GO:0008973 KEGG: 00030+5.4.2.7|KEGG: 00230+5.4.2.7|MetaCyc: PWY-7180 CO689_RS04520 b166229d1bd9e7176febb39454c14710 397 Gene3D G3DSA:3.30.70.1250 100 211 5.4E-54 T 28-03-2018 IPR024052 Phosphopentomutase DeoB cap domain GO:0008973 KEGG: 00030+5.4.2.7|KEGG: 00230+5.4.2.7|MetaCyc: PWY-7180 CO689_RS04520 b166229d1bd9e7176febb39454c14710 397 Gene3D G3DSA:3.40.720.10 212 391 1.8E-16 T 28-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 CO689_RS11495 4ca02e21975e5b1c43baed6511cea9ce 548 Pfam PF13684 Dihydroxyacetone kinase family 237 548 1.0E-118 T 28-03-2018 IPR033470 Uncharacterised protein, DhaK domain CO689_RS11495 4ca02e21975e5b1c43baed6511cea9ce 548 SMART SM01121 236 548 8.4E-174 T 28-03-2018 IPR033470 Uncharacterised protein, DhaK domain CO689_RS11495 4ca02e21975e5b1c43baed6511cea9ce 548 SUPERFAMILY SSF101473 3 199 1.83E-45 T 28-03-2018 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 CO689_RS11495 4ca02e21975e5b1c43baed6511cea9ce 548 SMART SM01120 35 200 6.7E-70 T 28-03-2018 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 CO689_RS11495 4ca02e21975e5b1c43baed6511cea9ce 548 Pfam PF02734 DAK2 domain 35 198 8.6E-41 T 28-03-2018 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 CO689_RS11495 4ca02e21975e5b1c43baed6511cea9ce 548 TIGRFAM TIGR03599 YloV: DAK2 domain fusion protein YloV 10 548 1.5E-205 T 28-03-2018 IPR019986 DAK2 domain-containing protein YloV CO689_RS11740 2332dff18505f19071a68decc9699c12 711 Gene3D G3DSA:2.40.30.10 384 478 3.1E-14 T 28-03-2018 CO689_RS11740 2332dff18505f19071a68decc9699c12 711 Gene3D G3DSA:2.40.30.10 614 711 5.4E-32 T 28-03-2018 CO689_RS11740 2332dff18505f19071a68decc9699c12 711 ProSitePatterns PS01176 Initiation factor 2 signature. 664 686 - T 28-03-2018 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 CO689_RS11740 2332dff18505f19071a68decc9699c12 711 SUPERFAMILY SSF50447 614 711 3.74E-35 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain CO689_RS11740 2332dff18505f19071a68decc9699c12 711 Gene3D G3DSA:3.40.50.10050 511 592 1.0E-27 T 28-03-2018 IPR023115 Translation initiation factor IF- 2, domain 3 CO689_RS11740 2332dff18505f19071a68decc9699c12 711 Gene3D G3DSA:3.40.50.300 210 383 5.0E-41 T 28-03-2018 CO689_RS11740 2332dff18505f19071a68decc9699c12 711 Pfam PF04760 Translation initiation factor IF-2, N-terminal region 1 51 3.5E-14 T 28-03-2018 IPR006847 Translation initiation factor IF-2, N-terminal CO689_RS11740 2332dff18505f19071a68decc9699c12 711 Pfam PF04760 Translation initiation factor IF-2, N-terminal region 137 186 2.3E-16 T 28-03-2018 IPR006847 Translation initiation factor IF-2, N-terminal CO689_RS11740 2332dff18505f19071a68decc9699c12 711 TIGRFAM TIGR00487 IF-2: translation initiation factor IF-2 128 711 2.6E-275 T 28-03-2018 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 CO689_RS11740 2332dff18505f19071a68decc9699c12 711 SUPERFAMILY SSF52156 490 620 6.02E-40 T 28-03-2018 IPR023115 Translation initiation factor IF- 2, domain 3 CO689_RS11740 2332dff18505f19071a68decc9699c12 711 SUPERFAMILY SSF50447 385 468 1.09E-24 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain CO689_RS11740 2332dff18505f19071a68decc9699c12 711 Gene3D G3DSA:3.30.56.50 4 46 8.4E-12 T 28-03-2018 CO689_RS11740 2332dff18505f19071a68decc9699c12 711 Gene3D G3DSA:3.30.56.50 138 179 2.0E-11 T 28-03-2018 CO689_RS11740 2332dff18505f19071a68decc9699c12 711 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 215 372 3.5E-39 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 CO689_RS11740 2332dff18505f19071a68decc9699c12 711 SUPERFAMILY SSF52540 206 386 2.29E-54 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CO689_RS11740 2332dff18505f19071a68decc9699c12 711 Pfam PF00009 Elongation factor Tu GTP binding domain 218 374 3.3E-36 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CO689_RS11740 2332dff18505f19071a68decc9699c12 711 Hamap MF_00100_B Translation initiation factor IF-2 [infB]. 3 711 17.514 T 28-03-2018 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 CO689_RS11740 2332dff18505f19071a68decc9699c12 711 Pfam PF11987 Translation-initiation factor 2 499 603 6.9E-38 T 28-03-2018 IPR023115 Translation initiation factor IF- 2, domain 3 CO689_RS02320 f842d2584fba4adca04baad577887390 356 Hamap MF_00047 D-alanine--D-alanine ligase [ddl]. 4 342 40.552 T 28-03-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CO689_RS02320 f842d2584fba4adca04baad577887390 356 SUPERFAMILY SSF52440 3 128 2.49E-33 T 28-03-2018 IPR016185 Pre-ATP-grasp domain CO689_RS02320 f842d2584fba4adca04baad577887390 356 SUPERFAMILY SSF56059 129 348 2.42E-58 T 28-03-2018 CO689_RS02320 f842d2584fba4adca04baad577887390 356 Pfam PF01820 D-ala D-ala ligase N-terminus 5 118 5.7E-30 T 28-03-2018 IPR011127 D-alanine--D-alanine ligase, N-terminal domain KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CO689_RS02320 f842d2584fba4adca04baad577887390 356 Gene3D G3DSA:3.40.50.20 1 139 1.5E-41 T 28-03-2018 CO689_RS02320 f842d2584fba4adca04baad577887390 356 ProSitePatterns PS00843 D-alanine--D-alanine ligase signature 1. 96 107 - T 28-03-2018 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CO689_RS02320 f842d2584fba4adca04baad577887390 356 Gene3D G3DSA:3.30.1490.20 145 204 1.6E-19 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CO689_RS02320 f842d2584fba4adca04baad577887390 356 PIRSF PIRSF039102 1 350 4.5E-110 T 28-03-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CO689_RS02320 f842d2584fba4adca04baad577887390 356 TIGRFAM TIGR01205 D_ala_D_alaTIGR: D-alanine--D-alanine ligase 6 341 4.0E-106 T 28-03-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CO689_RS02320 f842d2584fba4adca04baad577887390 356 Pfam PF07478 D-ala D-ala ligase C-terminus 136 339 1.8E-75 T 28-03-2018 IPR011095 D-alanine--D-alanine ligase, C-terminal GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CO689_RS02320 f842d2584fba4adca04baad577887390 356 Gene3D G3DSA:3.30.470.20 205 351 2.9E-39 T 28-03-2018 CO689_RS03245 c654dad888e502ea73308a827f293335 382 Pfam PF07690 Major Facilitator Superfamily 3 282 1.3E-35 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CO689_RS03245 c654dad888e502ea73308a827f293335 382 SUPERFAMILY SSF103473 3 376 3.4E-51 T 28-03-2018 IPR020846 Major facilitator superfamily domain CO689_RS03245 c654dad888e502ea73308a827f293335 382 Gene3D G3DSA:1.20.1250.20 1 188 5.4E-26 T 28-03-2018 CO689_RS03245 c654dad888e502ea73308a827f293335 382 Gene3D G3DSA:1.20.1250.20 191 381 4.9E-21 T 28-03-2018 CO689_RS12510 bf2c0e5e716590bd137de2b7fbfbe775 375 PIRSF PIRSF026508 1 375 1.9E-115 T 28-03-2018 IPR008863 Toxic anion resistance CO689_RS12510 bf2c0e5e716590bd137de2b7fbfbe775 375 Pfam PF05816 Toxic anion resistance protein (TelA) 38 367 8.7E-121 T 28-03-2018 IPR008863 Toxic anion resistance CO689_RS08900 fc12436ad7b13bbd5d33cb3ce9611b8b 197 PRINTS PR00097 Anthranilate synthase component II signature 75 86 5.8E-30 T 28-03-2018 CO689_RS08900 fc12436ad7b13bbd5d33cb3ce9611b8b 197 PRINTS PR00097 Anthranilate synthase component II signature 120 132 5.8E-30 T 28-03-2018 CO689_RS08900 fc12436ad7b13bbd5d33cb3ce9611b8b 197 PRINTS PR00097 Anthranilate synthase component II signature 2 16 5.8E-30 T 28-03-2018 CO689_RS08900 fc12436ad7b13bbd5d33cb3ce9611b8b 197 PRINTS PR00097 Anthranilate synthase component II signature 100 108 5.8E-30 T 28-03-2018 CO689_RS08900 fc12436ad7b13bbd5d33cb3ce9611b8b 197 PRINTS PR00097 Anthranilate synthase component II signature 48 57 5.8E-30 T 28-03-2018 CO689_RS08900 fc12436ad7b13bbd5d33cb3ce9611b8b 197 PRINTS PR00097 Anthranilate synthase component II signature 165 178 5.8E-30 T 28-03-2018 CO689_RS08900 fc12436ad7b13bbd5d33cb3ce9611b8b 197 Pfam PF00117 Glutamine amidotransferase class-I 4 187 6.7E-44 T 28-03-2018 IPR017926 Glutamine amidotransferase CO689_RS08900 fc12436ad7b13bbd5d33cb3ce9611b8b 197 Gene3D G3DSA:3.40.50.880 1 192 2.3E-51 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CO689_RS08900 fc12436ad7b13bbd5d33cb3ce9611b8b 197 SUPERFAMILY SSF52317 1 190 1.41E-48 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CO689_RS08900 fc12436ad7b13bbd5d33cb3ce9611b8b 197 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 75 91 1.0E-5 T 28-03-2018 CO689_RS08900 fc12436ad7b13bbd5d33cb3ce9611b8b 197 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 45 59 1.0E-5 T 28-03-2018 CO689_RS08900 fc12436ad7b13bbd5d33cb3ce9611b8b 197 TIGRFAM TIGR00566 trpG_papA: glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase 1 187 1.4E-53 T 28-03-2018 IPR006221 Anthranilate synthase/para-aminobenzoate synthase like domain GO:0008152 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CO689_RS08900 fc12436ad7b13bbd5d33cb3ce9611b8b 197 PRINTS PR00096 Glutamine amidotransferase superfamily signature 75 86 1.0E-13 T 28-03-2018 CO689_RS08900 fc12436ad7b13bbd5d33cb3ce9611b8b 197 PRINTS PR00096 Glutamine amidotransferase superfamily signature 48 57 1.0E-13 T 28-03-2018 CO689_RS08900 fc12436ad7b13bbd5d33cb3ce9611b8b 197 PRINTS PR00096 Glutamine amidotransferase superfamily signature 165 178 1.0E-13 T 28-03-2018 CO689_RS10055 bcb3e0bc831eb5930d9990bfcaf031a0 514 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 284 291 - T 28-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 CO689_RS10055 bcb3e0bc831eb5930d9990bfcaf031a0 514 Pfam PF00171 Aldehyde dehydrogenase family 49 507 3.2E-147 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CO689_RS10055 bcb3e0bc831eb5930d9990bfcaf031a0 514 SUPERFAMILY SSF53720 3 511 2.49E-149 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CO689_RS10055 bcb3e0bc831eb5930d9990bfcaf031a0 514 Gene3D G3DSA:3.40.605.10 21 300 5.1E-80 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CO689_RS10055 bcb3e0bc831eb5930d9990bfcaf031a0 514 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 312 323 - T 28-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 CO689_RS10055 bcb3e0bc831eb5930d9990bfcaf031a0 514 TIGRFAM TIGR01237 D1pyr5carbox2: putative delta-1-pyrroline-5-carboxylate dehydrogenase 4 513 3.1E-231 T 28-03-2018 IPR005932 Putative 1-pyrroline-5-carboxylate dehydrogenase, Bacillales KEGG: 00250+1.2.1.88|KEGG: 00330+1.2.1.88|MetaCyc: PWY-6853 CO689_RS10055 bcb3e0bc831eb5930d9990bfcaf031a0 514 Gene3D G3DSA:3.40.309.10 301 489 4.4E-61 T 28-03-2018 CO689_RS10110 10bb33644108c76a32e062f7b5343697 303 SUPERFAMILY SSF56529 83 299 3.66E-70 T 28-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CO689_RS10110 10bb33644108c76a32e062f7b5343697 303 Gene3D G3DSA:3.90.850.10 42 303 8.4E-73 T 28-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CO689_RS10110 10bb33644108c76a32e062f7b5343697 303 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 95 296 1.9E-62 T 28-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CO689_RS02380 15cfb9511453e71c209165bf90a0a45c 212 Hamap MF_00097 Thiamine-phosphate synthase [thiE]. 7 212 26.689 T 28-03-2018 IPR034291 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CO689_RS02380 15cfb9511453e71c209165bf90a0a45c 212 Gene3D G3DSA:3.20.20.70 2 211 1.2E-38 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CO689_RS02380 15cfb9511453e71c209165bf90a0a45c 212 SUPERFAMILY SSF51391 5 211 5.89E-60 T 28-03-2018 IPR022998 Thiamine phosphate synthase/TenI KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CO689_RS02380 15cfb9511453e71c209165bf90a0a45c 212 TIGRFAM TIGR00693 thiE: thiamine-phosphate diphosphorylase 8 206 2.2E-60 T 28-03-2018 IPR034291 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CO689_RS02380 15cfb9511453e71c209165bf90a0a45c 212 Pfam PF02581 Thiamine monophosphate synthase 9 194 1.2E-57 T 28-03-2018 IPR022998 Thiamine phosphate synthase/TenI KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CO689_RS03165 addcffad6b6d8124f7da626e8b93fbb4 261 SUPERFAMILY SSF51735 6 252 1.44E-80 T 28-03-2018 IPR016040 NAD(P)-binding domain CO689_RS03165 addcffad6b6d8124f7da626e8b93fbb4 261 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 16 251 1.2E-63 T 28-03-2018 CO689_RS03165 addcffad6b6d8124f7da626e8b93fbb4 261 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 145 173 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CO689_RS03165 addcffad6b6d8124f7da626e8b93fbb4 261 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 84 95 1.1E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CO689_RS03165 addcffad6b6d8124f7da626e8b93fbb4 261 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 158 177 1.1E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CO689_RS03165 addcffad6b6d8124f7da626e8b93fbb4 261 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 138 146 1.1E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CO689_RS03165 addcffad6b6d8124f7da626e8b93fbb4 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 132 148 6.6E-39 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CO689_RS03165 addcffad6b6d8124f7da626e8b93fbb4 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 84 95 6.6E-39 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CO689_RS03165 addcffad6b6d8124f7da626e8b93fbb4 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 214 234 6.6E-39 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CO689_RS03165 addcffad6b6d8124f7da626e8b93fbb4 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 158 177 6.6E-39 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CO689_RS03165 addcffad6b6d8124f7da626e8b93fbb4 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 6.6E-39 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CO689_RS03165 addcffad6b6d8124f7da626e8b93fbb4 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 179 196 6.6E-39 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CO689_RS03165 addcffad6b6d8124f7da626e8b93fbb4 261 Gene3D G3DSA:3.40.50.720 43 255 4.4E-61 T 28-03-2018 CO689_RS03165 addcffad6b6d8124f7da626e8b93fbb4 261 Gene3D G3DSA:3.40.50.720 1 42 6.3E-7 T 28-03-2018 CO689_RS11805 ec7751b22c395b2e2244898a1d825f11 701 SUPERFAMILY SSF55666 454 552 8.55E-30 T 28-03-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CO689_RS11805 ec7751b22c395b2e2244898a1d825f11 701 Pfam PF00575 S1 RNA binding domain 623 693 1.5E-17 T 28-03-2018 IPR003029 S1 domain GO:0003676 CO689_RS11805 ec7751b22c395b2e2244898a1d825f11 701 Hamap MF_01595 Polyribonucleotide nucleotidyltransferase [pnp]. 4 697 30.77 T 28-03-2018 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 CO689_RS11805 ec7751b22c395b2e2244898a1d825f11 701 SUPERFAMILY SSF55666 145 236 7.85E-29 T 28-03-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CO689_RS11805 ec7751b22c395b2e2244898a1d825f11 701 SMART SM00316 624 694 1.3E-24 T 28-03-2018 IPR022967 RNA-binding domain, S1 CO689_RS11805 ec7751b22c395b2e2244898a1d825f11 701 PIRSF PIRSF005499 2 701 1.9E-299 T 28-03-2018 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 CO689_RS11805 ec7751b22c395b2e2244898a1d825f11 701 Pfam PF03726 Polyribonucleotide nucleotidyltransferase, RNA binding domain 241 324 5.0E-14 T 28-03-2018 IPR015848 Polyribonucleotide nucleotidyltransferase, RNA-binding domain GO:0000175|GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 CO689_RS11805 ec7751b22c395b2e2244898a1d825f11 701 TIGRFAM TIGR03591 polynuc_phos: polyribonucleotide nucleotidyltransferase 11 694 0.0 T 28-03-2018 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 CO689_RS11805 ec7751b22c395b2e2244898a1d825f11 701 Pfam PF03725 3' exoribonuclease family, domain 2 463 531 3.9E-8 T 28-03-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CO689_RS11805 ec7751b22c395b2e2244898a1d825f11 701 Pfam PF03725 3' exoribonuclease family, domain 2 147 210 7.5E-15 T 28-03-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CO689_RS11805 ec7751b22c395b2e2244898a1d825f11 701 SUPERFAMILY SSF54211 9 144 3.09E-48 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CO689_RS11805 ec7751b22c395b2e2244898a1d825f11 701 Gene3D G3DSA:1.10.10.400 252 314 3.2E-19 T 28-03-2018 IPR015848 Polyribonucleotide nucleotidyltransferase, RNA-binding domain GO:0000175|GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 CO689_RS11805 ec7751b22c395b2e2244898a1d825f11 701 Pfam PF00013 KH domain 560 618 5.7E-9 T 28-03-2018 IPR004088 K Homology domain, type 1 GO:0003723 CO689_RS11805 ec7751b22c395b2e2244898a1d825f11 701 SUPERFAMILY SSF50249 624 697 1.64E-18 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CO689_RS11805 ec7751b22c395b2e2244898a1d825f11 701 SMART SM00322 556 621 3.6E-11 T 28-03-2018 IPR004087 K Homology domain GO:0003676 CO689_RS11805 ec7751b22c395b2e2244898a1d825f11 701 SUPERFAMILY SSF54211 300 491 3.14E-47 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CO689_RS11805 ec7751b22c395b2e2244898a1d825f11 701 Gene3D G3DSA:2.40.50.140 631 700 1.3E-21 T 28-03-2018 CO689_RS11805 ec7751b22c395b2e2244898a1d825f11 701 Gene3D G3DSA:3.30.230.70 12 251 2.0E-56 T 28-03-2018 IPR027408 PNPase/RNase PH domain Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CO689_RS11805 ec7751b22c395b2e2244898a1d825f11 701 Gene3D G3DSA:3.30.230.70 315 558 2.9E-58 T 28-03-2018 IPR027408 PNPase/RNase PH domain Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CO689_RS11805 ec7751b22c395b2e2244898a1d825f11 701 SUPERFAMILY SSF54791 559 644 9.86E-22 T 28-03-2018 IPR004088 K Homology domain, type 1 GO:0003723 CO689_RS11805 ec7751b22c395b2e2244898a1d825f11 701 Pfam PF01138 3' exoribonuclease family, domain 1 327 460 2.4E-17 T 28-03-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CO689_RS11805 ec7751b22c395b2e2244898a1d825f11 701 Pfam PF01138 3' exoribonuclease family, domain 1 15 144 1.9E-22 T 28-03-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CO689_RS11805 ec7751b22c395b2e2244898a1d825f11 701 SUPERFAMILY SSF46915 239 324 1.07E-15 T 28-03-2018 IPR015848 Polyribonucleotide nucleotidyltransferase, RNA-binding domain GO:0000175|GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 CO689_RS11805 ec7751b22c395b2e2244898a1d825f11 701 Gene3D G3DSA:3.30.1370.10 559 630 2.9E-13 T 28-03-2018 IPR004088 K Homology domain, type 1 GO:0003723 CO689_RS07565 3d39698a529b9421be5be13682211e45 206 Pfam PF02223 Thymidylate kinase 7 192 5.9E-54 T 28-03-2018 CO689_RS07565 3d39698a529b9421be5be13682211e45 206 TIGRFAM TIGR00041 DTMP_kinase: dTMP kinase 2 192 1.6E-57 T 28-03-2018 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 CO689_RS07565 3d39698a529b9421be5be13682211e45 206 SUPERFAMILY SSF52540 2 203 3.69E-57 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CO689_RS07565 3d39698a529b9421be5be13682211e45 206 Gene3D G3DSA:3.40.50.300 2 205 1.1E-54 T 28-03-2018 CO689_RS07565 3d39698a529b9421be5be13682211e45 206 Hamap MF_00165 Thymidylate kinase [tmk]. 3 202 31.324 T 28-03-2018 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 CO689_RS07565 3d39698a529b9421be5be13682211e45 206 ProSitePatterns PS01331 Thymidylate kinase signature. 89 101 - T 28-03-2018 IPR018095 Thymidylate kinase, conserved site GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 CO689_RS01775 1408ba52e70083f8ab8b8e0585564387 453 ProSitePatterns PS01231 RNA methyltransferase trmA family signature 2. 435 445 - T 28-03-2018 IPR030391 RNA methyltransferase TrmA, conserved site CO689_RS01775 1408ba52e70083f8ab8b8e0585564387 453 SUPERFAMILY SSF50249 4 61 3.08E-14 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CO689_RS01775 1408ba52e70083f8ab8b8e0585564387 453 Gene3D G3DSA:2.40.50.140 2 75 4.1E-24 T 28-03-2018 CO689_RS01775 1408ba52e70083f8ab8b8e0585564387 453 SUPERFAMILY SSF53335 68 452 7.21E-85 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CO689_RS01775 1408ba52e70083f8ab8b8e0585564387 453 Gene3D G3DSA:3.40.50.150 76 451 2.3E-63 T 28-03-2018 CO689_RS01775 1408ba52e70083f8ab8b8e0585564387 453 TIGRFAM TIGR00479 rumA: 23S rRNA (uracil-5-)-methyltransferase RumA 17 445 5.5E-161 T 28-03-2018 IPR001566 23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD GO:0003723|GO:0006396|GO:0008173 CO689_RS01775 1408ba52e70083f8ab8b8e0585564387 453 ProSitePatterns PS01230 RNA methyltransferase trmA family signature 1. 384 415 - T 28-03-2018 IPR030390 RNA methyltransferase TrmA, active site CO689_RS01775 1408ba52e70083f8ab8b8e0585564387 453 Pfam PF05958 tRNA (Uracil-5-)-methyltransferase 90 452 1.6E-21 T 28-03-2018 IPR010280 (Uracil-5)-methyltransferase family GO:0006396|GO:0008173 CO689_RS01305 6d46708ca6d22efb75b093f1b50bfbd2 366 Pfam PF02445 Quinolinate synthetase A protein 27 363 2.6E-97 T 28-03-2018 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 CO689_RS01305 6d46708ca6d22efb75b093f1b50bfbd2 366 Hamap MF_00569 Quinolinate synthase A [nadA]. 20 365 50.462 T 28-03-2018 IPR023515 Quinolinate synthase A, type 3 GO:0016765 MetaCyc: PWY-5316|MetaCyc: PWY-7342 CO689_RS01305 6d46708ca6d22efb75b093f1b50bfbd2 366 Gene3D G3DSA:3.40.50.10800 110 235 6.2E-18 T 28-03-2018 CO689_RS01305 6d46708ca6d22efb75b093f1b50bfbd2 366 SUPERFAMILY SSF142754 35 364 1.96E-86 T 28-03-2018 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 CO689_RS01305 6d46708ca6d22efb75b093f1b50bfbd2 366 Gene3D G3DSA:3.40.50.10800 236 342 2.1E-23 T 28-03-2018 CO689_RS01305 6d46708ca6d22efb75b093f1b50bfbd2 366 Gene3D G3DSA:3.40.50.10800 18 105 1.0E-15 T 28-03-2018 CO689_RS01305 6d46708ca6d22efb75b093f1b50bfbd2 366 TIGRFAM TIGR00550 nadA: quinolinate synthetase complex, A subunit 19 366 1.8E-105 T 28-03-2018 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 CO689_RS01820 cd790892e8c1022766b912d8d232610e 731 TIGRFAM TIGR01073 pcrA: ATP-dependent DNA helicase PcrA 4 727 0.0 T 28-03-2018 IPR005751 ATP-dependent DNA helicase PcrA GO:0004003|GO:0005737|GO:0006268 CO689_RS01820 cd790892e8c1022766b912d8d232610e 731 Gene3D G3DSA:3.40.50.300 386 680 1.8E-50 T 28-03-2018 CO689_RS01820 cd790892e8c1022766b912d8d232610e 731 Pfam PF13361 UvrD-like helicase C-terminal domain 276 614 3.0E-79 T 28-03-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 CO689_RS01820 cd790892e8c1022766b912d8d232610e 731 Gene3D G3DSA:3.40.50.300 281 384 1.9E-28 T 28-03-2018 CO689_RS01820 cd790892e8c1022766b912d8d232610e 731 Pfam PF00580 UvrD/REP helicase N-terminal domain 8 270 5.6E-84 T 28-03-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 CO689_RS01820 cd790892e8c1022766b912d8d232610e 731 Gene3D G3DSA:3.40.50.300 140 280 5.1E-35 T 28-03-2018 CO689_RS01820 cd790892e8c1022766b912d8d232610e 731 Gene3D G3DSA:3.40.50.300 1 139 8.8E-30 T 28-03-2018 CO689_RS01820 cd790892e8c1022766b912d8d232610e 731 SUPERFAMILY SSF52540 3 641 3.27E-183 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CO689_RS08230 141d5b613f768d0f6240baec8a497f90 515 Pfam PF00149 Calcineurin-like phosphoesterase 6 234 3.0E-7 T 28-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 CO689_RS08230 141d5b613f768d0f6240baec8a497f90 515 Gene3D G3DSA:3.90.780.10 308 515 2.7E-45 T 28-03-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CO689_RS08230 141d5b613f768d0f6240baec8a497f90 515 SUPERFAMILY SSF56300 3 306 2.95E-61 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CO689_RS08230 141d5b613f768d0f6240baec8a497f90 515 ProSitePatterns PS00786 5'-nucleotidase signature 2. 86 97 - T 28-03-2018 IPR006146 5'-Nucleotidase, conserved site GO:0000166|GO:0016788|GO:0046872 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CO689_RS08230 141d5b613f768d0f6240baec8a497f90 515 PRINTS PR01607 Apyrase family signature 2 20 8.4E-24 T 28-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CO689_RS08230 141d5b613f768d0f6240baec8a497f90 515 PRINTS PR01607 Apyrase family signature 181 198 8.4E-24 T 28-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CO689_RS08230 141d5b613f768d0f6240baec8a497f90 515 PRINTS PR01607 Apyrase family signature 217 240 8.4E-24 T 28-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CO689_RS08230 141d5b613f768d0f6240baec8a497f90 515 PRINTS PR01607 Apyrase family signature 243 263 8.4E-24 T 28-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CO689_RS08230 141d5b613f768d0f6240baec8a497f90 515 PRINTS PR01607 Apyrase family signature 362 385 8.4E-24 T 28-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CO689_RS08230 141d5b613f768d0f6240baec8a497f90 515 PRINTS PR01607 Apyrase family signature 451 470 8.4E-24 T 28-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CO689_RS08230 141d5b613f768d0f6240baec8a497f90 515 SUPERFAMILY SSF55816 305 510 1.23E-46 T 28-03-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CO689_RS08230 141d5b613f768d0f6240baec8a497f90 515 Pfam PF02872 5'-nucleotidase, C-terminal domain 309 477 3.4E-29 T 28-03-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CO689_RS08230 141d5b613f768d0f6240baec8a497f90 515 Gene3D G3DSA:3.60.21.10 2 306 1.8E-56 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CO689_RS02390 5f18e6e60724c94d5a94fba989623365 273 Gene3D G3DSA:3.40.1190.20 1 271 3.4E-55 T 28-03-2018 IPR029056 Ribokinase-like CO689_RS02390 5f18e6e60724c94d5a94fba989623365 273 TIGRFAM TIGR00097 HMP-P_kinase: hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 7 262 8.2E-93 T 28-03-2018 IPR004399 Hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase GO:0008972|GO:0009228 KEGG: 00730+2.7.1.49|MetaCyc: PWY-6910|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CO689_RS02390 5f18e6e60724c94d5a94fba989623365 273 SUPERFAMILY SSF53613 5 266 1.56E-76 T 28-03-2018 IPR029056 Ribokinase-like CO689_RS02390 5f18e6e60724c94d5a94fba989623365 273 Pfam PF08543 Phosphomethylpyrimidine kinase 14 260 2.0E-91 T 28-03-2018 IPR013749 Pyridoxamine kinase/Phosphomethylpyrimidine kinase Reactome: R-HSA-6798695|Reactome: R-HSA-964975 CO689_RS04480 81cc4492ba897a32c12d80e13efc5206 202 Gene3D G3DSA:2.40.260.10 30 202 6.6E-31 T 28-03-2018 IPR023365 Sortase domain CO689_RS04480 81cc4492ba897a32c12d80e13efc5206 202 SUPERFAMILY SSF63817 59 201 2.09E-35 T 28-03-2018 IPR023365 Sortase domain CO689_RS04480 81cc4492ba897a32c12d80e13efc5206 202 TIGRFAM TIGR01076 sortase_fam: sortase 71 200 5.2E-38 T 28-03-2018 IPR005754 Sortase family CO689_RS04480 81cc4492ba897a32c12d80e13efc5206 202 Pfam PF04203 Sortase family 73 201 7.5E-23 T 28-03-2018 IPR005754 Sortase family CO689_RS10750 614dffe7072b02af78d8ff71a696d6f4 346 Pfam PF00586 AIR synthase related protein, N-terminal domain 56 162 2.1E-15 T 28-03-2018 IPR016188 PurM-like, N-terminal domain CO689_RS10750 614dffe7072b02af78d8ff71a696d6f4 346 Gene3D G3DSA:3.30.1330.10 29 159 8.3E-52 T 28-03-2018 IPR016188 PurM-like, N-terminal domain CO689_RS10750 614dffe7072b02af78d8ff71a696d6f4 346 TIGRFAM TIGR00878 purM: phosphoribosylformylglycinamidine cyclo-ligase 5 333 5.5E-134 T 28-03-2018 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CO689_RS10750 614dffe7072b02af78d8ff71a696d6f4 346 Gene3D G3DSA:3.90.650.10 169 343 4.7E-63 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain CO689_RS10750 614dffe7072b02af78d8ff71a696d6f4 346 Pfam PF02769 AIR synthase related protein, C-terminal domain 174 337 1.2E-37 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain CO689_RS10750 614dffe7072b02af78d8ff71a696d6f4 346 SUPERFAMILY SSF55326 5 168 5.08E-49 T 28-03-2018 IPR016188 PurM-like, N-terminal domain CO689_RS10750 614dffe7072b02af78d8ff71a696d6f4 346 Hamap MF_00741 Phosphoribosylformylglycinamidine cyclo-ligase [purM]. 4 342 45.406 T 28-03-2018 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CO689_RS10750 614dffe7072b02af78d8ff71a696d6f4 346 SUPERFAMILY SSF56042 169 337 8.37E-59 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain CO689_RS11115 fe2294e928387336d7b4d4a82c0d4cec 266 ProSitePatterns PS00924 Aspartate and glutamate racemases signature 2. 180 190 - T 28-03-2018 IPR033134 Asp/Glu racemase, active site 2 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CO689_RS11115 fe2294e928387336d7b4d4a82c0d4cec 266 Gene3D G3DSA:3.40.50.1860 115 266 1.2E-39 T 28-03-2018 CO689_RS11115 fe2294e928387336d7b4d4a82c0d4cec 266 SUPERFAMILY SSF53681 108 262 2.29E-36 T 28-03-2018 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CO689_RS11115 fe2294e928387336d7b4d4a82c0d4cec 266 SUPERFAMILY SSF53681 4 106 1.11E-35 T 28-03-2018 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CO689_RS11115 fe2294e928387336d7b4d4a82c0d4cec 266 ProSitePatterns PS00923 Aspartate and glutamate racemases signature 1. 69 77 - T 28-03-2018 IPR018187 Asp/Glu racemase, active site 1 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CO689_RS11115 fe2294e928387336d7b4d4a82c0d4cec 266 Hamap MF_00258 Glutamate racemase [murI]. 3 256 38.162 T 28-03-2018 IPR004391 Glutamate racemase GO:0008881|GO:0009252 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CO689_RS11115 fe2294e928387336d7b4d4a82c0d4cec 266 TIGRFAM TIGR00067 glut_race: glutamate racemase 5 254 1.4E-77 T 28-03-2018 IPR004391 Glutamate racemase GO:0008881|GO:0009252 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CO689_RS11115 fe2294e928387336d7b4d4a82c0d4cec 266 Gene3D G3DSA:3.40.50.1860 1 114 4.6E-29 T 28-03-2018 CO689_RS11115 fe2294e928387336d7b4d4a82c0d4cec 266 Pfam PF01177 Asp/Glu/Hydantoin racemase 5 215 1.5E-34 T 28-03-2018 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CO689_RS04385 9c2ca9815255bf4d7138960aa42ad170 255 SUPERFAMILY SSF53474 7 247 5.45E-33 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CO689_RS04385 9c2ca9815255bf4d7138960aa42ad170 255 Gene3D G3DSA:3.40.50.1820 4 250 2.4E-30 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CO689_RS04385 9c2ca9815255bf4d7138960aa42ad170 255 Pfam PF12146 Serine aminopeptidase, S33 24 129 5.6E-24 T 28-03-2018 IPR022742 Serine aminopeptidase, S33 CO689_RS04385 9c2ca9815255bf4d7138960aa42ad170 255 Pfam PF12146 Serine aminopeptidase, S33 165 228 6.6E-10 T 28-03-2018 IPR022742 Serine aminopeptidase, S33 CO689_RS05070 37427a2cd75b4074659abaecc861ec0c 116 SUPERFAMILY SSF57783 4 38 2.72E-14 T 28-03-2018 CO689_RS05070 37427a2cd75b4074659abaecc861ec0c 116 TIGRFAM TIGR00686 phnA: putative alkylphosphonate utilization operon protein PhnA 5 114 7.7E-41 T 28-03-2018 IPR004624 PhnA protein CO689_RS05070 37427a2cd75b4074659abaecc861ec0c 116 Gene3D G3DSA:2.20.25.10 3 41 9.7E-18 T 28-03-2018 CO689_RS05070 37427a2cd75b4074659abaecc861ec0c 116 Gene3D G3DSA:2.30.30.40 45 114 1.5E-32 T 28-03-2018 CO689_RS05070 37427a2cd75b4074659abaecc861ec0c 116 SUPERFAMILY SSF82057 41 115 5.49E-26 T 28-03-2018 CO689_RS05070 37427a2cd75b4074659abaecc861ec0c 116 Pfam PF03831 PhnA domain 46 115 5.5E-32 T 28-03-2018 IPR013988 PhnA protein, C-terminal CO689_RS05070 37427a2cd75b4074659abaecc861ec0c 116 Pfam PF08274 PhnA Zinc-Ribbon 4 33 3.8E-16 T 28-03-2018 IPR013987 PhnA protein, N-terminal CO689_RS08695 d58f1b0f08c411054fe7375f0a4a0838 398 SUPERFAMILY SSF103473 11 393 3.66E-48 T 28-03-2018 IPR020846 Major facilitator superfamily domain CO689_RS08695 d58f1b0f08c411054fe7375f0a4a0838 398 Pfam PF07690 Major Facilitator Superfamily 17 205 3.4E-20 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CO689_RS08695 d58f1b0f08c411054fe7375f0a4a0838 398 Pfam PF07690 Major Facilitator Superfamily 223 393 2.0E-16 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CO689_RS08695 d58f1b0f08c411054fe7375f0a4a0838 398 Gene3D G3DSA:1.20.1250.20 4 211 1.7E-21 T 28-03-2018 CO689_RS08695 d58f1b0f08c411054fe7375f0a4a0838 398 Gene3D G3DSA:1.20.1250.20 212 397 1.1E-22 T 28-03-2018 CO689_RS03595 f725d93cf8a8dd36329cc9c43bd24321 451 TIGRFAM TIGR00712 glpT: glycerol-3-phosphate transporter 2 446 5.9E-207 T 28-03-2018 IPR005267 Glycerol-3-phosphate transporter GO:0015169|GO:0015794|GO:0016021 CO689_RS03595 f725d93cf8a8dd36329cc9c43bd24321 451 Pfam PF07690 Major Facilitator Superfamily 34 406 2.8E-46 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CO689_RS03595 f725d93cf8a8dd36329cc9c43bd24321 451 Gene3D G3DSA:1.20.1250.20 18 226 5.9E-30 T 28-03-2018 CO689_RS03595 f725d93cf8a8dd36329cc9c43bd24321 451 Gene3D G3DSA:1.20.1250.20 248 450 1.4E-29 T 28-03-2018 CO689_RS03595 f725d93cf8a8dd36329cc9c43bd24321 451 ProSitePatterns PS00942 glpT family of transporters signature. 153 169 - T 28-03-2018 IPR021159 Glycerate/sugar phosphate transporter, conserved site GO:0005215|GO:0006810|GO:0016021 Reactome: R-HSA-70153 CO689_RS03595 f725d93cf8a8dd36329cc9c43bd24321 451 PIRSF PIRSF002808 6 451 3.7E-158 T 28-03-2018 IPR000849 Sugar phosphate transporter GO:0005215|GO:0006810|GO:0016021 CO689_RS03595 f725d93cf8a8dd36329cc9c43bd24321 451 SUPERFAMILY SSF103473 16 444 2.35E-77 T 28-03-2018 IPR020846 Major facilitator superfamily domain CO689_RS03595 f725d93cf8a8dd36329cc9c43bd24321 451 TIGRFAM TIGR00881 2A0104: phosphoglycerate transporter family protein 35 425 3.6E-146 T 28-03-2018 CO689_RS03645 b3113fd584b6ed1f8491e09bb6e22b60 293 Gene3D G3DSA:3.40.190.10 175 259 1.3E-19 T 28-03-2018 CO689_RS03645 b3113fd584b6ed1f8491e09bb6e22b60 293 SUPERFAMILY SSF46785 2 85 5.69E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS03645 b3113fd584b6ed1f8491e09bb6e22b60 293 Gene3D G3DSA:3.40.190.10 89 174 2.4E-5 T 28-03-2018 CO689_RS03645 b3113fd584b6ed1f8491e09bb6e22b60 293 Pfam PF03466 LysR substrate binding domain 91 287 7.7E-31 T 28-03-2018 IPR005119 LysR, substrate-binding CO689_RS03645 b3113fd584b6ed1f8491e09bb6e22b60 293 Gene3D G3DSA:1.10.10.10 1 86 5.1E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS03645 b3113fd584b6ed1f8491e09bb6e22b60 293 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 3.2E-8 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CO689_RS03645 b3113fd584b6ed1f8491e09bb6e22b60 293 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 3.2E-8 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CO689_RS03645 b3113fd584b6ed1f8491e09bb6e22b60 293 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 3.2E-8 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CO689_RS03645 b3113fd584b6ed1f8491e09bb6e22b60 293 SUPERFAMILY SSF53850 92 290 1.55E-27 T 28-03-2018 CO689_RS03645 b3113fd584b6ed1f8491e09bb6e22b60 293 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 61 6.3E-17 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CO689_RS00515 e20dbcd332308d40d58bf4ee833f8ea6 552 SUPERFAMILY SSF51011 480 551 1.61E-13 T 28-03-2018 CO689_RS00515 e20dbcd332308d40d58bf4ee833f8ea6 552 Gene3D G3DSA:3.20.20.80 344 480 1.6E-20 T 28-03-2018 CO689_RS00515 e20dbcd332308d40d58bf4ee833f8ea6 552 PRINTS PR00110 Alpha-amylase signature 198 209 1.3E-5 T 28-03-2018 IPR006046 Alpha amylase GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+3.2.1.1|Reactome: R-HSA-189085 CO689_RS00515 e20dbcd332308d40d58bf4ee833f8ea6 552 PRINTS PR00110 Alpha-amylase signature 96 107 1.3E-5 T 28-03-2018 IPR006046 Alpha amylase GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+3.2.1.1|Reactome: R-HSA-189085 CO689_RS00515 e20dbcd332308d40d58bf4ee833f8ea6 552 PRINTS PR00110 Alpha-amylase signature 320 332 1.3E-5 T 28-03-2018 IPR006046 Alpha amylase GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+3.2.1.1|Reactome: R-HSA-189085 CO689_RS00515 e20dbcd332308d40d58bf4ee833f8ea6 552 SMART SM00642 17 419 3.3E-152 T 28-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CO689_RS00515 e20dbcd332308d40d58bf4ee833f8ea6 552 Pfam PF00128 Alpha amylase, catalytic domain 32 376 4.5E-115 T 28-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CO689_RS00515 e20dbcd332308d40d58bf4ee833f8ea6 552 Gene3D G3DSA:3.20.20.470 175 343 6.7E-38 T 28-03-2018 CO689_RS00515 e20dbcd332308d40d58bf4ee833f8ea6 552 Pfam PF16657 Maltogenic Amylase, C-terminal domain 480 526 5.6E-7 T 28-03-2018 IPR032091 Maltogenic Amylase, C-terminal CO689_RS00515 e20dbcd332308d40d58bf4ee833f8ea6 552 Gene3D G3DSA:3.90.400.10 109 174 5.3E-30 T 28-03-2018 CO689_RS00515 e20dbcd332308d40d58bf4ee833f8ea6 552 Gene3D G3DSA:3.20.20.470 2 99 3.3E-38 T 28-03-2018 CO689_RS00515 e20dbcd332308d40d58bf4ee833f8ea6 552 Gene3D G3DSA:2.60.40.1180 481 551 7.6E-13 T 28-03-2018 CO689_RS00515 e20dbcd332308d40d58bf4ee833f8ea6 552 SUPERFAMILY SSF51445 7 475 1.48E-150 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CO689_RS12575 cc93a57448055a7e8511cf571229dcf6 362 Pfam PF04101 Glycosyltransferase family 28 C-terminal domain 189 345 6.1E-26 T 28-03-2018 IPR007235 Glycosyl transferase, family 28, C-terminal GO:0016758 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193 CO689_RS12575 cc93a57448055a7e8511cf571229dcf6 362 SUPERFAMILY SSF53756 3 340 5.03E-85 T 28-03-2018 CO689_RS12575 cc93a57448055a7e8511cf571229dcf6 362 Hamap MF_00033 UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [murG]. 4 358 26.991 T 28-03-2018 IPR006009 N-acetylglucosaminyltransferase, MurG GO:0009252|GO:0050511 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 CO689_RS12575 cc93a57448055a7e8511cf571229dcf6 362 Gene3D G3DSA:3.40.50.2000 184 343 3.8E-24 T 28-03-2018 CO689_RS12575 cc93a57448055a7e8511cf571229dcf6 362 Pfam PF03033 Glycosyltransferase family 28 N-terminal domain 4 144 7.7E-37 T 28-03-2018 IPR004276 Glycosyltransferase family 28, N-terminal domain GO:0005975|GO:0016758|GO:0030259 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 CO689_RS12575 cc93a57448055a7e8511cf571229dcf6 362 Gene3D G3DSA:3.40.50.2000 2 183 3.2E-30 T 28-03-2018 CO689_RS02190 556970d90c977835436899475b03f822 157 Gene3D G3DSA:3.30.70.260 1 88 4.9E-13 T 28-03-2018 CO689_RS02190 556970d90c977835436899475b03f822 157 SUPERFAMILY SSF55021 1 79 3.44E-11 T 28-03-2018 CO689_RS02190 556970d90c977835436899475b03f822 157 Gene3D G3DSA:3.30.70.1150 89 157 1.5E-9 T 28-03-2018 CO689_RS02190 556970d90c977835436899475b03f822 157 Pfam PF10369 Small subunit of acetolactate synthase 86 156 4.3E-9 T 28-03-2018 IPR019455 Acetolactate synthase, small subunit, C-terminal KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 CO689_RS02190 556970d90c977835436899475b03f822 157 SUPERFAMILY SSF55021 77 156 3.5E-8 T 28-03-2018 CO689_RS02190 556970d90c977835436899475b03f822 157 TIGRFAM TIGR00119 acolac_sm: acetolactate synthase, small subunit 3 156 5.5E-23 T 28-03-2018 IPR004789 Acetolactate synthase, small subunit GO:0003984|GO:0009082 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 CO689_RS02190 556970d90c977835436899475b03f822 157 ProDom PD002844 SMALL SUBUNIT ACETOLACTATE SYNTHASE SYNTHASE TRANSFERASE ACID BIOSYNTHESIS III LYASE 1 77 4.0E-22 T 28-03-2018 CO689_RS02490 08d15314739c0391f0d1f5d76ff7d87c 209 TIGRFAM TIGR01091 upp: uracil phosphoribosyltransferase 3 209 2.4E-91 T 28-03-2018 IPR005765 Uracil phosphoribosyl transferase GO:0004845|GO:0006223 KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 CO689_RS02490 08d15314739c0391f0d1f5d76ff7d87c 209 Hamap MF_01218_B Uracil phosphoribosyltransferase [upp]. 3 209 48.116 T 28-03-2018 IPR034332 Uracil phosphoribosyltransferase, bacterial-type KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 CO689_RS02490 08d15314739c0391f0d1f5d76ff7d87c 209 Pfam PF14681 Uracil phosphoribosyltransferase 6 208 2.3E-75 T 28-03-2018 CO689_RS02490 08d15314739c0391f0d1f5d76ff7d87c 209 Gene3D G3DSA:3.40.50.2020 2 207 1.4E-66 T 28-03-2018 CO689_RS02490 08d15314739c0391f0d1f5d76ff7d87c 209 SUPERFAMILY SSF53271 4 207 2.49E-73 T 28-03-2018 IPR029057 Phosphoribosyltransferase-like CO689_RS12145 2264f0d315888624f20055bf9ef8530b 490 Gene3D G3DSA:2.60.120.560 359 488 2.9E-22 T 28-03-2018 CO689_RS12145 2264f0d315888624f20055bf9ef8530b 490 Pfam PF08244 Glycosyl hydrolases family 32 C terminal 340 482 1.1E-19 T 28-03-2018 IPR013189 Glycosyl hydrolase family 32, C-terminal CO689_RS12145 2264f0d315888624f20055bf9ef8530b 490 Pfam PF00251 Glycosyl hydrolases family 32 N-terminal domain 37 334 4.5E-96 T 28-03-2018 IPR013148 Glycosyl hydrolase family 32, N-terminal CO689_RS12145 2264f0d315888624f20055bf9ef8530b 490 Gene3D G3DSA:2.115.10.20 42 358 3.3E-89 T 28-03-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain CO689_RS12145 2264f0d315888624f20055bf9ef8530b 490 SUPERFAMILY SSF75005 28 334 1.16E-101 T 28-03-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain CO689_RS12145 2264f0d315888624f20055bf9ef8530b 490 SUPERFAMILY SSF49899 340 487 8.7E-23 T 28-03-2018 IPR013320 Concanavalin A-like lectin/glucanase domain CO689_RS12145 2264f0d315888624f20055bf9ef8530b 490 TIGRFAM TIGR01322 scrB_fam: sucrose-6-phosphate hydrolase 21 462 4.0E-167 T 28-03-2018 IPR006232 Sucrose-6-phosphate hydrolase GO:0004564|GO:0005737|GO:0005975 KEGG: 00052+3.2.1.26|KEGG: 00500+3.2.1.26 CO689_RS12145 2264f0d315888624f20055bf9ef8530b 490 ProSitePatterns PS00609 Glycosyl hydrolases family 32 active site. 37 50 - T 28-03-2018 IPR018053 Glycoside hydrolase, family 32, active site GO:0004553|GO:0005975 KEGG: 00052+3.2.1.26|KEGG: 00500+3.2.1.26 CO689_RS12145 2264f0d315888624f20055bf9ef8530b 490 SMART SM00640 37 452 2.0E-126 T 28-03-2018 IPR001362 Glycoside hydrolase, family 32 GO:0004553|GO:0005975 CO689_RS10870 976bd5a1cacf2bc3798bb79201a4425d 438 Gene3D G3DSA:3.90.1170.30 46 134 3.1E-4 T 28-03-2018 CO689_RS10870 976bd5a1cacf2bc3798bb79201a4425d 438 Gene3D G3DSA:3.90.1170.30 2 45 1.2E-12 T 28-03-2018 CO689_RS10870 976bd5a1cacf2bc3798bb79201a4425d 438 Pfam PF00364 Biotin-requiring enzyme 4 76 3.7E-24 T 28-03-2018 IPR000089 Biotin/lipoyl attachment CO689_RS10870 976bd5a1cacf2bc3798bb79201a4425d 438 SUPERFAMILY SSF52777 197 436 1.38E-86 T 28-03-2018 CO689_RS10870 976bd5a1cacf2bc3798bb79201a4425d 438 Pfam PF02817 e3 binding domain 134 169 9.5E-17 T 28-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CO689_RS10870 976bd5a1cacf2bc3798bb79201a4425d 438 SUPERFAMILY SSF47005 128 173 1.44E-13 T 28-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CO689_RS10870 976bd5a1cacf2bc3798bb79201a4425d 438 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 27 56 - T 28-03-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 CO689_RS10870 976bd5a1cacf2bc3798bb79201a4425d 438 SUPERFAMILY SSF51230 3 92 7.98E-26 T 28-03-2018 IPR011053 Single hybrid motif CO689_RS10870 976bd5a1cacf2bc3798bb79201a4425d 438 Gene3D G3DSA:3.30.559.10 189 436 7.8E-89 T 28-03-2018 CO689_RS10870 976bd5a1cacf2bc3798bb79201a4425d 438 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 208 436 1.0E-87 T 28-03-2018 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CO689_RS10870 976bd5a1cacf2bc3798bb79201a4425d 438 Gene3D G3DSA:4.10.320.10 135 181 9.1E-21 T 28-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CO689_RS01235 f5add8f0e808491639cda9b7f4993bcf 653 SUPERFAMILY SSF81660 365 477 2.75E-21 T 28-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 CO689_RS01235 f5add8f0e808491639cda9b7f4993bcf 653 Gene3D G3DSA:3.40.1110.10 361 467 6.2E-23 T 28-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 CO689_RS01235 f5add8f0e808491639cda9b7f4993bcf 653 SUPERFAMILY SSF81653 148 244 4.84E-24 T 28-03-2018 IPR008250 P-type ATPase, A domain Reactome: R-HSA-936837 CO689_RS01235 f5add8f0e808491639cda9b7f4993bcf 653 SUPERFAMILY SSF81665 100 147 4.71E-12 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CO689_RS01235 f5add8f0e808491639cda9b7f4993bcf 653 SUPERFAMILY SSF81665 245 336 4.71E-12 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CO689_RS01235 f5add8f0e808491639cda9b7f4993bcf 653 SUPERFAMILY SSF56784 439 647 1.8E-50 T 28-03-2018 IPR023214 HAD-like domain CO689_RS01235 f5add8f0e808491639cda9b7f4993bcf 653 SUPERFAMILY SSF56784 343 362 1.8E-50 T 28-03-2018 IPR023214 HAD-like domain CO689_RS01235 f5add8f0e808491639cda9b7f4993bcf 653 Gene3D G3DSA:3.40.50.1000 468 607 8.9E-40 T 28-03-2018 IPR023214 HAD-like domain CO689_RS01235 f5add8f0e808491639cda9b7f4993bcf 653 Pfam PF00702 haloacid dehalogenase-like hydrolase 340 556 5.0E-37 T 28-03-2018 CO689_RS01235 f5add8f0e808491639cda9b7f4993bcf 653 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 57 651 3.8E-185 T 28-03-2018 CO689_RS01235 f5add8f0e808491639cda9b7f4993bcf 653 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 75 649 6.0E-179 T 28-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 CO689_RS01235 f5add8f0e808491639cda9b7f4993bcf 653 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 346 352 - T 28-03-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 CO689_RS01235 f5add8f0e808491639cda9b7f4993bcf 653 PRINTS PR00943 Copper-transporting ATPase signature 519 536 2.5E-8 T 28-03-2018 CO689_RS01235 f5add8f0e808491639cda9b7f4993bcf 653 PRINTS PR00943 Copper-transporting ATPase signature 327 342 2.5E-8 T 28-03-2018 CO689_RS01235 f5add8f0e808491639cda9b7f4993bcf 653 PRINTS PR00943 Copper-transporting ATPase signature 615 629 2.5E-8 T 28-03-2018 CO689_RS01235 f5add8f0e808491639cda9b7f4993bcf 653 PRINTS PR00943 Copper-transporting ATPase signature 133 151 2.5E-8 T 28-03-2018 CO689_RS01235 f5add8f0e808491639cda9b7f4993bcf 653 PRINTS PR00943 Copper-transporting ATPase signature 267 281 2.5E-8 T 28-03-2018 CO689_RS01235 f5add8f0e808491639cda9b7f4993bcf 653 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 344 358 2.3E-25 T 28-03-2018 CO689_RS01235 f5add8f0e808491639cda9b7f4993bcf 653 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 542 561 2.3E-25 T 28-03-2018 CO689_RS01235 f5add8f0e808491639cda9b7f4993bcf 653 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 194 208 2.3E-25 T 28-03-2018 CO689_RS01235 f5add8f0e808491639cda9b7f4993bcf 653 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 467 478 2.3E-25 T 28-03-2018 CO689_RS01235 f5add8f0e808491639cda9b7f4993bcf 653 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 489 499 2.3E-25 T 28-03-2018 CO689_RS01235 f5add8f0e808491639cda9b7f4993bcf 653 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 565 577 2.3E-25 T 28-03-2018 CO689_RS01235 f5add8f0e808491639cda9b7f4993bcf 653 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 116 628 7.1E-89 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CO689_RS01235 f5add8f0e808491639cda9b7f4993bcf 653 Gene3D G3DSA:1.20.1110.10 107 360 1.1E-30 T 28-03-2018 CO689_RS01235 f5add8f0e808491639cda9b7f4993bcf 653 Pfam PF00122 E1-E2 ATPase 145 322 4.7E-50 T 28-03-2018 CO689_RS06370 3cf5d19a654a9f85ecf02a33adc5a6d3 182 Gene3D G3DSA:1.10.10.60 7 46 1.4E-10 T 28-03-2018 CO689_RS06370 3cf5d19a654a9f85ecf02a33adc5a6d3 182 SUPERFAMILY SSF46689 3 68 9.93E-14 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CO689_RS06370 3cf5d19a654a9f85ecf02a33adc5a6d3 182 ProSitePatterns PS01081 TetR-type HTH domain signature. 24 55 - T 28-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site CO689_RS06370 3cf5d19a654a9f85ecf02a33adc5a6d3 182 Gene3D G3DSA:1.10.10.60 47 80 7.6E-8 T 28-03-2018 CO689_RS06370 3cf5d19a654a9f85ecf02a33adc5a6d3 182 Pfam PF00440 Bacterial regulatory proteins, tetR family 19 58 9.8E-5 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CO689_RS07970 b638feecadfb13692f019cb2abc58cb7 484 Gene3D G3DSA:3.40.50.620 129 246 4.0E-28 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CO689_RS07970 b638feecadfb13692f019cb2abc58cb7 484 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 11 22 - T 28-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 CO689_RS07970 b638feecadfb13692f019cb2abc58cb7 484 SUPERFAMILY SSF48163 298 484 9.55E-49 T 28-03-2018 IPR008925 Aminoacyl-tRNA synthetase, class I, anticodon-binding GO:0000049 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 CO689_RS07970 b638feecadfb13692f019cb2abc58cb7 484 Gene3D G3DSA:1.10.1160.10 247 333 1.6E-30 T 28-03-2018 IPR020061 Glutamyl/glutaminyl-tRNA synthetase, class Ib, alpha-bundle domain GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0006418 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188 CO689_RS07970 b638feecadfb13692f019cb2abc58cb7 484 TIGRFAM TIGR00464 gltX_bact: glutamate--tRNA ligase 5 482 3.2E-185 T 28-03-2018 IPR004527 Glutamate-tRNA ligase, bacterial/mitochondrial GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 CO689_RS07970 b638feecadfb13692f019cb2abc58cb7 484 Gene3D G3DSA:1.10.10.350 386 484 9.4E-30 T 28-03-2018 IPR020751 Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 2 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 CO689_RS07970 b638feecadfb13692f019cb2abc58cb7 484 Hamap MF_00022 Glutamate--tRNA ligase [gltX]. 4 484 33.702 T 28-03-2018 IPR004527 Glutamate-tRNA ligase, bacterial/mitochondrial GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 CO689_RS07970 b638feecadfb13692f019cb2abc58cb7 484 Gene3D G3DSA:3.40.50.620 5 128 5.0E-34 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CO689_RS07970 b638feecadfb13692f019cb2abc58cb7 484 Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain 5 323 5.0E-120 T 28-03-2018 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain GO:0005524|GO:0016876|GO:0043039 CO689_RS07970 b638feecadfb13692f019cb2abc58cb7 484 SUPERFAMILY SSF52374 5 316 1.56E-109 T 28-03-2018 CO689_RS07970 b638feecadfb13692f019cb2abc58cb7 484 Gene3D G3DSA:1.10.8.70 335 382 1.4E-4 T 28-03-2018 IPR020752 Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 1 GO:0000049 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188 CO689_RS07970 b638feecadfb13692f019cb2abc58cb7 484 PRINTS PR00987 Glutamyl-tRNA synthetase signature 194 204 3.8E-26 T 28-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 CO689_RS07970 b638feecadfb13692f019cb2abc58cb7 484 PRINTS PR00987 Glutamyl-tRNA synthetase signature 37 50 3.8E-26 T 28-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 CO689_RS07970 b638feecadfb13692f019cb2abc58cb7 484 PRINTS PR00987 Glutamyl-tRNA synthetase signature 210 218 3.8E-26 T 28-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 CO689_RS07970 b638feecadfb13692f019cb2abc58cb7 484 PRINTS PR00987 Glutamyl-tRNA synthetase signature 8 20 3.8E-26 T 28-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 CO689_RS07970 b638feecadfb13692f019cb2abc58cb7 484 PRINTS PR00987 Glutamyl-tRNA synthetase signature 22 33 3.8E-26 T 28-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 CO689_RS11545 be25350491e8ece881f5335ff6535cf2 1189 Gene3D G3DSA:3.40.50.300 1 175 4.1E-39 T 28-03-2018 CO689_RS11545 be25350491e8ece881f5335ff6535cf2 1189 Gene3D G3DSA:1.20.5.340 264 371 0.017 T 28-03-2018 CO689_RS11545 be25350491e8ece881f5335ff6535cf2 1189 Gene3D G3DSA:1.20.5.170 372 455 0.0013 T 28-03-2018 CO689_RS11545 be25350491e8ece881f5335ff6535cf2 1189 SUPERFAMILY SSF75553 485 687 2.75E-56 T 28-03-2018 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 CO689_RS11545 be25350491e8ece881f5335ff6535cf2 1189 SMART SM00968 520 639 8.6E-43 T 28-03-2018 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 CO689_RS11545 be25350491e8ece881f5335ff6535cf2 1189 Gene3D G3DSA:1.20.120.330 666 825 5.9E-5 T 28-03-2018 CO689_RS11545 be25350491e8ece881f5335ff6535cf2 1189 Pfam PF06470 SMC proteins Flexible Hinge Domain 520 639 1.4E-31 T 28-03-2018 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 CO689_RS11545 be25350491e8ece881f5335ff6535cf2 1189 SUPERFAMILY SSF52540 979 1176 5.45E-51 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CO689_RS11545 be25350491e8ece881f5335ff6535cf2 1189 SUPERFAMILY SSF52540 3 208 5.45E-51 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CO689_RS11545 be25350491e8ece881f5335ff6535cf2 1189 Gene3D G3DSA:1.10.287.510 176 263 0.37 T 28-03-2018 CO689_RS11545 be25350491e8ece881f5335ff6535cf2 1189 Gene3D G3DSA:1.20.1480.30 456 546 0.056 T 28-03-2018 CO689_RS11545 be25350491e8ece881f5335ff6535cf2 1189 TIGRFAM TIGR02168 SMC_prok_B: chromosome segregation protein SMC 3 1177 0.0 T 28-03-2018 IPR011890 Structural maintenance of chromosomes protein, prokaryotic GO:0007062|GO:0030261 CO689_RS11545 be25350491e8ece881f5335ff6535cf2 1189 Gene3D G3DSA:3.40.50.300 855 1182 2.2E-33 T 28-03-2018 CO689_RS11545 be25350491e8ece881f5335ff6535cf2 1189 Pfam PF02463 RecF/RecN/SMC N terminal domain 3 1170 2.0E-60 T 28-03-2018 IPR003395 RecF/RecN/SMC, N-terminal CO689_RS11545 be25350491e8ece881f5335ff6535cf2 1189 Hamap MF_01894 Chromosome partition protein Smc [smc]. 2 1179 23.227 T 28-03-2018 IPR011890 Structural maintenance of chromosomes protein, prokaryotic GO:0007062|GO:0030261 CO689_RS11545 be25350491e8ece881f5335ff6535cf2 1189 PIRSF PIRSF005719 1 1183 0.0 T 28-03-2018 IPR024704 Structural maintenance of chromosomes protein CO689_RS08030 ae36c7d81030453f61ebd39b9a98e77f 166 Pfam PF00466 Ribosomal protein L10 6 101 1.3E-30 T 28-03-2018 IPR001790 Ribosomal protein L10P GO:0005622|GO:0042254 CO689_RS08030 ae36c7d81030453f61ebd39b9a98e77f 166 SUPERFAMILY SSF160369 5 160 6.54E-54 T 28-03-2018 CO689_RS08030 ae36c7d81030453f61ebd39b9a98e77f 166 ProSitePatterns PS01109 Ribosomal protein L10 signature. 8 42 - T 28-03-2018 IPR002363 Ribosomal protein L10, eubacterial, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CO689_RS08030 ae36c7d81030453f61ebd39b9a98e77f 166 Hamap MF_00362 50S ribosomal protein L10 [rplJ]. 3 161 28.531 T 28-03-2018 IPR022973 Ribosomal protein L10 CO689_RS06655 4515f8d0777255d02944e9c7a9ab5c6c 573 Gene3D G3DSA:3.40.190.100 415 523 5.3E-35 T 28-03-2018 CO689_RS06655 4515f8d0777255d02944e9c7a9ab5c6c 573 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 112 278 2.5E-19 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CO689_RS06655 4515f8d0777255d02944e9c7a9ab5c6c 573 Gene3D G3DSA:1.10.3720.10 38 286 2.6E-33 T 28-03-2018 CO689_RS06655 4515f8d0777255d02944e9c7a9ab5c6c 573 SUPERFAMILY SSF53850 317 571 8.55E-77 T 28-03-2018 CO689_RS06655 4515f8d0777255d02944e9c7a9ab5c6c 573 Pfam PF04069 Substrate binding domain of ABC-type glycine betaine transport system 320 561 4.4E-60 T 28-03-2018 IPR007210 ABC-type glycine betaine transport system, substrate-binding domain GO:0005215|GO:0006810 CO689_RS06655 4515f8d0777255d02944e9c7a9ab5c6c 573 SUPERFAMILY SSF161098 88 273 4.45E-36 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CO689_RS06655 4515f8d0777255d02944e9c7a9ab5c6c 573 Gene3D G3DSA:3.40.190.10 312 414 1.8E-14 T 28-03-2018 CO689_RS06570 3de90d8d37b79cefe89da70c14d6a35a 651 Gene3D G3DSA:1.20.5.420 59 112 2.3E-4 T 28-03-2018 CO689_RS06570 3de90d8d37b79cefe89da70c14d6a35a 651 Pfam PF00746 LPXTG cell wall anchor motif 614 647 6.5E-4 T 28-03-2018 IPR019948 Gram-positive LPXTG cell wall anchor CO689_RS06570 3de90d8d37b79cefe89da70c14d6a35a 651 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 614 647 0.0028 T 28-03-2018 CO689_RS03660 3cd23edac9ec45924fbc8ef18393f6f3 227 Gene3D G3DSA:3.40.50.1360 4 139 4.6E-40 T 28-03-2018 CO689_RS03660 3cd23edac9ec45924fbc8ef18393f6f3 227 Pfam PF06026 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) 51 220 2.5E-60 T 28-03-2018 IPR004788 Ribose 5-phosphate isomerase, type A GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 CO689_RS03660 3cd23edac9ec45924fbc8ef18393f6f3 227 Gene3D G3DSA:3.30.70.260 140 204 1.7E-17 T 28-03-2018 CO689_RS03660 3cd23edac9ec45924fbc8ef18393f6f3 227 Hamap MF_00170 Ribose-5-phosphate isomerase A [rpiA]. 3 224 29.318 T 28-03-2018 IPR020672 Ribose-5-phosphate isomerase, type A, subgroup GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 CO689_RS03660 3cd23edac9ec45924fbc8ef18393f6f3 227 TIGRFAM TIGR00021 rpiA: ribose 5-phosphate isomerase A 7 221 2.0E-74 T 28-03-2018 IPR004788 Ribose 5-phosphate isomerase, type A GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 CO689_RS03660 3cd23edac9ec45924fbc8ef18393f6f3 227 SUPERFAMILY SSF100950 6 149 2.93E-41 T 28-03-2018 CO689_RS03660 3cd23edac9ec45924fbc8ef18393f6f3 227 SUPERFAMILY SSF75445 131 207 1.15E-17 T 28-03-2018 CO689_RS13735 953a63b533001f69e6fcf725ac0f28c3 441 SUPERFAMILY SSF54534 88 243 5.11E-35 T 28-03-2018 CO689_RS13735 953a63b533001f69e6fcf725ac0f28c3 441 Pfam PF05697 Bacterial trigger factor protein (TF) 1 144 6.5E-47 T 28-03-2018 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 CO689_RS13735 953a63b533001f69e6fcf725ac0f28c3 441 Hamap MF_00303 Trigger factor [tig]. 1 427 23.807 T 28-03-2018 IPR005215 Trigger factor GO:0015031 CO689_RS13735 953a63b533001f69e6fcf725ac0f28c3 441 Pfam PF05698 Bacterial trigger factor protein (TF) C-terminus 265 422 3.0E-43 T 28-03-2018 IPR008880 Trigger factor, C-terminal GO:0006457|GO:0015031 CO689_RS13735 953a63b533001f69e6fcf725ac0f28c3 441 PIRSF PIRSF003095 1 441 1.3E-132 T 28-03-2018 IPR005215 Trigger factor GO:0015031 CO689_RS13735 953a63b533001f69e6fcf725ac0f28c3 441 SUPERFAMILY SSF109998 250 434 4.05E-39 T 28-03-2018 IPR027304 Trigger factor/SurA domain CO689_RS13735 953a63b533001f69e6fcf725ac0f28c3 441 Gene3D G3DSA:1.10.3120.10 213 399 2.5E-50 T 28-03-2018 IPR008880 Trigger factor, C-terminal GO:0006457|GO:0015031 CO689_RS13735 953a63b533001f69e6fcf725ac0f28c3 441 TIGRFAM TIGR00115 tig: trigger factor 12 421 3.3E-137 T 28-03-2018 IPR005215 Trigger factor GO:0015031 CO689_RS13735 953a63b533001f69e6fcf725ac0f28c3 441 SUPERFAMILY SSF102735 1 130 9.02E-42 T 28-03-2018 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 CO689_RS13735 953a63b533001f69e6fcf725ac0f28c3 441 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 160 239 6.8E-15 T 28-03-2018 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain CO689_RS13735 953a63b533001f69e6fcf725ac0f28c3 441 Gene3D G3DSA:3.30.70.1050 1 119 9.6E-41 T 28-03-2018 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 CO689_RS01085 487655933424ef073f35e4c2063e985c 320 SUPERFAMILY SSF102114 4 306 3.14E-57 T 28-03-2018 CO689_RS01085 487655933424ef073f35e4c2063e985c 320 Pfam PF04055 Radical SAM superfamily 50 211 1.7E-15 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CO689_RS01085 487655933424ef073f35e4c2063e985c 320 SMART SM00729 30 257 7.6E-44 T 28-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 CO689_RS01085 487655933424ef073f35e4c2063e985c 320 TIGRFAM TIGR01212 TIGR01212: radical SAM protein, TIGR01212 family 13 312 2.2E-133 T 28-03-2018 IPR005911 Protein YhcC-like GO:0051536 CO689_RS01085 487655933424ef073f35e4c2063e985c 320 Gene3D G3DSA:3.20.20.70 9 299 8.7E-33 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CO689_RS01085 487655933424ef073f35e4c2063e985c 320 Pfam PF16199 Radical_SAM C-terminal domain 218 301 2.1E-25 T 28-03-2018 IPR032432 Radical SAM, C-terminal extension Reactome: R-HSA-3214847 CO689_RS03345 4dae77345308b1380e66802af9aa371b 388 PRINTS PR00473 Galactokinase signature 90 101 6.9E-27 T 28-03-2018 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 CO689_RS03345 4dae77345308b1380e66802af9aa371b 388 PRINTS PR00473 Galactokinase signature 268 282 6.9E-27 T 28-03-2018 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 CO689_RS03345 4dae77345308b1380e66802af9aa371b 388 PRINTS PR00473 Galactokinase signature 111 129 6.9E-27 T 28-03-2018 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 CO689_RS03345 4dae77345308b1380e66802af9aa371b 388 PRINTS PR00473 Galactokinase signature 25 43 6.9E-27 T 28-03-2018 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 CO689_RS03345 4dae77345308b1380e66802af9aa371b 388 PRINTS PR00959 Mevalonate kinase family signature 23 47 8.0E-40 T 28-03-2018 CO689_RS03345 4dae77345308b1380e66802af9aa371b 388 PRINTS PR00959 Mevalonate kinase family signature 118 140 8.0E-40 T 28-03-2018 CO689_RS03345 4dae77345308b1380e66802af9aa371b 388 PRINTS PR00959 Mevalonate kinase family signature 161 180 8.0E-40 T 28-03-2018 CO689_RS03345 4dae77345308b1380e66802af9aa371b 388 PRINTS PR00959 Mevalonate kinase family signature 332 349 8.0E-40 T 28-03-2018 CO689_RS03345 4dae77345308b1380e66802af9aa371b 388 SUPERFAMILY SSF55060 204 384 2.88E-53 T 28-03-2018 IPR013750 GHMP kinase, C-terminal domain CO689_RS03345 4dae77345308b1380e66802af9aa371b 388 Pfam PF00288 GHMP kinases N terminal domain 113 180 3.7E-10 T 28-03-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 CO689_RS03345 4dae77345308b1380e66802af9aa371b 388 PIRSF PIRSF000530 1 388 7.8E-125 T 28-03-2018 IPR006206 Mevalonate/galactokinase GO:0005524|GO:0005737|GO:0008152|GO:0016301|GO:0016773 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 CO689_RS03345 4dae77345308b1380e66802af9aa371b 388 SUPERFAMILY SSF54211 3 201 7.51E-61 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CO689_RS03345 4dae77345308b1380e66802af9aa371b 388 ProSitePatterns PS00106 Galactokinase signature. 25 36 - T 28-03-2018 IPR019741 Galactokinase, conserved site KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 CO689_RS03345 4dae77345308b1380e66802af9aa371b 388 Pfam PF10509 Galactokinase galactose-binding signature 8 55 3.4E-22 T 28-03-2018 IPR019539 Galactokinase galactose-binding domain GO:0005534 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 CO689_RS03345 4dae77345308b1380e66802af9aa371b 388 Pfam PF08544 GHMP kinases C terminal 285 364 7.0E-12 T 28-03-2018 IPR013750 GHMP kinase, C-terminal domain CO689_RS03345 4dae77345308b1380e66802af9aa371b 388 Hamap MF_00246 Galactokinase [galK]. 23 385 49.414 T 28-03-2018 IPR022963 Galactokinase, bacterial GO:0004335|GO:0006012 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 CO689_RS03345 4dae77345308b1380e66802af9aa371b 388 Gene3D G3DSA:3.30.70.890 208 385 9.0E-50 T 28-03-2018 IPR013750 GHMP kinase, C-terminal domain CO689_RS03345 4dae77345308b1380e66802af9aa371b 388 Gene3D G3DSA:3.30.230.10 1 207 2.9E-55 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CO689_RS03345 4dae77345308b1380e66802af9aa371b 388 TIGRFAM TIGR00131 gal_kin: galactokinase 4 385 3.0E-116 T 28-03-2018 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 CO689_RS13305 aac731a1abfb4c5a613f382db95de327 196 Pfam PF01025 GrpE 34 196 6.2E-52 T 28-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 CO689_RS13305 aac731a1abfb4c5a613f382db95de327 196 Gene3D G3DSA:3.90.20.20 2 139 1.0E-24 T 28-03-2018 IPR013805 GrpE nucleotide exchange factor, coiled-coil Reactome: R-HSA-1268020 CO689_RS13305 aac731a1abfb4c5a613f382db95de327 196 ProSitePatterns PS01071 grpE protein signature. 151 194 - T 28-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 CO689_RS13305 aac731a1abfb4c5a613f382db95de327 196 SUPERFAMILY SSF58014 45 140 1.05E-26 T 28-03-2018 CO689_RS13305 aac731a1abfb4c5a613f382db95de327 196 Gene3D G3DSA:2.30.22.10 140 196 3.6E-21 T 28-03-2018 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 Reactome: R-HSA-1268020 CO689_RS13305 aac731a1abfb4c5a613f382db95de327 196 Hamap MF_01151 Protein GrpE [grpE]. 10 196 20.996 T 28-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 CO689_RS13305 aac731a1abfb4c5a613f382db95de327 196 SUPERFAMILY SSF51064 141 196 5.62E-18 T 28-03-2018 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 Reactome: R-HSA-1268020 CO689_RS13305 aac731a1abfb4c5a613f382db95de327 196 PRINTS PR00773 GrpE protein signature 175 194 3.3E-30 T 28-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 CO689_RS13305 aac731a1abfb4c5a613f382db95de327 196 PRINTS PR00773 GrpE protein signature 94 109 3.3E-30 T 28-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 CO689_RS13305 aac731a1abfb4c5a613f382db95de327 196 PRINTS PR00773 GrpE protein signature 148 163 3.3E-30 T 28-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 CO689_RS13305 aac731a1abfb4c5a613f382db95de327 196 PRINTS PR00773 GrpE protein signature 66 82 3.3E-30 T 28-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 CO689_RS07955 e07b7dc62247dc9d024910fb22fac161 821 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 205 334 6.3E-14 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CO689_RS07955 e07b7dc62247dc9d024910fb22fac161 821 Gene3D G3DSA:1.10.8.60 715 820 8.3E-26 T 28-03-2018 CO689_RS07955 e07b7dc62247dc9d024910fb22fac161 821 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 93 143 2.4E-14 T 28-03-2018 IPR004176 Clp, N-terminal GO:0019538 CO689_RS07955 e07b7dc62247dc9d024910fb22fac161 821 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 17 69 9.7E-18 T 28-03-2018 IPR004176 Clp, N-terminal GO:0019538 CO689_RS07955 e07b7dc62247dc9d024910fb22fac161 821 Pfam PF02151 UvrB/uvrC motif 417 452 7.3E-6 T 28-03-2018 IPR001943 UVR domain GO:0005515 CO689_RS07955 e07b7dc62247dc9d024910fb22fac161 821 SUPERFAMILY SSF52540 161 466 1.64E-77 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CO689_RS07955 e07b7dc62247dc9d024910fb22fac161 821 Gene3D G3DSA:1.10.1780.10 1 77 1.5E-21 T 28-03-2018 IPR004176 Clp, N-terminal GO:0019538 CO689_RS07955 e07b7dc62247dc9d024910fb22fac161 821 SUPERFAMILY SSF81923 5 152 9.16E-31 T 28-03-2018 IPR004176 Clp, N-terminal GO:0019538 CO689_RS07955 e07b7dc62247dc9d024910fb22fac161 821 Gene3D G3DSA:3.40.50.300 192 342 9.8E-21 T 28-03-2018 CO689_RS07955 e07b7dc62247dc9d024910fb22fac161 821 SUPERFAMILY SSF52540 486 799 1.48E-80 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CO689_RS07955 e07b7dc62247dc9d024910fb22fac161 821 Gene3D G3DSA:3.40.50.300 492 714 2.3E-53 T 28-03-2018 CO689_RS07955 e07b7dc62247dc9d024910fb22fac161 821 SMART SM00382 200 340 2.5E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain CO689_RS07955 e07b7dc62247dc9d024910fb22fac161 821 SMART SM00382 537 716 1.2E-9 T 28-03-2018 IPR003593 AAA+ ATPase domain CO689_RS07955 e07b7dc62247dc9d024910fb22fac161 821 Gene3D G3DSA:1.10.8.60 344 487 2.1E-44 T 28-03-2018 CO689_RS07955 e07b7dc62247dc9d024910fb22fac161 821 Gene3D G3DSA:1.10.1780.10 78 191 2.7E-24 T 28-03-2018 IPR004176 Clp, N-terminal GO:0019538 CO689_RS07955 e07b7dc62247dc9d024910fb22fac161 821 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 541 559 3.4E-42 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 CO689_RS07955 e07b7dc62247dc9d024910fb22fac161 821 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 615 633 3.4E-42 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 CO689_RS07955 e07b7dc62247dc9d024910fb22fac161 821 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 586 604 3.4E-42 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 CO689_RS07955 e07b7dc62247dc9d024910fb22fac161 821 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 648 662 3.4E-42 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 CO689_RS07955 e07b7dc62247dc9d024910fb22fac161 821 Pfam PF07724 AAA domain (Cdc48 subfamily) 536 709 1.2E-54 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CO689_RS07955 e07b7dc62247dc9d024910fb22fac161 821 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 295 307 - T 28-03-2018 IPR018368 ClpA/B, conserved site 1 GO:0005524 CO689_RS07955 e07b7dc62247dc9d024910fb22fac161 821 SMART SM01086 715 804 5.7E-35 T 28-03-2018 IPR019489 Clp ATPase, C-terminal CO689_RS07955 e07b7dc62247dc9d024910fb22fac161 821 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 715 794 1.9E-26 T 28-03-2018 IPR019489 Clp ATPase, C-terminal CO689_RS07955 e07b7dc62247dc9d024910fb22fac161 821 ProSitePatterns PS00871 Chaperonins clpA/B signature 2. 571 589 - T 28-03-2018 IPR028299 ClpA/B, conserved site 2 CO689_RS10885 6f89fbfba7a7c30849c4463fca305a56 179 Pfam PF01381 Helix-turn-helix 7 60 5.1E-16 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CO689_RS10885 6f89fbfba7a7c30849c4463fca305a56 179 SUPERFAMILY SSF51182 54 176 5.4E-27 T 28-03-2018 IPR011051 RmlC-like cupin domain CO689_RS10885 6f89fbfba7a7c30849c4463fca305a56 179 SUPERFAMILY SSF47413 1 66 1.66E-19 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CO689_RS10885 6f89fbfba7a7c30849c4463fca305a56 179 Gene3D G3DSA:2.60.120.10 72 179 8.7E-16 T 28-03-2018 IPR014710 RmlC-like jelly roll fold CO689_RS10885 6f89fbfba7a7c30849c4463fca305a56 179 Pfam PF07883 Cupin domain 120 173 7.4E-13 T 28-03-2018 IPR013096 Cupin 2, conserved barrel CO689_RS10885 6f89fbfba7a7c30849c4463fca305a56 179 SMART SM00530 6 61 3.4E-17 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CO689_RS10885 6f89fbfba7a7c30849c4463fca305a56 179 Gene3D G3DSA:1.10.260.40 1 71 4.1E-21 T 28-03-2018 CO689_RS09385 99d63495bb9f02bbdc0c372a9b3dd4f3 204 Pfam PF01613 Flavin reductase like domain 24 166 5.0E-21 T 28-03-2018 IPR002563 Flavin reductase like domain GO:0010181 CO689_RS09385 99d63495bb9f02bbdc0c372a9b3dd4f3 204 Gene3D G3DSA:2.30.110.10 6 200 4.5E-46 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CO689_RS09385 99d63495bb9f02bbdc0c372a9b3dd4f3 204 SUPERFAMILY SSF50475 3 197 1.72E-44 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CO689_RS09385 99d63495bb9f02bbdc0c372a9b3dd4f3 204 SMART SM00903 21 176 1.5E-22 T 28-03-2018 IPR002563 Flavin reductase like domain GO:0010181 CO689_RS03865 824173372a70110afb0cb19a231a1557 311 Gene3D G3DSA:3.30.460.20 1 129 1.5E-16 T 28-03-2018 CO689_RS03865 824173372a70110afb0cb19a231a1557 311 Gene3D G3DSA:1.20.58.340 244 311 1.5E-13 T 28-03-2018 CO689_RS03865 824173372a70110afb0cb19a231a1557 311 SUPERFAMILY SSF144083 246 308 2.35E-12 T 28-03-2018 CO689_RS03865 824173372a70110afb0cb19a231a1557 311 SUPERFAMILY SSF143865 11 245 4.71E-41 T 28-03-2018 CO689_RS03865 824173372a70110afb0cb19a231a1557 311 Gene3D G3DSA:1.20.58.340 130 243 1.6E-9 T 28-03-2018 CO689_RS03865 824173372a70110afb0cb19a231a1557 311 Pfam PF01544 CorA-like Mg2+ transporter protein 20 307 3.4E-57 T 28-03-2018 IPR002523 Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB GO:0016020|GO:0030001|GO:0046873|GO:0055085 CO689_RS00455 45786b71c93cc54433bf3e0728257331 1437 Pfam PF00746 LPXTG cell wall anchor motif 1395 1435 1.6E-9 T 28-03-2018 IPR019948 Gram-positive LPXTG cell wall anchor CO689_RS00455 45786b71c93cc54433bf3e0728257331 1437 Pfam PF08428 Rib/alpha-like repeat 617 686 9.0E-6 T 28-03-2018 CO689_RS00455 45786b71c93cc54433bf3e0728257331 1437 Pfam PF08428 Rib/alpha-like repeat 703 772 4.8E-5 T 28-03-2018 CO689_RS00455 45786b71c93cc54433bf3e0728257331 1437 Pfam PF08428 Rib/alpha-like repeat 1133 1202 9.0E-6 T 28-03-2018 CO689_RS00455 45786b71c93cc54433bf3e0728257331 1437 Pfam PF08428 Rib/alpha-like repeat 961 1030 9.0E-6 T 28-03-2018 CO689_RS00455 45786b71c93cc54433bf3e0728257331 1437 Pfam PF08428 Rib/alpha-like repeat 789 858 4.2E-5 T 28-03-2018 CO689_RS00455 45786b71c93cc54433bf3e0728257331 1437 Pfam PF08428 Rib/alpha-like repeat 1305 1373 1.1E-5 T 28-03-2018 CO689_RS00455 45786b71c93cc54433bf3e0728257331 1437 Pfam PF08428 Rib/alpha-like repeat 1047 1116 4.8E-5 T 28-03-2018 CO689_RS00455 45786b71c93cc54433bf3e0728257331 1437 Pfam PF08428 Rib/alpha-like repeat 534 600 1.2E-5 T 28-03-2018 CO689_RS00455 45786b71c93cc54433bf3e0728257331 1437 Pfam PF08428 Rib/alpha-like repeat 875 944 9.0E-6 T 28-03-2018 CO689_RS00455 45786b71c93cc54433bf3e0728257331 1437 Pfam PF08428 Rib/alpha-like repeat 1219 1288 4.8E-5 T 28-03-2018 CO689_RS00455 45786b71c93cc54433bf3e0728257331 1437 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 1399 1434 6.0E-6 T 28-03-2018 CO689_RS08365 fe318343437e4db01e6bf544ae155827 274 SUPERFAMILY SSF53474 4 258 4.9E-45 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CO689_RS08365 fe318343437e4db01e6bf544ae155827 274 Gene3D G3DSA:3.40.50.1820 2 261 4.5E-35 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CO689_RS08365 fe318343437e4db01e6bf544ae155827 274 Pfam PF00561 alpha/beta hydrolase fold 22 238 5.5E-19 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CO689_RS08365 fe318343437e4db01e6bf544ae155827 274 PRINTS PR00111 Alpha/beta hydrolase fold signature 46 61 1.5E-6 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CO689_RS08365 fe318343437e4db01e6bf544ae155827 274 PRINTS PR00111 Alpha/beta hydrolase fold signature 89 102 1.5E-6 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CO689_RS08365 fe318343437e4db01e6bf544ae155827 274 PRINTS PR00111 Alpha/beta hydrolase fold signature 203 217 1.5E-6 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CO689_RS08365 fe318343437e4db01e6bf544ae155827 274 PRINTS PR00111 Alpha/beta hydrolase fold signature 103 116 1.5E-6 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CO689_RS03410 b21e4603c542a2a87214127c7ca93b8c 229 PIRSF PIRSF009467 3 229 1.5E-78 T 28-03-2018 IPR002639 Urease accessory protein UreF GO:0006807|GO:0016151 CO689_RS03410 b21e4603c542a2a87214127c7ca93b8c 229 Pfam PF01730 UreF 37 186 6.4E-33 T 28-03-2018 IPR002639 Urease accessory protein UreF GO:0006807|GO:0016151 CO689_RS03410 b21e4603c542a2a87214127c7ca93b8c 229 Hamap MF_01385 Urease accessory protein UreF [ureF]. 5 229 27.546 T 28-03-2018 IPR002639 Urease accessory protein UreF GO:0006807|GO:0016151 CO689_RS03095 6eab60fa0a4c8859e6c9549db4ea7e63 105 TIGRFAM TIGR01079 rplX_bact: ribosomal protein uL24 1 101 1.6E-39 T 28-03-2018 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CO689_RS03095 6eab60fa0a4c8859e6c9549db4ea7e63 105 Pfam PF17136 Ribosomal proteins 50S L24/mitochondrial 39S L24 38 101 5.1E-31 T 28-03-2018 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CO689_RS03095 6eab60fa0a4c8859e6c9549db4ea7e63 105 Gene3D G3DSA:2.30.30.30 1 91 5.2E-37 T 28-03-2018 IPR014722 Ribosomal protein L2 domain 2 CO689_RS03095 6eab60fa0a4c8859e6c9549db4ea7e63 105 SUPERFAMILY SSF50104 1 99 5.59E-38 T 28-03-2018 IPR008991 Translation protein SH3-like domain CO689_RS03095 6eab60fa0a4c8859e6c9549db4ea7e63 105 Hamap MF_01326_B 50S ribosomal protein L24 [rplX]. 1 95 22.004 T 28-03-2018 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CO689_RS03095 6eab60fa0a4c8859e6c9549db4ea7e63 105 Pfam PF00467 KOW motif 5 36 6.8E-9 T 28-03-2018 IPR005824 KOW CO689_RS03095 6eab60fa0a4c8859e6c9549db4ea7e63 105 ProSitePatterns PS01108 Ribosomal protein L24 signature. 6 23 - T 28-03-2018 IPR005825 Ribosomal protein L24/L26, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CO689_RS03095 6eab60fa0a4c8859e6c9549db4ea7e63 105 SMART SM00739 2 29 4.9E-6 T 28-03-2018 IPR005824 KOW CO689_RS10240 db8f70ad567259518e5ad1c9a244f742 261 Pfam PF13743 Thioredoxin 27 189 1.9E-43 T 28-03-2018 CO689_RS10240 db8f70ad567259518e5ad1c9a244f742 261 SUPERFAMILY SSF52833 24 197 1.58E-13 T 28-03-2018 IPR012336 Thioredoxin-like fold CO689_RS10240 db8f70ad567259518e5ad1c9a244f742 261 Gene3D G3DSA:3.40.30.10 13 203 3.3E-14 T 28-03-2018 CO689_RS06340 58743d48e9e91f43a46afa62ac4d4473 375 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 68 82 - T 28-03-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 CO689_RS06340 58743d48e9e91f43a46afa62ac4d4473 375 Pfam PF00107 Zinc-binding dehydrogenase 204 323 3.0E-29 T 28-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CO689_RS06340 58743d48e9e91f43a46afa62ac4d4473 375 SUPERFAMILY SSF50129 1 200 2.43E-61 T 28-03-2018 IPR011032 GroES-like CO689_RS06340 58743d48e9e91f43a46afa62ac4d4473 375 Gene3D G3DSA:3.40.50.720 197 317 3.6E-26 T 28-03-2018 CO689_RS06340 58743d48e9e91f43a46afa62ac4d4473 375 SMART SM00829 18 372 1.9E-6 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CO689_RS06340 58743d48e9e91f43a46afa62ac4d4473 375 SUPERFAMILY SSF51735 166 339 2.45E-47 T 28-03-2018 IPR016040 NAD(P)-binding domain CO689_RS06340 58743d48e9e91f43a46afa62ac4d4473 375 Gene3D G3DSA:3.90.180.10 1 196 3.1E-58 T 28-03-2018 CO689_RS06340 58743d48e9e91f43a46afa62ac4d4473 375 SUPERFAMILY SSF50129 323 372 3.01E-7 T 28-03-2018 IPR011032 GroES-like CO689_RS06340 58743d48e9e91f43a46afa62ac4d4473 375 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 36 162 5.6E-27 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CO689_RS11240 28fea660cfd0829c5dff0367015272ec 388 Pfam PF12327 FtsZ family, C-terminal domain 222 316 7.0E-34 T 28-03-2018 IPR024757 Cell division protein FtsZ, C-terminal CO689_RS11240 28fea660cfd0829c5dff0367015272ec 388 Pfam PF00091 Tubulin/FtsZ family, GTPase domain 14 173 1.2E-44 T 28-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 CO689_RS11240 28fea660cfd0829c5dff0367015272ec 388 Hamap MF_00909 Cell division protein FtsZ [ftsZ]. 9 347 38.891 T 28-03-2018 IPR000158 Cell division protein FtsZ GO:0005525 CO689_RS11240 28fea660cfd0829c5dff0367015272ec 388 Gene3D G3DSA:3.40.50.1440 9 214 4.1E-47 T 28-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 CO689_RS11240 28fea660cfd0829c5dff0367015272ec 388 Gene3D G3DSA:3.30.1330.20 215 324 1.7E-47 T 28-03-2018 IPR018316 Tubulin/FtsZ, 2-layer sandwich domain Reactome: R-HSA-1445148|Reactome: R-HSA-190840|Reactome: R-HSA-190861|Reactome: R-HSA-2132295|Reactome: R-HSA-2467813|Reactome: R-HSA-2500257|Reactome: R-HSA-3371497|Reactome: R-HSA-380320|Reactome: R-HSA-437239|Reactome: R-HSA-5617833|Reactome: R-HSA-5626467|Reactome: R-HSA-5663220|Reactome: R-HSA-6807878|Reactome: R-HSA-6811434|Reactome: R-HSA-6811436|Reactome: R-HSA-68877|Reactome: R-HSA-8852276|Reactome: R-HSA-8955332|Reactome: R-HSA-983189 CO689_RS11240 28fea660cfd0829c5dff0367015272ec 388 SMART SM00864 13 205 1.2E-115 T 28-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 CO689_RS11240 28fea660cfd0829c5dff0367015272ec 388 PRINTS PR00423 Cell division protein FtsZ signature 212 233 1.2E-50 T 28-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 CO689_RS11240 28fea660cfd0829c5dff0367015272ec 388 PRINTS PR00423 Cell division protein FtsZ signature 126 147 1.2E-50 T 28-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 CO689_RS11240 28fea660cfd0829c5dff0367015272ec 388 PRINTS PR00423 Cell division protein FtsZ signature 189 211 1.2E-50 T 28-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 CO689_RS11240 28fea660cfd0829c5dff0367015272ec 388 PRINTS PR00423 Cell division protein FtsZ signature 98 118 1.2E-50 T 28-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 CO689_RS11240 28fea660cfd0829c5dff0367015272ec 388 ProSitePatterns PS01135 FtsZ protein signature 2. 97 118 - T 28-03-2018 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 CO689_RS11240 28fea660cfd0829c5dff0367015272ec 388 SUPERFAMILY SSF55307 207 319 2.29E-44 T 28-03-2018 IPR008280 Tubulin/FtsZ, C-terminal Reactome: R-HSA-380320 CO689_RS11240 28fea660cfd0829c5dff0367015272ec 388 SUPERFAMILY SSF52490 13 208 1.44E-71 T 28-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 CO689_RS11240 28fea660cfd0829c5dff0367015272ec 388 TIGRFAM TIGR00065 ftsZ: cell division protein FtsZ 11 328 7.8E-137 T 28-03-2018 IPR000158 Cell division protein FtsZ GO:0005525 CO689_RS11240 28fea660cfd0829c5dff0367015272ec 388 SMART SM00865 207 324 1.8E-56 T 28-03-2018 IPR018316 Tubulin/FtsZ, 2-layer sandwich domain Reactome: R-HSA-1445148|Reactome: R-HSA-190840|Reactome: R-HSA-190861|Reactome: R-HSA-2132295|Reactome: R-HSA-2467813|Reactome: R-HSA-2500257|Reactome: R-HSA-3371497|Reactome: R-HSA-380320|Reactome: R-HSA-437239|Reactome: R-HSA-5617833|Reactome: R-HSA-5626467|Reactome: R-HSA-5663220|Reactome: R-HSA-6807878|Reactome: R-HSA-6811434|Reactome: R-HSA-6811436|Reactome: R-HSA-68877|Reactome: R-HSA-8852276|Reactome: R-HSA-8955332|Reactome: R-HSA-983189 CO689_RS11240 28fea660cfd0829c5dff0367015272ec 388 ProSitePatterns PS01134 FtsZ protein signature 1. 44 78 - T 28-03-2018 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 CO689_RS06645 d7d49080b7982999864be15f6a72c61d 201 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 37 48 1.7E-31 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CO689_RS06645 d7d49080b7982999864be15f6a72c61d 201 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 111 130 1.7E-31 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CO689_RS06645 d7d49080b7982999864be15f6a72c61d 201 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 161 181 1.7E-31 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CO689_RS06645 d7d49080b7982999864be15f6a72c61d 201 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 132 149 1.7E-31 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CO689_RS06645 d7d49080b7982999864be15f6a72c61d 201 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 85 101 1.7E-31 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CO689_RS06645 d7d49080b7982999864be15f6a72c61d 201 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 98 126 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CO689_RS06645 d7d49080b7982999864be15f6a72c61d 201 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 3 198 2.8E-53 T 28-03-2018 CO689_RS06645 d7d49080b7982999864be15f6a72c61d 201 Gene3D G3DSA:3.40.50.720 1 201 1.6E-59 T 28-03-2018 CO689_RS06645 d7d49080b7982999864be15f6a72c61d 201 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 111 130 1.8E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CO689_RS06645 d7d49080b7982999864be15f6a72c61d 201 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 91 99 1.8E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CO689_RS06645 d7d49080b7982999864be15f6a72c61d 201 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 37 48 1.8E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CO689_RS06645 d7d49080b7982999864be15f6a72c61d 201 SUPERFAMILY SSF51735 3 199 1.5E-59 T 28-03-2018 IPR016040 NAD(P)-binding domain CO689_RS04565 38ddc08563ef1837f021998e773c6129 246 Pfam PF02677 Uncharacterized BCR, COG1636 38 218 6.6E-63 T 28-03-2018 IPR003828 Probable epoxyqueuosine reductase QueH CO689_RS04660 1c618b2404a1275e02d1cacd6a021e31 243 SMART SM00796 1 203 4.0E-95 T 28-03-2018 IPR003833 Carboxyltransferase domain, subdomain C and D CO689_RS04660 1c618b2404a1275e02d1cacd6a021e31 243 TIGRFAM TIGR00370 TIGR00370: sensor histidine kinase inhibitor, KipI family 6 211 5.0E-63 T 28-03-2018 IPR010016 KipI family CO689_RS04660 1c618b2404a1275e02d1cacd6a021e31 243 SUPERFAMILY SSF160467 3 93 5.23E-15 T 28-03-2018 CO689_RS04660 1c618b2404a1275e02d1cacd6a021e31 243 SUPERFAMILY SSF50891 89 219 2.09E-48 T 28-03-2018 IPR029000 Cyclophilin-like domain CO689_RS04660 1c618b2404a1275e02d1cacd6a021e31 243 Gene3D G3DSA:3.30.1360.40 1 79 3.3E-13 T 28-03-2018 IPR024946 Arginine repressor C-terminal-like domain Reactome: R-HSA-4615885 CO689_RS04660 1c618b2404a1275e02d1cacd6a021e31 243 Gene3D G3DSA:2.40.100.10 87 221 5.6E-53 T 28-03-2018 IPR029000 Cyclophilin-like domain CO689_RS04660 1c618b2404a1275e02d1cacd6a021e31 243 Pfam PF02682 Carboxyltransferase domain, subdomain C and D 2 202 3.9E-73 T 28-03-2018 IPR003833 Carboxyltransferase domain, subdomain C and D CO689_RS07430 be0119851b2e48d13269317e42dc0c76 825 Gene3D G3DSA:3.90.780.10 442 647 3.7E-47 T 28-03-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CO689_RS07430 be0119851b2e48d13269317e42dc0c76 825 SUPERFAMILY SSF56300 155 438 3.8E-73 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CO689_RS07430 be0119851b2e48d13269317e42dc0c76 825 PRINTS PR01607 Apyrase family signature 152 170 6.4E-23 T 28-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CO689_RS07430 be0119851b2e48d13269317e42dc0c76 825 PRINTS PR01607 Apyrase family signature 315 332 6.4E-23 T 28-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CO689_RS07430 be0119851b2e48d13269317e42dc0c76 825 PRINTS PR01607 Apyrase family signature 502 525 6.4E-23 T 28-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CO689_RS07430 be0119851b2e48d13269317e42dc0c76 825 PRINTS PR01607 Apyrase family signature 348 371 6.4E-23 T 28-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CO689_RS07430 be0119851b2e48d13269317e42dc0c76 825 PRINTS PR01607 Apyrase family signature 587 606 6.4E-23 T 28-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CO689_RS07430 be0119851b2e48d13269317e42dc0c76 825 ProSitePatterns PS00786 5'-nucleotidase signature 2. 221 232 - T 28-03-2018 IPR006146 5'-Nucleotidase, conserved site GO:0000166|GO:0016788|GO:0046872 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CO689_RS07430 be0119851b2e48d13269317e42dc0c76 825 SUPERFAMILY SSF55816 446 640 4.71E-45 T 28-03-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CO689_RS07430 be0119851b2e48d13269317e42dc0c76 825 Gene3D G3DSA:3.60.21.10 147 439 2.5E-67 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CO689_RS07430 be0119851b2e48d13269317e42dc0c76 825 Pfam PF00149 Calcineurin-like phosphoesterase 155 365 8.4E-15 T 28-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 CO689_RS07430 be0119851b2e48d13269317e42dc0c76 825 Pfam PF02872 5'-nucleotidase, C-terminal domain 449 612 1.5E-38 T 28-03-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CO689_RS10430 52c86a67ec87669d1cd04d47ec6e71d8 211 SMART SM00725 17 140 4.3E-24 T 28-03-2018 IPR006635 NEAT domain CO689_RS10430 52c86a67ec87669d1cd04d47ec6e71d8 211 SUPERFAMILY SSF158911 23 134 7.06E-29 T 28-03-2018 CO689_RS10430 52c86a67ec87669d1cd04d47ec6e71d8 211 TIGRFAM TIGR03656 IsdC: heme uptake protein IsdC 17 210 2.8E-50 T 28-03-2018 IPR019909 Haem uptake protein IsdC GO:0009274|GO:0015886|GO:0030492 CO689_RS10430 52c86a67ec87669d1cd04d47ec6e71d8 211 Pfam PF05031 Iron Transport-associated domain 23 130 7.0E-22 T 28-03-2018 IPR006635 NEAT domain CO689_RS10430 52c86a67ec87669d1cd04d47ec6e71d8 211 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 181 208 0.0036 T 28-03-2018 CO689_RS07775 8bf44840891e8e3e35529e0716c32c2e 700 Hamap MF_01458 ATP-dependent zinc metalloprotease FtsH [ftsH]. 3 617 37.656 T 28-03-2018 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 Reactome: R-HSA-8949664 CO689_RS07775 8bf44840891e8e3e35529e0716c32c2e 700 ProSitePatterns PS00674 AAA-protein family signature. 304 322 - T 28-03-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 CO689_RS07775 8bf44840891e8e3e35529e0716c32c2e 700 SMART SM00382 197 336 5.1E-26 T 28-03-2018 IPR003593 AAA+ ATPase domain CO689_RS07775 8bf44840891e8e3e35529e0716c32c2e 700 SUPERFAMILY SSF52540 158 405 9.64E-75 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CO689_RS07775 8bf44840891e8e3e35529e0716c32c2e 700 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 201 333 3.5E-46 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CO689_RS07775 8bf44840891e8e3e35529e0716c32c2e 700 Pfam PF01434 Peptidase family M41 395 603 2.1E-83 T 28-03-2018 IPR000642 Peptidase M41 GO:0004222|GO:0005524|GO:0006508 Reactome: R-HSA-8949664 CO689_RS07775 8bf44840891e8e3e35529e0716c32c2e 700 SUPERFAMILY SSF140990 415 609 3.53E-69 T 28-03-2018 CO689_RS07775 8bf44840891e8e3e35529e0716c32c2e 700 Gene3D G3DSA:1.10.8.60 351 422 7.8E-24 T 28-03-2018 CO689_RS07775 8bf44840891e8e3e35529e0716c32c2e 700 TIGRFAM TIGR01241 FtsH_fam: ATP-dependent metallopeptidase HflB 112 604 2.0E-240 T 28-03-2018 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 Reactome: R-HSA-8949664 CO689_RS07775 8bf44840891e8e3e35529e0716c32c2e 700 Pfam PF06480 FtsH Extracellular 9 95 3.4E-10 T 28-03-2018 IPR011546 Peptidase M41, FtsH extracellular GO:0004222|GO:0005524|GO:0008270|GO:0016021 Reactome: R-HSA-8949664 CO689_RS07775 8bf44840891e8e3e35529e0716c32c2e 700 Gene3D G3DSA:3.40.50.300 141 350 1.3E-64 T 28-03-2018 CO689_RS08290 45552751b0b5d831949a05db17b42a91 279 Gene3D G3DSA:3.30.930.10 4 269 4.1E-37 T 28-03-2018 CO689_RS08290 45552751b0b5d831949a05db17b42a91 279 Pfam PF03099 Biotin/lipoate A/B protein ligase family 76 180 9.2E-15 T 28-03-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 CO689_RS08290 45552751b0b5d831949a05db17b42a91 279 SUPERFAMILY SSF55681 13 271 1.24E-64 T 28-03-2018 CO689_RS08290 45552751b0b5d831949a05db17b42a91 279 Hamap MF_02119 Lipoyl-[GcvH]:protein N-lipoyltransferase [lipL]. 6 275 47.502 T 28-03-2018 IPR024897 Octanoyltransferase LipL GO:0009107|GO:0009249|GO:0016415 KEGG: 00073+2.3.1.20|KEGG: 00561+2.3.1.20|MetaCyc: PWY-6987 CO689_RS00115 9655037b564cd0a11509f2e75e6c7c91 142 Gene3D G3DSA:3.30.1330.70 2 142 2.4E-18 T 28-03-2018 IPR008822 Crossover junction endodeoxyribonuclease, RusA-like GO:0000287|GO:0006281|GO:0006310 CO689_RS00115 9655037b564cd0a11509f2e75e6c7c91 142 SUPERFAMILY SSF103084 5 140 1.44E-9 T 28-03-2018 IPR008822 Crossover junction endodeoxyribonuclease, RusA-like GO:0000287|GO:0006281|GO:0006310 CO689_RS00115 9655037b564cd0a11509f2e75e6c7c91 142 Pfam PF05866 Endodeoxyribonuclease RusA 12 138 4.1E-18 T 28-03-2018 IPR008822 Crossover junction endodeoxyribonuclease, RusA-like GO:0000287|GO:0006281|GO:0006310 CO689_RS00080 9655037b564cd0a11509f2e75e6c7c91 142 Gene3D G3DSA:3.30.1330.70 2 142 2.4E-18 T 28-03-2018 IPR008822 Crossover junction endodeoxyribonuclease, RusA-like GO:0000287|GO:0006281|GO:0006310 CO689_RS00080 9655037b564cd0a11509f2e75e6c7c91 142 SUPERFAMILY SSF103084 5 140 1.44E-9 T 28-03-2018 IPR008822 Crossover junction endodeoxyribonuclease, RusA-like GO:0000287|GO:0006281|GO:0006310 CO689_RS00080 9655037b564cd0a11509f2e75e6c7c91 142 Pfam PF05866 Endodeoxyribonuclease RusA 12 138 4.1E-18 T 28-03-2018 IPR008822 Crossover junction endodeoxyribonuclease, RusA-like GO:0000287|GO:0006281|GO:0006310 CO689_RS00755 9655037b564cd0a11509f2e75e6c7c91 142 Gene3D G3DSA:3.30.1330.70 2 142 2.4E-18 T 28-03-2018 IPR008822 Crossover junction endodeoxyribonuclease, RusA-like GO:0000287|GO:0006281|GO:0006310 CO689_RS00755 9655037b564cd0a11509f2e75e6c7c91 142 SUPERFAMILY SSF103084 5 140 1.44E-9 T 28-03-2018 IPR008822 Crossover junction endodeoxyribonuclease, RusA-like GO:0000287|GO:0006281|GO:0006310 CO689_RS00755 9655037b564cd0a11509f2e75e6c7c91 142 Pfam PF05866 Endodeoxyribonuclease RusA 12 138 4.1E-18 T 28-03-2018 IPR008822 Crossover junction endodeoxyribonuclease, RusA-like GO:0000287|GO:0006281|GO:0006310 CO689_RS00725 9655037b564cd0a11509f2e75e6c7c91 142 Gene3D G3DSA:3.30.1330.70 2 142 2.4E-18 T 28-03-2018 IPR008822 Crossover junction endodeoxyribonuclease, RusA-like GO:0000287|GO:0006281|GO:0006310 CO689_RS00725 9655037b564cd0a11509f2e75e6c7c91 142 SUPERFAMILY SSF103084 5 140 1.44E-9 T 28-03-2018 IPR008822 Crossover junction endodeoxyribonuclease, RusA-like GO:0000287|GO:0006281|GO:0006310 CO689_RS00725 9655037b564cd0a11509f2e75e6c7c91 142 Pfam PF05866 Endodeoxyribonuclease RusA 12 138 4.1E-18 T 28-03-2018 IPR008822 Crossover junction endodeoxyribonuclease, RusA-like GO:0000287|GO:0006281|GO:0006310 CO689_RS12515 9d67adfe0032deed172c0cd958e03b13 306 SMART SM00046 7 132 0.0033 T 28-03-2018 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 CO689_RS12515 9d67adfe0032deed172c0cd958e03b13 306 Gene3D G3DSA:3.40.50.10330 2 141 7.9E-24 T 28-03-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, domain 1 GO:0003951|GO:0008152 CO689_RS12515 9d67adfe0032deed172c0cd958e03b13 306 Pfam PF00781 Diacylglycerol kinase catalytic domain 8 133 9.2E-26 T 28-03-2018 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 CO689_RS12515 9d67adfe0032deed172c0cd958e03b13 306 SUPERFAMILY SSF111331 5 299 1.77E-59 T 28-03-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain CO689_RS12515 9d67adfe0032deed172c0cd958e03b13 306 TIGRFAM TIGR00147 TIGR00147: lipid kinase, YegS/Rv2252/BmrU family 9 297 2.4E-50 T 28-03-2018 IPR005218 Diacylglycerol/lipid kinase CO689_RS08970 d898240e2ba03e42254583fc8b33b3bc 507 Gene3D G3DSA:1.20.1250.20 13 214 3.7E-22 T 28-03-2018 CO689_RS08970 d898240e2ba03e42254583fc8b33b3bc 507 Gene3D G3DSA:1.20.1250.20 295 504 6.4E-8 T 28-03-2018 CO689_RS08970 d898240e2ba03e42254583fc8b33b3bc 507 SUPERFAMILY SSF103473 284 501 9.42E-29 T 28-03-2018 IPR020846 Major facilitator superfamily domain CO689_RS08970 d898240e2ba03e42254583fc8b33b3bc 507 SUPERFAMILY SSF103473 16 216 9.42E-29 T 28-03-2018 IPR020846 Major facilitator superfamily domain CO689_RS08970 d898240e2ba03e42254583fc8b33b3bc 507 TIGRFAM TIGR00924 yjdL_sub1_fam: amino acid/peptide transporter (Peptide:H+ symporter) 19 503 3.5E-117 T 28-03-2018 IPR005279 Dipeptide/tripeptide permease GO:0015197|GO:0015833|GO:0016020 CO689_RS08970 d898240e2ba03e42254583fc8b33b3bc 507 Pfam PF00854 POT family 99 476 1.1E-68 T 28-03-2018 IPR000109 Proton-dependent oligopeptide transporter family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-427975 CO689_RS08970 d898240e2ba03e42254583fc8b33b3bc 507 ProSitePatterns PS01023 PTR2 family proton/oligopeptide symporters signature 2. 160 172 - T 28-03-2018 IPR018456 PTR2 family proton/oligopeptide symporter, conserved site GO:0005215|GO:0006857|GO:0016020 Reactome: R-HSA-427975 CO689_RS11250 3267a01c8cd84dd3a757005984b9efaf 224 TIGRFAM TIGR00044 TIGR00044: pyridoxal phosphate enzyme, YggS family 2 221 1.1E-47 T 28-03-2018 IPR011078 Pyridoxal phosphate homeostasis protein CO689_RS11250 3267a01c8cd84dd3a757005984b9efaf 224 Gene3D G3DSA:3.20.20.10 1 224 2.1E-53 T 28-03-2018 IPR029066 PLP-binding barrel CO689_RS11250 3267a01c8cd84dd3a757005984b9efaf 224 PIRSF PIRSF004848 1 224 2.6E-63 T 28-03-2018 IPR011078 Pyridoxal phosphate homeostasis protein CO689_RS11250 3267a01c8cd84dd3a757005984b9efaf 224 Pfam PF01168 Alanine racemase, N-terminal domain 6 221 5.1E-20 T 28-03-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CO689_RS11250 3267a01c8cd84dd3a757005984b9efaf 224 SUPERFAMILY SSF51419 1 221 8.24E-71 T 28-03-2018 IPR029066 PLP-binding barrel CO689_RS07785 41ed554629c84f16cd412beeb2f795a1 311 ProSitePatterns PS00901 Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. 35 53 - T 28-03-2018 IPR001216 Cysteine synthase/cystathionine beta-synthase, pyridoxal-phosphate attachment site GO:0006535 CO689_RS07785 41ed554629c84f16cd412beeb2f795a1 311 SUPERFAMILY SSF53686 5 306 3.01E-105 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CO689_RS07785 41ed554629c84f16cd412beeb2f795a1 311 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 11 294 2.4E-72 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CO689_RS07785 41ed554629c84f16cd412beeb2f795a1 311 Gene3D G3DSA:3.40.50.1100 43 139 2.6E-41 T 28-03-2018 CO689_RS07785 41ed554629c84f16cd412beeb2f795a1 311 Gene3D G3DSA:3.40.50.1100 140 308 2.7E-58 T 28-03-2018 CO689_RS07785 41ed554629c84f16cd412beeb2f795a1 311 TIGRFAM TIGR01139 cysK: cysteine synthase A 10 306 7.7E-139 T 28-03-2018 IPR005859 Cysteine synthase CysK GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 CO689_RS07785 41ed554629c84f16cd412beeb2f795a1 311 TIGRFAM TIGR01136 cysKM: cysteine synthase 10 306 1.1E-131 T 28-03-2018 IPR005856 Cysteine synthase GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 CO689_RS03500 fde0525492a7bb5a20736bcabf4125db 374 Pfam PF01494 FAD binding domain 2 330 1.2E-18 T 28-03-2018 IPR002938 FAD-binding domain GO:0071949 CO689_RS03500 fde0525492a7bb5a20736bcabf4125db 374 SUPERFAMILY SSF51905 256 355 6.72E-56 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CO689_RS03500 fde0525492a7bb5a20736bcabf4125db 374 SUPERFAMILY SSF51905 1 161 6.72E-56 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CO689_RS03500 fde0525492a7bb5a20736bcabf4125db 374 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 284 300 1.4E-17 T 28-03-2018 CO689_RS03500 fde0525492a7bb5a20736bcabf4125db 374 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 2 24 1.4E-17 T 28-03-2018 CO689_RS03500 fde0525492a7bb5a20736bcabf4125db 374 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 269 284 1.4E-17 T 28-03-2018 CO689_RS03500 fde0525492a7bb5a20736bcabf4125db 374 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 140 155 1.4E-17 T 28-03-2018 CO689_RS03500 fde0525492a7bb5a20736bcabf4125db 374 Gene3D G3DSA:3.50.50.60 1 336 2.5E-42 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CO689_RS10760 c411e729043cbb1361bb0dc05f079e3a 492 SUPERFAMILY SSF52335 2 190 2.22E-69 T 28-03-2018 IPR011607 Methylglyoxal synthase-like domain CO689_RS10760 c411e729043cbb1361bb0dc05f079e3a 492 Hamap MF_00139 Bifunctional purine biosynthesis protein PurH [purH]. 1 492 42.135 T 28-03-2018 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CO689_RS10760 c411e729043cbb1361bb0dc05f079e3a 492 Gene3D G3DSA:3.40.50.1380 1 190 2.2E-72 T 28-03-2018 IPR011607 Methylglyoxal synthase-like domain CO689_RS10760 c411e729043cbb1361bb0dc05f079e3a 492 Pfam PF01808 AICARFT/IMPCHase bienzyme 133 426 4.2E-110 T 28-03-2018 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CO689_RS10760 c411e729043cbb1361bb0dc05f079e3a 492 Gene3D G3DSA:3.40.140.20 197 341 3.9E-53 T 28-03-2018 IPR024051 AICAR transformylase domain KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CO689_RS10760 c411e729043cbb1361bb0dc05f079e3a 492 SUPERFAMILY SSF53927 191 492 4.61E-119 T 28-03-2018 IPR016193 Cytidine deaminase-like GO:0003824 CO689_RS10760 c411e729043cbb1361bb0dc05f079e3a 492 SMART SM00798 133 427 2.2E-179 T 28-03-2018 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CO689_RS10760 c411e729043cbb1361bb0dc05f079e3a 492 SMART SM00851 13 128 1.4E-56 T 28-03-2018 IPR011607 Methylglyoxal synthase-like domain CO689_RS10760 c411e729043cbb1361bb0dc05f079e3a 492 TIGRFAM TIGR00355 purH: phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 2 492 1.8E-196 T 28-03-2018 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CO689_RS10760 c411e729043cbb1361bb0dc05f079e3a 492 PIRSF PIRSF000414 1 492 2.2E-196 T 28-03-2018 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CO689_RS10760 c411e729043cbb1361bb0dc05f079e3a 492 Gene3D G3DSA:3.40.140.20 342 482 9.2E-47 T 28-03-2018 IPR024051 AICAR transformylase domain KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CO689_RS10760 c411e729043cbb1361bb0dc05f079e3a 492 Pfam PF02142 MGS-like domain 13 128 1.4E-29 T 28-03-2018 IPR011607 Methylglyoxal synthase-like domain CO689_RS12910 0a78f465cc66f23ec312f49ac3677f1e 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 143 162 4.5E-9 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CO689_RS12910 0a78f465cc66f23ec312f49ac3677f1e 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 5 22 4.5E-9 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CO689_RS12910 0a78f465cc66f23ec312f49ac3677f1e 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 162 179 4.5E-9 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CO689_RS12910 0a78f465cc66f23ec312f49ac3677f1e 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 72 83 4.5E-9 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CO689_RS12910 0a78f465cc66f23ec312f49ac3677f1e 250 Gene3D G3DSA:3.40.50.720 2 250 2.3E-40 T 28-03-2018 CO689_RS12910 0a78f465cc66f23ec312f49ac3677f1e 250 Pfam PF00106 short chain dehydrogenase 4 183 5.2E-24 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CO689_RS12910 0a78f465cc66f23ec312f49ac3677f1e 250 SUPERFAMILY SSF51735 3 245 6.24E-38 T 28-03-2018 IPR016040 NAD(P)-binding domain CO689_RS12910 0a78f465cc66f23ec312f49ac3677f1e 250 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 4 177 0.0022 T 28-03-2018 CO689_RS13810 ca9b5e7c11c224dd27aa97d205e3740f 572 SMART SM00387 453 565 7.5E-35 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CO689_RS13810 ca9b5e7c11c224dd27aa97d205e3740f 572 Gene3D G3DSA:3.30.450.20 224 347 2.3E-18 T 28-03-2018 CO689_RS13810 ca9b5e7c11c224dd27aa97d205e3740f 572 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 457 559 6.2E-25 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CO689_RS13810 ca9b5e7c11c224dd27aa97d205e3740f 572 Gene3D G3DSA:3.30.565.10 412 568 1.4E-42 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CO689_RS13810 ca9b5e7c11c224dd27aa97d205e3740f 572 Gene3D G3DSA:1.10.287.130 348 405 4.4E-18 T 28-03-2018 CO689_RS13810 ca9b5e7c11c224dd27aa97d205e3740f 572 Pfam PF00512 His Kinase A (phospho-acceptor) domain 343 408 5.3E-20 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CO689_RS13810 ca9b5e7c11c224dd27aa97d205e3740f 572 SMART SM00388 342 409 3.0E-24 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CO689_RS13810 ca9b5e7c11c224dd27aa97d205e3740f 572 Pfam PF00989 PAS fold 227 333 1.7E-5 T 28-03-2018 IPR013767 PAS fold GO:0006355 CO689_RS13810 ca9b5e7c11c224dd27aa97d205e3740f 572 SUPERFAMILY SSF55874 398 561 3.67E-45 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CO689_RS13810 ca9b5e7c11c224dd27aa97d205e3740f 572 SUPERFAMILY SSF47384 328 409 2.55E-20 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CO689_RS13810 ca9b5e7c11c224dd27aa97d205e3740f 572 PRINTS PR00344 Bacterial sensor protein C-terminal signature 508 518 1.2E-14 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CO689_RS13810 ca9b5e7c11c224dd27aa97d205e3740f 572 PRINTS PR00344 Bacterial sensor protein C-terminal signature 549 562 1.2E-14 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CO689_RS13810 ca9b5e7c11c224dd27aa97d205e3740f 572 PRINTS PR00344 Bacterial sensor protein C-terminal signature 525 543 1.2E-14 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CO689_RS13810 ca9b5e7c11c224dd27aa97d205e3740f 572 PRINTS PR00344 Bacterial sensor protein C-terminal signature 490 504 1.2E-14 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CO689_RS13810 ca9b5e7c11c224dd27aa97d205e3740f 572 SUPERFAMILY SSF55785 214 334 3.62E-9 T 28-03-2018 IPR000014 PAS domain CO689_RS08010 9837c2da4e4337c14cb7be5ec19308cb 68 Hamap MF_00422 Protein translocase subunit SecE [secE]. 11 66 12.776 T 28-03-2018 IPR022943 Preprotein translocase subunit SecE Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 CO689_RS08010 9837c2da4e4337c14cb7be5ec19308cb 68 ProSitePatterns PS01067 Protein secE/sec61-gamma signature. 16 44 - T 28-03-2018 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 CO689_RS08010 9837c2da4e4337c14cb7be5ec19308cb 68 TIGRFAM TIGR00964 secE_bact: preprotein translocase, SecE subunit 15 67 3.0E-22 T 28-03-2018 IPR005807 SecE subunit of protein translocation complex GO:0009306|GO:0015450|GO:0016021 CO689_RS08010 9837c2da4e4337c14cb7be5ec19308cb 68 Gene3D G3DSA:1.20.5.1030 15 64 1.2E-19 T 28-03-2018 CO689_RS08010 9837c2da4e4337c14cb7be5ec19308cb 68 Pfam PF00584 SecE/Sec61-gamma subunits of protein translocation complex 15 67 1.3E-19 T 28-03-2018 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 CO689_RS02540 7bb50d721cd883f87d3e8715014a87e5 461 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 244 251 - T 28-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 CO689_RS02540 7bb50d721cd883f87d3e8715014a87e5 461 SUPERFAMILY SSF53720 3 455 1.7E-143 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CO689_RS02540 7bb50d721cd883f87d3e8715014a87e5 461 Pfam PF00171 Aldehyde dehydrogenase family 13 455 8.6E-150 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CO689_RS02540 7bb50d721cd883f87d3e8715014a87e5 461 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 272 283 - T 28-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 CO689_RS02540 7bb50d721cd883f87d3e8715014a87e5 461 Gene3D G3DSA:3.40.605.10 1 262 6.7E-88 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CO689_RS02540 7bb50d721cd883f87d3e8715014a87e5 461 Gene3D G3DSA:3.40.309.10 263 441 5.3E-58 T 28-03-2018 CO689_RS12200 949d357f83ce6f17a6aaf051d87996e3 375 Pfam PF00149 Calcineurin-like phosphoesterase 1 214 2.2E-16 T 28-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 CO689_RS12200 949d357f83ce6f17a6aaf051d87996e3 375 Gene3D G3DSA:3.60.21.10 73 264 4.5E-27 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CO689_RS12200 949d357f83ce6f17a6aaf051d87996e3 375 Gene3D G3DSA:3.60.21.10 1 72 2.1E-15 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CO689_RS12200 949d357f83ce6f17a6aaf051d87996e3 375 SUPERFAMILY SSF56300 1 315 2.28E-54 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CO689_RS12200 949d357f83ce6f17a6aaf051d87996e3 375 Pfam PF12320 Type 5 capsule protein repressor C-terminal domain 262 349 1.0E-8 T 28-03-2018 IPR026843 Nuclease SbcCD subunit D, C-terminal domain CO689_RS12200 949d357f83ce6f17a6aaf051d87996e3 375 TIGRFAM TIGR00619 sbcd: exonuclease SbcCD, D subunit 1 241 4.1E-54 T 28-03-2018 IPR004593 Nuclease SbcCD subunit D GO:0004519|GO:0006259|GO:0008408 CO689_RS04230 2a5286ab1ffe0f61ac5c4d96a1f8ed71 511 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 3 247 6.9E-72 T 28-03-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 CO689_RS04230 2a5286ab1ffe0f61ac5c4d96a1f8ed71 511 PIRSF PIRSF000538 1 505 2.5E-144 T 28-03-2018 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 CO689_RS04230 2a5286ab1ffe0f61ac5c4d96a1f8ed71 511 SUPERFAMILY SSF53067 1 247 1.37E-71 T 28-03-2018 CO689_RS04230 2a5286ab1ffe0f61ac5c4d96a1f8ed71 511 ProSitePatterns PS00445 FGGY family of carbohydrate kinases signature 2. 364 384 - T 28-03-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 CO689_RS04230 2a5286ab1ffe0f61ac5c4d96a1f8ed71 511 ProSitePatterns PS00933 FGGY family of carbohydrate kinases signature 1. 132 144 - T 28-03-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 CO689_RS04230 2a5286ab1ffe0f61ac5c4d96a1f8ed71 511 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 257 452 5.8E-31 T 28-03-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 CO689_RS04230 2a5286ab1ffe0f61ac5c4d96a1f8ed71 511 Gene3D G3DSA:3.30.420.40 249 511 3.6E-61 T 28-03-2018 CO689_RS04230 2a5286ab1ffe0f61ac5c4d96a1f8ed71 511 TIGRFAM TIGR01314 gntK_FGGY: gluconate kinase 3 508 1.5E-268 T 28-03-2018 IPR006002 Gluconate kinase GO:0019521|GO:0046316 KEGG: 00030+2.7.1.12|MetaCyc: PWY-5530 CO689_RS04230 2a5286ab1ffe0f61ac5c4d96a1f8ed71 511 SUPERFAMILY SSF53067 251 500 1.53E-63 T 28-03-2018 CO689_RS04230 2a5286ab1ffe0f61ac5c4d96a1f8ed71 511 Gene3D G3DSA:3.30.420.40 1 248 3.4E-71 T 28-03-2018 CO689_RS13800 e7ce2bfdb1c61948afa80e16776953f0 290 Gene3D G3DSA:1.10.8.50 152 290 5.8E-41 T 28-03-2018 CO689_RS13800 e7ce2bfdb1c61948afa80e16776953f0 290 Pfam PF06831 Formamidopyrimidine-DNA glycosylase H2TH domain 151 241 6.2E-21 T 28-03-2018 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 CO689_RS13800 e7ce2bfdb1c61948afa80e16776953f0 290 SMART SM00898 2 136 8.1E-33 T 28-03-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 CO689_RS13800 e7ce2bfdb1c61948afa80e16776953f0 290 ProSitePatterns PS01242 Zinc finger FPG-type signature. 265 289 - T 28-03-2018 IPR015887 DNA glycosylase/AP lyase, zinc finger domain, DNA-binding site GO:0003677|GO:0003906|GO:0006281|GO:0008270|GO:0016799 CO689_RS13800 e7ce2bfdb1c61948afa80e16776953f0 290 SUPERFAMILY SSF81624 2 155 8.9E-28 T 28-03-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 CO689_RS13800 e7ce2bfdb1c61948afa80e16776953f0 290 TIGRFAM TIGR00577 fpg: DNA-formamidopyrimidine glycosylase 1 289 1.7E-74 T 28-03-2018 IPR020629 Formamidopyrimidine-DNA glycosylase GO:0003906|GO:0006281|GO:0008270|GO:0008534 CO689_RS13800 e7ce2bfdb1c61948afa80e16776953f0 290 Pfam PF06827 Zinc finger found in FPG and IleRS 265 290 1.6E-10 T 28-03-2018 IPR010663 Zinc finger, FPG/IleRS-type Reactome: R-HSA-379726 CO689_RS13800 e7ce2bfdb1c61948afa80e16776953f0 290 Gene3D G3DSA:3.20.190.10 2 150 1.2E-31 T 28-03-2018 CO689_RS13800 e7ce2bfdb1c61948afa80e16776953f0 290 SUPERFAMILY SSF57716 240 290 7.13E-13 T 28-03-2018 CO689_RS13800 e7ce2bfdb1c61948afa80e16776953f0 290 SUPERFAMILY SSF46946 150 241 5.1E-26 T 28-03-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 CO689_RS13800 e7ce2bfdb1c61948afa80e16776953f0 290 Pfam PF01149 Formamidopyrimidine-DNA glycosylase N-terminal domain 2 135 1.3E-27 T 28-03-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 CO689_RS13800 e7ce2bfdb1c61948afa80e16776953f0 290 SMART SM01232 150 244 1.6E-34 T 28-03-2018 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 CO689_RS02930 fdcbf1950e1b82085232719ac8c997a5 880 Gene3D G3DSA:3.20.20.60 535 873 3.3E-100 T 28-03-2018 CO689_RS02930 fdcbf1950e1b82085232719ac8c997a5 880 Gene3D G3DSA:3.30.1490.20 2 117 5.3E-32 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CO689_RS02930 fdcbf1950e1b82085232719ac8c997a5 880 Pfam PF00391 PEP-utilising enzyme, mobile domain 422 503 8.9E-27 T 28-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 CO689_RS02930 fdcbf1950e1b82085232719ac8c997a5 880 SUPERFAMILY SSF52009 389 511 1.31E-35 T 28-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 CO689_RS02930 fdcbf1950e1b82085232719ac8c997a5 880 ProSitePatterns PS00370 PEP-utilizing enzymes phosphorylation site signature. 450 461 - T 28-03-2018 IPR018274 PEP-utilising enzyme, active site GO:0016310|GO:0016772 CO689_RS02930 fdcbf1950e1b82085232719ac8c997a5 880 Gene3D G3DSA:1.10.189.10 341 389 1.8E-19 T 28-03-2018 CO689_RS02930 fdcbf1950e1b82085232719ac8c997a5 880 TIGRFAM TIGR01828 pyru_phos_dikin: pyruvate, phosphate dikinase 3 869 0.0 T 28-03-2018 IPR010121 Pyruvate, phosphate dikinase GO:0006090|GO:0050242 KEGG: 00620+2.7.9.1|KEGG: 00710+2.7.9.1|KEGG: 00720+2.7.9.1|MetaCyc: PWY-241|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117 CO689_RS02930 fdcbf1950e1b82085232719ac8c997a5 880 ProSitePatterns PS00742 PEP-utilizing enzymes signature 2. 760 778 - T 28-03-2018 IPR023151 PEP-utilising enzyme, conserved site GO:0016772 CO689_RS02930 fdcbf1950e1b82085232719ac8c997a5 880 Gene3D G3DSA:3.30.470.20 243 340 2.5E-24 T 28-03-2018 CO689_RS02930 fdcbf1950e1b82085232719ac8c997a5 880 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 17 296 2.9E-45 T 28-03-2018 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 CO689_RS02930 fdcbf1950e1b82085232719ac8c997a5 880 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 302 354 1.3E-11 T 28-03-2018 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 CO689_RS02930 fdcbf1950e1b82085232719ac8c997a5 880 PIRSF PIRSF000853 1 877 0.0 T 28-03-2018 IPR010121 Pyruvate, phosphate dikinase GO:0006090|GO:0050242 KEGG: 00620+2.7.9.1|KEGG: 00710+2.7.9.1|KEGG: 00720+2.7.9.1|MetaCyc: PWY-241|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117 CO689_RS02930 fdcbf1950e1b82085232719ac8c997a5 880 SUPERFAMILY SSF51621 515 869 9.87E-115 T 28-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CO689_RS02930 fdcbf1950e1b82085232719ac8c997a5 880 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 517 869 2.1E-79 T 28-03-2018 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 CO689_RS02930 fdcbf1950e1b82085232719ac8c997a5 880 Gene3D G3DSA:3.50.30.10 394 534 3.6E-40 T 28-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 CO689_RS02930 fdcbf1950e1b82085232719ac8c997a5 880 SUPERFAMILY SSF56059 1 378 1.01E-141 T 28-03-2018 CO689_RS02930 fdcbf1950e1b82085232719ac8c997a5 880 Gene3D G3DSA:1.20.80.30 118 197 2.7E-30 T 28-03-2018 CO689_RS11950 65fb34b54ed60d3b5ca949186433f872 165 TIGRFAM TIGR02359 thiW: energy coupling factor transporter S component ThiW 4 158 8.7E-58 T 28-03-2018 IPR012652 Energy coupling factor transporter S component ThiW CO689_RS11950 65fb34b54ed60d3b5ca949186433f872 165 Pfam PF09512 Thiamine-precursor transporter protein (ThiW) 6 153 2.9E-50 T 28-03-2018 IPR012652 Energy coupling factor transporter S component ThiW CO689_RS11950 65fb34b54ed60d3b5ca949186433f872 165 PIRSF PIRSF024534 1 164 3.4E-61 T 28-03-2018 IPR012652 Energy coupling factor transporter S component ThiW CO689_RS07995 46999cd128b899ca19a8c77b5f81c4bb 176 Pfam PF05991 YacP-like NYN domain 8 171 2.3E-45 T 28-03-2018 IPR010298 Protein of unknown function DUF901 CO689_RS06180 f907e23f9bf67d7ca6c5d345b1416859 934 SUPERFAMILY SSF52540 197 407 4.39E-33 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CO689_RS06180 f907e23f9bf67d7ca6c5d345b1416859 934 Pfam PF04851 Type III restriction enzyme, res subunit 239 401 7.7E-35 T 28-03-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 CO689_RS06180 f907e23f9bf67d7ca6c5d345b1416859 934 SMART SM00487 237 424 3.8E-14 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CO689_RS06180 f907e23f9bf67d7ca6c5d345b1416859 934 Pfam PF04313 Type I restriction enzyme R protein N terminus (HSDR_N) 3 187 1.6E-38 T 28-03-2018 IPR007409 Restriction endonuclease, type I, HsdR, N-terminal GO:0003677|GO:0004519|GO:0006304 CO689_RS06180 f907e23f9bf67d7ca6c5d345b1416859 934 TIGRFAM TIGR00348 hsdR: type I site-specific deoxyribonuclease, HsdR family 6 663 3.1E-133 T 28-03-2018 IPR004473 Restriction endonuclease, type I, HsdR GO:0003677|GO:0005524|GO:0009035|GO:0009307 CO689_RS06180 f907e23f9bf67d7ca6c5d345b1416859 934 Pfam PF12008 Type I restriction and modification enzyme - subunit R C terminal 668 930 8.2E-45 T 28-03-2018 IPR022625 Type-1 restriction enzyme R protein, C-terminal CO689_RS06180 f907e23f9bf67d7ca6c5d345b1416859 934 Gene3D G3DSA:3.40.50.300 234 416 7.4E-25 T 28-03-2018 CO689_RS03555 337783d32dc4dd5f1d2129ba27bdc71f 290 Pfam PF01418 Helix-turn-helix domain, rpiR family 3 77 2.1E-17 T 28-03-2018 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 CO689_RS03555 337783d32dc4dd5f1d2129ba27bdc71f 290 Pfam PF01380 SIS domain 126 254 9.5E-16 T 28-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 CO689_RS03555 337783d32dc4dd5f1d2129ba27bdc71f 290 SUPERFAMILY SSF53697 101 280 1.13E-26 T 28-03-2018 CO689_RS03555 337783d32dc4dd5f1d2129ba27bdc71f 290 Gene3D G3DSA:3.40.50.10490 96 287 1.5E-24 T 28-03-2018 CO689_RS03555 337783d32dc4dd5f1d2129ba27bdc71f 290 SUPERFAMILY SSF46689 1 78 3.23E-16 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CO689_RS03555 337783d32dc4dd5f1d2129ba27bdc71f 290 Gene3D G3DSA:1.10.10.10 1 95 1.4E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS07265 63b468e64a58208648c88a2f3b4c2fee 385 TIGRFAM TIGR00937 2A51: chromate efflux transporter 11 380 2.9E-104 T 28-03-2018 IPR014047 Chromate transporter, long chain CO689_RS07265 63b468e64a58208648c88a2f3b4c2fee 385 PIRSF PIRSF004810 1 385 7.8E-119 T 28-03-2018 IPR014047 Chromate transporter, long chain CO689_RS07265 63b468e64a58208648c88a2f3b4c2fee 385 Pfam PF02417 Chromate transporter 6 162 2.1E-30 T 28-03-2018 IPR003370 Chromate transporter GO:0015109|GO:0015703 CO689_RS07265 63b468e64a58208648c88a2f3b4c2fee 385 Pfam PF02417 Chromate transporter 219 381 8.7E-41 T 28-03-2018 IPR003370 Chromate transporter GO:0015109|GO:0015703 CO689_RS10265 26b1f20bd9aeb6e7f058e509fa8a73ce 269 Gene3D G3DSA:2.60.200.30 122 241 1.1E-23 T 28-03-2018 IPR017437 ATP-NAD kinase, PpnK-type, all-beta GO:0003951|GO:0008152|GO:0019674 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 CO689_RS10265 26b1f20bd9aeb6e7f058e509fa8a73ce 269 Gene3D G3DSA:3.40.50.10330 1 121 8.1E-27 T 28-03-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, domain 1 GO:0003951|GO:0008152 CO689_RS10265 26b1f20bd9aeb6e7f058e509fa8a73ce 269 Pfam PF01513 ATP-NAD kinase 35 187 5.4E-24 T 28-03-2018 IPR002504 NAD kinase GO:0003951|GO:0006741|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 CO689_RS10265 26b1f20bd9aeb6e7f058e509fa8a73ce 269 Hamap MF_00361 NAD kinase [nadK]. 1 264 23.34 T 28-03-2018 IPR002504 NAD kinase GO:0003951|GO:0006741|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 CO689_RS10265 26b1f20bd9aeb6e7f058e509fa8a73ce 269 SUPERFAMILY SSF111331 25 262 4.71E-62 T 28-03-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain CO689_RS12935 4908662fad1b3e82013638a90ae00c76 469 Gene3D G3DSA:1.20.5.320 434 467 1.7E-19 T 28-03-2018 CO689_RS12935 4908662fad1b3e82013638a90ae00c76 469 SUPERFAMILY SSF51735 3 172 9.11E-54 T 28-03-2018 IPR016040 NAD(P)-binding domain CO689_RS12935 4908662fad1b3e82013638a90ae00c76 469 Pfam PF00393 6-phosphogluconate dehydrogenase, C-terminal domain 178 465 2.2E-135 T 28-03-2018 IPR006114 6-phosphogluconate dehydrogenase, C-terminal GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 CO689_RS12935 4908662fad1b3e82013638a90ae00c76 469 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 355 377 4.9E-87 T 28-03-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 CO689_RS12935 4908662fad1b3e82013638a90ae00c76 469 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 248 275 4.9E-87 T 28-03-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 CO689_RS12935 4908662fad1b3e82013638a90ae00c76 469 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 118 143 4.9E-87 T 28-03-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 CO689_RS12935 4908662fad1b3e82013638a90ae00c76 469 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 3 26 4.9E-87 T 28-03-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 CO689_RS12935 4908662fad1b3e82013638a90ae00c76 469 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 65 94 4.9E-87 T 28-03-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 CO689_RS12935 4908662fad1b3e82013638a90ae00c76 469 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 167 195 4.9E-87 T 28-03-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 CO689_RS12935 4908662fad1b3e82013638a90ae00c76 469 SUPERFAMILY SSF48179 176 467 2.04E-130 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CO689_RS12935 4908662fad1b3e82013638a90ae00c76 469 SMART SM01350 178 466 1.7E-221 T 28-03-2018 IPR006114 6-phosphogluconate dehydrogenase, C-terminal GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 CO689_RS12935 4908662fad1b3e82013638a90ae00c76 469 Gene3D G3DSA:1.10.1040.10 180 433 1.2E-113 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CO689_RS12935 4908662fad1b3e82013638a90ae00c76 469 ProSitePatterns PS00461 6-phosphogluconate dehydrogenase signature. 252 264 - T 28-03-2018 IPR006184 6-phosphogluconate-binding site GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 CO689_RS12935 4908662fad1b3e82013638a90ae00c76 469 PIRSF PIRSF000109 1 469 1.3E-240 T 28-03-2018 IPR006113 6-phosphogluconate dehydrogenase, decarboxylating GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 CO689_RS12935 4908662fad1b3e82013638a90ae00c76 469 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 4 173 8.3E-53 T 28-03-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 CO689_RS12935 4908662fad1b3e82013638a90ae00c76 469 Gene3D G3DSA:3.40.50.720 1 179 7.5E-37 T 28-03-2018 CO689_RS12935 4908662fad1b3e82013638a90ae00c76 469 TIGRFAM TIGR00873 gnd: 6-phosphogluconate dehydrogenase (decarboxylating) 4 466 1.9E-224 T 28-03-2018 IPR006113 6-phosphogluconate dehydrogenase, decarboxylating GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 CO689_RS11225 450a97b3bafc1e85ead9b30fdf2a076c 449 Gene3D G3DSA:3.40.1190.10 101 305 1.1E-50 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CO689_RS11225 450a97b3bafc1e85ead9b30fdf2a076c 449 Gene3D G3DSA:3.40.50.720 2 100 2.0E-16 T 28-03-2018 CO689_RS11225 450a97b3bafc1e85ead9b30fdf2a076c 449 Pfam PF08245 Mur ligase middle domain 116 288 1.2E-34 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CO689_RS11225 450a97b3bafc1e85ead9b30fdf2a076c 449 Hamap MF_00639 UDP-N-acetylmuramoylalanine--D-glutamate ligase [murD]. 10 445 34.226 T 28-03-2018 IPR005762 UDP-N-acetylmuramoylalanine-D-glutamate ligase GO:0005524|GO:0005737|GO:0008360|GO:0008764|GO:0051301 KEGG: 00471+6.3.2.9|KEGG: 00550+6.3.2.9|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CO689_RS11225 450a97b3bafc1e85ead9b30fdf2a076c 449 SUPERFAMILY SSF53244 307 443 2.52E-38 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CO689_RS11225 450a97b3bafc1e85ead9b30fdf2a076c 449 Gene3D G3DSA:3.90.190.20 312 444 7.8E-33 T 28-03-2018 CO689_RS11225 450a97b3bafc1e85ead9b30fdf2a076c 449 SUPERFAMILY SSF51984 10 99 3.4E-16 T 28-03-2018 CO689_RS11225 450a97b3bafc1e85ead9b30fdf2a076c 449 Pfam PF02875 Mur ligase family, glutamate ligase domain 308 372 6.7E-8 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CO689_RS11225 450a97b3bafc1e85ead9b30fdf2a076c 449 SUPERFAMILY SSF53623 102 305 1.96E-51 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CO689_RS11225 450a97b3bafc1e85ead9b30fdf2a076c 449 TIGRFAM TIGR01087 murD: UDP-N-acetylmuramoylalanine--D-glutamate ligase 11 443 2.5E-119 T 28-03-2018 IPR005762 UDP-N-acetylmuramoylalanine-D-glutamate ligase GO:0005524|GO:0005737|GO:0008360|GO:0008764|GO:0051301 KEGG: 00471+6.3.2.9|KEGG: 00550+6.3.2.9|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CO689_RS06225 a0750b981bffa6865228d561bd2f489b 1006 SMART SM00900 399 473 8.9E-17 T 28-03-2018 IPR007329 FMN-binding GO:0010181|GO:0016020 CO689_RS06225 a0750b981bffa6865228d561bd2f489b 1006 SUPERFAMILY SSF56425 793 944 1.79E-37 T 28-03-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 CO689_RS06225 a0750b981bffa6865228d561bd2f489b 1006 SUPERFAMILY SSF51395 2 341 2.69E-95 T 28-03-2018 CO689_RS06225 a0750b981bffa6865228d561bd2f489b 1006 SUPERFAMILY SSF51905 947 1004 1.42E-52 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CO689_RS06225 a0750b981bffa6865228d561bd2f489b 1006 SUPERFAMILY SSF51905 607 808 1.42E-52 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CO689_RS06225 a0750b981bffa6865228d561bd2f489b 1006 SUPERFAMILY SSF51905 483 558 1.42E-52 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CO689_RS06225 a0750b981bffa6865228d561bd2f489b 1006 Gene3D G3DSA:3.20.20.70 1 374 1.6E-100 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CO689_RS06225 a0750b981bffa6865228d561bd2f489b 1006 Gene3D G3DSA:3.90.700.10 817 946 4.0E-40 T 28-03-2018 CO689_RS06225 a0750b981bffa6865228d561bd2f489b 1006 TIGRFAM TIGR01813 flavo_cyto_c: flavocytochrome c 631 1000 3.1E-94 T 28-03-2018 IPR010960 Flavocytochrome c GO:0000104|GO:0055114 CO689_RS06225 a0750b981bffa6865228d561bd2f489b 1006 Pfam PF04205 FMN-binding domain 399 470 2.3E-9 T 28-03-2018 IPR007329 FMN-binding GO:0010181|GO:0016020 CO689_RS06225 a0750b981bffa6865228d561bd2f489b 1006 Pfam PF00890 FAD binding domain 500 988 4.0E-68 T 28-03-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 CO689_RS06225 a0750b981bffa6865228d561bd2f489b 1006 Gene3D G3DSA:3.50.50.60 496 816 4.4E-22 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CO689_RS06225 a0750b981bffa6865228d561bd2f489b 1006 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 5 338 3.3E-75 T 28-03-2018 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 CO689_RS06550 156ae145e3ff4032e6462f0b68b8a35c 336 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 57 71 - T 28-03-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 CO689_RS06550 156ae145e3ff4032e6462f0b68b8a35c 336 Gene3D G3DSA:3.90.180.10 1 162 9.2E-48 T 28-03-2018 CO689_RS06550 156ae145e3ff4032e6462f0b68b8a35c 336 SUPERFAMILY SSF50129 1 158 1.08E-43 T 28-03-2018 IPR011032 GroES-like CO689_RS06550 156ae145e3ff4032e6462f0b68b8a35c 336 SUPERFAMILY SSF51735 134 301 3.94E-36 T 28-03-2018 IPR016040 NAD(P)-binding domain CO689_RS06550 156ae145e3ff4032e6462f0b68b8a35c 336 Gene3D G3DSA:3.40.50.720 163 282 1.2E-21 T 28-03-2018 CO689_RS06550 156ae145e3ff4032e6462f0b68b8a35c 336 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 25 131 8.3E-27 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CO689_RS06550 156ae145e3ff4032e6462f0b68b8a35c 336 Pfam PF00107 Zinc-binding dehydrogenase 172 296 2.8E-27 T 28-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CO689_RS06550 156ae145e3ff4032e6462f0b68b8a35c 336 SMART SM00829 7 332 5.4E-6 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CO689_RS11480 11b60e4e3fad0602f45debebd40fdee9 216 Pfam PF04265 Thiamin pyrophosphokinase, vitamin B1 binding domain 147 202 5.2E-13 T 28-03-2018 IPR007373 Thiamin pyrophosphokinase, vitamin B1-binding domain GO:0009229|GO:0030975 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 CO689_RS11480 11b60e4e3fad0602f45debebd40fdee9 216 SMART SM00983 140 205 1.2E-14 T 28-03-2018 IPR007373 Thiamin pyrophosphokinase, vitamin B1-binding domain GO:0009229|GO:0030975 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 CO689_RS11480 11b60e4e3fad0602f45debebd40fdee9 216 SUPERFAMILY SSF63862 131 210 6.93E-12 T 28-03-2018 IPR007373 Thiamin pyrophosphokinase, vitamin B1-binding domain GO:0009229|GO:0030975 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 CO689_RS11480 11b60e4e3fad0602f45debebd40fdee9 216 TIGRFAM TIGR01378 thi_PPkinase: thiamine pyrophosphokinase 4 207 6.8E-51 T 28-03-2018 IPR006282 Thiamin pyrophosphokinase GO:0004788|GO:0006772 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 CO689_RS11480 11b60e4e3fad0602f45debebd40fdee9 216 Pfam PF04263 Thiamin pyrophosphokinase, catalytic domain 28 115 1.1E-13 T 28-03-2018 IPR007371 Thiamin pyrophosphokinase, catalytic domain GO:0004788|GO:0005524|GO:0009229 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 CO689_RS11480 11b60e4e3fad0602f45debebd40fdee9 216 Gene3D G3DSA:3.40.50.10240 2 114 4.9E-16 T 28-03-2018 IPR007371 Thiamin pyrophosphokinase, catalytic domain GO:0004788|GO:0005524|GO:0009229 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 CO689_RS11480 11b60e4e3fad0602f45debebd40fdee9 216 Gene3D G3DSA:2.60.120.320 115 215 8.0E-20 T 28-03-2018 IPR007373 Thiamin pyrophosphokinase, vitamin B1-binding domain GO:0009229|GO:0030975 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 CO689_RS11480 11b60e4e3fad0602f45debebd40fdee9 216 SUPERFAMILY SSF63999 3 128 9.68E-26 T 28-03-2018 IPR007371 Thiamin pyrophosphokinase, catalytic domain GO:0004788|GO:0005524|GO:0009229 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 CO689_RS12580 fd08c02e7292453c5de47861cfd1b20a 168 Pfam PF00583 Acetyltransferase (GNAT) family 29 141 1.4E-13 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CO689_RS12580 fd08c02e7292453c5de47861cfd1b20a 168 SUPERFAMILY SSF55729 1 152 1.77E-22 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CO689_RS12580 fd08c02e7292453c5de47861cfd1b20a 168 Gene3D G3DSA:3.40.630.30 1 168 4.8E-26 T 28-03-2018 CO689_RS07045 5e18869aa26955f53d1ef1c34f0212ba 624 SUPERFAMILY SSF51905 4 64 5.61E-46 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CO689_RS07045 5e18869aa26955f53d1ef1c34f0212ba 624 SUPERFAMILY SSF51905 95 258 5.61E-46 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CO689_RS07045 5e18869aa26955f53d1ef1c34f0212ba 624 TIGRFAM TIGR00136 gidA: tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA 5 617 3.6E-287 T 28-03-2018 IPR004416 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG GO:0002098 Reactome: R-HSA-6787450 CO689_RS07045 5e18869aa26955f53d1ef1c34f0212ba 624 Gene3D G3DSA:3.50.50.60 3 262 6.0E-68 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CO689_RS07045 5e18869aa26955f53d1ef1c34f0212ba 624 Pfam PF01134 Glucose inhibited division protein A 6 394 2.5E-167 T 28-03-2018 IPR002218 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG-related GO:0008033|GO:0050660 Reactome: R-HSA-6787450 CO689_RS07045 5e18869aa26955f53d1ef1c34f0212ba 624 Hamap MF_00129 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG [mnmG]. 3 620 41.82 T 28-03-2018 IPR004416 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG GO:0002098 Reactome: R-HSA-6787450 CO689_RS07045 5e18869aa26955f53d1ef1c34f0212ba 624 SMART SM01228 542 613 1.5E-40 T 28-03-2018 CO689_RS07045 5e18869aa26955f53d1ef1c34f0212ba 624 ProSitePatterns PS01281 Glucose inhibited division protein A family signature 2. 365 388 - T 28-03-2018 IPR020595 MnmG-related, conserved site Reactome: R-HSA-6787450 CO689_RS07045 5e18869aa26955f53d1ef1c34f0212ba 624 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 149 158 2.1E-5 T 28-03-2018 CO689_RS07045 5e18869aa26955f53d1ef1c34f0212ba 624 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 6 28 2.1E-5 T 28-03-2018 CO689_RS07045 5e18869aa26955f53d1ef1c34f0212ba 624 Pfam PF13932 GidA associated domain 399 612 6.1E-79 T 28-03-2018 IPR026904 GidA associated domain 3 Reactome: R-HSA-6787450 CO689_RS02455 bf35eecad64554b880023490c05ab6cb 503 Gene3D G3DSA:3.40.50.300 83 364 1.0E-117 T 28-03-2018 CO689_RS02455 bf35eecad64554b880023490c05ab6cb 503 Hamap MF_01346 ATP synthase subunit alpha [atpA]. 1 499 50.892 T 28-03-2018 IPR005294 ATP synthase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CO689_RS02455 bf35eecad64554b880023490c05ab6cb 503 PIRSF PIRSF039088 1 501 3.2E-247 T 28-03-2018 IPR005294 ATP synthase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CO689_RS02455 bf35eecad64554b880023490c05ab6cb 503 TIGRFAM TIGR00962 atpA: ATP synthase F1, alpha subunit 3 499 8.8E-253 T 28-03-2018 IPR005294 ATP synthase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CO689_RS02455 bf35eecad64554b880023490c05ab6cb 503 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 149 364 8.1E-73 T 28-03-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CO689_RS02455 bf35eecad64554b880023490c05ab6cb 503 Gene3D G3DSA:2.40.30.20 3 82 3.7E-37 T 28-03-2018 IPR023366 ATP synthase subunit alpha-like domain KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CO689_RS02455 bf35eecad64554b880023490c05ab6cb 503 SUPERFAMILY SSF52540 95 370 4.94E-97 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CO689_RS02455 bf35eecad64554b880023490c05ab6cb 503 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 355 364 - T 28-03-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CO689_RS02455 bf35eecad64554b880023490c05ab6cb 503 SUPERFAMILY SSF50615 11 94 5.1E-30 T 28-03-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CO689_RS02455 bf35eecad64554b880023490c05ab6cb 503 Pfam PF00306 ATP synthase alpha/beta chain, C terminal domain 371 494 1.5E-45 T 28-03-2018 IPR000793 ATP synthase, alpha subunit, C-terminal GO:0015986 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CO689_RS02455 bf35eecad64554b880023490c05ab6cb 503 Gene3D G3DSA:1.20.150.20 373 498 2.2E-48 T 28-03-2018 CO689_RS02455 bf35eecad64554b880023490c05ab6cb 503 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 27 92 4.5E-18 T 28-03-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CO689_RS02455 bf35eecad64554b880023490c05ab6cb 503 SUPERFAMILY SSF47917 372 499 4.71E-46 T 28-03-2018 CO689_RS11895 1ac0e06b99739ab5992b94a73566a06b 288 Gene3D G3DSA:3.40.50.970 5 72 4.7E-15 T 28-03-2018 CO689_RS11895 1ac0e06b99739ab5992b94a73566a06b 288 Gene3D G3DSA:3.40.50.970 73 287 1.5E-47 T 28-03-2018 CO689_RS11895 1ac0e06b99739ab5992b94a73566a06b 288 Pfam PF12367 Pyruvate ferredoxin oxidoreductase beta subunit C terminal 199 263 4.3E-22 T 28-03-2018 IPR032686 Pyruvate ferredoxin oxidoreductase beta subunit, C-terminal CO689_RS11895 1ac0e06b99739ab5992b94a73566a06b 288 SUPERFAMILY SSF52518 12 231 4.52E-77 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CO689_RS11895 1ac0e06b99739ab5992b94a73566a06b 288 TIGRFAM TIGR02177 PorB_KorB: 2-oxoacid:acceptor oxidoreductase, beta subunit, pyruvate/2-ketoisovalerate family 14 274 9.2E-97 T 28-03-2018 IPR011896 2-oxoacid:acceptor oxidoreductase, beta subunit, pyruvate/2-ketoisovalerate CO689_RS11895 1ac0e06b99739ab5992b94a73566a06b 288 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 48 195 7.1E-32 T 28-03-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 CO689_RS08610 2c0c4135acb9ca04291ae930d3bafe6f 238 Gene3D G3DSA:3.30.70.980 80 175 1.9E-26 T 28-03-2018 IPR026564 Transcriptional regulator TACO1-like, domain 3 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CO689_RS08610 2c0c4135acb9ca04291ae930d3bafe6f 238 Gene3D G3DSA:3.30.70.980 176 236 1.1E-9 T 28-03-2018 IPR026564 Transcriptional regulator TACO1-like, domain 3 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CO689_RS08610 2c0c4135acb9ca04291ae930d3bafe6f 238 Pfam PF01709 Transcriptional regulator 4 235 2.7E-84 T 28-03-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CO689_RS08610 2c0c4135acb9ca04291ae930d3bafe6f 238 TIGRFAM TIGR01033 TIGR01033: DNA-binding regulatory protein, YebC/PmpR family 1 235 2.6E-74 T 28-03-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CO689_RS08610 2c0c4135acb9ca04291ae930d3bafe6f 238 Hamap MF_00693 Probable transcriptional regulatory protein YebC [yebC]. 1 237 31.998 T 28-03-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CO689_RS08610 2c0c4135acb9ca04291ae930d3bafe6f 238 Gene3D G3DSA:1.10.10.200 2 76 2.2E-27 T 28-03-2018 IPR017856 Integrase, N-terminal zinc-binding domain-like CO689_RS08610 2c0c4135acb9ca04291ae930d3bafe6f 238 Hamap MF_00918 Probable transcriptional regulatory protein YeeN [yeeN]. 1 238 54.308 T 28-03-2018 IPR026562 Probable transcriptional regulatory protein YeeN CO689_RS08610 2c0c4135acb9ca04291ae930d3bafe6f 238 SUPERFAMILY SSF75625 1 237 5.76E-84 T 28-03-2018 IPR029072 YebC-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CO689_RS02535 c968515165dbe31eae48398ac00975a8 438 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 167 372 2.2E-20 T 28-03-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CO689_RS02535 c968515165dbe31eae48398ac00975a8 438 Gene3D G3DSA:3.40.50.300 140 426 6.3E-50 T 28-03-2018 CO689_RS02535 c968515165dbe31eae48398ac00975a8 438 SUPERFAMILY SSF50249 62 135 2.14E-20 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CO689_RS02535 c968515165dbe31eae48398ac00975a8 438 SMART SM00357 64 129 4.2E-13 T 28-03-2018 IPR011129 Cold shock domain GO:0003676 CO689_RS02535 c968515165dbe31eae48398ac00975a8 438 SMART SM00959 17 59 8.9E-8 T 28-03-2018 IPR011112 Rho termination factor, N-terminal GO:0006353 CO689_RS02535 c968515165dbe31eae48398ac00975a8 438 Gene3D G3DSA:2.40.50.140 15 137 2.6E-38 T 28-03-2018 CO689_RS02535 c968515165dbe31eae48398ac00975a8 438 TIGRFAM TIGR00767 rho: transcription termination factor Rho 19 424 8.9E-187 T 28-03-2018 IPR004665 Transcription termination factor Rho GO:0003723|GO:0005524|GO:0006353|GO:0008186 CO689_RS02535 c968515165dbe31eae48398ac00975a8 438 SMART SM00382 178 364 3.2E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain CO689_RS02535 c968515165dbe31eae48398ac00975a8 438 SUPERFAMILY SSF52540 101 380 5.28E-64 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CO689_RS02535 c968515165dbe31eae48398ac00975a8 438 SUPERFAMILY SSF68912 19 59 6.28E-6 T 28-03-2018 IPR011112 Rho termination factor, N-terminal GO:0006353 CO689_RS02535 c968515165dbe31eae48398ac00975a8 438 Pfam PF07498 Rho termination factor, N-terminal domain 19 59 7.0E-10 T 28-03-2018 IPR011112 Rho termination factor, N-terminal GO:0006353 CO689_RS02535 c968515165dbe31eae48398ac00975a8 438 Hamap MF_01884 Transcription termination factor Rho [rho]. 1 426 198.028 T 28-03-2018 IPR004665 Transcription termination factor Rho GO:0003723|GO:0005524|GO:0006353|GO:0008186 CO689_RS02535 c968515165dbe31eae48398ac00975a8 438 Pfam PF07497 Rho termination factor, RNA-binding domain 63 135 3.4E-28 T 28-03-2018 IPR011113 Rho termination factor, RNA-binding domain GO:0003723|GO:0006353 CO689_RS11575 84bed91406b7e40f8efa6f42cd104fbc 245 TIGRFAM TIGR00088 trmD: tRNA (guanine(37)-N(1))-methyltransferase 1 232 1.2E-102 T 28-03-2018 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 CO689_RS11575 84bed91406b7e40f8efa6f42cd104fbc 245 Pfam PF01746 tRNA (Guanine-1)-methyltransferase 23 219 8.5E-74 T 28-03-2018 IPR016009 tRNA methyltransferase TRMD/TRM10-type domain KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 CO689_RS11575 84bed91406b7e40f8efa6f42cd104fbc 245 Hamap MF_00605 tRNA (guanine-N(1)-)-methyltransferase [trmD]. 1 245 113.989 T 28-03-2018 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 CO689_RS11575 84bed91406b7e40f8efa6f42cd104fbc 245 Gene3D G3DSA:1.10.1270.20 168 245 3.3E-35 T 28-03-2018 CO689_RS11575 84bed91406b7e40f8efa6f42cd104fbc 245 SUPERFAMILY SSF75217 2 242 1.96E-105 T 28-03-2018 IPR029028 Alpha/beta knot methyltransferases CO689_RS11575 84bed91406b7e40f8efa6f42cd104fbc 245 Gene3D G3DSA:3.40.1280.10 1 167 1.4E-79 T 28-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal CO689_RS11575 84bed91406b7e40f8efa6f42cd104fbc 245 PIRSF PIRSF000386 1 245 8.7E-107 T 28-03-2018 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 CO689_RS05710 690f2cf0a20ae6cc5a011fb2bb7f6a27 397 Gene3D G3DSA:1.10.10.60 289 339 9.3E-12 T 28-03-2018 CO689_RS05710 690f2cf0a20ae6cc5a011fb2bb7f6a27 397 SUPERFAMILY SSF46689 350 394 3.12E-11 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CO689_RS05710 690f2cf0a20ae6cc5a011fb2bb7f6a27 397 Gene3D G3DSA:1.10.10.60 340 362 0.005 T 28-03-2018 CO689_RS05710 690f2cf0a20ae6cc5a011fb2bb7f6a27 397 Pfam PF12833 Helix-turn-helix domain 316 394 2.9E-21 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CO689_RS05710 690f2cf0a20ae6cc5a011fb2bb7f6a27 397 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 347 388 - T 28-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 CO689_RS05710 690f2cf0a20ae6cc5a011fb2bb7f6a27 397 SUPERFAMILY SSF46689 295 344 8.36E-7 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CO689_RS05710 690f2cf0a20ae6cc5a011fb2bb7f6a27 397 Gene3D G3DSA:1.10.10.60 363 397 1.7E-13 T 28-03-2018 CO689_RS05710 690f2cf0a20ae6cc5a011fb2bb7f6a27 397 SMART SM00342 310 392 2.5E-28 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CO689_RS05710 690f2cf0a20ae6cc5a011fb2bb7f6a27 397 TIGRFAM TIGR04094 adjacent_YSIRK: YSIRK-targeted surface antigen transcriptional regulator 7 392 1.1E-106 T 28-03-2018 IPR024022 Transcription regulator HTH, surface antigen CO689_RS05710 690f2cf0a20ae6cc5a011fb2bb7f6a27 397 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 376 392 5.6E-7 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CO689_RS05710 690f2cf0a20ae6cc5a011fb2bb7f6a27 397 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 361 376 5.6E-7 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CO689_RS00600 d23cdb1d69425fb70a20bb46d13d3d98 839 Pfam PF04851 Type III restriction enzyme, res subunit 34 173 4.3E-11 T 28-03-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 CO689_RS00600 d23cdb1d69425fb70a20bb46d13d3d98 839 Pfam PF13307 Helicase C-terminal domain 401 490 3.4E-8 T 28-03-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 CO689_RS00600 d23cdb1d69425fb70a20bb46d13d3d98 839 Gene3D G3DSA:3.40.50.300 8 297 2.7E-20 T 28-03-2018 CO689_RS00600 d23cdb1d69425fb70a20bb46d13d3d98 839 SUPERFAMILY SSF52540 27 171 1.3E-15 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CO689_RS00600 d23cdb1d69425fb70a20bb46d13d3d98 839 SMART SM00487 30 318 8.4E-8 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CO689_RS00600 d23cdb1d69425fb70a20bb46d13d3d98 839 SMART SM00491 361 476 1.0E-9 T 28-03-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 CO689_RS00600 d23cdb1d69425fb70a20bb46d13d3d98 839 SUPERFAMILY SSF52540 52 104 3.08E-11 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CO689_RS00600 d23cdb1d69425fb70a20bb46d13d3d98 839 SUPERFAMILY SSF52540 365 480 3.08E-11 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CO689_RS02845 215edc08a6e60283c5beddc5420c420a 341 Gene3D G3DSA:1.10.3470.10 13 341 7.6E-65 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CO689_RS02845 215edc08a6e60283c5beddc5420c420a 341 SUPERFAMILY SSF81345 12 336 1.23E-81 T 28-03-2018 IPR029022 ABC transporter, BtuC-like CO689_RS02845 215edc08a6e60283c5beddc5420c420a 341 Pfam PF01032 FecCD transport family 29 336 3.0E-91 T 28-03-2018 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 CO689_RS10615 641834babd385d4d8a80f3f0babb3774 424 PRINTS PR00131 Glycosyl hydrolase family 1 signature 347 358 1.4E-24 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CO689_RS10615 641834babd385d4d8a80f3f0babb3774 424 PRINTS PR00131 Glycosyl hydrolase family 1 signature 245 259 1.4E-24 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CO689_RS10615 641834babd385d4d8a80f3f0babb3774 424 PRINTS PR00131 Glycosyl hydrolase family 1 signature 326 334 1.4E-24 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CO689_RS10615 641834babd385d4d8a80f3f0babb3774 424 PRINTS PR00131 Glycosyl hydrolase family 1 signature 368 385 1.4E-24 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CO689_RS10615 641834babd385d4d8a80f3f0babb3774 424 PRINTS PR00131 Glycosyl hydrolase family 1 signature 392 404 1.4E-24 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CO689_RS10615 641834babd385d4d8a80f3f0babb3774 424 SUPERFAMILY SSF51445 118 419 2.44E-82 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CO689_RS10615 641834babd385d4d8a80f3f0babb3774 424 Pfam PF02378 Phosphotransferase system, EIIC 1 127 1.3E-15 T 28-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 CO689_RS10615 641834babd385d4d8a80f3f0babb3774 424 ProSitePatterns PS00572 Glycosyl hydrolases family 1 active site. 326 334 - T 28-03-2018 IPR018120 Glycoside hydrolase family 1, active site CO689_RS10615 641834babd385d4d8a80f3f0babb3774 424 Gene3D G3DSA:3.20.20.80 115 420 2.1E-78 T 28-03-2018 CO689_RS10615 641834babd385d4d8a80f3f0babb3774 424 Pfam PF00232 Glycosyl hydrolase family 1 121 418 1.6E-77 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CO689_RS07085 6441a6883aec900823e4cc3e8b275003 390 SUPERFAMILY SSF53383 26 373 3.72E-98 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CO689_RS07085 6441a6883aec900823e4cc3e8b275003 390 Gene3D G3DSA:3.90.1150.10 247 386 1.5E-35 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CO689_RS07085 6441a6883aec900823e4cc3e8b275003 390 Gene3D G3DSA:3.40.640.10 3 245 2.1E-50 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CO689_RS07085 6441a6883aec900823e4cc3e8b275003 390 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 17 372 2.3E-123 T 28-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 CO689_RS07085 6441a6883aec900823e4cc3e8b275003 390 PIRSF PIRSF001434 1 375 3.5E-122 T 28-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 CO689_RS07085 6441a6883aec900823e4cc3e8b275003 390 ProSitePatterns PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. 187 201 - T 28-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 CO689_RS03400 f1ea106417410af832e30746dc08fb10 571 Pfam PF01979 Amidohydrolase family 129 458 1.8E-79 T 28-03-2018 IPR006680 Amidohydrolase-related GO:0016787 CO689_RS03400 f1ea106417410af832e30746dc08fb10 571 Gene3D G3DSA:3.20.20.140 147 425 8.7E-151 T 28-03-2018 CO689_RS03400 f1ea106417410af832e30746dc08fb10 571 Gene3D G3DSA:3.20.20.140 426 557 1.4E-38 T 28-03-2018 CO689_RS03400 f1ea106417410af832e30746dc08fb10 571 ProSitePatterns PS01120 Urease nickel ligands signature. 131 144 - T 28-03-2018 IPR029754 Urease nickel binding site GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CO689_RS03400 f1ea106417410af832e30746dc08fb10 571 TIGRFAM TIGR01792 urease_alph: urease, alpha subunit 4 571 0.0 T 28-03-2018 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CO689_RS03400 f1ea106417410af832e30746dc08fb10 571 SUPERFAMILY SSF51556 485 571 1.3E-189 T 28-03-2018 IPR032466 Metal-dependent hydrolase CO689_RS03400 f1ea106417410af832e30746dc08fb10 571 SUPERFAMILY SSF51556 133 436 1.3E-189 T 28-03-2018 IPR032466 Metal-dependent hydrolase CO689_RS03400 f1ea106417410af832e30746dc08fb10 571 PRINTS PR01752 Urea amidohydrolase (urease) protein signature 299 316 2.4E-33 T 28-03-2018 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CO689_RS03400 f1ea106417410af832e30746dc08fb10 571 PRINTS PR01752 Urea amidohydrolase (urease) protein signature 405 420 2.4E-33 T 28-03-2018 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CO689_RS03400 f1ea106417410af832e30746dc08fb10 571 PRINTS PR01752 Urea amidohydrolase (urease) protein signature 338 354 2.4E-33 T 28-03-2018 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CO689_RS03400 f1ea106417410af832e30746dc08fb10 571 PRINTS PR01752 Urea amidohydrolase (urease) protein signature 431 444 2.4E-33 T 28-03-2018 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CO689_RS03400 f1ea106417410af832e30746dc08fb10 571 Hamap MF_01953 Urease subunit alpha [ureC]. 3 571 55.037 T 28-03-2018 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CO689_RS03400 f1ea106417410af832e30746dc08fb10 571 Pfam PF00449 Urease alpha-subunit, N-terminal domain 4 123 8.0E-50 T 28-03-2018 IPR011612 Urease alpha-subunit, N-terminal domain KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CO689_RS03400 f1ea106417410af832e30746dc08fb10 571 SUPERFAMILY SSF51338 426 473 2.54E-53 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CO689_RS03400 f1ea106417410af832e30746dc08fb10 571 SUPERFAMILY SSF51338 4 133 2.54E-53 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CO689_RS03400 f1ea106417410af832e30746dc08fb10 571 ProSitePatterns PS00145 Urease active site. 321 337 - T 28-03-2018 IPR017950 Urease active site GO:0009039 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CO689_RS03400 f1ea106417410af832e30746dc08fb10 571 Gene3D G3DSA:2.30.40.10 68 146 1.8E-14 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CO689_RS03810 3eb1f14b10f55795fda5dc5a997fc66c 469 SMART SM00388 239 304 2.6E-11 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CO689_RS03810 3eb1f14b10f55795fda5dc5a997fc66c 469 PRINTS PR00344 Bacterial sensor protein C-terminal signature 441 454 8.3E-14 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CO689_RS03810 3eb1f14b10f55795fda5dc5a997fc66c 469 PRINTS PR00344 Bacterial sensor protein C-terminal signature 417 435 8.3E-14 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CO689_RS03810 3eb1f14b10f55795fda5dc5a997fc66c 469 PRINTS PR00344 Bacterial sensor protein C-terminal signature 404 414 8.3E-14 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CO689_RS03810 3eb1f14b10f55795fda5dc5a997fc66c 469 PRINTS PR00344 Bacterial sensor protein C-terminal signature 386 400 8.3E-14 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CO689_RS03810 3eb1f14b10f55795fda5dc5a997fc66c 469 Pfam PF00512 His Kinase A (phospho-acceptor) domain 240 303 3.8E-10 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CO689_RS03810 3eb1f14b10f55795fda5dc5a997fc66c 469 SUPERFAMILY SSF158472 187 235 7.06E-10 T 28-03-2018 CO689_RS03810 3eb1f14b10f55795fda5dc5a997fc66c 469 SMART SM00387 348 457 7.7E-33 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CO689_RS03810 3eb1f14b10f55795fda5dc5a997fc66c 469 Pfam PF00672 HAMP domain 187 234 5.7E-7 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CO689_RS03810 3eb1f14b10f55795fda5dc5a997fc66c 469 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 350 456 1.0E-21 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CO689_RS03810 3eb1f14b10f55795fda5dc5a997fc66c 469 SMART SM00304 186 238 3.4E-7 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CO689_RS03810 3eb1f14b10f55795fda5dc5a997fc66c 469 Gene3D G3DSA:3.30.565.10 324 469 9.7E-39 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CO689_RS03810 3eb1f14b10f55795fda5dc5a997fc66c 469 Gene3D G3DSA:1.10.287.130 229 299 6.5E-14 T 28-03-2018 CO689_RS03810 3eb1f14b10f55795fda5dc5a997fc66c 469 SUPERFAMILY SSF55874 295 460 3.54E-36 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CO689_RS03810 3eb1f14b10f55795fda5dc5a997fc66c 469 SUPERFAMILY SSF47384 222 304 2.55E-15 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CO689_RS03035 23428d86fd88382467d7f822b3407f87 37 SUPERFAMILY SSF57840 1 37 5.62E-17 T 28-03-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CO689_RS03035 23428d86fd88382467d7f822b3407f87 37 TIGRFAM TIGR01022 rpmJ_bact: ribosomal protein bL36 1 37 7.0E-24 T 28-03-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CO689_RS03035 23428d86fd88382467d7f822b3407f87 37 ProSitePatterns PS00828 Ribosomal protein L36 signature. 11 36 - T 28-03-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CO689_RS03035 23428d86fd88382467d7f822b3407f87 37 ProDom PD002101 RIBOSOMAL L36 RIBONUCLEOPROTEIN 50S CHLOROPLAST PLASTID B SUBUNIT DIRECT SEQUENCING 10 37 2.0E-8 T 28-03-2018 CO689_RS03035 23428d86fd88382467d7f822b3407f87 37 Hamap MF_00251 50S ribosomal protein L36 [rpmJ]. 1 37 17.547 T 28-03-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CO689_RS03035 23428d86fd88382467d7f822b3407f87 37 Pfam PF00444 Ribosomal protein L36 1 37 8.6E-20 T 28-03-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CO689_RS11685 df9a0297172516c997470084948a18f8 240 Hamap MF_01220_B Uridylate kinase [pyrH]. 5 239 43.594 T 28-03-2018 IPR015963 Uridylate kinase, bacteria GO:0005737|GO:0006221|GO:0033862 KEGG: 00240+2.7.4.22 CO689_RS11685 df9a0297172516c997470084948a18f8 240 Pfam PF00696 Amino acid kinase family 8 217 2.5E-28 T 28-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase CO689_RS11685 df9a0297172516c997470084948a18f8 240 Gene3D G3DSA:3.40.1160.10 1 240 1.6E-43 T 28-03-2018 CO689_RS11685 df9a0297172516c997470084948a18f8 240 SUPERFAMILY SSF53633 6 239 2.09E-73 T 28-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase CO689_RS11685 df9a0297172516c997470084948a18f8 240 PIRSF PIRSF005650 2 240 6.0E-95 T 28-03-2018 IPR011817 Uridylate kinase GO:0006221|GO:0009041 KEGG: 00240+2.7.4.22 CO689_RS11685 df9a0297172516c997470084948a18f8 240 TIGRFAM TIGR02075 pyrH_bact: UMP kinase 7 238 1.4E-103 T 28-03-2018 IPR015963 Uridylate kinase, bacteria GO:0005737|GO:0006221|GO:0033862 KEGG: 00240+2.7.4.22 CO689_RS04380 92a50850a8628146b71fb5ecbedaacb8 344 Gene3D G3DSA:3.40.50.2300 173 320 5.0E-28 T 28-03-2018 CO689_RS04380 92a50850a8628146b71fb5ecbedaacb8 344 Pfam PF00356 Bacterial regulatory proteins, lacI family 7 53 4.4E-9 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CO689_RS04380 92a50850a8628146b71fb5ecbedaacb8 344 SUPERFAMILY SSF47413 5 61 1.9E-9 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CO689_RS04380 92a50850a8628146b71fb5ecbedaacb8 344 SMART SM00354 5 76 1.0E-8 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CO689_RS04380 92a50850a8628146b71fb5ecbedaacb8 344 Gene3D G3DSA:3.40.50.2300 59 172 3.1E-25 T 28-03-2018 CO689_RS04380 92a50850a8628146b71fb5ecbedaacb8 344 Gene3D G3DSA:1.10.260.40 7 58 6.6E-13 T 28-03-2018 CO689_RS04380 92a50850a8628146b71fb5ecbedaacb8 344 Pfam PF13377 Periplasmic binding protein-like domain 170 337 4.4E-22 T 28-03-2018 CO689_RS04380 92a50850a8628146b71fb5ecbedaacb8 344 SUPERFAMILY SSF53822 65 337 6.09E-46 T 28-03-2018 IPR028082 Periplasmic binding protein-like I CO689_RS00250 e0b7c0a4595e482ac89054bdf84cdf5c 325 Gene3D G3DSA:3.40.50.2300 176 291 4.2E-32 T 28-03-2018 CO689_RS00250 e0b7c0a4595e482ac89054bdf84cdf5c 325 SUPERFAMILY SSF47413 1 59 1.56E-16 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CO689_RS00250 e0b7c0a4595e482ac89054bdf84cdf5c 325 Pfam PF00532 Periplasmic binding proteins and sugar binding domain of LacI family 62 297 1.2E-29 T 28-03-2018 IPR001761 Periplasmic binding protein/LacI sugar binding domain CO689_RS00250 e0b7c0a4595e482ac89054bdf84cdf5c 325 Gene3D G3DSA:3.40.50.2300 55 175 1.2E-28 T 28-03-2018 CO689_RS00250 e0b7c0a4595e482ac89054bdf84cdf5c 325 Gene3D G3DSA:1.10.260.40 2 54 4.4E-20 T 28-03-2018 CO689_RS00250 e0b7c0a4595e482ac89054bdf84cdf5c 325 Pfam PF00356 Bacterial regulatory proteins, lacI family 3 48 5.4E-16 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CO689_RS00250 e0b7c0a4595e482ac89054bdf84cdf5c 325 SUPERFAMILY SSF53822 61 324 2.36E-58 T 28-03-2018 IPR028082 Periplasmic binding protein-like I CO689_RS00250 e0b7c0a4595e482ac89054bdf84cdf5c 325 SMART SM00354 1 71 6.8E-29 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CO689_RS00250 e0b7c0a4595e482ac89054bdf84cdf5c 325 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 13 23 2.6E-6 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CO689_RS00250 e0b7c0a4595e482ac89054bdf84cdf5c 325 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 3 13 2.6E-6 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CO689_RS00250 e0b7c0a4595e482ac89054bdf84cdf5c 325 ProSitePatterns PS00356 LacI-type HTH domain signature. 4 22 - T 28-03-2018 CO689_RS04540 12cd34a2a22ee698b7845ea859fe9128 251 ProSitePatterns PS01087 Radical activating enzymes signature. 17 38 - T 28-03-2018 IPR001989 Radical-activating enzyme, conserved site GO:0016491|GO:0051539|GO:0055114 CO689_RS04540 12cd34a2a22ee698b7845ea859fe9128 251 Pfam PF04055 Radical SAM superfamily 23 188 4.0E-30 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CO689_RS04540 12cd34a2a22ee698b7845ea859fe9128 251 TIGRFAM TIGR02493 PFLA: pyruvate formate-lyase 1-activating enzyme 5 240 1.3E-96 T 28-03-2018 IPR012838 Pyruvate formate-lyase activating enzyme GO:0043365|GO:0055114 CO689_RS04540 12cd34a2a22ee698b7845ea859fe9128 251 Gene3D G3DSA:3.80.30.10 68 250 3.7E-40 T 28-03-2018 CO689_RS04540 12cd34a2a22ee698b7845ea859fe9128 251 Pfam PF13353 4Fe-4S single cluster domain 15 145 3.7E-18 T 28-03-2018 CO689_RS04540 12cd34a2a22ee698b7845ea859fe9128 251 PIRSF PIRSF000371 2 48 6.8E-12 T 28-03-2018 IPR012839 Organic radical enzyme activase GO:0016491|GO:0055114 CO689_RS04540 12cd34a2a22ee698b7845ea859fe9128 251 PIRSF PIRSF000371 43 249 1.9E-47 T 28-03-2018 IPR012839 Organic radical enzyme activase GO:0016491|GO:0055114 CO689_RS04540 12cd34a2a22ee698b7845ea859fe9128 251 SUPERFAMILY SSF102114 21 224 1.23E-27 T 28-03-2018 CO689_RS12240 144d3e22d0e8b8c3bab5dfc5b986e648 666 Hamap MF_00939 DNA topoisomerase 4 subunit B [parE]. 7 642 49.944 T 28-03-2018 IPR005740 DNA topoisomerase 4 subunit B, Firmicutes/Mollicutes GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 CO689_RS12240 144d3e22d0e8b8c3bab5dfc5b986e648 666 Pfam PF00986 DNA gyrase B subunit, carboxyl terminus 572 633 8.0E-29 T 28-03-2018 IPR002288 DNA gyrase B subunit, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 CO689_RS12240 144d3e22d0e8b8c3bab5dfc5b986e648 666 SUPERFAMILY SSF56719 402 638 1.62E-83 T 28-03-2018 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Reactome: R-HSA-4615885 CO689_RS12240 144d3e22d0e8b8c3bab5dfc5b986e648 666 PRINTS PR00418 DNA topoisomerase II family signature 494 510 3.0E-68 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CO689_RS12240 144d3e22d0e8b8c3bab5dfc5b986e648 666 PRINTS PR00418 DNA topoisomerase II family signature 532 544 3.0E-68 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CO689_RS12240 144d3e22d0e8b8c3bab5dfc5b986e648 666 PRINTS PR00418 DNA topoisomerase II family signature 512 529 3.0E-68 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CO689_RS12240 144d3e22d0e8b8c3bab5dfc5b986e648 666 PRINTS PR00418 DNA topoisomerase II family signature 115 129 3.0E-68 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CO689_RS12240 144d3e22d0e8b8c3bab5dfc5b986e648 666 PRINTS PR00418 DNA topoisomerase II family signature 73 86 3.0E-68 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CO689_RS12240 144d3e22d0e8b8c3bab5dfc5b986e648 666 PRINTS PR00418 DNA topoisomerase II family signature 272 285 3.0E-68 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CO689_RS12240 144d3e22d0e8b8c3bab5dfc5b986e648 666 PRINTS PR00418 DNA topoisomerase II family signature 38 53 3.0E-68 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CO689_RS12240 144d3e22d0e8b8c3bab5dfc5b986e648 666 PRINTS PR00418 DNA topoisomerase II family signature 428 442 3.0E-68 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CO689_RS12240 144d3e22d0e8b8c3bab5dfc5b986e648 666 PRINTS PR00418 DNA topoisomerase II family signature 576 592 3.0E-68 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CO689_RS12240 144d3e22d0e8b8c3bab5dfc5b986e648 666 SUPERFAMILY SSF54211 226 397 3.22E-52 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CO689_RS12240 144d3e22d0e8b8c3bab5dfc5b986e648 666 Gene3D G3DSA:3.30.230.10 226 398 2.7E-55 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CO689_RS12240 144d3e22d0e8b8c3bab5dfc5b986e648 666 TIGRFAM TIGR01058 parE_Gpos: DNA topoisomerase IV, B subunit 7 645 0.0 T 28-03-2018 IPR005740 DNA topoisomerase 4 subunit B, Firmicutes/Mollicutes GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 CO689_RS12240 144d3e22d0e8b8c3bab5dfc5b986e648 666 ProSitePatterns PS00177 DNA topoisomerase II signature. 430 438 - T 28-03-2018 IPR018522 DNA topoisomerase, type IIA, conserved site GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CO689_RS12240 144d3e22d0e8b8c3bab5dfc5b986e648 666 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 34 177 1.2E-22 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CO689_RS12240 144d3e22d0e8b8c3bab5dfc5b986e648 666 Gene3D G3DSA:3.30.565.10 21 225 1.1E-73 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CO689_RS12240 144d3e22d0e8b8c3bab5dfc5b986e648 666 Pfam PF00204 DNA gyrase B 226 396 4.5E-58 T 28-03-2018 IPR013506 DNA topoisomerase, type IIA, subunit B, domain 2 GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CO689_RS12240 144d3e22d0e8b8c3bab5dfc5b986e648 666 SMART SM00387 34 178 2.8E-28 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CO689_RS12240 144d3e22d0e8b8c3bab5dfc5b986e648 666 SMART SM00433 38 637 0.0 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CO689_RS12240 144d3e22d0e8b8c3bab5dfc5b986e648 666 Gene3D G3DSA:3.40.50.670 407 641 3.7E-90 T 28-03-2018 IPR013759 DNA topoisomerase, type IIA, central domain GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CO689_RS12240 144d3e22d0e8b8c3bab5dfc5b986e648 666 SUPERFAMILY SSF55874 9 220 1.44E-66 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CO689_RS12240 144d3e22d0e8b8c3bab5dfc5b986e648 666 Pfam PF01751 Toprim domain 427 537 3.7E-17 T 28-03-2018 IPR006171 TOPRIM domain CO689_RS12240 144d3e22d0e8b8c3bab5dfc5b986e648 666 PRINTS PR01159 DNA gyrase subunit B signature 380 400 6.1E-55 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CO689_RS12240 144d3e22d0e8b8c3bab5dfc5b986e648 666 PRINTS PR01159 DNA gyrase subunit B signature 184 199 6.1E-55 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CO689_RS12240 144d3e22d0e8b8c3bab5dfc5b986e648 666 PRINTS PR01159 DNA gyrase subunit B signature 366 380 6.1E-55 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CO689_RS12240 144d3e22d0e8b8c3bab5dfc5b986e648 666 PRINTS PR01159 DNA gyrase subunit B signature 478 487 6.1E-55 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CO689_RS12240 144d3e22d0e8b8c3bab5dfc5b986e648 666 PRINTS PR01159 DNA gyrase subunit B signature 597 609 6.1E-55 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CO689_RS12240 144d3e22d0e8b8c3bab5dfc5b986e648 666 PRINTS PR01159 DNA gyrase subunit B signature 225 247 6.1E-55 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CO689_RS12240 144d3e22d0e8b8c3bab5dfc5b986e648 666 PRINTS PR01159 DNA gyrase subunit B signature 316 332 6.1E-55 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CO689_RS12240 144d3e22d0e8b8c3bab5dfc5b986e648 666 PRINTS PR01159 DNA gyrase subunit B signature 199 212 6.1E-55 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CO689_RS12240 144d3e22d0e8b8c3bab5dfc5b986e648 666 PRINTS PR01159 DNA gyrase subunit B signature 613 629 6.1E-55 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CO689_RS12240 144d3e22d0e8b8c3bab5dfc5b986e648 666 PRINTS PR01159 DNA gyrase subunit B signature 9 19 6.1E-55 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CO689_RS08350 6a1e91e198b13868f6cb2c12196ca1d8 301 SUPERFAMILY SSF53807 45 297 1.18E-53 T 28-03-2018 CO689_RS08350 6a1e91e198b13868f6cb2c12196ca1d8 301 Pfam PF01497 Periplasmic binding protein 47 272 2.2E-32 T 28-03-2018 IPR002491 ABC transporter periplasmic binding domain GO:0005488 CO689_RS08350 6a1e91e198b13868f6cb2c12196ca1d8 301 Gene3D G3DSA:3.40.50.1980 30 145 5.5E-23 T 28-03-2018 CO689_RS08350 6a1e91e198b13868f6cb2c12196ca1d8 301 Gene3D G3DSA:3.40.50.1980 146 298 3.9E-33 T 28-03-2018 CO689_RS02500 f899f1f2cf9297ed7a5109e271bfba17 175 Hamap MF_00800 UPF0340 protein . 1 175 88.477 T 28-03-2018 IPR006340 Protein of unknown function DUF436 CO689_RS02500 f899f1f2cf9297ed7a5109e271bfba17 175 Pfam PF04260 Protein of unknown function (DUF436) 6 173 3.8E-75 T 28-03-2018 IPR006340 Protein of unknown function DUF436 CO689_RS02500 f899f1f2cf9297ed7a5109e271bfba17 175 ProDom PD102102 UPF0340 3D-STRUCTURE YWLG SMU.87 STU1894 BT9727_4999 TRANSFERASE TTE0860 SPY1898/M5005_SPY1614 TT1679 20 173 1.0E-66 T 28-03-2018 IPR006340 Protein of unknown function DUF436 CO689_RS02500 f899f1f2cf9297ed7a5109e271bfba17 175 PIRSF PIRSF007510 1 175 2.0E-81 T 28-03-2018 IPR006340 Protein of unknown function DUF436 CO689_RS02500 f899f1f2cf9297ed7a5109e271bfba17 175 SUPERFAMILY SSF110710 3 174 1.05E-74 T 28-03-2018 CO689_RS02500 f899f1f2cf9297ed7a5109e271bfba17 175 TIGRFAM TIGR01440 TIGR01440: TIGR01440 family protein 3 173 2.9E-83 T 28-03-2018 IPR006340 Protein of unknown function DUF436 CO689_RS02500 f899f1f2cf9297ed7a5109e271bfba17 175 Gene3D G3DSA:3.40.50.10360 1 175 9.9E-77 T 28-03-2018 IPR006340 Protein of unknown function DUF436 CO689_RS12565 176418823b3c0223d39ad5129ad64769 220 Pfam PF00486 Transcriptional regulatory protein, C terminal 143 217 2.2E-27 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CO689_RS12565 176418823b3c0223d39ad5129ad64769 220 Gene3D G3DSA:1.10.10.10 117 220 2.6E-31 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS12565 176418823b3c0223d39ad5129ad64769 220 SMART SM00448 2 112 2.3E-43 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CO689_RS12565 176418823b3c0223d39ad5129ad64769 220 SMART SM00862 143 218 3.0E-27 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CO689_RS12565 176418823b3c0223d39ad5129ad64769 220 SUPERFAMILY SSF52172 3 118 2.28E-40 T 28-03-2018 IPR011006 CheY-like superfamily CO689_RS12565 176418823b3c0223d39ad5129ad64769 220 SUPERFAMILY SSF46894 119 218 7.09E-31 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CO689_RS12565 176418823b3c0223d39ad5129ad64769 220 Gene3D G3DSA:3.40.50.2300 1 116 8.2E-35 T 28-03-2018 CO689_RS12565 176418823b3c0223d39ad5129ad64769 220 Pfam PF00072 Response regulator receiver domain 4 113 4.9E-29 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CO689_RS06600 689be77f2c8c5f9da33cf0a6c2fe67cc 318 SUPERFAMILY SSF52283 3 133 2.08E-37 T 28-03-2018 CO689_RS06600 689be77f2c8c5f9da33cf0a6c2fe67cc 318 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 108 285 8.3E-60 T 28-03-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 CO689_RS06600 689be77f2c8c5f9da33cf0a6c2fe67cc 318 Gene3D G3DSA:3.40.50.720 1 113 6.5E-38 T 28-03-2018 CO689_RS06600 689be77f2c8c5f9da33cf0a6c2fe67cc 318 Gene3D G3DSA:3.40.50.720 114 288 3.0E-53 T 28-03-2018 CO689_RS06600 689be77f2c8c5f9da33cf0a6c2fe67cc 318 SUPERFAMILY SSF51735 99 285 1.2E-56 T 28-03-2018 IPR016040 NAD(P)-binding domain CO689_RS06600 689be77f2c8c5f9da33cf0a6c2fe67cc 318 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 4 317 1.9E-36 T 28-03-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 CO689_RS13830 108835842aaf13c03a600e17aa89df5e 453 Pfam PF00324 Amino acid permease 13 447 5.3E-106 T 28-03-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0006810|GO:0016020|GO:0055085 CO689_RS13830 108835842aaf13c03a600e17aa89df5e 453 PIRSF PIRSF006060 1 452 4.6E-66 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CO689_RS02625 fbcebb42b06d3ae522b77adfd5d7b3a6 148 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 29 45 1.3E-14 T 28-03-2018 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 CO689_RS02625 fbcebb42b06d3ae522b77adfd5d7b3a6 148 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 53 69 1.3E-14 T 28-03-2018 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 CO689_RS02625 fbcebb42b06d3ae522b77adfd5d7b3a6 148 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 124 142 1.3E-14 T 28-03-2018 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 CO689_RS02625 fbcebb42b06d3ae522b77adfd5d7b3a6 148 PIRSF PIRSF005900 1 148 1.8E-49 T 28-03-2018 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 CO689_RS02625 fbcebb42b06d3ae522b77adfd5d7b3a6 148 Gene3D G3DSA:1.20.1260.10 1 148 4.2E-47 T 28-03-2018 IPR012347 Ferritin-related CO689_RS02625 fbcebb42b06d3ae522b77adfd5d7b3a6 148 Pfam PF00210 Ferritin-like domain 9 148 3.3E-32 T 28-03-2018 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 CO689_RS02625 fbcebb42b06d3ae522b77adfd5d7b3a6 148 ProSitePatterns PS00818 Dps protein family signature 1. 29 45 - T 28-03-2018 IPR023188 DNA-binding protein Dps, conserved site GO:0016722|GO:0055114 CO689_RS02625 fbcebb42b06d3ae522b77adfd5d7b3a6 148 ProSitePatterns PS00819 Dps protein family signature 2. 55 69 - T 28-03-2018 IPR023188 DNA-binding protein Dps, conserved site GO:0016722|GO:0055114 CO689_RS02625 fbcebb42b06d3ae522b77adfd5d7b3a6 148 SUPERFAMILY SSF47240 4 148 5.93E-45 T 28-03-2018 IPR009078 Ferritin-like superfamily CO689_RS12645 e62df28b6e95667febc8b22fd5db3a22 130 Pfam PF13456 Reverse transcriptase-like 6 124 1.3E-14 T 28-03-2018 CO689_RS12645 e62df28b6e95667febc8b22fd5db3a22 130 Gene3D G3DSA:3.30.420.10 1 130 1.5E-20 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CO689_RS12645 e62df28b6e95667febc8b22fd5db3a22 130 SUPERFAMILY SSF53098 2 122 4.43E-22 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CO689_RS05360 fd18a762f1eabdf9c0cc619397c55fc0 496 SUPERFAMILY SSF53720 8 488 3.93E-170 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CO689_RS05360 fd18a762f1eabdf9c0cc619397c55fc0 496 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 254 261 - T 28-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 CO689_RS05360 fd18a762f1eabdf9c0cc619397c55fc0 496 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 282 293 - T 28-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 CO689_RS05360 fd18a762f1eabdf9c0cc619397c55fc0 496 TIGRFAM TIGR01804 BADH: betaine-aldehyde dehydrogenase 12 477 8.0E-230 T 28-03-2018 IPR011264 Betaine aldehyde dehydrogenase GO:0008802|GO:0019285|GO:0046872 KEGG: 00260+1.2.1.8|MetaCyc: PWY-3722|MetaCyc: PWY-7494 CO689_RS05360 fd18a762f1eabdf9c0cc619397c55fc0 496 Pfam PF00171 Aldehyde dehydrogenase family 17 482 4.7E-174 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CO689_RS05360 fd18a762f1eabdf9c0cc619397c55fc0 496 Gene3D G3DSA:3.40.605.10 3 272 4.1E-94 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CO689_RS05360 fd18a762f1eabdf9c0cc619397c55fc0 496 Gene3D G3DSA:3.40.309.10 273 468 7.2E-77 T 28-03-2018 CO689_RS01660 d182fd4302bca81c1337e1ff5c655df3 104 Gene3D G3DSA:2.30.30.340 52 104 3.1E-15 T 28-03-2018 CO689_RS01660 d182fd4302bca81c1337e1ff5c655df3 104 SUPERFAMILY SSF101697 2 103 1.01E-33 T 28-03-2018 IPR014938 Protein of unknown function DUF1811 CO689_RS01660 d182fd4302bca81c1337e1ff5c655df3 104 Pfam PF08838 Protein of unknown function (DUF1811) 5 103 1.7E-36 T 28-03-2018 IPR014938 Protein of unknown function DUF1811 CO689_RS01660 d182fd4302bca81c1337e1ff5c655df3 104 Gene3D G3DSA:1.10.287.880 2 51 4.2E-20 T 28-03-2018 CO689_RS00675 3b87fd0b05dd96f5e2f4151c646bfc2c 1236 Pfam PF17210 SdrD B-like domain 505 617 4.1E-31 T 28-03-2018 IPR033764 SD-repeat containing protein, B domain CO689_RS00675 3b87fd0b05dd96f5e2f4151c646bfc2c 1236 Pfam PF17210 SdrD B-like domain 735 836 6.6E-31 T 28-03-2018 IPR033764 SD-repeat containing protein, B domain CO689_RS00675 3b87fd0b05dd96f5e2f4151c646bfc2c 1236 Pfam PF17210 SdrD B-like domain 624 727 3.0E-33 T 28-03-2018 IPR033764 SD-repeat containing protein, B domain CO689_RS00675 3b87fd0b05dd96f5e2f4151c646bfc2c 1236 Pfam PF10425 C-terminus of bacterial fibrinogen-binding adhesin 347 476 3.5E-11 T 28-03-2018 IPR011266 Fibrinogen-binding domain 2 GO:0005618|GO:0007155 CO689_RS00675 3b87fd0b05dd96f5e2f4151c646bfc2c 1236 Pfam PF00746 LPXTG cell wall anchor motif 1192 1232 3.3E-10 T 28-03-2018 IPR019948 Gram-positive LPXTG cell wall anchor CO689_RS00675 3b87fd0b05dd96f5e2f4151c646bfc2c 1236 SUPERFAMILY SSF117074 501 589 6.67E-22 T 28-03-2018 CO689_RS00675 3b87fd0b05dd96f5e2f4151c646bfc2c 1236 Gene3D G3DSA:2.60.40.1280 183 339 7.0E-32 T 28-03-2018 IPR011252 Fibrogen-binding domain 1 GO:0005618|GO:0007155 CO689_RS00675 3b87fd0b05dd96f5e2f4151c646bfc2c 1236 SUPERFAMILY SSF117074 606 704 7.06E-25 T 28-03-2018 CO689_RS00675 3b87fd0b05dd96f5e2f4151c646bfc2c 1236 Gene3D G3DSA:2.60.40.10 733 1126 1.1E-21 T 28-03-2018 IPR013783 Immunoglobulin-like fold CO689_RS00675 3b87fd0b05dd96f5e2f4151c646bfc2c 1236 Gene3D G3DSA:2.60.40.10 501 621 1.2E-26 T 28-03-2018 IPR013783 Immunoglobulin-like fold CO689_RS00675 3b87fd0b05dd96f5e2f4151c646bfc2c 1236 Gene3D G3DSA:2.60.40.10 622 732 7.0E-27 T 28-03-2018 IPR013783 Immunoglobulin-like fold CO689_RS00675 3b87fd0b05dd96f5e2f4151c646bfc2c 1236 SUPERFAMILY SSF49401 188 338 1.49E-31 T 28-03-2018 IPR008966 Adhesion domain CO689_RS00675 3b87fd0b05dd96f5e2f4151c646bfc2c 1236 SUPERFAMILY SSF117074 711 808 8.11E-23 T 28-03-2018 CO689_RS00675 3b87fd0b05dd96f5e2f4151c646bfc2c 1236 Gene3D G3DSA:2.60.40.1290 345 485 1.0E-21 T 28-03-2018 CO689_RS00675 3b87fd0b05dd96f5e2f4151c646bfc2c 1236 SUPERFAMILY SSF49401 337 526 1.04E-33 T 28-03-2018 IPR008966 Adhesion domain CO689_RS00675 3b87fd0b05dd96f5e2f4151c646bfc2c 1236 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 1197 1229 1.3E-6 T 28-03-2018 CO689_RS13630 3a005c5d9c3ea91391713fea7aede43a 260 Gene3D G3DSA:3.30.460.10 8 152 2.5E-12 T 28-03-2018 CO689_RS13630 3a005c5d9c3ea91391713fea7aede43a 260 PIRSF PIRSF000819 12 259 1.7E-71 T 28-03-2018 IPR024172 Streptomycin 3''-adenylyltransferase GO:0009012|GO:0046677 CO689_RS13630 3a005c5d9c3ea91391713fea7aede43a 260 Pfam PF13427 Domain of unknown function (DUF4111) 153 253 1.2E-33 T 28-03-2018 IPR025184 Domain of unknown function DUF4111 CO689_RS13630 3a005c5d9c3ea91391713fea7aede43a 260 Pfam PF01909 Nucleotidyltransferase domain 16 100 6.3E-12 T 28-03-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 CO689_RS13630 3a005c5d9c3ea91391713fea7aede43a 260 SUPERFAMILY SSF81301 17 102 1.74E-12 T 28-03-2018 CO689_RS02585 a8f00c1511e9be7099f1ce6a4f2ebe6e 269 TIGRFAM TIGR00555 panK_eukar: pantothenate kinase 1 264 2.4E-79 T 28-03-2018 IPR004567 Type II pantothenate kinase GO:0004594|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961|Reactome: R-HSA-196783 CO689_RS02585 a8f00c1511e9be7099f1ce6a4f2ebe6e 269 Hamap MF_01273 Type II pantothenate kinase [coaW]. 1 265 47.425 T 28-03-2018 IPR011602 Type II pantothenate kinase, bacterial GO:0004594|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 CO689_RS02585 a8f00c1511e9be7099f1ce6a4f2ebe6e 269 Pfam PF03630 Fumble 66 263 4.2E-22 T 28-03-2018 IPR004567 Type II pantothenate kinase GO:0004594|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961|Reactome: R-HSA-196783 CO689_RS02585 a8f00c1511e9be7099f1ce6a4f2ebe6e 269 Gene3D G3DSA:3.30.420.40 1 128 1.8E-4 T 28-03-2018 CO689_RS02585 a8f00c1511e9be7099f1ce6a4f2ebe6e 269 PIRSF PIRSF036940 1 267 1.7E-117 T 28-03-2018 IPR011602 Type II pantothenate kinase, bacterial GO:0004594|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 CO689_RS02585 a8f00c1511e9be7099f1ce6a4f2ebe6e 269 SUPERFAMILY SSF53067 1 265 2.72E-57 T 28-03-2018 CO689_RS03135 9344b97b028745b7e25239267668fa91 277 TIGRFAM TIGR01171 rplB_bact: ribosomal protein uL2 3 275 2.4E-137 T 28-03-2018 IPR005880 Ribosomal protein L2, bacterial/organellar-type GO:0003723|GO:0003735|GO:0006412|GO:0015934|GO:0016740 CO689_RS03135 9344b97b028745b7e25239267668fa91 277 Pfam PF03947 Ribosomal Proteins L2, C-terminal domain 125 251 7.4E-56 T 28-03-2018 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 CO689_RS03135 9344b97b028745b7e25239267668fa91 277 Pfam PF00181 Ribosomal Proteins L2, RNA binding domain 42 117 9.9E-34 T 28-03-2018 IPR022666 Ribosomal Proteins L2, RNA binding domain GO:0003735|GO:0005622|GO:0005840|GO:0006412 CO689_RS03135 9344b97b028745b7e25239267668fa91 277 Hamap MF_01320_B 50S ribosomal protein L2 [rplB]. 1 275 49.143 T 28-03-2018 IPR005880 Ribosomal protein L2, bacterial/organellar-type GO:0003723|GO:0003735|GO:0006412|GO:0015934|GO:0016740 CO689_RS03135 9344b97b028745b7e25239267668fa91 277 SMART SM01382 124 253 5.2E-93 T 28-03-2018 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 CO689_RS03135 9344b97b028745b7e25239267668fa91 277 Gene3D G3DSA:4.10.950.10 197 275 7.8E-33 T 28-03-2018 IPR014726 Ribosomal protein L2, domain 3 CO689_RS03135 9344b97b028745b7e25239267668fa91 277 SUPERFAMILY SSF50104 126 273 3.13E-60 T 28-03-2018 IPR008991 Translation protein SH3-like domain CO689_RS03135 9344b97b028745b7e25239267668fa91 277 Gene3D G3DSA:2.40.50.140 1 114 4.2E-48 T 28-03-2018 CO689_RS03135 9344b97b028745b7e25239267668fa91 277 PIRSF PIRSF002158 3 276 6.6E-101 T 28-03-2018 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CO689_RS03135 9344b97b028745b7e25239267668fa91 277 Gene3D G3DSA:2.30.30.30 119 195 9.8E-35 T 28-03-2018 IPR014722 Ribosomal protein L2 domain 2 CO689_RS03135 9344b97b028745b7e25239267668fa91 277 SUPERFAMILY SSF50249 2 125 2.43E-50 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CO689_RS03135 9344b97b028745b7e25239267668fa91 277 SMART SM01383 42 118 3.3E-46 T 28-03-2018 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CO689_RS03135 9344b97b028745b7e25239267668fa91 277 ProSitePatterns PS00467 Ribosomal protein L2 signature. 218 229 - T 28-03-2018 IPR022671 Ribosomal protein L2, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CO689_RS02025 3f023c383b0a12cb8be1a536a8dd0cab 400 TIGRFAM TIGR01537 portal_HK97: phage portal protein, HK97 family 39 368 3.8E-40 T 28-03-2018 IPR006427 Phage portal protein, HK97 CO689_RS02025 3f023c383b0a12cb8be1a536a8dd0cab 400 Pfam PF04860 Phage portal protein 45 362 3.0E-63 T 28-03-2018 IPR006944 Bacteriophage/Gene transfer agent portal protein CO689_RS12465 faad9ad1dfe9b6f1a6500d5322f8cf8c 239 TIGRFAM TIGR03532 DapD_Ac: 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase 7 237 7.9E-115 T 28-03-2018 IPR019873 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase, DapH GO:0009089|GO:0047200 KEGG: 00300+2.3.1.89|MetaCyc: PWY-2941 CO689_RS12465 faad9ad1dfe9b6f1a6500d5322f8cf8c 239 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 175 203 - T 28-03-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 CO689_RS12465 faad9ad1dfe9b6f1a6500d5322f8cf8c 239 Gene3D G3DSA:3.30.70.250 4 83 3.3E-33 T 28-03-2018 CO689_RS12465 faad9ad1dfe9b6f1a6500d5322f8cf8c 239 Hamap MF_01691 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase [dapH]. 2 236 43.673 T 28-03-2018 IPR019873 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase, DapH GO:0009089|GO:0047200 KEGG: 00300+2.3.1.89|MetaCyc: PWY-2941 CO689_RS12465 faad9ad1dfe9b6f1a6500d5322f8cf8c 239 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 122 157 8.2E-6 T 28-03-2018 IPR001451 Hexapeptide repeat CO689_RS12465 faad9ad1dfe9b6f1a6500d5322f8cf8c 239 Gene3D G3DSA:2.160.10.10 84 236 6.2E-43 T 28-03-2018 CO689_RS12465 faad9ad1dfe9b6f1a6500d5322f8cf8c 239 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 166 201 1.1E-10 T 28-03-2018 IPR001451 Hexapeptide repeat CO689_RS12465 faad9ad1dfe9b6f1a6500d5322f8cf8c 239 SUPERFAMILY SSF51161 88 224 2.5E-49 T 28-03-2018 IPR011004 Trimeric LpxA-like CO689_RS12465 faad9ad1dfe9b6f1a6500d5322f8cf8c 239 Pfam PF08503 Tetrahydrodipicolinate succinyltransferase N-terminal 5 88 1.2E-31 T 28-03-2018 IPR013710 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase, N-terminal GO:0047200 KEGG: 00300+2.3.1.89|MetaCyc: PWY-2941 CO689_RS02965 c2859fbcff1127607ec135d87916a500 406 Pfam PF01814 Hemerythrin HHE cation binding domain 101 217 1.0E-10 T 28-03-2018 IPR012312 Haemerythrin-like Reactome: R-HSA-390471|Reactome: R-HSA-8951664|Reactome: R-HSA-917937|Reactome: R-HSA-983168 CO689_RS02965 c2859fbcff1127607ec135d87916a500 406 SUPERFAMILY SSF55785 282 384 8.38E-7 T 28-03-2018 IPR000014 PAS domain CO689_RS02965 c2859fbcff1127607ec135d87916a500 406 Gene3D G3DSA:1.20.120.520 81 287 1.5E-35 T 28-03-2018 CO689_RS02965 c2859fbcff1127607ec135d87916a500 406 Pfam PF13596 PAS domain 283 390 2.3E-28 T 28-03-2018 CO689_RS02965 c2859fbcff1127607ec135d87916a500 406 Gene3D G3DSA:3.30.450.20 288 397 1.3E-8 T 28-03-2018 CO689_RS11720 a7834610f678896fa7cdb6fae2bea1f8 155 Hamap MF_01077 Ribosome maturation factor RimP [rimP]. 6 155 21.81 T 28-03-2018 IPR003728 Ribosome maturation factor RimP GO:0042274 CO689_RS11720 a7834610f678896fa7cdb6fae2bea1f8 155 Pfam PF17384 RimP C-terminal SH3 domain 90 150 9.5E-15 T 28-03-2018 IPR028998 Ribosome maturation factor RimP, C-terminal CO689_RS11720 a7834610f678896fa7cdb6fae2bea1f8 155 SUPERFAMILY SSF74942 84 153 5.49E-17 T 28-03-2018 IPR028998 Ribosome maturation factor RimP, C-terminal CO689_RS11720 a7834610f678896fa7cdb6fae2bea1f8 155 SUPERFAMILY SSF75420 2 83 2.62E-24 T 28-03-2018 IPR028989 Ribosome maturation factor RimP, N-terminal CO689_RS11720 a7834610f678896fa7cdb6fae2bea1f8 155 Gene3D G3DSA:3.30.300.70 1 80 1.7E-26 T 28-03-2018 IPR028989 Ribosome maturation factor RimP, N-terminal CO689_RS11720 a7834610f678896fa7cdb6fae2bea1f8 155 Pfam PF02576 RimP N-terminal domain 11 83 1.0E-25 T 28-03-2018 IPR028989 Ribosome maturation factor RimP, N-terminal CO689_RS11720 a7834610f678896fa7cdb6fae2bea1f8 155 Gene3D G3DSA:2.30.30.180 87 153 1.1E-17 T 28-03-2018 IPR028998 Ribosome maturation factor RimP, C-terminal CO689_RS08670 c9f375eb405149018c74fddf7663877a 139 Pfam PF00741 Gas vesicle protein 15 53 5.2E-16 T 28-03-2018 IPR000638 Gas vesicle protein GvpA GO:0005198|GO:0012506 CO689_RS08670 c9f375eb405149018c74fddf7663877a 139 ProSitePatterns PS00234 Gas vesicles protein GVPa signature 1. 16 30 - T 28-03-2018 IPR018493 Gas vesicle protein GvpA, conserved site GO:0005198|GO:0012506 CO689_RS09370 31413e2a320a1400fca2203ee909cf53 156 Gene3D G3DSA:2.40.280.10 12 130 1.1E-50 T 28-03-2018 IPR023620 Small protein B CO689_RS09370 31413e2a320a1400fca2203ee909cf53 156 ProDom PD004488 SSRA-BINDING RNA-BINDING SMPB SMALL B TMRNA-BINDING SSRA 3D-STRUCTURE HOMOLOG BINDING 13 135 3.0E-59 T 28-03-2018 IPR000037 SsrA-binding protein GO:0003723 CO689_RS09370 31413e2a320a1400fca2203ee909cf53 156 Pfam PF01668 SmpB protein 13 153 1.2E-61 T 28-03-2018 IPR000037 SsrA-binding protein GO:0003723 CO689_RS09370 31413e2a320a1400fca2203ee909cf53 156 TIGRFAM TIGR00086 smpB: SsrA-binding protein 12 153 9.7E-59 T 28-03-2018 IPR000037 SsrA-binding protein GO:0003723 CO689_RS09370 31413e2a320a1400fca2203ee909cf53 156 SUPERFAMILY SSF74982 5 135 1.24E-51 T 28-03-2018 IPR023620 Small protein B CO689_RS09370 31413e2a320a1400fca2203ee909cf53 156 ProSitePatterns PS01317 SsrA-binding protein. 30 42 - T 28-03-2018 IPR020081 SsrA-binding protein, conserved site CO689_RS09370 31413e2a320a1400fca2203ee909cf53 156 Hamap MF_00023 SsrA-binding protein [smpB]. 1 156 72.431 T 28-03-2018 IPR000037 SsrA-binding protein GO:0003723 CO689_RS13445 4e1703976adb1a085f75fbf9fa04d414 222 Pfam PF13181 Tetratricopeptide repeat 171 204 1.5E-4 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CO689_RS13445 4e1703976adb1a085f75fbf9fa04d414 222 Pfam PF13181 Tetratricopeptide repeat 101 133 1.3E-4 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CO689_RS13445 4e1703976adb1a085f75fbf9fa04d414 222 Gene3D G3DSA:1.20.58.280 58 86 3.0E-12 T 28-03-2018 CO689_RS13445 4e1703976adb1a085f75fbf9fa04d414 222 SMART SM00028 33 66 0.0033 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CO689_RS13445 4e1703976adb1a085f75fbf9fa04d414 222 SMART SM00028 101 134 0.86 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CO689_RS13445 4e1703976adb1a085f75fbf9fa04d414 222 SMART SM00028 170 204 0.0019 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CO689_RS13445 4e1703976adb1a085f75fbf9fa04d414 222 SMART SM00028 136 169 16.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CO689_RS13445 4e1703976adb1a085f75fbf9fa04d414 222 SMART SM00028 67 100 0.01 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CO689_RS13445 4e1703976adb1a085f75fbf9fa04d414 222 Pfam PF14559 Tetratricopeptide repeat 43 99 2.4E-9 T 28-03-2018 CO689_RS13445 4e1703976adb1a085f75fbf9fa04d414 222 Gene3D G3DSA:1.25.40.10 2 57 3.5E-12 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CO689_RS13445 4e1703976adb1a085f75fbf9fa04d414 222 Gene3D G3DSA:1.25.40.10 87 141 5.9E-11 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CO689_RS13445 4e1703976adb1a085f75fbf9fa04d414 222 Gene3D G3DSA:1.25.40.10 142 169 2.2E-7 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CO689_RS13445 4e1703976adb1a085f75fbf9fa04d414 222 SUPERFAMILY SSF48452 24 204 2.39E-32 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CO689_RS13445 4e1703976adb1a085f75fbf9fa04d414 222 Gene3D G3DSA:1.20.120.420 170 221 1.6E-7 T 28-03-2018 IPR027363 Methylthioribose-1-phosphate isomerase-like, N-terminal domain KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174 CO689_RS02080 089470501aee6fea07cf79fd118290d4 391 SUPERFAMILY SSF56349 63 374 1.68E-61 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CO689_RS02080 089470501aee6fea07cf79fd118290d4 391 Pfam PF00589 Phage integrase family 176 368 1.2E-28 T 28-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 CO689_RS02080 089470501aee6fea07cf79fd118290d4 391 Gene3D G3DSA:1.10.150.130 59 173 1.3E-17 T 28-03-2018 IPR023109 Integrase/recombinase, N-terminal CO689_RS02080 089470501aee6fea07cf79fd118290d4 391 Pfam PF14659 Phage integrase, N-terminal SAM-like domain 64 119 2.4E-6 T 28-03-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 CO689_RS02080 089470501aee6fea07cf79fd118290d4 391 Gene3D G3DSA:1.10.443.10 176 376 5.5E-39 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 CO689_RS02080 089470501aee6fea07cf79fd118290d4 391 Pfam PF14657 Arm DNA-binding domain 11 55 3.2E-8 T 28-03-2018 IPR028259 AP2-like integrase, N-terminal domain CO689_RS13225 0f3fabbef3d2214e8f4092888d89e68e 463 Pfam PF03129 Anticodon binding domain 372 459 1.7E-25 T 28-03-2018 IPR004154 Anticodon-binding CO689_RS13225 0f3fabbef3d2214e8f4092888d89e68e 463 Gene3D G3DSA:3.30.930.10 2 112 4.1E-22 T 28-03-2018 CO689_RS13225 0f3fabbef3d2214e8f4092888d89e68e 463 Gene3D G3DSA:3.30.930.10 123 236 3.1E-33 T 28-03-2018 CO689_RS13225 0f3fabbef3d2214e8f4092888d89e68e 463 Gene3D G3DSA:3.30.930.10 237 357 6.7E-43 T 28-03-2018 CO689_RS13225 0f3fabbef3d2214e8f4092888d89e68e 463 TIGRFAM TIGR00389 glyS_dimeric: glycine--tRNA ligase 4 237 5.1E-89 T 28-03-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CO689_RS13225 0f3fabbef3d2214e8f4092888d89e68e 463 SUPERFAMILY SSF55681 4 375 6.32E-128 T 28-03-2018 CO689_RS13225 0f3fabbef3d2214e8f4092888d89e68e 463 Hamap MF_00253_B Glycine--tRNA ligase [glyQS]. 2 462 51.537 T 28-03-2018 IPR022961 Glycine-tRNA ligase, bacterial GO:0004820 KEGG: 00970+6.1.1.14 CO689_RS13225 0f3fabbef3d2214e8f4092888d89e68e 463 Gene3D G3DSA:3.40.50.800 358 462 6.0E-30 T 28-03-2018 IPR004154 Anticodon-binding CO689_RS13225 0f3fabbef3d2214e8f4092888d89e68e 463 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 164 285 1.6E-10 T 28-03-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 CO689_RS13225 0f3fabbef3d2214e8f4092888d89e68e 463 PRINTS PR01043 Glycyl-tRNA synthetase signature 407 426 6.0E-53 T 28-03-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CO689_RS13225 0f3fabbef3d2214e8f4092888d89e68e 463 PRINTS PR01043 Glycyl-tRNA synthetase signature 326 338 6.0E-53 T 28-03-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CO689_RS13225 0f3fabbef3d2214e8f4092888d89e68e 463 PRINTS PR01043 Glycyl-tRNA synthetase signature 149 161 6.0E-53 T 28-03-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CO689_RS13225 0f3fabbef3d2214e8f4092888d89e68e 463 PRINTS PR01043 Glycyl-tRNA synthetase signature 219 229 6.0E-53 T 28-03-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CO689_RS13225 0f3fabbef3d2214e8f4092888d89e68e 463 PRINTS PR01043 Glycyl-tRNA synthetase signature 24 38 6.0E-53 T 28-03-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CO689_RS13225 0f3fabbef3d2214e8f4092888d89e68e 463 PRINTS PR01043 Glycyl-tRNA synthetase signature 170 187 6.0E-53 T 28-03-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CO689_RS13225 0f3fabbef3d2214e8f4092888d89e68e 463 PRINTS PR01043 Glycyl-tRNA synthetase signature 202 219 6.0E-53 T 28-03-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CO689_RS13225 0f3fabbef3d2214e8f4092888d89e68e 463 SUPERFAMILY SSF52954 359 462 2.27E-35 T 28-03-2018 IPR004154 Anticodon-binding CO689_RS05495 dfb86f13cf10fb47f5ec4f6d4d27c5e0 486 Gene3D G3DSA:1.20.1250.20 254 486 1.3E-30 T 28-03-2018 CO689_RS05495 dfb86f13cf10fb47f5ec4f6d4d27c5e0 486 PRINTS PR01036 Tetracycline resistance protein TetB signature 103 123 5.7E-11 T 28-03-2018 CO689_RS05495 dfb86f13cf10fb47f5ec4f6d4d27c5e0 486 PRINTS PR01036 Tetracycline resistance protein TetB signature 133 157 5.7E-11 T 28-03-2018 CO689_RS05495 dfb86f13cf10fb47f5ec4f6d4d27c5e0 486 PRINTS PR01036 Tetracycline resistance protein TetB signature 297 321 5.7E-11 T 28-03-2018 CO689_RS05495 dfb86f13cf10fb47f5ec4f6d4d27c5e0 486 PRINTS PR01036 Tetracycline resistance protein TetB signature 12 36 5.7E-11 T 28-03-2018 CO689_RS05495 dfb86f13cf10fb47f5ec4f6d4d27c5e0 486 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 8 427 1.6E-109 T 28-03-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 CO689_RS05495 dfb86f13cf10fb47f5ec4f6d4d27c5e0 486 SUPERFAMILY SSF103473 446 474 1.15E-70 T 28-03-2018 IPR020846 Major facilitator superfamily domain CO689_RS05495 dfb86f13cf10fb47f5ec4f6d4d27c5e0 486 SUPERFAMILY SSF103473 243 415 1.15E-70 T 28-03-2018 IPR020846 Major facilitator superfamily domain CO689_RS05495 dfb86f13cf10fb47f5ec4f6d4d27c5e0 486 SUPERFAMILY SSF103473 4 190 1.15E-70 T 28-03-2018 IPR020846 Major facilitator superfamily domain CO689_RS05495 dfb86f13cf10fb47f5ec4f6d4d27c5e0 486 Gene3D G3DSA:1.20.1250.20 2 191 3.6E-34 T 28-03-2018 CO689_RS05495 dfb86f13cf10fb47f5ec4f6d4d27c5e0 486 Pfam PF07690 Major Facilitator Superfamily 14 404 2.9E-54 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CO689_RS13120 1b8dacb2324292d71efa5bd6530540ee 109 Gene3D G3DSA:3.30.70.930 1 107 5.0E-31 T 28-03-2018 IPR029756 MTH1187/YkoF-like CO689_RS13120 1b8dacb2324292d71efa5bd6530540ee 109 SUPERFAMILY SSF89957 1 103 5.76E-28 T 28-03-2018 IPR029756 MTH1187/YkoF-like CO689_RS13120 1b8dacb2324292d71efa5bd6530540ee 109 Pfam PF01910 Thiamine-binding protein 4 99 4.6E-31 T 28-03-2018 IPR002767 Thiamine-binding protein CO689_RS13120 1b8dacb2324292d71efa5bd6530540ee 109 TIGRFAM TIGR00106 TIGR00106: uncharacterized protein, MTH1187 family 2 102 6.2E-33 T 28-03-2018 IPR002767 Thiamine-binding protein CO689_RS01770 991f0cb0b4ff674eb331454783b657a2 356 SUPERFAMILY SSF100879 240 341 7.06E-27 T 28-03-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 CO689_RS01770 991f0cb0b4ff674eb331454783b657a2 356 Gene3D G3DSA:3.30.1490.100 245 353 7.2E-31 T 28-03-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 CO689_RS01770 991f0cb0b4ff674eb331454783b657a2 356 SUPERFAMILY SSF56672 3 234 3.56E-90 T 28-03-2018 CO689_RS01770 991f0cb0b4ff674eb331454783b657a2 356 Gene3D G3DSA:1.10.150.20 173 244 1.9E-12 T 28-03-2018 CO689_RS01770 991f0cb0b4ff674eb331454783b657a2 356 Hamap MF_01113 DNA polymerase IV [dinB]. 3 352 37.723 T 28-03-2018 IPR022880 DNA polymerase IV GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5655862|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210 CO689_RS01770 991f0cb0b4ff674eb331454783b657a2 356 Pfam PF11799 impB/mucB/samB family C-terminal domain 236 345 3.1E-22 T 28-03-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 CO689_RS01770 991f0cb0b4ff674eb331454783b657a2 356 Gene3D G3DSA:3.30.70.270 121 172 6.8E-20 T 28-03-2018 CO689_RS01770 991f0cb0b4ff674eb331454783b657a2 356 Gene3D G3DSA:3.30.70.270 43 120 9.0E-27 T 28-03-2018 CO689_RS01770 991f0cb0b4ff674eb331454783b657a2 356 Pfam PF00817 impB/mucB/samB family 9 155 1.3E-52 T 28-03-2018 IPR001126 UmuC domain GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 CO689_RS05655 a72077593d29ae6e1b96cd284ff010e5 346 SUPERFAMILY SSF52518 4 218 2.25E-61 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CO689_RS05655 a72077593d29ae6e1b96cd284ff010e5 346 Pfam PF02779 Transketolase, pyrimidine binding domain 6 194 3.8E-46 T 28-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain CO689_RS05655 a72077593d29ae6e1b96cd284ff010e5 346 Gene3D G3DSA:3.40.50.970 3 208 3.0E-61 T 28-03-2018 CO689_RS05655 a72077593d29ae6e1b96cd284ff010e5 346 Pfam PF02780 Transketolase, C-terminal domain 208 330 3.1E-40 T 28-03-2018 IPR033248 Transketolase, C-terminal domain CO689_RS05655 a72077593d29ae6e1b96cd284ff010e5 346 Gene3D G3DSA:3.40.50.920 209 339 9.4E-39 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CO689_RS05655 a72077593d29ae6e1b96cd284ff010e5 346 SMART SM00861 7 194 3.4E-56 T 28-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain CO689_RS05655 a72077593d29ae6e1b96cd284ff010e5 346 SUPERFAMILY SSF52922 202 338 3.93E-40 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CO689_RS08020 6e0b01da41469e720b18545c2e479305 140 Gene3D G3DSA:1.10.10.250 72 140 1.5E-26 T 28-03-2018 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 CO689_RS08020 6e0b01da41469e720b18545c2e479305 140 Gene3D G3DSA:3.30.1550.10 3 71 2.1E-36 T 28-03-2018 IPR020784 Ribosomal protein L11, N-terminal CO689_RS08020 6e0b01da41469e720b18545c2e479305 140 SUPERFAMILY SSF54747 3 72 3.14E-30 T 28-03-2018 IPR020784 Ribosomal protein L11, N-terminal CO689_RS08020 6e0b01da41469e720b18545c2e479305 140 Pfam PF00298 Ribosomal protein L11, RNA binding domain 71 139 3.7E-27 T 28-03-2018 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 CO689_RS08020 6e0b01da41469e720b18545c2e479305 140 SMART SM00649 9 140 3.1E-89 T 28-03-2018 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 CO689_RS08020 6e0b01da41469e720b18545c2e479305 140 ProDom PD001367 RIBOSOMAL RIBONUCLEOPROTEIN L11 RRNA-BINDING RNA-BINDING METHYLATION 50S L11 BACTERIAL CHLOROPLAST 36 73 1.0E-16 T 28-03-2018 CO689_RS08020 6e0b01da41469e720b18545c2e479305 140 Hamap MF_00736 50S ribosomal protein L11 [rplK]. 5 140 31.603 T 28-03-2018 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 CO689_RS08020 6e0b01da41469e720b18545c2e479305 140 Pfam PF03946 Ribosomal protein L11, N-terminal domain 9 66 4.8E-31 T 28-03-2018 IPR020784 Ribosomal protein L11, N-terminal CO689_RS08020 6e0b01da41469e720b18545c2e479305 140 SUPERFAMILY SSF46906 67 140 7.06E-29 T 28-03-2018 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 CO689_RS08020 6e0b01da41469e720b18545c2e479305 140 ProSitePatterns PS00359 Ribosomal protein L11 signature. 126 140 - T 28-03-2018 IPR020785 Ribosomal protein L11, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CO689_RS08020 6e0b01da41469e720b18545c2e479305 140 TIGRFAM TIGR01632 L11_bact: ribosomal protein uL11 3 140 8.4E-66 T 28-03-2018 IPR006519 Ribosomal protein L11, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CO689_RS12045 3becad1f50ff69eb57157cfae37767de 121 SUPERFAMILY SSF46955 13 96 4.03E-19 T 28-03-2018 IPR009061 Putative DNA-binding domain CO689_RS12045 3becad1f50ff69eb57157cfae37767de 121 SMART SM00422 13 81 2.6E-24 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CO689_RS12045 3becad1f50ff69eb57157cfae37767de 121 Gene3D G3DSA:1.10.1660.10 2 111 3.0E-23 T 28-03-2018 CO689_RS12045 3becad1f50ff69eb57157cfae37767de 121 Pfam PF13411 MerR HTH family regulatory protein 13 78 8.4E-19 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CO689_RS06290 4639615339584f1cc2f7aa4b3a32fe70 445 Gene3D G3DSA:3.60.15.10 1 262 3.9E-43 T 28-03-2018 IPR001279 Metallo-beta-lactamase CO689_RS06290 4639615339584f1cc2f7aa4b3a32fe70 445 SUPERFAMILY SSF52821 239 340 3.01E-9 T 28-03-2018 IPR001763 Rhodanese-like domain CO689_RS06290 4639615339584f1cc2f7aa4b3a32fe70 445 SMART SM00849 12 195 3.9E-28 T 28-03-2018 IPR001279 Metallo-beta-lactamase CO689_RS06290 4639615339584f1cc2f7aa4b3a32fe70 445 SMART SM00450 350 445 1.7E-13 T 28-03-2018 IPR001763 Rhodanese-like domain CO689_RS06290 4639615339584f1cc2f7aa4b3a32fe70 445 Pfam PF00753 Metallo-beta-lactamase superfamily 13 177 6.7E-10 T 28-03-2018 IPR001279 Metallo-beta-lactamase CO689_RS06290 4639615339584f1cc2f7aa4b3a32fe70 445 Pfam PF00581 Rhodanese-like domain 361 438 4.8E-9 T 28-03-2018 IPR001763 Rhodanese-like domain CO689_RS06290 4639615339584f1cc2f7aa4b3a32fe70 445 Gene3D G3DSA:3.40.250.10 346 442 2.6E-18 T 28-03-2018 IPR001763 Rhodanese-like domain CO689_RS06290 4639615339584f1cc2f7aa4b3a32fe70 445 Gene3D G3DSA:3.40.250.10 263 343 7.4E-6 T 28-03-2018 IPR001763 Rhodanese-like domain CO689_RS06290 4639615339584f1cc2f7aa4b3a32fe70 445 SUPERFAMILY SSF52821 359 438 1.83E-20 T 28-03-2018 IPR001763 Rhodanese-like domain CO689_RS06290 4639615339584f1cc2f7aa4b3a32fe70 445 SUPERFAMILY SSF56281 1 256 3.78E-49 T 28-03-2018 IPR001279 Metallo-beta-lactamase CO689_RS08985 02984b2e94bbed73db3f65afaafc5c77 133 Hamap MF_00128 Protein NrdI [nrdI]. 1 125 26.875 T 28-03-2018 IPR020852 Ribonucleotide reductase, class Ib, NrdI, bacterial CO689_RS08985 02984b2e94bbed73db3f65afaafc5c77 133 Gene3D G3DSA:3.40.50.360 1 124 6.9E-20 T 28-03-2018 IPR029039 Flavoprotein-like domain CO689_RS08985 02984b2e94bbed73db3f65afaafc5c77 133 TIGRFAM TIGR00333 nrdI: nrdI protein 3 120 1.9E-34 T 28-03-2018 IPR004465 Ribonucleotide reductase Class Ib, NrdI CO689_RS08985 02984b2e94bbed73db3f65afaafc5c77 133 Pfam PF07972 NrdI Flavodoxin like 3 115 8.9E-34 T 28-03-2018 IPR004465 Ribonucleotide reductase Class Ib, NrdI CO689_RS08985 02984b2e94bbed73db3f65afaafc5c77 133 PIRSF PIRSF005087 1 129 4.5E-41 T 28-03-2018 IPR004465 Ribonucleotide reductase Class Ib, NrdI CO689_RS08985 02984b2e94bbed73db3f65afaafc5c77 133 SUPERFAMILY SSF52218 2 124 7.68E-23 T 28-03-2018 IPR029039 Flavoprotein-like domain CO689_RS06530 63d83ea75fe6182e342aa73a86a4f746 657 Pfam PF02378 Phosphotransferase system, EIIC 132 407 6.6E-25 T 28-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 CO689_RS06530 63d83ea75fe6182e342aa73a86a4f746 657 SUPERFAMILY SSF52794 2 103 3.14E-38 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 CO689_RS06530 63d83ea75fe6182e342aa73a86a4f746 657 TIGRFAM TIGR00829 FRU: PTS system, Fru family, IIB component 5 86 4.9E-33 T 28-03-2018 IPR003353 Phosphotransferase system, fructose-specific IIB subunit GO:0009401|GO:0022877 KEGG: 00051+2.7.1.202|KEGG: 00230+2.7.1.20|MetaCyc: PWY-6619 CO689_RS06530 63d83ea75fe6182e342aa73a86a4f746 657 Gene3D G3DSA:3.40.50.2300 2 98 2.6E-39 T 28-03-2018 CO689_RS06530 63d83ea75fe6182e342aa73a86a4f746 657 ProSitePatterns PS00372 PTS EIIA domains phosphorylation site signature 2. 560 576 - T 28-03-2018 IPR002178 PTS EIIA type-2 domain CO689_RS06530 63d83ea75fe6182e342aa73a86a4f746 657 TIGRFAM TIGR00848 fruA: PTS system, fructose subfamily, IIA component 514 641 1.4E-41 T 28-03-2018 IPR004715 Phosphotransferase system, IIA component fructose subfamily GO:0008982|GO:0009401|GO:0016021 CO689_RS06530 63d83ea75fe6182e342aa73a86a4f746 657 TIGRFAM TIGR01427 PTS_IIC_fructo: PTS system, Fru family, IIC component 116 458 2.6E-95 T 28-03-2018 IPR006327 Phosphotransferase system, fructose IIC component GO:0005351|GO:0008982|GO:0009401|GO:0016021 CO689_RS06530 63d83ea75fe6182e342aa73a86a4f746 657 Gene3D G3DSA:3.40.930.10 509 656 3.2E-37 T 28-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 CO689_RS06530 63d83ea75fe6182e342aa73a86a4f746 657 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 514 655 1.5E-36 T 28-03-2018 IPR002178 PTS EIIA type-2 domain CO689_RS06530 63d83ea75fe6182e342aa73a86a4f746 657 SUPERFAMILY SSF55804 514 655 8.37E-37 T 28-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 CO689_RS06530 63d83ea75fe6182e342aa73a86a4f746 657 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 5 94 5.7E-17 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 CO689_RS02700 c249c48ed2190110feaab092d66b2d8c 601 Hamap MF_00164 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] [glmS]. 1 601 39.05 T 28-03-2018 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 CO689_RS02700 c249c48ed2190110feaab092d66b2d8c 601 TIGRFAM TIGR01135 glmS: glutamine-fructose-6-phosphate transaminase (isomerizing) 2 601 1.3E-231 T 28-03-2018 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 CO689_RS02700 c249c48ed2190110feaab092d66b2d8c 601 Gene3D G3DSA:3.40.50.10490 240 453 4.7E-62 T 28-03-2018 CO689_RS02700 c249c48ed2190110feaab092d66b2d8c 601 SUPERFAMILY SSF56235 2 235 4.72E-69 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CO689_RS02700 c249c48ed2190110feaab092d66b2d8c 601 Gene3D G3DSA:3.40.50.10490 454 599 4.9E-40 T 28-03-2018 CO689_RS02700 c249c48ed2190110feaab092d66b2d8c 601 Gene3D G3DSA:3.60.20.10 2 239 7.2E-65 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CO689_RS02700 c249c48ed2190110feaab092d66b2d8c 601 Pfam PF13522 Glutamine amidotransferase domain 63 193 1.2E-21 T 28-03-2018 CO689_RS02700 c249c48ed2190110feaab092d66b2d8c 601 Pfam PF01380 SIS domain 458 583 2.3E-17 T 28-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 CO689_RS02700 c249c48ed2190110feaab092d66b2d8c 601 Pfam PF01380 SIS domain 289 412 1.9E-32 T 28-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 CO689_RS02700 c249c48ed2190110feaab092d66b2d8c 601 SUPERFAMILY SSF53697 245 601 9.28E-97 T 28-03-2018 CO689_RS10975 348541d64aa95ce5b9c067518f2a5fbb 303 Hamap MF_00154 Protoheme IX farnesyltransferase [cyoE]. 15 299 16.778 T 28-03-2018 IPR006369 Protohaem IX farnesyltransferase GO:0008495|GO:0016021|GO:0048034 Reactome: R-HSA-189451 CO689_RS10975 348541d64aa95ce5b9c067518f2a5fbb 303 Pfam PF01040 UbiA prenyltransferase family 33 284 2.2E-55 T 28-03-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 CO689_RS10975 348541d64aa95ce5b9c067518f2a5fbb 303 TIGRFAM TIGR01473 cyoE_ctaB: protoheme IX farnesyltransferase 18 296 7.8E-90 T 28-03-2018 IPR006369 Protohaem IX farnesyltransferase GO:0008495|GO:0016021|GO:0048034 Reactome: R-HSA-189451 CO689_RS01880 de8d2cb607e42a6c76662734ba97b854 183 Gene3D G3DSA:3.40.50.850 1 183 3.4E-44 T 28-03-2018 CO689_RS01880 de8d2cb607e42a6c76662734ba97b854 183 SUPERFAMILY SSF52499 2 180 5.49E-48 T 28-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CO689_RS01880 de8d2cb607e42a6c76662734ba97b854 183 Pfam PF00857 Isochorismatase family 5 177 1.1E-33 T 28-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CO689_RS12865 bac9bb19918c9dfe4364a6b220b564f2 241 Gene3D G3DSA:3.40.50.2300 2 128 6.9E-39 T 28-03-2018 CO689_RS12865 bac9bb19918c9dfe4364a6b220b564f2 241 Pfam PF00486 Transcriptional regulatory protein, C terminal 154 231 1.9E-27 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CO689_RS12865 bac9bb19918c9dfe4364a6b220b564f2 241 SUPERFAMILY SSF52172 2 188 3.37E-42 T 28-03-2018 IPR011006 CheY-like superfamily CO689_RS12865 bac9bb19918c9dfe4364a6b220b564f2 241 Gene3D G3DSA:1.10.10.10 129 238 3.6E-34 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS12865 bac9bb19918c9dfe4364a6b220b564f2 241 SMART SM00448 3 113 8.6E-47 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CO689_RS12865 bac9bb19918c9dfe4364a6b220b564f2 241 Pfam PF00072 Response regulator receiver domain 5 113 6.6E-31 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CO689_RS12865 bac9bb19918c9dfe4364a6b220b564f2 241 SMART SM00862 154 231 8.3E-26 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CO689_RS02660 356ce7a2213af4ede9a5c029c1914686 244 Pfam PF02754 Cysteine-rich domain 3 84 6.2E-15 T 28-03-2018 IPR004017 Cysteine-rich domain CO689_RS02660 356ce7a2213af4ede9a5c029c1914686 244 Pfam PF02754 Cysteine-rich domain 132 215 2.9E-15 T 28-03-2018 IPR004017 Cysteine-rich domain CO689_RS12815 46f17d607bf59e8838f0ebaad69158be 396 SUPERFAMILY SSF50249 93 177 6.32E-16 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CO689_RS12815 46f17d607bf59e8838f0ebaad69158be 396 PRINTS PR00681 Ribosomal protein S1 signature 111 127 3.6E-44 T 28-03-2018 CO689_RS12815 46f17d607bf59e8838f0ebaad69158be 396 PRINTS PR00681 Ribosomal protein S1 signature 157 177 3.6E-44 T 28-03-2018 CO689_RS12815 46f17d607bf59e8838f0ebaad69158be 396 PRINTS PR00681 Ribosomal protein S1 signature 128 145 3.6E-44 T 28-03-2018 CO689_RS12815 46f17d607bf59e8838f0ebaad69158be 396 PRINTS PR00681 Ribosomal protein S1 signature 331 349 3.6E-44 T 28-03-2018 CO689_RS12815 46f17d607bf59e8838f0ebaad69158be 396 PRINTS PR00681 Ribosomal protein S1 signature 16 34 3.6E-44 T 28-03-2018 CO689_RS12815 46f17d607bf59e8838f0ebaad69158be 396 PRINTS PR00681 Ribosomal protein S1 signature 292 311 3.6E-44 T 28-03-2018 CO689_RS12815 46f17d607bf59e8838f0ebaad69158be 396 PRINTS PR00681 Ribosomal protein S1 signature 214 235 3.6E-44 T 28-03-2018 CO689_RS12815 46f17d607bf59e8838f0ebaad69158be 396 SUPERFAMILY SSF50249 10 116 4.58E-21 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CO689_RS12815 46f17d607bf59e8838f0ebaad69158be 396 SUPERFAMILY SSF50249 192 275 2.73E-25 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CO689_RS12815 46f17d607bf59e8838f0ebaad69158be 396 Gene3D G3DSA:2.40.50.140 184 267 1.2E-26 T 28-03-2018 CO689_RS12815 46f17d607bf59e8838f0ebaad69158be 396 Gene3D G3DSA:2.40.50.140 97 179 6.5E-15 T 28-03-2018 CO689_RS12815 46f17d607bf59e8838f0ebaad69158be 396 Gene3D G3DSA:2.40.50.140 6 96 5.1E-19 T 28-03-2018 CO689_RS12815 46f17d607bf59e8838f0ebaad69158be 396 SUPERFAMILY SSF50249 262 371 1.86E-24 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CO689_RS12815 46f17d607bf59e8838f0ebaad69158be 396 Pfam PF00575 S1 RNA binding domain 13 79 7.1E-14 T 28-03-2018 IPR003029 S1 domain GO:0003676 CO689_RS12815 46f17d607bf59e8838f0ebaad69158be 396 Pfam PF00575 S1 RNA binding domain 191 262 9.9E-25 T 28-03-2018 IPR003029 S1 domain GO:0003676 CO689_RS12815 46f17d607bf59e8838f0ebaad69158be 396 Pfam PF00575 S1 RNA binding domain 104 173 2.8E-12 T 28-03-2018 IPR003029 S1 domain GO:0003676 CO689_RS12815 46f17d607bf59e8838f0ebaad69158be 396 Pfam PF00575 S1 RNA binding domain 278 348 2.8E-22 T 28-03-2018 IPR003029 S1 domain GO:0003676 CO689_RS12815 46f17d607bf59e8838f0ebaad69158be 396 Gene3D G3DSA:2.40.50.140 279 381 2.5E-25 T 28-03-2018 CO689_RS12815 46f17d607bf59e8838f0ebaad69158be 396 SMART SM00316 277 348 1.6E-26 T 28-03-2018 IPR022967 RNA-binding domain, S1 CO689_RS12815 46f17d607bf59e8838f0ebaad69158be 396 SMART SM00316 106 173 1.1E-11 T 28-03-2018 IPR022967 RNA-binding domain, S1 CO689_RS12815 46f17d607bf59e8838f0ebaad69158be 396 SMART SM00316 192 262 1.0E-25 T 28-03-2018 IPR022967 RNA-binding domain, S1 CO689_RS12815 46f17d607bf59e8838f0ebaad69158be 396 SMART SM00316 14 90 2.6E-16 T 28-03-2018 IPR022967 RNA-binding domain, S1 CO689_RS00930 c17586fae804428e4916171130890011 203 SUPERFAMILY SSF69593 5 198 9.81E-41 T 28-03-2018 CO689_RS00930 c17586fae804428e4916171130890011 203 SMART SM00563 34 145 1.5E-27 T 28-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 CO689_RS00930 c17586fae804428e4916171130890011 203 TIGRFAM TIGR00530 AGP_acyltrn: 1-acylglycerol-3-phosphate O-acyltransferases 20 142 8.6E-32 T 28-03-2018 IPR004552 1-acyl-sn-glycerol-3-phosphate acyltransferase GO:0003841|GO:0008654|GO:0016020 KEGG: 00561+2.3.1.51|KEGG: 00564+2.3.1.51|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-6453|MetaCyc: PWY-7411|MetaCyc: PWY-7417|MetaCyc: PWY-7587|MetaCyc: PWY-7589|MetaCyc: PWY-7782|Reactome: R-HSA-1483166 CO689_RS00930 c17586fae804428e4916171130890011 203 Gene3D G3DSA:3.40.1130.10 1 203 8.6E-39 T 28-03-2018 CO689_RS00930 c17586fae804428e4916171130890011 203 Pfam PF01553 Acyltransferase 20 142 1.0E-23 T 28-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 CO689_RS10020 f19c707cb80a93d30c9e7f6148bf79a6 198 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 31 46 2.1E-19 T 28-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 CO689_RS10020 f19c707cb80a93d30c9e7f6148bf79a6 198 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 99 114 2.1E-19 T 28-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 CO689_RS10020 f19c707cb80a93d30c9e7f6148bf79a6 198 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 57 69 2.1E-19 T 28-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 CO689_RS10020 f19c707cb80a93d30c9e7f6148bf79a6 198 Pfam PF00160 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD 18 194 2.2E-47 T 28-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 CO689_RS10020 f19c707cb80a93d30c9e7f6148bf79a6 198 SUPERFAMILY SSF50891 148 195 1.01E-58 T 28-03-2018 IPR029000 Cyclophilin-like domain CO689_RS10020 f19c707cb80a93d30c9e7f6148bf79a6 198 SUPERFAMILY SSF50891 18 119 1.01E-58 T 28-03-2018 IPR029000 Cyclophilin-like domain CO689_RS10020 f19c707cb80a93d30c9e7f6148bf79a6 198 Gene3D G3DSA:2.40.100.10 2 198 1.5E-65 T 28-03-2018 IPR029000 Cyclophilin-like domain CO689_RS10020 f19c707cb80a93d30c9e7f6148bf79a6 198 PIRSF PIRSF001467 146 198 1.5E-9 T 28-03-2018 IPR024936 Cyclophilin-type peptidyl-prolyl cis-trans isomerase GO:0003755 CO689_RS10020 f19c707cb80a93d30c9e7f6148bf79a6 198 PIRSF PIRSF001467 6 128 8.8E-43 T 28-03-2018 IPR024936 Cyclophilin-type peptidyl-prolyl cis-trans isomerase GO:0003755 CO689_RS05275 1a6b5dd0cf5e295305ffd3364295e7a4 957 SMART SM00490 468 549 6.8E-16 T 28-03-2018 IPR001650 Helicase, C-terminal CO689_RS05275 1a6b5dd0cf5e295305ffd3364295e7a4 957 Gene3D G3DSA:3.30.870.10 28 212 1.0E-19 T 28-03-2018 CO689_RS05275 1a6b5dd0cf5e295305ffd3364295e7a4 957 Pfam PF13091 PLD-like domain 47 177 6.6E-17 T 28-03-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 CO689_RS05275 1a6b5dd0cf5e295305ffd3364295e7a4 957 SMART SM00487 221 410 1.0E-8 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CO689_RS05275 1a6b5dd0cf5e295305ffd3364295e7a4 957 Pfam PF00271 Helicase conserved C-terminal domain 456 547 3.3E-15 T 28-03-2018 IPR001650 Helicase, C-terminal CO689_RS05275 1a6b5dd0cf5e295305ffd3364295e7a4 957 Pfam PF04851 Type III restriction enzyme, res subunit 223 375 1.6E-33 T 28-03-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 CO689_RS05275 1a6b5dd0cf5e295305ffd3364295e7a4 957 SUPERFAMILY SSF52540 270 568 3.38E-44 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CO689_RS05275 1a6b5dd0cf5e295305ffd3364295e7a4 957 Gene3D G3DSA:3.40.50.300 421 816 1.4E-27 T 28-03-2018 CO689_RS05275 1a6b5dd0cf5e295305ffd3364295e7a4 957 Gene3D G3DSA:3.40.50.300 213 392 1.3E-21 T 28-03-2018 CO689_RS05275 1a6b5dd0cf5e295305ffd3364295e7a4 957 Pfam PF11907 Domain of unknown function (DUF3427) 688 954 4.4E-79 T 28-03-2018 IPR021835 Protein of unknown function DUF3427 CO689_RS05275 1a6b5dd0cf5e295305ffd3364295e7a4 957 SUPERFAMILY SSF56024 36 184 2.24E-17 T 28-03-2018 CO689_RS01045 d047c66bffe086277010a458c74a5d9d 471 TIGRFAM TIGR01887 dipeptidaselike: putative dipeptidase 10 464 1.1E-175 T 28-03-2018 IPR010964 Peptidase M20A, peptidase V-related GO:0008270|GO:0016805 CO689_RS01045 d047c66bffe086277010a458c74a5d9d 471 Gene3D G3DSA:3.40.630.10 1 206 1.8E-34 T 28-03-2018 CO689_RS01045 d047c66bffe086277010a458c74a5d9d 471 SUPERFAMILY SSF55031 183 380 3.46E-47 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain CO689_RS01045 d047c66bffe086277010a458c74a5d9d 471 Gene3D G3DSA:3.30.70.360 207 286 1.7E-6 T 28-03-2018 CO689_RS01045 d047c66bffe086277010a458c74a5d9d 471 SUPERFAMILY SSF53187 3 183 4.0E-61 T 28-03-2018 CO689_RS01045 d047c66bffe086277010a458c74a5d9d 471 SUPERFAMILY SSF53187 386 468 4.0E-61 T 28-03-2018 CO689_RS01045 d047c66bffe086277010a458c74a5d9d 471 Pfam PF01546 Peptidase family M20/M25/M40 83 465 9.8E-27 T 28-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CO689_RS01045 d047c66bffe086277010a458c74a5d9d 471 Gene3D G3DSA:3.30.70.360 287 375 2.9E-22 T 28-03-2018 CO689_RS02720 b8367477aefa54a3ff830c4983c2fc16 367 PRINTS PR00084 Mannitol dehydrogenase signature 3 13 2.2E-11 T 28-03-2018 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0008152|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 CO689_RS02720 b8367477aefa54a3ff830c4983c2fc16 367 PRINTS PR00084 Mannitol dehydrogenase signature 142 155 2.2E-11 T 28-03-2018 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0008152|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 CO689_RS02720 b8367477aefa54a3ff830c4983c2fc16 367 PRINTS PR00084 Mannitol dehydrogenase signature 160 175 2.2E-11 T 28-03-2018 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0008152|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 CO689_RS02720 b8367477aefa54a3ff830c4983c2fc16 367 Gene3D G3DSA:3.40.50.720 78 185 6.8E-20 T 28-03-2018 CO689_RS02720 b8367477aefa54a3ff830c4983c2fc16 367 Gene3D G3DSA:3.40.50.720 1 77 2.2E-8 T 28-03-2018 CO689_RS02720 b8367477aefa54a3ff830c4983c2fc16 367 Hamap MF_00196 Mannitol-1-phosphate 5-dehydrogenase [mtlD]. 1 366 37.503 T 28-03-2018 IPR023028 Mannitol-1-phosphate 5-dehydrogenase GO:0008926|GO:0019594|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 CO689_RS02720 b8367477aefa54a3ff830c4983c2fc16 367 ProSitePatterns PS00974 Mannitol dehydrogenases signature. 142 154 - T 28-03-2018 IPR023027 Mannitol dehydrogenase, conserved site GO:0019594|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 CO689_RS02720 b8367477aefa54a3ff830c4983c2fc16 367 SUPERFAMILY SSF51735 1 183 2.32E-38 T 28-03-2018 IPR016040 NAD(P)-binding domain CO689_RS02720 b8367477aefa54a3ff830c4983c2fc16 367 SUPERFAMILY SSF48179 192 358 1.19E-39 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CO689_RS02720 b8367477aefa54a3ff830c4983c2fc16 367 Pfam PF01232 Mannitol dehydrogenase Rossmann domain 1 119 2.2E-21 T 28-03-2018 IPR013131 Mannitol dehydrogenase, N-terminal GO:0016491|GO:0055114 CO689_RS02720 b8367477aefa54a3ff830c4983c2fc16 367 Gene3D G3DSA:1.10.1040.10 191 366 4.7E-38 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CO689_RS02720 b8367477aefa54a3ff830c4983c2fc16 367 Pfam PF08125 Mannitol dehydrogenase C-terminal domain 141 354 7.1E-46 T 28-03-2018 IPR013118 Mannitol dehydrogenase, C-terminal GO:0016491|GO:0050662|GO:0055114 CO689_RS04150 d261cfe67aa8b90e9af283dfd17f3d08 209 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 34 199 1.5E-22 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CO689_RS04150 d261cfe67aa8b90e9af283dfd17f3d08 209 Gene3D G3DSA:1.10.3720.10 2 207 8.1E-27 T 28-03-2018 CO689_RS04150 d261cfe67aa8b90e9af283dfd17f3d08 209 SUPERFAMILY SSF161098 11 196 4.19E-36 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CO689_RS01790 e6121088cf14966ece730a4e8f8d66cc 485 ProSitePatterns PS00571 Amidases signature. 152 183 - T 28-03-2018 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921|Reactome: R-HSA-2142753 CO689_RS01790 e6121088cf14966ece730a4e8f8d66cc 485 TIGRFAM TIGR00132 gatA: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, A subunit 12 476 4.5E-197 T 28-03-2018 IPR004412 Glutamyl-tRNA(Gln) amidotransferase A subunit GO:0006412|GO:0030956|GO:0050567 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CO689_RS01790 e6121088cf14966ece730a4e8f8d66cc 485 Gene3D G3DSA:3.90.1300.10 1 485 4.0E-169 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CO689_RS01790 e6121088cf14966ece730a4e8f8d66cc 485 SUPERFAMILY SSF75304 1 480 3.92E-159 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CO689_RS01790 e6121088cf14966ece730a4e8f8d66cc 485 Hamap MF_00120 Glutamyl-tRNA(Gln) amidotransferase subunit A [gatA]. 11 477 91.911 T 28-03-2018 IPR004412 Glutamyl-tRNA(Gln) amidotransferase A subunit GO:0006412|GO:0030956|GO:0050567 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CO689_RS01790 e6121088cf14966ece730a4e8f8d66cc 485 Pfam PF01425 Amidase 24 465 1.7E-158 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CO689_RS04925 177d51a74d62965f901018148955fcf3 383 SUPERFAMILY SSF53901 4 258 1.33E-54 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CO689_RS04925 177d51a74d62965f901018148955fcf3 383 Gene3D G3DSA:3.40.47.10 1 253 1.4E-45 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CO689_RS04925 177d51a74d62965f901018148955fcf3 383 Gene3D G3DSA:3.40.47.10 254 383 9.0E-22 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CO689_RS04925 177d51a74d62965f901018148955fcf3 383 Pfam PF02803 Thiolase, C-terminal domain 264 380 5.5E-30 T 28-03-2018 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 CO689_RS04925 177d51a74d62965f901018148955fcf3 383 PIRSF PIRSF000429 1 382 1.8E-110 T 28-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 CO689_RS04925 177d51a74d62965f901018148955fcf3 383 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 6 379 1.7E-114 T 28-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 CO689_RS04925 177d51a74d62965f901018148955fcf3 383 Pfam PF00108 Thiolase, N-terminal domain 5 251 5.9E-56 T 28-03-2018 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 CO689_RS04925 177d51a74d62965f901018148955fcf3 383 SUPERFAMILY SSF53901 264 379 1.03E-29 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CO689_RS04925 177d51a74d62965f901018148955fcf3 383 ProSitePatterns PS00737 Thiolases signature 2. 327 343 - T 28-03-2018 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 CO689_RS12690 12e2e89d6fb701a44dd80e84be2ba67a 208 PIRSF PIRSF037785 23 207 3.8E-80 T 28-03-2018 IPR004612 Holliday junction resolvase RecU GO:0005737|GO:0006281|GO:0006310 CO689_RS12690 12e2e89d6fb701a44dd80e84be2ba67a 208 Hamap MF_00130 Holliday junction resolvase RecU [recU]. 1 208 101.283 T 28-03-2018 IPR004612 Holliday junction resolvase RecU GO:0005737|GO:0006281|GO:0006310 CO689_RS12690 12e2e89d6fb701a44dd80e84be2ba67a 208 Gene3D G3DSA:3.40.1350.10 33 199 1.9E-63 T 28-03-2018 CO689_RS12690 12e2e89d6fb701a44dd80e84be2ba67a 208 SUPERFAMILY SSF52980 34 200 4.02E-66 T 28-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 CO689_RS12690 12e2e89d6fb701a44dd80e84be2ba67a 208 Pfam PF03838 Recombination protein U 32 197 4.0E-66 T 28-03-2018 IPR004612 Holliday junction resolvase RecU GO:0005737|GO:0006281|GO:0006310 CO689_RS12690 12e2e89d6fb701a44dd80e84be2ba67a 208 TIGRFAM TIGR00648 recU: recombination protein U 31 199 3.5E-83 T 28-03-2018 IPR004612 Holliday junction resolvase RecU GO:0005737|GO:0006281|GO:0006310 CO689_RS11810 c5d40f1d573de16446b6b379e8a7272b 557 Gene3D G3DSA:3.60.15.10 3 450 9.8E-54 T 28-03-2018 IPR001279 Metallo-beta-lactamase CO689_RS11810 c5d40f1d573de16446b6b379e8a7272b 557 Pfam PF00753 Metallo-beta-lactamase superfamily 23 118 5.5E-6 T 28-03-2018 IPR001279 Metallo-beta-lactamase CO689_RS11810 c5d40f1d573de16446b6b379e8a7272b 557 PIRSF PIRSF004803 2 557 1.2E-196 T 28-03-2018 IPR030854 Ribonuclease J, bacteria GO:0004521|GO:0004534|GO:0006396|GO:0008270|GO:0090501 CO689_RS11810 c5d40f1d573de16446b6b379e8a7272b 557 SUPERFAMILY SSF56281 11 425 6.21E-73 T 28-03-2018 IPR001279 Metallo-beta-lactamase CO689_RS11810 c5d40f1d573de16446b6b379e8a7272b 557 SMART SM00849 23 217 5.0E-22 T 28-03-2018 IPR001279 Metallo-beta-lactamase CO689_RS11810 c5d40f1d573de16446b6b379e8a7272b 557 Pfam PF07521 Zn-dependent metallo-hydrolase RNA specificity domain 358 409 7.7E-10 T 28-03-2018 IPR011108 Zn-dependent metallo-hydrolase, RNA specificity domain CO689_RS11810 c5d40f1d573de16446b6b379e8a7272b 557 TIGRFAM TIGR00649 MG423: beta-CASP ribonuclease, RNase J family 11 554 9.9E-183 T 28-03-2018 IPR004613 Ribonuclease J GO:0003723|GO:0046872 CO689_RS11810 c5d40f1d573de16446b6b379e8a7272b 557 Hamap MF_01491 Ribonuclease J [rnj]. 6 557 43.2 T 28-03-2018 IPR030854 Ribonuclease J, bacteria GO:0004521|GO:0004534|GO:0006396|GO:0008270|GO:0090501 CO689_RS08510 1e0acb4018a37c3ec43d71bdc2b48710 576 Gene3D G3DSA:1.20.1560.10 1 323 2.7E-69 T 28-03-2018 CO689_RS08510 1e0acb4018a37c3ec43d71bdc2b48710 576 SUPERFAMILY SSF90123 14 322 2.49E-71 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CO689_RS08510 1e0acb4018a37c3ec43d71bdc2b48710 576 SUPERFAMILY SSF52540 333 572 4.28E-86 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CO689_RS08510 1e0acb4018a37c3ec43d71bdc2b48710 576 Gene3D G3DSA:3.40.50.300 324 576 5.6E-74 T 28-03-2018 CO689_RS08510 1e0acb4018a37c3ec43d71bdc2b48710 576 Pfam PF00664 ABC transporter transmembrane region 31 293 3.2E-49 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CO689_RS08510 1e0acb4018a37c3ec43d71bdc2b48710 576 SMART SM00382 361 548 2.8E-16 T 28-03-2018 IPR003593 AAA+ ATPase domain CO689_RS08510 1e0acb4018a37c3ec43d71bdc2b48710 576 Pfam PF00005 ABC transporter 352 502 1.1E-31 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CO689_RS08510 1e0acb4018a37c3ec43d71bdc2b48710 576 ProSitePatterns PS00211 ABC transporters family signature. 474 488 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CO689_RS12310 a7b360689232c4c793ed3a404dd46853 364 Pfam PF01842 ACT domain 297 349 6.3E-8 T 28-03-2018 IPR002912 ACT domain CO689_RS12310 a7b360689232c4c793ed3a404dd46853 364 SUPERFAMILY SSF51735 5 171 1.58E-38 T 28-03-2018 IPR016040 NAD(P)-binding domain CO689_RS12310 a7b360689232c4c793ed3a404dd46853 364 Pfam PF02153 Prephenate dehydrogenase 18 275 2.1E-71 T 28-03-2018 IPR003099 Prephenate dehydrogenase GO:0004665|GO:0006571|GO:0008977|GO:0055114 KEGG: 00400+1.3.1.12|KEGG: 00401+1.3.1.12|MetaCyc: PWY-7303 CO689_RS12310 a7b360689232c4c793ed3a404dd46853 364 Gene3D G3DSA:3.40.50.720 2 173 3.4E-24 T 28-03-2018 CO689_RS12310 a7b360689232c4c793ed3a404dd46853 364 SUPERFAMILY SSF48179 175 284 1.59E-34 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CO689_RS12310 a7b360689232c4c793ed3a404dd46853 364 SUPERFAMILY SSF55021 295 359 3.82E-8 T 28-03-2018 CO689_RS12310 a7b360689232c4c793ed3a404dd46853 364 Gene3D G3DSA:1.10.3660.10 183 293 5.1E-27 T 28-03-2018 CO689_RS12310 a7b360689232c4c793ed3a404dd46853 364 Gene3D G3DSA:3.30.70.260 294 359 4.1E-8 T 28-03-2018 CO689_RS12270 de76d3bbcbfac9fc88b9af33ddd1ae6e 408 Pfam PF01594 AI-2E family transporter 38 373 3.0E-75 T 28-03-2018 IPR002549 Transmembrane protein TqsA-like CO689_RS01430 446ac0f707c90e380b64933bc500f331 156 Gene3D G3DSA:3.40.1280.10 1 156 4.8E-39 T 28-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal CO689_RS01430 446ac0f707c90e380b64933bc500f331 156 Hamap MF_01885 tRNA (cytidine(34)-2'-O)-methyltransferase [trmL]. 3 153 34.198 T 28-03-2018 IPR016914 tRNA (cytidine/uridine-2'-O-)-methyltransferase GO:0001510|GO:0008168 KEGG: 00260+2.1.1.20|MetaCyc: PWY-6004 CO689_RS01430 446ac0f707c90e380b64933bc500f331 156 TIGRFAM TIGR00185 tRNA_yibK_trmL: tRNA (cytidine(34)-2'-O)-methyltransferase 4 155 1.6E-62 T 28-03-2018 IPR016914 tRNA (cytidine/uridine-2'-O-)-methyltransferase GO:0001510|GO:0008168 KEGG: 00260+2.1.1.20|MetaCyc: PWY-6004 CO689_RS01430 446ac0f707c90e380b64933bc500f331 156 SUPERFAMILY SSF75217 4 154 8.5E-43 T 28-03-2018 IPR029028 Alpha/beta knot methyltransferases CO689_RS01430 446ac0f707c90e380b64933bc500f331 156 PIRSF PIRSF029256 2 156 1.9E-66 T 28-03-2018 IPR016914 tRNA (cytidine/uridine-2'-O-)-methyltransferase GO:0001510|GO:0008168 KEGG: 00260+2.1.1.20|MetaCyc: PWY-6004 CO689_RS01430 446ac0f707c90e380b64933bc500f331 156 Pfam PF00588 SpoU rRNA Methylase family 4 144 2.1E-33 T 28-03-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 CO689_RS10980 c87a2a67a2106b652c22a05b85f8ba68 153 Gene3D G3DSA:1.20.120.80 2 137 3.6E-11 T 28-03-2018 IPR013833 Cytochrome c oxidase, subunit III, 4-helical bundle GO:0004129|GO:0016020|GO:0022904 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CO689_RS10980 c87a2a67a2106b652c22a05b85f8ba68 153 Pfam PF04238 Protein of unknown function (DUF420) 6 134 1.2E-38 T 28-03-2018 IPR007352 Protein of unknown function DUF420 CO689_RS12790 2913bf4bf84f22f2e1ea4493cefd0e6e 241 Hamap MF_01813 Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE [ubiE]. 2 233 37.08 T 28-03-2018 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 CO689_RS12790 2913bf4bf84f22f2e1ea4493cefd0e6e 241 SUPERFAMILY SSF53335 5 232 1.36E-49 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CO689_RS12790 2913bf4bf84f22f2e1ea4493cefd0e6e 241 ProSitePatterns PS01184 ubiE/COQ5 methyltransferase family signature 2. 141 155 - T 28-03-2018 IPR023576 UbiE/COQ5 methyltransferase, conserved site GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895 CO689_RS12790 2913bf4bf84f22f2e1ea4493cefd0e6e 241 Pfam PF01209 ubiE/COQ5 methyltransferase family 5 233 3.0E-96 T 28-03-2018 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 CO689_RS12790 2913bf4bf84f22f2e1ea4493cefd0e6e 241 TIGRFAM TIGR01934 MenG_MenH_UbiE: ubiquinone/menaquinone biosynthesis methyltransferase 11 233 2.1E-86 T 28-03-2018 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 CO689_RS12790 2913bf4bf84f22f2e1ea4493cefd0e6e 241 Gene3D G3DSA:3.40.50.150 1 237 3.4E-46 T 28-03-2018 CO689_RS12790 2913bf4bf84f22f2e1ea4493cefd0e6e 241 ProSitePatterns PS01183 ubiE/COQ5 methyltransferase family signature 1. 22 37 - T 28-03-2018 IPR023576 UbiE/COQ5 methyltransferase, conserved site GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895 CO689_RS10940 9f2fb695003c62d5042f1f5343219508 615 SUPERFAMILY SSF54980 401 516 1.49E-26 T 28-03-2018 IPR035647 EF-G domain III/V-like CO689_RS10940 9f2fb695003c62d5042f1f5343219508 615 SUPERFAMILY SSF52540 4 210 1.06E-56 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CO689_RS10940 9f2fb695003c62d5042f1f5343219508 615 SUPERFAMILY SSF54980 305 390 1.73E-15 T 28-03-2018 IPR035647 EF-G domain III/V-like CO689_RS10940 9f2fb695003c62d5042f1f5343219508 615 PRINTS PR00315 GTP-binding elongation factor signature 54 62 1.3E-14 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CO689_RS10940 9f2fb695003c62d5042f1f5343219508 615 PRINTS PR00315 GTP-binding elongation factor signature 10 23 1.3E-14 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CO689_RS10940 9f2fb695003c62d5042f1f5343219508 615 PRINTS PR00315 GTP-binding elongation factor signature 126 135 1.3E-14 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CO689_RS10940 9f2fb695003c62d5042f1f5343219508 615 PRINTS PR00315 GTP-binding elongation factor signature 90 101 1.3E-14 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CO689_RS10940 9f2fb695003c62d5042f1f5343219508 615 PRINTS PR00315 GTP-binding elongation factor signature 74 84 1.3E-14 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CO689_RS10940 9f2fb695003c62d5042f1f5343219508 615 Pfam PF00679 Elongation factor G C-terminus 398 477 4.7E-22 T 28-03-2018 IPR000640 Elongation factor EFG, domain V-like CO689_RS10940 9f2fb695003c62d5042f1f5343219508 615 Pfam PF03144 Elongation factor Tu domain 2 222 292 1.3E-14 T 28-03-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 CO689_RS10940 9f2fb695003c62d5042f1f5343219508 615 TIGRFAM TIGR01394 TypA_BipA: GTP-binding protein TypA/BipA 8 602 7.3E-285 T 28-03-2018 IPR006298 GTP-binding protein TypA GO:0005525 CO689_RS10940 9f2fb695003c62d5042f1f5343219508 615 Gene3D G3DSA:2.40.30.10 205 305 4.1E-21 T 28-03-2018 CO689_RS10940 9f2fb695003c62d5042f1f5343219508 615 Gene3D G3DSA:2.40.50.250 496 576 9.6E-37 T 28-03-2018 CO689_RS10940 9f2fb695003c62d5042f1f5343219508 615 Pfam PF14492 Elongation Factor G, domain II 332 383 2.5E-6 T 28-03-2018 CO689_RS10940 9f2fb695003c62d5042f1f5343219508 615 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 9 144 3.0E-24 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 CO689_RS10940 9f2fb695003c62d5042f1f5343219508 615 Gene3D G3DSA:3.40.50.300 71 203 3.3E-31 T 28-03-2018 CO689_RS10940 9f2fb695003c62d5042f1f5343219508 615 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 47 62 - T 28-03-2018 IPR031157 Tr-type G domain, conserved site CO689_RS10940 9f2fb695003c62d5042f1f5343219508 615 Gene3D G3DSA:3.40.50.300 2 70 3.0E-10 T 28-03-2018 CO689_RS10940 9f2fb695003c62d5042f1f5343219508 615 Gene3D G3DSA:3.30.70.240 404 495 3.4E-18 T 28-03-2018 CO689_RS10940 9f2fb695003c62d5042f1f5343219508 615 Pfam PF00009 Elongation factor Tu GTP binding domain 7 197 2.4E-56 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CO689_RS10940 9f2fb695003c62d5042f1f5343219508 615 SUPERFAMILY SSF50447 155 302 1.12E-32 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain CO689_RS10940 9f2fb695003c62d5042f1f5343219508 615 Gene3D G3DSA:3.30.70.870 306 403 4.0E-32 T 28-03-2018 CO689_RS10940 9f2fb695003c62d5042f1f5343219508 615 SMART SM00838 398 483 1.5E-5 T 28-03-2018 IPR000640 Elongation factor EFG, domain V-like CO689_RS10535 f675114db1ff438478481fe95d607ca4 272 Gene3D G3DSA:3.90.226.10 1 211 1.0E-61 T 28-03-2018 CO689_RS10535 f675114db1ff438478481fe95d607ca4 272 TIGRFAM TIGR01929 menB: naphthoate synthase 11 268 1.2E-130 T 28-03-2018 IPR010198 1,4-Dihydroxy-2-naphthoyl-CoA synthase, MenB GO:0008935|GO:0009234 KEGG: 00130+4.1.3.36|MetaCyc: PWY-5837 CO689_RS10535 f675114db1ff438478481fe95d607ca4 272 Hamap MF_01934 1,4-dihydroxy-2-naphthoyl-CoA synthase [menB]. 5 271 55.314 T 28-03-2018 IPR010198 1,4-Dihydroxy-2-naphthoyl-CoA synthase, MenB GO:0008935|GO:0009234 KEGG: 00130+4.1.3.36|MetaCyc: PWY-5837 CO689_RS10535 f675114db1ff438478481fe95d607ca4 272 Gene3D G3DSA:1.10.12.10 212 260 2.1E-15 T 28-03-2018 IPR014748 Crontonase, C-terminal CO689_RS10535 f675114db1ff438478481fe95d607ca4 272 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 110 130 - T 28-03-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 CO689_RS10535 f675114db1ff438478481fe95d607ca4 272 Pfam PF00378 Enoyl-CoA hydratase/isomerase 20 267 5.6E-89 T 28-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CO689_RS10535 f675114db1ff438478481fe95d607ca4 272 SUPERFAMILY SSF52096 5 268 4.84E-79 T 28-03-2018 IPR029045 ClpP/crotonase-like domain CO689_RS09550 bc8127197ff4b48a971a2e591413a10c 234 Pfam PF00717 Peptidase S24-like 156 220 1.0E-15 T 28-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C CO689_RS09550 bc8127197ff4b48a971a2e591413a10c 234 Gene3D G3DSA:1.10.3100.10 4 134 7.7E-9 T 28-03-2018 IPR027910 YdiL-like domain CO689_RS09550 bc8127197ff4b48a971a2e591413a10c 234 Gene3D G3DSA:2.10.109.10 135 234 5.2E-23 T 28-03-2018 CO689_RS09550 bc8127197ff4b48a971a2e591413a10c 234 SUPERFAMILY SSF51306 122 233 3.01E-25 T 28-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C CO689_RS09550 bc8127197ff4b48a971a2e591413a10c 234 SUPERFAMILY SSF47413 5 66 1.54E-5 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CO689_RS13450 cb6d76d85e3f640eaca4ad99d2125f3a 370 Pfam PF03054 tRNA methyl transferase 7 356 2.0E-146 T 28-03-2018 CO689_RS13450 cb6d76d85e3f640eaca4ad99d2125f3a 370 Gene3D G3DSA:2.30.30.280 213 276 2.2E-25 T 28-03-2018 IPR023382 Adenine nucleotide alpha hydrolase-like domains GO:0016783 Reactome: R-HSA-6787450 CO689_RS13450 cb6d76d85e3f640eaca4ad99d2125f3a 370 Hamap MF_00144 tRNA-specific 2-thiouridylase MnmA [mnmA]. 6 357 40.147 T 28-03-2018 IPR004506 tRNA-specific 2-thiouridylase GO:0008033|GO:0016740 Reactome: R-HSA-6787450 CO689_RS13450 cb6d76d85e3f640eaca4ad99d2125f3a 370 TIGRFAM TIGR00420 trmU: tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase 7 356 6.6E-139 T 28-03-2018 IPR004506 tRNA-specific 2-thiouridylase GO:0008033|GO:0016740 Reactome: R-HSA-6787450 CO689_RS13450 cb6d76d85e3f640eaca4ad99d2125f3a 370 Gene3D G3DSA:2.40.30.10 278 369 1.8E-27 T 28-03-2018 CO689_RS13450 cb6d76d85e3f640eaca4ad99d2125f3a 370 SUPERFAMILY SSF52402 5 243 4.63E-60 T 28-03-2018 CO689_RS13450 cb6d76d85e3f640eaca4ad99d2125f3a 370 Gene3D G3DSA:3.40.50.620 1 212 4.9E-70 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CO689_RS01295 ccc6a177b96a00a491024204162967b0 524 Pfam PF00890 FAD binding domain 4 372 5.1E-61 T 28-03-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 CO689_RS01295 ccc6a177b96a00a491024204162967b0 524 SUPERFAMILY SSF56425 221 333 1.14E-29 T 28-03-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 CO689_RS01295 ccc6a177b96a00a491024204162967b0 524 SUPERFAMILY SSF46977 413 512 9.68E-14 T 28-03-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CO689_RS01295 ccc6a177b96a00a491024204162967b0 524 Gene3D G3DSA:1.20.58.100 405 505 6.4E-11 T 28-03-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CO689_RS01295 ccc6a177b96a00a491024204162967b0 524 Pfam PF02910 Fumarate reductase flavoprotein C-term 421 494 7.4E-7 T 28-03-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CO689_RS01295 ccc6a177b96a00a491024204162967b0 524 SUPERFAMILY SSF51905 3 247 2.69E-44 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CO689_RS01295 ccc6a177b96a00a491024204162967b0 524 SUPERFAMILY SSF51905 336 395 2.69E-44 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CO689_RS01295 ccc6a177b96a00a491024204162967b0 524 Gene3D G3DSA:3.50.50.60 2 395 1.1E-45 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CO689_RS01410 9de3138d10222e282e0f9d3624ff578b 275 SUPERFAMILY SSF55120 66 271 5.76E-54 T 28-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 CO689_RS01410 9de3138d10222e282e0f9d3624ff578b 275 Pfam PF00849 RNA pseudouridylate synthase 83 230 4.5E-25 T 28-03-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 CO689_RS01410 9de3138d10222e282e0f9d3624ff578b 275 TIGRFAM TIGR00005 rluA_subfam: pseudouridine synthase, RluA family 22 269 9.3E-60 T 28-03-2018 IPR006225 Pseudouridine synthase, RluC/RluD GO:0001522|GO:0003723|GO:0009451|GO:0009982 CO689_RS01410 9de3138d10222e282e0f9d3624ff578b 275 Gene3D G3DSA:3.30.2350.10 73 274 6.7E-52 T 28-03-2018 CO689_RS11650 25536595f0ce17b88d5dd5f246316a79 435 TIGRFAM TIGR00137 gid_trmFO: tRNA:m(5)U-54 methyltransferase 3 433 3.1E-222 T 28-03-2018 IPR004417 Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO GO:0005737|GO:0008033|GO:0047151|GO:0050660 CO689_RS11650 25536595f0ce17b88d5dd5f246316a79 435 Hamap MF_01037 Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO [trmFO]. 5 434 36.477 T 28-03-2018 IPR004417 Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO GO:0005737|GO:0008033|GO:0047151|GO:0050660 CO689_RS11650 25536595f0ce17b88d5dd5f246316a79 435 Pfam PF01134 Glucose inhibited division protein A 5 366 2.0E-114 T 28-03-2018 IPR002218 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG-related GO:0008033|GO:0050660 Reactome: R-HSA-6787450 CO689_RS11650 25536595f0ce17b88d5dd5f246316a79 435 ProSitePatterns PS01281 Glucose inhibited division protein A family signature 2. 336 359 - T 28-03-2018 IPR020595 MnmG-related, conserved site Reactome: R-HSA-6787450 CO689_RS11650 25536595f0ce17b88d5dd5f246316a79 435 SUPERFAMILY SSF51905 5 365 1.62E-31 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CO689_RS11650 25536595f0ce17b88d5dd5f246316a79 435 Gene3D G3DSA:3.50.50.60 2 377 1.0E-21 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CO689_RS06135 5a7937b483b15cc3a37479649d15a2e4 94 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 2 85 1.8E-12 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 CO689_RS06135 5a7937b483b15cc3a37479649d15a2e4 94 SUPERFAMILY SSF52794 1 89 4.97E-18 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 CO689_RS06135 5a7937b483b15cc3a37479649d15a2e4 94 Gene3D G3DSA:3.40.50.2300 1 93 7.5E-19 T 28-03-2018 CO689_RS10840 1c2979574261240aa6e8c080ecceb5ec 71 ProDom PD055417 UPF0356 TRANSCRIPTIONAL REGULATOR SP0122 SH1862 BLI01669/BL01628 MW0973 LMOF2365_1049 BCE33L3734 SPYM3_1619/SPS0248 3 60 4.0E-21 T 28-03-2018 IPR009907 Protein of unknown function DUF1447 CO689_RS10840 1c2979574261240aa6e8c080ecceb5ec 71 Hamap MF_01553 UPF0356 protein . 2 70 21.173 T 28-03-2018 IPR009907 Protein of unknown function DUF1447 CO689_RS10840 1c2979574261240aa6e8c080ecceb5ec 71 Pfam PF07288 Protein of unknown function (DUF1447) 3 68 7.2E-29 T 28-03-2018 IPR009907 Protein of unknown function DUF1447 CO689_RS02805 fb74ba1d45a83e6294356abeec8d0033 227 Pfam PF03006 Haemolysin-III related 25 220 8.3E-32 T 28-03-2018 IPR004254 AdipoR/Haemolysin-III-related GO:0016021 CO689_RS02805 fb74ba1d45a83e6294356abeec8d0033 227 TIGRFAM TIGR01065 hlyIII: channel protein, hemolysin III family 26 225 3.6E-53 T 28-03-2018 IPR005744 Hly-III GO:0016021|GO:0019835 CO689_RS09940 26ce0a1cffb4bc485ebc6a5c8d8e37ad 354 SUPERFAMILY SSF51905 142 299 2.06E-24 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CO689_RS09940 26ce0a1cffb4bc485ebc6a5c8d8e37ad 354 SUPERFAMILY SSF51905 2 189 4.53E-17 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CO689_RS09940 26ce0a1cffb4bc485ebc6a5c8d8e37ad 354 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 142 167 2.1E-6 T 28-03-2018 CO689_RS09940 26ce0a1cffb4bc485ebc6a5c8d8e37ad 354 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 265 272 2.1E-6 T 28-03-2018 CO689_RS09940 26ce0a1cffb4bc485ebc6a5c8d8e37ad 354 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 3 25 2.1E-6 T 28-03-2018 CO689_RS09940 26ce0a1cffb4bc485ebc6a5c8d8e37ad 354 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 3 281 8.4E-37 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CO689_RS09940 26ce0a1cffb4bc485ebc6a5c8d8e37ad 354 Gene3D G3DSA:3.50.50.60 93 221 2.9E-23 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CO689_RS09940 26ce0a1cffb4bc485ebc6a5c8d8e37ad 354 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 142 160 7.0E-6 T 28-03-2018 CO689_RS09940 26ce0a1cffb4bc485ebc6a5c8d8e37ad 354 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 250 272 7.0E-6 T 28-03-2018 CO689_RS09940 26ce0a1cffb4bc485ebc6a5c8d8e37ad 354 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 95 113 7.0E-6 T 28-03-2018 CO689_RS09940 26ce0a1cffb4bc485ebc6a5c8d8e37ad 354 Gene3D G3DSA:3.50.50.60 7 92 0.014 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CO689_RS09940 26ce0a1cffb4bc485ebc6a5c8d8e37ad 354 Gene3D G3DSA:3.50.50.60 222 315 3.0E-5 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CO689_RS12600 156208ba3dbd0d88e75c6fab2e60c07d 144 SUPERFAMILY SSF51316 5 137 1.62E-53 T 28-03-2018 IPR011057 Mss4-like CO689_RS12600 156208ba3dbd0d88e75c6fab2e60c07d 144 Pfam PF01641 SelR domain 6 122 4.7E-45 T 28-03-2018 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 CO689_RS12600 156208ba3dbd0d88e75c6fab2e60c07d 144 TIGRFAM TIGR00357 TIGR00357: methionine-R-sulfoxide reductase 5 131 1.2E-55 T 28-03-2018 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 CO689_RS12600 156208ba3dbd0d88e75c6fab2e60c07d 144 Gene3D G3DSA:2.170.150.20 2 139 3.4E-47 T 28-03-2018 CO689_RS13730 d34c923ffa6b9a0ff4000e9cba581b0a 420 TIGRFAM TIGR00382 clpX: ATP-dependent Clp protease, ATP-binding subunit ClpX 3 405 9.0E-200 T 28-03-2018 IPR004487 Clp protease, ATP-binding subunit ClpX GO:0005524|GO:0006457|GO:0051082 CO689_RS13730 d34c923ffa6b9a0ff4000e9cba581b0a 420 Gene3D G3DSA:1.10.8.60 311 402 2.1E-31 T 28-03-2018 CO689_RS13730 d34c923ffa6b9a0ff4000e9cba581b0a 420 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 311 389 2.0E-16 T 28-03-2018 IPR019489 Clp ATPase, C-terminal CO689_RS13730 d34c923ffa6b9a0ff4000e9cba581b0a 420 SMART SM00994 10 49 1.2E-21 T 28-03-2018 IPR010603 Zinc finger, ClpX C4-type GO:0008270|GO:0046983 CO689_RS13730 d34c923ffa6b9a0ff4000e9cba581b0a 420 SUPERFAMILY SSF57716 11 46 4.42E-11 T 28-03-2018 CO689_RS13730 d34c923ffa6b9a0ff4000e9cba581b0a 420 SMART SM01086 311 403 4.3E-31 T 28-03-2018 IPR019489 Clp ATPase, C-terminal CO689_RS13730 d34c923ffa6b9a0ff4000e9cba581b0a 420 Pfam PF06689 ClpX C4-type zinc finger 12 48 1.0E-18 T 28-03-2018 IPR010603 Zinc finger, ClpX C4-type GO:0008270|GO:0046983 CO689_RS13730 d34c923ffa6b9a0ff4000e9cba581b0a 420 SMART SM00382 109 262 1.4E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain CO689_RS13730 d34c923ffa6b9a0ff4000e9cba581b0a 420 Pfam PF07724 AAA domain (Cdc48 subfamily) 109 305 4.7E-48 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CO689_RS13730 d34c923ffa6b9a0ff4000e9cba581b0a 420 SUPERFAMILY SSF52540 59 395 6.63E-75 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CO689_RS13730 d34c923ffa6b9a0ff4000e9cba581b0a 420 Hamap MF_00175 ATP-dependent Clp protease ATP-binding subunit ClpX [clpX]. 4 409 51.419 T 28-03-2018 IPR004487 Clp protease, ATP-binding subunit ClpX GO:0005524|GO:0006457|GO:0051082 CO689_RS13730 d34c923ffa6b9a0ff4000e9cba581b0a 420 Gene3D G3DSA:3.40.50.300 53 309 9.5E-71 T 28-03-2018 CO689_RS04185 5ba5ade2dbb497eae748ffec6b9c313b 222 Pfam PF00005 ABC transporter 20 162 6.3E-33 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CO689_RS04185 5ba5ade2dbb497eae748ffec6b9c313b 222 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CO689_RS04185 5ba5ade2dbb497eae748ffec6b9c313b 222 Gene3D G3DSA:3.40.50.300 1 218 1.1E-58 T 28-03-2018 CO689_RS04185 5ba5ade2dbb497eae748ffec6b9c313b 222 SMART SM00382 28 211 4.7E-15 T 28-03-2018 IPR003593 AAA+ ATPase domain CO689_RS04185 5ba5ade2dbb497eae748ffec6b9c313b 222 SUPERFAMILY SSF52540 3 212 1.01E-55 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CO689_RS01380 7ad08a6ac1d6da53809ca2c7317eba83 117 Hamap MF_01526 UPF0342 protein . 2 113 18.384 T 28-03-2018 IPR010368 Control of competence regulator ComK, YlbF/YmcA CO689_RS01380 7ad08a6ac1d6da53809ca2c7317eba83 117 Pfam PF06133 Control of competence regulator ComK, YlbF/YmcA 6 108 9.5E-24 T 28-03-2018 IPR010368 Control of competence regulator ComK, YlbF/YmcA CO689_RS01380 7ad08a6ac1d6da53809ca2c7317eba83 117 SUPERFAMILY SSF158622 3 112 5.49E-33 T 28-03-2018 IPR023378 YheA/YmcA-like domain CO689_RS01380 7ad08a6ac1d6da53809ca2c7317eba83 117 Gene3D G3DSA:1.20.1500.10 4 109 9.3E-26 T 28-03-2018 IPR023378 YheA/YmcA-like domain CO689_RS01435 3a2dc0bc19fa5b50a613fab655c8386b 374 Gene3D G3DSA:3.30.70.20 41 192 3.0E-4 T 28-03-2018 CO689_RS01435 3a2dc0bc19fa5b50a613fab655c8386b 374 Hamap MF_00916 Epoxyqueuosine reductase [queG]. 3 308 42.618 T 28-03-2018 IPR004453 Epoxyqueuosine reductase QueG GO:0008033|GO:0008616|GO:0016491 MetaCyc: PWY-6700 CO689_RS01435 3a2dc0bc19fa5b50a613fab655c8386b 374 Pfam PF13484 4Fe-4S double cluster binding domain 188 250 1.1E-14 T 28-03-2018 CO689_RS01435 3a2dc0bc19fa5b50a613fab655c8386b 374 SUPERFAMILY SSF54862 164 255 2.68E-14 T 28-03-2018 CO689_RS01435 3a2dc0bc19fa5b50a613fab655c8386b 374 Gene3D G3DSA:1.25.40.70 257 371 3.0E-7 T 28-03-2018 CO689_RS01435 3a2dc0bc19fa5b50a613fab655c8386b 374 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 188 199 - T 28-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CO689_RS01435 3a2dc0bc19fa5b50a613fab655c8386b 374 TIGRFAM TIGR00276 TIGR00276: epoxyqueuosine reductase 10 341 6.8E-122 T 28-03-2018 IPR004453 Epoxyqueuosine reductase QueG GO:0008033|GO:0008616|GO:0016491 MetaCyc: PWY-6700 CO689_RS01435 3a2dc0bc19fa5b50a613fab655c8386b 374 Gene3D G3DSA:3.30.70.20 193 251 2.8E-8 T 28-03-2018 CO689_RS01435 3a2dc0bc19fa5b50a613fab655c8386b 374 Pfam PF08331 Domain of unknown function (DUF1730) 57 135 7.4E-17 T 28-03-2018 IPR013542 Domain of unknown function DUF1730 MetaCyc: PWY-6700 CO689_RS01435 3a2dc0bc19fa5b50a613fab655c8386b 374 Pfam PF13646 HEAT repeats 299 366 7.5E-9 T 28-03-2018 CO689_RS01435 3a2dc0bc19fa5b50a613fab655c8386b 374 SUPERFAMILY SSF48371 284 371 1.99E-10 T 28-03-2018 IPR016024 Armadillo-type fold GO:0005488 CO689_RS06690 75704b62c2a938ebdf9636d4d0afb36d 560 Gene3D G3DSA:2.40.10.10 356 452 3.5E-6 T 28-03-2018 CO689_RS06690 75704b62c2a938ebdf9636d4d0afb36d 560 SUPERFAMILY SSF50494 335 542 1.55E-23 T 28-03-2018 IPR009003 Peptidase S1, PA clan CO689_RS06690 75704b62c2a938ebdf9636d4d0afb36d 560 Pfam PF00089 Trypsin 365 539 5.8E-10 T 28-03-2018 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 CO689_RS06690 75704b62c2a938ebdf9636d4d0afb36d 560 Gene3D G3DSA:2.40.10.10 469 558 4.9E-9 T 28-03-2018 CO689_RS04640 f08daf380f612c46d39ba810fa0649c6 252 Gene3D G3DSA:3.20.20.370 2 249 6.0E-108 T 28-03-2018 CO689_RS04640 f08daf380f612c46d39ba810fa0649c6 252 Hamap MF_00691 UPF0271 protein YbgL [ybgL]. 1 245 46.083 T 28-03-2018 IPR005501 Uncharacterised protein family UPF0271, LamB/YcsF CO689_RS04640 f08daf380f612c46d39ba810fa0649c6 252 SUPERFAMILY SSF88713 1 250 6.08E-103 T 28-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 CO689_RS04640 f08daf380f612c46d39ba810fa0649c6 252 Pfam PF03746 LamB/YcsF family 3 240 9.0E-105 T 28-03-2018 IPR005501 Uncharacterised protein family UPF0271, LamB/YcsF CO689_RS11825 43e7eff092cb51803551d9b0cfce2682 422 Gene3D G3DSA:3.30.830.10 13 224 5.3E-25 T 28-03-2018 CO689_RS11825 43e7eff092cb51803551d9b0cfce2682 422 SUPERFAMILY SSF63411 243 411 2.17E-28 T 28-03-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 CO689_RS11825 43e7eff092cb51803551d9b0cfce2682 422 SUPERFAMILY SSF63411 15 225 2.14E-24 T 28-03-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 CO689_RS11825 43e7eff092cb51803551d9b0cfce2682 422 Pfam PF05193 Peptidase M16 inactive domain 181 356 4.9E-28 T 28-03-2018 IPR007863 Peptidase M16, C-terminal CO689_RS11825 43e7eff092cb51803551d9b0cfce2682 422 Gene3D G3DSA:3.30.830.10 230 418 9.8E-26 T 28-03-2018 CO689_RS10155 bdeb5a70fbd6324657673c565515f48c 414 PIRSF PIRSF000447 2 414 9.6E-183 T 28-03-2018 IPR017568 3-oxoacyl-[acyl-carrier-protein] synthase 2 GO:0006633|GO:0016747 CO689_RS10155 bdeb5a70fbd6324657673c565515f48c 414 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 156 172 - T 28-03-2018 IPR018201 Beta-ketoacyl synthase, active site CO689_RS10155 bdeb5a70fbd6324657673c565515f48c 414 SUPERFAMILY SSF53901 5 252 2.04E-78 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CO689_RS10155 bdeb5a70fbd6324657673c565515f48c 414 SMART SM00825 Beta-ketoacyl synthase 7 414 5.0E-17 T 28-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CO689_RS10155 bdeb5a70fbd6324657673c565515f48c 414 SUPERFAMILY SSF53901 215 412 1.31E-72 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CO689_RS10155 bdeb5a70fbd6324657673c565515f48c 414 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 255 368 3.5E-37 T 28-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal CO689_RS10155 bdeb5a70fbd6324657673c565515f48c 414 Gene3D G3DSA:3.40.47.10 7 260 1.7E-80 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CO689_RS10155 bdeb5a70fbd6324657673c565515f48c 414 TIGRFAM TIGR03150 fabF: beta-ketoacyl-acyl-carrier-protein synthase II 5 410 3.2E-193 T 28-03-2018 IPR017568 3-oxoacyl-[acyl-carrier-protein] synthase 2 GO:0006633|GO:0016747 CO689_RS10155 bdeb5a70fbd6324657673c565515f48c 414 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 5 247 7.2E-62 T 28-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal CO689_RS10155 bdeb5a70fbd6324657673c565515f48c 414 Gene3D G3DSA:3.40.47.10 263 414 1.8E-52 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CO689_RS06880 51c0dfa88c5c4a087e5638c76d7df60f 169 PIRSF PIRSF032209 1 167 2.6E-70 T 28-03-2018 IPR016992 Uncharacterised conserved protein UCP032209 CO689_RS06880 51c0dfa88c5c4a087e5638c76d7df60f 169 Pfam PF07799 Protein of unknown function (DUF1643) 21 155 2.8E-23 T 28-03-2018 IPR012441 Protein of unknown function DUF1643 CO689_RS11885 54361032eda7554446b66596353f9400 265 SUPERFAMILY SSF56300 1 256 1.31E-79 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CO689_RS11885 54361032eda7554446b66596353f9400 265 TIGRFAM TIGR00282 TIGR00282: metallophosphoesterase, MG_246/BB_0505 family 1 262 3.2E-104 T 28-03-2018 IPR005235 Metallophosphoesterase, YmdB-like CO689_RS11885 54361032eda7554446b66596353f9400 265 Pfam PF13277 YmdB-like protein 4 254 8.9E-106 T 28-03-2018 IPR005235 Metallophosphoesterase, YmdB-like CO689_RS11885 54361032eda7554446b66596353f9400 265 Gene3D G3DSA:3.60.21.10 1 264 7.0E-47 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CO689_RS11885 54361032eda7554446b66596353f9400 265 PIRSF PIRSF004789 1 262 3.6E-101 T 28-03-2018 IPR005235 Metallophosphoesterase, YmdB-like CO689_RS11330 b7193214bcf392e2ce598b251ab285eb 433 TIGRFAM TIGR00801 ncs2: uracil-xanthine permease 22 422 2.2E-128 T 28-03-2018 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 CO689_RS11330 b7193214bcf392e2ce598b251ab285eb 433 ProSitePatterns PS01116 Xanthine/uracil permeases family signature. 346 366 - T 28-03-2018 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 CO689_RS11330 b7193214bcf392e2ce598b251ab285eb 433 Pfam PF00860 Permease family 24 396 1.7E-107 T 28-03-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 CO689_RS06050 5ca23a4eca4b15a27e58f105d1267ff5 429 Gene3D G3DSA:1.20.1250.20 207 423 1.0E-19 T 28-03-2018 CO689_RS06050 5ca23a4eca4b15a27e58f105d1267ff5 429 Gene3D G3DSA:1.20.1250.20 14 204 2.3E-20 T 28-03-2018 CO689_RS06050 5ca23a4eca4b15a27e58f105d1267ff5 429 SUPERFAMILY SSF103473 8 411 1.29E-47 T 28-03-2018 IPR020846 Major facilitator superfamily domain CO689_RS06050 5ca23a4eca4b15a27e58f105d1267ff5 429 Pfam PF07690 Major Facilitator Superfamily 22 370 4.1E-29 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CO689_RS02895 87d719c0f19be1ffad44590e6593b2a0 518 Pfam PF02028 BCCT, betaine/carnitine/choline family transporter 9 491 2.9E-185 T 28-03-2018 IPR000060 BCCT transporter family GO:0005215|GO:0006810|GO:0016020 CO689_RS02895 87d719c0f19be1ffad44590e6593b2a0 518 TIGRFAM TIGR00842 bcct: transporter, betaine/carnitine/choline transporter (BCCT) family 48 491 1.6E-154 T 28-03-2018 IPR000060 BCCT transporter family GO:0005215|GO:0006810|GO:0016020 CO689_RS02895 87d719c0f19be1ffad44590e6593b2a0 518 ProSitePatterns PS01303 BCCT family of transporters signature. 313 322 - T 28-03-2018 IPR018093 BCCT transporter, conserved site GO:0005215|GO:0006810|GO:0016020 CO689_RS08185 7290476517e6895c3867320d6fb85afa 242 TIGRFAM TIGR00502 nagB: glucosamine-6-phosphate deaminase 2 240 8.4E-77 T 28-03-2018 IPR004547 Glucosamine-6-phosphate isomerase GO:0004342|GO:0006044 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906|Reactome: R-HSA-70326 CO689_RS08185 7290476517e6895c3867320d6fb85afa 242 Hamap MF_01241 Glucosamine-6-phosphate deaminase [nagB]. 1 242 40.838 T 28-03-2018 IPR004547 Glucosamine-6-phosphate isomerase GO:0004342|GO:0006044 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906|Reactome: R-HSA-70326 CO689_RS08185 7290476517e6895c3867320d6fb85afa 242 SUPERFAMILY SSF100950 2 239 1.36E-81 T 28-03-2018 CO689_RS08185 7290476517e6895c3867320d6fb85afa 242 Gene3D G3DSA:3.40.50.1360 1 242 2.6E-67 T 28-03-2018 CO689_RS08185 7290476517e6895c3867320d6fb85afa 242 Pfam PF01182 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase 22 225 5.5E-20 T 28-03-2018 IPR006148 Glucosamine/galactosamine-6-phosphate isomerase GO:0005975 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906 CO689_RS13205 03f3fd6a2e50295f7dd77867a8038db1 369 Pfam PF04545 Sigma-70, region 4 304 357 5.1E-20 T 28-03-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CO689_RS13205 03f3fd6a2e50295f7dd77867a8038db1 369 TIGRFAM TIGR02393 RpoD_Cterm: RNA polymerase sigma factor RpoD 132 368 3.8E-124 T 28-03-2018 IPR012760 RNA polymerase sigma factor RpoD, C-terminal GO:0003677|GO:0006352|GO:0006355|GO:0016987 CO689_RS13205 03f3fd6a2e50295f7dd77867a8038db1 369 Gene3D G3DSA:1.10.10.10 298 369 4.4E-31 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS13205 03f3fd6a2e50295f7dd77867a8038db1 369 Pfam PF04539 Sigma-70 region 3 215 291 3.7E-31 T 28-03-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CO689_RS13205 03f3fd6a2e50295f7dd77867a8038db1 369 Gene3D G3DSA:1.10.601.10 2 205 5.6E-76 T 28-03-2018 CO689_RS13205 03f3fd6a2e50295f7dd77867a8038db1 369 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 160 173 - T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CO689_RS13205 03f3fd6a2e50295f7dd77867a8038db1 369 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 329 355 - T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CO689_RS13205 03f3fd6a2e50295f7dd77867a8038db1 369 Gene3D G3DSA:1.10.10.10 206 256 8.9E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS13205 03f3fd6a2e50295f7dd77867a8038db1 369 Hamap MF_00963 RNA polymerase sigma factor RpoD [rpoD]. 14 369 33.859 T 28-03-2018 IPR028630 RNA polymerase sigma factor RpoD GO:0006352|GO:0016987 CO689_RS13205 03f3fd6a2e50295f7dd77867a8038db1 369 Pfam PF00140 Sigma-70 factor, region 1.2 98 130 5.0E-18 T 28-03-2018 IPR009042 RNA polymerase sigma-70 region 1.2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CO689_RS13205 03f3fd6a2e50295f7dd77867a8038db1 369 PRINTS PR00046 Major sigma-70 factor signature 308 320 3.0E-32 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CO689_RS13205 03f3fd6a2e50295f7dd77867a8038db1 369 PRINTS PR00046 Major sigma-70 factor signature 329 344 3.0E-32 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CO689_RS13205 03f3fd6a2e50295f7dd77867a8038db1 369 PRINTS PR00046 Major sigma-70 factor signature 160 173 3.0E-32 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CO689_RS13205 03f3fd6a2e50295f7dd77867a8038db1 369 PRINTS PR00046 Major sigma-70 factor signature 184 192 3.0E-32 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CO689_RS13205 03f3fd6a2e50295f7dd77867a8038db1 369 PRINTS PR00046 Major sigma-70 factor signature 344 355 3.0E-32 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CO689_RS13205 03f3fd6a2e50295f7dd77867a8038db1 369 Pfam PF03979 Sigma-70 factor, region 1.1 25 82 1.8E-14 T 28-03-2018 IPR007127 RNA polymerase sigma factor 70, region 1.1 GO:0003677|GO:0006355 CO689_RS13205 03f3fd6a2e50295f7dd77867a8038db1 369 SUPERFAMILY SSF88946 97 206 2.49E-53 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CO689_RS13205 03f3fd6a2e50295f7dd77867a8038db1 369 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 134 357 6.0E-39 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CO689_RS13205 03f3fd6a2e50295f7dd77867a8038db1 369 SUPERFAMILY SSF88659 266 367 6.17E-30 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CO689_RS13205 03f3fd6a2e50295f7dd77867a8038db1 369 Pfam PF04542 Sigma-70 region 2 136 205 4.2E-22 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CO689_RS13205 03f3fd6a2e50295f7dd77867a8038db1 369 SUPERFAMILY SSF88659 209 282 4.51E-22 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CO689_RS00705 e04c9348f6c01d27ec59bc8db4621b68 686 Gene3D G3DSA:3.40.1190.10 97 323 1.9E-41 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CO689_RS00705 e04c9348f6c01d27ec59bc8db4621b68 686 Gene3D G3DSA:3.90.190.20 337 479 2.1E-14 T 28-03-2018 CO689_RS00705 e04c9348f6c01d27ec59bc8db4621b68 686 Pfam PF08245 Mur ligase middle domain 121 311 1.6E-34 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CO689_RS00705 e04c9348f6c01d27ec59bc8db4621b68 686 SUPERFAMILY SSF53623 106 320 7.2E-36 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CO689_RS00705 e04c9348f6c01d27ec59bc8db4621b68 686 SUPERFAMILY SSF53244 340 458 8.51E-17 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CO689_RS04940 7fb422be9d5c128a46fe1a2f9c467354 523 Gene3D G3DSA:1.20.5.420 279 340 1.0E-12 T 28-03-2018 CO689_RS04940 7fb422be9d5c128a46fe1a2f9c467354 523 Gene3D G3DSA:1.20.5.420 98 154 2.4E-10 T 28-03-2018 CO689_RS04940 7fb422be9d5c128a46fe1a2f9c467354 523 Gene3D G3DSA:1.20.5.420 214 272 2.3E-11 T 28-03-2018 CO689_RS04940 7fb422be9d5c128a46fe1a2f9c467354 523 Pfam PF04650 YSIRK type signal peptide 2 27 5.9E-8 T 28-03-2018 IPR005877 YSIRK Gram-positive signal peptide GO:0016020 CO689_RS04940 7fb422be9d5c128a46fe1a2f9c467354 523 Pfam PF00746 LPXTG cell wall anchor motif 480 523 1.3E-6 T 28-03-2018 IPR019948 Gram-positive LPXTG cell wall anchor CO689_RS04940 7fb422be9d5c128a46fe1a2f9c467354 523 Gene3D G3DSA:1.20.5.420 155 212 6.7E-9 T 28-03-2018 CO689_RS04940 7fb422be9d5c128a46fe1a2f9c467354 523 SUPERFAMILY SSF46997 211 244 2.93E-5 T 28-03-2018 IPR009063 Immunoglobulin/albumin-binding domain GO:0009405 CO689_RS04940 7fb422be9d5c128a46fe1a2f9c467354 523 TIGRFAM TIGR01168 YSIRK_signal: gram-positive signal peptide, YSIRK family 3 36 2.5E-11 T 28-03-2018 IPR005877 YSIRK Gram-positive signal peptide GO:0016020 CO689_RS04940 7fb422be9d5c128a46fe1a2f9c467354 523 SUPERFAMILY SSF46997 278 331 1.36E-5 T 28-03-2018 IPR009063 Immunoglobulin/albumin-binding domain GO:0009405 CO689_RS04940 7fb422be9d5c128a46fe1a2f9c467354 523 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 486 520 0.001 T 28-03-2018 CO689_RS04940 7fb422be9d5c128a46fe1a2f9c467354 523 Pfam PF01468 GA module 207 243 3.6E-6 T 28-03-2018 IPR002988 Protein G-related albumin-binding (GA) module GO:0009405 CO689_RS04940 7fb422be9d5c128a46fe1a2f9c467354 523 Pfam PF01468 GA module 277 308 5.3E-6 T 28-03-2018 IPR002988 Protein G-related albumin-binding (GA) module GO:0009405 CO689_RS04940 7fb422be9d5c128a46fe1a2f9c467354 523 Gene3D G3DSA:1.20.5.420 37 95 1.1E-9 T 28-03-2018 CO689_RS04940 7fb422be9d5c128a46fe1a2f9c467354 523 Gene3D G3DSA:1.20.5.420 415 474 4.4E-8 T 28-03-2018 CO689_RS06195 aab13edaad1050e1fcc8c86b10c48706 439 SUPERFAMILY SSF56672 37 159 7.38E-15 T 28-03-2018 CO689_RS06195 aab13edaad1050e1fcc8c86b10c48706 439 SUPERFAMILY SSF56672 209 331 7.38E-15 T 28-03-2018 CO689_RS06195 aab13edaad1050e1fcc8c86b10c48706 439 Pfam PF00078 Reverse transcriptase (RNA-dependent DNA polymerase) 215 328 3.8E-13 T 28-03-2018 IPR000477 Reverse transcriptase domain CO689_RS06195 aab13edaad1050e1fcc8c86b10c48706 439 Gene3D G3DSA:3.30.70.270 106 329 5.3E-20 T 28-03-2018 CO689_RS07140 131f9dcc068c4f992814fbd037b77802 327 SMART SM00894 289 325 4.5E-14 T 28-03-2018 IPR008613 Excalibur calcium-binding domain CO689_RS07140 131f9dcc068c4f992814fbd037b77802 327 SUPERFAMILY SSF50199 129 258 3.92E-35 T 28-03-2018 IPR016071 Staphylococcal nuclease (SNase-like), OB-fold CO689_RS07140 131f9dcc068c4f992814fbd037b77802 327 ProSitePatterns PS01123 Thermonuclease family signature 1. 132 156 - T 28-03-2018 IPR002071 Thermonuclease active site GO:0003676|GO:0004518 Reactome: R-HSA-6802952 CO689_RS07140 131f9dcc068c4f992814fbd037b77802 327 Pfam PF00565 Staphylococcal nuclease homologue 147 254 2.2E-34 T 28-03-2018 IPR016071 Staphylococcal nuclease (SNase-like), OB-fold CO689_RS07140 131f9dcc068c4f992814fbd037b77802 327 Gene3D G3DSA:2.40.50.90 121 262 5.3E-37 T 28-03-2018 IPR035437 Staphylococcal nuclease (SNase-like), OB-fold/extended TUDOR domain CO689_RS07140 131f9dcc068c4f992814fbd037b77802 327 SMART SM00318 121 255 2.0E-40 T 28-03-2018 IPR016071 Staphylococcal nuclease (SNase-like), OB-fold CO689_RS07140 131f9dcc068c4f992814fbd037b77802 327 Pfam PF05901 Excalibur calcium-binding domain 290 325 2.0E-14 T 28-03-2018 IPR008613 Excalibur calcium-binding domain CO689_RS07140 131f9dcc068c4f992814fbd037b77802 327 ProSitePatterns PS01284 Thermonuclease family signature 2. 196 206 - T 28-03-2018 IPR002071 Thermonuclease active site GO:0003676|GO:0004518 Reactome: R-HSA-6802952 CO689_RS02555 27e562113209951ab4b190674b356416 285 Pfam PF01116 Fructose-bisphosphate aldolase class-II 4 284 1.3E-102 T 28-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 CO689_RS02555 27e562113209951ab4b190674b356416 285 Gene3D G3DSA:3.20.20.70 1 285 2.4E-104 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CO689_RS02555 27e562113209951ab4b190674b356416 285 SUPERFAMILY SSF51569 1 285 6.59E-105 T 28-03-2018 CO689_RS02555 27e562113209951ab4b190674b356416 285 TIGRFAM TIGR01859 fruc_bis_ald_: fructose-1,6-bisphosphate aldolase, class II 3 285 5.9E-129 T 28-03-2018 IPR011289 Fructose-1,6-bisphosphate aldolase, class 2 GO:0004332|GO:0006096|GO:0008270|GO:0030388 KEGG: 00010+4.1.2.13|KEGG: 00030+4.1.2.13|KEGG: 00051+4.1.2.13|KEGG: 00680+4.1.2.13|KEGG: 00710+4.1.2.13|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 CO689_RS02555 27e562113209951ab4b190674b356416 285 TIGRFAM TIGR00167 cbbA: ketose-bisphosphate aldolase 1 285 2.6E-115 T 28-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 CO689_RS02555 27e562113209951ab4b190674b356416 285 PIRSF PIRSF001359 1 285 2.8E-127 T 28-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 CO689_RS02555 27e562113209951ab4b190674b356416 285 ProSitePatterns PS00806 Fructose-bisphosphate aldolase class-II signature 2. 134 145 - T 28-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 CO689_RS11985 ca714c59a14b23a4bb4834d5a7c9484d 555 ProSitePatterns PS00977 FAD-dependent glycerol-3-phosphate dehydrogenase signature 1. 25 42 - T 28-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 CO689_RS11985 ca714c59a14b23a4bb4834d5a7c9484d 555 Pfam PF16901 C-terminal domain of alpha-glycerophosphate oxidase 405 531 1.8E-25 T 28-03-2018 IPR031656 Alpha-glycerophosphate oxidase, C-terminal KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 CO689_RS11985 ca714c59a14b23a4bb4834d5a7c9484d 555 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 20 32 6.6E-31 T 28-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 CO689_RS11985 ca714c59a14b23a4bb4834d5a7c9484d 555 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 338 344 6.6E-31 T 28-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 CO689_RS11985 ca714c59a14b23a4bb4834d5a7c9484d 555 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 368 380 6.6E-31 T 28-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 CO689_RS11985 ca714c59a14b23a4bb4834d5a7c9484d 555 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 94 106 6.6E-31 T 28-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 CO689_RS11985 ca714c59a14b23a4bb4834d5a7c9484d 555 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 33 43 6.6E-31 T 28-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 CO689_RS11985 ca714c59a14b23a4bb4834d5a7c9484d 555 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 49 61 6.6E-31 T 28-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 CO689_RS11985 ca714c59a14b23a4bb4834d5a7c9484d 555 ProSitePatterns PS00978 FAD-dependent glycerol-3-phosphate dehydrogenase signature 2. 373 383 - T 28-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 CO689_RS11985 ca714c59a14b23a4bb4834d5a7c9484d 555 SUPERFAMILY SSF51905 157 238 1.57E-35 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CO689_RS11985 ca714c59a14b23a4bb4834d5a7c9484d 555 SUPERFAMILY SSF51905 15 113 1.57E-35 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CO689_RS11985 ca714c59a14b23a4bb4834d5a7c9484d 555 Pfam PF01266 FAD dependent oxidoreductase 21 352 1.6E-57 T 28-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 CO689_RS11985 ca714c59a14b23a4bb4834d5a7c9484d 555 Gene3D G3DSA:3.30.9.10 206 345 1.0E-41 T 28-03-2018 CO689_RS11985 ca714c59a14b23a4bb4834d5a7c9484d 555 Gene3D G3DSA:3.30.9.10 98 205 6.0E-10 T 28-03-2018 CO689_RS11985 ca714c59a14b23a4bb4834d5a7c9484d 555 SUPERFAMILY SSF54373 249 344 6.15E-13 T 28-03-2018 CO689_RS11985 ca714c59a14b23a4bb4834d5a7c9484d 555 Gene3D G3DSA:3.50.50.60 4 94 1.2E-7 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CO689_RS03735 e9609bc5365cbc778a815e0064bbabe9 315 Gene3D G3DSA:1.20.58.340 248 315 2.2E-24 T 28-03-2018 CO689_RS03735 e9609bc5365cbc778a815e0064bbabe9 315 SUPERFAMILY SSF143865 7 246 3.79E-46 T 28-03-2018 CO689_RS03735 e9609bc5365cbc778a815e0064bbabe9 315 Gene3D G3DSA:1.20.58.340 123 247 2.1E-15 T 28-03-2018 CO689_RS03735 e9609bc5365cbc778a815e0064bbabe9 315 SUPERFAMILY SSF144083 250 313 3.79E-23 T 28-03-2018 CO689_RS03735 e9609bc5365cbc778a815e0064bbabe9 315 TIGRFAM TIGR00383 corA: magnesium and cobalt transport protein CorA 19 313 4.9E-70 T 28-03-2018 IPR004488 Magnesium/cobalt transport protein CorA GO:0006824|GO:0015087|GO:0015095|GO:0015693|GO:0016020 CO689_RS03735 e9609bc5365cbc778a815e0064bbabe9 315 Pfam PF01544 CorA-like Mg2+ transporter protein 27 311 4.0E-72 T 28-03-2018 IPR002523 Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB GO:0016020|GO:0030001|GO:0046873|GO:0055085 CO689_RS03735 e9609bc5365cbc778a815e0064bbabe9 315 Gene3D G3DSA:3.30.460.20 1 122 9.4E-21 T 28-03-2018 CO689_RS02460 23106015b167dbc0d65af2125efbf07e 179 TIGRFAM TIGR01145 ATP_synt_delta: ATP synthase F1, delta subunit 4 174 1.2E-30 T 28-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CO689_RS02460 23106015b167dbc0d65af2125efbf07e 179 SUPERFAMILY SSF47928 3 104 1.29E-17 T 28-03-2018 IPR026015 F1F0 ATP synthase OSCP/delta subunit, N-terminal domain Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CO689_RS02460 23106015b167dbc0d65af2125efbf07e 179 Pfam PF00213 ATP synthase delta (OSCP) subunit 4 174 2.6E-37 T 28-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CO689_RS02460 23106015b167dbc0d65af2125efbf07e 179 PRINTS PR00125 ATP synthase delta subunit signature 150 168 2.8E-19 T 28-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CO689_RS02460 23106015b167dbc0d65af2125efbf07e 179 PRINTS PR00125 ATP synthase delta subunit signature 4 23 2.8E-19 T 28-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CO689_RS02460 23106015b167dbc0d65af2125efbf07e 179 PRINTS PR00125 ATP synthase delta subunit signature 84 98 2.8E-19 T 28-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CO689_RS02460 23106015b167dbc0d65af2125efbf07e 179 PRINTS PR00125 ATP synthase delta subunit signature 73 84 2.8E-19 T 28-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CO689_RS02460 23106015b167dbc0d65af2125efbf07e 179 PRINTS PR00125 ATP synthase delta subunit signature 135 150 2.8E-19 T 28-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CO689_RS02460 23106015b167dbc0d65af2125efbf07e 179 Gene3D G3DSA:1.10.520.20 1 105 5.0E-16 T 28-03-2018 IPR026015 F1F0 ATP synthase OSCP/delta subunit, N-terminal domain Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CO689_RS02460 23106015b167dbc0d65af2125efbf07e 179 Hamap MF_01416 ATP synthase subunit delta [atpD]. 1 177 15.376 T 28-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CO689_RS01415 3111c5cf16314ba3a416aceb1c401aff 462 Hamap MF_00743 Fumarate hydratase class II [fumC]. 3 460 88.864 T 28-03-2018 IPR005677 Fumarate hydratase, class II GO:0004333|GO:0006106|GO:0045239 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 CO689_RS01415 3111c5cf16314ba3a416aceb1c401aff 462 PRINTS PR00145 Argininosuccinate lyase family signature 173 193 3.2E-6 T 28-03-2018 CO689_RS01415 3111c5cf16314ba3a416aceb1c401aff 462 PRINTS PR00145 Argininosuccinate lyase family signature 315 331 3.2E-6 T 28-03-2018 CO689_RS01415 3111c5cf16314ba3a416aceb1c401aff 462 PRINTS PR00145 Argininosuccinate lyase family signature 131 153 3.2E-6 T 28-03-2018 CO689_RS01415 3111c5cf16314ba3a416aceb1c401aff 462 Gene3D G3DSA:1.20.200.10 137 415 8.7E-85 T 28-03-2018 CO689_RS01415 3111c5cf16314ba3a416aceb1c401aff 462 PRINTS PR00149 Fumarate lyase superfamily signature 269 296 4.1E-35 T 28-03-2018 IPR000362 Fumarate lyase family CO689_RS01415 3111c5cf16314ba3a416aceb1c401aff 462 PRINTS PR00149 Fumarate lyase superfamily signature 315 331 4.1E-35 T 28-03-2018 IPR000362 Fumarate lyase family CO689_RS01415 3111c5cf16314ba3a416aceb1c401aff 462 PRINTS PR00149 Fumarate lyase superfamily signature 132 150 4.1E-35 T 28-03-2018 IPR000362 Fumarate lyase family CO689_RS01415 3111c5cf16314ba3a416aceb1c401aff 462 PRINTS PR00149 Fumarate lyase superfamily signature 178 196 4.1E-35 T 28-03-2018 IPR000362 Fumarate lyase family CO689_RS01415 3111c5cf16314ba3a416aceb1c401aff 462 Gene3D G3DSA:1.10.40.30 416 460 2.5E-28 T 28-03-2018 CO689_RS01415 3111c5cf16314ba3a416aceb1c401aff 462 Pfam PF00206 Lyase 11 340 5.1E-112 T 28-03-2018 IPR022761 Fumarate lyase, N-terminal CO689_RS01415 3111c5cf16314ba3a416aceb1c401aff 462 Gene3D G3DSA:1.10.275.10 1 136 4.4E-57 T 28-03-2018 IPR024083 Fumarase/histidase, N-terminal CO689_RS01415 3111c5cf16314ba3a416aceb1c401aff 462 TIGRFAM TIGR00979 fumC_II: fumarate hydratase, class II 3 458 7.1E-225 T 28-03-2018 IPR005677 Fumarate hydratase, class II GO:0004333|GO:0006106|GO:0045239 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 CO689_RS01415 3111c5cf16314ba3a416aceb1c401aff 462 SUPERFAMILY SSF48557 3 458 1.73E-147 T 28-03-2018 IPR008948 L-Aspartase-like GO:0003824 CO689_RS01415 3111c5cf16314ba3a416aceb1c401aff 462 ProSitePatterns PS00163 Fumarate lyases signature. 315 324 - T 28-03-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 CO689_RS01415 3111c5cf16314ba3a416aceb1c401aff 462 Pfam PF10415 Fumarase C C-terminus 406 458 3.4E-27 T 28-03-2018 IPR018951 Fumarase C, C-terminal GO:0006099|GO:0016829 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 CO689_RS06245 0811057267e52fbf178d1084ce54c020 140 Gene3D G3DSA:2.60.120.10 16 140 9.7E-25 T 28-03-2018 IPR014710 RmlC-like jelly roll fold CO689_RS06245 0811057267e52fbf178d1084ce54c020 140 Pfam PF07883 Cupin domain 41 116 5.3E-17 T 28-03-2018 IPR013096 Cupin 2, conserved barrel CO689_RS06245 0811057267e52fbf178d1084ce54c020 140 SUPERFAMILY SSF51182 4 121 2.63E-26 T 28-03-2018 IPR011051 RmlC-like cupin domain CO689_RS10695 32efcce56989020851f8d3b3c82c2c28 105 Gene3D G3DSA:2.60.40.10 28 105 1.0E-12 T 28-03-2018 IPR013783 Immunoglobulin-like fold CO689_RS10695 32efcce56989020851f8d3b3c82c2c28 105 Pfam PF16403 Domain of unknown function (DUF5011) 33 104 3.0E-20 T 28-03-2018 IPR032179 Domain of unknown function DUF5011 CO689_RS13235 d958a61dc04a00d24650cd3257ca71e0 299 TIGRFAM TIGR00436 era: GTP-binding protein Era 7 277 2.8E-105 T 28-03-2018 IPR005662 GTP-binding protein Era GO:0003723|GO:0005525|GO:0005622 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CO689_RS13235 d958a61dc04a00d24650cd3257ca71e0 299 Gene3D G3DSA:3.30.300.20 183 297 3.2E-45 T 28-03-2018 IPR015946 K homology domain-like, alpha/beta CO689_RS13235 d958a61dc04a00d24650cd3257ca71e0 299 Gene3D G3DSA:3.40.50.300 2 54 3.6E-13 T 28-03-2018 CO689_RS13235 d958a61dc04a00d24650cd3257ca71e0 299 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 7 165 8.0E-27 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 CO689_RS13235 d958a61dc04a00d24650cd3257ca71e0 299 SUPERFAMILY SSF52540 5 179 2.02E-47 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CO689_RS13235 d958a61dc04a00d24650cd3257ca71e0 299 Hamap MF_00367 GTPase Era [era]. 4 294 38.65 T 28-03-2018 IPR005662 GTP-binding protein Era GO:0003723|GO:0005525|GO:0005622 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CO689_RS13235 d958a61dc04a00d24650cd3257ca71e0 299 Gene3D G3DSA:3.40.50.300 55 177 2.9E-19 T 28-03-2018 CO689_RS13235 d958a61dc04a00d24650cd3257ca71e0 299 SUPERFAMILY SSF54814 180 294 2.13E-41 T 28-03-2018 IPR009019 K homology domain, prokaryotic type GO:0003723 CO689_RS13235 d958a61dc04a00d24650cd3257ca71e0 299 Pfam PF07650 KH domain 206 283 3.3E-23 T 28-03-2018 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CO689_RS13235 d958a61dc04a00d24650cd3257ca71e0 299 Pfam PF01926 50S ribosome-binding GTPase 9 123 5.4E-25 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CO689_RS02250 04269943e79b2647fa37f90ce38be687 716 Gene3D G3DSA:1.10.10.650 2 102 3.0E-30 T 28-03-2018 IPR023319 Tex-like protein, HTH domain CO689_RS02250 04269943e79b2647fa37f90ce38be687 716 SMART SM00316 641 712 2.6E-20 T 28-03-2018 IPR022967 RNA-binding domain, S1 CO689_RS02250 04269943e79b2647fa37f90ce38be687 716 SUPERFAMILY SSF50249 629 711 1.04E-21 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CO689_RS02250 04269943e79b2647fa37f90ce38be687 716 Gene3D G3DSA:1.10.150.310 488 622 5.9E-45 T 28-03-2018 CO689_RS02250 04269943e79b2647fa37f90ce38be687 716 Pfam PF12836 Helix-hairpin-helix motif 480 544 2.8E-24 T 28-03-2018 CO689_RS02250 04269943e79b2647fa37f90ce38be687 716 Pfam PF16921 Tex protein YqgF-like domain 315 440 2.6E-53 T 28-03-2018 IPR032639 Tex protein, YqgF-like domain CO689_RS02250 04269943e79b2647fa37f90ce38be687 716 Pfam PF09371 Tex-like protein N-terminal domain 9 191 4.3E-63 T 28-03-2018 IPR018974 Tex-like protein, N-terminal CO689_RS02250 04269943e79b2647fa37f90ce38be687 716 SMART SM00732 315 413 1.4E-33 T 28-03-2018 IPR006641 YqgF/RNase H-like domain GO:0006139 CO689_RS02250 04269943e79b2647fa37f90ce38be687 716 SUPERFAMILY SSF47781 459 545 1.03E-25 T 28-03-2018 IPR010994 RuvA domain 2-like CO689_RS02250 04269943e79b2647fa37f90ce38be687 716 Gene3D G3DSA:1.10.3500.10 103 343 5.6E-84 T 28-03-2018 IPR023323 Tex-like domain CO689_RS02250 04269943e79b2647fa37f90ce38be687 716 SUPERFAMILY SSF158832 3 310 8.24E-106 T 28-03-2018 CO689_RS02250 04269943e79b2647fa37f90ce38be687 716 Gene3D G3DSA:1.10.3500.10 344 487 2.2E-39 T 28-03-2018 IPR023323 Tex-like domain CO689_RS02250 04269943e79b2647fa37f90ce38be687 716 SUPERFAMILY SSF47781 549 624 4.67E-17 T 28-03-2018 IPR010994 RuvA domain 2-like CO689_RS02250 04269943e79b2647fa37f90ce38be687 716 SUPERFAMILY SSF53098 311 458 4.1E-48 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CO689_RS02250 04269943e79b2647fa37f90ce38be687 716 Pfam PF00575 S1 RNA binding domain 641 711 4.8E-15 T 28-03-2018 IPR003029 S1 domain GO:0003676 CO689_RS02250 04269943e79b2647fa37f90ce38be687 716 Gene3D G3DSA:2.40.50.140 632 714 1.2E-21 T 28-03-2018 CO689_RS12345 5d26b6a0b7058775685739cba84b024c 219 Pfam PF00697 N-(5'phosphoribosyl)anthranilate (PRA) isomerase 4 199 1.6E-36 T 28-03-2018 IPR001240 N-(5'phosphoribosyl) anthranilate isomerase (PRAI) GO:0004640|GO:0006568 KEGG: 00400+5.3.1.24 CO689_RS12345 5d26b6a0b7058775685739cba84b024c 219 Gene3D G3DSA:3.20.20.70 3 200 5.5E-50 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CO689_RS12345 5d26b6a0b7058775685739cba84b024c 219 SUPERFAMILY SSF51366 1 203 1.19E-44 T 28-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 CO689_RS12345 5d26b6a0b7058775685739cba84b024c 219 Hamap MF_00135 N-(5'-phosphoribosyl)anthranilate isomerase [trpF]. 1 206 31.477 T 28-03-2018 IPR001240 N-(5'phosphoribosyl) anthranilate isomerase (PRAI) GO:0004640|GO:0006568 KEGG: 00400+5.3.1.24 CO689_RS13160 0432d1857d844ab1cb3fc013917b8116 686 Gene3D G3DSA:3.90.1310.10 34 319 6.9E-37 T 28-03-2018 CO689_RS13160 0432d1857d844ab1cb3fc013917b8116 686 Gene3D G3DSA:3.40.710.10 320 686 4.6E-69 T 28-03-2018 CO689_RS13160 0432d1857d844ab1cb3fc013917b8116 686 Pfam PF00905 Penicillin binding protein transpeptidase domain 351 656 1.8E-60 T 28-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 CO689_RS13160 0432d1857d844ab1cb3fc013917b8116 686 Pfam PF03717 Penicillin-binding Protein dimerisation domain 66 303 1.0E-38 T 28-03-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 CO689_RS13160 0432d1857d844ab1cb3fc013917b8116 686 SUPERFAMILY SSF56601 320 676 4.77E-59 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CO689_RS13160 0432d1857d844ab1cb3fc013917b8116 686 SUPERFAMILY SSF56519 62 123 1.83E-36 T 28-03-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 CO689_RS13160 0432d1857d844ab1cb3fc013917b8116 686 SUPERFAMILY SSF56519 189 319 1.83E-36 T 28-03-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 CO689_RS06985 8cb7adda6ab119f8ec7841c7f68dd440 428 SUPERFAMILY SSF55681 117 418 3.8E-100 T 28-03-2018 CO689_RS06985 8cb7adda6ab119f8ec7841c7f68dd440 428 Gene3D G3DSA:3.30.930.10 106 428 4.1E-95 T 28-03-2018 CO689_RS06985 8cb7adda6ab119f8ec7841c7f68dd440 428 SUPERFAMILY SSF46589 1 113 7.32E-30 T 28-03-2018 IPR010978 tRNA-binding arm GO:0000166 CO689_RS06985 8cb7adda6ab119f8ec7841c7f68dd440 428 Gene3D G3DSA:1.10.287.40 2 105 3.3E-27 T 28-03-2018 CO689_RS06985 8cb7adda6ab119f8ec7841c7f68dd440 428 Hamap MF_00176 Serine--tRNA ligase [serS]. 1 422 42.562 T 28-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 CO689_RS06985 8cb7adda6ab119f8ec7841c7f68dd440 428 TIGRFAM TIGR00414 serS: serine--tRNA ligase 1 417 4.1E-172 T 28-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 CO689_RS06985 8cb7adda6ab119f8ec7841c7f68dd440 428 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 223 400 3.3E-32 T 28-03-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 CO689_RS06985 8cb7adda6ab119f8ec7841c7f68dd440 428 PRINTS PR00981 Seryl-tRNA synthetase signature 264 276 4.1E-33 T 28-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 CO689_RS06985 8cb7adda6ab119f8ec7841c7f68dd440 428 PRINTS PR00981 Seryl-tRNA synthetase signature 276 289 4.1E-33 T 28-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 CO689_RS06985 8cb7adda6ab119f8ec7841c7f68dd440 428 PRINTS PR00981 Seryl-tRNA synthetase signature 351 367 4.1E-33 T 28-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 CO689_RS06985 8cb7adda6ab119f8ec7841c7f68dd440 428 PRINTS PR00981 Seryl-tRNA synthetase signature 333 349 4.1E-33 T 28-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 CO689_RS06985 8cb7adda6ab119f8ec7841c7f68dd440 428 PRINTS PR00981 Seryl-tRNA synthetase signature 316 329 4.1E-33 T 28-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 CO689_RS06985 8cb7adda6ab119f8ec7841c7f68dd440 428 PIRSF PIRSF001529 1 426 1.7E-193 T 28-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 CO689_RS06985 8cb7adda6ab119f8ec7841c7f68dd440 428 Pfam PF02403 Seryl-tRNA synthetase N-terminal domain 1 107 2.2E-31 T 28-03-2018 IPR015866 Serine-tRNA synthetase, type1, N-terminal KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281|Reactome: R-HSA-2408557|Reactome: R-HSA-379716 CO689_RS06525 a4883e29307341466e5beb11877c5c9e 311 PIRSF PIRSF036894 1 311 1.9E-127 T 28-03-2018 IPR014628 Mannose-6-phosphate isomerase, Firmicutes type, short form GO:0004476|GO:0005975 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882 CO689_RS06525 a4883e29307341466e5beb11877c5c9e 311 SUPERFAMILY SSF51182 2 309 1.2E-99 T 28-03-2018 IPR011051 RmlC-like cupin domain CO689_RS06525 a4883e29307341466e5beb11877c5c9e 311 Gene3D G3DSA:2.60.120.10 1 150 3.4E-35 T 28-03-2018 IPR014710 RmlC-like jelly roll fold CO689_RS06525 a4883e29307341466e5beb11877c5c9e 311 Gene3D G3DSA:2.60.120.10 151 219 6.0E-22 T 28-03-2018 IPR014710 RmlC-like jelly roll fold CO689_RS06525 a4883e29307341466e5beb11877c5c9e 311 TIGRFAM TIGR00218 manA: mannose-6-phosphate isomerase, class I 99 310 2.6E-40 T 28-03-2018 IPR001250 Mannose-6-phosphate isomerase, type I GO:0004476|GO:0005975|GO:0008270 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-446205 CO689_RS06525 a4883e29307341466e5beb11877c5c9e 311 Pfam PF01238 Phosphomannose isomerase type I 3 310 5.5E-36 T 28-03-2018 IPR001250 Mannose-6-phosphate isomerase, type I GO:0004476|GO:0005975|GO:0008270 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-446205 CO689_RS06525 a4883e29307341466e5beb11877c5c9e 311 Gene3D G3DSA:2.60.120.10 232 311 9.9E-14 T 28-03-2018 IPR014710 RmlC-like jelly roll fold CO689_RS07695 05c5a289a1f48643aff34b99c813efdc 284 Pfam PF00288 GHMP kinases N terminal domain 86 142 3.9E-11 T 28-03-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 CO689_RS07695 05c5a289a1f48643aff34b99c813efdc 284 Hamap MF_00061 Putative 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase [ispE]. 2 280 33.41 T 28-03-2018 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00710+2.7.1.14|KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 CO689_RS07695 05c5a289a1f48643aff34b99c813efdc 284 TIGRFAM TIGR00154 ispE: 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase 3 284 2.1E-92 T 28-03-2018 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00710+2.7.1.14|KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 CO689_RS07695 05c5a289a1f48643aff34b99c813efdc 284 Gene3D G3DSA:3.30.70.890 160 282 2.5E-26 T 28-03-2018 IPR013750 GHMP kinase, C-terminal domain CO689_RS07695 05c5a289a1f48643aff34b99c813efdc 284 SUPERFAMILY SSF55060 160 282 1.37E-29 T 28-03-2018 IPR013750 GHMP kinase, C-terminal domain CO689_RS07695 05c5a289a1f48643aff34b99c813efdc 284 Pfam PF08544 GHMP kinases C terminal 199 270 9.4E-8 T 28-03-2018 IPR013750 GHMP kinase, C-terminal domain CO689_RS07695 05c5a289a1f48643aff34b99c813efdc 284 SUPERFAMILY SSF54211 1 155 7.13E-44 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CO689_RS07695 05c5a289a1f48643aff34b99c813efdc 284 PIRSF PIRSF010376 1 283 5.2E-91 T 28-03-2018 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00710+2.7.1.14|KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 CO689_RS07695 05c5a289a1f48643aff34b99c813efdc 284 Gene3D G3DSA:3.30.230.10 2 158 1.7E-47 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CO689_RS12190 90766c2c8807dea56482c1400e34d8ca 80 SUPERFAMILY SSF47473 39 78 4.78E-5 T 28-03-2018 IPR011992 EF-hand domain pair CO689_RS12190 90766c2c8807dea56482c1400e34d8ca 80 Hamap MF_00363 UPF0154 protein . 6 76 22.848 T 28-03-2018 IPR005359 Protein with unknown function UPF0154 CO689_RS12190 90766c2c8807dea56482c1400e34d8ca 80 Gene3D G3DSA:1.10.238.10 39 80 1.3E-4 T 28-03-2018 CO689_RS12190 90766c2c8807dea56482c1400e34d8ca 80 Pfam PF03672 Uncharacterised protein family (UPF0154) 14 73 1.9E-31 T 28-03-2018 IPR005359 Protein with unknown function UPF0154 CO689_RS12190 90766c2c8807dea56482c1400e34d8ca 80 ProDom PD048972 UPF0154 TRANSMEMBRANE MEMBRANE UNCHARACTERIZED FAMILY YNEF SUPERFAMILY MG335.1 EXPORTED MYCGA5700 5 66 2.0E-16 T 28-03-2018 IPR005359 Protein with unknown function UPF0154 CO689_RS11705 932add1fda74ce1065b42a920650404d 427 SMART SM00228 179 256 0.0026 T 28-03-2018 IPR001478 PDZ domain GO:0005515 CO689_RS11705 932add1fda74ce1065b42a920650404d 427 Gene3D G3DSA:2.30.42.10 145 269 7.8E-16 T 28-03-2018 CO689_RS11705 932add1fda74ce1065b42a920650404d 427 Pfam PF02163 Peptidase family M50 8 412 6.9E-76 T 28-03-2018 IPR008915 Peptidase M50 GO:0004222|GO:0006508 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889|Reactome: R-MMU-8963889 CO689_RS11705 932add1fda74ce1065b42a920650404d 427 TIGRFAM TIGR00054 TIGR00054: RIP metalloprotease RseP 2 426 1.0E-86 T 28-03-2018 IPR004387 Peptidase M50, putative membrane-associated zinc metallopeptidase GO:0004222|GO:0006508|GO:0016021 CO689_RS11705 932add1fda74ce1065b42a920650404d 427 Pfam PF13180 PDZ domain 189 262 2.3E-11 T 28-03-2018 IPR001478 PDZ domain GO:0005515 CO689_RS11705 932add1fda74ce1065b42a920650404d 427 SUPERFAMILY SSF50156 174 263 1.22E-16 T 28-03-2018 IPR001478 PDZ domain GO:0005515 CO689_RS13400 d16c7586119735f6ebdc3bb2dfd5dc15 208 Hamap MF_00551 Uridine kinase [udk]. 1 205 41.428 T 28-03-2018 IPR026008 Uridine kinase GO:0004849|GO:0005524|GO:0016773 KEGG: 00240+2.7.1.48|KEGG: 00983+2.7.1.48|MetaCyc: PWY-7193 CO689_RS13400 d16c7586119735f6ebdc3bb2dfd5dc15 208 TIGRFAM TIGR00235 udk: uridine kinase 3 204 1.4E-89 T 28-03-2018 IPR000764 Uridine kinase-like KEGG: 00240+2.7.1.48|KEGG: 00983+2.7.1.48|MetaCyc: PWY-7193|Reactome: R-HSA-73614 CO689_RS13400 d16c7586119735f6ebdc3bb2dfd5dc15 208 Gene3D G3DSA:3.40.50.300 1 208 1.3E-59 T 28-03-2018 CO689_RS13400 d16c7586119735f6ebdc3bb2dfd5dc15 208 Pfam PF00485 Phosphoribulokinase / Uridine kinase family 6 191 1.9E-46 T 28-03-2018 IPR006083 Phosphoribulokinase/uridine kinase GO:0005524|GO:0008152|GO:0016301 Reactome: R-HSA-73614 CO689_RS13400 d16c7586119735f6ebdc3bb2dfd5dc15 208 SUPERFAMILY SSF52540 5 196 1.99E-51 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CO689_RS13400 d16c7586119735f6ebdc3bb2dfd5dc15 208 PRINTS PR00988 Uridine kinase signature 34 45 2.7E-38 T 28-03-2018 CO689_RS13400 d16c7586119735f6ebdc3bb2dfd5dc15 208 PRINTS PR00988 Uridine kinase signature 171 184 2.7E-38 T 28-03-2018 CO689_RS13400 d16c7586119735f6ebdc3bb2dfd5dc15 208 PRINTS PR00988 Uridine kinase signature 4 21 2.7E-38 T 28-03-2018 CO689_RS13400 d16c7586119735f6ebdc3bb2dfd5dc15 208 PRINTS PR00988 Uridine kinase signature 79 94 2.7E-38 T 28-03-2018 CO689_RS13400 d16c7586119735f6ebdc3bb2dfd5dc15 208 PRINTS PR00988 Uridine kinase signature 135 145 2.7E-38 T 28-03-2018 CO689_RS13400 d16c7586119735f6ebdc3bb2dfd5dc15 208 PRINTS PR00988 Uridine kinase signature 149 160 2.7E-38 T 28-03-2018 CO689_RS06400 d7e9263525f5401a2620fd10ac60e2ea 139 SUPERFAMILY SSF46785 3 134 2.29E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS06400 d7e9263525f5401a2620fd10ac60e2ea 139 Gene3D G3DSA:1.10.10.10 1 138 2.7E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS06400 d7e9263525f5401a2620fd10ac60e2ea 139 Pfam PF02082 Transcriptional regulator 4 78 1.8E-16 T 28-03-2018 IPR000944 Transcription regulator Rrf2-type CO689_RS11350 2503f3f3e9ec334281214168b59446e1 1057 Pfam PF02142 MGS-like domain 949 1035 1.9E-19 T 28-03-2018 IPR011607 Methylglyoxal synthase-like domain CO689_RS11350 2503f3f3e9ec334281214168b59446e1 1057 TIGRFAM TIGR01369 CPSaseII_lrg: carbamoyl-phosphate synthase, large subunit 3 1045 0.0 T 28-03-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CO689_RS11350 2503f3f3e9ec334281214168b59446e1 1057 SUPERFAMILY SSF52440 1 127 3.88E-48 T 28-03-2018 IPR016185 Pre-ATP-grasp domain CO689_RS11350 2503f3f3e9ec334281214168b59446e1 1057 Gene3D G3DSA:3.30.1490.20 648 736 8.4E-24 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CO689_RS11350 2503f3f3e9ec334281214168b59446e1 1057 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 296 303 - T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CO689_RS11350 2503f3f3e9ec334281214168b59446e1 1057 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 128 333 8.2E-80 T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CO689_RS11350 2503f3f3e9ec334281214168b59446e1 1057 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 666 866 2.4E-40 T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CO689_RS11350 2503f3f3e9ec334281214168b59446e1 1057 Gene3D G3DSA:3.40.50.20 4 128 3.1E-37 T 28-03-2018 CO689_RS11350 2503f3f3e9ec334281214168b59446e1 1057 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 702 716 - T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CO689_RS11350 2503f3f3e9ec334281214168b59446e1 1057 Gene3D G3DSA:3.40.50.1380 921 1048 3.1E-36 T 28-03-2018 IPR011607 Methylglyoxal synthase-like domain CO689_RS11350 2503f3f3e9ec334281214168b59446e1 1057 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 830 837 - T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CO689_RS11350 2503f3f3e9ec334281214168b59446e1 1057 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 19 33 2.5E-64 T 28-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CO689_RS11350 2503f3f3e9ec334281214168b59446e1 1057 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 204 223 2.5E-64 T 28-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CO689_RS11350 2503f3f3e9ec334281214168b59446e1 1057 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 296 325 2.5E-64 T 28-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CO689_RS11350 2503f3f3e9ec334281214168b59446e1 1057 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 48 58 2.5E-64 T 28-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CO689_RS11350 2503f3f3e9ec334281214168b59446e1 1057 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 168 180 2.5E-64 T 28-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CO689_RS11350 2503f3f3e9ec334281214168b59446e1 1057 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 378 396 2.5E-64 T 28-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CO689_RS11350 2503f3f3e9ec334281214168b59446e1 1057 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 239 256 2.5E-64 T 28-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CO689_RS11350 2503f3f3e9ec334281214168b59446e1 1057 SUPERFAMILY SSF52335 935 1051 8.77E-34 T 28-03-2018 IPR011607 Methylglyoxal synthase-like domain CO689_RS11350 2503f3f3e9ec334281214168b59446e1 1057 SMART SM00851 949 1035 1.5E-25 T 28-03-2018 IPR011607 Methylglyoxal synthase-like domain CO689_RS11350 2503f3f3e9ec334281214168b59446e1 1057 Hamap MF_01210_A Carbamoyl-phosphate synthase large chain [carB]. 5 1057 13.436 T 28-03-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CO689_RS11350 2503f3f3e9ec334281214168b59446e1 1057 Hamap MF_01210_B Carbamoyl-phosphate synthase large chain [carB]. 1 1056 13.088 T 28-03-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CO689_RS11350 2503f3f3e9ec334281214168b59446e1 1057 SMART SM01096 420 540 1.1E-64 T 28-03-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CO689_RS11350 2503f3f3e9ec334281214168b59446e1 1057 SUPERFAMILY SSF52440 549 668 2.88E-48 T 28-03-2018 IPR016185 Pre-ATP-grasp domain CO689_RS11350 2503f3f3e9ec334281214168b59446e1 1057 SUPERFAMILY SSF56059 666 927 2.65E-101 T 28-03-2018 CO689_RS11350 2503f3f3e9ec334281214168b59446e1 1057 SUPERFAMILY SSF56059 128 399 5.3E-106 T 28-03-2018 CO689_RS11350 2503f3f3e9ec334281214168b59446e1 1057 Pfam PF02787 Carbamoyl-phosphate synthetase large chain, oligomerisation domain 423 540 8.2E-41 T 28-03-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CO689_RS11350 2503f3f3e9ec334281214168b59446e1 1057 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 164 178 - T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CO689_RS11350 2503f3f3e9ec334281214168b59446e1 1057 Gene3D G3DSA:1.10.1030.10 405 531 9.9E-48 T 28-03-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CO689_RS11350 2503f3f3e9ec334281214168b59446e1 1057 Gene3D G3DSA:3.40.50.20 532 647 1.8E-59 T 28-03-2018 CO689_RS11350 2503f3f3e9ec334281214168b59446e1 1057 Gene3D G3DSA:3.30.470.20 129 401 4.1E-63 T 28-03-2018 CO689_RS11350 2503f3f3e9ec334281214168b59446e1 1057 SUPERFAMILY SSF48108 395 546 3.92E-51 T 28-03-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CO689_RS11350 2503f3f3e9ec334281214168b59446e1 1057 SMART SM01209 672 836 3.5E-4 T 28-03-2018 CO689_RS11350 2503f3f3e9ec334281214168b59446e1 1057 Gene3D G3DSA:3.30.470.20 737 920 4.8E-42 T 28-03-2018 CO689_RS11790 6a76dd6e40a9ebba46214dee19871565 303 Pfam PF16198 tRNA pseudouridylate synthase B C-terminal domain 178 236 2.6E-13 T 28-03-2018 IPR032819 tRNA pseudouridylate synthase B, C-terminal Reactome: R-HSA-171319|Reactome: R-HSA-6790901 CO689_RS11790 6a76dd6e40a9ebba46214dee19871565 303 Pfam PF01509 TruB family pseudouridylate synthase (N terminal domain) 23 177 1.3E-54 T 28-03-2018 IPR002501 Pseudouridine synthase II, N-terminal GO:0006396 CO689_RS11790 6a76dd6e40a9ebba46214dee19871565 303 Gene3D G3DSA:3.30.2350.10 1 227 7.4E-80 T 28-03-2018 CO689_RS11790 6a76dd6e40a9ebba46214dee19871565 303 TIGRFAM TIGR00431 TruB: tRNA pseudouridine(55) synthase 1 215 7.7E-78 T 28-03-2018 IPR014780 tRNA pseudouridine synthase II, TruB GO:0001522|GO:0003723|GO:0009451|GO:0009982 CO689_RS11790 6a76dd6e40a9ebba46214dee19871565 303 SUPERFAMILY SSF55120 1 226 7.48E-77 T 28-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 CO689_RS11790 6a76dd6e40a9ebba46214dee19871565 303 Hamap MF_01080 tRNA pseudouridine synthase B [truB]. 1 302 18.662 T 28-03-2018 IPR014780 tRNA pseudouridine synthase II, TruB GO:0001522|GO:0003723|GO:0009451|GO:0009982 CO689_RS13490 c8470763dd72f941d0cd27353c6e7688 588 SUPERFAMILY SSF55681 118 298 9.96E-113 T 28-03-2018 CO689_RS13490 c8470763dd72f941d0cd27353c6e7688 588 SUPERFAMILY SSF55681 427 587 9.96E-113 T 28-03-2018 CO689_RS13490 c8470763dd72f941d0cd27353c6e7688 588 SUPERFAMILY SSF50249 3 112 9.9E-34 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CO689_RS13490 c8470763dd72f941d0cd27353c6e7688 588 Gene3D G3DSA:3.30.930.10 137 358 7.9E-57 T 28-03-2018 CO689_RS13490 c8470763dd72f941d0cd27353c6e7688 588 Gene3D G3DSA:3.30.930.10 370 588 2.7E-56 T 28-03-2018 CO689_RS13490 c8470763dd72f941d0cd27353c6e7688 588 Pfam PF00152 tRNA synthetases class II (D, K and N) 123 560 2.0E-113 T 28-03-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 CO689_RS13490 c8470763dd72f941d0cd27353c6e7688 588 Pfam PF02938 GAD domain 314 408 7.1E-30 T 28-03-2018 IPR029351 GAD domain Reactome: R-HSA-379726 CO689_RS13490 c8470763dd72f941d0cd27353c6e7688 588 Gene3D G3DSA:2.40.50.140 1 111 7.3E-29 T 28-03-2018 CO689_RS13490 c8470763dd72f941d0cd27353c6e7688 588 Hamap MF_00044 Aspartate--tRNA(Asp/Asn) ligase [aspS]. 3 587 35.281 T 28-03-2018 IPR004524 Aspartate-tRNA ligase, type 1 GO:0005524|GO:0016874 Reactome: R-HSA-379726 CO689_RS13490 c8470763dd72f941d0cd27353c6e7688 588 SUPERFAMILY SSF55261 295 422 1.54E-40 T 28-03-2018 IPR004115 GAD-like domain GO:0004812|GO:0005524|GO:0005737 Reactome: R-HSA-379726 CO689_RS13490 c8470763dd72f941d0cd27353c6e7688 588 PRINTS PR01042 Aspartyl-tRNA synthetase signature 196 208 5.8E-27 T 28-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 CO689_RS13490 c8470763dd72f941d0cd27353c6e7688 588 PRINTS PR01042 Aspartyl-tRNA synthetase signature 521 535 5.8E-27 T 28-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 CO689_RS13490 c8470763dd72f941d0cd27353c6e7688 588 PRINTS PR01042 Aspartyl-tRNA synthetase signature 213 226 5.8E-27 T 28-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 CO689_RS13490 c8470763dd72f941d0cd27353c6e7688 588 PRINTS PR01042 Aspartyl-tRNA synthetase signature 477 493 5.8E-27 T 28-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 CO689_RS13490 c8470763dd72f941d0cd27353c6e7688 588 Pfam PF01336 OB-fold nucleic acid binding domain 20 105 2.5E-18 T 28-03-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 CO689_RS13490 c8470763dd72f941d0cd27353c6e7688 588 TIGRFAM TIGR00459 aspS_bact: aspartate--tRNA ligase 3 585 3.6E-254 T 28-03-2018 IPR004524 Aspartate-tRNA ligase, type 1 GO:0005524|GO:0016874 Reactome: R-HSA-379726 CO689_RS04130 29d7bb64a7ab502f3f8288c1de38dfc2 180 ProSitePatterns PS01081 TetR-type HTH domain signature. 26 57 - T 28-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site CO689_RS04130 29d7bb64a7ab502f3f8288c1de38dfc2 180 SUPERFAMILY SSF48498 73 179 2.45E-9 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CO689_RS04130 29d7bb64a7ab502f3f8288c1de38dfc2 180 Gene3D G3DSA:1.10.260.40 44 162 4.3E-4 T 28-03-2018 CO689_RS04130 29d7bb64a7ab502f3f8288c1de38dfc2 180 SUPERFAMILY SSF46689 12 63 2.57E-9 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CO689_RS04130 29d7bb64a7ab502f3f8288c1de38dfc2 180 Pfam PF00440 Bacterial regulatory proteins, tetR family 21 58 8.6E-7 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CO689_RS04130 29d7bb64a7ab502f3f8288c1de38dfc2 180 Gene3D G3DSA:1.10.10.60 4 43 1.9E-7 T 28-03-2018 CO689_RS05195 a42f18e5294c7a7dcc5273e101997730 286 Gene3D G3DSA:3.40.50.10490 81 276 8.1E-36 T 28-03-2018 CO689_RS05195 a42f18e5294c7a7dcc5273e101997730 286 Gene3D G3DSA:1.10.10.10 2 80 6.0E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS05195 a42f18e5294c7a7dcc5273e101997730 286 SUPERFAMILY SSF53697 100 280 1.05E-35 T 28-03-2018 CO689_RS05195 a42f18e5294c7a7dcc5273e101997730 286 SUPERFAMILY SSF46689 6 80 4.12E-17 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CO689_RS05195 a42f18e5294c7a7dcc5273e101997730 286 Pfam PF01380 SIS domain 127 257 2.3E-21 T 28-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 CO689_RS05195 a42f18e5294c7a7dcc5273e101997730 286 Pfam PF01418 Helix-turn-helix domain, rpiR family 5 77 1.1E-15 T 28-03-2018 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 CO689_RS04235 3054debe807fa62504e765925edc7c07 228 SUPERFAMILY SSF46785 10 80 5.05E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS04235 3054debe807fa62504e765925edc7c07 228 SUPERFAMILY SSF48008 83 221 1.7E-16 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CO689_RS04235 3054debe807fa62504e765925edc7c07 228 SMART SM00895 86 215 3.8E-6 T 28-03-2018 IPR011711 GntR, C-terminal CO689_RS04235 3054debe807fa62504e765925edc7c07 228 SMART SM00345 19 77 1.5E-10 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CO689_RS04235 3054debe807fa62504e765925edc7c07 228 Gene3D G3DSA:1.10.10.10 11 73 1.3E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS04235 3054debe807fa62504e765925edc7c07 228 Pfam PF00392 Bacterial regulatory proteins, gntR family 16 72 5.8E-14 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CO689_RS04235 3054debe807fa62504e765925edc7c07 228 Gene3D G3DSA:1.20.120.530 74 228 4.8E-16 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CO689_RS04235 3054debe807fa62504e765925edc7c07 228 Pfam PF07729 FCD domain 86 211 8.8E-15 T 28-03-2018 IPR011711 GntR, C-terminal CO689_RS08070 49a7398c37a61c9c4df882963ecc70a4 693 Gene3D G3DSA:2.40.30.10 286 399 2.7E-29 T 28-03-2018 CO689_RS08070 49a7398c37a61c9c4df882963ecc70a4 693 SUPERFAMILY SSF54980 602 689 4.8E-31 T 28-03-2018 IPR035647 EF-G domain III/V-like CO689_RS08070 49a7398c37a61c9c4df882963ecc70a4 693 Pfam PF00679 Elongation factor G C-terminus 599 685 1.6E-30 T 28-03-2018 IPR000640 Elongation factor EFG, domain V-like CO689_RS08070 49a7398c37a61c9c4df882963ecc70a4 693 PRINTS PR00315 GTP-binding elongation factor signature 58 66 1.5E-16 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CO689_RS08070 49a7398c37a61c9c4df882963ecc70a4 693 PRINTS PR00315 GTP-binding elongation factor signature 78 88 1.5E-16 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CO689_RS08070 49a7398c37a61c9c4df882963ecc70a4 693 PRINTS PR00315 GTP-binding elongation factor signature 94 105 1.5E-16 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CO689_RS08070 49a7398c37a61c9c4df882963ecc70a4 693 PRINTS PR00315 GTP-binding elongation factor signature 130 139 1.5E-16 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CO689_RS08070 49a7398c37a61c9c4df882963ecc70a4 693 PRINTS PR00315 GTP-binding elongation factor signature 12 25 1.5E-16 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CO689_RS08070 49a7398c37a61c9c4df882963ecc70a4 693 SMART SM00889 479 597 1.5E-69 T 28-03-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 CO689_RS08070 49a7398c37a61c9c4df882963ecc70a4 693 SUPERFAMILY SSF54980 403 480 3.96E-25 T 28-03-2018 IPR035647 EF-G domain III/V-like CO689_RS08070 49a7398c37a61c9c4df882963ecc70a4 693 Pfam PF00009 Elongation factor Tu GTP binding domain 9 280 6.0E-69 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CO689_RS08070 49a7398c37a61c9c4df882963ecc70a4 693 TIGRFAM TIGR00484 EF-G: translation elongation factor G 1 691 0.0 T 28-03-2018 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CO689_RS08070 49a7398c37a61c9c4df882963ecc70a4 693 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 51 66 - T 28-03-2018 IPR031157 Tr-type G domain, conserved site CO689_RS08070 49a7398c37a61c9c4df882963ecc70a4 693 Gene3D G3DSA:3.30.70.240 613 690 3.1E-32 T 28-03-2018 CO689_RS08070 49a7398c37a61c9c4df882963ecc70a4 693 Gene3D G3DSA:3.30.230.10 491 612 2.2E-44 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CO689_RS08070 49a7398c37a61c9c4df882963ecc70a4 693 Pfam PF03144 Elongation factor Tu domain 2 323 390 3.7E-13 T 28-03-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 CO689_RS08070 49a7398c37a61c9c4df882963ecc70a4 693 SUPERFAMILY SSF50447 263 403 1.77E-33 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain CO689_RS08070 49a7398c37a61c9c4df882963ecc70a4 693 Hamap MF_00054_B Elongation factor G [fusA]. 6 690 108.114 T 28-03-2018 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CO689_RS08070 49a7398c37a61c9c4df882963ecc70a4 693 SUPERFAMILY SSF54211 478 598 3.79E-42 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CO689_RS08070 49a7398c37a61c9c4df882963ecc70a4 693 SMART SM00838 599 686 4.5E-56 T 28-03-2018 IPR000640 Elongation factor EFG, domain V-like CO689_RS08070 49a7398c37a61c9c4df882963ecc70a4 693 SUPERFAMILY SSF52540 6 280 2.78E-109 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CO689_RS08070 49a7398c37a61c9c4df882963ecc70a4 693 Gene3D G3DSA:3.40.50.300 1 285 5.9E-64 T 28-03-2018 CO689_RS08070 49a7398c37a61c9c4df882963ecc70a4 693 Pfam PF03764 Elongation factor G, domain IV 478 596 4.7E-45 T 28-03-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 CO689_RS08070 49a7398c37a61c9c4df882963ecc70a4 693 Gene3D G3DSA:3.30.70.870 400 490 1.8E-33 T 28-03-2018 CO689_RS08070 49a7398c37a61c9c4df882963ecc70a4 693 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 9 179 1.4E-42 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 CO689_RS08070 49a7398c37a61c9c4df882963ecc70a4 693 Pfam PF14492 Elongation Factor G, domain II 403 476 4.5E-33 T 28-03-2018 CO689_RS03020 d41445c8cc5dcc157b1f3c96a5930ddb 314 Gene3D G3DSA:1.10.150.20 241 314 9.4E-26 T 28-03-2018 CO689_RS03020 d41445c8cc5dcc157b1f3c96a5930ddb 314 TIGRFAM TIGR02027 rpoA: DNA-directed RNA polymerase, alpha subunit 21 312 3.0E-118 T 28-03-2018 IPR011773 DNA-directed RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CO689_RS03020 d41445c8cc5dcc157b1f3c96a5930ddb 314 Pfam PF01000 RNA polymerase Rpb3/RpoA insert domain 59 152 6.8E-23 T 28-03-2018 IPR011262 DNA-directed RNA polymerase, insert domain GO:0003899|GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CO689_RS03020 d41445c8cc5dcc157b1f3c96a5930ddb 314 SMART SM00662 20 227 9.7E-100 T 28-03-2018 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CO689_RS03020 d41445c8cc5dcc157b1f3c96a5930ddb 314 SUPERFAMILY SSF47789 247 312 7.06E-23 T 28-03-2018 CO689_RS03020 d41445c8cc5dcc157b1f3c96a5930ddb 314 SUPERFAMILY SSF55257 172 226 2.22E-31 T 28-03-2018 IPR009025 DNA-directed RNA polymerase, RBP11-like dimerisation domain GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CO689_RS03020 d41445c8cc5dcc157b1f3c96a5930ddb 314 SUPERFAMILY SSF55257 8 50 2.22E-31 T 28-03-2018 IPR009025 DNA-directed RNA polymerase, RBP11-like dimerisation domain GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CO689_RS03020 d41445c8cc5dcc157b1f3c96a5930ddb 314 Hamap MF_00059 DNA-directed RNA polymerase subunit alpha [rpoA]. 1 313 35.826 T 28-03-2018 IPR011773 DNA-directed RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CO689_RS03020 d41445c8cc5dcc157b1f3c96a5930ddb 314 Gene3D G3DSA:3.30.1360.10 1 86 6.2E-17 T 28-03-2018 CO689_RS03020 d41445c8cc5dcc157b1f3c96a5930ddb 314 Gene3D G3DSA:3.30.1360.10 107 224 2.3E-27 T 28-03-2018 CO689_RS03020 d41445c8cc5dcc157b1f3c96a5930ddb 314 Pfam PF01193 RNA polymerase Rpb3/Rpb11 dimerisation domain 26 221 1.2E-23 T 28-03-2018 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CO689_RS03020 d41445c8cc5dcc157b1f3c96a5930ddb 314 SUPERFAMILY SSF56553 50 171 9.29E-39 T 28-03-2018 IPR011262 DNA-directed RNA polymerase, insert domain GO:0003899|GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CO689_RS03020 d41445c8cc5dcc157b1f3c96a5930ddb 314 Pfam PF03118 Bacterial RNA polymerase, alpha chain C terminal domain 240 304 2.2E-28 T 28-03-2018 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CO689_RS03020 d41445c8cc5dcc157b1f3c96a5930ddb 314 ProDom PD001179 RNA POLYMERASE ALPHA DNA-DIRECTED SUBUNIT CHAIN NUCLEOTIDYLTRANSFERASE TRANSFERASE TRANSCRIPTION TRANSCRIPTASE 253 314 2.0E-23 T 28-03-2018 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CO689_RS05915 f1185f3b3b8ace46a47a9da264ecf1cf 393 Pfam PF06779 Uncharacterised MFS-type transporter YbfB 18 378 3.5E-75 T 28-03-2018 IPR010645 Uncharacterised MFS-type transporter YbfB CO689_RS05915 f1185f3b3b8ace46a47a9da264ecf1cf 393 SUPERFAMILY SSF103473 4 386 4.58E-39 T 28-03-2018 IPR020846 Major facilitator superfamily domain CO689_RS05915 f1185f3b3b8ace46a47a9da264ecf1cf 393 Gene3D G3DSA:1.20.1250.20 2 196 6.5E-22 T 28-03-2018 CO689_RS05915 f1185f3b3b8ace46a47a9da264ecf1cf 393 Gene3D G3DSA:1.20.1250.20 197 388 4.7E-14 T 28-03-2018 CO689_RS09030 d7ff61b27b13f30a7bae4cb83a026d35 175 Gene3D G3DSA:3.30.460.10 8 174 5.6E-26 T 28-03-2018 CO689_RS09030 d7ff61b27b13f30a7bae4cb83a026d35 175 SUPERFAMILY SSF81301 17 172 2.32E-32 T 28-03-2018 CO689_RS09030 d7ff61b27b13f30a7bae4cb83a026d35 175 Pfam PF04229 GrpB protein 16 170 1.2E-24 T 28-03-2018 IPR007344 GrpB/Dephospho-CoA kinase CO689_RS08085 0eee527eb736d77045deef4c5153cc21 395 TIGRFAM TIGR01825 gly_Cac_T_rel: putative pyridoxal phosphate-dependent acyltransferase 9 395 4.0E-200 T 28-03-2018 IPR010962 Putative 8-amino-7-oxononanoate synthase, Archaea/Firmicutes type CO689_RS08085 0eee527eb736d77045deef4c5153cc21 395 Gene3D G3DSA:3.40.640.10 49 289 2.5E-51 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CO689_RS08085 0eee527eb736d77045deef4c5153cc21 395 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 240 249 - T 28-03-2018 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0008152|GO:0016740 CO689_RS08085 0eee527eb736d77045deef4c5153cc21 395 Gene3D G3DSA:3.90.1150.10 290 393 1.8E-29 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CO689_RS08085 0eee527eb736d77045deef4c5153cc21 395 Pfam PF00155 Aminotransferase class I and II 42 384 6.4E-69 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CO689_RS08085 0eee527eb736d77045deef4c5153cc21 395 SUPERFAMILY SSF53383 7 393 2.82E-113 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CO689_RS03775 5ea0d913198a23596a295a1f9bb7d4f0 406 TIGRFAM TIGR00710 efflux_Bcr_CflA: drug resistance transporter, Bcr/CflA subfamily 15 392 1.5E-84 T 28-03-2018 IPR004812 Drug resistance transporter Bcr/CmlA subfamily GO:0005215|GO:0006810|GO:0016021 CO689_RS03775 5ea0d913198a23596a295a1f9bb7d4f0 406 Gene3D G3DSA:1.20.1250.20 6 203 4.9E-29 T 28-03-2018 CO689_RS03775 5ea0d913198a23596a295a1f9bb7d4f0 406 Pfam PF07690 Major Facilitator Superfamily 22 361 1.3E-38 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CO689_RS03775 5ea0d913198a23596a295a1f9bb7d4f0 406 Gene3D G3DSA:1.20.1250.20 204 396 1.8E-14 T 28-03-2018 CO689_RS03775 5ea0d913198a23596a295a1f9bb7d4f0 406 SUPERFAMILY SSF103473 9 396 3.66E-58 T 28-03-2018 IPR020846 Major facilitator superfamily domain CO689_RS00700 309319cd9c1d0919cf564bb14c873298 538 Gene3D G3DSA:1.50.10.20 266 476 3.2E-9 T 28-03-2018 CO689_RS00700 309319cd9c1d0919cf564bb14c873298 538 SUPERFAMILY SSF48208 199 405 4.54E-8 T 28-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 CO689_RS00700 309319cd9c1d0919cf564bb14c873298 538 Gene3D G3DSA:1.50.10.20 185 265 0.03 T 28-03-2018 CO689_RS04015 95780bc86d2b4a396c2ffb0d5b77e9f7 300 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 3 180 1.0E-38 T 28-03-2018 IPR003495 CobW/HypB/UreG, nucleotide-binding domain CO689_RS04015 95780bc86d2b4a396c2ffb0d5b77e9f7 300 Pfam PF07683 Cobalamin synthesis protein cobW C-terminal domain 223 295 6.5E-12 T 28-03-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal CO689_RS04015 95780bc86d2b4a396c2ffb0d5b77e9f7 300 Gene3D G3DSA:3.30.1220.10 203 299 3.8E-11 T 28-03-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal CO689_RS04015 95780bc86d2b4a396c2ffb0d5b77e9f7 300 SUPERFAMILY SSF52540 3 280 2.28E-22 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CO689_RS04015 95780bc86d2b4a396c2ffb0d5b77e9f7 300 Gene3D G3DSA:3.40.50.300 1 199 4.7E-30 T 28-03-2018 CO689_RS03240 f12a03cfa7afa75939fe22e5fac3339e 138 SUPERFAMILY SSF46785 3 136 2.19E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS03240 f12a03cfa7afa75939fe22e5fac3339e 138 Gene3D G3DSA:1.10.10.10 1 138 9.9E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS03240 f12a03cfa7afa75939fe22e5fac3339e 138 SMART SM00347 23 124 2.9E-11 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CO689_RS03240 f12a03cfa7afa75939fe22e5fac3339e 138 Pfam PF13463 Winged helix DNA-binding domain 32 95 2.3E-7 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CO689_RS07915 22efe83e7a745dffdd0d84b8ba6fbe51 295 PIRSF PIRSF029271 2 295 7.1E-150 T 28-03-2018 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 CO689_RS07915 22efe83e7a745dffdd0d84b8ba6fbe51 295 SUPERFAMILY SSF51366 19 268 9.42E-70 T 28-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 CO689_RS07915 22efe83e7a745dffdd0d84b8ba6fbe51 295 ProSitePatterns PS01235 PdxS/SNZ family signature. 206 224 - T 28-03-2018 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 CO689_RS07915 22efe83e7a745dffdd0d84b8ba6fbe51 295 TIGRFAM TIGR00343 TIGR00343: pyridoxal 5'-phosphate synthase, synthase subunit Pdx1 10 295 1.1E-151 T 28-03-2018 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 CO689_RS07915 22efe83e7a745dffdd0d84b8ba6fbe51 295 Gene3D G3DSA:3.20.20.70 19 272 4.2E-71 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CO689_RS07915 22efe83e7a745dffdd0d84b8ba6fbe51 295 Hamap MF_01824 Pyridoxal 5'-phosphate synthase subunit PdxS [pdxS]. 5 295 52.213 T 28-03-2018 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 CO689_RS07915 22efe83e7a745dffdd0d84b8ba6fbe51 295 Pfam PF01680 SOR/SNZ family 9 213 1.6E-105 T 28-03-2018 IPR033755 PdxS/SNZ N-terminal domain KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 CO689_RS13515 8cc984440a8a641887dbe7f972cbff2b 172 Pfam PF00156 Phosphoribosyl transferase domain 44 164 8.6E-14 T 28-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 CO689_RS13515 8cc984440a8a641887dbe7f972cbff2b 172 SUPERFAMILY SSF53271 3 164 3.27E-48 T 28-03-2018 IPR029057 Phosphoribosyltransferase-like CO689_RS13515 8cc984440a8a641887dbe7f972cbff2b 172 TIGRFAM TIGR01090 apt: adenine phosphoribosyltransferase 3 170 1.5E-68 T 28-03-2018 IPR005764 Adenine phosphoribosyl transferase GO:0003999|GO:0005737|GO:0006168 KEGG: 00230+2.4.2.7|MetaCyc: PWY-6605|MetaCyc: PWY-6610|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-6798695|Reactome: R-HSA-74217 CO689_RS13515 8cc984440a8a641887dbe7f972cbff2b 172 Hamap MF_00004 Adenine phosphoribosyltransferase [apt]. 3 170 37.834 T 28-03-2018 IPR005764 Adenine phosphoribosyl transferase GO:0003999|GO:0005737|GO:0006168 KEGG: 00230+2.4.2.7|MetaCyc: PWY-6605|MetaCyc: PWY-6610|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-6798695|Reactome: R-HSA-74217 CO689_RS13515 8cc984440a8a641887dbe7f972cbff2b 172 Gene3D G3DSA:3.40.50.2020 1 172 1.5E-36 T 28-03-2018 CO689_RS02145 a98110a059789598dca5900791e40de7 213 Pfam PF06971 Putative DNA-binding protein N-terminus 7 55 1.7E-19 T 28-03-2018 IPR009718 Rex DNA-binding, C-terminal domain GO:0005737|GO:0045892|GO:0051775 CO689_RS02145 a98110a059789598dca5900791e40de7 213 Gene3D G3DSA:3.40.50.720 79 211 8.5E-17 T 28-03-2018 CO689_RS02145 a98110a059789598dca5900791e40de7 213 SUPERFAMILY SSF46785 9 78 2.81E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS02145 a98110a059789598dca5900791e40de7 213 Gene3D G3DSA:1.10.10.10 6 75 1.8E-26 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS02145 a98110a059789598dca5900791e40de7 213 SMART SM00881 82 182 1.4E-13 T 28-03-2018 IPR003781 CoA-binding GO:0048037 CO689_RS02145 a98110a059789598dca5900791e40de7 213 Hamap MF_01131 Redox-sensing transcriptional repressor Rex [rex]. 3 211 36.784 T 28-03-2018 IPR022876 Redox-sensing transcriptional repressor Rex GO:0005737|GO:0045892|GO:0051775 CO689_RS02145 a98110a059789598dca5900791e40de7 213 SUPERFAMILY SSF51735 85 208 5.42E-27 T 28-03-2018 IPR016040 NAD(P)-binding domain CO689_RS02145 a98110a059789598dca5900791e40de7 213 Pfam PF02629 CoA binding domain 87 180 3.5E-21 T 28-03-2018 IPR003781 CoA-binding GO:0048037 CO689_RS05445 6c89efd85db2ccbbd031e20e43419d65 344 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 155 333 4.7E-10 T 28-03-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 CO689_RS05445 6c89efd85db2ccbbd031e20e43419d65 344 SUPERFAMILY SSF48150 142 343 4.01E-31 T 28-03-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 CO689_RS05445 6c89efd85db2ccbbd031e20e43419d65 344 Gene3D G3DSA:1.10.340.30 146 293 1.2E-19 T 28-03-2018 CO689_RS05445 6c89efd85db2ccbbd031e20e43419d65 344 Gene3D G3DSA:3.30.310.20 8 145 1.4E-24 T 28-03-2018 IPR010316 DNA-3-methyladenine glycosylase AlkA, N-terminal CO689_RS05445 6c89efd85db2ccbbd031e20e43419d65 344 SMART SM00478 159 344 1.1E-5 T 28-03-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 CO689_RS05445 6c89efd85db2ccbbd031e20e43419d65 344 Pfam PF06029 AlkA N-terminal domain 36 146 5.9E-25 T 28-03-2018 IPR010316 DNA-3-methyladenine glycosylase AlkA, N-terminal CO689_RS05445 6c89efd85db2ccbbd031e20e43419d65 344 Gene3D G3DSA:1.10.1670.10 295 344 1.2E-10 T 28-03-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 CO689_RS05445 6c89efd85db2ccbbd031e20e43419d65 344 SMART SM01009 35 149 5.4E-24 T 28-03-2018 IPR010316 DNA-3-methyladenine glycosylase AlkA, N-terminal CO689_RS05445 6c89efd85db2ccbbd031e20e43419d65 344 SUPERFAMILY SSF55945 35 132 2.67E-20 T 28-03-2018 CO689_RS03420 500aae699f534ea294c0821616a0401e 279 Hamap MF_01384 Urease accessory protein UreD [ureD]. 7 265 22.799 T 28-03-2018 IPR002669 Urease accessory protein UreD GO:0006807|GO:0016151 CO689_RS03420 500aae699f534ea294c0821616a0401e 279 Pfam PF01774 UreD urease accessory protein 50 251 4.1E-45 T 28-03-2018 IPR002669 Urease accessory protein UreD GO:0006807|GO:0016151 CO689_RS00620 4c7f4b7a0b8836daafc30de8ef3e15df 257 SUPERFAMILY SSF56601 4 138 1.0E-14 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CO689_RS00620 4c7f4b7a0b8836daafc30de8ef3e15df 257 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 3 108 1.2E-11 T 28-03-2018 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 CO689_RS00620 4c7f4b7a0b8836daafc30de8ef3e15df 257 Gene3D G3DSA:3.40.710.10 148 257 2.5E-11 T 28-03-2018 CO689_RS00620 4c7f4b7a0b8836daafc30de8ef3e15df 257 Pfam PF13354 Beta-lactamase enzyme family 171 253 4.9E-6 T 28-03-2018 CO689_RS00620 4c7f4b7a0b8836daafc30de8ef3e15df 257 SUPERFAMILY SSF56601 153 253 3.87E-15 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CO689_RS00620 4c7f4b7a0b8836daafc30de8ef3e15df 257 Gene3D G3DSA:3.40.710.10 1 147 5.4E-10 T 28-03-2018 CO689_RS04810 08716dd9da039b0b3df8f94f3e288d5e 541 Gene3D G3DSA:1.10.10.60 465 511 9.1E-6 T 28-03-2018 CO689_RS04810 08716dd9da039b0b3df8f94f3e288d5e 541 Pfam PF13556 PucR C-terminal helix-turn-helix domain 476 532 7.3E-19 T 28-03-2018 IPR025736 PucR C-terminal helix-turn-helix domain CO689_RS04810 08716dd9da039b0b3df8f94f3e288d5e 541 Pfam PF07905 Purine catabolism regulatory protein-like family 7 125 4.9E-27 T 28-03-2018 IPR012914 Purine catabolism PurC-like domain CO689_RS08100 ff3e02429829c0ebf54d0429bb1e2e3b 339 Pfam PF02275 Linear amide C-N hydrolases, choloylglycine hydrolase family 2 314 2.8E-72 T 28-03-2018 IPR029132 Choloylglycine hydrolase/NAAA C-terminal CO689_RS08100 ff3e02429829c0ebf54d0429bb1e2e3b 339 Gene3D G3DSA:3.60.60.10 2 332 5.3E-71 T 28-03-2018 CO689_RS08100 ff3e02429829c0ebf54d0429bb1e2e3b 339 SUPERFAMILY SSF56235 2 322 7.64E-85 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CO689_RS00315 02e82167b289376cf098d7dcebdbb438 448 Gene3D G3DSA:3.30.390.30 331 448 5.8E-31 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CO689_RS00315 02e82167b289376cf098d7dcebdbb438 448 Gene3D G3DSA:3.50.50.60 2 158 1.7E-17 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CO689_RS00315 02e82167b289376cf098d7dcebdbb438 448 SUPERFAMILY SSF55424 336 447 6.7E-32 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CO689_RS00315 02e82167b289376cf098d7dcebdbb438 448 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 400 415 2.5E-51 T 28-03-2018 CO689_RS00315 02e82167b289376cf098d7dcebdbb438 448 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 133 142 2.5E-51 T 28-03-2018 CO689_RS00315 02e82167b289376cf098d7dcebdbb438 448 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 255 269 2.5E-51 T 28-03-2018 CO689_RS00315 02e82167b289376cf098d7dcebdbb438 448 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 167 192 2.5E-51 T 28-03-2018 CO689_RS00315 02e82167b289376cf098d7dcebdbb438 448 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 297 304 2.5E-51 T 28-03-2018 CO689_RS00315 02e82167b289376cf098d7dcebdbb438 448 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 6 28 2.5E-51 T 28-03-2018 CO689_RS00315 02e82167b289376cf098d7dcebdbb438 448 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 38 53 2.5E-51 T 28-03-2018 CO689_RS00315 02e82167b289376cf098d7dcebdbb438 448 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 422 442 2.5E-51 T 28-03-2018 CO689_RS00315 02e82167b289376cf098d7dcebdbb438 448 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 335 356 2.5E-51 T 28-03-2018 CO689_RS00315 02e82167b289376cf098d7dcebdbb438 448 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 339 445 2.6E-23 T 28-03-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 CO689_RS00315 02e82167b289376cf098d7dcebdbb438 448 Gene3D G3DSA:3.50.50.60 167 330 1.2E-25 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CO689_RS00315 02e82167b289376cf098d7dcebdbb438 448 SUPERFAMILY SSF51905 1 327 4.29E-50 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CO689_RS00315 02e82167b289376cf098d7dcebdbb438 448 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 5 317 8.5E-51 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CO689_RS00315 02e82167b289376cf098d7dcebdbb438 448 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 254 270 1.2E-17 T 28-03-2018 CO689_RS00315 02e82167b289376cf098d7dcebdbb438 448 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 282 304 1.2E-17 T 28-03-2018 CO689_RS00315 02e82167b289376cf098d7dcebdbb438 448 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 7 26 1.2E-17 T 28-03-2018 CO689_RS00315 02e82167b289376cf098d7dcebdbb438 448 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 130 148 1.2E-17 T 28-03-2018 CO689_RS00315 02e82167b289376cf098d7dcebdbb438 448 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 167 185 1.2E-17 T 28-03-2018 CO689_RS00315 02e82167b289376cf098d7dcebdbb438 448 PIRSF PIRSF000350 2 446 2.4E-67 T 28-03-2018 CO689_RS11625 8fba20356291f2f6891cf540a7a37019 256 SUPERFAMILY SSF53098 66 254 1.67E-66 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CO689_RS11625 8fba20356291f2f6891cf540a7a37019 256 Hamap MF_00052_B Ribonuclease HII [rnhB]. 73 250 34.127 T 28-03-2018 IPR022898 Ribonuclease HII GO:0004523 CO689_RS11625 8fba20356291f2f6891cf540a7a37019 256 Pfam PF01351 Ribonuclease HII 75 248 3.9E-36 T 28-03-2018 IPR024567 Ribonuclease HII/HIII domain CO689_RS11625 8fba20356291f2f6891cf540a7a37019 256 Gene3D G3DSA:3.30.420.10 48 256 6.3E-66 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CO689_RS02385 2f97f61d8d39bca7c6e63282bc42c455 264 Gene3D G3DSA:3.40.1190.20 1 264 1.0E-52 T 28-03-2018 IPR029056 Ribokinase-like CO689_RS02385 2f97f61d8d39bca7c6e63282bc42c455 264 PIRSF PIRSF000513 1 263 2.4E-88 T 28-03-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CO689_RS02385 2f97f61d8d39bca7c6e63282bc42c455 264 TIGRFAM TIGR00694 thiM: hydroxyethylthiazole kinase 5 253 1.0E-79 T 28-03-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CO689_RS02385 2f97f61d8d39bca7c6e63282bc42c455 264 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 26 47 1.2E-32 T 28-03-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CO689_RS02385 2f97f61d8d39bca7c6e63282bc42c455 264 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 83 100 1.2E-32 T 28-03-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CO689_RS02385 2f97f61d8d39bca7c6e63282bc42c455 264 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 13 20 1.2E-32 T 28-03-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CO689_RS02385 2f97f61d8d39bca7c6e63282bc42c455 264 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 157 174 1.2E-32 T 28-03-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CO689_RS02385 2f97f61d8d39bca7c6e63282bc42c455 264 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 114 128 1.2E-32 T 28-03-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CO689_RS02385 2f97f61d8d39bca7c6e63282bc42c455 264 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 57 65 1.2E-32 T 28-03-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CO689_RS02385 2f97f61d8d39bca7c6e63282bc42c455 264 Hamap MF_00228 Hydroxyethylthiazole kinase [thiM]. 7 256 30.03 T 28-03-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CO689_RS02385 2f97f61d8d39bca7c6e63282bc42c455 264 Pfam PF02110 Hydroxyethylthiazole kinase family 5 252 8.8E-79 T 28-03-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CO689_RS02385 2f97f61d8d39bca7c6e63282bc42c455 264 SUPERFAMILY SSF53613 4 259 7.95E-59 T 28-03-2018 IPR029056 Ribokinase-like CO689_RS08235 8a2d9d1c5bd04c0fb6c6ba4a56ef1cfa 276 Pfam PF08543 Phosphomethylpyrimidine kinase 13 259 1.1E-75 T 28-03-2018 IPR013749 Pyridoxamine kinase/Phosphomethylpyrimidine kinase Reactome: R-HSA-6798695|Reactome: R-HSA-964975 CO689_RS08235 8a2d9d1c5bd04c0fb6c6ba4a56ef1cfa 276 TIGRFAM TIGR00097 HMP-P_kinase: hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 6 260 2.9E-71 T 28-03-2018 IPR004399 Hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase GO:0008972|GO:0009228 KEGG: 00730+2.7.1.49|MetaCyc: PWY-6910|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CO689_RS08235 8a2d9d1c5bd04c0fb6c6ba4a56ef1cfa 276 SUPERFAMILY SSF53613 4 266 1.04E-64 T 28-03-2018 IPR029056 Ribokinase-like CO689_RS08235 8a2d9d1c5bd04c0fb6c6ba4a56ef1cfa 276 Gene3D G3DSA:3.40.1190.20 1 276 9.4E-51 T 28-03-2018 IPR029056 Ribokinase-like CO689_RS07175 7ae29324832d0d250ef5fa539ab0685f 146 Pfam PF02627 Carboxymuconolactone decarboxylase family 26 93 1.6E-14 T 28-03-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 CO689_RS07175 7ae29324832d0d250ef5fa539ab0685f 146 Gene3D G3DSA:1.20.1290.10 1 146 6.4E-32 T 28-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 CO689_RS07175 7ae29324832d0d250ef5fa539ab0685f 146 SUPERFAMILY SSF69118 3 145 6.67E-40 T 28-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 CO689_RS07175 7ae29324832d0d250ef5fa539ab0685f 146 TIGRFAM TIGR00778 ahpD_dom: alkylhydroperoxidase AhpD family core domain 29 76 6.9E-18 T 28-03-2018 IPR004675 Alkylhydroperoxidase AhpD core GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 CO689_RS11780 ebcd54f652940c7aa57154f46997bb5c 458 Gene3D G3DSA:1.10.287.130 221 294 1.2E-16 T 28-03-2018 CO689_RS11780 ebcd54f652940c7aa57154f46997bb5c 458 SMART SM00388 231 298 8.5E-14 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CO689_RS11780 ebcd54f652940c7aa57154f46997bb5c 458 SUPERFAMILY SSF55874 288 446 6.68E-36 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CO689_RS11780 ebcd54f652940c7aa57154f46997bb5c 458 Pfam PF00512 His Kinase A (phospho-acceptor) domain 232 296 1.2E-13 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CO689_RS11780 ebcd54f652940c7aa57154f46997bb5c 458 SMART SM00387 340 450 1.0E-27 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CO689_RS11780 ebcd54f652940c7aa57154f46997bb5c 458 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 342 446 1.9E-19 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CO689_RS11780 ebcd54f652940c7aa57154f46997bb5c 458 Gene3D G3DSA:3.30.565.10 302 458 1.0E-31 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CO689_RS11780 ebcd54f652940c7aa57154f46997bb5c 458 SUPERFAMILY SSF47384 214 298 1.9E-17 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CO689_RS11780 ebcd54f652940c7aa57154f46997bb5c 458 PRINTS PR00344 Bacterial sensor protein C-terminal signature 393 403 1.4E-8 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CO689_RS11780 ebcd54f652940c7aa57154f46997bb5c 458 PRINTS PR00344 Bacterial sensor protein C-terminal signature 375 389 1.4E-8 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CO689_RS11780 ebcd54f652940c7aa57154f46997bb5c 458 PRINTS PR00344 Bacterial sensor protein C-terminal signature 434 447 1.4E-8 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CO689_RS11780 ebcd54f652940c7aa57154f46997bb5c 458 PRINTS PR00344 Bacterial sensor protein C-terminal signature 410 428 1.4E-8 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CO689_RS12825 df312ed627b094f9a6a9903266006fa9 324 Pfam PF00710 Asparaginase, N-terminal 3 191 1.4E-59 T 28-03-2018 IPR027474 L-asparaginase, N-terminal Reactome: R-HSA-70614 CO689_RS12825 df312ed627b094f9a6a9903266006fa9 324 PRINTS PR00139 Asparaginase/glutaminase family signature 79 97 1.2E-16 T 28-03-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 CO689_RS12825 df312ed627b094f9a6a9903266006fa9 324 PRINTS PR00139 Asparaginase/glutaminase family signature 252 270 1.2E-16 T 28-03-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 CO689_RS12825 df312ed627b094f9a6a9903266006fa9 324 PRINTS PR00139 Asparaginase/glutaminase family signature 4 15 1.2E-16 T 28-03-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 CO689_RS12825 df312ed627b094f9a6a9903266006fa9 324 ProSitePatterns PS00144 Asparaginase / glutaminase active site signature 1. 6 14 - T 28-03-2018 IPR020827 Asparaginase/glutaminase, active site 1 GO:0006520 CO689_RS12825 df312ed627b094f9a6a9903266006fa9 324 Gene3D G3DSA:3.40.50.40 205 322 5.9E-25 T 28-03-2018 IPR027473 L-asparaginase, C-terminal domain Reactome: R-HSA-70614 CO689_RS12825 df312ed627b094f9a6a9903266006fa9 324 ProSitePatterns PS00917 Asparaginase / glutaminase active site signature 2. 80 90 - T 28-03-2018 IPR027475 Asparaginase/glutaminase, active site 2 Reactome: R-HSA-70614 CO689_RS12825 df312ed627b094f9a6a9903266006fa9 324 Gene3D G3DSA:3.40.50.1170 1 203 1.1E-56 T 28-03-2018 IPR027474 L-asparaginase, N-terminal Reactome: R-HSA-70614 CO689_RS12825 df312ed627b094f9a6a9903266006fa9 324 SUPERFAMILY SSF53774 2 321 7.33E-98 T 28-03-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 CO689_RS12825 df312ed627b094f9a6a9903266006fa9 324 SMART SM00870 3 317 1.5E-131 T 28-03-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 CO689_RS12825 df312ed627b094f9a6a9903266006fa9 324 PIRSF PIRSF001220 1 323 3.0E-90 T 28-03-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 CO689_RS12825 df312ed627b094f9a6a9903266006fa9 324 PIRSF PIRSF500176 1 324 1.3E-90 T 28-03-2018 CO689_RS06175 d66b26b2c8bceb2e7f1e4c6fb1484056 193 Pfam PF01420 Type I restriction modification DNA specificity domain 36 171 4.2E-6 T 28-03-2018 IPR000055 Restriction endonuclease, type I, HsdS GO:0003677|GO:0006304 CO689_RS06175 d66b26b2c8bceb2e7f1e4c6fb1484056 193 Gene3D G3DSA:3.90.220.20 2 180 4.5E-14 T 28-03-2018 CO689_RS06175 d66b26b2c8bceb2e7f1e4c6fb1484056 193 SUPERFAMILY SSF116734 14 180 4.91E-17 T 28-03-2018 CO689_RS07200 43928739ebc4d20dbfbf209e9dc80aca 189 Gene3D G3DSA:3.40.30.10 3 157 2.3E-30 T 28-03-2018 CO689_RS07200 43928739ebc4d20dbfbf209e9dc80aca 189 Pfam PF10417 C-terminal domain of 1-Cys peroxiredoxin 158 179 2.6E-4 T 28-03-2018 IPR019479 Peroxiredoxin, C-terminal GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 CO689_RS07200 43928739ebc4d20dbfbf209e9dc80aca 189 Pfam PF00578 AhpC/TSA family 11 135 1.0E-31 T 28-03-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 CO689_RS07200 43928739ebc4d20dbfbf209e9dc80aca 189 Gene3D G3DSA:3.30.1020.10 158 184 1.5E-6 T 28-03-2018 CO689_RS07200 43928739ebc4d20dbfbf209e9dc80aca 189 PIRSF PIRSF000239 1 189 8.4E-49 T 28-03-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 CO689_RS07200 43928739ebc4d20dbfbf209e9dc80aca 189 TIGRFAM TIGR03137 AhpC: peroxiredoxin 1 189 8.0E-97 T 28-03-2018 IPR017559 Alkyl hydroperoxide reductase subunit C GO:0006979|GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 CO689_RS07200 43928739ebc4d20dbfbf209e9dc80aca 189 SUPERFAMILY SSF52833 3 188 5.61E-51 T 28-03-2018 IPR012336 Thioredoxin-like fold CO689_RS05885 66ffc402b0f33dd145f55210fdefff33 1043 Gene3D G3DSA:2.60.40.1290 515 690 1.3E-37 T 28-03-2018 CO689_RS05885 66ffc402b0f33dd145f55210fdefff33 1043 Pfam PF04650 YSIRK type signal peptide 8 32 3.3E-11 T 28-03-2018 IPR005877 YSIRK Gram-positive signal peptide GO:0016020 CO689_RS05885 66ffc402b0f33dd145f55210fdefff33 1043 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 1005 1040 7.2E-7 T 28-03-2018 CO689_RS05885 66ffc402b0f33dd145f55210fdefff33 1043 Pfam PF00746 LPXTG cell wall anchor motif 1003 1041 2.5E-9 T 28-03-2018 IPR019948 Gram-positive LPXTG cell wall anchor CO689_RS05885 66ffc402b0f33dd145f55210fdefff33 1043 SUPERFAMILY SSF49401 365 507 1.08E-28 T 28-03-2018 IPR008966 Adhesion domain CO689_RS05885 66ffc402b0f33dd145f55210fdefff33 1043 SUPERFAMILY SSF49401 511 701 3.07E-29 T 28-03-2018 IPR008966 Adhesion domain CO689_RS05885 66ffc402b0f33dd145f55210fdefff33 1043 Pfam PF10425 C-terminus of bacterial fibrinogen-binding adhesin 513 683 3.3E-42 T 28-03-2018 IPR011266 Fibrinogen-binding domain 2 GO:0005618|GO:0007155 CO689_RS05885 66ffc402b0f33dd145f55210fdefff33 1043 TIGRFAM TIGR01168 YSIRK_signal: gram-positive signal peptide, YSIRK family 6 43 9.6E-13 T 28-03-2018 IPR005877 YSIRK Gram-positive signal peptide GO:0016020 CO689_RS05885 66ffc402b0f33dd145f55210fdefff33 1043 Gene3D G3DSA:2.60.40.1280 365 514 2.6E-33 T 28-03-2018 IPR011252 Fibrogen-binding domain 1 GO:0005618|GO:0007155 CO689_RS04820 f1510213aa9302b6c573f43b88bd9607 390 Gene3D G3DSA:1.10.260.40 1 149 2.4E-7 T 28-03-2018 CO689_RS04820 f1510213aa9302b6c573f43b88bd9607 390 SUPERFAMILY SSF47413 1 63 2.5E-6 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CO689_RS04820 f1510213aa9302b6c573f43b88bd9607 390 Pfam PF06114 IrrE N-terminal-like domain 178 286 5.1E-15 T 28-03-2018 IPR010359 IrrE N-terminal-like domain CO689_RS13265 68d35c93726f0d1b41321a4556ead46c 328 Hamap MF_01562 UPF0365 protein . 1 320 46.948 T 28-03-2018 IPR022853 Uncharacterised protein family YdfA-immunity CO689_RS13265 68d35c93726f0d1b41321a4556ead46c 328 Gene3D G3DSA:1.10.287.40 187 287 6.5E-4 T 28-03-2018 CO689_RS13265 68d35c93726f0d1b41321a4556ead46c 328 Pfam PF12127 SigmaW regulon antibacterial 6 317 3.4E-162 T 28-03-2018 IPR022853 Uncharacterised protein family YdfA-immunity CO689_RS09140 1b4728570b916efe69b713f4b974439c 310 SUPERFAMILY SSF53795 131 297 6.41E-40 T 28-03-2018 CO689_RS09140 1b4728570b916efe69b713f4b974439c 310 Gene3D G3DSA:3.40.1390.20 1 130 1.3E-43 T 28-03-2018 IPR028979 HPr(Ser) kinase/phosphorylase, N-terminal domain-like CO689_RS09140 1b4728570b916efe69b713f4b974439c 310 TIGRFAM TIGR00679 hpr-ser: HPr(Ser) kinase/phosphatase 5 300 1.4E-117 T 28-03-2018 IPR003755 HPr(Ser) kinase/phosphorylase GO:0000155|GO:0000160|GO:0005524|GO:0006109 CO689_RS09140 1b4728570b916efe69b713f4b974439c 310 Pfam PF02603 HPr Serine kinase N terminus 4 125 5.2E-40 T 28-03-2018 IPR011126 HPr(Ser) kinase/phosphorylase, N-terminal GO:0000155|GO:0000160|GO:0004672|GO:0005524|GO:0006109 CO689_RS09140 1b4728570b916efe69b713f4b974439c 310 Gene3D G3DSA:3.40.50.300 131 305 1.8E-43 T 28-03-2018 CO689_RS09140 1b4728570b916efe69b713f4b974439c 310 Pfam PF07475 HPr Serine kinase C-terminal domain 128 296 8.9E-75 T 28-03-2018 IPR011104 HPr kinase/phosphorylase, C-terminal GO:0000155|GO:0000160|GO:0004672|GO:0005524|GO:0006109 CO689_RS09140 1b4728570b916efe69b713f4b974439c 310 Hamap MF_01249 HPr kinase/phosphorylase [hprK]. 1 304 41.541 T 28-03-2018 IPR003755 HPr(Ser) kinase/phosphorylase GO:0000155|GO:0000160|GO:0005524|GO:0006109 CO689_RS09140 1b4728570b916efe69b713f4b974439c 310 SUPERFAMILY SSF75138 4 128 7.98E-40 T 28-03-2018 IPR028979 HPr(Ser) kinase/phosphorylase, N-terminal domain-like CO689_RS07810 132e021c1fd40f300f902cb263a9c32d 495 TIGRFAM TIGR00499 lysS_bact: lysine--tRNA ligase 5 494 2.7E-221 T 28-03-2018 IPR002313 Lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CO689_RS07810 132e021c1fd40f300f902cb263a9c32d 495 PRINTS PR00982 Lysyl-tRNA synthetase signature 236 249 3.2E-40 T 28-03-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CO689_RS07810 132e021c1fd40f300f902cb263a9c32d 495 PRINTS PR00982 Lysyl-tRNA synthetase signature 377 393 3.2E-40 T 28-03-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CO689_RS07810 132e021c1fd40f300f902cb263a9c32d 495 PRINTS PR00982 Lysyl-tRNA synthetase signature 207 223 3.2E-40 T 28-03-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CO689_RS07810 132e021c1fd40f300f902cb263a9c32d 495 PRINTS PR00982 Lysyl-tRNA synthetase signature 191 201 3.2E-40 T 28-03-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CO689_RS07810 132e021c1fd40f300f902cb263a9c32d 495 PRINTS PR00982 Lysyl-tRNA synthetase signature 254 271 3.2E-40 T 28-03-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CO689_RS07810 132e021c1fd40f300f902cb263a9c32d 495 Gene3D G3DSA:2.40.50.140 5 147 4.5E-41 T 28-03-2018 CO689_RS07810 132e021c1fd40f300f902cb263a9c32d 495 Gene3D G3DSA:3.30.930.10 148 492 2.0E-106 T 28-03-2018 CO689_RS07810 132e021c1fd40f300f902cb263a9c32d 495 Pfam PF01336 OB-fold nucleic acid binding domain 61 135 1.2E-12 T 28-03-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 CO689_RS07810 132e021c1fd40f300f902cb263a9c32d 495 SUPERFAMILY SSF55681 154 493 1.81E-123 T 28-03-2018 CO689_RS07810 132e021c1fd40f300f902cb263a9c32d 495 Hamap MF_00252 Lysine--tRNA ligase [lysS]. 11 495 46.147 T 28-03-2018 IPR002313 Lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CO689_RS07810 132e021c1fd40f300f902cb263a9c32d 495 SUPERFAMILY SSF50249 4 147 4.0E-43 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CO689_RS07810 132e021c1fd40f300f902cb263a9c32d 495 PIRSF PIRSF039101 1 495 3.2E-198 T 28-03-2018 IPR034762 Bacterial/eukaryotic lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CO689_RS07810 132e021c1fd40f300f902cb263a9c32d 495 Pfam PF00152 tRNA synthetases class II (D, K and N) 156 492 6.3E-83 T 28-03-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 CO689_RS08560 91acd4fcbee34826a812c4a0031b8a79 226 SUPERFAMILY SSF46894 125 221 6.24E-25 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CO689_RS08560 91acd4fcbee34826a812c4a0031b8a79 226 SUPERFAMILY SSF52172 1 122 5.98E-34 T 28-03-2018 IPR011006 CheY-like superfamily CO689_RS08560 91acd4fcbee34826a812c4a0031b8a79 226 SMART SM00862 147 222 2.5E-19 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CO689_RS08560 91acd4fcbee34826a812c4a0031b8a79 226 Pfam PF00486 Transcriptional regulatory protein, C terminal 148 221 1.1E-22 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CO689_RS08560 91acd4fcbee34826a812c4a0031b8a79 226 Gene3D G3DSA:3.40.50.2300 1 122 1.3E-29 T 28-03-2018 CO689_RS08560 91acd4fcbee34826a812c4a0031b8a79 226 Gene3D G3DSA:1.10.10.10 123 225 6.4E-25 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS08560 91acd4fcbee34826a812c4a0031b8a79 226 Pfam PF00072 Response regulator receiver domain 3 111 1.9E-23 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CO689_RS08560 91acd4fcbee34826a812c4a0031b8a79 226 SMART SM00448 1 111 2.9E-31 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CO689_RS13585 4450fc1fcf6dad745c28c22f58f33f2c 279 PIRSF PIRSF038471 1 279 2.8E-54 T 28-03-2018 IPR007221 Rod shape-determining protein MreC GO:0008360 CO689_RS13585 4450fc1fcf6dad745c28c22f58f33f2c 279 Gene3D G3DSA:1.10.10.60 64 100 2.9E-4 T 28-03-2018 CO689_RS13585 4450fc1fcf6dad745c28c22f58f33f2c 279 Pfam PF04085 rod shape-determining protein MreC 114 265 4.6E-41 T 28-03-2018 IPR007221 Rod shape-determining protein MreC GO:0008360 CO689_RS13585 4450fc1fcf6dad745c28c22f58f33f2c 279 TIGRFAM TIGR00219 mreC: rod shape-determining protein MreC 67 270 8.3E-40 T 28-03-2018 IPR007221 Rod shape-determining protein MreC GO:0008360 CO689_RS12405 3802217e82d811057c69a4528881406a 603 Gene3D G3DSA:1.10.1370.10 78 581 3.4E-31 T 28-03-2018 CO689_RS12405 3802217e82d811057c69a4528881406a 603 SUPERFAMILY SSF55486 55 601 1.06E-99 T 28-03-2018 CO689_RS12405 3802217e82d811057c69a4528881406a 603 Pfam PF08439 Oligopeptidase F 115 180 4.3E-16 T 28-03-2018 IPR013647 Oligopeptidase F, N-terminal domain CO689_RS12405 3802217e82d811057c69a4528881406a 603 Pfam PF01432 Peptidase family M3 203 581 1.2E-34 T 28-03-2018 IPR001567 Peptidase M3A/M3B catalytic domain GO:0004222|GO:0006508 CO689_RS12405 3802217e82d811057c69a4528881406a 603 TIGRFAM TIGR00181 pepF: oligoendopeptidase F 8 595 8.4E-200 T 28-03-2018 IPR004438 Peptidase M3B, oligoendopeptidase F GO:0004222|GO:0006508 CO689_RS04555 086970cea4bb8819b6703d22a651c955 146 Gene3D G3DSA:2.20.25.10 109 144 0.0013 T 28-03-2018 CO689_RS04555 086970cea4bb8819b6703d22a651c955 146 Pfam PF04397 LytTr DNA-binding domain 49 144 1.5E-20 T 28-03-2018 IPR007492 LytTR DNA-binding domain GO:0003677 CO689_RS04555 086970cea4bb8819b6703d22a651c955 146 Gene3D G3DSA:2.40.50.40 39 108 1.5E-13 T 28-03-2018 CO689_RS04555 086970cea4bb8819b6703d22a651c955 146 SMART SM00850 49 145 3.5E-25 T 28-03-2018 IPR007492 LytTR DNA-binding domain GO:0003677 CO689_RS09425 73aa4c6bca9332642ffc5c126649dfde 438 Pfam PF14690 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 43 92 1.4E-6 T 28-03-2018 IPR029261 Transposase IS204/IS1001/IS1096/IS1165, zinc-finger CO689_RS09425 73aa4c6bca9332642ffc5c126649dfde 438 Pfam PF01610 Transposase 164 417 4.8E-62 T 28-03-2018 IPR002560 Transposase IS204/IS1001/IS1096/IS1165, DDE domain CO689_RS09425 73aa4c6bca9332642ffc5c126649dfde 438 Gene3D G3DSA:1.10.10.10 103 153 0.0016 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS11280 73aa4c6bca9332642ffc5c126649dfde 438 Pfam PF14690 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 43 92 1.4E-6 T 28-03-2018 IPR029261 Transposase IS204/IS1001/IS1096/IS1165, zinc-finger CO689_RS11280 73aa4c6bca9332642ffc5c126649dfde 438 Pfam PF01610 Transposase 164 417 4.8E-62 T 28-03-2018 IPR002560 Transposase IS204/IS1001/IS1096/IS1165, DDE domain CO689_RS11280 73aa4c6bca9332642ffc5c126649dfde 438 Gene3D G3DSA:1.10.10.10 103 153 0.0016 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS04610 73aa4c6bca9332642ffc5c126649dfde 438 Pfam PF14690 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 43 92 1.4E-6 T 28-03-2018 IPR029261 Transposase IS204/IS1001/IS1096/IS1165, zinc-finger CO689_RS04610 73aa4c6bca9332642ffc5c126649dfde 438 Pfam PF01610 Transposase 164 417 4.8E-62 T 28-03-2018 IPR002560 Transposase IS204/IS1001/IS1096/IS1165, DDE domain CO689_RS04610 73aa4c6bca9332642ffc5c126649dfde 438 Gene3D G3DSA:1.10.10.10 103 153 0.0016 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS11140 7b89c8a37b690dc9b08c072908ff2fcc 132 Pfam PF06803 Protein of unknown function (DUF1232) 36 72 1.9E-13 T 28-03-2018 IPR010652 Protein of unknown function DUF1232 CO689_RS03825 20a467bd98d3c63b78889c1d7b8b4e76 533 TIGRFAM TIGR00795 lctP: transporter, lactate permease (LctP) family 13 529 2.4E-146 T 28-03-2018 IPR003804 L-lactate permease GO:0005887|GO:0015129|GO:0015727 CO689_RS03825 20a467bd98d3c63b78889c1d7b8b4e76 533 Pfam PF02652 L-lactate permease 15 528 2.6E-149 T 28-03-2018 IPR003804 L-lactate permease GO:0005887|GO:0015129|GO:0015727 CO689_RS03715 58c176242c2839950fecb1e7fb28269e 175 Pfam PF13353 4Fe-4S single cluster domain 22 161 5.2E-45 T 28-03-2018 CO689_RS03715 58c176242c2839950fecb1e7fb28269e 175 TIGRFAM TIGR02491 NrdG: anaerobic ribonucleoside-triphosphate reductase activating protein 14 163 3.1E-47 T 28-03-2018 IPR012837 Ribonucleoside-triphosphate reductase activating, anaerobic GO:0005737|GO:0043365|GO:0051539|GO:0055114 CO689_RS03715 58c176242c2839950fecb1e7fb28269e 175 SUPERFAMILY SSF102114 34 132 1.04E-9 T 28-03-2018 CO689_RS03715 58c176242c2839950fecb1e7fb28269e 175 PIRSF PIRSF000368 3 175 2.1E-59 T 28-03-2018 IPR012837 Ribonucleoside-triphosphate reductase activating, anaerobic GO:0005737|GO:0043365|GO:0051539|GO:0055114 CO689_RS03715 58c176242c2839950fecb1e7fb28269e 175 Gene3D G3DSA:3.80.30.20 24 170 4.8E-9 T 28-03-2018 IPR023404 Radical SAM, alpha/beta horseshoe CO689_RS03100 b6a505521be8f52c111b2c24f0b959c9 122 SUPERFAMILY SSF50193 1 122 3.92E-50 T 28-03-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 CO689_RS03100 b6a505521be8f52c111b2c24f0b959c9 122 Pfam PF00238 Ribosomal protein L14p/L23e 1 122 9.6E-54 T 28-03-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 CO689_RS03100 b6a505521be8f52c111b2c24f0b959c9 122 Hamap MF_01367 50S ribosomal protein L14 [rplN]. 1 122 26.961 T 28-03-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 CO689_RS03100 b6a505521be8f52c111b2c24f0b959c9 122 SMART SM01374 1 122 3.8E-84 T 28-03-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 CO689_RS03100 b6a505521be8f52c111b2c24f0b959c9 122 TIGRFAM TIGR01067 rplN_bact: ribosomal protein uL14 1 122 6.4E-58 T 28-03-2018 IPR005745 Ribosomal protein L14P, bacterial-type GO:0003735|GO:0006412|GO:0015934 CO689_RS03100 b6a505521be8f52c111b2c24f0b959c9 122 ProSitePatterns PS00049 Ribosomal protein L14 signature. 60 86 - T 28-03-2018 IPR019972 Ribosomal protein L14P, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CO689_RS03100 b6a505521be8f52c111b2c24f0b959c9 122 Gene3D G3DSA:2.40.150.20 1 122 6.2E-52 T 28-03-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 CO689_RS05265 c7b9234e8eafe2549ea9fc821a7ffde8 382 Pfam PF06772 Bacterial low temperature requirement A protein (LtrA) 14 343 3.5E-46 T 28-03-2018 IPR010640 Low temperature requirement A CO689_RS11185 d94c09e1d0d6cb15c9d964d6ff7c5f84 226 Gene3D G3DSA:3.40.50.1000 90 226 3.0E-27 T 28-03-2018 IPR023214 HAD-like domain CO689_RS11185 d94c09e1d0d6cb15c9d964d6ff7c5f84 226 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 113 193 3.7E-12 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CO689_RS11185 d94c09e1d0d6cb15c9d964d6ff7c5f84 226 Gene3D G3DSA:1.10.150.240 17 89 8.2E-15 T 28-03-2018 IPR023198 Phosphoglycolate phosphatase, domain 2 CO689_RS11185 d94c09e1d0d6cb15c9d964d6ff7c5f84 226 TIGRFAM TIGR02254 YjjG/YfnB: noncanonical pyrimidine nucleotidase, YjjG family 3 226 1.4E-62 T 28-03-2018 IPR011951 HAD-superfamily hydrolase, subfamily IA, YjjG/YfnB GO:0016787 CO689_RS11185 d94c09e1d0d6cb15c9d964d6ff7c5f84 226 SUPERFAMILY SSF56784 2 226 2.66E-44 T 28-03-2018 IPR023214 HAD-like domain CO689_RS11185 d94c09e1d0d6cb15c9d964d6ff7c5f84 226 Pfam PF13419 Haloacid dehalogenase-like hydrolase 6 198 1.9E-22 T 28-03-2018 IPR023214 HAD-like domain CO689_RS00695 5247e1ec5d10600655d1eed1fff945ce 1530 Pfam PF17210 SdrD B-like domain 167 268 8.0E-31 T 28-03-2018 IPR033764 SD-repeat containing protein, B domain CO689_RS00695 5247e1ec5d10600655d1eed1fff945ce 1530 Pfam PF17210 SdrD B-like domain 56 159 1.9E-33 T 28-03-2018 IPR033764 SD-repeat containing protein, B domain CO689_RS00695 5247e1ec5d10600655d1eed1fff945ce 1530 Gene3D G3DSA:2.60.40.10 165 641 1.3E-20 T 28-03-2018 IPR013783 Immunoglobulin-like fold CO689_RS00695 5247e1ec5d10600655d1eed1fff945ce 1530 Gene3D G3DSA:2.60.40.10 52 164 4.0E-27 T 28-03-2018 IPR013783 Immunoglobulin-like fold CO689_RS00695 5247e1ec5d10600655d1eed1fff945ce 1530 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 1491 1523 1.7E-6 T 28-03-2018 CO689_RS00695 5247e1ec5d10600655d1eed1fff945ce 1530 Pfam PF00746 LPXTG cell wall anchor motif 1486 1526 4.2E-10 T 28-03-2018 IPR019948 Gram-positive LPXTG cell wall anchor CO689_RS00695 5247e1ec5d10600655d1eed1fff945ce 1530 SUPERFAMILY SSF49401 1 77 6.96E-10 T 28-03-2018 IPR008966 Adhesion domain CO689_RS00695 5247e1ec5d10600655d1eed1fff945ce 1530 SUPERFAMILY SSF117074 144 240 1.24E-22 T 28-03-2018 CO689_RS00695 5247e1ec5d10600655d1eed1fff945ce 1530 SUPERFAMILY SSF117074 54 137 6.15E-23 T 28-03-2018 CO689_RS06075 327ed351eef368ee980d205a0be5d82d 385 PIRSF PIRSF038994 2 384 3.0E-128 T 28-03-2018 IPR003764 N-acetylglucosamine-6-phosphate deacetylase GO:0006044|GO:0008448 KEGG: 00052+3.5.1.25|KEGG: 00520+3.5.1.25|MetaCyc: PWY-6906|MetaCyc: PWY-7077|MetaCyc: PWY-7395|Reactome: R-HSA-446210 CO689_RS06075 327ed351eef368ee980d205a0be5d82d 385 TIGRFAM TIGR00221 nagA: N-acetylglucosamine-6-phosphate deacetylase 3 380 1.6E-113 T 28-03-2018 IPR003764 N-acetylglucosamine-6-phosphate deacetylase GO:0006044|GO:0008448 KEGG: 00052+3.5.1.25|KEGG: 00520+3.5.1.25|MetaCyc: PWY-6906|MetaCyc: PWY-7077|MetaCyc: PWY-7395|Reactome: R-HSA-446210 CO689_RS06075 327ed351eef368ee980d205a0be5d82d 385 Gene3D G3DSA:3.20.20.140 70 353 6.7E-105 T 28-03-2018 CO689_RS06075 327ed351eef368ee980d205a0be5d82d 385 Pfam PF01979 Amidohydrolase family 51 380 2.4E-24 T 28-03-2018 IPR006680 Amidohydrolase-related GO:0016787 CO689_RS06075 327ed351eef368ee980d205a0be5d82d 385 SUPERFAMILY SSF51338 4 54 2.51E-19 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CO689_RS06075 327ed351eef368ee980d205a0be5d82d 385 SUPERFAMILY SSF51338 353 382 2.51E-19 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CO689_RS06075 327ed351eef368ee980d205a0be5d82d 385 SUPERFAMILY SSF51556 55 353 1.57E-94 T 28-03-2018 IPR032466 Metal-dependent hydrolase CO689_RS06075 327ed351eef368ee980d205a0be5d82d 385 Gene3D G3DSA:2.30.40.10 2 69 6.8E-16 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CO689_RS01800 0419a23037ef2ed65507e2feff4d73a8 508 Pfam PF00474 Sodium:solute symporter family 47 444 1.2E-92 T 28-03-2018 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 CO689_RS01800 0419a23037ef2ed65507e2feff4d73a8 508 TIGRFAM TIGR02121 Na_Pro_sym: sodium/proline symporter 16 505 6.0E-215 T 28-03-2018 IPR011851 Sodium/proline symporter GO:0005298|GO:0006814|GO:0015824|GO:0016021|GO:0031402 CO689_RS01800 0419a23037ef2ed65507e2feff4d73a8 508 TIGRFAM TIGR00813 sss: transporter, solute:sodium symporter (SSS) family 47 444 5.3E-84 T 28-03-2018 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 CO689_RS07020 0e6a9d54779409a02139f82a9ac931ff 378 Pfam PF00712 DNA polymerase III beta subunit, N-terminal domain 2 128 2.0E-40 T 28-03-2018 IPR022634 DNA polymerase III, beta chain, N-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CO689_RS07020 0e6a9d54779409a02139f82a9ac931ff 378 Gene3D G3DSA:3.10.150.10 131 257 1.2E-33 T 28-03-2018 CO689_RS07020 0e6a9d54779409a02139f82a9ac931ff 378 SMART SM00480 18 373 2.0E-176 T 28-03-2018 IPR001001 DNA polymerase III, beta chain GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CO689_RS07020 0e6a9d54779409a02139f82a9ac931ff 378 Gene3D G3DSA:3.10.150.10 258 378 4.7E-28 T 28-03-2018 CO689_RS07020 0e6a9d54779409a02139f82a9ac931ff 378 Pfam PF02767 DNA polymerase III beta subunit, central domain 137 252 3.6E-41 T 28-03-2018 IPR022637 DNA polymerase III, beta chain, central GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CO689_RS07020 0e6a9d54779409a02139f82a9ac931ff 378 TIGRFAM TIGR00663 dnan: DNA polymerase III, beta subunit 2 377 7.8E-115 T 28-03-2018 IPR001001 DNA polymerase III, beta chain GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CO689_RS07020 0e6a9d54779409a02139f82a9ac931ff 378 Gene3D G3DSA:3.10.150.10 1 130 6.0E-27 T 28-03-2018 CO689_RS07020 0e6a9d54779409a02139f82a9ac931ff 378 SUPERFAMILY SSF55979 2 128 2.55E-23 T 28-03-2018 CO689_RS07020 0e6a9d54779409a02139f82a9ac931ff 378 SUPERFAMILY SSF55979 136 252 8.05E-27 T 28-03-2018 CO689_RS07020 0e6a9d54779409a02139f82a9ac931ff 378 SUPERFAMILY SSF55979 255 377 1.24E-31 T 28-03-2018 CO689_RS07020 0e6a9d54779409a02139f82a9ac931ff 378 PIRSF PIRSF000804 2 378 4.8E-112 T 28-03-2018 IPR001001 DNA polymerase III, beta chain GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CO689_RS07020 0e6a9d54779409a02139f82a9ac931ff 378 Pfam PF02768 DNA polymerase III beta subunit, C-terminal domain 255 376 6.0E-38 T 28-03-2018 IPR022635 DNA polymerase III, beta chain, C-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CO689_RS04240 ae6e13a8365bfcfffd70f43040404518 699 SMART SM01086 604 691 1.2E-24 T 28-03-2018 IPR019489 Clp ATPase, C-terminal CO689_RS04240 ae6e13a8365bfcfffd70f43040404518 699 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 604 675 2.7E-20 T 28-03-2018 IPR019489 Clp ATPase, C-terminal CO689_RS04240 ae6e13a8365bfcfffd70f43040404518 699 Pfam PF07724 AAA domain (Cdc48 subfamily) 441 596 9.7E-43 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CO689_RS04240 ae6e13a8365bfcfffd70f43040404518 699 Gene3D G3DSA:1.10.8.60 259 392 2.3E-28 T 28-03-2018 CO689_RS04240 ae6e13a8365bfcfffd70f43040404518 699 SUPERFAMILY SSF52540 391 688 8.12E-70 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CO689_RS04240 ae6e13a8365bfcfffd70f43040404518 699 SMART SM00382 112 259 9.5E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain CO689_RS04240 ae6e13a8365bfcfffd70f43040404518 699 SMART SM00382 442 596 1.0E-8 T 28-03-2018 IPR003593 AAA+ ATPase domain CO689_RS04240 ae6e13a8365bfcfffd70f43040404518 699 Gene3D G3DSA:1.10.8.60 616 696 1.4E-20 T 28-03-2018 CO689_RS04240 ae6e13a8365bfcfffd70f43040404518 699 Gene3D G3DSA:3.40.50.300 71 258 9.1E-29 T 28-03-2018 CO689_RS04240 ae6e13a8365bfcfffd70f43040404518 699 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 117 253 1.3E-14 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CO689_RS04240 ae6e13a8365bfcfffd70f43040404518 699 Gene3D G3DSA:3.40.50.300 397 615 1.8E-39 T 28-03-2018 CO689_RS04240 ae6e13a8365bfcfffd70f43040404518 699 SUPERFAMILY SSF52540 74 339 2.39E-63 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CO689_RS04240 ae6e13a8365bfcfffd70f43040404518 699 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 521 539 3.9E-28 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 CO689_RS04240 ae6e13a8365bfcfffd70f43040404518 699 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 491 509 3.9E-28 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 CO689_RS04240 ae6e13a8365bfcfffd70f43040404518 699 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 446 464 3.9E-28 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 CO689_RS04240 ae6e13a8365bfcfffd70f43040404518 699 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 554 568 3.9E-28 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 CO689_RS11600 34e0d8c910fbee4590a6f12252678bde 284 Gene3D G3DSA:3.40.50.1980 1 120 4.6E-20 T 28-03-2018 CO689_RS11600 34e0d8c910fbee4590a6f12252678bde 284 Gene3D G3DSA:3.40.50.1980 121 282 3.3E-26 T 28-03-2018 CO689_RS11600 34e0d8c910fbee4590a6f12252678bde 284 Pfam PF01497 Periplasmic binding protein 20 257 2.8E-23 T 28-03-2018 IPR002491 ABC transporter periplasmic binding domain GO:0005488 CO689_RS11600 34e0d8c910fbee4590a6f12252678bde 284 SUPERFAMILY SSF53807 3 279 2.83E-46 T 28-03-2018 CO689_RS13835 e9c381cf0ce3be9bc32a5f87c03ff3d2 586 Gene3D G3DSA:3.20.20.60 1 110 2.5E-22 T 28-03-2018 CO689_RS13835 e9c381cf0ce3be9bc32a5f87c03ff3d2 586 Gene3D G3DSA:3.20.20.60 160 321 4.9E-61 T 28-03-2018 CO689_RS13835 e9c381cf0ce3be9bc32a5f87c03ff3d2 586 TIGRFAM TIGR01064 pyruv_kin: pyruvate kinase 2 473 1.8E-187 T 28-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CO689_RS13835 e9c381cf0ce3be9bc32a5f87c03ff3d2 586 Pfam PF02887 Pyruvate kinase, alpha/beta domain 359 471 1.6E-36 T 28-03-2018 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CO689_RS13835 e9c381cf0ce3be9bc32a5f87c03ff3d2 586 Gene3D G3DSA:3.50.30.10 472 580 1.9E-22 T 28-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 CO689_RS13835 e9c381cf0ce3be9bc32a5f87c03ff3d2 586 SUPERFAMILY SSF52009 466 584 6.02E-23 T 28-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 CO689_RS13835 e9c381cf0ce3be9bc32a5f87c03ff3d2 586 SUPERFAMILY SSF50800 71 167 7.15E-27 T 28-03-2018 IPR011037 Pyruvate kinase-like, insert domain CO689_RS13835 e9c381cf0ce3be9bc32a5f87c03ff3d2 586 Pfam PF00224 Pyruvate kinase, barrel domain 1 342 3.1E-151 T 28-03-2018 IPR015793 Pyruvate kinase, barrel GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CO689_RS13835 e9c381cf0ce3be9bc32a5f87c03ff3d2 586 Pfam PF00391 PEP-utilising enzyme, mobile domain 508 576 9.7E-15 T 28-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 CO689_RS13835 e9c381cf0ce3be9bc32a5f87c03ff3d2 586 Gene3D G3DSA:2.40.33.10 111 159 7.5E-23 T 28-03-2018 CO689_RS13835 e9c381cf0ce3be9bc32a5f87c03ff3d2 586 PRINTS PR01050 Pyruvate kinase family signature 269 293 1.4E-74 T 28-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CO689_RS13835 e9c381cf0ce3be9bc32a5f87c03ff3d2 586 PRINTS PR01050 Pyruvate kinase family signature 217 243 1.4E-74 T 28-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CO689_RS13835 e9c381cf0ce3be9bc32a5f87c03ff3d2 586 PRINTS PR01050 Pyruvate kinase family signature 313 329 1.4E-74 T 28-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CO689_RS13835 e9c381cf0ce3be9bc32a5f87c03ff3d2 586 PRINTS PR01050 Pyruvate kinase family signature 59 75 1.4E-74 T 28-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CO689_RS13835 e9c381cf0ce3be9bc32a5f87c03ff3d2 586 PRINTS PR01050 Pyruvate kinase family signature 294 312 1.4E-74 T 28-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CO689_RS13835 e9c381cf0ce3be9bc32a5f87c03ff3d2 586 PRINTS PR01050 Pyruvate kinase family signature 186 200 1.4E-74 T 28-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CO689_RS13835 e9c381cf0ce3be9bc32a5f87c03ff3d2 586 PRINTS PR01050 Pyruvate kinase family signature 244 268 1.4E-74 T 28-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CO689_RS13835 e9c381cf0ce3be9bc32a5f87c03ff3d2 586 SUPERFAMILY SSF52935 323 474 7.06E-42 T 28-03-2018 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CO689_RS13835 e9c381cf0ce3be9bc32a5f87c03ff3d2 586 ProSitePatterns PS00110 Pyruvate kinase active site signature. 215 227 - T 28-03-2018 IPR018209 Pyruvate kinase, active site GO:0004743|GO:0006096 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CO689_RS13835 e9c381cf0ce3be9bc32a5f87c03ff3d2 586 Gene3D G3DSA:3.40.1380.20 322 471 8.0E-54 T 28-03-2018 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CO689_RS13835 e9c381cf0ce3be9bc32a5f87c03ff3d2 586 SUPERFAMILY SSF51621 1 74 1.15E-99 T 28-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CO689_RS13835 e9c381cf0ce3be9bc32a5f87c03ff3d2 586 SUPERFAMILY SSF51621 156 343 1.15E-99 T 28-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CO689_RS07375 cd02feee1a539579645ffc1af251757d 199 Gene3D G3DSA:3.40.50.1820 1 199 7.4E-26 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CO689_RS07375 cd02feee1a539579645ffc1af251757d 199 SUPERFAMILY SSF53474 2 198 1.05E-44 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CO689_RS07375 cd02feee1a539579645ffc1af251757d 199 Pfam PF02230 Phospholipase/Carboxylesterase 8 194 4.0E-12 T 28-03-2018 IPR003140 Phospholipase/carboxylesterase/thioesterase GO:0016787 CO689_RS02185 6ff6ba604da0f7aa64e9a0aac74a1314 580 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 213 348 1.1E-44 T 28-03-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 CO689_RS02185 6ff6ba604da0f7aa64e9a0aac74a1314 580 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 444 463 - T 28-03-2018 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 CO689_RS02185 6ff6ba604da0f7aa64e9a0aac74a1314 580 Gene3D G3DSA:3.40.50.970 364 574 2.7E-52 T 28-03-2018 CO689_RS02185 6ff6ba604da0f7aa64e9a0aac74a1314 580 SUPERFAMILY SSF52467 208 373 1.64E-56 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CO689_RS02185 6ff6ba604da0f7aa64e9a0aac74a1314 580 Gene3D G3DSA:3.40.50.970 17 216 3.8E-61 T 28-03-2018 CO689_RS02185 6ff6ba604da0f7aa64e9a0aac74a1314 580 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 407 555 1.1E-50 T 28-03-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 CO689_RS02185 6ff6ba604da0f7aa64e9a0aac74a1314 580 TIGRFAM TIGR00118 acolac_lg: acetolactate synthase, large subunit, biosynthetic type 25 576 1.1E-224 T 28-03-2018 IPR012846 Acetolactate synthase, large subunit, biosynthetic GO:0000287|GO:0003984|GO:0009082|GO:0030976|GO:0050660 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 CO689_RS02185 6ff6ba604da0f7aa64e9a0aac74a1314 580 SUPERFAMILY SSF52518 385 577 4.47E-68 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CO689_RS02185 6ff6ba604da0f7aa64e9a0aac74a1314 580 SUPERFAMILY SSF52518 21 198 5.05E-60 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CO689_RS02185 6ff6ba604da0f7aa64e9a0aac74a1314 580 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 25 184 1.3E-56 T 28-03-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 CO689_RS02185 6ff6ba604da0f7aa64e9a0aac74a1314 580 Gene3D G3DSA:3.40.50.1220 217 363 2.0E-51 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CO689_RS02590 a583858e3ccf6a69b88fbbfc031efb91 221 Pfam PF11042 Protein of unknown function (DUF2750) 5 103 6.2E-5 T 28-03-2018 IPR021284 Protein of unknown function DUF2750 CO689_RS02590 a583858e3ccf6a69b88fbbfc031efb91 221 Pfam PF11042 Protein of unknown function (DUF2750) 118 219 1.5E-18 T 28-03-2018 IPR021284 Protein of unknown function DUF2750 CO689_RS10245 124e34708c39e901ed999a4ed16c2d2c 123 Gene3D G3DSA:1.10.490.10 2 123 1.6E-27 T 28-03-2018 CO689_RS10245 124e34708c39e901ed999a4ed16c2d2c 123 ProSitePatterns PS01213 Protozoan/cyanobacterial globins signature. 49 73 - T 28-03-2018 IPR019795 Globin, bacterial-like, conserved site GO:0015671|GO:0019825 CO689_RS10245 124e34708c39e901ed999a4ed16c2d2c 123 Pfam PF01152 Bacterial-like globin 6 119 3.9E-26 T 28-03-2018 IPR001486 Truncated hemoglobin GO:0019825 CO689_RS10245 124e34708c39e901ed999a4ed16c2d2c 123 SUPERFAMILY SSF46458 4 120 7.44E-31 T 28-03-2018 IPR009050 Globin-like CO689_RS01190 c4a6b3c5bb2010a804c371726514bd96 398 SUPERFAMILY SSF55973 5 111 4.32E-45 T 28-03-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CO689_RS01190 c4a6b3c5bb2010a804c371726514bd96 398 PIRSF PIRSF000497 1 397 4.5E-176 T 28-03-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CO689_RS01190 c4a6b3c5bb2010a804c371726514bd96 398 Hamap MF_00086 S-adenosylmethionine synthase [metK]. 4 396 57.949 T 28-03-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CO689_RS01190 c4a6b3c5bb2010a804c371726514bd96 398 Gene3D G3DSA:3.30.300.10 13 144 1.4E-41 T 28-03-2018 CO689_RS01190 c4a6b3c5bb2010a804c371726514bd96 398 SUPERFAMILY SSF55973 246 396 8.63E-71 T 28-03-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CO689_RS01190 c4a6b3c5bb2010a804c371726514bd96 398 SUPERFAMILY SSF55973 124 245 9.81E-51 T 28-03-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CO689_RS01190 c4a6b3c5bb2010a804c371726514bd96 398 Gene3D G3DSA:3.30.300.10 145 246 1.6E-45 T 28-03-2018 CO689_RS01190 c4a6b3c5bb2010a804c371726514bd96 398 ProSitePatterns PS00376 S-adenosylmethionine synthase signature 1. 128 138 - T 28-03-2018 IPR022631 S-adenosylmethionine synthetase, conserved site GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CO689_RS01190 c4a6b3c5bb2010a804c371726514bd96 398 Pfam PF02773 S-adenosylmethionine synthetase, C-terminal domain 246 385 1.7E-70 T 28-03-2018 IPR022630 S-adenosylmethionine synthetase, C-terminal GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CO689_RS01190 c4a6b3c5bb2010a804c371726514bd96 398 TIGRFAM TIGR01034 metK: methionine adenosyltransferase 7 395 1.8E-184 T 28-03-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CO689_RS01190 c4a6b3c5bb2010a804c371726514bd96 398 Pfam PF00438 S-adenosylmethionine synthetase, N-terminal domain 6 103 1.1E-41 T 28-03-2018 IPR022628 S-adenosylmethionine synthetase, N-terminal GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CO689_RS01190 c4a6b3c5bb2010a804c371726514bd96 398 ProSitePatterns PS00377 S-adenosylmethionine synthase signature 2. 272 280 - T 28-03-2018 IPR022631 S-adenosylmethionine synthetase, conserved site GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CO689_RS01190 c4a6b3c5bb2010a804c371726514bd96 398 Pfam PF02772 S-adenosylmethionine synthetase, central domain 127 244 4.5E-47 T 28-03-2018 IPR022629 S-adenosylmethionine synthetase, central domain GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CO689_RS01190 c4a6b3c5bb2010a804c371726514bd96 398 Gene3D G3DSA:3.30.300.10 259 398 2.2E-49 T 28-03-2018 CO689_RS11715 7da9485e47fcc3624cb1964618343bc6 1435 SUPERFAMILY SSF53098 419 874 6.37E-100 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CO689_RS11715 7da9485e47fcc3624cb1964618343bc6 1435 Pfam PF07733 Bacterial DNA polymerase III alpha subunit 822 1240 1.7E-96 T 28-03-2018 IPR011708 Bacterial DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CO689_RS11715 7da9485e47fcc3624cb1964618343bc6 1435 Gene3D G3DSA:1.20.5.140 569 588 1.5E-13 T 28-03-2018 CO689_RS11715 7da9485e47fcc3624cb1964618343bc6 1435 SMART SM00481 334 401 7.1E-27 T 28-03-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal CO689_RS11715 7da9485e47fcc3624cb1964618343bc6 1435 Pfam PF00929 Exonuclease 421 576 3.1E-41 T 28-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III CO689_RS11715 7da9485e47fcc3624cb1964618343bc6 1435 Pfam PF14579 Helix-hairpin-helix motif 1348 1424 6.1E-9 T 28-03-2018 IPR029460 DNA polymerase, helix-hairpin-helix motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CO689_RS11715 7da9485e47fcc3624cb1964618343bc6 1435 SMART SM00479 419 585 3.9E-55 T 28-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III CO689_RS11715 7da9485e47fcc3624cb1964618343bc6 1435 Gene3D G3DSA:3.20.20.150 320 414 8.8E-4 T 28-03-2018 CO689_RS11715 7da9485e47fcc3624cb1964618343bc6 1435 Gene3D G3DSA:2.40.50.140 220 319 5.9E-16 T 28-03-2018 CO689_RS11715 7da9485e47fcc3624cb1964618343bc6 1435 Pfam PF14480 DNA polymerase III polC-type N-terminus I 6 77 1.1E-13 T 28-03-2018 IPR028112 DNA polymerase III polC-type, N-terminal domain I KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CO689_RS11715 7da9485e47fcc3624cb1964618343bc6 1435 TIGRFAM TIGR00573 dnaq: exonuclease, DNA polymerase III, epsilon subunit family 413 634 2.2E-52 T 28-03-2018 IPR006054 DNA polymerase III epsilon subunit, exonuclease domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CO689_RS11715 7da9485e47fcc3624cb1964618343bc6 1435 Pfam PF02811 PHP domain 335 693 2.5E-53 T 28-03-2018 IPR004013 PHP domain GO:0003824 CO689_RS11715 7da9485e47fcc3624cb1964618343bc6 1435 Hamap MF_00356 DNA polymerase III PolC-type [polC]. 1 1435 434.393 T 28-03-2018 IPR006308 DNA polymerase III, alpha subunit, Gram-positive type GO:0003677|GO:0003887|GO:0005737|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CO689_RS11715 7da9485e47fcc3624cb1964618343bc6 1435 SUPERFAMILY SSF81585 1372 1419 1.24E-6 T 28-03-2018 CO689_RS11715 7da9485e47fcc3624cb1964618343bc6 1435 TIGRFAM TIGR01405 polC_Gram_pos: DNA polymerase III, alpha subunit, Gram-positive type 230 1433 0.0 T 28-03-2018 IPR006308 DNA polymerase III, alpha subunit, Gram-positive type GO:0003677|GO:0003887|GO:0005737|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CO689_RS11715 7da9485e47fcc3624cb1964618343bc6 1435 Pfam PF11490 DNA polymerase III polC-type N-terminus II 92 205 9.4E-17 T 28-03-2018 IPR024754 DNA polymerase III polC-like, N-terminal domain II KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CO689_RS11715 7da9485e47fcc3624cb1964618343bc6 1435 Gene3D G3DSA:1.10.150.280 1370 1419 2.6E-7 T 28-03-2018 CO689_RS11715 7da9485e47fcc3624cb1964618343bc6 1435 Gene3D G3DSA:3.30.420.10 415 568 1.0E-43 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CO689_RS12455 f4d5d684b49ecb6238a02c814e58e7cb 294 PRINTS PR00146 Dihydrodipicolinate synthase signature 37 58 2.5E-27 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CO689_RS12455 f4d5d684b49ecb6238a02c814e58e7cb 294 PRINTS PR00146 Dihydrodipicolinate synthase signature 130 147 2.5E-27 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CO689_RS12455 f4d5d684b49ecb6238a02c814e58e7cb 294 PRINTS PR00146 Dihydrodipicolinate synthase signature 73 91 2.5E-27 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CO689_RS12455 f4d5d684b49ecb6238a02c814e58e7cb 294 PRINTS PR00146 Dihydrodipicolinate synthase signature 105 121 2.5E-27 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CO689_RS12455 f4d5d684b49ecb6238a02c814e58e7cb 294 TIGRFAM TIGR00674 dapA: 4-hydroxy-tetrahydrodipicolinate synthase 8 287 1.6E-83 T 28-03-2018 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CO689_RS12455 f4d5d684b49ecb6238a02c814e58e7cb 294 SUPERFAMILY SSF51569 2 289 6.28E-84 T 28-03-2018 CO689_RS12455 f4d5d684b49ecb6238a02c814e58e7cb 294 Hamap MF_00418 4-hydroxy-tetrahydrodipicolinate synthase [dapA]. 4 288 54.493 T 28-03-2018 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CO689_RS12455 f4d5d684b49ecb6238a02c814e58e7cb 294 Pfam PF00701 Dihydrodipicolinate synthetase family 5 285 1.6E-74 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CO689_RS12455 f4d5d684b49ecb6238a02c814e58e7cb 294 SMART SM01130 4 290 3.1E-112 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CO689_RS12455 f4d5d684b49ecb6238a02c814e58e7cb 294 ProSitePatterns PS00666 Dihydrodipicolinate synthase signature 2. 135 165 - T 28-03-2018 IPR020625 Schiff base-forming aldolase, active site GO:0008152|GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|Reactome: R-HSA-389661 CO689_RS12455 f4d5d684b49ecb6238a02c814e58e7cb 294 PIRSF PIRSF001365 2 293 9.7E-83 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CO689_RS12455 f4d5d684b49ecb6238a02c814e58e7cb 294 Gene3D G3DSA:3.20.20.70 3 294 8.5E-85 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CO689_RS08355 83404dedfe5f0c71a7a0938291b62d1e 315 Pfam PF01032 FecCD transport family 9 308 6.6E-62 T 28-03-2018 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 CO689_RS08355 83404dedfe5f0c71a7a0938291b62d1e 315 Gene3D G3DSA:1.10.3470.10 3 315 7.3E-43 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CO689_RS08355 83404dedfe5f0c71a7a0938291b62d1e 315 SUPERFAMILY SSF81345 6 307 1.96E-53 T 28-03-2018 IPR029022 ABC transporter, BtuC-like CO689_RS03260 475d09485437b582f36067f017c0c898 243 PIRSF PIRSF006648 9 241 7.0E-20 T 28-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 CO689_RS03260 475d09485437b582f36067f017c0c898 243 Pfam PF01061 ABC-2 type transporter 9 199 6.9E-14 T 28-03-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 CO689_RS13150 90883622a2d23f64a40c1c034e489fc1 444 Gene3D G3DSA:3.90.350.10 142 290 2.9E-6 T 28-03-2018 IPR014736 Transposase, Tn5-like, core CO689_RS13150 90883622a2d23f64a40c1c034e489fc1 444 Pfam PF13751 Transposase DDE domain 321 439 6.2E-22 T 28-03-2018 IPR025668 Transposase DDE domain CO689_RS13150 90883622a2d23f64a40c1c034e489fc1 444 Pfam PF05598 Transposase domain (DUF772) 52 127 3.1E-21 T 28-03-2018 IPR008490 Transposase InsH, N-terminal CO689_RS01100 50218be5f98a79e9639ebdc3ccbfaefe 276 SUPERFAMILY SSF53474 6 258 1.8E-26 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CO689_RS01100 50218be5f98a79e9639ebdc3ccbfaefe 276 Pfam PF12146 Serine aminopeptidase, S33 9 244 1.2E-44 T 28-03-2018 IPR022742 Serine aminopeptidase, S33 CO689_RS01100 50218be5f98a79e9639ebdc3ccbfaefe 276 Gene3D G3DSA:3.40.50.1820 1 263 1.2E-24 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CO689_RS01100 50218be5f98a79e9639ebdc3ccbfaefe 276 PRINTS PR00111 Alpha/beta hydrolase fold signature 86 99 1.2E-6 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CO689_RS01100 50218be5f98a79e9639ebdc3ccbfaefe 276 PRINTS PR00111 Alpha/beta hydrolase fold signature 199 213 1.2E-6 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CO689_RS01100 50218be5f98a79e9639ebdc3ccbfaefe 276 PRINTS PR00111 Alpha/beta hydrolase fold signature 38 53 1.2E-6 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CO689_RS04965 0b3202e061e3c64971eb312574be863d 373 Pfam PF12698 ABC-2 family transporter protein 18 364 2.4E-41 T 28-03-2018 CO689_RS13455 a5cbe1cab50f3d2cd182fa26cb8adf71 380 SUPERFAMILY SSF53383 3 374 1.71E-100 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CO689_RS13455 a5cbe1cab50f3d2cd182fa26cb8adf71 380 Gene3D G3DSA:3.90.1150.10 250 366 5.2E-27 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CO689_RS13455 a5cbe1cab50f3d2cd182fa26cb8adf71 380 Pfam PF00266 Aminotransferase class-V 3 365 7.2E-79 T 28-03-2018 IPR000192 Aminotransferase class V domain CO689_RS13455 a5cbe1cab50f3d2cd182fa26cb8adf71 380 Gene3D G3DSA:3.40.640.10 11 249 7.5E-61 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CO689_RS13455 a5cbe1cab50f3d2cd182fa26cb8adf71 380 PIRSF PIRSF005572 1 380 1.6E-121 T 28-03-2018 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250 CO689_RS01745 668caa1425e088f160e22ef66a4def34 254 Gene3D G3DSA:3.90.230.10 1 252 2.1E-70 T 28-03-2018 CO689_RS01745 668caa1425e088f160e22ef66a4def34 254 Hamap MF_01974 Methionine aminopeptidase [map]. 1 249 36.186 T 28-03-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 CO689_RS01745 668caa1425e088f160e22ef66a4def34 254 SUPERFAMILY SSF55920 2 248 3.14E-73 T 28-03-2018 IPR000994 Peptidase M24 CO689_RS01745 668caa1425e088f160e22ef66a4def34 254 TIGRFAM TIGR00500 met_pdase_I: methionine aminopeptidase, type I 1 248 3.8E-85 T 28-03-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 CO689_RS01745 668caa1425e088f160e22ef66a4def34 254 PRINTS PR00599 Methionine aminopeptidase-1 signature 88 104 2.7E-20 T 28-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 CO689_RS01745 668caa1425e088f160e22ef66a4def34 254 PRINTS PR00599 Methionine aminopeptidase-1 signature 191 203 2.7E-20 T 28-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 CO689_RS01745 668caa1425e088f160e22ef66a4def34 254 PRINTS PR00599 Methionine aminopeptidase-1 signature 66 79 2.7E-20 T 28-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 CO689_RS01745 668caa1425e088f160e22ef66a4def34 254 PRINTS PR00599 Methionine aminopeptidase-1 signature 159 171 2.7E-20 T 28-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 CO689_RS01745 668caa1425e088f160e22ef66a4def34 254 Pfam PF00557 Metallopeptidase family M24 13 240 4.6E-49 T 28-03-2018 IPR000994 Peptidase M24 CO689_RS03010 682ebcef292c3cc6df450000ff1a75be 268 Gene3D G3DSA:3.40.50.300 2 242 2.7E-67 T 28-03-2018 CO689_RS03010 682ebcef292c3cc6df450000ff1a75be 268 SMART SM00382 33 218 7.5E-16 T 28-03-2018 IPR003593 AAA+ ATPase domain CO689_RS03010 682ebcef292c3cc6df450000ff1a75be 268 SUPERFAMILY SSF52540 6 234 2.22E-62 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CO689_RS03010 682ebcef292c3cc6df450000ff1a75be 268 Pfam PF00005 ABC transporter 24 170 6.6E-33 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CO689_RS03010 682ebcef292c3cc6df450000ff1a75be 268 ProSitePatterns PS00211 ABC transporters family signature. 142 156 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CO689_RS03010 682ebcef292c3cc6df450000ff1a75be 268 TIGRFAM TIGR04520 ECF_ATPase_1: energy-coupling factor transporter ATPase 7 254 2.5E-104 T 28-03-2018 IPR030947 Energy-coupling factor transporter ATP-binding protein EcfA1 CO689_RS10640 b00bd5404e81c0fe5e7b4ef05b1bb0da 315 Pfam PF00294 pfkB family carbohydrate kinase 18 282 7.6E-45 T 28-03-2018 IPR011611 Carbohydrate kinase PfkB CO689_RS10640 b00bd5404e81c0fe5e7b4ef05b1bb0da 315 SUPERFAMILY SSF53613 6 287 3.12E-61 T 28-03-2018 IPR029056 Ribokinase-like CO689_RS10640 b00bd5404e81c0fe5e7b4ef05b1bb0da 315 Gene3D G3DSA:2.20.150.10 12 45 1.0E-13 T 28-03-2018 IPR023314 Tagatose-6-phosphate kinase/1-phosphofructokinase N-terminal domain CO689_RS10640 b00bd5404e81c0fe5e7b4ef05b1bb0da 315 TIGRFAM TIGR03168 1-PFK: hexose kinase, 1-phosphofructokinase family 6 309 3.3E-81 T 28-03-2018 IPR017583 Tagatose/fructose phosphokinase GO:0005975|GO:0016773 CO689_RS10640 b00bd5404e81c0fe5e7b4ef05b1bb0da 315 Gene3D G3DSA:3.40.1190.20 46 312 2.5E-38 T 28-03-2018 IPR029056 Ribokinase-like CO689_RS10640 b00bd5404e81c0fe5e7b4ef05b1bb0da 315 PIRSF PIRSF000535 2 311 3.9E-89 T 28-03-2018 IPR017583 Tagatose/fructose phosphokinase GO:0005975|GO:0016773 CO689_RS10640 b00bd5404e81c0fe5e7b4ef05b1bb0da 315 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 249 262 - T 28-03-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 CO689_RS02200 d1184982cf0621f950350b95c382e2a5 510 Gene3D G3DSA:3.20.20.70 1 327 2.6E-104 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CO689_RS02200 d1184982cf0621f950350b95c382e2a5 510 SUPERFAMILY SSF51569 2 290 1.45E-93 T 28-03-2018 CO689_RS02200 d1184982cf0621f950350b95c382e2a5 510 TIGRFAM TIGR00973 leuA_bact: 2-isopropylmalate synthase 4 494 2.2E-198 T 28-03-2018 IPR005671 2-isopropylmalate synthase, bacterial-type GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 CO689_RS02200 d1184982cf0621f950350b95c382e2a5 510 SMART SM00917 368 499 4.2E-25 T 28-03-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 CO689_RS02200 d1184982cf0621f950350b95c382e2a5 510 SUPERFAMILY SSF110921 402 495 1.44E-17 T 28-03-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 CO689_RS02200 d1184982cf0621f950350b95c382e2a5 510 Pfam PF08502 LeuA allosteric (dimerisation) domain 369 496 1.7E-31 T 28-03-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 CO689_RS02200 d1184982cf0621f950350b95c382e2a5 510 Hamap MF_01025 2-isopropylmalate synthase [leuA]. 1 508 40.183 T 28-03-2018 IPR005671 2-isopropylmalate synthase, bacterial-type GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 CO689_RS02200 d1184982cf0621f950350b95c382e2a5 510 Pfam PF00682 HMGL-like 4 272 4.8E-93 T 28-03-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 CO689_RS12945 18649bee0cd24e7a6ea26aecdde8f7cf 325 Pfam PF11728 Putative aromatic acid exporter C-terminal domain 151 314 1.3E-37 T 28-03-2018 IPR021062 Putative aromatic acid exporter, C-terminal CO689_RS12945 18649bee0cd24e7a6ea26aecdde8f7cf 325 Pfam PF06081 Aromatic acid exporter family member 1 8 147 1.7E-42 T 28-03-2018 IPR010343 Aromatic acid exporter family member 1 CO689_RS03915 decced517da9631678f397156182b735 383 SUPERFAMILY SSF53901 4 258 4.28E-74 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CO689_RS03915 decced517da9631678f397156182b735 383 Pfam PF00108 Thiolase, N-terminal domain 4 251 1.4E-85 T 28-03-2018 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 CO689_RS03915 decced517da9631678f397156182b735 383 Gene3D G3DSA:3.40.47.10 1 254 5.7E-53 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CO689_RS03915 decced517da9631678f397156182b735 383 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 6 379 1.5E-133 T 28-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 CO689_RS03915 decced517da9631678f397156182b735 383 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 84 102 - T 28-03-2018 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0008152|GO:0016747 CO689_RS03915 decced517da9631678f397156182b735 383 ProSitePatterns PS00099 Thiolases active site. 363 376 - T 28-03-2018 IPR020610 Thiolase, active site GO:0008152|GO:0016747 CO689_RS03915 decced517da9631678f397156182b735 383 PIRSF PIRSF000429 1 383 1.3E-124 T 28-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 CO689_RS03915 decced517da9631678f397156182b735 383 ProSitePatterns PS00737 Thiolases signature 2. 328 344 - T 28-03-2018 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 CO689_RS03915 decced517da9631678f397156182b735 383 SUPERFAMILY SSF53901 262 380 7.84E-38 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CO689_RS03915 decced517da9631678f397156182b735 383 Gene3D G3DSA:3.40.47.10 255 379 6.0E-29 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CO689_RS03915 decced517da9631678f397156182b735 383 Pfam PF02803 Thiolase, C-terminal domain 261 380 5.3E-44 T 28-03-2018 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 CO689_RS03430 55d0a50cad209cdb3526ff30b4acbc99 158 Pfam PF03073 TspO/MBR family 15 152 6.5E-34 T 28-03-2018 IPR004307 TspO/MBR-related protein GO:0016021 CO689_RS03430 55d0a50cad209cdb3526ff30b4acbc99 158 PIRSF PIRSF005859 2 156 5.3E-33 T 28-03-2018 IPR004307 TspO/MBR-related protein GO:0016021 CO689_RS04915 f36d96e2742e5f325fe2ff9b31f87925 411 Pfam PF02274 Amidinotransferase 20 408 5.2E-114 T 28-03-2018 CO689_RS04915 f36d96e2742e5f325fe2ff9b31f87925 411 Gene3D G3DSA:3.75.10.10 5 409 1.5E-100 T 28-03-2018 CO689_RS04915 f36d96e2742e5f325fe2ff9b31f87925 411 PIRSF PIRSF006356 1 411 2.7E-168 T 28-03-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 CO689_RS04915 f36d96e2742e5f325fe2ff9b31f87925 411 PRINTS PR01466 Bacterial arginine deiminase signature 347 364 8.3E-55 T 28-03-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 CO689_RS04915 f36d96e2742e5f325fe2ff9b31f87925 411 PRINTS PR01466 Bacterial arginine deiminase signature 4 24 8.3E-55 T 28-03-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 CO689_RS04915 f36d96e2742e5f325fe2ff9b31f87925 411 PRINTS PR01466 Bacterial arginine deiminase signature 180 195 8.3E-55 T 28-03-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 CO689_RS04915 f36d96e2742e5f325fe2ff9b31f87925 411 PRINTS PR01466 Bacterial arginine deiminase signature 390 408 8.3E-55 T 28-03-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 CO689_RS04915 f36d96e2742e5f325fe2ff9b31f87925 411 PRINTS PR01466 Bacterial arginine deiminase signature 367 381 8.3E-55 T 28-03-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 CO689_RS04915 f36d96e2742e5f325fe2ff9b31f87925 411 PRINTS PR01466 Bacterial arginine deiminase signature 152 170 8.3E-55 T 28-03-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 CO689_RS04915 f36d96e2742e5f325fe2ff9b31f87925 411 TIGRFAM TIGR01078 arcA: arginine deiminase 6 411 2.4E-163 T 28-03-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 CO689_RS04915 f36d96e2742e5f325fe2ff9b31f87925 411 SUPERFAMILY SSF55909 4 411 2.55E-132 T 28-03-2018 CO689_RS04915 f36d96e2742e5f325fe2ff9b31f87925 411 Hamap MF_00242 Arginine deiminase [arcA]. 3 411 47.152 T 28-03-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 CO689_RS00580 aee48765115e69c10e668eb90bfbdf1e 126 Gene3D G3DSA:1.10.4040.10 73 122 6.4E-15 T 28-03-2018 CO689_RS00580 aee48765115e69c10e668eb90bfbdf1e 126 PIRSF PIRSF019455 1 126 1.4E-31 T 28-03-2018 IPR005650 BlaI transcriptional regulatory family GO:0003677|GO:0045892 CO689_RS00580 aee48765115e69c10e668eb90bfbdf1e 126 Gene3D G3DSA:1.10.10.10 9 72 2.6E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS00580 aee48765115e69c10e668eb90bfbdf1e 126 SUPERFAMILY SSF46785 6 125 3.34E-30 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS00580 aee48765115e69c10e668eb90bfbdf1e 126 Pfam PF03965 Penicillinase repressor 8 121 6.9E-35 T 28-03-2018 IPR005650 BlaI transcriptional regulatory family GO:0003677|GO:0045892 CO689_RS10060 01df29b3726110a890b772ea1736fab1 396 Gene3D G3DSA:3.90.1150.10 1 168 2.0E-41 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CO689_RS10060 01df29b3726110a890b772ea1736fab1 396 Gene3D G3DSA:3.40.640.10 169 293 1.8E-44 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CO689_RS10060 01df29b3726110a890b772ea1736fab1 396 PIRSF PIRSF000521 170 396 2.0E-33 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CO689_RS10060 01df29b3726110a890b772ea1736fab1 396 PIRSF PIRSF000521 2 159 1.1E-10 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CO689_RS10060 01df29b3726110a890b772ea1736fab1 396 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 223 260 - T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CO689_RS10060 01df29b3726110a890b772ea1736fab1 396 Gene3D G3DSA:3.90.1150.10 294 396 8.4E-30 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CO689_RS10060 01df29b3726110a890b772ea1736fab1 396 Hamap MF_01689 Ornithine aminotransferase [rocD]. 4 396 65.32 T 28-03-2018 IPR034757 Ornithine aminotransferase, bacterial type GO:0004587 KEGG: 00330+2.6.1.13|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|MetaCyc: PWY-6922 CO689_RS10060 01df29b3726110a890b772ea1736fab1 396 SUPERFAMILY SSF53383 2 395 1.24E-124 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CO689_RS10060 01df29b3726110a890b772ea1736fab1 396 TIGRFAM TIGR01885 Orn_aminotrans: ornithine--oxo-acid transaminase 4 395 3.2E-158 T 28-03-2018 IPR010164 Ornithine aminotransferase GO:0004587 KEGG: 00330+2.6.1.13|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|MetaCyc: PWY-6922|Reactome: R-HSA-70614 CO689_RS10060 01df29b3726110a890b772ea1736fab1 396 Pfam PF00202 Aminotransferase class-III 15 394 3.2E-132 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CO689_RS10060 01df29b3726110a890b772ea1736fab1 396 Hamap MF_01107 Acetylornithine/succinyldiaminopimelate aminotransferase [argD]. 12 396 37.935 T 28-03-2018 IPR004636 Acetylornithine/Succinylornithine transaminase family GO:0006525|GO:0008483 CO689_RS12970 eaebe13c3bf0866555c3c25c98dce750 474 SUPERFAMILY SSF55424 348 473 4.98E-31 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CO689_RS12970 eaebe13c3bf0866555c3c25c98dce750 474 Gene3D G3DSA:3.30.390.30 345 473 8.0E-33 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CO689_RS12970 eaebe13c3bf0866555c3c25c98dce750 474 Gene3D G3DSA:3.50.50.60 2 173 3.8E-25 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CO689_RS12970 eaebe13c3bf0866555c3c25c98dce750 474 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 7 29 4.2E-65 T 28-03-2018 CO689_RS12970 eaebe13c3bf0866555c3c25c98dce750 474 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 147 156 4.2E-65 T 28-03-2018 CO689_RS12970 eaebe13c3bf0866555c3c25c98dce750 474 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 269 283 4.2E-65 T 28-03-2018 CO689_RS12970 eaebe13c3bf0866555c3c25c98dce750 474 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 416 431 4.2E-65 T 28-03-2018 CO689_RS12970 eaebe13c3bf0866555c3c25c98dce750 474 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 348 369 4.2E-65 T 28-03-2018 CO689_RS12970 eaebe13c3bf0866555c3c25c98dce750 474 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 183 208 4.2E-65 T 28-03-2018 CO689_RS12970 eaebe13c3bf0866555c3c25c98dce750 474 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 39 54 4.2E-65 T 28-03-2018 CO689_RS12970 eaebe13c3bf0866555c3c25c98dce750 474 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 312 319 4.2E-65 T 28-03-2018 CO689_RS12970 eaebe13c3bf0866555c3c25c98dce750 474 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 438 458 4.2E-65 T 28-03-2018 CO689_RS12970 eaebe13c3bf0866555c3c25c98dce750 474 TIGRFAM TIGR01350 lipoamide_DH: dihydrolipoyl dehydrogenase 5 473 1.1E-154 T 28-03-2018 IPR006258 Dihydrolipoamide dehydrogenase GO:0004148|GO:0050660|GO:0055114 KEGG: 00010+1.8.1.4|KEGG: 00020+1.8.1.4|KEGG: 00260+1.8.1.4|KEGG: 00280+1.8.1.4|KEGG: 00620+1.8.1.4|KEGG: 00640+1.8.1.4|MetaCyc: PWY-5046|MetaCyc: PWY-5084|Reactome: R-HSA-204174|Reactome: R-HSA-389661|Reactome: R-HSA-5362517|Reactome: R-HSA-6783984|Reactome: R-HSA-70268|Reactome: R-HSA-70895|Reactome: R-HSA-71064|Reactome: R-HSA-71403 CO689_RS12970 eaebe13c3bf0866555c3c25c98dce750 474 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 352 463 1.2E-26 T 28-03-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 CO689_RS12970 eaebe13c3bf0866555c3c25c98dce750 474 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 40 50 - T 28-03-2018 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 CO689_RS12970 eaebe13c3bf0866555c3c25c98dce750 474 SUPERFAMILY SSF51905 89 341 1.99E-52 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CO689_RS12970 eaebe13c3bf0866555c3c25c98dce750 474 SUPERFAMILY SSF51905 1 62 1.99E-52 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CO689_RS12970 eaebe13c3bf0866555c3c25c98dce750 474 Gene3D G3DSA:3.40.50.720 174 344 2.6E-35 T 28-03-2018 CO689_RS12970 eaebe13c3bf0866555c3c25c98dce750 474 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 8 27 6.5E-38 T 28-03-2018 CO689_RS12970 eaebe13c3bf0866555c3c25c98dce750 474 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 144 162 6.5E-38 T 28-03-2018 CO689_RS12970 eaebe13c3bf0866555c3c25c98dce750 474 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 268 284 6.5E-38 T 28-03-2018 CO689_RS12970 eaebe13c3bf0866555c3c25c98dce750 474 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 297 319 6.5E-38 T 28-03-2018 CO689_RS12970 eaebe13c3bf0866555c3c25c98dce750 474 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 183 201 6.5E-38 T 28-03-2018 CO689_RS12970 eaebe13c3bf0866555c3c25c98dce750 474 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 6 332 2.5E-63 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CO689_RS12970 eaebe13c3bf0866555c3c25c98dce750 474 PIRSF PIRSF000350 1 473 4.8E-79 T 28-03-2018 CO689_RS02985 2081cd9d70f9f6db3461cc84e6a2ab20 132 SUPERFAMILY SSF54211 8 132 1.59E-48 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CO689_RS02985 2081cd9d70f9f6db3461cc84e6a2ab20 132 Gene3D G3DSA:3.30.230.10 5 132 5.4E-52 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CO689_RS02985 2081cd9d70f9f6db3461cc84e6a2ab20 132 Hamap MF_00532_B 30S ribosomal protein S9 [rpsI]. 3 132 33.845 T 28-03-2018 IPR023035 Ribosomal protein S9, bacterial/plastid CO689_RS02985 2081cd9d70f9f6db3461cc84e6a2ab20 132 ProSitePatterns PS00360 Ribosomal protein S9 signature. 71 89 - T 28-03-2018 IPR020574 Ribosomal protein S9, conserved site GO:0003735|GO:0005840|GO:0006412 CO689_RS02985 2081cd9d70f9f6db3461cc84e6a2ab20 132 Pfam PF00380 Ribosomal protein S9/S16 12 132 1.3E-46 T 28-03-2018 IPR000754 Ribosomal protein S9 GO:0003735|GO:0005840|GO:0006412 CO689_RS10620 111dde8c0172045ba8bdc3285ac1885a 133 Gene3D G3DSA:3.40.50.2300 1 130 1.0E-36 T 28-03-2018 CO689_RS10620 111dde8c0172045ba8bdc3285ac1885a 133 TIGRFAM TIGR02691 arsC_pI258_fam: arsenate reductase (thioredoxin) 6 127 4.4E-59 T 28-03-2018 IPR014064 Arsenate reductase ArsC GO:0004725|GO:0030612|GO:0046685 CO689_RS10620 111dde8c0172045ba8bdc3285ac1885a 133 SUPERFAMILY SSF52788 6 129 8.11E-41 T 28-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily CO689_RS10620 111dde8c0172045ba8bdc3285ac1885a 133 SMART SM00226 4 131 4.3E-48 T 28-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily CO689_RS10620 111dde8c0172045ba8bdc3285ac1885a 133 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 6 128 3.7E-21 T 28-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily CO689_RS10810 3d34e97152da645e0538adf90203c428 573 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 501 513 6.6E-32 T 28-03-2018 CO689_RS10810 3d34e97152da645e0538adf90203c428 573 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 294 313 6.6E-32 T 28-03-2018 CO689_RS10810 3d34e97152da645e0538adf90203c428 573 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 465 480 6.6E-32 T 28-03-2018 CO689_RS10810 3d34e97152da645e0538adf90203c428 573 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 448 463 6.6E-32 T 28-03-2018 CO689_RS10810 3d34e97152da645e0538adf90203c428 573 Pfam PF00391 PEP-utilising enzyme, mobile domain 154 226 6.5E-23 T 28-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 CO689_RS10810 3d34e97152da645e0538adf90203c428 573 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 251 541 4.4E-131 T 28-03-2018 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 CO689_RS10810 3d34e97152da645e0538adf90203c428 573 SUPERFAMILY SSF52009 126 247 1.83E-37 T 28-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 CO689_RS10810 3d34e97152da645e0538adf90203c428 573 SUPERFAMILY SSF51621 250 550 2.62E-113 T 28-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CO689_RS10810 3d34e97152da645e0538adf90203c428 573 Gene3D G3DSA:3.20.20.60 256 573 8.4E-107 T 28-03-2018 CO689_RS10810 3d34e97152da645e0538adf90203c428 573 Pfam PF05524 PEP-utilising enzyme, N-terminal 6 127 4.7E-33 T 28-03-2018 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 CO689_RS10810 3d34e97152da645e0538adf90203c428 573 ProSitePatterns PS00742 PEP-utilizing enzymes signature 2. 448 466 - T 28-03-2018 IPR023151 PEP-utilising enzyme, conserved site GO:0016772 CO689_RS10810 3d34e97152da645e0538adf90203c428 573 Gene3D G3DSA:1.10.274.10 27 135 1.5E-37 T 28-03-2018 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 CO689_RS10810 3d34e97152da645e0538adf90203c428 573 SUPERFAMILY SSF47831 24 144 4.05E-36 T 28-03-2018 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 CO689_RS10810 3d34e97152da645e0538adf90203c428 573 Gene3D G3DSA:3.50.30.10 136 255 1.9E-30 T 28-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 CO689_RS10810 3d34e97152da645e0538adf90203c428 573 TIGRFAM TIGR01417 PTS_I_fam: phosphoenolpyruvate-protein phosphotransferase 5 567 5.3E-244 T 28-03-2018 IPR006318 Phosphotransferase system, enzyme I-like GO:0016772 CO689_RS10810 3d34e97152da645e0538adf90203c428 573 ProSitePatterns PS00370 PEP-utilizing enzymes phosphorylation site signature. 185 196 - T 28-03-2018 IPR018274 PEP-utilising enzyme, active site GO:0016310|GO:0016772 CO689_RS10810 3d34e97152da645e0538adf90203c428 573 PIRSF PIRSF000732 1 573 2.6E-226 T 28-03-2018 IPR024692 Phosphotransferase system, enzyme I GO:0008965|GO:0009401 CO689_RS13385 51c0edd5d8c760e7b62973cc0850f48b 175 Pfam PF13419 Haloacid dehalogenase-like hydrolase 45 139 1.2E-10 T 28-03-2018 IPR023214 HAD-like domain CO689_RS13385 51c0edd5d8c760e7b62973cc0850f48b 175 TIGRFAM TIGR01662 HAD-SF-IIIA: HAD hydrolase, family IIIA 31 141 2.1E-24 T 28-03-2018 IPR006549 HAD-superfamily hydrolase,subfamily IIIA Reactome: R-HSA-5649702 CO689_RS13385 51c0edd5d8c760e7b62973cc0850f48b 175 SUPERFAMILY SSF56784 6 153 5.09E-26 T 28-03-2018 IPR023214 HAD-like domain CO689_RS13385 51c0edd5d8c760e7b62973cc0850f48b 175 TIGRFAM TIGR01668 YqeG_hyp_ppase: HAD phosphatase, family IIIA 8 168 4.6E-47 T 28-03-2018 IPR010021 HAD-superfamily phosphatase, YqeG-like CO689_RS13385 51c0edd5d8c760e7b62973cc0850f48b 175 Gene3D G3DSA:3.40.50.1000 18 151 2.9E-24 T 28-03-2018 IPR023214 HAD-like domain CO689_RS12265 6b4ffd99dc98d9d755aedb4b8bc52126 692 TIGRFAM TIGR00826 EIIB_glc: PTS system, glucose-like IIB component 420 502 9.6E-21 T 28-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 CO689_RS12265 6b4ffd99dc98d9d755aedb4b8bc52126 692 TIGRFAM TIGR00830 PTBA: PTS system, glucose subfamily, IIA component 547 667 9.0E-46 T 28-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 CO689_RS12265 6b4ffd99dc98d9d755aedb4b8bc52126 692 Pfam PF02378 Phosphotransferase system, EIIC 16 359 2.2E-99 T 28-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 CO689_RS12265 6b4ffd99dc98d9d755aedb4b8bc52126 692 TIGRFAM TIGR02002 PTS-II-BC-glcB: PTS system, glucose-specific IIBC component 5 518 1.1E-264 T 28-03-2018 IPR011299 PTS system glucose-specific IIBC component GO:0005355|GO:0015758|GO:0016021 CO689_RS12265 6b4ffd99dc98d9d755aedb4b8bc52126 692 Pfam PF00367 phosphotransferase system, EIIB 446 478 4.8E-14 T 28-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 CO689_RS12265 6b4ffd99dc98d9d755aedb4b8bc52126 692 ProSitePatterns PS00371 PTS EIIA domains phosphorylation site signature 1. 609 621 - T 28-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 CO689_RS12265 6b4ffd99dc98d9d755aedb4b8bc52126 692 Gene3D G3DSA:3.30.1360.60 441 516 8.0E-26 T 28-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 CO689_RS12265 6b4ffd99dc98d9d755aedb4b8bc52126 692 ProSitePatterns PS01035 PTS EIIB domains cysteine phosphorylation site signature. 456 473 - T 28-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 CO689_RS12265 6b4ffd99dc98d9d755aedb4b8bc52126 692 Gene3D G3DSA:2.70.70.10 533 692 1.8E-58 T 28-03-2018 CO689_RS12265 6b4ffd99dc98d9d755aedb4b8bc52126 692 SUPERFAMILY SSF55604 445 516 1.7E-20 T 28-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 CO689_RS12265 6b4ffd99dc98d9d755aedb4b8bc52126 692 Pfam PF00358 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 546 669 6.1E-52 T 28-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 CO689_RS12265 6b4ffd99dc98d9d755aedb4b8bc52126 692 SUPERFAMILY SSF51261 543 689 1.45E-55 T 28-03-2018 IPR011055 Duplicated hybrid motif CO689_RS10690 a80eb24bfc8ff36d7bde0bce976a1ddf 370 Gene3D G3DSA:1.10.287.90 20 109 1.1E-22 T 28-03-2018 CO689_RS10690 a80eb24bfc8ff36d7bde0bce976a1ddf 370 Gene3D G3DSA:2.60.40.420 110 266 4.2E-36 T 28-03-2018 IPR008972 Cupredoxin CO689_RS10690 a80eb24bfc8ff36d7bde0bce976a1ddf 370 TIGRFAM TIGR01432 QOXA: cytochrome aa3 quinol oxidase, subunit II 8 230 6.9E-110 T 28-03-2018 IPR006332 Quinol oxidase subunit II GO:0009486|GO:0016021|GO:0016682|GO:0055114 CO689_RS10690 a80eb24bfc8ff36d7bde0bce976a1ddf 370 SUPERFAMILY SSF49503 114 244 6.57E-37 T 28-03-2018 IPR008972 Cupredoxin CO689_RS10690 a80eb24bfc8ff36d7bde0bce976a1ddf 370 SUPERFAMILY SSF81464 14 110 5.07E-22 T 28-03-2018 IPR011759 Cytochrome C oxidase subunit II, transmembrane domain GO:0016021|GO:0022900 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CO689_RS10690 a80eb24bfc8ff36d7bde0bce976a1ddf 370 Pfam PF02790 Cytochrome C oxidase subunit II, transmembrane domain 31 102 1.1E-7 T 28-03-2018 IPR011759 Cytochrome C oxidase subunit II, transmembrane domain GO:0016021|GO:0022900 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CO689_RS10690 a80eb24bfc8ff36d7bde0bce976a1ddf 370 PIRSF PIRSF000292 307 366 540.0 T 28-03-2018 IPR006333 Cytochrome o ubiquinol oxidase subunit II GO:0016020|GO:0016682|GO:0055114 CO689_RS10690 a80eb24bfc8ff36d7bde0bce976a1ddf 370 PIRSF PIRSF000292 1 298 2.8E-100 T 28-03-2018 IPR006333 Cytochrome o ubiquinol oxidase subunit II GO:0016020|GO:0016682|GO:0055114 CO689_RS05120 0f3e969a5719abd9de94ddf74100069a 115 Pfam PF00420 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L 5 107 1.1E-26 T 28-03-2018 CO689_RS09325 d7d5836c3e68d3806bfe92655f778b6e 335 SUPERFAMILY SSF51735 1 150 4.89E-57 T 28-03-2018 IPR016040 NAD(P)-binding domain CO689_RS09325 d7d5836c3e68d3806bfe92655f778b6e 335 Pfam PF00044 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 3 102 3.6E-35 T 28-03-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CO689_RS09325 d7d5836c3e68d3806bfe92655f778b6e 335 Pfam PF02800 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain 156 313 9.7E-61 T 28-03-2018 IPR020829 Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CO689_RS09325 d7d5836c3e68d3806bfe92655f778b6e 335 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 145 163 2.4E-31 T 28-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CO689_RS09325 d7d5836c3e68d3806bfe92655f778b6e 335 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 266 281 2.4E-31 T 28-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CO689_RS09325 d7d5836c3e68d3806bfe92655f778b6e 335 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 172 188 2.4E-31 T 28-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CO689_RS09325 d7d5836c3e68d3806bfe92655f778b6e 335 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 230 247 2.4E-31 T 28-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CO689_RS09325 d7d5836c3e68d3806bfe92655f778b6e 335 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 109 122 2.4E-31 T 28-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CO689_RS09325 d7d5836c3e68d3806bfe92655f778b6e 335 SUPERFAMILY SSF55347 151 314 2.36E-62 T 28-03-2018 CO689_RS09325 d7d5836c3e68d3806bfe92655f778b6e 335 TIGRFAM TIGR01534 GAPDH-I: glyceraldehyde-3-phosphate dehydrogenase, type I 4 325 8.7E-132 T 28-03-2018 IPR006424 Glyceraldehyde-3-phosphate dehydrogenase, type I GO:0006006|GO:0016620|GO:0050661|GO:0051287|GO:0055114 KEGG: 00010+1.2.1.12|KEGG: 00710+1.2.1.12|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CO689_RS09325 d7d5836c3e68d3806bfe92655f778b6e 335 SMART SM00846 3 151 3.6E-84 T 28-03-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CO689_RS09325 d7d5836c3e68d3806bfe92655f778b6e 335 ProSitePatterns PS00071 Glyceraldehyde 3-phosphate dehydrogenase active site. 149 156 - T 28-03-2018 IPR020830 Glyceraldehyde 3-phosphate dehydrogenase, active site GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CO689_RS09325 d7d5836c3e68d3806bfe92655f778b6e 335 Gene3D G3DSA:3.30.360.10 161 315 2.1E-58 T 28-03-2018 CO689_RS09325 d7d5836c3e68d3806bfe92655f778b6e 335 PIRSF PIRSF000149 1 335 9.9E-116 T 28-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CO689_RS09325 d7d5836c3e68d3806bfe92655f778b6e 335 Gene3D G3DSA:3.40.50.720 1 160 1.1E-71 T 28-03-2018 CO689_RS12775 928cfb969b92fe410506140b7b44beb6 388 ProSitePatterns PS00787 Chorismate synthase signature 1. 7 22 - T 28-03-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 CO689_RS12775 928cfb969b92fe410506140b7b44beb6 388 Pfam PF01264 Chorismate synthase 1 363 2.5E-114 T 28-03-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 CO689_RS12775 928cfb969b92fe410506140b7b44beb6 388 SUPERFAMILY SSF103263 1 384 6.8E-136 T 28-03-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 CO689_RS12775 928cfb969b92fe410506140b7b44beb6 388 ProSitePatterns PS00789 Chorismate synthase signature 3. 337 353 - T 28-03-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 CO689_RS12775 928cfb969b92fe410506140b7b44beb6 388 ProSitePatterns PS00788 Chorismate synthase signature 2. 131 147 - T 28-03-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 CO689_RS12775 928cfb969b92fe410506140b7b44beb6 388 Hamap MF_00300 Chorismate synthase [aroC]. 1 370 33.799 T 28-03-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 CO689_RS12775 928cfb969b92fe410506140b7b44beb6 388 TIGRFAM TIGR00033 aroC: chorismate synthase 1 368 1.6E-121 T 28-03-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 CO689_RS12775 928cfb969b92fe410506140b7b44beb6 388 PIRSF PIRSF001456 1 382 2.2E-119 T 28-03-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 CO689_RS12775 928cfb969b92fe410506140b7b44beb6 388 Gene3D G3DSA:3.60.150.10 1 387 1.3E-128 T 28-03-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 CO689_RS04930 6edc002f3e2efdbae5d108b91d8eede3 459 Gene3D G3DSA:3.40.50.980 3 128 3.5E-15 T 28-03-2018 CO689_RS04930 6edc002f3e2efdbae5d108b91d8eede3 459 Gene3D G3DSA:3.40.50.980 129 277 1.7E-20 T 28-03-2018 CO689_RS04930 6edc002f3e2efdbae5d108b91d8eede3 459 Gene3D G3DSA:3.30.300.30 357 459 1.6E-19 T 28-03-2018 CO689_RS04930 6edc002f3e2efdbae5d108b91d8eede3 459 ProSitePatterns PS00455 Putative AMP-binding domain signature. 125 136 - T 28-03-2018 IPR020845 AMP-binding, conserved site CO689_RS04930 6edc002f3e2efdbae5d108b91d8eede3 459 Gene3D G3DSA:2.30.38.10 278 355 1.3E-9 T 28-03-2018 CO689_RS04930 6edc002f3e2efdbae5d108b91d8eede3 459 Pfam PF00501 AMP-binding enzyme 35 362 1.6E-42 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CO689_RS04930 6edc002f3e2efdbae5d108b91d8eede3 459 Pfam PF13193 AMP-binding enzyme C-terminal domain 371 444 1.7E-7 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CO689_RS04930 6edc002f3e2efdbae5d108b91d8eede3 459 SUPERFAMILY SSF56801 11 454 8.9E-74 T 28-03-2018 CO689_RS11815 fc02bf05a5b2121f865c002e258d6ee5 790 SMART SM00382 464 646 0.005 T 28-03-2018 IPR003593 AAA+ ATPase domain CO689_RS11815 fc02bf05a5b2121f865c002e258d6ee5 790 Gene3D G3DSA:1.10.10.10 723 777 2.5E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS11815 fc02bf05a5b2121f865c002e258d6ee5 790 Pfam PF09397 Ftsk gamma domain 723 783 3.5E-29 T 28-03-2018 IPR018541 FtsK gamma domain CO689_RS11815 fc02bf05a5b2121f865c002e258d6ee5 790 SUPERFAMILY SSF46785 722 787 1.29E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS11815 fc02bf05a5b2121f865c002e258d6ee5 790 SUPERFAMILY SSF52540 404 697 9.96E-46 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CO689_RS11815 fc02bf05a5b2121f865c002e258d6ee5 790 Gene3D G3DSA:3.40.50.300 204 683 3.1E-57 T 28-03-2018 CO689_RS11815 fc02bf05a5b2121f865c002e258d6ee5 790 Pfam PF01580 FtsK/SpoIIIE family 441 625 3.9E-61 T 28-03-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 CO689_RS11815 fc02bf05a5b2121f865c002e258d6ee5 790 SMART SM00843 721 786 3.9E-36 T 28-03-2018 IPR018541 FtsK gamma domain CO689_RS04440 419f94423f4e92aa1254c58ae40a0278 394 Pfam PF12704 MacB-like periplasmic core domain 23 235 3.2E-27 T 28-03-2018 IPR025857 MacB-like periplasmic core domain CO689_RS04440 419f94423f4e92aa1254c58ae40a0278 394 Gene3D G3DSA:1.20.1250.20 4 389 6.5E-4 T 28-03-2018 CO689_RS04440 419f94423f4e92aa1254c58ae40a0278 394 Pfam PF02687 FtsX-like permease family 300 388 1.6E-11 T 28-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 CO689_RS07075 f1dd50c1e6b1eef71274fbb37e386b19 747 Gene3D G3DSA:3.20.20.210 378 742 1.6E-115 T 28-03-2018 CO689_RS07075 f1dd50c1e6b1eef71274fbb37e386b19 747 Gene3D G3DSA:3.20.20.210 3 377 1.3E-115 T 28-03-2018 CO689_RS07075 f1dd50c1e6b1eef71274fbb37e386b19 747 PIRSF PIRSF000382 2 746 0.0 T 28-03-2018 IPR006276 Cobalamin-independent methionine synthase GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 CO689_RS07075 f1dd50c1e6b1eef71274fbb37e386b19 747 SUPERFAMILY SSF51726 385 740 6.41E-108 T 28-03-2018 CO689_RS07075 f1dd50c1e6b1eef71274fbb37e386b19 747 Pfam PF08267 Cobalamin-independent synthase, N-terminal domain 5 308 5.9E-109 T 28-03-2018 IPR013215 Cobalamin-independent methionine synthase MetE, N-terminal GO:0003871|GO:0008270|GO:0008652 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 CO689_RS07075 f1dd50c1e6b1eef71274fbb37e386b19 747 TIGRFAM TIGR01371 met_syn_B12ind: 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase 8 741 0.0 T 28-03-2018 IPR006276 Cobalamin-independent methionine synthase GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 CO689_RS07075 f1dd50c1e6b1eef71274fbb37e386b19 747 Hamap MF_00172 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase [metE]. 3 741 32.512 T 28-03-2018 IPR006276 Cobalamin-independent methionine synthase GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 CO689_RS07075 f1dd50c1e6b1eef71274fbb37e386b19 747 SUPERFAMILY SSF51726 5 371 1.05E-88 T 28-03-2018 CO689_RS07075 f1dd50c1e6b1eef71274fbb37e386b19 747 Pfam PF01717 Cobalamin-independent synthase, Catalytic domain 414 736 1.1E-136 T 28-03-2018 IPR002629 Cobalamin-independent methionine synthase MetE, C-terminal/archaeal GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 CO689_RS05405 6575d6cdbd51717fb5b041f5ab0e4b02 3143 TIGRFAM TIGR01168 YSIRK_signal: gram-positive signal peptide, YSIRK family 64 101 5.0E-14 T 28-03-2018 IPR005877 YSIRK Gram-positive signal peptide GO:0016020 CO689_RS05405 6575d6cdbd51717fb5b041f5ab0e4b02 3143 Pfam PF04650 YSIRK type signal peptide 65 90 8.9E-13 T 28-03-2018 IPR005877 YSIRK Gram-positive signal peptide GO:0016020 CO689_RS05405 6575d6cdbd51717fb5b041f5ab0e4b02 3143 Pfam PF00746 LPXTG cell wall anchor motif 3104 3143 8.6E-9 T 28-03-2018 IPR019948 Gram-positive LPXTG cell wall anchor CO689_RS05405 6575d6cdbd51717fb5b041f5ab0e4b02 3143 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 3110 3143 2.1E-7 T 28-03-2018 CO689_RS13220 e808b0ff89817fbfdaba232bbe3d12fd 207 Pfam PF08279 HTH domain 6 58 4.9E-12 T 28-03-2018 IPR013196 Helix-turn-helix, type 11 CO689_RS13220 e808b0ff89817fbfdaba232bbe3d12fd 207 SMART SM00116 150 202 1.5 T 28-03-2018 IPR000644 CBS domain CO689_RS13220 e808b0ff89817fbfdaba232bbe3d12fd 207 SMART SM00116 83 131 1.8 T 28-03-2018 IPR000644 CBS domain CO689_RS13220 e808b0ff89817fbfdaba232bbe3d12fd 207 Pfam PF00571 CBS domain 84 130 6.0E-5 T 28-03-2018 IPR000644 CBS domain CO689_RS13220 e808b0ff89817fbfdaba232bbe3d12fd 207 Pfam PF00571 CBS domain 144 200 2.6E-4 T 28-03-2018 IPR000644 CBS domain CO689_RS13220 e808b0ff89817fbfdaba232bbe3d12fd 207 SUPERFAMILY SSF46785 2 73 3.4E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS13220 e808b0ff89817fbfdaba232bbe3d12fd 207 Gene3D G3DSA:3.10.580.10 61 206 2.1E-21 T 28-03-2018 CO689_RS13220 e808b0ff89817fbfdaba232bbe3d12fd 207 PIRSF PIRSF026546 1 207 8.0E-97 T 28-03-2018 IPR016842 Protein of unknown function UCP026546, HtH-CBS CO689_RS13220 e808b0ff89817fbfdaba232bbe3d12fd 207 Gene3D G3DSA:1.10.10.10 1 60 1.4E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS13220 e808b0ff89817fbfdaba232bbe3d12fd 207 SUPERFAMILY SSF54631 84 204 7.71E-20 T 28-03-2018 CO689_RS01110 bf78aa972f5125e40dfce350acbdb7e1 153 SUPERFAMILY SSF52121 3 152 3.14E-64 T 28-03-2018 IPR002180 Lumazine/riboflavin synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CO689_RS01110 bf78aa972f5125e40dfce350acbdb7e1 153 TIGRFAM TIGR00114 lumazine-synth: 6,7-dimethyl-8-ribityllumazine synthase 12 148 1.7E-58 T 28-03-2018 IPR034964 Lumazine synthase GO:0000906|GO:0009231 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CO689_RS01110 bf78aa972f5125e40dfce350acbdb7e1 153 Pfam PF00885 6,7-dimethyl-8-ribityllumazine synthase 12 149 3.0E-60 T 28-03-2018 IPR002180 Lumazine/riboflavin synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CO689_RS01110 bf78aa972f5125e40dfce350acbdb7e1 153 Gene3D G3DSA:3.40.50.960 1 153 1.4E-66 T 28-03-2018 IPR002180 Lumazine/riboflavin synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CO689_RS01110 bf78aa972f5125e40dfce350acbdb7e1 153 Hamap MF_00178 6,7-dimethyl-8-ribityllumazine synthase [ribH]. 7 152 31.206 T 28-03-2018 IPR034964 Lumazine synthase GO:0000906|GO:0009231 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CO689_RS13365 0dfec86c0c5d6b91ee9447949b6f04ad 190 Gene3D G3DSA:3.40.50.620 1 190 2.4E-43 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CO689_RS13365 0dfec86c0c5d6b91ee9447949b6f04ad 190 TIGRFAM TIGR00482 TIGR00482: nicotinate (nicotinamide) nucleotide adenylyltransferase 7 188 1.7E-56 T 28-03-2018 IPR005248 Nicotinate/nicotinamide nucleotide adenylyltransferase GO:0009435|GO:0016779 KEGG: 00760+2.7.7.18|MetaCyc: PWY-5381|MetaCyc: PWY-5653|MetaCyc: PWY-7761|Reactome: R-HSA-196807 CO689_RS13365 0dfec86c0c5d6b91ee9447949b6f04ad 190 Hamap MF_00244 Probable nicotinate-nucleotide adenylyltransferase [nadD]. 3 189 28.303 T 28-03-2018 IPR005248 Nicotinate/nicotinamide nucleotide adenylyltransferase GO:0009435|GO:0016779 KEGG: 00760+2.7.7.18|MetaCyc: PWY-5381|MetaCyc: PWY-5653|MetaCyc: PWY-7761|Reactome: R-HSA-196807 CO689_RS13365 0dfec86c0c5d6b91ee9447949b6f04ad 190 Pfam PF01467 Cytidylyltransferase-like 7 163 6.5E-26 T 28-03-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 CO689_RS13365 0dfec86c0c5d6b91ee9447949b6f04ad 190 SUPERFAMILY SSF52374 3 188 1.94E-43 T 28-03-2018 CO689_RS10105 09691fe1865eb29e62080073b9955eaf 1219 Gene3D G3DSA:3.40.50.300 4 179 1.1E-26 T 28-03-2018 CO689_RS10105 09691fe1865eb29e62080073b9955eaf 1219 Gene3D G3DSA:3.40.50.300 227 464 1.6E-28 T 28-03-2018 CO689_RS10105 09691fe1865eb29e62080073b9955eaf 1219 Gene3D G3DSA:3.40.50.300 467 877 3.3E-45 T 28-03-2018 CO689_RS10105 09691fe1865eb29e62080073b9955eaf 1219 Gene3D G3DSA:3.90.320.10 986 1214 2.2E-34 T 28-03-2018 IPR011604 Exonuclease, phage-type/RecB, C-terminal GO:0003677|GO:0004518 CO689_RS10105 09691fe1865eb29e62080073b9955eaf 1219 Hamap MF_01451 ATP-dependent helicase/nuclease subunit A [addA]. 8 1216 17.822 T 28-03-2018 IPR014152 DNA helicase subunit AddA GO:0004003|GO:0006302 CO689_RS10105 09691fe1865eb29e62080073b9955eaf 1219 Pfam PF13361 UvrD-like helicase C-terminal domain 464 865 3.8E-30 T 28-03-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 CO689_RS10105 09691fe1865eb29e62080073b9955eaf 1219 TIGRFAM TIGR02785 addA_Gpos: helicase-exonuclease AddAB, AddA subunit 11 1210 0.0 T 28-03-2018 IPR014152 DNA helicase subunit AddA GO:0004003|GO:0006302 CO689_RS10105 09691fe1865eb29e62080073b9955eaf 1219 SUPERFAMILY SSF52540 339 802 7.46E-113 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CO689_RS10105 09691fe1865eb29e62080073b9955eaf 1219 SUPERFAMILY SSF52540 10 178 7.46E-113 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CO689_RS10105 09691fe1865eb29e62080073b9955eaf 1219 SUPERFAMILY SSF52540 844 870 7.46E-113 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CO689_RS10105 09691fe1865eb29e62080073b9955eaf 1219 SUPERFAMILY SSF52980 994 1210 3.81E-37 T 28-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 CO689_RS10105 09691fe1865eb29e62080073b9955eaf 1219 Pfam PF00580 UvrD/REP helicase N-terminal domain 11 454 1.1E-77 T 28-03-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 CO689_RS10105 09691fe1865eb29e62080073b9955eaf 1219 Pfam PF12705 PD-(D/E)XK nuclease superfamily 1034 1209 1.0E-11 T 28-03-2018 CO689_RS08930 daaa452b2d6afbd2d026333e7b29214a 648 SUPERFAMILY SSF53649 247 639 9.72E-68 T 28-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 CO689_RS08930 daaa452b2d6afbd2d026333e7b29214a 648 PIRSF PIRSF005091 1 626 2.2E-179 T 28-03-2018 IPR012160 Lipoteichoic acid synthase-like CO689_RS08930 daaa452b2d6afbd2d026333e7b29214a 648 Pfam PF00884 Sulfatase 249 540 1.9E-29 T 28-03-2018 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 CO689_RS08930 daaa452b2d6afbd2d026333e7b29214a 648 Gene3D G3DSA:3.40.720.10 241 551 4.6E-35 T 28-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 CO689_RS11520 39df32842ab15d325ad063aada2c555b 328 Pfam PF02504 Fatty acid synthesis protein 2 315 5.1E-111 T 28-03-2018 IPR003664 Fatty acid synthesis PlsX protein GO:0003824|GO:0006633|GO:0016747 CO689_RS11520 39df32842ab15d325ad063aada2c555b 328 TIGRFAM TIGR00182 plsX: fatty acid/phospholipid synthesis protein PlsX 4 324 3.0E-118 T 28-03-2018 IPR012281 Phospholipid biosynthesis protein, PlsX-like GO:0006633 CO689_RS11520 39df32842ab15d325ad063aada2c555b 328 SUPERFAMILY SSF53659 1 324 4.52E-101 T 28-03-2018 CO689_RS11520 39df32842ab15d325ad063aada2c555b 328 Hamap MF_00019 Phosphate acyltransferase [plsX]. 1 328 142.796 T 28-03-2018 IPR012281 Phospholipid biosynthesis protein, PlsX-like GO:0006633 CO689_RS11520 39df32842ab15d325ad063aada2c555b 328 PIRSF PIRSF002465 1 328 3.4E-126 T 28-03-2018 IPR012281 Phospholipid biosynthesis protein, PlsX-like GO:0006633 CO689_RS11520 39df32842ab15d325ad063aada2c555b 328 Gene3D G3DSA:3.40.718.10 1 328 1.2E-102 T 28-03-2018 CO689_RS05055 c251656eb9217bc72ddb41f8097bdd11 192 TIGRFAM TIGR02365 dha_L_ycgS: dihydroxyacetone kinase, L subunit 7 189 7.8E-67 T 28-03-2018 IPR012737 Dihydroxyacetone kinase, subunit L GO:0016772 CO689_RS05055 c251656eb9217bc72ddb41f8097bdd11 192 Pfam PF02734 DAK2 domain 30 188 1.2E-41 T 28-03-2018 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 CO689_RS05055 c251656eb9217bc72ddb41f8097bdd11 192 SMART SM01120 30 190 4.5E-53 T 28-03-2018 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 CO689_RS05055 c251656eb9217bc72ddb41f8097bdd11 192 SUPERFAMILY SSF101473 2 189 5.49E-49 T 28-03-2018 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 CO689_RS05245 80256aa8434f3b73fdeccff3fe582e73 397 Gene3D G3DSA:2.60.120.580 3 150 1.8E-30 T 28-03-2018 CO689_RS05245 80256aa8434f3b73fdeccff3fe582e73 397 Gene3D G3DSA:2.60.120.580 151 282 4.3E-34 T 28-03-2018 CO689_RS05245 80256aa8434f3b73fdeccff3fe582e73 397 Gene3D G3DSA:3.10.28.20 298 386 1.8E-15 T 28-03-2018 CO689_RS05245 80256aa8434f3b73fdeccff3fe582e73 397 SUPERFAMILY SSF141130 20 165 1.7E-76 T 28-03-2018 CO689_RS05245 80256aa8434f3b73fdeccff3fe582e73 397 SUPERFAMILY SSF141130 214 385 1.7E-76 T 28-03-2018 CO689_RS05245 80256aa8434f3b73fdeccff3fe582e73 397 Pfam PF03069 Acetamidase/Formamidase family 8 386 3.5E-171 T 28-03-2018 IPR004304 Acetamidase/Formamidase GO:0016811 CO689_RS10375 3257cfcee4e48692677fc3f4268a4a75 193 SUPERFAMILY SSF54211 88 176 3.49E-32 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CO689_RS10375 3257cfcee4e48692677fc3f4268a4a75 193 ProSitePatterns PS00954 Imidazoleglycerol-phosphate dehydratase signature 1. 60 73 - T 28-03-2018 IPR020565 Imidazoleglycerol-phosphate dehydratase, conserved site GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 CO689_RS10375 3257cfcee4e48692677fc3f4268a4a75 193 Hamap MF_00076 Imidazoleglycerol-phosphate dehydratase [hisB]. 1 192 37.276 T 28-03-2018 IPR000807 Imidazoleglycerol-phosphate dehydratase GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 CO689_RS10375 3257cfcee4e48692677fc3f4268a4a75 193 Pfam PF00475 Imidazoleglycerol-phosphate dehydratase 30 173 2.3E-60 T 28-03-2018 IPR000807 Imidazoleglycerol-phosphate dehydratase GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 CO689_RS10375 3257cfcee4e48692677fc3f4268a4a75 193 Gene3D G3DSA:3.30.230.40 1 87 4.2E-27 T 28-03-2018 CO689_RS10375 3257cfcee4e48692677fc3f4268a4a75 193 Gene3D G3DSA:3.30.230.40 89 193 2.1E-28 T 28-03-2018 CO689_RS10375 3257cfcee4e48692677fc3f4268a4a75 193 SUPERFAMILY SSF54211 3 84 9.23E-27 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CO689_RS10375 3257cfcee4e48692677fc3f4268a4a75 193 ProSitePatterns PS00955 Imidazoleglycerol-phosphate dehydratase signature 2. 155 167 - T 28-03-2018 IPR020565 Imidazoleglycerol-phosphate dehydratase, conserved site GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 CO689_RS12870 91a28ae20556a4883b697ca6b1c87fb5 244 Gene3D G3DSA:3.30.2350.10 75 244 6.7E-42 T 28-03-2018 CO689_RS12870 91a28ae20556a4883b697ca6b1c87fb5 244 SUPERFAMILY SSF55120 65 234 6.96E-44 T 28-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 CO689_RS12870 91a28ae20556a4883b697ca6b1c87fb5 244 TIGRFAM TIGR00093 TIGR00093: pseudouridine synthase 70 230 2.4E-50 T 28-03-2018 IPR000748 Pseudouridine synthase, RsuA/RluB/E/F GO:0001522|GO:0003723|GO:0009451|GO:0016866 CO689_RS12870 91a28ae20556a4883b697ca6b1c87fb5 244 SUPERFAMILY SSF55174 6 71 4.12E-15 T 28-03-2018 CO689_RS12870 91a28ae20556a4883b697ca6b1c87fb5 244 Pfam PF00849 RNA pseudouridylate synthase 66 200 2.7E-23 T 28-03-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 CO689_RS12870 91a28ae20556a4883b697ca6b1c87fb5 244 SMART SM00363 6 63 3.3E-13 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CO689_RS12870 91a28ae20556a4883b697ca6b1c87fb5 244 Gene3D G3DSA:3.10.290.10 1 74 5.0E-19 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CO689_RS12870 91a28ae20556a4883b697ca6b1c87fb5 244 Pfam PF01479 S4 domain 6 52 1.6E-13 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CO689_RS12870 91a28ae20556a4883b697ca6b1c87fb5 244 ProSitePatterns PS01149 Rsu family of pseudouridine synthase signature. 103 117 - T 28-03-2018 IPR018496 Pseudouridine synthase, RsuA/RluB/E/F, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0016866 CO689_RS07760 cb8abad4f8eb1052e18ac0753d171037 136 Gene3D G3DSA:2.40.50.140 1 80 4.6E-27 T 28-03-2018 CO689_RS07760 cb8abad4f8eb1052e18ac0753d171037 136 SMART SM00316 4 74 3.3E-26 T 28-03-2018 IPR022967 RNA-binding domain, S1 CO689_RS07760 cb8abad4f8eb1052e18ac0753d171037 136 Pfam PF00575 S1 RNA binding domain 4 74 3.3E-21 T 28-03-2018 IPR003029 S1 domain GO:0003676 CO689_RS07760 cb8abad4f8eb1052e18ac0753d171037 136 SUPERFAMILY SSF50249 4 82 7.26E-24 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CO689_RS06540 3c0b5f8ee6ec08cdc485288c8715f65d 169 Pfam PF07274 Protein of unknown function (DUF1440) 21 155 1.6E-56 T 28-03-2018 IPR009898 Protein of unknown function DUF1440 CO689_RS11800 5aa82a5402fff6e1b556896dcac76f06 89 Pfam PF00312 Ribosomal protein S15 8 88 4.9E-38 T 28-03-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CO689_RS11800 5aa82a5402fff6e1b556896dcac76f06 89 TIGRFAM TIGR00952 S15_bact: ribosomal protein uS15 5 89 1.9E-40 T 28-03-2018 IPR005290 Ribosomal protein S15, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CO689_RS11800 5aa82a5402fff6e1b556896dcac76f06 89 ProDom PD157043 RIBOSOMAL S15 RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 30S CHLOROPLAST S15 MITOCHONDRIAL TYPE 10 88 9.0E-38 T 28-03-2018 CO689_RS11800 5aa82a5402fff6e1b556896dcac76f06 89 ProSitePatterns PS00362 Ribosomal protein S15 signature. 39 69 - T 28-03-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CO689_RS11800 5aa82a5402fff6e1b556896dcac76f06 89 SUPERFAMILY SSF47060 3 89 3.83E-37 T 28-03-2018 IPR009068 S15/NS1, RNA-binding CO689_RS11800 5aa82a5402fff6e1b556896dcac76f06 89 Gene3D G3DSA:1.10.287.10 2 89 4.0E-36 T 28-03-2018 CO689_RS11800 5aa82a5402fff6e1b556896dcac76f06 89 Hamap MF_01343_B 30S ribosomal protein S15 [rpsO]. 3 89 23.227 T 28-03-2018 IPR005290 Ribosomal protein S15, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CO689_RS11800 5aa82a5402fff6e1b556896dcac76f06 89 SMART SM01387 8 88 1.1E-51 T 28-03-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CO689_RS06205 1105fb2c165109e4d206a20047be5018 280 Pfam PF13248 zinc-ribbon domain 2 24 1.1E-6 T 28-03-2018 CO689_RS06205 1105fb2c165109e4d206a20047be5018 280 Gene3D G3DSA:2.20.28.20 2 28 5.6E-6 T 28-03-2018 CO689_RS04735 6e2ce82d83ae2f0de4a60d991b8a9798 215 TIGRFAM TIGR01182 eda: 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase 8 201 5.4E-51 T 28-03-2018 IPR000887 KDPG/KHG aldolase GO:0008152|GO:0016829 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 CO689_RS04735 6e2ce82d83ae2f0de4a60d991b8a9798 215 Gene3D G3DSA:3.20.20.70 4 211 2.7E-32 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CO689_RS04735 6e2ce82d83ae2f0de4a60d991b8a9798 215 SUPERFAMILY SSF51569 2 205 2.93E-58 T 28-03-2018 CO689_RS04735 6e2ce82d83ae2f0de4a60d991b8a9798 215 Pfam PF01081 KDPG and KHG aldolase 8 185 2.6E-40 T 28-03-2018 IPR000887 KDPG/KHG aldolase GO:0008152|GO:0016829 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 CO689_RS06720 10c896b56bfeb37e8037d2d9dc6ae0e9 105 Pfam PF01022 Bacterial regulatory protein, arsR family 15 60 3.7E-16 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CO689_RS06720 10c896b56bfeb37e8037d2d9dc6ae0e9 105 Gene3D G3DSA:1.10.10.10 1 86 1.8E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS06720 10c896b56bfeb37e8037d2d9dc6ae0e9 105 SUPERFAMILY SSF46785 3 84 1.41E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS06720 10c896b56bfeb37e8037d2d9dc6ae0e9 105 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 10 25 1.3E-18 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CO689_RS06720 10c896b56bfeb37e8037d2d9dc6ae0e9 105 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 29 40 1.3E-18 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CO689_RS06720 10c896b56bfeb37e8037d2d9dc6ae0e9 105 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 57 72 1.3E-18 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CO689_RS06720 10c896b56bfeb37e8037d2d9dc6ae0e9 105 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 42 57 1.3E-18 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CO689_RS06720 10c896b56bfeb37e8037d2d9dc6ae0e9 105 ProSitePatterns PS00846 Bacterial regulatory proteins, arsR family signature. 31 49 - T 28-03-2018 IPR018334 ArsR-type transcription regulator, HTH motif GO:0003700|GO:0005622|GO:0006355 CO689_RS06720 10c896b56bfeb37e8037d2d9dc6ae0e9 105 SMART SM00418 8 85 2.6E-26 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CO689_RS05950 942ac7182679bea0d148e0676625e846 308 Gene3D G3DSA:3.10.180.10 2 147 8.5E-19 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CO689_RS05950 942ac7182679bea0d148e0676625e846 308 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 7 126 8.4E-11 T 28-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CO689_RS05950 942ac7182679bea0d148e0676625e846 308 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 160 274 6.7E-7 T 28-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CO689_RS05950 942ac7182679bea0d148e0676625e846 308 SUPERFAMILY SSF54593 3 296 2.36E-44 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CO689_RS05950 942ac7182679bea0d148e0676625e846 308 Gene3D G3DSA:3.10.180.10 150 308 1.5E-18 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CO689_RS06260 1bd8227239e97e8c893460633610a637 463 SUPERFAMILY SSF53383 95 459 4.44E-62 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CO689_RS06260 1bd8227239e97e8c893460633610a637 463 Pfam PF00392 Bacterial regulatory proteins, gntR family 9 71 1.8E-13 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CO689_RS06260 1bd8227239e97e8c893460633610a637 463 Gene3D G3DSA:3.40.640.10 121 361 3.0E-25 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CO689_RS06260 1bd8227239e97e8c893460633610a637 463 SUPERFAMILY SSF46785 8 79 2.32E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS06260 1bd8227239e97e8c893460633610a637 463 Pfam PF00155 Aminotransferase class I and II 115 402 1.2E-17 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CO689_RS06260 1bd8227239e97e8c893460633610a637 463 Gene3D G3DSA:1.10.10.10 2 73 9.4E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS06260 1bd8227239e97e8c893460633610a637 463 Gene3D G3DSA:3.90.1150.10 362 461 1.0E-9 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CO689_RS06260 1bd8227239e97e8c893460633610a637 463 SMART SM00345 12 71 1.2E-13 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CO689_RS05790 469adf8858874ef9df40af6448dd8cd8 495 TIGRFAM TIGR01320 mal_quin_oxido: malate dehydrogenase (acceptor) 8 490 1.5E-183 T 28-03-2018 IPR006231 Malate:quinone-oxidoreductase GO:0006099|GO:0008924 KEGG: 00020+1.1.5.4|KEGG: 00620+1.1.5.4|MetaCyc: PWY-7254 CO689_RS05790 469adf8858874ef9df40af6448dd8cd8 495 Hamap MF_00212 Probable malate:quinone oxidoreductase [mqo]. 3 492 49.95 T 28-03-2018 IPR006231 Malate:quinone-oxidoreductase GO:0006099|GO:0008924 KEGG: 00020+1.1.5.4|KEGG: 00620+1.1.5.4|MetaCyc: PWY-7254 CO689_RS05790 469adf8858874ef9df40af6448dd8cd8 495 Pfam PF06039 Malate:quinone oxidoreductase (Mqo) 6 492 8.8E-216 T 28-03-2018 IPR006231 Malate:quinone-oxidoreductase GO:0006099|GO:0008924 KEGG: 00020+1.1.5.4|KEGG: 00620+1.1.5.4|MetaCyc: PWY-7254 CO689_RS05790 469adf8858874ef9df40af6448dd8cd8 495 SUPERFAMILY SSF51905 5 274 1.69E-17 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CO689_RS05790 469adf8858874ef9df40af6448dd8cd8 495 Gene3D G3DSA:3.50.50.60 1 427 5.8E-13 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CO689_RS12410 a066f017c4f847b9d083e34814fba04e 215 TIGRFAM TIGR02135 phoU_full: phosphate transport system regulatory protein PhoU 6 210 1.8E-65 T 28-03-2018 IPR028366 Phosphate transport system protein PhoU GO:0005737|GO:0030643|GO:0045936 CO689_RS12410 a066f017c4f847b9d083e34814fba04e 215 SUPERFAMILY SSF109755 5 212 1.99E-53 T 28-03-2018 CO689_RS12410 a066f017c4f847b9d083e34814fba04e 215 Gene3D G3DSA:1.20.58.220 114 214 2.5E-20 T 28-03-2018 CO689_RS12410 a066f017c4f847b9d083e34814fba04e 215 Gene3D G3DSA:1.20.58.220 1 113 2.4E-21 T 28-03-2018 CO689_RS12410 a066f017c4f847b9d083e34814fba04e 215 Pfam PF01895 PhoU domain 26 106 1.3E-17 T 28-03-2018 IPR026022 PhoU domain CO689_RS12410 a066f017c4f847b9d083e34814fba04e 215 Pfam PF01895 PhoU domain 121 201 2.6E-18 T 28-03-2018 IPR026022 PhoU domain CO689_RS12410 a066f017c4f847b9d083e34814fba04e 215 PIRSF PIRSF003107 1 214 2.2E-65 T 28-03-2018 IPR028366 Phosphate transport system protein PhoU GO:0005737|GO:0030643|GO:0045936 CO689_RS08285 b26874b0150c426aabe50d697c6606ef 329 PIRSF PIRSF000428 1 329 2.1E-109 T 28-03-2018 IPR012147 Phosphate acetyl/butyryltransferase GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 CO689_RS08285 b26874b0150c426aabe50d697c6606ef 329 TIGRFAM TIGR00651 pta: phosphate acetyltransferase 19 324 1.4E-117 T 28-03-2018 IPR004614 Phosphate acetyltransferase GO:0016407 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 CO689_RS08285 b26874b0150c426aabe50d697c6606ef 329 SUPERFAMILY SSF53659 5 327 3.95E-89 T 28-03-2018 CO689_RS08285 b26874b0150c426aabe50d697c6606ef 329 Pfam PF01515 Phosphate acetyl/butaryl transferase 5 324 1.2E-119 T 28-03-2018 IPR002505 Phosphate acetyl/butaryl transferase GO:0008152|GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 CO689_RS08285 b26874b0150c426aabe50d697c6606ef 329 Gene3D G3DSA:3.40.50.10750 142 300 1.6E-62 T 28-03-2018 CO689_RS12555 ee3328a9dd842e9b2a8972dc56e3725b 931 Gene3D G3DSA:3.40.50.970 145 521 5.0E-77 T 28-03-2018 CO689_RS12555 ee3328a9dd842e9b2a8972dc56e3725b 931 Gene3D G3DSA:1.10.287.1150 62 143 3.5E-10 T 28-03-2018 CO689_RS12555 ee3328a9dd842e9b2a8972dc56e3725b 931 TIGRFAM TIGR00239 2oxo_dh_E1: oxoglutarate dehydrogenase (succinyl-transferring), E1 component 15 926 0.0 T 28-03-2018 IPR011603 2-oxoglutarate dehydrogenase E1 component GO:0004591|GO:0006099|GO:0030976|GO:0055114 KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 CO689_RS12555 ee3328a9dd842e9b2a8972dc56e3725b 931 Pfam PF16870 2-oxoglutarate dehydrogenase C-terminal 791 927 1.9E-35 T 28-03-2018 IPR031717 Multifunctional 2-oxoglutarate metabolism enzyme, C-terminal KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 CO689_RS12555 ee3328a9dd842e9b2a8972dc56e3725b 931 PIRSF PIRSF000157 1 930 0.0 T 28-03-2018 IPR011603 2-oxoglutarate dehydrogenase E1 component GO:0004591|GO:0006099|GO:0030976|GO:0055114 KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 CO689_RS12555 ee3328a9dd842e9b2a8972dc56e3725b 931 SUPERFAMILY SSF52518 573 790 1.18E-39 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CO689_RS12555 ee3328a9dd842e9b2a8972dc56e3725b 931 Hamap MF_01169 2-oxoglutarate dehydrogenase E1 component [odhA]. 1 930 21.418 T 28-03-2018 IPR023784 2-oxoglutarate dehydrogenase E1 component, bacterial KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 CO689_RS12555 ee3328a9dd842e9b2a8972dc56e3725b 931 Gene3D G3DSA:3.40.50.970 585 798 1.0E-47 T 28-03-2018 CO689_RS12555 ee3328a9dd842e9b2a8972dc56e3725b 931 SUPERFAMILY SSF52518 133 528 2.02E-69 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CO689_RS12555 ee3328a9dd842e9b2a8972dc56e3725b 931 SMART SM00861 588 784 1.1E-42 T 28-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain CO689_RS12555 ee3328a9dd842e9b2a8972dc56e3725b 931 Pfam PF02779 Transketolase, pyrimidine binding domain 588 784 1.2E-53 T 28-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain CO689_RS12555 ee3328a9dd842e9b2a8972dc56e3725b 931 Pfam PF00676 Dehydrogenase E1 component 211 522 6.6E-59 T 28-03-2018 IPR001017 Dehydrogenase, E1 component GO:0008152|GO:0016624 Reactome: R-HSA-389661 CO689_RS11390 583ce744eaec19211146b1fd9757f895 572 Gene3D G3DSA:1.10.8.50 166 235 9.3E-18 T 28-03-2018 CO689_RS11390 583ce744eaec19211146b1fd9757f895 572 Pfam PF05670 Domain of unknown function (DUF814) 449 533 3.5E-28 T 28-03-2018 IPR008532 Domain of unknown function DUF814 CO689_RS11390 583ce744eaec19211146b1fd9757f895 572 Pfam PF05833 Fibronectin-binding protein A N-terminus (FbpA) 4 440 9.6E-143 T 28-03-2018 CO689_RS11390 583ce744eaec19211146b1fd9757f895 572 Gene3D G3DSA:3.40.970.40 238 288 7.4E-11 T 28-03-2018 CO689_RS11390 583ce744eaec19211146b1fd9757f895 572 Gene3D G3DSA:2.30.310.10 1 165 3.0E-47 T 28-03-2018 CO689_RS03115 3eee8db92ad3c3d57c61a2f7a4ed257c 144 TIGRFAM TIGR01164 rplP_bact: ribosomal protein uL16 2 127 9.6E-61 T 28-03-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CO689_RS03115 3eee8db92ad3c3d57c61a2f7a4ed257c 144 PRINTS PR00060 Ribosomal protein L16 signature 88 117 5.4E-40 T 28-03-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CO689_RS03115 3eee8db92ad3c3d57c61a2f7a4ed257c 144 PRINTS PR00060 Ribosomal protein L16 signature 24 36 5.4E-40 T 28-03-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CO689_RS03115 3eee8db92ad3c3d57c61a2f7a4ed257c 144 PRINTS PR00060 Ribosomal protein L16 signature 58 87 5.4E-40 T 28-03-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CO689_RS03115 3eee8db92ad3c3d57c61a2f7a4ed257c 144 PRINTS PR00060 Ribosomal protein L16 signature 42 53 5.4E-40 T 28-03-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CO689_RS03115 3eee8db92ad3c3d57c61a2f7a4ed257c 144 ProSitePatterns PS00701 Ribosomal protein L16 signature 2. 82 93 - T 28-03-2018 IPR020798 Ribosomal protein L16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CO689_RS03115 3eee8db92ad3c3d57c61a2f7a4ed257c 144 Gene3D G3DSA:3.90.1170.10 3 139 1.9E-52 T 28-03-2018 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 CO689_RS03115 3eee8db92ad3c3d57c61a2f7a4ed257c 144 Hamap MF_01342 50S ribosomal protein L16 [rplP]. 1 134 39.89 T 28-03-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CO689_RS03115 3eee8db92ad3c3d57c61a2f7a4ed257c 144 SUPERFAMILY SSF54686 1 137 9.29E-58 T 28-03-2018 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 CO689_RS03115 3eee8db92ad3c3d57c61a2f7a4ed257c 144 ProSitePatterns PS00586 Ribosomal protein L16 signature 1. 59 70 - T 28-03-2018 IPR020798 Ribosomal protein L16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CO689_RS03115 3eee8db92ad3c3d57c61a2f7a4ed257c 144 Pfam PF00252 Ribosomal protein L16p/L10e 4 132 3.0E-51 T 28-03-2018 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 CO689_RS13255 9652a75c20b2bbb1286649585d235459 315 SUPERFAMILY SSF52540 60 288 1.15E-37 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CO689_RS13255 9652a75c20b2bbb1286649585d235459 315 SUPERFAMILY SSF54791 8 64 2.28E-5 T 28-03-2018 IPR004088 K Homology domain, type 1 GO:0003723 CO689_RS13255 9652a75c20b2bbb1286649585d235459 315 Pfam PF02562 PhoH-like protein 109 312 1.1E-92 T 28-03-2018 IPR003714 PhoH-like protein GO:0005524 CO689_RS13255 9652a75c20b2bbb1286649585d235459 315 Gene3D G3DSA:3.40.50.300 106 312 2.8E-29 T 28-03-2018 CO689_RS11550 7f4ed5faf39e04ac23b97eb07b3c92a2 411 SMART SM00963 83 164 1.1E-22 T 28-03-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CO689_RS11550 7f4ed5faf39e04ac23b97eb07b3c92a2 411 TIGRFAM TIGR00064 ftsY: signal recognition particle-docking protein FtsY 108 381 6.8E-118 T 28-03-2018 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 CO689_RS11550 7f4ed5faf39e04ac23b97eb07b3c92a2 411 Pfam PF02881 SRP54-type protein, helical bundle domain 95 159 3.8E-13 T 28-03-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CO689_RS11550 7f4ed5faf39e04ac23b97eb07b3c92a2 411 SMART SM00382 180 360 1.2E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain CO689_RS11550 7f4ed5faf39e04ac23b97eb07b3c92a2 411 ProSitePatterns PS00300 SRP54-type proteins GTP-binding domain signature. 355 368 - T 28-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CO689_RS11550 7f4ed5faf39e04ac23b97eb07b3c92a2 411 Hamap MF_00920 Signal recognition particle receptor FtsY [ftsY]. 107 382 64.108 T 28-03-2018 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 CO689_RS11550 7f4ed5faf39e04ac23b97eb07b3c92a2 411 Gene3D G3DSA:3.40.50.300 174 383 9.5E-44 T 28-03-2018 CO689_RS11550 7f4ed5faf39e04ac23b97eb07b3c92a2 411 SMART SM00962 181 382 1.9E-123 T 28-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CO689_RS11550 7f4ed5faf39e04ac23b97eb07b3c92a2 411 Pfam PF00448 SRP54-type protein, GTPase domain 182 381 1.2E-81 T 28-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CO689_RS11550 7f4ed5faf39e04ac23b97eb07b3c92a2 411 Gene3D G3DSA:1.20.120.140 4 166 1.0E-22 T 28-03-2018 CO689_RS11550 7f4ed5faf39e04ac23b97eb07b3c92a2 411 SUPERFAMILY SSF47364 81 158 9.03E-20 T 28-03-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CO689_RS11550 7f4ed5faf39e04ac23b97eb07b3c92a2 411 SUPERFAMILY SSF52540 135 395 2.9E-52 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CO689_RS13175 914111a209a433bcf205876b4a96b504 282 SUPERFAMILY SSF81345 4 267 4.05E-35 T 28-03-2018 IPR029022 ABC transporter, BtuC-like CO689_RS13175 914111a209a433bcf205876b4a96b504 282 Pfam PF00950 ABC 3 transport family 8 270 8.5E-61 T 28-03-2018 IPR001626 ABC transporter, TroCD-like GO:0005887|GO:0042626|GO:0043190|GO:0055085 CO689_RS13175 914111a209a433bcf205876b4a96b504 282 Gene3D G3DSA:1.10.3470.10 2 278 7.2E-24 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CO689_RS09505 9cf4b181da4b3005f1799f625fedd02e 435 SUPERFAMILY SSF101960 14 433 3.01E-113 T 28-03-2018 CO689_RS09505 9cf4b181da4b3005f1799f625fedd02e 435 Pfam PF01458 Uncharacterized protein family (UPF0051) 183 408 1.9E-58 T 28-03-2018 IPR000825 SUF system FeS cluster assembly, SufBD GO:0016226 CO689_RS09505 9cf4b181da4b3005f1799f625fedd02e 435 TIGRFAM TIGR01981 sufD: FeS assembly protein SufD 150 424 2.4E-73 T 28-03-2018 IPR011542 SUF system FeS cluster assembly, SufD GO:0016226 CO689_RS12710 cd8b2fba0e7a95d8065a13da78963e92 225 Pfam PF07261 Replication initiation and membrane attachment 126 196 2.4E-23 T 28-03-2018 IPR006343 DnaD domain CO689_RS12710 cd8b2fba0e7a95d8065a13da78963e92 225 SUPERFAMILY SSF158499 125 191 3.53E-20 T 28-03-2018 IPR006343 DnaD domain CO689_RS12710 cd8b2fba0e7a95d8065a13da78963e92 225 Gene3D G3DSA:1.10.10.10 3 79 0.024 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS12710 cd8b2fba0e7a95d8065a13da78963e92 225 TIGRFAM TIGR01446 DnaD_dom: DnaD domain protein 125 195 2.5E-24 T 28-03-2018 IPR006343 DnaD domain CO689_RS12710 cd8b2fba0e7a95d8065a13da78963e92 225 Gene3D G3DSA:1.10.10.630 120 197 6.7E-25 T 28-03-2018 IPR034829 DnaD-like domain CO689_RS04590 fc6359d5f2553f7556b37938a38e5aab 232 Gene3D G3DSA:3.30.1890.10 39 150 7.2E-4 T 28-03-2018 CO689_RS04590 fc6359d5f2553f7556b37938a38e5aab 232 Pfam PF02706 Chain length determinant protein 5 94 2.0E-14 T 28-03-2018 IPR003856 Polysaccharide chain length determinant N-terminal domain GO:0009103|GO:0016020 CO689_RS08895 3da5a5632ad3a4590da7146816c34c8d 223 PIRSF PIRSF006293 7 223 5.0E-79 T 28-03-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 CO689_RS08895 3da5a5632ad3a4590da7146816c34c8d 223 Gene3D G3DSA:3.40.50.620 8 223 3.4E-53 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CO689_RS08895 3da5a5632ad3a4590da7146816c34c8d 223 Pfam PF06508 Queuosine biosynthesis protein QueC 10 216 2.5E-85 T 28-03-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 CO689_RS08895 3da5a5632ad3a4590da7146816c34c8d 223 SUPERFAMILY SSF52402 8 219 2.21E-64 T 28-03-2018 CO689_RS08895 3da5a5632ad3a4590da7146816c34c8d 223 Hamap MF_01633 7-cyano-7-deazaguanine synthase [queC]. 9 222 50.558 T 28-03-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 CO689_RS08895 3da5a5632ad3a4590da7146816c34c8d 223 TIGRFAM TIGR00364 TIGR00364: queuosine biosynthesis protein QueC 11 209 3.5E-82 T 28-03-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 CO689_RS10855 47c84a1eb34c1019474f41aace1fcd6c 210 Pfam PF10368 Putative cell-wall binding lipoprotein 12 195 5.8E-38 T 28-03-2018 IPR019454 Putative cell-wall binding lipoprotein YkyA-like CO689_RS10855 47c84a1eb34c1019474f41aace1fcd6c 210 Gene3D G3DSA:1.20.120.570 10 210 2.1E-35 T 28-03-2018 CO689_RS10855 47c84a1eb34c1019474f41aace1fcd6c 210 SUPERFAMILY SSF140423 22 202 3.01E-33 T 28-03-2018 IPR019454 Putative cell-wall binding lipoprotein YkyA-like CO689_RS03635 0eaba0cef6e003f16048ab732e6efd96 562 Pfam PF01175 Urocanase Rossmann-like domain 141 349 2.3E-89 T 28-03-2018 IPR035085 Urocanase, Rossmann-like domain KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 CO689_RS03635 0eaba0cef6e003f16048ab732e6efd96 562 Hamap MF_00577 Urocanate hydratase [hutU]. 2 556 50.522 T 28-03-2018 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 CO689_RS03635 0eaba0cef6e003f16048ab732e6efd96 562 ProSitePatterns PS01233 Urocanase signature. 442 457 - T 28-03-2018 IPR023636 Urocanase conserved site GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 CO689_RS03635 0eaba0cef6e003f16048ab732e6efd96 562 SUPERFAMILY SSF111326 9 556 4.32E-256 T 28-03-2018 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 CO689_RS03635 0eaba0cef6e003f16048ab732e6efd96 562 Gene3D G3DSA:3.40.1770.10 10 153 1.2E-27 T 28-03-2018 CO689_RS03635 0eaba0cef6e003f16048ab732e6efd96 562 Gene3D G3DSA:3.40.1770.10 196 555 2.9E-159 T 28-03-2018 CO689_RS03635 0eaba0cef6e003f16048ab732e6efd96 562 Pfam PF17392 Urocanase C-terminal domain 352 546 5.7E-91 T 28-03-2018 IPR035401 Urocanase, C-terminal domain KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 CO689_RS03635 0eaba0cef6e003f16048ab732e6efd96 562 TIGRFAM TIGR01228 hutU: urocanate hydratase 10 554 2.4E-303 T 28-03-2018 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 CO689_RS03635 0eaba0cef6e003f16048ab732e6efd96 562 Pfam PF17391 Urocanase N-terminal domain 12 138 1.5E-61 T 28-03-2018 IPR035400 Urocanase, N-terminal domain KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 CO689_RS03635 0eaba0cef6e003f16048ab732e6efd96 562 PIRSF PIRSF001423 1 561 8.1E-295 T 28-03-2018 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 CO689_RS04535 5a295c55e2e08b0a4405b36eda4c370a 133 Pfam PF07070 SpoOM protein 2 132 3.6E-19 T 28-03-2018 IPR009776 Sporulation stage 0, protein M CO689_RS09155 ff034859264dd69c0b203d5a691e2ea7 479 SMART SM00028 16 49 1.7E-4 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CO689_RS09155 ff034859264dd69c0b203d5a691e2ea7 479 SMART SM00028 177 210 10.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CO689_RS09155 ff034859264dd69c0b203d5a691e2ea7 479 Pfam PF13181 Tetratricopeptide repeat 180 208 0.11 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CO689_RS09155 ff034859264dd69c0b203d5a691e2ea7 479 SUPERFAMILY SSF48452 15 223 1.26E-9 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CO689_RS09155 ff034859264dd69c0b203d5a691e2ea7 479 Gene3D G3DSA:1.25.40.10 134 325 1.5E-10 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CO689_RS09155 ff034859264dd69c0b203d5a691e2ea7 479 Gene3D G3DSA:1.25.40.10 12 106 3.3E-10 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CO689_RS03610 be3d4bc99ce63d4732154fb4a8a26804 203 Gene3D G3DSA:2.30.110.10 10 191 5.0E-48 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CO689_RS03610 be3d4bc99ce63d4732154fb4a8a26804 203 Pfam PF01613 Flavin reductase like domain 23 169 9.2E-24 T 28-03-2018 IPR002563 Flavin reductase like domain GO:0010181 CO689_RS03610 be3d4bc99ce63d4732154fb4a8a26804 203 SUPERFAMILY SSF50475 2 193 1.57E-46 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CO689_RS03610 be3d4bc99ce63d4732154fb4a8a26804 203 SMART SM00903 20 176 3.0E-27 T 28-03-2018 IPR002563 Flavin reductase like domain GO:0010181 CO689_RS09405 2b6fba62ad696612f7adc17e021bd300 434 TIGRFAM TIGR00933 2a38: potassium uptake protein, TrkH family 25 406 1.2E-99 T 28-03-2018 IPR004772 TrkH potassium transport family GO:0016021|GO:0022820|GO:0071805 CO689_RS09405 2b6fba62ad696612f7adc17e021bd300 434 Pfam PF02386 Cation transport protein 33 422 1.6E-50 T 28-03-2018 IPR003445 Cation transporter GO:0006812|GO:0008324|GO:0055085 CO689_RS01120 0575d387f475b02efaf0069b51def492 210 PIRSF PIRSF000498 1 207 5.0E-71 T 28-03-2018 IPR001783 Lumazine-binding protein KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CO689_RS01120 0575d387f475b02efaf0069b51def492 210 Gene3D G3DSA:2.40.30.20 1 88 1.8E-26 T 28-03-2018 IPR023366 ATP synthase subunit alpha-like domain KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CO689_RS01120 0575d387f475b02efaf0069b51def492 210 Gene3D G3DSA:2.40.30.20 93 190 9.5E-30 T 28-03-2018 IPR023366 ATP synthase subunit alpha-like domain KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CO689_RS01120 0575d387f475b02efaf0069b51def492 210 TIGRFAM TIGR00187 ribE: riboflavin synthase, alpha subunit 1 197 1.8E-66 T 28-03-2018 IPR001783 Lumazine-binding protein KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CO689_RS01120 0575d387f475b02efaf0069b51def492 210 Pfam PF00677 Lumazine binding domain 3 86 8.0E-21 T 28-03-2018 IPR026017 Lumazine-binding domain KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CO689_RS01120 0575d387f475b02efaf0069b51def492 210 Pfam PF00677 Lumazine binding domain 100 183 2.5E-21 T 28-03-2018 IPR026017 Lumazine-binding domain KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CO689_RS01120 0575d387f475b02efaf0069b51def492 210 SUPERFAMILY SSF63380 92 195 1.28E-28 T 28-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 CO689_RS01120 0575d387f475b02efaf0069b51def492 210 SUPERFAMILY SSF63380 1 88 9.35E-24 T 28-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 CO689_RS02610 1b7628a8a81c1cf143725870c7460185 220 SUPERFAMILY SSF51569 1 214 5.76E-85 T 28-03-2018 CO689_RS02610 1b7628a8a81c1cf143725870c7460185 220 Hamap MF_00114 Deoxyribose-phosphate aldolase [deoC]. 1 215 38.34 T 28-03-2018 IPR028581 Deoxyribose-phosphate aldolase type I GO:0004139 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180 CO689_RS02610 1b7628a8a81c1cf143725870c7460185 220 Pfam PF01791 DeoC/LacD family aldolase 6 208 2.6E-25 T 28-03-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 CO689_RS02610 1b7628a8a81c1cf143725870c7460185 220 TIGRFAM TIGR00126 deoC: deoxyribose-phosphate aldolase 3 212 2.1E-90 T 28-03-2018 IPR011343 Deoxyribose-phosphate aldolase GO:0004139|GO:0005737|GO:0009264 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180|Reactome: R-HSA-6798695|Reactome: R-HSA-71336 CO689_RS02610 1b7628a8a81c1cf143725870c7460185 220 SMART SM01133 2 213 2.7E-104 T 28-03-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 CO689_RS02610 1b7628a8a81c1cf143725870c7460185 220 PIRSF PIRSF001357 1 219 9.6E-81 T 28-03-2018 IPR011343 Deoxyribose-phosphate aldolase GO:0004139|GO:0005737|GO:0009264 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180|Reactome: R-HSA-6798695|Reactome: R-HSA-71336 CO689_RS02610 1b7628a8a81c1cf143725870c7460185 220 Gene3D G3DSA:3.20.20.70 1 216 2.3E-97 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CO689_RS07195 875da5748179e6f1f3950121e9b36a43 507 Gene3D G3DSA:3.40.30.10 1 92 5.1E-25 T 28-03-2018 CO689_RS07195 875da5748179e6f1f3950121e9b36a43 507 Gene3D G3DSA:3.50.50.60 436 507 4.4E-10 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CO689_RS07195 875da5748179e6f1f3950121e9b36a43 507 SUPERFAMILY SSF52833 104 191 8.6E-19 T 28-03-2018 IPR012336 Thioredoxin-like fold CO689_RS07195 875da5748179e6f1f3950121e9b36a43 507 SUPERFAMILY SSF52833 1 100 2.57E-28 T 28-03-2018 IPR012336 Thioredoxin-like fold CO689_RS07195 875da5748179e6f1f3950121e9b36a43 507 TIGRFAM TIGR03140 AhpF: alkyl hydroperoxide reductase subunit F 1 507 3.0E-232 T 28-03-2018 IPR012081 Alkyl hydroperoxide reductase subunit F GO:0000302|GO:0008785|GO:0016651|GO:0050660|GO:0051287|GO:0055114 CO689_RS07195 875da5748179e6f1f3950121e9b36a43 507 Gene3D G3DSA:3.50.50.60 328 435 3.0E-24 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CO689_RS07195 875da5748179e6f1f3950121e9b36a43 507 Gene3D G3DSA:3.50.50.60 194 327 1.1E-19 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CO689_RS07195 875da5748179e6f1f3950121e9b36a43 507 ProSitePatterns PS00573 Pyridine nucleotide-disulphide oxidoreductases class-II active site. 335 355 - T 28-03-2018 IPR008255 Pyridine nucleotide-disulphide oxidoreductase, class-II, active site GO:0016491|GO:0055114 CO689_RS07195 875da5748179e6f1f3950121e9b36a43 507 SUPERFAMILY SSF51905 195 503 8.64E-48 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CO689_RS07195 875da5748179e6f1f3950121e9b36a43 507 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 206 493 3.5E-44 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CO689_RS07195 875da5748179e6f1f3950121e9b36a43 507 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 431 447 1.0E-38 T 28-03-2018 CO689_RS07195 875da5748179e6f1f3950121e9b36a43 507 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 457 479 1.0E-38 T 28-03-2018 CO689_RS07195 875da5748179e6f1f3950121e9b36a43 507 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 305 323 1.0E-38 T 28-03-2018 CO689_RS07195 875da5748179e6f1f3950121e9b36a43 507 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 208 227 1.0E-38 T 28-03-2018 CO689_RS07195 875da5748179e6f1f3950121e9b36a43 507 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 347 365 1.0E-38 T 28-03-2018 CO689_RS07195 875da5748179e6f1f3950121e9b36a43 507 Pfam PF13192 Thioredoxin domain 123 183 5.2E-6 T 28-03-2018 IPR012336 Thioredoxin-like fold CO689_RS07195 875da5748179e6f1f3950121e9b36a43 507 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 306 314 1.2E-63 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CO689_RS07195 875da5748179e6f1f3950121e9b36a43 507 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 395 411 1.2E-63 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CO689_RS07195 875da5748179e6f1f3950121e9b36a43 507 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 259 269 1.2E-63 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CO689_RS07195 875da5748179e6f1f3950121e9b36a43 507 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 467 485 1.2E-63 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CO689_RS07195 875da5748179e6f1f3950121e9b36a43 507 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 343 367 1.2E-63 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CO689_RS07195 875da5748179e6f1f3950121e9b36a43 507 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 328 340 1.2E-63 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CO689_RS07195 875da5748179e6f1f3950121e9b36a43 507 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 239 254 1.2E-63 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CO689_RS07195 875da5748179e6f1f3950121e9b36a43 507 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 207 229 1.2E-63 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CO689_RS07195 875da5748179e6f1f3950121e9b36a43 507 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 433 454 1.2E-63 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CO689_RS07195 875da5748179e6f1f3950121e9b36a43 507 Gene3D G3DSA:3.40.30.10 101 193 2.8E-4 T 28-03-2018 CO689_RS07195 875da5748179e6f1f3950121e9b36a43 507 PIRSF PIRSF000238 1 507 1.5E-238 T 28-03-2018 IPR012081 Alkyl hydroperoxide reductase subunit F GO:0000302|GO:0008785|GO:0016651|GO:0050660|GO:0051287|GO:0055114 CO689_RS07560 0b0be722e42d41152deb83fbcb073b39 445 Gene3D G3DSA:3.90.100.10 340 445 1.2E-18 T 28-03-2018 IPR008286 Orn/Lys/Arg decarboxylase, C-terminal GO:0003824 CO689_RS07560 0b0be722e42d41152deb83fbcb073b39 445 Gene3D G3DSA:3.40.640.10 36 255 3.0E-23 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CO689_RS07560 0b0be722e42d41152deb83fbcb073b39 445 Pfam PF01276 Orn/Lys/Arg decarboxylase, major domain 4 260 5.8E-39 T 28-03-2018 IPR000310 Orn/Lys/Arg decarboxylase, major domain GO:0003824 CO689_RS07560 0b0be722e42d41152deb83fbcb073b39 445 Pfam PF03711 Orn/Lys/Arg decarboxylase, C-terminal domain 354 423 2.0E-7 T 28-03-2018 IPR008286 Orn/Lys/Arg decarboxylase, C-terminal GO:0003824 CO689_RS07560 0b0be722e42d41152deb83fbcb073b39 445 SUPERFAMILY SSF55904 307 441 3.53E-20 T 28-03-2018 IPR008286 Orn/Lys/Arg decarboxylase, C-terminal GO:0003824 CO689_RS07560 0b0be722e42d41152deb83fbcb073b39 445 SUPERFAMILY SSF53383 7 337 8.0E-48 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CO689_RS07065 f30345f2a1750d91da8af5022aa6d962 386 Pfam PF00155 Aminotransferase class I and II 30 377 1.2E-53 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CO689_RS07065 f30345f2a1750d91da8af5022aa6d962 386 SUPERFAMILY SSF53383 1 380 2.06E-86 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CO689_RS07065 f30345f2a1750d91da8af5022aa6d962 386 Gene3D G3DSA:3.90.1150.10 279 386 1.6E-22 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CO689_RS07065 f30345f2a1750d91da8af5022aa6d962 386 Gene3D G3DSA:3.40.640.10 67 278 4.6E-37 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CO689_RS07065 f30345f2a1750d91da8af5022aa6d962 386 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 231 244 - T 28-03-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 CO689_RS03720 8374c317f0635e9518de2d0a0fb274ec 615 ProSitePatterns PS00850 Glycine radical domain signature. 581 589 - T 28-03-2018 IPR019777 Formate C-acetyltransferase glycine radical, conserved site CO689_RS03720 8374c317f0635e9518de2d0a0fb274ec 615 Gene3D G3DSA:3.20.70.20 26 592 1.5E-193 T 28-03-2018 CO689_RS03720 8374c317f0635e9518de2d0a0fb274ec 615 SUPERFAMILY SSF51998 26 590 5.49E-185 T 28-03-2018 CO689_RS03720 8374c317f0635e9518de2d0a0fb274ec 615 Pfam PF13597 Anaerobic ribonucleoside-triphosphate reductase 21 610 2.0E-179 T 28-03-2018 IPR012833 Ribonucleoside-triphosphate reductase, anaerobic GO:0006260|GO:0008998|GO:0016491|GO:0055114 KEGG: 00230+1.17.4.2|KEGG: 00240+1.17.4.2 CO689_RS03720 8374c317f0635e9518de2d0a0fb274ec 615 TIGRFAM TIGR02487 NrdD: anaerobic ribonucleoside-triphosphate reductase 20 610 7.7E-179 T 28-03-2018 IPR012833 Ribonucleoside-triphosphate reductase, anaerobic GO:0006260|GO:0008998|GO:0016491|GO:0055114 KEGG: 00230+1.17.4.2|KEGG: 00240+1.17.4.2 CO689_RS09105 d741b3b9c0aa79176f57df5eccab1dd0 842 SUPERFAMILY SSF81767 231 354 1.27E-46 T 28-03-2018 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 CO689_RS09105 d741b3b9c0aa79176f57df5eccab1dd0 842 TIGRFAM TIGR00963 secA: preprotein translocase, SecA subunit 26 503 1.7E-241 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CO689_RS09105 d741b3b9c0aa79176f57df5eccab1dd0 842 Gene3D G3DSA:3.40.50.300 6 271 7.5E-51 T 28-03-2018 CO689_RS09105 d741b3b9c0aa79176f57df5eccab1dd0 842 Gene3D G3DSA:3.40.50.300 272 402 1.5E-8 T 28-03-2018 CO689_RS09105 d741b3b9c0aa79176f57df5eccab1dd0 842 Pfam PF07516 SecA Wing and Scaffold domain 574 780 2.0E-59 T 28-03-2018 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 CO689_RS09105 d741b3b9c0aa79176f57df5eccab1dd0 842 Gene3D G3DSA:3.10.450.50 679 842 4.2E-43 T 28-03-2018 CO689_RS09105 d741b3b9c0aa79176f57df5eccab1dd0 842 Hamap MF_01382 Protein translocase subunit SecA [secA]. 3 784 19.171 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CO689_RS09105 d741b3b9c0aa79176f57df5eccab1dd0 842 Gene3D G3DSA:3.40.50.300 403 590 7.2E-53 T 28-03-2018 CO689_RS09105 d741b3b9c0aa79176f57df5eccab1dd0 842 SUPERFAMILY SSF52540 10 232 1.06E-74 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CO689_RS09105 d741b3b9c0aa79176f57df5eccab1dd0 842 SUPERFAMILY SSF52540 354 401 1.06E-74 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CO689_RS09105 d741b3b9c0aa79176f57df5eccab1dd0 842 PRINTS PR00906 SecA protein signature 174 194 3.8E-69 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CO689_RS09105 d741b3b9c0aa79176f57df5eccab1dd0 842 PRINTS PR00906 SecA protein signature 121 131 3.8E-69 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CO689_RS09105 d741b3b9c0aa79176f57df5eccab1dd0 842 PRINTS PR00906 SecA protein signature 105 119 3.8E-69 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CO689_RS09105 d741b3b9c0aa79176f57df5eccab1dd0 842 PRINTS PR00906 SecA protein signature 67 91 3.8E-69 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CO689_RS09105 d741b3b9c0aa79176f57df5eccab1dd0 842 PRINTS PR00906 SecA protein signature 362 379 3.8E-69 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CO689_RS09105 d741b3b9c0aa79176f57df5eccab1dd0 842 PRINTS PR00906 SecA protein signature 399 412 3.8E-69 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CO689_RS09105 d741b3b9c0aa79176f57df5eccab1dd0 842 PRINTS PR00906 SecA protein signature 325 347 3.8E-69 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CO689_RS09105 d741b3b9c0aa79176f57df5eccab1dd0 842 SUPERFAMILY SSF81886 820 832 9.81E-72 T 28-03-2018 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 CO689_RS09105 d741b3b9c0aa79176f57df5eccab1dd0 842 SUPERFAMILY SSF81886 577 792 9.81E-72 T 28-03-2018 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 CO689_RS09105 d741b3b9c0aa79176f57df5eccab1dd0 842 Pfam PF01043 SecA preprotein cross-linking domain 236 344 3.9E-40 T 28-03-2018 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 CO689_RS09105 d741b3b9c0aa79176f57df5eccab1dd0 842 Pfam PF02810 SEC-C motif 824 842 1.1E-9 T 28-03-2018 IPR004027 SEC-C motif CO689_RS09105 d741b3b9c0aa79176f57df5eccab1dd0 842 Gene3D G3DSA:1.10.3060.10 591 672 6.6E-27 T 28-03-2018 CO689_RS09105 d741b3b9c0aa79176f57df5eccab1dd0 842 SMART SM00957 4 388 4.6E-265 T 28-03-2018 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 CO689_RS09105 d741b3b9c0aa79176f57df5eccab1dd0 842 SUPERFAMILY SSF52540 402 575 3.82E-52 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CO689_RS09105 d741b3b9c0aa79176f57df5eccab1dd0 842 Pfam PF07517 SecA DEAD-like domain 7 388 9.0E-122 T 28-03-2018 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 CO689_RS09105 d741b3b9c0aa79176f57df5eccab1dd0 842 SMART SM00958 232 344 2.2E-64 T 28-03-2018 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 CO689_RS09105 d741b3b9c0aa79176f57df5eccab1dd0 842 ProSitePatterns PS01312 SecA family signature. 486 501 - T 28-03-2018 IPR020937 SecA conserved site GO:0006605|GO:0006886|GO:0016020 CO689_RS06615 7111e12d6f15e5da7f9a9ad11ecdc776 174 SUPERFAMILY SSF54593 4 160 4.03E-25 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CO689_RS06615 7111e12d6f15e5da7f9a9ad11ecdc776 174 Gene3D G3DSA:3.10.180.10 2 171 9.4E-30 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CO689_RS06615 7111e12d6f15e5da7f9a9ad11ecdc776 174 Pfam PF13669 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 8 127 3.4E-12 T 28-03-2018 CO689_RS10755 f209185310112b10ba994814912f6dae 188 SUPERFAMILY SSF53328 3 187 2.22E-59 T 28-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CO689_RS10755 f209185310112b10ba994814912f6dae 188 Gene3D G3DSA:3.40.50.170 1 188 8.2E-64 T 28-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CO689_RS10755 f209185310112b10ba994814912f6dae 188 TIGRFAM TIGR00639 PurN: phosphoribosylglycinamide formyltransferase 3 187 2.9E-66 T 28-03-2018 IPR004607 Phosphoribosylglycinamide formyltransferase GO:0004644|GO:0006189 KEGG: 00230+2.1.2.2|KEGG: 00670+2.1.2.2|MetaCyc: PWY-6121|MetaCyc: PWY-6613|Reactome: R-HSA-73817 CO689_RS10755 f209185310112b10ba994814912f6dae 188 Pfam PF00551 Formyl transferase 3 183 2.1E-57 T 28-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CO689_RS10755 f209185310112b10ba994814912f6dae 188 Hamap MF_01930 Phosphoribosylglycinamide formyltransferase [purN]. 3 188 27.932 T 28-03-2018 IPR004607 Phosphoribosylglycinamide formyltransferase GO:0004644|GO:0006189 KEGG: 00230+2.1.2.2|KEGG: 00670+2.1.2.2|MetaCyc: PWY-6121|MetaCyc: PWY-6613|Reactome: R-HSA-73817 CO689_RS08455 07cc93f41ffffa38f9b72c5226d3203b 251 Pfam PF03808 Glycosyl transferase WecB/TagA/CpsF family 69 233 4.3E-55 T 28-03-2018 IPR004629 Glycosyl transferase WecB/TagA/CpsF GO:0009058 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622 CO689_RS08455 07cc93f41ffffa38f9b72c5226d3203b 251 TIGRFAM TIGR00696 wecG_tagA_cpsF: glycosyltransferase, WecB/TagA/CpsF family 64 239 1.0E-49 T 28-03-2018 IPR004629 Glycosyl transferase WecB/TagA/CpsF GO:0009058 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622 CO689_RS08455 07cc93f41ffffa38f9b72c5226d3203b 251 Hamap MF_02070 N-acetylglucosaminyldiphosphoundecaprenol N-acetyl-beta-D-mannosaminyltransferase. 10 248 57.193 T 28-03-2018 IPR034714 N-acetylglucosaminyldiphosphoundecaprenol N-acetyl-beta-D-mannosaminyltransferase GO:0047244 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|MetaCyc: PWY-7815|MetaCyc: PWY-7816|MetaCyc: PWY-7819 CO689_RS07670 5ad7e45507e7f0cc7776ea433df851fd 666 PRINTS PR01041 Methionyl-tRNA synthetase signature 268 283 3.4E-31 T 28-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 CO689_RS07670 5ad7e45507e7f0cc7776ea433df851fd 666 PRINTS PR01041 Methionyl-tRNA synthetase signature 235 246 3.4E-31 T 28-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 CO689_RS07670 5ad7e45507e7f0cc7776ea433df851fd 666 PRINTS PR01041 Methionyl-tRNA synthetase signature 40 54 3.4E-31 T 28-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 CO689_RS07670 5ad7e45507e7f0cc7776ea433df851fd 666 PRINTS PR01041 Methionyl-tRNA synthetase signature 8 21 3.4E-31 T 28-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 CO689_RS07670 5ad7e45507e7f0cc7776ea433df851fd 666 PRINTS PR01041 Methionyl-tRNA synthetase signature 88 99 3.4E-31 T 28-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 CO689_RS07670 5ad7e45507e7f0cc7776ea433df851fd 666 PRINTS PR01041 Methionyl-tRNA synthetase signature 360 371 3.4E-31 T 28-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 CO689_RS07670 5ad7e45507e7f0cc7776ea433df851fd 666 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 15 24 - T 28-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 CO689_RS07670 5ad7e45507e7f0cc7776ea433df851fd 666 TIGRFAM TIGR00398 metG: methionine--tRNA ligase 6 492 8.1E-168 T 28-03-2018 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 CO689_RS07670 5ad7e45507e7f0cc7776ea433df851fd 666 SUPERFAMILY SSF50249 561 665 2.15E-30 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CO689_RS07670 5ad7e45507e7f0cc7776ea433df851fd 666 TIGRFAM TIGR00399 metG_C_term: methionine--tRNA ligase, beta subunit 542 665 4.4E-44 T 28-03-2018 IPR004495 Methionyl-tRNA synthetase, beta subunit, C-terminal GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 CO689_RS07670 5ad7e45507e7f0cc7776ea433df851fd 666 SUPERFAMILY SSF52374 3 359 5.89E-111 T 28-03-2018 CO689_RS07670 5ad7e45507e7f0cc7776ea433df851fd 666 Pfam PF08264 Anticodon-binding domain of tRNA 402 499 1.1E-6 T 28-03-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 CO689_RS07670 5ad7e45507e7f0cc7776ea433df851fd 666 Hamap MF_01228 Methionine--tRNA ligase [metG]. 1 518 50.23 T 28-03-2018 IPR023457 Methionine-tRNA synthetase, type 2 GO:0004825 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 CO689_RS07670 5ad7e45507e7f0cc7776ea433df851fd 666 Gene3D G3DSA:1.10.730.10 357 525 4.5E-38 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CO689_RS07670 5ad7e45507e7f0cc7776ea433df851fd 666 Pfam PF09334 tRNA synthetases class I (M) 6 372 1.8E-115 T 28-03-2018 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 CO689_RS07670 5ad7e45507e7f0cc7776ea433df851fd 666 Gene3D G3DSA:3.40.50.620 3 356 2.3E-100 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CO689_RS07670 5ad7e45507e7f0cc7776ea433df851fd 666 Pfam PF01588 Putative tRNA binding domain 573 663 7.1E-27 T 28-03-2018 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 CO689_RS07670 5ad7e45507e7f0cc7776ea433df851fd 666 Gene3D G3DSA:2.40.50.140 558 666 3.8E-30 T 28-03-2018 CO689_RS07670 5ad7e45507e7f0cc7776ea433df851fd 666 SUPERFAMILY SSF47323 362 579 1.08E-41 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CO689_RS08750 ba60ca82bcfd6d68a749080e94d8fe97 555 TIGRFAM TIGR02868 CydC: thiol reductant ABC exporter, CydC subunit 12 514 7.9E-104 T 28-03-2018 IPR014223 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease/ATP-binding protein CydC GO:0006810|GO:0016021|GO:0042626 CO689_RS08750 ba60ca82bcfd6d68a749080e94d8fe97 555 ProSitePatterns PS00211 ABC transporters family signature. 458 472 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CO689_RS08750 ba60ca82bcfd6d68a749080e94d8fe97 555 SUPERFAMILY SSF90123 13 315 3.14E-37 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CO689_RS08750 ba60ca82bcfd6d68a749080e94d8fe97 555 Gene3D G3DSA:1.20.1560.10 7 322 5.8E-26 T 28-03-2018 CO689_RS08750 ba60ca82bcfd6d68a749080e94d8fe97 555 SMART SM00382 355 530 6.4E-14 T 28-03-2018 IPR003593 AAA+ ATPase domain CO689_RS08750 ba60ca82bcfd6d68a749080e94d8fe97 555 Pfam PF00664 ABC transporter transmembrane region 15 283 9.5E-13 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CO689_RS08750 ba60ca82bcfd6d68a749080e94d8fe97 555 Gene3D G3DSA:3.40.50.300 324 555 1.5E-59 T 28-03-2018 CO689_RS08750 ba60ca82bcfd6d68a749080e94d8fe97 555 Pfam PF00005 ABC transporter 346 485 2.1E-32 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CO689_RS08750 ba60ca82bcfd6d68a749080e94d8fe97 555 SUPERFAMILY SSF52540 307 551 5.55E-56 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CO689_RS13825 a19e0dbe6c0dfd591eb9a3fd549baebc 372 SUPERFAMILY SSF48256 4 372 1.83E-128 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 CO689_RS13825 a19e0dbe6c0dfd591eb9a3fd549baebc 372 PIRSF PIRSF001369 1 372 2.1E-147 T 28-03-2018 IPR024176 Citrate synthase, bacterial-type CO689_RS13825 a19e0dbe6c0dfd591eb9a3fd549baebc 372 Gene3D G3DSA:1.10.580.10 12 261 1.6E-82 T 28-03-2018 IPR016142 Citrate synthase-like, large alpha subdomain CO689_RS13825 a19e0dbe6c0dfd591eb9a3fd549baebc 372 Pfam PF00285 Citrate synthase, C-terminal domain 7 355 2.4E-127 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 CO689_RS13825 a19e0dbe6c0dfd591eb9a3fd549baebc 372 Gene3D G3DSA:1.10.580.10 292 352 3.5E-10 T 28-03-2018 IPR016142 Citrate synthase-like, large alpha subdomain CO689_RS13825 a19e0dbe6c0dfd591eb9a3fd549baebc 372 ProSitePatterns PS00480 Citrate synthase signature. 255 267 - T 28-03-2018 IPR019810 Citrate synthase active site GO:0006099|GO:0046912 Reactome: R-HSA-1268020|Reactome: R-HSA-71403 CO689_RS13825 a19e0dbe6c0dfd591eb9a3fd549baebc 372 PRINTS PR00143 Citrate synthase signature 173 188 4.8E-39 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 CO689_RS13825 a19e0dbe6c0dfd591eb9a3fd549baebc 372 PRINTS PR00143 Citrate synthase signature 305 321 4.8E-39 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 CO689_RS13825 a19e0dbe6c0dfd591eb9a3fd549baebc 372 PRINTS PR00143 Citrate synthase signature 195 223 4.8E-39 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 CO689_RS13825 a19e0dbe6c0dfd591eb9a3fd549baebc 372 PRINTS PR00143 Citrate synthase signature 325 339 4.8E-39 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 CO689_RS13825 a19e0dbe6c0dfd591eb9a3fd549baebc 372 PRINTS PR00143 Citrate synthase signature 124 137 4.8E-39 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 CO689_RS13825 a19e0dbe6c0dfd591eb9a3fd549baebc 372 PRINTS PR00143 Citrate synthase signature 248 268 4.8E-39 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 CO689_RS13825 a19e0dbe6c0dfd591eb9a3fd549baebc 372 TIGRFAM TIGR01800 cit_synth_II: 2-methylcitrate synthase/citrate synthase II 6 372 3.6E-153 T 28-03-2018 IPR011278 2-methylcitrate synthase/citrate synthase type I GO:0005737|GO:0046912 CO689_RS08740 f20e2689635f3a75636876a6fc03a6b7 299 TIGRFAM TIGR00753 undec_PP_bacA: undecaprenyl-diphosphatase UppP 9 282 2.3E-81 T 28-03-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 CO689_RS08740 f20e2689635f3a75636876a6fc03a6b7 299 Pfam PF02673 Bacitracin resistance protein BacA 9 284 1.5E-77 T 28-03-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 CO689_RS08740 f20e2689635f3a75636876a6fc03a6b7 299 Hamap MF_01006 Undecaprenyl-diphosphatase [uppP]. 4 290 17.395 T 28-03-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 CO689_RS07080 bd3fd1ceac96dc5bafd1d239c2be9dca 613 SUPERFAMILY SSF82282 2 362 3.4E-99 T 28-03-2018 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 CO689_RS07080 bd3fd1ceac96dc5bafd1d239c2be9dca 613 SUPERFAMILY SSF51730 318 601 2.35E-68 T 28-03-2018 IPR029041 FAD-linked oxidoreductase-like CO689_RS07080 bd3fd1ceac96dc5bafd1d239c2be9dca 613 Gene3D G3DSA:3.20.20.220 301 612 1.0E-67 T 28-03-2018 IPR029041 FAD-linked oxidoreductase-like CO689_RS07080 bd3fd1ceac96dc5bafd1d239c2be9dca 613 Pfam PF02219 Methylenetetrahydrofolate reductase 321 581 1.8E-31 T 28-03-2018 IPR003171 Methylenetetrahydrofolate reductase GO:0004489|GO:0006555|GO:0055114 KEGG: 00670+1.5.1.20|KEGG: 00720+1.5.1.20|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 CO689_RS07080 bd3fd1ceac96dc5bafd1d239c2be9dca 613 Pfam PF02574 Homocysteine S-methyltransferase 13 282 1.5E-56 T 28-03-2018 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 CO689_RS07080 bd3fd1ceac96dc5bafd1d239c2be9dca 613 Gene3D G3DSA:3.20.20.330 1 294 8.4E-76 T 28-03-2018 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 CO689_RS07610 9ed0e73100d8e771368dacb9967f714e 133 Pfam PF07901 Protein of unknown function (DUF1672) 1 130 4.9E-22 T 28-03-2018 IPR012873 Protein of unknown function DUF1672 CO689_RS10035 9beb75d6aff966273e3c11f69bb83a9e 3782 SUPERFAMILY SSF49899 7 134 6.73E-5 T 28-03-2018 IPR013320 Concanavalin A-like lectin/glucanase domain CO689_RS10035 9beb75d6aff966273e3c11f69bb83a9e 3782 Gene3D G3DSA:2.60.40.10 303 393 1.5E-13 T 28-03-2018 IPR013783 Immunoglobulin-like fold CO689_RS10035 9beb75d6aff966273e3c11f69bb83a9e 3782 Gene3D G3DSA:2.60.40.10 206 302 2.7E-12 T 28-03-2018 IPR013783 Immunoglobulin-like fold CO689_RS10035 9beb75d6aff966273e3c11f69bb83a9e 3782 Gene3D G3DSA:1.20.1270.90 1384 1447 4.7E-7 T 28-03-2018 CO689_RS10035 9beb75d6aff966273e3c11f69bb83a9e 3782 Gene3D G3DSA:1.20.1270.90 3629 3696 1.3E-6 T 28-03-2018 CO689_RS10035 9beb75d6aff966273e3c11f69bb83a9e 3782 Gene3D G3DSA:1.20.1270.90 3214 3277 5.5E-7 T 28-03-2018 CO689_RS10035 9beb75d6aff966273e3c11f69bb83a9e 3782 Gene3D G3DSA:1.20.1270.90 3427 3480 1.4E-9 T 28-03-2018 CO689_RS10035 9beb75d6aff966273e3c11f69bb83a9e 3782 Gene3D G3DSA:1.20.1270.90 2725 2776 5.8E-8 T 28-03-2018 CO689_RS10035 9beb75d6aff966273e3c11f69bb83a9e 3782 Gene3D G3DSA:1.20.1270.90 1312 1367 5.8E-7 T 28-03-2018 CO689_RS10035 9beb75d6aff966273e3c11f69bb83a9e 3782 Gene3D G3DSA:1.20.1270.90 1448 1510 2.5E-9 T 28-03-2018 CO689_RS10035 9beb75d6aff966273e3c11f69bb83a9e 3782 Gene3D G3DSA:1.20.1270.90 1584 1644 6.2E-9 T 28-03-2018 CO689_RS10035 9beb75d6aff966273e3c11f69bb83a9e 3782 Gene3D G3DSA:1.20.1270.90 2439 2495 1.4E-9 T 28-03-2018 CO689_RS10035 9beb75d6aff966273e3c11f69bb83a9e 3782 Gene3D G3DSA:1.20.1270.90 2513 2580 1.4E-5 T 28-03-2018 CO689_RS10035 9beb75d6aff966273e3c11f69bb83a9e 3782 Gene3D G3DSA:1.20.1270.90 3278 3339 1.6E-10 T 28-03-2018 CO689_RS10035 9beb75d6aff966273e3c11f69bb83a9e 3782 Gene3D G3DSA:1.20.1270.90 2083 2151 5.6E-7 T 28-03-2018 CO689_RS10035 9beb75d6aff966273e3c11f69bb83a9e 3782 Gene3D G3DSA:1.20.1270.90 2020 2072 6.5E-10 T 28-03-2018 CO689_RS10035 9beb75d6aff966273e3c11f69bb83a9e 3782 Gene3D G3DSA:1.20.1270.90 3491 3559 2.5E-9 T 28-03-2018 CO689_RS10035 9beb75d6aff966273e3c11f69bb83a9e 3782 Gene3D G3DSA:1.20.1270.90 3003 3064 1.1E-11 T 28-03-2018 CO689_RS10035 9beb75d6aff966273e3c11f69bb83a9e 3782 Gene3D G3DSA:1.20.1270.90 2581 2643 1.2E-6 T 28-03-2018 CO689_RS10035 9beb75d6aff966273e3c11f69bb83a9e 3782 Gene3D G3DSA:1.20.1270.90 2152 2214 8.3E-11 T 28-03-2018 CO689_RS10035 9beb75d6aff966273e3c11f69bb83a9e 3782 Gene3D G3DSA:1.20.1270.90 2862 2923 1.3E-10 T 28-03-2018 CO689_RS10035 9beb75d6aff966273e3c11f69bb83a9e 3782 Gene3D G3DSA:1.20.1270.90 3560 3621 1.4E-9 T 28-03-2018 CO689_RS10035 9beb75d6aff966273e3c11f69bb83a9e 3782 Gene3D G3DSA:1.20.1270.90 2793 2861 2.1E-8 T 28-03-2018 CO689_RS10035 9beb75d6aff966273e3c11f69bb83a9e 3782 Gene3D G3DSA:1.20.1270.90 1027 1085 1.9E-7 T 28-03-2018 CO689_RS10035 9beb75d6aff966273e3c11f69bb83a9e 3782 Gene3D G3DSA:1.20.1270.70 2930 3002 3.2E-7 T 28-03-2018 CO689_RS10035 9beb75d6aff966273e3c11f69bb83a9e 3782 Gene3D G3DSA:1.20.1270.70 3071 3143 2.9E-9 T 28-03-2018 CO689_RS10035 9beb75d6aff966273e3c11f69bb83a9e 3782 Gene3D G3DSA:1.20.1270.70 1098 1170 4.7E-7 T 28-03-2018 CO689_RS10035 9beb75d6aff966273e3c11f69bb83a9e 3782 Gene3D G3DSA:1.20.1270.70 1657 1729 1.8E-5 T 28-03-2018 CO689_RS10035 9beb75d6aff966273e3c11f69bb83a9e 3782 Gene3D G3DSA:1.20.1270.70 607 669 3.8E-10 T 28-03-2018 CO689_RS10035 9beb75d6aff966273e3c11f69bb83a9e 3782 Gene3D G3DSA:1.20.1270.70 816 888 8.4E-6 T 28-03-2018 CO689_RS10035 9beb75d6aff966273e3c11f69bb83a9e 3782 Pfam PF05345 Putative Ig domain 253 291 1.4E-8 T 28-03-2018 IPR008009 Putative Ig CO689_RS10035 9beb75d6aff966273e3c11f69bb83a9e 3782 Pfam PF05345 Putative Ig domain 342 379 2.3E-9 T 28-03-2018 IPR008009 Putative Ig CO689_RS10035 9beb75d6aff966273e3c11f69bb83a9e 3782 Gene3D G3DSA:2.60.120.200 1 154 4.3E-5 T 28-03-2018 CO689_RS10035 9beb75d6aff966273e3c11f69bb83a9e 3782 Gene3D G3DSA:1.20.1270.90 751 803 1.8E-5 T 28-03-2018 CO689_RS10035 9beb75d6aff966273e3c11f69bb83a9e 3782 Gene3D G3DSA:1.20.1270.90 1877 1925 3.7E-8 T 28-03-2018 CO689_RS10035 9beb75d6aff966273e3c11f69bb83a9e 3782 Pfam PF00746 LPXTG cell wall anchor motif 3735 3777 6.9E-5 T 28-03-2018 IPR019948 Gram-positive LPXTG cell wall anchor CO689_RS10035 9beb75d6aff966273e3c11f69bb83a9e 3782 SUPERFAMILY SSF49313 218 305 1.07E-9 T 28-03-2018 IPR015919 Cadherin-like GO:0005509|GO:0016020 CO689_RS10035 9beb75d6aff966273e3c11f69bb83a9e 3782 SUPERFAMILY SSF49313 327 393 1.88E-11 T 28-03-2018 IPR015919 Cadherin-like GO:0005509|GO:0016020 CO689_RS10035 9beb75d6aff966273e3c11f69bb83a9e 3782 Gene3D G3DSA:1.20.1270.90 531 606 1.9E-6 T 28-03-2018 CO689_RS10035 9beb75d6aff966273e3c11f69bb83a9e 3782 Gene3D G3DSA:1.20.1270.90 2301 2369 7.2E-8 T 28-03-2018 CO689_RS10035 9beb75d6aff966273e3c11f69bb83a9e 3782 Gene3D G3DSA:1.20.1270.90 2231 2300 1.6E-7 T 28-03-2018 CO689_RS10035 9beb75d6aff966273e3c11f69bb83a9e 3782 Gene3D G3DSA:1.20.1270.90 2370 2438 2.8E-7 T 28-03-2018 CO689_RS10035 9beb75d6aff966273e3c11f69bb83a9e 3782 Gene3D G3DSA:1.20.1270.90 1800 1876 5.5E-8 T 28-03-2018 CO689_RS10035 9beb75d6aff966273e3c11f69bb83a9e 3782 Gene3D G3DSA:1.20.1270.90 1516 1583 3.7E-8 T 28-03-2018 CO689_RS10035 9beb75d6aff966273e3c11f69bb83a9e 3782 Gene3D G3DSA:1.20.1270.90 1171 1240 7.3E-8 T 28-03-2018 CO689_RS10035 9beb75d6aff966273e3c11f69bb83a9e 3782 Gene3D G3DSA:1.20.1270.90 1730 1799 8.6E-8 T 28-03-2018 CO689_RS10035 9beb75d6aff966273e3c11f69bb83a9e 3782 Gene3D G3DSA:1.20.1270.90 3144 3213 1.4E-7 T 28-03-2018 CO689_RS10035 9beb75d6aff966273e3c11f69bb83a9e 3782 Gene3D G3DSA:1.20.1270.90 1241 1311 2.6E-8 T 28-03-2018 CO689_RS10035 9beb75d6aff966273e3c11f69bb83a9e 3782 Gene3D G3DSA:1.20.1270.90 889 957 8.3E-9 T 28-03-2018 CO689_RS10035 9beb75d6aff966273e3c11f69bb83a9e 3782 Gene3D G3DSA:1.20.1270.90 2649 2724 1.9E-7 T 28-03-2018 CO689_RS10035 9beb75d6aff966273e3c11f69bb83a9e 3782 Gene3D G3DSA:1.20.1270.90 463 530 1.0E-4 T 28-03-2018 CO689_RS10035 9beb75d6aff966273e3c11f69bb83a9e 3782 Gene3D G3DSA:1.20.1270.90 3350 3426 3.2E-11 T 28-03-2018 CO689_RS10035 9beb75d6aff966273e3c11f69bb83a9e 3782 Gene3D G3DSA:1.20.1270.90 958 1026 9.9E-8 T 28-03-2018 CO689_RS10035 9beb75d6aff966273e3c11f69bb83a9e 3782 Gene3D G3DSA:1.20.1270.90 1942 2019 1.2E-9 T 28-03-2018 CO689_RS10035 9beb75d6aff966273e3c11f69bb83a9e 3782 Gene3D G3DSA:1.20.1270.90 394 462 3.3E-6 T 28-03-2018 CO689_RS10035 9beb75d6aff966273e3c11f69bb83a9e 3782 Gene3D G3DSA:1.20.1270.90 676 750 5.2E-11 T 28-03-2018 CO689_RS10035 9beb75d6aff966273e3c11f69bb83a9e 3782 Pfam PF07554 FIVAR domain 677 737 2.7E-4 T 28-03-2018 CO689_RS10035 9beb75d6aff966273e3c11f69bb83a9e 3782 Pfam PF07554 FIVAR domain 1449 1510 4.5E-4 T 28-03-2018 CO689_RS10035 9beb75d6aff966273e3c11f69bb83a9e 3782 Pfam PF07554 FIVAR domain 746 802 0.2 T 28-03-2018 CO689_RS10035 9beb75d6aff966273e3c11f69bb83a9e 3782 Pfam PF07554 FIVAR domain 3420 3480 0.0013 T 28-03-2018 CO689_RS10035 9beb75d6aff966273e3c11f69bb83a9e 3782 Pfam PF07554 FIVAR domain 2582 2643 0.0089 T 28-03-2018 CO689_RS10035 9beb75d6aff966273e3c11f69bb83a9e 3782 Pfam PF07554 FIVAR domain 2235 2296 0.09 T 28-03-2018 CO689_RS10035 9beb75d6aff966273e3c11f69bb83a9e 3782 Pfam PF07554 FIVAR domain 3495 3556 1.6E-4 T 28-03-2018 CO689_RS10035 9beb75d6aff966273e3c11f69bb83a9e 3782 Pfam PF07554 FIVAR domain 1307 1367 0.26 T 28-03-2018 CO689_RS10035 9beb75d6aff966273e3c11f69bb83a9e 3782 Pfam PF07554 FIVAR domain 3214 3274 0.097 T 28-03-2018 CO689_RS10035 9beb75d6aff966273e3c11f69bb83a9e 3782 Pfam PF07554 FIVAR domain 2516 2578 0.085 T 28-03-2018 CO689_RS10035 9beb75d6aff966273e3c11f69bb83a9e 3782 Pfam PF07554 FIVAR domain 1387 1448 0.013 T 28-03-2018 CO689_RS10035 9beb75d6aff966273e3c11f69bb83a9e 3782 Pfam PF07554 FIVAR domain 3632 3693 0.041 T 28-03-2018 CO689_RS10035 9beb75d6aff966273e3c11f69bb83a9e 3782 Pfam PF07554 FIVAR domain 1106 1167 0.0092 T 28-03-2018 CO689_RS10035 9beb75d6aff966273e3c11f69bb83a9e 3782 Pfam PF07554 FIVAR domain 1172 1233 1.8E-4 T 28-03-2018 CO689_RS10035 9beb75d6aff966273e3c11f69bb83a9e 3782 Pfam PF07554 FIVAR domain 2718 2777 0.078 T 28-03-2018 CO689_RS10035 9beb75d6aff966273e3c11f69bb83a9e 3782 Pfam PF07554 FIVAR domain 2436 2496 0.096 T 28-03-2018 CO689_RS10035 9beb75d6aff966273e3c11f69bb83a9e 3782 Pfam PF07554 FIVAR domain 3280 3339 3.6E-4 T 28-03-2018 CO689_RS10035 9beb75d6aff966273e3c11f69bb83a9e 3782 Pfam PF07554 FIVAR domain 2863 2923 0.0014 T 28-03-2018 CO689_RS10035 9beb75d6aff966273e3c11f69bb83a9e 3782 Pfam PF07554 FIVAR domain 1241 1302 0.027 T 28-03-2018 CO689_RS10035 9beb75d6aff966273e3c11f69bb83a9e 3782 Pfam PF07554 FIVAR domain 1731 1792 3.6E-4 T 28-03-2018 CO689_RS10035 9beb75d6aff966273e3c11f69bb83a9e 3782 Pfam PF07554 FIVAR domain 2797 2858 0.014 T 28-03-2018 CO689_RS10035 9beb75d6aff966273e3c11f69bb83a9e 3782 Pfam PF07554 FIVAR domain 1866 1925 0.36 T 28-03-2018 CO689_RS10035 9beb75d6aff966273e3c11f69bb83a9e 3782 Pfam PF07554 FIVAR domain 2651 2711 0.43 T 28-03-2018 CO689_RS10035 9beb75d6aff966273e3c11f69bb83a9e 3782 Pfam PF07554 FIVAR domain 824 885 0.093 T 28-03-2018 CO689_RS10035 9beb75d6aff966273e3c11f69bb83a9e 3782 Pfam PF07554 FIVAR domain 1518 1579 0.0067 T 28-03-2018 CO689_RS10035 9beb75d6aff966273e3c11f69bb83a9e 3782 Pfam PF07554 FIVAR domain 3145 3206 0.0035 T 28-03-2018 CO689_RS10035 9beb75d6aff966273e3c11f69bb83a9e 3782 Pfam PF07554 FIVAR domain 959 1020 0.015 T 28-03-2018 CO689_RS10035 9beb75d6aff966273e3c11f69bb83a9e 3782 Pfam PF07554 FIVAR domain 1665 1727 0.042 T 28-03-2018 CO689_RS10035 9beb75d6aff966273e3c11f69bb83a9e 3782 Pfam PF07554 FIVAR domain 890 951 0.046 T 28-03-2018 CO689_RS10035 9beb75d6aff966273e3c11f69bb83a9e 3782 Pfam PF07554 FIVAR domain 3079 3140 3.9E-5 T 28-03-2018 CO689_RS10035 9beb75d6aff966273e3c11f69bb83a9e 3782 Pfam PF07554 FIVAR domain 2938 2999 0.22 T 28-03-2018 CO689_RS10035 9beb75d6aff966273e3c11f69bb83a9e 3782 Pfam PF07554 FIVAR domain 531 603 0.36 T 28-03-2018 CO689_RS10035 9beb75d6aff966273e3c11f69bb83a9e 3782 Pfam PF07554 FIVAR domain 2153 2214 1.0E-4 T 28-03-2018 CO689_RS10035 9beb75d6aff966273e3c11f69bb83a9e 3782 Pfam PF07554 FIVAR domain 1946 2007 0.0012 T 28-03-2018 CO689_RS10035 9beb75d6aff966273e3c11f69bb83a9e 3782 Pfam PF07554 FIVAR domain 1584 1644 0.099 T 28-03-2018 CO689_RS10035 9beb75d6aff966273e3c11f69bb83a9e 3782 Pfam PF07554 FIVAR domain 397 459 0.21 T 28-03-2018 CO689_RS10035 9beb75d6aff966273e3c11f69bb83a9e 3782 Pfam PF07554 FIVAR domain 3004 3064 2.5E-4 T 28-03-2018 CO689_RS10035 9beb75d6aff966273e3c11f69bb83a9e 3782 Pfam PF07554 FIVAR domain 3354 3415 2.3E-5 T 28-03-2018 CO689_RS10035 9beb75d6aff966273e3c11f69bb83a9e 3782 Pfam PF07554 FIVAR domain 2013 2072 0.0043 T 28-03-2018 CO689_RS10035 9beb75d6aff966273e3c11f69bb83a9e 3782 Pfam PF07554 FIVAR domain 1800 1860 0.0097 T 28-03-2018 CO689_RS10035 9beb75d6aff966273e3c11f69bb83a9e 3782 Pfam PF07554 FIVAR domain 2370 2430 0.38 T 28-03-2018 CO689_RS10035 9beb75d6aff966273e3c11f69bb83a9e 3782 Pfam PF07554 FIVAR domain 2087 2148 0.0012 T 28-03-2018 CO689_RS10035 9beb75d6aff966273e3c11f69bb83a9e 3782 Pfam PF07554 FIVAR domain 608 669 2.0E-5 T 28-03-2018 CO689_RS10035 9beb75d6aff966273e3c11f69bb83a9e 3782 Pfam PF07554 FIVAR domain 2301 2362 0.019 T 28-03-2018 CO689_RS10035 9beb75d6aff966273e3c11f69bb83a9e 3782 Pfam PF07554 FIVAR domain 1025 1085 0.24 T 28-03-2018 CO689_RS10035 9beb75d6aff966273e3c11f69bb83a9e 3782 Pfam PF07554 FIVAR domain 3561 3621 0.003 T 28-03-2018 CO689_RS13380 21352113a7ac84b023d348a052df3518 365 TIGRFAM TIGR03597 GTPase_YqeH: ribosome biogenesis GTPase YqeH 5 364 3.5E-151 T 28-03-2018 IPR019988 GTP-binding protein, riobosome biogenesis, YqeH CO689_RS13380 21352113a7ac84b023d348a052df3518 365 Gene3D G3DSA:3.40.50.300 55 223 1.3E-34 T 28-03-2018 CO689_RS13380 21352113a7ac84b023d348a052df3518 365 Pfam PF01926 50S ribosome-binding GTPase 161 232 6.7E-14 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CO689_RS13380 21352113a7ac84b023d348a052df3518 365 SUPERFAMILY SSF52540 61 279 1.85E-33 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CO689_RS03155 51958b5e747851bbd559f5d5e3a50082 102 Hamap MF_00508 30S ribosomal protein S10 [rpsJ]. 3 102 27.363 T 28-03-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CO689_RS03155 51958b5e747851bbd559f5d5e3a50082 102 Pfam PF00338 Ribosomal protein S10p/S20e 7 101 1.4E-35 T 28-03-2018 IPR027486 Ribosomal protein S10 domain CO689_RS03155 51958b5e747851bbd559f5d5e3a50082 102 ProSitePatterns PS00361 Ribosomal protein S10 signature. 29 44 - T 28-03-2018 IPR018268 Ribosomal protein S10, conserved site GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CO689_RS03155 51958b5e747851bbd559f5d5e3a50082 102 PRINTS PR00971 Ribosomal protein S10 family signature 40 55 1.2E-18 T 28-03-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CO689_RS03155 51958b5e747851bbd559f5d5e3a50082 102 PRINTS PR00971 Ribosomal protein S10 family signature 61 75 1.2E-18 T 28-03-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CO689_RS03155 51958b5e747851bbd559f5d5e3a50082 102 PRINTS PR00971 Ribosomal protein S10 family signature 5 18 1.2E-18 T 28-03-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CO689_RS03155 51958b5e747851bbd559f5d5e3a50082 102 TIGRFAM TIGR01049 rpsJ_bact: ribosomal protein uS10 4 101 8.2E-46 T 28-03-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CO689_RS03155 51958b5e747851bbd559f5d5e3a50082 102 Gene3D G3DSA:3.30.70.600 3 102 2.9E-35 T 28-03-2018 IPR027486 Ribosomal protein S10 domain CO689_RS03155 51958b5e747851bbd559f5d5e3a50082 102 SMART SM01403 7 101 1.6E-58 T 28-03-2018 IPR027486 Ribosomal protein S10 domain CO689_RS03155 51958b5e747851bbd559f5d5e3a50082 102 SUPERFAMILY SSF54999 5 102 1.16E-37 T 28-03-2018 IPR027486 Ribosomal protein S10 domain CO689_RS02085 2ce2839e0c63a61edc6533b9bad3cecd 539 ProSitePatterns PS00296 Chaperonins cpn60 signature. 403 414 - T 28-03-2018 IPR018370 Chaperonin Cpn60, conserved site GO:0005524|GO:0005737|GO:0006457 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 CO689_RS02085 2ce2839e0c63a61edc6533b9bad3cecd 539 SUPERFAMILY SSF54849 137 203 3.66E-26 T 28-03-2018 CO689_RS02085 2ce2839e0c63a61edc6533b9bad3cecd 539 SUPERFAMILY SSF52029 182 374 8.22E-82 T 28-03-2018 IPR027409 GroEL-like apical domain CO689_RS02085 2ce2839e0c63a61edc6533b9bad3cecd 539 Gene3D G3DSA:3.50.7.10 185 371 1.9E-93 T 28-03-2018 IPR027409 GroEL-like apical domain CO689_RS02085 2ce2839e0c63a61edc6533b9bad3cecd 539 Hamap MF_00600 60 kDa chaperonin [groL]. 1 538 40.65 T 28-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 CO689_RS02085 2ce2839e0c63a61edc6533b9bad3cecd 539 Gene3D G3DSA:1.10.560.10 372 513 7.1E-28 T 28-03-2018 IPR027413 GroEL-like equatorial domain CO689_RS02085 2ce2839e0c63a61edc6533b9bad3cecd 539 TIGRFAM TIGR02348 GroEL: chaperonin GroL 2 524 2.1E-248 T 28-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 CO689_RS02085 2ce2839e0c63a61edc6533b9bad3cecd 539 Pfam PF00118 TCP-1/cpn60 chaperonin family 22 520 2.9E-100 T 28-03-2018 IPR002423 Chaperonin Cpn60/TCP-1 family GO:0005524 CO689_RS02085 2ce2839e0c63a61edc6533b9bad3cecd 539 PRINTS PR00298 60kDa chaperonin signature 82 109 1.5E-72 T 28-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 CO689_RS02085 2ce2839e0c63a61edc6533b9bad3cecd 539 PRINTS PR00298 60kDa chaperonin signature 396 417 1.5E-72 T 28-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 CO689_RS02085 2ce2839e0c63a61edc6533b9bad3cecd 539 PRINTS PR00298 60kDa chaperonin signature 348 373 1.5E-72 T 28-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 CO689_RS02085 2ce2839e0c63a61edc6533b9bad3cecd 539 PRINTS PR00298 60kDa chaperonin signature 26 52 1.5E-72 T 28-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 CO689_RS02085 2ce2839e0c63a61edc6533b9bad3cecd 539 PRINTS PR00298 60kDa chaperonin signature 266 289 1.5E-72 T 28-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 CO689_RS02085 2ce2839e0c63a61edc6533b9bad3cecd 539 Gene3D G3DSA:1.10.560.10 1 184 9.9E-34 T 28-03-2018 IPR027413 GroEL-like equatorial domain CO689_RS02085 2ce2839e0c63a61edc6533b9bad3cecd 539 SUPERFAMILY SSF48592 404 518 1.25E-77 T 28-03-2018 CO689_RS02085 2ce2839e0c63a61edc6533b9bad3cecd 539 SUPERFAMILY SSF48592 5 133 1.25E-77 T 28-03-2018 CO689_RS13040 fe4b7e3a604710f2d110baac82ccd4a9 352 Pfam PF01321 Creatinase/Prolidase N-terminal domain 3 126 3.1E-23 T 28-03-2018 IPR000587 Creatinase, N-terminal GO:0016787 CO689_RS13040 fe4b7e3a604710f2d110baac82ccd4a9 352 SUPERFAMILY SSF53092 2 124 6.45E-24 T 28-03-2018 IPR028980 Creatinase/Aminopeptidase P, N-terminal CO689_RS13040 fe4b7e3a604710f2d110baac82ccd4a9 352 Pfam PF00557 Metallopeptidase family M24 134 336 1.6E-66 T 28-03-2018 IPR000994 Peptidase M24 CO689_RS13040 fe4b7e3a604710f2d110baac82ccd4a9 352 ProSitePatterns PS00491 Aminopeptidase P and proline dipeptidase signature. 282 294 - T 28-03-2018 IPR001131 Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site CO689_RS13040 fe4b7e3a604710f2d110baac82ccd4a9 352 Gene3D G3DSA:3.90.230.10 125 352 4.8E-79 T 28-03-2018 CO689_RS13040 fe4b7e3a604710f2d110baac82ccd4a9 352 SUPERFAMILY SSF55920 87 347 6.93E-81 T 28-03-2018 IPR000994 Peptidase M24 CO689_RS13040 fe4b7e3a604710f2d110baac82ccd4a9 352 Gene3D G3DSA:3.40.350.10 1 124 5.8E-27 T 28-03-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal CO689_RS12845 f8bf975fa0a4393dac49e7ea1ac8fa0d 318 Pfam PF14493 Helix-turn-helix domain 225 310 1.8E-16 T 28-03-2018 IPR029491 Helicase Helix-turn-helix domain Reactome: R-HSA-3108214|Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473 CO689_RS12845 f8bf975fa0a4393dac49e7ea1ac8fa0d 318 Gene3D G3DSA:1.10.10.10 131 261 4.1E-4 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS11970 38e1d126421ffd46517043b3b36bcad5 177 Pfam PF04309 Glycerol-3-phosphate responsive antiterminator 5 177 2.3E-61 T 28-03-2018 IPR006699 Glycerol-3-phosphate responsive antiterminator GO:0006355|GO:0009607 CO689_RS11970 38e1d126421ffd46517043b3b36bcad5 177 Gene3D G3DSA:3.20.20.400 2 177 8.4E-66 T 28-03-2018 CO689_RS11970 38e1d126421ffd46517043b3b36bcad5 177 SUPERFAMILY SSF110391 4 177 2.22E-56 T 28-03-2018 IPR006699 Glycerol-3-phosphate responsive antiterminator GO:0006355|GO:0009607 CO689_RS11970 38e1d126421ffd46517043b3b36bcad5 177 PIRSF PIRSF016897 1 177 1.3E-62 T 28-03-2018 IPR006699 Glycerol-3-phosphate responsive antiterminator GO:0006355|GO:0009607 CO689_RS10730 32e30ead02a812a95049e8c1d4fb0d43 86 Gene3D G3DSA:3.30.1280.10 1 80 5.7E-22 T 28-03-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 CO689_RS10730 32e30ead02a812a95049e8c1d4fb0d43 86 TIGRFAM TIGR00302 TIGR00302: phosphoribosylformylglycinamidine synthase, purS protein 4 79 2.0E-21 T 28-03-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 CO689_RS10730 32e30ead02a812a95049e8c1d4fb0d43 86 ProDom PD010362 PHOSPHORIBOSYLFORMYLGLYCINAMIDINE PURS SYNTHETASE SYNTHASE COMPONENT SYNTHASE LIGASE FGAM UPF0062 I 10 81 8.0E-34 T 28-03-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 CO689_RS10730 32e30ead02a812a95049e8c1d4fb0d43 86 SUPERFAMILY SSF82697 2 81 8.37E-22 T 28-03-2018 CO689_RS10730 32e30ead02a812a95049e8c1d4fb0d43 86 Pfam PF02700 Phosphoribosylformylglycinamidine (FGAM) synthase 4 79 1.7E-24 T 28-03-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 CO689_RS10730 32e30ead02a812a95049e8c1d4fb0d43 86 Hamap MF_01926 Phosphoribosylformylglycinamidine synthase subunit PurS [purS]. 2 79 18.215 T 28-03-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 CO689_RS08590 99c6e2ba5b02c26d28528b1e9553c5c1 264 SMART SM00257 89 132 2.4E-15 T 28-03-2018 IPR018392 LysM domain CO689_RS08590 99c6e2ba5b02c26d28528b1e9553c5c1 264 SMART SM00257 28 71 8.0E-15 T 28-03-2018 IPR018392 LysM domain CO689_RS08590 99c6e2ba5b02c26d28528b1e9553c5c1 264 SUPERFAMILY SSF54106 27 70 1.44E-11 T 28-03-2018 IPR018392 LysM domain CO689_RS08590 99c6e2ba5b02c26d28528b1e9553c5c1 264 Pfam PF01476 LysM domain 90 131 9.3E-14 T 28-03-2018 IPR018392 LysM domain CO689_RS08590 99c6e2ba5b02c26d28528b1e9553c5c1 264 Pfam PF01476 LysM domain 29 70 3.6E-14 T 28-03-2018 IPR018392 LysM domain CO689_RS08590 99c6e2ba5b02c26d28528b1e9553c5c1 264 SUPERFAMILY SSF54106 89 131 2.35E-10 T 28-03-2018 IPR018392 LysM domain CO689_RS08590 99c6e2ba5b02c26d28528b1e9553c5c1 264 Gene3D G3DSA:3.10.350.10 22 82 1.0E-16 T 28-03-2018 CO689_RS08590 99c6e2ba5b02c26d28528b1e9553c5c1 264 Gene3D G3DSA:3.10.350.10 83 156 4.6E-15 T 28-03-2018 CO689_RS08590 99c6e2ba5b02c26d28528b1e9553c5c1 264 SUPERFAMILY SSF54001 155 263 2.26E-19 T 28-03-2018 CO689_RS08590 99c6e2ba5b02c26d28528b1e9553c5c1 264 Pfam PF05257 CHAP domain 158 239 1.9E-13 T 28-03-2018 IPR007921 CHAP domain CO689_RS03225 e3ca9c3b0dba371dab352b2ffc113efe 417 SUPERFAMILY SSF55729 1 153 8.48E-36 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CO689_RS03225 e3ca9c3b0dba371dab352b2ffc113efe 417 Gene3D G3DSA:3.40.630.30 158 376 1.5E-31 T 28-03-2018 CO689_RS03225 e3ca9c3b0dba371dab352b2ffc113efe 417 Pfam PF02388 FemAB family 6 399 1.5E-79 T 28-03-2018 IPR003447 FemABX peptidyl transferase GO:0016755|GO:0044038 CO689_RS03225 e3ca9c3b0dba371dab352b2ffc113efe 417 SUPERFAMILY SSF55729 156 235 1.17E-28 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CO689_RS03225 e3ca9c3b0dba371dab352b2ffc113efe 417 SUPERFAMILY SSF55729 297 394 1.17E-28 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CO689_RS03225 e3ca9c3b0dba371dab352b2ffc113efe 417 Gene3D G3DSA:3.40.630.30 1 157 7.1E-39 T 28-03-2018 CO689_RS07235 92c308a93dc213c9445b75c376f1d37a 196 Gene3D G3DSA:3.40.50.2020 3 188 1.2E-21 T 28-03-2018 CO689_RS07235 92c308a93dc213c9445b75c376f1d37a 196 Hamap MF_01184 Xanthine phosphoribosyltransferase [xpt]. 1 189 39.306 T 28-03-2018 IPR010079 Xanthine phosphoribosyltransferase GO:0016763|GO:0043101|GO:0046110 KEGG: 00230+2.4.2.22 CO689_RS07235 92c308a93dc213c9445b75c376f1d37a 196 SUPERFAMILY SSF53271 2 186 1.2E-40 T 28-03-2018 IPR029057 Phosphoribosyltransferase-like CO689_RS07235 92c308a93dc213c9445b75c376f1d37a 196 TIGRFAM TIGR01744 XPRTase: xanthine phosphoribosyltransferase 2 191 1.4E-91 T 28-03-2018 IPR010079 Xanthine phosphoribosyltransferase GO:0016763|GO:0043101|GO:0046110 KEGG: 00230+2.4.2.22 CO689_RS07235 92c308a93dc213c9445b75c376f1d37a 196 Pfam PF00156 Phosphoribosyl transferase domain 47 162 6.6E-8 T 28-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 CO689_RS12015 bdeb52f5d23fda170e757283b0cbd4b0 417 Gene3D G3DSA:3.40.50.300 15 254 5.1E-14 T 28-03-2018 CO689_RS12015 bdeb52f5d23fda170e757283b0cbd4b0 417 SUPERFAMILY SSF52540 205 372 1.41E-33 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CO689_RS12015 bdeb52f5d23fda170e757283b0cbd4b0 417 Hamap MF_00900 GTPase HflX [hflX]. 35 391 43.067 T 28-03-2018 IPR016496 GTPase HflX GO:0005525 CO689_RS12015 bdeb52f5d23fda170e757283b0cbd4b0 417 Gene3D G3DSA:3.40.50.300 255 381 4.9E-14 T 28-03-2018 CO689_RS12015 bdeb52f5d23fda170e757283b0cbd4b0 417 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 274 292 1.6E-6 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CO689_RS12015 bdeb52f5d23fda170e757283b0cbd4b0 417 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 207 227 1.6E-6 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CO689_RS12015 bdeb52f5d23fda170e757283b0cbd4b0 417 PIRSF PIRSF006809 7 417 2.0E-140 T 28-03-2018 IPR016496 GTPase HflX GO:0005525 CO689_RS12015 bdeb52f5d23fda170e757283b0cbd4b0 417 Pfam PF13167 GTP-binding GTPase N-terminal 33 119 1.6E-26 T 28-03-2018 IPR025121 GTPase HflX, N-terminal CO689_RS12015 bdeb52f5d23fda170e757283b0cbd4b0 417 Pfam PF01926 50S ribosome-binding GTPase 206 325 3.2E-18 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CO689_RS12015 bdeb52f5d23fda170e757283b0cbd4b0 417 TIGRFAM TIGR03156 GTP_HflX: GTP-binding protein HflX 15 360 9.3E-135 T 28-03-2018 IPR016496 GTPase HflX GO:0005525 CO689_RS12015 bdeb52f5d23fda170e757283b0cbd4b0 417 Pfam PF16360 GTP-binding GTPase Middle Region 121 199 2.7E-31 T 28-03-2018 IPR032305 GTP-binding protein, middle domain CO689_RS09470 7b70f26c9bae011c541ab3ac2d59cfb3 341 Gene3D G3DSA:3.40.50.300 1 255 1.1E-76 T 28-03-2018 CO689_RS09470 7b70f26c9bae011c541ab3ac2d59cfb3 341 SMART SM00930 262 338 2.7E-16 T 28-03-2018 IPR018449 NIL domain CO689_RS09470 7b70f26c9bae011c541ab3ac2d59cfb3 341 Pfam PF00005 ABC transporter 22 169 1.4E-33 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CO689_RS09470 7b70f26c9bae011c541ab3ac2d59cfb3 341 Pfam PF09383 NIL domain 265 337 4.0E-15 T 28-03-2018 IPR018449 NIL domain CO689_RS09470 7b70f26c9bae011c541ab3ac2d59cfb3 341 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CO689_RS09470 7b70f26c9bae011c541ab3ac2d59cfb3 341 Gene3D G3DSA:3.30.70.260 256 340 6.9E-19 T 28-03-2018 CO689_RS09470 7b70f26c9bae011c541ab3ac2d59cfb3 341 SMART SM00382 30 218 8.5E-15 T 28-03-2018 IPR003593 AAA+ ATPase domain CO689_RS09470 7b70f26c9bae011c541ab3ac2d59cfb3 341 SUPERFAMILY SSF55021 249 340 2.86E-20 T 28-03-2018 CO689_RS09470 7b70f26c9bae011c541ab3ac2d59cfb3 341 SUPERFAMILY SSF52540 1 240 1.25E-82 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CO689_RS08415 f533e0483878f9278e1963d75e279d2a 310 SUPERFAMILY SSF53807 12 309 2.35E-80 T 28-03-2018 CO689_RS08415 f533e0483878f9278e1963d75e279d2a 310 PRINTS PR00691 Adhesin B signature 58 76 3.1E-75 T 28-03-2018 IPR006129 Adhesin B GO:0007155 CO689_RS08415 f533e0483878f9278e1963d75e279d2a 310 PRINTS PR00691 Adhesin B signature 245 262 3.1E-75 T 28-03-2018 IPR006129 Adhesin B GO:0007155 CO689_RS08415 f533e0483878f9278e1963d75e279d2a 310 PRINTS PR00691 Adhesin B signature 267 285 3.1E-75 T 28-03-2018 IPR006129 Adhesin B GO:0007155 CO689_RS08415 f533e0483878f9278e1963d75e279d2a 310 PRINTS PR00691 Adhesin B signature 222 240 3.1E-75 T 28-03-2018 IPR006129 Adhesin B GO:0007155 CO689_RS08415 f533e0483878f9278e1963d75e279d2a 310 PRINTS PR00691 Adhesin B signature 33 54 3.1E-75 T 28-03-2018 IPR006129 Adhesin B GO:0007155 CO689_RS08415 f533e0483878f9278e1963d75e279d2a 310 PRINTS PR00691 Adhesin B signature 196 213 3.1E-75 T 28-03-2018 IPR006129 Adhesin B GO:0007155 CO689_RS08415 f533e0483878f9278e1963d75e279d2a 310 PRINTS PR00691 Adhesin B signature 138 157 3.1E-75 T 28-03-2018 IPR006129 Adhesin B GO:0007155 CO689_RS08415 f533e0483878f9278e1963d75e279d2a 310 PRINTS PR00691 Adhesin B signature 288 306 3.1E-75 T 28-03-2018 IPR006129 Adhesin B GO:0007155 CO689_RS08415 f533e0483878f9278e1963d75e279d2a 310 PRINTS PR00691 Adhesin B signature 77 96 3.1E-75 T 28-03-2018 IPR006129 Adhesin B GO:0007155 CO689_RS08415 f533e0483878f9278e1963d75e279d2a 310 Gene3D G3DSA:3.40.50.1980 22 188 4.0E-43 T 28-03-2018 CO689_RS08415 f533e0483878f9278e1963d75e279d2a 310 Gene3D G3DSA:3.40.50.1980 189 310 4.8E-31 T 28-03-2018 CO689_RS08415 f533e0483878f9278e1963d75e279d2a 310 Pfam PF01297 Zinc-uptake complex component A periplasmic 36 306 3.8E-70 T 28-03-2018 IPR006127 Periplasmic solute binding protein, ZnuA-like GO:0030001|GO:0046872 CO689_RS08415 f533e0483878f9278e1963d75e279d2a 310 PRINTS PR00690 Adhesin family signature 196 217 1.3E-48 T 28-03-2018 IPR006128 Adhesion lipoprotein GO:0007155 CO689_RS08415 f533e0483878f9278e1963d75e279d2a 310 PRINTS PR00690 Adhesin family signature 77 94 1.3E-48 T 28-03-2018 IPR006128 Adhesion lipoprotein GO:0007155 CO689_RS08415 f533e0483878f9278e1963d75e279d2a 310 PRINTS PR00690 Adhesin family signature 64 77 1.3E-48 T 28-03-2018 IPR006128 Adhesion lipoprotein GO:0007155 CO689_RS08415 f533e0483878f9278e1963d75e279d2a 310 PRINTS PR00690 Adhesin family signature 275 294 1.3E-48 T 28-03-2018 IPR006128 Adhesion lipoprotein GO:0007155 CO689_RS08415 f533e0483878f9278e1963d75e279d2a 310 PRINTS PR00690 Adhesin family signature 33 51 1.3E-48 T 28-03-2018 IPR006128 Adhesion lipoprotein GO:0007155 CO689_RS08415 f533e0483878f9278e1963d75e279d2a 310 PRINTS PR00690 Adhesin family signature 249 267 1.3E-48 T 28-03-2018 IPR006128 Adhesion lipoprotein GO:0007155 CO689_RS12475 58d0517ddadb010e3e199959e46b97cd 358 Pfam PF01168 Alanine racemase, N-terminal domain 15 224 1.4E-37 T 28-03-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CO689_RS12475 58d0517ddadb010e3e199959e46b97cd 358 SUPERFAMILY SSF51419 10 227 5.23E-35 T 28-03-2018 IPR029066 PLP-binding barrel CO689_RS12475 58d0517ddadb010e3e199959e46b97cd 358 Hamap MF_01201 Alanine racemase. 1 358 19.013 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CO689_RS12475 58d0517ddadb010e3e199959e46b97cd 358 SUPERFAMILY SSF50621 231 350 5.93E-20 T 28-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 CO689_RS12475 58d0517ddadb010e3e199959e46b97cd 358 PRINTS PR00992 Alanine racemase signature 58 76 1.5E-19 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CO689_RS12475 58d0517ddadb010e3e199959e46b97cd 358 PRINTS PR00992 Alanine racemase signature 151 162 1.5E-19 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CO689_RS12475 58d0517ddadb010e3e199959e46b97cd 358 PRINTS PR00992 Alanine racemase signature 270 285 1.5E-19 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CO689_RS12475 58d0517ddadb010e3e199959e46b97cd 358 PRINTS PR00992 Alanine racemase signature 22 38 1.5E-19 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CO689_RS12475 58d0517ddadb010e3e199959e46b97cd 358 PRINTS PR00992 Alanine racemase signature 290 307 1.5E-19 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CO689_RS12475 58d0517ddadb010e3e199959e46b97cd 358 PRINTS PR00992 Alanine racemase signature 113 125 1.5E-19 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CO689_RS12475 58d0517ddadb010e3e199959e46b97cd 358 PRINTS PR00992 Alanine racemase signature 197 224 1.5E-19 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CO689_RS12475 58d0517ddadb010e3e199959e46b97cd 358 Pfam PF00842 Alanine racemase, C-terminal domain 237 333 2.7E-17 T 28-03-2018 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CO689_RS12475 58d0517ddadb010e3e199959e46b97cd 358 Gene3D G3DSA:3.20.20.10 6 222 8.6E-24 T 28-03-2018 IPR029066 PLP-binding barrel CO689_RS12475 58d0517ddadb010e3e199959e46b97cd 358 Gene3D G3DSA:2.40.37.10 223 352 4.3E-25 T 28-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 CO689_RS12475 58d0517ddadb010e3e199959e46b97cd 358 SMART SM01005 236 358 5.2E-16 T 28-03-2018 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CO689_RS06930 ed169d6fb834f3a2b3989f7a43f9fc00 232 SMART SM00448 3 113 5.4E-45 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CO689_RS06930 ed169d6fb834f3a2b3989f7a43f9fc00 232 SMART SM00862 152 228 3.6E-28 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CO689_RS06930 ed169d6fb834f3a2b3989f7a43f9fc00 232 Pfam PF00486 Transcriptional regulatory protein, C terminal 152 228 4.3E-28 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CO689_RS06930 ed169d6fb834f3a2b3989f7a43f9fc00 232 Gene3D G3DSA:3.40.50.2300 2 126 1.6E-37 T 28-03-2018 CO689_RS06930 ed169d6fb834f3a2b3989f7a43f9fc00 232 SUPERFAMILY SSF52172 3 126 8.11E-43 T 28-03-2018 IPR011006 CheY-like superfamily CO689_RS06930 ed169d6fb834f3a2b3989f7a43f9fc00 232 Gene3D G3DSA:1.10.10.10 127 232 1.9E-33 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS06930 ed169d6fb834f3a2b3989f7a43f9fc00 232 Pfam PF00072 Response regulator receiver domain 5 114 8.3E-30 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CO689_RS06930 ed169d6fb834f3a2b3989f7a43f9fc00 232 SUPERFAMILY SSF46894 128 228 5.1E-31 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CO689_RS04955 84457fdf83a435ab748234727fad594b 418 Gene3D G3DSA:1.20.1250.20 18 215 4.5E-25 T 28-03-2018 CO689_RS04955 84457fdf83a435ab748234727fad594b 418 Gene3D G3DSA:1.20.1250.20 224 418 1.0E-24 T 28-03-2018 CO689_RS04955 84457fdf83a435ab748234727fad594b 418 Pfam PF07690 Major Facilitator Superfamily 39 344 3.0E-27 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CO689_RS04955 84457fdf83a435ab748234727fad594b 418 SUPERFAMILY SSF103473 17 414 5.62E-52 T 28-03-2018 IPR020846 Major facilitator superfamily domain CO689_RS11205 39e778cdbedb48f137dc7cc93192d5b6 311 TIGRFAM TIGR00006 TIGR00006: 16S rRNA (cytosine(1402)-N(4))-methyltransferase 2 308 2.1E-121 T 28-03-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CO689_RS11205 39e778cdbedb48f137dc7cc93192d5b6 311 SUPERFAMILY SSF81799 113 214 8.5E-36 T 28-03-2018 IPR023397 S-adenosyl-L-methionine-dependent methyltransferase, MraW, recognition domain GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CO689_RS11205 39e778cdbedb48f137dc7cc93192d5b6 311 Gene3D G3DSA:3.40.50.150 3 112 1.1E-6 T 28-03-2018 CO689_RS11205 39e778cdbedb48f137dc7cc93192d5b6 311 Pfam PF01795 MraW methylase family 2 308 1.6E-132 T 28-03-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CO689_RS11205 39e778cdbedb48f137dc7cc93192d5b6 311 SUPERFAMILY SSF53335 214 308 1.37E-43 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CO689_RS11205 39e778cdbedb48f137dc7cc93192d5b6 311 SUPERFAMILY SSF53335 3 112 1.37E-43 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CO689_RS11205 39e778cdbedb48f137dc7cc93192d5b6 311 Hamap MF_01007 Ribosomal RNA small subunit methyltransferase H [rsmH]. 4 310 37.298 T 28-03-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CO689_RS11205 39e778cdbedb48f137dc7cc93192d5b6 311 PIRSF PIRSF004486 1 311 1.0E-104 T 28-03-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CO689_RS11205 39e778cdbedb48f137dc7cc93192d5b6 311 Gene3D G3DSA:1.10.150.170 113 216 8.4E-39 T 28-03-2018 IPR023397 S-adenosyl-L-methionine-dependent methyltransferase, MraW, recognition domain GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CO689_RS05385 3a6e713d45b7485cd8ffc738c125b98c 368 Gene3D G3DSA:3.40.1260.10 207 368 3.1E-50 T 28-03-2018 CO689_RS05385 3a6e713d45b7485cd8ffc738c125b98c 368 SMART SM00450 10 103 3.2E-19 T 28-03-2018 IPR001763 Rhodanese-like domain CO689_RS05385 3a6e713d45b7485cd8ffc738c125b98c 368 Pfam PF00581 Rhodanese-like domain 17 98 1.2E-15 T 28-03-2018 IPR001763 Rhodanese-like domain CO689_RS05385 3a6e713d45b7485cd8ffc738c125b98c 368 Pfam PF13686 DsrE/DsrF/DrsH-like family 214 367 5.8E-56 T 28-03-2018 IPR032836 DsrE2-like family CO689_RS05385 3a6e713d45b7485cd8ffc738c125b98c 368 Gene3D G3DSA:3.40.250.10 2 107 2.6E-23 T 28-03-2018 IPR001763 Rhodanese-like domain CO689_RS05385 3a6e713d45b7485cd8ffc738c125b98c 368 SUPERFAMILY SSF75169 216 260 8.83E-18 T 28-03-2018 IPR027396 DsrEFH-like CO689_RS05385 3a6e713d45b7485cd8ffc738c125b98c 368 SUPERFAMILY SSF75169 310 356 8.83E-18 T 28-03-2018 IPR027396 DsrEFH-like CO689_RS05385 3a6e713d45b7485cd8ffc738c125b98c 368 SUPERFAMILY SSF64307 129 199 2.62E-18 T 28-03-2018 IPR001455 TusA-like domain CO689_RS05385 3a6e713d45b7485cd8ffc738c125b98c 368 SUPERFAMILY SSF52821 12 100 7.33E-25 T 28-03-2018 IPR001763 Rhodanese-like domain CO689_RS05385 3a6e713d45b7485cd8ffc738c125b98c 368 Gene3D G3DSA:3.30.110.40 108 200 2.1E-25 T 28-03-2018 IPR001455 TusA-like domain CO689_RS05385 3a6e713d45b7485cd8ffc738c125b98c 368 Pfam PF01206 Sulfurtransferase TusA 130 199 3.3E-17 T 28-03-2018 IPR001455 TusA-like domain CO689_RS05385 3a6e713d45b7485cd8ffc738c125b98c 368 ProSitePatterns PS01148 Uncharacterized protein family UPF0033 signature. 132 156 - T 28-03-2018 IPR001455 TusA-like domain CO689_RS12675 9d0b753d0870d09308cdc9b4e03d7853 109 Pfam PF05103 DivIVA protein 8 70 5.1E-11 T 28-03-2018 IPR007793 DivIVA family CO689_RS12675 9d0b753d0870d09308cdc9b4e03d7853 109 TIGRFAM TIGR03544 DivI1A_domain: DivIVA domain 8 42 2.5E-14 T 28-03-2018 IPR019933 DivIVA domain CO689_RS12675 9d0b753d0870d09308cdc9b4e03d7853 109 Gene3D G3DSA:1.20.5.170 19 76 2.0E-4 T 28-03-2018 CO689_RS12675 9d0b753d0870d09308cdc9b4e03d7853 109 PIRSF PIRSF029938 1 109 5.0E-38 T 28-03-2018 IPR011229 Cell cycle protein GpsB CO689_RS13130 df29c0a8a05502ad251eff3370e8cdfd 66 SUPERFAMILY SSF158379 5 63 1.7E-22 T 28-03-2018 IPR023164 YqgQ-like domain CO689_RS13130 df29c0a8a05502ad251eff3370e8cdfd 66 Pfam PF06014 Bacterial protein of unknown function (DUF910) 5 63 1.3E-24 T 28-03-2018 IPR009256 Protein of unknown function DUF910 CO689_RS13130 df29c0a8a05502ad251eff3370e8cdfd 66 Gene3D G3DSA:1.10.287.760 5 66 4.3E-25 T 28-03-2018 IPR023164 YqgQ-like domain CO689_RS03785 855247c98b167d96d7d7380ac63f391b 152 SMART SM00347 28 130 3.0E-9 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CO689_RS03785 855247c98b167d96d7d7380ac63f391b 152 Pfam PF12802 MarR family 36 89 8.5E-9 T 28-03-2018 CO689_RS03785 855247c98b167d96d7d7380ac63f391b 152 SUPERFAMILY SSF46785 9 147 4.27E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS03785 855247c98b167d96d7d7380ac63f391b 152 Gene3D G3DSA:1.10.10.10 1 151 5.2E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS06965 32088a73e5149acdc7fde40344934e4b 655 Pfam PF02272 DHHA1 domain 517 645 1.0E-11 T 28-03-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 CO689_RS06965 32088a73e5149acdc7fde40344934e4b 655 SUPERFAMILY SSF64182 336 640 7.06E-67 T 28-03-2018 CO689_RS06965 32088a73e5149acdc7fde40344934e4b 655 Gene3D G3DSA:3.90.1640.10 315 533 6.1E-44 T 28-03-2018 CO689_RS06965 32088a73e5149acdc7fde40344934e4b 655 SMART SM00267 126 297 6.4E-5 T 28-03-2018 IPR000160 GGDEF domain CO689_RS06965 32088a73e5149acdc7fde40344934e4b 655 Gene3D G3DSA:3.30.70.270 124 298 3.7E-4 T 28-03-2018 CO689_RS06965 32088a73e5149acdc7fde40344934e4b 655 PIRSF PIRSF026583 1 655 1.5E-256 T 28-03-2018 IPR014528 Cyclic-di-AMP phosphodiesterase GdpP/PdeA CO689_RS06965 32088a73e5149acdc7fde40344934e4b 655 Pfam PF01368 DHH family 337 494 7.9E-22 T 28-03-2018 IPR001667 DDH domain KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 CO689_RS01720 d58c74261a6029b1b09914a7209974ba 192 Gene3D G3DSA:3.40.1050.10 1 189 6.2E-33 T 28-03-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 CO689_RS01720 d58c74261a6029b1b09914a7209974ba 192 Pfam PF00484 Carbonic anhydrase 33 178 3.3E-17 T 28-03-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 CO689_RS01720 d58c74261a6029b1b09914a7209974ba 192 SUPERFAMILY SSF53056 3 183 7.46E-39 T 28-03-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 CO689_RS01720 d58c74261a6029b1b09914a7209974ba 192 SMART SM00947 26 182 2.0E-24 T 28-03-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 CO689_RS06770 74212e1c7dc203998b911f9182f6c07d 73 Pfam PF13673 Acetyltransferase (GNAT) domain 1 59 3.5E-9 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CO689_RS06770 74212e1c7dc203998b911f9182f6c07d 73 SUPERFAMILY SSF55729 1 69 2.7E-14 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CO689_RS06770 74212e1c7dc203998b911f9182f6c07d 73 Gene3D G3DSA:3.40.630.30 1 73 2.6E-14 T 28-03-2018 CO689_RS05045 5cb82a972d85ae8c9a37575c8b129e8c 432 SUPERFAMILY SSF53448 1 214 2.13E-39 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CO689_RS05045 5cb82a972d85ae8c9a37575c8b129e8c 432 Gene3D G3DSA:3.90.550.10 1 296 5.7E-36 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CO689_RS05045 5cb82a972d85ae8c9a37575c8b129e8c 432 Pfam PF00535 Glycosyl transferase family 2 3 148 6.3E-26 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CO689_RS07740 f86866cd2743e56d1216c82169b4f048 511 Pfam PF01943 Polysaccharide biosynthesis protein 9 294 1.9E-23 T 28-03-2018 IPR002797 Polysaccharide biosynthesis protein GO:0016020 CO689_RS07740 f86866cd2743e56d1216c82169b4f048 511 Pfam PF14667 Polysaccharide biosynthesis C-terminal domain 346 487 3.1E-20 T 28-03-2018 IPR029303 Polysaccharide biosynthesis protein, C-terminal domain CO689_RS03990 cb0975916c4d3b79dab6a8df29a13b50 238 Gene3D G3DSA:3.40.50.1400 119 237 3.8E-12 T 28-03-2018 CO689_RS03990 cb0975916c4d3b79dab6a8df29a13b50 238 Gene3D G3DSA:3.40.50.1400 2 118 4.6E-14 T 28-03-2018 CO689_RS03990 cb0975916c4d3b79dab6a8df29a13b50 238 Pfam PF01903 CbiX 9 112 2.3E-20 T 28-03-2018 IPR002762 Cobalamin (vitamin B12) biosynthesis CbiX GO:0009236|GO:0016852 KEGG: 00860+4.99.1.3|MetaCyc: PWY-7377 CO689_RS03990 cb0975916c4d3b79dab6a8df29a13b50 238 SUPERFAMILY SSF53800 5 234 3.64E-26 T 28-03-2018 CO689_RS10745 7920748b84317f5996e97b9ed83ecdfe 473 SUPERFAMILY SSF56235 11 232 1.12E-61 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CO689_RS10745 7920748b84317f5996e97b9ed83ecdfe 473 TIGRFAM TIGR01134 purF: amidophosphoribosyltransferase 11 454 5.8E-151 T 28-03-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 CO689_RS10745 7920748b84317f5996e97b9ed83ecdfe 473 Gene3D G3DSA:3.40.50.2020 244 438 1.3E-31 T 28-03-2018 CO689_RS10745 7920748b84317f5996e97b9ed83ecdfe 473 Pfam PF00156 Phosphoribosyl transferase domain 267 382 3.5E-8 T 28-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 CO689_RS10745 7920748b84317f5996e97b9ed83ecdfe 473 Pfam PF13522 Glutamine amidotransferase domain 72 204 6.1E-21 T 28-03-2018 CO689_RS10745 7920748b84317f5996e97b9ed83ecdfe 473 PIRSF PIRSF000485 7 469 2.0E-167 T 28-03-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 CO689_RS10745 7920748b84317f5996e97b9ed83ecdfe 473 Hamap MF_01931 Amidophosphoribosyltransferase [purF]. 10 453 43.465 T 28-03-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 CO689_RS10745 7920748b84317f5996e97b9ed83ecdfe 473 Gene3D G3DSA:3.60.20.10 11 243 1.7E-51 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CO689_RS10745 7920748b84317f5996e97b9ed83ecdfe 473 SUPERFAMILY SSF53271 247 467 3.36E-67 T 28-03-2018 IPR029057 Phosphoribosyltransferase-like CO689_RS11795 25ddee3f016b0289523773f8e33d3ad8 324 Gene3D G3DSA:2.40.30.30 181 316 3.2E-41 T 28-03-2018 IPR023465 Riboflavin kinase domain GO:0008531|GO:0009231 Reactome: R-HSA-196843 CO689_RS11795 25ddee3f016b0289523773f8e33d3ad8 324 Pfam PF01687 Riboflavin kinase 185 311 8.6E-37 T 28-03-2018 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 Reactome: R-HSA-196843 CO689_RS11795 25ddee3f016b0289523773f8e33d3ad8 324 Pfam PF06574 FAD synthetase 16 167 6.0E-49 T 28-03-2018 IPR015864 FAD synthetase GO:0003919|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7863 CO689_RS11795 25ddee3f016b0289523773f8e33d3ad8 324 Gene3D G3DSA:3.40.50.620 1 180 7.0E-38 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CO689_RS11795 25ddee3f016b0289523773f8e33d3ad8 324 PIRSF PIRSF004491 1 318 2.5E-101 T 28-03-2018 IPR002606 Riboflavin kinase, bacterial GO:0003919|GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7863 CO689_RS11795 25ddee3f016b0289523773f8e33d3ad8 324 SMART SM00904 184 313 3.4E-59 T 28-03-2018 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 Reactome: R-HSA-196843 CO689_RS11795 25ddee3f016b0289523773f8e33d3ad8 324 SUPERFAMILY SSF82114 174 313 3.49E-44 T 28-03-2018 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 Reactome: R-HSA-196843 CO689_RS11795 25ddee3f016b0289523773f8e33d3ad8 324 SUPERFAMILY SSF52374 20 177 2.31E-26 T 28-03-2018 CO689_RS11795 25ddee3f016b0289523773f8e33d3ad8 324 TIGRFAM TIGR00083 ribF: riboflavin biosynthesis protein RibF 21 312 8.9E-90 T 28-03-2018 IPR002606 Riboflavin kinase, bacterial GO:0003919|GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7863 CO689_RS09045 0c9a40387eba8a7bb44b557346a14a45 379 Gene3D G3DSA:3.90.1510.10 43 270 3.6E-39 T 28-03-2018 IPR018193 Glycerate kinase, flavodoxin-like domain GO:0008887|GO:0031388 CO689_RS09045 0c9a40387eba8a7bb44b557346a14a45 379 SUPERFAMILY SSF110738 1 366 3.53E-81 T 28-03-2018 IPR004381 Glycerate kinase GO:0008887|GO:0031388 CO689_RS09045 0c9a40387eba8a7bb44b557346a14a45 379 Pfam PF02595 Glycerate kinase family 3 341 3.4E-54 T 28-03-2018 IPR004381 Glycerate kinase GO:0008887|GO:0031388 CO689_RS09045 0c9a40387eba8a7bb44b557346a14a45 379 TIGRFAM TIGR00045 TIGR00045: glycerate kinase 2 340 1.9E-53 T 28-03-2018 IPR004381 Glycerate kinase GO:0008887|GO:0031388 CO689_RS02735 9dccfecbc73181a17345560f4c52c70d 268 Gene3D G3DSA:3.40.1700.10 115 242 2.8E-36 T 28-03-2018 IPR003390 DNA integrity scanning protein, DisA, N-terminal CO689_RS02735 9dccfecbc73181a17345560f4c52c70d 268 Pfam PF02457 DisA bacterial checkpoint controller nucleotide-binding 123 240 3.4E-44 T 28-03-2018 IPR003390 DNA integrity scanning protein, DisA, N-terminal CO689_RS02735 9dccfecbc73181a17345560f4c52c70d 268 SUPERFAMILY SSF143597 44 241 4.18E-67 T 28-03-2018 IPR003390 DNA integrity scanning protein, DisA, N-terminal CO689_RS02735 9dccfecbc73181a17345560f4c52c70d 268 TIGRFAM TIGR00159 TIGR00159: TIGR00159 family protein 8 257 5.3E-89 T 28-03-2018 IPR034701 Diadenylate cyclase CdaA GO:0004016|GO:0006171 CO689_RS02735 9dccfecbc73181a17345560f4c52c70d 268 Hamap MF_01499 Diadenylate cyclase [dacA]. 8 258 32.365 T 28-03-2018 IPR034701 Diadenylate cyclase CdaA GO:0004016|GO:0006171 CO689_RS02735 9dccfecbc73181a17345560f4c52c70d 268 PIRSF PIRSF004793 7 265 2.1E-89 T 28-03-2018 IPR014046 Diadenylate cyclase GO:0004016|GO:0006171 CO689_RS10285 3ecb94f7048d396e3c8ecbd2c1627981 256 Gene3D G3DSA:3.40.50.720 1 256 1.2E-45 T 28-03-2018 CO689_RS10285 3ecb94f7048d396e3c8ecbd2c1627981 256 SUPERFAMILY SSF51735 5 254 3.17E-65 T 28-03-2018 IPR016040 NAD(P)-binding domain CO689_RS10285 3ecb94f7048d396e3c8ecbd2c1627981 256 PIRSF PIRSF000094 1 256 2.0E-96 T 28-03-2018 IPR014358 Enoyl-[acyl-carrier-protein] reductase (NADH) GO:0004318|GO:0006633|GO:0055114 KEGG: 00061+1.3.1.9|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 CO689_RS10285 3ecb94f7048d396e3c8ecbd2c1627981 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 134 150 8.7E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CO689_RS10285 3ecb94f7048d396e3c8ecbd2c1627981 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 181 198 8.7E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CO689_RS10285 3ecb94f7048d396e3c8ecbd2c1627981 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 216 236 8.7E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CO689_RS10285 3ecb94f7048d396e3c8ecbd2c1627981 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 160 179 8.7E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CO689_RS10285 3ecb94f7048d396e3c8ecbd2c1627981 256 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 253 2.3E-83 T 28-03-2018 CO689_RS11580 f3f050f6f0bffd9931f38f3e133bf830 116 PRINTS PR00061 Ribosomal protein L19 signature 36 65 9.8E-43 T 28-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CO689_RS11580 f3f050f6f0bffd9931f38f3e133bf830 116 PRINTS PR00061 Ribosomal protein L19 signature 6 35 9.8E-43 T 28-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CO689_RS11580 f3f050f6f0bffd9931f38f3e133bf830 116 PRINTS PR00061 Ribosomal protein L19 signature 90 115 9.8E-43 T 28-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CO689_RS11580 f3f050f6f0bffd9931f38f3e133bf830 116 ProSitePatterns PS01015 Ribosomal protein L19 signature. 88 103 - T 28-03-2018 IPR018257 Ribosomal protein L19, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CO689_RS11580 f3f050f6f0bffd9931f38f3e133bf830 116 PIRSF PIRSF002191 1 116 4.9E-52 T 28-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CO689_RS11580 f3f050f6f0bffd9931f38f3e133bf830 116 SUPERFAMILY SSF50104 3 115 1.91E-49 T 28-03-2018 IPR008991 Translation protein SH3-like domain CO689_RS11580 f3f050f6f0bffd9931f38f3e133bf830 116 Hamap MF_00402 50S ribosomal protein L19 [rplS]. 4 116 33.352 T 28-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CO689_RS11580 f3f050f6f0bffd9931f38f3e133bf830 116 TIGRFAM TIGR01024 rplS_bact: ribosomal protein bL19 5 115 3.4E-51 T 28-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CO689_RS11580 f3f050f6f0bffd9931f38f3e133bf830 116 Pfam PF01245 Ribosomal protein L19 6 114 1.1E-53 T 28-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CO689_RS01055 c8adfab44f697e7bf1028910caeabb1e 231 SUPERFAMILY SSF55120 61 226 7.67E-42 T 28-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 CO689_RS01055 c8adfab44f697e7bf1028910caeabb1e 231 ProSitePatterns PS01149 Rsu family of pseudouridine synthase signature. 99 113 - T 28-03-2018 IPR018496 Pseudouridine synthase, RsuA/RluB/E/F, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0016866 CO689_RS01055 c8adfab44f697e7bf1028910caeabb1e 231 SUPERFAMILY SSF55174 1 58 1.43E-13 T 28-03-2018 CO689_RS01055 c8adfab44f697e7bf1028910caeabb1e 231 Pfam PF01479 S4 domain 1 45 9.4E-10 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CO689_RS01055 c8adfab44f697e7bf1028910caeabb1e 231 Gene3D G3DSA:3.30.70.1560 143 208 2.7E-22 T 28-03-2018 CO689_RS01055 c8adfab44f697e7bf1028910caeabb1e 231 Gene3D G3DSA:3.10.290.10 1 55 3.1E-15 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CO689_RS01055 c8adfab44f697e7bf1028910caeabb1e 231 TIGRFAM TIGR00093 TIGR00093: pseudouridine synthase 66 223 2.7E-45 T 28-03-2018 IPR000748 Pseudouridine synthase, RsuA/RluB/E/F GO:0001522|GO:0003723|GO:0009451|GO:0016866 CO689_RS01055 c8adfab44f697e7bf1028910caeabb1e 231 Pfam PF00849 RNA pseudouridylate synthase 62 191 1.4E-16 T 28-03-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 CO689_RS01055 c8adfab44f697e7bf1028910caeabb1e 231 Gene3D G3DSA:3.30.70.580 56 142 2.1E-16 T 28-03-2018 CO689_RS01055 c8adfab44f697e7bf1028910caeabb1e 231 SMART SM00363 1 56 5.5E-10 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CO689_RS11255 55672432433f5c44b3abf75698bdf040 200 Hamap MF_01197 Cell division protein SepF [sepF]. 1 192 19.657 T 28-03-2018 IPR023052 Cell division protein SepF GO:0090529 CO689_RS11255 55672432433f5c44b3abf75698bdf040 200 Pfam PF04472 Cell division protein SepF 114 184 5.1E-28 T 28-03-2018 IPR007561 Cell division protein SepF/SepF-related GO:0090529 CO689_RS12435 d1037683b6f398b046244f8771e3b1ad 303 SUPERFAMILY SSF46785 252 299 3.33E-5 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS12435 d1037683b6f398b046244f8771e3b1ad 303 Gene3D G3DSA:1.10.10.10 232 289 4.6E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS12435 d1037683b6f398b046244f8771e3b1ad 303 Gene3D G3DSA:2.40.50.140 150 231 7.7E-4 T 28-03-2018 CO689_RS12435 d1037683b6f398b046244f8771e3b1ad 303 Pfam PF13509 S1 domain 9 70 4.2E-8 T 28-03-2018 CO689_RS12435 d1037683b6f398b046244f8771e3b1ad 303 PIRSF PIRSF012524 5 291 8.1E-105 T 28-03-2018 IPR014464 Conserved virulence factor B CO689_RS05620 d48a5212d1231c878726eae1de5d13af 310 SUPERFAMILY SSF53633 1 308 6.68E-80 T 28-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase CO689_RS05620 d48a5212d1231c878726eae1de5d13af 310 Gene3D G3DSA:3.40.1160.10 1 310 3.5E-55 T 28-03-2018 CO689_RS05620 d48a5212d1231c878726eae1de5d13af 310 PRINTS PR01469 Bacterial carbamate kinase signature 155 174 2.4E-61 T 28-03-2018 CO689_RS05620 d48a5212d1231c878726eae1de5d13af 310 PRINTS PR01469 Bacterial carbamate kinase signature 178 196 2.4E-61 T 28-03-2018 CO689_RS05620 d48a5212d1231c878726eae1de5d13af 310 PRINTS PR01469 Bacterial carbamate kinase signature 106 125 2.4E-61 T 28-03-2018 CO689_RS05620 d48a5212d1231c878726eae1de5d13af 310 PRINTS PR01469 Bacterial carbamate kinase signature 209 224 2.4E-61 T 28-03-2018 CO689_RS05620 d48a5212d1231c878726eae1de5d13af 310 PRINTS PR01469 Bacterial carbamate kinase signature 264 279 2.4E-61 T 28-03-2018 CO689_RS05620 d48a5212d1231c878726eae1de5d13af 310 PRINTS PR01469 Bacterial carbamate kinase signature 38 57 2.4E-61 T 28-03-2018 CO689_RS05620 d48a5212d1231c878726eae1de5d13af 310 PRINTS PR01469 Bacterial carbamate kinase signature 71 89 2.4E-61 T 28-03-2018 CO689_RS05620 d48a5212d1231c878726eae1de5d13af 310 Pfam PF00696 Amino acid kinase family 3 283 7.1E-27 T 28-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase CO689_RS05620 d48a5212d1231c878726eae1de5d13af 310 TIGRFAM TIGR00746 arcC: carbamate kinase 3 310 1.3E-115 T 28-03-2018 IPR003964 Carbamate kinase GO:0006525|GO:0008804 KEGG: 00220+2.7.2.2|KEGG: 00230+2.7.2.2|KEGG: 00910+2.7.2.2 CO689_RS05620 d48a5212d1231c878726eae1de5d13af 310 PIRSF PIRSF000723 1 310 1.1E-125 T 28-03-2018 IPR003964 Carbamate kinase GO:0006525|GO:0008804 KEGG: 00220+2.7.2.2|KEGG: 00230+2.7.2.2|KEGG: 00910+2.7.2.2 CO689_RS13070 10e6ebb5ddc86696654b0a1a22442e16 449 Pfam PF02347 Glycine cleavage system P-protein 3 441 7.5E-155 T 28-03-2018 IPR020581 Glycine cleavage system P protein GO:0004375|GO:0006546|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 CO689_RS13070 10e6ebb5ddc86696654b0a1a22442e16 449 Gene3D G3DSA:3.90.1150.10 338 448 9.1E-28 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CO689_RS13070 10e6ebb5ddc86696654b0a1a22442e16 449 SUPERFAMILY SSF53383 3 443 2.45E-115 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CO689_RS13070 10e6ebb5ddc86696654b0a1a22442e16 449 PIRSF PIRSF006815 3 447 6.1E-183 T 28-03-2018 IPR023010 Probable glycine dehydrogenase (decarboxylating) subunit 1 GO:0004375|GO:0009116 KEGG: 00260+1.4.4.2 CO689_RS13070 10e6ebb5ddc86696654b0a1a22442e16 449 Hamap MF_00712 Probable glycine dehydrogenase (decarboxylating) subunit 1 [gcvPA]. 3 446 49.263 T 28-03-2018 IPR023010 Probable glycine dehydrogenase (decarboxylating) subunit 1 GO:0004375|GO:0009116 KEGG: 00260+1.4.4.2 CO689_RS13070 10e6ebb5ddc86696654b0a1a22442e16 449 Gene3D G3DSA:3.40.640.10 84 337 1.2E-46 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CO689_RS09395 dff69903fc2f853a023723bb8b777f37 67 ProSitePatterns PS00352 'Cold-shock' domain signature. 15 33 - T 28-03-2018 IPR019844 Cold-shock conserved site CO689_RS09395 dff69903fc2f853a023723bb8b777f37 67 Pfam PF00313 'Cold-shock' DNA-binding domain 3 65 2.1E-31 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CO689_RS09395 dff69903fc2f853a023723bb8b777f37 67 SMART SM00357 3 66 4.0E-30 T 28-03-2018 IPR011129 Cold shock domain GO:0003676 CO689_RS09395 dff69903fc2f853a023723bb8b777f37 67 PRINTS PR00050 Cold shock protein signature 39 57 4.1E-20 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CO689_RS09395 dff69903fc2f853a023723bb8b777f37 67 PRINTS PR00050 Cold shock protein signature 24 33 4.1E-20 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CO689_RS09395 dff69903fc2f853a023723bb8b777f37 67 PRINTS PR00050 Cold shock protein signature 4 19 4.1E-20 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CO689_RS09395 dff69903fc2f853a023723bb8b777f37 67 SUPERFAMILY SSF50249 1 65 3.43E-25 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CO689_RS09395 dff69903fc2f853a023723bb8b777f37 67 PIRSF PIRSF002599 1 67 1.6E-24 T 28-03-2018 IPR012156 Cold shock, CspA GO:0003676 CO689_RS09395 dff69903fc2f853a023723bb8b777f37 67 Gene3D G3DSA:2.40.50.140 1 66 1.2E-27 T 28-03-2018 CO689_RS01865 4717ea75a5108b4e8b557799c991b0d8 268 SUPERFAMILY SSF55021 170 265 5.64E-20 T 28-03-2018 CO689_RS01865 4717ea75a5108b4e8b557799c991b0d8 268 Pfam PF00800 Prephenate dehydratase 4 176 2.3E-39 T 28-03-2018 IPR001086 Prephenate dehydratase GO:0004664|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 CO689_RS01865 4717ea75a5108b4e8b557799c991b0d8 268 SUPERFAMILY SSF53850 1 181 1.95E-46 T 28-03-2018 CO689_RS01865 4717ea75a5108b4e8b557799c991b0d8 268 Gene3D G3DSA:3.40.190.10 90 164 3.1E-10 T 28-03-2018 CO689_RS01865 4717ea75a5108b4e8b557799c991b0d8 268 Gene3D G3DSA:3.30.70.260 178 268 2.3E-18 T 28-03-2018 CO689_RS01865 4717ea75a5108b4e8b557799c991b0d8 268 Gene3D G3DSA:3.40.190.10 1 89 6.8E-21 T 28-03-2018 CO689_RS00935 87b8fb88fe603efc8a804d665ec4dd25 389 SUPERFAMILY SSF50156 281 386 1.22E-11 T 28-03-2018 IPR001478 PDZ domain GO:0005515 CO689_RS00935 87b8fb88fe603efc8a804d665ec4dd25 389 Gene3D G3DSA:2.40.10.10 189 295 1.2E-35 T 28-03-2018 CO689_RS00935 87b8fb88fe603efc8a804d665ec4dd25 389 Gene3D G3DSA:2.30.42.10 296 389 2.9E-15 T 28-03-2018 CO689_RS00935 87b8fb88fe603efc8a804d665ec4dd25 389 SUPERFAMILY SSF50494 73 293 3.38E-57 T 28-03-2018 IPR009003 Peptidase S1, PA clan CO689_RS00935 87b8fb88fe603efc8a804d665ec4dd25 389 PRINTS PR00834 HtrA/DegQ protease family signature 251 268 3.4E-37 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CO689_RS00935 87b8fb88fe603efc8a804d665ec4dd25 389 PRINTS PR00834 HtrA/DegQ protease family signature 188 212 3.4E-37 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CO689_RS00935 87b8fb88fe603efc8a804d665ec4dd25 389 PRINTS PR00834 HtrA/DegQ protease family signature 334 346 3.4E-37 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CO689_RS00935 87b8fb88fe603efc8a804d665ec4dd25 389 PRINTS PR00834 HtrA/DegQ protease family signature 229 246 3.4E-37 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CO689_RS00935 87b8fb88fe603efc8a804d665ec4dd25 389 PRINTS PR00834 HtrA/DegQ protease family signature 126 138 3.4E-37 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CO689_RS00935 87b8fb88fe603efc8a804d665ec4dd25 389 PRINTS PR00834 HtrA/DegQ protease family signature 147 167 3.4E-37 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CO689_RS00935 87b8fb88fe603efc8a804d665ec4dd25 389 Gene3D G3DSA:2.40.10.10 69 188 2.7E-31 T 28-03-2018 CO689_RS00935 87b8fb88fe603efc8a804d665ec4dd25 389 Pfam PF13365 Trypsin-like peptidase domain 114 258 4.1E-33 T 28-03-2018 CO689_RS00935 87b8fb88fe603efc8a804d665ec4dd25 389 Pfam PF13180 PDZ domain 323 386 5.0E-14 T 28-03-2018 IPR001478 PDZ domain GO:0005515 CO689_RS04270 713f79c676e4e76fa571b6cbf8305508 100 SUPERFAMILY SSF54909 1 92 7.6E-20 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel CO689_RS04270 713f79c676e4e76fa571b6cbf8305508 100 Gene3D G3DSA:3.30.70.100 1 100 4.2E-17 T 28-03-2018 CO689_RS04270 713f79c676e4e76fa571b6cbf8305508 100 Pfam PF03992 Antibiotic biosynthesis monooxygenase 1 74 8.2E-10 T 28-03-2018 IPR007138 Antibiotic biosynthesis monooxygenase domain CO689_RS06630 0ce0386aaa505abaac0111de4de17f44 382 PRINTS PR00344 Bacterial sensor protein C-terminal signature 370 382 4.4E-16 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CO689_RS06630 0ce0386aaa505abaac0111de4de17f44 382 PRINTS PR00344 Bacterial sensor protein C-terminal signature 333 343 4.4E-16 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CO689_RS06630 0ce0386aaa505abaac0111de4de17f44 382 PRINTS PR00344 Bacterial sensor protein C-terminal signature 315 329 4.4E-16 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CO689_RS06630 0ce0386aaa505abaac0111de4de17f44 382 PRINTS PR00344 Bacterial sensor protein C-terminal signature 346 364 4.4E-16 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CO689_RS06630 0ce0386aaa505abaac0111de4de17f44 382 SUPERFAMILY SSF55874 241 382 6.94E-31 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CO689_RS06630 0ce0386aaa505abaac0111de4de17f44 382 Gene3D G3DSA:1.10.287.130 164 234 2.8E-10 T 28-03-2018 CO689_RS06630 0ce0386aaa505abaac0111de4de17f44 382 Pfam PF00512 His Kinase A (phospho-acceptor) domain 174 236 1.9E-8 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CO689_RS06630 0ce0386aaa505abaac0111de4de17f44 382 SMART SM00388 173 240 7.4E-7 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CO689_RS06630 0ce0386aaa505abaac0111de4de17f44 382 Gene3D G3DSA:3.30.565.10 242 382 6.0E-34 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CO689_RS06630 0ce0386aaa505abaac0111de4de17f44 382 SMART SM00387 278 382 6.1E-19 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CO689_RS06630 0ce0386aaa505abaac0111de4de17f44 382 SUPERFAMILY SSF47384 164 233 3.73E-10 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CO689_RS06630 0ce0386aaa505abaac0111de4de17f44 382 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 282 382 1.3E-18 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CO689_RS04840 b00feb6f1673f0563a88ed5d6b577718 310 Gene3D G3DSA:3.40.50.720 2 174 4.7E-30 T 28-03-2018 CO689_RS04840 b00feb6f1673f0563a88ed5d6b577718 310 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 242 2.1E-62 T 28-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 CO689_RS04840 b00feb6f1673f0563a88ed5d6b577718 310 SUPERFAMILY SSF51735 1 309 2.11E-86 T 28-03-2018 IPR016040 NAD(P)-binding domain CO689_RS04840 b00feb6f1673f0563a88ed5d6b577718 310 Gene3D G3DSA:3.90.25.10 175 310 3.3E-38 T 28-03-2018 CO689_RS06895 ee7afb2c6109db3a152dbc0c95060a5e 909 Pfam PF00534 Glycosyl transferases group 1 741 887 2.3E-20 T 28-03-2018 IPR001296 Glycosyl transferase, family 1 CO689_RS06895 ee7afb2c6109db3a152dbc0c95060a5e 909 SUPERFAMILY SSF53756 452 600 2.13E-5 T 28-03-2018 CO689_RS06895 ee7afb2c6109db3a152dbc0c95060a5e 909 Pfam PF04464 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase 21 370 1.3E-58 T 28-03-2018 IPR007554 CDP-glycerol glycerophosphotransferase GO:0016020|GO:0047355 CO689_RS06895 ee7afb2c6109db3a152dbc0c95060a5e 909 Gene3D G3DSA:3.40.50.2000 726 892 1.0E-21 T 28-03-2018 CO689_RS06895 ee7afb2c6109db3a152dbc0c95060a5e 909 SUPERFAMILY SSF53756 111 374 2.93E-14 T 28-03-2018 CO689_RS06895 ee7afb2c6109db3a152dbc0c95060a5e 909 Gene3D G3DSA:3.40.50.2000 194 352 2.2E-4 T 28-03-2018 CO689_RS06895 ee7afb2c6109db3a152dbc0c95060a5e 909 SUPERFAMILY SSF53756 738 891 8.9E-27 T 28-03-2018 CO689_RS13675 a33bc59af6342779cd404ebcfa4c326f 232 Pfam PF06149 Protein of unknown function (DUF969) 3 221 1.4E-86 T 28-03-2018 IPR010374 Protein of unknown function DUF969 CO689_RS04095 28fdfd6bc6fd15f980f4532b62a14384 464 Pfam PF07690 Major Facilitator Superfamily 18 413 8.0E-49 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CO689_RS04095 28fdfd6bc6fd15f980f4532b62a14384 464 Gene3D G3DSA:1.20.1250.20 261 464 8.2E-25 T 28-03-2018 CO689_RS04095 28fdfd6bc6fd15f980f4532b62a14384 464 SUPERFAMILY SSF103473 4 195 6.28E-59 T 28-03-2018 IPR020846 Major facilitator superfamily domain CO689_RS04095 28fdfd6bc6fd15f980f4532b62a14384 464 SUPERFAMILY SSF103473 251 461 6.28E-59 T 28-03-2018 IPR020846 Major facilitator superfamily domain CO689_RS04095 28fdfd6bc6fd15f980f4532b62a14384 464 Gene3D G3DSA:1.20.1250.20 2 200 2.2E-31 T 28-03-2018 CO689_RS08780 17312904b87cd4081bf0630400b31ff4 511 Pfam PF00939 Sodium:sulfate symporter transmembrane region 23 510 3.1E-104 T 28-03-2018 IPR001898 Solute carrier family 13 GO:0005215|GO:0006814|GO:0016020|GO:0055085 Reactome: R-HSA-433137 CO689_RS08780 17312904b87cd4081bf0630400b31ff4 511 TIGRFAM TIGR00785 dass: transporter, divalent anion:Na+ symporter (DASS) family 40 505 2.3E-76 T 28-03-2018 IPR001898 Solute carrier family 13 GO:0005215|GO:0006814|GO:0016020|GO:0055085 Reactome: R-HSA-433137 CO689_RS08780 17312904b87cd4081bf0630400b31ff4 511 PIRSF PIRSF002457 3 511 1.5E-129 T 28-03-2018 IPR030676 Citrate carrier CitT-related CO689_RS08360 62ad7995b13baac55cff209d80297cab 247 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 128 195 4.0E-8 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CO689_RS08360 62ad7995b13baac55cff209d80297cab 247 Pfam PF13419 Haloacid dehalogenase-like hydrolase 9 195 8.6E-31 T 28-03-2018 IPR023214 HAD-like domain CO689_RS08360 62ad7995b13baac55cff209d80297cab 247 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 139 155 4.8E-13 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CO689_RS08360 62ad7995b13baac55cff209d80297cab 247 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 157 177 4.8E-13 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CO689_RS08360 62ad7995b13baac55cff209d80297cab 247 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 6 17 4.8E-13 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CO689_RS08360 62ad7995b13baac55cff209d80297cab 247 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 108 121 4.8E-13 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CO689_RS08360 62ad7995b13baac55cff209d80297cab 247 SUPERFAMILY SSF56784 6 228 8.93E-41 T 28-03-2018 IPR023214 HAD-like domain CO689_RS08360 62ad7995b13baac55cff209d80297cab 247 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 99 190 1.0E-10 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CO689_RS08360 62ad7995b13baac55cff209d80297cab 247 Gene3D G3DSA:3.40.50.1000 1 42 0.057 T 28-03-2018 IPR023214 HAD-like domain CO689_RS08360 62ad7995b13baac55cff209d80297cab 247 Gene3D G3DSA:3.40.50.1000 76 235 1.5E-29 T 28-03-2018 IPR023214 HAD-like domain CO689_RS06990 fb2d9c5a0517953459365175e05a4f5c 504 Gene3D G3DSA:1.20.200.10 198 503 9.3E-117 T 28-03-2018 CO689_RS06990 fb2d9c5a0517953459365175e05a4f5c 504 SUPERFAMILY SSF48557 3 498 5.42E-185 T 28-03-2018 IPR008948 L-Aspartase-like GO:0003824 CO689_RS06990 fb2d9c5a0517953459365175e05a4f5c 504 ProSitePatterns PS00488 Phenylalanine and histidine ammonia-lyases signature. 138 154 - T 28-03-2018 IPR022313 Phenylalanine/histidine ammonia-lyases, active site GO:0016841 Reactome: R-HSA-70921 CO689_RS06990 fb2d9c5a0517953459365175e05a4f5c 504 TIGRFAM TIGR01225 hutH: histidine ammonia-lyase 4 501 1.7E-200 T 28-03-2018 IPR005921 Histidine ammonia-lyase GO:0004397|GO:0005737|GO:0006548 KEGG: 00340+4.3.1.3|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 CO689_RS06990 fb2d9c5a0517953459365175e05a4f5c 504 Hamap MF_00229 Histidine ammonia-lyase [hutH]. 2 504 43.921 T 28-03-2018 IPR005921 Histidine ammonia-lyase GO:0004397|GO:0005737|GO:0006548 KEGG: 00340+4.3.1.3|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 CO689_RS06990 fb2d9c5a0517953459365175e05a4f5c 504 Pfam PF00221 Aromatic amino acid lyase 10 470 7.4E-186 T 28-03-2018 IPR001106 Aromatic amino acid lyase Reactome: R-HSA-70921 CO689_RS06990 fb2d9c5a0517953459365175e05a4f5c 504 Gene3D G3DSA:1.10.275.10 1 196 1.6E-70 T 28-03-2018 IPR024083 Fumarase/histidase, N-terminal CO689_RS08170 4fe42ef5072f336aeeb62d8de402e150 188 Pfam PF03358 NADPH-dependent FMN reductase 1 141 1.2E-29 T 28-03-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 CO689_RS08170 4fe42ef5072f336aeeb62d8de402e150 188 Gene3D G3DSA:3.40.50.360 1 185 1.0E-30 T 28-03-2018 IPR029039 Flavoprotein-like domain CO689_RS08170 4fe42ef5072f336aeeb62d8de402e150 188 SUPERFAMILY SSF52218 1 166 1.49E-33 T 28-03-2018 IPR029039 Flavoprotein-like domain CO689_RS05355 0a0c48d85b5129b9266390e538ebb77d 562 SUPERFAMILY SSF54373 296 478 1.37E-56 T 28-03-2018 CO689_RS05355 0a0c48d85b5129b9266390e538ebb77d 562 ProSitePatterns PS00623 GMC oxidoreductases signature 1. 86 109 - T 28-03-2018 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 CO689_RS05355 0a0c48d85b5129b9266390e538ebb77d 562 PIRSF PIRSF000137 1 540 4.5E-143 T 28-03-2018 IPR012132 Glucose-methanol-choline oxidoreductase GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 CO689_RS05355 0a0c48d85b5129b9266390e538ebb77d 562 ProSitePatterns PS00624 GMC oxidoreductases signature 2. 260 274 - T 28-03-2018 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 CO689_RS05355 0a0c48d85b5129b9266390e538ebb77d 562 Gene3D G3DSA:3.30.560.10 107 493 8.1E-104 T 28-03-2018 CO689_RS05355 0a0c48d85b5129b9266390e538ebb77d 562 SUPERFAMILY SSF51905 4 294 1.13E-85 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CO689_RS05355 0a0c48d85b5129b9266390e538ebb77d 562 SUPERFAMILY SSF51905 477 538 1.13E-85 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CO689_RS05355 0a0c48d85b5129b9266390e538ebb77d 562 Hamap MF_00750 Oxygen-dependent choline dehydrogenase [betA]. 5 558 59.201 T 28-03-2018 IPR011533 Oxygen-dependent choline dehydrogenase GO:0008812|GO:0019285 KEGG: 00260+1.2.1.8+1.1.99.1|MetaCyc: PWY-3722|MetaCyc: PWY-7494 CO689_RS05355 0a0c48d85b5129b9266390e538ebb77d 562 Pfam PF05199 GMC oxidoreductase 393 531 1.2E-36 T 28-03-2018 IPR007867 Glucose-methanol-choline oxidoreductase, C-terminal GO:0016614|GO:0055114 Reactome: R-HSA-6798163 CO689_RS05355 0a0c48d85b5129b9266390e538ebb77d 562 Gene3D G3DSA:4.10.450.10 42 106 2.0E-22 T 28-03-2018 CO689_RS05355 0a0c48d85b5129b9266390e538ebb77d 562 TIGRFAM TIGR01810 betA: choline dehydrogenase 8 540 4.8E-282 T 28-03-2018 IPR011533 Oxygen-dependent choline dehydrogenase GO:0008812|GO:0019285 KEGG: 00260+1.2.1.8+1.1.99.1|MetaCyc: PWY-3722|MetaCyc: PWY-7494 CO689_RS05355 0a0c48d85b5129b9266390e538ebb77d 562 Pfam PF00732 GMC oxidoreductase 7 301 5.8E-81 T 28-03-2018 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 CO689_RS04950 57d002c2f9c0c106bb1309adc59bb708 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 184 201 2.1E-47 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CO689_RS04950 57d002c2f9c0c106bb1309adc59bb708 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 13 30 2.1E-47 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CO689_RS04950 57d002c2f9c0c106bb1309adc59bb708 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 220 240 2.1E-47 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CO689_RS04950 57d002c2f9c0c106bb1309adc59bb708 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 88 99 2.1E-47 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CO689_RS04950 57d002c2f9c0c106bb1309adc59bb708 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 163 182 2.1E-47 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CO689_RS04950 57d002c2f9c0c106bb1309adc59bb708 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 135 151 2.1E-47 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CO689_RS04950 57d002c2f9c0c106bb1309adc59bb708 259 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 141 149 1.0E-13 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CO689_RS04950 57d002c2f9c0c106bb1309adc59bb708 259 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 163 182 1.0E-13 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CO689_RS04950 57d002c2f9c0c106bb1309adc59bb708 259 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 88 99 1.0E-13 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CO689_RS04950 57d002c2f9c0c106bb1309adc59bb708 259 SUPERFAMILY SSF51735 10 258 2.43E-84 T 28-03-2018 IPR016040 NAD(P)-binding domain CO689_RS04950 57d002c2f9c0c106bb1309adc59bb708 259 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 150 178 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CO689_RS04950 57d002c2f9c0c106bb1309adc59bb708 259 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 19 257 8.4E-68 T 28-03-2018 CO689_RS04950 57d002c2f9c0c106bb1309adc59bb708 259 Gene3D G3DSA:3.40.50.720 4 56 1.4E-11 T 28-03-2018 CO689_RS04950 57d002c2f9c0c106bb1309adc59bb708 259 Gene3D G3DSA:3.40.50.720 57 259 6.6E-63 T 28-03-2018 CO689_RS11475 7be9b0644c68a930dfef161c3ebd8224 220 SUPERFAMILY SSF51366 1 214 3.36E-67 T 28-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 CO689_RS11475 7be9b0644c68a930dfef161c3ebd8224 220 TIGRFAM TIGR01163 rpe: ribulose-phosphate 3-epimerase 4 213 9.3E-83 T 28-03-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 CO689_RS11475 7be9b0644c68a930dfef161c3ebd8224 220 ProSitePatterns PS01085 Ribulose-phosphate 3-epimerase family signature 1. 31 45 - T 28-03-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 CO689_RS11475 7be9b0644c68a930dfef161c3ebd8224 220 ProSitePatterns PS01086 Ribulose-phosphate 3-epimerase family signature 2. 133 155 - T 28-03-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 CO689_RS11475 7be9b0644c68a930dfef161c3ebd8224 220 Pfam PF00834 Ribulose-phosphate 3 epimerase family 3 200 1.5E-74 T 28-03-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 CO689_RS11475 7be9b0644c68a930dfef161c3ebd8224 220 PIRSF PIRSF001461 1 220 5.7E-84 T 28-03-2018 IPR026019 Ribulose-phosphate 3-epimerase GO:0004750|GO:0006098 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 CO689_RS11475 7be9b0644c68a930dfef161c3ebd8224 220 Gene3D G3DSA:3.20.20.70 1 217 1.7E-77 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CO689_RS13840 555b8dd7f681ed3886b53f1add15c3b1 322 Gene3D G3DSA:3.40.50.450 182 302 8.2E-17 T 28-03-2018 CO689_RS13840 555b8dd7f681ed3886b53f1add15c3b1 322 SUPERFAMILY SSF53784 1 312 8.11E-115 T 28-03-2018 IPR000023 Phosphofructokinase domain GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CO689_RS13840 555b8dd7f681ed3886b53f1add15c3b1 322 TIGRFAM TIGR02482 PFKA_ATP: 6-phosphofructokinase 3 301 8.0E-132 T 28-03-2018 IPR012828 ATP-dependent 6-phosphofructokinase, prokaryotic GO:0003872|GO:0005524|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 CO689_RS13840 555b8dd7f681ed3886b53f1add15c3b1 322 Pfam PF00365 Phosphofructokinase 3 277 9.1E-114 T 28-03-2018 IPR000023 Phosphofructokinase domain GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CO689_RS13840 555b8dd7f681ed3886b53f1add15c3b1 322 Hamap MF_00339 ATP-dependent 6-phosphofructokinase [pfkA]. 1 321 47.346 T 28-03-2018 IPR012828 ATP-dependent 6-phosphofructokinase, prokaryotic GO:0003872|GO:0005524|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 CO689_RS13840 555b8dd7f681ed3886b53f1add15c3b1 322 ProSitePatterns PS00433 Phosphofructokinase signature. 245 263 - T 28-03-2018 IPR015912 Phosphofructokinase, conserved site GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CO689_RS13840 555b8dd7f681ed3886b53f1add15c3b1 322 Gene3D G3DSA:3.40.50.450 1 181 5.5E-77 T 28-03-2018 CO689_RS13840 555b8dd7f681ed3886b53f1add15c3b1 322 PIRSF PIRSF000532 1 322 3.7E-120 T 28-03-2018 IPR012003 ATP-dependent 6-phosphofructokinase, prokaryotic-type GO:0005524|GO:0006002|GO:0006096|GO:0008443 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 CO689_RS13840 555b8dd7f681ed3886b53f1add15c3b1 322 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 241 263 1.4E-87 T 28-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CO689_RS13840 555b8dd7f681ed3886b53f1add15c3b1 322 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 140 158 1.4E-87 T 28-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CO689_RS13840 555b8dd7f681ed3886b53f1add15c3b1 322 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 160 176 1.4E-87 T 28-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CO689_RS13840 555b8dd7f681ed3886b53f1add15c3b1 322 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 122 139 1.4E-87 T 28-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CO689_RS13840 555b8dd7f681ed3886b53f1add15c3b1 322 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 178 195 1.4E-87 T 28-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CO689_RS13840 555b8dd7f681ed3886b53f1add15c3b1 322 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 31 44 1.4E-87 T 28-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CO689_RS13840 555b8dd7f681ed3886b53f1add15c3b1 322 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 6 25 1.4E-87 T 28-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CO689_RS13840 555b8dd7f681ed3886b53f1add15c3b1 322 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 93 109 1.4E-87 T 28-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CO689_RS13840 555b8dd7f681ed3886b53f1add15c3b1 322 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 214 226 1.4E-87 T 28-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CO689_RS01940 9e96634bd30067a84f5bf56a371e87de 187 Gene3D G3DSA:3.40.30.10 1 167 8.2E-10 T 28-03-2018 CO689_RS01940 9e96634bd30067a84f5bf56a371e87de 187 Pfam PF14595 Thioredoxin 13 138 4.5E-38 T 28-03-2018 CO689_RS01940 9e96634bd30067a84f5bf56a371e87de 187 SUPERFAMILY SSF52833 61 129 6.9E-6 T 28-03-2018 IPR012336 Thioredoxin-like fold CO689_RS13185 e231ea389424fcbabcceac2f794736aa 296 Gene3D G3DSA:3.20.20.150 1 296 4.5E-60 T 28-03-2018 CO689_RS13185 e231ea389424fcbabcceac2f794736aa 296 SUPERFAMILY SSF51658 1 293 1.7E-101 T 28-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain CO689_RS13185 e231ea389424fcbabcceac2f794736aa 296 Pfam PF01261 Xylose isomerase-like TIM barrel 20 236 1.9E-39 T 28-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain CO689_RS13185 e231ea389424fcbabcceac2f794736aa 296 TIGRFAM TIGR00587 nfo: apurinic endonuclease (APN1) 2 281 1.1E-98 T 28-03-2018 IPR001719 AP endonuclease 2 GO:0003677|GO:0006281|GO:0008270 CO689_RS13185 e231ea389424fcbabcceac2f794736aa 296 Hamap MF_00152 Probable endonuclease 4 [nfo]. 1 284 43.122 T 28-03-2018 IPR001719 AP endonuclease 2 GO:0003677|GO:0006281|GO:0008270 CO689_RS13185 e231ea389424fcbabcceac2f794736aa 296 ProSitePatterns PS00729 AP endonucleases family 2 signature 1. 68 76 - T 28-03-2018 IPR018246 AP endonuclease 2, zinc binding site GO:0008270 CO689_RS13185 e231ea389424fcbabcceac2f794736aa 296 SMART SM00518 2 284 1.3E-122 T 28-03-2018 IPR001719 AP endonuclease 2 GO:0003677|GO:0006281|GO:0008270 CO689_RS13185 e231ea389424fcbabcceac2f794736aa 296 ProSitePatterns PS00730 AP endonucleases family 2 signature 2. 174 181 - T 28-03-2018 IPR018246 AP endonuclease 2, zinc binding site GO:0008270 CO689_RS13185 e231ea389424fcbabcceac2f794736aa 296 ProSitePatterns PS00731 AP endonucleases family 2 signature 3. 212 228 - T 28-03-2018 IPR018246 AP endonuclease 2, zinc binding site GO:0008270 CO689_RS05765 f8097ce71935734fc2ac82c3a20e9e75 498 TIGRFAM TIGR00931 antiport_nhaC: Na+/H+ antiporter NhaC 29 473 4.4E-141 T 28-03-2018 IPR004770 Na+/H+ antiporter NhaC GO:0015297|GO:0016021 CO689_RS05765 f8097ce71935734fc2ac82c3a20e9e75 498 Pfam PF03553 Na+/H+ antiporter family 177 468 1.0E-66 T 28-03-2018 IPR018461 Na+/H+ antiporter, NhaC-like, C-terminal GO:0016021 CO689_RS08565 c75809bb1607d93626d19c4a7ddab607 347 Gene3D G3DSA:3.30.565.10 137 331 2.9E-32 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CO689_RS08565 c75809bb1607d93626d19c4a7ddab607 347 SUPERFAMILY SSF47384 108 176 4.32E-6 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CO689_RS08565 c75809bb1607d93626d19c4a7ddab607 347 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 226 332 6.4E-19 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CO689_RS08565 c75809bb1607d93626d19c4a7ddab607 347 PRINTS PR00344 Bacterial sensor protein C-terminal signature 277 287 2.2E-5 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CO689_RS08565 c75809bb1607d93626d19c4a7ddab607 347 PRINTS PR00344 Bacterial sensor protein C-terminal signature 317 330 2.2E-5 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CO689_RS08565 c75809bb1607d93626d19c4a7ddab607 347 PRINTS PR00344 Bacterial sensor protein C-terminal signature 259 273 2.2E-5 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CO689_RS08565 c75809bb1607d93626d19c4a7ddab607 347 PRINTS PR00344 Bacterial sensor protein C-terminal signature 293 311 2.2E-5 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CO689_RS08565 c75809bb1607d93626d19c4a7ddab607 347 SMART SM00387 222 333 1.3E-21 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CO689_RS08565 c75809bb1607d93626d19c4a7ddab607 347 SUPERFAMILY SSF55874 167 331 2.49E-31 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CO689_RS00925 2ae2837060ec8a2932fc1d307156d761 488 Gene3D G3DSA:3.30.1360.60 410 485 8.6E-26 T 28-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 CO689_RS00925 2ae2837060ec8a2932fc1d307156d761 488 Pfam PF02378 Phosphotransferase system, EIIC 10 316 9.1E-72 T 28-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 CO689_RS00925 2ae2837060ec8a2932fc1d307156d761 488 Pfam PF00367 phosphotransferase system, EIIB 414 446 2.0E-14 T 28-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 CO689_RS00925 2ae2837060ec8a2932fc1d307156d761 488 SUPERFAMILY SSF55604 413 485 1.11E-19 T 28-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 CO689_RS00925 2ae2837060ec8a2932fc1d307156d761 488 ProSitePatterns PS01035 PTS EIIB domains cysteine phosphorylation site signature. 424 441 - T 28-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 CO689_RS00925 2ae2837060ec8a2932fc1d307156d761 488 TIGRFAM TIGR00826 EIIB_glc: PTS system, glucose-like IIB component 377 471 6.1E-17 T 28-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 CO689_RS00925 2ae2837060ec8a2932fc1d307156d761 488 TIGRFAM TIGR01998 PTS-II-BC-nag: PTS system, N-acetylglucosamine-specific IIBC component 1 481 1.1E-196 T 28-03-2018 IPR010974 Phosphotransferase system, N-acetylglucosamine-specific IIBC component GO:0008982|GO:0009401|GO:0015572|GO:0016021|GO:0019866 CO689_RS04945 fcdaa3d57c423d8a705e3ca9a340cd54 719 TIGRFAM TIGR01168 YSIRK_signal: gram-positive signal peptide, YSIRK family 2 35 2.4E-11 T 28-03-2018 IPR005877 YSIRK Gram-positive signal peptide GO:0016020 CO689_RS04945 fcdaa3d57c423d8a705e3ca9a340cd54 719 Pfam PF04650 YSIRK type signal peptide 2 27 6.4E-9 T 28-03-2018 IPR005877 YSIRK Gram-positive signal peptide GO:0016020 CO689_RS04945 fcdaa3d57c423d8a705e3ca9a340cd54 719 Gene3D G3DSA:1.20.5.420 430 490 7.7E-7 T 28-03-2018 CO689_RS04945 fcdaa3d57c423d8a705e3ca9a340cd54 719 Gene3D G3DSA:1.20.5.420 45 102 1.5E-5 T 28-03-2018 CO689_RS04945 fcdaa3d57c423d8a705e3ca9a340cd54 719 Gene3D G3DSA:1.20.5.420 131 187 5.9E-5 T 28-03-2018 CO689_RS04945 fcdaa3d57c423d8a705e3ca9a340cd54 719 Gene3D G3DSA:1.20.5.420 270 339 3.9E-8 T 28-03-2018 CO689_RS04945 fcdaa3d57c423d8a705e3ca9a340cd54 719 Gene3D G3DSA:1.20.5.420 566 628 6.1E-5 T 28-03-2018 CO689_RS04945 fcdaa3d57c423d8a705e3ca9a340cd54 719 Gene3D G3DSA:1.20.5.420 359 418 3.5E-7 T 28-03-2018 CO689_RS04945 fcdaa3d57c423d8a705e3ca9a340cd54 719 Gene3D G3DSA:1.20.5.420 506 564 0.0076 T 28-03-2018 CO689_RS04945 fcdaa3d57c423d8a705e3ca9a340cd54 719 Gene3D G3DSA:1.20.5.420 204 260 3.5E-5 T 28-03-2018 CO689_RS04945 fcdaa3d57c423d8a705e3ca9a340cd54 719 Pfam PF00746 LPXTG cell wall anchor motif 676 718 1.3E-7 T 28-03-2018 IPR019948 Gram-positive LPXTG cell wall anchor CO689_RS04945 fcdaa3d57c423d8a705e3ca9a340cd54 719 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 681 716 3.9E-4 T 28-03-2018 CO689_RS10625 24797212603e11972ce595068f41e69f 429 Pfam PF02040 Arsenical pump membrane protein 4 425 1.5E-186 T 28-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 CO689_RS10625 24797212603e11972ce595068f41e69f 429 PRINTS PR00758 Arsenical pump membrane protein signature 365 390 2.5E-110 T 28-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 CO689_RS10625 24797212603e11972ce595068f41e69f 429 PRINTS PR00758 Arsenical pump membrane protein signature 218 243 2.5E-110 T 28-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 CO689_RS10625 24797212603e11972ce595068f41e69f 429 PRINTS PR00758 Arsenical pump membrane protein signature 102 126 2.5E-110 T 28-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 CO689_RS10625 24797212603e11972ce595068f41e69f 429 PRINTS PR00758 Arsenical pump membrane protein signature 398 422 2.5E-110 T 28-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 CO689_RS10625 24797212603e11972ce595068f41e69f 429 PRINTS PR00758 Arsenical pump membrane protein signature 279 303 2.5E-110 T 28-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 CO689_RS10625 24797212603e11972ce595068f41e69f 429 PRINTS PR00758 Arsenical pump membrane protein signature 178 201 2.5E-110 T 28-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 CO689_RS10625 24797212603e11972ce595068f41e69f 429 PRINTS PR00758 Arsenical pump membrane protein signature 145 169 2.5E-110 T 28-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 CO689_RS10625 24797212603e11972ce595068f41e69f 429 PRINTS PR00758 Arsenical pump membrane protein signature 324 346 2.5E-110 T 28-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 CO689_RS10625 24797212603e11972ce595068f41e69f 429 TIGRFAM TIGR00935 2a45: arsenite/antimonite efflux pump membrane protein 3 427 4.5E-217 T 28-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 CO689_RS04900 dbd4cdcab534f8a7f924a36636808bde 150 Gene3D G3DSA:1.10.10.10 3 67 7.6E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS04900 dbd4cdcab534f8a7f924a36636808bde 150 Gene3D G3DSA:3.30.1360.40 76 148 1.9E-16 T 28-03-2018 IPR024946 Arginine repressor C-terminal-like domain Reactome: R-HSA-4615885 CO689_RS04900 dbd4cdcab534f8a7f924a36636808bde 150 SUPERFAMILY SSF46785 3 75 3.46E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS04900 dbd4cdcab534f8a7f924a36636808bde 150 PRINTS PR01467 Bacterial arginine repressor signature 120 135 4.0E-7 T 28-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 CO689_RS04900 dbd4cdcab534f8a7f924a36636808bde 150 PRINTS PR01467 Bacterial arginine repressor signature 38 53 4.0E-7 T 28-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 CO689_RS04900 dbd4cdcab534f8a7f924a36636808bde 150 PRINTS PR01467 Bacterial arginine repressor signature 90 103 4.0E-7 T 28-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 CO689_RS04900 dbd4cdcab534f8a7f924a36636808bde 150 Pfam PF01316 Arginine repressor, DNA binding domain 1 69 3.6E-10 T 28-03-2018 IPR020900 Arginine repressor, DNA-binding domain GO:0003700|GO:0006355|GO:0006525 CO689_RS04900 dbd4cdcab534f8a7f924a36636808bde 150 Hamap MF_00173 Arginine repressor [argR]. 1 150 30.963 T 28-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 CO689_RS04900 dbd4cdcab534f8a7f924a36636808bde 150 Pfam PF02863 Arginine repressor, C-terminal domain 84 144 2.6E-15 T 28-03-2018 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 CO689_RS04900 dbd4cdcab534f8a7f924a36636808bde 150 SUPERFAMILY SSF55252 84 148 2.09E-15 T 28-03-2018 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 CO689_RS04900 dbd4cdcab534f8a7f924a36636808bde 150 ProDom PD007402 ARGININE REPRESSOR TRANSCRIPTION BIOSYNTHESIS DNA-BINDING REGULATION AMINO-ACID ARGR TRANSCRIPTIONAL FAMILY 93 128 1.0E-7 T 28-03-2018 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 CO689_RS12920 8bcb0d95b9761ca6d2ac66ff4d946702 306 SUPERFAMILY SSF56281 1 305 1.14E-71 T 28-03-2018 IPR001279 Metallo-beta-lactamase CO689_RS12920 8bcb0d95b9761ca6d2ac66ff4d946702 306 Gene3D G3DSA:3.60.15.10 1 306 1.3E-55 T 28-03-2018 IPR001279 Metallo-beta-lactamase CO689_RS12920 8bcb0d95b9761ca6d2ac66ff4d946702 306 Hamap MF_01818 Ribonuclease BN [rbn]. 1 306 35.165 T 28-03-2018 IPR013471 Ribonuclease Z/BN GO:0016891|GO:0042779 CO689_RS12920 8bcb0d95b9761ca6d2ac66ff4d946702 306 Pfam PF12706 Beta-lactamase superfamily domain 50 153 3.2E-11 T 28-03-2018 IPR001279 Metallo-beta-lactamase CO689_RS12920 8bcb0d95b9761ca6d2ac66ff4d946702 306 TIGRFAM TIGR02651 RNase_Z: ribonuclease Z 2 304 8.5E-100 T 28-03-2018 IPR013471 Ribonuclease Z/BN GO:0016891|GO:0042779 CO689_RS00365 acc35563653d2ab08beff751640c50b2 182 Pfam PF07883 Cupin domain 123 177 2.5E-7 T 28-03-2018 IPR013096 Cupin 2, conserved barrel CO689_RS00365 acc35563653d2ab08beff751640c50b2 182 Gene3D G3DSA:2.60.120.10 74 182 1.9E-9 T 28-03-2018 IPR014710 RmlC-like jelly roll fold CO689_RS00365 acc35563653d2ab08beff751640c50b2 182 SUPERFAMILY SSF51182 90 180 3.69E-13 T 28-03-2018 IPR011051 RmlC-like cupin domain CO689_RS00365 acc35563653d2ab08beff751640c50b2 182 SUPERFAMILY SSF47413 5 69 2.14E-13 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CO689_RS00365 acc35563653d2ab08beff751640c50b2 182 Pfam PF01381 Helix-turn-helix 12 64 1.0E-10 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CO689_RS00365 acc35563653d2ab08beff751640c50b2 182 SMART SM00530 11 66 1.9E-10 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CO689_RS00365 acc35563653d2ab08beff751640c50b2 182 Gene3D G3DSA:1.10.260.40 4 73 6.0E-12 T 28-03-2018 CO689_RS05300 039fd0be2a7a45913d607ef1ace3386a 190 SUPERFAMILY SSF46689 6 71 1.33E-12 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CO689_RS05300 039fd0be2a7a45913d607ef1ace3386a 190 Pfam PF00440 Bacterial regulatory proteins, tetR family 21 59 3.8E-5 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CO689_RS05300 039fd0be2a7a45913d607ef1ace3386a 190 Gene3D G3DSA:1.10.10.60 50 153 5.5E-5 T 28-03-2018 CO689_RS05300 039fd0be2a7a45913d607ef1ace3386a 190 Gene3D G3DSA:1.10.10.60 9 49 3.2E-9 T 28-03-2018 CO689_RS06350 176a15b528fc0c6432adcadf5dfeda84 373 SUPERFAMILY SSF51261 171 369 4.66E-40 T 28-03-2018 IPR011055 Duplicated hybrid motif CO689_RS06350 176a15b528fc0c6432adcadf5dfeda84 373 Pfam PF01551 Peptidase family M23 265 359 1.1E-27 T 28-03-2018 IPR016047 Peptidase M23 CO689_RS06350 176a15b528fc0c6432adcadf5dfeda84 373 Gene3D G3DSA:2.70.70.10 231 373 3.2E-35 T 28-03-2018 CO689_RS04470 40bfcabcd168adf0b6e7c30ec7a0ddbb 2059 Pfam PF00746 LPXTG cell wall anchor motif 2013 2056 1.7E-9 T 28-03-2018 IPR019948 Gram-positive LPXTG cell wall anchor CO689_RS04470 40bfcabcd168adf0b6e7c30ec7a0ddbb 2059 TIGRFAM TIGR01168 YSIRK_signal: gram-positive signal peptide, YSIRK family 13 48 8.0E-12 T 28-03-2018 IPR005877 YSIRK Gram-positive signal peptide GO:0016020 CO689_RS04470 40bfcabcd168adf0b6e7c30ec7a0ddbb 2059 Gene3D G3DSA:2.60.40.1290 506 669 7.1E-31 T 28-03-2018 CO689_RS04470 40bfcabcd168adf0b6e7c30ec7a0ddbb 2059 Pfam PF17210 SdrD B-like domain 1030 1132 1.2E-28 T 28-03-2018 IPR033764 SD-repeat containing protein, B domain CO689_RS04470 40bfcabcd168adf0b6e7c30ec7a0ddbb 2059 Pfam PF17210 SdrD B-like domain 1147 1249 5.3E-29 T 28-03-2018 IPR033764 SD-repeat containing protein, B domain CO689_RS04470 40bfcabcd168adf0b6e7c30ec7a0ddbb 2059 Pfam PF17210 SdrD B-like domain 1614 1716 2.1E-29 T 28-03-2018 IPR033764 SD-repeat containing protein, B domain CO689_RS04470 40bfcabcd168adf0b6e7c30ec7a0ddbb 2059 Pfam PF17210 SdrD B-like domain 794 897 8.8E-29 T 28-03-2018 IPR033764 SD-repeat containing protein, B domain CO689_RS04470 40bfcabcd168adf0b6e7c30ec7a0ddbb 2059 Pfam PF17210 SdrD B-like domain 1497 1599 1.0E-28 T 28-03-2018 IPR033764 SD-repeat containing protein, B domain CO689_RS04470 40bfcabcd168adf0b6e7c30ec7a0ddbb 2059 Pfam PF17210 SdrD B-like domain 1731 1833 1.1E-28 T 28-03-2018 IPR033764 SD-repeat containing protein, B domain CO689_RS04470 40bfcabcd168adf0b6e7c30ec7a0ddbb 2059 Pfam PF17210 SdrD B-like domain 1264 1365 8.7E-28 T 28-03-2018 IPR033764 SD-repeat containing protein, B domain CO689_RS04470 40bfcabcd168adf0b6e7c30ec7a0ddbb 2059 Pfam PF17210 SdrD B-like domain 681 785 2.5E-31 T 28-03-2018 IPR033764 SD-repeat containing protein, B domain CO689_RS04470 40bfcabcd168adf0b6e7c30ec7a0ddbb 2059 Pfam PF17210 SdrD B-like domain 1380 1482 1.8E-28 T 28-03-2018 IPR033764 SD-repeat containing protein, B domain CO689_RS04470 40bfcabcd168adf0b6e7c30ec7a0ddbb 2059 Pfam PF17210 SdrD B-like domain 912 1014 4.1E-29 T 28-03-2018 IPR033764 SD-repeat containing protein, B domain CO689_RS04470 40bfcabcd168adf0b6e7c30ec7a0ddbb 2059 SUPERFAMILY SSF117074 774 879 1.83E-19 T 28-03-2018 CO689_RS04470 40bfcabcd168adf0b6e7c30ec7a0ddbb 2059 Pfam PF10425 C-terminus of bacterial fibrinogen-binding adhesin 516 662 2.5E-23 T 28-03-2018 IPR011266 Fibrinogen-binding domain 2 GO:0005618|GO:0007155 CO689_RS04470 40bfcabcd168adf0b6e7c30ec7a0ddbb 2059 SUPERFAMILY SSF117074 1489 1596 5.62E-24 T 28-03-2018 CO689_RS04470 40bfcabcd168adf0b6e7c30ec7a0ddbb 2059 SUPERFAMILY SSF117074 1703 1802 1.83E-21 T 28-03-2018 CO689_RS04470 40bfcabcd168adf0b6e7c30ec7a0ddbb 2059 SUPERFAMILY SSF117074 1358 1479 2.35E-23 T 28-03-2018 CO689_RS04470 40bfcabcd168adf0b6e7c30ec7a0ddbb 2059 SUPERFAMILY SSF117074 1121 1246 4.45E-24 T 28-03-2018 CO689_RS04470 40bfcabcd168adf0b6e7c30ec7a0ddbb 2059 Gene3D G3DSA:2.60.40.1280 358 504 1.7E-32 T 28-03-2018 IPR011252 Fibrogen-binding domain 1 GO:0005618|GO:0007155 CO689_RS04470 40bfcabcd168adf0b6e7c30ec7a0ddbb 2059 SUPERFAMILY SSF117074 1256 1361 1.83E-23 T 28-03-2018 CO689_RS04470 40bfcabcd168adf0b6e7c30ec7a0ddbb 2059 SUPERFAMILY SSF49401 512 700 8.2E-32 T 28-03-2018 IPR008966 Adhesion domain CO689_RS04470 40bfcabcd168adf0b6e7c30ec7a0ddbb 2059 SUPERFAMILY SSF117074 880 992 2.22E-19 T 28-03-2018 CO689_RS04470 40bfcabcd168adf0b6e7c30ec7a0ddbb 2059 Pfam PF04650 YSIRK type signal peptide 14 38 2.7E-10 T 28-03-2018 IPR005877 YSIRK Gram-positive signal peptide GO:0016020 CO689_RS04470 40bfcabcd168adf0b6e7c30ec7a0ddbb 2059 SUPERFAMILY SSF49401 358 502 6.59E-26 T 28-03-2018 IPR008966 Adhesion domain CO689_RS04470 40bfcabcd168adf0b6e7c30ec7a0ddbb 2059 SUPERFAMILY SSF117074 1588 1705 4.18E-21 T 28-03-2018 CO689_RS04470 40bfcabcd168adf0b6e7c30ec7a0ddbb 2059 SUPERFAMILY SSF117074 677 765 1.44E-22 T 28-03-2018 CO689_RS04470 40bfcabcd168adf0b6e7c30ec7a0ddbb 2059 Gene3D G3DSA:2.60.40.10 1726 1844 1.3E-25 T 28-03-2018 IPR013783 Immunoglobulin-like fold CO689_RS04470 40bfcabcd168adf0b6e7c30ec7a0ddbb 2059 Gene3D G3DSA:2.60.40.10 1377 1492 4.3E-27 T 28-03-2018 IPR013783 Immunoglobulin-like fold CO689_RS04470 40bfcabcd168adf0b6e7c30ec7a0ddbb 2059 Gene3D G3DSA:2.60.40.10 907 1023 7.3E-26 T 28-03-2018 IPR013783 Immunoglobulin-like fold CO689_RS04470 40bfcabcd168adf0b6e7c30ec7a0ddbb 2059 Gene3D G3DSA:2.60.40.10 793 905 4.7E-22 T 28-03-2018 IPR013783 Immunoglobulin-like fold CO689_RS04470 40bfcabcd168adf0b6e7c30ec7a0ddbb 2059 Gene3D G3DSA:2.60.40.10 1025 1141 1.1E-25 T 28-03-2018 IPR013783 Immunoglobulin-like fold CO689_RS04470 40bfcabcd168adf0b6e7c30ec7a0ddbb 2059 Gene3D G3DSA:2.60.40.10 1609 1724 5.9E-28 T 28-03-2018 IPR013783 Immunoglobulin-like fold CO689_RS04470 40bfcabcd168adf0b6e7c30ec7a0ddbb 2059 Gene3D G3DSA:2.60.40.10 676 792 3.2E-26 T 28-03-2018 IPR013783 Immunoglobulin-like fold CO689_RS04470 40bfcabcd168adf0b6e7c30ec7a0ddbb 2059 Gene3D G3DSA:2.60.40.10 1493 1607 1.1E-26 T 28-03-2018 IPR013783 Immunoglobulin-like fold CO689_RS04470 40bfcabcd168adf0b6e7c30ec7a0ddbb 2059 Gene3D G3DSA:2.60.40.10 1262 1376 1.5E-26 T 28-03-2018 IPR013783 Immunoglobulin-like fold CO689_RS04470 40bfcabcd168adf0b6e7c30ec7a0ddbb 2059 Gene3D G3DSA:2.60.40.10 1142 1261 4.0E-27 T 28-03-2018 IPR013783 Immunoglobulin-like fold CO689_RS04470 40bfcabcd168adf0b6e7c30ec7a0ddbb 2059 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 2020 2053 1.7E-5 T 28-03-2018 CO689_RS04470 40bfcabcd168adf0b6e7c30ec7a0ddbb 2059 SUPERFAMILY SSF117074 1007 1109 1.44E-19 T 28-03-2018 CO689_RS11220 4462df7482e76bc8d3a764c3065e245b 321 ProSitePatterns PS01348 MraY family signature 2. 166 177 - T 28-03-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 CO689_RS11220 4462df7482e76bc8d3a764c3065e245b 321 Pfam PF00953 Glycosyl transferase family 4 77 246 1.3E-39 T 28-03-2018 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193 CO689_RS11220 4462df7482e76bc8d3a764c3065e245b 321 TIGRFAM TIGR00445 mraY: phospho-N-acetylmuramoyl-pentapeptide-transferase 14 316 4.8E-103 T 28-03-2018 IPR003524 Phospho-N-acetylmuramoyl-pentapeptide transferase GO:0008963|GO:0016020 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 CO689_RS11220 4462df7482e76bc8d3a764c3065e245b 321 Hamap MF_00038 Phospho-N-acetylmuramoyl-pentapeptide-transferase [mraY]. 1 320 23.942 T 28-03-2018 IPR003524 Phospho-N-acetylmuramoyl-pentapeptide transferase GO:0008963|GO:0016020 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 CO689_RS11220 4462df7482e76bc8d3a764c3065e245b 321 ProSitePatterns PS01347 MraY family signature 1. 44 56 - T 28-03-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 CO689_RS02205 e75ffae8f9112c19a195c647620fa0e4 346 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 237 256 - T 28-03-2018 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 CO689_RS02205 e75ffae8f9112c19a195c647620fa0e4 346 TIGRFAM TIGR00169 leuB: 3-isopropylmalate dehydrogenase 4 345 8.6E-143 T 28-03-2018 IPR004429 Isopropylmalate dehydrogenase GO:0003862|GO:0005737|GO:0009098|GO:0055114 KEGG: 00290+1.1.1.85|KEGG: 00660+1.1.1.85|MetaCyc: PWY-7396 CO689_RS02205 e75ffae8f9112c19a195c647620fa0e4 346 SUPERFAMILY SSF53659 1 346 9.72E-117 T 28-03-2018 CO689_RS02205 e75ffae8f9112c19a195c647620fa0e4 346 Hamap MF_01033 3-isopropylmalate dehydrogenase [leuB]. 3 346 46.123 T 28-03-2018 IPR004429 Isopropylmalate dehydrogenase GO:0003862|GO:0005737|GO:0009098|GO:0055114 KEGG: 00290+1.1.1.85|KEGG: 00660+1.1.1.85|MetaCyc: PWY-7396 CO689_RS02205 e75ffae8f9112c19a195c647620fa0e4 346 SMART SM01329 4 342 5.7E-181 T 28-03-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 CO689_RS02205 e75ffae8f9112c19a195c647620fa0e4 346 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 4 342 5.2E-125 T 28-03-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 CO689_RS02205 e75ffae8f9112c19a195c647620fa0e4 346 Gene3D G3DSA:3.40.718.10 1 346 3.7E-122 T 28-03-2018 CO689_RS06580 4f97bd46e14e30e00558ca0455385e2e 226 Pfam PF01965 DJ-1/PfpI family 27 222 2.2E-14 T 28-03-2018 IPR002818 DJ-1/PfpI CO689_RS06580 4f97bd46e14e30e00558ca0455385e2e 226 Gene3D G3DSA:3.40.50.880 1 226 1.0E-50 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CO689_RS06580 4f97bd46e14e30e00558ca0455385e2e 226 SUPERFAMILY SSF52317 1 224 5.09E-70 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CO689_RS11395 4ff3ac32e847e15cdb763437c7feed1f 207 Hamap MF_00328 Guanylate kinase [gmk]. 4 188 36.825 T 28-03-2018 IPR017665 Guanylate kinase GO:0004385|GO:0006163 KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221|Reactome: R-HSA-2161541|Reactome: R-HSA-499943 CO689_RS11395 4ff3ac32e847e15cdb763437c7feed1f 207 Gene3D G3DSA:3.40.50.300 83 189 2.3E-35 T 28-03-2018 CO689_RS11395 4ff3ac32e847e15cdb763437c7feed1f 207 ProSitePatterns PS00856 Guanylate kinase-like signature. 41 58 - T 28-03-2018 IPR020590 Guanylate kinase, conserved site KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221 CO689_RS11395 4ff3ac32e847e15cdb763437c7feed1f 207 SUPERFAMILY SSF52540 3 191 8.89E-68 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CO689_RS11395 4ff3ac32e847e15cdb763437c7feed1f 207 Gene3D G3DSA:3.40.50.300 1 52 8.2E-11 T 28-03-2018 CO689_RS11395 4ff3ac32e847e15cdb763437c7feed1f 207 Gene3D G3DSA:3.30.63.10 53 82 4.0E-24 T 28-03-2018 CO689_RS11395 4ff3ac32e847e15cdb763437c7feed1f 207 Pfam PF00625 Guanylate kinase 8 186 8.9E-51 T 28-03-2018 IPR008145 Guanylate kinase/L-type calcium channel beta subunit CO689_RS11395 4ff3ac32e847e15cdb763437c7feed1f 207 SMART SM00072 5 188 3.9E-68 T 28-03-2018 IPR008145 Guanylate kinase/L-type calcium channel beta subunit CO689_RS11395 4ff3ac32e847e15cdb763437c7feed1f 207 TIGRFAM TIGR03263 guanyl_kin: guanylate kinase 6 185 3.0E-72 T 28-03-2018 IPR017665 Guanylate kinase GO:0004385|GO:0006163 KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221|Reactome: R-HSA-2161541|Reactome: R-HSA-499943 CO689_RS10250 5103f8ea61c69f6491532e8d774313ad 190 Gene3D G3DSA:2.40.320.10 2 190 6.8E-34 T 28-03-2018 CO689_RS10250 5103f8ea61c69f6491532e8d774313ad 190 SUPERFAMILY SSF55154 5 186 6.7E-32 T 28-03-2018 IPR033469 CYTH-like domain Reactome: R-HSA-196819 CO689_RS10250 5103f8ea61c69f6491532e8d774313ad 190 Pfam PF01928 CYTH domain 4 185 4.3E-29 T 28-03-2018 IPR023577 CYTH domain Reactome: R-HSA-196819 CO689_RS10250 5103f8ea61c69f6491532e8d774313ad 190 SMART SM01118 4 188 2.4E-21 T 28-03-2018 IPR023577 CYTH domain Reactome: R-HSA-196819 CO689_RS10250 5103f8ea61c69f6491532e8d774313ad 190 PIRSF PIRSF012526 1 190 4.1E-66 T 28-03-2018 IPR009195 Uncharacterised protein family YjbK CO689_RS12035 d657f320159f26a883b9bbf477de4a8f 444 Pfam PF05598 Transposase domain (DUF772) 52 127 3.1E-21 T 28-03-2018 IPR008490 Transposase InsH, N-terminal CO689_RS12035 d657f320159f26a883b9bbf477de4a8f 444 Pfam PF13751 Transposase DDE domain 321 439 1.9E-22 T 28-03-2018 IPR025668 Transposase DDE domain CO689_RS09510 696aef749c084079d5bd71f9c2856b7c 413 Gene3D G3DSA:3.40.640.10 36 285 1.8E-63 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CO689_RS09510 696aef749c084079d5bd71f9c2856b7c 413 PIRSF PIRSF005572 25 410 7.7E-52 T 28-03-2018 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250 CO689_RS09510 696aef749c084079d5bd71f9c2856b7c 413 SUPERFAMILY SSF53383 8 405 5.92E-130 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CO689_RS09510 696aef749c084079d5bd71f9c2856b7c 413 Pfam PF00266 Aminotransferase class-V 29 398 8.5E-163 T 28-03-2018 IPR000192 Aminotransferase class V domain CO689_RS09510 696aef749c084079d5bd71f9c2856b7c 413 TIGRFAM TIGR01979 sufS: cysteine desulfurase, SufS family 10 410 1.2E-186 T 28-03-2018 IPR010970 Cysteine desulfurase, SufS GO:0006534|GO:0030170|GO:0031071 KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250 CO689_RS09510 696aef749c084079d5bd71f9c2856b7c 413 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 220 239 - T 28-03-2018 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site CO689_RS09510 696aef749c084079d5bd71f9c2856b7c 413 Gene3D G3DSA:3.90.1150.10 286 411 1.2E-43 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CO689_RS08835 04a7332abca49f98b64f0b0269e400f8 462 SMART SM01091 354 432 7.9E-11 T 28-03-2018 IPR005170 Transporter-associated domain CO689_RS08835 04a7332abca49f98b64f0b0269e400f8 462 Pfam PF03471 Transporter associated domain 355 429 7.6E-12 T 28-03-2018 IPR005170 Transporter-associated domain CO689_RS08835 04a7332abca49f98b64f0b0269e400f8 462 SUPERFAMILY SSF56176 352 438 4.91E-13 T 28-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CO689_RS08835 04a7332abca49f98b64f0b0269e400f8 462 Pfam PF00571 CBS domain 291 338 6.8E-7 T 28-03-2018 IPR000644 CBS domain CO689_RS08835 04a7332abca49f98b64f0b0269e400f8 462 Pfam PF00571 CBS domain 219 273 8.6E-5 T 28-03-2018 IPR000644 CBS domain CO689_RS08835 04a7332abca49f98b64f0b0269e400f8 462 Gene3D G3DSA:3.30.465.10 346 430 2.0E-13 T 28-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CO689_RS08835 04a7332abca49f98b64f0b0269e400f8 462 SUPERFAMILY SSF54631 207 347 8.21E-30 T 28-03-2018 CO689_RS08835 04a7332abca49f98b64f0b0269e400f8 462 Pfam PF01595 Domain of unknown function DUF21 10 203 1.8E-51 T 28-03-2018 IPR002550 Domain of unknown function DUF21 CO689_RS08835 04a7332abca49f98b64f0b0269e400f8 462 Gene3D G3DSA:3.10.580.10 197 345 4.0E-31 T 28-03-2018 CO689_RS01975 c09c326f091e30086f65dc812d2d40be 431 Gene3D G3DSA:3.90.1150.10 16 101 0.04 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CO689_RS01975 c09c326f091e30086f65dc812d2d40be 431 Gene3D G3DSA:3.90.1150.10 255 431 3.5E-20 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CO689_RS01975 c09c326f091e30086f65dc812d2d40be 431 Pfam PF00155 Aminotransferase class I and II 73 422 5.6E-30 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CO689_RS01975 c09c326f091e30086f65dc812d2d40be 431 Gene3D G3DSA:3.40.640.10 102 254 8.8E-10 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CO689_RS01975 c09c326f091e30086f65dc812d2d40be 431 SUPERFAMILY SSF53383 29 422 1.67E-55 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CO689_RS07290 f947ff17fbab8fc45c859a6371970d60 616 Gene3D G3DSA:2.40.30.10 236 456 2.0E-46 T 28-03-2018 CO689_RS07290 f947ff17fbab8fc45c859a6371970d60 616 PIRSF PIRSF000207 4 616 1.7E-262 T 28-03-2018 IPR010199 Sulphite reductase [NADPH] flavoprotein, alpha chain GO:0000103|GO:0004783|GO:0010181|GO:0019344|GO:0050660|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CO689_RS07290 f947ff17fbab8fc45c859a6371970d60 616 Pfam PF00258 Flavodoxin 81 208 3.2E-32 T 28-03-2018 IPR008254 Flavodoxin/nitric oxide synthase GO:0010181 CO689_RS07290 f947ff17fbab8fc45c859a6371970d60 616 TIGRFAM TIGR01931 cysJ: sulfite reductase [NADPH] flavoprotein, alpha-component 11 616 2.4E-240 T 28-03-2018 IPR010199 Sulphite reductase [NADPH] flavoprotein, alpha chain GO:0000103|GO:0004783|GO:0010181|GO:0019344|GO:0050660|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CO689_RS07290 f947ff17fbab8fc45c859a6371970d60 616 Pfam PF00175 Oxidoreductase NAD-binding domain 474 580 3.5E-18 T 28-03-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 CO689_RS07290 f947ff17fbab8fc45c859a6371970d60 616 SUPERFAMILY SSF52218 76 222 2.72E-49 T 28-03-2018 IPR029039 Flavoprotein-like domain CO689_RS07290 f947ff17fbab8fc45c859a6371970d60 616 Gene3D G3DSA:3.40.50.360 43 235 5.5E-44 T 28-03-2018 IPR029039 Flavoprotein-like domain CO689_RS07290 f947ff17fbab8fc45c859a6371970d60 616 SUPERFAMILY SSF63380 243 462 1.4E-59 T 28-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 CO689_RS07290 f947ff17fbab8fc45c859a6371970d60 616 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 473 492 3.5E-28 T 28-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CO689_RS07290 f947ff17fbab8fc45c859a6371970d60 616 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 542 558 3.5E-28 T 28-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CO689_RS07290 f947ff17fbab8fc45c859a6371970d60 616 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 436 445 3.5E-28 T 28-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CO689_RS07290 f947ff17fbab8fc45c859a6371970d60 616 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 511 522 3.5E-28 T 28-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CO689_RS07290 f947ff17fbab8fc45c859a6371970d60 616 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 284 294 3.5E-28 T 28-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CO689_RS07290 f947ff17fbab8fc45c859a6371970d60 616 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 498 507 3.5E-28 T 28-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CO689_RS07290 f947ff17fbab8fc45c859a6371970d60 616 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 565 573 3.5E-28 T 28-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CO689_RS07290 f947ff17fbab8fc45c859a6371970d60 616 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 403 410 3.5E-28 T 28-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CO689_RS07290 f947ff17fbab8fc45c859a6371970d60 616 Gene3D G3DSA:3.40.50.80 470 616 3.4E-37 T 28-03-2018 CO689_RS07290 f947ff17fbab8fc45c859a6371970d60 616 PRINTS PR00369 Flavodoxin signature 80 93 5.6E-14 T 28-03-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 CO689_RS07290 f947ff17fbab8fc45c859a6371970d60 616 PRINTS PR00369 Flavodoxin signature 128 139 5.6E-14 T 28-03-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 CO689_RS07290 f947ff17fbab8fc45c859a6371970d60 616 PRINTS PR00369 Flavodoxin signature 160 170 5.6E-14 T 28-03-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 CO689_RS07290 f947ff17fbab8fc45c859a6371970d60 616 PRINTS PR00369 Flavodoxin signature 184 203 5.6E-14 T 28-03-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 CO689_RS07290 f947ff17fbab8fc45c859a6371970d60 616 SUPERFAMILY SSF52343 461 616 4.71E-49 T 28-03-2018 CO689_RS07290 f947ff17fbab8fc45c859a6371970d60 616 Pfam PF00667 FAD binding domain 248 439 4.3E-26 T 28-03-2018 IPR003097 FAD-binding, type 1 GO:0016491|GO:0055114 CO689_RS12415 3b2ec06385351989c6f31fe38a8af64a 297 Gene3D G3DSA:3.40.50.300 36 295 1.7E-59 T 28-03-2018 CO689_RS12415 3b2ec06385351989c6f31fe38a8af64a 297 SUPERFAMILY SSF52540 44 284 6.71E-59 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CO689_RS12415 3b2ec06385351989c6f31fe38a8af64a 297 SMART SM00382 75 268 1.0E-8 T 28-03-2018 IPR003593 AAA+ ATPase domain CO689_RS12415 3b2ec06385351989c6f31fe38a8af64a 297 Pfam PF00005 ABC transporter 66 222 1.2E-32 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CO689_RS12415 3b2ec06385351989c6f31fe38a8af64a 297 TIGRFAM TIGR00972 3a0107s01c2: phosphate ABC transporter, ATP-binding protein 51 297 2.9E-126 T 28-03-2018 IPR005670 Phosphate transport system permease protein 1 GO:0005315|GO:0016020|GO:0035435 CO689_RS12415 3b2ec06385351989c6f31fe38a8af64a 297 ProSitePatterns PS00211 ABC transporters family signature. 194 208 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CO689_RS02285 7fe26723bc8953866a5564b3c7df2e91 384 ProSitePatterns PS00395 Alanine racemase pyridoxal-phosphate attachment site. 37 46 - T 28-03-2018 IPR020622 Alanine racemase, pyridoxal-phosphate attachment site KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CO689_RS02285 7fe26723bc8953866a5564b3c7df2e91 384 PRINTS PR00992 Alanine racemase signature 31 47 2.4E-58 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CO689_RS02285 7fe26723bc8953866a5564b3c7df2e91 384 PRINTS PR00992 Alanine racemase signature 67 85 2.4E-58 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CO689_RS02285 7fe26723bc8953866a5564b3c7df2e91 384 PRINTS PR00992 Alanine racemase signature 164 175 2.4E-58 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CO689_RS02285 7fe26723bc8953866a5564b3c7df2e91 384 PRINTS PR00992 Alanine racemase signature 353 366 2.4E-58 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CO689_RS02285 7fe26723bc8953866a5564b3c7df2e91 384 PRINTS PR00992 Alanine racemase signature 202 229 2.4E-58 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CO689_RS02285 7fe26723bc8953866a5564b3c7df2e91 384 PRINTS PR00992 Alanine racemase signature 260 275 2.4E-58 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CO689_RS02285 7fe26723bc8953866a5564b3c7df2e91 384 PRINTS PR00992 Alanine racemase signature 297 314 2.4E-58 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CO689_RS02285 7fe26723bc8953866a5564b3c7df2e91 384 PRINTS PR00992 Alanine racemase signature 277 292 2.4E-58 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CO689_RS02285 7fe26723bc8953866a5564b3c7df2e91 384 PRINTS PR00992 Alanine racemase signature 129 141 2.4E-58 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CO689_RS02285 7fe26723bc8953866a5564b3c7df2e91 384 SMART SM01005 244 371 2.8E-49 T 28-03-2018 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CO689_RS02285 7fe26723bc8953866a5564b3c7df2e91 384 TIGRFAM TIGR00492 alr: alanine racemase 8 370 2.7E-101 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CO689_RS02285 7fe26723bc8953866a5564b3c7df2e91 384 Gene3D G3DSA:3.20.20.10 6 226 9.3E-45 T 28-03-2018 IPR029066 PLP-binding barrel CO689_RS02285 7fe26723bc8953866a5564b3c7df2e91 384 Pfam PF00842 Alanine racemase, C-terminal domain 247 370 1.4E-39 T 28-03-2018 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CO689_RS02285 7fe26723bc8953866a5564b3c7df2e91 384 Gene3D G3DSA:2.40.37.10 227 379 5.1E-50 T 28-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 CO689_RS02285 7fe26723bc8953866a5564b3c7df2e91 384 SUPERFAMILY SSF50621 239 375 1.29E-41 T 28-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 CO689_RS02285 7fe26723bc8953866a5564b3c7df2e91 384 Pfam PF01168 Alanine racemase, N-terminal domain 13 229 1.0E-65 T 28-03-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CO689_RS02285 7fe26723bc8953866a5564b3c7df2e91 384 SUPERFAMILY SSF51419 13 233 1.1E-63 T 28-03-2018 IPR029066 PLP-binding barrel CO689_RS02285 7fe26723bc8953866a5564b3c7df2e91 384 Hamap MF_01201 Alanine racemase. 6 371 31.649 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CO689_RS07925 faf1250869229171aee81e56db0118c6 161 Pfam PF13673 Acetyltransferase (GNAT) domain 33 146 2.1E-14 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CO689_RS07925 faf1250869229171aee81e56db0118c6 161 Gene3D G3DSA:3.40.630.30 2 152 3.4E-17 T 28-03-2018 CO689_RS07925 faf1250869229171aee81e56db0118c6 161 SUPERFAMILY SSF55729 5 146 1.69E-20 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CO689_RS04335 5ed7273fb400ff2e5f02169e7efa2030 595 Pfam PF00005 ABC transporter 352 500 6.5E-28 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CO689_RS04335 5ed7273fb400ff2e5f02169e7efa2030 595 Pfam PF00664 ABC transporter transmembrane region 21 291 1.6E-43 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CO689_RS04335 5ed7273fb400ff2e5f02169e7efa2030 595 SUPERFAMILY SSF52540 331 573 1.2E-77 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CO689_RS04335 5ed7273fb400ff2e5f02169e7efa2030 595 SUPERFAMILY SSF90123 7 320 1.96E-71 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CO689_RS04335 5ed7273fb400ff2e5f02169e7efa2030 595 Gene3D G3DSA:1.20.1560.10 2 323 2.4E-59 T 28-03-2018 CO689_RS04335 5ed7273fb400ff2e5f02169e7efa2030 595 Gene3D G3DSA:3.40.50.300 330 578 1.5E-66 T 28-03-2018 CO689_RS04335 5ed7273fb400ff2e5f02169e7efa2030 595 SMART SM00382 361 548 8.0E-8 T 28-03-2018 IPR003593 AAA+ ATPase domain CO689_RS04335 5ed7273fb400ff2e5f02169e7efa2030 595 ProSitePatterns PS00211 ABC transporters family signature. 474 488 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CO689_RS04410 447635b03bc9d2ac308f459e382cfce2 186 Pfam PF13302 Acetyltransferase (GNAT) domain 22 152 1.4E-17 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CO689_RS04410 447635b03bc9d2ac308f459e382cfce2 186 SUPERFAMILY SSF55729 8 177 1.61E-35 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CO689_RS04410 447635b03bc9d2ac308f459e382cfce2 186 Gene3D G3DSA:3.40.630.30 9 184 7.1E-23 T 28-03-2018 CO689_RS03250 6411117916f92af020c0ff5d418ed65a 201 Pfam PF00196 Bacterial regulatory proteins, luxR family 139 191 3.1E-13 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CO689_RS03250 6411117916f92af020c0ff5d418ed65a 201 SMART SM00421 137 194 5.7E-15 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CO689_RS03250 6411117916f92af020c0ff5d418ed65a 201 SUPERFAMILY SSF52172 1 131 1.2E-28 T 28-03-2018 IPR011006 CheY-like superfamily CO689_RS03250 6411117916f92af020c0ff5d418ed65a 201 Gene3D G3DSA:3.40.50.2300 1 137 7.3E-31 T 28-03-2018 CO689_RS03250 6411117916f92af020c0ff5d418ed65a 201 SUPERFAMILY SSF46894 127 200 6.12E-16 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CO689_RS03250 6411117916f92af020c0ff5d418ed65a 201 Pfam PF00072 Response regulator receiver domain 4 114 2.4E-24 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CO689_RS03250 6411117916f92af020c0ff5d418ed65a 201 Gene3D G3DSA:1.10.10.10 138 200 4.7E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS03250 6411117916f92af020c0ff5d418ed65a 201 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 170 182 4.5E-8 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CO689_RS03250 6411117916f92af020c0ff5d418ed65a 201 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 154 170 4.5E-8 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CO689_RS03250 6411117916f92af020c0ff5d418ed65a 201 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 140 154 4.5E-8 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CO689_RS03250 6411117916f92af020c0ff5d418ed65a 201 SMART SM00448 2 115 1.1E-23 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CO689_RS06765 3a5236a179a1d3aa9280debd70abc5b7 115 Pfam PF13411 MerR HTH family regulatory protein 6 68 3.4E-14 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CO689_RS06765 3a5236a179a1d3aa9280debd70abc5b7 115 SUPERFAMILY SSF46955 3 109 7.33E-23 T 28-03-2018 IPR009061 Putative DNA-binding domain CO689_RS06765 3a5236a179a1d3aa9280debd70abc5b7 115 Gene3D G3DSA:1.10.1660.10 59 115 1.0E-6 T 28-03-2018 CO689_RS06765 3a5236a179a1d3aa9280debd70abc5b7 115 SMART SM00422 4 73 8.5E-14 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CO689_RS06765 3a5236a179a1d3aa9280debd70abc5b7 115 Gene3D G3DSA:1.10.1660.10 1 58 4.4E-16 T 28-03-2018 CO689_RS10260 c4937728c01f14116a883da6a68a46d9 211 SMART SM00954 43 164 1.7E-39 T 28-03-2018 IPR007685 RelA/SpoT GO:0015969 CO689_RS10260 c4937728c01f14116a883da6a68a46d9 211 Pfam PF04607 Region found in RelA / SpoT proteins 43 162 6.8E-37 T 28-03-2018 IPR007685 RelA/SpoT GO:0015969 CO689_RS10260 c4937728c01f14116a883da6a68a46d9 211 Gene3D G3DSA:3.30.460.10 1 145 3.0E-36 T 28-03-2018 CO689_RS10260 c4937728c01f14116a883da6a68a46d9 211 Gene3D G3DSA:1.10.287.860 147 195 2.9E-20 T 28-03-2018 CO689_RS10260 c4937728c01f14116a883da6a68a46d9 211 SUPERFAMILY SSF81301 3 199 6.21E-60 T 28-03-2018 CO689_RS11100 a27c285585392de69204d84aa76fcfec 598 ProSitePatterns PS00504 Fumarate reductase / succinate dehydrogenase FAD-binding site. 39 48 - T 28-03-2018 IPR003952 Fumarate reductase/succinate dehydrogenase, FAD-binding site GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CO689_RS11100 a27c285585392de69204d84aa76fcfec 598 PIRSF PIRSF000171 1 240 7.6E-20 T 28-03-2018 CO689_RS11100 a27c285585392de69204d84aa76fcfec 598 PIRSF PIRSF000171 341 572 7.7E-15 T 28-03-2018 CO689_RS11100 a27c285585392de69204d84aa76fcfec 598 Pfam PF02910 Fumarate reductase flavoprotein C-term 452 579 4.0E-40 T 28-03-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CO689_RS11100 a27c285585392de69204d84aa76fcfec 598 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 5 27 7.4E-5 T 28-03-2018 CO689_RS11100 a27c285585392de69204d84aa76fcfec 598 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 396 411 7.4E-5 T 28-03-2018 CO689_RS11100 a27c285585392de69204d84aa76fcfec 598 TIGRFAM TIGR01811 sdhA_Bsu: succinate dehydrogenase or fumarate reductase, flavoprotein subunit 6 579 1.2E-279 T 28-03-2018 IPR011280 Succinate dehydrogenase/fumarate reductase flavoprotein subunit, low-GC Gram-positive bacteria KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279 CO689_RS11100 a27c285585392de69204d84aa76fcfec 598 Gene3D G3DSA:3.50.50.60 2 445 9.0E-52 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CO689_RS11100 a27c285585392de69204d84aa76fcfec 598 SUPERFAMILY SSF56425 231 353 2.09E-31 T 28-03-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 CO689_RS11100 a27c285585392de69204d84aa76fcfec 598 Gene3D G3DSA:1.20.58.100 446 546 4.7E-24 T 28-03-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CO689_RS11100 a27c285585392de69204d84aa76fcfec 598 SUPERFAMILY SSF46977 444 580 6.15E-43 T 28-03-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CO689_RS11100 a27c285585392de69204d84aa76fcfec 598 SUPERFAMILY SSF51905 3 247 1.0E-61 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CO689_RS11100 a27c285585392de69204d84aa76fcfec 598 SUPERFAMILY SSF51905 357 425 1.0E-61 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CO689_RS11100 a27c285585392de69204d84aa76fcfec 598 Gene3D G3DSA:4.10.80.40 547 579 4.5E-4 T 28-03-2018 CO689_RS11100 a27c285585392de69204d84aa76fcfec 598 Pfam PF00890 FAD binding domain 6 392 4.5E-84 T 28-03-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 CO689_RS11100 a27c285585392de69204d84aa76fcfec 598 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 2.2E-6 T 28-03-2018 CO689_RS11100 a27c285585392de69204d84aa76fcfec 598 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 356 378 2.2E-6 T 28-03-2018 CO689_RS12860 5a4609905069a29379fafcd5a2276a2e 585 SMART SM00388 356 423 3.7E-19 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CO689_RS12860 5a4609905069a29379fafcd5a2276a2e 585 Gene3D G3DSA:1.10.287.130 362 419 9.7E-17 T 28-03-2018 CO689_RS12860 5a4609905069a29379fafcd5a2276a2e 585 SUPERFAMILY SSF158472 195 245 2.88E-10 T 28-03-2018 CO689_RS12860 5a4609905069a29379fafcd5a2276a2e 585 SUPERFAMILY SSF55785 240 348 5.02E-5 T 28-03-2018 IPR000014 PAS domain CO689_RS12860 5a4609905069a29379fafcd5a2276a2e 585 PRINTS PR00344 Bacterial sensor protein C-terminal signature 524 534 9.6E-16 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CO689_RS12860 5a4609905069a29379fafcd5a2276a2e 585 PRINTS PR00344 Bacterial sensor protein C-terminal signature 541 559 9.6E-16 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CO689_RS12860 5a4609905069a29379fafcd5a2276a2e 585 PRINTS PR00344 Bacterial sensor protein C-terminal signature 506 520 9.6E-16 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CO689_RS12860 5a4609905069a29379fafcd5a2276a2e 585 PRINTS PR00344 Bacterial sensor protein C-terminal signature 565 578 9.6E-16 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CO689_RS12860 5a4609905069a29379fafcd5a2276a2e 585 Gene3D G3DSA:3.30.450.20 32 168 2.5E-5 T 28-03-2018 CO689_RS12860 5a4609905069a29379fafcd5a2276a2e 585 SMART SM00304 194 246 8.0E-11 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CO689_RS12860 5a4609905069a29379fafcd5a2276a2e 585 Pfam PF00512 His Kinase A (phospho-acceptor) domain 356 422 2.1E-16 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CO689_RS12860 5a4609905069a29379fafcd5a2276a2e 585 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 470 579 1.1E-24 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CO689_RS12860 5a4609905069a29379fafcd5a2276a2e 585 SUPERFAMILY SSF55874 412 579 1.07E-44 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CO689_RS12860 5a4609905069a29379fafcd5a2276a2e 585 Pfam PF00672 HAMP domain 195 243 2.1E-11 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CO689_RS12860 5a4609905069a29379fafcd5a2276a2e 585 SMART SM00387 469 581 6.5E-36 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CO689_RS12860 5a4609905069a29379fafcd5a2276a2e 585 Gene3D G3DSA:3.30.450.20 250 361 5.0E-5 T 28-03-2018 CO689_RS12860 5a4609905069a29379fafcd5a2276a2e 585 Gene3D G3DSA:3.30.565.10 437 585 1.9E-41 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CO689_RS12860 5a4609905069a29379fafcd5a2276a2e 585 SUPERFAMILY SSF47384 341 423 6.47E-19 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CO689_RS06685 c10248e93130077586681f51903041d6 562 Pfam PF07510 Protein of unknown function (DUF1524) 419 553 4.7E-28 T 28-03-2018 IPR011089 Domain of unknown function DUF1524 CO689_RS06685 c10248e93130077586681f51903041d6 562 Pfam PF03235 Protein of unknown function DUF262 17 231 4.7E-27 T 28-03-2018 IPR004919 Domain of unknown function DUF262 CO689_RS01730 fca238b4e4e095b8943e989a8ae97bb5 347 Gene3D G3DSA:3.30.565.10 210 347 4.9E-26 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CO689_RS01730 fca238b4e4e095b8943e989a8ae97bb5 347 SMART SM00387 248 341 1.2E-6 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CO689_RS01730 fca238b4e4e095b8943e989a8ae97bb5 347 PIRSF PIRSF037431 2 347 2.3E-120 T 28-03-2018 IPR017202 Sensor histidine kinase LiaS/VraS GO:0000155|GO:0000160|GO:0004673|GO:0016021 CO689_RS01730 fca238b4e4e095b8943e989a8ae97bb5 347 SUPERFAMILY SSF55874 220 338 1.7E-16 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CO689_RS01730 fca238b4e4e095b8943e989a8ae97bb5 347 Pfam PF07730 Histidine kinase 147 210 1.0E-16 T 28-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 CO689_RS01730 fca238b4e4e095b8943e989a8ae97bb5 347 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 249 340 1.9E-5 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CO689_RS01205 db1c19b694e052163b85d6ee3adec876 163 Pfam PF00293 NUDIX domain 27 103 3.2E-12 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 CO689_RS01205 db1c19b694e052163b85d6ee3adec876 163 PRINTS PR00502 NUDIX hydrolase family signature 47 61 4.8E-6 T 28-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CO689_RS01205 db1c19b694e052163b85d6ee3adec876 163 PRINTS PR00502 NUDIX hydrolase family signature 61 76 4.8E-6 T 28-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CO689_RS01205 db1c19b694e052163b85d6ee3adec876 163 Gene3D G3DSA:3.90.79.10 1 150 6.8E-19 T 28-03-2018 CO689_RS01205 db1c19b694e052163b85d6ee3adec876 163 TIGRFAM TIGR02705 nudix_YtkD: nucleoside triphosphatase YtkD 4 156 8.7E-54 T 28-03-2018 IPR014078 Nucleoside triphosphatase YtkD MetaCyc: PWY-6502 CO689_RS01205 db1c19b694e052163b85d6ee3adec876 163 ProSitePatterns PS00893 Nudix box signature. 52 73 - T 28-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 CO689_RS01205 db1c19b694e052163b85d6ee3adec876 163 SUPERFAMILY SSF55811 27 119 7.04E-19 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CO689_RS13505 306126d496800d11501852b9161b58fb 150 Gene3D G3DSA:3.50.80.10 1 150 7.4E-53 T 28-03-2018 IPR023509 D-Tyr tRNAtyr deacylase-like domain CO689_RS13505 306126d496800d11501852b9161b58fb 150 Hamap MF_00518 D-aminoacyl-tRNA deacylase [dtd]. 1 144 31.809 T 28-03-2018 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0002161|GO:0005737|GO:0051499 CO689_RS13505 306126d496800d11501852b9161b58fb 150 Pfam PF02580 D-Tyr-tRNA(Tyr) deacylase 2 143 1.0E-52 T 28-03-2018 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0002161|GO:0005737|GO:0051499 CO689_RS13505 306126d496800d11501852b9161b58fb 150 SUPERFAMILY SSF69500 1 143 1.57E-52 T 28-03-2018 IPR023509 D-Tyr tRNAtyr deacylase-like domain CO689_RS13505 306126d496800d11501852b9161b58fb 150 TIGRFAM TIGR00256 TIGR00256: D-tyrosyl-tRNA(Tyr) deacylase 1 144 4.4E-53 T 28-03-2018 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0002161|GO:0005737|GO:0051499 CO689_RS01075 a21c51bcea01878e47b1cc17e835fc31 804 Pfam PF13603 Leucyl-tRNA synthetase, Domain 2 219 398 3.0E-68 T 28-03-2018 IPR025709 Leucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 KEGG: 00970+6.1.1.4 CO689_RS01075 a21c51bcea01878e47b1cc17e835fc31 804 SUPERFAMILY SSF52374 411 624 1.96E-143 T 28-03-2018 CO689_RS01075 a21c51bcea01878e47b1cc17e835fc31 804 SUPERFAMILY SSF52374 3 224 1.96E-143 T 28-03-2018 CO689_RS01075 a21c51bcea01878e47b1cc17e835fc31 804 Pfam PF08264 Anticodon-binding domain of tRNA 650 766 1.9E-20 T 28-03-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 CO689_RS01075 a21c51bcea01878e47b1cc17e835fc31 804 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 412 607 5.3E-19 T 28-03-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 CO689_RS01075 a21c51bcea01878e47b1cc17e835fc31 804 PRINTS PR00985 Leucyl-tRNA synthetase signature 184 197 2.1E-56 T 28-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 CO689_RS01075 a21c51bcea01878e47b1cc17e835fc31 804 PRINTS PR00985 Leucyl-tRNA synthetase signature 557 567 2.1E-56 T 28-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 CO689_RS01075 a21c51bcea01878e47b1cc17e835fc31 804 PRINTS PR00985 Leucyl-tRNA synthetase signature 524 546 2.1E-56 T 28-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 CO689_RS01075 a21c51bcea01878e47b1cc17e835fc31 804 PRINTS PR00985 Leucyl-tRNA synthetase signature 126 143 2.1E-56 T 28-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 CO689_RS01075 a21c51bcea01878e47b1cc17e835fc31 804 PRINTS PR00985 Leucyl-tRNA synthetase signature 152 168 2.1E-56 T 28-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 CO689_RS01075 a21c51bcea01878e47b1cc17e835fc31 804 PRINTS PR00985 Leucyl-tRNA synthetase signature 485 503 2.1E-56 T 28-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 CO689_RS01075 a21c51bcea01878e47b1cc17e835fc31 804 PRINTS PR00985 Leucyl-tRNA synthetase signature 213 232 2.1E-56 T 28-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 CO689_RS01075 a21c51bcea01878e47b1cc17e835fc31 804 Gene3D G3DSA:3.40.50.620 1 321 2.2E-101 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CO689_RS01075 a21c51bcea01878e47b1cc17e835fc31 804 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 42 52 - T 28-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 CO689_RS01075 a21c51bcea01878e47b1cc17e835fc31 804 SUPERFAMILY SSF50677 224 410 1.57E-56 T 28-03-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 CO689_RS01075 a21c51bcea01878e47b1cc17e835fc31 804 Pfam PF09334 tRNA synthetases class I (M) 39 170 2.6E-18 T 28-03-2018 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 CO689_RS01075 a21c51bcea01878e47b1cc17e835fc31 804 Gene3D G3DSA:3.40.50.620 381 564 4.0E-54 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CO689_RS01075 a21c51bcea01878e47b1cc17e835fc31 804 Hamap MF_00049_B Leucine--tRNA ligase [leuS]. 2 803 23.147 T 28-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 CO689_RS01075 a21c51bcea01878e47b1cc17e835fc31 804 TIGRFAM TIGR00396 leuS_bact: leucine--tRNA ligase 4 804 0.0 T 28-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 CO689_RS01075 a21c51bcea01878e47b1cc17e835fc31 804 SUPERFAMILY SSF47323 619 803 1.01E-38 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CO689_RS01075 a21c51bcea01878e47b1cc17e835fc31 804 Gene3D G3DSA:1.10.730.10 565 803 3.9E-62 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CO689_RS07015 55b9e4ffc2870eb5842212bbda14b8fd 74 SUPERFAMILY SSF55174 9 67 5.21E-17 T 28-03-2018 CO689_RS07015 55b9e4ffc2870eb5842212bbda14b8fd 74 TIGRFAM TIGR02988 YaaA_near_RecF: S4 domain protein YaaA 5 62 1.8E-27 T 28-03-2018 IPR014330 RNA-binding S4-related,YaaA CO689_RS07015 55b9e4ffc2870eb5842212bbda14b8fd 74 Pfam PF13275 S4 domain 11 66 1.4E-24 T 28-03-2018 CO689_RS07015 55b9e4ffc2870eb5842212bbda14b8fd 74 Gene3D G3DSA:3.10.290.10 2 69 7.2E-11 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CO689_RS10905 580e14a61f7c1ea3194e6d3a513aea52 357 Pfam PF13416 Bacterial extracellular solute-binding protein 49 321 5.3E-37 T 28-03-2018 CO689_RS10905 580e14a61f7c1ea3194e6d3a513aea52 357 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 99 112 1.3E-60 T 28-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 CO689_RS10905 580e14a61f7c1ea3194e6d3a513aea52 357 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 40 56 1.3E-60 T 28-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 CO689_RS10905 580e14a61f7c1ea3194e6d3a513aea52 357 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 156 170 1.3E-60 T 28-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 CO689_RS10905 580e14a61f7c1ea3194e6d3a513aea52 357 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 56 77 1.3E-60 T 28-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 CO689_RS10905 580e14a61f7c1ea3194e6d3a513aea52 357 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 300 326 1.3E-60 T 28-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 CO689_RS10905 580e14a61f7c1ea3194e6d3a513aea52 357 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 83 97 1.3E-60 T 28-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 CO689_RS10905 580e14a61f7c1ea3194e6d3a513aea52 357 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 130 146 1.3E-60 T 28-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 CO689_RS10905 580e14a61f7c1ea3194e6d3a513aea52 357 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 174 193 1.3E-60 T 28-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 CO689_RS10905 580e14a61f7c1ea3194e6d3a513aea52 357 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 255 274 1.3E-60 T 28-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 CO689_RS10905 580e14a61f7c1ea3194e6d3a513aea52 357 PIRSF PIRSF019574 1 356 7.2E-134 T 28-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 CO689_RS10905 580e14a61f7c1ea3194e6d3a513aea52 357 Gene3D G3DSA:3.40.190.10 149 307 1.9E-37 T 28-03-2018 CO689_RS10905 580e14a61f7c1ea3194e6d3a513aea52 357 Gene3D G3DSA:3.40.190.10 22 148 8.9E-23 T 28-03-2018 CO689_RS10905 580e14a61f7c1ea3194e6d3a513aea52 357 SUPERFAMILY SSF53850 34 353 1.68E-89 T 28-03-2018 CO689_RS06755 de67dacae8e82f9dce4b1a8cc259c000 221 Gene3D G3DSA:3.40.50.720 2 218 8.2E-30 T 28-03-2018 CO689_RS06755 de67dacae8e82f9dce4b1a8cc259c000 221 SUPERFAMILY SSF51735 1 208 9.83E-35 T 28-03-2018 IPR016040 NAD(P)-binding domain CO689_RS06755 de67dacae8e82f9dce4b1a8cc259c000 221 Pfam PF13460 NAD(P)H-binding 7 194 1.5E-41 T 28-03-2018 IPR016040 NAD(P)-binding domain CO689_RS08035 3847cdb37def14dd79e1dd94c9cc7503 122 Gene3D G3DSA:1.20.5.710 2 51 4.2E-17 T 28-03-2018 CO689_RS08035 3847cdb37def14dd79e1dd94c9cc7503 122 Pfam PF00542 Ribosomal protein L7/L12 C-terminal domain 56 122 6.1E-29 T 28-03-2018 IPR013823 Ribosomal protein L7/L12, C-terminal GO:0003735|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CO689_RS08035 3847cdb37def14dd79e1dd94c9cc7503 122 Hamap MF_00368 50S ribosomal protein L7/L12 [rplL]. 1 122 24.74 T 28-03-2018 IPR000206 Ribosomal protein L7/L12 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CO689_RS08035 3847cdb37def14dd79e1dd94c9cc7503 122 TIGRFAM TIGR00855 L12: ribosomal protein bL12 1 122 2.1E-47 T 28-03-2018 IPR000206 Ribosomal protein L7/L12 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CO689_RS08035 3847cdb37def14dd79e1dd94c9cc7503 122 ProDom PD001326 RIBOSOMAL L7/L12 50S RIBONUCLEOPROTEIN CHLOROPLAST L12 PLASTID DIRECT SEQUENCING PEPTIDE 57 122 3.0E-16 T 28-03-2018 IPR013823 Ribosomal protein L7/L12, C-terminal GO:0003735|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CO689_RS08035 3847cdb37def14dd79e1dd94c9cc7503 122 Gene3D G3DSA:3.30.1390.10 52 122 4.6E-29 T 28-03-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like CO689_RS08035 3847cdb37def14dd79e1dd94c9cc7503 122 Pfam PF16320 Ribosomal protein L7/L12 dimerisation domain 5 49 4.5E-21 T 28-03-2018 IPR008932 Ribosomal protein L7/L12, oligomerisation GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CO689_RS08035 3847cdb37def14dd79e1dd94c9cc7503 122 SUPERFAMILY SSF48300 3 58 2.22E-18 T 28-03-2018 IPR008932 Ribosomal protein L7/L12, oligomerisation GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CO689_RS08035 3847cdb37def14dd79e1dd94c9cc7503 122 SUPERFAMILY SSF54736 52 122 2.62E-24 T 28-03-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like CO689_RS08165 d9791653bdc4dab15e7a9e09d23004c7 289 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 4 280 2.1E-61 T 28-03-2018 IPR000150 Cof family GO:0016787 CO689_RS08165 d9791653bdc4dab15e7a9e09d23004c7 289 ProSitePatterns PS01228 Hypothetical cof family signature 1. 4 15 - T 28-03-2018 CO689_RS08165 d9791653bdc4dab15e7a9e09d23004c7 289 SUPERFAMILY SSF56784 1 284 2.51E-69 T 28-03-2018 IPR023214 HAD-like domain CO689_RS08165 d9791653bdc4dab15e7a9e09d23004c7 289 Gene3D G3DSA:3.40.50.1000 1 289 4.4E-40 T 28-03-2018 IPR023214 HAD-like domain CO689_RS08165 d9791653bdc4dab15e7a9e09d23004c7 289 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 4 253 5.5E-28 T 28-03-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 CO689_RS08165 d9791653bdc4dab15e7a9e09d23004c7 289 Pfam PF08282 haloacid dehalogenase-like hydrolase 5 280 2.4E-70 T 28-03-2018 IPR023214 HAD-like domain CO689_RS08165 d9791653bdc4dab15e7a9e09d23004c7 289 ProSitePatterns PS01229 Hypothetical cof family signature 2. 234 256 - T 28-03-2018 CO689_RS03490 0baec182f9f7bd749255402204e567f1 104 Pfam PF00893 Small Multidrug Resistance protein 1 93 8.8E-25 T 28-03-2018 IPR000390 Small multidrug resistance protein family GO:0016021 CO689_RS03490 0baec182f9f7bd749255402204e567f1 104 SUPERFAMILY SSF103481 4 102 3.27E-16 T 28-03-2018 CO689_RS00290 66d4b29b5b603bf01a3df8ddc7cf73f3 132 Gene3D G3DSA:1.10.1660.10 1 57 1.1E-22 T 28-03-2018 CO689_RS00290 66d4b29b5b603bf01a3df8ddc7cf73f3 132 Pfam PF13411 MerR HTH family regulatory protein 3 69 1.5E-19 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CO689_RS00290 66d4b29b5b603bf01a3df8ddc7cf73f3 132 SUPERFAMILY SSF46955 3 129 1.28E-35 T 28-03-2018 IPR009061 Putative DNA-binding domain CO689_RS00290 66d4b29b5b603bf01a3df8ddc7cf73f3 132 Gene3D G3DSA:1.10.1660.10 58 132 9.2E-19 T 28-03-2018 CO689_RS00290 66d4b29b5b603bf01a3df8ddc7cf73f3 132 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 39 59 3.4E-14 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CO689_RS00290 66d4b29b5b603bf01a3df8ddc7cf73f3 132 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 15 28 3.4E-14 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CO689_RS00290 66d4b29b5b603bf01a3df8ddc7cf73f3 132 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 4 15 3.4E-14 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CO689_RS00290 66d4b29b5b603bf01a3df8ddc7cf73f3 132 SMART SM00422 3 72 1.7E-29 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CO689_RS00290 66d4b29b5b603bf01a3df8ddc7cf73f3 132 TIGRFAM TIGR02051 MerR: Hg(II)-responsive transcriptional regulator 4 128 3.6E-52 T 28-03-2018 IPR011794 Hg(II)-responsive transcriptional regulator GO:0003677|GO:0006355|GO:0045340|GO:0046689 CO689_RS06535 8a4b64493679eb1f910f04d1d279b0e9 621 Gene3D G3DSA:1.10.10.10 80 147 0.26 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS06535 8a4b64493679eb1f910f04d1d279b0e9 621 Gene3D G3DSA:3.40.50.2300 381 473 7.1E-13 T 28-03-2018 CO689_RS06535 8a4b64493679eb1f910f04d1d279b0e9 621 Gene3D G3DSA:1.10.10.10 1 65 7.5E-9 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS06535 8a4b64493679eb1f910f04d1d279b0e9 621 Pfam PF08279 HTH domain 4 61 7.0E-8 T 28-03-2018 IPR013196 Helix-turn-helix, type 11 CO689_RS06535 8a4b64493679eb1f910f04d1d279b0e9 621 Pfam PF00874 PRD domain 285 373 3.6E-20 T 28-03-2018 IPR011608 PRD domain GO:0006355 CO689_RS06535 8a4b64493679eb1f910f04d1d279b0e9 621 ProSitePatterns PS00372 PTS EIIA domains phosphorylation site signature 2. 527 543 - T 28-03-2018 IPR002178 PTS EIIA type-2 domain CO689_RS06535 8a4b64493679eb1f910f04d1d279b0e9 621 SUPERFAMILY SSF52794 383 470 8.37E-6 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 CO689_RS06535 8a4b64493679eb1f910f04d1d279b0e9 621 SUPERFAMILY SSF55804 494 599 2.22E-20 T 28-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 CO689_RS06535 8a4b64493679eb1f910f04d1d279b0e9 621 SUPERFAMILY SSF63520 264 378 6.15E-21 T 28-03-2018 IPR011608 PRD domain GO:0006355 CO689_RS06535 8a4b64493679eb1f910f04d1d279b0e9 621 Gene3D G3DSA:3.40.930.10 487 617 2.2E-20 T 28-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 CO689_RS06535 8a4b64493679eb1f910f04d1d279b0e9 621 Gene3D G3DSA:1.10.1790.10 274 378 7.9E-21 T 28-03-2018 IPR011608 PRD domain GO:0006355 CO689_RS06535 8a4b64493679eb1f910f04d1d279b0e9 621 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 494 603 1.1E-19 T 28-03-2018 IPR002178 PTS EIIA type-2 domain CO689_RS13665 de01f28ac3c45b45b16e165ad8664c34 876 SUPERFAMILY SSF46589 810 874 1.31E-17 T 28-03-2018 IPR010978 tRNA-binding arm GO:0000166 CO689_RS13665 de01f28ac3c45b45b16e165ad8664c34 876 Gene3D G3DSA:3.90.740.10 236 433 1.4E-61 T 28-03-2018 CO689_RS13665 de01f28ac3c45b45b16e165ad8664c34 876 Gene3D G3DSA:1.10.287.380 803 873 2.9E-27 T 28-03-2018 IPR019499 Valyl-tRNA synthetase, tRNA-binding arm GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: R-HSA-379716 CO689_RS13665 de01f28ac3c45b45b16e165ad8664c34 876 Hamap MF_02004 Valine--tRNA ligase [valS]. 3 875 16.006 T 28-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 CO689_RS13665 de01f28ac3c45b45b16e165ad8664c34 876 SUPERFAMILY SSF52374 341 570 3.96E-142 T 28-03-2018 CO689_RS13665 de01f28ac3c45b45b16e165ad8664c34 876 SUPERFAMILY SSF52374 2 193 3.96E-142 T 28-03-2018 CO689_RS13665 de01f28ac3c45b45b16e165ad8664c34 876 Gene3D G3DSA:3.90.740.10 191 235 2.9E-13 T 28-03-2018 CO689_RS13665 de01f28ac3c45b45b16e165ad8664c34 876 Pfam PF10458 Valyl tRNA synthetase tRNA binding arm 810 875 1.6E-23 T 28-03-2018 IPR019499 Valyl-tRNA synthetase, tRNA-binding arm GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: R-HSA-379716 CO689_RS13665 de01f28ac3c45b45b16e165ad8664c34 876 Gene3D G3DSA:1.10.730.10 518 743 7.5E-77 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CO689_RS13665 de01f28ac3c45b45b16e165ad8664c34 876 PRINTS PR00986 Valyl-tRNA synthetase signature 346 359 2.7E-36 T 28-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 CO689_RS13665 de01f28ac3c45b45b16e165ad8664c34 876 PRINTS PR00986 Valyl-tRNA synthetase signature 37 48 2.7E-36 T 28-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 CO689_RS13665 de01f28ac3c45b45b16e165ad8664c34 876 PRINTS PR00986 Valyl-tRNA synthetase signature 231 248 2.7E-36 T 28-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 CO689_RS13665 de01f28ac3c45b45b16e165ad8664c34 876 PRINTS PR00986 Valyl-tRNA synthetase signature 472 490 2.7E-36 T 28-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 CO689_RS13665 de01f28ac3c45b45b16e165ad8664c34 876 PRINTS PR00986 Valyl-tRNA synthetase signature 440 461 2.7E-36 T 28-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 CO689_RS13665 de01f28ac3c45b45b16e165ad8664c34 876 SUPERFAMILY SSF50677 192 342 1.44E-60 T 28-03-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 CO689_RS13665 de01f28ac3c45b45b16e165ad8664c34 876 Gene3D G3DSA:3.40.50.620 434 517 5.9E-31 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CO689_RS13665 de01f28ac3c45b45b16e165ad8664c34 876 SUPERFAMILY SSF47323 571 825 1.46E-74 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CO689_RS13665 de01f28ac3c45b45b16e165ad8664c34 876 Pfam PF08264 Anticodon-binding domain of tRNA 604 751 2.3E-43 T 28-03-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 CO689_RS13665 de01f28ac3c45b45b16e165ad8664c34 876 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 16 559 9.4E-215 T 28-03-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 CO689_RS13665 de01f28ac3c45b45b16e165ad8664c34 876 TIGRFAM TIGR00422 valS: valine--tRNA ligase 3 857 0.0 T 28-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 CO689_RS13665 de01f28ac3c45b45b16e165ad8664c34 876 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 44 55 - T 28-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 CO689_RS13665 de01f28ac3c45b45b16e165ad8664c34 876 Gene3D G3DSA:3.40.50.620 17 190 1.5E-28 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CO689_RS12680 ca1f41bda7eb08bcf8ae2b2a48627b87 187 Hamap MF_01575 UPF0398 protein . 2 178 34.689 T 28-03-2018 IPR010697 Protein of unknown function DUF1273 CO689_RS12680 ca1f41bda7eb08bcf8ae2b2a48627b87 187 Pfam PF06908 Protein of unknown function (DUF1273) 6 172 2.5E-68 T 28-03-2018 IPR010697 Protein of unknown function DUF1273 CO689_RS12680 ca1f41bda7eb08bcf8ae2b2a48627b87 187 Gene3D G3DSA:3.40.50.450 1 181 2.4E-31 T 28-03-2018 CO689_RS12680 ca1f41bda7eb08bcf8ae2b2a48627b87 187 SUPERFAMILY SSF102405 3 177 1.46E-61 T 28-03-2018 CO689_RS12680 ca1f41bda7eb08bcf8ae2b2a48627b87 187 PIRSF PIRSF021290 2 180 8.1E-68 T 28-03-2018 IPR010697 Protein of unknown function DUF1273 CO689_RS11105 b48aadb0621ae75662666ab3bd8a807b 269 Gene3D G3DSA:3.10.20.30 13 125 1.0E-23 T 28-03-2018 IPR012675 Beta-grasp domain CO689_RS11105 b48aadb0621ae75662666ab3bd8a807b 269 Pfam PF13085 2Fe-2S iron-sulfur cluster binding domain 22 131 3.8E-27 T 28-03-2018 IPR025192 Succinate dehydogenase/fumarate reductase N-terminal GO:0009055|GO:0051536 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 CO689_RS11105 b48aadb0621ae75662666ab3bd8a807b 269 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 169 180 - T 28-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CO689_RS11105 b48aadb0621ae75662666ab3bd8a807b 269 SUPERFAMILY SSF54292 19 126 6.23E-21 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CO689_RS11105 b48aadb0621ae75662666ab3bd8a807b 269 Pfam PF13183 4Fe-4S dicluster domain 165 240 2.7E-9 T 28-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CO689_RS11105 b48aadb0621ae75662666ab3bd8a807b 269 SUPERFAMILY SSF46548 128 252 3.49E-25 T 28-03-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 CO689_RS11105 b48aadb0621ae75662666ab3bd8a807b 269 Gene3D G3DSA:1.10.1060.10 126 256 5.5E-17 T 28-03-2018 CO689_RS11105 b48aadb0621ae75662666ab3bd8a807b 269 TIGRFAM TIGR00384 dhsB: succinate dehydrogenase and fumarate reductase iron-sulfur protein 25 248 7.1E-40 T 28-03-2018 IPR004489 Succinate dehydrogenase/fumarate reductase iron-sulphur protein GO:0006099|GO:0016491|GO:0055114 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 CO689_RS02340 dcf6b8965fdc7a91bea2d966c2ee8902 730 SUPERFAMILY SSF81665 169 226 9.29E-12 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CO689_RS02340 dcf6b8965fdc7a91bea2d966c2ee8902 730 SUPERFAMILY SSF81665 668 689 9.29E-12 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CO689_RS02340 dcf6b8965fdc7a91bea2d966c2ee8902 730 SUPERFAMILY SSF81665 323 418 9.29E-12 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CO689_RS02340 dcf6b8965fdc7a91bea2d966c2ee8902 730 ProSitePatterns PS01047 Heavy-metal-associated domain. 8 37 - T 28-03-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 CO689_RS02340 dcf6b8965fdc7a91bea2d966c2ee8902 730 Pfam PF00403 Heavy-metal-associated domain 6 66 1.4E-15 T 28-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 CO689_RS02340 dcf6b8965fdc7a91bea2d966c2ee8902 730 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 424 438 1.7E-26 T 28-03-2018 CO689_RS02340 dcf6b8965fdc7a91bea2d966c2ee8902 730 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 545 556 1.7E-26 T 28-03-2018 CO689_RS02340 dcf6b8965fdc7a91bea2d966c2ee8902 730 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 642 654 1.7E-26 T 28-03-2018 CO689_RS02340 dcf6b8965fdc7a91bea2d966c2ee8902 730 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 566 576 1.7E-26 T 28-03-2018 CO689_RS02340 dcf6b8965fdc7a91bea2d966c2ee8902 730 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 272 286 1.7E-26 T 28-03-2018 CO689_RS02340 dcf6b8965fdc7a91bea2d966c2ee8902 730 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 619 638 1.7E-26 T 28-03-2018 CO689_RS02340 dcf6b8965fdc7a91bea2d966c2ee8902 730 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 195 703 6.0E-94 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CO689_RS02340 dcf6b8965fdc7a91bea2d966c2ee8902 730 PRINTS PR00943 Copper-transporting ATPase signature 142 161 4.1E-20 T 28-03-2018 CO689_RS02340 dcf6b8965fdc7a91bea2d966c2ee8902 730 PRINTS PR00943 Copper-transporting ATPase signature 18 32 4.1E-20 T 28-03-2018 CO689_RS02340 dcf6b8965fdc7a91bea2d966c2ee8902 730 PRINTS PR00943 Copper-transporting ATPase signature 596 613 4.1E-20 T 28-03-2018 CO689_RS02340 dcf6b8965fdc7a91bea2d966c2ee8902 730 PRINTS PR00943 Copper-transporting ATPase signature 192 211 4.1E-20 T 28-03-2018 CO689_RS02340 dcf6b8965fdc7a91bea2d966c2ee8902 730 PRINTS PR00943 Copper-transporting ATPase signature 407 422 4.1E-20 T 28-03-2018 CO689_RS02340 dcf6b8965fdc7a91bea2d966c2ee8902 730 PRINTS PR00943 Copper-transporting ATPase signature 345 359 4.1E-20 T 28-03-2018 CO689_RS02340 dcf6b8965fdc7a91bea2d966c2ee8902 730 PRINTS PR00943 Copper-transporting ATPase signature 47 67 4.1E-20 T 28-03-2018 CO689_RS02340 dcf6b8965fdc7a91bea2d966c2ee8902 730 Pfam PF00702 haloacid dehalogenase-like hydrolase 420 632 9.9E-42 T 28-03-2018 CO689_RS02340 dcf6b8965fdc7a91bea2d966c2ee8902 730 SUPERFAMILY SSF81653 227 322 3.79E-25 T 28-03-2018 IPR008250 P-type ATPase, A domain Reactome: R-HSA-936837 CO689_RS02340 dcf6b8965fdc7a91bea2d966c2ee8902 730 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 139 722 1.4E-179 T 28-03-2018 CO689_RS02340 dcf6b8965fdc7a91bea2d966c2ee8902 730 Gene3D G3DSA:1.20.1110.10 165 439 4.2E-45 T 28-03-2018 CO689_RS02340 dcf6b8965fdc7a91bea2d966c2ee8902 730 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 426 432 - T 28-03-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 CO689_RS02340 dcf6b8965fdc7a91bea2d966c2ee8902 730 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 157 721 2.7E-190 T 28-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 CO689_RS02340 dcf6b8965fdc7a91bea2d966c2ee8902 730 Gene3D G3DSA:3.30.70.100 1 75 7.5E-22 T 28-03-2018 CO689_RS02340 dcf6b8965fdc7a91bea2d966c2ee8902 730 Gene3D G3DSA:3.40.1110.10 440 546 1.7E-24 T 28-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 CO689_RS02340 dcf6b8965fdc7a91bea2d966c2ee8902 730 SUPERFAMILY SSF56784 517 719 3.44E-55 T 28-03-2018 IPR023214 HAD-like domain CO689_RS02340 dcf6b8965fdc7a91bea2d966c2ee8902 730 SUPERFAMILY SSF56784 422 442 3.44E-55 T 28-03-2018 IPR023214 HAD-like domain CO689_RS02340 dcf6b8965fdc7a91bea2d966c2ee8902 730 PRINTS PR00942 Copper-transporting ATPase 1 signature 120 140 2.3E-14 T 28-03-2018 CO689_RS02340 dcf6b8965fdc7a91bea2d966c2ee8902 730 PRINTS PR00942 Copper-transporting ATPase 1 signature 140 165 2.3E-14 T 28-03-2018 CO689_RS02340 dcf6b8965fdc7a91bea2d966c2ee8902 730 PRINTS PR00942 Copper-transporting ATPase 1 signature 26 47 2.3E-14 T 28-03-2018 CO689_RS02340 dcf6b8965fdc7a91bea2d966c2ee8902 730 Pfam PF00122 E1-E2 ATPase 223 402 6.6E-53 T 28-03-2018 CO689_RS02340 dcf6b8965fdc7a91bea2d966c2ee8902 730 SUPERFAMILY SSF55008 1 72 3.27E-20 T 28-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 CO689_RS02340 dcf6b8965fdc7a91bea2d966c2ee8902 730 Gene3D G3DSA:3.40.50.1000 547 684 2.4E-34 T 28-03-2018 IPR023214 HAD-like domain CO689_RS01290 12d3463fc2634ffea53a25835fe8e088 372 Pfam PF00266 Aminotransferase class-V 2 348 2.7E-46 T 28-03-2018 IPR000192 Aminotransferase class V domain CO689_RS01290 12d3463fc2634ffea53a25835fe8e088 372 Gene3D G3DSA:3.90.1150.10 233 368 1.4E-18 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CO689_RS01290 12d3463fc2634ffea53a25835fe8e088 372 Gene3D G3DSA:3.40.640.10 11 232 7.0E-39 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CO689_RS01290 12d3463fc2634ffea53a25835fe8e088 372 PIRSF PIRSF005572 1 365 7.7E-72 T 28-03-2018 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250 CO689_RS01290 12d3463fc2634ffea53a25835fe8e088 372 SUPERFAMILY SSF53383 1 359 9.01E-67 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CO689_RS09435 6d433a0ee537b5e77f7c8b500fc1cd08 241 TIGRFAM TIGR01093 aroD: 3-dehydroquinate dehydratase, type I 21 234 8.9E-52 T 28-03-2018 IPR001381 3-dehydroquinate dehydratase type I GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CO689_RS09435 6d433a0ee537b5e77f7c8b500fc1cd08 241 Gene3D G3DSA:3.20.20.70 1 237 8.6E-60 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CO689_RS09435 6d433a0ee537b5e77f7c8b500fc1cd08 241 Pfam PF01487 Type I 3-dehydroquinase 22 234 6.1E-52 T 28-03-2018 IPR001381 3-dehydroquinate dehydratase type I GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CO689_RS09435 6d433a0ee537b5e77f7c8b500fc1cd08 241 Hamap MF_00214 3-dehydroquinate dehydratase [aroD]. 5 237 31.132 T 28-03-2018 IPR001381 3-dehydroquinate dehydratase type I GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CO689_RS09435 6d433a0ee537b5e77f7c8b500fc1cd08 241 SUPERFAMILY SSF51569 21 237 3.66E-53 T 28-03-2018 CO689_RS09450 465b9756f34a04f6920d109a177a7776 118 Gene3D G3DSA:3.40.30.10 1 116 5.2E-34 T 28-03-2018 CO689_RS09450 465b9756f34a04f6920d109a177a7776 118 TIGRFAM TIGR01617 arsC_related: transcriptional regulator, Spx/MgsR family 2 116 1.0E-40 T 28-03-2018 IPR006504 Transcriptional regulator Spx/MgsR CO689_RS09450 465b9756f34a04f6920d109a177a7776 118 SUPERFAMILY SSF52833 1 115 8.15E-32 T 28-03-2018 IPR012336 Thioredoxin-like fold CO689_RS09450 465b9756f34a04f6920d109a177a7776 118 Pfam PF03960 ArsC family 36 114 2.6E-14 T 28-03-2018 IPR006660 Arsenate reductase-like CO689_RS10445 e46cc133aea76011455af7027ee1897c 324 Gene3D G3DSA:1.10.3470.10 1 321 7.9E-51 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CO689_RS10445 e46cc133aea76011455af7027ee1897c 324 SUPERFAMILY SSF81345 3 314 1.83E-65 T 28-03-2018 IPR029022 ABC transporter, BtuC-like CO689_RS10445 e46cc133aea76011455af7027ee1897c 324 Pfam PF01032 FecCD transport family 15 314 2.5E-72 T 28-03-2018 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 CO689_RS05805 ac771baab83f5b11e2ef0175c84b4a1d 146 SUPERFAMILY SSF46785 16 144 3.35E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS05805 ac771baab83f5b11e2ef0175c84b4a1d 146 Pfam PF13463 Winged helix DNA-binding domain 37 101 3.8E-8 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CO689_RS05805 ac771baab83f5b11e2ef0175c84b4a1d 146 SMART SM00347 29 129 1.5E-10 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CO689_RS05805 ac771baab83f5b11e2ef0175c84b4a1d 146 Gene3D G3DSA:1.10.10.10 1 146 1.1E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS09775 6750b20fce8a3705098368a70ce06e42 237 Pfam PF04630 Phage tail tube protein 63 154 4.3E-7 T 28-03-2018 IPR006724 Phage tail tube protein 1 CO689_RS09775 6750b20fce8a3705098368a70ce06e42 237 TIGRFAM TIGR01603 maj_tail_phi13: phage major tail protein, phi13 family 21 206 5.9E-60 T 28-03-2018 IPR006490 Phage major tail protein, phi13 family CO689_RS03075 60499c9d362ef67f000db5b9bd8747c8 178 Pfam PF00347 Ribosomal protein L6 90 164 2.7E-20 T 28-03-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CO689_RS03075 60499c9d362ef67f000db5b9bd8747c8 178 Pfam PF00347 Ribosomal protein L6 11 82 2.3E-20 T 28-03-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CO689_RS03075 60499c9d362ef67f000db5b9bd8747c8 178 PRINTS PR00059 Ribosomal protein L6 signature 141 162 7.5E-34 T 28-03-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 CO689_RS03075 60499c9d362ef67f000db5b9bd8747c8 178 PRINTS PR00059 Ribosomal protein L6 signature 71 96 7.5E-34 T 28-03-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 CO689_RS03075 60499c9d362ef67f000db5b9bd8747c8 178 PRINTS PR00059 Ribosomal protein L6 signature 99 115 7.5E-34 T 28-03-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 CO689_RS03075 60499c9d362ef67f000db5b9bd8747c8 178 Hamap MF_01365_B 50S ribosomal protein L6 [rplF]. 1 176 38.075 T 28-03-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 CO689_RS03075 60499c9d362ef67f000db5b9bd8747c8 178 TIGRFAM TIGR03654 L6_bact: ribosomal protein uL6 2 176 2.5E-76 T 28-03-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 CO689_RS03075 60499c9d362ef67f000db5b9bd8747c8 178 Gene3D G3DSA:3.90.930.12 83 178 5.3E-40 T 28-03-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CO689_RS03075 60499c9d362ef67f000db5b9bd8747c8 178 ProSitePatterns PS00525 Ribosomal protein L6 signature 1. 154 162 - T 28-03-2018 IPR002358 Ribosomal protein L6, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CO689_RS03075 60499c9d362ef67f000db5b9bd8747c8 178 SUPERFAMILY SSF56053 1 82 3.6E-28 T 28-03-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CO689_RS03075 60499c9d362ef67f000db5b9bd8747c8 178 PIRSF PIRSF002162 1 177 3.2E-51 T 28-03-2018 IPR000702 Ribosomal protein L6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CO689_RS03075 60499c9d362ef67f000db5b9bd8747c8 178 Gene3D G3DSA:3.90.930.12 2 82 6.6E-31 T 28-03-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CO689_RS03075 60499c9d362ef67f000db5b9bd8747c8 178 SUPERFAMILY SSF56053 83 177 6.54E-36 T 28-03-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CO689_RS10420 e727ace4363d96901ee4078f11eb664e 130 TIGRFAM TIGR01168 YSIRK_signal: gram-positive signal peptide, YSIRK family 4 41 2.0E-15 T 28-03-2018 IPR005877 YSIRK Gram-positive signal peptide GO:0016020 CO689_RS10420 e727ace4363d96901ee4078f11eb664e 130 Pfam PF04650 YSIRK type signal peptide 9 31 1.2E-10 T 28-03-2018 IPR005877 YSIRK Gram-positive signal peptide GO:0016020 CO689_RS07710 2f5aaf47f83dc403e2cd6233d6705551 105 Hamap MF_00819 Putative septation protein SpoVG [spoVG]. 1 92 29.2 T 28-03-2018 IPR007170 Stage V sporulation protein G GO:0030435 CO689_RS07710 2f5aaf47f83dc403e2cd6233d6705551 105 Pfam PF04026 SpoVG 1 81 2.6E-36 T 28-03-2018 IPR007170 Stage V sporulation protein G GO:0030435 CO689_RS07710 2f5aaf47f83dc403e2cd6233d6705551 105 Gene3D G3DSA:3.30.1120.40 1 83 1.0E-36 T 28-03-2018 IPR007170 Stage V sporulation protein G GO:0030435 CO689_RS07710 2f5aaf47f83dc403e2cd6233d6705551 105 SUPERFAMILY SSF160537 1 83 5.1E-33 T 28-03-2018 IPR007170 Stage V sporulation protein G GO:0030435 CO689_RS13010 d0a978507e8900d01ed3704b5592e94f 446 Gene3D G3DSA:2.40.50.140 12 101 2.1E-9 T 28-03-2018 CO689_RS13010 d0a978507e8900d01ed3704b5592e94f 446 Pfam PF02601 Exonuclease VII, large subunit 123 435 1.2E-92 T 28-03-2018 IPR020579 Exonuclease VII, large subunit, C-terminal GO:0008855 CO689_RS13010 d0a978507e8900d01ed3704b5592e94f 446 Pfam PF13742 OB-fold nucleic acid binding domain 5 99 2.4E-28 T 28-03-2018 IPR025824 OB-fold nucleic acid binding domain GO:0003676 CO689_RS13010 d0a978507e8900d01ed3704b5592e94f 446 Hamap MF_00378 Exodeoxyribonuclease 7 large subunit [xseA]. 2 438 27.687 T 28-03-2018 IPR003753 Exonuclease VII, large subunit GO:0006308|GO:0008855|GO:0009318 CO689_RS13010 d0a978507e8900d01ed3704b5592e94f 446 TIGRFAM TIGR00237 xseA: exodeoxyribonuclease VII, large subunit 6 350 6.0E-130 T 28-03-2018 IPR003753 Exonuclease VII, large subunit GO:0006308|GO:0008855|GO:0009318 CO689_RS13320 80859393f176dc26ffeff3575f6a9caf 607 SUPERFAMILY SSF54980 301 379 4.68E-18 T 28-03-2018 IPR035647 EF-G domain III/V-like CO689_RS13320 80859393f176dc26ffeff3575f6a9caf 607 SUPERFAMILY SSF52540 9 214 1.02E-55 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CO689_RS13320 80859393f176dc26ffeff3575f6a9caf 607 Gene3D G3DSA:3.30.70.870 297 376 4.9E-27 T 28-03-2018 CO689_RS13320 80859393f176dc26ffeff3575f6a9caf 607 SMART SM00838 407 495 8.2E-6 T 28-03-2018 IPR000640 Elongation factor EFG, domain V-like CO689_RS13320 80859393f176dc26ffeff3575f6a9caf 607 PRINTS PR00315 GTP-binding elongation factor signature 15 28 4.0E-14 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CO689_RS13320 80859393f176dc26ffeff3575f6a9caf 607 PRINTS PR00315 GTP-binding elongation factor signature 83 93 4.0E-14 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CO689_RS13320 80859393f176dc26ffeff3575f6a9caf 607 PRINTS PR00315 GTP-binding elongation factor signature 58 66 4.0E-14 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CO689_RS13320 80859393f176dc26ffeff3575f6a9caf 607 PRINTS PR00315 GTP-binding elongation factor signature 135 144 4.0E-14 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CO689_RS13320 80859393f176dc26ffeff3575f6a9caf 607 PRINTS PR00315 GTP-binding elongation factor signature 99 110 4.0E-14 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CO689_RS13320 80859393f176dc26ffeff3575f6a9caf 607 Gene3D G3DSA:2.40.30.10 197 296 5.6E-27 T 28-03-2018 CO689_RS13320 80859393f176dc26ffeff3575f6a9caf 607 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 51 66 - T 28-03-2018 IPR031157 Tr-type G domain, conserved site CO689_RS13320 80859393f176dc26ffeff3575f6a9caf 607 Pfam PF06421 GTP-binding protein LepA C-terminus 497 603 6.9E-49 T 28-03-2018 IPR013842 GTP-binding protein LepA, C-terminal CO689_RS13320 80859393f176dc26ffeff3575f6a9caf 607 SUPERFAMILY SSF50447 175 296 6.03E-33 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain CO689_RS13320 80859393f176dc26ffeff3575f6a9caf 607 Pfam PF00679 Elongation factor G C-terminus 408 495 1.0E-25 T 28-03-2018 IPR000640 Elongation factor EFG, domain V-like CO689_RS13320 80859393f176dc26ffeff3575f6a9caf 607 Hamap MF_00071 Elongation factor 4 [lepA]. 1 607 304.78 T 28-03-2018 IPR006297 Elongation factor 4 GO:0005525 CO689_RS13320 80859393f176dc26ffeff3575f6a9caf 607 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 14 185 2.0E-19 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 CO689_RS13320 80859393f176dc26ffeff3575f6a9caf 607 SUPERFAMILY SSF54980 408 503 4.75E-28 T 28-03-2018 IPR035647 EF-G domain III/V-like CO689_RS13320 80859393f176dc26ffeff3575f6a9caf 607 Pfam PF00009 Elongation factor Tu GTP binding domain 11 190 3.1E-53 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CO689_RS13320 80859393f176dc26ffeff3575f6a9caf 607 Pfam PF03144 Elongation factor Tu domain 2 214 284 1.8E-12 T 28-03-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 CO689_RS13320 80859393f176dc26ffeff3575f6a9caf 607 Gene3D G3DSA:3.30.70.240 398 559 1.6E-29 T 28-03-2018 CO689_RS13320 80859393f176dc26ffeff3575f6a9caf 607 Gene3D G3DSA:3.40.50.300 8 194 2.0E-37 T 28-03-2018 CO689_RS13320 80859393f176dc26ffeff3575f6a9caf 607 TIGRFAM TIGR01393 lepA: elongation factor 4 12 605 0.0 T 28-03-2018 IPR006297 Elongation factor 4 GO:0005525 CO689_RS09175 e998e1505c91681b51cee7d2e5dfb947 314 Pfam PF10298 WhiA N-terminal LAGLIDADG-like domain 19 103 2.9E-33 T 28-03-2018 IPR018478 Sporulation transcription regulator WhiA, N-terminal domain CO689_RS09175 e998e1505c91681b51cee7d2e5dfb947 314 Pfam PF02650 WhiA C-terminal HTH domain 219 303 9.3E-36 T 28-03-2018 IPR023054 Sporulation regulator WhiA, C-terminal CO689_RS09175 e998e1505c91681b51cee7d2e5dfb947 314 Gene3D G3DSA:3.10.28.10 14 100 3.8E-10 T 28-03-2018 IPR027434 Homing endonuclease GO:0004519 CO689_RS09175 e998e1505c91681b51cee7d2e5dfb947 314 Hamap MF_01420 Putative sporulation transcription regulator WhiA [whiA]. 3 306 34.634 T 28-03-2018 IPR003802 Sporulation regulator WhiA GO:0043937 CO689_RS09175 e998e1505c91681b51cee7d2e5dfb947 314 TIGRFAM TIGR00647 DNA_bind_WhiA: DNA-binding protein WhiA 4 304 1.1E-129 T 28-03-2018 IPR033981 Sporulation regulator WhiA-like CO689_RS09175 e998e1505c91681b51cee7d2e5dfb947 314 Gene3D G3DSA:3.10.28.10 122 202 5.9E-14 T 28-03-2018 IPR027434 Homing endonuclease GO:0004519 CO689_RS09175 e998e1505c91681b51cee7d2e5dfb947 314 SUPERFAMILY SSF55608 119 220 3.29E-18 T 28-03-2018 IPR027434 Homing endonuclease GO:0004519 CO689_RS09175 e998e1505c91681b51cee7d2e5dfb947 314 Pfam PF14527 WhiA LAGLIDADG-like domain 124 216 1.1E-34 T 28-03-2018 CO689_RS09175 e998e1505c91681b51cee7d2e5dfb947 314 Gene3D G3DSA:1.10.10.10 238 303 0.0021 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS09050 15bbf87735916cd395cc8944cbbec052 409 PIRSF PIRSF037215 1 408 6.8E-184 T 28-03-2018 IPR010161 Peptidase M20B, tripeptide aminopeptidase GO:0005737|GO:0006518|GO:0008270|GO:0045148 CO689_RS09050 15bbf87735916cd395cc8944cbbec052 409 SUPERFAMILY SSF53187 322 403 2.33E-80 T 28-03-2018 CO689_RS09050 15bbf87735916cd395cc8944cbbec052 409 SUPERFAMILY SSF53187 3 210 2.33E-80 T 28-03-2018 CO689_RS09050 15bbf87735916cd395cc8944cbbec052 409 Pfam PF07687 Peptidase dimerisation domain 208 308 1.5E-11 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain CO689_RS09050 15bbf87735916cd395cc8944cbbec052 409 Gene3D G3DSA:3.40.630.10 1 409 4.0E-52 T 28-03-2018 CO689_RS09050 15bbf87735916cd395cc8944cbbec052 409 ProSitePatterns PS00759 ArgE / dapE / ACY1 / CPG2 / yscS family signature 2. 138 177 - T 28-03-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 CO689_RS09050 15bbf87735916cd395cc8944cbbec052 409 ProSitePatterns PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. 73 82 - T 28-03-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 CO689_RS09050 15bbf87735916cd395cc8944cbbec052 409 SUPERFAMILY SSF55031 209 319 3.4E-40 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain CO689_RS09050 15bbf87735916cd395cc8944cbbec052 409 Hamap MF_00550 Peptidase T [pepT]. 2 404 54.699 T 28-03-2018 IPR010161 Peptidase M20B, tripeptide aminopeptidase GO:0005737|GO:0006518|GO:0008270|GO:0045148 CO689_RS09050 15bbf87735916cd395cc8944cbbec052 409 TIGRFAM TIGR01882 peptidase-T: peptidase T 3 403 1.7E-170 T 28-03-2018 IPR010161 Peptidase M20B, tripeptide aminopeptidase GO:0005737|GO:0006518|GO:0008270|GO:0045148 CO689_RS09050 15bbf87735916cd395cc8944cbbec052 409 Pfam PF01546 Peptidase family M20/M25/M40 139 402 8.5E-15 T 28-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CO689_RS12430 4844a1778c94006bf8ae71be781ce152 314 Gene3D G3DSA:3.40.190.10 170 314 2.0E-18 T 28-03-2018 CO689_RS12430 4844a1778c94006bf8ae71be781ce152 314 TIGRFAM TIGR02136 ptsS_2: phosphate binding protein 1 296 3.2E-91 T 28-03-2018 IPR011862 Phosphate binding protein GO:0006810 CO689_RS12430 4844a1778c94006bf8ae71be781ce152 314 SUPERFAMILY SSF53850 41 310 7.74E-70 T 28-03-2018 CO689_RS12430 4844a1778c94006bf8ae71be781ce152 314 Gene3D G3DSA:3.40.190.10 41 169 1.5E-36 T 28-03-2018 CO689_RS12430 4844a1778c94006bf8ae71be781ce152 314 Pfam PF12849 PBP superfamily domain 37 284 8.3E-44 T 28-03-2018 IPR024370 PBP domain CO689_RS02425 0d912d0591fd795356a15907525d2423 62 Pfam PF11772 DNA-directed RNA polymerase subunit beta 18 60 3.9E-8 T 28-03-2018 IPR024596 DNA-directed RNA polymerase subunit beta/EpuA CO689_RS12760 4915522a88bf9b48d7e69c6ec74f19db 415 Gene3D G3DSA:1.25.40.10 12 184 5.4E-21 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CO689_RS12760 4915522a88bf9b48d7e69c6ec74f19db 415 Gene3D G3DSA:1.25.40.10 185 233 1.5E-8 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CO689_RS12760 4915522a88bf9b48d7e69c6ec74f19db 415 SUPERFAMILY SSF48452 26 92 6.45E-5 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CO689_RS12760 4915522a88bf9b48d7e69c6ec74f19db 415 Gene3D G3DSA:1.25.40.10 303 415 4.3E-11 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CO689_RS12760 4915522a88bf9b48d7e69c6ec74f19db 415 SMART SM00028 200 233 24.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CO689_RS12760 4915522a88bf9b48d7e69c6ec74f19db 415 SMART SM00028 167 197 150.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CO689_RS12760 4915522a88bf9b48d7e69c6ec74f19db 415 SMART SM00028 96 129 41.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CO689_RS12760 4915522a88bf9b48d7e69c6ec74f19db 415 SMART SM00028 234 267 78.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CO689_RS12760 4915522a88bf9b48d7e69c6ec74f19db 415 SUPERFAMILY SSF48452 97 413 3.03E-23 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CO689_RS12760 4915522a88bf9b48d7e69c6ec74f19db 415 Pfam PF14559 Tetratricopeptide repeat 347 407 8.1E-8 T 28-03-2018 CO689_RS12760 4915522a88bf9b48d7e69c6ec74f19db 415 Gene3D G3DSA:1.25.40.10 234 301 1.7E-9 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CO689_RS05515 14d936e0694fbf0e02ae7aaf5fd7c827 374 Gene3D G3DSA:1.10.720.10 141 183 3.1E-6 T 28-03-2018 CO689_RS06515 cab571ea9b0a0fa3d30121dec737ecbd 412 Pfam PF09211 Domain of unknown function (DUF1958) 315 378 7.3E-23 T 28-03-2018 IPR015294 Penicillin-binding protein 4, C-terminal domain CO689_RS06515 cab571ea9b0a0fa3d30121dec737ecbd 412 SUPERFAMILY SSF69189 314 376 1.1E-20 T 28-03-2018 IPR015956 Penicillin-binding protein-associated GO:0004180|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 CO689_RS06515 cab571ea9b0a0fa3d30121dec737ecbd 412 Gene3D G3DSA:3.40.710.10 28 312 2.1E-39 T 28-03-2018 CO689_RS06515 cab571ea9b0a0fa3d30121dec737ecbd 412 Gene3D G3DSA:2.30.140.20 313 377 2.2E-25 T 28-03-2018 IPR015294 Penicillin-binding protein 4, C-terminal domain CO689_RS06515 cab571ea9b0a0fa3d30121dec737ecbd 412 SUPERFAMILY SSF56601 5 313 1.03E-58 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CO689_RS06515 cab571ea9b0a0fa3d30121dec737ecbd 412 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 47 286 2.5E-50 T 28-03-2018 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 CO689_RS06515 cab571ea9b0a0fa3d30121dec737ecbd 412 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 155 168 3.0E-13 T 28-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 CO689_RS06515 cab571ea9b0a0fa3d30121dec737ecbd 412 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 71 82 3.0E-13 T 28-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 CO689_RS06515 cab571ea9b0a0fa3d30121dec737ecbd 412 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 128 145 3.0E-13 T 28-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 CO689_RS11615 8d53bd77ae869baecc5adaa8b1eb116c 162 SUPERFAMILY SSF55136 1 157 8.89E-18 T 28-03-2018 CO689_RS11615 8d53bd77ae869baecc5adaa8b1eb116c 162 Gene3D G3DSA:3.20.80.10 1 156 8.7E-31 T 28-03-2018 IPR011256 Regulatory factor, effector binding domain CO689_RS11615 8d53bd77ae869baecc5adaa8b1eb116c 162 SMART SM00871 1 155 1.4E-19 T 28-03-2018 IPR010499 Bacterial transcription activator, effector binding CO689_RS11615 8d53bd77ae869baecc5adaa8b1eb116c 162 Pfam PF06445 GyrI-like small molecule binding domain 1 154 1.8E-15 T 28-03-2018 IPR029442 GyrI-like small molecule binding domain CO689_RS12070 7e30367b249df90348214ebddc1059a3 124 SUPERFAMILY SSF46785 12 121 3.13E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS12070 7e30367b249df90348214ebddc1059a3 124 Gene3D G3DSA:1.10.10.10 2 124 1.8E-4 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS10120 a012888e061820c5c0cf4637f1e17736 440 Gene3D G3DSA:3.50.50.60 143 315 2.2E-23 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CO689_RS10120 a012888e061820c5c0cf4637f1e17736 440 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 150 175 1.7E-12 T 28-03-2018 CO689_RS10120 a012888e061820c5c0cf4637f1e17736 440 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 272 279 1.7E-12 T 28-03-2018 CO689_RS10120 a012888e061820c5c0cf4637f1e17736 440 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 231 245 1.7E-12 T 28-03-2018 CO689_RS10120 a012888e061820c5c0cf4637f1e17736 440 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 3 25 1.7E-12 T 28-03-2018 CO689_RS10120 a012888e061820c5c0cf4637f1e17736 440 Gene3D G3DSA:3.30.390.30 322 440 7.2E-20 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CO689_RS10120 a012888e061820c5c0cf4637f1e17736 440 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 325 424 4.1E-9 T 28-03-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 CO689_RS10120 a012888e061820c5c0cf4637f1e17736 440 Gene3D G3DSA:3.50.50.60 2 134 1.2E-15 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CO689_RS10120 a012888e061820c5c0cf4637f1e17736 440 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 150 168 1.6E-19 T 28-03-2018 CO689_RS10120 a012888e061820c5c0cf4637f1e17736 440 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 257 279 1.6E-19 T 28-03-2018 CO689_RS10120 a012888e061820c5c0cf4637f1e17736 440 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 230 246 1.6E-19 T 28-03-2018 CO689_RS10120 a012888e061820c5c0cf4637f1e17736 440 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 106 124 1.6E-19 T 28-03-2018 CO689_RS10120 a012888e061820c5c0cf4637f1e17736 440 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 4 23 1.6E-19 T 28-03-2018 CO689_RS10120 a012888e061820c5c0cf4637f1e17736 440 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 3 290 9.8E-50 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CO689_RS10120 a012888e061820c5c0cf4637f1e17736 440 SUPERFAMILY SSF55424 319 439 1.32E-26 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CO689_RS10120 a012888e061820c5c0cf4637f1e17736 440 SUPERFAMILY SSF51905 1 309 1.37E-33 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CO689_RS03730 9f231ba13cb8fba633fbd3665ebf835f 345 Hamap MF_00354 Isopentenyl-diphosphate delta-isomerase [fni]. 6 333 37.198 T 28-03-2018 IPR011179 Isopentenyl-diphosphate delta-isomerase, FMN-dependent GO:0004452|GO:0005737|GO:0008299|GO:0010181 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922 CO689_RS03730 9f231ba13cb8fba633fbd3665ebf835f 345 TIGRFAM TIGR02151 IPP_isom_2: isopentenyl-diphosphate delta-isomerase, type 2 8 331 3.0E-123 T 28-03-2018 IPR011179 Isopentenyl-diphosphate delta-isomerase, FMN-dependent GO:0004452|GO:0005737|GO:0008299|GO:0010181 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922 CO689_RS03730 9f231ba13cb8fba633fbd3665ebf835f 345 SUPERFAMILY SSF51395 25 343 1.97E-82 T 28-03-2018 CO689_RS03730 9f231ba13cb8fba633fbd3665ebf835f 345 Gene3D G3DSA:3.20.20.70 6 345 1.2E-71 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CO689_RS03730 9f231ba13cb8fba633fbd3665ebf835f 345 PIRSF PIRSF003314 3 343 2.5E-128 T 28-03-2018 IPR011179 Isopentenyl-diphosphate delta-isomerase, FMN-dependent GO:0004452|GO:0005737|GO:0008299|GO:0010181 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922 CO689_RS03730 9f231ba13cb8fba633fbd3665ebf835f 345 Pfam PF01070 FMN-dependent dehydrogenase 164 329 9.0E-20 T 28-03-2018 IPR000262 FMN-dependent dehydrogenase GO:0016491 CO689_RS11055 79e40e28187ffd449972f9bdc6dc692f 801 SUPERFAMILY SSF50249 39 200 6.61E-46 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CO689_RS11055 79e40e28187ffd449972f9bdc6dc692f 801 SMART SM00873 220 393 1.1E-86 T 28-03-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 CO689_RS11055 79e40e28187ffd449972f9bdc6dc692f 801 Gene3D G3DSA:3.50.40.10 203 404 3.4E-72 T 28-03-2018 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 CO689_RS11055 79e40e28187ffd449972f9bdc6dc692f 801 TIGRFAM TIGR00472 pheT_bact: phenylalanine--tRNA ligase, beta subunit 1 801 1.2E-262 T 28-03-2018 IPR004532 Phenylalanine-tRNA ligase, class IIc, beta subunit GO:0000287|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 CO689_RS11055 79e40e28187ffd449972f9bdc6dc692f 801 SMART SM00896 709 801 6.2E-42 T 28-03-2018 IPR005121 Ferrodoxin-fold anticodon-binding domain KEGG: 00970+6.1.1.20 CO689_RS11055 79e40e28187ffd449972f9bdc6dc692f 801 Gene3D G3DSA:3.30.56.10 408 482 1.4E-23 T 28-03-2018 CO689_RS11055 79e40e28187ffd449972f9bdc6dc692f 801 SUPERFAMILY SSF56037 208 401 2.2E-71 T 28-03-2018 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 CO689_RS11055 79e40e28187ffd449972f9bdc6dc692f 801 Gene3D G3DSA:3.30.930.10 497 696 7.3E-35 T 28-03-2018 CO689_RS11055 79e40e28187ffd449972f9bdc6dc692f 801 SUPERFAMILY SSF46955 412 482 2.84E-19 T 28-03-2018 IPR009061 Putative DNA-binding domain CO689_RS11055 79e40e28187ffd449972f9bdc6dc692f 801 Gene3D G3DSA:2.40.50.140 54 160 3.0E-41 T 28-03-2018 CO689_RS11055 79e40e28187ffd449972f9bdc6dc692f 801 Hamap MF_00283 Phenylalanine--tRNA ligase beta subunit [pheT]. 1 796 45.832 T 28-03-2018 IPR004532 Phenylalanine-tRNA ligase, class IIc, beta subunit GO:0000287|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 CO689_RS11055 79e40e28187ffd449972f9bdc6dc692f 801 Pfam PF01588 Putative tRNA binding domain 45 151 6.3E-24 T 28-03-2018 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 CO689_RS11055 79e40e28187ffd449972f9bdc6dc692f 801 Pfam PF03483 B3/4 domain 221 392 4.7E-66 T 28-03-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 CO689_RS11055 79e40e28187ffd449972f9bdc6dc692f 801 SUPERFAMILY SSF54991 704 799 1.96E-28 T 28-03-2018 IPR005121 Ferrodoxin-fold anticodon-binding domain KEGG: 00970+6.1.1.20 CO689_RS11055 79e40e28187ffd449972f9bdc6dc692f 801 Gene3D G3DSA:3.30.70.380 705 801 1.5E-24 T 28-03-2018 IPR005121 Ferrodoxin-fold anticodon-binding domain KEGG: 00970+6.1.1.20 CO689_RS11055 79e40e28187ffd449972f9bdc6dc692f 801 SMART SM00874 410 478 1.7E-24 T 28-03-2018 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 CO689_RS11055 79e40e28187ffd449972f9bdc6dc692f 801 Gene3D G3DSA:3.30.56.10 1 53 3.0E-7 T 28-03-2018 CO689_RS11055 79e40e28187ffd449972f9bdc6dc692f 801 Pfam PF03484 tRNA synthetase B5 domain 413 478 7.5E-20 T 28-03-2018 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 CO689_RS11055 79e40e28187ffd449972f9bdc6dc692f 801 SUPERFAMILY SSF55681 474 697 2.39E-48 T 28-03-2018 CO689_RS11055 79e40e28187ffd449972f9bdc6dc692f 801 Pfam PF03147 Ferredoxin-fold anticodon binding domain 709 799 2.3E-27 T 28-03-2018 IPR005121 Ferrodoxin-fold anticodon-binding domain KEGG: 00970+6.1.1.20 CO689_RS10485 5053e80456a36690d1be4587981a597a 328 Pfam PF03099 Biotin/lipoate A/B protein ligase family 52 154 5.4E-7 T 28-03-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 CO689_RS10485 5053e80456a36690d1be4587981a597a 328 TIGRFAM TIGR00545 lipoyltrans: lipoyltransferase and lipoate-protein ligase 2 321 2.9E-116 T 28-03-2018 IPR004562 Lipoyltransferase/lipoate-protein ligase GO:0009249 KEGG: 00785+6.3.1.20|Reactome: R-HSA-389661 CO689_RS10485 5053e80456a36690d1be4587981a597a 328 SUPERFAMILY SSF55681 4 241 9.23E-80 T 28-03-2018 CO689_RS10485 5053e80456a36690d1be4587981a597a 328 Gene3D G3DSA:3.30.390.50 247 328 1.2E-23 T 28-03-2018 CO689_RS10485 5053e80456a36690d1be4587981a597a 328 Pfam PF10437 Bacterial lipoate protein ligase C-terminus 243 326 9.4E-26 T 28-03-2018 IPR019491 Lipoate protein ligase, C-terminal KEGG: 00785+6.3.1.20 CO689_RS10485 5053e80456a36690d1be4587981a597a 328 Gene3D G3DSA:3.30.930.10 2 246 1.0E-69 T 28-03-2018 CO689_RS10485 5053e80456a36690d1be4587981a597a 328 SUPERFAMILY SSF82649 242 327 3.82E-24 T 28-03-2018 CO689_RS12915 54a448ab1335f1a34b7fdb1545225185 269 PIRSF PIRSF000193 1 268 9.3E-87 T 28-03-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 CO689_RS12915 54a448ab1335f1a34b7fdb1545225185 269 Hamap MF_01925 Pyrroline-5-carboxylate reductase [proC]. 1 265 21.752 T 28-03-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 CO689_RS12915 54a448ab1335f1a34b7fdb1545225185 269 TIGRFAM TIGR00112 proC: pyrroline-5-carboxylate reductase 3 265 1.8E-80 T 28-03-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 CO689_RS12915 54a448ab1335f1a34b7fdb1545225185 269 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 2 98 2.2E-14 T 28-03-2018 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal CO689_RS12915 54a448ab1335f1a34b7fdb1545225185 269 SUPERFAMILY SSF48179 160 267 5.44E-29 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CO689_RS12915 54a448ab1335f1a34b7fdb1545225185 269 SUPERFAMILY SSF51735 1 159 1.69E-28 T 28-03-2018 IPR016040 NAD(P)-binding domain CO689_RS12915 54a448ab1335f1a34b7fdb1545225185 269 Gene3D G3DSA:1.10.3730.10 164 269 1.1E-30 T 28-03-2018 CO689_RS12915 54a448ab1335f1a34b7fdb1545225185 269 Gene3D G3DSA:3.40.50.720 1 163 1.2E-22 T 28-03-2018 CO689_RS12915 54a448ab1335f1a34b7fdb1545225185 269 Pfam PF14748 Pyrroline-5-carboxylate reductase dimerisation 161 265 2.1E-29 T 28-03-2018 IPR029036 Pyrroline-5-carboxylate reductase, dimerisation domain KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 CO689_RS13065 987f0f45c3fffd96d2dc724c85707f40 491 Pfam PF00266 Aminotransferase class-V 161 281 1.7E-9 T 28-03-2018 IPR000192 Aminotransferase class V domain CO689_RS13065 987f0f45c3fffd96d2dc724c85707f40 491 SUPERFAMILY SSF53383 9 483 3.56E-112 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CO689_RS13065 987f0f45c3fffd96d2dc724c85707f40 491 Gene3D G3DSA:3.90.1150.10 345 470 4.2E-44 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CO689_RS13065 987f0f45c3fffd96d2dc724c85707f40 491 Hamap MF_00713 Probable glycine dehydrogenase (decarboxylating) subunit 2 [gcvPB]. 7 485 58.697 T 28-03-2018 IPR023012 Probable glycine dehydrogenase (decarboxylating) subunit 2 GO:0004375|GO:0019464 KEGG: 00260+1.4.4.2 CO689_RS13065 987f0f45c3fffd96d2dc724c85707f40 491 Gene3D G3DSA:3.40.640.10 83 344 8.9E-40 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CO689_RS12880 d68aff270f8c644e22662fcbb4f28f96 243 Hamap MF_01805 Segregation and condensation protein A [scpA]. 2 239 24.139 T 28-03-2018 IPR003768 Segregation and condensation protein A CO689_RS12880 d68aff270f8c644e22662fcbb4f28f96 243 Gene3D G3DSA:1.10.10.580 166 237 5.7E-12 T 28-03-2018 CO689_RS12880 d68aff270f8c644e22662fcbb4f28f96 243 Pfam PF02616 Segregation and condensation protein ScpA 19 236 3.6E-37 T 28-03-2018 IPR003768 Segregation and condensation protein A CO689_RS10900 c2dc4f1b27b75f2570a1a1852644bb53 270 SUPERFAMILY SSF161098 8 247 1.7E-44 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CO689_RS10900 c2dc4f1b27b75f2570a1a1852644bb53 270 Gene3D G3DSA:1.10.3720.10 3 266 3.1E-36 T 28-03-2018 CO689_RS10900 c2dc4f1b27b75f2570a1a1852644bb53 270 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 78 262 3.8E-16 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CO689_RS00350 3653b7574ddc8dbbf990511ed0d189ea 428 SUPERFAMILY SSF56672 17 353 8.01E-54 T 28-03-2018 CO689_RS00350 3653b7574ddc8dbbf990511ed0d189ea 428 Pfam PF00078 Reverse transcriptase (RNA-dependent DNA polymerase) 72 277 3.9E-44 T 28-03-2018 IPR000477 Reverse transcriptase domain CO689_RS00350 3653b7574ddc8dbbf990511ed0d189ea 428 TIGRFAM TIGR04416 group_II_RT_mat: group II intron reverse transcriptase/maturase 16 361 3.3E-118 T 28-03-2018 IPR030931 Group II intron reverse transcriptase/maturase CO689_RS00350 3653b7574ddc8dbbf990511ed0d189ea 428 Pfam PF08388 Group II intron, maturase-specific domain 297 375 1.2E-14 T 28-03-2018 IPR013597 Group II intron, maturase-specific CO689_RS00350 3653b7574ddc8dbbf990511ed0d189ea 428 Gene3D G3DSA:3.30.70.270 90 280 4.0E-35 T 28-03-2018 CO689_RS02725 44b6984d449140d27c3722df9c350c16 451 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 3 136 1.2E-42 T 28-03-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CO689_RS02725 44b6984d449140d27c3722df9c350c16 451 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 375 443 2.0E-17 T 28-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CO689_RS02725 44b6984d449140d27c3722df9c350c16 451 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 96 105 - T 28-03-2018 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CO689_RS02725 44b6984d449140d27c3722df9c350c16 451 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 95 109 3.6E-12 T 28-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CO689_RS02725 44b6984d449140d27c3722df9c350c16 451 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 175 194 3.6E-12 T 28-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CO689_RS02725 44b6984d449140d27c3722df9c350c16 451 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 235 250 3.6E-12 T 28-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CO689_RS02725 44b6984d449140d27c3722df9c350c16 451 Hamap MF_01554_B Phosphoglucosamine mutase [glmM]. 1 446 44.58 T 28-03-2018 IPR006352 Phosphoglucosamine mutase, bacterial type GO:0000287|GO:0005975|GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CO689_RS02725 44b6984d449140d27c3722df9c350c16 451 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 160 255 6.4E-15 T 28-03-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CO689_RS02725 44b6984d449140d27c3722df9c350c16 451 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 259 371 5.6E-33 T 28-03-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CO689_RS02725 44b6984d449140d27c3722df9c350c16 451 Gene3D G3DSA:3.30.310.50 376 448 1.9E-24 T 28-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CO689_RS02725 44b6984d449140d27c3722df9c350c16 451 SUPERFAMILY SSF53738 159 258 2.08E-25 T 28-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CO689_RS02725 44b6984d449140d27c3722df9c350c16 451 SUPERFAMILY SSF53738 3 181 1.65E-46 T 28-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CO689_RS02725 44b6984d449140d27c3722df9c350c16 451 Gene3D G3DSA:3.40.120.10 265 375 7.2E-33 T 28-03-2018 CO689_RS02725 44b6984d449140d27c3722df9c350c16 451 SUPERFAMILY SSF53738 259 367 2.71E-30 T 28-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CO689_RS02725 44b6984d449140d27c3722df9c350c16 451 TIGRFAM TIGR01455 glmM: phosphoglucosamine mutase 5 445 7.0E-182 T 28-03-2018 IPR006352 Phosphoglucosamine mutase, bacterial type GO:0000287|GO:0005975|GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CO689_RS02725 44b6984d449140d27c3722df9c350c16 451 SUPERFAMILY SSF55957 359 448 7.85E-26 T 28-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CO689_RS02725 44b6984d449140d27c3722df9c350c16 451 Gene3D G3DSA:3.40.120.10 168 264 6.3E-24 T 28-03-2018 CO689_RS02725 44b6984d449140d27c3722df9c350c16 451 Gene3D G3DSA:3.40.120.10 2 167 6.7E-43 T 28-03-2018 CO689_RS11470 aa555f95a71352d87414b0056c82b0a2 291 Gene3D G3DSA:3.40.50.300 62 223 1.1E-16 T 28-03-2018 CO689_RS11470 aa555f95a71352d87414b0056c82b0a2 291 Hamap MF_01820 Putative ribosome biogenesis GTPase RsgA [rsgA]. 2 288 36.17 T 28-03-2018 IPR004881 Ribosome biogenesis GTPase RsgA GO:0003924|GO:0005525 CO689_RS11470 aa555f95a71352d87414b0056c82b0a2 291 SUPERFAMILY SSF52540 65 288 1.07E-51 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CO689_RS11470 aa555f95a71352d87414b0056c82b0a2 291 TIGRFAM TIGR00157 TIGR00157: ribosome small subunit-dependent GTPase A 39 282 1.1E-75 T 28-03-2018 IPR004881 Ribosome biogenesis GTPase RsgA GO:0003924|GO:0005525 CO689_RS11470 aa555f95a71352d87414b0056c82b0a2 291 SUPERFAMILY SSF50249 3 63 1.29E-12 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CO689_RS11470 aa555f95a71352d87414b0056c82b0a2 291 Gene3D G3DSA:2.40.50.140 1 61 1.8E-17 T 28-03-2018 CO689_RS11470 aa555f95a71352d87414b0056c82b0a2 291 Gene3D G3DSA:1.10.40.50 224 291 1.1E-22 T 28-03-2018 CO689_RS11470 aa555f95a71352d87414b0056c82b0a2 291 Pfam PF03193 RsgA GTPase 59 223 4.3E-55 T 28-03-2018 IPR010914 RsgA GTPase domain GO:0003924|GO:0005525 CO689_RS11470 aa555f95a71352d87414b0056c82b0a2 291 Pfam PF16745 RsgA N-terminal domain 3 56 4.4E-20 T 28-03-2018 IPR031944 Ribosome biogenesis GTPase RsgA, N-terminal CO689_RS04525 ce44483b7249ced1aa071529ffc752a8 433 SUPERFAMILY SSF52418 69 329 1.01E-93 T 28-03-2018 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CO689_RS04525 ce44483b7249ced1aa071529ffc752a8 433 SMART SM00941 345 418 2.6E-33 T 28-03-2018 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CO689_RS04525 ce44483b7249ced1aa071529ffc752a8 433 SUPERFAMILY SSF47648 1 69 2.49E-23 T 28-03-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 CO689_RS04525 ce44483b7249ced1aa071529ffc752a8 433 PIRSF PIRSF000478 1 433 8.0E-168 T 28-03-2018 IPR000053 Thymidine/pyrimidine-nucleoside phosphorylase GO:0004645|GO:0006206 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CO689_RS04525 ce44483b7249ced1aa071529ffc752a8 433 Gene3D G3DSA:3.40.1030.10 68 337 1.4E-95 T 28-03-2018 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CO689_RS04525 ce44483b7249ced1aa071529ffc752a8 433 Gene3D G3DSA:1.20.970.10 1 66 1.3E-25 T 28-03-2018 CO689_RS04525 ce44483b7249ced1aa071529ffc752a8 433 Pfam PF02885 Glycosyl transferase family, helical bundle domain 4 66 3.2E-21 T 28-03-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 CO689_RS04525 ce44483b7249ced1aa071529ffc752a8 433 Pfam PF00591 Glycosyl transferase family, a/b domain 78 306 6.8E-50 T 28-03-2018 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CO689_RS04525 ce44483b7249ced1aa071529ffc752a8 433 ProSitePatterns PS00647 Thymidine and pyrimidine-nucleoside phosphorylases signature. 110 125 - T 28-03-2018 IPR017872 Pyrimidine-nucleoside phosphorylase, conserved site GO:0006206 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CO689_RS04525 ce44483b7249ced1aa071529ffc752a8 433 Gene3D G3DSA:3.90.1170.30 338 423 2.5E-28 T 28-03-2018 CO689_RS04525 ce44483b7249ced1aa071529ffc752a8 433 Pfam PF07831 Pyrimidine nucleoside phosphorylase C-terminal domain 345 418 9.4E-27 T 28-03-2018 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CO689_RS04525 ce44483b7249ced1aa071529ffc752a8 433 TIGRFAM TIGR02644 Y_phosphoryl: pyrimidine-nucleoside phosphorylase 3 417 1.1E-181 T 28-03-2018 IPR018090 Pyrimidine-nucleoside phosphorylase, bacterial/eukaryotic GO:0006213|GO:0016154 KEGG: 00240+2.4.2.4|KEGG: 00983+2.4.2.4|MetaCyc: PWY-7181|Reactome: R-HSA-73614|Reactome: R-HSA-73621 CO689_RS04525 ce44483b7249ced1aa071529ffc752a8 433 SUPERFAMILY SSF54680 331 431 6.93E-28 T 28-03-2018 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CO689_RS09635 5a1526737a3e62f3b3c5055eea92b70a 261 Pfam PF01695 IstB-like ATP binding protein 86 226 3.4E-18 T 28-03-2018 IPR002611 IstB-like ATP-binding protein GO:0005524 CO689_RS09635 5a1526737a3e62f3b3c5055eea92b70a 261 Gene3D G3DSA:3.40.50.300 62 253 3.8E-17 T 28-03-2018 CO689_RS09635 5a1526737a3e62f3b3c5055eea92b70a 261 SUPERFAMILY SSF52540 85 244 3.42E-20 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CO689_RS13140 95bf790bc3a037438594da5bf9794b41 180 TIGRFAM TIGR02727 MTHFS_bact: 5-formyltetrahydrofolate cyclo-ligase 3 175 2.8E-44 T 28-03-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase CO689_RS13140 95bf790bc3a037438594da5bf9794b41 180 Pfam PF01812 5-formyltetrahydrofolate cyclo-ligase family 3 175 5.6E-33 T 28-03-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase CO689_RS13140 95bf790bc3a037438594da5bf9794b41 180 Gene3D G3DSA:3.40.50.10420 1 179 4.0E-42 T 28-03-2018 CO689_RS13140 95bf790bc3a037438594da5bf9794b41 180 SUPERFAMILY SSF100950 1 176 6.28E-40 T 28-03-2018 CO689_RS13140 95bf790bc3a037438594da5bf9794b41 180 PIRSF PIRSF006806 1 180 1.7E-41 T 28-03-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase CO689_RS03805 4870a92eee1a9e07fd8f90abd48c5a35 224 Gene3D G3DSA:1.10.10.10 120 224 4.4E-27 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS03805 4870a92eee1a9e07fd8f90abd48c5a35 224 Gene3D G3DSA:3.40.50.2300 1 119 7.9E-34 T 28-03-2018 CO689_RS03805 4870a92eee1a9e07fd8f90abd48c5a35 224 Pfam PF00072 Response regulator receiver domain 5 112 3.1E-28 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CO689_RS03805 4870a92eee1a9e07fd8f90abd48c5a35 224 SMART SM00862 145 220 7.6E-22 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CO689_RS03805 4870a92eee1a9e07fd8f90abd48c5a35 224 SUPERFAMILY SSF52172 2 174 6.94E-40 T 28-03-2018 IPR011006 CheY-like superfamily CO689_RS03805 4870a92eee1a9e07fd8f90abd48c5a35 224 Pfam PF00486 Transcriptional regulatory protein, C terminal 147 219 2.5E-24 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CO689_RS03805 4870a92eee1a9e07fd8f90abd48c5a35 224 SMART SM00448 2 112 1.6E-34 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CO689_RS03080 ea633acb37700a36a0b9f3f0f80ec01b 132 Gene3D G3DSA:3.30.1370.30 1 67 3.1E-26 T 28-03-2018 CO689_RS03080 ea633acb37700a36a0b9f3f0f80ec01b 132 SUPERFAMILY SSF56047 3 132 1.7E-48 T 28-03-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CO689_RS03080 ea633acb37700a36a0b9f3f0f80ec01b 132 Hamap MF_01302_B 30S ribosomal protein S8 [rpsH]. 2 132 33.269 T 28-03-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CO689_RS03080 ea633acb37700a36a0b9f3f0f80ec01b 132 Gene3D G3DSA:3.30.1490.10 76 131 8.0E-24 T 28-03-2018 CO689_RS03080 ea633acb37700a36a0b9f3f0f80ec01b 132 ProSitePatterns PS00053 Ribosomal protein S8 signature. 102 119 - T 28-03-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CO689_RS03080 ea633acb37700a36a0b9f3f0f80ec01b 132 Pfam PF00410 Ribosomal protein S8 5 132 8.5E-54 T 28-03-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CO689_RS07205 6c90a65ecab255620e97dd92c87b9eca 258 SUPERFAMILY SSF56529 6 257 5.19E-51 T 28-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CO689_RS07205 6c90a65ecab255620e97dd92c87b9eca 258 Gene3D G3DSA:3.90.850.10 2 258 1.1E-27 T 28-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CO689_RS06055 b86a9f50dd23f81609be8ac40ca17034 340 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 6 16 1.7E-5 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CO689_RS06055 b86a9f50dd23f81609be8ac40ca17034 340 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 16 26 1.7E-5 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CO689_RS06055 b86a9f50dd23f81609be8ac40ca17034 340 Gene3D G3DSA:1.10.260.40 6 57 3.4E-22 T 28-03-2018 CO689_RS06055 b86a9f50dd23f81609be8ac40ca17034 340 Pfam PF00356 Bacterial regulatory proteins, lacI family 6 52 2.0E-20 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CO689_RS06055 b86a9f50dd23f81609be8ac40ca17034 340 Gene3D G3DSA:3.40.50.2300 58 174 7.7E-34 T 28-03-2018 CO689_RS06055 b86a9f50dd23f81609be8ac40ca17034 340 SUPERFAMILY SSF53822 67 336 4.17E-60 T 28-03-2018 IPR028082 Periplasmic binding protein-like I CO689_RS06055 b86a9f50dd23f81609be8ac40ca17034 340 ProSitePatterns PS00356 LacI-type HTH domain signature. 7 25 - T 28-03-2018 CO689_RS06055 b86a9f50dd23f81609be8ac40ca17034 340 Pfam PF00532 Periplasmic binding proteins and sugar binding domain of LacI family 66 324 9.0E-30 T 28-03-2018 IPR001761 Periplasmic binding protein/LacI sugar binding domain CO689_RS06055 b86a9f50dd23f81609be8ac40ca17034 340 Gene3D G3DSA:3.40.50.2300 175 315 1.3E-36 T 28-03-2018 CO689_RS06055 b86a9f50dd23f81609be8ac40ca17034 340 SUPERFAMILY SSF47413 4 63 1.46E-17 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CO689_RS06055 b86a9f50dd23f81609be8ac40ca17034 340 SMART SM00354 4 75 1.5E-30 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CO689_RS12650 4a1ba40e6e436b49cca293a9ef909263 295 SUPERFAMILY SSF47807 175 265 8.22E-27 T 28-03-2018 IPR020045 5'-3' exonuclease, C-terminal domain GO:0003677|GO:0003824 CO689_RS12650 4a1ba40e6e436b49cca293a9ef909263 295 Gene3D G3DSA:3.40.50.1010 3 187 6.8E-60 T 28-03-2018 IPR029060 PIN domain-like CO689_RS12650 4a1ba40e6e436b49cca293a9ef909263 295 Gene3D G3DSA:1.10.150.20 188 266 1.1E-24 T 28-03-2018 CO689_RS12650 4a1ba40e6e436b49cca293a9ef909263 295 SUPERFAMILY SSF88723 3 156 2.26E-48 T 28-03-2018 IPR029060 PIN domain-like CO689_RS12650 4a1ba40e6e436b49cca293a9ef909263 295 SMART SM00279 176 211 2.5E-11 T 28-03-2018 IPR008918 Helix-hairpin-helix motif, class 2 GO:0003677|GO:0003824 CO689_RS12650 4a1ba40e6e436b49cca293a9ef909263 295 Pfam PF02739 5'-3' exonuclease, N-terminal resolvase-like domain 4 161 7.5E-52 T 28-03-2018 IPR020046 5'-3' exonuclease, alpha-helical arch, N-terminal GO:0003677 CO689_RS12650 4a1ba40e6e436b49cca293a9ef909263 295 SMART SM00475 3 264 1.5E-105 T 28-03-2018 IPR002421 5'-3' exonuclease, N-terminal GO:0003677 CO689_RS12650 4a1ba40e6e436b49cca293a9ef909263 295 Pfam PF01367 5'-3' exonuclease, C-terminal SAM fold 175 257 5.4E-26 T 28-03-2018 IPR020045 5'-3' exonuclease, C-terminal domain GO:0003677|GO:0003824 CO689_RS09080 8820221c6def17da50023c9e45bef14f 213 SUPERFAMILY SSF54980 138 198 9.11E-9 T 28-03-2018 IPR035647 EF-G domain III/V-like CO689_RS09080 8820221c6def17da50023c9e45bef14f 213 Gene3D G3DSA:3.30.70.240 137 198 1.1E-12 T 28-03-2018 CO689_RS09080 8820221c6def17da50023c9e45bef14f 213 SUPERFAMILY SSF54211 4 131 1.02E-43 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CO689_RS09080 8820221c6def17da50023c9e45bef14f 213 Pfam PF01205 Uncharacterized protein family UPF0029 20 124 1.2E-33 T 28-03-2018 IPR001498 Impact, N-terminal CO689_RS09080 8820221c6def17da50023c9e45bef14f 213 Pfam PF09186 Domain of unknown function (DUF1949) 140 194 1.4E-11 T 28-03-2018 IPR015269 Uncharacterised domain UPF0029, Impact, C-terminal CO689_RS09080 8820221c6def17da50023c9e45bef14f 213 Gene3D G3DSA:3.30.230.30 4 133 9.6E-47 T 28-03-2018 IPR001498 Impact, N-terminal CO689_RS09080 8820221c6def17da50023c9e45bef14f 213 TIGRFAM TIGR00257 IMPACT_YIGZ: uncharacterized protein, YigZ family 5 200 7.5E-57 T 28-03-2018 IPR015796 Impact family, bacterial/archaeal CO689_RS08805 3b478cc7707471980d1eeee01c127e19 317 SUPERFAMILY SSF56327 143 308 1.17E-40 T 28-03-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 CO689_RS08805 3b478cc7707471980d1eeee01c127e19 317 SUPERFAMILY SSF51735 2 144 1.32E-29 T 28-03-2018 IPR016040 NAD(P)-binding domain CO689_RS08805 3b478cc7707471980d1eeee01c127e19 317 PIRSF PIRSF000102 1 316 3.0E-80 T 28-03-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 CO689_RS08805 3b478cc7707471980d1eeee01c127e19 317 Pfam PF00056 lactate/malate dehydrogenase, NAD binding domain 3 142 7.1E-24 T 28-03-2018 IPR001236 Lactate/malate dehydrogenase, N-terminal GO:0016491|GO:0055114 CO689_RS08805 3b478cc7707471980d1eeee01c127e19 317 PRINTS PR00086 L-lactate dehydrogenase signature 170 183 4.1E-25 T 28-03-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 CO689_RS08805 3b478cc7707471980d1eeee01c127e19 317 PRINTS PR00086 L-lactate dehydrogenase signature 117 137 4.1E-25 T 28-03-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 CO689_RS08805 3b478cc7707471980d1eeee01c127e19 317 PRINTS PR00086 L-lactate dehydrogenase signature 28 52 4.1E-25 T 28-03-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 CO689_RS08805 3b478cc7707471980d1eeee01c127e19 317 PRINTS PR00086 L-lactate dehydrogenase signature 140 158 4.1E-25 T 28-03-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 CO689_RS08805 3b478cc7707471980d1eeee01c127e19 317 PRINTS PR00086 L-lactate dehydrogenase signature 3 27 4.1E-25 T 28-03-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 CO689_RS08805 3b478cc7707471980d1eeee01c127e19 317 Pfam PF02866 lactate/malate dehydrogenase, alpha/beta C-terminal domain 145 311 2.2E-13 T 28-03-2018 IPR022383 Lactate/malate dehydrogenase, C-terminal GO:0016616|GO:0055114 CO689_RS08805 3b478cc7707471980d1eeee01c127e19 317 Gene3D G3DSA:3.40.50.720 4 143 4.7E-22 T 28-03-2018 CO689_RS08805 3b478cc7707471980d1eeee01c127e19 317 Gene3D G3DSA:3.90.110.10 144 315 3.1E-36 T 28-03-2018 CO689_RS10320 5352782e1134dd501cb9f546eafee062 391 SUPERFAMILY SSF53756 6 368 1.44E-40 T 28-03-2018 CO689_RS10320 5352782e1134dd501cb9f546eafee062 391 Pfam PF04101 Glycosyltransferase family 28 C-terminal domain 225 341 2.0E-13 T 28-03-2018 IPR007235 Glycosyl transferase, family 28, C-terminal GO:0016758 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193 CO689_RS10320 5352782e1134dd501cb9f546eafee062 391 Gene3D G3DSA:3.40.50.2000 1 193 6.2E-9 T 28-03-2018 CO689_RS10320 5352782e1134dd501cb9f546eafee062 391 Hamap MF_01280 Processive diacylglycerol beta-glucosyltransferase [ugtP]. 2 388 49.481 T 28-03-2018 IPR023589 Processive diacylglycerol beta-glucosyltransferase GO:0047228 KEGG: 00561+2.4.1.315|MetaCyc: PWY-6778|MetaCyc: PWY-7817 CO689_RS10320 5352782e1134dd501cb9f546eafee062 391 Gene3D G3DSA:3.40.50.2000 194 353 1.2E-25 T 28-03-2018 CO689_RS10320 5352782e1134dd501cb9f546eafee062 391 Pfam PF06925 Monogalactosyldiacylglycerol (MGDG) synthase 19 179 2.4E-42 T 28-03-2018 IPR009695 Diacylglycerol glucosyltransferase, N-terminal GO:0009247|GO:0016758 CO689_RS06105 9abdb01c77c9cf69ee4aa3d4024ff984 371 Pfam PF01380 SIS domain 49 182 2.7E-12 T 28-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 CO689_RS06105 9abdb01c77c9cf69ee4aa3d4024ff984 371 Gene3D G3DSA:3.40.50.10490 7 185 2.6E-22 T 28-03-2018 CO689_RS06105 9abdb01c77c9cf69ee4aa3d4024ff984 371 Gene3D G3DSA:3.40.50.10490 201 353 1.0E-14 T 28-03-2018 CO689_RS06105 9abdb01c77c9cf69ee4aa3d4024ff984 371 SUPERFAMILY SSF53697 6 360 4.33E-41 T 28-03-2018 CO689_RS02310 a6c646618ba4745ff3dc67405fa7f679 502 SMART SM00487 21 218 8.6E-60 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CO689_RS02310 a6c646618ba4745ff3dc67405fa7f679 502 Pfam PF00271 Helicase conserved C-terminal domain 226 335 2.4E-30 T 28-03-2018 IPR001650 Helicase, C-terminal CO689_RS02310 a6c646618ba4745ff3dc67405fa7f679 502 SUPERFAMILY SSF52540 69 356 2.7E-77 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CO689_RS02310 a6c646618ba4745ff3dc67405fa7f679 502 Gene3D G3DSA:3.40.50.300 8 218 2.1E-57 T 28-03-2018 CO689_RS02310 a6c646618ba4745ff3dc67405fa7f679 502 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 148 156 - T 28-03-2018 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site CO689_RS02310 a6c646618ba4745ff3dc67405fa7f679 502 Pfam PF00270 DEAD/DEAH box helicase 26 191 4.2E-49 T 28-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CO689_RS02310 a6c646618ba4745ff3dc67405fa7f679 502 Gene3D G3DSA:3.40.50.300 219 494 3.1E-45 T 28-03-2018 CO689_RS02310 a6c646618ba4745ff3dc67405fa7f679 502 SMART SM00490 254 335 5.3E-34 T 28-03-2018 IPR001650 Helicase, C-terminal CO689_RS03455 5695c127bff3587fe34f2ee4943e55e8 350 Pfam PF00296 Luciferase-like monooxygenase 25 305 2.2E-51 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CO689_RS03455 5695c127bff3587fe34f2ee4943e55e8 350 SUPERFAMILY SSF51679 18 345 4.32E-78 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CO689_RS03455 5695c127bff3587fe34f2ee4943e55e8 350 Gene3D G3DSA:3.20.20.30 2 348 1.1E-73 T 28-03-2018 CO689_RS03455 5695c127bff3587fe34f2ee4943e55e8 350 TIGRFAM TIGR03858 LLM_2I7G: probable oxidoreductase, LLM family 4 344 1.7E-153 T 28-03-2018 IPR022290 Conserved hypothetical protein CHP03858, luciferase-like monooxygenase, putative CO689_RS05180 e885aafd24348b41f976dd2ff7c6d18a 119 ProSitePatterns PS00846 Bacterial regulatory proteins, arsR family signature. 57 75 - T 28-03-2018 IPR018334 ArsR-type transcription regulator, HTH motif GO:0003700|GO:0005622|GO:0006355 CO689_RS05180 e885aafd24348b41f976dd2ff7c6d18a 119 SUPERFAMILY SSF46785 18 111 4.85E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS05180 e885aafd24348b41f976dd2ff7c6d18a 119 SMART SM00418 33 112 2.3E-20 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CO689_RS05180 e885aafd24348b41f976dd2ff7c6d18a 119 Pfam PF01022 Bacterial regulatory protein, arsR family 40 85 1.9E-13 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CO689_RS05180 e885aafd24348b41f976dd2ff7c6d18a 119 Gene3D G3DSA:1.10.10.10 1 119 7.3E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS05180 e885aafd24348b41f976dd2ff7c6d18a 119 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 83 98 3.1E-15 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CO689_RS05180 e885aafd24348b41f976dd2ff7c6d18a 119 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 68 83 3.1E-15 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CO689_RS05180 e885aafd24348b41f976dd2ff7c6d18a 119 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 55 66 3.1E-15 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CO689_RS05180 e885aafd24348b41f976dd2ff7c6d18a 119 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 35 50 3.1E-15 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CO689_RS11445 b31ffb3960f0c2e77d8bfef714cf8f1f 310 Gene3D G3DSA:3.40.50.170 1 205 1.8E-68 T 28-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CO689_RS11445 b31ffb3960f0c2e77d8bfef714cf8f1f 310 Pfam PF00551 Formyl transferase 3 178 5.6E-42 T 28-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CO689_RS11445 b31ffb3960f0c2e77d8bfef714cf8f1f 310 SUPERFAMILY SSF53328 3 205 2.22E-65 T 28-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CO689_RS11445 b31ffb3960f0c2e77d8bfef714cf8f1f 310 Pfam PF02911 Formyl transferase, C-terminal domain 203 301 1.7E-30 T 28-03-2018 IPR005793 Formyl transferase, C-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CO689_RS11445 b31ffb3960f0c2e77d8bfef714cf8f1f 310 TIGRFAM TIGR00460 fmt: methionyl-tRNA formyltransferase 3 304 7.0E-110 T 28-03-2018 IPR005794 Methionyl-tRNA formyltransferase GO:0004479|GO:0071951 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9|Reactome: R-HSA-5368286 CO689_RS11445 b31ffb3960f0c2e77d8bfef714cf8f1f 310 SUPERFAMILY SSF50486 204 301 1.54E-30 T 28-03-2018 IPR011034 Formyl transferase, C-terminal-like GO:0003824 CO689_RS11445 b31ffb3960f0c2e77d8bfef714cf8f1f 310 Hamap MF_00182 Methionyl-tRNA formyltransferase [fmt]. 2 303 36.573 T 28-03-2018 IPR005794 Methionyl-tRNA formyltransferase GO:0004479|GO:0071951 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9|Reactome: R-HSA-5368286 CO689_RS11445 b31ffb3960f0c2e77d8bfef714cf8f1f 310 Gene3D G3DSA:3.10.25.10 206 310 3.3E-32 T 28-03-2018 IPR005793 Formyl transferase, C-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CO689_RS07700 4ca4aad0048be9b211e6ab0238e00fce 274 TIGRFAM TIGR01743 purR_Bsub: pur operon repressor PurR 3 270 2.6E-109 T 28-03-2018 IPR010078 Pur operon repressor GO:0003677|GO:0045892|GO:0045982 CO689_RS07700 4ca4aad0048be9b211e6ab0238e00fce 274 Pfam PF09182 Bacterial purine repressor, N-terminal 4 73 7.4E-30 T 28-03-2018 IPR015265 Bacterial purine repressor, N-terminal GO:0003677|GO:0006355 CO689_RS07700 4ca4aad0048be9b211e6ab0238e00fce 274 ProDom PD029816 REPRESSOR OPERON PUR TRANSCRIPTION PURINE TRANSCRIPTIONAL PURR REGULATION DNA-BINDING GLYCOSYLTRANSFERASE 10 73 1.0E-25 T 28-03-2018 IPR015265 Bacterial purine repressor, N-terminal GO:0003677|GO:0006355 CO689_RS07700 4ca4aad0048be9b211e6ab0238e00fce 274 SUPERFAMILY SSF53271 93 259 1.61E-35 T 28-03-2018 IPR029057 Phosphoribosyltransferase-like CO689_RS07700 4ca4aad0048be9b211e6ab0238e00fce 274 SUPERFAMILY SSF46785 2 73 3.54E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS07700 4ca4aad0048be9b211e6ab0238e00fce 274 Gene3D G3DSA:3.40.50.2020 74 274 3.8E-31 T 28-03-2018 CO689_RS07700 4ca4aad0048be9b211e6ab0238e00fce 274 Pfam PF00156 Phosphoribosyl transferase domain 111 264 1.5E-20 T 28-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 CO689_RS07700 4ca4aad0048be9b211e6ab0238e00fce 274 Gene3D G3DSA:1.10.10.10 1 73 6.7E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS13090 85b741cad58fbf54335cd02b67d73ef1 177 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 42 62 4.5E-4 T 28-03-2018 IPR012902 Prokaryotic N-terminal methylation site CO689_RS13090 85b741cad58fbf54335cd02b67d73ef1 177 Pfam PF15980 Putative Competence protein ComGF 71 169 6.2E-9 T 28-03-2018 IPR016977 Competence operon G, ComGF CO689_RS08160 bdd24d6a59a9d51b696323fe728e58a4 166 SUPERFAMILY SSF53927 2 153 1.17E-55 T 28-03-2018 IPR016193 Cytidine deaminase-like GO:0003824 CO689_RS08160 bdd24d6a59a9d51b696323fe728e58a4 166 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 53 90 - T 28-03-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 CO689_RS08160 bdd24d6a59a9d51b696323fe728e58a4 166 Gene3D G3DSA:3.40.140.10 1 159 2.7E-52 T 28-03-2018 CO689_RS08160 bdd24d6a59a9d51b696323fe728e58a4 166 Hamap MF_00972 tRNA-specific adenosine deaminase [tadA]. 8 149 47.068 T 28-03-2018 IPR028883 tRNA-specific adenosine deaminase GO:0002100|GO:0008251 Reactome: R-HSA-6782315 CO689_RS08160 bdd24d6a59a9d51b696323fe728e58a4 166 Pfam PF14437 MafB19-like deaminase 4 149 3.1E-44 T 28-03-2018 IPR028883 tRNA-specific adenosine deaminase GO:0002100|GO:0008251 Reactome: R-HSA-6782315 CO689_RS08855 81f4830ec570f4c25f797c0550f3dce7 344 Gene3D G3DSA:3.30.565.10 191 343 6.3E-37 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CO689_RS08855 81f4830ec570f4c25f797c0550f3dce7 344 Pfam PF00512 His Kinase A (phospho-acceptor) domain 123 187 1.5E-10 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CO689_RS08855 81f4830ec570f4c25f797c0550f3dce7 344 SMART SM00388 121 188 1.3E-9 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CO689_RS08855 81f4830ec570f4c25f797c0550f3dce7 344 PRINTS PR00344 Bacterial sensor protein C-terminal signature 270 284 2.7E-14 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CO689_RS08855 81f4830ec570f4c25f797c0550f3dce7 344 PRINTS PR00344 Bacterial sensor protein C-terminal signature 288 298 2.7E-14 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CO689_RS08855 81f4830ec570f4c25f797c0550f3dce7 344 PRINTS PR00344 Bacterial sensor protein C-terminal signature 305 323 2.7E-14 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CO689_RS08855 81f4830ec570f4c25f797c0550f3dce7 344 PRINTS PR00344 Bacterial sensor protein C-terminal signature 329 342 2.7E-14 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CO689_RS08855 81f4830ec570f4c25f797c0550f3dce7 344 SUPERFAMILY SSF55874 190 343 3.64E-38 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CO689_RS08855 81f4830ec570f4c25f797c0550f3dce7 344 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 235 343 1.5E-23 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CO689_RS08855 81f4830ec570f4c25f797c0550f3dce7 344 Gene3D G3DSA:1.10.287.130 111 183 4.6E-13 T 28-03-2018 CO689_RS08855 81f4830ec570f4c25f797c0550f3dce7 344 SUPERFAMILY SSF47384 104 188 2.75E-13 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CO689_RS08855 81f4830ec570f4c25f797c0550f3dce7 344 SMART SM00387 233 344 3.0E-28 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CO689_RS04070 3cf16cd108eae4537210a392edcedca6 398 Gene3D G3DSA:1.20.1250.20 1 197 8.5E-30 T 28-03-2018 CO689_RS04070 3cf16cd108eae4537210a392edcedca6 398 TIGRFAM TIGR00710 efflux_Bcr_CflA: drug resistance transporter, Bcr/CflA subfamily 12 387 5.3E-76 T 28-03-2018 IPR004812 Drug resistance transporter Bcr/CmlA subfamily GO:0005215|GO:0006810|GO:0016021 CO689_RS04070 3cf16cd108eae4537210a392edcedca6 398 Gene3D G3DSA:1.20.1250.20 201 393 1.8E-11 T 28-03-2018 CO689_RS04070 3cf16cd108eae4537210a392edcedca6 398 SUPERFAMILY SSF103473 7 391 3.53E-54 T 28-03-2018 IPR020846 Major facilitator superfamily domain CO689_RS04070 3cf16cd108eae4537210a392edcedca6 398 Pfam PF07690 Major Facilitator Superfamily 21 360 2.4E-34 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CO689_RS04205 f81cf50ef1a69d6768c7a65cbcd96ed6 509 Pfam PF02541 Ppx/GppA phosphatase family 18 302 1.4E-50 T 28-03-2018 IPR003695 Ppx/GppA phosphatase KEGG: 00230+3.6.1.40 CO689_RS04205 f81cf50ef1a69d6768c7a65cbcd96ed6 509 SUPERFAMILY SSF109604 314 507 1.98E-25 T 28-03-2018 CO689_RS04205 f81cf50ef1a69d6768c7a65cbcd96ed6 509 Gene3D G3DSA:3.30.420.150 126 308 4.4E-42 T 28-03-2018 CO689_RS04205 f81cf50ef1a69d6768c7a65cbcd96ed6 509 Gene3D G3DSA:3.30.420.40 1 125 2.2E-31 T 28-03-2018 CO689_RS04205 f81cf50ef1a69d6768c7a65cbcd96ed6 509 SUPERFAMILY SSF53067 3 124 3.88E-27 T 28-03-2018 CO689_RS04205 f81cf50ef1a69d6768c7a65cbcd96ed6 509 TIGRFAM TIGR03706 exo_poly_only: exopolyphosphatase 3 302 1.7E-93 T 28-03-2018 IPR022371 Exopolyphosphatase GO:0004309|GO:0006793 CO689_RS04205 f81cf50ef1a69d6768c7a65cbcd96ed6 509 SUPERFAMILY SSF53067 129 305 2.59E-40 T 28-03-2018 CO689_RS05425 e3713cd6615a7e7963367a3dafbe8a32 280 Pfam PF03180 NLPA lipoprotein 27 263 1.9E-82 T 28-03-2018 IPR004872 Lipoprotein NlpA family CO689_RS05425 e3713cd6615a7e7963367a3dafbe8a32 280 PIRSF PIRSF002854 1 267 4.2E-87 T 28-03-2018 IPR004872 Lipoprotein NlpA family CO689_RS05425 e3713cd6615a7e7963367a3dafbe8a32 280 SUPERFAMILY SSF53850 26 277 2.61E-79 T 28-03-2018 CO689_RS05425 e3713cd6615a7e7963367a3dafbe8a32 280 Gene3D G3DSA:3.40.190.10 23 115 1.5E-18 T 28-03-2018 CO689_RS05425 e3713cd6615a7e7963367a3dafbe8a32 280 Gene3D G3DSA:3.40.190.10 116 214 9.0E-42 T 28-03-2018 CO689_RS13625 0790ca5776afc120788ccf1cc263202f 243 SMART SM00650 18 180 4.4E-67 T 28-03-2018 IPR020598 Ribosomal RNA adenine methylase transferase, N-terminal GO:0000154|GO:0000179|GO:0008649 CO689_RS13625 0790ca5776afc120788ccf1cc263202f 243 SUPERFAMILY SSF53335 10 241 8.73E-52 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CO689_RS13625 0790ca5776afc120788ccf1cc263202f 243 ProSitePatterns PS01131 Ribosomal RNA adenine dimethylases signature. 34 61 - T 28-03-2018 IPR020596 Ribosomal RNA adenine methylase transferase, conserved site GO:0000154|GO:0000179|GO:0008649 CO689_RS13625 0790ca5776afc120788ccf1cc263202f 243 Gene3D G3DSA:1.10.8.100 185 243 1.0E-33 T 28-03-2018 IPR023165 rRNA adenine dimethylase-like Reactome: R-HSA-2151201|Reactome: R-HSA-6793080 CO689_RS13625 0790ca5776afc120788ccf1cc263202f 243 Gene3D G3DSA:3.40.50.150 2 184 6.7E-34 T 28-03-2018 CO689_RS13625 0790ca5776afc120788ccf1cc263202f 243 Pfam PF00398 Ribosomal RNA adenine dimethylase 1 239 2.2E-75 T 28-03-2018 IPR001737 Ribosomal RNA adenine methyltransferase KsgA/Erm CO689_RS09865 884dd219b9a5ac8d49aeffb33fc00e52 439 SUPERFAMILY SSF56300 2 259 1.19E-56 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CO689_RS09865 884dd219b9a5ac8d49aeffb33fc00e52 439 SUPERFAMILY SSF55816 283 436 4.71E-21 T 28-03-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CO689_RS09865 884dd219b9a5ac8d49aeffb33fc00e52 439 Pfam PF00149 Calcineurin-like phosphoesterase 3 200 1.0E-6 T 28-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 CO689_RS09865 884dd219b9a5ac8d49aeffb33fc00e52 439 PRINTS PR01607 Apyrase family signature 1 15 5.8E-17 T 28-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CO689_RS09865 884dd219b9a5ac8d49aeffb33fc00e52 439 PRINTS PR01607 Apyrase family signature 315 338 5.8E-17 T 28-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CO689_RS09865 884dd219b9a5ac8d49aeffb33fc00e52 439 PRINTS PR01607 Apyrase family signature 163 180 5.8E-17 T 28-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CO689_RS09865 884dd219b9a5ac8d49aeffb33fc00e52 439 PRINTS PR01607 Apyrase family signature 210 230 5.8E-17 T 28-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CO689_RS09865 884dd219b9a5ac8d49aeffb33fc00e52 439 PRINTS PR01607 Apyrase family signature 182 205 5.8E-17 T 28-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CO689_RS09865 884dd219b9a5ac8d49aeffb33fc00e52 439 Gene3D G3DSA:3.90.780.10 275 439 3.0E-20 T 28-03-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CO689_RS09865 884dd219b9a5ac8d49aeffb33fc00e52 439 Pfam PF02872 5'-nucleotidase, C-terminal domain 282 403 8.2E-7 T 28-03-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CO689_RS09865 884dd219b9a5ac8d49aeffb33fc00e52 439 PIRSF PIRSF036361 1 439 5.1E-174 T 28-03-2018 IPR011240 Phosphoesterase-related protein YunD CO689_RS09865 884dd219b9a5ac8d49aeffb33fc00e52 439 Gene3D G3DSA:3.60.21.10 1 274 3.0E-46 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CO689_RS00810 ee5f87f1a09657397fe7474e7e1d8c3f 87 SUPERFAMILY SSF49401 17 84 1.49E-13 T 28-03-2018 IPR008966 Adhesion domain CO689_RS00810 ee5f87f1a09657397fe7474e7e1d8c3f 87 Gene3D G3DSA:2.60.40.1290 16 87 1.1E-14 T 28-03-2018 CO689_RS00810 ee5f87f1a09657397fe7474e7e1d8c3f 87 Pfam PF10425 C-terminus of bacterial fibrinogen-binding adhesin 21 83 3.3E-11 T 28-03-2018 IPR011266 Fibrinogen-binding domain 2 GO:0005618|GO:0007155 CO689_RS05925 dfe7534ce10811d02ec4ddece3feec81 377 Gene3D G3DSA:3.90.230.10 142 376 1.4E-56 T 28-03-2018 CO689_RS05925 dfe7534ce10811d02ec4ddece3feec81 377 Gene3D G3DSA:3.40.350.10 3 141 1.0E-11 T 28-03-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal CO689_RS05925 dfe7534ce10811d02ec4ddece3feec81 377 Pfam PF00557 Metallopeptidase family M24 151 358 4.7E-45 T 28-03-2018 IPR000994 Peptidase M24 CO689_RS05925 dfe7534ce10811d02ec4ddece3feec81 377 Pfam PF01321 Creatinase/Prolidase N-terminal domain 6 137 7.6E-14 T 28-03-2018 IPR000587 Creatinase, N-terminal GO:0016787 CO689_RS05925 dfe7534ce10811d02ec4ddece3feec81 377 SUPERFAMILY SSF55920 141 374 1.02E-59 T 28-03-2018 IPR000994 Peptidase M24 CO689_RS05925 dfe7534ce10811d02ec4ddece3feec81 377 SUPERFAMILY SSF53092 4 141 9.07E-22 T 28-03-2018 IPR028980 Creatinase/Aminopeptidase P, N-terminal CO689_RS00610 ab58a1c65c4a1ada3175794bb0be3f36 207 TIGRFAM TIGR03128 RuMP_HxlA: 3-hexulose-6-phosphate synthase 1 202 2.3E-74 T 28-03-2018 IPR017553 3-hexulose-6-phosphate synthase GO:0005975|GO:0043801 KEGG: 00030+4.1.2.43|KEGG: 00680+4.1.2.43|MetaCyc: PWY-1861|MetaCyc: PWY-7796 CO689_RS00610 ab58a1c65c4a1ada3175794bb0be3f36 207 SUPERFAMILY SSF51366 1 203 4.71E-35 T 28-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 CO689_RS00610 ab58a1c65c4a1ada3175794bb0be3f36 207 Gene3D G3DSA:3.20.20.70 1 204 1.5E-31 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CO689_RS00610 ab58a1c65c4a1ada3175794bb0be3f36 207 SMART SM00934 1 199 9.8E-19 T 28-03-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CO689_RS00610 ab58a1c65c4a1ada3175794bb0be3f36 207 Pfam PF00215 Orotidine 5'-phosphate decarboxylase / HUMPS family 1 198 3.5E-23 T 28-03-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CO689_RS12185 ff8f3a0a23cc1dd191742e7a7fa6ce8d 662 Gene3D G3DSA:3.40.50.970 3 358 5.0E-103 T 28-03-2018 CO689_RS12185 ff8f3a0a23cc1dd191742e7a7fa6ce8d 662 TIGRFAM TIGR00232 tktlase_bact: transketolase 9 660 9.4E-280 T 28-03-2018 IPR005478 Transketolase, bacterial-like GO:0004802 KEGG: 00030+2.2.1.1|KEGG: 00710+2.2.1.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|MetaCyc: PWY-6901 CO689_RS12185 ff8f3a0a23cc1dd191742e7a7fa6ce8d 662 Gene3D G3DSA:3.40.50.920 538 661 2.8E-25 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CO689_RS12185 ff8f3a0a23cc1dd191742e7a7fa6ce8d 662 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 7 337 7.5E-145 T 28-03-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 CO689_RS12185 ff8f3a0a23cc1dd191742e7a7fa6ce8d 662 SUPERFAMILY SSF52518 6 324 2.24E-111 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CO689_RS12185 ff8f3a0a23cc1dd191742e7a7fa6ce8d 662 SMART SM00861 353 524 3.6E-60 T 28-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain CO689_RS12185 ff8f3a0a23cc1dd191742e7a7fa6ce8d 662 SUPERFAMILY SSF52922 534 660 9.16E-37 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CO689_RS12185 ff8f3a0a23cc1dd191742e7a7fa6ce8d 662 SUPERFAMILY SSF52518 341 525 7.97E-63 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CO689_RS12185 ff8f3a0a23cc1dd191742e7a7fa6ce8d 662 ProSitePatterns PS00801 Transketolase signature 1. 14 34 - T 28-03-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 CO689_RS12185 ff8f3a0a23cc1dd191742e7a7fa6ce8d 662 Pfam PF02779 Transketolase, pyrimidine binding domain 354 523 1.9E-40 T 28-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain CO689_RS12185 ff8f3a0a23cc1dd191742e7a7fa6ce8d 662 Gene3D G3DSA:3.40.50.970 359 532 5.0E-42 T 28-03-2018 CO689_RS12185 ff8f3a0a23cc1dd191742e7a7fa6ce8d 662 ProSitePatterns PS00802 Transketolase signature 2. 466 482 - T 28-03-2018 IPR020826 Transketolase binding site KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 CO689_RS09390 387e1719dadf8be1273d630152e252d0 270 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 71 82 2.1E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CO689_RS09390 387e1719dadf8be1273d630152e252d0 270 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 124 132 2.1E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CO689_RS09390 387e1719dadf8be1273d630152e252d0 270 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 144 163 2.1E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CO689_RS09390 387e1719dadf8be1273d630152e252d0 270 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 165 182 5.7E-25 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CO689_RS09390 387e1719dadf8be1273d630152e252d0 270 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 144 163 5.7E-25 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CO689_RS09390 387e1719dadf8be1273d630152e252d0 270 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 118 134 5.7E-25 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CO689_RS09390 387e1719dadf8be1273d630152e252d0 270 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 5 22 5.7E-25 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CO689_RS09390 387e1719dadf8be1273d630152e252d0 270 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 71 82 5.7E-25 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CO689_RS09390 387e1719dadf8be1273d630152e252d0 270 Pfam PF00106 short chain dehydrogenase 4 181 5.6E-51 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CO689_RS09390 387e1719dadf8be1273d630152e252d0 270 SUPERFAMILY SSF51735 3 246 7.47E-65 T 28-03-2018 IPR016040 NAD(P)-binding domain CO689_RS09390 387e1719dadf8be1273d630152e252d0 270 Gene3D G3DSA:3.40.50.720 1 255 8.4E-65 T 28-03-2018 CO689_RS11065 df01e0ac1fe3977566d7b359f70cb550 88 Pfam PF05164 Cell division protein ZapA 8 83 8.4E-16 T 28-03-2018 IPR007838 Cell division protein ZapA-like CO689_RS11065 df01e0ac1fe3977566d7b359f70cb550 88 SUPERFAMILY SSF102829 7 85 1.44E-19 T 28-03-2018 IPR007838 Cell division protein ZapA-like CO689_RS10185 245238790448dbbbc7a5c31cdaf6b6f3 555 Gene3D G3DSA:3.40.190.10 204 296 1.0E-17 T 28-03-2018 CO689_RS10185 245238790448dbbbc7a5c31cdaf6b6f3 555 Gene3D G3DSA:3.10.105.10 297 511 1.7E-47 T 28-03-2018 CO689_RS10185 245238790448dbbbc7a5c31cdaf6b6f3 555 PIRSF PIRSF002741 1 542 4.5E-97 T 28-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 CO689_RS10185 245238790448dbbbc7a5c31cdaf6b6f3 555 Gene3D G3DSA:3.90.76.10 43 203 1.8E-37 T 28-03-2018 CO689_RS10185 245238790448dbbbc7a5c31cdaf6b6f3 555 SUPERFAMILY SSF53850 32 531 2.17E-117 T 28-03-2018 CO689_RS10185 245238790448dbbbc7a5c31cdaf6b6f3 555 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 78 460 1.1E-72 T 28-03-2018 IPR000914 Solute-binding protein family 5 domain CO689_RS07595 5805e9f9b11531bc82decdf8b1547613 85 Pfam PF01541 GIY-YIG catalytic domain 5 76 5.6E-19 T 28-03-2018 IPR000305 GIY-YIG nuclease superfamily CO689_RS07595 5805e9f9b11531bc82decdf8b1547613 85 SUPERFAMILY SSF82771 5 74 1.57E-14 T 28-03-2018 IPR000305 GIY-YIG nuclease superfamily CO689_RS07595 5805e9f9b11531bc82decdf8b1547613 85 SMART SM00465 4 83 0.0075 T 28-03-2018 IPR000305 GIY-YIG nuclease superfamily CO689_RS07595 5805e9f9b11531bc82decdf8b1547613 85 Gene3D G3DSA:3.40.1440.10 1 82 6.7E-10 T 28-03-2018 IPR000305 GIY-YIG nuclease superfamily CO689_RS13470 c5ef455fe77f821863f9f96f163ed230 139 TIGRFAM TIGR00738 rrf2_super: Rrf2 family protein 1 124 1.8E-31 T 28-03-2018 IPR000944 Transcription regulator Rrf2-type CO689_RS13470 c5ef455fe77f821863f9f96f163ed230 139 ProSitePatterns PS01332 Rrf2-type HTH domain signature. 49 67 - T 28-03-2018 IPR030489 Transcription regulator Rrf2-type, conserved site CO689_RS13470 c5ef455fe77f821863f9f96f163ed230 139 SUPERFAMILY SSF46785 2 125 4.39E-28 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS13470 c5ef455fe77f821863f9f96f163ed230 139 Pfam PF02082 Transcriptional regulator 1 82 2.1E-26 T 28-03-2018 IPR000944 Transcription regulator Rrf2-type CO689_RS13470 c5ef455fe77f821863f9f96f163ed230 139 Gene3D G3DSA:1.10.10.10 1 139 8.9E-28 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS10545 f5dd438ea53538fcb63c2e8cc43667e9 387 Gene3D G3DSA:3.40.640.10 44 268 2.4E-52 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CO689_RS10545 f5dd438ea53538fcb63c2e8cc43667e9 387 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 229 242 - T 28-03-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 CO689_RS10545 f5dd438ea53538fcb63c2e8cc43667e9 387 Gene3D G3DSA:3.90.1150.10 269 387 2.3E-24 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CO689_RS10545 f5dd438ea53538fcb63c2e8cc43667e9 387 SUPERFAMILY SSF53383 23 385 3.12E-106 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CO689_RS10545 f5dd438ea53538fcb63c2e8cc43667e9 387 Pfam PF00155 Aminotransferase class I and II 29 378 2.2E-55 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CO689_RS09090 6dd65bb4d99b8cf018599f3a64007ed7 435 SMART SM00490 315 393 6.9E-8 T 28-03-2018 IPR001650 Helicase, C-terminal CO689_RS09090 6dd65bb4d99b8cf018599f3a64007ed7 435 Pfam PF04851 Type III restriction enzyme, res subunit 98 246 3.4E-11 T 28-03-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 CO689_RS09090 6dd65bb4d99b8cf018599f3a64007ed7 435 Gene3D G3DSA:3.40.50.300 274 427 1.2E-18 T 28-03-2018 CO689_RS09090 6dd65bb4d99b8cf018599f3a64007ed7 435 SUPERFAMILY SSF52540 111 404 2.64E-37 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CO689_RS09090 6dd65bb4d99b8cf018599f3a64007ed7 435 Pfam PF00271 Helicase conserved C-terminal domain 287 391 8.8E-11 T 28-03-2018 IPR001650 Helicase, C-terminal CO689_RS09090 6dd65bb4d99b8cf018599f3a64007ed7 435 SMART SM00487 96 278 5.2E-12 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CO689_RS09090 6dd65bb4d99b8cf018599f3a64007ed7 435 Gene3D G3DSA:3.40.50.300 97 269 3.0E-19 T 28-03-2018 CO689_RS04875 194cafeb11bcaaf09c4937669ea32b35 190 Gene3D G3DSA:3.20.20.70 3 178 2.4E-10 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CO689_RS04875 194cafeb11bcaaf09c4937669ea32b35 190 SUPERFAMILY SSF51391 25 176 3.53E-23 T 28-03-2018 IPR022998 Thiamine phosphate synthase/TenI KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CO689_RS04875 194cafeb11bcaaf09c4937669ea32b35 190 Pfam PF02581 Thiamine monophosphate synthase 33 170 2.5E-17 T 28-03-2018 IPR022998 Thiamine phosphate synthase/TenI KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CO689_RS06250 4a4f178f8f282c5c94e75a905f40b248 497 PRINTS PR00067 Catalase signature 85 103 1.1E-71 T 28-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CO689_RS06250 4a4f178f8f282c5c94e75a905f40b248 497 PRINTS PR00067 Catalase signature 125 143 1.1E-71 T 28-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CO689_RS06250 4a4f178f8f282c5c94e75a905f40b248 497 PRINTS PR00067 Catalase signature 322 348 1.1E-71 T 28-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CO689_RS06250 4a4f178f8f282c5c94e75a905f40b248 497 PRINTS PR00067 Catalase signature 106 123 1.1E-71 T 28-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CO689_RS06250 4a4f178f8f282c5c94e75a905f40b248 497 PRINTS PR00067 Catalase signature 22 45 1.1E-71 T 28-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CO689_RS06250 4a4f178f8f282c5c94e75a905f40b248 497 PRINTS PR00067 Catalase signature 290 317 1.1E-71 T 28-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CO689_RS06250 4a4f178f8f282c5c94e75a905f40b248 497 SMART SM01060 9 398 2.4E-269 T 28-03-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CO689_RS06250 4a4f178f8f282c5c94e75a905f40b248 497 SUPERFAMILY SSF56634 3 492 1.22E-201 T 28-03-2018 IPR020835 Catalase-like domain GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CO689_RS06250 4a4f178f8f282c5c94e75a905f40b248 497 Gene3D G3DSA:2.40.180.10 1 359 1.7E-158 T 28-03-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CO689_RS06250 4a4f178f8f282c5c94e75a905f40b248 497 PIRSF PIRSF038928 1 489 1.5E-210 T 28-03-2018 IPR024711 Catalase, mono-functional, haem-containing, clades 1 and 3 GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CO689_RS06250 4a4f178f8f282c5c94e75a905f40b248 497 ProSitePatterns PS00438 Catalase proximal active site signature. 45 61 - T 28-03-2018 IPR024708 Catalase active site GO:0004096 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CO689_RS06250 4a4f178f8f282c5c94e75a905f40b248 497 Pfam PF00199 Catalase 12 394 7.8E-182 T 28-03-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CO689_RS06250 4a4f178f8f282c5c94e75a905f40b248 497 Pfam PF06628 Catalase-related immune-responsive 422 483 1.7E-23 T 28-03-2018 IPR010582 Catalase immune-responsive domain KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CO689_RS06250 4a4f178f8f282c5c94e75a905f40b248 497 ProSitePatterns PS00437 Catalase proximal heme-ligand signature. 335 343 - T 28-03-2018 IPR002226 Catalase haem-binding site GO:0020037 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CO689_RS06675 cfcc2fd3800c6abec85a9e528783aa35 666 TIGRFAM TIGR00976 /NonD: hydrolase CocE/NonD family protein 30 317 8.0E-41 T 28-03-2018 IPR005674 CocE/Serine esterase GO:0016787 CO689_RS06675 cfcc2fd3800c6abec85a9e528783aa35 666 Pfam PF02129 X-Pro dipeptidyl-peptidase (S15 family) 33 282 1.0E-56 T 28-03-2018 IPR000383 Xaa-Pro dipeptidyl-peptidase-like domain GO:0016787 CO689_RS06675 cfcc2fd3800c6abec85a9e528783aa35 666 SMART SM00939 301 521 6.6E-28 T 28-03-2018 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 CO689_RS06675 cfcc2fd3800c6abec85a9e528783aa35 666 Gene3D G3DSA:3.40.50.1820 9 330 6.9E-37 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CO689_RS06675 cfcc2fd3800c6abec85a9e528783aa35 666 Gene3D G3DSA:2.60.120.260 331 525 3.1E-28 T 28-03-2018 IPR008979 Galactose-binding domain-like CO689_RS06675 cfcc2fd3800c6abec85a9e528783aa35 666 Pfam PF08530 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain 386 518 9.0E-29 T 28-03-2018 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 CO689_RS06675 cfcc2fd3800c6abec85a9e528783aa35 666 SUPERFAMILY SSF49785 368 526 8.93E-31 T 28-03-2018 IPR008979 Galactose-binding domain-like CO689_RS06675 cfcc2fd3800c6abec85a9e528783aa35 666 SUPERFAMILY SSF53474 15 309 1.72E-64 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CO689_RS07730 1b4c6ec400825b8facbdf791fe583209 190 TIGRFAM TIGR00447 pth: aminoacyl-tRNA hydrolase 1 186 1.8E-65 T 28-03-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 CO689_RS07730 1b4c6ec400825b8facbdf791fe583209 190 SUPERFAMILY SSF53178 1 186 6.67E-67 T 28-03-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 CO689_RS07730 1b4c6ec400825b8facbdf791fe583209 190 ProSitePatterns PS01195 Peptidyl-tRNA hydrolase signature 1. 14 27 - T 28-03-2018 IPR018171 Peptidyl-tRNA hydrolase, conserved site GO:0004045 MetaCyc: PWY-6308 CO689_RS07730 1b4c6ec400825b8facbdf791fe583209 190 Gene3D G3DSA:3.40.50.1470 1 190 1.0E-71 T 28-03-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 CO689_RS07730 1b4c6ec400825b8facbdf791fe583209 190 Pfam PF01195 Peptidyl-tRNA hydrolase 4 186 4.4E-58 T 28-03-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 CO689_RS07730 1b4c6ec400825b8facbdf791fe583209 190 Hamap MF_00083 Peptidyl-tRNA hydrolase [pth]. 1 178 36.637 T 28-03-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 CO689_RS07730 1b4c6ec400825b8facbdf791fe583209 190 ProSitePatterns PS01196 Peptidyl-tRNA hydrolase signature 2. 107 117 - T 28-03-2018 IPR018171 Peptidyl-tRNA hydrolase, conserved site GO:0004045 MetaCyc: PWY-6308 CO689_RS11570 02c99d255b95552a267ca63fbd124e0b 167 Gene3D G3DSA:2.30.30.240 93 159 4.2E-21 T 28-03-2018 CO689_RS11570 02c99d255b95552a267ca63fbd124e0b 167 Gene3D G3DSA:2.40.30.60 2 88 2.0E-22 T 28-03-2018 IPR002676 RimM protein GO:0006364 CO689_RS11570 02c99d255b95552a267ca63fbd124e0b 167 SUPERFAMILY SSF50346 97 163 7.85E-18 T 28-03-2018 IPR011033 PRC-barrel-like CO689_RS11570 02c99d255b95552a267ca63fbd124e0b 167 Hamap MF_00014 Ribosome maturation factor RimM [rimM]. 2 164 24.488 T 28-03-2018 IPR011961 16S rRNA processing protein RimM GO:0005840|GO:0006364|GO:0043022 CO689_RS11570 02c99d255b95552a267ca63fbd124e0b 167 SUPERFAMILY SSF50447 3 86 3.35E-21 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain CO689_RS11570 02c99d255b95552a267ca63fbd124e0b 167 TIGRFAM TIGR02273 16S_RimM: 16S rRNA processing protein RimM 3 163 1.0E-46 T 28-03-2018 IPR011961 16S rRNA processing protein RimM GO:0005840|GO:0006364|GO:0043022 CO689_RS11570 02c99d255b95552a267ca63fbd124e0b 167 Pfam PF05239 PRC-barrel domain 95 163 9.8E-12 T 28-03-2018 IPR027275 PRC-barrel domain CO689_RS11570 02c99d255b95552a267ca63fbd124e0b 167 Pfam PF01782 RimM N-terminal domain 4 86 4.1E-24 T 28-03-2018 IPR002676 RimM protein GO:0006364 CO689_RS13685 ec21efccef38f881e3c208233cc860ec 213 ProSitePatterns PS01333 Pyrrolidone-carboxylate peptidase glutamic acid active site. 67 83 - T 28-03-2018 IPR033693 Pyroglutamyl peptidase I, Glu active site CO689_RS13685 ec21efccef38f881e3c208233cc860ec 213 Gene3D G3DSA:3.40.630.20 1 213 1.5E-56 T 28-03-2018 IPR016125 Peptidase C15, pyroglutamyl peptidase I-like CO689_RS13685 ec21efccef38f881e3c208233cc860ec 213 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 78 98 1.9E-41 T 28-03-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 CO689_RS13685 ec21efccef38f881e3c208233cc860ec 213 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 60 72 1.9E-41 T 28-03-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 CO689_RS13685 ec21efccef38f881e3c208233cc860ec 213 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 160 172 1.9E-41 T 28-03-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 CO689_RS13685 ec21efccef38f881e3c208233cc860ec 213 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 3 26 1.9E-41 T 28-03-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 CO689_RS13685 ec21efccef38f881e3c208233cc860ec 213 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 130 146 1.9E-41 T 28-03-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 CO689_RS13685 ec21efccef38f881e3c208233cc860ec 213 Pfam PF01470 Pyroglutamyl peptidase 1 197 1.2E-84 T 28-03-2018 IPR016125 Peptidase C15, pyroglutamyl peptidase I-like CO689_RS13685 ec21efccef38f881e3c208233cc860ec 213 ProSitePatterns PS01334 Pyrrolidone-carboxylate peptidase cysteine active site. 128 142 - T 28-03-2018 IPR033694 Pyroglutamyl peptidase I, Cys active site CO689_RS13685 ec21efccef38f881e3c208233cc860ec 213 TIGRFAM TIGR00504 pyro_pdase: pyroglutamyl-peptidase I 3 200 3.4E-70 T 28-03-2018 IPR029762 Pyroglutamyl peptidase I, bacterial-type GO:0005829|GO:0006508|GO:0008234|GO:0016920 CO689_RS13685 ec21efccef38f881e3c208233cc860ec 213 PIRSF PIRSF015592 1 211 5.5E-76 T 28-03-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 CO689_RS13685 ec21efccef38f881e3c208233cc860ec 213 Hamap MF_00417 Pyrrolidone-carboxylate peptidase [pcp]. 1 199 36.163 T 28-03-2018 IPR029762 Pyroglutamyl peptidase I, bacterial-type GO:0005829|GO:0006508|GO:0008234|GO:0016920 CO689_RS13685 ec21efccef38f881e3c208233cc860ec 213 SUPERFAMILY SSF53182 1 208 2.49E-62 T 28-03-2018 IPR016125 Peptidase C15, pyroglutamyl peptidase I-like CO689_RS10125 28b120f19bb75e06fb5917a1c3cd5b29 281 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 5 235 1.8E-25 T 28-03-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 CO689_RS10125 28b120f19bb75e06fb5917a1c3cd5b29 281 Pfam PF08282 haloacid dehalogenase-like hydrolase 6 262 3.5E-62 T 28-03-2018 IPR023214 HAD-like domain CO689_RS10125 28b120f19bb75e06fb5917a1c3cd5b29 281 ProSitePatterns PS01228 Hypothetical cof family signature 1. 5 16 - T 28-03-2018 CO689_RS10125 28b120f19bb75e06fb5917a1c3cd5b29 281 SUPERFAMILY SSF56784 1 266 9.49E-67 T 28-03-2018 IPR023214 HAD-like domain CO689_RS10125 28b120f19bb75e06fb5917a1c3cd5b29 281 Gene3D G3DSA:3.40.50.1000 2 257 8.9E-36 T 28-03-2018 IPR023214 HAD-like domain CO689_RS10125 28b120f19bb75e06fb5917a1c3cd5b29 281 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 5 262 1.6E-57 T 28-03-2018 IPR000150 Cof family GO:0016787 CO689_RS12315 e0bc8566319624fdb1eb0ba99c4f63c5 346 SUPERFAMILY SSF53187 4 83 3.27E-55 T 28-03-2018 CO689_RS12315 e0bc8566319624fdb1eb0ba99c4f63c5 346 SUPERFAMILY SSF53187 178 340 3.27E-55 T 28-03-2018 CO689_RS12315 e0bc8566319624fdb1eb0ba99c4f63c5 346 Gene3D G3DSA:3.40.630.10 1 341 9.8E-43 T 28-03-2018 CO689_RS12315 e0bc8566319624fdb1eb0ba99c4f63c5 346 PIRSF PIRSF001123 2 344 1.5E-40 T 28-03-2018 IPR008007 Peptidase M42 CO689_RS12315 e0bc8566319624fdb1eb0ba99c4f63c5 346 Pfam PF05343 M42 glutamyl aminopeptidase 46 334 4.3E-86 T 28-03-2018 IPR008007 Peptidase M42 CO689_RS12315 e0bc8566319624fdb1eb0ba99c4f63c5 346 SUPERFAMILY SSF101821 71 183 2.14E-31 T 28-03-2018 CO689_RS12160 7f1543711a196c0e7433f462b0b52c7c 173 SUPERFAMILY SSF52218 1 173 2.68E-41 T 28-03-2018 IPR029039 Flavoprotein-like domain CO689_RS12160 7f1543711a196c0e7433f462b0b52c7c 173 Gene3D G3DSA:3.40.50.360 1 173 1.1E-29 T 28-03-2018 IPR029039 Flavoprotein-like domain CO689_RS12160 7f1543711a196c0e7433f462b0b52c7c 173 Pfam PF02525 Flavodoxin-like fold 1 162 6.2E-38 T 28-03-2018 IPR003680 Flavodoxin-like fold CO689_RS09895 126d023e902c4a3196cc38813f2e5a3a 321 Gene3D G3DSA:3.40.50.720 115 288 4.2E-55 T 28-03-2018 CO689_RS09895 126d023e902c4a3196cc38813f2e5a3a 321 SUPERFAMILY SSF51735 101 288 3.3E-59 T 28-03-2018 IPR016040 NAD(P)-binding domain CO689_RS09895 126d023e902c4a3196cc38813f2e5a3a 321 SUPERFAMILY SSF52283 3 134 1.06E-36 T 28-03-2018 CO689_RS09895 126d023e902c4a3196cc38813f2e5a3a 321 Gene3D G3DSA:3.40.50.720 1 114 2.5E-36 T 28-03-2018 CO689_RS09895 126d023e902c4a3196cc38813f2e5a3a 321 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 4 318 2.4E-32 T 28-03-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 CO689_RS09895 126d023e902c4a3196cc38813f2e5a3a 321 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 109 287 5.0E-63 T 28-03-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 CO689_RS05250 ed58df7de3ef5fb6fdc11991d4fa34a1 86 Pfam PF09723 Zinc ribbon domain 1 40 1.3E-10 T 28-03-2018 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain CO689_RS05250 ed58df7de3ef5fb6fdc11991d4fa34a1 86 TIGRFAM TIGR02605 CxxC_CxxC_SSSS: putative regulatory protein, FmdB family 1 45 6.8E-12 T 28-03-2018 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain CO689_RS05250 ed58df7de3ef5fb6fdc11991d4fa34a1 86 SMART SM00834 1 41 4.4E-9 T 28-03-2018 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain CO689_RS12805 77f6c224ee93d224d084cf29a75ff819 332 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 134 154 4.2E-40 T 28-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 CO689_RS12805 77f6c224ee93d224d084cf29a75ff819 332 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 174 198 4.2E-40 T 28-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 CO689_RS12805 77f6c224ee93d224d084cf29a75ff819 332 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 56 83 4.2E-40 T 28-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 CO689_RS12805 77f6c224ee93d224d084cf29a75ff819 332 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 6 23 4.2E-40 T 28-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 CO689_RS12805 77f6c224ee93d224d084cf29a75ff819 332 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 239 256 4.2E-40 T 28-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 CO689_RS12805 77f6c224ee93d224d084cf29a75ff819 332 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 199 223 4.2E-40 T 28-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 CO689_RS12805 77f6c224ee93d224d084cf29a75ff819 332 Pfam PF07479 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus 181 320 6.5E-55 T 28-03-2018 IPR006109 Glycerol-3-phosphate dehydrogenase, NAD-dependent, C-terminal GO:0004367|GO:0005975|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 CO689_RS12805 77f6c224ee93d224d084cf29a75ff819 332 Hamap MF_00394 Glycerol-3-phosphate dehydrogenase [NAD(P)+] [gpsA]. 2 323 36.264 T 28-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 CO689_RS12805 77f6c224ee93d224d084cf29a75ff819 332 Pfam PF01210 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 3 160 4.8E-52 T 28-03-2018 IPR011128 Glycerol-3-phosphate dehydrogenase, NAD-dependent, N-terminal GO:0016616|GO:0046168|GO:0051287|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 CO689_RS12805 77f6c224ee93d224d084cf29a75ff819 332 Gene3D G3DSA:1.10.1040.10 181 331 3.0E-55 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CO689_RS12805 77f6c224ee93d224d084cf29a75ff819 332 ProSitePatterns PS00957 NAD-dependent glycerol-3-phosphate dehydrogenase signature. 189 210 - T 28-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 CO689_RS12805 77f6c224ee93d224d084cf29a75ff819 332 Gene3D G3DSA:3.40.50.720 1 180 1.8E-40 T 28-03-2018 CO689_RS12805 77f6c224ee93d224d084cf29a75ff819 332 SUPERFAMILY SSF51735 3 179 4.01E-53 T 28-03-2018 IPR016040 NAD(P)-binding domain CO689_RS12805 77f6c224ee93d224d084cf29a75ff819 332 PIRSF PIRSF000114 1 332 9.9E-112 T 28-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 CO689_RS12805 77f6c224ee93d224d084cf29a75ff819 332 SUPERFAMILY SSF48179 180 332 2.55E-58 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CO689_RS12365 f04428cd1700f25eb330346071dc400c 419 SUPERFAMILY SSF55729 309 408 2.01E-31 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CO689_RS12365 f04428cd1700f25eb330346071dc400c 419 SUPERFAMILY SSF55729 172 246 2.01E-31 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CO689_RS12365 f04428cd1700f25eb330346071dc400c 419 Gene3D G3DSA:3.40.630.30 170 388 1.4E-33 T 28-03-2018 CO689_RS12365 f04428cd1700f25eb330346071dc400c 419 Pfam PF02388 FemAB family 6 411 1.2E-138 T 28-03-2018 IPR003447 FemABX peptidyl transferase GO:0016755|GO:0044038 CO689_RS12365 f04428cd1700f25eb330346071dc400c 419 Gene3D G3DSA:3.40.630.30 1 169 6.9E-30 T 28-03-2018 CO689_RS12365 f04428cd1700f25eb330346071dc400c 419 SUPERFAMILY SSF55729 1 166 2.12E-47 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CO689_RS00215 3dccd057f3f958474df77ec4ac4f02f8 180 Gene3D G3DSA:1.20.1640.10 28 176 2.3E-4 T 28-03-2018 CO689_RS01080 33a53ff05b2688c1ddc01cc373379292 392 Pfam PF07690 Major Facilitator Superfamily 10 224 1.7E-21 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CO689_RS01080 33a53ff05b2688c1ddc01cc373379292 392 Pfam PF07690 Major Facilitator Superfamily 226 383 4.2E-19 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CO689_RS01080 33a53ff05b2688c1ddc01cc373379292 392 SUPERFAMILY SSF103473 5 386 8.37E-56 T 28-03-2018 IPR020846 Major facilitator superfamily domain CO689_RS01080 33a53ff05b2688c1ddc01cc373379292 392 Gene3D G3DSA:1.20.1250.20 195 388 1.5E-28 T 28-03-2018 CO689_RS01080 33a53ff05b2688c1ddc01cc373379292 392 Gene3D G3DSA:1.20.1250.20 4 184 3.0E-21 T 28-03-2018 CO689_RS08295 be1926acbba3daa1d373284753084cc4 307 ProSitePatterns PS00627 GHMP kinases putative ATP-binding domain. 93 104 - T 28-03-2018 IPR006203 GHMP kinase, ATP-binding, conserved site GO:0005524 CO689_RS08295 be1926acbba3daa1d373284753084cc4 307 Gene3D G3DSA:3.30.70.890 181 307 9.6E-32 T 28-03-2018 IPR013750 GHMP kinase, C-terminal domain CO689_RS08295 be1926acbba3daa1d373284753084cc4 307 SUPERFAMILY SSF54211 9 186 1.75E-33 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CO689_RS08295 be1926acbba3daa1d373284753084cc4 307 PRINTS PR00959 Mevalonate kinase family signature 9 33 8.7E-17 T 28-03-2018 CO689_RS08295 be1926acbba3daa1d373284753084cc4 307 PRINTS PR00959 Mevalonate kinase family signature 263 280 8.7E-17 T 28-03-2018 CO689_RS08295 be1926acbba3daa1d373284753084cc4 307 PRINTS PR00959 Mevalonate kinase family signature 91 113 8.7E-17 T 28-03-2018 CO689_RS08295 be1926acbba3daa1d373284753084cc4 307 SUPERFAMILY SSF55060 172 304 5.92E-31 T 28-03-2018 IPR013750 GHMP kinase, C-terminal domain CO689_RS08295 be1926acbba3daa1d373284753084cc4 307 TIGRFAM TIGR00549 mevalon_kin: mevalonate kinase 10 278 1.0E-78 T 28-03-2018 IPR006205 Mevalonate kinase GO:0004496|GO:0005524|GO:0005737|GO:0008299 KEGG: 00900+2.7.1.36|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-2426168 CO689_RS08295 be1926acbba3daa1d373284753084cc4 307 Gene3D G3DSA:3.30.230.10 56 180 9.7E-23 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CO689_RS08295 be1926acbba3daa1d373284753084cc4 307 Gene3D G3DSA:3.30.230.10 1 55 6.4E-5 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CO689_RS08295 be1926acbba3daa1d373284753084cc4 307 Pfam PF00288 GHMP kinases N terminal domain 87 150 2.6E-12 T 28-03-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 CO689_RS08295 be1926acbba3daa1d373284753084cc4 307 Pfam PF08544 GHMP kinases C terminal 218 297 1.0E-14 T 28-03-2018 IPR013750 GHMP kinase, C-terminal domain CO689_RS08225 a90cf62f89640561a82a968400ace83c 526 Gene3D G3DSA:3.40.50.880 34 354 3.8E-32 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CO689_RS08225 a90cf62f89640561a82a968400ace83c 526 Gene3D G3DSA:2.60.40.10 407 526 2.4E-4 T 28-03-2018 IPR013783 Immunoglobulin-like fold CO689_RS08225 a90cf62f89640561a82a968400ace83c 526 SUPERFAMILY SSF52317 39 156 4.03E-5 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CO689_RS08225 a90cf62f89640561a82a968400ace83c 526 SUPERFAMILY SSF52317 200 234 4.03E-5 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CO689_RS08225 a90cf62f89640561a82a968400ace83c 526 SUPERFAMILY SSF52317 269 298 4.03E-5 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CO689_RS03900 fdd6f3da7fa84201a0ff2030d53ae288 145 SMART SM00347 29 125 1.0E-18 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CO689_RS03900 fdd6f3da7fa84201a0ff2030d53ae288 145 PRINTS PR00598 Bacterial regulatory protein MarR family signature 53 69 2.2E-6 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CO689_RS03900 fdd6f3da7fa84201a0ff2030d53ae288 145 PRINTS PR00598 Bacterial regulatory protein MarR family signature 89 105 2.2E-6 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CO689_RS03900 fdd6f3da7fa84201a0ff2030d53ae288 145 PRINTS PR00598 Bacterial regulatory protein MarR family signature 70 85 2.2E-6 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CO689_RS03900 fdd6f3da7fa84201a0ff2030d53ae288 145 SUPERFAMILY SSF46785 7 140 1.44E-30 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS03900 fdd6f3da7fa84201a0ff2030d53ae288 145 Gene3D G3DSA:1.10.10.10 6 129 8.5E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS03900 fdd6f3da7fa84201a0ff2030d53ae288 145 Pfam PF01047 MarR family 36 93 3.8E-15 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CO689_RS07270 ae64b11b8f1124e3a0b85ab79d6de5a9 134 PRINTS PR00502 NUDIX hydrolase family signature 30 44 1.9E-7 T 28-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CO689_RS07270 ae64b11b8f1124e3a0b85ab79d6de5a9 134 PRINTS PR00502 NUDIX hydrolase family signature 44 59 1.9E-7 T 28-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CO689_RS07270 ae64b11b8f1124e3a0b85ab79d6de5a9 134 SUPERFAMILY SSF55811 3 124 4.2E-30 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CO689_RS07270 ae64b11b8f1124e3a0b85ab79d6de5a9 134 Gene3D G3DSA:3.90.79.10 1 129 1.2E-22 T 28-03-2018 CO689_RS07270 ae64b11b8f1124e3a0b85ab79d6de5a9 134 ProSitePatterns PS00893 Nudix box signature. 35 56 - T 28-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 CO689_RS07270 ae64b11b8f1124e3a0b85ab79d6de5a9 134 Pfam PF00293 NUDIX domain 5 108 2.1E-19 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 CO689_RS00875 59ac2c8c523379d0c1d19133788296d8 567 Gene3D G3DSA:1.20.120.570 25 204 0.039 T 28-03-2018 CO689_RS00875 59ac2c8c523379d0c1d19133788296d8 567 Pfam PF06160 Septation ring formation regulator, EzrA 5 560 2.5E-153 T 28-03-2018 IPR010379 Septation ring formation regulator EzrA GO:0000921|GO:0005940|GO:0016021 CO689_RS00875 59ac2c8c523379d0c1d19133788296d8 567 Gene3D G3DSA:1.20.1480.30 205 318 0.22 T 28-03-2018 CO689_RS00875 59ac2c8c523379d0c1d19133788296d8 567 Hamap MF_00728 Septation ring formation regulator EzrA [ezrA]. 3 564 20.362 T 28-03-2018 IPR010379 Septation ring formation regulator EzrA GO:0000921|GO:0005940|GO:0016021 CO689_RS00875 59ac2c8c523379d0c1d19133788296d8 567 Gene3D G3DSA:1.25.40.10 502 554 0.022 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CO689_RS09645 91aefd29a8a968f87fa9aed1b0b15f44 135 SUPERFAMILY SSF103084 1 134 3.66E-30 T 28-03-2018 IPR008822 Crossover junction endodeoxyribonuclease, RusA-like GO:0000287|GO:0006281|GO:0006310 CO689_RS09645 91aefd29a8a968f87fa9aed1b0b15f44 135 Pfam PF05866 Endodeoxyribonuclease RusA 14 132 4.6E-29 T 28-03-2018 IPR008822 Crossover junction endodeoxyribonuclease, RusA-like GO:0000287|GO:0006281|GO:0006310 CO689_RS09645 91aefd29a8a968f87fa9aed1b0b15f44 135 Gene3D G3DSA:3.30.1330.70 1 135 1.4E-20 T 28-03-2018 IPR008822 Crossover junction endodeoxyribonuclease, RusA-like GO:0000287|GO:0006281|GO:0006310 CO689_RS05325 636a3c1619fe356cb13bce585f9e7217 418 Pfam PF00534 Glycosyl transferases group 1 236 386 1.9E-28 T 28-03-2018 IPR001296 Glycosyl transferase, family 1 CO689_RS05325 636a3c1619fe356cb13bce585f9e7217 418 Gene3D G3DSA:3.40.50.2000 169 399 1.3E-32 T 28-03-2018 CO689_RS05325 636a3c1619fe356cb13bce585f9e7217 418 SUPERFAMILY SSF53756 6 62 5.5E-42 T 28-03-2018 CO689_RS05325 636a3c1619fe356cb13bce585f9e7217 418 SUPERFAMILY SSF53756 128 411 5.5E-42 T 28-03-2018 CO689_RS01210 b4d540f1fc3349c1e7545632d681442e 85 ProDom PD004225 UPF0161 ALPHA-HEMOLYSIN YIDD UNCHARACTERIZED CYTOSOLIC PRECURSOR SIGNAL YTJA RNPA SIMILAR 16 68 9.0E-22 T 28-03-2018 IPR002696 Putative membrane protein insertion efficiency factor CO689_RS01210 b4d540f1fc3349c1e7545632d681442e 85 TIGRFAM TIGR00278 TIGR00278: putative membrane protein insertion efficiency factor 5 76 6.8E-32 T 28-03-2018 IPR002696 Putative membrane protein insertion efficiency factor CO689_RS01210 b4d540f1fc3349c1e7545632d681442e 85 Pfam PF01809 Haemolytic domain 2 68 2.0E-30 T 28-03-2018 IPR002696 Putative membrane protein insertion efficiency factor CO689_RS01210 b4d540f1fc3349c1e7545632d681442e 85 SMART SM01234 1 68 8.0E-47 T 28-03-2018 IPR002696 Putative membrane protein insertion efficiency factor CO689_RS01210 b4d540f1fc3349c1e7545632d681442e 85 Hamap MF_00386 Putative membrane protein insertion efficiency factor [yidD]. 1 69 24.869 T 28-03-2018 IPR002696 Putative membrane protein insertion efficiency factor CO689_RS11295 bb666bc06875451baadb9a16627b0dda 160 TIGRFAM TIGR00077 lspA: signal peptidase II 12 159 2.4E-39 T 28-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 CO689_RS11295 bb666bc06875451baadb9a16627b0dda 160 Pfam PF01252 Signal peptidase (SPase) II 14 152 4.1E-37 T 28-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 CO689_RS11295 bb666bc06875451baadb9a16627b0dda 160 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 132 148 5.0E-18 T 28-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 CO689_RS11295 bb666bc06875451baadb9a16627b0dda 160 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 52 60 5.0E-18 T 28-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 CO689_RS11295 bb666bc06875451baadb9a16627b0dda 160 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 96 111 5.0E-18 T 28-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 CO689_RS11295 bb666bc06875451baadb9a16627b0dda 160 ProSitePatterns PS00855 Signal peptidases II signature. 99 111 - T 28-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 CO689_RS11295 bb666bc06875451baadb9a16627b0dda 160 Hamap MF_00161 Lipoprotein signal peptidase [lspA]. 5 157 17.37 T 28-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 CO689_RS12095 e3c6db9f38035af0e5fb8ad5e8419139 355 TIGRFAM TIGR00260 thrC: threonine synthase 8 326 1.2E-105 T 28-03-2018 IPR004450 Threonine synthase-like CO689_RS12095 e3c6db9f38035af0e5fb8ad5e8419139 355 Gene3D G3DSA:3.40.50.1100 147 336 1.7E-48 T 28-03-2018 CO689_RS12095 e3c6db9f38035af0e5fb8ad5e8419139 355 SUPERFAMILY SSF53686 5 352 9.3E-107 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CO689_RS12095 e3c6db9f38035af0e5fb8ad5e8419139 355 PIRSF PIRSF038945 1 351 1.3E-161 T 28-03-2018 IPR026260 Threonine synthase, bacterial/archaeal GO:0004795|GO:0009088 KEGG: 00260+4.2.3.1|KEGG: 00750+4.2.3.1 CO689_RS12095 e3c6db9f38035af0e5fb8ad5e8419139 355 Gene3D G3DSA:3.40.50.1100 39 146 2.2E-28 T 28-03-2018 CO689_RS12095 e3c6db9f38035af0e5fb8ad5e8419139 355 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 25 319 4.9E-77 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CO689_RS12095 e3c6db9f38035af0e5fb8ad5e8419139 355 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 52 65 - T 28-03-2018 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 CO689_RS12135 6a4825837f8a4a4c300902c9074437b2 311 Gene3D G3DSA:3.30.1450.10 98 166 0.062 T 28-03-2018 CO689_RS12135 6a4825837f8a4a4c300902c9074437b2 311 Gene3D G3DSA:3.40.33.10 180 311 7.2E-14 T 28-03-2018 IPR014044 CAP domain CO689_RS12135 6a4825837f8a4a4c300902c9074437b2 311 Pfam PF00188 Cysteine-rich secretory protein family 194 309 1.4E-12 T 28-03-2018 IPR014044 CAP domain CO689_RS12135 6a4825837f8a4a4c300902c9074437b2 311 Pfam PF14504 CAP-associated N-terminal 41 174 8.7E-40 T 28-03-2018 IPR029410 CAP-associated domain CO689_RS12135 6a4825837f8a4a4c300902c9074437b2 311 Gene3D G3DSA:3.30.1450.10 31 97 2.7E-9 T 28-03-2018 CO689_RS12135 6a4825837f8a4a4c300902c9074437b2 311 SUPERFAMILY SSF55797 186 309 4.19E-19 T 28-03-2018 IPR014044 CAP domain CO689_RS00850 329c586312facebdfe1a9a2389023457 315 PIRSF PIRSF026567 48 313 1.4E-101 T 28-03-2018 IPR016843 S-adenosyl-L-methionine dependent adenine methyltransferase, bacteria, predicted CO689_RS00850 329c586312facebdfe1a9a2389023457 315 PIRSF PIRSF026567 3 53 3.7E-4 T 28-03-2018 IPR016843 S-adenosyl-L-methionine dependent adenine methyltransferase, bacteria, predicted CO689_RS00850 329c586312facebdfe1a9a2389023457 315 Gene3D G3DSA:3.40.50.150 73 312 9.4E-25 T 28-03-2018 CO689_RS00850 329c586312facebdfe1a9a2389023457 315 SUPERFAMILY SSF53335 20 300 4.13E-33 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CO689_RS00850 329c586312facebdfe1a9a2389023457 315 Pfam PF02384 N-6 DNA Methylase 81 287 4.6E-7 T 28-03-2018 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 CO689_RS03360 f6b2318674ebe7f520eb318015ceef7a 251 Gene3D G3DSA:3.40.630.30 115 250 4.0E-12 T 28-03-2018 CO689_RS03360 f6b2318674ebe7f520eb318015ceef7a 251 Pfam PF13673 Acetyltransferase (GNAT) domain 149 239 4.8E-9 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CO689_RS03360 f6b2318674ebe7f520eb318015ceef7a 251 SUPERFAMILY SSF55729 115 242 1.62E-14 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CO689_RS08640 891e64384df792397c00fff0ba08809d 89 Pfam PF05800 Gas vesicle synthesis protein GvpO 4 83 1.9E-9 T 28-03-2018 IPR008634 Gas vesicle protein GvpO GO:0031412 CO689_RS08955 2295f3832704d4274ffda0ea89d5d097 354 Gene3D G3DSA:3.90.1150.10 250 351 2.9E-11 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CO689_RS08955 2295f3832704d4274ffda0ea89d5d097 354 Gene3D G3DSA:3.40.640.10 43 249 2.5E-44 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CO689_RS08955 2295f3832704d4274ffda0ea89d5d097 354 TIGRFAM TIGR01141 hisC: histidinol-phosphate transaminase 3 349 1.3E-92 T 28-03-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 CO689_RS08955 2295f3832704d4274ffda0ea89d5d097 354 SUPERFAMILY SSF53383 28 350 9.76E-73 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CO689_RS08955 2295f3832704d4274ffda0ea89d5d097 354 Hamap MF_01023 Histidinol-phosphate aminotransferase [hisC]. 1 351 55.703 T 28-03-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 CO689_RS08955 2295f3832704d4274ffda0ea89d5d097 354 Pfam PF00155 Aminotransferase class I and II 31 345 8.6E-53 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CO689_RS08955 2295f3832704d4274ffda0ea89d5d097 354 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 219 228 - T 28-03-2018 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0008152|GO:0016740 CO689_RS01220 5988a66e18eb517ba81677344771ce7e 462 TIGRFAM TIGR01923 menE: O-succinylbenzoate-CoA ligase 26 459 4.5E-162 T 28-03-2018 IPR010192 2-succinylbenzoate--CoA ligase GO:0005524|GO:0008756|GO:0009234 KEGG: 00130+6.2.1.26|MetaCyc: PWY-5837 CO689_RS01220 5988a66e18eb517ba81677344771ce7e 462 Hamap MF_00731 2-succinylbenzoate--CoA ligase [menE]. 1 462 39.557 T 28-03-2018 IPR010192 2-succinylbenzoate--CoA ligase GO:0005524|GO:0008756|GO:0009234 KEGG: 00130+6.2.1.26|MetaCyc: PWY-5837 CO689_RS01220 5988a66e18eb517ba81677344771ce7e 462 Gene3D G3DSA:3.30.300.30 367 462 1.6E-21 T 28-03-2018 CO689_RS01220 5988a66e18eb517ba81677344771ce7e 462 Gene3D G3DSA:3.40.50.980 143 287 1.2E-33 T 28-03-2018 CO689_RS01220 5988a66e18eb517ba81677344771ce7e 462 Pfam PF13193 AMP-binding enzyme C-terminal domain 381 454 1.4E-10 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CO689_RS01220 5988a66e18eb517ba81677344771ce7e 462 Gene3D G3DSA:2.30.38.10 288 365 1.5E-16 T 28-03-2018 CO689_RS01220 5988a66e18eb517ba81677344771ce7e 462 Gene3D G3DSA:3.40.50.980 2 142 1.3E-22 T 28-03-2018 CO689_RS01220 5988a66e18eb517ba81677344771ce7e 462 Pfam PF00501 AMP-binding enzyme 6 372 7.3E-72 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CO689_RS01220 5988a66e18eb517ba81677344771ce7e 462 SUPERFAMILY SSF56801 5 460 4.84E-106 T 28-03-2018 CO689_RS08950 8bfc4e412aeef3d145225b822dfa1043 504 SUPERFAMILY SSF53850 234 503 2.39E-73 T 28-03-2018 CO689_RS08950 8bfc4e412aeef3d145225b822dfa1043 504 SUPERFAMILY SSF161098 13 198 1.23E-40 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CO689_RS08950 8bfc4e412aeef3d145225b822dfa1043 504 Gene3D G3DSA:1.10.3720.10 2 209 7.2E-31 T 28-03-2018 CO689_RS08950 8bfc4e412aeef3d145225b822dfa1043 504 Pfam PF04069 Substrate binding domain of ABC-type glycine betaine transport system 234 499 4.8E-64 T 28-03-2018 IPR007210 ABC-type glycine betaine transport system, substrate-binding domain GO:0005215|GO:0006810 CO689_RS08950 8bfc4e412aeef3d145225b822dfa1043 504 Gene3D G3DSA:3.40.190.10 228 384 2.3E-34 T 28-03-2018 CO689_RS08950 8bfc4e412aeef3d145225b822dfa1043 504 Gene3D G3DSA:3.40.190.10 385 503 4.5E-24 T 28-03-2018 CO689_RS08950 8bfc4e412aeef3d145225b822dfa1043 504 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 37 209 1.5E-25 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CO689_RS10610 1bf4fd43ffefd7d860c68f36ad139b90 109 Gene3D G3DSA:1.20.58.80 5 103 4.5E-33 T 28-03-2018 IPR003188 Phosphotransferase system, lactose/cellobiose-type IIA subunit GO:0009401 CO689_RS10610 1bf4fd43ffefd7d860c68f36ad139b90 109 SUPERFAMILY SSF46973 4 102 7.59E-32 T 28-03-2018 IPR003188 Phosphotransferase system, lactose/cellobiose-type IIA subunit GO:0009401 CO689_RS10610 1bf4fd43ffefd7d860c68f36ad139b90 109 PIRSF PIRSF000699 1 109 3.7E-36 T 28-03-2018 IPR003188 Phosphotransferase system, lactose/cellobiose-type IIA subunit GO:0009401 CO689_RS10610 1bf4fd43ffefd7d860c68f36ad139b90 109 Pfam PF02255 PTS system, Lactose/Cellobiose specific IIA subunit 10 102 2.4E-31 T 28-03-2018 IPR003188 Phosphotransferase system, lactose/cellobiose-type IIA subunit GO:0009401 CO689_RS00915 8836b56005657033514208162fae43e2 530 SUPERFAMILY SSF143548 321 450 1.36E-28 T 28-03-2018 IPR029009 Allosteric substrate binding domain Reactome: R-HSA-977347 CO689_RS00915 8836b56005657033514208162fae43e2 530 SUPERFAMILY SSF52283 14 129 1.59E-38 T 28-03-2018 CO689_RS00915 8836b56005657033514208162fae43e2 530 Pfam PF01842 ACT domain 455 518 2.9E-10 T 28-03-2018 IPR002912 ACT domain CO689_RS00915 8836b56005657033514208162fae43e2 530 Gene3D G3DSA:3.30.1330.90 318 449 6.7E-30 T 28-03-2018 IPR029009 Allosteric substrate binding domain Reactome: R-HSA-977347 CO689_RS00915 8836b56005657033514208162fae43e2 530 Gene3D G3DSA:3.40.50.720 1 112 1.3E-36 T 28-03-2018 CO689_RS00915 8836b56005657033514208162fae43e2 530 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 107 281 1.9E-64 T 28-03-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 CO689_RS00915 8836b56005657033514208162fae43e2 530 SUPERFAMILY SSF55021 444 524 6.3E-20 T 28-03-2018 CO689_RS00915 8836b56005657033514208162fae43e2 530 SUPERFAMILY SSF51735 101 282 2.58E-59 T 28-03-2018 IPR016040 NAD(P)-binding domain CO689_RS00915 8836b56005657033514208162fae43e2 530 Gene3D G3DSA:3.40.50.720 113 284 2.1E-59 T 28-03-2018 CO689_RS00915 8836b56005657033514208162fae43e2 530 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 144 171 - T 28-03-2018 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 CO689_RS00915 8836b56005657033514208162fae43e2 530 TIGRFAM TIGR01327 PGDH: phosphoglycerate dehydrogenase 3 528 3.6E-212 T 28-03-2018 IPR006236 D-3-phosphoglycerate dehydrogenase GO:0004617|GO:0006564 KEGG: 00260+1.1.1.95|KEGG: 00680+1.1.1.95|Reactome: R-HSA-977347 CO689_RS00915 8836b56005657033514208162fae43e2 530 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 4 313 6.0E-37 T 28-03-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 CO689_RS00915 8836b56005657033514208162fae43e2 530 Gene3D G3DSA:3.30.70.260 450 526 7.5E-19 T 28-03-2018 CO689_RS10555 d0795210772ba0269a8ca79da009a0d9 139 SUPERFAMILY SSF46785 4 134 4.71E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS10555 d0795210772ba0269a8ca79da009a0d9 139 Gene3D G3DSA:1.10.10.10 1 106 5.7E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS10555 d0795210772ba0269a8ca79da009a0d9 139 Pfam PF01047 MarR family 29 87 2.6E-11 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CO689_RS10555 d0795210772ba0269a8ca79da009a0d9 139 PRINTS PR00598 Bacterial regulatory protein MarR family signature 82 98 3.9E-6 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CO689_RS10555 d0795210772ba0269a8ca79da009a0d9 139 PRINTS PR00598 Bacterial regulatory protein MarR family signature 63 78 3.9E-6 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CO689_RS10555 d0795210772ba0269a8ca79da009a0d9 139 PRINTS PR00598 Bacterial regulatory protein MarR family signature 46 62 3.9E-6 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CO689_RS10555 d0795210772ba0269a8ca79da009a0d9 139 PRINTS PR00598 Bacterial regulatory protein MarR family signature 112 132 3.9E-6 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CO689_RS10555 d0795210772ba0269a8ca79da009a0d9 139 SMART SM00347 22 122 7.0E-21 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CO689_RS10555 d0795210772ba0269a8ca79da009a0d9 139 Gene3D G3DSA:1.10.287.100 107 133 0.0015 T 28-03-2018 CO689_RS07975 d0e57db2d8a90de51d24e143e0c897b0 213 Gene3D G3DSA:1.10.3130.10 1 56 5.5E-21 T 28-03-2018 CO689_RS07975 d0e57db2d8a90de51d24e143e0c897b0 213 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 71 108 1.2E-6 T 28-03-2018 IPR001451 Hexapeptide repeat CO689_RS07975 d0e57db2d8a90de51d24e143e0c897b0 213 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 120 150 6.3E-8 T 28-03-2018 IPR001451 Hexapeptide repeat CO689_RS07975 d0e57db2d8a90de51d24e143e0c897b0 213 SUPERFAMILY SSF51161 3 171 1.34E-52 T 28-03-2018 IPR011004 Trimeric LpxA-like CO689_RS07975 d0e57db2d8a90de51d24e143e0c897b0 213 Gene3D G3DSA:2.160.10.10 57 213 1.8E-39 T 28-03-2018 CO689_RS07975 d0e57db2d8a90de51d24e143e0c897b0 213 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 126 154 - T 28-03-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 CO689_RS07975 d0e57db2d8a90de51d24e143e0c897b0 213 TIGRFAM TIGR01172 cysE: serine O-acetyltransferase 6 165 3.1E-74 T 28-03-2018 IPR005881 Serine O-acetyltransferase GO:0005737|GO:0006535|GO:0009001 KEGG: 00270+2.3.1.30|KEGG: 00920+2.3.1.30|MetaCyc: PWY-6936|MetaCyc: PWY-7274 CO689_RS07975 d0e57db2d8a90de51d24e143e0c897b0 213 PIRSF PIRSF000441 1 210 3.7E-82 T 28-03-2018 IPR005881 Serine O-acetyltransferase GO:0005737|GO:0006535|GO:0009001 KEGG: 00270+2.3.1.30|KEGG: 00920+2.3.1.30|MetaCyc: PWY-6936|MetaCyc: PWY-7274 CO689_RS12460 3a146c068d7583cefa96fb72ec3a7ecc 241 PIRSF PIRSF000161 1 241 2.5E-70 T 28-03-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CO689_RS12460 3a146c068d7583cefa96fb72ec3a7ecc 241 Gene3D G3DSA:3.30.360.10 122 210 2.2E-31 T 28-03-2018 CO689_RS12460 3a146c068d7583cefa96fb72ec3a7ecc 241 ProSitePatterns PS01298 Dihydrodipicolinate reductase signature. 130 147 - T 28-03-2018 IPR022664 Dihydrodipicolinate reductase, conserved site GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CO689_RS12460 3a146c068d7583cefa96fb72ec3a7ecc 241 Pfam PF05173 Dihydrodipicolinate reductase, C-terminus 109 238 5.3E-39 T 28-03-2018 IPR022663 Dihydrodipicolinate reductase, C-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CO689_RS12460 3a146c068d7583cefa96fb72ec3a7ecc 241 TIGRFAM TIGR00036 dapB: 4-hydroxy-tetrahydrodipicolinate reductase 48 239 3.5E-51 T 28-03-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CO689_RS12460 3a146c068d7583cefa96fb72ec3a7ecc 241 Hamap MF_00102 4-hydroxy-tetrahydrodipicolinate reductase [dapB]. 1 241 26.744 T 28-03-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CO689_RS12460 3a146c068d7583cefa96fb72ec3a7ecc 241 SUPERFAMILY SSF55347 109 212 1.83E-28 T 28-03-2018 CO689_RS12460 3a146c068d7583cefa96fb72ec3a7ecc 241 Pfam PF01113 Dihydrodipicolinate reductase, N-terminus 1 106 3.8E-14 T 28-03-2018 IPR000846 Dihydrodipicolinate reductase, N-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CO689_RS12460 3a146c068d7583cefa96fb72ec3a7ecc 241 SUPERFAMILY SSF51735 1 105 1.79E-20 T 28-03-2018 IPR016040 NAD(P)-binding domain CO689_RS12460 3a146c068d7583cefa96fb72ec3a7ecc 241 SUPERFAMILY SSF51735 211 239 1.79E-20 T 28-03-2018 IPR016040 NAD(P)-binding domain CO689_RS12460 3a146c068d7583cefa96fb72ec3a7ecc 241 Gene3D G3DSA:3.40.50.720 1 121 3.3E-20 T 28-03-2018 CO689_RS06900 784d6cf5a6182f69b56dffd68008a40d 159 TIGRFAM TIGR00246 tRNA_RlmH_YbeA: rRNA large subunit m3Psi methyltransferase RlmH 2 159 5.8E-54 T 28-03-2018 IPR003742 RNA methyltransferase RlmH GO:0005737|GO:0006364|GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CO689_RS06900 784d6cf5a6182f69b56dffd68008a40d 159 SUPERFAMILY SSF75217 1 157 4.08E-56 T 28-03-2018 IPR029028 Alpha/beta knot methyltransferases CO689_RS06900 784d6cf5a6182f69b56dffd68008a40d 159 PIRSF PIRSF004505 1 159 1.3E-52 T 28-03-2018 IPR003742 RNA methyltransferase RlmH GO:0005737|GO:0006364|GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CO689_RS06900 784d6cf5a6182f69b56dffd68008a40d 159 Gene3D G3DSA:3.40.1280.10 1 159 5.2E-62 T 28-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal CO689_RS06900 784d6cf5a6182f69b56dffd68008a40d 159 Hamap MF_00658 Ribosomal RNA large subunit methyltransferase H [rlmH]. 1 159 29.91 T 28-03-2018 IPR003742 RNA methyltransferase RlmH GO:0005737|GO:0006364|GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CO689_RS06900 784d6cf5a6182f69b56dffd68008a40d 159 Pfam PF02590 Predicted SPOUT methyltransferase 1 158 1.0E-59 T 28-03-2018 IPR003742 RNA methyltransferase RlmH GO:0005737|GO:0006364|GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CO689_RS05725 4edae52c3e9e40283eec6306bc6748d6 150 TIGRFAM TIGR04011 poly_gGlu_PgsC: poly-gamma-glutamate biosynthesis protein PgsC 11 140 1.1E-41 T 28-03-2018 IPR008338 Capsule biosynthesis protein CapC GO:0016020|GO:0045227 CO689_RS05725 4edae52c3e9e40283eec6306bc6748d6 150 Pfam PF14102 Capsule biosynthesis CapC 12 129 1.7E-38 T 28-03-2018 IPR008338 Capsule biosynthesis protein CapC GO:0016020|GO:0045227 CO689_RS05725 4edae52c3e9e40283eec6306bc6748d6 150 PRINTS PR01759 Capsule biosynthesis protein CapC signature 20 37 2.0E-33 T 28-03-2018 IPR008338 Capsule biosynthesis protein CapC GO:0016020|GO:0045227 CO689_RS05725 4edae52c3e9e40283eec6306bc6748d6 150 PRINTS PR01759 Capsule biosynthesis protein CapC signature 66 80 2.0E-33 T 28-03-2018 IPR008338 Capsule biosynthesis protein CapC GO:0016020|GO:0045227 CO689_RS05725 4edae52c3e9e40283eec6306bc6748d6 150 PRINTS PR01759 Capsule biosynthesis protein CapC signature 118 132 2.0E-33 T 28-03-2018 IPR008338 Capsule biosynthesis protein CapC GO:0016020|GO:0045227 CO689_RS05725 4edae52c3e9e40283eec6306bc6748d6 150 PRINTS PR01759 Capsule biosynthesis protein CapC signature 2 17 2.0E-33 T 28-03-2018 IPR008338 Capsule biosynthesis protein CapC GO:0016020|GO:0045227 CO689_RS05725 4edae52c3e9e40283eec6306bc6748d6 150 PRINTS PR01759 Capsule biosynthesis protein CapC signature 88 101 2.0E-33 T 28-03-2018 IPR008338 Capsule biosynthesis protein CapC GO:0016020|GO:0045227 CO689_RS04170 74d6d036a48d1bdcdf19cb6732938647 460 SUPERFAMILY SSF53474 4 457 8.62E-86 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CO689_RS04170 74d6d036a48d1bdcdf19cb6732938647 460 ProSitePatterns PS00122 Carboxylesterases type-B serine active site. 188 203 - T 28-03-2018 IPR019826 Carboxylesterase type B, active site CO689_RS04170 74d6d036a48d1bdcdf19cb6732938647 460 Gene3D G3DSA:3.40.50.1820 2 457 5.1E-83 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CO689_RS04170 74d6d036a48d1bdcdf19cb6732938647 460 Pfam PF00135 Carboxylesterase family 8 444 2.3E-79 T 28-03-2018 IPR002018 Carboxylesterase, type B CO689_RS04710 473187d0e55866e644cf8f15c3010f5a 280 Pfam PF00106 short chain dehydrogenase 11 217 2.3E-47 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CO689_RS04710 473187d0e55866e644cf8f15c3010f5a 280 Gene3D G3DSA:3.40.50.720 4 278 1.3E-58 T 28-03-2018 CO689_RS04710 473187d0e55866e644cf8f15c3010f5a 280 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 156 164 3.9E-9 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CO689_RS04710 473187d0e55866e644cf8f15c3010f5a 280 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 176 195 3.9E-9 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CO689_RS04710 473187d0e55866e644cf8f15c3010f5a 280 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 86 97 3.9E-9 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CO689_RS04710 473187d0e55866e644cf8f15c3010f5a 280 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 163 191 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CO689_RS04710 473187d0e55866e644cf8f15c3010f5a 280 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 197 214 6.4E-31 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CO689_RS04710 473187d0e55866e644cf8f15c3010f5a 280 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 176 195 6.4E-31 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CO689_RS04710 473187d0e55866e644cf8f15c3010f5a 280 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 86 97 6.4E-31 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CO689_RS04710 473187d0e55866e644cf8f15c3010f5a 280 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 150 166 6.4E-31 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CO689_RS04710 473187d0e55866e644cf8f15c3010f5a 280 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 237 257 6.4E-31 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CO689_RS04710 473187d0e55866e644cf8f15c3010f5a 280 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 12 29 6.4E-31 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CO689_RS04710 473187d0e55866e644cf8f15c3010f5a 280 SUPERFAMILY SSF51735 9 276 5.75E-65 T 28-03-2018 IPR016040 NAD(P)-binding domain CO689_RS11860 26e5caf721a84f3832c8b30b55c6ca7d 354 SMART SM00382 57 228 1.4E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain CO689_RS11860 26e5caf721a84f3832c8b30b55c6ca7d 354 TIGRFAM TIGR02012 tigrfam_recA: protein RecA 4 324 1.4E-171 T 28-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 CO689_RS11860 26e5caf721a84f3832c8b30b55c6ca7d 354 SUPERFAMILY SSF52540 3 267 1.34E-65 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CO689_RS11860 26e5caf721a84f3832c8b30b55c6ca7d 354 ProSitePatterns PS00321 recA signature. 213 221 - T 28-03-2018 IPR020584 DNA recombination/repair protein RecA, conserved site GO:0003677|GO:0005524|GO:0006259|GO:0008094 CO689_RS11860 26e5caf721a84f3832c8b30b55c6ca7d 354 SUPERFAMILY SSF54752 268 326 2.22E-22 T 28-03-2018 IPR023400 DNA recombination and repair protein RecA, C-terminal CO689_RS11860 26e5caf721a84f3832c8b30b55c6ca7d 354 Gene3D G3DSA:3.40.50.300 26 268 1.0E-46 T 28-03-2018 CO689_RS11860 26e5caf721a84f3832c8b30b55c6ca7d 354 Gene3D G3DSA:3.30.250.10 269 326 1.5E-26 T 28-03-2018 IPR023400 DNA recombination and repair protein RecA, C-terminal CO689_RS11860 26e5caf721a84f3832c8b30b55c6ca7d 354 Hamap MF_00268 Protein RecA [recA]. 5 329 52.9 T 28-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 CO689_RS11860 26e5caf721a84f3832c8b30b55c6ca7d 354 PRINTS PR00142 RecA protein signature 297 314 6.5E-85 T 28-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 CO689_RS11860 26e5caf721a84f3832c8b30b55c6ca7d 354 PRINTS PR00142 RecA protein signature 127 156 6.5E-85 T 28-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 CO689_RS11860 26e5caf721a84f3832c8b30b55c6ca7d 354 PRINTS PR00142 RecA protein signature 243 272 6.5E-85 T 28-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 CO689_RS11860 26e5caf721a84f3832c8b30b55c6ca7d 354 PRINTS PR00142 RecA protein signature 93 122 6.5E-85 T 28-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 CO689_RS11860 26e5caf721a84f3832c8b30b55c6ca7d 354 PRINTS PR00142 RecA protein signature 165 194 6.5E-85 T 28-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 CO689_RS11860 26e5caf721a84f3832c8b30b55c6ca7d 354 PRINTS PR00142 RecA protein signature 210 238 6.5E-85 T 28-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 CO689_RS11860 26e5caf721a84f3832c8b30b55c6ca7d 354 Pfam PF00154 recA bacterial DNA recombination protein 7 268 1.1E-143 T 28-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 CO689_RS09100 1b6100ab7bc02a6f24274e5c0d847fdd 187 SUPERFAMILY SSF69754 4 106 1.31E-30 T 28-03-2018 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 CO689_RS09100 1b6100ab7bc02a6f24274e5c0d847fdd 187 Pfam PF16321 Sigma 54 modulation/S30EA ribosomal protein C terminus 126 181 1.7E-27 T 28-03-2018 IPR032528 Sigma 54 modulation/S30EA ribosomal protein, C-terminal CO689_RS09100 1b6100ab7bc02a6f24274e5c0d847fdd 187 Pfam PF02482 Sigma 54 modulation protein / S30EA ribosomal protein 5 96 4.2E-27 T 28-03-2018 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 CO689_RS09100 1b6100ab7bc02a6f24274e5c0d847fdd 187 Hamap MF_00839 Ribosome hibernation promoting factor [hpf]. 2 185 25.041 T 28-03-2018 IPR034694 Ribosome hibernation promoting factor, long/plastid CO689_RS09100 1b6100ab7bc02a6f24274e5c0d847fdd 187 TIGRFAM TIGR00741 yfiA: ribosomal subunit interface protein 4 102 5.0E-31 T 28-03-2018 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 CO689_RS09100 1b6100ab7bc02a6f24274e5c0d847fdd 187 Gene3D G3DSA:3.30.160.100 2 100 1.7E-28 T 28-03-2018 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 CO689_RS04175 aa8275188e51770b2dea33c1f7a0b1f4 387 Pfam PF07690 Major Facilitator Superfamily 10 323 2.0E-37 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CO689_RS04175 aa8275188e51770b2dea33c1f7a0b1f4 387 Gene3D G3DSA:1.20.1250.20 195 385 1.5E-18 T 28-03-2018 CO689_RS04175 aa8275188e51770b2dea33c1f7a0b1f4 387 Gene3D G3DSA:1.20.1250.20 2 194 1.2E-24 T 28-03-2018 CO689_RS04175 aa8275188e51770b2dea33c1f7a0b1f4 387 SUPERFAMILY SSF103473 6 380 3.66E-55 T 28-03-2018 IPR020846 Major facilitator superfamily domain CO689_RS06715 3bb63fb5c058706237ca2a82a7de1b09 673 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 77 671 1.7E-182 T 28-03-2018 CO689_RS06715 3bb63fb5c058706237ca2a82a7de1b09 673 Pfam PF00122 E1-E2 ATPase 168 342 1.4E-48 T 28-03-2018 CO689_RS06715 3bb63fb5c058706237ca2a82a7de1b09 673 SUPERFAMILY SSF81665 111 167 3.01E-12 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CO689_RS06715 3bb63fb5c058706237ca2a82a7de1b09 673 SUPERFAMILY SSF81665 265 356 3.01E-12 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CO689_RS06715 3bb63fb5c058706237ca2a82a7de1b09 673 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 136 647 4.6E-85 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CO689_RS06715 3bb63fb5c058706237ca2a82a7de1b09 673 Gene3D G3DSA:3.40.50.1000 487 627 7.4E-37 T 28-03-2018 IPR023214 HAD-like domain CO689_RS06715 3bb63fb5c058706237ca2a82a7de1b09 673 Gene3D G3DSA:1.20.1110.10 126 380 1.3E-31 T 28-03-2018 CO689_RS06715 3bb63fb5c058706237ca2a82a7de1b09 673 Pfam PF00702 haloacid dehalogenase-like hydrolase 360 576 1.4E-34 T 28-03-2018 CO689_RS06715 3bb63fb5c058706237ca2a82a7de1b09 673 SUPERFAMILY SSF56784 422 667 6.6E-50 T 28-03-2018 IPR023214 HAD-like domain CO689_RS06715 3bb63fb5c058706237ca2a82a7de1b09 673 SUPERFAMILY SSF56784 363 382 6.6E-50 T 28-03-2018 IPR023214 HAD-like domain CO689_RS06715 3bb63fb5c058706237ca2a82a7de1b09 673 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 366 372 - T 28-03-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 CO689_RS06715 3bb63fb5c058706237ca2a82a7de1b09 673 SUPERFAMILY SSF81653 169 264 5.62E-23 T 28-03-2018 IPR008250 P-type ATPase, A domain Reactome: R-HSA-936837 CO689_RS06715 3bb63fb5c058706237ca2a82a7de1b09 673 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 509 519 3.2E-24 T 28-03-2018 CO689_RS06715 3bb63fb5c058706237ca2a82a7de1b09 673 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 214 228 3.2E-24 T 28-03-2018 CO689_RS06715 3bb63fb5c058706237ca2a82a7de1b09 673 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 364 378 3.2E-24 T 28-03-2018 CO689_RS06715 3bb63fb5c058706237ca2a82a7de1b09 673 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 562 581 3.2E-24 T 28-03-2018 CO689_RS06715 3bb63fb5c058706237ca2a82a7de1b09 673 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 585 597 3.2E-24 T 28-03-2018 CO689_RS06715 3bb63fb5c058706237ca2a82a7de1b09 673 Gene3D G3DSA:3.40.1110.10 381 486 7.8E-21 T 28-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 CO689_RS06715 3bb63fb5c058706237ca2a82a7de1b09 673 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 593 618 6.6E-10 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CO689_RS06715 3bb63fb5c058706237ca2a82a7de1b09 673 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 562 578 6.6E-10 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CO689_RS06715 3bb63fb5c058706237ca2a82a7de1b09 673 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 534 550 6.6E-10 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CO689_RS06715 3bb63fb5c058706237ca2a82a7de1b09 673 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 95 669 4.5E-174 T 28-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 CO689_RS00090 f7b22970e08c9a2a73b96eea1b66df4f 444 Pfam PF05598 Transposase domain (DUF772) 52 127 3.1E-21 T 28-03-2018 IPR008490 Transposase InsH, N-terminal CO689_RS00090 f7b22970e08c9a2a73b96eea1b66df4f 444 Pfam PF13751 Transposase DDE domain 321 439 1.9E-22 T 28-03-2018 IPR025668 Transposase DDE domain CO689_RS12320 f7b22970e08c9a2a73b96eea1b66df4f 444 Pfam PF05598 Transposase domain (DUF772) 52 127 3.1E-21 T 28-03-2018 IPR008490 Transposase InsH, N-terminal CO689_RS12320 f7b22970e08c9a2a73b96eea1b66df4f 444 Pfam PF13751 Transposase DDE domain 321 439 1.9E-22 T 28-03-2018 IPR025668 Transposase DDE domain CO689_RS06825 f7b22970e08c9a2a73b96eea1b66df4f 444 Pfam PF05598 Transposase domain (DUF772) 52 127 3.1E-21 T 28-03-2018 IPR008490 Transposase InsH, N-terminal CO689_RS06825 f7b22970e08c9a2a73b96eea1b66df4f 444 Pfam PF13751 Transposase DDE domain 321 439 1.9E-22 T 28-03-2018 IPR025668 Transposase DDE domain CO689_RS11915 f7b22970e08c9a2a73b96eea1b66df4f 444 Pfam PF05598 Transposase domain (DUF772) 52 127 3.1E-21 T 28-03-2018 IPR008490 Transposase InsH, N-terminal CO689_RS11915 f7b22970e08c9a2a73b96eea1b66df4f 444 Pfam PF13751 Transposase DDE domain 321 439 1.9E-22 T 28-03-2018 IPR025668 Transposase DDE domain CO689_RS00425 f7b22970e08c9a2a73b96eea1b66df4f 444 Pfam PF05598 Transposase domain (DUF772) 52 127 3.1E-21 T 28-03-2018 IPR008490 Transposase InsH, N-terminal CO689_RS00425 f7b22970e08c9a2a73b96eea1b66df4f 444 Pfam PF13751 Transposase DDE domain 321 439 1.9E-22 T 28-03-2018 IPR025668 Transposase DDE domain CO689_RS05820 f7b22970e08c9a2a73b96eea1b66df4f 444 Pfam PF05598 Transposase domain (DUF772) 52 127 3.1E-21 T 28-03-2018 IPR008490 Transposase InsH, N-terminal CO689_RS05820 f7b22970e08c9a2a73b96eea1b66df4f 444 Pfam PF13751 Transposase DDE domain 321 439 1.9E-22 T 28-03-2018 IPR025668 Transposase DDE domain CO689_RS03185 f7b22970e08c9a2a73b96eea1b66df4f 444 Pfam PF05598 Transposase domain (DUF772) 52 127 3.1E-21 T 28-03-2018 IPR008490 Transposase InsH, N-terminal CO689_RS03185 f7b22970e08c9a2a73b96eea1b66df4f 444 Pfam PF13751 Transposase DDE domain 321 439 1.9E-22 T 28-03-2018 IPR025668 Transposase DDE domain CO689_RS00735 f7b22970e08c9a2a73b96eea1b66df4f 444 Pfam PF05598 Transposase domain (DUF772) 52 127 3.1E-21 T 28-03-2018 IPR008490 Transposase InsH, N-terminal CO689_RS00735 f7b22970e08c9a2a73b96eea1b66df4f 444 Pfam PF13751 Transposase DDE domain 321 439 1.9E-22 T 28-03-2018 IPR025668 Transposase DDE domain CO689_RS00560 f7b22970e08c9a2a73b96eea1b66df4f 444 Pfam PF05598 Transposase domain (DUF772) 52 127 3.1E-21 T 28-03-2018 IPR008490 Transposase InsH, N-terminal CO689_RS00560 f7b22970e08c9a2a73b96eea1b66df4f 444 Pfam PF13751 Transposase DDE domain 321 439 1.9E-22 T 28-03-2018 IPR025668 Transposase DDE domain CO689_RS09780 f7b22970e08c9a2a73b96eea1b66df4f 444 Pfam PF05598 Transposase domain (DUF772) 52 127 3.1E-21 T 28-03-2018 IPR008490 Transposase InsH, N-terminal CO689_RS09780 f7b22970e08c9a2a73b96eea1b66df4f 444 Pfam PF13751 Transposase DDE domain 321 439 1.9E-22 T 28-03-2018 IPR025668 Transposase DDE domain CO689_RS02800 388d145780bf0d6ee3bc0656182b9710 445 Gene3D G3DSA:1.20.1250.20 253 445 5.9E-20 T 28-03-2018 CO689_RS02800 388d145780bf0d6ee3bc0656182b9710 445 PRINTS PR01036 Tetracycline resistance protein TetB signature 11 35 3.3E-11 T 28-03-2018 CO689_RS02800 388d145780bf0d6ee3bc0656182b9710 445 PRINTS PR01036 Tetracycline resistance protein TetB signature 131 155 3.3E-11 T 28-03-2018 CO689_RS02800 388d145780bf0d6ee3bc0656182b9710 445 PRINTS PR01036 Tetracycline resistance protein TetB signature 388 407 3.3E-11 T 28-03-2018 CO689_RS02800 388d145780bf0d6ee3bc0656182b9710 445 PRINTS PR01036 Tetracycline resistance protein TetB signature 101 121 3.3E-11 T 28-03-2018 CO689_RS02800 388d145780bf0d6ee3bc0656182b9710 445 SUPERFAMILY SSF103473 9 196 5.89E-48 T 28-03-2018 IPR020846 Major facilitator superfamily domain CO689_RS02800 388d145780bf0d6ee3bc0656182b9710 445 SUPERFAMILY SSF103473 240 442 5.89E-48 T 28-03-2018 IPR020846 Major facilitator superfamily domain CO689_RS02800 388d145780bf0d6ee3bc0656182b9710 445 Pfam PF07690 Major Facilitator Superfamily 12 397 6.0E-44 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CO689_RS02800 388d145780bf0d6ee3bc0656182b9710 445 Gene3D G3DSA:1.20.1250.20 4 186 7.7E-26 T 28-03-2018 CO689_RS12205 1ca4bdaf03fc68d9087b2c5af3558ab4 1012 Pfam PF13558 Putative exonuclease SbcCD, C subunit 899 969 1.1E-12 T 28-03-2018 CO689_RS12205 1ca4bdaf03fc68d9087b2c5af3558ab4 1012 SUPERFAMILY SSF75712 475 569 1.57E-7 T 28-03-2018 CO689_RS12205 1ca4bdaf03fc68d9087b2c5af3558ab4 1012 Gene3D G3DSA:1.10.287.510 437 583 2.2E-4 T 28-03-2018 CO689_RS12205 1ca4bdaf03fc68d9087b2c5af3558ab4 1012 Gene3D G3DSA:1.10.287.510 319 436 7.6E-5 T 28-03-2018 CO689_RS12205 1ca4bdaf03fc68d9087b2c5af3558ab4 1012 Pfam PF13476 AAA domain 6 292 3.8E-11 T 28-03-2018 CO689_RS12205 1ca4bdaf03fc68d9087b2c5af3558ab4 1012 Gene3D G3DSA:3.40.50.300 718 1008 8.8E-17 T 28-03-2018 CO689_RS12205 1ca4bdaf03fc68d9087b2c5af3558ab4 1012 Gene3D G3DSA:1.20.5.50 617 717 0.0011 T 28-03-2018 CO689_RS12205 1ca4bdaf03fc68d9087b2c5af3558ab4 1012 Gene3D G3DSA:3.40.50.300 1 190 4.2E-24 T 28-03-2018 CO689_RS12205 1ca4bdaf03fc68d9087b2c5af3558ab4 1012 SUPERFAMILY SSF52540 904 998 9.88E-22 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CO689_RS12205 1ca4bdaf03fc68d9087b2c5af3558ab4 1012 SUPERFAMILY SSF52540 6 223 9.88E-22 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CO689_RS10150 c4f2a885a3d0724bd06decd4efb7d2d2 313 Hamap MF_01815 3-oxoacyl-[acyl-carrier-protein] synthase 3 [fabH]. 1 311 68.183 T 28-03-2018 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 CO689_RS10150 c4f2a885a3d0724bd06decd4efb7d2d2 313 Gene3D G3DSA:3.40.47.10 1 160 6.8E-41 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CO689_RS10150 c4f2a885a3d0724bd06decd4efb7d2d2 313 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 223 311 1.8E-35 T 28-03-2018 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 CO689_RS10150 c4f2a885a3d0724bd06decd4efb7d2d2 313 TIGRFAM TIGR00747 fabH: 3-oxoacyl-[acyl-carrier-protein] synthase III 1 311 1.0E-122 T 28-03-2018 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 CO689_RS10150 c4f2a885a3d0724bd06decd4efb7d2d2 313 Gene3D G3DSA:3.40.47.10 161 311 8.3E-42 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CO689_RS10150 c4f2a885a3d0724bd06decd4efb7d2d2 313 SUPERFAMILY SSF53901 3 311 1.56E-75 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CO689_RS10150 c4f2a885a3d0724bd06decd4efb7d2d2 313 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 107 184 8.3E-28 T 28-03-2018 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 CO689_RS09305 0dc7cd80c87038464502df6bba1b2bb8 300 SUPERFAMILY SSF51735 1 298 7.27E-34 T 28-03-2018 IPR016040 NAD(P)-binding domain CO689_RS09305 0dc7cd80c87038464502df6bba1b2bb8 300 Gene3D G3DSA:3.40.50.720 2 300 4.2E-27 T 28-03-2018 CO689_RS09305 0dc7cd80c87038464502df6bba1b2bb8 300 TIGRFAM TIGR01777 yfcH: TIGR01777 family protein 5 294 4.0E-99 T 28-03-2018 IPR010099 Epimerase family protein SDR39U1 CO689_RS09305 0dc7cd80c87038464502df6bba1b2bb8 300 Pfam PF01370 NAD dependent epimerase/dehydratase family 5 223 1.3E-17 T 28-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 CO689_RS09305 0dc7cd80c87038464502df6bba1b2bb8 300 Pfam PF08338 Domain of unknown function (DUF1731) 251 296 5.4E-16 T 28-03-2018 IPR013549 Domain of unknown function DUF1731 CO689_RS10385 8a6e9de3f43a92c026b9847dc440f80d 417 Hamap MF_01024 Histidinol dehydrogenase [hisD]. 1 412 39.084 T 28-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CO689_RS10385 8a6e9de3f43a92c026b9847dc440f80d 417 Gene3D G3DSA:3.40.50.1980 18 210 1.7E-80 T 28-03-2018 CO689_RS10385 8a6e9de3f43a92c026b9847dc440f80d 417 Pfam PF00815 Histidinol dehydrogenase 19 412 3.1E-150 T 28-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CO689_RS10385 8a6e9de3f43a92c026b9847dc440f80d 417 PIRSF PIRSF000099 2 415 1.3E-154 T 28-03-2018 IPR022695 Histidinol dehydrogenase, monofunctional GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CO689_RS10385 8a6e9de3f43a92c026b9847dc440f80d 417 SUPERFAMILY SSF53720 19 412 1.63E-70 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CO689_RS10385 8a6e9de3f43a92c026b9847dc440f80d 417 TIGRFAM TIGR00069 hisD: histidinol dehydrogenase 25 411 5.0E-151 T 28-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CO689_RS10385 8a6e9de3f43a92c026b9847dc440f80d 417 Gene3D G3DSA:3.40.50.1980 211 356 1.7E-57 T 28-03-2018 CO689_RS10385 8a6e9de3f43a92c026b9847dc440f80d 417 PRINTS PR00083 Histidinol dehydrogenase signature 25 49 7.8E-82 T 28-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CO689_RS10385 8a6e9de3f43a92c026b9847dc440f80d 417 PRINTS PR00083 Histidinol dehydrogenase signature 155 181 7.8E-82 T 28-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CO689_RS10385 8a6e9de3f43a92c026b9847dc440f80d 417 PRINTS PR00083 Histidinol dehydrogenase signature 214 235 7.8E-82 T 28-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CO689_RS10385 8a6e9de3f43a92c026b9847dc440f80d 417 PRINTS PR00083 Histidinol dehydrogenase signature 121 147 7.8E-82 T 28-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CO689_RS10385 8a6e9de3f43a92c026b9847dc440f80d 417 PRINTS PR00083 Histidinol dehydrogenase signature 346 364 7.8E-82 T 28-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CO689_RS10385 8a6e9de3f43a92c026b9847dc440f80d 417 PRINTS PR00083 Histidinol dehydrogenase signature 305 330 7.8E-82 T 28-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CO689_RS10385 8a6e9de3f43a92c026b9847dc440f80d 417 PRINTS PR00083 Histidinol dehydrogenase signature 185 210 7.8E-82 T 28-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CO689_RS10385 8a6e9de3f43a92c026b9847dc440f80d 417 PRINTS PR00083 Histidinol dehydrogenase signature 236 255 7.8E-82 T 28-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CO689_RS04795 823626d29b94b79174a54d4f068f1d28 272 SUPERFAMILY SSF53474 11 131 5.67E-30 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CO689_RS04795 823626d29b94b79174a54d4f068f1d28 272 SUPERFAMILY SSF53474 175 254 5.67E-30 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CO689_RS04795 823626d29b94b79174a54d4f068f1d28 272 Pfam PF07859 alpha/beta hydrolase fold 31 249 8.5E-17 T 28-03-2018 IPR013094 Alpha/beta hydrolase fold-3 GO:0008152|GO:0016787 CO689_RS04795 823626d29b94b79174a54d4f068f1d28 272 Gene3D G3DSA:3.40.50.1820 1 271 1.6E-33 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CO689_RS01445 8aff32b76c376ea5c27c150393988908 240 PIRSF PIRSF039085 1 240 4.3E-116 T 28-03-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 CO689_RS01445 8aff32b76c376ea5c27c150393988908 240 SUPERFAMILY SSF52540 1 235 3.17E-81 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CO689_RS01445 8aff32b76c376ea5c27c150393988908 240 Gene3D G3DSA:3.40.50.300 1 239 8.5E-77 T 28-03-2018 CO689_RS01445 8aff32b76c376ea5c27c150393988908 240 Pfam PF00005 ABC transporter 17 165 3.8E-38 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CO689_RS01445 8aff32b76c376ea5c27c150393988908 240 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CO689_RS01445 8aff32b76c376ea5c27c150393988908 240 SMART SM00382 26 214 2.2E-15 T 28-03-2018 IPR003593 AAA+ ATPase domain CO689_RS11540 82e82f29e499e72c693e1f9df1b5b3c9 243 Gene3D G3DSA:3.30.160.20 171 243 5.3E-19 T 28-03-2018 CO689_RS11540 82e82f29e499e72c693e1f9df1b5b3c9 243 ProSitePatterns PS00517 Ribonuclease III family signature. 56 64 - T 28-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 CO689_RS11540 82e82f29e499e72c693e1f9df1b5b3c9 243 Gene3D G3DSA:1.10.1520.10 16 165 4.4E-40 T 28-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 CO689_RS11540 82e82f29e499e72c693e1f9df1b5b3c9 243 Pfam PF00035 Double-stranded RNA binding motif 174 238 7.5E-15 T 28-03-2018 IPR014720 Double-stranded RNA-binding domain CO689_RS11540 82e82f29e499e72c693e1f9df1b5b3c9 243 SMART SM00358 173 240 9.7E-19 T 28-03-2018 IPR014720 Double-stranded RNA-binding domain CO689_RS11540 82e82f29e499e72c693e1f9df1b5b3c9 243 Pfam PF14622 Ribonuclease-III-like 33 160 3.8E-35 T 28-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 CO689_RS11540 82e82f29e499e72c693e1f9df1b5b3c9 243 Hamap MF_00104 Ribonuclease 3 [rnc]. 17 236 29.308 T 28-03-2018 IPR011907 Ribonuclease III GO:0003723|GO:0004525|GO:0016075 Reactome: R-HSA-203927 CO689_RS11540 82e82f29e499e72c693e1f9df1b5b3c9 243 SMART SM00535 32 167 4.2E-52 T 28-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 CO689_RS11540 82e82f29e499e72c693e1f9df1b5b3c9 243 SUPERFAMILY SSF69065 13 175 3.49E-49 T 28-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 CO689_RS11540 82e82f29e499e72c693e1f9df1b5b3c9 243 TIGRFAM TIGR02191 RNaseIII: ribonuclease III 24 237 4.3E-74 T 28-03-2018 IPR011907 Ribonuclease III GO:0003723|GO:0004525|GO:0016075 Reactome: R-HSA-203927 CO689_RS11540 82e82f29e499e72c693e1f9df1b5b3c9 243 SUPERFAMILY SSF54768 160 240 1.49E-20 T 28-03-2018 CO689_RS09705 bfa8e7683d9cd8f6bf88999478383d91 61 Gene3D G3DSA:1.20.5.1070 1 59 2.9E-5 T 28-03-2018 CO689_RS06730 6b5418f09be6ad7066b8883a21f19bac 133 SUPERFAMILY SSF52788 3 129 1.57E-45 T 28-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily CO689_RS06730 6b5418f09be6ad7066b8883a21f19bac 133 TIGRFAM TIGR02691 arsC_pI258_fam: arsenate reductase (thioredoxin) 6 128 5.8E-66 T 28-03-2018 IPR014064 Arsenate reductase ArsC GO:0004725|GO:0030612|GO:0046685 CO689_RS06730 6b5418f09be6ad7066b8883a21f19bac 133 Gene3D G3DSA:3.40.50.2300 1 131 1.2E-42 T 28-03-2018 CO689_RS06730 6b5418f09be6ad7066b8883a21f19bac 133 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 6 128 2.0E-25 T 28-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily CO689_RS06730 6b5418f09be6ad7066b8883a21f19bac 133 Hamap MF_01624 Protein ArsC [arsC]. 1 131 47.898 T 28-03-2018 IPR014064 Arsenate reductase ArsC GO:0004725|GO:0030612|GO:0046685 CO689_RS06730 6b5418f09be6ad7066b8883a21f19bac 133 SMART SM00226 4 131 3.8E-61 T 28-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily CO689_RS10630 682f3cac606982ce4af7378b5d741b16 106 SMART SM00418 8 86 1.6E-21 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CO689_RS10630 682f3cac606982ce4af7378b5d741b16 106 Gene3D G3DSA:1.10.10.10 1 93 1.1E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS10630 682f3cac606982ce4af7378b5d741b16 106 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 10 25 1.9E-14 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CO689_RS10630 682f3cac606982ce4af7378b5d741b16 106 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 29 40 1.9E-14 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CO689_RS10630 682f3cac606982ce4af7378b5d741b16 106 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 42 57 1.9E-14 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CO689_RS10630 682f3cac606982ce4af7378b5d741b16 106 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 57 72 1.9E-14 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CO689_RS10630 682f3cac606982ce4af7378b5d741b16 106 ProSitePatterns PS00846 Bacterial regulatory proteins, arsR family signature. 31 49 - T 28-03-2018 IPR018334 ArsR-type transcription regulator, HTH motif GO:0003700|GO:0005622|GO:0006355 CO689_RS10630 682f3cac606982ce4af7378b5d741b16 106 SUPERFAMILY SSF46785 1 86 1.78E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS10630 682f3cac606982ce4af7378b5d741b16 106 Pfam PF01022 Bacterial regulatory protein, arsR family 15 61 4.6E-14 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CO689_RS10665 cdee517af2bbad89b07bcbb097d1268e 249 Pfam PF00455 DeoR C terminal sensor domain 76 232 5.4E-47 T 28-03-2018 IPR014036 DeoR C-terminal sensor domain CO689_RS10665 cdee517af2bbad89b07bcbb097d1268e 249 SMART SM00420 7 59 5.8E-20 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CO689_RS10665 cdee517af2bbad89b07bcbb097d1268e 249 Pfam PF08220 DeoR-like helix-turn-helix domain 7 62 1.1E-18 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CO689_RS10665 cdee517af2bbad89b07bcbb097d1268e 249 ProSitePatterns PS00894 DeoR-type HTH domain signature. 7 41 - T 28-03-2018 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 CO689_RS10665 cdee517af2bbad89b07bcbb097d1268e 249 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 25 39 8.8E-8 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CO689_RS10665 cdee517af2bbad89b07bcbb097d1268e 249 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 39 57 8.8E-8 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CO689_RS10665 cdee517af2bbad89b07bcbb097d1268e 249 Gene3D G3DSA:3.40.50.1360 74 239 4.1E-34 T 28-03-2018 CO689_RS10665 cdee517af2bbad89b07bcbb097d1268e 249 SUPERFAMILY SSF46785 6 65 3.5E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS10665 cdee517af2bbad89b07bcbb097d1268e 249 Gene3D G3DSA:1.10.10.10 2 69 5.9E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS10665 cdee517af2bbad89b07bcbb097d1268e 249 SUPERFAMILY SSF100950 75 233 7.91E-29 T 28-03-2018 CO689_RS10665 cdee517af2bbad89b07bcbb097d1268e 249 SMART SM01134 74 233 2.4E-61 T 28-03-2018 CO689_RS09960 2078c7a5383ae00d6c4a6dbf5245f64b 494 PRINTS PR00481 Cytosol aminopeptidase signature 366 381 1.4E-46 T 28-03-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 CO689_RS09960 2078c7a5383ae00d6c4a6dbf5245f64b 494 PRINTS PR00481 Cytosol aminopeptidase signature 316 337 1.4E-46 T 28-03-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 CO689_RS09960 2078c7a5383ae00d6c4a6dbf5245f64b 494 PRINTS PR00481 Cytosol aminopeptidase signature 257 274 1.4E-46 T 28-03-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 CO689_RS09960 2078c7a5383ae00d6c4a6dbf5245f64b 494 PRINTS PR00481 Cytosol aminopeptidase signature 279 300 1.4E-46 T 28-03-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 CO689_RS09960 2078c7a5383ae00d6c4a6dbf5245f64b 494 PRINTS PR00481 Cytosol aminopeptidase signature 338 358 1.4E-46 T 28-03-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 CO689_RS09960 2078c7a5383ae00d6c4a6dbf5245f64b 494 Gene3D G3DSA:3.40.630.10 165 494 3.5E-113 T 28-03-2018 CO689_RS09960 2078c7a5383ae00d6c4a6dbf5245f64b 494 SUPERFAMILY SSF53187 176 493 2.1E-102 T 28-03-2018 CO689_RS09960 2078c7a5383ae00d6c4a6dbf5245f64b 494 Gene3D G3DSA:3.40.220.10 2 156 1.0E-9 T 28-03-2018 CO689_RS09960 2078c7a5383ae00d6c4a6dbf5245f64b 494 Pfam PF02789 Cytosol aminopeptidase family, N-terminal domain 56 147 2.5E-9 T 28-03-2018 IPR008283 Peptidase M17, leucyl aminopeptidase, N-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 CO689_RS09960 2078c7a5383ae00d6c4a6dbf5245f64b 494 SUPERFAMILY SSF52949 1 178 2.77E-18 T 28-03-2018 CO689_RS09960 2078c7a5383ae00d6c4a6dbf5245f64b 494 Pfam PF00883 Cytosol aminopeptidase family, catalytic domain 180 487 1.9E-101 T 28-03-2018 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 CO689_RS09960 2078c7a5383ae00d6c4a6dbf5245f64b 494 ProSitePatterns PS00631 Cytosol aminopeptidase signature. 342 349 - T 28-03-2018 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 CO689_RS10530 2bb5a1eee0fda39913144adfb981418b 270 TIGRFAM TIGR03695 menH_SHCHC: 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase 16 263 4.2E-83 T 28-03-2018 IPR022485 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase GO:0009234|GO:0070205 KEGG: 00130+4.2.99.20|MetaCyc: PWY-5837 CO689_RS10530 2bb5a1eee0fda39913144adfb981418b 270 SUPERFAMILY SSF53474 9 265 3.89E-43 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CO689_RS10530 2bb5a1eee0fda39913144adfb981418b 270 Hamap MF_01660 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase [menH]. 15 264 34.559 T 28-03-2018 IPR022485 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase GO:0009234|GO:0070205 KEGG: 00130+4.2.99.20|MetaCyc: PWY-5837 CO689_RS10530 2bb5a1eee0fda39913144adfb981418b 270 Gene3D G3DSA:3.40.50.1820 1 269 1.3E-47 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CO689_RS10530 2bb5a1eee0fda39913144adfb981418b 270 Pfam PF12697 Alpha/beta hydrolase family 18 255 1.7E-19 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CO689_RS07770 337c5d81a3449c26a7e77f159ebf4a96 179 Pfam PF00156 Phosphoribosyl transferase domain 14 159 5.2E-25 T 28-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 CO689_RS07770 337c5d81a3449c26a7e77f159ebf4a96 179 TIGRFAM TIGR01203 HGPRTase: hypoxanthine phosphoribosyltransferase 8 172 2.3E-65 T 28-03-2018 IPR005904 Hypoxanthine phosphoribosyl transferase GO:0004422|GO:0005737|GO:0006166 KEGG: 00230+2.4.2.8|KEGG: 00983+2.4.2.8|MetaCyc: PWY-6599|MetaCyc: PWY-6609|MetaCyc: PWY-6610|MetaCyc: PWY-6620 CO689_RS07770 337c5d81a3449c26a7e77f159ebf4a96 179 Gene3D G3DSA:3.40.50.2020 1 179 2.3E-48 T 28-03-2018 CO689_RS07770 337c5d81a3449c26a7e77f159ebf4a96 179 SUPERFAMILY SSF53271 3 177 5.64E-58 T 28-03-2018 IPR029057 Phosphoribosyltransferase-like CO689_RS02210 20b3b51e4b93dfccf968ffed7510c1e7 460 PRINTS PR00415 Aconitase family signature 282 296 3.9E-44 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CO689_RS02210 20b3b51e4b93dfccf968ffed7510c1e7 460 PRINTS PR00415 Aconitase family signature 208 221 3.9E-44 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CO689_RS02210 20b3b51e4b93dfccf968ffed7510c1e7 460 PRINTS PR00415 Aconitase family signature 81 94 3.9E-44 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CO689_RS02210 20b3b51e4b93dfccf968ffed7510c1e7 460 PRINTS PR00415 Aconitase family signature 118 131 3.9E-44 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CO689_RS02210 20b3b51e4b93dfccf968ffed7510c1e7 460 PRINTS PR00415 Aconitase family signature 194 207 3.9E-44 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CO689_RS02210 20b3b51e4b93dfccf968ffed7510c1e7 460 PRINTS PR00415 Aconitase family signature 388 401 3.9E-44 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CO689_RS02210 20b3b51e4b93dfccf968ffed7510c1e7 460 PRINTS PR00415 Aconitase family signature 107 115 3.9E-44 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CO689_RS02210 20b3b51e4b93dfccf968ffed7510c1e7 460 PRINTS PR00415 Aconitase family signature 332 343 3.9E-44 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CO689_RS02210 20b3b51e4b93dfccf968ffed7510c1e7 460 PRINTS PR00415 Aconitase family signature 132 147 3.9E-44 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CO689_RS02210 20b3b51e4b93dfccf968ffed7510c1e7 460 Gene3D G3DSA:3.30.499.10 312 460 4.7E-48 T 28-03-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 CO689_RS02210 20b3b51e4b93dfccf968ffed7510c1e7 460 Gene3D G3DSA:3.40.1060.10 154 284 2.9E-43 T 28-03-2018 IPR015932 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 2 GO:0008152 KEGG: 00290+4.2.1.33 CO689_RS02210 20b3b51e4b93dfccf968ffed7510c1e7 460 ProSitePatterns PS01244 Aconitase family signature 2. 388 401 - T 28-03-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 CO689_RS02210 20b3b51e4b93dfccf968ffed7510c1e7 460 SUPERFAMILY SSF53732 1 457 2.35E-160 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CO689_RS02210 20b3b51e4b93dfccf968ffed7510c1e7 460 ProSitePatterns PS00450 Aconitase family signature 1. 328 344 - T 28-03-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 CO689_RS02210 20b3b51e4b93dfccf968ffed7510c1e7 460 Pfam PF00330 Aconitase family (aconitate hydratase) 7 446 1.1E-149 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CO689_RS02210 20b3b51e4b93dfccf968ffed7510c1e7 460 TIGRFAM TIGR00170 leuC: 3-isopropylmalate dehydratase, large subunit 1 453 6.3E-210 T 28-03-2018 IPR004430 3-isopropylmalate dehydratase, large subunit GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 CO689_RS02210 20b3b51e4b93dfccf968ffed7510c1e7 460 Hamap MF_01026 3-isopropylmalate dehydratase large subunit [leuC]. 1 455 56.943 T 28-03-2018 IPR004430 3-isopropylmalate dehydratase, large subunit GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 CO689_RS02210 20b3b51e4b93dfccf968ffed7510c1e7 460 Gene3D G3DSA:3.30.499.10 1 153 8.8E-42 T 28-03-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 CO689_RS03940 b175936b30c573e612c4e6ae8c42a80d 349 Gene3D G3DSA:3.30.565.10 173 346 2.3E-25 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CO689_RS03940 b175936b30c573e612c4e6ae8c42a80d 349 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 258 345 8.6E-10 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CO689_RS03940 b175936b30c573e612c4e6ae8c42a80d 349 PIRSF PIRSF037432 1 345 8.8E-183 T 28-03-2018 IPR017203 Signal transduction histidine kinase, NreB GO:0000155|GO:0004673|GO:0005506|GO:0005524|GO:0005737|GO:0018106 CO689_RS03940 b175936b30c573e612c4e6ae8c42a80d 349 Pfam PF07730 Histidine kinase 150 215 2.2E-14 T 28-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 CO689_RS03940 b175936b30c573e612c4e6ae8c42a80d 349 SMART SM00387 253 347 5.0E-12 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CO689_RS03940 b175936b30c573e612c4e6ae8c42a80d 349 SUPERFAMILY SSF55874 222 344 3.93E-23 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CO689_RS03940 b175936b30c573e612c4e6ae8c42a80d 349 PRINTS PR00344 Bacterial sensor protein C-terminal signature 289 303 9.5E-7 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CO689_RS03940 b175936b30c573e612c4e6ae8c42a80d 349 PRINTS PR00344 Bacterial sensor protein C-terminal signature 307 325 9.5E-7 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CO689_RS03940 b175936b30c573e612c4e6ae8c42a80d 349 PRINTS PR00344 Bacterial sensor protein C-terminal signature 331 344 9.5E-7 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CO689_RS08410 120015e0ad427579522d92ca6676a617 413 SUPERFAMILY SSF55729 2 164 6.89E-53 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CO689_RS08410 120015e0ad427579522d92ca6676a617 413 Pfam PF02388 FemAB family 8 413 7.0E-140 T 28-03-2018 IPR003447 FemABX peptidyl transferase GO:0016755|GO:0044038 CO689_RS08410 120015e0ad427579522d92ca6676a617 413 Gene3D G3DSA:3.40.630.30 1 167 7.6E-29 T 28-03-2018 CO689_RS08410 120015e0ad427579522d92ca6676a617 413 SUPERFAMILY SSF46589 244 307 4.81E-15 T 28-03-2018 IPR010978 tRNA-binding arm GO:0000166 CO689_RS08410 120015e0ad427579522d92ca6676a617 413 SUPERFAMILY SSF55729 166 244 7.42E-37 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CO689_RS08410 120015e0ad427579522d92ca6676a617 413 SUPERFAMILY SSF55729 310 410 7.42E-37 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CO689_RS08410 120015e0ad427579522d92ca6676a617 413 Gene3D G3DSA:3.40.630.30 168 389 1.0E-34 T 28-03-2018 CO689_RS10050 5e62366c255ebe9e57a43b828ff2f25f 375 Gene3D G3DSA:3.20.20.70 3 358 9.9E-85 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CO689_RS10050 5e62366c255ebe9e57a43b828ff2f25f 375 SUPERFAMILY SSF51395 1 345 4.28E-82 T 28-03-2018 CO689_RS10050 5e62366c255ebe9e57a43b828ff2f25f 375 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 8 338 4.2E-67 T 28-03-2018 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 CO689_RS11360 7a59bf46a6360f915862e05ba56bbda1 305 Hamap MF_00224 Dihydroorotate dehydrogenase [pyrD]. 4 300 38.985 T 28-03-2018 IPR024920 Dihydroorotate dehydrogenase, class 1 GO:0004152|GO:0005737|GO:0006221 CO689_RS11360 7a59bf46a6360f915862e05ba56bbda1 305 ProSitePatterns PS00912 Dihydroorotate dehydrogenase signature 2. 238 258 - T 28-03-2018 IPR001295 Dihydroorotate dehydrogenase, conserved site GO:0004152|GO:0006207|GO:0055114 Reactome: R-HSA-500753 CO689_RS11360 7a59bf46a6360f915862e05ba56bbda1 305 TIGRFAM TIGR01037 pyrD_sub1_fam: dihydroorotate dehydrogenase family protein 4 296 6.0E-114 T 28-03-2018 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 CO689_RS11360 7a59bf46a6360f915862e05ba56bbda1 305 PIRSF PIRSF000164 1 297 8.3E-84 T 28-03-2018 IPR012135 Dihydroorotate dehydrogenase, class 1/ 2 GO:0004152|GO:0006222|GO:0055114 CO689_RS11360 7a59bf46a6360f915862e05ba56bbda1 305 ProSitePatterns PS00911 Dihydroorotate dehydrogenase signature 1. 40 59 - T 28-03-2018 IPR001295 Dihydroorotate dehydrogenase, conserved site GO:0004152|GO:0006207|GO:0055114 Reactome: R-HSA-500753 CO689_RS11360 7a59bf46a6360f915862e05ba56bbda1 305 Pfam PF01180 Dihydroorotate dehydrogenase 4 285 1.0E-88 T 28-03-2018 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 CO689_RS11360 7a59bf46a6360f915862e05ba56bbda1 305 SUPERFAMILY SSF51395 1 298 7.0E-82 T 28-03-2018 CO689_RS11360 7a59bf46a6360f915862e05ba56bbda1 305 Gene3D G3DSA:3.20.20.70 1 305 1.8E-60 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CO689_RS05500 0a1d12cf9b4b3001b8a358727be02146 532 Gene3D G3DSA:3.20.20.70 86 531 1.3E-89 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CO689_RS05500 0a1d12cf9b4b3001b8a358727be02146 532 SUPERFAMILY SSF51395 165 522 5.86E-109 T 28-03-2018 CO689_RS05500 0a1d12cf9b4b3001b8a358727be02146 532 SUPERFAMILY SSF51395 13 128 5.86E-109 T 28-03-2018 CO689_RS05500 0a1d12cf9b4b3001b8a358727be02146 532 PIRSF PIRSF500060 1 531 1.8E-211 T 28-03-2018 IPR027283 Glutamate synthase large subunit-like protein, bacteria CO689_RS05500 0a1d12cf9b4b3001b8a358727be02146 532 PIRSF PIRSF006429 1 530 1.9E-153 T 28-03-2018 IPR024188 Glutamate synthase large subunit-like protein CO689_RS05500 0a1d12cf9b4b3001b8a358727be02146 532 Pfam PF01645 Conserved region in glutamate synthase 120 493 9.5E-103 T 28-03-2018 IPR002932 Glutamate synthase domain GO:0006537|GO:0015930|GO:0016638|GO:0055114 CO689_RS05060 a3119f14f14c3b248058311cc1304a3e 321 Gene3D G3DSA:3.40.50.10440 11 178 9.5E-68 T 28-03-2018 CO689_RS05060 a3119f14f14c3b248058311cc1304a3e 321 TIGRFAM TIGR02363 dhaK1: dihydroxyacetone kinase, DhaK subunit 1 319 1.0E-135 T 28-03-2018 IPR012736 Dihydroxyacetone kinase DhaK, subunit 1 CO689_RS05060 a3119f14f14c3b248058311cc1304a3e 321 Gene3D G3DSA:3.30.1180.20 179 321 9.6E-41 T 28-03-2018 CO689_RS05060 a3119f14f14c3b248058311cc1304a3e 321 SUPERFAMILY SSF82549 1 320 3.4E-113 T 28-03-2018 CO689_RS05060 a3119f14f14c3b248058311cc1304a3e 321 Pfam PF02733 Dak1 domain 17 317 2.9E-115 T 28-03-2018 IPR004006 DhaK domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 CO689_RS05730 aded7676d516453e1d4286697150f584 356 SMART SM00854 62 287 7.8E-18 T 28-03-2018 IPR019079 Capsule synthesis protein, CapA CO689_RS05730 aded7676d516453e1d4286697150f584 356 SUPERFAMILY SSF56300 61 286 2.58E-13 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CO689_RS05730 aded7676d516453e1d4286697150f584 356 Pfam PF09587 Bacterial capsule synthesis protein PGA_cap 63 286 3.1E-24 T 28-03-2018 IPR019079 Capsule synthesis protein, CapA CO689_RS05730 aded7676d516453e1d4286697150f584 356 Gene3D G3DSA:3.60.21.10 40 344 1.0E-25 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CO689_RS13755 aa76867db65660f94f70031235198944 66 Hamap MF_00514 50S ribosomal protein L35 [rpmI]. 1 64 19.3 T 28-03-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 CO689_RS13755 aa76867db65660f94f70031235198944 66 Pfam PF01632 Ribosomal protein L35 2 62 9.5E-26 T 28-03-2018 IPR021137 Ribosomal protein L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CO689_RS13755 aa76867db65660f94f70031235198944 66 TIGRFAM TIGR00001 rpmI_bact: ribosomal protein bL35 2 64 1.7E-26 T 28-03-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 CO689_RS13755 aa76867db65660f94f70031235198944 66 ProSitePatterns PS00936 Ribosomal protein L35 signature. 5 31 - T 28-03-2018 IPR018265 Ribosomal protein L35, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CO689_RS13755 aa76867db65660f94f70031235198944 66 SUPERFAMILY SSF143034 2 64 1.12E-22 T 28-03-2018 CO689_RS13755 aa76867db65660f94f70031235198944 66 PRINTS PR00064 Ribosomal protein L35 signature 36 54 9.4E-22 T 28-03-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 CO689_RS13755 aa76867db65660f94f70031235198944 66 PRINTS PR00064 Ribosomal protein L35 signature 21 35 9.4E-22 T 28-03-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 CO689_RS13755 aa76867db65660f94f70031235198944 66 PRINTS PR00064 Ribosomal protein L35 signature 3 20 9.4E-22 T 28-03-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 CO689_RS03670 bbbaf2ca024341ed2604a4eeb59747ad 108 Pfam PF02694 Uncharacterised BCR, YnfA/UPF0060 family 2 107 2.6E-38 T 28-03-2018 IPR003844 Uncharacterised protein family UPF0060 GO:0016020 CO689_RS03670 bbbaf2ca024341ed2604a4eeb59747ad 108 Hamap MF_00010 UPF0060 membrane protein YnfA [ynfA]. 2 107 20.103 T 28-03-2018 IPR003844 Uncharacterised protein family UPF0060 GO:0016020 CO689_RS03670 bbbaf2ca024341ed2604a4eeb59747ad 108 SUPERFAMILY SSF103481 8 107 7.98E-11 T 28-03-2018 CO689_RS07415 d388063c4fb0f4748806f97d02046e4b 382 PIRSF PIRSF001434 1 381 2.9E-145 T 28-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 CO689_RS07415 d388063c4fb0f4748806f97d02046e4b 382 Gene3D G3DSA:3.40.640.10 1 246 2.6E-58 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CO689_RS07415 d388063c4fb0f4748806f97d02046e4b 382 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 4 377 9.1E-151 T 28-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 CO689_RS07415 d388063c4fb0f4748806f97d02046e4b 382 SUPERFAMILY SSF53383 8 379 1.51E-113 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CO689_RS07415 d388063c4fb0f4748806f97d02046e4b 382 Gene3D G3DSA:3.90.1150.10 247 382 3.2E-50 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CO689_RS01360 55fc2f50cc4f425703f6044e2d02eef7 319 Gene3D G3DSA:1.10.4030.10 29 133 6.2E-6 T 28-03-2018 CO689_RS01360 55fc2f50cc4f425703f6044e2d02eef7 319 SUPERFAMILY SSF109998 66 157 1.73E-13 T 28-03-2018 IPR027304 Trigger factor/SurA domain CO689_RS01360 55fc2f50cc4f425703f6044e2d02eef7 319 SUPERFAMILY SSF54534 140 244 4.27E-26 T 28-03-2018 CO689_RS01360 55fc2f50cc4f425703f6044e2d02eef7 319 Gene3D G3DSA:3.10.50.40 134 245 4.2E-30 T 28-03-2018 CO689_RS01360 55fc2f50cc4f425703f6044e2d02eef7 319 Pfam PF13616 PPIC-type PPIASE domain 130 246 2.0E-28 T 28-03-2018 CO689_RS04705 8d3d6fd5b1038101a2d904da942993bf 599 ProSitePatterns PS00608 Glycosyl hydrolases family 2 acid/base catalyst. 397 411 - T 28-03-2018 IPR023232 Glycoside hydrolase, family 2, active site KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-6798695 CO689_RS04705 8d3d6fd5b1038101a2d904da942993bf 599 ProSitePatterns PS00719 Glycosyl hydrolases family 2 signature 1. 326 351 - T 28-03-2018 IPR023230 Glycoside hydrolase, family 2, conserved site KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-6798695 CO689_RS04705 8d3d6fd5b1038101a2d904da942993bf 599 SUPERFAMILY SSF51445 276 591 3.19E-83 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CO689_RS04705 8d3d6fd5b1038101a2d904da942993bf 599 Gene3D G3DSA:2.60.120.260 1 180 4.5E-41 T 28-03-2018 IPR008979 Galactose-binding domain-like CO689_RS04705 8d3d6fd5b1038101a2d904da942993bf 599 Pfam PF00703 Glycosyl hydrolases family 2 184 274 2.1E-11 T 28-03-2018 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 CO689_RS04705 8d3d6fd5b1038101a2d904da942993bf 599 PRINTS PR00132 Glycosyl hydrolase family 2 signature 285 299 3.9E-17 T 28-03-2018 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-6798695 CO689_RS04705 8d3d6fd5b1038101a2d904da942993bf 599 PRINTS PR00132 Glycosyl hydrolase family 2 signature 397 412 3.9E-17 T 28-03-2018 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-6798695 CO689_RS04705 8d3d6fd5b1038101a2d904da942993bf 599 PRINTS PR00132 Glycosyl hydrolase family 2 signature 316 334 3.9E-17 T 28-03-2018 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-6798695 CO689_RS04705 8d3d6fd5b1038101a2d904da942993bf 599 PRINTS PR00132 Glycosyl hydrolase family 2 signature 498 513 3.9E-17 T 28-03-2018 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-6798695 CO689_RS04705 8d3d6fd5b1038101a2d904da942993bf 599 SUPERFAMILY SSF49303 183 275 1.41E-21 T 28-03-2018 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 CO689_RS04705 8d3d6fd5b1038101a2d904da942993bf 599 SUPERFAMILY SSF49785 1 180 4.82E-51 T 28-03-2018 IPR008979 Galactose-binding domain-like CO689_RS04705 8d3d6fd5b1038101a2d904da942993bf 599 Pfam PF02836 Glycosyl hydrolases family 2, TIM barrel domain 276 591 2.8E-79 T 28-03-2018 IPR006103 Glycoside hydrolase family 2, catalytic domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-6798695 CO689_RS04705 8d3d6fd5b1038101a2d904da942993bf 599 Pfam PF02837 Glycosyl hydrolases family 2, sugar binding domain 14 180 1.7E-23 T 28-03-2018 IPR006104 Glycosyl hydrolases family 2, sugar binding domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 CO689_RS04705 8d3d6fd5b1038101a2d904da942993bf 599 Gene3D G3DSA:3.20.20.80 276 592 5.5E-58 T 28-03-2018 CO689_RS04705 8d3d6fd5b1038101a2d904da942993bf 599 Gene3D G3DSA:2.60.40.10 181 275 9.5E-22 T 28-03-2018 IPR013783 Immunoglobulin-like fold CO689_RS07745 e807f94c82a3f8d2349b82e3c52f6881 397 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 4 209 3.5E-21 T 28-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CO689_RS07745 e807f94c82a3f8d2349b82e3c52f6881 397 Gene3D G3DSA:1.10.287.1080 235 354 2.8E-34 T 28-03-2018 CO689_RS07745 e807f94c82a3f8d2349b82e3c52f6881 397 SUPERFAMILY SSF53790 4 267 2.62E-27 T 28-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CO689_RS07745 e807f94c82a3f8d2349b82e3c52f6881 397 Gene3D G3DSA:3.40.1010.10 1 122 8.2E-17 T 28-03-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CO689_RS07745 e807f94c82a3f8d2349b82e3c52f6881 397 SUPERFAMILY SSF101386 235 338 3.74E-22 T 28-03-2018 CO689_RS07745 e807f94c82a3f8d2349b82e3c52f6881 397 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 259 332 3.6E-28 T 28-03-2018 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core CO689_RS07745 e807f94c82a3f8d2349b82e3c52f6881 397 PIRSF PIRSF002845 1 384 2.5E-152 T 28-03-2018 IPR024180 Bifunctional tetrapyrrole methylase/MazG NTP pyrophosphohydrolase, predicted CO689_RS11995 48646db06f9e998bbbd210aae572b805 321 Gene3D G3DSA:3.40.50.300 5 204 7.6E-67 T 28-03-2018 CO689_RS11995 48646db06f9e998bbbd210aae572b805 321 SUPERFAMILY SSF52540 7 60 1.24E-10 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CO689_RS11995 48646db06f9e998bbbd210aae572b805 321 SUPERFAMILY SSF52540 126 257 1.24E-10 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CO689_RS11995 48646db06f9e998bbbd210aae572b805 321 Hamap MF_00185 tRNA dimethylallyltransferase [miaA]. 9 305 29.047 T 28-03-2018 IPR018022 tRNA dimethylallyltransferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 CO689_RS11995 48646db06f9e998bbbd210aae572b805 321 Pfam PF01715 IPP transferase 42 290 4.9E-83 T 28-03-2018 IPR018022 tRNA dimethylallyltransferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 CO689_RS11995 48646db06f9e998bbbd210aae572b805 321 Gene3D G3DSA:1.10.287.890 206 286 2.3E-27 T 28-03-2018 CO689_RS11995 48646db06f9e998bbbd210aae572b805 321 TIGRFAM TIGR00174 miaA: tRNA dimethylallyltransferase 10 297 4.1E-99 T 28-03-2018 IPR018022 tRNA dimethylallyltransferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 CO689_RS11995 48646db06f9e998bbbd210aae572b805 321 SUPERFAMILY SSF52540 9 142 3.78E-19 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CO689_RS06740 b3ba2e44a590de9055ff8df3d129b508 205 TIGRFAM TIGR00779 cad: cadmium resistance transporter family protein 12 205 1.1E-87 T 28-03-2018 IPR004676 Cadmium resistance transporter CO689_RS06740 b3ba2e44a590de9055ff8df3d129b508 205 Pfam PF03596 Cadmium resistance transporter 12 203 5.8E-88 T 28-03-2018 IPR004676 Cadmium resistance transporter CO689_RS07465 907ac9e22b95f3d256ed43cfc31b4cb8 294 Pfam PF03466 LysR substrate binding domain 88 283 2.2E-16 T 28-03-2018 IPR005119 LysR, substrate-binding CO689_RS07465 907ac9e22b95f3d256ed43cfc31b4cb8 294 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 9.5E-9 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CO689_RS07465 907ac9e22b95f3d256ed43cfc31b4cb8 294 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 9.5E-9 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CO689_RS07465 907ac9e22b95f3d256ed43cfc31b4cb8 294 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 9.5E-9 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CO689_RS07465 907ac9e22b95f3d256ed43cfc31b4cb8 294 SUPERFAMILY SSF46785 1 85 7.79E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS07465 907ac9e22b95f3d256ed43cfc31b4cb8 294 Gene3D G3DSA:1.10.10.10 1 82 3.5E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS07465 907ac9e22b95f3d256ed43cfc31b4cb8 294 SUPERFAMILY SSF53850 90 288 2.71E-15 T 28-03-2018 CO689_RS07465 907ac9e22b95f3d256ed43cfc31b4cb8 294 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 1.3E-20 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CO689_RS07465 907ac9e22b95f3d256ed43cfc31b4cb8 294 Gene3D G3DSA:3.40.190.10 84 199 2.1E-11 T 28-03-2018 CO689_RS00240 7806df8c1dea5fb953aba38291cad6b7 216 SUPERFAMILY SSF51366 4 215 2.2E-54 T 28-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 CO689_RS00240 7806df8c1dea5fb953aba38291cad6b7 216 Gene3D G3DSA:3.20.20.70 1 216 3.4E-59 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CO689_RS00240 7806df8c1dea5fb953aba38291cad6b7 216 TIGRFAM TIGR01163 rpe: ribulose-phosphate 3-epimerase 6 216 6.4E-64 T 28-03-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 CO689_RS00240 7806df8c1dea5fb953aba38291cad6b7 216 Pfam PF00834 Ribulose-phosphate 3 epimerase family 6 198 4.0E-57 T 28-03-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 CO689_RS07230 52567e623c3d0b979a12cfb392358a5a 128 ProDom PD458455 UPF0355 MW0363 SE2351 MRSA252 SSP2326 SH2586 SA0372 SAV0387 SACOL0457 SERP0066 1 113 3.0E-23 T 28-03-2018 CO689_RS07230 52567e623c3d0b979a12cfb392358a5a 128 Pfam PF11181 Heat induced stress protein YflT 4 99 3.5E-11 T 28-03-2018 IPR025889 General stress protein 17M-like domain CO689_RS07145 2d7d4cfc91ce9534d922510c81002898 98 Pfam PF01250 Ribosomal protein S6 4 93 4.6E-27 T 28-03-2018 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CO689_RS07145 2d7d4cfc91ce9534d922510c81002898 98 Hamap MF_00360 30S ribosomal protein S6 [rpsF]. 1 96 23.37 T 28-03-2018 IPR020814 Ribosomal protein S6, plastid/chloroplast GO:0003735|GO:0005840|GO:0006412|GO:0019843 CO689_RS07145 2d7d4cfc91ce9534d922510c81002898 98 Gene3D G3DSA:3.30.70.60 2 98 6.5E-30 T 28-03-2018 IPR014717 Translation elongation factor EF1B/ribosomal protein S6 CO689_RS07145 2d7d4cfc91ce9534d922510c81002898 98 TIGRFAM TIGR00166 S6: ribosomal protein bS6 1 95 3.9E-29 T 28-03-2018 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CO689_RS07145 2d7d4cfc91ce9534d922510c81002898 98 SUPERFAMILY SSF54995 1 96 7.33E-34 T 28-03-2018 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CO689_RS13115 9c37d4977b38f733e8a4be80c5c068dc 207 SUPERFAMILY SSF56281 1 196 2.23E-49 T 28-03-2018 IPR001279 Metallo-beta-lactamase CO689_RS13115 9c37d4977b38f733e8a4be80c5c068dc 207 Pfam PF00753 Metallo-beta-lactamase superfamily 13 175 2.1E-30 T 28-03-2018 IPR001279 Metallo-beta-lactamase CO689_RS13115 9c37d4977b38f733e8a4be80c5c068dc 207 SMART SM00849 12 190 7.4E-42 T 28-03-2018 IPR001279 Metallo-beta-lactamase CO689_RS13115 9c37d4977b38f733e8a4be80c5c068dc 207 Gene3D G3DSA:3.60.15.10 1 205 5.8E-42 T 28-03-2018 IPR001279 Metallo-beta-lactamase CO689_RS06950 ac3f7743e4ae786a07d19403976fea33 428 Hamap MF_00011 Adenylosuccinate synthetase [purA]. 1 428 201.157 T 28-03-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 CO689_RS06950 ac3f7743e4ae786a07d19403976fea33 428 SUPERFAMILY SSF52540 1 427 3.08E-171 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CO689_RS06950 ac3f7743e4ae786a07d19403976fea33 428 Gene3D G3DSA:3.90.170.10 265 428 3.3E-67 T 28-03-2018 CO689_RS06950 ac3f7743e4ae786a07d19403976fea33 428 Pfam PF00709 Adenylosuccinate synthetase 4 420 2.1E-176 T 28-03-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 CO689_RS06950 ac3f7743e4ae786a07d19403976fea33 428 ProSitePatterns PS00513 Adenylosuccinate synthetase active site. 131 142 - T 28-03-2018 IPR033128 Adenylosuccinate synthase, active site KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 CO689_RS06950 ac3f7743e4ae786a07d19403976fea33 428 SMART SM00788 3 422 2.6E-281 T 28-03-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 CO689_RS06950 ac3f7743e4ae786a07d19403976fea33 428 ProSitePatterns PS01266 Adenylosuccinate synthetase GTP-binding site. 10 17 - T 28-03-2018 IPR018220 Adenylosuccinate synthase, GTP-binding site GO:0005525 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 CO689_RS06950 ac3f7743e4ae786a07d19403976fea33 428 TIGRFAM TIGR00184 purA: adenylosuccinate synthase 5 424 1.4E-180 T 28-03-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 CO689_RS06950 ac3f7743e4ae786a07d19403976fea33 428 Gene3D G3DSA:3.40.440.10 1 149 1.7E-51 T 28-03-2018 CO689_RS06950 ac3f7743e4ae786a07d19403976fea33 428 Gene3D G3DSA:3.40.440.10 150 264 2.7E-25 T 28-03-2018 CO689_RS13875 104b65c75d8570cfcac573ceb006f730 137 SUPERFAMILY SSF52402 2 137 2.6E-22 T 28-03-2018 CO689_RS13875 104b65c75d8570cfcac573ceb006f730 137 Pfam PF00582 Universal stress protein family 1 137 3.9E-22 T 28-03-2018 IPR006016 UspA GO:0006950 CO689_RS13875 104b65c75d8570cfcac573ceb006f730 137 Gene3D G3DSA:3.40.50.620 1 137 1.2E-23 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CO689_RS13875 104b65c75d8570cfcac573ceb006f730 137 PRINTS PR01438 Universal stress protein signature 115 137 1.4E-12 T 28-03-2018 IPR006015 Universal stress protein A CO689_RS13875 104b65c75d8570cfcac573ceb006f730 137 PRINTS PR01438 Universal stress protein signature 97 109 1.4E-12 T 28-03-2018 IPR006015 Universal stress protein A CO689_RS13875 104b65c75d8570cfcac573ceb006f730 137 PRINTS PR01438 Universal stress protein signature 2 20 1.4E-12 T 28-03-2018 IPR006015 Universal stress protein A CO689_RS13030 52b278957e43807d8df2216f9c229787 157 SUPERFAMILY SSF51230 83 156 4.58E-23 T 28-03-2018 IPR011053 Single hybrid motif CO689_RS13030 52b278957e43807d8df2216f9c229787 157 Gene3D G3DSA:2.40.50.100 5 157 2.7E-18 T 28-03-2018 CO689_RS13030 52b278957e43807d8df2216f9c229787 157 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 86 99 4.2E-16 T 28-03-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 CO689_RS13030 52b278957e43807d8df2216f9c229787 157 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 118 131 4.2E-16 T 28-03-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 CO689_RS13030 52b278957e43807d8df2216f9c229787 157 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 103 117 4.2E-16 T 28-03-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 CO689_RS13030 52b278957e43807d8df2216f9c229787 157 Pfam PF00364 Biotin-requiring enzyme 82 155 2.0E-24 T 28-03-2018 IPR000089 Biotin/lipoyl attachment CO689_RS13030 52b278957e43807d8df2216f9c229787 157 TIGRFAM TIGR00531 BCCP: acetyl-CoA carboxylase, biotin carboxyl carrier protein 1 157 2.0E-50 T 28-03-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 CO689_RS04870 5d15373cbd72008c98262c5af04e7c4a 277 Gene3D G3DSA:2.40.10.10 159 259 3.8E-6 T 28-03-2018 CO689_RS04870 5d15373cbd72008c98262c5af04e7c4a 277 Gene3D G3DSA:2.40.10.10 40 158 9.1E-10 T 28-03-2018 CO689_RS04870 5d15373cbd72008c98262c5af04e7c4a 277 SUPERFAMILY SSF50494 55 249 2.85E-25 T 28-03-2018 IPR009003 Peptidase S1, PA clan CO689_RS04870 5d15373cbd72008c98262c5af04e7c4a 277 Pfam PF13365 Trypsin-like peptidase domain 90 238 1.3E-13 T 28-03-2018 CO689_RS12990 a3fd0363684644ab750a5ca4badf0c09 558 TIGRFAM TIGR00634 recN: DNA repair protein RecN 1 554 8.1E-165 T 28-03-2018 IPR004604 DNA recombination/repair protein RecN GO:0005524|GO:0006281|GO:0006310 CO689_RS12990 a3fd0363684644ab750a5ca4badf0c09 558 PIRSF PIRSF003128 1 557 1.2E-170 T 28-03-2018 IPR004604 DNA recombination/repair protein RecN GO:0005524|GO:0006281|GO:0006310 CO689_RS12990 a3fd0363684644ab750a5ca4badf0c09 558 SUPERFAMILY SSF52540 1 219 3.75E-58 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CO689_RS12990 a3fd0363684644ab750a5ca4badf0c09 558 SUPERFAMILY SSF52540 296 507 1.61E-30 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CO689_RS12990 a3fd0363684644ab750a5ca4badf0c09 558 SUPERFAMILY SSF52540 3 50 1.61E-30 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CO689_RS12990 a3fd0363684644ab750a5ca4badf0c09 558 Gene3D G3DSA:3.40.50.300 1 189 1.4E-27 T 28-03-2018 CO689_RS12990 a3fd0363684644ab750a5ca4badf0c09 558 Gene3D G3DSA:3.40.50.300 207 535 9.1E-17 T 28-03-2018 CO689_RS12990 a3fd0363684644ab750a5ca4badf0c09 558 Pfam PF02463 RecF/RecN/SMC N terminal domain 1 509 2.5E-18 T 28-03-2018 IPR003395 RecF/RecN/SMC, N-terminal CO689_RS07155 c69543a346e66d8a007cdfef2086cbd7 80 Gene3D G3DSA:4.10.640.10 3 80 1.8E-35 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CO689_RS07155 c69543a346e66d8a007cdfef2086cbd7 80 Pfam PF01084 Ribosomal protein S18 23 73 2.9E-29 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CO689_RS07155 c69543a346e66d8a007cdfef2086cbd7 80 PRINTS PR00974 Ribosomal protein S18 family signature 43 50 3.5E-22 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CO689_RS07155 c69543a346e66d8a007cdfef2086cbd7 80 PRINTS PR00974 Ribosomal protein S18 family signature 51 65 3.5E-22 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CO689_RS07155 c69543a346e66d8a007cdfef2086cbd7 80 PRINTS PR00974 Ribosomal protein S18 family signature 65 75 3.5E-22 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CO689_RS07155 c69543a346e66d8a007cdfef2086cbd7 80 PRINTS PR00974 Ribosomal protein S18 family signature 33 43 3.5E-22 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CO689_RS07155 c69543a346e66d8a007cdfef2086cbd7 80 Hamap MF_00270 30S ribosomal protein S18 [rpsR]. 7 78 23.327 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CO689_RS07155 c69543a346e66d8a007cdfef2086cbd7 80 ProDom PD002239 RIBOSOMAL S18 RIBONUCLEOPROTEIN 30S RRNA-BINDING RNA-BINDING CHLOROPLAST PLASTID MITOCHONDRIAL ACETYLATION 25 78 2.0E-24 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CO689_RS07155 c69543a346e66d8a007cdfef2086cbd7 80 TIGRFAM TIGR00165 S18: ribosomal protein bS18 11 78 2.4E-38 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CO689_RS07155 c69543a346e66d8a007cdfef2086cbd7 80 ProSitePatterns PS00057 Ribosomal protein S18 signature. 26 49 - T 28-03-2018 IPR018275 Ribosomal protein S18, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CO689_RS07155 c69543a346e66d8a007cdfef2086cbd7 80 SUPERFAMILY SSF46911 5 78 7.46E-32 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CO689_RS10115 407c602ff5213feced8a3b91504c866c 131 ProDom PD067392 MEMBRANE UPF0344 TRANSMEMBRANE MW0851 BCE1257 SIMILAR YISL SAR0931 BCE33L1051 BT9727_1053 1 121 1.0E-31 T 28-03-2018 IPR010899 Protein of unknown function UPF0344 CO689_RS10115 407c602ff5213feced8a3b91504c866c 131 Hamap MF_01536 UPF0344 protein . 1 125 13.876 T 28-03-2018 IPR010899 Protein of unknown function UPF0344 CO689_RS10115 407c602ff5213feced8a3b91504c866c 131 Pfam PF07457 Protein of unknown function (DUF1516) 2 115 7.8E-33 T 28-03-2018 IPR010899 Protein of unknown function UPF0344 CO689_RS07800 57746795ea28f690d00be404cddfefca 158 ProSitePatterns PS00794 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase signature. 88 99 - T 28-03-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 CO689_RS07800 57746795ea28f690d00be404cddfefca 158 TIGRFAM TIGR01498 folK: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase 4 133 7.8E-50 T 28-03-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 CO689_RS07800 57746795ea28f690d00be404cddfefca 158 SUPERFAMILY SSF55083 1 147 1.44E-56 T 28-03-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 CO689_RS07800 57746795ea28f690d00be404cddfefca 158 Pfam PF01288 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) 5 133 1.0E-41 T 28-03-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 CO689_RS07800 57746795ea28f690d00be404cddfefca 158 Gene3D G3DSA:3.30.70.560 1 156 7.5E-64 T 28-03-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 CO689_RS06840 b03bef2713e3233eba9702a2c83d092a 165 PIRSF PIRSF032209 1 165 1.4E-69 T 28-03-2018 IPR016992 Uncharacterised conserved protein UCP032209 CO689_RS06840 b03bef2713e3233eba9702a2c83d092a 165 Pfam PF07799 Protein of unknown function (DUF1643) 19 154 2.2E-25 T 28-03-2018 IPR012441 Protein of unknown function DUF1643 CO689_RS08325 6d16bf6389de7c3e12954c61d8f39e61 432 SMART SM00471 60 190 1.6E-11 T 28-03-2018 IPR003607 HD/PDEase domain CO689_RS08325 6d16bf6389de7c3e12954c61d8f39e61 432 SUPERFAMILY SSF109604 9 417 1.11E-112 T 28-03-2018 CO689_RS08325 6d16bf6389de7c3e12954c61d8f39e61 432 Pfam PF01966 HD domain 64 184 2.3E-15 T 28-03-2018 IPR006674 HD domain CO689_RS08325 6d16bf6389de7c3e12954c61d8f39e61 432 Gene3D G3DSA:1.10.3210.10 13 315 1.9E-79 T 28-03-2018 CO689_RS06435 70e07951ab42e6c8a1ebc4fc7b7dfa69 243 TIGRFAM TIGR00502 nagB: glucosamine-6-phosphate deaminase 1 237 4.9E-71 T 28-03-2018 IPR004547 Glucosamine-6-phosphate isomerase GO:0004342|GO:0006044 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906|Reactome: R-HSA-70326 CO689_RS06435 70e07951ab42e6c8a1ebc4fc7b7dfa69 243 SUPERFAMILY SSF100950 1 236 1.81E-78 T 28-03-2018 CO689_RS06435 70e07951ab42e6c8a1ebc4fc7b7dfa69 243 Gene3D G3DSA:3.40.50.1360 1 243 1.5E-63 T 28-03-2018 CO689_RS06435 70e07951ab42e6c8a1ebc4fc7b7dfa69 243 Pfam PF01182 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase 12 228 3.8E-21 T 28-03-2018 IPR006148 Glucosamine/galactosamine-6-phosphate isomerase GO:0005975 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906 CO689_RS06435 70e07951ab42e6c8a1ebc4fc7b7dfa69 243 Hamap MF_01241 Glucosamine-6-phosphate deaminase [nagB]. 1 242 38.056 T 28-03-2018 IPR004547 Glucosamine-6-phosphate isomerase GO:0004342|GO:0006044 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906|Reactome: R-HSA-70326 CO689_RS03395 676921937e6d8326bb2ad8cc094a59cf 137 Pfam PF00699 Urease beta subunit 3 101 3.6E-43 T 28-03-2018 IPR002019 Urease, beta subunit KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CO689_RS03395 676921937e6d8326bb2ad8cc094a59cf 137 SUPERFAMILY SSF51278 1 122 4.32E-47 T 28-03-2018 IPR002019 Urease, beta subunit KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CO689_RS03395 676921937e6d8326bb2ad8cc094a59cf 137 Gene3D G3DSA:2.10.150.10 1 103 7.0E-44 T 28-03-2018 IPR002019 Urease, beta subunit KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CO689_RS03395 676921937e6d8326bb2ad8cc094a59cf 137 Hamap MF_01954 Urease subunit beta [ureB]. 1 103 30.868 T 28-03-2018 IPR002019 Urease, beta subunit KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CO689_RS03395 676921937e6d8326bb2ad8cc094a59cf 137 TIGRFAM TIGR00192 urease_beta: urease, beta subunit 1 105 8.4E-46 T 28-03-2018 IPR002019 Urease, beta subunit KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CO689_RS06320 013160cedc82d9fb780fd0ad20e4c259 322 SUPERFAMILY SSF48179 181 263 2.47E-13 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CO689_RS06320 013160cedc82d9fb780fd0ad20e4c259 322 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 181 252 1.4E-11 T 28-03-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 CO689_RS06320 013160cedc82d9fb780fd0ad20e4c259 322 Gene3D G3DSA:1.10.1040.10 181 281 2.7E-15 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CO689_RS06320 013160cedc82d9fb780fd0ad20e4c259 322 Hamap MF_02129 L-carnitine dehydrogenase [lcdH]. 1 310 52.771 T 28-03-2018 IPR026578 L-carnitine dehydrogenase KEGG: 00040+1.1.1.10|MetaCyc: PWY-3602|MetaCyc: PWY-5515|MetaCyc: PWY-5525|MetaCyc: PWY-7472 CO689_RS06320 013160cedc82d9fb780fd0ad20e4c259 322 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3 176 2.3E-45 T 28-03-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 CO689_RS06320 013160cedc82d9fb780fd0ad20e4c259 322 Gene3D G3DSA:3.40.50.720 1 178 1.4E-39 T 28-03-2018 CO689_RS06320 013160cedc82d9fb780fd0ad20e4c259 322 SUPERFAMILY SSF51735 2 178 1.91E-47 T 28-03-2018 IPR016040 NAD(P)-binding domain CO689_RS10680 97780949cbf28a98953b1ed8f778fdf7 200 Pfam PF00510 Cytochrome c oxidase subunit III 18 195 2.8E-13 T 28-03-2018 IPR000298 Cytochrome c oxidase-like subunit III GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CO689_RS10680 97780949cbf28a98953b1ed8f778fdf7 200 Gene3D G3DSA:1.20.120.80 11 197 6.1E-48 T 28-03-2018 IPR013833 Cytochrome c oxidase, subunit III, 4-helical bundle GO:0004129|GO:0016020|GO:0022904 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CO689_RS10680 97780949cbf28a98953b1ed8f778fdf7 200 TIGRFAM TIGR02897 QoxC: cytochrome aa3 quinol oxidase, subunit III 8 197 8.5E-99 T 28-03-2018 IPR014246 Quinol oxidase subunit III GO:0015002|GO:0016021|GO:0042773 CO689_RS10680 97780949cbf28a98953b1ed8f778fdf7 200 SUPERFAMILY SSF81452 13 195 1.7E-50 T 28-03-2018 IPR000298 Cytochrome c oxidase-like subunit III GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CO689_RS05455 dd88553c43e6c0c7472fa49d4ecf5a5c 644 Pfam PF00199 Catalase 2 386 3.7E-177 T 28-03-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CO689_RS05455 dd88553c43e6c0c7472fa49d4ecf5a5c 644 PRINTS PR00067 Catalase signature 78 96 5.2E-66 T 28-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CO689_RS05455 dd88553c43e6c0c7472fa49d4ecf5a5c 644 PRINTS PR00067 Catalase signature 99 116 5.2E-66 T 28-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CO689_RS05455 dd88553c43e6c0c7472fa49d4ecf5a5c 644 PRINTS PR00067 Catalase signature 118 136 5.2E-66 T 28-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CO689_RS05455 dd88553c43e6c0c7472fa49d4ecf5a5c 644 PRINTS PR00067 Catalase signature 319 345 5.2E-66 T 28-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CO689_RS05455 dd88553c43e6c0c7472fa49d4ecf5a5c 644 PRINTS PR00067 Catalase signature 15 38 5.2E-66 T 28-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CO689_RS05455 dd88553c43e6c0c7472fa49d4ecf5a5c 644 PRINTS PR00067 Catalase signature 287 314 5.2E-66 T 28-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CO689_RS05455 dd88553c43e6c0c7472fa49d4ecf5a5c 644 ProSitePatterns PS00437 Catalase proximal heme-ligand signature. 332 340 - T 28-03-2018 IPR002226 Catalase haem-binding site GO:0020037 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CO689_RS05455 dd88553c43e6c0c7472fa49d4ecf5a5c 644 Gene3D G3DSA:2.40.180.10 1 357 4.7E-160 T 28-03-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CO689_RS05455 dd88553c43e6c0c7472fa49d4ecf5a5c 644 SUPERFAMILY SSF56634 1 497 1.44E-209 T 28-03-2018 IPR020835 Catalase-like domain GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CO689_RS05455 dd88553c43e6c0c7472fa49d4ecf5a5c 644 SMART SM01060 2 390 4.3E-262 T 28-03-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CO689_RS05455 dd88553c43e6c0c7472fa49d4ecf5a5c 644 PIRSF PIRSF038927 1 644 1.9E-287 T 28-03-2018 IPR024712 Catalase, mono-functional, haem-containing, clade 2 GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6 CO689_RS05455 dd88553c43e6c0c7472fa49d4ecf5a5c 644 Pfam PF06628 Catalase-related immune-responsive 417 480 7.8E-17 T 28-03-2018 IPR010582 Catalase immune-responsive domain KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CO689_RS05455 dd88553c43e6c0c7472fa49d4ecf5a5c 644 ProSitePatterns PS00438 Catalase proximal active site signature. 38 54 - T 28-03-2018 IPR024708 Catalase active site GO:0004096 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CO689_RS01160 229f2ae46921126a055f793e860fc0f7 238 Pfam PF00923 Transaldolase/Fructose-6-phosphate aldolase 10 228 7.9E-38 T 28-03-2018 IPR001585 Transaldolase/Fructose-6-phosphate aldolase GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-71336 CO689_RS01160 229f2ae46921126a055f793e860fc0f7 238 TIGRFAM TIGR02134 transald_staph: transaldolase 4 238 2.2E-129 T 28-03-2018 IPR011861 Transaldolase, Staphylococcus-type CO689_RS01160 229f2ae46921126a055f793e860fc0f7 238 Gene3D G3DSA:3.20.20.70 8 235 1.6E-50 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CO689_RS01160 229f2ae46921126a055f793e860fc0f7 238 SUPERFAMILY SSF51569 9 233 7.45E-50 T 28-03-2018 CO689_RS04645 82d50eee552dfda15a1f1ff87b69c0ab 454 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 152 166 - T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CO689_RS04645 82d50eee552dfda15a1f1ff87b69c0ab 454 SMART SM00878 334 443 8.5E-52 T 28-03-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CO689_RS04645 82d50eee552dfda15a1f1ff87b69c0ab 454 Gene3D G3DSA:3.40.50.20 1 122 2.8E-50 T 28-03-2018 CO689_RS04645 82d50eee552dfda15a1f1ff87b69c0ab 454 SUPERFAMILY SSF56059 82 350 2.83E-67 T 28-03-2018 CO689_RS04645 82d50eee552dfda15a1f1ff87b69c0ab 454 Gene3D G3DSA:3.30.1490.20 123 207 1.4E-23 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CO689_RS04645 82d50eee552dfda15a1f1ff87b69c0ab 454 SUPERFAMILY SSF52440 3 112 2.09E-45 T 28-03-2018 IPR016185 Pre-ATP-grasp domain CO689_RS04645 82d50eee552dfda15a1f1ff87b69c0ab 454 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 284 291 - T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CO689_RS04645 82d50eee552dfda15a1f1ff87b69c0ab 454 Pfam PF00289 Biotin carboxylase, N-terminal domain 3 109 3.4E-43 T 28-03-2018 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CO689_RS04645 82d50eee552dfda15a1f1ff87b69c0ab 454 Pfam PF02785 Biotin carboxylase C-terminal domain 334 443 9.8E-36 T 28-03-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CO689_RS04645 82d50eee552dfda15a1f1ff87b69c0ab 454 SUPERFAMILY SSF51246 329 445 1.73E-36 T 28-03-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 CO689_RS04645 82d50eee552dfda15a1f1ff87b69c0ab 454 Gene3D G3DSA:3.30.470.20 208 448 4.3E-85 T 28-03-2018 CO689_RS04645 82d50eee552dfda15a1f1ff87b69c0ab 454 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 114 314 2.0E-64 T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CO689_RS08450 e628130f9229be1c5c2714f44a2ad22b 185 Pfam PF12464 Maltose acetyltransferase 7 56 7.1E-14 T 28-03-2018 IPR024688 Maltose/galactoside acetyltransferase GO:0016407 CO689_RS08450 e628130f9229be1c5c2714f44a2ad22b 185 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 128 163 3.0E-11 T 28-03-2018 IPR001451 Hexapeptide repeat CO689_RS08450 e628130f9229be1c5c2714f44a2ad22b 185 Gene3D G3DSA:2.160.10.10 1 185 1.2E-53 T 28-03-2018 CO689_RS08450 e628130f9229be1c5c2714f44a2ad22b 185 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 137 165 - T 28-03-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 CO689_RS08450 e628130f9229be1c5c2714f44a2ad22b 185 SMART SM01266 5 57 3.6E-16 T 28-03-2018 IPR024688 Maltose/galactoside acetyltransferase GO:0016407 CO689_RS08450 e628130f9229be1c5c2714f44a2ad22b 185 SUPERFAMILY SSF51161 3 182 4.16E-51 T 28-03-2018 IPR011004 Trimeric LpxA-like CO689_RS05350 11797fff7f0d106a37198ebdfad48e6d 5307 Pfam PF07501 G5 domain 2827 2897 1.7E-7 T 28-03-2018 IPR011098 G5 domain CO689_RS05350 11797fff7f0d106a37198ebdfad48e6d 5307 Pfam PF07501 G5 domain 1375 1446 1.6E-10 T 28-03-2018 IPR011098 G5 domain CO689_RS05350 11797fff7f0d106a37198ebdfad48e6d 5307 Pfam PF07501 G5 domain 2358 2430 7.6E-8 T 28-03-2018 IPR011098 G5 domain CO689_RS05350 11797fff7f0d106a37198ebdfad48e6d 5307 Pfam PF07501 G5 domain 3576 3646 2.9E-9 T 28-03-2018 IPR011098 G5 domain CO689_RS05350 11797fff7f0d106a37198ebdfad48e6d 5307 Pfam PF07501 G5 domain 4350 4418 1.6E-4 T 28-03-2018 IPR011098 G5 domain CO689_RS05350 11797fff7f0d106a37198ebdfad48e6d 5307 Pfam PF07501 G5 domain 2686 2758 2.2E-7 T 28-03-2018 IPR011098 G5 domain CO689_RS05350 11797fff7f0d106a37198ebdfad48e6d 5307 Pfam PF07501 G5 domain 4888 4959 2.9E-10 T 28-03-2018 IPR011098 G5 domain CO689_RS05350 11797fff7f0d106a37198ebdfad48e6d 5307 Pfam PF07501 G5 domain 3763 3835 7.5E-12 T 28-03-2018 IPR011098 G5 domain CO689_RS05350 11797fff7f0d106a37198ebdfad48e6d 5307 Pfam PF07501 G5 domain 4419 4490 1.5E-8 T 28-03-2018 IPR011098 G5 domain CO689_RS05350 11797fff7f0d106a37198ebdfad48e6d 5307 Pfam PF07501 G5 domain 4560 4631 1.8E-8 T 28-03-2018 IPR011098 G5 domain CO689_RS05350 11797fff7f0d106a37198ebdfad48e6d 5307 Pfam PF07501 G5 domain 1703 1774 8.3E-6 T 28-03-2018 IPR011098 G5 domain CO689_RS05350 11797fff7f0d106a37198ebdfad48e6d 5307 Pfam PF07501 G5 domain 2898 2969 1.3E-7 T 28-03-2018 IPR011098 G5 domain CO689_RS05350 11797fff7f0d106a37198ebdfad48e6d 5307 Pfam PF07501 G5 domain 4747 4818 3.2E-9 T 28-03-2018 IPR011098 G5 domain CO689_RS05350 11797fff7f0d106a37198ebdfad48e6d 5307 Pfam PF07501 G5 domain 1843 1913 1.9E-10 T 28-03-2018 IPR011098 G5 domain CO689_RS05350 11797fff7f0d106a37198ebdfad48e6d 5307 Pfam PF07501 G5 domain 4091 4162 1.1E-7 T 28-03-2018 IPR011098 G5 domain CO689_RS05350 11797fff7f0d106a37198ebdfad48e6d 5307 Pfam PF07501 G5 domain 1046 1118 3.3E-10 T 28-03-2018 IPR011098 G5 domain CO689_RS05350 11797fff7f0d106a37198ebdfad48e6d 5307 Pfam PF07501 G5 domain 5005 5078 6.0E-8 T 28-03-2018 IPR011098 G5 domain CO689_RS05350 11797fff7f0d106a37198ebdfad48e6d 5307 Pfam PF07501 G5 domain 3904 3974 7.6E-8 T 28-03-2018 IPR011098 G5 domain CO689_RS05350 11797fff7f0d106a37198ebdfad48e6d 5307 Pfam PF07501 G5 domain 4676 4746 1.2E-5 T 28-03-2018 IPR011098 G5 domain CO689_RS05350 11797fff7f0d106a37198ebdfad48e6d 5307 Pfam PF07501 G5 domain 3436 3506 2.2E-8 T 28-03-2018 IPR011098 G5 domain CO689_RS05350 11797fff7f0d106a37198ebdfad48e6d 5307 Pfam PF07501 G5 domain 4232 4302 2.8E-8 T 28-03-2018 IPR011098 G5 domain CO689_RS05350 11797fff7f0d106a37198ebdfad48e6d 5307 Pfam PF07501 G5 domain 3107 3179 7.6E-8 T 28-03-2018 IPR011098 G5 domain CO689_RS05350 11797fff7f0d106a37198ebdfad48e6d 5307 Pfam PF07501 G5 domain 2499 2569 9.7E-10 T 28-03-2018 IPR011098 G5 domain CO689_RS05350 11797fff7f0d106a37198ebdfad48e6d 5307 Pfam PF07501 G5 domain 2030 2102 5.4E-9 T 28-03-2018 IPR011098 G5 domain CO689_RS05350 11797fff7f0d106a37198ebdfad48e6d 5307 Pfam PF07501 G5 domain 1187 1257 3.4E-6 T 28-03-2018 IPR011098 G5 domain CO689_RS05350 11797fff7f0d106a37198ebdfad48e6d 5307 Pfam PF07501 G5 domain 2171 2241 1.6E-7 T 28-03-2018 IPR011098 G5 domain CO689_RS05350 11797fff7f0d106a37198ebdfad48e6d 5307 Pfam PF07501 G5 domain 1517 1585 1.1E-7 T 28-03-2018 IPR011098 G5 domain CO689_RS05350 11797fff7f0d106a37198ebdfad48e6d 5307 Pfam PF07501 G5 domain 3249 3318 1.1E-7 T 28-03-2018 IPR011098 G5 domain CO689_RS05350 11797fff7f0d106a37198ebdfad48e6d 5307 SMART SM01208 4494 4558 0.83 T 28-03-2018 IPR011098 G5 domain CO689_RS05350 11797fff7f0d106a37198ebdfad48e6d 5307 SMART SM01208 1704 1776 1.6E-7 T 28-03-2018 IPR011098 G5 domain CO689_RS05350 11797fff7f0d106a37198ebdfad48e6d 5307 SMART SM01208 2353 2432 1.8E-10 T 28-03-2018 IPR011098 G5 domain CO689_RS05350 11797fff7f0d106a37198ebdfad48e6d 5307 SMART SM01208 3575 3649 1.1E-8 T 28-03-2018 IPR011098 G5 domain CO689_RS05350 11797fff7f0d106a37198ebdfad48e6d 5307 SMART SM01208 3359 3436 0.26 T 28-03-2018 IPR011098 G5 domain CO689_RS05350 11797fff7f0d106a37198ebdfad48e6d 5307 SMART SM01208 1298 1375 1.0 T 28-03-2018 IPR011098 G5 domain CO689_RS05350 11797fff7f0d106a37198ebdfad48e6d 5307 SMART SM01208 4749 4821 2.7E-9 T 28-03-2018 IPR011098 G5 domain CO689_RS05350 11797fff7f0d106a37198ebdfad48e6d 5307 SMART SM01208 2610 2687 0.32 T 28-03-2018 IPR011098 G5 domain CO689_RS05350 11797fff7f0d106a37198ebdfad48e6d 5307 SMART SM01208 1181 1260 1.1E-4 T 28-03-2018 IPR011098 G5 domain CO689_RS05350 11797fff7f0d106a37198ebdfad48e6d 5307 SMART SM01208 3897 3977 5.1E-9 T 28-03-2018 IPR011098 G5 domain CO689_RS05350 11797fff7f0d106a37198ebdfad48e6d 5307 SMART SM01208 2820 2898 9.2E-6 T 28-03-2018 IPR011098 G5 domain CO689_RS05350 11797fff7f0d106a37198ebdfad48e6d 5307 SMART SM01208 3687 3764 0.093 T 28-03-2018 IPR011098 G5 domain CO689_RS05350 11797fff7f0d106a37198ebdfad48e6d 5307 SMART SM01208 4343 4420 0.031 T 28-03-2018 IPR011098 G5 domain CO689_RS05350 11797fff7f0d106a37198ebdfad48e6d 5307 SMART SM01208 1626 1703 0.14 T 28-03-2018 IPR011098 G5 domain CO689_RS05350 11797fff7f0d106a37198ebdfad48e6d 5307 SMART SM01208 2688 2760 2.0E-7 T 28-03-2018 IPR011098 G5 domain CO689_RS05350 11797fff7f0d106a37198ebdfad48e6d 5307 SMART SM01208 3437 3509 9.2E-8 T 28-03-2018 IPR011098 G5 domain CO689_RS05350 11797fff7f0d106a37198ebdfad48e6d 5307 SMART SM01208 4822 4888 0.31 T 28-03-2018 IPR011098 G5 domain CO689_RS05350 11797fff7f0d106a37198ebdfad48e6d 5307 SMART SM01208 3109 3181 5.6E-8 T 28-03-2018 IPR011098 G5 domain CO689_RS05350 11797fff7f0d106a37198ebdfad48e6d 5307 SMART SM01208 4093 4165 2.5E-6 T 28-03-2018 IPR011098 G5 domain CO689_RS05350 11797fff7f0d106a37198ebdfad48e6d 5307 SMART SM01208 2164 2244 1.0E-7 T 28-03-2018 IPR011098 G5 domain CO689_RS05350 11797fff7f0d106a37198ebdfad48e6d 5307 SMART SM01208 977 1047 0.04 T 28-03-2018 IPR011098 G5 domain CO689_RS05350 11797fff7f0d106a37198ebdfad48e6d 5307 SMART SM01208 3030 3108 0.02 T 28-03-2018 IPR011098 G5 domain CO689_RS05350 11797fff7f0d106a37198ebdfad48e6d 5307 SMART SM01208 2899 2971 1.9E-7 T 28-03-2018 IPR011098 G5 domain CO689_RS05350 11797fff7f0d106a37198ebdfad48e6d 5307 SMART SM01208 4015 4092 0.1 T 28-03-2018 IPR011098 G5 domain CO689_RS05350 11797fff7f0d106a37198ebdfad48e6d 5307 SMART SM01208 4421 4493 2.4E-7 T 28-03-2018 IPR011098 G5 domain CO689_RS05350 11797fff7f0d106a37198ebdfad48e6d 5307 SMART SM01208 1842 1916 2.9E-10 T 28-03-2018 IPR011098 G5 domain CO689_RS05350 11797fff7f0d106a37198ebdfad48e6d 5307 SMART SM01208 905 976 0.7 T 28-03-2018 IPR011098 G5 domain CO689_RS05350 11797fff7f0d106a37198ebdfad48e6d 5307 SMART SM01208 4671 4748 0.008 T 28-03-2018 IPR011098 G5 domain CO689_RS05350 11797fff7f0d106a37198ebdfad48e6d 5307 SMART SM01208 1953 2031 0.19 T 28-03-2018 IPR011098 G5 domain CO689_RS05350 11797fff7f0d106a37198ebdfad48e6d 5307 SMART SM01208 1376 1448 5.8E-12 T 28-03-2018 IPR011098 G5 domain CO689_RS05350 11797fff7f0d106a37198ebdfad48e6d 5307 SMART SM01208 4889 4962 6.9E-10 T 28-03-2018 IPR011098 G5 domain CO689_RS05350 11797fff7f0d106a37198ebdfad48e6d 5307 SMART SM01208 4231 4305 2.8E-8 T 28-03-2018 IPR011098 G5 domain CO689_RS05350 11797fff7f0d106a37198ebdfad48e6d 5307 SMART SM01208 3765 3837 4.0E-13 T 28-03-2018 IPR011098 G5 domain CO689_RS05350 11797fff7f0d106a37198ebdfad48e6d 5307 SMART SM01208 2498 2572 3.1E-8 T 28-03-2018 IPR011098 G5 domain CO689_RS05350 11797fff7f0d106a37198ebdfad48e6d 5307 SMART SM01208 3241 3321 6.6E-7 T 28-03-2018 IPR011098 G5 domain CO689_RS05350 11797fff7f0d106a37198ebdfad48e6d 5307 SMART SM01208 1514 1588 8.4E-6 T 28-03-2018 IPR011098 G5 domain CO689_RS05350 11797fff7f0d106a37198ebdfad48e6d 5307 SMART SM01208 1048 1120 3.4E-11 T 28-03-2018 IPR011098 G5 domain CO689_RS05350 11797fff7f0d106a37198ebdfad48e6d 5307 SMART SM01208 2032 2104 1.3E-9 T 28-03-2018 IPR011098 G5 domain CO689_RS05350 11797fff7f0d106a37198ebdfad48e6d 5307 SMART SM01208 5002 5080 2.6E-10 T 28-03-2018 IPR011098 G5 domain CO689_RS05350 11797fff7f0d106a37198ebdfad48e6d 5307 SMART SM01208 4559 4633 2.2E-8 T 28-03-2018 IPR011098 G5 domain CO689_RS05350 11797fff7f0d106a37198ebdfad48e6d 5307 TIGRFAM TIGR01168 YSIRK_signal: gram-positive signal peptide, YSIRK family 4 45 4.7E-12 T 28-03-2018 IPR005877 YSIRK Gram-positive signal peptide GO:0016020 CO689_RS05350 11797fff7f0d106a37198ebdfad48e6d 5307 Gene3D G3DSA:2.20.230.10 3246 3317 3.4E-13 T 28-03-2018 CO689_RS05350 11797fff7f0d106a37198ebdfad48e6d 5307 Gene3D G3DSA:2.20.230.10 3432 3505 1.4E-13 T 28-03-2018 CO689_RS05350 11797fff7f0d106a37198ebdfad48e6d 5307 Gene3D G3DSA:2.20.230.10 2496 2568 2.9E-15 T 28-03-2018 CO689_RS05350 11797fff7f0d106a37198ebdfad48e6d 5307 Gene3D G3DSA:2.20.230.10 1185 1256 5.4E-11 T 28-03-2018 CO689_RS05350 11797fff7f0d106a37198ebdfad48e6d 5307 Gene3D G3DSA:2.20.230.10 3358 3431 5.6E-5 T 28-03-2018 CO689_RS05350 11797fff7f0d106a37198ebdfad48e6d 5307 Gene3D G3DSA:2.20.230.10 4746 4817 1.4E-17 T 28-03-2018 CO689_RS05350 11797fff7f0d106a37198ebdfad48e6d 5307 Gene3D G3DSA:2.20.230.10 2689 2756 7.4E-14 T 28-03-2018 CO689_RS05350 11797fff7f0d106a37198ebdfad48e6d 5307 Gene3D G3DSA:2.20.230.10 3900 3973 8.4E-14 T 28-03-2018 CO689_RS05350 11797fff7f0d106a37198ebdfad48e6d 5307 Gene3D G3DSA:2.20.230.10 1513 1584 9.8E-12 T 28-03-2018 CO689_RS05350 11797fff7f0d106a37198ebdfad48e6d 5307 Gene3D G3DSA:2.20.230.10 4558 4629 7.7E-14 T 28-03-2018 CO689_RS05350 11797fff7f0d106a37198ebdfad48e6d 5307 Gene3D G3DSA:2.20.230.10 4885 4958 7.2E-16 T 28-03-2018 CO689_RS05350 11797fff7f0d106a37198ebdfad48e6d 5307 Gene3D G3DSA:2.20.230.10 1044 1116 5.4E-16 T 28-03-2018 CO689_RS05350 11797fff7f0d106a37198ebdfad48e6d 5307 Gene3D G3DSA:2.20.230.10 1302 1371 1.5E-4 T 28-03-2018 CO689_RS05350 11797fff7f0d106a37198ebdfad48e6d 5307 Gene3D G3DSA:2.20.230.10 2027 2100 1.8E-15 T 28-03-2018 CO689_RS05350 11797fff7f0d106a37198ebdfad48e6d 5307 Gene3D G3DSA:2.20.230.10 974 1043 1.1E-6 T 28-03-2018 CO689_RS05350 11797fff7f0d106a37198ebdfad48e6d 5307 Gene3D G3DSA:2.20.230.10 4091 4161 1.9E-14 T 28-03-2018 CO689_RS05350 11797fff7f0d106a37198ebdfad48e6d 5307 Gene3D G3DSA:2.20.230.10 907 973 0.013 T 28-03-2018 CO689_RS05350 11797fff7f0d106a37198ebdfad48e6d 5307 Gene3D G3DSA:2.20.230.10 1626 1699 1.6E-5 T 28-03-2018 CO689_RS05350 11797fff7f0d106a37198ebdfad48e6d 5307 Gene3D G3DSA:2.20.230.10 1840 1912 3.2E-14 T 28-03-2018 CO689_RS05350 11797fff7f0d106a37198ebdfad48e6d 5307 Gene3D G3DSA:2.20.230.10 4633 4659 0.023 T 28-03-2018 CO689_RS05350 11797fff7f0d106a37198ebdfad48e6d 5307 Gene3D G3DSA:2.20.230.10 2897 2967 3.0E-14 T 28-03-2018 CO689_RS05350 11797fff7f0d106a37198ebdfad48e6d 5307 Gene3D G3DSA:2.20.230.10 2168 2240 7.2E-13 T 28-03-2018 CO689_RS05350 11797fff7f0d106a37198ebdfad48e6d 5307 Gene3D G3DSA:2.20.230.10 3034 3104 1.5E-7 T 28-03-2018 CO689_RS05350 11797fff7f0d106a37198ebdfad48e6d 5307 Gene3D G3DSA:2.20.230.10 3319 3347 0.18 T 28-03-2018 CO689_RS05350 11797fff7f0d106a37198ebdfad48e6d 5307 Gene3D G3DSA:2.20.230.10 1953 2026 9.0E-5 T 28-03-2018 CO689_RS05350 11797fff7f0d106a37198ebdfad48e6d 5307 Gene3D G3DSA:2.20.230.10 4229 4301 3.4E-14 T 28-03-2018 CO689_RS05350 11797fff7f0d106a37198ebdfad48e6d 5307 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 5270 5302 0.0014 T 28-03-2018 CO689_RS05350 11797fff7f0d106a37198ebdfad48e6d 5307 Pfam PF04650 YSIRK type signal peptide 9 34 2.3E-11 T 28-03-2018 IPR005877 YSIRK Gram-positive signal peptide GO:0016020 CO689_RS05350 11797fff7f0d106a37198ebdfad48e6d 5307 Gene3D G3DSA:2.20.230.10 4495 4557 2.3E-5 T 28-03-2018 CO689_RS05350 11797fff7f0d106a37198ebdfad48e6d 5307 Gene3D G3DSA:2.20.230.10 1373 1447 8.2E-16 T 28-03-2018 CO689_RS05350 11797fff7f0d106a37198ebdfad48e6d 5307 Gene3D G3DSA:2.20.230.10 3106 3179 2.3E-13 T 28-03-2018 CO689_RS05350 11797fff7f0d106a37198ebdfad48e6d 5307 Gene3D G3DSA:2.20.230.10 3839 3899 3.7E-4 T 28-03-2018 CO689_RS05350 11797fff7f0d106a37198ebdfad48e6d 5307 Gene3D G3DSA:2.20.230.10 4345 4419 4.3E-5 T 28-03-2018 CO689_RS05350 11797fff7f0d106a37198ebdfad48e6d 5307 Gene3D G3DSA:2.20.230.10 2361 2430 4.8E-14 T 28-03-2018 CO689_RS05350 11797fff7f0d106a37198ebdfad48e6d 5307 Gene3D G3DSA:2.20.230.10 2570 2598 0.52 T 28-03-2018 CO689_RS05350 11797fff7f0d106a37198ebdfad48e6d 5307 Gene3D G3DSA:2.20.230.10 4820 4884 3.3E-6 T 28-03-2018 CO689_RS05350 11797fff7f0d106a37198ebdfad48e6d 5307 Gene3D G3DSA:2.20.230.10 3689 3763 2.9E-6 T 28-03-2018 CO689_RS05350 11797fff7f0d106a37198ebdfad48e6d 5307 Gene3D G3DSA:2.20.230.10 4960 4989 0.018 T 28-03-2018 CO689_RS05350 11797fff7f0d106a37198ebdfad48e6d 5307 Gene3D G3DSA:2.20.230.10 2825 2896 6.3E-11 T 28-03-2018 CO689_RS05350 11797fff7f0d106a37198ebdfad48e6d 5307 Gene3D G3DSA:2.20.230.10 3574 3649 1.5E-13 T 28-03-2018 CO689_RS05350 11797fff7f0d106a37198ebdfad48e6d 5307 Gene3D G3DSA:2.20.230.10 1118 1184 1.5E-4 T 28-03-2018 CO689_RS05350 11797fff7f0d106a37198ebdfad48e6d 5307 Gene3D G3DSA:2.20.230.10 2969 3033 2.4E-4 T 28-03-2018 CO689_RS05350 11797fff7f0d106a37198ebdfad48e6d 5307 Gene3D G3DSA:2.20.230.10 2758 2824 6.2E-5 T 28-03-2018 CO689_RS05350 11797fff7f0d106a37198ebdfad48e6d 5307 Gene3D G3DSA:2.20.230.10 2102 2167 0.013 T 28-03-2018 CO689_RS05350 11797fff7f0d106a37198ebdfad48e6d 5307 Gene3D G3DSA:2.20.230.10 2431 2495 8.5E-4 T 28-03-2018 CO689_RS05350 11797fff7f0d106a37198ebdfad48e6d 5307 Gene3D G3DSA:2.20.230.10 1448 1512 6.6E-4 T 28-03-2018 CO689_RS05350 11797fff7f0d106a37198ebdfad48e6d 5307 Gene3D G3DSA:2.20.230.10 4672 4745 2.4E-7 T 28-03-2018 CO689_RS05350 11797fff7f0d106a37198ebdfad48e6d 5307 Gene3D G3DSA:2.20.230.10 1775 1839 2.0E-5 T 28-03-2018 CO689_RS05350 11797fff7f0d106a37198ebdfad48e6d 5307 Gene3D G3DSA:2.20.230.10 4164 4228 4.5E-7 T 28-03-2018 CO689_RS05350 11797fff7f0d106a37198ebdfad48e6d 5307 Gene3D G3DSA:2.20.230.10 1701 1774 9.3E-14 T 28-03-2018 CO689_RS05350 11797fff7f0d106a37198ebdfad48e6d 5307 Gene3D G3DSA:2.20.230.10 4016 4090 2.2E-6 T 28-03-2018 CO689_RS05350 11797fff7f0d106a37198ebdfad48e6d 5307 Gene3D G3DSA:2.20.230.10 3508 3573 3.0E-5 T 28-03-2018 CO689_RS05350 11797fff7f0d106a37198ebdfad48e6d 5307 Gene3D G3DSA:2.20.230.10 3180 3245 3.2E-4 T 28-03-2018 CO689_RS05350 11797fff7f0d106a37198ebdfad48e6d 5307 Gene3D G3DSA:2.20.230.10 3764 3838 2.2E-15 T 28-03-2018 CO689_RS05350 11797fff7f0d106a37198ebdfad48e6d 5307 Gene3D G3DSA:2.20.230.10 2278 2360 0.0043 T 28-03-2018 CO689_RS05350 11797fff7f0d106a37198ebdfad48e6d 5307 Gene3D G3DSA:2.20.230.10 5003 5085 6.1E-15 T 28-03-2018 CO689_RS05350 11797fff7f0d106a37198ebdfad48e6d 5307 Gene3D G3DSA:2.20.230.10 2609 2688 1.2E-6 T 28-03-2018 CO689_RS05350 11797fff7f0d106a37198ebdfad48e6d 5307 Gene3D G3DSA:2.20.230.10 4420 4494 1.5E-15 T 28-03-2018 CO689_RS05350 11797fff7f0d106a37198ebdfad48e6d 5307 Pfam PF00746 LPXTG cell wall anchor motif 5263 5304 1.4E-5 T 28-03-2018 IPR019948 Gram-positive LPXTG cell wall anchor CO689_RS01620 a215c6eff1438bbf1567485df9e13193 429 TIGRFAM TIGR00713 hemL: glutamate-1-semialdehyde-2,1-aminomutase 11 427 1.8E-168 T 28-03-2018 IPR004639 Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase GO:0033014|GO:0042286 KEGG: 00860+5.4.3.8|MetaCyc: PWY-5188 CO689_RS01620 a215c6eff1438bbf1567485df9e13193 429 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 237 273 - T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CO689_RS01620 a215c6eff1438bbf1567485df9e13193 429 SUPERFAMILY SSF53383 3 427 1.92E-123 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CO689_RS01620 a215c6eff1438bbf1567485df9e13193 429 Pfam PF00202 Aminotransferase class-III 35 415 9.0E-74 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CO689_RS01620 a215c6eff1438bbf1567485df9e13193 429 Gene3D G3DSA:3.40.640.10 173 314 6.2E-36 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CO689_RS01620 a215c6eff1438bbf1567485df9e13193 429 Gene3D G3DSA:3.90.1150.10 1 172 3.6E-42 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CO689_RS01620 a215c6eff1438bbf1567485df9e13193 429 Gene3D G3DSA:3.90.1150.10 315 429 9.4E-18 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CO689_RS01620 a215c6eff1438bbf1567485df9e13193 429 Hamap MF_00375 Glutamate-1-semialdehyde 2,1-aminomutase [hemL]. 5 428 90.299 T 28-03-2018 IPR004639 Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase GO:0033014|GO:0042286 KEGG: 00860+5.4.3.8|MetaCyc: PWY-5188 CO689_RS11015 d55b56a5ff49976c5f4102045cb897d6 161 Hamap MF_00151 Phosphopantetheine adenylyltransferase [coaD]. 4 160 34.986 T 28-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 CO689_RS11015 d55b56a5ff49976c5f4102045cb897d6 161 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 6 65 7.6E-15 T 28-03-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 CO689_RS11015 d55b56a5ff49976c5f4102045cb897d6 161 Pfam PF01467 Cytidylyltransferase-like 8 135 3.2E-18 T 28-03-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 CO689_RS11015 d55b56a5ff49976c5f4102045cb897d6 161 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 51 75 5.5E-50 T 28-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 CO689_RS11015 d55b56a5ff49976c5f4102045cb897d6 161 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 87 103 5.5E-50 T 28-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 CO689_RS11015 d55b56a5ff49976c5f4102045cb897d6 161 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 22 43 5.5E-50 T 28-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 CO689_RS11015 d55b56a5ff49976c5f4102045cb897d6 161 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 114 136 5.5E-50 T 28-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 CO689_RS11015 d55b56a5ff49976c5f4102045cb897d6 161 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 4 22 5.5E-50 T 28-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 CO689_RS11015 d55b56a5ff49976c5f4102045cb897d6 161 TIGRFAM TIGR01510 coaD_prev_kdtB: pantetheine-phosphate adenylyltransferase 6 159 5.6E-59 T 28-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 CO689_RS11015 d55b56a5ff49976c5f4102045cb897d6 161 ProDom PD016147 LIGASE LYASE CITRATE PRO-3S-LYASE SYNTHETASE TRANSFERASE CYTIDYLTRANSFERASE-RELATED:CITRATE ACETATE:SH-CITRATE CITC PLASMID 13 76 2.0E-4 T 28-03-2018 CO689_RS11015 d55b56a5ff49976c5f4102045cb897d6 161 SUPERFAMILY SSF52374 5 158 3.38E-42 T 28-03-2018 CO689_RS11015 d55b56a5ff49976c5f4102045cb897d6 161 Gene3D G3DSA:3.40.50.620 2 160 1.2E-35 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CO689_RS06035 6a6ede6abce78c3f560b50772533d248 318 Gene3D G3DSA:1.10.150.130 2 134 0.0043 T 28-03-2018 IPR023109 Integrase/recombinase, N-terminal CO689_RS06035 6a6ede6abce78c3f560b50772533d248 318 Pfam PF13280 WYL domain 143 314 3.5E-21 T 28-03-2018 IPR026881 WYL domain CO689_RS06120 f43f18a2526b7ec5da2d7e0b0be97fc6 137 Gene3D G3DSA:3.40.1440.10 26 134 3.9E-12 T 28-03-2018 IPR000305 GIY-YIG nuclease superfamily CO689_RS06120 f43f18a2526b7ec5da2d7e0b0be97fc6 137 SUPERFAMILY SSF82771 40 124 1.44E-6 T 28-03-2018 IPR000305 GIY-YIG nuclease superfamily CO689_RS10715 6b409e898a6128a6cb77dbd9afaae1cc 160 Pfam PF00731 AIR carboxylase 2 148 1.7E-65 T 28-03-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 CO689_RS10715 6b409e898a6128a6cb77dbd9afaae1cc 160 PIRSF PIRSF001338 1 160 5.5E-70 T 28-03-2018 IPR024694 PurE, prokaryotic type GO:0006189 KEGG: 00230+5.4.99.18|MetaCyc: PWY-6123|MetaCyc: PWY-7234 CO689_RS10715 6b409e898a6128a6cb77dbd9afaae1cc 160 SUPERFAMILY SSF52255 2 159 1.16E-65 T 28-03-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 CO689_RS10715 6b409e898a6128a6cb77dbd9afaae1cc 160 SMART SM01001 1 152 1.7E-101 T 28-03-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 CO689_RS10715 6b409e898a6128a6cb77dbd9afaae1cc 160 Gene3D G3DSA:3.40.50.7700 1 160 1.5E-67 T 28-03-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 CO689_RS10715 6b409e898a6128a6cb77dbd9afaae1cc 160 TIGRFAM TIGR01162 purE: phosphoribosylaminoimidazole carboxylase, catalytic subunit 3 159 1.7E-65 T 28-03-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 CO689_RS10715 6b409e898a6128a6cb77dbd9afaae1cc 160 Hamap MF_01929 N5-carboxyaminoimidazole ribonucleotide mutase [purE]. 3 156 32.293 T 28-03-2018 IPR033747 Class I PurE CO689_RS01065 762ee5a5a7d1b7d1ab4bd27e44d4b453 418 Gene3D G3DSA:3.50.50.60 2 416 3.9E-52 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CO689_RS01065 762ee5a5a7d1b7d1ab4bd27e44d4b453 418 SUPERFAMILY SSF51905 4 193 6.11E-51 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CO689_RS01065 762ee5a5a7d1b7d1ab4bd27e44d4b453 418 SUPERFAMILY SSF51905 357 414 6.11E-51 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CO689_RS01065 762ee5a5a7d1b7d1ab4bd27e44d4b453 418 TIGRFAM TIGR00275 TIGR00275: flavoprotein, HI0933 family 5 411 2.4E-141 T 28-03-2018 IPR004792 Conserved hypothetical protein CHP00275, flavoprotein HI0933-like CO689_RS01065 762ee5a5a7d1b7d1ab4bd27e44d4b453 418 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 367 389 2.9E-7 T 28-03-2018 CO689_RS01065 762ee5a5a7d1b7d1ab4bd27e44d4b453 418 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 4 23 2.9E-7 T 28-03-2018 CO689_RS01065 762ee5a5a7d1b7d1ab4bd27e44d4b453 418 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 155 173 2.9E-7 T 28-03-2018 CO689_RS01065 762ee5a5a7d1b7d1ab4bd27e44d4b453 418 SUPERFAMILY SSF160996 192 360 9.16E-47 T 28-03-2018 CO689_RS01065 762ee5a5a7d1b7d1ab4bd27e44d4b453 418 Pfam PF03486 HI0933-like protein 3 411 5.0E-152 T 28-03-2018 CO689_RS06910 f66bbd623602c29d3e7783e0093568fa 266 Pfam PF12706 Beta-lactamase superfamily domain 28 220 8.6E-22 T 28-03-2018 IPR001279 Metallo-beta-lactamase CO689_RS06910 f66bbd623602c29d3e7783e0093568fa 266 Gene3D G3DSA:3.60.15.10 9 254 1.1E-34 T 28-03-2018 IPR001279 Metallo-beta-lactamase CO689_RS06910 f66bbd623602c29d3e7783e0093568fa 266 SUPERFAMILY SSF56281 11 234 8.65E-41 T 28-03-2018 IPR001279 Metallo-beta-lactamase CO689_RS06910 f66bbd623602c29d3e7783e0093568fa 266 SMART SM00849 15 220 6.0E-11 T 28-03-2018 IPR001279 Metallo-beta-lactamase CO689_RS04850 3e8693ceb4dab2dee8cfbb7fc6a103b4 597 Pfam PF00149 Calcineurin-like phosphoesterase 225 439 3.6E-19 T 28-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 CO689_RS04850 3e8693ceb4dab2dee8cfbb7fc6a103b4 597 SUPERFAMILY SSF56300 224 494 2.15E-42 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CO689_RS04850 3e8693ceb4dab2dee8cfbb7fc6a103b4 597 SUPERFAMILY SSF49363 180 217 3.4E-7 T 28-03-2018 IPR008963 Purple acid phosphatase-like, N-terminal GO:0003993|GO:0046872 CO689_RS04850 3e8693ceb4dab2dee8cfbb7fc6a103b4 597 Gene3D G3DSA:3.60.21.10 222 597 3.3E-48 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CO689_RS04850 3e8693ceb4dab2dee8cfbb7fc6a103b4 597 Pfam PF16656 Purple acid Phosphatase, N-terminal domain 65 217 9.4E-20 T 28-03-2018 IPR015914 Purple acid phosphatase, N-terminal GO:0003993|GO:0046872 CO689_RS04850 3e8693ceb4dab2dee8cfbb7fc6a103b4 597 Gene3D G3DSA:2.60.40.380 64 221 2.9E-22 T 28-03-2018 CO689_RS06995 f926ae948482251372b3812b6e4e17e5 274 TIGRFAM TIGR00196 yjeF_cterm: YjeF family C-terminal domain 7 268 2.8E-53 T 28-03-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 CO689_RS06995 f926ae948482251372b3812b6e4e17e5 274 Gene3D G3DSA:3.40.1190.20 3 274 2.4E-38 T 28-03-2018 IPR029056 Ribokinase-like CO689_RS06995 f926ae948482251372b3812b6e4e17e5 274 ProSitePatterns PS01049 YjeF C-terminal domain signature 1. 91 101 - T 28-03-2018 IPR017953 Carbohydrate kinase, predicted, conserved site CO689_RS06995 f926ae948482251372b3812b6e4e17e5 274 Pfam PF01256 Carbohydrate kinase 25 263 1.2E-53 T 28-03-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 CO689_RS06995 f926ae948482251372b3812b6e4e17e5 274 Hamap MF_01965 ADP-dependent (S)-NAD(P)H-hydrate dehydratase [nnrD]. 1 271 22.643 T 28-03-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 CO689_RS06995 f926ae948482251372b3812b6e4e17e5 274 ProSitePatterns PS01050 YjeF C-terminal domain signature 2. 208 218 - T 28-03-2018 IPR017953 Carbohydrate kinase, predicted, conserved site CO689_RS06995 f926ae948482251372b3812b6e4e17e5 274 SUPERFAMILY SSF53613 7 268 2.77E-60 T 28-03-2018 IPR029056 Ribokinase-like CO689_RS12770 f28323389d82d85bbc236745c1fa14da 358 Gene3D G3DSA:3.40.50.1970 2 170 2.9E-42 T 28-03-2018 CO689_RS12770 f28323389d82d85bbc236745c1fa14da 358 TIGRFAM TIGR01357 aroB: 3-dehydroquinate synthase 12 347 2.6E-105 T 28-03-2018 IPR016037 3-dehydroquinate synthase AroB GO:0003856|GO:0005737|GO:0009073 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 CO689_RS12770 f28323389d82d85bbc236745c1fa14da 358 Hamap MF_00110 3-dehydroquinate synthase [aroB]. 1 352 34.131 T 28-03-2018 IPR016037 3-dehydroquinate synthase AroB GO:0003856|GO:0005737|GO:0009073 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 CO689_RS12770 f28323389d82d85bbc236745c1fa14da 358 Pfam PF01761 3-dehydroquinate synthase 66 320 2.6E-84 T 28-03-2018 IPR030960 3-dehydroquinate synthase domain KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 CO689_RS12770 f28323389d82d85bbc236745c1fa14da 358 SUPERFAMILY SSF56796 1 354 2.88E-86 T 28-03-2018 CO689_RS12770 f28323389d82d85bbc236745c1fa14da 358 Gene3D G3DSA:1.20.1090.10 171 358 6.7E-45 T 28-03-2018 CO689_RS12770 f28323389d82d85bbc236745c1fa14da 358 PIRSF PIRSF001455 1 358 2.7E-104 T 28-03-2018 IPR030963 3-dehydroquinate synthase family GO:0009073|GO:0016838 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 CO689_RS08690 a9460e0cf8c00fcaf408415aeaa06561 289 SUPERFAMILY SSF46785 3 111 8.17E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS08690 a9460e0cf8c00fcaf408415aeaa06561 289 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 5.6E-7 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CO689_RS08690 a9460e0cf8c00fcaf408415aeaa06561 289 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 5.6E-7 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CO689_RS08690 a9460e0cf8c00fcaf408415aeaa06561 289 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 5.6E-7 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CO689_RS08690 a9460e0cf8c00fcaf408415aeaa06561 289 Gene3D G3DSA:3.40.190.10 174 254 1.6E-5 T 28-03-2018 CO689_RS08690 a9460e0cf8c00fcaf408415aeaa06561 289 SUPERFAMILY SSF53850 88 286 9.62E-25 T 28-03-2018 CO689_RS08690 a9460e0cf8c00fcaf408415aeaa06561 289 Pfam PF03466 LysR substrate binding domain 88 280 2.1E-25 T 28-03-2018 IPR005119 LysR, substrate-binding CO689_RS08690 a9460e0cf8c00fcaf408415aeaa06561 289 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 61 3.6E-14 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CO689_RS08690 a9460e0cf8c00fcaf408415aeaa06561 289 Gene3D G3DSA:1.10.10.10 1 86 4.0E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS08690 a9460e0cf8c00fcaf408415aeaa06561 289 Gene3D G3DSA:3.40.190.10 91 173 4.7E-10 T 28-03-2018 CO689_RS10030 923387b16dfb499ed68a53ec1cebb787 201 Gene3D G3DSA:1.20.5.420 88 142 2.9E-8 T 28-03-2018 CO689_RS10030 923387b16dfb499ed68a53ec1cebb787 201 Pfam PF04650 YSIRK type signal peptide 10 34 3.8E-12 T 28-03-2018 IPR005877 YSIRK Gram-positive signal peptide GO:0016020 CO689_RS10030 923387b16dfb499ed68a53ec1cebb787 201 TIGRFAM TIGR01168 YSIRK_signal: gram-positive signal peptide, YSIRK family 8 45 7.9E-14 T 28-03-2018 IPR005877 YSIRK Gram-positive signal peptide GO:0016020 CO689_RS12550 31b6cb8242d994ef7f032abff52f5680 425 TIGRFAM TIGR01347 sucB: dihydrolipoyllysine-residue succinyltransferase, E2 component of oxoglutarate dehydrogenase (succinyl-transferring) complex 3 424 4.7E-176 T 28-03-2018 IPR006255 Dihydrolipoamide succinyltransferase GO:0004149|GO:0006099|GO:0045252 KEGG: 00020+2.3.1.61|KEGG: 00310+2.3.1.61|MetaCyc: PWY-5084|Reactome: R-HSA-389661|Reactome: R-HSA-71064|Reactome: R-HSA-71403 CO689_RS12550 31b6cb8242d994ef7f032abff52f5680 425 Gene3D G3DSA:3.90.1170.30 44 100 0.015 T 28-03-2018 CO689_RS12550 31b6cb8242d994ef7f032abff52f5680 425 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 26 55 - T 28-03-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 CO689_RS12550 31b6cb8242d994ef7f032abff52f5680 425 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 195 423 3.3E-76 T 28-03-2018 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CO689_RS12550 31b6cb8242d994ef7f032abff52f5680 425 Pfam PF02817 e3 binding domain 131 163 2.0E-7 T 28-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CO689_RS12550 31b6cb8242d994ef7f032abff52f5680 425 Gene3D G3DSA:4.10.320.10 121 182 2.5E-11 T 28-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CO689_RS12550 31b6cb8242d994ef7f032abff52f5680 425 Pfam PF00364 Biotin-requiring enzyme 3 74 1.5E-19 T 28-03-2018 IPR000089 Biotin/lipoyl attachment CO689_RS12550 31b6cb8242d994ef7f032abff52f5680 425 SUPERFAMILY SSF52777 183 423 3.2E-78 T 28-03-2018 CO689_RS12550 31b6cb8242d994ef7f032abff52f5680 425 SUPERFAMILY SSF51230 2 93 2.49E-25 T 28-03-2018 IPR011053 Single hybrid motif CO689_RS12550 31b6cb8242d994ef7f032abff52f5680 425 SUPERFAMILY SSF47005 124 165 2.62E-5 T 28-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CO689_RS12550 31b6cb8242d994ef7f032abff52f5680 425 Gene3D G3DSA:3.90.1170.30 1 43 1.3E-14 T 28-03-2018 CO689_RS12550 31b6cb8242d994ef7f032abff52f5680 425 Gene3D G3DSA:3.30.559.10 183 423 8.9E-82 T 28-03-2018 CO689_RS07525 fe5975f4cdc7821bd82744c8d2bb55b7 175 Pfam PF00583 Acetyltransferase (GNAT) family 35 132 8.5E-10 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CO689_RS07525 fe5975f4cdc7821bd82744c8d2bb55b7 175 SUPERFAMILY SSF55729 1 150 3.76E-18 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CO689_RS07525 fe5975f4cdc7821bd82744c8d2bb55b7 175 Gene3D G3DSA:3.40.630.30 2 169 1.6E-16 T 28-03-2018 CO689_RS02865 413b4fd5d03eee58d782eb76cebe5470 585 Pfam PF04183 IucA / IucC family 158 384 1.8E-49 T 28-03-2018 IPR007310 Aerobactin siderophore biosynthesis, IucA/IucC, N-terminal GO:0015343|GO:0019290 CO689_RS02865 413b4fd5d03eee58d782eb76cebe5470 585 Pfam PF06276 Ferric iron reductase FhuF-like transporter 414 568 4.7E-25 T 28-03-2018 IPR022770 Ferric iron reductase FhuF domain CO689_RS01455 fb608b7c311c907be7ee512ce8f1c6f1 352 Pfam PF13303 Phosphotransferase system, EIIC 14 343 1.8E-81 T 28-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 CO689_RS00575 dd35153193246b2f0cd15d8c94094301 585 Gene3D G3DSA:3.40.710.10 341 582 2.1E-24 T 28-03-2018 CO689_RS00575 dd35153193246b2f0cd15d8c94094301 585 SUPERFAMILY SSF56601 348 579 1.69E-29 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CO689_RS00575 dd35153193246b2f0cd15d8c94094301 585 Gene3D G3DSA:3.30.2010.10 147 219 5.7E-4 T 28-03-2018 CO689_RS00575 dd35153193246b2f0cd15d8c94094301 585 Pfam PF00905 Penicillin binding protein transpeptidase domain 362 577 1.3E-39 T 28-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 CO689_RS00575 dd35153193246b2f0cd15d8c94094301 585 Pfam PF05569 BlaR1 peptidase M56 4 298 7.3E-94 T 28-03-2018 IPR008756 Peptidase M56 CO689_RS08425 dc8a3a4387ec1a6d310c070c87492aaf 237 SMART SM00382 27 211 1.4E-13 T 28-03-2018 IPR003593 AAA+ ATPase domain CO689_RS08425 dc8a3a4387ec1a6d310c070c87492aaf 237 SUPERFAMILY SSF52540 2 216 2.28E-48 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CO689_RS08425 dc8a3a4387ec1a6d310c070c87492aaf 237 Pfam PF00005 ABC transporter 17 162 3.8E-27 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CO689_RS08425 dc8a3a4387ec1a6d310c070c87492aaf 237 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CO689_RS08425 dc8a3a4387ec1a6d310c070c87492aaf 237 Gene3D G3DSA:3.40.50.300 1 237 1.3E-51 T 28-03-2018 CO689_RS08480 937bd521bca0b3a9743a241a22dc1881 265 ProSitePatterns PS00211 ABC transporters family signature. 145 159 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CO689_RS08480 937bd521bca0b3a9743a241a22dc1881 265 SMART SM00382 50 229 9.4E-7 T 28-03-2018 IPR003593 AAA+ ATPase domain CO689_RS08480 937bd521bca0b3a9743a241a22dc1881 265 Pfam PF00005 ABC transporter 41 172 3.3E-15 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CO689_RS08480 937bd521bca0b3a9743a241a22dc1881 265 Gene3D G3DSA:3.40.50.300 2 261 4.2E-46 T 28-03-2018 CO689_RS08480 937bd521bca0b3a9743a241a22dc1881 265 SUPERFAMILY SSF52540 37 235 5.21E-41 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CO689_RS07035 2335c9d365ef63070acf2628bf875625 115 Pfam PF00825 Ribonuclease P 2 106 1.2E-30 T 28-03-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 CO689_RS07035 2335c9d365ef63070acf2628bf875625 115 Hamap MF_00227 Ribonuclease P protein component [rnpA]. 1 110 19.264 T 28-03-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 CO689_RS07035 2335c9d365ef63070acf2628bf875625 115 ProSitePatterns PS00648 Bacterial ribonuclease P protein component signature. 51 65 - T 28-03-2018 IPR020539 Ribonuclease P, conserved site GO:0004526 CO689_RS07035 2335c9d365ef63070acf2628bf875625 115 ProDom PD003629 P RIBONUCLEASE COMPONENT HYDROLASE RNASE C5 RNASEP RNA-BINDING PROCESSING ENDONUCLEASE 7 115 4.0E-45 T 28-03-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 CO689_RS07035 2335c9d365ef63070acf2628bf875625 115 Gene3D G3DSA:3.30.230.10 1 115 1.4E-30 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CO689_RS07035 2335c9d365ef63070acf2628bf875625 115 SUPERFAMILY SSF54211 2 112 7.84E-32 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CO689_RS07035 2335c9d365ef63070acf2628bf875625 115 TIGRFAM TIGR00188 rnpA: ribonuclease P protein component 3 106 6.4E-28 T 28-03-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 CO689_RS12330 b7e594102cdfbabcf9dc118b9f2381e8 207 Pfam PF00117 Glutamine amidotransferase class-I 4 180 2.0E-36 T 28-03-2018 IPR017926 Glutamine amidotransferase CO689_RS12330 b7e594102cdfbabcf9dc118b9f2381e8 207 PRINTS PR00097 Anthranilate synthase component II signature 2 16 5.0E-32 T 28-03-2018 CO689_RS12330 b7e594102cdfbabcf9dc118b9f2381e8 207 PRINTS PR00097 Anthranilate synthase component II signature 94 102 5.0E-32 T 28-03-2018 CO689_RS12330 b7e594102cdfbabcf9dc118b9f2381e8 207 PRINTS PR00097 Anthranilate synthase component II signature 43 52 5.0E-32 T 28-03-2018 CO689_RS12330 b7e594102cdfbabcf9dc118b9f2381e8 207 PRINTS PR00097 Anthranilate synthase component II signature 115 127 5.0E-32 T 28-03-2018 CO689_RS12330 b7e594102cdfbabcf9dc118b9f2381e8 207 PRINTS PR00097 Anthranilate synthase component II signature 69 80 5.0E-32 T 28-03-2018 CO689_RS12330 b7e594102cdfbabcf9dc118b9f2381e8 207 PRINTS PR00097 Anthranilate synthase component II signature 159 172 5.0E-32 T 28-03-2018 CO689_RS12330 b7e594102cdfbabcf9dc118b9f2381e8 207 Gene3D G3DSA:3.40.50.880 1 186 6.6E-43 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CO689_RS12330 b7e594102cdfbabcf9dc118b9f2381e8 207 PRINTS PR00096 Glutamine amidotransferase superfamily signature 43 52 4.3E-13 T 28-03-2018 CO689_RS12330 b7e594102cdfbabcf9dc118b9f2381e8 207 PRINTS PR00096 Glutamine amidotransferase superfamily signature 159 172 4.3E-13 T 28-03-2018 CO689_RS12330 b7e594102cdfbabcf9dc118b9f2381e8 207 PRINTS PR00096 Glutamine amidotransferase superfamily signature 69 80 4.3E-13 T 28-03-2018 CO689_RS12330 b7e594102cdfbabcf9dc118b9f2381e8 207 TIGRFAM TIGR00566 trpG_papA: glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase 1 181 3.9E-46 T 28-03-2018 IPR006221 Anthranilate synthase/para-aminobenzoate synthase like domain GO:0008152 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CO689_RS12330 b7e594102cdfbabcf9dc118b9f2381e8 207 SUPERFAMILY SSF52317 1 185 1.48E-42 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CO689_RS12330 b7e594102cdfbabcf9dc118b9f2381e8 207 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 40 54 4.0E-5 T 28-03-2018 CO689_RS12330 b7e594102cdfbabcf9dc118b9f2381e8 207 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 69 85 4.0E-5 T 28-03-2018 CO689_RS03195 77de6715450b95345a2253fa476d86ae 303 Pfam PF03547 Membrane transport protein 6 141 1.3E-10 T 28-03-2018 IPR004776 Membrane transport protein GO:0016021|GO:0055085 CO689_RS10560 272a353e3c58583140dee55959fd0d3e 1277 SUPERFAMILY SSF55846 304 459 8.63E-34 T 28-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 CO689_RS10560 272a353e3c58583140dee55959fd0d3e 1277 Gene3D G3DSA:1.10.530.10 1108 1265 4.8E-23 T 28-03-2018 CO689_RS10560 272a353e3c58583140dee55959fd0d3e 1277 Gene3D G3DSA:2.30.30.170 581 652 8.9E-10 T 28-03-2018 CO689_RS10560 272a353e3c58583140dee55959fd0d3e 1277 Gene3D G3DSA:2.30.30.170 507 576 2.0E-6 T 28-03-2018 CO689_RS10560 272a353e3c58583140dee55959fd0d3e 1277 Gene3D G3DSA:2.30.30.170 964 1031 6.7E-8 T 28-03-2018 CO689_RS10560 272a353e3c58583140dee55959fd0d3e 1277 Gene3D G3DSA:2.30.30.170 877 947 1.6E-10 T 28-03-2018 CO689_RS10560 272a353e3c58583140dee55959fd0d3e 1277 Gene3D G3DSA:2.30.30.170 794 869 1.3E-5 T 28-03-2018 CO689_RS10560 272a353e3c58583140dee55959fd0d3e 1277 SMART SM00047 1111 1271 1.9E-64 T 28-03-2018 IPR002901 Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain GO:0004040 CO689_RS10560 272a353e3c58583140dee55959fd0d3e 1277 Gene3D G3DSA:3.40.80.10 298 472 1.0E-26 T 28-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 CO689_RS10560 272a353e3c58583140dee55959fd0d3e 1277 Pfam PF01832 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase 1124 1260 3.4E-14 T 28-03-2018 IPR002901 Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain GO:0004040 CO689_RS10560 272a353e3c58583140dee55959fd0d3e 1277 SMART SM00644 305 444 1.9E-44 T 28-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 CO689_RS08045 5666b14f6c7e2bfe4d1904ebf8ec716f 1183 Pfam PF04560 RNA polymerase Rpb2, domain 7 1071 1146 8.9E-26 T 28-03-2018 IPR007641 RNA polymerase Rpb2, domain 7 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CO689_RS08045 5666b14f6c7e2bfe4d1904ebf8ec716f 1183 Gene3D G3DSA:3.90.1100.10 20 236 1.4E-57 T 28-03-2018 CO689_RS08045 5666b14f6c7e2bfe4d1904ebf8ec716f 1183 Gene3D G3DSA:3.90.1100.10 603 670 4.0E-13 T 28-03-2018 CO689_RS08045 5666b14f6c7e2bfe4d1904ebf8ec716f 1183 Gene3D G3DSA:3.90.1100.10 277 602 3.2E-83 T 28-03-2018 CO689_RS08045 5666b14f6c7e2bfe4d1904ebf8ec716f 1183 ProSitePatterns PS01166 RNA polymerases beta chain signature. 922 934 - T 28-03-2018 IPR007121 RNA polymerase, beta subunit, conserved site GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CO689_RS08045 5666b14f6c7e2bfe4d1904ebf8ec716f 1183 Gene3D G3DSA:2.40.270.10 846 1055 5.7E-78 T 28-03-2018 IPR007120 DNA-directed RNA polymerase, subunit 2, domain 6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CO689_RS08045 5666b14f6c7e2bfe4d1904ebf8ec716f 1183 Gene3D G3DSA:2.40.270.10 751 845 2.9E-11 T 28-03-2018 IPR007120 DNA-directed RNA polymerase, subunit 2, domain 6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CO689_RS08045 5666b14f6c7e2bfe4d1904ebf8ec716f 1183 TIGRFAM TIGR02013 rpoB: DNA-directed RNA polymerase, beta subunit 204 895 0.0 T 28-03-2018 IPR010243 DNA-directed RNA polymerase beta subunit, bacterial-type GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CO689_RS08045 5666b14f6c7e2bfe4d1904ebf8ec716f 1183 Pfam PF00562 RNA polymerase Rpb2, domain 6 676 1069 2.1E-165 T 28-03-2018 IPR007120 DNA-directed RNA polymerase, subunit 2, domain 6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CO689_RS08045 5666b14f6c7e2bfe4d1904ebf8ec716f 1183 Gene3D G3DSA:3.90.1800.10 1072 1115 1.0E-11 T 28-03-2018 CO689_RS08045 5666b14f6c7e2bfe4d1904ebf8ec716f 1183 Gene3D G3DSA:2.40.50.100 672 750 1.3E-22 T 28-03-2018 CO689_RS08045 5666b14f6c7e2bfe4d1904ebf8ec716f 1183 Pfam PF04563 RNA polymerase beta subunit 29 453 7.5E-29 T 28-03-2018 IPR007644 RNA polymerase, beta subunit, protrusion GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CO689_RS08045 5666b14f6c7e2bfe4d1904ebf8ec716f 1183 Pfam PF04561 RNA polymerase Rpb2, domain 2 140 289 1.1E-27 T 28-03-2018 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CO689_RS08045 5666b14f6c7e2bfe4d1904ebf8ec716f 1183 Pfam PF04561 RNA polymerase Rpb2, domain 2 373 409 7.4E-6 T 28-03-2018 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CO689_RS08045 5666b14f6c7e2bfe4d1904ebf8ec716f 1183 SUPERFAMILY SSF64484 14 289 0.0 T 28-03-2018 CO689_RS08045 5666b14f6c7e2bfe4d1904ebf8ec716f 1183 SUPERFAMILY SSF64484 377 1155 0.0 T 28-03-2018 CO689_RS08045 5666b14f6c7e2bfe4d1904ebf8ec716f 1183 Hamap MF_01321 DNA-directed RNA polymerase subunit beta [rpoB]. 15 1147 12.558 T 28-03-2018 IPR010243 DNA-directed RNA polymerase beta subunit, bacterial-type GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CO689_RS08045 5666b14f6c7e2bfe4d1904ebf8ec716f 1183 Pfam PF10385 RNA polymerase beta subunit external 1 domain 546 613 3.1E-25 T 28-03-2018 IPR019462 DNA-directed RNA polymerase, beta subunit, external 1 domain GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CO689_RS08045 5666b14f6c7e2bfe4d1904ebf8ec716f 1183 Pfam PF04565 RNA polymerase Rpb2, domain 3 468 536 5.3E-30 T 28-03-2018 IPR007645 RNA polymerase Rpb2, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CO689_RS03495 923fdb98927a81ba2e0af6d90d62f894 322 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 226 242 - T 28-03-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site CO689_RS03495 923fdb98927a81ba2e0af6d90d62f894 322 Gene3D G3DSA:3.40.50.720 110 288 2.6E-54 T 28-03-2018 CO689_RS03495 923fdb98927a81ba2e0af6d90d62f894 322 SUPERFAMILY SSF52283 1 138 1.89E-34 T 28-03-2018 CO689_RS03495 923fdb98927a81ba2e0af6d90d62f894 322 SUPERFAMILY SSF51735 100 286 9.1E-57 T 28-03-2018 IPR016040 NAD(P)-binding domain CO689_RS03495 923fdb98927a81ba2e0af6d90d62f894 322 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 109 286 1.4E-60 T 28-03-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 CO689_RS03495 923fdb98927a81ba2e0af6d90d62f894 322 Gene3D G3DSA:3.40.50.720 1 109 6.1E-32 T 28-03-2018 CO689_RS03495 923fdb98927a81ba2e0af6d90d62f894 322 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 5 319 5.0E-35 T 28-03-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 CO689_RS05680 40fb304178f30a518c692243014b9b55 1017 Gene3D G3DSA:1.10.10.10 344 417 8.3E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS05680 40fb304178f30a518c692243014b9b55 1017 SUPERFAMILY SSF88659 359 409 1.55E-8 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CO689_RS05680 40fb304178f30a518c692243014b9b55 1017 Pfam PF04545 Sigma-70, region 4 378 404 5.3E-9 T 28-03-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CO689_RS10795 b3d3ea79d32599cad561efc135abe513 404 Gene3D G3DSA:3.30.750.80 70 174 1.9E-27 T 28-03-2018 CO689_RS10795 b3d3ea79d32599cad561efc135abe513 404 SUPERFAMILY SSF53335 79 385 1.89E-61 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CO689_RS10795 b3d3ea79d32599cad561efc135abe513 404 Gene3D G3DSA:3.40.50.150 175 399 1.1E-26 T 28-03-2018 CO689_RS10795 b3d3ea79d32599cad561efc135abe513 404 Gene3D G3DSA:2.30.130.10 3 65 2.1E-17 T 28-03-2018 IPR002478 PUA domain GO:0003723 CO689_RS10795 b3d3ea79d32599cad561efc135abe513 404 Pfam PF10672 S-adenosylmethionine-dependent methyltransferase 149 369 2.8E-25 T 28-03-2018 IPR019614 S-adenosylmethionine-dependent methyltransferase GO:0008168 CO689_RS10795 b3d3ea79d32599cad561efc135abe513 404 SUPERFAMILY SSF88697 1 68 1.22E-17 T 28-03-2018 IPR015947 PUA-like domain CO689_RS13215 eb072cf64cafc6bbc7640eca3197f661 274 Pfam PF03618 Kinase/pyrophosphorylase 6 264 4.7E-95 T 28-03-2018 IPR005177 Bifunctional kinase-pyrophosphorylase GO:0005524|GO:0016772 CO689_RS13215 eb072cf64cafc6bbc7640eca3197f661 274 Gene3D G3DSA:3.40.50.300 12 273 1.8E-5 T 28-03-2018 CO689_RS13215 eb072cf64cafc6bbc7640eca3197f661 274 Hamap MF_00921 Putative pyruvate, phosphate dikinase regulatory protein. 4 269 58.549 T 28-03-2018 IPR026565 Putative pyruvate, phosphate dikinase regulatory protein CO689_RS12470 2b6f3961e945bd7ff978b2e461aa4813 387 Gene3D G3DSA:3.40.630.10 225 386 2.3E-16 T 28-03-2018 CO689_RS12470 2b6f3961e945bd7ff978b2e461aa4813 387 Gene3D G3DSA:3.40.630.10 3 218 2.1E-37 T 28-03-2018 CO689_RS12470 2b6f3961e945bd7ff978b2e461aa4813 387 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 10 367 7.7E-89 T 28-03-2018 IPR017439 Amidohydrolase GO:0016787 CO689_RS12470 2b6f3961e945bd7ff978b2e461aa4813 387 Pfam PF07687 Peptidase dimerisation domain 181 274 7.2E-7 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain CO689_RS12470 2b6f3961e945bd7ff978b2e461aa4813 387 Pfam PF01546 Peptidase family M20/M25/M40 65 378 1.2E-34 T 28-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CO689_RS12470 2b6f3961e945bd7ff978b2e461aa4813 387 PIRSF PIRSF005962 1 386 5.1E-114 T 28-03-2018 IPR017439 Amidohydrolase GO:0016787 CO689_RS12470 2b6f3961e945bd7ff978b2e461aa4813 387 SUPERFAMILY SSF55031 180 292 4.84E-18 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain CO689_RS12470 2b6f3961e945bd7ff978b2e461aa4813 387 SUPERFAMILY SSF53187 294 381 2.86E-70 T 28-03-2018 CO689_RS12470 2b6f3961e945bd7ff978b2e461aa4813 387 SUPERFAMILY SSF53187 6 193 2.86E-70 T 28-03-2018 CO689_RS04960 8c473512d218b2718847eb62736898de 531 SUPERFAMILY SSF53067 271 515 3.56E-9 T 28-03-2018 CO689_RS04960 8c473512d218b2718847eb62736898de 531 Gene3D G3DSA:3.30.420.40 8 261 5.8E-39 T 28-03-2018 CO689_RS04960 8c473512d218b2718847eb62736898de 531 Gene3D G3DSA:3.30.420.40 262 529 2.5E-28 T 28-03-2018 CO689_RS04960 8c473512d218b2718847eb62736898de 531 SUPERFAMILY SSF53067 15 263 2.78E-30 T 28-03-2018 CO689_RS04960 8c473512d218b2718847eb62736898de 531 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 275 472 1.3E-26 T 28-03-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 CO689_RS04960 8c473512d218b2718847eb62736898de 531 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 14 240 2.8E-15 T 28-03-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 CO689_RS05855 2938bf4f1df4dc37c1a5fce38ed85735 250 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 12 248 8.0E-57 T 28-03-2018 CO689_RS05855 2938bf4f1df4dc37c1a5fce38ed85735 250 Gene3D G3DSA:3.40.50.720 2 249 9.1E-59 T 28-03-2018 CO689_RS05855 2938bf4f1df4dc37c1a5fce38ed85735 250 SUPERFAMILY SSF51735 3 249 3.14E-70 T 28-03-2018 IPR016040 NAD(P)-binding domain CO689_RS05855 2938bf4f1df4dc37c1a5fce38ed85735 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 77 88 4.9E-29 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CO689_RS05855 2938bf4f1df4dc37c1a5fce38ed85735 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 156 175 4.9E-29 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CO689_RS05855 2938bf4f1df4dc37c1a5fce38ed85735 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 211 231 4.9E-29 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CO689_RS05855 2938bf4f1df4dc37c1a5fce38ed85735 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 177 194 4.9E-29 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CO689_RS05855 2938bf4f1df4dc37c1a5fce38ed85735 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 130 146 4.9E-29 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CO689_RS05855 2938bf4f1df4dc37c1a5fce38ed85735 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 4 21 4.9E-29 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CO689_RS05855 2938bf4f1df4dc37c1a5fce38ed85735 250 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 136 144 8.7E-8 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CO689_RS05855 2938bf4f1df4dc37c1a5fce38ed85735 250 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 156 175 8.7E-8 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CO689_RS05855 2938bf4f1df4dc37c1a5fce38ed85735 250 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 77 88 8.7E-8 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CO689_RS04420 05b9fb493c99be7a44a0ebc2164b5f23 228 Pfam PF04172 LrgB-like family 13 224 9.5E-66 T 28-03-2018 IPR007300 CidB/LrgB family CO689_RS02655 b3fdf3bf544aea507c2a929f23a74dec 478 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 313 324 - T 28-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CO689_RS02655 b3fdf3bf544aea507c2a929f23a74dec 478 SUPERFAMILY SSF100950 135 296 3.31E-40 T 28-03-2018 CO689_RS02655 b3fdf3bf544aea507c2a929f23a74dec 478 SUPERFAMILY SSF100950 64 89 3.31E-40 T 28-03-2018 CO689_RS02655 b3fdf3bf544aea507c2a929f23a74dec 478 Pfam PF13183 4Fe-4S dicluster domain 310 377 2.2E-9 T 28-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CO689_RS02655 b3fdf3bf544aea507c2a929f23a74dec 478 Pfam PF02589 LUD domain 71 295 2.7E-54 T 28-03-2018 IPR003741 LUD domain CO689_RS02655 b3fdf3bf544aea507c2a929f23a74dec 478 Gene3D G3DSA:3.30.70.20 299 321 0.0028 T 28-03-2018 CO689_RS02655 b3fdf3bf544aea507c2a929f23a74dec 478 TIGRFAM TIGR00273 TIGR00273: iron-sulfur cluster-binding protein 19 456 6.1E-197 T 28-03-2018 IPR004452 4Fe-4S binding protein GO:0019516 CO689_RS02655 b3fdf3bf544aea507c2a929f23a74dec 478 SUPERFAMILY SSF46548 286 390 1.99E-15 T 28-03-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 CO689_RS02655 b3fdf3bf544aea507c2a929f23a74dec 478 Gene3D G3DSA:3.40.50.10420 142 296 3.6E-44 T 28-03-2018 CO689_RS02655 b3fdf3bf544aea507c2a929f23a74dec 478 Gene3D G3DSA:3.40.50.10420 64 141 4.4E-10 T 28-03-2018 CO689_RS02655 b3fdf3bf544aea507c2a929f23a74dec 478 Gene3D G3DSA:3.30.70.20 322 474 4.3E-8 T 28-03-2018 CO689_RS02655 b3fdf3bf544aea507c2a929f23a74dec 478 Pfam PF11870 Domain of unknown function (DUF3390) 389 470 1.8E-13 T 28-03-2018 IPR024569 4Fe-4S binding protein, C-terminal CO689_RS09160 4fc485b09df913aebab22b280f9694fd 318 Gene3D G3DSA:3.50.50.60 250 313 6.4E-5 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CO689_RS09160 4fc485b09df913aebab22b280f9694fd 318 Gene3D G3DSA:3.50.50.60 130 239 3.2E-22 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CO689_RS09160 4fc485b09df913aebab22b280f9694fd 318 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 8 295 1.3E-49 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CO689_RS09160 4fc485b09df913aebab22b280f9694fd 318 SUPERFAMILY SSF51905 2 306 8.17E-57 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CO689_RS09160 4fc485b09df913aebab22b280f9694fd 318 ProSitePatterns PS00573 Pyridine nucleotide-disulphide oxidoreductases class-II active site. 136 156 - T 28-03-2018 IPR008255 Pyridine nucleotide-disulphide oxidoreductase, class-II, active site GO:0016491|GO:0055114 CO689_RS09160 4fc485b09df913aebab22b280f9694fd 318 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 42 57 1.0E-67 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CO689_RS09160 4fc485b09df913aebab22b280f9694fd 318 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 62 72 1.0E-67 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CO689_RS09160 4fc485b09df913aebab22b280f9694fd 318 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 269 287 1.0E-67 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CO689_RS09160 4fc485b09df913aebab22b280f9694fd 318 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 196 212 1.0E-67 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CO689_RS09160 4fc485b09df913aebab22b280f9694fd 318 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 129 141 1.0E-67 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CO689_RS09160 4fc485b09df913aebab22b280f9694fd 318 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 144 168 1.0E-67 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CO689_RS09160 4fc485b09df913aebab22b280f9694fd 318 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 235 256 1.0E-67 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CO689_RS09160 4fc485b09df913aebab22b280f9694fd 318 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 9 31 1.0E-67 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CO689_RS09160 4fc485b09df913aebab22b280f9694fd 318 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 107 115 1.0E-67 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CO689_RS09160 4fc485b09df913aebab22b280f9694fd 318 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 233 249 4.2E-38 T 28-03-2018 CO689_RS09160 4fc485b09df913aebab22b280f9694fd 318 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 10 29 4.2E-38 T 28-03-2018 CO689_RS09160 4fc485b09df913aebab22b280f9694fd 318 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 148 166 4.2E-38 T 28-03-2018 CO689_RS09160 4fc485b09df913aebab22b280f9694fd 318 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 259 281 4.2E-38 T 28-03-2018 CO689_RS09160 4fc485b09df913aebab22b280f9694fd 318 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 106 124 4.2E-38 T 28-03-2018 CO689_RS09160 4fc485b09df913aebab22b280f9694fd 318 TIGRFAM TIGR01292 TRX_reduct: thioredoxin-disulfide reductase 8 306 1.9E-117 T 28-03-2018 IPR005982 Thioredoxin reductase GO:0004791|GO:0005737|GO:0019430|GO:0055114 KEGG: 00450+1.8.1.9 CO689_RS09160 4fc485b09df913aebab22b280f9694fd 318 Gene3D G3DSA:3.50.50.60 1 129 3.5E-23 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CO689_RS11500 bf68ccf9e475fcde43629ddf022df16d 226 SUPERFAMILY SSF143548 19 137 9.02E-30 T 28-03-2018 IPR029009 Allosteric substrate binding domain Reactome: R-HSA-977347 CO689_RS11500 bf68ccf9e475fcde43629ddf022df16d 226 Gene3D G3DSA:3.30.70.260 144 218 1.2E-15 T 28-03-2018 CO689_RS11500 bf68ccf9e475fcde43629ddf022df16d 226 PIRSF PIRSF036692 1 220 1.7E-90 T 28-03-2018 IPR004643 Iron-sulphur-dependent L-serine dehydratase beta subunit GO:0003941|GO:0006094 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17 CO689_RS11500 bf68ccf9e475fcde43629ddf022df16d 226 Pfam PF03315 Serine dehydratase beta chain 14 130 1.9E-12 T 28-03-2018 IPR005131 Serine dehydratase beta chain GO:0003941|GO:0006094|GO:0051539 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17 CO689_RS11500 bf68ccf9e475fcde43629ddf022df16d 226 Gene3D G3DSA:3.30.1330.90 19 143 1.5E-24 T 28-03-2018 IPR029009 Allosteric substrate binding domain Reactome: R-HSA-977347 CO689_RS11500 bf68ccf9e475fcde43629ddf022df16d 226 Pfam PF01842 ACT domain 148 207 5.0E-9 T 28-03-2018 IPR002912 ACT domain CO689_RS11500 bf68ccf9e475fcde43629ddf022df16d 226 SUPERFAMILY SSF55021 136 215 7.5E-16 T 28-03-2018 CO689_RS11500 bf68ccf9e475fcde43629ddf022df16d 226 TIGRFAM TIGR00719 sda_beta: L-serine dehydratase, iron-sulfur-dependent, beta subunit 1 206 1.1E-76 T 28-03-2018 IPR004643 Iron-sulphur-dependent L-serine dehydratase beta subunit GO:0003941|GO:0006094 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17 CO689_RS05555 fa33ced6b15d0afeede765602d6de833 284 PRINTS PR00701 60kDa inner membrane protein signature 127 150 6.9E-6 T 28-03-2018 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 CO689_RS05555 fa33ced6b15d0afeede765602d6de833 284 PRINTS PR00701 60kDa inner membrane protein signature 213 236 6.9E-6 T 28-03-2018 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 CO689_RS05555 fa33ced6b15d0afeede765602d6de833 284 TIGRFAM TIGR03592 yidC_oxa1_cterm: membrane protein insertase, YidC/Oxa1 family 53 247 8.0E-47 T 28-03-2018 IPR028055 Membrane insertase YidC/Oxa1, C-terminal CO689_RS05555 fa33ced6b15d0afeede765602d6de833 284 Pfam PF02096 60Kd inner membrane protein 54 247 3.2E-42 T 28-03-2018 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 CO689_RS02045 f013b2192f83eda16025b10814b52c5f 100 Pfam PF07342 Protein of unknown function (DUF1474) 1 99 1.2E-16 T 28-03-2018 IPR009942 Protein of unknown function DUF1474 CO689_RS04105 34f13221a886e03298d3daa7dc4ec133 256 Gene3D G3DSA:2.40.50.40 150 217 2.7E-15 T 28-03-2018 CO689_RS04105 34f13221a886e03298d3daa7dc4ec133 256 Pfam PF04397 LytTr DNA-binding domain 158 253 6.3E-27 T 28-03-2018 IPR007492 LytTR DNA-binding domain GO:0003677 CO689_RS04105 34f13221a886e03298d3daa7dc4ec133 256 SMART SM00448 1 112 3.8E-24 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CO689_RS04105 34f13221a886e03298d3daa7dc4ec133 256 SMART SM00850 157 254 4.9E-33 T 28-03-2018 IPR007492 LytTR DNA-binding domain GO:0003677 CO689_RS04105 34f13221a886e03298d3daa7dc4ec133 256 Gene3D G3DSA:3.40.50.2300 1 149 1.8E-27 T 28-03-2018 CO689_RS04105 34f13221a886e03298d3daa7dc4ec133 256 Gene3D G3DSA:2.20.25.10 218 254 5.1E-15 T 28-03-2018 CO689_RS04105 34f13221a886e03298d3daa7dc4ec133 256 Pfam PF00072 Response regulator receiver domain 4 112 2.9E-22 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CO689_RS04105 34f13221a886e03298d3daa7dc4ec133 256 SUPERFAMILY SSF52172 2 165 2.56E-28 T 28-03-2018 IPR011006 CheY-like superfamily CO689_RS01345 b3bd422d34c28b9ac7ddfcebb63cafc4 141 PRINTS PR00332 Histidine triad family signature 26 44 2.2E-16 T 28-03-2018 IPR001310 Histidine triad (HIT) protein CO689_RS01345 b3bd422d34c28b9ac7ddfcebb63cafc4 141 PRINTS PR00332 Histidine triad family signature 93 103 2.2E-16 T 28-03-2018 IPR001310 Histidine triad (HIT) protein CO689_RS01345 b3bd422d34c28b9ac7ddfcebb63cafc4 141 PRINTS PR00332 Histidine triad family signature 5 21 2.2E-16 T 28-03-2018 IPR001310 Histidine triad (HIT) protein CO689_RS01345 b3bd422d34c28b9ac7ddfcebb63cafc4 141 ProSitePatterns PS00892 HIT domain signature. 86 104 - T 28-03-2018 IPR019808 Histidine triad, conserved site CO689_RS01345 b3bd422d34c28b9ac7ddfcebb63cafc4 141 Pfam PF01230 HIT domain 12 107 3.2E-26 T 28-03-2018 IPR001310 Histidine triad (HIT) protein CO689_RS01345 b3bd422d34c28b9ac7ddfcebb63cafc4 141 Gene3D G3DSA:3.30.428.10 1 141 9.1E-40 T 28-03-2018 IPR011146 HIT-like domain GO:0003824 CO689_RS01345 b3bd422d34c28b9ac7ddfcebb63cafc4 141 SUPERFAMILY SSF54197 3 140 1.36E-43 T 28-03-2018 IPR011146 HIT-like domain GO:0003824 CO689_RS00920 e99c22c8176764df844a207a7386a205 373 Pfam PF13242 HAD-hyrolase-like 281 367 6.0E-15 T 28-03-2018 CO689_RS00920 e99c22c8176764df844a207a7386a205 373 SUPERFAMILY SSF56784 143 372 3.05E-47 T 28-03-2018 IPR023214 HAD-like domain CO689_RS00920 e99c22c8176764df844a207a7386a205 373 SUPERFAMILY SSF56784 1 112 3.05E-47 T 28-03-2018 IPR023214 HAD-like domain CO689_RS00920 e99c22c8176764df844a207a7386a205 373 Gene3D G3DSA:3.40.50.1000 1 373 5.7E-23 T 28-03-2018 IPR023214 HAD-like domain CO689_RS08685 db622e6306a07154bf66a4455857d282 192 SUPERFAMILY SSF159234 2 160 5.36E-30 T 28-03-2018 IPR007295 Domain of unknown function DUF402 CO689_RS08685 db622e6306a07154bf66a4455857d282 192 Gene3D G3DSA:2.40.380.10 50 171 9.6E-23 T 28-03-2018 IPR007295 Domain of unknown function DUF402 CO689_RS08685 db622e6306a07154bf66a4455857d282 192 Pfam PF04167 Protein of unknown function (DUF402) 63 130 4.9E-18 T 28-03-2018 IPR007295 Domain of unknown function DUF402 CO689_RS13710 dbf684fafa2f9f258f9f8dace1411795 308 TIGRFAM TIGR00212 hemC: hydroxymethylbilane synthase 4 293 4.8E-110 T 28-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CO689_RS13710 dbf684fafa2f9f258f9f8dace1411795 308 Pfam PF01379 Porphobilinogen deaminase, dipyromethane cofactor binding domain 4 211 2.2E-76 T 28-03-2018 IPR022417 Porphobilinogen deaminase, N-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CO689_RS13710 dbf684fafa2f9f258f9f8dace1411795 308 Pfam PF03900 Porphobilinogen deaminase, C-terminal domain 225 292 4.5E-21 T 28-03-2018 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CO689_RS13710 dbf684fafa2f9f258f9f8dace1411795 308 SUPERFAMILY SSF54782 220 306 9.68E-22 T 28-03-2018 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CO689_RS13710 dbf684fafa2f9f258f9f8dace1411795 308 ProSitePatterns PS00533 Porphobilinogen deaminase cofactor-binding site. 230 246 - T 28-03-2018 IPR022419 Porphobilinogen deaminase, dipyrromethane cofactor binding site GO:0004418|GO:0018160|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CO689_RS13710 dbf684fafa2f9f258f9f8dace1411795 308 SUPERFAMILY SSF53850 2 217 2.67E-80 T 28-03-2018 CO689_RS13710 dbf684fafa2f9f258f9f8dace1411795 308 Hamap MF_00260 Porphobilinogen deaminase [hemC]. 3 295 39.053 T 28-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CO689_RS13710 dbf684fafa2f9f258f9f8dace1411795 308 Gene3D G3DSA:3.40.190.10 1 104 1.7E-40 T 28-03-2018 CO689_RS13710 dbf684fafa2f9f258f9f8dace1411795 308 Gene3D G3DSA:3.40.190.10 105 198 1.7E-34 T 28-03-2018 CO689_RS13710 dbf684fafa2f9f258f9f8dace1411795 308 Gene3D G3DSA:3.30.160.40 219 304 1.0E-19 T 28-03-2018 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CO689_RS13710 dbf684fafa2f9f258f9f8dace1411795 308 PRINTS PR00151 Porphobilinogen deaminase signature 43 63 2.6E-49 T 28-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CO689_RS13710 dbf684fafa2f9f258f9f8dace1411795 308 PRINTS PR00151 Porphobilinogen deaminase signature 141 158 2.6E-49 T 28-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CO689_RS13710 dbf684fafa2f9f258f9f8dace1411795 308 PRINTS PR00151 Porphobilinogen deaminase signature 122 139 2.6E-49 T 28-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CO689_RS13710 dbf684fafa2f9f258f9f8dace1411795 308 PRINTS PR00151 Porphobilinogen deaminase signature 74 93 2.6E-49 T 28-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CO689_RS13710 dbf684fafa2f9f258f9f8dace1411795 308 PRINTS PR00151 Porphobilinogen deaminase signature 229 246 2.6E-49 T 28-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CO689_RS13710 dbf684fafa2f9f258f9f8dace1411795 308 PIRSF PIRSF001438 1 308 6.0E-118 T 28-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CO689_RS10210 49dd1100df1174eb2534cc705ef4a398 331 TIGRFAM TIGR00233 trpS: tryptophan--tRNA ligase 3 325 1.7E-111 T 28-03-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 CO689_RS10210 49dd1100df1174eb2534cc705ef4a398 331 SUPERFAMILY SSF52374 3 325 3.29E-92 T 28-03-2018 CO689_RS10210 49dd1100df1174eb2534cc705ef4a398 331 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 64 83 1.3E-25 T 28-03-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 CO689_RS10210 49dd1100df1174eb2534cc705ef4a398 331 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 140 161 1.3E-25 T 28-03-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 CO689_RS10210 49dd1100df1174eb2534cc705ef4a398 331 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 14 30 1.3E-25 T 28-03-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 CO689_RS10210 49dd1100df1174eb2534cc705ef4a398 331 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 193 203 1.3E-25 T 28-03-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 CO689_RS10210 49dd1100df1174eb2534cc705ef4a398 331 Hamap MF_00140_B Tryptophan--tRNA ligase [trpS]. 1 326 41.035 T 28-03-2018 IPR024109 Tryptophan-tRNA ligase, bacterial-type GO:0004830 KEGG: 00970+6.1.1.2|Reactome: R-HSA-379726 CO689_RS10210 49dd1100df1174eb2534cc705ef4a398 331 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 10 19 - T 28-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 CO689_RS10210 49dd1100df1174eb2534cc705ef4a398 331 Pfam PF00579 tRNA synthetases class I (W and Y) 3 281 1.1E-82 T 28-03-2018 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 CO689_RS10210 49dd1100df1174eb2534cc705ef4a398 331 Gene3D G3DSA:3.40.50.620 2 188 1.6E-68 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CO689_RS10210 49dd1100df1174eb2534cc705ef4a398 331 Gene3D G3DSA:1.10.240.10 189 308 3.4E-34 T 28-03-2018 CO689_RS11725 62bc3b32519c1150f9b6d75e9aaf8d66 417 Pfam PF13184 NusA-like KH domain 229 296 9.1E-28 T 28-03-2018 IPR025249 KH domain, NusA-like GO:0003723 CO689_RS11725 62bc3b32519c1150f9b6d75e9aaf8d66 417 Gene3D G3DSA:3.30.300.20 198 275 8.1E-34 T 28-03-2018 IPR015946 K homology domain-like, alpha/beta CO689_RS11725 62bc3b32519c1150f9b6d75e9aaf8d66 417 SUPERFAMILY SSF54814 199 277 2.35E-29 T 28-03-2018 IPR009019 K homology domain, prokaryotic type GO:0003723 CO689_RS11725 62bc3b32519c1150f9b6d75e9aaf8d66 417 SMART SM00316 133 199 2.6E-5 T 28-03-2018 IPR022967 RNA-binding domain, S1 CO689_RS11725 62bc3b32519c1150f9b6d75e9aaf8d66 417 SUPERFAMILY SSF69705 2 125 1.57E-38 T 28-03-2018 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 CO689_RS11725 62bc3b32519c1150f9b6d75e9aaf8d66 417 SUPERFAMILY SSF50249 132 198 1.62E-15 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CO689_RS11725 62bc3b32519c1150f9b6d75e9aaf8d66 417 SUPERFAMILY SSF54814 278 341 5.1E-16 T 28-03-2018 IPR009019 K homology domain, prokaryotic type GO:0003723 CO689_RS11725 62bc3b32519c1150f9b6d75e9aaf8d66 417 Pfam PF00575 S1 RNA binding domain 132 195 1.7E-4 T 28-03-2018 IPR003029 S1 domain GO:0003676 CO689_RS11725 62bc3b32519c1150f9b6d75e9aaf8d66 417 Gene3D G3DSA:3.30.1480.10 1 129 3.9E-44 T 28-03-2018 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 CO689_RS11725 62bc3b32519c1150f9b6d75e9aaf8d66 417 Pfam PF08529 NusA N-terminal domain 4 124 8.9E-39 T 28-03-2018 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 CO689_RS11725 62bc3b32519c1150f9b6d75e9aaf8d66 417 Gene3D G3DSA:2.40.50.140 136 197 9.2E-11 T 28-03-2018 CO689_RS11725 62bc3b32519c1150f9b6d75e9aaf8d66 417 SMART SM00322 229 301 0.12 T 28-03-2018 IPR004087 K Homology domain GO:0003676 CO689_RS11725 62bc3b32519c1150f9b6d75e9aaf8d66 417 SMART SM00322 302 396 0.16 T 28-03-2018 IPR004087 K Homology domain GO:0003676 CO689_RS11725 62bc3b32519c1150f9b6d75e9aaf8d66 417 Gene3D G3DSA:3.30.300.20 277 347 1.2E-16 T 28-03-2018 IPR015946 K homology domain-like, alpha/beta CO689_RS11725 62bc3b32519c1150f9b6d75e9aaf8d66 417 TIGRFAM TIGR01953 NusA: transcription termination factor NusA 5 341 1.3E-124 T 28-03-2018 IPR010213 Transcription termination factor NusA GO:0003723 CO689_RS11725 62bc3b32519c1150f9b6d75e9aaf8d66 417 Hamap MF_00945_B Transcription termination/antitermination protein NusA [nusA]. 2 402 29.328 T 28-03-2018 IPR030842 Transcription termination/antitermination protein NusA, bacterial GO:0006353|GO:0031564 CO689_RS02835 f472d5a90e70c1043e5ef2f4e2c19501 456 Pfam PF07670 Nucleoside recognition 142 239 1.5E-8 T 28-03-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 CO689_RS11045 b831ed6de250b3f95ac048ea3ebe2e22 248 Gene3D G3DSA:3.40.1280.10 104 248 2.2E-35 T 28-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal CO689_RS11045 b831ed6de250b3f95ac048ea3ebe2e22 248 SUPERFAMILY SSF75217 104 246 1.64E-34 T 28-03-2018 IPR029028 Alpha/beta knot methyltransferases CO689_RS11045 b831ed6de250b3f95ac048ea3ebe2e22 248 SMART SM00967 31 100 3.7E-12 T 28-03-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 CO689_RS11045 b831ed6de250b3f95ac048ea3ebe2e22 248 Pfam PF08032 RNA 2'-O ribose methyltransferase substrate binding 31 98 2.0E-9 T 28-03-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 CO689_RS11045 b831ed6de250b3f95ac048ea3ebe2e22 248 Pfam PF00588 SpoU rRNA Methylase family 109 244 2.5E-32 T 28-03-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 CO689_RS11045 b831ed6de250b3f95ac048ea3ebe2e22 248 SUPERFAMILY SSF55315 3 98 1.29E-23 T 28-03-2018 IPR029064 50S ribosomal protein L30e-like CO689_RS11045 b831ed6de250b3f95ac048ea3ebe2e22 248 Gene3D G3DSA:3.30.1330.30 3 99 6.5E-22 T 28-03-2018 IPR029064 50S ribosomal protein L30e-like CO689_RS07720 9de2e332b9629a5d5e023415902734d2 321 SMART SM01400 11 127 2.8E-80 T 28-03-2018 CO689_RS07720 9de2e332b9629a5d5e023415902734d2 321 Gene3D G3DSA:3.40.50.2020 8 162 5.8E-68 T 28-03-2018 CO689_RS07720 9de2e332b9629a5d5e023415902734d2 321 SUPERFAMILY SSF53271 76 312 9.25E-66 T 28-03-2018 IPR029057 Phosphoribosyltransferase-like CO689_RS07720 9de2e332b9629a5d5e023415902734d2 321 Hamap MF_00583_B Ribose-phosphate pyrophosphokinase [prs]. 11 321 50.139 T 28-03-2018 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 CO689_RS07720 9de2e332b9629a5d5e023415902734d2 321 ProSitePatterns PS00114 Phosphoribosyl pyrophosphate synthase signature. 135 150 - T 28-03-2018 IPR000842 Phosphoribosyl pyrophosphate synthetase, conserved site GO:0000287|GO:0004749|GO:0009156|GO:0044249 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1|Reactome: R-HSA-73843 CO689_RS07720 9de2e332b9629a5d5e023415902734d2 321 TIGRFAM TIGR01251 ribP_PPkin: ribose-phosphate diphosphokinase 12 321 1.0E-125 T 28-03-2018 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 CO689_RS07720 9de2e332b9629a5d5e023415902734d2 321 Pfam PF13793 N-terminal domain of ribose phosphate pyrophosphokinase 11 127 6.7E-50 T 28-03-2018 IPR029099 Ribose-phosphate pyrophosphokinase, N-terminal domain KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 CO689_RS07720 9de2e332b9629a5d5e023415902734d2 321 Pfam PF14572 Phosphoribosyl synthetase-associated domain 212 320 4.3E-26 T 28-03-2018 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 CO689_RS07720 9de2e332b9629a5d5e023415902734d2 321 Gene3D G3DSA:3.40.50.2020 163 299 3.4E-40 T 28-03-2018 CO689_RS06100 099db5c27b406bddfe340bfa0c6b8af6 597 PRINTS PR00742 Glycosyl hydrolase family 35 signature 13 30 1.6E-49 T 28-03-2018 IPR001944 Glycoside hydrolase, family 35 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 CO689_RS06100 099db5c27b406bddfe340bfa0c6b8af6 597 PRINTS PR00742 Glycosyl hydrolase family 35 signature 34 52 1.6E-49 T 28-03-2018 IPR001944 Glycoside hydrolase, family 35 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 CO689_RS06100 099db5c27b406bddfe340bfa0c6b8af6 597 PRINTS PR00742 Glycosyl hydrolase family 35 signature 271 286 1.6E-49 T 28-03-2018 IPR001944 Glycoside hydrolase, family 35 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 CO689_RS06100 099db5c27b406bddfe340bfa0c6b8af6 597 PRINTS PR00742 Glycosyl hydrolase family 35 signature 89 108 1.6E-49 T 28-03-2018 IPR001944 Glycoside hydrolase, family 35 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 CO689_RS06100 099db5c27b406bddfe340bfa0c6b8af6 597 PRINTS PR00742 Glycosyl hydrolase family 35 signature 298 314 1.6E-49 T 28-03-2018 IPR001944 Glycoside hydrolase, family 35 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 CO689_RS06100 099db5c27b406bddfe340bfa0c6b8af6 597 PRINTS PR00742 Glycosyl hydrolase family 35 signature 530 546 1.6E-49 T 28-03-2018 IPR001944 Glycoside hydrolase, family 35 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 CO689_RS06100 099db5c27b406bddfe340bfa0c6b8af6 597 PRINTS PR00742 Glycosyl hydrolase family 35 signature 144 159 1.6E-49 T 28-03-2018 IPR001944 Glycoside hydrolase, family 35 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 CO689_RS06100 099db5c27b406bddfe340bfa0c6b8af6 597 PRINTS PR00742 Glycosyl hydrolase family 35 signature 236 251 1.6E-49 T 28-03-2018 IPR001944 Glycoside hydrolase, family 35 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 CO689_RS06100 099db5c27b406bddfe340bfa0c6b8af6 597 Gene3D G3DSA:2.60.120.260 356 475 5.0E-26 T 28-03-2018 IPR008979 Galactose-binding domain-like CO689_RS06100 099db5c27b406bddfe340bfa0c6b8af6 597 PIRSF PIRSF006336 2 588 2.5E-171 T 28-03-2018 IPR026283 Beta-galactosidase 1-like GO:0004565 CO689_RS06100 099db5c27b406bddfe340bfa0c6b8af6 597 SUPERFAMILY SSF51445 9 332 2.43E-101 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CO689_RS06100 099db5c27b406bddfe340bfa0c6b8af6 597 SUPERFAMILY SSF49785 446 580 5.95E-27 T 28-03-2018 IPR008979 Galactose-binding domain-like CO689_RS06100 099db5c27b406bddfe340bfa0c6b8af6 597 Gene3D G3DSA:2.60.120.260 476 595 4.3E-23 T 28-03-2018 IPR008979 Galactose-binding domain-like CO689_RS06100 099db5c27b406bddfe340bfa0c6b8af6 597 Gene3D G3DSA:3.20.20.80 5 334 6.9E-79 T 28-03-2018 CO689_RS06100 099db5c27b406bddfe340bfa0c6b8af6 597 Pfam PF01301 Glycosyl hydrolases family 35 9 329 4.2E-118 T 28-03-2018 IPR031330 Glycoside hydrolase 35, catalytic domain KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 CO689_RS10705 8cfd802e8f65e802ec8c1375f299b6c0 358 Gene3D G3DSA:3.40.630.10 168 357 1.7E-44 T 28-03-2018 CO689_RS10705 8cfd802e8f65e802ec8c1375f299b6c0 358 SUPERFAMILY SSF101821 70 180 3.05E-35 T 28-03-2018 CO689_RS10705 8cfd802e8f65e802ec8c1375f299b6c0 358 Gene3D G3DSA:2.40.30.40 69 161 1.1E-35 T 28-03-2018 IPR023367 Peptidase M42, domain 2 CO689_RS10705 8cfd802e8f65e802ec8c1375f299b6c0 358 SUPERFAMILY SSF53187 4 80 6.29E-68 T 28-03-2018 CO689_RS10705 8cfd802e8f65e802ec8c1375f299b6c0 358 SUPERFAMILY SSF53187 172 356 6.29E-68 T 28-03-2018 CO689_RS10705 8cfd802e8f65e802ec8c1375f299b6c0 358 PIRSF PIRSF001123 1 358 4.0E-142 T 28-03-2018 IPR008007 Peptidase M42 CO689_RS10705 8cfd802e8f65e802ec8c1375f299b6c0 358 Pfam PF05343 M42 glutamyl aminopeptidase 45 340 1.1E-109 T 28-03-2018 IPR008007 Peptidase M42 CO689_RS06545 e9fd68f8ad8b9866900898aed20166be 264 SUPERFAMILY SSF56601 9 146 1.77E-13 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CO689_RS06545 e9fd68f8ad8b9866900898aed20166be 264 SUPERFAMILY SSF56601 168 260 1.02E-16 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CO689_RS06545 e9fd68f8ad8b9866900898aed20166be 264 Pfam PF13354 Beta-lactamase enzyme family 180 260 1.6E-5 T 28-03-2018 CO689_RS06545 e9fd68f8ad8b9866900898aed20166be 264 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 8 106 1.8E-12 T 28-03-2018 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 CO689_RS06545 e9fd68f8ad8b9866900898aed20166be 264 Gene3D G3DSA:3.40.710.10 5 164 7.2E-8 T 28-03-2018 CO689_RS06545 e9fd68f8ad8b9866900898aed20166be 264 Gene3D G3DSA:3.40.710.10 175 264 1.7E-11 T 28-03-2018 CO689_RS13295 5f13546f5450d7abb1072c2c0dacb668 377 Hamap MF_01152 Chaperone protein DnaJ [dnaJ]. 2 373 40.701 T 28-03-2018 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 CO689_RS13295 5f13546f5450d7abb1072c2c0dacb668 377 Gene3D G3DSA:2.10.230.10 144 201 9.4E-17 T 28-03-2018 CO689_RS13295 5f13546f5450d7abb1072c2c0dacb668 377 SMART SM00271 4 61 5.0E-33 T 28-03-2018 IPR001623 DnaJ domain CO689_RS13295 5f13546f5450d7abb1072c2c0dacb668 377 Pfam PF00684 DnaJ central domain 147 211 6.5E-14 T 28-03-2018 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 CO689_RS13295 5f13546f5450d7abb1072c2c0dacb668 377 Pfam PF01556 DnaJ C terminal domain 120 337 4.3E-42 T 28-03-2018 IPR002939 Chaperone DnaJ, C-terminal CO689_RS13295 5f13546f5450d7abb1072c2c0dacb668 377 SUPERFAMILY SSF49493 114 155 1.02E-20 T 28-03-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 CO689_RS13295 5f13546f5450d7abb1072c2c0dacb668 377 SUPERFAMILY SSF49493 218 260 1.02E-20 T 28-03-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 CO689_RS13295 5f13546f5450d7abb1072c2c0dacb668 377 Gene3D G3DSA:2.60.260.20 259 370 8.0E-27 T 28-03-2018 CO689_RS13295 5f13546f5450d7abb1072c2c0dacb668 377 Pfam PF00226 DnaJ domain 5 66 3.0E-28 T 28-03-2018 IPR001623 DnaJ domain CO689_RS13295 5f13546f5450d7abb1072c2c0dacb668 377 SUPERFAMILY SSF46565 2 103 3.01E-38 T 28-03-2018 IPR001623 DnaJ domain CO689_RS13295 5f13546f5450d7abb1072c2c0dacb668 377 SUPERFAMILY SSF49493 263 348 1.96E-23 T 28-03-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 CO689_RS13295 5f13546f5450d7abb1072c2c0dacb668 377 Gene3D G3DSA:2.60.260.20 202 258 1.3E-18 T 28-03-2018 CO689_RS13295 5f13546f5450d7abb1072c2c0dacb668 377 SUPERFAMILY SSF57938 134 214 3.01E-19 T 28-03-2018 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 CO689_RS13295 5f13546f5450d7abb1072c2c0dacb668 377 TIGRFAM TIGR02349 DnaJ_bact: chaperone protein DnaJ 5 353 7.0E-141 T 28-03-2018 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 CO689_RS13295 5f13546f5450d7abb1072c2c0dacb668 377 ProSitePatterns PS00636 Nt-dnaJ domain signature. 46 65 - T 28-03-2018 IPR018253 DnaJ domain, conserved site CO689_RS13295 5f13546f5450d7abb1072c2c0dacb668 377 PRINTS PR00625 DnaJ domain signature 61 80 2.6E-32 T 28-03-2018 IPR001623 DnaJ domain CO689_RS13295 5f13546f5450d7abb1072c2c0dacb668 377 PRINTS PR00625 DnaJ domain signature 7 25 2.6E-32 T 28-03-2018 IPR001623 DnaJ domain CO689_RS13295 5f13546f5450d7abb1072c2c0dacb668 377 PRINTS PR00625 DnaJ domain signature 25 40 2.6E-32 T 28-03-2018 IPR001623 DnaJ domain CO689_RS13295 5f13546f5450d7abb1072c2c0dacb668 377 PRINTS PR00625 DnaJ domain signature 41 61 2.6E-32 T 28-03-2018 IPR001623 DnaJ domain CO689_RS13295 5f13546f5450d7abb1072c2c0dacb668 377 Gene3D G3DSA:1.10.287.110 1 115 7.5E-39 T 28-03-2018 IPR001623 DnaJ domain CO689_RS09200 4e177a6c2ecf07691949da99b5247e0f 233 SUPERFAMILY SSF47413 1 53 3.38E-7 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CO689_RS09200 4e177a6c2ecf07691949da99b5247e0f 233 Gene3D G3DSA:1.10.3100.10 1 86 2.1E-8 T 28-03-2018 IPR027910 YdiL-like domain CO689_RS07500 75c067d4b205cbb63708d9b193f1794e 239 SUPERFAMILY SSF64288 76 236 2.04E-29 T 28-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain CO689_RS07500 75c067d4b205cbb63708d9b193f1794e 239 SMART SM00345 10 69 3.0E-14 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CO689_RS07500 75c067d4b205cbb63708d9b193f1794e 239 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 43 59 4.0E-8 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CO689_RS07500 75c067d4b205cbb63708d9b193f1794e 239 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 29 43 4.0E-8 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CO689_RS07500 75c067d4b205cbb63708d9b193f1794e 239 Pfam PF00392 Bacterial regulatory proteins, gntR family 9 69 1.5E-16 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CO689_RS07500 75c067d4b205cbb63708d9b193f1794e 239 SUPERFAMILY SSF46785 5 73 6.59E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS07500 75c067d4b205cbb63708d9b193f1794e 239 Gene3D G3DSA:3.40.1410.10 75 239 1.6E-19 T 28-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain CO689_RS07500 75c067d4b205cbb63708d9b193f1794e 239 Pfam PF07702 UTRA domain 97 231 8.3E-20 T 28-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 CO689_RS07500 75c067d4b205cbb63708d9b193f1794e 239 TIGRFAM TIGR02404 trehalos_R_Bsub: trehalose operon repressor 6 239 5.4E-71 T 28-03-2018 IPR012770 Trehalose operon transcriptional repressor CO689_RS07500 75c067d4b205cbb63708d9b193f1794e 239 Gene3D G3DSA:1.10.10.10 1 70 1.3E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS07500 75c067d4b205cbb63708d9b193f1794e 239 SMART SM00866 91 232 4.9E-13 T 28-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 CO689_RS13765 03a265bb161e97cc0b96f0a631809b99 495 Pfam PF00324 Amino acid permease 19 477 9.1E-134 T 28-03-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0006810|GO:0016020|GO:0055085 CO689_RS13765 03a265bb161e97cc0b96f0a631809b99 495 PIRSF PIRSF006060 1 492 1.5E-85 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CO689_RS13765 03a265bb161e97cc0b96f0a631809b99 495 ProSitePatterns PS00218 Amino acid permeases signature. 44 75 - T 28-03-2018 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 CO689_RS10605 8c3d29f89c7055ec845d375f183f365e 204 Pfam PF03413 Peptidase propeptide and YPEB domain 68 121 1.3E-7 T 28-03-2018 IPR025711 PepSY domain CO689_RS10605 8c3d29f89c7055ec845d375f183f365e 204 Pfam PF03413 Peptidase propeptide and YPEB domain 144 201 2.9E-7 T 28-03-2018 IPR025711 PepSY domain CO689_RS10605 8c3d29f89c7055ec845d375f183f365e 204 Gene3D G3DSA:3.10.450.40 66 125 3.0E-10 T 28-03-2018 CO689_RS10605 8c3d29f89c7055ec845d375f183f365e 204 Gene3D G3DSA:3.10.450.40 144 202 4.7E-9 T 28-03-2018 CO689_RS11875 85dee6eff388bbf02198f301c68064b9 276 Gene3D G3DSA:1.10.10.10 1 77 9.2E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS11875 85dee6eff388bbf02198f301c68064b9 276 SUPERFAMILY SSF53850 87 276 9.77E-27 T 28-03-2018 CO689_RS11875 85dee6eff388bbf02198f301c68064b9 276 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 16 27 9.3E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CO689_RS11875 85dee6eff388bbf02198f301c68064b9 276 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 27 37 9.3E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CO689_RS11875 85dee6eff388bbf02198f301c68064b9 276 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 37 48 9.3E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CO689_RS11875 85dee6eff388bbf02198f301c68064b9 276 Pfam PF03466 LysR substrate binding domain 87 275 6.9E-27 T 28-03-2018 IPR005119 LysR, substrate-binding CO689_RS11875 85dee6eff388bbf02198f301c68064b9 276 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 60 1.0E-14 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CO689_RS11875 85dee6eff388bbf02198f301c68064b9 276 Gene3D G3DSA:3.40.190.10 171 250 1.2E-7 T 28-03-2018 CO689_RS11875 85dee6eff388bbf02198f301c68064b9 276 SUPERFAMILY SSF46785 4 109 2.2E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS11875 85dee6eff388bbf02198f301c68064b9 276 Gene3D G3DSA:3.40.190.10 78 170 9.5E-14 T 28-03-2018 CO689_RS10175 4e939f33cea1bb3a1ed267fe2949ef64 360 Pfam PF00005 ABC transporter 26 184 1.5E-30 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CO689_RS10175 4e939f33cea1bb3a1ed267fe2949ef64 360 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 234 320 3.3E-17 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CO689_RS10175 4e939f33cea1bb3a1ed267fe2949ef64 360 ProSitePatterns PS00211 ABC transporters family signature. 157 171 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CO689_RS10175 4e939f33cea1bb3a1ed267fe2949ef64 360 Gene3D G3DSA:3.40.50.300 2 336 2.4E-77 T 28-03-2018 CO689_RS10175 4e939f33cea1bb3a1ed267fe2949ef64 360 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 236 299 6.6E-14 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CO689_RS10175 4e939f33cea1bb3a1ed267fe2949ef64 360 SUPERFAMILY SSF52540 5 255 7.55E-73 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CO689_RS10175 4e939f33cea1bb3a1ed267fe2949ef64 360 SMART SM00382 34 234 8.7E-15 T 28-03-2018 IPR003593 AAA+ ATPase domain CO689_RS02675 be9511bfc048fdc8d8a12fd318701e56 101 SUPERFAMILY SSF46785 8 96 3.44E-25 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS02675 be9511bfc048fdc8d8a12fd318701e56 101 SMART SM00418 16 94 3.7E-29 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CO689_RS02675 be9511bfc048fdc8d8a12fd318701e56 101 Gene3D G3DSA:1.10.10.10 1 100 1.8E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS02675 be9511bfc048fdc8d8a12fd318701e56 101 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 65 80 4.8E-13 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CO689_RS02675 be9511bfc048fdc8d8a12fd318701e56 101 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 50 65 4.8E-13 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CO689_RS02675 be9511bfc048fdc8d8a12fd318701e56 101 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 18 33 4.8E-13 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CO689_RS02675 be9511bfc048fdc8d8a12fd318701e56 101 Pfam PF01022 Bacterial regulatory protein, arsR family 24 68 3.1E-15 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CO689_RS07245 16377b7db46e88d36d1ec17e8a7ae822 488 Gene3D G3DSA:3.20.20.70 3 483 4.8E-110 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CO689_RS07245 16377b7db46e88d36d1ec17e8a7ae822 488 SMART SM00116 161 208 9.0E-5 T 28-03-2018 IPR000644 CBS domain CO689_RS07245 16377b7db46e88d36d1ec17e8a7ae822 488 SMART SM00116 98 148 3.1E-9 T 28-03-2018 IPR000644 CBS domain CO689_RS07245 16377b7db46e88d36d1ec17e8a7ae822 488 SUPERFAMILY SSF54631 85 206 1.64E-28 T 28-03-2018 CO689_RS07245 16377b7db46e88d36d1ec17e8a7ae822 488 Pfam PF00571 CBS domain 97 144 1.5E-7 T 28-03-2018 IPR000644 CBS domain CO689_RS07245 16377b7db46e88d36d1ec17e8a7ae822 488 Pfam PF00571 CBS domain 153 203 5.1E-8 T 28-03-2018 IPR000644 CBS domain CO689_RS07245 16377b7db46e88d36d1ec17e8a7ae822 488 SMART SM01240 9 475 0.0 T 28-03-2018 CO689_RS07245 16377b7db46e88d36d1ec17e8a7ae822 488 Pfam PF00478 IMP dehydrogenase / GMP reductase domain 10 475 3.8E-164 T 28-03-2018 IPR001093 IMP dehydrogenase/GMP reductase GO:0003824|GO:0055114 CO689_RS07245 16377b7db46e88d36d1ec17e8a7ae822 488 SUPERFAMILY SSF51412 219 479 2.75E-121 T 28-03-2018 CO689_RS07245 16377b7db46e88d36d1ec17e8a7ae822 488 SUPERFAMILY SSF51412 5 92 2.75E-121 T 28-03-2018 CO689_RS07245 16377b7db46e88d36d1ec17e8a7ae822 488 TIGRFAM TIGR01302 IMP_dehydrog: inosine-5'-monophosphate dehydrogenase 10 457 9.7E-199 T 28-03-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 CO689_RS07245 16377b7db46e88d36d1ec17e8a7ae822 488 Hamap MF_01964 Inosine-5'-monophosphate dehydrogenase [guaB]. 10 488 82.568 T 28-03-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 CO689_RS07245 16377b7db46e88d36d1ec17e8a7ae822 488 PIRSF PIRSF000130 1 488 1.1E-207 T 28-03-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 CO689_RS07245 16377b7db46e88d36d1ec17e8a7ae822 488 ProSitePatterns PS00487 IMP dehydrogenase / GMP reductase signature. 297 309 - T 28-03-2018 IPR015875 IMP dehydrogenase / GMP reductase, conserved site GO:0016491|GO:0055114 CO689_RS07005 4852d577bd2cb1d085e01cd95c3c85c9 639 Gene3D G3DSA:3.30.565.10 20 230 1.8E-75 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CO689_RS07005 4852d577bd2cb1d085e01cd95c3c85c9 639 PRINTS PR01159 DNA gyrase subunit B signature 10 20 2.1E-72 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CO689_RS07005 4852d577bd2cb1d085e01cd95c3c85c9 639 PRINTS PR01159 DNA gyrase subunit B signature 380 400 2.1E-72 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CO689_RS07005 4852d577bd2cb1d085e01cd95c3c85c9 639 PRINTS PR01159 DNA gyrase subunit B signature 366 380 2.1E-72 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CO689_RS07005 4852d577bd2cb1d085e01cd95c3c85c9 639 PRINTS PR01159 DNA gyrase subunit B signature 200 213 2.1E-72 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CO689_RS07005 4852d577bd2cb1d085e01cd95c3c85c9 639 PRINTS PR01159 DNA gyrase subunit B signature 609 625 2.1E-72 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CO689_RS07005 4852d577bd2cb1d085e01cd95c3c85c9 639 PRINTS PR01159 DNA gyrase subunit B signature 226 248 2.1E-72 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CO689_RS07005 4852d577bd2cb1d085e01cd95c3c85c9 639 PRINTS PR01159 DNA gyrase subunit B signature 318 334 2.1E-72 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CO689_RS07005 4852d577bd2cb1d085e01cd95c3c85c9 639 PRINTS PR01159 DNA gyrase subunit B signature 593 605 2.1E-72 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CO689_RS07005 4852d577bd2cb1d085e01cd95c3c85c9 639 PRINTS PR01159 DNA gyrase subunit B signature 185 200 2.1E-72 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CO689_RS07005 4852d577bd2cb1d085e01cd95c3c85c9 639 PRINTS PR01159 DNA gyrase subunit B signature 476 485 2.1E-72 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CO689_RS07005 4852d577bd2cb1d085e01cd95c3c85c9 639 SMART SM00433 39 633 0.0 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CO689_RS07005 4852d577bd2cb1d085e01cd95c3c85c9 639 SMART SM00387 35 179 9.9E-24 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CO689_RS07005 4852d577bd2cb1d085e01cd95c3c85c9 639 Pfam PF00204 DNA gyrase B 227 396 9.7E-61 T 28-03-2018 IPR013506 DNA topoisomerase, type IIA, subunit B, domain 2 GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CO689_RS07005 4852d577bd2cb1d085e01cd95c3c85c9 639 Hamap MF_01898 DNA gyrase subunit B [gyrB]. 7 639 92.474 T 28-03-2018 IPR011557 DNA gyrase, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 CO689_RS07005 4852d577bd2cb1d085e01cd95c3c85c9 639 Gene3D G3DSA:3.40.50.670 405 636 2.7E-101 T 28-03-2018 IPR013759 DNA topoisomerase, type IIA, central domain GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CO689_RS07005 4852d577bd2cb1d085e01cd95c3c85c9 639 Pfam PF01751 Toprim domain 425 536 3.6E-17 T 28-03-2018 IPR006171 TOPRIM domain CO689_RS07005 4852d577bd2cb1d085e01cd95c3c85c9 639 SUPERFAMILY SSF55874 10 218 2.1E-72 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CO689_RS07005 4852d577bd2cb1d085e01cd95c3c85c9 639 ProSitePatterns PS00177 DNA topoisomerase II signature. 428 436 - T 28-03-2018 IPR018522 DNA topoisomerase, type IIA, conserved site GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CO689_RS07005 4852d577bd2cb1d085e01cd95c3c85c9 639 Gene3D G3DSA:3.30.230.10 231 398 1.2E-61 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CO689_RS07005 4852d577bd2cb1d085e01cd95c3c85c9 639 PRINTS PR00418 DNA topoisomerase II family signature 426 440 4.2E-69 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CO689_RS07005 4852d577bd2cb1d085e01cd95c3c85c9 639 PRINTS PR00418 DNA topoisomerase II family signature 510 527 4.2E-69 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CO689_RS07005 4852d577bd2cb1d085e01cd95c3c85c9 639 PRINTS PR00418 DNA topoisomerase II family signature 572 588 4.2E-69 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CO689_RS07005 4852d577bd2cb1d085e01cd95c3c85c9 639 PRINTS PR00418 DNA topoisomerase II family signature 117 131 4.2E-69 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CO689_RS07005 4852d577bd2cb1d085e01cd95c3c85c9 639 PRINTS PR00418 DNA topoisomerase II family signature 74 87 4.2E-69 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CO689_RS07005 4852d577bd2cb1d085e01cd95c3c85c9 639 PRINTS PR00418 DNA topoisomerase II family signature 492 508 4.2E-69 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CO689_RS07005 4852d577bd2cb1d085e01cd95c3c85c9 639 PRINTS PR00418 DNA topoisomerase II family signature 530 542 4.2E-69 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CO689_RS07005 4852d577bd2cb1d085e01cd95c3c85c9 639 PRINTS PR00418 DNA topoisomerase II family signature 39 54 4.2E-69 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CO689_RS07005 4852d577bd2cb1d085e01cd95c3c85c9 639 PRINTS PR00418 DNA topoisomerase II family signature 274 287 4.2E-69 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CO689_RS07005 4852d577bd2cb1d085e01cd95c3c85c9 639 TIGRFAM TIGR01059 gyrB: DNA gyrase, B subunit 10 635 1.5E-301 T 28-03-2018 IPR011557 DNA gyrase, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 CO689_RS07005 4852d577bd2cb1d085e01cd95c3c85c9 639 SUPERFAMILY SSF54211 227 397 3.03E-57 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CO689_RS07005 4852d577bd2cb1d085e01cd95c3c85c9 639 Pfam PF00986 DNA gyrase B subunit, carboxyl terminus 569 629 2.0E-28 T 28-03-2018 IPR002288 DNA gyrase B subunit, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 CO689_RS07005 4852d577bd2cb1d085e01cd95c3c85c9 639 SUPERFAMILY SSF56719 400 631 5.49E-91 T 28-03-2018 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Reactome: R-HSA-4615885 CO689_RS07005 4852d577bd2cb1d085e01cd95c3c85c9 639 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 36 178 1.6E-21 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CO689_RS02130 2d4a9ea71dcc35a5b0aadca7a7bd166c 494 SUPERFAMILY SSF75005 29 331 1.34E-49 T 28-03-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain CO689_RS02130 2d4a9ea71dcc35a5b0aadca7a7bd166c 494 SUPERFAMILY SSF49899 334 485 1.35E-23 T 28-03-2018 IPR013320 Concanavalin A-like lectin/glucanase domain CO689_RS02130 2d4a9ea71dcc35a5b0aadca7a7bd166c 494 SMART SM00640 38 447 2.5E-21 T 28-03-2018 IPR001362 Glycoside hydrolase, family 32 GO:0004553|GO:0005975 CO689_RS02130 2d4a9ea71dcc35a5b0aadca7a7bd166c 494 Pfam PF00251 Glycosyl hydrolases family 32 N-terminal domain 38 331 3.1E-37 T 28-03-2018 IPR013148 Glycosyl hydrolase family 32, N-terminal CO689_RS02130 2d4a9ea71dcc35a5b0aadca7a7bd166c 494 Gene3D G3DSA:2.60.120.560 324 483 1.0E-31 T 28-03-2018 CO689_RS02130 2d4a9ea71dcc35a5b0aadca7a7bd166c 494 Pfam PF08244 Glycosyl hydrolases family 32 C terminal 354 479 1.2E-21 T 28-03-2018 IPR013189 Glycosyl hydrolase family 32, C-terminal CO689_RS02130 2d4a9ea71dcc35a5b0aadca7a7bd166c 494 Gene3D G3DSA:2.115.10.20 27 323 2.0E-39 T 28-03-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain CO689_RS01310 e996bedbbdc973d9ca1a0476e4d3f62f 185 Pfam PF06821 Serine hydrolase 6 172 4.8E-13 T 28-03-2018 IPR010662 Putative hydrolase RBBP9/YdeN GO:0016787 CO689_RS01310 e996bedbbdc973d9ca1a0476e4d3f62f 185 SUPERFAMILY SSF53474 2 182 3.16E-25 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CO689_RS01310 e996bedbbdc973d9ca1a0476e4d3f62f 185 Gene3D G3DSA:3.40.50.1820 3 181 5.5E-13 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CO689_RS09365 e6102ee30ba71f867e56707bc197981e 787 SUPERFAMILY SSF50249 631 709 2.66E-22 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CO689_RS09365 e6102ee30ba71f867e56707bc197981e 787 Pfam PF00575 S1 RNA binding domain 631 711 1.4E-16 T 28-03-2018 IPR003029 S1 domain GO:0003676 CO689_RS09365 e6102ee30ba71f867e56707bc197981e 787 Hamap MF_01895 Ribonuclease R [rnr]. 22 712 58.915 T 28-03-2018 IPR011805 Ribonuclease R GO:0003723|GO:0004518 CO689_RS09365 e6102ee30ba71f867e56707bc197981e 787 ProSitePatterns PS01175 Ribonuclease II family signature. 549 573 - T 28-03-2018 IPR022966 Ribonuclease II/R, conserved site CO689_RS09365 e6102ee30ba71f867e56707bc197981e 787 Gene3D G3DSA:2.40.50.140 61 130 0.037 T 28-03-2018 CO689_RS09365 e6102ee30ba71f867e56707bc197981e 787 SUPERFAMILY SSF50249 212 630 6.28E-145 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CO689_RS09365 e6102ee30ba71f867e56707bc197981e 787 TIGRFAM TIGR02063 RNase_R: ribonuclease R 1 712 5.3E-285 T 28-03-2018 IPR011805 Ribonuclease R GO:0003723|GO:0004518 CO689_RS09365 e6102ee30ba71f867e56707bc197981e 787 Gene3D G3DSA:2.40.50.140 629 713 1.9E-23 T 28-03-2018 CO689_RS09365 e6102ee30ba71f867e56707bc197981e 787 SUPERFAMILY SSF50249 130 229 3.69E-19 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CO689_RS09365 e6102ee30ba71f867e56707bc197981e 787 SMART SM00955 252 582 7.0E-172 T 28-03-2018 CO689_RS09365 e6102ee30ba71f867e56707bc197981e 787 Gene3D G3DSA:1.10.10.10 2 60 1.5E-4 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS09365 e6102ee30ba71f867e56707bc197981e 787 TIGRFAM TIGR00358 3_prime_RNase: VacB and RNase II family 3'-5' exoribonucleases 65 712 3.0E-224 T 28-03-2018 IPR004476 Ribonuclease II/ribonuclease R GO:0003723|GO:0004540|GO:0016070 CO689_RS09365 e6102ee30ba71f867e56707bc197981e 787 SUPERFAMILY SSF50249 62 133 9.86E-14 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CO689_RS09365 e6102ee30ba71f867e56707bc197981e 787 Pfam PF08206 Ribonuclease B OB domain 76 135 2.3E-17 T 28-03-2018 IPR013223 Ribonuclease B, N-terminal OB domain CO689_RS09365 e6102ee30ba71f867e56707bc197981e 787 Pfam PF08206 Ribonuclease B OB domain 154 202 1.3E-8 T 28-03-2018 IPR013223 Ribonuclease B, N-terminal OB domain CO689_RS09365 e6102ee30ba71f867e56707bc197981e 787 SMART SM00316 630 712 1.3E-16 T 28-03-2018 IPR022967 RNA-binding domain, S1 CO689_RS09365 e6102ee30ba71f867e56707bc197981e 787 Pfam PF00773 RNB domain 252 580 4.0E-114 T 28-03-2018 CO689_RS09365 e6102ee30ba71f867e56707bc197981e 787 SMART SM00357 142 206 0.0024 T 28-03-2018 IPR011129 Cold shock domain GO:0003676 CO689_RS09365 e6102ee30ba71f867e56707bc197981e 787 SMART SM00357 75 137 4.4E-7 T 28-03-2018 IPR011129 Cold shock domain GO:0003676 CO689_RS03795 45d69ed2aef7911589148687f41dae68 229 Gene3D G3DSA:3.40.50.300 2 229 5.9E-63 T 28-03-2018 CO689_RS03795 45d69ed2aef7911589148687f41dae68 229 SMART SM00382 31 225 5.0E-14 T 28-03-2018 IPR003593 AAA+ ATPase domain CO689_RS03795 45d69ed2aef7911589148687f41dae68 229 SUPERFAMILY SSF52540 3 224 3.51E-61 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CO689_RS03795 45d69ed2aef7911589148687f41dae68 229 Pfam PF00005 ABC transporter 22 170 1.7E-33 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CO689_RS05290 b105c349acb7877573c98b69668a8b3e 724 Gene3D G3DSA:3.90.550.10 1 299 1.9E-35 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CO689_RS05290 b105c349acb7877573c98b69668a8b3e 724 Pfam PF04464 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase 352 717 2.1E-130 T 28-03-2018 IPR007554 CDP-glycerol glycerophosphotransferase GO:0016020|GO:0047355 CO689_RS05290 b105c349acb7877573c98b69668a8b3e 724 Pfam PF00535 Glycosyl transferase family 2 5 131 1.4E-28 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CO689_RS05290 b105c349acb7877573c98b69668a8b3e 724 SUPERFAMILY SSF53448 4 196 4.64E-37 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CO689_RS05290 b105c349acb7877573c98b69668a8b3e 724 SUPERFAMILY SSF53756 458 716 5.44E-14 T 28-03-2018 CO689_RS04835 0e2035b4a31e40488b5ef978933c7f72 240 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 38 58 2.2E-7 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CO689_RS04835 0e2035b4a31e40488b5ef978933c7f72 240 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 4 15 2.2E-7 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CO689_RS04835 0e2035b4a31e40488b5ef978933c7f72 240 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 15 28 2.2E-7 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CO689_RS04835 0e2035b4a31e40488b5ef978933c7f72 240 SUPERFAMILY SSF46955 3 111 3.08E-22 T 28-03-2018 IPR009061 Putative DNA-binding domain CO689_RS04835 0e2035b4a31e40488b5ef978933c7f72 240 Gene3D G3DSA:2.20.70.10 210 229 0.057 T 28-03-2018 CO689_RS04835 0e2035b4a31e40488b5ef978933c7f72 240 SMART SM00422 3 71 5.8E-20 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CO689_RS04835 0e2035b4a31e40488b5ef978933c7f72 240 Pfam PF13411 MerR HTH family regulatory protein 3 70 1.7E-18 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CO689_RS04835 0e2035b4a31e40488b5ef978933c7f72 240 Gene3D G3DSA:1.10.1660.10 58 143 3.7E-5 T 28-03-2018 CO689_RS04835 0e2035b4a31e40488b5ef978933c7f72 240 Gene3D G3DSA:1.10.1660.10 1 57 7.6E-20 T 28-03-2018 CO689_RS04680 b92bb8e772cf648d07a93493b11f972a 102 SUPERFAMILY SSF143430 1 83 2.09E-13 T 28-03-2018 CO689_RS04680 b92bb8e772cf648d07a93493b11f972a 102 Gene3D G3DSA:3.30.70.240 1 94 1.5E-15 T 28-03-2018 CO689_RS04680 b92bb8e772cf648d07a93493b11f972a 102 TIGRFAM TIGR01573 cas2: CRISPR-associated endonuclease Cas2 1 91 1.3E-24 T 28-03-2018 IPR021127 CRISPR-associated endonuclease Cas2 GO:0004521|GO:0043571 CO689_RS04680 b92bb8e772cf648d07a93493b11f972a 102 Hamap MF_01471 CRISPR-associated endoribonuclease Cas2 [cas2]. 1 94 14.384 T 28-03-2018 IPR021127 CRISPR-associated endonuclease Cas2 GO:0004521|GO:0043571 CO689_RS04680 b92bb8e772cf648d07a93493b11f972a 102 Pfam PF09827 CRISPR associated protein Cas2 1 80 2.5E-19 T 28-03-2018 IPR019199 Virulence-associated protein D / CRISPR associated protein Cas2 CO689_RS07510 9d811e4f572b1b81dd97258878b0eb2a 302 SUPERFAMILY SSF53850 87 299 2.52E-27 T 28-03-2018 CO689_RS07510 9d811e4f572b1b81dd97258878b0eb2a 302 Gene3D G3DSA:3.40.190.10 184 266 7.4E-9 T 28-03-2018 CO689_RS07510 9d811e4f572b1b81dd97258878b0eb2a 302 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 62 8.1E-19 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CO689_RS07510 9d811e4f572b1b81dd97258878b0eb2a 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 1.2E-8 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CO689_RS07510 9d811e4f572b1b81dd97258878b0eb2a 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 1.2E-8 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CO689_RS07510 9d811e4f572b1b81dd97258878b0eb2a 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 1.2E-8 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CO689_RS07510 9d811e4f572b1b81dd97258878b0eb2a 302 Gene3D G3DSA:3.40.190.10 88 183 2.1E-19 T 28-03-2018 CO689_RS07510 9d811e4f572b1b81dd97258878b0eb2a 302 Gene3D G3DSA:1.10.10.10 1 83 2.0E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS07510 9d811e4f572b1b81dd97258878b0eb2a 302 SUPERFAMILY SSF46785 1 110 3.56E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS07510 9d811e4f572b1b81dd97258878b0eb2a 302 Pfam PF03466 LysR substrate binding domain 88 296 1.2E-25 T 28-03-2018 IPR005119 LysR, substrate-binding CO689_RS02510 bcfbb8c573051da7a07ce79ff6d29ef5 347 TIGRFAM TIGR00057 TIGR00057: tRNA threonylcarbamoyl adenosine modification protein, Sua5/YciO/YrdC/YwlC family 15 213 6.5E-60 T 28-03-2018 IPR006070 YrdC-like domain GO:0003725 CO689_RS02510 bcfbb8c573051da7a07ce79ff6d29ef5 347 Gene3D G3DSA:3.90.870.10 5 219 5.9E-71 T 28-03-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain CO689_RS02510 bcfbb8c573051da7a07ce79ff6d29ef5 347 Pfam PF01300 Telomere recombination 28 203 1.9E-53 T 28-03-2018 IPR006070 YrdC-like domain GO:0003725 CO689_RS02510 bcfbb8c573051da7a07ce79ff6d29ef5 347 PIRSF PIRSF004930 1 344 5.7E-110 T 28-03-2018 IPR010923 tRNA threonylcarbamoyladenosine biosynthesis protein SUA5 CO689_RS02510 bcfbb8c573051da7a07ce79ff6d29ef5 347 SUPERFAMILY SSF55821 17 210 2.38E-62 T 28-03-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain CO689_RS02510 bcfbb8c573051da7a07ce79ff6d29ef5 347 Pfam PF03481 Putative GTP-binding controlling metal-binding 205 338 2.5E-18 T 28-03-2018 IPR005145 Putative GTP-binding controlling metal-binding domain CO689_RS12810 416f017d43b4c75037984ef3bd2b524d 436 SUPERFAMILY SSF52540 5 165 7.1E-45 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CO689_RS12810 416f017d43b4c75037984ef3bd2b524d 436 Pfam PF01926 50S ribosome-binding GTPase 6 120 3.7E-26 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CO689_RS12810 416f017d43b4c75037984ef3bd2b524d 436 Pfam PF01926 50S ribosome-binding GTPase 178 295 1.8E-26 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CO689_RS12810 416f017d43b4c75037984ef3bd2b524d 436 Gene3D G3DSA:1.20.120.430 242 359 3.4E-15 T 28-03-2018 CO689_RS12810 416f017d43b4c75037984ef3bd2b524d 436 Gene3D G3DSA:1.20.120.430 1 68 7.9E-18 T 28-03-2018 CO689_RS12810 416f017d43b4c75037984ef3bd2b524d 436 Hamap MF_00195 GTPase Der [der]. 3 436 41.334 T 28-03-2018 IPR016484 GTP-binding protein EngA GO:0005525 CO689_RS12810 416f017d43b4c75037984ef3bd2b524d 436 SUPERFAMILY SSF52540 138 435 8.33E-73 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CO689_RS12810 416f017d43b4c75037984ef3bd2b524d 436 Gene3D G3DSA:1.20.120.430 69 241 1.6E-45 T 28-03-2018 CO689_RS12810 416f017d43b4c75037984ef3bd2b524d 436 Pfam PF14714 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal 353 432 5.1E-34 T 28-03-2018 IPR032859 GTPase Der, C-terminal KH-domain-like CO689_RS12810 416f017d43b4c75037984ef3bd2b524d 436 PIRSF PIRSF006485 2 436 2.5E-178 T 28-03-2018 IPR016484 GTP-binding protein EngA GO:0005525 CO689_RS12810 416f017d43b4c75037984ef3bd2b524d 436 TIGRFAM TIGR03594 GTPase_EngA: ribosome-associated GTPase EngA 4 431 1.5E-182 T 28-03-2018 IPR016484 GTP-binding protein EngA GO:0005525 CO689_RS12810 416f017d43b4c75037984ef3bd2b524d 436 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 248 266 7.2E-6 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CO689_RS12810 416f017d43b4c75037984ef3bd2b524d 436 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 178 198 7.2E-6 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CO689_RS12810 416f017d43b4c75037984ef3bd2b524d 436 Gene3D G3DSA:3.30.300.20 360 434 2.4E-36 T 28-03-2018 IPR015946 K homology domain-like, alpha/beta CO689_RS12810 416f017d43b4c75037984ef3bd2b524d 436 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 2 148 6.8E-25 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 CO689_RS12810 416f017d43b4c75037984ef3bd2b524d 436 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 175 342 3.4E-25 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 CO689_RS12905 e1173f615154e6daebeff275c9bfb749 302 SUPERFAMILY SSF51430 1 278 3.54E-66 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CO689_RS12905 e1173f615154e6daebeff275c9bfb749 302 Pfam PF00248 Aldo/keto reductase family 14 277 5.1E-52 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CO689_RS12905 e1173f615154e6daebeff275c9bfb749 302 Gene3D G3DSA:3.20.20.100 1 301 2.8E-65 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CO689_RS04830 3929aa6b471329e7bfcde293fc70fa7b 308 Gene3D G3DSA:3.40.50.300 2 263 3.8E-62 T 28-03-2018 CO689_RS04830 3929aa6b471329e7bfcde293fc70fa7b 308 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CO689_RS04830 3929aa6b471329e7bfcde293fc70fa7b 308 Pfam PF00005 ABC transporter 19 162 1.0E-28 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CO689_RS04830 3929aa6b471329e7bfcde293fc70fa7b 308 SMART SM00382 27 211 1.1E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain CO689_RS04830 3929aa6b471329e7bfcde293fc70fa7b 308 SUPERFAMILY SSF52540 3 224 5.98E-61 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CO689_RS04395 c3df11418e10adec7ca44b1b633fba02 108 Pfam PF05437 Branched-chain amino acid transport protein (AzlD) 7 103 6.6E-24 T 28-03-2018 IPR008407 Branched-chain amino acid transport, AzlD CO689_RS04395 c3df11418e10adec7ca44b1b633fba02 108 PIRSF PIRSF003203 1 108 3.8E-38 T 28-03-2018 IPR008407 Branched-chain amino acid transport, AzlD CO689_RS04445 2fffbd85e6a78d7fed3938ace2ae0ecb 226 Pfam PF00005 ABC transporter 21 169 2.9E-33 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CO689_RS04445 2fffbd85e6a78d7fed3938ace2ae0ecb 226 SMART SM00382 30 218 9.0E-16 T 28-03-2018 IPR003593 AAA+ ATPase domain CO689_RS04445 2fffbd85e6a78d7fed3938ace2ae0ecb 226 ProSitePatterns PS00211 ABC transporters family signature. 142 156 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CO689_RS04445 2fffbd85e6a78d7fed3938ace2ae0ecb 226 SUPERFAMILY SSF52540 1 222 3.4E-73 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CO689_RS04445 2fffbd85e6a78d7fed3938ace2ae0ecb 226 Gene3D G3DSA:3.40.50.300 1 226 1.6E-62 T 28-03-2018 CO689_RS06415 e65f0c15895825cfe1fbe7e82b8791a0 293 Pfam PF00701 Dihydrodipicolinate synthetase family 5 289 2.6E-85 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CO689_RS06415 e65f0c15895825cfe1fbe7e82b8791a0 293 ProSitePatterns PS00666 Dihydrodipicolinate synthase signature 2. 137 167 - T 28-03-2018 IPR020625 Schiff base-forming aldolase, active site GO:0008152|GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|Reactome: R-HSA-389661 CO689_RS06415 e65f0c15895825cfe1fbe7e82b8791a0 293 Gene3D G3DSA:3.20.20.70 2 293 7.8E-71 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CO689_RS06415 e65f0c15895825cfe1fbe7e82b8791a0 293 PRINTS PR00146 Dihydrodipicolinate synthase signature 75 93 2.7E-17 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CO689_RS06415 e65f0c15895825cfe1fbe7e82b8791a0 293 PRINTS PR00146 Dihydrodipicolinate synthase signature 39 60 2.7E-17 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CO689_RS06415 e65f0c15895825cfe1fbe7e82b8791a0 293 PRINTS PR00146 Dihydrodipicolinate synthase signature 107 123 2.7E-17 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CO689_RS06415 e65f0c15895825cfe1fbe7e82b8791a0 293 PRINTS PR00146 Dihydrodipicolinate synthase signature 132 149 2.7E-17 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CO689_RS06415 e65f0c15895825cfe1fbe7e82b8791a0 293 SUPERFAMILY SSF51569 4 292 1.78E-75 T 28-03-2018 CO689_RS06415 e65f0c15895825cfe1fbe7e82b8791a0 293 Hamap MF_01237 N-acetylneuraminate lyase [nanA]. 5 293 50.631 T 28-03-2018 IPR005264 N-acetylneuraminate lyase GO:0005737|GO:0005975|GO:0008747 KEGG: 00520+4.1.3.3|MetaCyc: PWY-7581|Reactome: R-HSA-4085001 CO689_RS06415 e65f0c15895825cfe1fbe7e82b8791a0 293 PIRSF PIRSF001365 1 293 2.1E-59 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CO689_RS06415 e65f0c15895825cfe1fbe7e82b8791a0 293 SMART SM01130 4 292 3.0E-71 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CO689_RS10340 6c3f6b1f60eccae6495ab250f2cb6a6d 271 SUPERFAMILY SSF103473 11 256 5.75E-10 T 28-03-2018 IPR020846 Major facilitator superfamily domain CO689_RS10340 6c3f6b1f60eccae6495ab250f2cb6a6d 271 Gene3D G3DSA:1.20.1250.20 137 271 0.018 T 28-03-2018 CO689_RS10340 6c3f6b1f60eccae6495ab250f2cb6a6d 271 TIGRFAM TIGR03716 R_switched_YkoY: integral membrane protein, YkoY family 12 258 2.3E-90 T 28-03-2018 IPR022493 Integral membrane YkoY CO689_RS10340 6c3f6b1f60eccae6495ab250f2cb6a6d 271 Gene3D G3DSA:1.20.1250.20 4 98 0.011 T 28-03-2018 CO689_RS10340 6c3f6b1f60eccae6495ab250f2cb6a6d 271 Pfam PF03741 Integral membrane protein TerC family 15 217 3.2E-52 T 28-03-2018 IPR005496 Integral membrane protein TerC GO:0016021 CO689_RS08300 3870b776abbe43da8195b946a9c76aca 331 Pfam PF00288 GHMP kinases N terminal domain 92 148 2.9E-7 T 28-03-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 CO689_RS08300 3870b776abbe43da8195b946a9c76aca 331 TIGRFAM TIGR01240 mevDPdecarb: diphosphomevalonate decarboxylase 6 308 6.8E-121 T 28-03-2018 IPR029765 Diphosphomevalonate decarboxylase GO:0004163|GO:0005829|GO:0019287 KEGG: 00900+4.1.1.33|MetaCyc: PWY-7391|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-2426168|Reactome: R-HSA-446199 CO689_RS08300 3870b776abbe43da8195b946a9c76aca 331 SUPERFAMILY SSF55060 176 327 1.44E-44 T 28-03-2018 IPR013750 GHMP kinase, C-terminal domain CO689_RS08300 3870b776abbe43da8195b946a9c76aca 331 Gene3D G3DSA:3.30.70.890 173 329 2.0E-45 T 28-03-2018 IPR013750 GHMP kinase, C-terminal domain CO689_RS08300 3870b776abbe43da8195b946a9c76aca 331 PIRSF PIRSF015950 1 331 1.3E-123 T 28-03-2018 IPR005935 Diphosphomevalonate/phosphomevalonate decarboxylase GO:0008299|GO:0016831 KEGG: 00900+4.1.1.33|MetaCyc: PWY-7391|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-2426168|Reactome: R-HSA-446199 CO689_RS08300 3870b776abbe43da8195b946a9c76aca 331 Pfam PF08544 GHMP kinases C terminal 221 308 1.1E-5 T 28-03-2018 IPR013750 GHMP kinase, C-terminal domain CO689_RS08300 3870b776abbe43da8195b946a9c76aca 331 SUPERFAMILY SSF54211 3 168 1.37E-40 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CO689_RS08300 3870b776abbe43da8195b946a9c76aca 331 Gene3D G3DSA:3.30.230.10 2 172 1.5E-60 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CO689_RS12120 85a33d89adbcb8e69337637b2ce749b6 49 TIGRFAM TIGR01023 rpmG_bact: ribosomal protein bL33 3 49 5.2E-22 T 28-03-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CO689_RS12120 85a33d89adbcb8e69337637b2ce749b6 49 Hamap MF_00294 50S ribosomal protein L33 [rpmG]. 1 49 19.951 T 28-03-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CO689_RS12120 85a33d89adbcb8e69337637b2ce749b6 49 ProSitePatterns PS00582 Ribosomal protein L33 signature. 17 36 - T 28-03-2018 IPR018264 Ribosomal protein L33, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CO689_RS12120 85a33d89adbcb8e69337637b2ce749b6 49 Pfam PF00471 Ribosomal protein L33 3 49 9.9E-25 T 28-03-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CO689_RS12120 85a33d89adbcb8e69337637b2ce749b6 49 SUPERFAMILY SSF57829 2 49 2.01E-20 T 28-03-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 CO689_RS08380 d77afec96d0ffeddaaf122e6509e3210 124 SUPERFAMILY SSF46785 11 114 6.67E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS08380 d77afec96d0ffeddaaf122e6509e3210 124 Gene3D G3DSA:1.10.10.10 9 123 1.4E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS08380 d77afec96d0ffeddaaf122e6509e3210 124 TIGRFAM TIGR01889 Staph_reg_Sar: staphylococcal accessory regulator family 11 115 1.0E-33 T 28-03-2018 IPR010166 Transcriptional regulator SarA/Rot GO:0006355 CO689_RS02580 ce1829edb63411ea5ab5c46b9a5930aa 121 Gene3D G3DSA:3.10.180.10 1 118 3.9E-17 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CO689_RS02580 ce1829edb63411ea5ab5c46b9a5930aa 121 Pfam PF06983 3-demethylubiquinone-9 3-methyltransferase 6 114 1.2E-6 T 28-03-2018 IPR028973 PhnB-like CO689_RS02580 ce1829edb63411ea5ab5c46b9a5930aa 121 SUPERFAMILY SSF54593 1 115 3.1E-23 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CO689_RS11965 847d9473568965f9775c2d1c0e0616de 649 SUPERFAMILY SSF118116 459 647 1.23E-53 T 28-03-2018 CO689_RS11965 847d9473568965f9775c2d1c0e0616de 649 Pfam PF13589 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 26 120 3.0E-13 T 28-03-2018 CO689_RS11965 847d9473568965f9775c2d1c0e0616de 649 Pfam PF01119 DNA mismatch repair protein, C-terminal domain 209 325 4.9E-38 T 28-03-2018 IPR013507 DNA mismatch repair protein, C-terminal GO:0005524|GO:0006298|GO:0030983 CO689_RS11965 847d9473568965f9775c2d1c0e0616de 649 SUPERFAMILY SSF55874 3 213 1.7E-50 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CO689_RS11965 847d9473568965f9775c2d1c0e0616de 649 ProSitePatterns PS00058 DNA mismatch repair proteins mutL / hexB / PMS1 signature. 94 100 - T 28-03-2018 IPR014762 DNA mismatch repair, conserved site CO689_RS11965 847d9473568965f9775c2d1c0e0616de 649 Gene3D G3DSA:3.30.230.10 213 325 8.6E-31 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CO689_RS11965 847d9473568965f9775c2d1c0e0616de 649 TIGRFAM TIGR00585 mutl: DNA mismatch repair protein MutL 3 306 1.2E-100 T 28-03-2018 IPR002099 DNA mismatch repair protein family GO:0005524|GO:0006298|GO:0030983 CO689_RS11965 847d9473568965f9775c2d1c0e0616de 649 Pfam PF08676 MutL C terminal dimerisation domain 462 605 2.0E-46 T 28-03-2018 IPR014790 MutL, C-terminal, dimerisation GO:0005524|GO:0006298 CO689_RS11965 847d9473568965f9775c2d1c0e0616de 649 Gene3D G3DSA:3.30.565.10 2 211 1.2E-33 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CO689_RS11965 847d9473568965f9775c2d1c0e0616de 649 SUPERFAMILY SSF54211 190 326 6.45E-38 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CO689_RS11965 847d9473568965f9775c2d1c0e0616de 649 SMART SM00853 463 605 4.6E-51 T 28-03-2018 IPR014790 MutL, C-terminal, dimerisation GO:0005524|GO:0006298 CO689_RS11965 847d9473568965f9775c2d1c0e0616de 649 Hamap MF_00149 DNA mismatch repair protein MutL [mutL]. 2 645 27.358 T 28-03-2018 IPR020667 DNA mismatch repair protein, MutL GO:0006298 CO689_RS11965 847d9473568965f9775c2d1c0e0616de 649 SMART SM01340 208 326 4.0E-56 T 28-03-2018 IPR013507 DNA mismatch repair protein, C-terminal GO:0005524|GO:0006298|GO:0030983 CO689_RS09190 6a08a6e1833664427d2b3c279df4824c 438 Gene3D G3DSA:1.10.10.10 108 153 0.0017 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS09190 6a08a6e1833664427d2b3c279df4824c 438 Pfam PF13542 Helix-turn-helix domain of transposase family ISL3 98 147 1.2E-6 T 28-03-2018 IPR032877 Transposase IS204/IS1001/IS1096/IS1165, helix-turn-helix domain CO689_RS09190 6a08a6e1833664427d2b3c279df4824c 438 Pfam PF01610 Transposase 164 417 4.8E-62 T 28-03-2018 IPR002560 Transposase IS204/IS1001/IS1096/IS1165, DDE domain CO689_RS09190 6a08a6e1833664427d2b3c279df4824c 438 Pfam PF14690 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 43 92 1.0E-5 T 28-03-2018 IPR029261 Transposase IS204/IS1001/IS1096/IS1165, zinc-finger CO689_RS00840 6a08a6e1833664427d2b3c279df4824c 438 Gene3D G3DSA:1.10.10.10 108 153 0.0017 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS00840 6a08a6e1833664427d2b3c279df4824c 438 Pfam PF13542 Helix-turn-helix domain of transposase family ISL3 98 147 1.2E-6 T 28-03-2018 IPR032877 Transposase IS204/IS1001/IS1096/IS1165, helix-turn-helix domain CO689_RS00840 6a08a6e1833664427d2b3c279df4824c 438 Pfam PF01610 Transposase 164 417 4.8E-62 T 28-03-2018 IPR002560 Transposase IS204/IS1001/IS1096/IS1165, DDE domain CO689_RS00840 6a08a6e1833664427d2b3c279df4824c 438 Pfam PF14690 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 43 92 1.0E-5 T 28-03-2018 IPR029261 Transposase IS204/IS1001/IS1096/IS1165, zinc-finger CO689_RS12005 6a08a6e1833664427d2b3c279df4824c 438 Gene3D G3DSA:1.10.10.10 108 153 0.0017 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS12005 6a08a6e1833664427d2b3c279df4824c 438 Pfam PF13542 Helix-turn-helix domain of transposase family ISL3 98 147 1.2E-6 T 28-03-2018 IPR032877 Transposase IS204/IS1001/IS1096/IS1165, helix-turn-helix domain CO689_RS12005 6a08a6e1833664427d2b3c279df4824c 438 Pfam PF01610 Transposase 164 417 4.8E-62 T 28-03-2018 IPR002560 Transposase IS204/IS1001/IS1096/IS1165, DDE domain CO689_RS12005 6a08a6e1833664427d2b3c279df4824c 438 Pfam PF14690 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 43 92 1.0E-5 T 28-03-2018 IPR029261 Transposase IS204/IS1001/IS1096/IS1165, zinc-finger CO689_RS07780 9a57e1873882d6566c38ba610805dc76 295 SUPERFAMILY SSF118352 233 291 5.1E-20 T 28-03-2018 IPR016154 Heat shock protein Hsp33, C-terminal GO:0005737|GO:0006457|GO:0051082 CO689_RS07780 9a57e1873882d6566c38ba610805dc76 295 Gene3D G3DSA:3.90.1280.10 236 289 1.7E-22 T 28-03-2018 IPR016154 Heat shock protein Hsp33, C-terminal GO:0005737|GO:0006457|GO:0051082 CO689_RS07780 9a57e1873882d6566c38ba610805dc76 295 Pfam PF01430 Hsp33 protein 4 280 1.1E-89 T 28-03-2018 IPR000397 Heat shock protein Hsp33 GO:0005737|GO:0006457|GO:0051082 CO689_RS07780 9a57e1873882d6566c38ba610805dc76 295 Hamap MF_00117 33 kDa chaperonin [hslO]. 3 292 39.87 T 28-03-2018 IPR000397 Heat shock protein Hsp33 GO:0005737|GO:0006457|GO:0051082 CO689_RS07780 9a57e1873882d6566c38ba610805dc76 295 PIRSF PIRSF005261 1 293 1.0E-74 T 28-03-2018 IPR000397 Heat shock protein Hsp33 GO:0005737|GO:0006457|GO:0051082 CO689_RS07780 9a57e1873882d6566c38ba610805dc76 295 SUPERFAMILY SSF64397 3 241 9.94E-77 T 28-03-2018 IPR016153 Heat shock protein Hsp33, N-terminal GO:0005737|GO:0006457|GO:0051082 CO689_RS07780 9a57e1873882d6566c38ba610805dc76 295 Gene3D G3DSA:3.55.30.10 3 235 7.8E-78 T 28-03-2018 IPR016153 Heat shock protein Hsp33, N-terminal GO:0005737|GO:0006457|GO:0051082 CO689_RS04465 fafd1fa1d8a0d00a71f704fb7ddcad26 170 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 78 162 2.4E-29 T 28-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 CO689_RS04465 fafd1fa1d8a0d00a71f704fb7ddcad26 170 Hamap MF_00772 Methylated-DNA--protein-cysteine methyltransferase [ogt]. 6 162 34.508 T 28-03-2018 IPR023546 Methylated-DNA--protein-cysteine methyltransferase GO:0003824|GO:0006281 CO689_RS04465 fafd1fa1d8a0d00a71f704fb7ddcad26 170 TIGRFAM TIGR00589 ogt: methylated-DNA--[protein]-cysteine S-methyltransferase 77 161 6.3E-29 T 28-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 CO689_RS04465 fafd1fa1d8a0d00a71f704fb7ddcad26 170 Gene3D G3DSA:1.10.10.10 73 164 2.1E-32 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS04465 fafd1fa1d8a0d00a71f704fb7ddcad26 170 SUPERFAMILY SSF53155 5 81 1.1E-13 T 28-03-2018 IPR008332 Methylguanine DNA methyltransferase, ribonuclease-like domain GO:0003908|GO:0006281 Reactome: R-HSA-5657655 CO689_RS04465 fafd1fa1d8a0d00a71f704fb7ddcad26 170 ProSitePatterns PS00374 Methylated-DNA--protein-cysteine methyltransferase active site. 132 138 - T 28-03-2018 IPR001497 Methylated-DNA-[protein]-cysteine S-methyltransferase, active site GO:0003908|GO:0006281 Reactome: R-HSA-5657655 CO689_RS04465 fafd1fa1d8a0d00a71f704fb7ddcad26 170 SUPERFAMILY SSF46767 76 162 3.14E-27 T 28-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 CO689_RS04465 fafd1fa1d8a0d00a71f704fb7ddcad26 170 Gene3D G3DSA:3.30.160.70 1 72 2.7E-14 T 28-03-2018 CO689_RS04320 548c349cadf48ff2532f7eb42b546e5d 311 Gene3D G3DSA:3.40.50.1980 1 116 6.9E-27 T 28-03-2018 CO689_RS04320 548c349cadf48ff2532f7eb42b546e5d 311 Pfam PF01297 Zinc-uptake complex component A periplasmic 3 308 4.2E-61 T 28-03-2018 IPR006127 Periplasmic solute binding protein, ZnuA-like GO:0030001|GO:0046872 CO689_RS04320 548c349cadf48ff2532f7eb42b546e5d 311 Gene3D G3DSA:3.40.50.1980 190 310 4.3E-27 T 28-03-2018 CO689_RS04320 548c349cadf48ff2532f7eb42b546e5d 311 SUPERFAMILY SSF53807 2 309 6.87E-70 T 28-03-2018 CO689_RS04320 548c349cadf48ff2532f7eb42b546e5d 311 Gene3D G3DSA:3.40.50.1980 117 189 4.5E-20 T 28-03-2018 CO689_RS01945 5dfab0e5d048e401575c638ad501c3ba 242 Pfam PF12679 ABC-2 family transporter protein 46 240 1.2E-9 T 28-03-2018 IPR032688 ABC-2 family transporter protein GO:0006810 CO689_RS12255 5c7dc296e81c6cbae6486d178a20d063 286 SUPERFAMILY SSF50151 4 58 1.44E-12 T 28-03-2018 IPR004341 CAT RNA-binding domain GO:0003723 CO689_RS12255 5c7dc296e81c6cbae6486d178a20d063 286 Gene3D G3DSA:1.10.1790.10 59 172 6.7E-25 T 28-03-2018 IPR011608 PRD domain GO:0006355 CO689_RS12255 5c7dc296e81c6cbae6486d178a20d063 286 SUPERFAMILY SSF63520 60 168 6.15E-28 T 28-03-2018 IPR011608 PRD domain GO:0006355 CO689_RS12255 5c7dc296e81c6cbae6486d178a20d063 286 Pfam PF03123 CAT RNA binding domain 4 62 2.0E-20 T 28-03-2018 IPR004341 CAT RNA-binding domain GO:0003723 CO689_RS12255 5c7dc296e81c6cbae6486d178a20d063 286 ProSitePatterns PS00654 PRD domain signature. 103 115 - T 28-03-2018 IPR001550 Transcription antiterminator, conserved site GO:0003723|GO:0045893 CO689_RS12255 5c7dc296e81c6cbae6486d178a20d063 286 SUPERFAMILY SSF63520 182 276 4.32E-24 T 28-03-2018 IPR011608 PRD domain GO:0006355 CO689_RS12255 5c7dc296e81c6cbae6486d178a20d063 286 Gene3D G3DSA:2.30.24.10 1 58 2.3E-23 T 28-03-2018 IPR004341 CAT RNA-binding domain GO:0003723 CO689_RS12255 5c7dc296e81c6cbae6486d178a20d063 286 Pfam PF00874 PRD domain 78 167 7.5E-24 T 28-03-2018 IPR011608 PRD domain GO:0006355 CO689_RS12255 5c7dc296e81c6cbae6486d178a20d063 286 Pfam PF00874 PRD domain 186 275 9.7E-21 T 28-03-2018 IPR011608 PRD domain GO:0006355 CO689_RS12255 5c7dc296e81c6cbae6486d178a20d063 286 Gene3D G3DSA:1.10.1790.10 173 281 1.2E-20 T 28-03-2018 IPR011608 PRD domain GO:0006355 CO689_RS12255 5c7dc296e81c6cbae6486d178a20d063 286 SMART SM01061 4 64 2.6E-21 T 28-03-2018 IPR004341 CAT RNA-binding domain GO:0003723 CO689_RS01335 90378a24a16dca29910747ab41286c3a 408 PIRSF PIRSF037259 4 408 3.9E-97 T 28-03-2018 IPR010288 Bacterial ABC transporter EcsB GO:0016021 CO689_RS01335 90378a24a16dca29910747ab41286c3a 408 Pfam PF05975 Bacterial ABC transporter protein EcsB 8 387 1.3E-104 T 28-03-2018 IPR010288 Bacterial ABC transporter EcsB GO:0016021 CO689_RS13435 1142e0b7edcc2de967ab290c484cf7e0 876 Pfam PF01411 tRNA synthetases class II (A) 8 556 1.9E-207 T 28-03-2018 IPR018164 Alanyl-tRNA synthetase, class IIc, N-terminal GO:0000166|GO:0004813|GO:0005524|GO:0006419 KEGG: 00970+6.1.1.7 CO689_RS13435 1142e0b7edcc2de967ab290c484cf7e0 876 Hamap MF_00036_B Alanine--tRNA ligase [alaS]. 1 876 179.964 T 28-03-2018 IPR023033 Alanine-tRNA ligase, eukaryota/bacteria GO:0004813 KEGG: 00970+6.1.1.7 CO689_RS13435 1142e0b7edcc2de967ab290c484cf7e0 876 PRINTS PR00980 Alanyl-tRNA synthetase signature 276 292 3.6E-31 T 28-03-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 CO689_RS13435 1142e0b7edcc2de967ab290c484cf7e0 876 PRINTS PR00980 Alanyl-tRNA synthetase signature 199 210 3.6E-31 T 28-03-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 CO689_RS13435 1142e0b7edcc2de967ab290c484cf7e0 876 PRINTS PR00980 Alanyl-tRNA synthetase signature 300 313 3.6E-31 T 28-03-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 CO689_RS13435 1142e0b7edcc2de967ab290c484cf7e0 876 PRINTS PR00980 Alanyl-tRNA synthetase signature 226 239 3.6E-31 T 28-03-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 CO689_RS13435 1142e0b7edcc2de967ab290c484cf7e0 876 PRINTS PR00980 Alanyl-tRNA synthetase signature 73 84 3.6E-31 T 28-03-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 CO689_RS13435 1142e0b7edcc2de967ab290c484cf7e0 876 Gene3D G3DSA:3.30.930.10 3 242 3.6E-93 T 28-03-2018 CO689_RS13435 1142e0b7edcc2de967ab290c484cf7e0 876 Gene3D G3DSA:3.30.980.10 554 714 5.0E-47 T 28-03-2018 CO689_RS13435 1142e0b7edcc2de967ab290c484cf7e0 876 SUPERFAMILY SSF55681 5 245 1.57E-87 T 28-03-2018 CO689_RS13435 1142e0b7edcc2de967ab290c484cf7e0 876 SUPERFAMILY SSF101353 246 460 5.36E-68 T 28-03-2018 IPR018162 Alanine-tRNA ligase, class IIc, anti-codon-binding domain GO:0000166|GO:0004813|GO:0005524|GO:0005737|GO:0006419 KEGG: 00970+6.1.1.7 CO689_RS13435 1142e0b7edcc2de967ab290c484cf7e0 876 TIGRFAM TIGR00344 alaS: alanine--tRNA ligase 8 856 0.0 T 28-03-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 CO689_RS13435 1142e0b7edcc2de967ab290c484cf7e0 876 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 654 697 8.5E-18 T 28-03-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 CO689_RS13435 1142e0b7edcc2de967ab290c484cf7e0 876 Pfam PF02272 DHHA1 domain 739 873 1.4E-28 T 28-03-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 CO689_RS13435 1142e0b7edcc2de967ab290c484cf7e0 876 SUPERFAMILY SSF55186 553 707 3.01E-53 T 28-03-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain GO:0000166 CO689_RS13435 1142e0b7edcc2de967ab290c484cf7e0 876 SUPERFAMILY SSF50447 454 553 3.65E-15 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain CO689_RS13435 1142e0b7edcc2de967ab290c484cf7e0 876 SMART SM00863 654 697 3.5E-21 T 28-03-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 CO689_RS11565 e8782af6a8adc8dbb0ef65ece4a582d6 92 TIGRFAM TIGR00002 S16: ribosomal protein bS16 3 81 3.3E-33 T 28-03-2018 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CO689_RS11565 e8782af6a8adc8dbb0ef65ece4a582d6 92 Gene3D G3DSA:3.30.1320.10 2 87 3.5E-33 T 28-03-2018 IPR023803 Ribosomal protein S16 domain Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CO689_RS11565 e8782af6a8adc8dbb0ef65ece4a582d6 92 Hamap MF_00385 30S ribosomal protein S16 [rpsP]. 2 79 24.598 T 28-03-2018 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CO689_RS11565 e8782af6a8adc8dbb0ef65ece4a582d6 92 Pfam PF00886 Ribosomal protein S16 9 69 8.7E-25 T 28-03-2018 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CO689_RS11565 e8782af6a8adc8dbb0ef65ece4a582d6 92 SUPERFAMILY SSF54565 2 85 1.57E-32 T 28-03-2018 IPR023803 Ribosomal protein S16 domain Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CO689_RS13310 13d5c19bd80aa5772c16496dd3f1a42c 319 SUPERFAMILY SSF55781 71 316 3.92E-45 T 28-03-2018 IPR029016 GAF domain-like CO689_RS13310 13d5c19bd80aa5772c16496dd3f1a42c 319 Pfam PF01628 HrcA protein C terminal domain 109 313 4.2E-37 T 28-03-2018 IPR021153 Heat-inducible transcription repressor HrcA, C-terminal GO:0003677|GO:0006355 CO689_RS13310 13d5c19bd80aa5772c16496dd3f1a42c 319 SUPERFAMILY SSF46785 1 82 8.3E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS13310 13d5c19bd80aa5772c16496dd3f1a42c 319 TIGRFAM TIGR00331 hrcA: heat-inducible transcription repressor HrcA 3 317 3.2E-84 T 28-03-2018 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 CO689_RS13310 13d5c19bd80aa5772c16496dd3f1a42c 319 Gene3D G3DSA:3.30.450.40 167 319 5.3E-25 T 28-03-2018 IPR029016 GAF domain-like CO689_RS13310 13d5c19bd80aa5772c16496dd3f1a42c 319 Gene3D G3DSA:1.10.10.10 1 85 1.9E-27 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS13310 13d5c19bd80aa5772c16496dd3f1a42c 319 Hamap MF_00081 Heat-inducible transcription repressor HrcA [hrcA]. 1 319 24.895 T 28-03-2018 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 CO689_RS13310 13d5c19bd80aa5772c16496dd3f1a42c 319 Pfam PF03444 Winged helix-turn-helix transcription repressor, HrcA DNA-binding 2 59 1.3E-5 T 28-03-2018 IPR005104 Winged helix-turn-helix transcription repressor, HrcA DNA-binding domain GO:0003677|GO:0006355 CO689_RS13310 13d5c19bd80aa5772c16496dd3f1a42c 319 PIRSF PIRSF005485 1 319 1.6E-85 T 28-03-2018 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 CO689_RS05110 ca897d7d63265f4bac1dd8d8336f3de1 162 Pfam PF01899 Na+/H+ ion antiporter subunit 9 160 2.3E-30 T 28-03-2018 IPR002758 Na+/H+ antiporter subunit E GO:0006812|GO:0008324|GO:0016021 CO689_RS03980 aecd599a25e517645ee36644c8efb720 801 Gene3D G3DSA:3.50.50.60 245 315 1.9E-7 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CO689_RS03980 aecd599a25e517645ee36644c8efb720 801 SUPERFAMILY SSF55124 489 615 9.16E-24 T 28-03-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CO689_RS03980 aecd599a25e517645ee36644c8efb720 801 PRINTS PR00397 Sirohaem Fe-binding site signature 671 689 5.9E-6 T 28-03-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CO689_RS03980 aecd599a25e517645ee36644c8efb720 801 PRINTS PR00397 Sirohaem Fe-binding site signature 628 646 5.9E-6 T 28-03-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CO689_RS03980 aecd599a25e517645ee36644c8efb720 801 SUPERFAMILY SSF56014 627 796 7.72E-49 T 28-03-2018 CO689_RS03980 aecd599a25e517645ee36644c8efb720 801 Gene3D G3DSA:3.90.480.10 427 619 1.4E-13 T 28-03-2018 CO689_RS03980 aecd599a25e517645ee36644c8efb720 801 SUPERFAMILY SSF51905 3 193 4.15E-43 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CO689_RS03980 aecd599a25e517645ee36644c8efb720 801 Pfam PF04324 BFD-like [2Fe-2S] binding domain 479 529 9.9E-14 T 28-03-2018 IPR007419 BFD-like [2Fe-2S]-binding domain CO689_RS03980 aecd599a25e517645ee36644c8efb720 801 Pfam PF04324 BFD-like [2Fe-2S] binding domain 415 464 1.1E-17 T 28-03-2018 IPR007419 BFD-like [2Fe-2S]-binding domain CO689_RS03980 aecd599a25e517645ee36644c8efb720 801 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 625 760 1.5E-25 T 28-03-2018 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CO689_RS03980 aecd599a25e517645ee36644c8efb720 801 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 5 281 1.5E-54 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CO689_RS03980 aecd599a25e517645ee36644c8efb720 801 ProSitePatterns PS00365 Nitrite and sulfite reductases iron-sulfur/siroheme-binding site. 671 687 - T 28-03-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CO689_RS03980 aecd599a25e517645ee36644c8efb720 801 Gene3D G3DSA:3.50.50.60 2 124 1.9E-13 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CO689_RS03980 aecd599a25e517645ee36644c8efb720 801 Gene3D G3DSA:3.50.50.60 125 244 2.1E-28 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CO689_RS03980 aecd599a25e517645ee36644c8efb720 801 TIGRFAM TIGR02374 nitri_red_nirB: nitrite reductase [NAD(P)H], large subunit 6 789 3.2E-284 T 28-03-2018 IPR012744 Nitrite reductase [NAD(P)H] large subunit, NirB GO:0008942|GO:0042128|GO:0050660|GO:0050661|GO:0055114 CO689_RS03980 aecd599a25e517645ee36644c8efb720 801 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 6.7E-17 T 28-03-2018 CO689_RS03980 aecd599a25e517645ee36644c8efb720 801 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 102 120 6.7E-17 T 28-03-2018 CO689_RS03980 aecd599a25e517645ee36644c8efb720 801 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 257 279 6.7E-17 T 28-03-2018 CO689_RS03980 aecd599a25e517645ee36644c8efb720 801 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 147 165 6.7E-17 T 28-03-2018 CO689_RS03980 aecd599a25e517645ee36644c8efb720 801 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 232 248 6.7E-17 T 28-03-2018 CO689_RS03980 aecd599a25e517645ee36644c8efb720 801 Gene3D G3DSA:3.30.413.10 624 801 2.7E-35 T 28-03-2018 CO689_RS03980 aecd599a25e517645ee36644c8efb720 801 PIRSF PIRSF037149 1 800 0.0 T 28-03-2018 IPR017121 Nitrite reductase [NAD(P)H], large subunit GO:0042128 CO689_RS03980 aecd599a25e517645ee36644c8efb720 801 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 5 27 6.7E-11 T 28-03-2018 CO689_RS03980 aecd599a25e517645ee36644c8efb720 801 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 147 172 6.7E-11 T 28-03-2018 CO689_RS03980 aecd599a25e517645ee36644c8efb720 801 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 233 247 6.7E-11 T 28-03-2018 CO689_RS03980 aecd599a25e517645ee36644c8efb720 801 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 272 279 6.7E-11 T 28-03-2018 CO689_RS03980 aecd599a25e517645ee36644c8efb720 801 SUPERFAMILY SSF51905 144 305 3.65E-30 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CO689_RS03980 aecd599a25e517645ee36644c8efb720 801 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 554 615 2.1E-11 T 28-03-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CO689_RS13405 0e3506586a9c20ed63343fb45215b0fe 423 Pfam PF01136 Peptidase family U32 90 322 1.0E-85 T 28-03-2018 IPR001539 Peptidase U32 GO:0006508|GO:0008233 CO689_RS13405 0e3506586a9c20ed63343fb45215b0fe 423 Pfam PF16325 Peptidase family U32 C-terminal domain 339 419 6.6E-26 T 28-03-2018 IPR032525 Peptidase family U32, C-terminal CO689_RS13405 0e3506586a9c20ed63343fb45215b0fe 423 Gene3D G3DSA:3.20.20.70 15 291 2.6E-7 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CO689_RS13405 0e3506586a9c20ed63343fb45215b0fe 423 ProSitePatterns PS01276 Peptidase family U32 signature. 176 194 - T 28-03-2018 IPR001539 Peptidase U32 GO:0006508|GO:0008233 CO689_RS09335 1c310325cdfbdb3f13469a3841788af1 253 ProSitePatterns PS00171 Triosephosphate isomerase active site. 167 177 - T 28-03-2018 IPR020861 Triosephosphate isomerase, active site GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CO689_RS09335 1c310325cdfbdb3f13469a3841788af1 253 SUPERFAMILY SSF51351 1 250 1.31E-90 T 28-03-2018 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CO689_RS09335 1c310325cdfbdb3f13469a3841788af1 253 Gene3D G3DSA:3.20.20.70 1 253 4.8E-99 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CO689_RS09335 1c310325cdfbdb3f13469a3841788af1 253 TIGRFAM TIGR00419 tim: triose-phosphate isomerase 5 242 9.2E-57 T 28-03-2018 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CO689_RS09335 1c310325cdfbdb3f13469a3841788af1 253 Pfam PF00121 Triosephosphate isomerase 5 248 1.3E-91 T 28-03-2018 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CO689_RS09335 1c310325cdfbdb3f13469a3841788af1 253 Hamap MF_00147_B Triosephosphate isomerase [tpiA]. 2 252 41.151 T 28-03-2018 IPR022896 Triosephosphate isomerase, bacterial/eukaryotic GO:0004807|GO:0006096 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CO689_RS02150 70d45e63c3e48ce7de5bd0794bab21fc 641 ProSitePatterns PS00211 ABC transporters family signature. 167 181 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CO689_RS02150 70d45e63c3e48ce7de5bd0794bab21fc 641 ProSitePatterns PS00211 ABC transporters family signature. 447 461 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CO689_RS02150 70d45e63c3e48ce7de5bd0794bab21fc 641 SUPERFAMILY SSF52540 319 535 1.85E-39 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CO689_RS02150 70d45e63c3e48ce7de5bd0794bab21fc 641 SMART SM00382 28 247 1.7E-9 T 28-03-2018 IPR003593 AAA+ ATPase domain CO689_RS02150 70d45e63c3e48ce7de5bd0794bab21fc 641 SMART SM00382 354 520 9.4E-13 T 28-03-2018 IPR003593 AAA+ ATPase domain CO689_RS02150 70d45e63c3e48ce7de5bd0794bab21fc 641 Pfam PF16326 ABC transporter C-terminal domain 574 638 2.3E-14 T 28-03-2018 IPR032524 ABC transporter Uup, C-terminal GO:0003677 CO689_RS02150 70d45e63c3e48ce7de5bd0794bab21fc 641 Pfam PF00005 ABC transporter 347 475 3.6E-18 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CO689_RS02150 70d45e63c3e48ce7de5bd0794bab21fc 641 Pfam PF00005 ABC transporter 20 195 2.3E-27 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CO689_RS02150 70d45e63c3e48ce7de5bd0794bab21fc 641 SUPERFAMILY SSF52540 4 248 1.75E-48 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CO689_RS02150 70d45e63c3e48ce7de5bd0794bab21fc 641 Pfam PF12848 ABC transporter 238 320 1.5E-21 T 28-03-2018 IPR032781 ABC-transporter extension domain CO689_RS02150 70d45e63c3e48ce7de5bd0794bab21fc 641 Gene3D G3DSA:3.40.50.300 4 296 9.0E-56 T 28-03-2018 CO689_RS02150 70d45e63c3e48ce7de5bd0794bab21fc 641 Gene3D G3DSA:1.20.58.410 578 640 1.5E-9 T 28-03-2018 CO689_RS02150 70d45e63c3e48ce7de5bd0794bab21fc 641 Gene3D G3DSA:3.40.50.300 330 577 1.6E-51 T 28-03-2018 CO689_RS06445 4be539383f9a62ed654a95718feb534d 452 Pfam PF00324 Amino acid permease 9 448 5.4E-40 T 28-03-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0006810|GO:0016020|GO:0055085 CO689_RS06445 4be539383f9a62ed654a95718feb534d 452 PIRSF PIRSF006060 1 452 2.0E-51 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CO689_RS10890 ddad9e0944e14e3e5aef947aadc7d976 359 SMART SM00382 28 211 8.1E-16 T 28-03-2018 IPR003593 AAA+ ATPase domain CO689_RS10890 ddad9e0944e14e3e5aef947aadc7d976 359 Gene3D G3DSA:3.40.50.300 1 245 3.2E-70 T 28-03-2018 CO689_RS10890 ddad9e0944e14e3e5aef947aadc7d976 359 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CO689_RS10890 ddad9e0944e14e3e5aef947aadc7d976 359 SUPERFAMILY SSF50331 236 341 8.08E-15 T 28-03-2018 IPR008995 Molybdate/tungstate binding, C-terminal CO689_RS10890 ddad9e0944e14e3e5aef947aadc7d976 359 Pfam PF08402 TOBE domain 272 340 1.3E-9 T 28-03-2018 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 CO689_RS10890 ddad9e0944e14e3e5aef947aadc7d976 359 TIGRFAM TIGR01187 potA: polyamine ABC transporter, ATP-binding protein 34 324 1.3E-108 T 28-03-2018 IPR005893 Spermidine/putrescine ABC transporter, ATP-binding subunit GO:0015417|GO:0015846|GO:0043190 CO689_RS10890 ddad9e0944e14e3e5aef947aadc7d976 359 SUPERFAMILY SSF52540 4 243 1.2E-80 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CO689_RS10890 ddad9e0944e14e3e5aef947aadc7d976 359 Pfam PF00005 ABC transporter 19 160 1.7E-34 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CO689_RS13190 815bd17ca58a73e3ffb8bd2bb056daea 446 SMART SM00487 24 222 2.5E-45 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CO689_RS13190 815bd17ca58a73e3ffb8bd2bb056daea 446 Gene3D G3DSA:3.40.50.300 5 220 2.8E-45 T 28-03-2018 CO689_RS13190 815bd17ca58a73e3ffb8bd2bb056daea 446 Pfam PF00270 DEAD/DEAH box helicase 29 192 3.4E-38 T 28-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CO689_RS13190 815bd17ca58a73e3ffb8bd2bb056daea 446 Hamap MF_01494 DEAD-box ATP-dependent RNA helicase CshB [cshB]. 5 438 45.928 T 28-03-2018 IPR030881 DEAD-box ATP-dependent RNA helicase CshB GO:0004386|GO:0009409 CO689_RS13190 815bd17ca58a73e3ffb8bd2bb056daea 446 SMART SM00490 258 339 2.1E-28 T 28-03-2018 IPR001650 Helicase, C-terminal CO689_RS13190 815bd17ca58a73e3ffb8bd2bb056daea 446 SUPERFAMILY SSF52540 73 360 2.05E-60 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CO689_RS13190 815bd17ca58a73e3ffb8bd2bb056daea 446 Pfam PF00271 Helicase conserved C-terminal domain 234 338 1.4E-25 T 28-03-2018 IPR001650 Helicase, C-terminal CO689_RS13190 815bd17ca58a73e3ffb8bd2bb056daea 446 Gene3D G3DSA:3.40.50.300 221 446 2.2E-42 T 28-03-2018 CO689_RS06810 55da62b3638391a056fde58758acd32a 444 Gene3D G3DSA:1.20.5.40 119 146 1.0E-4 T 28-03-2018 CO689_RS06810 55da62b3638391a056fde58758acd32a 444 SMART SM00857 4 148 8.9E-42 T 28-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CO689_RS06810 55da62b3638391a056fde58758acd32a 444 Pfam PF00239 Resolvase, N terminal domain 4 147 1.6E-35 T 28-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CO689_RS06810 55da62b3638391a056fde58758acd32a 444 SUPERFAMILY SSF53041 4 147 8.24E-31 T 28-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CO689_RS06810 55da62b3638391a056fde58758acd32a 444 Gene3D G3DSA:3.30.65.10 248 323 9.4E-4 T 28-03-2018 CO689_RS06810 55da62b3638391a056fde58758acd32a 444 Gene3D G3DSA:3.40.50.1390 1 118 1.5E-28 T 28-03-2018 CO689_RS06810 55da62b3638391a056fde58758acd32a 444 Pfam PF13408 Recombinase zinc beta ribbon domain 261 321 6.4E-10 T 28-03-2018 IPR025827 Recombinase zinc beta ribbon domain CO689_RS06810 55da62b3638391a056fde58758acd32a 444 Pfam PF07508 Recombinase 168 248 2.5E-11 T 28-03-2018 IPR011109 DNA-binding recombinase domain GO:0000150|GO:0003677 CO689_RS05670 24a6907092a5272d16c213f4f8d484f8 678 Pfam PF13476 AAA domain 5 280 2.2E-10 T 28-03-2018 CO689_RS05670 24a6907092a5272d16c213f4f8d484f8 678 SUPERFAMILY SSF52540 1 56 6.52E-12 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CO689_RS05670 24a6907092a5272d16c213f4f8d484f8 678 SUPERFAMILY SSF52540 430 626 6.52E-12 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CO689_RS05670 24a6907092a5272d16c213f4f8d484f8 678 SUPERFAMILY SSF52540 1 298 5.1E-12 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CO689_RS05670 24a6907092a5272d16c213f4f8d484f8 678 Gene3D G3DSA:3.40.50.300 307 637 5.4E-6 T 28-03-2018 CO689_RS05670 24a6907092a5272d16c213f4f8d484f8 678 Gene3D G3DSA:3.40.50.300 1 197 7.6E-17 T 28-03-2018 CO689_RS11510 d60a70eb364b40bc50554e5e1c4d1ff3 684 SUPERFAMILY SSF52540 179 441 6.35E-60 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CO689_RS11510 d60a70eb364b40bc50554e5e1c4d1ff3 684 Pfam PF00270 DEAD/DEAH box helicase 264 420 2.7E-17 T 28-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CO689_RS11510 d60a70eb364b40bc50554e5e1c4d1ff3 684 SMART SM00487 259 448 7.2E-33 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CO689_RS11510 d60a70eb364b40bc50554e5e1c4d1ff3 684 SUPERFAMILY SSF50249 10 175 4.28E-29 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CO689_RS11510 d60a70eb364b40bc50554e5e1c4d1ff3 684 Pfam PF00271 Helicase conserved C-terminal domain 464 577 1.7E-20 T 28-03-2018 IPR001650 Helicase, C-terminal CO689_RS11510 d60a70eb364b40bc50554e5e1c4d1ff3 684 Gene3D G3DSA:2.40.50.140 48 144 1.7E-7 T 28-03-2018 CO689_RS11510 d60a70eb364b40bc50554e5e1c4d1ff3 684 Pfam PF17191 RecG wedge domain 16 173 2.1E-17 T 28-03-2018 IPR033454 RecG, wedge domain CO689_RS11510 d60a70eb364b40bc50554e5e1c4d1ff3 684 Gene3D G3DSA:3.40.50.300 446 618 9.1E-36 T 28-03-2018 CO689_RS11510 d60a70eb364b40bc50554e5e1c4d1ff3 684 TIGRFAM TIGR00643 recG: ATP-dependent DNA helicase RecG 30 653 3.0E-226 T 28-03-2018 IPR004609 ATP-dependent DNA helicase RecG GO:0004003|GO:0006281|GO:0006310 CO689_RS11510 d60a70eb364b40bc50554e5e1c4d1ff3 684 SMART SM00490 494 578 5.7E-23 T 28-03-2018 IPR001650 Helicase, C-terminal CO689_RS11510 d60a70eb364b40bc50554e5e1c4d1ff3 684 SUPERFAMILY SSF52540 374 634 3.59E-43 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CO689_RS11510 d60a70eb364b40bc50554e5e1c4d1ff3 684 Gene3D G3DSA:3.40.50.300 245 445 1.8E-37 T 28-03-2018 CO689_RS13510 2a460603f3ab2cdce78c50cbf00b531f 729 Gene3D G3DSA:3.30.70.260 649 729 1.1E-7 T 28-03-2018 CO689_RS13510 2a460603f3ab2cdce78c50cbf00b531f 729 Pfam PF13291 ACT domain 649 726 1.6E-17 T 28-03-2018 IPR002912 ACT domain CO689_RS13510 2a460603f3ab2cdce78c50cbf00b531f 729 Pfam PF13328 HD domain 34 180 1.4E-45 T 28-03-2018 IPR003607 HD/PDEase domain CO689_RS13510 2a460603f3ab2cdce78c50cbf00b531f 729 SUPERFAMILY SSF109604 9 195 5.96E-73 T 28-03-2018 CO689_RS13510 2a460603f3ab2cdce78c50cbf00b531f 729 SUPERFAMILY SSF55021 650 728 1.97E-7 T 28-03-2018 CO689_RS13510 2a460603f3ab2cdce78c50cbf00b531f 729 SMART SM00954 240 350 8.0E-70 T 28-03-2018 IPR007685 RelA/SpoT GO:0015969 CO689_RS13510 2a460603f3ab2cdce78c50cbf00b531f 729 Gene3D G3DSA:3.10.20.30 389 462 7.4E-20 T 28-03-2018 IPR012675 Beta-grasp domain CO689_RS13510 2a460603f3ab2cdce78c50cbf00b531f 729 Pfam PF02824 TGS domain 395 454 7.4E-19 T 28-03-2018 IPR004095 TGS KEGG: 00970+6.1.1.3 CO689_RS13510 2a460603f3ab2cdce78c50cbf00b531f 729 TIGRFAM TIGR00691 spoT_relA: RelA/SpoT family protein 32 726 5.1E-243 T 28-03-2018 IPR004811 RelA/SpoT family GO:0015969 CO689_RS13510 2a460603f3ab2cdce78c50cbf00b531f 729 Pfam PF04607 Region found in RelA / SpoT proteins 240 350 2.0E-40 T 28-03-2018 IPR007685 RelA/SpoT GO:0015969 CO689_RS13510 2a460603f3ab2cdce78c50cbf00b531f 729 SMART SM00471 46 158 1.1E-5 T 28-03-2018 IPR003607 HD/PDEase domain CO689_RS13510 2a460603f3ab2cdce78c50cbf00b531f 729 SUPERFAMILY SSF81271 382 454 6.05E-22 T 28-03-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 CO689_RS13510 2a460603f3ab2cdce78c50cbf00b531f 729 SUPERFAMILY SSF81301 199 371 2.45E-63 T 28-03-2018 CO689_RS13510 2a460603f3ab2cdce78c50cbf00b531f 729 Gene3D G3DSA:3.30.460.10 197 330 4.3E-44 T 28-03-2018 CO689_RS02035 14f04e94c376009083e29d262503427a 267 Pfam PF09250 Bifunctional DNA primase/polymerase, N-terminal 9 152 2.1E-7 T 28-03-2018 IPR015330 DNA primase/polymerase, bifunctional, N-terminal CO689_RS02035 14f04e94c376009083e29d262503427a 267 SUPERFAMILY SSF56747 5 156 2.62E-20 T 28-03-2018 CO689_RS02035 14f04e94c376009083e29d262503427a 267 SMART SM00943 7 156 9.2E-10 T 28-03-2018 IPR015330 DNA primase/polymerase, bifunctional, N-terminal CO689_RS01920 2e444146197ee7190d249acb5629f290 227 SUPERFAMILY SSF52540 1 222 2.99E-60 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CO689_RS01920 2e444146197ee7190d249acb5629f290 227 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CO689_RS01920 2e444146197ee7190d249acb5629f290 227 Gene3D G3DSA:3.40.50.300 1 227 1.0E-59 T 28-03-2018 CO689_RS01920 2e444146197ee7190d249acb5629f290 227 Pfam PF00005 ABC transporter 22 168 1.9E-30 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CO689_RS01920 2e444146197ee7190d249acb5629f290 227 SMART SM00382 30 216 1.3E-13 T 28-03-2018 IPR003593 AAA+ ATPase domain CO689_RS13035 272cc75ee7706563077bf18e7b18171d 185 Hamap MF_00141 Elongation factor P [efp]. 1 185 50.396 T 28-03-2018 IPR011768 Translation elongation factor P GO:0003746|GO:0005737|GO:0006414 CO689_RS13035 272cc75ee7706563077bf18e7b18171d 185 ProSitePatterns PS01275 Elongation factor P signature. 150 169 - T 28-03-2018 IPR013852 Translation elongation factor P/YeiP, conserved site CO689_RS13035 272cc75ee7706563077bf18e7b18171d 185 Pfam PF09285 Elongation factor P, C-terminal 129 184 5.6E-26 T 28-03-2018 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 CO689_RS13035 272cc75ee7706563077bf18e7b18171d 185 Pfam PF08207 Elongation factor P (EF-P) KOW-like domain 3 60 1.9E-27 T 28-03-2018 IPR013185 Translation elongation factor, KOW-like CO689_RS13035 272cc75ee7706563077bf18e7b18171d 185 TIGRFAM TIGR00038 efp: translation elongation factor P 2 185 6.7E-80 T 28-03-2018 IPR011768 Translation elongation factor P GO:0003746|GO:0005737|GO:0006414 CO689_RS13035 272cc75ee7706563077bf18e7b18171d 185 PIRSF PIRSF005901 1 185 1.6E-71 T 28-03-2018 IPR020599 Translation elongation factor P/YeiP CO689_RS13035 272cc75ee7706563077bf18e7b18171d 185 SUPERFAMILY SSF50249 65 129 1.54E-20 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CO689_RS13035 272cc75ee7706563077bf18e7b18171d 185 SUPERFAMILY SSF50249 128 185 1.18E-17 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CO689_RS13035 272cc75ee7706563077bf18e7b18171d 185 Gene3D G3DSA:2.30.30.30 2 61 4.5E-27 T 28-03-2018 IPR014722 Ribosomal protein L2 domain 2 CO689_RS13035 272cc75ee7706563077bf18e7b18171d 185 Gene3D G3DSA:2.40.50.140 65 126 1.8E-24 T 28-03-2018 CO689_RS13035 272cc75ee7706563077bf18e7b18171d 185 SMART SM00841 129 184 2.5E-31 T 28-03-2018 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 CO689_RS13035 272cc75ee7706563077bf18e7b18171d 185 SUPERFAMILY SSF50104 1 63 6.62E-22 T 28-03-2018 IPR008991 Translation protein SH3-like domain CO689_RS13035 272cc75ee7706563077bf18e7b18171d 185 Gene3D G3DSA:2.40.50.140 129 184 1.1E-26 T 28-03-2018 CO689_RS13035 272cc75ee7706563077bf18e7b18171d 185 SMART SM01185 67 121 7.7E-26 T 28-03-2018 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 CO689_RS13035 272cc75ee7706563077bf18e7b18171d 185 Pfam PF01132 Elongation factor P (EF-P) OB domain 69 121 2.3E-22 T 28-03-2018 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 CO689_RS12125 fbdacfacea1c3587a33667bab07f53b3 89 Hamap MF_00537 30S ribosomal protein S14 [rpsN]. 1 89 25.241 T 28-03-2018 IPR023036 Ribosomal protein S14, bacterial/plastid CO689_RS12125 fbdacfacea1c3587a33667bab07f53b3 89 Gene3D G3DSA:4.10.830.10 1 89 1.6E-35 T 28-03-2018 CO689_RS12125 fbdacfacea1c3587a33667bab07f53b3 89 ProSitePatterns PS00527 Ribosomal protein S14 signature. 50 73 - T 28-03-2018 IPR018271 Ribosomal protein S14, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CO689_RS12125 fbdacfacea1c3587a33667bab07f53b3 89 SUPERFAMILY SSF57716 2 89 4.49E-32 T 28-03-2018 CO689_RS12125 fbdacfacea1c3587a33667bab07f53b3 89 Pfam PF00253 Ribosomal protein S14p/S29e 36 88 4.8E-28 T 28-03-2018 IPR001209 Ribosomal protein S14 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CO689_RS02950 9e8b5134625da49e6e5a0c8f0d3c1764 174 SUPERFAMILY SSF109854 5 170 1.27E-33 T 28-03-2018 IPR034660 DinB/YfiT-like putative metalloenzymes CO689_RS02950 9e8b5134625da49e6e5a0c8f0d3c1764 174 Pfam PF12867 DinB superfamily 29 164 2.3E-8 T 28-03-2018 IPR024775 DinB-like domain CO689_RS02950 9e8b5134625da49e6e5a0c8f0d3c1764 174 Gene3D G3DSA:1.20.120.450 1 172 6.8E-24 T 28-03-2018 CO689_RS11890 485532eeb83a4fb7dbf06a26e3b946ca 591 SUPERFAMILY SSF52922 473 581 3.14E-19 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CO689_RS11890 485532eeb83a4fb7dbf06a26e3b946ca 591 TIGRFAM TIGR03710 OAFO_sf: 2-oxoacid:acceptor oxidoreductase, alpha subunit 4 574 7.1E-211 T 28-03-2018 IPR022367 2-oxoacid:acceptor oxidoreductase, alpha subunit KEGG: 00020+1.2.7.3|KEGG: 00720+1.2.7.3|MetaCyc: PWY-5392|MetaCyc: PWY-6969 CO689_RS11890 485532eeb83a4fb7dbf06a26e3b946ca 591 Gene3D G3DSA:3.40.50.920 487 566 2.2E-8 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CO689_RS11890 485532eeb83a4fb7dbf06a26e3b946ca 591 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 210 452 2.0E-62 T 28-03-2018 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 CO689_RS11890 485532eeb83a4fb7dbf06a26e3b946ca 591 SUPERFAMILY SSF52518 198 459 3.27E-69 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CO689_RS11890 485532eeb83a4fb7dbf06a26e3b946ca 591 Gene3D G3DSA:3.40.920.10 2 181 1.8E-45 T 28-03-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 CO689_RS11890 485532eeb83a4fb7dbf06a26e3b946ca 591 SUPERFAMILY SSF53323 2 221 1.24E-44 T 28-03-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 CO689_RS11890 485532eeb83a4fb7dbf06a26e3b946ca 591 Pfam PF17147 Pyruvate:ferredoxin oxidoreductase core domain II 476 552 6.8E-10 T 28-03-2018 IPR033412 Pyruvate:ferredoxin oxidoreductase, core domain II CO689_RS11890 485532eeb83a4fb7dbf06a26e3b946ca 591 Gene3D G3DSA:3.40.50.970 195 486 1.3E-58 T 28-03-2018 CO689_RS11890 485532eeb83a4fb7dbf06a26e3b946ca 591 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 14 175 8.1E-43 T 28-03-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 CO689_RS09955 e5028156c9c3a8d710618d9f5c98481a 401 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 5 325 2.5E-40 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CO689_RS09955 e5028156c9c3a8d710618d9f5c98481a 401 SUPERFAMILY SSF51905 162 338 4.87E-18 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CO689_RS09955 e5028156c9c3a8d710618d9f5c98481a 401 Gene3D G3DSA:3.50.50.60 3 129 2.0E-12 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CO689_RS09955 e5028156c9c3a8d710618d9f5c98481a 401 Gene3D G3DSA:3.50.50.60 130 334 2.1E-24 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CO689_RS09955 e5028156c9c3a8d710618d9f5c98481a 401 SUPERFAMILY SSF51905 4 211 4.89E-28 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CO689_RS02955 d8637c8ec17a7433a6299e5e8c5cee5c 159 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 4 154 8.2E-30 T 28-03-2018 IPR002178 PTS EIIA type-2 domain CO689_RS02955 d8637c8ec17a7433a6299e5e8c5cee5c 159 Gene3D G3DSA:3.40.930.10 1 157 1.4E-29 T 28-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 CO689_RS02955 d8637c8ec17a7433a6299e5e8c5cee5c 159 SUPERFAMILY SSF55804 2 154 1.27E-28 T 28-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 CO689_RS04530 81b1c2965d5a19355656d7794b44e7db 336 Pfam PF13602 Zinc-binding dehydrogenase 189 332 3.3E-30 T 28-03-2018 CO689_RS04530 81b1c2965d5a19355656d7794b44e7db 336 SUPERFAMILY SSF50129 4 151 1.05E-35 T 28-03-2018 IPR011032 GroES-like CO689_RS04530 81b1c2965d5a19355656d7794b44e7db 336 Gene3D G3DSA:3.90.180.10 1 155 1.6E-51 T 28-03-2018 CO689_RS04530 81b1c2965d5a19355656d7794b44e7db 336 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 33 94 2.8E-12 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CO689_RS04530 81b1c2965d5a19355656d7794b44e7db 336 SUPERFAMILY SSF51735 119 300 4.78E-37 T 28-03-2018 IPR016040 NAD(P)-binding domain CO689_RS04530 81b1c2965d5a19355656d7794b44e7db 336 Gene3D G3DSA:3.90.180.10 262 335 2.3E-9 T 28-03-2018 CO689_RS04530 81b1c2965d5a19355656d7794b44e7db 336 SMART SM00829 15 332 9.1E-35 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CO689_RS04530 81b1c2965d5a19355656d7794b44e7db 336 ProSitePatterns PS01162 Quinone oxidoreductase / zeta-crystallin signature. 147 168 - T 28-03-2018 IPR002364 Quinone oxidoreductase/zeta-crystallin, conserved site GO:0008270|GO:0016491 CO689_RS04530 81b1c2965d5a19355656d7794b44e7db 336 Gene3D G3DSA:3.40.50.720 156 261 2.5E-11 T 28-03-2018 CO689_RS03090 ca644169334bac6625af81eba6a9c505 179 SUPERFAMILY SSF55282 3 178 5.89E-79 T 28-03-2018 IPR022803 Ribosomal protein L5 domain Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CO689_RS03090 ca644169334bac6625af81eba6a9c505 179 PIRSF PIRSF002161 2 179 1.7E-71 T 28-03-2018 IPR002132 Ribosomal protein L5 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CO689_RS03090 ca644169334bac6625af81eba6a9c505 179 Hamap MF_01333_B 50S ribosomal protein L5 [rplE]. 1 179 45.315 T 28-03-2018 IPR020930 Ribosomal protein L5, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 CO689_RS03090 ca644169334bac6625af81eba6a9c505 179 Gene3D G3DSA:3.30.1440.10 1 179 3.1E-81 T 28-03-2018 IPR022803 Ribosomal protein L5 domain Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CO689_RS03090 ca644169334bac6625af81eba6a9c505 179 ProSitePatterns PS00358 Ribosomal protein L5 signature. 57 73 - T 28-03-2018 IPR020929 Ribosomal protein L5, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CO689_RS03090 ca644169334bac6625af81eba6a9c505 179 Pfam PF00281 Ribosomal protein L5 24 80 2.0E-28 T 28-03-2018 IPR031310 Ribosomal protein L5, N-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CO689_RS03090 ca644169334bac6625af81eba6a9c505 179 Pfam PF00673 ribosomal L5P family C-terminus 84 177 1.3E-42 T 28-03-2018 IPR031309 Ribosomal protein L5, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CO689_RS13570 2de534f338424cb453150ec8a1f908b3 106 SUPERFAMILY SSF118010 1 106 6.41E-32 T 28-03-2018 IPR007422 Cysteine protease Prp CO689_RS13570 2de534f338424cb453150ec8a1f908b3 106 Gene3D G3DSA:3.30.70.1490 1 106 6.5E-28 T 28-03-2018 IPR007422 Cysteine protease Prp CO689_RS13570 2de534f338424cb453150ec8a1f908b3 106 Pfam PF04327 Cysteine protease Prp 1 102 5.5E-23 T 28-03-2018 IPR007422 Cysteine protease Prp CO689_RS01950 24f35c082cde3e6d4afeef38983a227b 295 Pfam PF00005 ABC transporter 16 148 1.2E-24 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CO689_RS01950 24f35c082cde3e6d4afeef38983a227b 295 SMART SM00382 25 196 1.8E-6 T 28-03-2018 IPR003593 AAA+ ATPase domain CO689_RS01950 24f35c082cde3e6d4afeef38983a227b 295 SUPERFAMILY SSF52540 2 204 4.05E-49 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CO689_RS01950 24f35c082cde3e6d4afeef38983a227b 295 Gene3D G3DSA:3.40.50.300 1 258 5.8E-47 T 28-03-2018 CO689_RS10585 37290f9006332a7459944c25eec33a60 157 Pfam PF02082 Transcriptional regulator 1 83 1.4E-20 T 28-03-2018 IPR000944 Transcription regulator Rrf2-type CO689_RS10585 37290f9006332a7459944c25eec33a60 157 Gene3D G3DSA:1.10.10.10 1 147 2.3E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS10585 37290f9006332a7459944c25eec33a60 157 ProSitePatterns PS01332 Rrf2-type HTH domain signature. 49 67 - T 28-03-2018 IPR030489 Transcription regulator Rrf2-type, conserved site CO689_RS10585 37290f9006332a7459944c25eec33a60 157 SUPERFAMILY SSF46785 2 140 1.56E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS10585 37290f9006332a7459944c25eec33a60 157 TIGRFAM TIGR00738 rrf2_super: Rrf2 family protein 1 136 2.2E-24 T 28-03-2018 IPR000944 Transcription regulator Rrf2-type CO689_RS04200 41131706ebdf8b4fb2bda5fed56a5a40 153 PIRSF PIRSF006187 1 149 1.6E-31 T 28-03-2018 IPR009736 Protein of unknown function DUF1307 CO689_RS04200 41131706ebdf8b4fb2bda5fed56a5a40 153 Gene3D G3DSA:3.30.1830.10 25 147 1.1E-27 T 28-03-2018 CO689_RS04200 41131706ebdf8b4fb2bda5fed56a5a40 153 SUPERFAMILY SSF160704 21 148 6.93E-31 T 28-03-2018 IPR009736 Protein of unknown function DUF1307 CO689_RS04200 41131706ebdf8b4fb2bda5fed56a5a40 153 Pfam PF06998 Protein of unknown function (DUF1307) 25 144 7.3E-31 T 28-03-2018 IPR009736 Protein of unknown function DUF1307 CO689_RS06365 d8b799129ee4951589ceea7e1898e738 340 SMART SM00829 8 334 1.4E-5 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CO689_RS06365 d8b799129ee4951589ceea7e1898e738 340 SUPERFAMILY SSF51735 132 300 6.65E-41 T 28-03-2018 IPR016040 NAD(P)-binding domain CO689_RS06365 d8b799129ee4951589ceea7e1898e738 340 Gene3D G3DSA:3.90.180.10 1 160 5.8E-49 T 28-03-2018 CO689_RS06365 d8b799129ee4951589ceea7e1898e738 340 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 59 73 - T 28-03-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 CO689_RS06365 d8b799129ee4951589ceea7e1898e738 340 Pfam PF00107 Zinc-binding dehydrogenase 168 296 1.4E-29 T 28-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CO689_RS06365 d8b799129ee4951589ceea7e1898e738 340 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 25 128 2.2E-24 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CO689_RS06365 d8b799129ee4951589ceea7e1898e738 340 SUPERFAMILY SSF50129 1 167 1.03E-43 T 28-03-2018 IPR011032 GroES-like CO689_RS06365 d8b799129ee4951589ceea7e1898e738 340 Gene3D G3DSA:3.40.50.720 161 280 1.3E-27 T 28-03-2018 CO689_RS02905 9e06e64f253264ff33a93df2e53797a1 336 Pfam PF00107 Zinc-binding dehydrogenase 160 259 4.6E-14 T 28-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CO689_RS02905 9e06e64f253264ff33a93df2e53797a1 336 TIGRFAM TIGR02817 adh_fam_1: zinc-binding alcohol dehydrogenase family protein 2 332 7.1E-95 T 28-03-2018 IPR014182 Alcohol dehydrogenase, zinc-binding type 1 GO:0008270 CO689_RS02905 9e06e64f253264ff33a93df2e53797a1 336 Gene3D G3DSA:3.90.180.10 1 155 1.2E-37 T 28-03-2018 CO689_RS02905 9e06e64f253264ff33a93df2e53797a1 336 SMART SM00829 15 332 3.0E-10 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CO689_RS02905 9e06e64f253264ff33a93df2e53797a1 336 SUPERFAMILY SSF51735 115 273 4.04E-30 T 28-03-2018 IPR016040 NAD(P)-binding domain CO689_RS02905 9e06e64f253264ff33a93df2e53797a1 336 SUPERFAMILY SSF50129 8 141 3.96E-29 T 28-03-2018 IPR011032 GroES-like CO689_RS02905 9e06e64f253264ff33a93df2e53797a1 336 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 31 90 2.2E-6 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CO689_RS02905 9e06e64f253264ff33a93df2e53797a1 336 ProSitePatterns PS01162 Quinone oxidoreductase / zeta-crystallin signature. 149 170 - T 28-03-2018 IPR002364 Quinone oxidoreductase/zeta-crystallin, conserved site GO:0008270|GO:0016491 CO689_RS02905 9e06e64f253264ff33a93df2e53797a1 336 Gene3D G3DSA:3.40.50.720 156 269 3.8E-17 T 28-03-2018 CO689_RS08110 366080eece966e0da25ff522f1d8a6c0 154 Pfam PF00583 Acetyltransferase (GNAT) family 20 143 2.5E-16 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CO689_RS08110 366080eece966e0da25ff522f1d8a6c0 154 Gene3D G3DSA:3.40.630.30 6 149 1.1E-24 T 28-03-2018 CO689_RS08110 366080eece966e0da25ff522f1d8a6c0 154 SUPERFAMILY SSF55729 16 147 9.21E-25 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CO689_RS03370 c2bc016367187ab3f5deeb7689cbf2bf 314 Gene3D G3DSA:3.90.245.10 1 314 8.1E-64 T 28-03-2018 IPR001910 Inosine/uridine-preferring nucleoside hydrolase domain CO689_RS03370 c2bc016367187ab3f5deeb7689cbf2bf 314 Pfam PF01156 Inosine-uridine preferring nucleoside hydrolase 3 303 2.4E-48 T 28-03-2018 IPR001910 Inosine/uridine-preferring nucleoside hydrolase domain CO689_RS03370 c2bc016367187ab3f5deeb7689cbf2bf 314 SUPERFAMILY SSF53590 1 309 5.49E-79 T 28-03-2018 IPR001910 Inosine/uridine-preferring nucleoside hydrolase domain CO689_RS11925 3113b41338191cc5be6017a99dabefc5 328 Gene3D G3DSA:3.40.50.300 3 328 3.0E-85 T 28-03-2018 CO689_RS11925 3113b41338191cc5be6017a99dabefc5 328 Pfam PF00005 ABC transporter 34 184 3.3E-31 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CO689_RS11925 3113b41338191cc5be6017a99dabefc5 328 ProSitePatterns PS00211 ABC transporters family signature. 157 171 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CO689_RS11925 3113b41338191cc5be6017a99dabefc5 328 SMART SM00382 42 234 3.3E-13 T 28-03-2018 IPR003593 AAA+ ATPase domain CO689_RS11925 3113b41338191cc5be6017a99dabefc5 328 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 236 301 9.6E-22 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CO689_RS11925 3113b41338191cc5be6017a99dabefc5 328 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 234 320 1.8E-30 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CO689_RS11925 3113b41338191cc5be6017a99dabefc5 328 SUPERFAMILY SSF52540 6 256 1.82E-72 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CO689_RS09930 a86901249a85664f3eee741d53f38595 80 SUPERFAMILY SSF117916 3 79 2.62E-25 T 28-03-2018 IPR034904 Fe-S cluster assembly domain CO689_RS09930 a86901249a85664f3eee741d53f38595 80 ProDom PD002830 NIFU NIFU NITROGEN-FIXING C-TERMINAL FIXATION NITROGEN NIFU-LIKE DOMAIN CLUSTER HESB/YADR/YFHF:NITROGEN-FIXING 17 66 4.0E-22 T 28-03-2018 IPR001075 NIF system FeS cluster assembly, NifU, C-terminal GO:0005506|GO:0016226|GO:0051536 CO689_RS09930 a86901249a85664f3eee741d53f38595 80 Gene3D G3DSA:3.30.300.130 3 80 5.6E-27 T 28-03-2018 IPR034904 Fe-S cluster assembly domain CO689_RS09930 a86901249a85664f3eee741d53f38595 80 Pfam PF01106 NifU-like domain 14 77 7.1E-26 T 28-03-2018 IPR001075 NIF system FeS cluster assembly, NifU, C-terminal GO:0005506|GO:0016226|GO:0051536 CO689_RS02270 e009626799554be092317c42e8a69cf1 333 Gene3D G3DSA:1.10.1240.30 2 80 1.0E-11 T 28-03-2018 IPR017944 KaiA/RbsU helical domain GO:0006468 CO689_RS02270 e009626799554be092317c42e8a69cf1 333 SUPERFAMILY SSF101215 2 81 1.9E-12 T 28-03-2018 IPR017944 KaiA/RbsU helical domain GO:0006468 CO689_RS02270 e009626799554be092317c42e8a69cf1 333 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 143 331 1.3E-44 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CO689_RS02270 e009626799554be092317c42e8a69cf1 333 SUPERFAMILY SSF81606 129 330 3.4E-13 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CO689_RS02270 e009626799554be092317c42e8a69cf1 333 ProDom PD685490 RSBU REGULATOR SIGMA REGULATION FACTOR B PHOSPHATASE SIGMAB INDIRECT SIGMA-B 1 90 9.0E-13 T 28-03-2018 IPR014787 Phosphoserine phosphatase RsbU, N-terminal KEGG: 00260+3.1.3.3|KEGG: 00680+3.1.3.3 CO689_RS02270 e009626799554be092317c42e8a69cf1 333 SMART SM00331 116 331 2.9E-65 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CO689_RS02270 e009626799554be092317c42e8a69cf1 333 Pfam PF08673 Phosphoserine phosphatase RsbU, N-terminal domain 6 79 5.7E-15 T 28-03-2018 IPR014787 Phosphoserine phosphatase RsbU, N-terminal KEGG: 00260+3.1.3.3|KEGG: 00680+3.1.3.3 CO689_RS02270 e009626799554be092317c42e8a69cf1 333 Gene3D G3DSA:3.60.40.10 82 332 1.3E-30 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CO689_RS02270 e009626799554be092317c42e8a69cf1 333 SMART SM00332 95 329 2.6E-5 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CO689_RS04560 443269533e19e5afc6c178a6dd06fa11 152 Pfam PF11457 Protein of unknown function (DUF3021) 5 151 8.9E-35 T 28-03-2018 IPR021560 Protein of unknown function DUF3021 CO689_RS00415 747d4eb56a37da6d01e584720abbfb6f 893 Gene3D G3DSA:1.20.1640.10 79 344 9.5E-36 T 28-03-2018 CO689_RS00415 747d4eb56a37da6d01e584720abbfb6f 893 SUPERFAMILY SSF82866 125 332 2.09E-30 T 28-03-2018 CO689_RS00415 747d4eb56a37da6d01e584720abbfb6f 893 SUPERFAMILY SSF82866 454 692 1.7E-30 T 28-03-2018 CO689_RS00415 747d4eb56a37da6d01e584720abbfb6f 893 Gene3D G3DSA:1.20.1640.10 469 690 5.6E-32 T 28-03-2018 CO689_RS00415 747d4eb56a37da6d01e584720abbfb6f 893 Pfam PF03176 MMPL family 46 359 1.7E-62 T 28-03-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 CO689_RS00415 747d4eb56a37da6d01e584720abbfb6f 893 Pfam PF03176 MMPL family 389 695 9.3E-40 T 28-03-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 CO689_RS06490 d1a4084b5f2956f945338a817cf9c14a 331 ProSitePatterns PS00356 LacI-type HTH domain signature. 6 24 - T 28-03-2018 CO689_RS06490 d1a4084b5f2956f945338a817cf9c14a 331 Pfam PF13377 Periplasmic binding protein-like domain 170 326 1.4E-34 T 28-03-2018 CO689_RS06490 d1a4084b5f2956f945338a817cf9c14a 331 Gene3D G3DSA:3.40.50.2300 56 175 6.6E-23 T 28-03-2018 CO689_RS06490 d1a4084b5f2956f945338a817cf9c14a 331 SUPERFAMILY SSF47413 1 60 3.7E-14 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CO689_RS06490 d1a4084b5f2956f945338a817cf9c14a 331 Pfam PF00356 Bacterial regulatory proteins, lacI family 5 51 7.3E-16 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CO689_RS06490 d1a4084b5f2956f945338a817cf9c14a 331 Gene3D G3DSA:1.10.260.40 4 55 3.7E-16 T 28-03-2018 CO689_RS06490 d1a4084b5f2956f945338a817cf9c14a 331 SUPERFAMILY SSF53822 63 327 2.17E-65 T 28-03-2018 IPR028082 Periplasmic binding protein-like I CO689_RS06490 d1a4084b5f2956f945338a817cf9c14a 331 Gene3D G3DSA:3.40.50.2300 176 331 1.1E-43 T 28-03-2018 CO689_RS06490 d1a4084b5f2956f945338a817cf9c14a 331 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 15 25 2.0E-5 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CO689_RS06490 d1a4084b5f2956f945338a817cf9c14a 331 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 5 15 2.0E-5 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CO689_RS06490 d1a4084b5f2956f945338a817cf9c14a 331 SMART SM00354 3 74 5.9E-26 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CO689_RS00570 38f49897d465bec66fbf5f7c7bc7ea6b 281 SUPERFAMILY SSF56601 25 281 1.01E-71 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CO689_RS00570 38f49897d465bec66fbf5f7c7bc7ea6b 281 PRINTS PR00118 Beta-lactamase class A signature 57 74 1.3E-47 T 28-03-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 CO689_RS00570 38f49897d465bec66fbf5f7c7bc7ea6b 281 PRINTS PR00118 Beta-lactamase class A signature 159 184 1.3E-47 T 28-03-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 CO689_RS00570 38f49897d465bec66fbf5f7c7bc7ea6b 281 PRINTS PR00118 Beta-lactamase class A signature 133 157 1.3E-47 T 28-03-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 CO689_RS00570 38f49897d465bec66fbf5f7c7bc7ea6b 281 PRINTS PR00118 Beta-lactamase class A signature 212 227 1.3E-47 T 28-03-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 CO689_RS00570 38f49897d465bec66fbf5f7c7bc7ea6b 281 PRINTS PR00118 Beta-lactamase class A signature 26 50 1.3E-47 T 28-03-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 CO689_RS00570 38f49897d465bec66fbf5f7c7bc7ea6b 281 PRINTS PR00118 Beta-lactamase class A signature 97 122 1.3E-47 T 28-03-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 CO689_RS00570 38f49897d465bec66fbf5f7c7bc7ea6b 281 PRINTS PR00118 Beta-lactamase class A signature 195 210 1.3E-47 T 28-03-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 CO689_RS00570 38f49897d465bec66fbf5f7c7bc7ea6b 281 Gene3D G3DSA:3.40.710.10 24 281 1.9E-38 T 28-03-2018 CO689_RS00570 38f49897d465bec66fbf5f7c7bc7ea6b 281 ProSitePatterns PS00146 Beta-lactamase class-A active site. 59 74 - T 28-03-2018 IPR023650 Beta-lactamase, class-A active site KEGG: 00311+3.5.2.6 CO689_RS00570 38f49897d465bec66fbf5f7c7bc7ea6b 281 Pfam PF13354 Beta-lactamase enzyme family 46 246 8.3E-37 T 28-03-2018 CO689_RS12715 710fda8d22ca3a48cb2656edafa39b60 430 Pfam PF01336 OB-fold nucleic acid binding domain 16 95 8.9E-15 T 28-03-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 CO689_RS12715 710fda8d22ca3a48cb2656edafa39b60 430 TIGRFAM TIGR00457 asnS: asparagine--tRNA ligase 2 429 1.1E-164 T 28-03-2018 IPR004522 Asparagine-tRNA ligase GO:0000166|GO:0004816|GO:0005524|GO:0005737|GO:0006421 KEGG: 00970+6.1.1.22 CO689_RS12715 710fda8d22ca3a48cb2656edafa39b60 430 Hamap MF_00534 Asparagine--tRNA ligase [asnS]. 1 430 42.04 T 28-03-2018 IPR004522 Asparagine-tRNA ligase GO:0000166|GO:0004816|GO:0005524|GO:0005737|GO:0006421 KEGG: 00970+6.1.1.22 CO689_RS12715 710fda8d22ca3a48cb2656edafa39b60 430 Pfam PF00152 tRNA synthetases class II (D, K and N) 111 424 9.3E-85 T 28-03-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 CO689_RS12715 710fda8d22ca3a48cb2656edafa39b60 430 Gene3D G3DSA:2.40.50.140 1 100 4.3E-21 T 28-03-2018 CO689_RS12715 710fda8d22ca3a48cb2656edafa39b60 430 PRINTS PR01042 Aspartyl-tRNA synthetase signature 385 399 7.6E-16 T 28-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 CO689_RS12715 710fda8d22ca3a48cb2656edafa39b60 430 PRINTS PR01042 Aspartyl-tRNA synthetase signature 196 209 7.6E-16 T 28-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 CO689_RS12715 710fda8d22ca3a48cb2656edafa39b60 430 PRINTS PR01042 Aspartyl-tRNA synthetase signature 345 361 7.6E-16 T 28-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 CO689_RS12715 710fda8d22ca3a48cb2656edafa39b60 430 PRINTS PR01042 Aspartyl-tRNA synthetase signature 180 192 7.6E-16 T 28-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 CO689_RS12715 710fda8d22ca3a48cb2656edafa39b60 430 SUPERFAMILY SSF55681 110 424 1.86E-98 T 28-03-2018 CO689_RS12715 710fda8d22ca3a48cb2656edafa39b60 430 Gene3D G3DSA:3.30.930.10 101 430 1.3E-94 T 28-03-2018 CO689_RS12715 710fda8d22ca3a48cb2656edafa39b60 430 SUPERFAMILY SSF50249 9 102 4.5E-24 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CO689_RS04030 602ffff1e08fa9cab91a954f63afe864 199 Gene3D G3DSA:3.40.30.10 22 199 1.6E-27 T 28-03-2018 CO689_RS04030 602ffff1e08fa9cab91a954f63afe864 199 SUPERFAMILY SSF52833 27 198 2.73E-28 T 28-03-2018 IPR012336 Thioredoxin-like fold CO689_RS04030 602ffff1e08fa9cab91a954f63afe864 199 Pfam PF13462 Thioredoxin 32 198 4.3E-24 T 28-03-2018 IPR012336 Thioredoxin-like fold CO689_RS12030 f3c5deabbf9ede253436f6764359e9cd 444 Gene3D G3DSA:3.90.350.10 142 290 2.9E-6 T 28-03-2018 IPR014736 Transposase, Tn5-like, core CO689_RS12030 f3c5deabbf9ede253436f6764359e9cd 444 Pfam PF05598 Transposase domain (DUF772) 52 127 3.1E-21 T 28-03-2018 IPR008490 Transposase InsH, N-terminal CO689_RS12030 f3c5deabbf9ede253436f6764359e9cd 444 Pfam PF13751 Transposase DDE domain 321 439 1.0E-21 T 28-03-2018 IPR025668 Transposase DDE domain CO689_RS12875 4b946c629c47aa5351b96e984aef9803 182 SUPERFAMILY SSF46785 78 150 3.4E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS12875 4b946c629c47aa5351b96e984aef9803 182 Gene3D G3DSA:1.10.10.10 3 76 5.0E-9 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS12875 4b946c629c47aa5351b96e984aef9803 182 Gene3D G3DSA:1.10.10.10 77 167 3.3E-26 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS12875 4b946c629c47aa5351b96e984aef9803 182 TIGRFAM TIGR00281 TIGR00281: segregation and condensation protein B 8 179 3.0E-38 T 28-03-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 CO689_RS12875 4b946c629c47aa5351b96e984aef9803 182 Pfam PF04079 Segregation and condensation complex subunit ScpB 8 158 1.1E-40 T 28-03-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 CO689_RS12875 4b946c629c47aa5351b96e984aef9803 182 SUPERFAMILY SSF46785 5 74 2.63E-7 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS12875 4b946c629c47aa5351b96e984aef9803 182 PIRSF PIRSF019345 1 180 5.3E-40 T 28-03-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 CO689_RS03110 31a6c1c28a48bae78c4948ccf4b92546 69 Pfam PF00831 Ribosomal L29 protein 4 60 2.8E-24 T 28-03-2018 IPR001854 Ribosomal protein L29/L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CO689_RS03110 31a6c1c28a48bae78c4948ccf4b92546 69 Gene3D G3DSA:1.10.287.310 1 65 1.5E-24 T 28-03-2018 CO689_RS03110 31a6c1c28a48bae78c4948ccf4b92546 69 SUPERFAMILY SSF46561 1 63 7.72E-23 T 28-03-2018 IPR001854 Ribosomal protein L29/L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CO689_RS03110 31a6c1c28a48bae78c4948ccf4b92546 69 TIGRFAM TIGR00012 L29: ribosomal protein uL29 5 60 2.6E-22 T 28-03-2018 IPR001854 Ribosomal protein L29/L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CO689_RS03110 31a6c1c28a48bae78c4948ccf4b92546 69 Hamap MF_00374 50S ribosomal protein L29 [rpmC]. 1 60 18.564 T 28-03-2018 IPR001854 Ribosomal protein L29/L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CO689_RS03125 6ba728e0a7ac969bfc02fba1765675c9 117 Gene3D G3DSA:3.90.470.10 1 117 2.9E-43 T 28-03-2018 CO689_RS03125 6ba728e0a7ac969bfc02fba1765675c9 117 SUPERFAMILY SSF54843 1 111 3.14E-43 T 28-03-2018 IPR001063 Ribosomal protein L22/L17 GO:0003735|GO:0005840|GO:0006412 CO689_RS03125 6ba728e0a7ac969bfc02fba1765675c9 117 Hamap MF_01331_B 50S ribosomal protein L22 [rplV]. 1 110 29.523 T 28-03-2018 IPR005727 Ribosomal protein L22, bacterial/chloroplast-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CO689_RS03125 6ba728e0a7ac969bfc02fba1765675c9 117 ProSitePatterns PS00464 Ribosomal protein L22 signature. 83 107 - T 28-03-2018 IPR018260 Ribosomal protein L22/L17, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CO689_RS03125 6ba728e0a7ac969bfc02fba1765675c9 117 TIGRFAM TIGR01044 rplV_bact: ribosomal protein uL22 5 107 8.9E-47 T 28-03-2018 IPR005727 Ribosomal protein L22, bacterial/chloroplast-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CO689_RS03125 6ba728e0a7ac969bfc02fba1765675c9 117 Pfam PF00237 Ribosomal protein L22p/L17e 5 107 5.8E-36 T 28-03-2018 IPR001063 Ribosomal protein L22/L17 GO:0003735|GO:0005840|GO:0006412 CO689_RS00275 3867783f15d6aad4a94eb57dedc9438e 224 Gene3D G3DSA:3.30.420.10 70 217 1.2E-16 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CO689_RS00275 3867783f15d6aad4a94eb57dedc9438e 224 SUPERFAMILY SSF53098 70 216 5.06E-10 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CO689_RS00275 3867783f15d6aad4a94eb57dedc9438e 224 Gene3D G3DSA:1.10.10.10 5 69 4.2E-5 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS00275 3867783f15d6aad4a94eb57dedc9438e 224 Pfam PF13610 DDE domain 72 203 1.1E-38 T 28-03-2018 IPR032874 DDE domain CO689_RS07765 c6c538c1922658ecddf3493e4df6cd84 426 Pfam PF01171 PP-loop family 14 195 9.3E-58 T 28-03-2018 IPR011063 tRNA(Ile)-lysidine/2-thiocytidine synthase, N-terminal Reactome: R-HSA-6782315 CO689_RS07765 c6c538c1922658ecddf3493e4df6cd84 426 Pfam PF11734 TilS substrate C-terminal domain 356 417 3.4E-10 T 28-03-2018 IPR012796 Lysidine-tRNA(Ile) synthetase, C-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 CO689_RS07765 c6c538c1922658ecddf3493e4df6cd84 426 TIGRFAM TIGR02433 lysidine_TilS_C: tRNA(Ile)-lysidine synthetase, C-terminal domain 355 399 4.3E-15 T 28-03-2018 IPR012796 Lysidine-tRNA(Ile) synthetase, C-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 CO689_RS07765 c6c538c1922658ecddf3493e4df6cd84 426 SUPERFAMILY SSF52402 8 202 2.65E-50 T 28-03-2018 CO689_RS07765 c6c538c1922658ecddf3493e4df6cd84 426 SUPERFAMILY SSF56037 325 415 1.12E-13 T 28-03-2018 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 CO689_RS07765 c6c538c1922658ecddf3493e4df6cd84 426 Gene3D G3DSA:3.40.50.620 5 200 8.7E-41 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CO689_RS07765 c6c538c1922658ecddf3493e4df6cd84 426 Hamap MF_01161 tRNA(Ile)-lysidine synthase [tilS]. 1 307 21.647 T 28-03-2018 IPR012094 tRNA(Ile)-lysidine synthase GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 CO689_RS07765 c6c538c1922658ecddf3493e4df6cd84 426 TIGRFAM TIGR02432 lysidine_TilS_N: tRNA(Ile)-lysidine synthetase 14 199 6.7E-57 T 28-03-2018 IPR012795 tRNA(Ile)-lysidine synthase, N-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 CO689_RS07765 c6c538c1922658ecddf3493e4df6cd84 426 SMART SM00977 354 424 2.1E-15 T 28-03-2018 IPR012796 Lysidine-tRNA(Ile) synthetase, C-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 CO689_RS12100 3042b606832c032cafbad99d81990083 304 TIGRFAM TIGR00191 thrB: homoserine kinase 5 301 2.8E-78 T 28-03-2018 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 CO689_RS12100 3042b606832c032cafbad99d81990083 304 Hamap MF_00384 Homoserine kinase [thrB]. 5 299 30.329 T 28-03-2018 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 CO689_RS12100 3042b606832c032cafbad99d81990083 304 Gene3D G3DSA:3.30.70.890 162 290 4.8E-22 T 28-03-2018 IPR013750 GHMP kinase, C-terminal domain CO689_RS12100 3042b606832c032cafbad99d81990083 304 ProSitePatterns PS00627 GHMP kinases putative ATP-binding domain. 89 100 - T 28-03-2018 IPR006203 GHMP kinase, ATP-binding, conserved site GO:0005524 CO689_RS12100 3042b606832c032cafbad99d81990083 304 Gene3D G3DSA:3.30.230.10 4 156 6.6E-28 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CO689_RS12100 3042b606832c032cafbad99d81990083 304 Pfam PF08544 GHMP kinases C terminal 205 283 2.2E-9 T 28-03-2018 IPR013750 GHMP kinase, C-terminal domain CO689_RS12100 3042b606832c032cafbad99d81990083 304 SUPERFAMILY SSF54211 5 150 2.5E-30 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CO689_RS12100 3042b606832c032cafbad99d81990083 304 Pfam PF00288 GHMP kinases N terminal domain 82 143 7.8E-12 T 28-03-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 CO689_RS12100 3042b606832c032cafbad99d81990083 304 PIRSF PIRSF000676 1 302 6.6E-85 T 28-03-2018 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 CO689_RS12100 3042b606832c032cafbad99d81990083 304 SUPERFAMILY SSF55060 167 284 1.98E-30 T 28-03-2018 IPR013750 GHMP kinase, C-terminal domain CO689_RS12100 3042b606832c032cafbad99d81990083 304 PRINTS PR00958 Homoserine kinase signature 170 187 6.1E-37 T 28-03-2018 CO689_RS12100 3042b606832c032cafbad99d81990083 304 PRINTS PR00958 Homoserine kinase signature 12 27 6.1E-37 T 28-03-2018 CO689_RS12100 3042b606832c032cafbad99d81990083 304 PRINTS PR00958 Homoserine kinase signature 96 111 6.1E-37 T 28-03-2018 CO689_RS12100 3042b606832c032cafbad99d81990083 304 PRINTS PR00958 Homoserine kinase signature 250 265 6.1E-37 T 28-03-2018 CO689_RS12100 3042b606832c032cafbad99d81990083 304 PRINTS PR00958 Homoserine kinase signature 130 143 6.1E-37 T 28-03-2018 CO689_RS12930 be8135ce457e6170256a7697a72f6c8f 284 Pfam PF14526 Integron-associated effector binding protein 133 280 6.6E-15 T 28-03-2018 IPR029441 Integron-associated effector binding protein CO689_RS12930 be8135ce457e6170256a7697a72f6c8f 284 Pfam PF12833 Helix-turn-helix domain 27 102 8.5E-12 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CO689_RS12930 be8135ce457e6170256a7697a72f6c8f 284 SUPERFAMILY SSF46689 5 53 2.11E-7 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CO689_RS12930 be8135ce457e6170256a7697a72f6c8f 284 SMART SM00342 21 104 2.6E-13 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CO689_RS12930 be8135ce457e6170256a7697a72f6c8f 284 Gene3D G3DSA:3.20.80.10 130 282 7.2E-11 T 28-03-2018 IPR011256 Regulatory factor, effector binding domain CO689_RS12930 be8135ce457e6170256a7697a72f6c8f 284 Gene3D G3DSA:3.90.1240.10 1 129 2.8E-18 T 28-03-2018 CO689_RS12930 be8135ce457e6170256a7697a72f6c8f 284 SUPERFAMILY SSF46689 58 104 8.96E-5 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CO689_RS12930 be8135ce457e6170256a7697a72f6c8f 284 SMART SM00871 128 281 0.0019 T 28-03-2018 IPR010499 Bacterial transcription activator, effector binding CO689_RS12930 be8135ce457e6170256a7697a72f6c8f 284 SUPERFAMILY SSF55136 169 280 4.71E-9 T 28-03-2018 CO689_RS13860 b5055e26b36857bac766599e51644cc3 1066 Pfam PF07733 Bacterial DNA polymerase III alpha subunit 252 670 1.5E-165 T 28-03-2018 IPR011708 Bacterial DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CO689_RS13860 b5055e26b36857bac766599e51644cc3 1066 Gene3D G3DSA:1.10.150.280 728 828 3.8E-7 T 28-03-2018 CO689_RS13860 b5055e26b36857bac766599e51644cc3 1066 SUPERFAMILY SSF89550 1 88 5.49E-8 T 28-03-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 CO689_RS13860 b5055e26b36857bac766599e51644cc3 1066 Gene3D G3DSA:2.40.50.140 893 990 7.9E-8 T 28-03-2018 CO689_RS13860 b5055e26b36857bac766599e51644cc3 1066 TIGRFAM TIGR00594 polc: DNA polymerase III, alpha subunit 150 949 5.3E-264 T 28-03-2018 IPR004805 DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CO689_RS13860 b5055e26b36857bac766599e51644cc3 1066 SMART SM00481 3 70 2.6E-16 T 28-03-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal CO689_RS13860 b5055e26b36857bac766599e51644cc3 1066 Pfam PF14579 Helix-hairpin-helix motif 744 831 2.2E-23 T 28-03-2018 IPR029460 DNA polymerase, helix-hairpin-helix motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CO689_RS13860 b5055e26b36857bac766599e51644cc3 1066 Gene3D G3DSA:3.20.20.140 1 500 4.0E-25 T 28-03-2018 CO689_RS13860 b5055e26b36857bac766599e51644cc3 1066 Pfam PF02811 PHP domain 4 124 3.7E-23 T 28-03-2018 IPR004013 PHP domain GO:0003824 CO689_RS07150 c24752a5fa8b7800292187ed8a59e5e0 172 TIGRFAM TIGR00621 ssb: single-stranded DNA-binding protein 1 172 3.9E-47 T 28-03-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 CO689_RS07150 c24752a5fa8b7800292187ed8a59e5e0 172 SUPERFAMILY SSF50249 1 172 1.1E-55 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CO689_RS07150 c24752a5fa8b7800292187ed8a59e5e0 172 Gene3D G3DSA:2.40.50.140 1 122 6.2E-39 T 28-03-2018 CO689_RS07150 c24752a5fa8b7800292187ed8a59e5e0 172 Hamap MF_00984 Single-stranded DNA-binding protein. 2 107 35.395 T 28-03-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 CO689_RS07150 c24752a5fa8b7800292187ed8a59e5e0 172 Pfam PF00436 Single-strand binding protein family 2 103 1.4E-35 T 28-03-2018 IPR000424 Primosome PriB/single-strand DNA-binding GO:0003697 Reactome: R-HSA-2151201 CO689_RS07150 c24752a5fa8b7800292187ed8a59e5e0 172 PIRSF PIRSF002070 1 155 2.2E-39 T 28-03-2018 CO689_RS05285 a2a0488e27ac709eb1c1ef64c19358cb 190 Pfam PF04343 Protein of unknown function, DUF488 20 143 4.8E-27 T 28-03-2018 IPR007438 Protein of unknown function DUF488 CO689_RS05285 a2a0488e27ac709eb1c1ef64c19358cb 190 PIRSF PIRSF024492 5 188 9.4E-51 T 28-03-2018 IPR014519 Uncharacterised conserved protein UCP024492 CO689_RS05285 a2a0488e27ac709eb1c1ef64c19358cb 190 Gene3D G3DSA:3.90.190.10 1 158 1.8E-4 T 28-03-2018 IPR029021 Protein-tyrosine phosphatase-like CO689_RS12220 63daf2f790c156d2d1bbe789725a007b 901 PRINTS PR00415 Aconitase family signature 202 215 1.0E-41 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CO689_RS12220 63daf2f790c156d2d1bbe789725a007b 901 PRINTS PR00415 Aconitase family signature 145 158 1.0E-41 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CO689_RS12220 63daf2f790c156d2d1bbe789725a007b 901 PRINTS PR00415 Aconitase family signature 278 291 1.0E-41 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CO689_RS12220 63daf2f790c156d2d1bbe789725a007b 901 PRINTS PR00415 Aconitase family signature 372 386 1.0E-41 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CO689_RS12220 63daf2f790c156d2d1bbe789725a007b 901 PRINTS PR00415 Aconitase family signature 292 305 1.0E-41 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CO689_RS12220 63daf2f790c156d2d1bbe789725a007b 901 PRINTS PR00415 Aconitase family signature 438 449 1.0E-41 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CO689_RS12220 63daf2f790c156d2d1bbe789725a007b 901 PRINTS PR00415 Aconitase family signature 500 513 1.0E-41 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CO689_RS12220 63daf2f790c156d2d1bbe789725a007b 901 PRINTS PR00415 Aconitase family signature 169 177 1.0E-41 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CO689_RS12220 63daf2f790c156d2d1bbe789725a007b 901 PRINTS PR00415 Aconitase family signature 216 231 1.0E-41 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CO689_RS12220 63daf2f790c156d2d1bbe789725a007b 901 SUPERFAMILY SSF53732 10 634 2.75E-221 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CO689_RS12220 63daf2f790c156d2d1bbe789725a007b 901 ProSitePatterns PS01244 Aconitase family signature 2. 500 513 - T 28-03-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 CO689_RS12220 63daf2f790c156d2d1bbe789725a007b 901 SUPERFAMILY SSF52016 638 897 1.26E-84 T 28-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel CO689_RS12220 63daf2f790c156d2d1bbe789725a007b 901 Gene3D G3DSA:3.30.499.10 372 583 3.2E-65 T 28-03-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 CO689_RS12220 63daf2f790c156d2d1bbe789725a007b 901 Gene3D G3DSA:3.40.1060.10 239 371 1.9E-46 T 28-03-2018 IPR015932 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 2 GO:0008152 KEGG: 00290+4.2.1.33 CO689_RS12220 63daf2f790c156d2d1bbe789725a007b 901 ProSitePatterns PS00450 Aconitase family signature 1. 434 450 - T 28-03-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 CO689_RS12220 63daf2f790c156d2d1bbe789725a007b 901 Gene3D G3DSA:3.20.19.10 661 899 1.4E-91 T 28-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel CO689_RS12220 63daf2f790c156d2d1bbe789725a007b 901 Pfam PF00694 Aconitase C-terminal domain 699 826 2.0E-43 T 28-03-2018 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain GO:0008152 KEGG: 00290+4.2.1.33 CO689_RS12220 63daf2f790c156d2d1bbe789725a007b 901 Pfam PF00330 Aconitase family (aconitate hydratase) 75 569 5.7E-178 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CO689_RS12220 63daf2f790c156d2d1bbe789725a007b 901 TIGRFAM TIGR01341 aconitase_1: aconitate hydratase 1 19 898 0.0 T 28-03-2018 IPR006249 Aconitase/Iron-responsive element-binding protein 2 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00720+4.2.1.3|Reactome: R-HSA-917937 CO689_RS12220 63daf2f790c156d2d1bbe789725a007b 901 Gene3D G3DSA:3.30.499.10 26 238 1.2E-67 T 28-03-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 CO689_RS11050 484d0663d7605415ae1b06c3149dbda4 352 Pfam PF01409 tRNA synthetases class II core domain (F) 95 343 1.5E-107 T 28-03-2018 IPR002319 Phenylalanyl-tRNA synthetase GO:0000049|GO:0004812|GO:0005524|GO:0005737|GO:0043039 KEGG: 00970+6.1.1.20 CO689_RS11050 484d0663d7605415ae1b06c3149dbda4 352 TIGRFAM TIGR00468 pheS: phenylalanine--tRNA ligase, alpha subunit 42 344 2.4E-114 T 28-03-2018 IPR004529 Phenylalanyl-tRNA synthetase, class IIc, alpha subunit GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 CO689_RS11050 484d0663d7605415ae1b06c3149dbda4 352 Gene3D G3DSA:3.30.930.10 10 347 9.4E-95 T 28-03-2018 CO689_RS11050 484d0663d7605415ae1b06c3149dbda4 352 SUPERFAMILY SSF55681 95 344 5.39E-81 T 28-03-2018 CO689_RS11050 484d0663d7605415ae1b06c3149dbda4 352 Pfam PF02912 Aminoacyl tRNA synthetase class II, N-terminal domain 23 90 7.6E-27 T 28-03-2018 IPR004188 Phenylalanine-tRNA ligase, class II, N-terminal GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 CO689_RS11050 484d0663d7605415ae1b06c3149dbda4 352 Hamap MF_00281 Phenylalanine--tRNA ligase alpha subunit [pheS]. 11 343 48.194 T 28-03-2018 IPR022911 Phenylalanine-tRNA ligase alpha chain 1, bacterial GO:0004826 KEGG: 00970+6.1.1.20 CO689_RS11050 484d0663d7605415ae1b06c3149dbda4 352 SUPERFAMILY SSF46589 15 102 4.24E-23 T 28-03-2018 IPR010978 tRNA-binding arm GO:0000166 CO689_RS10780 9df4be9b9789d41a3cd8150e596dcb1a 469 Gene3D G3DSA:3.40.50.300 1 242 9.2E-49 T 28-03-2018 CO689_RS10780 9df4be9b9789d41a3cd8150e596dcb1a 469 SUPERFAMILY SSF52540 253 456 7.7E-43 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CO689_RS10780 9df4be9b9789d41a3cd8150e596dcb1a 469 SMART SM00382 28 222 6.1E-10 T 28-03-2018 IPR003593 AAA+ ATPase domain CO689_RS10780 9df4be9b9789d41a3cd8150e596dcb1a 469 SMART SM00382 277 455 5.6E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain CO689_RS10780 9df4be9b9789d41a3cd8150e596dcb1a 469 ProSitePatterns PS00211 ABC transporters family signature. 130 144 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CO689_RS10780 9df4be9b9789d41a3cd8150e596dcb1a 469 SUPERFAMILY SSF52540 2 223 3.38E-45 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CO689_RS10780 9df4be9b9789d41a3cd8150e596dcb1a 469 Gene3D G3DSA:3.40.50.300 245 459 7.8E-43 T 28-03-2018 CO689_RS10780 9df4be9b9789d41a3cd8150e596dcb1a 469 Pfam PF00005 ABC transporter 272 405 2.9E-23 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CO689_RS10780 9df4be9b9789d41a3cd8150e596dcb1a 469 Pfam PF00005 ABC transporter 20 158 1.2E-21 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CO689_RS07425 9d57e8065299e7a99c352859455c2008 259 SUPERFAMILY SSF54001 4 251 2.75E-59 T 28-03-2018 CO689_RS07425 9d57e8065299e7a99c352859455c2008 259 Pfam PF00797 N-acetyltransferase 22 250 1.3E-57 T 28-03-2018 IPR001447 Arylamine N-acetyltransferase GO:0008152|GO:0016407 KEGG: 00232+2.3.1.5|KEGG: 00633+2.3.1.5|KEGG: 00983+2.3.1.5|Reactome: R-HSA-156582 CO689_RS07425 9d57e8065299e7a99c352859455c2008 259 Gene3D G3DSA:3.30.2140.10 3 163 5.4E-28 T 28-03-2018 CO689_RS07425 9d57e8065299e7a99c352859455c2008 259 Gene3D G3DSA:3.30.2140.10 164 254 3.0E-11 T 28-03-2018 CO689_RS07425 9d57e8065299e7a99c352859455c2008 259 PRINTS PR01543 Arylamine N-acetyltransferase signature 101 126 1.7E-11 T 28-03-2018 IPR001447 Arylamine N-acetyltransferase GO:0008152|GO:0016407 KEGG: 00232+2.3.1.5|KEGG: 00633+2.3.1.5|KEGG: 00983+2.3.1.5|Reactome: R-HSA-156582 CO689_RS07425 9d57e8065299e7a99c352859455c2008 259 PRINTS PR01543 Arylamine N-acetyltransferase signature 46 69 1.7E-11 T 28-03-2018 IPR001447 Arylamine N-acetyltransferase GO:0008152|GO:0016407 KEGG: 00232+2.3.1.5|KEGG: 00633+2.3.1.5|KEGG: 00983+2.3.1.5|Reactome: R-HSA-156582 CO689_RS07425 9d57e8065299e7a99c352859455c2008 259 PRINTS PR01543 Arylamine N-acetyltransferase signature 22 45 1.7E-11 T 28-03-2018 IPR001447 Arylamine N-acetyltransferase GO:0008152|GO:0016407 KEGG: 00232+2.3.1.5|KEGG: 00633+2.3.1.5|KEGG: 00983+2.3.1.5|Reactome: R-HSA-156582 CO689_RS08940 b2dd98f3974c027fa9f8e18c511b3f44 592 SUPERFAMILY SSF47819 514 589 1.02E-17 T 28-03-2018 IPR010997 HRDC-like GO:0000166|GO:0003824|GO:0044237 CO689_RS08940 b2dd98f3974c027fa9f8e18c511b3f44 592 Pfam PF00570 HRDC domain 519 585 9.2E-17 T 28-03-2018 IPR002121 HRDC domain GO:0003676|GO:0005622 CO689_RS08940 b2dd98f3974c027fa9f8e18c511b3f44 592 SUPERFAMILY SSF46785 393 500 2.58E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS08940 b2dd98f3974c027fa9f8e18c511b3f44 592 Pfam PF16124 RecQ zinc-binding 332 395 3.3E-12 T 28-03-2018 IPR032284 ATP-dependent DNA helicase RecQ, zinc-binding domain CO689_RS08940 b2dd98f3974c027fa9f8e18c511b3f44 592 SMART SM00956 402 502 2.1E-26 T 28-03-2018 IPR018982 RQC domain GO:0006260|GO:0006281|GO:0043140 Reactome: R-HSA-3108214|Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473 CO689_RS08940 b2dd98f3974c027fa9f8e18c511b3f44 592 TIGRFAM TIGR00614 recQ_fam: ATP-dependent DNA helicase, RecQ family 5 453 2.7E-138 T 28-03-2018 IPR004589 DNA helicase, ATP-dependent, RecQ type GO:0006310|GO:0008026 CO689_RS08940 b2dd98f3974c027fa9f8e18c511b3f44 592 SUPERFAMILY SSF52540 53 340 3.85E-60 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CO689_RS08940 b2dd98f3974c027fa9f8e18c511b3f44 592 Gene3D G3DSA:3.40.50.300 1 197 2.3E-31 T 28-03-2018 CO689_RS08940 b2dd98f3974c027fa9f8e18c511b3f44 592 Pfam PF00271 Helicase conserved C-terminal domain 220 319 1.9E-21 T 28-03-2018 IPR001650 Helicase, C-terminal CO689_RS08940 b2dd98f3974c027fa9f8e18c511b3f44 592 SMART SM00487 10 207 1.3E-28 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CO689_RS08940 b2dd98f3974c027fa9f8e18c511b3f44 592 Gene3D G3DSA:1.10.10.10 395 506 1.8E-25 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS08940 b2dd98f3974c027fa9f8e18c511b3f44 592 Gene3D G3DSA:1.10.150.80 507 592 7.3E-20 T 28-03-2018 CO689_RS08940 b2dd98f3974c027fa9f8e18c511b3f44 592 SMART SM00490 239 320 1.2E-27 T 28-03-2018 IPR001650 Helicase, C-terminal CO689_RS08940 b2dd98f3974c027fa9f8e18c511b3f44 592 Pfam PF00270 DEAD/DEAH box helicase 16 178 2.1E-19 T 28-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CO689_RS08940 b2dd98f3974c027fa9f8e18c511b3f44 592 Gene3D G3DSA:3.40.50.300 199 394 1.1E-49 T 28-03-2018 CO689_RS08940 b2dd98f3974c027fa9f8e18c511b3f44 592 TIGRFAM TIGR01389 recQ: ATP-dependent DNA helicase RecQ 2 588 7.8E-253 T 28-03-2018 IPR006293 DNA helicase, ATP-dependent, RecQ type, bacterial GO:0004003|GO:0006310|GO:0009432 CO689_RS08940 b2dd98f3974c027fa9f8e18c511b3f44 592 Pfam PF09382 RQC domain 399 503 8.1E-25 T 28-03-2018 IPR018982 RQC domain GO:0006260|GO:0006281|GO:0043140 Reactome: R-HSA-3108214|Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473 CO689_RS08940 b2dd98f3974c027fa9f8e18c511b3f44 592 SMART SM00341 515 588 4.9E-9 T 28-03-2018 IPR002121 HRDC domain GO:0003676|GO:0005622 CO689_RS09015 0bc287d56e6e13886e26e6b1fe9b24cb 342 Pfam PF01497 Periplasmic binding protein 74 318 1.9E-33 T 28-03-2018 IPR002491 ABC transporter periplasmic binding domain GO:0005488 CO689_RS09015 0bc287d56e6e13886e26e6b1fe9b24cb 342 SUPERFAMILY SSF53807 61 333 2.2E-60 T 28-03-2018 CO689_RS09015 0bc287d56e6e13886e26e6b1fe9b24cb 342 Gene3D G3DSA:3.40.50.1980 25 179 8.0E-27 T 28-03-2018 CO689_RS09015 0bc287d56e6e13886e26e6b1fe9b24cb 342 Gene3D G3DSA:3.40.50.1980 180 342 4.8E-34 T 28-03-2018 CO689_RS11430 bac69ad29678ab18aa23f3e0a093a390 186 Pfam PF13692 Glycosyl transferases group 1 7 153 3.4E-14 T 28-03-2018 CO689_RS11430 bac69ad29678ab18aa23f3e0a093a390 186 SUPERFAMILY SSF53756 4 186 2.46E-20 T 28-03-2018 CO689_RS11430 bac69ad29678ab18aa23f3e0a093a390 186 Gene3D G3DSA:3.40.50.2000 1 172 8.6E-19 T 28-03-2018 CO689_RS01835 fafb710cd8f20a50defbe085d17992a8 432 Gene3D G3DSA:1.10.40.30 349 428 1.7E-25 T 28-03-2018 CO689_RS01835 fafb710cd8f20a50defbe085d17992a8 432 Pfam PF10397 Adenylosuccinate lyase C-terminus 350 428 8.7E-25 T 28-03-2018 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CO689_RS01835 fafb710cd8f20a50defbe085d17992a8 432 PRINTS PR00149 Fumarate lyase superfamily signature 261 277 1.5E-25 T 28-03-2018 IPR000362 Fumarate lyase family CO689_RS01835 fafb710cd8f20a50defbe085d17992a8 432 PRINTS PR00149 Fumarate lyase superfamily signature 216 243 1.5E-25 T 28-03-2018 IPR000362 Fumarate lyase family CO689_RS01835 fafb710cd8f20a50defbe085d17992a8 432 PRINTS PR00149 Fumarate lyase superfamily signature 88 106 1.5E-25 T 28-03-2018 IPR000362 Fumarate lyase family CO689_RS01835 fafb710cd8f20a50defbe085d17992a8 432 PRINTS PR00149 Fumarate lyase superfamily signature 133 151 1.5E-25 T 28-03-2018 IPR000362 Fumarate lyase family CO689_RS01835 fafb710cd8f20a50defbe085d17992a8 432 TIGRFAM TIGR00928 purB: adenylosuccinate lyase 1 427 1.5E-170 T 28-03-2018 IPR004769 Adenylosuccinate lyase GO:0004018|GO:0009152 KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CO689_RS01835 fafb710cd8f20a50defbe085d17992a8 432 PRINTS PR00145 Argininosuccinate lyase family signature 128 148 1.8E-8 T 28-03-2018 CO689_RS01835 fafb710cd8f20a50defbe085d17992a8 432 PRINTS PR00145 Argininosuccinate lyase family signature 261 277 1.8E-8 T 28-03-2018 CO689_RS01835 fafb710cd8f20a50defbe085d17992a8 432 PRINTS PR00145 Argininosuccinate lyase family signature 87 109 1.8E-8 T 28-03-2018 CO689_RS01835 fafb710cd8f20a50defbe085d17992a8 432 PRINTS PR00145 Argininosuccinate lyase family signature 216 240 1.8E-8 T 28-03-2018 CO689_RS01835 fafb710cd8f20a50defbe085d17992a8 432 ProSitePatterns PS00163 Fumarate lyases signature. 261 270 - T 28-03-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 CO689_RS01835 fafb710cd8f20a50defbe085d17992a8 432 Pfam PF00206 Lyase 7 286 1.3E-71 T 28-03-2018 IPR022761 Fumarate lyase, N-terminal CO689_RS01835 fafb710cd8f20a50defbe085d17992a8 432 SUPERFAMILY SSF48557 3 428 4.87E-139 T 28-03-2018 IPR008948 L-Aspartase-like GO:0003824 CO689_RS01835 fafb710cd8f20a50defbe085d17992a8 432 Gene3D G3DSA:1.10.275.10 2 92 2.7E-24 T 28-03-2018 IPR024083 Fumarase/histidase, N-terminal CO689_RS01835 fafb710cd8f20a50defbe085d17992a8 432 Gene3D G3DSA:1.20.200.10 93 348 6.9E-81 T 28-03-2018 CO689_RS01835 fafb710cd8f20a50defbe085d17992a8 432 SMART SM00998 349 429 3.7E-38 T 28-03-2018 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CO689_RS03485 4958d5b1e01548c27daa9f8ae1341a24 110 SUPERFAMILY SSF103481 6 101 8.76E-15 T 28-03-2018 CO689_RS03485 4958d5b1e01548c27daa9f8ae1341a24 110 Pfam PF00893 Small Multidrug Resistance protein 1 90 1.7E-20 T 28-03-2018 IPR000390 Small multidrug resistance protein family GO:0016021 CO689_RS01840 75c559b8ea32b668324b72e36d133861 57 Pfam PF14044 NETI protein 2 54 3.4E-26 T 28-03-2018 IPR025930 NETI protein CO689_RS05340 8976c13232eb9e60496a50f538be9d54 369 Gene3D G3DSA:3.30.470.20 170 348 3.9E-8 T 28-03-2018 CO689_RS05340 8976c13232eb9e60496a50f538be9d54 369 Pfam PF13535 ATP-grasp domain 132 271 4.7E-13 T 28-03-2018 CO689_RS05340 8976c13232eb9e60496a50f538be9d54 369 Gene3D G3DSA:3.30.1490.20 121 169 4.7E-12 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CO689_RS05340 8976c13232eb9e60496a50f538be9d54 369 SUPERFAMILY SSF56059 130 336 7.07E-23 T 28-03-2018 CO689_RS05340 8976c13232eb9e60496a50f538be9d54 369 SUPERFAMILY SSF52440 2 68 2.68E-6 T 28-03-2018 IPR016185 Pre-ATP-grasp domain CO689_RS05340 8976c13232eb9e60496a50f538be9d54 369 Gene3D G3DSA:3.40.50.20 1 115 5.1E-16 T 28-03-2018 CO689_RS01180 5f49dbb13139497077071ea611aa6966 278 ProSitePatterns PS00798 Aldo/keto reductase family signature 1. 39 56 - T 28-03-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 CO689_RS01180 5f49dbb13139497077071ea611aa6966 278 Gene3D G3DSA:3.20.20.100 1 276 2.4E-94 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CO689_RS01180 5f49dbb13139497077071ea611aa6966 278 ProSitePatterns PS00062 Aldo/keto reductase family signature 2. 127 144 - T 28-03-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 CO689_RS01180 5f49dbb13139497077071ea611aa6966 278 SUPERFAMILY SSF51430 3 268 1.83E-89 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CO689_RS01180 5f49dbb13139497077071ea611aa6966 278 PIRSF PIRSF000097 1 277 2.8E-94 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CO689_RS01180 5f49dbb13139497077071ea611aa6966 278 ProSitePatterns PS00063 Aldo/keto reductase family putative active site signature. 231 246 - T 28-03-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 CO689_RS01180 5f49dbb13139497077071ea611aa6966 278 PRINTS PR00069 Aldo-keto reductase signature 198 222 2.2E-46 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CO689_RS01180 5f49dbb13139497077071ea611aa6966 278 PRINTS PR00069 Aldo-keto reductase signature 95 113 2.2E-46 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CO689_RS01180 5f49dbb13139497077071ea611aa6966 278 PRINTS PR00069 Aldo-keto reductase signature 161 190 2.2E-46 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CO689_RS01180 5f49dbb13139497077071ea611aa6966 278 PRINTS PR00069 Aldo-keto reductase signature 35 59 2.2E-46 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CO689_RS01180 5f49dbb13139497077071ea611aa6966 278 PRINTS PR00069 Aldo-keto reductase signature 127 144 2.2E-46 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CO689_RS01180 5f49dbb13139497077071ea611aa6966 278 Pfam PF00248 Aldo/keto reductase family 15 262 7.7E-47 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CO689_RS06280 866778231fe8837906ed03390f707daa 282 Gene3D G3DSA:2.40.30.90 166 281 2.7E-25 T 28-03-2018 IPR023227 S-adenosyl-l-methionine hydroxide adenosyltransferase, C-terminal CO689_RS06280 866778231fe8837906ed03390f707daa 282 PIRSF PIRSF006779 1 277 1.0E-98 T 28-03-2018 IPR002747 SAM-dependent chlorinase/fluorinase CO689_RS06280 866778231fe8837906ed03390f707daa 282 Gene3D G3DSA:3.40.50.10790 3 165 9.2E-54 T 28-03-2018 CO689_RS06280 866778231fe8837906ed03390f707daa 282 SUPERFAMILY SSF101852 171 275 4.32E-29 T 28-03-2018 IPR023227 S-adenosyl-l-methionine hydroxide adenosyltransferase, C-terminal CO689_RS06280 866778231fe8837906ed03390f707daa 282 Pfam PF01887 S-adenosyl-l-methionine hydroxide adenosyltransferase 6 272 3.2E-70 T 28-03-2018 IPR002747 SAM-dependent chlorinase/fluorinase CO689_RS06280 866778231fe8837906ed03390f707daa 282 SUPERFAMILY SSF102522 4 166 1.96E-55 T 28-03-2018 IPR023228 S-adenosyl-l-methionine hydroxide adenosyltransferase, N-terminal CO689_RS08920 23a30eb0e3680d0706ecaf1f4cad2f0e 235 Gene3D G3DSA:3.30.1360.40 1 87 9.1E-7 T 28-03-2018 IPR024946 Arginine repressor C-terminal-like domain Reactome: R-HSA-4615885 CO689_RS08920 23a30eb0e3680d0706ecaf1f4cad2f0e 235 SMART SM00796 1 209 2.8E-65 T 28-03-2018 IPR003833 Carboxyltransferase domain, subdomain C and D CO689_RS08920 23a30eb0e3680d0706ecaf1f4cad2f0e 235 Gene3D G3DSA:2.40.100.10 94 227 3.6E-36 T 28-03-2018 IPR029000 Cyclophilin-like domain CO689_RS08920 23a30eb0e3680d0706ecaf1f4cad2f0e 235 SUPERFAMILY SSF50891 95 222 2.24E-36 T 28-03-2018 IPR029000 Cyclophilin-like domain CO689_RS08920 23a30eb0e3680d0706ecaf1f4cad2f0e 235 TIGRFAM TIGR00370 TIGR00370: sensor histidine kinase inhibitor, KipI family 7 217 3.6E-44 T 28-03-2018 IPR010016 KipI family CO689_RS08920 23a30eb0e3680d0706ecaf1f4cad2f0e 235 SUPERFAMILY SSF160467 2 95 1.83E-11 T 28-03-2018 CO689_RS08920 23a30eb0e3680d0706ecaf1f4cad2f0e 235 Pfam PF02682 Carboxyltransferase domain, subdomain C and D 1 209 1.5E-42 T 28-03-2018 IPR003833 Carboxyltransferase domain, subdomain C and D CO689_RS08815 81b5774f6f8d9918dd1d10c16f2544bb 162 SUPERFAMILY SSF55826 6 156 7.46E-40 T 28-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 CO689_RS08815 81b5774f6f8d9918dd1d10c16f2544bb 162 Gene3D G3DSA:3.90.960.10 1 159 6.4E-40 T 28-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 CO689_RS08815 81b5774f6f8d9918dd1d10c16f2544bb 162 Pfam PF04073 Aminoacyl-tRNA editing domain 34 146 1.0E-20 T 28-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 CO689_RS08815 81b5774f6f8d9918dd1d10c16f2544bb 162 TIGRFAM TIGR00011 YbaK_EbsC: Cys-tRNA(Pro) deacylase 6 156 2.6E-55 T 28-03-2018 IPR004369 Prolyl-tRNA editing protein, YbaK/EbsC CO689_RS08815 81b5774f6f8d9918dd1d10c16f2544bb 162 PIRSF PIRSF006181 1 160 6.6E-59 T 28-03-2018 IPR004369 Prolyl-tRNA editing protein, YbaK/EbsC CO689_RS08975 2f13d53922e880b431536a1f802dc16d 167 PIRSF PIRSF027377 9 149 4.9E-63 T 28-03-2018 IPR016856 NADPH-dependent 7-cyano-7-deazaguanine reductase, QueF type 1 GO:0005737|GO:0008616|GO:0046857|GO:0055114 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 CO689_RS08975 2f13d53922e880b431536a1f802dc16d 167 Pfam PF14489 QueF-like protein 64 142 6.7E-35 T 28-03-2018 IPR029500 NADPH-dependent 7-cyano-7-deazaguanine reductase QueF GO:0008616|GO:0033739 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 CO689_RS08975 2f13d53922e880b431536a1f802dc16d 167 TIGRFAM TIGR03139 QueF-II: 7-cyano-7-deazaguanine reductase 30 140 2.4E-53 T 28-03-2018 IPR016856 NADPH-dependent 7-cyano-7-deazaguanine reductase, QueF type 1 GO:0005737|GO:0008616|GO:0046857|GO:0055114 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 CO689_RS08975 2f13d53922e880b431536a1f802dc16d 167 Hamap MF_00818 NADPH-dependent 7-cyano-7-deazaguanine reductase [queF]. 1 167 71.573 T 28-03-2018 IPR016856 NADPH-dependent 7-cyano-7-deazaguanine reductase, QueF type 1 GO:0005737|GO:0008616|GO:0046857|GO:0055114 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 CO689_RS08975 2f13d53922e880b431536a1f802dc16d 167 SUPERFAMILY SSF55620 30 138 8.15E-28 T 28-03-2018 CO689_RS08975 2f13d53922e880b431536a1f802dc16d 167 Gene3D G3DSA:3.30.1130.10 23 167 3.7E-42 T 28-03-2018 CO689_RS07990 47fd3a973459c1596c823b5eace89474 247 SUPERFAMILY SSF75217 67 243 8.5E-51 T 28-03-2018 IPR029028 Alpha/beta knot methyltransferases CO689_RS07990 47fd3a973459c1596c823b5eace89474 247 SMART SM00967 5 79 6.9E-19 T 28-03-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 CO689_RS07990 47fd3a973459c1596c823b5eace89474 247 TIGRFAM TIGR00186 rRNA_methyl_3: RNA methyltransferase, TrmH family, group 3 4 242 5.2E-82 T 28-03-2018 IPR004441 RNA methyltransferase TrmH family GO:0006396|GO:0008173 Reactome: R-HSA-6793080 CO689_RS07990 47fd3a973459c1596c823b5eace89474 247 Pfam PF08032 RNA 2'-O ribose methyltransferase substrate binding 6 78 9.1E-20 T 28-03-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 CO689_RS07990 47fd3a973459c1596c823b5eace89474 247 SUPERFAMILY SSF55315 5 76 2.24E-15 T 28-03-2018 IPR029064 50S ribosomal protein L30e-like CO689_RS07990 47fd3a973459c1596c823b5eace89474 247 Gene3D G3DSA:3.40.1280.10 78 246 3.5E-49 T 28-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal CO689_RS07990 47fd3a973459c1596c823b5eace89474 247 Pfam PF00588 SpoU rRNA Methylase family 98 236 8.2E-41 T 28-03-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 CO689_RS07990 47fd3a973459c1596c823b5eace89474 247 Gene3D G3DSA:3.30.1330.30 2 75 2.8E-15 T 28-03-2018 IPR029064 50S ribosomal protein L30e-like CO689_RS01685 8469bc54b0d14bf0f303a8a22d5ae0ef 383 Pfam PF04055 Radical SAM superfamily 39 189 1.1E-10 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CO689_RS01685 8469bc54b0d14bf0f303a8a22d5ae0ef 383 Gene3D G3DSA:3.20.20.70 27 371 9.3E-27 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CO689_RS01685 8469bc54b0d14bf0f303a8a22d5ae0ef 383 Pfam PF13353 4Fe-4S single cluster domain 44 137 3.7E-6 T 28-03-2018 CO689_RS01685 8469bc54b0d14bf0f303a8a22d5ae0ef 383 Pfam PF08756 YfkB-like domain 223 373 2.0E-74 T 28-03-2018 IPR014866 YfkB-like domain CO689_RS01685 8469bc54b0d14bf0f303a8a22d5ae0ef 383 TIGRFAM TIGR04478 rSAM_YfkAB: radical SAM/CxCxxxxC motif protein YfkAB 11 373 4.4E-186 T 28-03-2018 IPR031004 Radical SAM/CxCxxxxC motif protein YfkAB CO689_RS01685 8469bc54b0d14bf0f303a8a22d5ae0ef 383 SUPERFAMILY SSF102114 34 263 1.83E-25 T 28-03-2018 CO689_RS07040 a06637a12841dfe41197de49fe912335 459 Gene3D G3DSA:3.30.1360.120 2 125 2.0E-41 T 28-03-2018 CO689_RS07040 a06637a12841dfe41197de49fe912335 459 Hamap MF_00379 tRNA modification GTPase MnmE [mnmE]. 4 459 33.717 T 28-03-2018 IPR004520 tRNA modification GTPase MnmE GO:0003924|GO:0005525|GO:0005622|GO:0006400 Reactome: R-HSA-6787450 CO689_RS07040 a06637a12841dfe41197de49fe912335 459 SUPERFAMILY SSF116878 125 225 4.45E-48 T 28-03-2018 CO689_RS07040 a06637a12841dfe41197de49fe912335 459 SUPERFAMILY SSF116878 384 459 4.45E-48 T 28-03-2018 CO689_RS07040 a06637a12841dfe41197de49fe912335 459 Gene3D G3DSA:1.20.120.430 287 459 1.6E-33 T 28-03-2018 CO689_RS07040 a06637a12841dfe41197de49fe912335 459 PRINTS PR00449 Transforming protein P21 ras signature 262 284 4.9E-5 T 28-03-2018 CO689_RS07040 a06637a12841dfe41197de49fe912335 459 PRINTS PR00449 Transforming protein P21 ras signature 326 339 4.9E-5 T 28-03-2018 CO689_RS07040 a06637a12841dfe41197de49fe912335 459 PRINTS PR00449 Transforming protein P21 ras signature 222 243 4.9E-5 T 28-03-2018 CO689_RS07040 a06637a12841dfe41197de49fe912335 459 Pfam PF10396 GTP-binding protein TrmE N-terminus 5 124 8.9E-38 T 28-03-2018 IPR018948 GTP-binding protein TrmE, N-terminal Reactome: R-HSA-6787450 CO689_RS07040 a06637a12841dfe41197de49fe912335 459 Pfam PF01926 50S ribosome-binding GTPase 225 336 2.6E-24 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CO689_RS07040 a06637a12841dfe41197de49fe912335 459 SUPERFAMILY SSF52540 202 375 2.71E-41 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CO689_RS07040 a06637a12841dfe41197de49fe912335 459 SUPERFAMILY SSF52540 78 167 2.71E-41 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CO689_RS07040 a06637a12841dfe41197de49fe912335 459 TIGRFAM TIGR00450 mnmE_trmE_thdF: tRNA modification GTPase TrmE 11 459 1.4E-126 T 28-03-2018 IPR004520 tRNA modification GTPase MnmE GO:0003924|GO:0005525|GO:0005622|GO:0006400 Reactome: R-HSA-6787450 CO689_RS07040 a06637a12841dfe41197de49fe912335 459 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 225 373 1.5E-26 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 CO689_RS07040 a06637a12841dfe41197de49fe912335 459 Gene3D G3DSA:1.20.120.430 126 286 1.5E-26 T 28-03-2018 CO689_RS07040 a06637a12841dfe41197de49fe912335 459 Pfam PF12631 MnmE helical domain 127 456 2.8E-58 T 28-03-2018 IPR025867 MnmE, helical domain Reactome: R-HSA-6787450 CO689_RS00510 b5dca9ef7589fe36fd91596b952a8d49 62 Gene3D G3DSA:1.10.1470.10 2 62 4.7E-15 T 28-03-2018 IPR008462 CsbD-like domain CO689_RS00510 b5dca9ef7589fe36fd91596b952a8d49 62 Pfam PF05532 CsbD-like 3 52 4.0E-16 T 28-03-2018 IPR008462 CsbD-like domain CO689_RS00510 b5dca9ef7589fe36fd91596b952a8d49 62 SUPERFAMILY SSF69047 5 58 4.05E-11 T 28-03-2018 IPR008462 CsbD-like domain CO689_RS09995 dcf8da241ca4b707f622efd9a45de791 498 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 164 188 7.1E-13 T 28-03-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CO689_RS09995 dcf8da241ca4b707f622efd9a45de791 498 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 238 262 7.1E-13 T 28-03-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CO689_RS09995 dcf8da241ca4b707f622efd9a45de791 498 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 378 404 7.1E-13 T 28-03-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CO689_RS09995 dcf8da241ca4b707f622efd9a45de791 498 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 134 153 7.1E-13 T 28-03-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CO689_RS09995 dcf8da241ca4b707f622efd9a45de791 498 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 326 345 7.1E-13 T 28-03-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CO689_RS09995 dcf8da241ca4b707f622efd9a45de791 498 Pfam PF00361 Proton-conducting membrane transporter 129 416 1.5E-48 T 28-03-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CO689_RS06240 e03aaec25e73b9ce04bf76fe60029347 306 Pfam PF02424 ApbE family 9 286 1.5E-77 T 28-03-2018 IPR024932 Flavin transferase ApbE GO:0017013 CO689_RS06240 e03aaec25e73b9ce04bf76fe60029347 306 Gene3D G3DSA:3.10.520.10 1 305 2.7E-54 T 28-03-2018 CO689_RS06240 e03aaec25e73b9ce04bf76fe60029347 306 SUPERFAMILY SSF143631 6 301 8.63E-91 T 28-03-2018 IPR003374 ApbE-like domain CO689_RS06240 e03aaec25e73b9ce04bf76fe60029347 306 PIRSF PIRSF006268 1 305 8.0E-99 T 28-03-2018 IPR024932 Flavin transferase ApbE GO:0017013 CO689_RS09745 05f1bbd78885d07ab4b98d59677b1f42 191 Pfam PF04586 Caudovirus prohead serine protease 12 173 2.1E-54 T 28-03-2018 IPR006433 Prohead protease CO689_RS09745 05f1bbd78885d07ab4b98d59677b1f42 191 Gene3D G3DSA:3.20.16.10 17 183 1.5E-29 T 28-03-2018 IPR035443 Herpesvirus/Caudovirus protease domain CO689_RS09745 05f1bbd78885d07ab4b98d59677b1f42 191 TIGRFAM TIGR01543 proheadase_HK97: phage prohead protease, HK97 family 22 167 4.9E-28 T 28-03-2018 IPR006433 Prohead protease CO689_RS03615 92b56994e630052a9df01ff50afb1c7a 293 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 58 289 1.3E-51 T 28-03-2018 CO689_RS03615 92b56994e630052a9df01ff50afb1c7a 293 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 198 217 1.4E-26 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CO689_RS03615 92b56994e630052a9df01ff50afb1c7a 293 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 219 236 1.4E-26 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CO689_RS03615 92b56994e630052a9df01ff50afb1c7a 293 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 254 274 1.4E-26 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CO689_RS03615 92b56994e630052a9df01ff50afb1c7a 293 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 50 67 1.4E-26 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CO689_RS03615 92b56994e630052a9df01ff50afb1c7a 293 SUPERFAMILY SSF51735 48 290 9.09E-69 T 28-03-2018 IPR016040 NAD(P)-binding domain CO689_RS03615 92b56994e630052a9df01ff50afb1c7a 293 Gene3D G3DSA:3.40.50.720 2 293 6.4E-64 T 28-03-2018 CO689_RS03615 92b56994e630052a9df01ff50afb1c7a 293 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 185 213 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CO689_RS09805 dd60ca57456972f29ee4e3ba3ff87b21 1646 Gene3D G3DSA:1.10.10.10 1554 1646 3.9E-4 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS09805 dd60ca57456972f29ee4e3ba3ff87b21 1646 TIGRFAM TIGR01665 put_anti_recept: phage minor structural protein, N-terminal region 25 335 1.0E-59 T 28-03-2018 IPR007119 Phage minor structural protein, N-terminal domain CO689_RS09805 dd60ca57456972f29ee4e3ba3ff87b21 1646 Gene3D G3DSA:2.60.120.260 960 1120 4.0E-5 T 28-03-2018 IPR008979 Galactose-binding domain-like CO689_RS09805 dd60ca57456972f29ee4e3ba3ff87b21 1646 Gene3D G3DSA:2.60.120.260 641 785 3.3E-4 T 28-03-2018 IPR008979 Galactose-binding domain-like CO689_RS02910 c3cf28356dd9b3f5a6485501bcde375f 339 Pfam PF00107 Zinc-binding dehydrogenase 158 292 2.1E-19 T 28-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CO689_RS02910 c3cf28356dd9b3f5a6485501bcde375f 339 Pfam PF16884 N-terminal domain of oxidoreductase 6 112 4.7E-32 T 28-03-2018 CO689_RS02910 c3cf28356dd9b3f5a6485501bcde375f 339 SMART SM00829 18 331 4.6E-6 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CO689_RS02910 c3cf28356dd9b3f5a6485501bcde375f 339 SUPERFAMILY SSF50129 1 143 2.69E-38 T 28-03-2018 IPR011032 GroES-like CO689_RS02910 c3cf28356dd9b3f5a6485501bcde375f 339 Gene3D G3DSA:3.90.180.10 1 148 1.2E-36 T 28-03-2018 CO689_RS02910 c3cf28356dd9b3f5a6485501bcde375f 339 SUPERFAMILY SSF51735 123 299 1.11E-46 T 28-03-2018 IPR016040 NAD(P)-binding domain CO689_RS02910 c3cf28356dd9b3f5a6485501bcde375f 339 Gene3D G3DSA:3.40.50.720 149 274 9.0E-29 T 28-03-2018 CO689_RS01725 ff32ebbc59d7c298f6b4c2b65443ff97 209 Pfam PF00072 Response regulator receiver domain 5 117 7.7E-27 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CO689_RS01725 ff32ebbc59d7c298f6b4c2b65443ff97 209 Gene3D G3DSA:3.40.50.2300 2 127 1.5E-33 T 28-03-2018 CO689_RS01725 ff32ebbc59d7c298f6b4c2b65443ff97 209 Pfam PF00196 Bacterial regulatory proteins, luxR family 147 202 4.6E-20 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CO689_RS01725 ff32ebbc59d7c298f6b4c2b65443ff97 209 SUPERFAMILY SSF52172 2 128 3.42E-33 T 28-03-2018 IPR011006 CheY-like superfamily CO689_RS01725 ff32ebbc59d7c298f6b4c2b65443ff97 209 SMART SM00448 3 116 2.2E-29 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CO689_RS01725 ff32ebbc59d7c298f6b4c2b65443ff97 209 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 178 190 6.5E-14 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CO689_RS01725 ff32ebbc59d7c298f6b4c2b65443ff97 209 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 162 178 6.5E-14 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CO689_RS01725 ff32ebbc59d7c298f6b4c2b65443ff97 209 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 148 162 6.5E-14 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CO689_RS01725 ff32ebbc59d7c298f6b4c2b65443ff97 209 Gene3D G3DSA:1.10.10.10 128 209 1.3E-26 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS01725 ff32ebbc59d7c298f6b4c2b65443ff97 209 SUPERFAMILY SSF46894 133 208 1.09E-23 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CO689_RS01725 ff32ebbc59d7c298f6b4c2b65443ff97 209 SMART SM00421 145 202 2.4E-25 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CO689_RS13005 42c48bcee7ed4cd2fbcd6a52ab009931 77 Pfam PF02609 Exonuclease VII small subunit 7 57 4.0E-20 T 28-03-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 CO689_RS13005 42c48bcee7ed4cd2fbcd6a52ab009931 77 SUPERFAMILY SSF116842 3 67 1.44E-20 T 28-03-2018 CO689_RS13005 42c48bcee7ed4cd2fbcd6a52ab009931 77 Hamap MF_00337 Exodeoxyribonuclease 7 small subunit [xseB]. 6 66 15.561 T 28-03-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 CO689_RS13005 42c48bcee7ed4cd2fbcd6a52ab009931 77 TIGRFAM TIGR01280 xseB: exodeoxyribonuclease VII, small subunit 6 61 6.4E-23 T 28-03-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 CO689_RS13005 42c48bcee7ed4cd2fbcd6a52ab009931 77 PIRSF PIRSF006488 1 77 5.3E-21 T 28-03-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 CO689_RS13005 42c48bcee7ed4cd2fbcd6a52ab009931 77 ProDom PD028235 EXONUCLEASE SMALL SUBUNIT VII EXODEOXYRIBONUCLEASE HYDROLASE NUCLEASE PROBABLE VII SIMILAR 3 48 2.0E-15 T 28-03-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 CO689_RS13005 42c48bcee7ed4cd2fbcd6a52ab009931 77 Gene3D G3DSA:1.10.287.1040 4 70 1.9E-22 T 28-03-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 CO689_RS01215 8047c785570603dc2f646295e969ad19 336 Pfam PF13378 Enolase C-terminal domain-like 143 320 8.5E-12 T 28-03-2018 IPR029065 Enolase C-terminal domain-like CO689_RS01215 8047c785570603dc2f646295e969ad19 336 Gene3D G3DSA:3.30.390.10 3 128 6.3E-13 T 28-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CO689_RS01215 8047c785570603dc2f646295e969ad19 336 TIGRFAM TIGR01928 menC_lowGC/arch: o-succinylbenzoate synthase 9 312 8.1E-82 T 28-03-2018 IPR010197 o-Succinylbenzoate synthase, MenC type 2 GO:0009234|GO:0016829 KEGG: 00010+4.2.1.11|KEGG: 00130+4.2.1.113|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-5837|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CO689_RS01215 8047c785570603dc2f646295e969ad19 336 SUPERFAMILY SSF54826 1 112 1.19E-15 T 28-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CO689_RS01215 8047c785570603dc2f646295e969ad19 336 SUPERFAMILY SSF51604 137 321 2.1E-26 T 28-03-2018 IPR029065 Enolase C-terminal domain-like CO689_RS01215 8047c785570603dc2f646295e969ad19 336 Gene3D G3DSA:3.20.20.120 129 322 1.5E-24 T 28-03-2018 IPR029065 Enolase C-terminal domain-like CO689_RS12425 c68d3e7b001316266c358c13be631758 308 TIGRFAM TIGR02138 phosphate_pstC: phosphate ABC transporter, permease protein PstC 24 304 1.2E-80 T 28-03-2018 IPR011864 Phosphate ABC transporter, permease protein PstC GO:0005315|GO:0006817|GO:0016021 CO689_RS12425 c68d3e7b001316266c358c13be631758 308 SUPERFAMILY SSF161098 27 300 1.87E-37 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CO689_RS12425 c68d3e7b001316266c358c13be631758 308 Gene3D G3DSA:1.10.3720.10 11 299 1.5E-42 T 28-03-2018 CO689_RS12425 c68d3e7b001316266c358c13be631758 308 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 100 305 1.1E-21 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CO689_RS11090 2d92a5a47af8f681219dd8d2af89d5ff 598 SUPERFAMILY SSF82771 19 100 1.31E-21 T 28-03-2018 IPR000305 GIY-YIG nuclease superfamily CO689_RS11090 2d92a5a47af8f681219dd8d2af89d5ff 598 TIGRFAM TIGR00194 uvrC: excinuclease ABC subunit C 9 573 2.8E-200 T 28-03-2018 IPR004791 UvrABC system, subunit C GO:0005737|GO:0006281|GO:0009380|GO:0009381 CO689_RS11090 2d92a5a47af8f681219dd8d2af89d5ff 598 SUPERFAMILY SSF47781 505 595 4.45E-20 T 28-03-2018 IPR010994 RuvA domain 2-like CO689_RS11090 2d92a5a47af8f681219dd8d2af89d5ff 598 Pfam PF02151 UvrB/uvrC motif 200 233 4.2E-7 T 28-03-2018 IPR001943 UVR domain GO:0005515 CO689_RS11090 2d92a5a47af8f681219dd8d2af89d5ff 598 Pfam PF01541 GIY-YIG catalytic domain 19 93 8.2E-11 T 28-03-2018 IPR000305 GIY-YIG nuclease superfamily CO689_RS11090 2d92a5a47af8f681219dd8d2af89d5ff 598 Gene3D G3DSA:1.10.150.20 525 598 4.2E-12 T 28-03-2018 CO689_RS11090 2d92a5a47af8f681219dd8d2af89d5ff 598 SUPERFAMILY SSF46600 185 238 6.8E-12 T 28-03-2018 IPR001943 UVR domain GO:0005515 CO689_RS11090 2d92a5a47af8f681219dd8d2af89d5ff 598 Gene3D G3DSA:3.40.1440.10 4 101 9.4E-26 T 28-03-2018 IPR000305 GIY-YIG nuclease superfamily CO689_RS11090 2d92a5a47af8f681219dd8d2af89d5ff 598 Hamap MF_00203 UvrABC system protein C [uvrC]. 5 590 28.871 T 28-03-2018 IPR004791 UvrABC system, subunit C GO:0005737|GO:0006281|GO:0009380|GO:0009381 CO689_RS11090 2d92a5a47af8f681219dd8d2af89d5ff 598 Gene3D G3DSA:4.10.860.10 177 237 7.4E-14 T 28-03-2018 IPR001943 UVR domain GO:0005515 CO689_RS11090 2d92a5a47af8f681219dd8d2af89d5ff 598 Pfam PF08459 UvrC Helix-hairpin-helix N-terminal 376 526 4.7E-53 T 28-03-2018 IPR001162 UvrC family homology region CO689_RS11090 2d92a5a47af8f681219dd8d2af89d5ff 598 Pfam PF14520 Helix-hairpin-helix domain 542 592 1.3E-8 T 28-03-2018 CO689_RS11090 2d92a5a47af8f681219dd8d2af89d5ff 598 SMART SM00465 18 98 5.8E-25 T 28-03-2018 IPR000305 GIY-YIG nuclease superfamily CO689_RS13740 fe739de7da2dbb838324d43f920d5ff7 313 Gene3D G3DSA:1.25.40.10 8 224 1.3E-5 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CO689_RS07210 2acc7c78b06a90994c59e48424a8b3a9 251 SUPERFAMILY SSF55469 6 250 1.44E-64 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CO689_RS07210 2acc7c78b06a90994c59e48424a8b3a9 251 Pfam PF00881 Nitroreductase family 10 164 2.9E-20 T 28-03-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 CO689_RS07210 2acc7c78b06a90994c59e48424a8b3a9 251 Gene3D G3DSA:3.40.109.10 1 251 2.4E-54 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CO689_RS07210 2acc7c78b06a90994c59e48424a8b3a9 251 PIRSF PIRSF005426 1 251 1.6E-85 T 28-03-2018 IPR016446 Flavin oxidoreductase Frp family GO:0016491|GO:0055114 CO689_RS05205 20c26a6170da14992bfe57725e9431c4 294 SUPERFAMILY SSF53697 5 247 1.71E-69 T 28-03-2018 CO689_RS05205 20c26a6170da14992bfe57725e9431c4 294 Pfam PF13580 SIS domain 35 164 2.6E-9 T 28-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 CO689_RS05205 20c26a6170da14992bfe57725e9431c4 294 Gene3D G3DSA:3.40.50.10490 10 240 3.2E-51 T 28-03-2018 CO689_RS05205 20c26a6170da14992bfe57725e9431c4 294 TIGRFAM TIGR00274 TIGR00274: N-acetylmuramic acid 6-phosphate etherase 6 293 6.8E-115 T 28-03-2018 IPR005488 N-acetylmuramic acid 6-phosphate etherase MurQ GO:0016835|GO:0046348 KEGG: 00030+4.2.1.12|KEGG: 00520+4.2.1.126 CO689_RS05205 20c26a6170da14992bfe57725e9431c4 294 Gene3D G3DSA:1.10.8.10 241 270 1.4E-4 T 28-03-2018 CO689_RS05205 20c26a6170da14992bfe57725e9431c4 294 Gene3D G3DSA:1.10.8.10 272 294 0.0019 T 28-03-2018 CO689_RS05205 20c26a6170da14992bfe57725e9431c4 294 ProSitePatterns PS01272 Glucokinase regulatory protein family signature. 185 202 - T 28-03-2018 IPR005486 Glucokinase regulatory protein, conserved site KEGG: 00030+4.2.1.12|KEGG: 00520+4.2.1.126|Reactome: R-HSA-170822|Reactome: R-HSA-5619107 CO689_RS05205 20c26a6170da14992bfe57725e9431c4 294 Hamap MF_00068 N-acetylmuramic acid 6-phosphate etherase [murQ]. 2 294 40.993 T 28-03-2018 IPR005488 N-acetylmuramic acid 6-phosphate etherase MurQ GO:0016835|GO:0046348 KEGG: 00030+4.2.1.12|KEGG: 00520+4.2.1.126 CO689_RS03880 8b20da3ba08d3eb89f4e513eca5cf8a9 425 PRINTS PR00173 Glutamate-aspartate symporter signature 336 355 8.9E-42 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CO689_RS03880 8b20da3ba08d3eb89f4e513eca5cf8a9 425 PRINTS PR00173 Glutamate-aspartate symporter signature 8 28 8.9E-42 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CO689_RS03880 8b20da3ba08d3eb89f4e513eca5cf8a9 425 PRINTS PR00173 Glutamate-aspartate symporter signature 154 176 8.9E-42 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CO689_RS03880 8b20da3ba08d3eb89f4e513eca5cf8a9 425 PRINTS PR00173 Glutamate-aspartate symporter signature 363 383 8.9E-42 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CO689_RS03880 8b20da3ba08d3eb89f4e513eca5cf8a9 425 PRINTS PR00173 Glutamate-aspartate symporter signature 201 220 8.9E-42 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CO689_RS03880 8b20da3ba08d3eb89f4e513eca5cf8a9 425 PRINTS PR00173 Glutamate-aspartate symporter signature 226 245 8.9E-42 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CO689_RS03880 8b20da3ba08d3eb89f4e513eca5cf8a9 425 PRINTS PR00173 Glutamate-aspartate symporter signature 78 103 8.9E-42 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CO689_RS03880 8b20da3ba08d3eb89f4e513eca5cf8a9 425 PRINTS PR00173 Glutamate-aspartate symporter signature 301 327 8.9E-42 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CO689_RS03880 8b20da3ba08d3eb89f4e513eca5cf8a9 425 ProSitePatterns PS00713 Sodium:dicarboxylate symporter family signature 1. 40 55 - T 28-03-2018 IPR018107 Sodium:dicarboxylate symporter, conserved site CO689_RS03880 8b20da3ba08d3eb89f4e513eca5cf8a9 425 SUPERFAMILY SSF118215 10 410 3.27E-122 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CO689_RS03880 8b20da3ba08d3eb89f4e513eca5cf8a9 425 Pfam PF00375 Sodium:dicarboxylate symporter family 11 409 3.8E-121 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CO689_RS03880 8b20da3ba08d3eb89f4e513eca5cf8a9 425 Gene3D G3DSA:1.10.3860.10 1 416 2.8E-128 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CO689_RS03880 8b20da3ba08d3eb89f4e513eca5cf8a9 425 ProSitePatterns PS00714 Sodium:dicarboxylate symporter family signature 2. 304 327 - T 28-03-2018 IPR018107 Sodium:dicarboxylate symporter, conserved site CO689_RS07620 6f7af48c1969c72089d91c3c21b8d1c1 723 Gene3D G3DSA:1.20.120.20 344 719 9.4E-4 T 28-03-2018 CO689_RS13700 8335f7f660e01cb64c138929aa82725c 327 SUPERFAMILY SSF51569 3 324 4.4E-140 T 28-03-2018 CO689_RS13700 8335f7f660e01cb64c138929aa82725c 327 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 266 281 2.3E-59 T 28-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 CO689_RS13700 8335f7f660e01cb64c138929aa82725c 327 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 296 315 2.3E-59 T 28-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 CO689_RS13700 8335f7f660e01cb64c138929aa82725c 327 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 119 133 2.3E-59 T 28-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 CO689_RS13700 8335f7f660e01cb64c138929aa82725c 327 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 241 257 2.3E-59 T 28-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 CO689_RS13700 8335f7f660e01cb64c138929aa82725c 327 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 151 170 2.3E-59 T 28-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 CO689_RS13700 8335f7f660e01cb64c138929aa82725c 327 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 189 208 2.3E-59 T 28-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 CO689_RS13700 8335f7f660e01cb64c138929aa82725c 327 PIRSF PIRSF001415 1 325 5.9E-151 T 28-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 CO689_RS13700 8335f7f660e01cb64c138929aa82725c 327 Pfam PF00490 Delta-aminolevulinic acid dehydratase 4 320 1.0E-147 T 28-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 CO689_RS13700 8335f7f660e01cb64c138929aa82725c 327 SMART SM01004 1 322 9.9E-228 T 28-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 CO689_RS13700 8335f7f660e01cb64c138929aa82725c 327 Gene3D G3DSA:3.20.20.70 1 326 4.5E-151 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CO689_RS13700 8335f7f660e01cb64c138929aa82725c 327 ProSitePatterns PS00169 Delta-aminolevulinic acid dehydratase active site. 241 253 - T 28-03-2018 IPR030656 Delta-aminolevulinic acid dehydratase, active site KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 CO689_RS05080 999e2592f0f86d11c7862c58e4e770c9 299 SUPERFAMILY SSF52540 4 219 9.75E-57 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CO689_RS05080 999e2592f0f86d11c7862c58e4e770c9 299 Pfam PF13732 Domain of unknown function (DUF4162) 212 290 5.2E-8 T 28-03-2018 IPR025302 Domain of unknown function DUF4162 CO689_RS05080 999e2592f0f86d11c7862c58e4e770c9 299 ProSitePatterns PS00211 ABC transporters family signature. 131 145 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CO689_RS05080 999e2592f0f86d11c7862c58e4e770c9 299 SMART SM00382 29 224 3.2E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain CO689_RS05080 999e2592f0f86d11c7862c58e4e770c9 299 Pfam PF00005 ABC transporter 20 159 1.5E-25 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CO689_RS05080 999e2592f0f86d11c7862c58e4e770c9 299 Gene3D G3DSA:3.40.50.300 1 284 2.7E-59 T 28-03-2018 CO689_RS13885 0ba8265a18e4193d4cba86c3c43187bc 351 SUPERFAMILY SSF53092 3 127 3.49E-19 T 28-03-2018 IPR028980 Creatinase/Aminopeptidase P, N-terminal CO689_RS13885 0ba8265a18e4193d4cba86c3c43187bc 351 Gene3D G3DSA:3.90.230.10 115 351 1.9E-75 T 28-03-2018 CO689_RS13885 0ba8265a18e4193d4cba86c3c43187bc 351 Gene3D G3DSA:3.40.350.10 2 114 4.4E-13 T 28-03-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal CO689_RS13885 0ba8265a18e4193d4cba86c3c43187bc 351 ProSitePatterns PS00491 Aminopeptidase P and proline dipeptidase signature. 286 298 - T 28-03-2018 IPR001131 Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site CO689_RS13885 0ba8265a18e4193d4cba86c3c43187bc 351 SUPERFAMILY SSF55920 129 350 1.07E-73 T 28-03-2018 IPR000994 Peptidase M24 CO689_RS13885 0ba8265a18e4193d4cba86c3c43187bc 351 Pfam PF00557 Metallopeptidase family M24 137 340 5.9E-62 T 28-03-2018 IPR000994 Peptidase M24 CO689_RS13885 0ba8265a18e4193d4cba86c3c43187bc 351 Pfam PF01321 Creatinase/Prolidase N-terminal domain 4 129 5.6E-18 T 28-03-2018 IPR000587 Creatinase, N-terminal GO:0016787 CO689_RS03405 9a9d7f9204dabe0a6a8c72514163dc04 150 Gene3D G3DSA:3.30.70.790 77 149 1.8E-22 T 28-03-2018 CO689_RS03405 9a9d7f9204dabe0a6a8c72514163dc04 150 SMART SM00988 6 71 5.1E-15 T 28-03-2018 IPR004029 UreE urease accessory, N-terminal CO689_RS03405 9a9d7f9204dabe0a6a8c72514163dc04 150 Gene3D G3DSA:2.60.260.20 1 75 5.1E-26 T 28-03-2018 CO689_RS03405 9a9d7f9204dabe0a6a8c72514163dc04 150 SUPERFAMILY SSF69287 1 75 5.62E-19 T 28-03-2018 IPR004029 UreE urease accessory, N-terminal CO689_RS03405 9a9d7f9204dabe0a6a8c72514163dc04 150 PIRSF PIRSF036402 1 150 1.6E-48 T 28-03-2018 IPR012406 Urease accessory protein UreE GO:0005737|GO:0006457|GO:0016151|GO:0018307 CO689_RS03405 9a9d7f9204dabe0a6a8c72514163dc04 150 SUPERFAMILY SSF69737 78 143 6.28E-18 T 28-03-2018 IPR007864 Urease accessory protein UreE, C-terminal domain GO:0006461|GO:0016151|GO:0019627 CO689_RS03405 9a9d7f9204dabe0a6a8c72514163dc04 150 Pfam PF05194 UreE urease accessory protein, C-terminal domain 78 137 1.2E-9 T 28-03-2018 IPR007864 Urease accessory protein UreE, C-terminal domain GO:0006461|GO:0016151|GO:0019627 CO689_RS03405 9a9d7f9204dabe0a6a8c72514163dc04 150 Pfam PF02814 UreE urease accessory protein, N-terminal domain 15 69 4.4E-17 T 28-03-2018 IPR004029 UreE urease accessory, N-terminal CO689_RS03405 9a9d7f9204dabe0a6a8c72514163dc04 150 Hamap MF_00822 Urease accessory protein UreE [ureE]. 1 149 23.523 T 28-03-2018 IPR012406 Urease accessory protein UreE GO:0005737|GO:0006457|GO:0016151|GO:0018307 CO689_RS09925 3a526d41d9af9b19d5da9c9e67ca52ad 251 Pfam PF13411 MerR HTH family regulatory protein 3 71 9.7E-15 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CO689_RS09925 3a526d41d9af9b19d5da9c9e67ca52ad 251 SUPERFAMILY SSF89082 160 251 4.84E-15 T 28-03-2018 IPR012925 TipAS antibiotic-recognition domain CO689_RS09925 3a526d41d9af9b19d5da9c9e67ca52ad 251 SUPERFAMILY SSF46955 3 101 9.16E-25 T 28-03-2018 IPR009061 Putative DNA-binding domain CO689_RS09925 3a526d41d9af9b19d5da9c9e67ca52ad 251 Gene3D G3DSA:1.10.490.50 160 251 4.3E-16 T 28-03-2018 CO689_RS09925 3a526d41d9af9b19d5da9c9e67ca52ad 251 SMART SM00422 3 72 3.5E-17 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CO689_RS09925 3a526d41d9af9b19d5da9c9e67ca52ad 251 Pfam PF07739 TipAS antibiotic-recognition domain 131 249 5.6E-20 T 28-03-2018 IPR012925 TipAS antibiotic-recognition domain CO689_RS09925 3a526d41d9af9b19d5da9c9e67ca52ad 251 ProSitePatterns PS00552 MerR-type HTH domain signature. 6 28 - T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CO689_RS09925 3a526d41d9af9b19d5da9c9e67ca52ad 251 Gene3D G3DSA:1.10.1660.10 1 140 3.5E-27 T 28-03-2018 CO689_RS08945 9ab8ccafe20b7250d25bf842a52f6e68 318 SMART SM00382 26 213 7.1E-17 T 28-03-2018 IPR003593 AAA+ ATPase domain CO689_RS08945 9ab8ccafe20b7250d25bf842a52f6e68 318 SUPERFAMILY SSF52540 1 241 3.28E-79 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CO689_RS08945 9ab8ccafe20b7250d25bf842a52f6e68 318 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CO689_RS08945 9ab8ccafe20b7250d25bf842a52f6e68 318 Gene3D G3DSA:3.40.50.300 1 267 2.0E-78 T 28-03-2018 CO689_RS08945 9ab8ccafe20b7250d25bf842a52f6e68 318 Pfam PF00005 ABC transporter 18 163 9.3E-32 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CO689_RS00855 00ba968e339c02f7ef8bfc698b078a2d 166 Pfam PF08534 Redoxin 20 159 1.3E-25 T 28-03-2018 IPR013740 Redoxin GO:0016491 Reactome: R-HSA-3299685|Reactome: R-HSA-5628897 CO689_RS00855 00ba968e339c02f7ef8bfc698b078a2d 166 Hamap MF_00269 Probable thiol peroxidase [tpx]. 3 163 36.22 T 28-03-2018 IPR002065 Putative thiol peroxidase Tpx GO:0008379|GO:0016209|GO:0055114 CO689_RS00855 00ba968e339c02f7ef8bfc698b078a2d 166 ProSitePatterns PS01265 Tpx family signature. 83 94 - T 28-03-2018 IPR018219 Thiol peroxidase conserved site GO:0016684|GO:0055114 CO689_RS00855 00ba968e339c02f7ef8bfc698b078a2d 166 Gene3D G3DSA:3.40.30.10 12 165 8.3E-27 T 28-03-2018 CO689_RS00855 00ba968e339c02f7ef8bfc698b078a2d 166 SUPERFAMILY SSF52833 1 160 1.48E-44 T 28-03-2018 IPR012336 Thioredoxin-like fold CO689_RS08195 882c49d4ed74522a0d295f749d899f09 221 SUPERFAMILY SSF102588 5 217 5.36E-48 T 28-03-2018 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 CO689_RS08195 882c49d4ed74522a0d295f749d899f09 221 Gene3D G3DSA:3.40.50.10320 2 220 2.0E-42 T 28-03-2018 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 CO689_RS08195 882c49d4ed74522a0d295f749d899f09 221 Pfam PF02585 GlcNAc-PI de-N-acetylase 8 136 7.2E-27 T 28-03-2018 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related Reactome: R-HSA-162710 CO689_RS08195 882c49d4ed74522a0d295f749d899f09 221 TIGRFAM TIGR04000 thiol_BshB2: bacillithiol biosynthesis deacetylase BshB2 5 219 2.4E-101 T 28-03-2018 IPR023841 Bacillithiol biosynthesis deacetylase BshB2 CO689_RS10235 a18e28e00470b0abab2b8bcbf037e264 388 Pfam PF14731 Staphopain proregion 43 206 1.2E-41 T 28-03-2018 IPR028076 Staphopain proregion CO689_RS10235 a18e28e00470b0abab2b8bcbf037e264 388 SUPERFAMILY SSF54403 42 208 8.33E-45 T 28-03-2018 CO689_RS10235 a18e28e00470b0abab2b8bcbf037e264 388 Pfam PF05543 Staphopain peptidase C47 217 388 1.2E-90 T 28-03-2018 IPR008750 Staphopain peptidase C47 GO:0006508|GO:0008234 CO689_RS10235 a18e28e00470b0abab2b8bcbf037e264 388 ProSitePatterns PS00639 Eukaryotic thiol (cysteine) proteases histidine active site. 332 342 - T 28-03-2018 IPR025660 Cysteine peptidase, histidine active site Reactome: R-HSA-2132295 CO689_RS10235 a18e28e00470b0abab2b8bcbf037e264 388 SUPERFAMILY SSF54001 217 388 1.1E-78 T 28-03-2018 CO689_RS10235 a18e28e00470b0abab2b8bcbf037e264 388 Gene3D G3DSA:3.10.500.10 40 204 2.0E-45 T 28-03-2018 IPR028076 Staphopain proregion CO689_RS10235 a18e28e00470b0abab2b8bcbf037e264 388 Gene3D G3DSA:3.90.70.10 206 388 2.7E-20 T 28-03-2018 CO689_RS03315 36a7f4b0f31f0a08e873321158f8ac2e 333 SUPERFAMILY SSF69572 3 323 4.45E-80 T 28-03-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 CO689_RS03315 36a7f4b0f31f0a08e873321158f8ac2e 333 Pfam PF00899 ThiF family 5 238 5.2E-55 T 28-03-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 CO689_RS03315 36a7f4b0f31f0a08e873321158f8ac2e 333 Gene3D G3DSA:3.40.50.720 1 243 9.0E-56 T 28-03-2018 CO689_RS03325 b6cf65e3d8be679ca5ecf82d556f657c 223 Gene3D G3DSA:1.10.3720.10 4 218 1.1E-33 T 28-03-2018 CO689_RS03325 b6cf65e3d8be679ca5ecf82d556f657c 223 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 23 208 8.4E-19 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CO689_RS03325 b6cf65e3d8be679ca5ecf82d556f657c 223 TIGRFAM TIGR02141 modB_ABC: molybdate ABC transporter, permease protein 8 216 1.9E-73 T 28-03-2018 IPR011867 Molybdate ABC transporter, permease protein GO:0015098|GO:0015689|GO:0016021 CO689_RS03325 b6cf65e3d8be679ca5ecf82d556f657c 223 SUPERFAMILY SSF161098 5 211 1.09E-44 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CO689_RS10315 b5361b4b5429f787270342a12b1e1e49 400 Gene3D G3DSA:1.20.1250.20 10 202 4.7E-17 T 28-03-2018 CO689_RS10315 b5361b4b5429f787270342a12b1e1e49 400 Gene3D G3DSA:1.20.1250.20 203 396 2.9E-21 T 28-03-2018 CO689_RS10315 b5361b4b5429f787270342a12b1e1e49 400 PRINTS PR01035 Tetracycline resistance protein signature 221 237 6.4E-5 T 28-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CO689_RS10315 b5361b4b5429f787270342a12b1e1e49 400 PRINTS PR01035 Tetracycline resistance protein signature 340 362 6.4E-5 T 28-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CO689_RS10315 b5361b4b5429f787270342a12b1e1e49 400 Pfam PF07690 Major Facilitator Superfamily 22 353 4.9E-28 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CO689_RS10315 b5361b4b5429f787270342a12b1e1e49 400 SUPERFAMILY SSF103473 14 395 1.44E-41 T 28-03-2018 IPR020846 Major facilitator superfamily domain CO689_RS11630 dae90685b1fff23c943340549f9ad0e8 388 TIGRFAM TIGR01016 sucCoAbeta: succinate-CoA ligase, beta subunit 1 385 9.1E-169 T 28-03-2018 IPR005809 Succinate--CoA synthetase, beta subunit GO:0006099 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 CO689_RS11630 dae90685b1fff23c943340549f9ad0e8 388 SUPERFAMILY SSF52210 239 386 2.49E-53 T 28-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CO689_RS11630 dae90685b1fff23c943340549f9ad0e8 388 PIRSF PIRSF001554 1 388 1.1E-158 T 28-03-2018 IPR005809 Succinate--CoA synthetase, beta subunit GO:0006099 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 CO689_RS11630 dae90685b1fff23c943340549f9ad0e8 388 Gene3D G3DSA:3.40.50.261 240 385 1.5E-42 T 28-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CO689_RS11630 dae90685b1fff23c943340549f9ad0e8 388 Hamap MF_00558 Succinate--CoA ligase [ADP-forming] subunit beta [sucC]. 1 386 45.11 T 28-03-2018 IPR005809 Succinate--CoA synthetase, beta subunit GO:0006099 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 CO689_RS11630 dae90685b1fff23c943340549f9ad0e8 388 SUPERFAMILY SSF56059 1 238 7.27E-85 T 28-03-2018 CO689_RS11630 dae90685b1fff23c943340549f9ad0e8 388 ProSitePatterns PS01217 ATP-citrate lyase / succinyl-CoA ligases family signature 3. 257 281 - T 28-03-2018 IPR017866 Succinyl-CoA synthetase, beta subunit, conserved site KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CO689_RS11630 dae90685b1fff23c943340549f9ad0e8 388 Pfam PF00549 CoA-ligase 262 380 4.5E-24 T 28-03-2018 IPR005811 ATP-citrate lyase/succinyl-CoA ligase GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CO689_RS11630 dae90685b1fff23c943340549f9ad0e8 388 Gene3D G3DSA:3.30.1490.20 21 96 2.1E-25 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CO689_RS11630 dae90685b1fff23c943340549f9ad0e8 388 Gene3D G3DSA:3.30.470.20 97 239 5.5E-58 T 28-03-2018 CO689_RS11630 dae90685b1fff23c943340549f9ad0e8 388 Pfam PF08442 ATP-grasp domain 2 202 1.4E-84 T 28-03-2018 IPR013650 ATP-grasp fold, succinyl-CoA synthetase-type KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 CO689_RS12340 fc9f69797929f8bc94af23e2884c29df 259 ProSitePatterns PS00614 Indole-3-glycerol phosphate synthase signature. 50 64 - T 28-03-2018 IPR001468 Indole-3-glycerol phosphate synthase, conserved site GO:0004425|GO:0006568 KEGG: 00400+4.1.1.48 CO689_RS12340 fc9f69797929f8bc94af23e2884c29df 259 SUPERFAMILY SSF51366 1 253 2.07E-71 T 28-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 CO689_RS12340 fc9f69797929f8bc94af23e2884c29df 259 Hamap MF_00134_B Indole-3-glycerol phosphate synthase [trpC]. 2 255 33.041 T 28-03-2018 IPR013798 Indole-3-glycerol phosphate synthase GO:0004425 KEGG: 00400+4.1.1.48 CO689_RS12340 fc9f69797929f8bc94af23e2884c29df 259 Pfam PF00218 Indole-3-glycerol phosphate synthase 4 251 1.7E-75 T 28-03-2018 IPR013798 Indole-3-glycerol phosphate synthase GO:0004425 KEGG: 00400+4.1.1.48 CO689_RS12340 fc9f69797929f8bc94af23e2884c29df 259 Gene3D G3DSA:3.20.20.70 4 256 5.6E-60 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CO689_RS03870 c3ec787b1e802165b82c0470ed9667fd 187 TIGRFAM TIGR00730 TIGR00730: TIGR00730 family protein 3 173 1.2E-49 T 28-03-2018 IPR005269 Cytokinin riboside 5'-monophosphate phosphoribohydrolase LOG CO689_RS03870 c3ec787b1e802165b82c0470ed9667fd 187 SUPERFAMILY SSF102405 1 178 7.94E-59 T 28-03-2018 CO689_RS03870 c3ec787b1e802165b82c0470ed9667fd 187 Pfam PF03641 Possible lysine decarboxylase 45 172 1.4E-36 T 28-03-2018 IPR031100 LOG family CO689_RS03870 c3ec787b1e802165b82c0470ed9667fd 187 Gene3D G3DSA:3.40.50.450 1 187 9.4E-53 T 28-03-2018 CO689_RS11940 993247346fb8580dd7a8f6342431c72a 513 SUPERFAMILY SSF102114 199 432 5.1E-61 T 28-03-2018 CO689_RS11940 993247346fb8580dd7a8f6342431c72a 513 TIGRFAM TIGR01574 miaB-methiolase: tRNA-i(6)A37 thiotransferase enzyme MiaB 68 501 2.1E-191 T 28-03-2018 CO689_RS11940 993247346fb8580dd7a8f6342431c72a 513 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 216 236 - T 28-03-2018 IPR020612 Methylthiotransferase, conserved site GO:0051539 CO689_RS11940 993247346fb8580dd7a8f6342431c72a 513 Gene3D G3DSA:3.80.30.20 209 443 5.9E-53 T 28-03-2018 IPR023404 Radical SAM, alpha/beta horseshoe CO689_RS11940 993247346fb8580dd7a8f6342431c72a 513 SMART SM00729 212 430 4.1E-64 T 28-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 CO689_RS11940 993247346fb8580dd7a8f6342431c72a 513 Pfam PF01938 TRAM domain 441 503 7.9E-14 T 28-03-2018 IPR002792 TRAM domain CO689_RS11940 993247346fb8580dd7a8f6342431c72a 513 Pfam PF00919 Uncharacterized protein family UPF0004 69 169 2.8E-29 T 28-03-2018 IPR013848 Methylthiotransferase, N-terminal GO:0051539 CO689_RS11940 993247346fb8580dd7a8f6342431c72a 513 Pfam PF04055 Radical SAM superfamily 216 387 1.4E-33 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CO689_RS11940 993247346fb8580dd7a8f6342431c72a 513 Hamap MF_01864 tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase [miaB]. 67 503 69.804 T 28-03-2018 IPR006463 tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase MiaB GO:0005737|GO:0006400|GO:0016740|GO:0051539 CO689_RS11940 993247346fb8580dd7a8f6342431c72a 513 TIGRFAM TIGR00089 TIGR00089: radical SAM methylthiotransferase, MiaB/RimO family 68 500 3.4E-157 T 28-03-2018 IPR005839 Methylthiotransferase GO:0006400|GO:0016740|GO:0051539 CO689_RS06295 6e0c4157af55bb8b622831822c38e85f 351 Gene3D G3DSA:3.40.250.10 5 98 1.5E-24 T 28-03-2018 IPR001763 Rhodanese-like domain CO689_RS06295 6e0c4157af55bb8b622831822c38e85f 351 SUPERFAMILY SSF75169 199 243 1.24E-18 T 28-03-2018 IPR027396 DsrEFH-like CO689_RS06295 6e0c4157af55bb8b622831822c38e85f 351 SUPERFAMILY SSF75169 293 341 1.24E-18 T 28-03-2018 IPR027396 DsrEFH-like CO689_RS06295 6e0c4157af55bb8b622831822c38e85f 351 SUPERFAMILY SSF52821 10 96 2.88E-27 T 28-03-2018 IPR001763 Rhodanese-like domain CO689_RS06295 6e0c4157af55bb8b622831822c38e85f 351 Gene3D G3DSA:3.30.110.40 99 185 5.7E-26 T 28-03-2018 IPR001455 TusA-like domain CO689_RS06295 6e0c4157af55bb8b622831822c38e85f 351 SUPERFAMILY SSF64307 98 184 1.18E-18 T 28-03-2018 IPR001455 TusA-like domain CO689_RS06295 6e0c4157af55bb8b622831822c38e85f 351 Pfam PF00581 Rhodanese-like domain 12 95 4.4E-15 T 28-03-2018 IPR001763 Rhodanese-like domain CO689_RS06295 6e0c4157af55bb8b622831822c38e85f 351 ProSitePatterns PS01148 Uncharacterized protein family UPF0033 signature. 117 141 - T 28-03-2018 IPR001455 TusA-like domain CO689_RS06295 6e0c4157af55bb8b622831822c38e85f 351 SMART SM00450 7 99 7.8E-22 T 28-03-2018 IPR001763 Rhodanese-like domain CO689_RS06295 6e0c4157af55bb8b622831822c38e85f 351 Pfam PF01206 Sulfurtransferase TusA 115 184 4.0E-18 T 28-03-2018 IPR001455 TusA-like domain CO689_RS06295 6e0c4157af55bb8b622831822c38e85f 351 Gene3D G3DSA:3.40.1260.10 190 351 9.1E-51 T 28-03-2018 CO689_RS06295 6e0c4157af55bb8b622831822c38e85f 351 Pfam PF13686 DsrE/DsrF/DrsH-like family 198 350 1.9E-56 T 28-03-2018 IPR032836 DsrE2-like family CO689_RS07495 c04e0ded28ca76f5d7a50e803a235ee1 548 Pfam PF11941 Domain of unknown function (DUF3459) 460 532 4.9E-7 T 28-03-2018 IPR022567 Glycosyl hydrolase, C-terminal (DUF3459) CO689_RS07495 c04e0ded28ca76f5d7a50e803a235ee1 548 Gene3D G3DSA:2.60.40.1180 475 516 2.1E-10 T 28-03-2018 CO689_RS07495 c04e0ded28ca76f5d7a50e803a235ee1 548 SUPERFAMILY SSF51445 5 473 1.62E-154 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CO689_RS07495 c04e0ded28ca76f5d7a50e803a235ee1 548 Gene3D G3DSA:3.90.400.10 120 170 2.0E-28 T 28-03-2018 CO689_RS07495 c04e0ded28ca76f5d7a50e803a235ee1 548 SUPERFAMILY SSF51011 476 527 5.76E-9 T 28-03-2018 CO689_RS07495 c04e0ded28ca76f5d7a50e803a235ee1 548 SMART SM00642 13 415 2.9E-158 T 28-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CO689_RS07495 c04e0ded28ca76f5d7a50e803a235ee1 548 Gene3D G3DSA:3.20.20.80 340 469 4.8E-24 T 28-03-2018 CO689_RS07495 c04e0ded28ca76f5d7a50e803a235ee1 548 Gene3D G3DSA:3.20.20.470 171 339 6.4E-40 T 28-03-2018 CO689_RS07495 c04e0ded28ca76f5d7a50e803a235ee1 548 Gene3D G3DSA:3.20.20.80 2 119 1.9E-44 T 28-03-2018 CO689_RS07495 c04e0ded28ca76f5d7a50e803a235ee1 548 Pfam PF00128 Alpha amylase, catalytic domain 28 373 1.6E-124 T 28-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CO689_RS07495 c04e0ded28ca76f5d7a50e803a235ee1 548 TIGRFAM TIGR02403 trehalose_treC: alpha,alpha-phosphotrehalase 6 525 8.7E-247 T 28-03-2018 IPR012769 Trehalose-6-phosphate hydrolase GO:0005737|GO:0005993|GO:0008788 KEGG: 00500+3.2.1.93 CO689_RS07050 0eb6064bad980f0be30ae06232988b77 240 Hamap MF_00074 Ribosomal RNA small subunit methyltransferase G [rsmG]. 14 215 28.553 T 28-03-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 CO689_RS07050 0eb6064bad980f0be30ae06232988b77 240 Gene3D G3DSA:3.40.50.150 2 239 2.1E-44 T 28-03-2018 CO689_RS07050 0eb6064bad980f0be30ae06232988b77 240 Pfam PF02527 rRNA small subunit methyltransferase G 21 204 3.1E-57 T 28-03-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 CO689_RS07050 0eb6064bad980f0be30ae06232988b77 240 SUPERFAMILY SSF53335 3 238 3.5E-48 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CO689_RS07050 0eb6064bad980f0be30ae06232988b77 240 PIRSF PIRSF003078 1 221 8.2E-59 T 28-03-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 CO689_RS07050 0eb6064bad980f0be30ae06232988b77 240 TIGRFAM TIGR00138 rsmG_gidB: 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG 25 218 3.7E-51 T 28-03-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 CO689_RS08115 9ea57047ad8790ec8c032ce14e2de11c 320 Gene3D G3DSA:3.40.50.720 1 319 3.2E-40 T 28-03-2018 CO689_RS08115 9ea57047ad8790ec8c032ce14e2de11c 320 SUPERFAMILY SSF51735 1 314 2.45E-55 T 28-03-2018 IPR016040 NAD(P)-binding domain CO689_RS08115 9ea57047ad8790ec8c032ce14e2de11c 320 Pfam PF01370 NAD dependent epimerase/dehydratase family 4 240 1.8E-27 T 28-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 CO689_RS04295 38368e20ec8de5f45b49933c4d4df9df 650 PIRSF PIRSF000906 5 650 0.0 T 28-03-2018 IPR009164 Fructose-1,6-bisphosphatase class 3 GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 CO689_RS04295 38368e20ec8de5f45b49933c4d4df9df 650 Hamap MF_01854 Fructose-1,6-bisphosphatase class 3 [fbp]. 9 650 38.185 T 28-03-2018 IPR009164 Fructose-1,6-bisphosphatase class 3 GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 CO689_RS04295 38368e20ec8de5f45b49933c4d4df9df 650 Gene3D G3DSA:3.60.21.10 1 604 5.9E-46 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CO689_RS04295 38368e20ec8de5f45b49933c4d4df9df 650 SUPERFAMILY SSF56300 394 428 3.65E-10 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CO689_RS04295 38368e20ec8de5f45b49933c4d4df9df 650 SUPERFAMILY SSF56300 194 265 3.65E-10 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CO689_RS04295 38368e20ec8de5f45b49933c4d4df9df 650 SUPERFAMILY SSF56300 515 564 3.65E-10 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CO689_RS04295 38368e20ec8de5f45b49933c4d4df9df 650 SUPERFAMILY SSF56300 461 477 3.65E-10 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CO689_RS04295 38368e20ec8de5f45b49933c4d4df9df 650 Pfam PF06874 Firmicute fructose-1,6-bisphosphatase 11 645 3.1E-278 T 28-03-2018 IPR009164 Fructose-1,6-bisphosphatase class 3 GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 CO689_RS06220 2a1554effe8ffc8531f520468ba7c52b 465 Gene3D G3DSA:1.20.1250.20 1 202 9.6E-32 T 28-03-2018 CO689_RS06220 2a1554effe8ffc8531f520468ba7c52b 465 SUPERFAMILY SSF103473 252 460 3.4E-55 T 28-03-2018 IPR020846 Major facilitator superfamily domain CO689_RS06220 2a1554effe8ffc8531f520468ba7c52b 465 SUPERFAMILY SSF103473 12 199 3.4E-55 T 28-03-2018 IPR020846 Major facilitator superfamily domain CO689_RS06220 2a1554effe8ffc8531f520468ba7c52b 465 Gene3D G3DSA:1.20.1250.20 262 465 5.3E-18 T 28-03-2018 CO689_RS06220 2a1554effe8ffc8531f520468ba7c52b 465 Pfam PF07690 Major Facilitator Superfamily 22 414 1.1E-49 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CO689_RS06385 44436fb2d806621f4a37cc16c0e50bfe 116 Gene3D G3DSA:1.10.1660.10 60 116 6.9E-6 T 28-03-2018 CO689_RS06385 44436fb2d806621f4a37cc16c0e50bfe 116 Gene3D G3DSA:1.10.1660.10 1 59 3.0E-17 T 28-03-2018 CO689_RS06385 44436fb2d806621f4a37cc16c0e50bfe 116 Pfam PF13411 MerR HTH family regulatory protein 4 72 3.5E-16 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CO689_RS06385 44436fb2d806621f4a37cc16c0e50bfe 116 SMART SM00422 4 73 1.3E-14 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CO689_RS06385 44436fb2d806621f4a37cc16c0e50bfe 116 SUPERFAMILY SSF46955 4 112 6.59E-24 T 28-03-2018 IPR009061 Putative DNA-binding domain CO689_RS03335 275dafdd8338a5cae5d31f3438a04ead 497 Pfam PF02744 Galactose-1-phosphate uridyl transferase, C-terminal domain 247 440 1.2E-30 T 28-03-2018 IPR005850 Galactose-1-phosphate uridyl transferase, C-terminal GO:0006012|GO:0008108 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-70370 CO689_RS03335 275dafdd8338a5cae5d31f3438a04ead 497 TIGRFAM TIGR01239 galT_2: galactose-1-phosphate uridylyltransferase 8 497 3.7E-231 T 28-03-2018 IPR000766 Galactose-1-phosphate uridyl transferase, class II GO:0005737|GO:0006012|GO:0008108 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527 CO689_RS03335 275dafdd8338a5cae5d31f3438a04ead 497 PIRSF PIRSF006005 2 497 2.7E-218 T 28-03-2018 IPR000766 Galactose-1-phosphate uridyl transferase, class II GO:0005737|GO:0006012|GO:0008108 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527 CO689_RS03335 275dafdd8338a5cae5d31f3438a04ead 497 Hamap MF_00571 Galactose-1-phosphate uridylyltransferase [galT]. 1 497 249.382 T 28-03-2018 IPR000766 Galactose-1-phosphate uridyl transferase, class II GO:0005737|GO:0006012|GO:0008108 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527 CO689_RS03335 275dafdd8338a5cae5d31f3438a04ead 497 ProSitePatterns PS01163 Galactose-1-phosphate uridyl transferase family 2 signature. 260 277 - T 28-03-2018 IPR023425 Galactose-1-phosphate uridyl transferase, class II, conserved site GO:0008108 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527 CO689_RS03335 275dafdd8338a5cae5d31f3438a04ead 497 Pfam PF01087 Galactose-1-phosphate uridyl transferase, N-terminal domain 21 232 8.8E-28 T 28-03-2018 IPR005849 Galactose-1-phosphate uridyl transferase, N-terminal GO:0006012|GO:0008108 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-70370 CO689_RS05825 f8802bf27664a55f8108400f497bf1c9 391 Gene3D G3DSA:3.90.1510.10 45 279 6.6E-92 T 28-03-2018 IPR018193 Glycerate kinase, flavodoxin-like domain GO:0008887|GO:0031388 CO689_RS05825 f8802bf27664a55f8108400f497bf1c9 391 SUPERFAMILY SSF110738 4 350 1.7E-123 T 28-03-2018 IPR004381 Glycerate kinase GO:0008887|GO:0031388 CO689_RS05825 f8802bf27664a55f8108400f497bf1c9 391 TIGRFAM TIGR00045 TIGR00045: glycerate kinase 4 349 2.8E-143 T 28-03-2018 IPR004381 Glycerate kinase GO:0008887|GO:0031388 CO689_RS05825 f8802bf27664a55f8108400f497bf1c9 391 Pfam PF02595 Glycerate kinase family 5 349 3.6E-136 T 28-03-2018 IPR004381 Glycerate kinase GO:0008887|GO:0031388 CO689_RS05825 f8802bf27664a55f8108400f497bf1c9 391 PIRSF PIRSF006078 3 385 1.0E-133 T 28-03-2018 IPR004381 Glycerate kinase GO:0008887|GO:0031388 CO689_RS10280 91d2c29b63c6ebba86eeaa1e991506e2 620 Pfam PF02080 TrkA-C domain 555 610 1.1E-9 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 CO689_RS10280 91d2c29b63c6ebba86eeaa1e991506e2 620 SUPERFAMILY SSF116726 541 610 1.02E-9 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 CO689_RS10280 91d2c29b63c6ebba86eeaa1e991506e2 620 Gene3D G3DSA:3.40.50.720 395 518 1.8E-5 T 28-03-2018 CO689_RS10280 91d2c29b63c6ebba86eeaa1e991506e2 620 Gene3D G3DSA:1.20.91.10 241 326 4.6E-17 T 28-03-2018 CO689_RS10280 91d2c29b63c6ebba86eeaa1e991506e2 620 SUPERFAMILY SSF51735 406 500 2.05E-8 T 28-03-2018 IPR016040 NAD(P)-binding domain CO689_RS10280 91d2c29b63c6ebba86eeaa1e991506e2 620 Pfam PF00999 Sodium/hydrogen exchanger family 7 388 2.2E-72 T 28-03-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 CO689_RS10280 91d2c29b63c6ebba86eeaa1e991506e2 620 Pfam PF02254 TrkA-N domain 445 513 1.6E-5 T 28-03-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 CO689_RS10280 91d2c29b63c6ebba86eeaa1e991506e2 620 Gene3D G3DSA:3.30.70.1450 538 614 3.6E-10 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 CO689_RS10045 daa44d4f22ceb9b13410ffd670c17f21 128 Gene3D G3DSA:2.40.50.140 3 106 2.0E-24 T 28-03-2018 CO689_RS10045 daa44d4f22ceb9b13410ffd670c17f21 128 SUPERFAMILY SSF50249 5 89 2.79E-20 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CO689_RS10045 daa44d4f22ceb9b13410ffd670c17f21 128 Pfam PF00575 S1 RNA binding domain 6 76 1.8E-14 T 28-03-2018 IPR003029 S1 domain GO:0003676 CO689_RS10045 daa44d4f22ceb9b13410ffd670c17f21 128 SMART SM00316 6 76 1.4E-21 T 28-03-2018 IPR022967 RNA-binding domain, S1 CO689_RS12385 527060718f0f5de90aa4319b1222a804 272 SUPERFAMILY SSF161098 64 250 1.57E-25 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CO689_RS12385 527060718f0f5de90aa4319b1222a804 272 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 86 267 2.1E-28 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CO689_RS12385 527060718f0f5de90aa4319b1222a804 272 Gene3D G3DSA:1.10.3720.10 3 258 6.8E-40 T 28-03-2018 CO689_RS04400 b9721d90aa4db042b9b8ecc702d2370e 234 Pfam PF03591 AzlC protein 19 158 8.2E-38 T 28-03-2018 IPR011606 Branched-chain amino acid transport, permease CO689_RS04260 96ba784403bdbebe8814e0bb684d4e9a 641 Pfam PF13515 Fusaric acid resistance protein-like 349 473 2.7E-20 T 28-03-2018 CO689_RS13530 ad354725745b2678fd4e3ec2c3687796 86 SMART SM01323 1 84 2.6E-35 T 28-03-2018 IPR003849 Preprotein translocase YajC CO689_RS13530 ad354725745b2678fd4e3ec2c3687796 86 Pfam PF02699 Preprotein translocase subunit 6 81 1.5E-27 T 28-03-2018 IPR003849 Preprotein translocase YajC CO689_RS13530 ad354725745b2678fd4e3ec2c3687796 86 TIGRFAM TIGR00739 yajC: preprotein translocase, YajC subunit 6 83 2.2E-24 T 28-03-2018 IPR003849 Preprotein translocase YajC CO689_RS13530 ad354725745b2678fd4e3ec2c3687796 86 PRINTS PR01853 Bacterial YajC preprotein translocase signature 3 23 6.3E-10 T 28-03-2018 IPR003849 Preprotein translocase YajC CO689_RS13530 ad354725745b2678fd4e3ec2c3687796 86 PRINTS PR01853 Bacterial YajC preprotein translocase signature 23 41 6.3E-10 T 28-03-2018 IPR003849 Preprotein translocase YajC CO689_RS07350 3af55d55a019c5f34e0ae906e58fe4fe 107 SUPERFAMILY SSF46785 4 97 1.8E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS07350 3af55d55a019c5f34e0ae906e58fe4fe 107 Gene3D G3DSA:1.10.10.10 1 107 2.6E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS07350 3af55d55a019c5f34e0ae906e58fe4fe 107 Pfam PF03551 Transcriptional regulator PadR-like family 14 83 7.8E-20 T 28-03-2018 IPR005149 Transcription regulator PadR, N-terminal CO689_RS03120 70025c60935d9039637908c6cab25f48 217 Pfam PF00189 Ribosomal protein S3, C-terminal domain 119 201 1.0E-37 T 28-03-2018 IPR001351 Ribosomal protein S3, C-terminal GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CO689_RS03120 70025c60935d9039637908c6cab25f48 217 SUPERFAMILY SSF54814 2 105 1.94E-38 T 28-03-2018 IPR009019 K homology domain, prokaryotic type GO:0003723 CO689_RS03120 70025c60935d9039637908c6cab25f48 217 SMART SM00322 59 124 3.9E-9 T 28-03-2018 IPR004087 K Homology domain GO:0003676 CO689_RS03120 70025c60935d9039637908c6cab25f48 217 Hamap MF_01309_B 30S ribosomal protein S3 [rpsC]. 1 205 37.58 T 28-03-2018 IPR005704 Ribosomal protein S3, bacterial GO:0003735|GO:0006412|GO:0015935 CO689_RS03120 70025c60935d9039637908c6cab25f48 217 TIGRFAM TIGR01009 rpsC_bact: ribosomal protein uS3 1 208 3.4E-93 T 28-03-2018 IPR005704 Ribosomal protein S3, bacterial GO:0003735|GO:0006412|GO:0015935 CO689_RS03120 70025c60935d9039637908c6cab25f48 217 ProSitePatterns PS00548 Ribosomal protein S3 signature. 162 196 - T 28-03-2018 IPR018280 Ribosomal protein S3, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CO689_RS03120 70025c60935d9039637908c6cab25f48 217 SUPERFAMILY SSF54821 106 205 2.88E-37 T 28-03-2018 IPR001351 Ribosomal protein S3, C-terminal GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CO689_RS03120 70025c60935d9039637908c6cab25f48 217 Pfam PF07650 KH domain 37 108 1.1E-20 T 28-03-2018 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CO689_RS03120 70025c60935d9039637908c6cab25f48 217 Gene3D G3DSA:3.30.300.20 17 106 4.5E-31 T 28-03-2018 IPR015946 K homology domain-like, alpha/beta CO689_RS03120 70025c60935d9039637908c6cab25f48 217 Gene3D G3DSA:3.30.1140.32 107 206 7.4E-35 T 28-03-2018 CO689_RS10880 cda327df5a26ca4fda63f460393722ca 91 PIRSF PIRSF037260 1 91 2.5E-38 T 28-03-2018 IPR007920 Protein of unknown function UPF0223 CO689_RS10880 cda327df5a26ca4fda63f460393722ca 91 SUPERFAMILY SSF158504 4 84 1.57E-32 T 28-03-2018 IPR023324 BH2638-like domain CO689_RS10880 cda327df5a26ca4fda63f460393722ca 91 Pfam PF05256 Uncharacterised protein family (UPF0223) 2 85 9.4E-36 T 28-03-2018 IPR007920 Protein of unknown function UPF0223 CO689_RS10880 cda327df5a26ca4fda63f460393722ca 91 Gene3D G3DSA:1.10.220.80 12 88 5.7E-30 T 28-03-2018 IPR023324 BH2638-like domain CO689_RS10880 cda327df5a26ca4fda63f460393722ca 91 Hamap MF_01041 UPF0223 protein . 1 89 24.999 T 28-03-2018 IPR007920 Protein of unknown function UPF0223 CO689_RS10880 cda327df5a26ca4fda63f460393722ca 91 ProDom PD062738 UPF0223 FAMILY UNCHARACTERISED CYTOSOLIC SUPERFAMILY YKTA LMO1058/LIN1050 INOSITOL MW0980 M6_SPY0948 1 83 6.0E-26 T 28-03-2018 IPR007920 Protein of unknown function UPF0223 CO689_RS09135 87624fe697f24f7416bb402e78f3d784 949 SUPERFAMILY SSF52540 15 208 6.75E-44 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CO689_RS09135 87624fe697f24f7416bb402e78f3d784 949 SUPERFAMILY SSF52540 432 571 6.75E-44 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CO689_RS09135 87624fe697f24f7416bb402e78f3d784 949 Pfam PF00005 ABC transporter 624 860 2.5E-9 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CO689_RS09135 87624fe697f24f7416bb402e78f3d784 949 Gene3D G3DSA:3.40.50.300 419 618 2.7E-22 T 28-03-2018 CO689_RS09135 87624fe697f24f7416bb402e78f3d784 949 ProSitePatterns PS00211 ABC transporters family signature. 830 844 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CO689_RS09135 87624fe697f24f7416bb402e78f3d784 949 ProSitePatterns PS00211 ABC transporters family signature. 489 503 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CO689_RS09135 87624fe697f24f7416bb402e78f3d784 949 Gene3D G3DSA:3.40.50.300 1 117 5.8E-14 T 28-03-2018 CO689_RS09135 87624fe697f24f7416bb402e78f3d784 949 Hamap MF_00205 UvrABC system protein A [uvrA]. 5 940 23.282 T 28-03-2018 IPR004602 UvrABC system subunit A GO:0006289|GO:0009380|GO:0009381 CO689_RS09135 87624fe697f24f7416bb402e78f3d784 949 SUPERFAMILY SSF52540 615 914 8.72E-52 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CO689_RS09135 87624fe697f24f7416bb402e78f3d784 949 TIGRFAM TIGR00630 uvra: excinuclease ABC subunit A 8 925 0.0 T 28-03-2018 IPR004602 UvrABC system subunit A GO:0006289|GO:0009380|GO:0009381 CO689_RS09135 87624fe697f24f7416bb402e78f3d784 949 Gene3D G3DSA:1.10.8.280 286 407 4.2E-41 T 28-03-2018 CO689_RS09135 87624fe697f24f7416bb402e78f3d784 949 Gene3D G3DSA:3.40.50.300 619 949 7.4E-57 T 28-03-2018 CO689_RS09135 87624fe697f24f7416bb402e78f3d784 949 Gene3D G3DSA:3.30.190.20 131 249 3.3E-44 T 28-03-2018 CO689_RS01845 f47db868d146de91ff92f0978afca57d 189 Hamap MF_01515 UPF0316 protein . 9 177 30.416 T 28-03-2018 IPR022930 Protein of unknown function UPF0316 CO689_RS01845 f47db868d146de91ff92f0978afca57d 189 Pfam PF10035 Uncharacterized protein conserved in bacteria (DUF2179) 117 169 9.1E-8 T 28-03-2018 IPR019264 Domain of unknown function DUF2179 CO689_RS02945 f4f20b0dde4bdd075c09591700be5dec 71 SUPERFAMILY SSF55008 1 68 1.96E-18 T 28-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 CO689_RS02945 f4f20b0dde4bdd075c09591700be5dec 71 Gene3D G3DSA:3.30.70.100 1 70 1.2E-19 T 28-03-2018 CO689_RS02945 f4f20b0dde4bdd075c09591700be5dec 71 PRINTS PR00942 Copper-transporting ATPase 1 signature 29 52 1.8E-8 T 28-03-2018 CO689_RS02945 f4f20b0dde4bdd075c09591700be5dec 71 PRINTS PR00942 Copper-transporting ATPase 1 signature 58 71 1.8E-8 T 28-03-2018 CO689_RS02945 f4f20b0dde4bdd075c09591700be5dec 71 PRINTS PR00942 Copper-transporting ATPase 1 signature 3 28 1.8E-8 T 28-03-2018 CO689_RS02945 f4f20b0dde4bdd075c09591700be5dec 71 ProSitePatterns PS01047 Heavy-metal-associated domain. 8 37 - T 28-03-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 CO689_RS02945 f4f20b0dde4bdd075c09591700be5dec 71 Pfam PF00403 Heavy-metal-associated domain 7 65 2.4E-14 T 28-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 CO689_RS12590 8996f0606b6b2f097af49e9792f94839 73 Gene3D G3DSA:1.10.150.260 5 69 2.9E-23 T 28-03-2018 IPR023089 YozE SAM-like domain CO689_RS12590 8996f0606b6b2f097af49e9792f94839 73 SUPERFAMILY SSF140652 5 71 8.24E-22 T 28-03-2018 IPR023089 YozE SAM-like domain CO689_RS12590 8996f0606b6b2f097af49e9792f94839 73 Pfam PF06855 YozE SAM-like fold 5 69 1.2E-22 T 28-03-2018 IPR023089 YozE SAM-like domain CO689_RS03050 62d4f72b1f19c280443424528454ed72 430 SUPERFAMILY SSF103491 1 418 1.05E-124 T 28-03-2018 IPR023201 SecY subunit domain Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 CO689_RS03050 62d4f72b1f19c280443424528454ed72 430 PRINTS PR00303 Preprotein translocase SecY subunit signature 308 330 2.2E-99 T 28-03-2018 CO689_RS03050 62d4f72b1f19c280443424528454ed72 430 PRINTS PR00303 Preprotein translocase SecY subunit signature 268 287 2.2E-99 T 28-03-2018 CO689_RS03050 62d4f72b1f19c280443424528454ed72 430 PRINTS PR00303 Preprotein translocase SecY subunit signature 397 415 2.2E-99 T 28-03-2018 CO689_RS03050 62d4f72b1f19c280443424528454ed72 430 PRINTS PR00303 Preprotein translocase SecY subunit signature 18 36 2.2E-99 T 28-03-2018 CO689_RS03050 62d4f72b1f19c280443424528454ed72 430 PRINTS PR00303 Preprotein translocase SecY subunit signature 68 88 2.2E-99 T 28-03-2018 CO689_RS03050 62d4f72b1f19c280443424528454ed72 430 PRINTS PR00303 Preprotein translocase SecY subunit signature 147 172 2.2E-99 T 28-03-2018 CO689_RS03050 62d4f72b1f19c280443424528454ed72 430 PRINTS PR00303 Preprotein translocase SecY subunit signature 363 381 2.2E-99 T 28-03-2018 CO689_RS03050 62d4f72b1f19c280443424528454ed72 430 PRINTS PR00303 Preprotein translocase SecY subunit signature 173 196 2.2E-99 T 28-03-2018 CO689_RS03050 62d4f72b1f19c280443424528454ed72 430 PRINTS PR00303 Preprotein translocase SecY subunit signature 110 133 2.2E-99 T 28-03-2018 CO689_RS03050 62d4f72b1f19c280443424528454ed72 430 PIRSF PIRSF004557 1 428 1.2E-129 T 28-03-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 CO689_RS03050 62d4f72b1f19c280443424528454ed72 430 Gene3D G3DSA:1.10.3370.10 1 430 1.3E-150 T 28-03-2018 CO689_RS03050 62d4f72b1f19c280443424528454ed72 430 Hamap MF_01465 Protein translocase subunit SecY [secY]. 5 428 28.699 T 28-03-2018 IPR026593 Protein translocase subunit SecY CO689_RS03050 62d4f72b1f19c280443424528454ed72 430 ProSitePatterns PS00756 Protein secY signature 2. 166 183 - T 28-03-2018 IPR030659 SecY conserved site Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 CO689_RS03050 62d4f72b1f19c280443424528454ed72 430 ProSitePatterns PS00755 Protein secY signature 1. 69 88 - T 28-03-2018 IPR030659 SecY conserved site Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 CO689_RS03050 62d4f72b1f19c280443424528454ed72 430 Pfam PF00344 SecY translocase 69 412 3.7E-110 T 28-03-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 CO689_RS03050 62d4f72b1f19c280443424528454ed72 430 TIGRFAM TIGR00967 3a0501s007: preprotein translocase, SecY subunit 15 424 1.7E-149 T 28-03-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 CO689_RS07170 49ea7d1c0b4ff6ca465ebda81bd5dc50 388 ProSitePatterns PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. 67 76 - T 28-03-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 CO689_RS07170 49ea7d1c0b4ff6ca465ebda81bd5dc50 388 TIGRFAM TIGR01910 DapE-ArgE: peptidase, ArgE/DapE family 10 373 6.0E-100 T 28-03-2018 IPR010182 N-formyl-4-amino-5-aminomethyl-2-methylpyrimidine deformylase/Succinyl-diaminopimelate desuccinylase CO689_RS07170 49ea7d1c0b4ff6ca465ebda81bd5dc50 388 ProSitePatterns PS00759 ArgE / dapE / ACY1 / CPG2 / yscS family signature 2. 104 143 - T 28-03-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 CO689_RS07170 49ea7d1c0b4ff6ca465ebda81bd5dc50 388 SUPERFAMILY SSF55031 178 282 1.31E-19 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain CO689_RS07170 49ea7d1c0b4ff6ca465ebda81bd5dc50 388 Gene3D G3DSA:3.40.630.10 3 280 2.1E-68 T 28-03-2018 CO689_RS07170 49ea7d1c0b4ff6ca465ebda81bd5dc50 388 Pfam PF07687 Peptidase dimerisation domain 174 282 1.1E-21 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain CO689_RS07170 49ea7d1c0b4ff6ca465ebda81bd5dc50 388 Pfam PF01546 Peptidase family M20/M25/M40 69 380 6.7E-36 T 28-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CO689_RS07170 49ea7d1c0b4ff6ca465ebda81bd5dc50 388 SUPERFAMILY SSF53187 298 380 9.14E-62 T 28-03-2018 CO689_RS07170 49ea7d1c0b4ff6ca465ebda81bd5dc50 388 SUPERFAMILY SSF53187 6 177 9.14E-62 T 28-03-2018 CO689_RS02410 36bb1677dd8391d153f6e8e55d49bb45 138 Pfam PF00436 Single-strand binding protein family 2 101 9.5E-22 T 28-03-2018 IPR000424 Primosome PriB/single-strand DNA-binding GO:0003697 Reactome: R-HSA-2151201 CO689_RS02410 36bb1677dd8391d153f6e8e55d49bb45 138 SUPERFAMILY SSF50249 1 115 3.14E-26 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CO689_RS02410 36bb1677dd8391d153f6e8e55d49bb45 138 Gene3D G3DSA:2.40.50.140 1 110 2.0E-27 T 28-03-2018 CO689_RS02410 36bb1677dd8391d153f6e8e55d49bb45 138 TIGRFAM TIGR00621 ssb: single-stranded DNA-binding protein 1 117 1.5E-21 T 28-03-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 CO689_RS02410 36bb1677dd8391d153f6e8e55d49bb45 138 Hamap MF_00984 Single-stranded DNA-binding protein. 2 106 22.956 T 28-03-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 CO689_RS02410 36bb1677dd8391d153f6e8e55d49bb45 138 PIRSF PIRSF002070 1 134 3.3E-30 T 28-03-2018 CO689_RS03375 3516c5916771b82c282dd7eafa5d271f 381 PIRSF PIRSF016578 5 105 7.5E-9 T 28-03-2018 CO689_RS03375 3516c5916771b82c282dd7eafa5d271f 381 PIRSF PIRSF016578 138 380 9.4E-22 T 28-03-2018 CO689_RS03375 3516c5916771b82c282dd7eafa5d271f 381 Gene3D G3DSA:1.10.540.10 6 123 5.8E-12 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CO689_RS03375 3516c5916771b82c282dd7eafa5d271f 381 Gene3D G3DSA:1.20.140.10 219 379 2.1E-22 T 28-03-2018 CO689_RS03375 3516c5916771b82c282dd7eafa5d271f 381 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 126 218 3.6E-15 T 28-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 CO689_RS03375 3516c5916771b82c282dd7eafa5d271f 381 Gene3D G3DSA:2.40.110.10 124 218 3.0E-20 T 28-03-2018 CO689_RS03375 3516c5916771b82c282dd7eafa5d271f 381 SUPERFAMILY SSF47203 236 380 7.73E-26 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CO689_RS03375 3516c5916771b82c282dd7eafa5d271f 381 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 22 98 4.7E-7 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CO689_RS03375 3516c5916771b82c282dd7eafa5d271f 381 Pfam PF08028 Acyl-CoA dehydrogenase, C-terminal domain 244 359 1.7E-14 T 28-03-2018 IPR013107 Acyl-CoA dehydrogenase, C-terminal domain CO689_RS03375 3516c5916771b82c282dd7eafa5d271f 381 SUPERFAMILY SSF56645 22 226 6.81E-41 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CO689_RS11870 75f1f6ddbcca4d95f94aa5c64e45a211 331 Pfam PF03601 Conserved hypothetical protein 698 12 310 3.3E-87 T 28-03-2018 IPR018383 Uncharacterised protein family UPF0324, prokaryote GO:0016021 CO689_RS04055 fe17a3980d2f4b5d918d5e2601bd9de2 228 TIGRFAM TIGR01258 pgm_1: phosphoglycerate mutase 1 family 3 228 2.6E-103 T 28-03-2018 IPR005952 Phosphoglycerate mutase 1 GO:0004619|GO:0006096|GO:0016868 KEGG: 00010+5.4.2.11|KEGG: 00260+5.4.2.11|KEGG: 00680+5.4.2.11|MetaCyc: PWY-1622|MetaCyc: PWY-5484 CO689_RS04055 fe17a3980d2f4b5d918d5e2601bd9de2 228 ProSitePatterns PS00175 Phosphoglycerate mutase family phosphohistidine signature. 6 15 - T 28-03-2018 IPR001345 Phosphoglycerate/bisphosphoglycerate mutase, active site GO:0003824|GO:0008152 CO689_RS04055 fe17a3980d2f4b5d918d5e2601bd9de2 228 SUPERFAMILY SSF53254 1 224 6.0E-67 T 28-03-2018 IPR029033 Histidine phosphatase superfamily CO689_RS04055 fe17a3980d2f4b5d918d5e2601bd9de2 228 Hamap MF_01039 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [gpmA]. 1 228 43.278 T 28-03-2018 IPR005952 Phosphoglycerate mutase 1 GO:0004619|GO:0006096|GO:0016868 KEGG: 00010+5.4.2.11|KEGG: 00260+5.4.2.11|KEGG: 00680+5.4.2.11|MetaCyc: PWY-1622|MetaCyc: PWY-5484 CO689_RS04055 fe17a3980d2f4b5d918d5e2601bd9de2 228 PIRSF PIRSF000709 2 114 2.1E-6 T 28-03-2018 CO689_RS04055 fe17a3980d2f4b5d918d5e2601bd9de2 228 SMART SM00855 3 189 1.7E-24 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 CO689_RS04055 fe17a3980d2f4b5d918d5e2601bd9de2 228 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 4 131 1.4E-27 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 CO689_RS04055 fe17a3980d2f4b5d918d5e2601bd9de2 228 Gene3D G3DSA:3.40.50.1240 1 228 5.1E-56 T 28-03-2018 IPR029033 Histidine phosphatase superfamily CO689_RS00260 1504a218bdb8bbc83bade2cdbb1f6da7 203 Pfam PF00239 Resolvase, N terminal domain 2 145 1.2E-33 T 28-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CO689_RS00260 1504a218bdb8bbc83bade2cdbb1f6da7 203 Pfam PF02796 Helix-turn-helix domain of resolvase 147 199 2.6E-20 T 28-03-2018 IPR006120 Resolvase, HTH domain GO:0000150|GO:0003677|GO:0006310 CO689_RS00260 1504a218bdb8bbc83bade2cdbb1f6da7 203 Gene3D G3DSA:1.10.10.60 146 200 4.0E-15 T 28-03-2018 CO689_RS00260 1504a218bdb8bbc83bade2cdbb1f6da7 203 SMART SM00857 2 145 4.1E-42 T 28-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CO689_RS00260 1504a218bdb8bbc83bade2cdbb1f6da7 203 SUPERFAMILY SSF53041 1 145 9.16E-36 T 28-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CO689_RS00260 1504a218bdb8bbc83bade2cdbb1f6da7 203 ProSitePatterns PS00398 Site-specific recombinases signature 2. 56 68 - T 28-03-2018 IPR006118 Recombinase, conserved site GO:0000150|GO:0006310 CO689_RS00260 1504a218bdb8bbc83bade2cdbb1f6da7 203 ProSitePatterns PS00397 Site-specific recombinases active site. 5 13 - T 28-03-2018 IPR006118 Recombinase, conserved site GO:0000150|GO:0006310 CO689_RS00260 1504a218bdb8bbc83bade2cdbb1f6da7 203 Gene3D G3DSA:1.20.5.40 115 143 4.2E-9 T 28-03-2018 CO689_RS00260 1504a218bdb8bbc83bade2cdbb1f6da7 203 Gene3D G3DSA:3.40.50.1390 1 114 6.6E-31 T 28-03-2018 CO689_RS13110 c1145f1e2abd0566c602d1222a2c2c2e 324 Gene3D G3DSA:3.40.50.300 122 316 1.8E-24 T 28-03-2018 CO689_RS13110 c1145f1e2abd0566c602d1222a2c2c2e 324 SUPERFAMILY SSF52540 3 279 1.05E-47 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CO689_RS13110 c1145f1e2abd0566c602d1222a2c2c2e 324 Pfam PF00437 Type II/IV secretion system protein 8 266 1.2E-56 T 28-03-2018 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 CO689_RS13110 c1145f1e2abd0566c602d1222a2c2c2e 324 Gene3D G3DSA:3.30.450.90 1 104 2.8E-23 T 28-03-2018 CO689_RS02705 0f98889544861cd2bb3db1a5fcbd98a5 506 Pfam PF02378 Phosphotransferase system, EIIC 23 283 3.7E-16 T 28-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 CO689_RS02705 0f98889544861cd2bb3db1a5fcbd98a5 506 SUPERFAMILY SSF52794 413 503 3.66E-25 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 CO689_RS02705 0f98889544861cd2bb3db1a5fcbd98a5 506 Gene3D G3DSA:3.40.50.2300 401 506 7.6E-21 T 28-03-2018 CO689_RS02705 0f98889544861cd2bb3db1a5fcbd98a5 506 TIGRFAM TIGR00851 mtlA: PTS system, mannitol-specific IIC component 13 352 1.1E-183 T 28-03-2018 IPR004718 Phosphotransferase system, mannitol-specific enzyme IIC GO:0008982|GO:0009401|GO:0016021 KEGG: 00051+2.7.1.197|KEGG: 00710+2.7.1.19|MetaCyc: PWY-5723 CO689_RS02705 0f98889544861cd2bb3db1a5fcbd98a5 506 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 416 499 5.4E-11 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 CO689_RS01855 ae9db3a3b8ff0b560da1564cb6884e97 489 SUPERFAMILY SSF54675 6 138 3.39E-46 T 28-03-2018 CO689_RS01855 ae9db3a3b8ff0b560da1564cb6884e97 489 PIRSF PIRSF000484 3 479 2.6E-151 T 28-03-2018 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264 CO689_RS01855 ae9db3a3b8ff0b560da1564cb6884e97 489 Gene3D G3DSA:3.20.140.10 7 388 1.3E-126 T 28-03-2018 CO689_RS01855 ae9db3a3b8ff0b560da1564cb6884e97 489 Pfam PF04095 Nicotinate phosphoribosyltransferase (NAPRTase) family 155 335 2.2E-10 T 28-03-2018 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264 CO689_RS01855 ae9db3a3b8ff0b560da1564cb6884e97 489 SUPERFAMILY SSF51690 139 477 3.39E-128 T 28-03-2018 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 CO689_RS01855 ae9db3a3b8ff0b560da1564cb6884e97 489 TIGRFAM TIGR01513 NAPRTase_put: nicotinate phosphoribosyltransferase 11 464 5.7E-179 T 28-03-2018 IPR006405 Nicotinate phosphoribosyltransferase pncB-type GO:0004516|GO:0019358 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264|Reactome: R-HSA-6798695 CO689_RS02685 dc6408b5fcf3c3d22a7d647cb136e0f6 244 PIRSF PIRSF000883 1 240 8.9E-41 T 28-03-2018 IPR011152 Phosphoesterase MJ0912 CO689_RS02685 dc6408b5fcf3c3d22a7d647cb136e0f6 244 SUPERFAMILY SSF56300 1 234 5.91E-44 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CO689_RS02685 dc6408b5fcf3c3d22a7d647cb136e0f6 244 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 1 204 1.2E-23 T 28-03-2018 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 CO689_RS02685 dc6408b5fcf3c3d22a7d647cb136e0f6 244 Gene3D G3DSA:3.60.21.10 1 244 1.0E-30 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CO689_RS08305 77b16dcb4718bf53ae75c61364fa4990 358 SUPERFAMILY SSF55060 215 354 1.34E-30 T 28-03-2018 IPR013750 GHMP kinase, C-terminal domain CO689_RS08305 77b16dcb4718bf53ae75c61364fa4990 358 PRINTS PR00959 Mevalonate kinase family signature 313 330 1.9E-6 T 28-03-2018 CO689_RS08305 77b16dcb4718bf53ae75c61364fa4990 358 PRINTS PR00959 Mevalonate kinase family signature 112 134 1.9E-6 T 28-03-2018 CO689_RS08305 77b16dcb4718bf53ae75c61364fa4990 358 PRINTS PR00959 Mevalonate kinase family signature 6 30 1.9E-6 T 28-03-2018 CO689_RS08305 77b16dcb4718bf53ae75c61364fa4990 358 TIGRFAM TIGR01220 Pmev_kin_Gr_pos: phosphomevalonate kinase 2 358 1.0E-166 T 28-03-2018 IPR005917 Phosphomevalonate kinase KEGG: 00900+2.7.4.2|MetaCyc: PWY-7391|MetaCyc: PWY-922 CO689_RS08305 77b16dcb4718bf53ae75c61364fa4990 358 Gene3D G3DSA:3.30.230.10 1 220 8.3E-42 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CO689_RS08305 77b16dcb4718bf53ae75c61364fa4990 358 Pfam PF08544 GHMP kinases C terminal 262 345 9.7E-10 T 28-03-2018 IPR013750 GHMP kinase, C-terminal domain CO689_RS08305 77b16dcb4718bf53ae75c61364fa4990 358 Gene3D G3DSA:3.30.70.890 221 358 1.4E-24 T 28-03-2018 IPR013750 GHMP kinase, C-terminal domain CO689_RS08305 77b16dcb4718bf53ae75c61364fa4990 358 Pfam PF00288 GHMP kinases N terminal domain 104 174 2.7E-13 T 28-03-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 CO689_RS08305 77b16dcb4718bf53ae75c61364fa4990 358 SUPERFAMILY SSF54211 1 230 3.11E-44 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CO689_RS08760 0e0c022b61f233ea48de2c960ea3ccdb 309 Gene3D G3DSA:3.30.1220.10 206 308 1.8E-19 T 28-03-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal CO689_RS08760 0e0c022b61f233ea48de2c960ea3ccdb 309 Gene3D G3DSA:3.40.50.300 6 205 5.5E-35 T 28-03-2018 CO689_RS08760 0e0c022b61f233ea48de2c960ea3ccdb 309 SMART SM00833 221 307 1.0E-18 T 28-03-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal CO689_RS08760 0e0c022b61f233ea48de2c960ea3ccdb 309 Pfam PF07683 Cobalamin synthesis protein cobW C-terminal domain 221 306 1.1E-17 T 28-03-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal CO689_RS08760 0e0c022b61f233ea48de2c960ea3ccdb 309 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 11 188 3.2E-43 T 28-03-2018 IPR003495 CobW/HypB/UreG, nucleotide-binding domain CO689_RS08760 0e0c022b61f233ea48de2c960ea3ccdb 309 SUPERFAMILY SSF52540 8 265 4.07E-23 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CO689_RS04780 7c02e14aa1146693eec36cda989b02e5 343 TIGRFAM TIGR03175 AllD: ureidoglycolate dehydrogenase 9 343 3.2E-165 T 28-03-2018 IPR017590 Ureidoglycolate dehydrogenase KEGG: 00062+1.1.1.35|KEGG: 00071+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00230+1.1.1.350|KEGG: 00280+1.1.1.35|KEGG: 00281+1.1.1.35|KEGG: 00310+1.1.1.35|KEGG: 00362+1.1.1.35|KEGG: 00380+1.1.1.35|KEGG: 00623+1.1.1.35|KEGG: 00650+1.1.1.35|KEGG: 00720+1.1.1.35|KEGG: 00930+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5136|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 CO689_RS04780 7c02e14aa1146693eec36cda989b02e5 343 SUPERFAMILY SSF89733 7 339 3.66E-112 T 28-03-2018 IPR003767 Malate/L-lactate dehydrogenase-like GO:0008152|GO:0016491|GO:0055114 CO689_RS04780 7c02e14aa1146693eec36cda989b02e5 343 Pfam PF02615 Malate/L-lactate dehydrogenase 11 337 1.8E-115 T 28-03-2018 IPR003767 Malate/L-lactate dehydrogenase-like GO:0008152|GO:0016491|GO:0055114 CO689_RS04780 7c02e14aa1146693eec36cda989b02e5 343 Gene3D G3DSA:3.30.1370.60 86 311 7.2E-87 T 28-03-2018 CO689_RS04780 7c02e14aa1146693eec36cda989b02e5 343 Gene3D G3DSA:1.10.1530.10 9 85 1.3E-20 T 28-03-2018 CO689_RS12280 7fceca8d94abfc09e825f50feaeeaeb4 426 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 8 423 1.5E-146 T 28-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 CO689_RS12280 7fceca8d94abfc09e825f50feaeeaeb4 426 Gene3D G3DSA:3.40.640.10 5 290 1.1E-65 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CO689_RS12280 7fceca8d94abfc09e825f50feaeeaeb4 426 SUPERFAMILY SSF53383 6 423 8.11E-129 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CO689_RS12280 7fceca8d94abfc09e825f50feaeeaeb4 426 PIRSF PIRSF001434 1 426 5.5E-131 T 28-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 CO689_RS12280 7fceca8d94abfc09e825f50feaeeaeb4 426 TIGRFAM TIGR01326 OAH_OAS_sulfhy: O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase 6 423 1.2E-208 T 28-03-2018 IPR006235 O-acetylhomoserine/O-acetylserine sulfhydrylase GO:0006520|GO:0016765 CO689_RS12280 7fceca8d94abfc09e825f50feaeeaeb4 426 Gene3D G3DSA:3.90.1150.10 292 426 3.7E-48 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CO689_RS10075 a3ca36704dc057e64ca00922a0ada8ca 400 Pfam PF00764 Arginosuccinate synthase 6 389 2.2E-170 T 28-03-2018 IPR001518 Argininosuccinate synthase GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CO689_RS10075 a3ca36704dc057e64ca00922a0ada8ca 400 SUPERFAMILY SSF69864 169 394 1.22E-92 T 28-03-2018 CO689_RS10075 a3ca36704dc057e64ca00922a0ada8ca 400 Hamap MF_00005 Argininosuccinate synthase [argG]. 2 395 53.407 T 28-03-2018 IPR023434 Argininosuccinate synthase, type 1 subfamily GO:0004055 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CO689_RS10075 a3ca36704dc057e64ca00922a0ada8ca 400 Gene3D G3DSA:3.40.50.620 3 156 9.1E-26 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CO689_RS10075 a3ca36704dc057e64ca00922a0ada8ca 400 TIGRFAM TIGR00032 argG: argininosuccinate synthase 4 391 5.4E-161 T 28-03-2018 IPR001518 Argininosuccinate synthase GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CO689_RS10075 a3ca36704dc057e64ca00922a0ada8ca 400 SUPERFAMILY SSF52402 2 164 1.19E-45 T 28-03-2018 CO689_RS10075 a3ca36704dc057e64ca00922a0ada8ca 400 ProSitePatterns PS00564 Argininosuccinate synthase signature 1. 8 16 - T 28-03-2018 IPR018223 Argininosuccinate synthase, conserved site GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CO689_RS10075 a3ca36704dc057e64ca00922a0ada8ca 400 ProSitePatterns PS00565 Argininosuccinate synthase signature 2. 115 126 - T 28-03-2018 IPR018223 Argininosuccinate synthase, conserved site GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CO689_RS10075 a3ca36704dc057e64ca00922a0ada8ca 400 Gene3D G3DSA:1.20.5.470 361 394 6.5E-10 T 28-03-2018 CO689_RS10075 a3ca36704dc057e64ca00922a0ada8ca 400 Gene3D G3DSA:3.90.1260.10 157 351 5.1E-85 T 28-03-2018 IPR024074 Argininosuccinate synthetase, catalytic/multimerisation domain body GO:0004055 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CO689_RS04975 4c6a290acfbcb193be4659661a596bac 455 SUPERFAMILY SSF55424 325 444 2.23E-29 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CO689_RS04975 4c6a290acfbcb193be4659661a596bac 455 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 2 24 1.8E-13 T 28-03-2018 CO689_RS04975 4c6a290acfbcb193be4659661a596bac 455 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 276 283 1.8E-13 T 28-03-2018 CO689_RS04975 4c6a290acfbcb193be4659661a596bac 455 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 149 174 1.8E-13 T 28-03-2018 CO689_RS04975 4c6a290acfbcb193be4659661a596bac 455 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 236 250 1.8E-13 T 28-03-2018 CO689_RS04975 4c6a290acfbcb193be4659661a596bac 455 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 103 121 1.0E-18 T 28-03-2018 CO689_RS04975 4c6a290acfbcb193be4659661a596bac 455 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 3 22 1.0E-18 T 28-03-2018 CO689_RS04975 4c6a290acfbcb193be4659661a596bac 455 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 149 167 1.0E-18 T 28-03-2018 CO689_RS04975 4c6a290acfbcb193be4659661a596bac 455 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 261 283 1.0E-18 T 28-03-2018 CO689_RS04975 4c6a290acfbcb193be4659661a596bac 455 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 235 251 1.0E-18 T 28-03-2018 CO689_RS04975 4c6a290acfbcb193be4659661a596bac 455 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 2 306 1.5E-52 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CO689_RS04975 4c6a290acfbcb193be4659661a596bac 455 Gene3D G3DSA:3.50.50.60 245 324 1.4E-7 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CO689_RS04975 4c6a290acfbcb193be4659661a596bac 455 SUPERFAMILY SSF51905 1 316 2.53E-40 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CO689_RS04975 4c6a290acfbcb193be4659661a596bac 455 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 331 429 3.1E-9 T 28-03-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 CO689_RS04975 4c6a290acfbcb193be4659661a596bac 455 Gene3D G3DSA:3.30.390.30 325 446 2.6E-16 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CO689_RS04975 4c6a290acfbcb193be4659661a596bac 455 Gene3D G3DSA:3.50.50.60 103 244 4.3E-29 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CO689_RS04975 4c6a290acfbcb193be4659661a596bac 455 Gene3D G3DSA:3.50.50.60 6 102 1.9E-11 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CO689_RS10515 c33a9efb77545c23620112df4af20594 312 Pfam PF01040 UbiA prenyltransferase family 27 277 1.7E-35 T 28-03-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 CO689_RS10515 c33a9efb77545c23620112df4af20594 312 PIRSF PIRSF005355 2 308 1.1E-77 T 28-03-2018 IPR026046 UbiA prenyltransferase domain containing protein 1 GO:0004659 Reactome: R-HSA-6806664 CO689_RS10515 c33a9efb77545c23620112df4af20594 312 Hamap MF_01937 1,4-dihydroxy-2-naphthoate octaprenyltransferase [menA]. 10 303 18.765 T 28-03-2018 IPR004657 1,4-dihydroxy-2-naphthoate octaprenyltransferase GO:0009234|GO:0016021|GO:0046428 KEGG: 00130+2.5.1.74|MetaCyc: PWY-5839|MetaCyc: PWY-5851|MetaCyc: PWY-5852|MetaCyc: PWY-5853|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895 CO689_RS10515 c33a9efb77545c23620112df4af20594 312 TIGRFAM TIGR00751 menA: 1,4-dihydroxy-2-naphthoate octaprenyltransferase 19 302 6.0E-32 T 28-03-2018 CO689_RS11680 70d8c9a664cc3b070e79743632d9a70c 293 ProSitePatterns PS01126 Elongation factor Ts signature 1. 12 27 - T 28-03-2018 IPR018101 Translation elongation factor Ts, conserved site GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CO689_RS11680 70d8c9a664cc3b070e79743632d9a70c 293 SUPERFAMILY SSF54713 152 293 1.28E-49 T 28-03-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CO689_RS11680 70d8c9a664cc3b070e79743632d9a70c 293 Pfam PF00889 Elongation factor TS 71 275 4.3E-75 T 28-03-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CO689_RS11680 70d8c9a664cc3b070e79743632d9a70c 293 SUPERFAMILY SSF46934 3 56 3.23E-21 T 28-03-2018 IPR009060 UBA-like GO:0005515 CO689_RS11680 70d8c9a664cc3b070e79743632d9a70c 293 TIGRFAM TIGR00116 tsf: translation elongation factor Ts 1 293 1.1E-115 T 28-03-2018 IPR001816 Translation elongation factor EFTs/EF1B GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CO689_RS11680 70d8c9a664cc3b070e79743632d9a70c 293 ProSitePatterns PS01127 Elongation factor Ts signature 2. 75 85 - T 28-03-2018 IPR018101 Translation elongation factor Ts, conserved site GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CO689_RS11680 70d8c9a664cc3b070e79743632d9a70c 293 Gene3D G3DSA:3.30.479.20 58 158 2.3E-22 T 28-03-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CO689_RS11680 70d8c9a664cc3b070e79743632d9a70c 293 Gene3D G3DSA:1.10.8.10 1 56 1.5E-27 T 28-03-2018 CO689_RS11680 70d8c9a664cc3b070e79743632d9a70c 293 Gene3D G3DSA:3.30.479.20 159 291 5.3E-49 T 28-03-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CO689_RS11680 70d8c9a664cc3b070e79743632d9a70c 293 SUPERFAMILY SSF54713 56 144 2.62E-21 T 28-03-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CO689_RS11680 70d8c9a664cc3b070e79743632d9a70c 293 Hamap MF_00050 Elongation factor Ts [tsf]. 1 292 80.952 T 28-03-2018 IPR001816 Translation elongation factor EFTs/EF1B GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CO689_RS12335 bfae8f98f2e819f5cfe3f9fea9efd76b 338 Gene3D G3DSA:1.20.970.10 1 82 0.11 T 28-03-2018 CO689_RS12335 bfae8f98f2e819f5cfe3f9fea9efd76b 338 TIGRFAM TIGR01245 trpD: anthranilate phosphoribosyltransferase 4 328 8.5E-98 T 28-03-2018 IPR005940 Anthranilate phosphoribosyl transferase GO:0000162|GO:0004048 KEGG: 00400+2.4.2.18 CO689_RS12335 bfae8f98f2e819f5cfe3f9fea9efd76b 338 SUPERFAMILY SSF52418 71 328 6.8E-79 T 28-03-2018 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CO689_RS12335 bfae8f98f2e819f5cfe3f9fea9efd76b 338 Gene3D G3DSA:3.40.1030.10 83 329 3.7E-85 T 28-03-2018 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CO689_RS12335 bfae8f98f2e819f5cfe3f9fea9efd76b 338 Pfam PF00591 Glycosyl transferase family, a/b domain 76 322 1.7E-83 T 28-03-2018 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CO689_RS12335 bfae8f98f2e819f5cfe3f9fea9efd76b 338 SUPERFAMILY SSF47648 2 66 1.24E-5 T 28-03-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 CO689_RS12335 bfae8f98f2e819f5cfe3f9fea9efd76b 338 Hamap MF_00211 Anthranilate phosphoribosyltransferase [trpD]. 2 332 33.37 T 28-03-2018 IPR005940 Anthranilate phosphoribosyl transferase GO:0000162|GO:0004048 KEGG: 00400+2.4.2.18 CO689_RS09480 9aaadd363b1b5b77c6ea8dfc699a1d4c 275 Gene3D G3DSA:3.40.190.10 31 128 8.7E-27 T 28-03-2018 CO689_RS09480 9aaadd363b1b5b77c6ea8dfc699a1d4c 275 SUPERFAMILY SSF53850 34 274 3.47E-77 T 28-03-2018 CO689_RS09480 9aaadd363b1b5b77c6ea8dfc699a1d4c 275 Gene3D G3DSA:3.40.190.10 129 274 1.2E-42 T 28-03-2018 CO689_RS09480 9aaadd363b1b5b77c6ea8dfc699a1d4c 275 Pfam PF03180 NLPA lipoprotein 35 274 1.3E-85 T 28-03-2018 IPR004872 Lipoprotein NlpA family CO689_RS09480 9aaadd363b1b5b77c6ea8dfc699a1d4c 275 PIRSF PIRSF002854 1 275 1.3E-96 T 28-03-2018 IPR004872 Lipoprotein NlpA family CO689_RS12735 cb696acbb5ad11fd6f0ae998327ccb75 376 Gene3D G3DSA:3.40.50.2000 186 354 2.0E-38 T 28-03-2018 CO689_RS12735 cb696acbb5ad11fd6f0ae998327ccb75 376 Pfam PF00534 Glycosyl transferases group 1 184 345 1.0E-36 T 28-03-2018 IPR001296 Glycosyl transferase, family 1 CO689_RS12735 cb696acbb5ad11fd6f0ae998327ccb75 376 Gene3D G3DSA:3.40.50.2000 1 185 1.0E-11 T 28-03-2018 CO689_RS12735 cb696acbb5ad11fd6f0ae998327ccb75 376 SUPERFAMILY SSF53756 6 373 8.37E-76 T 28-03-2018 CO689_RS12735 cb696acbb5ad11fd6f0ae998327ccb75 376 TIGRFAM TIGR03999 thiol_BshA: N-acetyl-alpha-D-glucosaminyl L-malate synthase BshA 1 371 5.9E-162 T 28-03-2018 IPR023881 N-acetyl-alpha-D-glucosaminyl L-malate synthase BshA GO:0016757|GO:0071793 CO689_RS12735 cb696acbb5ad11fd6f0ae998327ccb75 376 Pfam PF13439 Glycosyltransferase Family 4 11 173 1.4E-19 T 28-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 CO689_RS13355 a917705dba42a123a7e5f66c91b9a3db 116 TIGRFAM TIGR00090 rsfS_iojap_ybeB: ribosome silencing factor 8 104 3.5E-31 T 28-03-2018 IPR004394 Protein Iojap/ribosomal silencing factor RsfS CO689_RS13355 a917705dba42a123a7e5f66c91b9a3db 116 Gene3D G3DSA:3.30.460.10 1 115 1.7E-27 T 28-03-2018 CO689_RS13355 a917705dba42a123a7e5f66c91b9a3db 116 SUPERFAMILY SSF81301 1 113 3.11E-34 T 28-03-2018 CO689_RS13355 a917705dba42a123a7e5f66c91b9a3db 116 Hamap MF_01477 Ribosomal silencing factor RsfS [rsfS]. 3 105 21.531 T 28-03-2018 IPR004394 Protein Iojap/ribosomal silencing factor RsfS CO689_RS13355 a917705dba42a123a7e5f66c91b9a3db 116 Pfam PF02410 Ribosomal silencing factor during starvation 11 104 2.4E-22 T 28-03-2018 CO689_RS07125 18fef5841c8062c678d01606e965ae7c 334 Hamap MF_01109 Ornithine carbamoyltransferase, catabolic [argI]. 6 331 81.759 T 28-03-2018 IPR024904 Ornithine carbamoyltransferase GO:0004585|GO:0006591 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400 CO689_RS07125 18fef5841c8062c678d01606e965ae7c 334 Gene3D G3DSA:3.40.50.1370 165 332 7.1E-50 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CO689_RS07125 18fef5841c8062c678d01606e965ae7c 334 TIGRFAM TIGR00658 orni_carb_tr: ornithine carbamoyltransferase 7 330 1.0E-125 T 28-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CO689_RS07125 18fef5841c8062c678d01606e965ae7c 334 PRINTS PR00102 Ornithine carbamoyltransferase signature 50 64 5.7E-30 T 28-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CO689_RS07125 18fef5841c8062c678d01606e965ae7c 334 PRINTS PR00102 Ornithine carbamoyltransferase signature 228 238 5.7E-30 T 28-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CO689_RS07125 18fef5841c8062c678d01606e965ae7c 334 PRINTS PR00102 Ornithine carbamoyltransferase signature 83 96 5.7E-30 T 28-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CO689_RS07125 18fef5841c8062c678d01606e965ae7c 334 PRINTS PR00102 Ornithine carbamoyltransferase signature 123 137 5.7E-30 T 28-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CO689_RS07125 18fef5841c8062c678d01606e965ae7c 334 PRINTS PR00102 Ornithine carbamoyltransferase signature 309 320 5.7E-30 T 28-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CO689_RS07125 18fef5841c8062c678d01606e965ae7c 334 SUPERFAMILY SSF53671 1 332 4.45E-100 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CO689_RS07125 18fef5841c8062c678d01606e965ae7c 334 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 7 147 7.3E-46 T 28-03-2018 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 CO689_RS07125 18fef5841c8062c678d01606e965ae7c 334 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 155 328 9.3E-56 T 28-03-2018 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 CO689_RS07125 18fef5841c8062c678d01606e965ae7c 334 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 52 59 - T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CO689_RS07125 18fef5841c8062c678d01606e965ae7c 334 Gene3D G3DSA:3.40.50.1370 5 164 3.5E-54 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CO689_RS07125 18fef5841c8062c678d01606e965ae7c 334 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 134 145 2.1E-24 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CO689_RS07125 18fef5841c8062c678d01606e965ae7c 334 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 266 275 2.1E-24 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CO689_RS07125 18fef5841c8062c678d01606e965ae7c 334 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 52 71 2.1E-24 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CO689_RS07125 18fef5841c8062c678d01606e965ae7c 334 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 295 318 2.1E-24 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CO689_RS01400 80c19b660049a9abb9b9e4a75e4653be 208 ProSitePatterns PS00622 LuxR-type HTH domain signature. 162 189 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CO689_RS01400 80c19b660049a9abb9b9e4a75e4653be 208 SMART SM00448 2 117 3.4E-27 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CO689_RS01400 80c19b660049a9abb9b9e4a75e4653be 208 Pfam PF00196 Bacterial regulatory proteins, luxR family 147 202 1.9E-21 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CO689_RS01400 80c19b660049a9abb9b9e4a75e4653be 208 SMART SM00421 145 202 3.2E-25 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CO689_RS01400 80c19b660049a9abb9b9e4a75e4653be 208 SUPERFAMILY SSF52172 2 134 1.57E-31 T 28-03-2018 IPR011006 CheY-like superfamily CO689_RS01400 80c19b660049a9abb9b9e4a75e4653be 208 SUPERFAMILY SSF46894 134 208 1.84E-22 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CO689_RS01400 80c19b660049a9abb9b9e4a75e4653be 208 Gene3D G3DSA:3.40.50.2300 2 128 2.9E-30 T 28-03-2018 CO689_RS01400 80c19b660049a9abb9b9e4a75e4653be 208 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 178 190 8.1E-15 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CO689_RS01400 80c19b660049a9abb9b9e4a75e4653be 208 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 162 178 8.1E-15 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CO689_RS01400 80c19b660049a9abb9b9e4a75e4653be 208 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 148 162 8.1E-15 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CO689_RS01400 80c19b660049a9abb9b9e4a75e4653be 208 Gene3D G3DSA:1.10.10.10 129 208 8.1E-29 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS01400 80c19b660049a9abb9b9e4a75e4653be 208 Pfam PF00072 Response regulator receiver domain 4 117 2.8E-24 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CO689_RS07685 d3d167d8bfc3e69826e84d2a92413c7a 296 Gene3D G3DSA:1.10.8.100 227 290 4.1E-22 T 28-03-2018 IPR023165 rRNA adenine dimethylase-like Reactome: R-HSA-2151201|Reactome: R-HSA-6793080 CO689_RS07685 d3d167d8bfc3e69826e84d2a92413c7a 296 SMART SM00650 37 213 1.8E-79 T 28-03-2018 IPR020598 Ribosomal RNA adenine methylase transferase, N-terminal GO:0000154|GO:0000179|GO:0008649 CO689_RS07685 d3d167d8bfc3e69826e84d2a92413c7a 296 SUPERFAMILY SSF53335 20 291 4.38E-72 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CO689_RS07685 d3d167d8bfc3e69826e84d2a92413c7a 296 Gene3D G3DSA:3.40.50.150 3 226 3.0E-55 T 28-03-2018 CO689_RS07685 d3d167d8bfc3e69826e84d2a92413c7a 296 TIGRFAM TIGR00755 ksgA: ribosomal RNA small subunit methyltransferase A 21 287 6.2E-83 T 28-03-2018 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 CO689_RS07685 d3d167d8bfc3e69826e84d2a92413c7a 296 Pfam PF00398 Ribosomal RNA adenine dimethylase 21 280 9.4E-71 T 28-03-2018 IPR001737 Ribosomal RNA adenine methyltransferase KsgA/Erm CO689_RS07685 d3d167d8bfc3e69826e84d2a92413c7a 296 ProSitePatterns PS01131 Ribosomal RNA adenine dimethylases signature. 53 80 - T 28-03-2018 IPR020596 Ribosomal RNA adenine methylase transferase, conserved site GO:0000154|GO:0000179|GO:0008649 CO689_RS07685 d3d167d8bfc3e69826e84d2a92413c7a 296 Hamap MF_00607 Ribosomal RNA small subunit methyltransferase A [rsmA]. 21 289 53.313 T 28-03-2018 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 CO689_RS02825 d0e74cf373384ed13713d6f48afe8c3c 363 Pfam PF06772 Bacterial low temperature requirement A protein (LtrA) 6 347 4.4E-43 T 28-03-2018 IPR010640 Low temperature requirement A CO689_RS02180 b58c18a1737eafb44e007ae4375f9c0e 564 Hamap MF_00012 Dihydroxy-acid dehydratase [ilvD]. 1 556 46.303 T 28-03-2018 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 CO689_RS02180 b58c18a1737eafb44e007ae4375f9c0e 564 Pfam PF00920 Dehydratase family 33 552 3.7E-225 T 28-03-2018 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 CO689_RS02180 b58c18a1737eafb44e007ae4375f9c0e 564 SUPERFAMILY SSF143975 2 375 4.05E-136 T 28-03-2018 CO689_RS02180 b58c18a1737eafb44e007ae4375f9c0e 564 SUPERFAMILY SSF52016 376 557 1.88E-62 T 28-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel CO689_RS02180 b58c18a1737eafb44e007ae4375f9c0e 564 TIGRFAM TIGR00110 ilvD: dihydroxy-acid dehydratase 14 556 1.6E-242 T 28-03-2018 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 CO689_RS02180 b58c18a1737eafb44e007ae4375f9c0e 564 Gene3D G3DSA:3.40.50.2300 36 258 2.7E-5 T 28-03-2018 CO689_RS02180 b58c18a1737eafb44e007ae4375f9c0e 564 ProSitePatterns PS00886 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 1. 121 131 - T 28-03-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 CO689_RS02180 b58c18a1737eafb44e007ae4375f9c0e 564 ProSitePatterns PS00887 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 2. 464 475 - T 28-03-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 CO689_RS07240 48bc5b32502905a993d1b9f8499ff442 422 TIGRFAM TIGR00801 ncs2: uracil-xanthine permease 2 407 2.9E-126 T 28-03-2018 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 CO689_RS07240 48bc5b32502905a993d1b9f8499ff442 422 Pfam PF00860 Permease family 2 378 3.4E-108 T 28-03-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 CO689_RS07240 48bc5b32502905a993d1b9f8499ff442 422 TIGRFAM TIGR03173 pbuX: xanthine permease 6 410 1.4E-153 T 28-03-2018 IPR017588 Uric acid permease UacT-like GO:0006810|GO:0016021 CO689_RS07240 48bc5b32502905a993d1b9f8499ff442 422 ProSitePatterns PS01116 Xanthine/uracil permeases family signature. 325 345 - T 28-03-2018 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 CO689_RS02710 786b34e82c3b2e13f6059c0d6fdfb56e 676 Gene3D G3DSA:1.10.1790.10 163 296 1.4E-14 T 28-03-2018 IPR011608 PRD domain GO:0006355 CO689_RS02710 786b34e82c3b2e13f6059c0d6fdfb56e 676 Gene3D G3DSA:1.10.1790.10 297 405 1.5E-16 T 28-03-2018 IPR011608 PRD domain GO:0006355 CO689_RS02710 786b34e82c3b2e13f6059c0d6fdfb56e 676 Pfam PF00874 PRD domain 209 293 6.1E-13 T 28-03-2018 IPR011608 PRD domain GO:0006355 CO689_RS02710 786b34e82c3b2e13f6059c0d6fdfb56e 676 Pfam PF00874 PRD domain 314 401 1.0E-18 T 28-03-2018 IPR011608 PRD domain GO:0006355 CO689_RS02710 786b34e82c3b2e13f6059c0d6fdfb56e 676 SUPERFAMILY SSF63520 311 404 9.42E-18 T 28-03-2018 IPR011608 PRD domain GO:0006355 CO689_RS02710 786b34e82c3b2e13f6059c0d6fdfb56e 676 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 530 662 7.9E-7 T 28-03-2018 IPR002178 PTS EIIA type-2 domain CO689_RS02710 786b34e82c3b2e13f6059c0d6fdfb56e 676 SUPERFAMILY SSF55804 536 641 6.54E-7 T 28-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 CO689_RS02710 786b34e82c3b2e13f6059c0d6fdfb56e 676 SUPERFAMILY SSF46785 83 134 4.93E-5 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS02710 786b34e82c3b2e13f6059c0d6fdfb56e 676 Pfam PF08279 HTH domain 6 65 1.2E-11 T 28-03-2018 IPR013196 Helix-turn-helix, type 11 CO689_RS02710 786b34e82c3b2e13f6059c0d6fdfb56e 676 SUPERFAMILY SSF46785 1 58 1.95E-6 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS02710 786b34e82c3b2e13f6059c0d6fdfb56e 676 Gene3D G3DSA:3.40.50.2300 409 496 6.2E-17 T 28-03-2018 CO689_RS02710 786b34e82c3b2e13f6059c0d6fdfb56e 676 Gene3D G3DSA:1.10.10.10 1 69 6.5E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS02710 786b34e82c3b2e13f6059c0d6fdfb56e 676 Gene3D G3DSA:1.10.10.10 87 154 1.7E-7 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS02710 786b34e82c3b2e13f6059c0d6fdfb56e 676 SUPERFAMILY SSF63520 191 297 2.49E-17 T 28-03-2018 IPR011608 PRD domain GO:0006355 CO689_RS02710 786b34e82c3b2e13f6059c0d6fdfb56e 676 SUPERFAMILY SSF52794 411 499 2.14E-9 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 CO689_RS02710 786b34e82c3b2e13f6059c0d6fdfb56e 676 Gene3D G3DSA:3.40.930.10 528 664 2.7E-6 T 28-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 CO689_RS04770 2fc14acdd1bfe8861c6043aa41133a22 583 Pfam PF00549 CoA-ligase 340 494 1.8E-52 T 28-03-2018 IPR005811 ATP-citrate lyase/succinyl-CoA ligase GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CO689_RS04770 2fc14acdd1bfe8861c6043aa41133a22 583 SUPERFAMILY SSF52210 183 312 2.09E-18 T 28-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CO689_RS04770 2fc14acdd1bfe8861c6043aa41133a22 583 SUPERFAMILY SSF52210 343 497 3.66E-10 T 28-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CO689_RS04770 2fc14acdd1bfe8861c6043aa41133a22 583 Gene3D G3DSA:3.40.50.261 168 515 1.6E-34 T 28-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CO689_RS04770 2fc14acdd1bfe8861c6043aa41133a22 583 Gene3D G3DSA:3.40.50.720 59 167 1.9E-7 T 28-03-2018 CO689_RS04770 2fc14acdd1bfe8861c6043aa41133a22 583 Pfam PF02629 CoA binding domain 189 283 2.7E-13 T 28-03-2018 IPR003781 CoA-binding GO:0048037 CO689_RS02015 d7b27e565c6833aa3ef4642b221e0f90 410 Pfam PF05065 Phage capsid family 138 400 6.7E-34 T 28-03-2018 IPR024455 Phage capsid CO689_RS02015 d7b27e565c6833aa3ef4642b221e0f90 410 Gene3D G3DSA:3.30.2400.10 158 296 1.1E-17 T 28-03-2018 CO689_RS02015 d7b27e565c6833aa3ef4642b221e0f90 410 SUPERFAMILY SSF56563 131 401 1.57E-38 T 28-03-2018 CO689_RS02015 d7b27e565c6833aa3ef4642b221e0f90 410 TIGRFAM TIGR01554 major_cap_HK97: phage major capsid protein, HK97 family 18 400 5.9E-48 T 28-03-2018 IPR024455 Phage capsid CO689_RS11415 9f1c095111a82102bce619dc555793c2 802 Gene3D G3DSA:3.40.50.300 265 430 3.2E-25 T 28-03-2018 CO689_RS11415 9f1c095111a82102bce619dc555793c2 802 SMART SM00490 563 660 3.4E-12 T 28-03-2018 IPR001650 Helicase, C-terminal CO689_RS11415 9f1c095111a82102bce619dc555793c2 802 Hamap MF_00983 Probable primosomal protein N' [priA]. 8 801 25.107 T 28-03-2018 IPR005259 Primosomal protein N' GO:0003677|GO:0004003|GO:0006260|GO:0032508 CO689_RS11415 9f1c095111a82102bce619dc555793c2 802 SUPERFAMILY SSF52540 529 706 4.53E-33 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CO689_RS11415 9f1c095111a82102bce619dc555793c2 802 Gene3D G3DSA:3.40.50.300 462 691 1.9E-23 T 28-03-2018 CO689_RS11415 9f1c095111a82102bce619dc555793c2 802 SUPERFAMILY SSF52540 262 445 3.61E-41 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CO689_RS11415 9f1c095111a82102bce619dc555793c2 802 TIGRFAM TIGR00595 priA: primosomal protein N' 289 799 5.2E-213 T 28-03-2018 IPR005259 Primosomal protein N' GO:0003677|GO:0004003|GO:0006260|GO:0032508 CO689_RS11415 9f1c095111a82102bce619dc555793c2 802 Pfam PF00271 Helicase conserved C-terminal domain 563 659 1.6E-8 T 28-03-2018 IPR001650 Helicase, C-terminal CO689_RS11415 9f1c095111a82102bce619dc555793c2 802 SMART SM00487 261 460 5.4E-22 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CO689_RS11415 9f1c095111a82102bce619dc555793c2 802 Pfam PF04851 Type III restriction enzyme, res subunit 264 428 5.1E-18 T 28-03-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 CO689_RS05225 2f4b2f209f5f924d49843fdf568451bd 873 ProSitePatterns PS00913 Iron-containing alcohol dehydrogenases signature 1. 644 672 - T 28-03-2018 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 CO689_RS05225 2f4b2f209f5f924d49843fdf568451bd 873 Gene3D G3DSA:1.20.1090.10 656 873 1.4E-61 T 28-03-2018 CO689_RS05225 2f4b2f209f5f924d49843fdf568451bd 873 PIRSF PIRSF000111 7 873 0.0 T 28-03-2018 IPR012079 Bifunctional aldehyde-alcohol dehydrogenase GO:0004022|GO:0006066|GO:0008774|GO:0015976|GO:0055114 KEGG: 00010+1.1.1.1|KEGG: 00071+1.1.1.1|KEGG: 00260+1.1.1.1|KEGG: 00350+1.1.1.1|KEGG: 00592+1.1.1.1|KEGG: 00625+1.1.1.1|KEGG: 00626+1.1.1.1|KEGG: 00830+1.1.1.1|KEGG: 00980+1.1.1.1|KEGG: 00982+1.1.1.1|MetaCyc: PWY-3162|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5079|MetaCyc: PWY-5082|MetaCyc: PWY-5480|MetaCyc: PWY-5486|MetaCyc: PWY-5751|MetaCyc: PWY-6313|MetaCyc: PWY-6333|MetaCyc: PWY-6342|MetaCyc: PWY-6587|MetaCyc: PWY-6802|MetaCyc: PWY-6871|MetaCyc: PWY-7013|MetaCyc: PWY-7111|MetaCyc: PWY-7118|MetaCyc: PWY-7396 CO689_RS05225 2f4b2f209f5f924d49843fdf568451bd 873 Gene3D G3DSA:3.40.605.10 3 247 1.1E-30 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CO689_RS05225 2f4b2f209f5f924d49843fdf568451bd 873 Gene3D G3DSA:3.40.309.10 248 419 1.6E-27 T 28-03-2018 CO689_RS05225 2f4b2f209f5f924d49843fdf568451bd 873 SUPERFAMILY SSF56796 462 869 3.4E-116 T 28-03-2018 CO689_RS05225 2f4b2f209f5f924d49843fdf568451bd 873 Pfam PF00171 Aldehyde dehydrogenase family 21 416 5.0E-28 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CO689_RS05225 2f4b2f209f5f924d49843fdf568451bd 873 ProSitePatterns PS00060 Iron-containing alcohol dehydrogenases signature 2. 730 750 - T 28-03-2018 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 CO689_RS05225 2f4b2f209f5f924d49843fdf568451bd 873 Gene3D G3DSA:3.40.50.1970 444 655 1.0E-51 T 28-03-2018 CO689_RS05225 2f4b2f209f5f924d49843fdf568451bd 873 Pfam PF00465 Iron-containing alcohol dehydrogenase 471 858 2.8E-115 T 28-03-2018 IPR001670 Alcohol dehydrogenase, iron-type GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 CO689_RS05225 2f4b2f209f5f924d49843fdf568451bd 873 SUPERFAMILY SSF53720 22 467 1.09E-83 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CO689_RS11195 d27823958d7a659a3af3fa630bdc41f0 537 Pfam PF10079 Bacillithiol biosynthesis BshC 1 528 3.1E-157 T 28-03-2018 IPR011199 Bacillithiol biosynthesis BshC CO689_RS11195 d27823958d7a659a3af3fa630bdc41f0 537 TIGRFAM TIGR03998 thiol_BshC: bacillithiol biosynthesis cysteine-adding enzyme BshC 12 535 2.6E-172 T 28-03-2018 IPR011199 Bacillithiol biosynthesis BshC CO689_RS11195 d27823958d7a659a3af3fa630bdc41f0 537 Hamap MF_01867 Putative cysteine ligase BshC [bshC]. 1 537 29.916 T 28-03-2018 IPR011199 Bacillithiol biosynthesis BshC CO689_RS11195 d27823958d7a659a3af3fa630bdc41f0 537 PIRSF PIRSF012535 1 537 5.1E-203 T 28-03-2018 IPR011199 Bacillithiol biosynthesis BshC CO689_RS02515 500deed1fa3479dcbe2bb4efe0370f8c 279 Hamap MF_02126 Release factor glutamine methyltransferase [prmC]. 3 277 35.938 T 28-03-2018 IPR019874 Protein-(glutamine-N5) methyltransferase, release factor-specific GO:0008168 CO689_RS02515 500deed1fa3479dcbe2bb4efe0370f8c 279 SUPERFAMILY SSF53335 20 253 9.95E-39 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CO689_RS02515 500deed1fa3479dcbe2bb4efe0370f8c 279 Gene3D G3DSA:1.10.8.10 1 79 9.4E-17 T 28-03-2018 CO689_RS02515 500deed1fa3479dcbe2bb4efe0370f8c 279 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 180 186 - T 28-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 CO689_RS02515 500deed1fa3479dcbe2bb4efe0370f8c 279 Gene3D G3DSA:3.40.50.150 80 279 1.3E-32 T 28-03-2018 CO689_RS02515 500deed1fa3479dcbe2bb4efe0370f8c 279 TIGRFAM TIGR03534 RF_mod_PrmC: protein-(glutamine-N5) methyltransferase, release factor-specific 24 273 9.3E-73 T 28-03-2018 IPR019874 Protein-(glutamine-N5) methyltransferase, release factor-specific GO:0008168 CO689_RS02515 500deed1fa3479dcbe2bb4efe0370f8c 279 Pfam PF05175 Methyltransferase small domain 102 197 3.2E-10 T 28-03-2018 IPR007848 Methyltransferase small domain GO:0008168 CO689_RS02515 500deed1fa3479dcbe2bb4efe0370f8c 279 TIGRFAM TIGR00536 hemK_fam: methyltransferase, HemK family 5 276 5.8E-59 T 28-03-2018 IPR004556 Modification methylase HemK GO:0006479|GO:0008276 CO689_RS02785 4a94fac70332d967c606809396c9d080 357 Gene3D G3DSA:3.40.50.300 96 324 2.2E-53 T 28-03-2018 CO689_RS02785 4a94fac70332d967c606809396c9d080 357 Gene3D G3DSA:3.30.300.130 2 92 4.6E-5 T 28-03-2018 IPR034904 Fe-S cluster assembly domain CO689_RS02785 4a94fac70332d967c606809396c9d080 357 SUPERFAMILY SSF52540 114 353 3.75E-47 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CO689_RS02785 4a94fac70332d967c606809396c9d080 357 Hamap MF_02040 Iron-sulfur cluster carrier protein. 103 351 34.058 T 28-03-2018 IPR019591 Mrp/NBP35 ATP-binding protein CO689_RS02785 4a94fac70332d967c606809396c9d080 357 ProSitePatterns PS01215 Mrp family signature. 216 232 - T 28-03-2018 IPR000808 Mrp, conserved site GO:0005524 CO689_RS02785 4a94fac70332d967c606809396c9d080 357 Pfam PF10609 NUBPL iron-transfer P-loop NTPase 114 350 3.7E-88 T 28-03-2018 IPR033756 Flagellum site-determining protein YlxH/ Fe-S cluster assembling factor NBP35 CO689_RS01300 f0513f46a558f374eda673fd248d3599 277 SUPERFAMILY SSF54675 3 108 1.57E-25 T 28-03-2018 CO689_RS01300 f0513f46a558f374eda673fd248d3599 277 PIRSF PIRSF006250 4 277 2.1E-81 T 28-03-2018 IPR027277 Nicotinate-nucleotide pyrophosphorylase/Putative pyrophosphorylase ModD Reactome: R-HSA-196807 CO689_RS01300 f0513f46a558f374eda673fd248d3599 277 Gene3D G3DSA:3.20.20.70 130 265 5.3E-35 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CO689_RS01300 f0513f46a558f374eda673fd248d3599 277 Gene3D G3DSA:3.90.1170.20 1 129 5.5E-36 T 28-03-2018 IPR022412 Quinolinate phosphoribosyl transferase, N-terminal GO:0016763 Reactome: R-HSA-196807 CO689_RS01300 f0513f46a558f374eda673fd248d3599 277 Pfam PF01729 Quinolinate phosphoribosyl transferase, C-terminal domain 109 272 4.0E-51 T 28-03-2018 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 CO689_RS01300 f0513f46a558f374eda673fd248d3599 277 Pfam PF02749 Quinolinate phosphoribosyl transferase, N-terminal domain 21 107 4.9E-23 T 28-03-2018 IPR022412 Quinolinate phosphoribosyl transferase, N-terminal GO:0016763 Reactome: R-HSA-196807 CO689_RS01300 f0513f46a558f374eda673fd248d3599 277 SUPERFAMILY SSF51690 109 274 1.29E-48 T 28-03-2018 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 CO689_RS01300 f0513f46a558f374eda673fd248d3599 277 TIGRFAM TIGR00078 nadC: nicotinate-nucleotide diphosphorylase (carboxylating) 11 274 4.7E-89 T 28-03-2018 IPR004393 Nicotinate-nucleotide pyrophosphorylase GO:0004514|GO:0019363 KEGG: 00760+2.4.2.19|MetaCyc: PWY-5316|MetaCyc: PWY-5653|MetaCyc: PWY-7342|Reactome: R-HSA-196807 CO689_RS11535 369341f47b6e03c77b3e137eb7287375 77 Hamap MF_01217 Acyl carrier protein [acpP]. 2 76 22.613 T 28-03-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 CO689_RS11535 369341f47b6e03c77b3e137eb7287375 77 TIGRFAM TIGR00517 acyl_carrier: acyl carrier protein 4 74 1.1E-32 T 28-03-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 CO689_RS11535 369341f47b6e03c77b3e137eb7287375 77 Gene3D G3DSA:1.10.1200.10 1 77 1.4E-25 T 28-03-2018 CO689_RS11535 369341f47b6e03c77b3e137eb7287375 77 SUPERFAMILY SSF47336 4 75 2.75E-23 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CO689_RS11535 369341f47b6e03c77b3e137eb7287375 77 ProSitePatterns PS00012 Phosphopantetheine attachment site. 31 46 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site CO689_RS11535 369341f47b6e03c77b3e137eb7287375 77 Pfam PF00550 Phosphopantetheine attachment site 5 72 2.7E-16 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CO689_RS11535 369341f47b6e03c77b3e137eb7287375 77 ProDom PD000887 CARRIER ACYL PHOSPHOPANTETHEINE ACP ACID FATTY BIOSYNTHESIS LIPID SYNTHESIS CHLOROPLAST 34 74 1.0E-10 T 28-03-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 CO689_RS02115 4bc0928ae405b347163cbdc10a478da0 45 SMART SM00794 1 45 1.6E-22 T 28-03-2018 IPR009229 Staphylococcal AgrD CO689_RS02115 4bc0928ae405b347163cbdc10a478da0 45 Pfam PF05931 Staphylococcal AgrD protein 1 44 4.3E-24 T 28-03-2018 IPR009229 Staphylococcal AgrD CO689_RS02115 4bc0928ae405b347163cbdc10a478da0 45 TIGRFAM TIGR04223 quorum_AgrD: cyclic lactone autoinducer peptide 7 41 1.2E-9 T 28-03-2018 IPR009229 Staphylococcal AgrD CO689_RS01960 3d9124b400b058617c713f009c58e8fe 296 SUPERFAMILY SSF52540 10 224 1.11E-42 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CO689_RS01960 3d9124b400b058617c713f009c58e8fe 296 SMART SM00382 29 215 9.2E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain CO689_RS01960 3d9124b400b058617c713f009c58e8fe 296 Gene3D G3DSA:3.40.50.300 2 283 1.1E-44 T 28-03-2018 CO689_RS01960 3d9124b400b058617c713f009c58e8fe 296 Pfam PF00005 ABC transporter 20 159 4.2E-24 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CO689_RS03955 bfe82466d34a2cf60d464c1295646f46 191 SUPERFAMILY SSF89155 34 178 7.72E-20 T 28-03-2018 IPR020945 DMSO/Nitrate reductase chaperone CO689_RS03955 bfe82466d34a2cf60d464c1295646f46 191 Pfam PF02613 Nitrate reductase delta subunit 56 133 1.2E-5 T 28-03-2018 IPR020945 DMSO/Nitrate reductase chaperone CO689_RS03955 bfe82466d34a2cf60d464c1295646f46 191 Gene3D G3DSA:1.10.3480.10 18 186 9.4E-17 T 28-03-2018 IPR020945 DMSO/Nitrate reductase chaperone CO689_RS00905 e138e33f8edb97227cbe52965360c480 146 TIGRFAM TIGR03563 perox_SACOL1771: peroxiredoxin, SACOL1771 subfamily 4 141 1.3E-60 T 28-03-2018 IPR019905 Peroxiredoxin OsmC-like protein, Firmicutes CO689_RS00905 e138e33f8edb97227cbe52965360c480 146 Pfam PF02566 OsmC-like protein 40 141 1.1E-18 T 28-03-2018 IPR003718 OsmC/Ohr family CO689_RS00905 e138e33f8edb97227cbe52965360c480 146 Gene3D G3DSA:3.30.300.20 1 145 2.6E-29 T 28-03-2018 IPR015946 K homology domain-like, alpha/beta CO689_RS00905 e138e33f8edb97227cbe52965360c480 146 SUPERFAMILY SSF82784 3 141 1.07E-33 T 28-03-2018 IPR003718 OsmC/Ohr family CO689_RS01405 7b18592c3495fb4f886ac7fb6f70123c 384 Pfam PF07730 Histidine kinase 180 243 3.8E-19 T 28-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 CO689_RS01405 7b18592c3495fb4f886ac7fb6f70123c 384 Gene3D G3DSA:3.30.565.10 237 376 2.4E-22 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CO689_RS01405 7b18592c3495fb4f886ac7fb6f70123c 384 SUPERFAMILY SSF55874 247 368 2.75E-16 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CO689_RS01405 7b18592c3495fb4f886ac7fb6f70123c 384 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 279 369 8.7E-7 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CO689_RS01405 7b18592c3495fb4f886ac7fb6f70123c 384 SUPERFAMILY SSF55781 25 176 3.05E-17 T 28-03-2018 IPR029016 GAF domain-like CO689_RS01405 7b18592c3495fb4f886ac7fb6f70123c 384 Gene3D G3DSA:3.30.450.40 4 194 5.4E-18 T 28-03-2018 IPR029016 GAF domain-like CO689_RS01405 7b18592c3495fb4f886ac7fb6f70123c 384 Pfam PF13185 GAF domain 23 163 2.4E-14 T 28-03-2018 IPR003018 GAF domain GO:0005515 CO689_RS01405 7b18592c3495fb4f886ac7fb6f70123c 384 SMART SM00065 22 173 0.0077 T 28-03-2018 IPR003018 GAF domain GO:0005515 CO689_RS07095 f68a7c5410ac6bad4ae2cc99b8a6b8b0 295 SUPERFAMILY SSF50182 122 190 2.65E-12 T 28-03-2018 IPR010920 LSM domain CO689_RS07095 f68a7c5410ac6bad4ae2cc99b8a6b8b0 295 SUPERFAMILY SSF82861 55 120 8.5E-16 T 28-03-2018 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 CO689_RS07095 f68a7c5410ac6bad4ae2cc99b8a6b8b0 295 Gene3D G3DSA:3.30.70.100 192 286 7.5E-7 T 28-03-2018 CO689_RS07095 f68a7c5410ac6bad4ae2cc99b8a6b8b0 295 SUPERFAMILY SSF82689 196 286 3.14E-7 T 28-03-2018 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 CO689_RS07095 f68a7c5410ac6bad4ae2cc99b8a6b8b0 295 Gene3D G3DSA:2.30.30.60 137 191 1.3E-13 T 28-03-2018 CO689_RS07095 f68a7c5410ac6bad4ae2cc99b8a6b8b0 295 Pfam PF00924 Mechanosensitive ion channel 78 280 1.5E-37 T 28-03-2018 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 CO689_RS00890 03834a43b78b45483fd358149e63eceb 201 Gene3D G3DSA:1.10.1050.10 1 97 1.2E-37 T 28-03-2018 CO689_RS00890 03834a43b78b45483fd358149e63eceb 201 TIGRFAM TIGR01017 rpsD_bact: ribosomal protein uS4 3 199 6.8E-81 T 28-03-2018 IPR005709 Ribosomal protein S4, bacterial-type GO:0003735|GO:0006412|GO:0015935 CO689_RS00890 03834a43b78b45483fd358149e63eceb 201 Gene3D G3DSA:1.10.1050.10 142 199 5.4E-17 T 28-03-2018 CO689_RS00890 03834a43b78b45483fd358149e63eceb 201 Pfam PF01479 S4 domain 92 139 7.6E-20 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CO689_RS00890 03834a43b78b45483fd358149e63eceb 201 SUPERFAMILY SSF55174 3 199 1.57E-66 T 28-03-2018 CO689_RS00890 03834a43b78b45483fd358149e63eceb 201 Hamap MF_01306_B 30S ribosomal protein S4 [rpsD]. 1 200 34.626 T 28-03-2018 IPR005709 Ribosomal protein S4, bacterial-type GO:0003735|GO:0006412|GO:0015935 CO689_RS00890 03834a43b78b45483fd358149e63eceb 201 SMART SM00363 92 156 1.0E-18 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CO689_RS00890 03834a43b78b45483fd358149e63eceb 201 SMART SM01390 3 91 4.6E-44 T 28-03-2018 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 CO689_RS00890 03834a43b78b45483fd358149e63eceb 201 Gene3D G3DSA:3.10.290.10 98 141 1.4E-16 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CO689_RS00890 03834a43b78b45483fd358149e63eceb 201 Pfam PF00163 Ribosomal protein S4/S9 N-terminal domain 3 90 1.9E-27 T 28-03-2018 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 CO689_RS10180 354d95842266f82328bdb57c25e3b22a 326 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 247 282 2.3E-8 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CO689_RS10180 354d95842266f82328bdb57c25e3b22a 326 ProSitePatterns PS00211 ABC transporters family signature. 168 182 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CO689_RS10180 354d95842266f82328bdb57c25e3b22a 326 Gene3D G3DSA:3.40.50.300 18 325 8.2E-79 T 28-03-2018 CO689_RS10180 354d95842266f82328bdb57c25e3b22a 326 SUPERFAMILY SSF52540 21 267 8.23E-74 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CO689_RS10180 354d95842266f82328bdb57c25e3b22a 326 SMART SM00382 51 253 2.2E-14 T 28-03-2018 IPR003593 AAA+ ATPase domain CO689_RS10180 354d95842266f82328bdb57c25e3b22a 326 Pfam PF00005 ABC transporter 43 195 2.5E-32 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CO689_RS13850 2c13667b65387add2bd0bfc2b862e0b8 290 SUPERFAMILY SSF52096 30 285 1.07E-80 T 28-03-2018 IPR029045 ClpP/crotonase-like domain CO689_RS13850 2c13667b65387add2bd0bfc2b862e0b8 290 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 165 183 4.2E-37 T 28-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CO689_RS13850 2c13667b65387add2bd0bfc2b862e0b8 290 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 253 262 4.2E-37 T 28-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CO689_RS13850 2c13667b65387add2bd0bfc2b862e0b8 290 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 202 219 4.2E-37 T 28-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CO689_RS13850 2c13667b65387add2bd0bfc2b862e0b8 290 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 131 145 4.2E-37 T 28-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CO689_RS13850 2c13667b65387add2bd0bfc2b862e0b8 290 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 231 242 4.2E-37 T 28-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CO689_RS13850 2c13667b65387add2bd0bfc2b862e0b8 290 Gene3D G3DSA:3.90.226.10 17 289 3.5E-71 T 28-03-2018 CO689_RS13850 2c13667b65387add2bd0bfc2b862e0b8 290 Hamap MF_01395 Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, chloroplastic [accD]. 3 283 38.547 T 28-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CO689_RS13850 2c13667b65387add2bd0bfc2b862e0b8 290 Pfam PF01039 Carboxyl transferase domain 62 244 4.0E-17 T 28-03-2018 IPR034733 Acetyl-CoA carboxylase KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388|Reactome: R-HSA-196780 CO689_RS13850 2c13667b65387add2bd0bfc2b862e0b8 290 TIGRFAM TIGR00515 accD: acetyl-CoA carboxylase, carboxyl transferase, beta subunit 13 284 1.0E-123 T 28-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CO689_RS02260 6d250693335b4393df427fc5bba44af9 158 Hamap MF_00638 Serine-protein kinase RsbW [rsbW]. 2 157 37.17 T 28-03-2018 IPR010193 Serine-protein kinase RsbW GO:0004674|GO:0005524|GO:0006468|GO:0016989|GO:0045892 KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1 CO689_RS02260 6d250693335b4393df427fc5bba44af9 158 Gene3D G3DSA:3.30.565.10 3 156 3.4E-12 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CO689_RS02260 6d250693335b4393df427fc5bba44af9 158 SUPERFAMILY SSF55874 35 134 2.88E-13 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CO689_RS02260 6d250693335b4393df427fc5bba44af9 158 Pfam PF13581 Histidine kinase-like ATPase domain 12 141 6.7E-28 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CO689_RS02260 6d250693335b4393df427fc5bba44af9 158 TIGRFAM TIGR01924 rsbW_low_gc: anti-sigma B factor 1 154 1.3E-74 T 28-03-2018 IPR010193 Serine-protein kinase RsbW GO:0004674|GO:0005524|GO:0006468|GO:0016989|GO:0045892 KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1 CO689_RS08885 45f31229991d2ec6c6b0a4f05ae0dba7 237 TIGRFAM TIGR03365 Bsubt_queE: 7-cyano-7-deazaguanosine (preQ0) biosynthesis protein QueE 3 237 9.2E-112 T 28-03-2018 IPR017742 7-carboxy-7-deazaguanine synthase KEGG: 00790+4.3.99.3|MetaCyc: PWY-6703 CO689_RS08885 45f31229991d2ec6c6b0a4f05ae0dba7 237 PIRSF PIRSF000370 2 237 1.6E-48 T 28-03-2018 IPR024924 7-carboxy-7-deazaguanine synthase-like KEGG: 00790+4.3.99.3|MetaCyc: PWY-6703 CO689_RS08885 45f31229991d2ec6c6b0a4f05ae0dba7 237 SUPERFAMILY SSF102114 23 124 1.96E-11 T 28-03-2018 CO689_RS08885 45f31229991d2ec6c6b0a4f05ae0dba7 237 Pfam PF13353 4Fe-4S single cluster domain 15 118 1.3E-9 T 28-03-2018 CO689_RS08885 45f31229991d2ec6c6b0a4f05ae0dba7 237 Gene3D G3DSA:3.80.30.20 21 213 6.7E-15 T 28-03-2018 IPR023404 Radical SAM, alpha/beta horseshoe CO689_RS08885 45f31229991d2ec6c6b0a4f05ae0dba7 237 Pfam PF04055 Radical SAM superfamily 28 123 1.0E-10 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CO689_RS08885 45f31229991d2ec6c6b0a4f05ae0dba7 237 Hamap MF_00917 7-carboxy-7-deazaguanine synthase [queE]. 4 234 32.608 T 28-03-2018 IPR024924 7-carboxy-7-deazaguanine synthase-like KEGG: 00790+4.3.99.3|MetaCyc: PWY-6703 CO689_RS01665 10c7b9bee2752576d28797a2f965d9b8 267 Hamap MF_01114 Regulatory protein RecX [recX]. 42 208 14.843 T 28-03-2018 IPR003783 Regulatory protein RecX GO:0006282 CO689_RS01665 10c7b9bee2752576d28797a2f965d9b8 267 Gene3D G3DSA:1.10.10.10 214 262 1.7E-5 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS01665 10c7b9bee2752576d28797a2f965d9b8 267 Gene3D G3DSA:1.10.10.10 158 205 2.9E-7 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS01665 10c7b9bee2752576d28797a2f965d9b8 267 Pfam PF02631 RecX family 84 202 1.8E-24 T 28-03-2018 IPR003783 Regulatory protein RecX GO:0006282 CO689_RS01665 10c7b9bee2752576d28797a2f965d9b8 267 Gene3D G3DSA:1.10.10.10 108 153 3.7E-5 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS01665 10c7b9bee2752576d28797a2f965d9b8 267 Gene3D G3DSA:1.10.10.10 44 107 5.5E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS10595 f80bee0e85f32fa1e5a4c93d67d574da 383 SUPERFAMILY SSF56601 61 362 1.57E-59 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CO689_RS10595 f80bee0e85f32fa1e5a4c93d67d574da 383 Pfam PF00144 Beta-lactamase 79 362 2.0E-42 T 28-03-2018 IPR001466 Beta-lactamase-related CO689_RS10595 f80bee0e85f32fa1e5a4c93d67d574da 383 Gene3D G3DSA:3.40.710.10 56 375 2.2E-50 T 28-03-2018 CO689_RS04650 6ecdfc93603956d484dc9748fa4a8104 147 Pfam PF00364 Biotin-requiring enzyme 72 145 5.5E-19 T 28-03-2018 IPR000089 Biotin/lipoyl attachment CO689_RS04650 6ecdfc93603956d484dc9748fa4a8104 147 SUPERFAMILY SSF51230 72 146 1.83E-19 T 28-03-2018 IPR011053 Single hybrid motif CO689_RS04650 6ecdfc93603956d484dc9748fa4a8104 147 Gene3D G3DSA:2.40.50.100 61 147 9.3E-16 T 28-03-2018 CO689_RS04650 6ecdfc93603956d484dc9748fa4a8104 147 ProSitePatterns PS00188 Biotin-requiring enzymes attachment site. 103 120 - T 28-03-2018 IPR001882 Biotin-binding site Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CO689_RS10325 87066ef507ae61e13cc1fe4e34454637 494 SUPERFAMILY SSF63418 12 97 3.4E-19 T 28-03-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 CO689_RS10325 87066ef507ae61e13cc1fe4e34454637 494 Hamap MF_00208 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase [murE]. 1 484 30.744 T 28-03-2018 IPR005761 UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase GO:0005524|GO:0005737|GO:0008360|GO:0016881|GO:0051301 CO689_RS10325 87066ef507ae61e13cc1fe4e34454637 494 Pfam PF02875 Mur ligase family, glutamate ligase domain 332 414 1.2E-17 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CO689_RS10325 87066ef507ae61e13cc1fe4e34454637 494 Gene3D G3DSA:3.40.1390.10 1 98 1.1E-22 T 28-03-2018 CO689_RS10325 87066ef507ae61e13cc1fe4e34454637 494 Pfam PF08245 Mur ligase middle domain 108 311 1.0E-51 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CO689_RS10325 87066ef507ae61e13cc1fe4e34454637 494 SUPERFAMILY SSF53623 99 331 1.57E-68 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CO689_RS10325 87066ef507ae61e13cc1fe4e34454637 494 Gene3D G3DSA:3.90.190.20 337 491 1.6E-36 T 28-03-2018 CO689_RS10325 87066ef507ae61e13cc1fe4e34454637 494 Gene3D G3DSA:3.40.1190.10 99 336 4.4E-57 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CO689_RS10325 87066ef507ae61e13cc1fe4e34454637 494 TIGRFAM TIGR01085 murE: UDP-N-acetylmuramyl-tripeptide synthetase 21 475 1.7E-130 T 28-03-2018 IPR005761 UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase GO:0005524|GO:0005737|GO:0008360|GO:0016881|GO:0051301 CO689_RS10325 87066ef507ae61e13cc1fe4e34454637 494 Pfam PF01225 Mur ligase family, catalytic domain 25 80 1.1E-8 T 28-03-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 CO689_RS10325 87066ef507ae61e13cc1fe4e34454637 494 SUPERFAMILY SSF53244 332 468 3.66E-32 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CO689_RS13805 51ce46f8847a8a9c2b53a29fc2b50b33 876 Gene3D G3DSA:3.30.420.10 306 491 7.0E-19 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CO689_RS13805 51ce46f8847a8a9c2b53a29fc2b50b33 876 SUPERFAMILY SSF47807 171 287 7.03E-31 T 28-03-2018 IPR020045 5'-3' exonuclease, C-terminal domain GO:0003677|GO:0003824 CO689_RS13805 51ce46f8847a8a9c2b53a29fc2b50b33 876 SMART SM00482 633 840 5.8E-110 T 28-03-2018 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CO689_RS13805 51ce46f8847a8a9c2b53a29fc2b50b33 876 PRINTS PR00868 DNA-polymerase family A (pol I) signature 678 691 1.0E-81 T 28-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CO689_RS13805 51ce46f8847a8a9c2b53a29fc2b50b33 876 PRINTS PR00868 DNA-polymerase family A (pol I) signature 823 836 1.0E-81 T 28-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CO689_RS13805 51ce46f8847a8a9c2b53a29fc2b50b33 876 PRINTS PR00868 DNA-polymerase family A (pol I) signature 602 624 1.0E-81 T 28-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CO689_RS13805 51ce46f8847a8a9c2b53a29fc2b50b33 876 PRINTS PR00868 DNA-polymerase family A (pol I) signature 625 640 1.0E-81 T 28-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CO689_RS13805 51ce46f8847a8a9c2b53a29fc2b50b33 876 PRINTS PR00868 DNA-polymerase family A (pol I) signature 702 727 1.0E-81 T 28-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CO689_RS13805 51ce46f8847a8a9c2b53a29fc2b50b33 876 PRINTS PR00868 DNA-polymerase family A (pol I) signature 648 671 1.0E-81 T 28-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CO689_RS13805 51ce46f8847a8a9c2b53a29fc2b50b33 876 PRINTS PR00868 DNA-polymerase family A (pol I) signature 739 750 1.0E-81 T 28-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CO689_RS13805 51ce46f8847a8a9c2b53a29fc2b50b33 876 PRINTS PR00868 DNA-polymerase family A (pol I) signature 761 772 1.0E-81 T 28-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CO689_RS13805 51ce46f8847a8a9c2b53a29fc2b50b33 876 PRINTS PR00868 DNA-polymerase family A (pol I) signature 793 809 1.0E-81 T 28-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CO689_RS13805 51ce46f8847a8a9c2b53a29fc2b50b33 876 ProSitePatterns PS00447 DNA polymerase family A signature. 702 721 - T 28-03-2018 IPR019760 DNA-directed DNA polymerase, family A, conserved site GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CO689_RS13805 51ce46f8847a8a9c2b53a29fc2b50b33 876 Gene3D G3DSA:1.10.150.20 185 263 4.4E-29 T 28-03-2018 CO689_RS13805 51ce46f8847a8a9c2b53a29fc2b50b33 876 SUPERFAMILY SSF56672 470 876 1.56E-156 T 28-03-2018 CO689_RS13805 51ce46f8847a8a9c2b53a29fc2b50b33 876 Gene3D G3DSA:1.20.1060.10 492 603 6.8E-36 T 28-03-2018 CO689_RS13805 51ce46f8847a8a9c2b53a29fc2b50b33 876 SMART SM00475 2 262 5.8E-140 T 28-03-2018 IPR002421 5'-3' exonuclease, N-terminal GO:0003677 CO689_RS13805 51ce46f8847a8a9c2b53a29fc2b50b33 876 Pfam PF02739 5'-3' exonuclease, N-terminal resolvase-like domain 3 168 1.0E-53 T 28-03-2018 IPR020046 5'-3' exonuclease, alpha-helical arch, N-terminal GO:0003677 CO689_RS13805 51ce46f8847a8a9c2b53a29fc2b50b33 876 Pfam PF00476 DNA polymerase family A 499 874 6.7E-158 T 28-03-2018 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CO689_RS13805 51ce46f8847a8a9c2b53a29fc2b50b33 876 TIGRFAM TIGR00593 pola: DNA polymerase I 4 876 0.0 T 28-03-2018 IPR018320 DNA polymerase 1 GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CO689_RS13805 51ce46f8847a8a9c2b53a29fc2b50b33 876 Gene3D G3DSA:3.30.70.370 604 692 5.4E-17 T 28-03-2018 CO689_RS13805 51ce46f8847a8a9c2b53a29fc2b50b33 876 Gene3D G3DSA:3.30.70.370 702 876 1.9E-52 T 28-03-2018 CO689_RS13805 51ce46f8847a8a9c2b53a29fc2b50b33 876 Gene3D G3DSA:3.40.50.1010 2 184 1.9E-65 T 28-03-2018 IPR029060 PIN domain-like CO689_RS13805 51ce46f8847a8a9c2b53a29fc2b50b33 876 SMART SM00279 173 208 1.1E-15 T 28-03-2018 IPR008918 Helix-hairpin-helix motif, class 2 GO:0003677|GO:0003824 CO689_RS13805 51ce46f8847a8a9c2b53a29fc2b50b33 876 Pfam PF01367 5'-3' exonuclease, C-terminal SAM fold 172 261 1.6E-33 T 28-03-2018 IPR020045 5'-3' exonuclease, C-terminal domain GO:0003677|GO:0003824 CO689_RS13805 51ce46f8847a8a9c2b53a29fc2b50b33 876 SUPERFAMILY SSF53098 311 468 6.37E-34 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CO689_RS13805 51ce46f8847a8a9c2b53a29fc2b50b33 876 SMART SM00474 302 467 0.0035 T 28-03-2018 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 CO689_RS13805 51ce46f8847a8a9c2b53a29fc2b50b33 876 SUPERFAMILY SSF88723 2 168 9.03E-53 T 28-03-2018 IPR029060 PIN domain-like CO689_RS02075 e5960120b7688f7e43d41ac8df67bc6a 175 SUPERFAMILY SSF47413 1 64 2.21E-18 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CO689_RS02075 e5960120b7688f7e43d41ac8df67bc6a 175 Gene3D G3DSA:1.10.260.40 1 170 1.6E-20 T 28-03-2018 CO689_RS02075 e5960120b7688f7e43d41ac8df67bc6a 175 SMART SM00530 6 61 6.1E-17 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CO689_RS02075 e5960120b7688f7e43d41ac8df67bc6a 175 Pfam PF01381 Helix-turn-helix 7 61 6.3E-17 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CO689_RS11400 9597a3170ea4b26cb3104e9cfa860a0a 76 SMART SM01409 8 62 4.7E-13 T 28-03-2018 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708 CO689_RS11400 9597a3170ea4b26cb3104e9cfa860a0a 76 Pfam PF01192 RNA polymerase Rpb6 8 61 4.4E-14 T 28-03-2018 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708 CO689_RS11400 9597a3170ea4b26cb3104e9cfa860a0a 76 Hamap MF_00366 DNA-directed RNA polymerase subunit omega [rpoZ]. 1 63 13.397 T 28-03-2018 IPR003716 DNA-directed RNA polymerase, omega subunit GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CO689_RS11400 9597a3170ea4b26cb3104e9cfa860a0a 76 SUPERFAMILY SSF63562 1 68 8.55E-18 T 28-03-2018 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708 CO689_RS11400 9597a3170ea4b26cb3104e9cfa860a0a 76 Gene3D G3DSA:3.90.940.10 1 76 2.6E-18 T 28-03-2018 IPR012293 RNA polymerase subunit, RPB6/omega GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708 CO689_RS11400 9597a3170ea4b26cb3104e9cfa860a0a 76 TIGRFAM TIGR00690 rpoZ: DNA-directed RNA polymerase, omega subunit 1 60 4.4E-13 T 28-03-2018 IPR003716 DNA-directed RNA polymerase, omega subunit GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CO689_RS04265 32f9f2ec1c790efc591b6320fecbd49f 232 Pfam PF03306 Alpha-acetolactate decarboxylase 2 220 1.1E-77 T 28-03-2018 IPR005128 Alpha-acetolactate decarboxylase GO:0045151|GO:0047605 KEGG: 00650+4.1.1.5|KEGG: 00660+4.1.1.5|MetaCyc: PWY-5939 CO689_RS04265 32f9f2ec1c790efc591b6320fecbd49f 232 Gene3D G3DSA:3.30.1330.80 90 196 1.3E-41 T 28-03-2018 CO689_RS04265 32f9f2ec1c790efc591b6320fecbd49f 232 TIGRFAM TIGR01252 acetolac_decarb: alpha-acetolactate decarboxylase 2 232 1.5E-78 T 28-03-2018 IPR005128 Alpha-acetolactate decarboxylase GO:0045151|GO:0047605 KEGG: 00650+4.1.1.5|KEGG: 00660+4.1.1.5|MetaCyc: PWY-5939 CO689_RS04265 32f9f2ec1c790efc591b6320fecbd49f 232 Gene3D G3DSA:3.30.1330.80 1 89 2.1E-30 T 28-03-2018 CO689_RS04265 32f9f2ec1c790efc591b6320fecbd49f 232 SUPERFAMILY SSF117856 2 232 2.62E-76 T 28-03-2018 CO689_RS04265 32f9f2ec1c790efc591b6320fecbd49f 232 PIRSF PIRSF001332 1 232 1.9E-90 T 28-03-2018 IPR005128 Alpha-acetolactate decarboxylase GO:0045151|GO:0047605 KEGG: 00650+4.1.1.5|KEGG: 00660+4.1.1.5|MetaCyc: PWY-5939 CO689_RS05345 306d18fcbf906033f2ad0022b39cde74 401 Gene3D G3DSA:3.40.640.10 1 264 1.0E-46 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CO689_RS05345 306d18fcbf906033f2ad0022b39cde74 401 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 10 392 2.3E-94 T 28-03-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase CO689_RS05345 306d18fcbf906033f2ad0022b39cde74 401 PIRSF PIRSF000390 1 398 5.5E-92 T 28-03-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase CO689_RS05345 306d18fcbf906033f2ad0022b39cde74 401 SUPERFAMILY SSF53383 2 397 6.79E-97 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CO689_RS05345 306d18fcbf906033f2ad0022b39cde74 401 Gene3D G3DSA:3.90.1150.10 265 398 3.2E-34 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CO689_RS03025 f47582a002c4555077c69e6a774413dd 129 Hamap MF_01310 30S ribosomal protein S11 [rpsK]. 3 129 34.297 T 28-03-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 CO689_RS03025 f47582a002c4555077c69e6a774413dd 129 PIRSF PIRSF002131 1 129 9.5E-54 T 28-03-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 CO689_RS03025 f47582a002c4555077c69e6a774413dd 129 SUPERFAMILY SSF53137 14 129 2.88E-49 T 28-03-2018 CO689_RS03025 f47582a002c4555077c69e6a774413dd 129 Gene3D G3DSA:3.30.420.80 2 129 2.1E-44 T 28-03-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 CO689_RS03025 f47582a002c4555077c69e6a774413dd 129 ProSitePatterns PS00054 Ribosomal protein S11 signature. 97 119 - T 28-03-2018 IPR018102 Ribosomal S11, conserved site CO689_RS03025 f47582a002c4555077c69e6a774413dd 129 Pfam PF00411 Ribosomal protein S11 19 128 9.0E-51 T 28-03-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 CO689_RS03025 f47582a002c4555077c69e6a774413dd 129 TIGRFAM TIGR03632 uS11_bact: ribosomal protein uS11 10 126 3.2E-59 T 28-03-2018 IPR019981 Ribosomal protein S11, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 CO689_RS00230 a99855cabe175d33f28ade08c33cb300 115 SMART SM00418 34 113 4.3E-22 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CO689_RS00230 a99855cabe175d33f28ade08c33cb300 115 Gene3D G3DSA:1.10.10.10 1 114 2.0E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS00230 a99855cabe175d33f28ade08c33cb300 115 Pfam PF01022 Bacterial regulatory protein, arsR family 41 85 8.6E-14 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CO689_RS00230 a99855cabe175d33f28ade08c33cb300 115 SUPERFAMILY SSF46785 20 109 5.17E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS00230 a99855cabe175d33f28ade08c33cb300 115 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 56 67 3.4E-14 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CO689_RS00230 a99855cabe175d33f28ade08c33cb300 115 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 84 99 3.4E-14 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CO689_RS00230 a99855cabe175d33f28ade08c33cb300 115 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 36 51 3.4E-14 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CO689_RS00230 a99855cabe175d33f28ade08c33cb300 115 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 69 84 3.4E-14 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CO689_RS00230 a99855cabe175d33f28ade08c33cb300 115 ProSitePatterns PS00846 Bacterial regulatory proteins, arsR family signature. 58 76 - T 28-03-2018 IPR018334 ArsR-type transcription regulator, HTH motif GO:0003700|GO:0005622|GO:0006355 CO689_RS01365 99736396bc9e09071448c55f7f447867 313 Gene3D G3DSA:2.40.50.140 18 101 8.6E-9 T 28-03-2018 CO689_RS01365 99736396bc9e09071448c55f7f447867 313 Pfam PF01336 OB-fold nucleic acid binding domain 27 88 4.6E-7 T 28-03-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 CO689_RS01365 99736396bc9e09071448c55f7f447867 313 Pfam PF01966 HD domain 161 277 1.4E-11 T 28-03-2018 IPR006674 HD domain CO689_RS01365 99736396bc9e09071448c55f7f447867 313 SMART SM00471 155 287 5.3E-5 T 28-03-2018 IPR003607 HD/PDEase domain CO689_RS01365 99736396bc9e09071448c55f7f447867 313 SUPERFAMILY SSF109604 138 280 2.48E-16 T 28-03-2018 CO689_RS01365 99736396bc9e09071448c55f7f447867 313 Gene3D G3DSA:1.10.3210.10 120 309 1.1E-15 T 28-03-2018 CO689_RS01240 1995cad1c918c685e7195b532e62dda9 208 Gene3D G3DSA:3.40.190.10 1 56 9.0E-4 T 28-03-2018 CO689_RS10830 84ed04db86c2383522c956f12ce9832a 219 Gene3D G3DSA:3.30.70.1450 136 218 2.4E-22 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 CO689_RS10830 84ed04db86c2383522c956f12ce9832a 219 Pfam PF02080 TrkA-C domain 150 217 1.0E-16 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 CO689_RS10830 84ed04db86c2383522c956f12ce9832a 219 SUPERFAMILY SSF116726 131 215 8.89E-21 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 CO689_RS10830 84ed04db86c2383522c956f12ce9832a 219 Gene3D G3DSA:3.40.50.720 3 135 8.6E-24 T 28-03-2018 CO689_RS10830 84ed04db86c2383522c956f12ce9832a 219 SUPERFAMILY SSF51735 4 133 1.04E-37 T 28-03-2018 IPR016040 NAD(P)-binding domain CO689_RS10830 84ed04db86c2383522c956f12ce9832a 219 Pfam PF02254 TrkA-N domain 5 120 1.3E-29 T 28-03-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 CO689_RS13855 a602d92da5a6f8e32468d69cb25ba84b 409 SMART SM01274 15 148 1.4E-80 T 28-03-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 CO689_RS13855 a602d92da5a6f8e32468d69cb25ba84b 409 SMART SM00919 160 384 2.7E-132 T 28-03-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 CO689_RS13855 a602d92da5a6f8e32468d69cb25ba84b 409 SUPERFAMILY SSF53223 7 158 1.22E-54 T 28-03-2018 CO689_RS13855 a602d92da5a6f8e32468d69cb25ba84b 409 PIRSF PIRSF000106 41 406 3.9E-87 T 28-03-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 CO689_RS13855 a602d92da5a6f8e32468d69cb25ba84b 409 PRINTS PR00072 Malic enzyme signature 156 172 8.4E-9 T 28-03-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 CO689_RS13855 a602d92da5a6f8e32468d69cb25ba84b 409 PRINTS PR00072 Malic enzyme signature 187 203 8.4E-9 T 28-03-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 CO689_RS13855 a602d92da5a6f8e32468d69cb25ba84b 409 PRINTS PR00072 Malic enzyme signature 77 99 8.4E-9 T 28-03-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 CO689_RS13855 a602d92da5a6f8e32468d69cb25ba84b 409 SUPERFAMILY SSF51735 160 401 1.38E-83 T 28-03-2018 IPR016040 NAD(P)-binding domain CO689_RS13855 a602d92da5a6f8e32468d69cb25ba84b 409 Gene3D G3DSA:3.40.50.10380 3 157 4.4E-41 T 28-03-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 CO689_RS13855 a602d92da5a6f8e32468d69cb25ba84b 409 Pfam PF03949 Malic enzyme, NAD binding domain 162 383 1.1E-24 T 28-03-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 CO689_RS13855 a602d92da5a6f8e32468d69cb25ba84b 409 Pfam PF00390 Malic enzyme, N-terminal domain 18 148 2.5E-29 T 28-03-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 CO689_RS13855 a602d92da5a6f8e32468d69cb25ba84b 409 Gene3D G3DSA:3.40.50.720 158 405 3.5E-86 T 28-03-2018 CO689_RS13855 a602d92da5a6f8e32468d69cb25ba84b 409 ProSitePatterns PS00331 Malic enzymes signature. 156 172 - T 28-03-2018 IPR015884 Malic enzyme, conserved site GO:0004471|GO:0055114 CO689_RS11085 9af853257df33b705a347947c9956929 104 PRINTS PR00421 Thioredoxin family signature 28 37 2.5E-8 T 28-03-2018 CO689_RS11085 9af853257df33b705a347947c9956929 104 PRINTS PR00421 Thioredoxin family signature 20 28 2.5E-8 T 28-03-2018 CO689_RS11085 9af853257df33b705a347947c9956929 104 PRINTS PR00421 Thioredoxin family signature 68 79 2.5E-8 T 28-03-2018 CO689_RS11085 9af853257df33b705a347947c9956929 104 SUPERFAMILY SSF52833 3 104 6.93E-39 T 28-03-2018 IPR012336 Thioredoxin-like fold CO689_RS11085 9af853257df33b705a347947c9956929 104 TIGRFAM TIGR01068 thioredoxin: thioredoxin 7 103 2.1E-39 T 28-03-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 CO689_RS11085 9af853257df33b705a347947c9956929 104 ProSitePatterns PS00194 Thioredoxin family active site. 21 39 - T 28-03-2018 IPR017937 Thioredoxin, conserved site GO:0045454 CO689_RS11085 9af853257df33b705a347947c9956929 104 Pfam PF00085 Thioredoxin 4 103 5.4E-33 T 28-03-2018 IPR013766 Thioredoxin domain GO:0045454 CO689_RS11085 9af853257df33b705a347947c9956929 104 Gene3D G3DSA:3.40.30.10 1 104 9.1E-37 T 28-03-2018 CO689_RS11085 9af853257df33b705a347947c9956929 104 PIRSF PIRSF000077 1 104 2.2E-44 T 28-03-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 CO689_RS10095 d4e1b03d9f39b98102a724e6cacba905 188 ProSitePatterns PS00501 Signal peptidases I serine active site. 34 41 - T 28-03-2018 IPR019756 Peptidase S26A, signal peptidase I, serine active site GO:0008236|GO:0016021 Reactome: R-HSA-1799339|Reactome: R-HSA-381771|Reactome: R-HSA-400511|Reactome: R-HSA-422085 CO689_RS10095 d4e1b03d9f39b98102a724e6cacba905 188 TIGRFAM TIGR02227 sigpep_I_bact: signal peptidase I 8 176 6.8E-51 T 28-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 CO689_RS10095 d4e1b03d9f39b98102a724e6cacba905 188 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 75 87 2.8E-20 T 28-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 CO689_RS10095 d4e1b03d9f39b98102a724e6cacba905 188 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 136 155 2.8E-20 T 28-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 CO689_RS10095 d4e1b03d9f39b98102a724e6cacba905 188 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 25 41 2.8E-20 T 28-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 CO689_RS10095 d4e1b03d9f39b98102a724e6cacba905 188 SUPERFAMILY SSF51306 25 181 1.47E-46 T 28-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C CO689_RS10095 d4e1b03d9f39b98102a724e6cacba905 188 Gene3D G3DSA:2.10.109.10 21 187 5.3E-41 T 28-03-2018 CO689_RS10095 d4e1b03d9f39b98102a724e6cacba905 188 ProSitePatterns PS00760 Signal peptidases I lysine active site. 77 89 - T 28-03-2018 IPR019757 Peptidase S26A, signal peptidase I, lysine active site GO:0008236|GO:0016021 CO689_RS10095 d4e1b03d9f39b98102a724e6cacba905 188 ProSitePatterns PS00761 Signal peptidases I signature 3. 141 154 - T 28-03-2018 IPR019758 Peptidase S26A, signal peptidase I, conserved site GO:0008236|GO:0016021 CO689_RS10095 d4e1b03d9f39b98102a724e6cacba905 188 Pfam PF00717 Peptidase S24-like 31 99 1.4E-17 T 28-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C CO689_RS01605 9f2cd48804a6d7a41c6e571777763dfe 150 SUPERFAMILY SSF46785 14 144 9.75E-43 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS01605 9f2cd48804a6d7a41c6e571777763dfe 150 Gene3D G3DSA:1.10.10.10 1 94 5.3E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS01605 9f2cd48804a6d7a41c6e571777763dfe 150 Pfam PF01475 Ferric uptake regulator family 22 139 1.1E-40 T 28-03-2018 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 CO689_RS08960 0aa2a871b9bd95fa61fae2f386ff9991 178 Gene3D G3DSA:3.40.50.1000 60 177 2.3E-31 T 28-03-2018 IPR023214 HAD-like domain CO689_RS08960 0aa2a871b9bd95fa61fae2f386ff9991 178 SUPERFAMILY SSF56784 6 176 1.85E-27 T 28-03-2018 IPR023214 HAD-like domain CO689_RS08960 0aa2a871b9bd95fa61fae2f386ff9991 178 Gene3D G3DSA:1.10.40.40 18 59 2.7E-14 T 28-03-2018 CO689_RS08960 0aa2a871b9bd95fa61fae2f386ff9991 178 Pfam PF06941 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) 6 174 1.6E-40 T 28-03-2018 IPR010708 5'(3')-deoxyribonucleotidase GO:0008253|GO:0009264 Reactome: R-HSA-73621 CO689_RS03950 7b8479de3f029d11b7648ac1a1a64bad 228 TIGRFAM TIGR00351 narI: respiratory nitrate reductase, gamma subunit 1 222 2.1E-68 T 28-03-2018 IPR003816 Nitrate reductase, gamma subunit GO:0008940|GO:0009325|GO:0055114 KEGG: 00910+1.7.99.4 CO689_RS03950 7b8479de3f029d11b7648ac1a1a64bad 228 SUPERFAMILY SSF103501 1 222 8.24E-69 T 28-03-2018 IPR023234 NarG-like domain CO689_RS03950 7b8479de3f029d11b7648ac1a1a64bad 228 Pfam PF02665 Nitrate reductase gamma subunit 3 222 1.7E-85 T 28-03-2018 IPR023234 NarG-like domain CO689_RS03950 7b8479de3f029d11b7648ac1a1a64bad 228 Gene3D G3DSA:1.20.950.20 1 215 1.7E-41 T 28-03-2018 CO689_RS13535 213dd7ea11d4b27fdcee05b0a3f70db5 379 SUPERFAMILY SSF51713 2 369 4.05E-165 T 28-03-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 CO689_RS13535 213dd7ea11d4b27fdcee05b0a3f70db5 379 Hamap MF_00168 Queuine tRNA-ribosyltransferase [tgt]. 4 368 57.664 T 28-03-2018 IPR004803 tRNA-guanine transglycosylase GO:0008479|GO:0101030 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 CO689_RS13535 213dd7ea11d4b27fdcee05b0a3f70db5 379 Gene3D G3DSA:3.20.20.105 1 374 1.3E-163 T 28-03-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 CO689_RS13535 213dd7ea11d4b27fdcee05b0a3f70db5 379 TIGRFAM TIGR00430 Q_tRNA_tgt: tRNA-guanine transglycosylase 6 372 1.2E-181 T 28-03-2018 IPR004803 tRNA-guanine transglycosylase GO:0008479|GO:0101030 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 CO689_RS13535 213dd7ea11d4b27fdcee05b0a3f70db5 379 Pfam PF01702 Queuine tRNA-ribosyltransferase 133 365 5.0E-93 T 28-03-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 CO689_RS13535 213dd7ea11d4b27fdcee05b0a3f70db5 379 TIGRFAM TIGR00449 tgt_general: tRNA-guanine family transglycosylase 6 371 1.7E-172 T 28-03-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 CO689_RS01425 0b0d6e16c5f5e3ae43875977477071b1 199 SUPERFAMILY SSF100950 3 196 9.63E-21 T 28-03-2018 CO689_RS01425 0b0d6e16c5f5e3ae43875977477071b1 199 Gene3D G3DSA:3.40.50.1360 2 127 0.0014 T 28-03-2018 CO689_RS01425 0b0d6e16c5f5e3ae43875977477071b1 199 Gene3D G3DSA:3.40.50.1360 130 199 5.2E-9 T 28-03-2018 CO689_RS08825 7beb631f82c35b1c9c2e3839cc94dc0b 304 TIGRFAM TIGR03168 1-PFK: hexose kinase, 1-phosphofructokinase family 2 300 4.5E-107 T 28-03-2018 IPR017583 Tagatose/fructose phosphokinase GO:0005975|GO:0016773 CO689_RS08825 7beb631f82c35b1c9c2e3839cc94dc0b 304 Gene3D G3DSA:3.40.1190.20 43 300 1.1E-44 T 28-03-2018 IPR029056 Ribokinase-like CO689_RS08825 7beb631f82c35b1c9c2e3839cc94dc0b 304 SUPERFAMILY SSF53613 2 283 4.83E-65 T 28-03-2018 IPR029056 Ribokinase-like CO689_RS08825 7beb631f82c35b1c9c2e3839cc94dc0b 304 TIGRFAM TIGR03828 pfkB: 1-phosphofructokinase 2 300 2.8E-106 T 28-03-2018 IPR022463 Fructose 1-phosphate kinase GO:0008662 KEGG: 00051+2.7.1.56 CO689_RS08825 7beb631f82c35b1c9c2e3839cc94dc0b 304 Pfam PF00294 pfkB family carbohydrate kinase 10 282 1.2E-53 T 28-03-2018 IPR011611 Carbohydrate kinase PfkB CO689_RS08825 7beb631f82c35b1c9c2e3839cc94dc0b 304 PIRSF PIRSF000535 1 303 1.5E-87 T 28-03-2018 IPR017583 Tagatose/fructose phosphokinase GO:0005975|GO:0016773 CO689_RS08825 7beb631f82c35b1c9c2e3839cc94dc0b 304 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 243 256 - T 28-03-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 CO689_RS08825 7beb631f82c35b1c9c2e3839cc94dc0b 304 Gene3D G3DSA:2.20.150.10 9 42 4.4E-16 T 28-03-2018 IPR023314 Tagatose-6-phosphate kinase/1-phosphofructokinase N-terminal domain CO689_RS12570 8f8afd46758374e87af8b01b69bffad0 207 Pfam PF01569 PAP2 superfamily 85 198 4.4E-17 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CO689_RS12570 8f8afd46758374e87af8b01b69bffad0 207 Gene3D G3DSA:1.20.144.10 48 204 1.3E-24 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CO689_RS12570 8f8afd46758374e87af8b01b69bffad0 207 SMART SM00014 84 195 4.5E-22 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CO689_RS12570 8f8afd46758374e87af8b01b69bffad0 207 SUPERFAMILY SSF48317 9 199 2.35E-34 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CO689_RS01795 675c7cce60217774068104730de38698 100 TIGRFAM TIGR00135 gatC: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, C subunit 4 95 4.4E-28 T 28-03-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 CO689_RS01795 675c7cce60217774068104730de38698 100 Pfam PF02686 Glu-tRNAGln amidotransferase C subunit 20 91 2.3E-20 T 28-03-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 CO689_RS01795 675c7cce60217774068104730de38698 100 SUPERFAMILY SSF141000 4 94 7.19E-29 T 28-03-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 CO689_RS01795 675c7cce60217774068104730de38698 100 Hamap MF_00122 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C [gatC]. 3 96 24.613 T 28-03-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 CO689_RS09935 45261e251e9049f7ca65cd65cdb2d8ae 107 PIRSF PIRSF010603 1 107 1.7E-43 T 28-03-2018 IPR009190 Protein of unknown function DUF1462 CO689_RS09935 45261e251e9049f7ca65cd65cdb2d8ae 107 Gene3D G3DSA:3.40.30.30 2 103 2.5E-41 T 28-03-2018 CO689_RS09935 45261e251e9049f7ca65cd65cdb2d8ae 107 Pfam PF07315 Protein of unknown function (DUF1462) 7 101 1.4E-40 T 28-03-2018 IPR009190 Protein of unknown function DUF1462 CO689_RS09935 45261e251e9049f7ca65cd65cdb2d8ae 107 SUPERFAMILY SSF52833 1 105 2.08E-44 T 28-03-2018 IPR012336 Thioredoxin-like fold CO689_RS12685 9c627b1cd43226064ed33279e8a06be8 98 Gene3D G3DSA:1.20.120.440 1 96 3.3E-26 T 28-03-2018 IPR023351 YppE-like domain CO689_RS12685 9c627b1cd43226064ed33279e8a06be8 98 Pfam PF08807 Bacterial domain of unknown function (DUF1798) 1 92 8.9E-25 T 28-03-2018 IPR014913 Protein of unknown function DUF1798 CO689_RS12685 9c627b1cd43226064ed33279e8a06be8 98 SUPERFAMILY SSF140415 6 92 2.49E-23 T 28-03-2018 IPR023351 YppE-like domain CO689_RS08470 c0d85c90fa57002a5183809888566f3c 635 Gene3D G3DSA:3.30.930.10 225 526 5.7E-117 T 28-03-2018 CO689_RS08470 c0d85c90fa57002a5183809888566f3c 635 PRINTS PR01047 Threonyl-tRNA synthetase signature 459 487 4.7E-52 T 28-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 CO689_RS08470 c0d85c90fa57002a5183809888566f3c 635 PRINTS PR01047 Threonyl-tRNA synthetase signature 502 515 4.7E-52 T 28-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 CO689_RS08470 c0d85c90fa57002a5183809888566f3c 635 PRINTS PR01047 Threonyl-tRNA synthetase signature 325 353 4.7E-52 T 28-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 CO689_RS08470 c0d85c90fa57002a5183809888566f3c 635 PRINTS PR01047 Threonyl-tRNA synthetase signature 358 381 4.7E-52 T 28-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 CO689_RS08470 c0d85c90fa57002a5183809888566f3c 635 PRINTS PR01047 Threonyl-tRNA synthetase signature 529 541 4.7E-52 T 28-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 CO689_RS08470 c0d85c90fa57002a5183809888566f3c 635 Hamap MF_00184 Threonine--tRNA ligase [thrS]. 69 630 30.043 T 28-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 CO689_RS08470 c0d85c90fa57002a5183809888566f3c 635 TIGRFAM TIGR00418 thrS: threonine--tRNA ligase 89 626 1.8E-193 T 28-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 CO689_RS08470 c0d85c90fa57002a5183809888566f3c 635 Gene3D G3DSA:3.30.980.10 66 224 6.2E-19 T 28-03-2018 CO689_RS08470 c0d85c90fa57002a5183809888566f3c 635 SUPERFAMILY SSF52954 522 625 1.15E-30 T 28-03-2018 IPR004154 Anticodon-binding CO689_RS08470 c0d85c90fa57002a5183809888566f3c 635 SUPERFAMILY SSF55186 67 236 2.22E-23 T 28-03-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain GO:0000166 CO689_RS08470 c0d85c90fa57002a5183809888566f3c 635 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 319 523 1.1E-38 T 28-03-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 CO689_RS08470 c0d85c90fa57002a5183809888566f3c 635 SUPERFAMILY SSF55681 239 521 1.33E-92 T 28-03-2018 CO689_RS08470 c0d85c90fa57002a5183809888566f3c 635 Pfam PF02824 TGS domain 6 64 1.5E-9 T 28-03-2018 IPR004095 TGS KEGG: 00970+6.1.1.3 CO689_RS08470 c0d85c90fa57002a5183809888566f3c 635 Gene3D G3DSA:3.40.50.800 527 633 2.8E-29 T 28-03-2018 IPR004154 Anticodon-binding CO689_RS08470 c0d85c90fa57002a5183809888566f3c 635 SUPERFAMILY SSF81271 5 64 1.13E-11 T 28-03-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 CO689_RS08470 c0d85c90fa57002a5183809888566f3c 635 Pfam PF03129 Anticodon binding domain 539 625 3.7E-22 T 28-03-2018 IPR004154 Anticodon-binding CO689_RS08470 c0d85c90fa57002a5183809888566f3c 635 Gene3D G3DSA:3.10.20.30 2 65 8.2E-17 T 28-03-2018 IPR012675 Beta-grasp domain CO689_RS12305 aad728083ca1fffa286207047097539a 420 Pfam PF11798 IMS family HHH motif 181 213 1.9E-6 T 28-03-2018 IPR024728 DNA polymerase type-Y, HhH motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5655862|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210 CO689_RS12305 aad728083ca1fffa286207047097539a 420 Gene3D G3DSA:3.30.1490.100 263 370 6.1E-22 T 28-03-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 CO689_RS12305 aad728083ca1fffa286207047097539a 420 Gene3D G3DSA:3.30.70.270 129 185 1.1E-8 T 28-03-2018 CO689_RS12305 aad728083ca1fffa286207047097539a 420 Gene3D G3DSA:3.30.70.270 51 128 1.3E-11 T 28-03-2018 CO689_RS12305 aad728083ca1fffa286207047097539a 420 Gene3D G3DSA:1.10.150.20 186 262 9.5E-18 T 28-03-2018 CO689_RS12305 aad728083ca1fffa286207047097539a 420 SUPERFAMILY SSF100879 270 355 3.53E-8 T 28-03-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 CO689_RS12305 aad728083ca1fffa286207047097539a 420 SUPERFAMILY SSF56672 10 249 1.6E-51 T 28-03-2018 CO689_RS12305 aad728083ca1fffa286207047097539a 420 Pfam PF00817 impB/mucB/samB family 15 165 1.7E-30 T 28-03-2018 IPR001126 UmuC domain GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 CO689_RS12305 aad728083ca1fffa286207047097539a 420 Pfam PF11799 impB/mucB/samB family C-terminal domain 258 361 1.6E-12 T 28-03-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 CO689_RS11230 23dc81fb4de24bf7fb09f0bdbab5f77b 309 Hamap MF_00912 Cell division protein DivIB [divIB]. 1 257 29.203 T 28-03-2018 IPR026580 Cell division protein DivIB CO689_RS11230 23dc81fb4de24bf7fb09f0bdbab5f77b 309 Pfam PF08478 POTRA domain, FtsQ-type 51 119 1.3E-15 T 28-03-2018 IPR013685 POTRA domain, FtsQ-type CO689_RS11230 23dc81fb4de24bf7fb09f0bdbab5f77b 309 Pfam PF03799 Cell division protein FtsQ 127 243 7.8E-12 T 28-03-2018 IPR005548 Cell division protein FtsQ/DivIB CO689_RS00665 b0512566d0ba93b232826138e0855eef 85 Gene3D G3DSA:1.20.1250.20 1 77 2.7E-5 T 28-03-2018 CO689_RS00665 b0512566d0ba93b232826138e0855eef 85 SUPERFAMILY SSF103473 2 77 1.44E-6 T 28-03-2018 IPR020846 Major facilitator superfamily domain CO689_RS07905 f0a06923a8fe52dca53b97cad37cf500 156 Gene3D G3DSA:3.40.630.30 3 155 1.3E-14 T 28-03-2018 CO689_RS07905 f0a06923a8fe52dca53b97cad37cf500 156 Pfam PF00583 Acetyltransferase (GNAT) family 37 135 2.7E-11 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CO689_RS07905 f0a06923a8fe52dca53b97cad37cf500 156 SUPERFAMILY SSF55729 38 154 8.98E-18 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CO689_RS06505 70581a3ba1ba7c43749c2a6fa92b3c03 92 SUPERFAMILY SSF55729 3 90 2.13E-25 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CO689_RS06505 70581a3ba1ba7c43749c2a6fa92b3c03 92 Gene3D G3DSA:3.40.630.30 2 92 3.2E-17 T 28-03-2018 CO689_RS06505 70581a3ba1ba7c43749c2a6fa92b3c03 92 Pfam PF14542 GCN5-related N-acetyl-transferase 10 89 2.3E-24 T 28-03-2018 IPR031165 Yjdj-type Gcn5-related N-acetyltransferase CO689_RS00830 969c41414f9c8c7ea0658d951c9ad8f2 167 PRINTS PR01438 Universal stress protein signature 103 115 3.2E-19 T 28-03-2018 IPR006015 Universal stress protein A CO689_RS00830 969c41414f9c8c7ea0658d951c9ad8f2 167 PRINTS PR01438 Universal stress protein signature 4 22 3.2E-19 T 28-03-2018 IPR006015 Universal stress protein A CO689_RS00830 969c41414f9c8c7ea0658d951c9ad8f2 167 PRINTS PR01438 Universal stress protein signature 121 143 3.2E-19 T 28-03-2018 IPR006015 Universal stress protein A CO689_RS00830 969c41414f9c8c7ea0658d951c9ad8f2 167 SUPERFAMILY SSF52402 4 150 2.43E-36 T 28-03-2018 CO689_RS00830 969c41414f9c8c7ea0658d951c9ad8f2 167 PIRSF PIRSF006276 1 146 2.8E-23 T 28-03-2018 IPR006015 Universal stress protein A CO689_RS00830 969c41414f9c8c7ea0658d951c9ad8f2 167 Gene3D G3DSA:3.40.50.620 2 155 8.4E-37 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CO689_RS00830 969c41414f9c8c7ea0658d951c9ad8f2 167 Pfam PF00582 Universal stress protein family 4 143 8.2E-37 T 28-03-2018 IPR006016 UspA GO:0006950 CO689_RS02140 33f50d6049eea6a587c928c123acfdac 74 SUPERFAMILY SSF64307 2 73 2.22E-19 T 28-03-2018 IPR001455 TusA-like domain CO689_RS02140 33f50d6049eea6a587c928c123acfdac 74 Gene3D G3DSA:3.30.110.40 2 73 9.4E-16 T 28-03-2018 IPR001455 TusA-like domain CO689_RS02140 33f50d6049eea6a587c928c123acfdac 74 Pfam PF01206 Sulfurtransferase TusA 5 73 8.0E-17 T 28-03-2018 IPR001455 TusA-like domain CO689_RS04060 46ea8fd75a1e73e5fffebad937d2e8ba 298 Pfam PF01545 Cation efflux family 15 206 1.4E-41 T 28-03-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 CO689_RS04060 46ea8fd75a1e73e5fffebad937d2e8ba 298 Gene3D G3DSA:1.20.1510.10 9 205 1.9E-33 T 28-03-2018 CO689_RS04060 46ea8fd75a1e73e5fffebad937d2e8ba 298 Gene3D G3DSA:3.30.70.1350 206 288 3.4E-17 T 28-03-2018 IPR027470 Cation efflux protein, cytoplasmic domain CO689_RS04060 46ea8fd75a1e73e5fffebad937d2e8ba 298 Pfam PF16916 Dimerisation domain of Zinc Transporter 215 286 8.8E-17 T 28-03-2018 IPR027470 Cation efflux protein, cytoplasmic domain CO689_RS04060 46ea8fd75a1e73e5fffebad937d2e8ba 298 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 11 287 1.6E-61 T 28-03-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 CO689_RS04060 46ea8fd75a1e73e5fffebad937d2e8ba 298 SUPERFAMILY SSF160240 210 287 6.28E-17 T 28-03-2018 CO689_RS04060 46ea8fd75a1e73e5fffebad937d2e8ba 298 SUPERFAMILY SSF161111 7 208 1.05E-47 T 28-03-2018 CO689_RS11410 57c579b0c691df5736ba0c7545dfdac7 403 SUPERFAMILY SSF102645 190 402 6.67E-72 T 28-03-2018 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 CO689_RS11410 57c579b0c691df5736ba0c7545dfdac7 403 TIGRFAM TIGR00521 coaBC_dfp: phosphopantothenoylcysteine decarboxylase / phosphopantothenate--cysteine ligase 2 398 1.3E-140 T 28-03-2018 IPR005252 Coenzyme A biosynthesis bifunctional protein CoaBC GO:0004632|GO:0004633|GO:0010181|GO:0015937|GO:0015941 KEGG: 00770+4.1.1.36+6.3.2.5|MetaCyc: PWY-7851 CO689_RS11410 57c579b0c691df5736ba0c7545dfdac7 403 Gene3D G3DSA:3.40.50.10300 185 403 6.4E-66 T 28-03-2018 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 CO689_RS11410 57c579b0c691df5736ba0c7545dfdac7 403 Pfam PF02441 Flavoprotein 2 175 9.4E-44 T 28-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 CO689_RS11410 57c579b0c691df5736ba0c7545dfdac7 403 Gene3D G3DSA:3.40.50.1950 1 184 4.4E-55 T 28-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 CO689_RS11410 57c579b0c691df5736ba0c7545dfdac7 403 Pfam PF04127 DNA / pantothenate metabolism flavoprotein 192 372 1.8E-69 T 28-03-2018 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 CO689_RS11410 57c579b0c691df5736ba0c7545dfdac7 403 SUPERFAMILY SSF52507 2 175 6.41E-60 T 28-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 CO689_RS13330 62e81ac9bc8be99781897fa786f69221 324 SUPERFAMILY SSF52540 4 202 3.72E-15 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CO689_RS13330 62e81ac9bc8be99781897fa786f69221 324 Pfam PF06144 DNA polymerase III, delta subunit 8 181 5.0E-43 T 28-03-2018 IPR010372 DNA polymerase III delta, N-terminal GO:0003677|GO:0003887|GO:0006260|GO:0009360 CO689_RS13330 62e81ac9bc8be99781897fa786f69221 324 TIGRFAM TIGR01128 holA: DNA polymerase III, delta subunit 4 324 6.1E-84 T 28-03-2018 IPR005790 DNA polymerase III, delta subunit GO:0003677|GO:0006260 CO689_RS13330 62e81ac9bc8be99781897fa786f69221 324 Gene3D G3DSA:1.20.272.10 214 324 9.7E-33 T 28-03-2018 CO689_RS13330 62e81ac9bc8be99781897fa786f69221 324 SUPERFAMILY SSF48019 205 324 7.82E-23 T 28-03-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 CO689_RS13330 62e81ac9bc8be99781897fa786f69221 324 Gene3D G3DSA:1.10.8.60 135 213 3.6E-22 T 28-03-2018 CO689_RS13330 62e81ac9bc8be99781897fa786f69221 324 Gene3D G3DSA:3.40.50.300 3 132 4.4E-15 T 28-03-2018 CO689_RS08475 f75110d652870f1356a1fb5bbad5ea29 132 Pfam PF10057 Uncharacterized conserved protein (DUF2294) 15 128 6.9E-34 T 28-03-2018 IPR018745 Domain of unknown function DUF2294 CO689_RS05535 8df35285ca959ac17adedb15965093f8 227 TIGRFAM TIGR04306 salvage_TenA: thiaminase II 13 217 1.3E-62 T 28-03-2018 IPR027574 Thiaminase II GO:0006772|GO:0050334 KEGG: 00730+3.5.99.2|MetaCyc: PWY-6899|MetaCyc: PWY-7356 CO689_RS05535 8df35285ca959ac17adedb15965093f8 227 SUPERFAMILY SSF48613 4 216 1.63E-67 T 28-03-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 CO689_RS05535 8df35285ca959ac17adedb15965093f8 227 Gene3D G3DSA:1.20.910.10 2 226 1.9E-59 T 28-03-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 CO689_RS05535 8df35285ca959ac17adedb15965093f8 227 Pfam PF03070 TENA/THI-4/PQQC family 11 217 1.5E-54 T 28-03-2018 IPR004305 Thiaminase-2/PQQC CO689_RS13815 ed57e2da049628cd501974fbd2418fbe 238 Pfam PF00072 Response regulator receiver domain 5 114 9.6E-30 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CO689_RS13815 ed57e2da049628cd501974fbd2418fbe 238 SUPERFAMILY SSF46894 131 232 1.25E-31 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CO689_RS13815 ed57e2da049628cd501974fbd2418fbe 238 Gene3D G3DSA:3.40.50.2300 1 129 9.5E-39 T 28-03-2018 CO689_RS13815 ed57e2da049628cd501974fbd2418fbe 238 Pfam PF00486 Transcriptional regulatory protein, C terminal 158 231 1.9E-29 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CO689_RS13815 ed57e2da049628cd501974fbd2418fbe 238 SMART SM00448 3 114 4.0E-46 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CO689_RS13815 ed57e2da049628cd501974fbd2418fbe 238 Gene3D G3DSA:1.10.10.10 130 238 4.2E-33 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS13815 ed57e2da049628cd501974fbd2418fbe 238 SUPERFAMILY SSF52172 2 129 1.32E-43 T 28-03-2018 IPR011006 CheY-like superfamily CO689_RS13815 ed57e2da049628cd501974fbd2418fbe 238 SMART SM00862 155 231 2.1E-30 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CO689_RS08280 71f984fdcce4ee544503fd1d6b880806 249 Gene3D G3DSA:3.30.70.1030 4 137 6.3E-38 T 28-03-2018 CO689_RS08280 71f984fdcce4ee544503fd1d6b880806 249 SUPERFAMILY SSF54909 2 248 8.04E-92 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel CO689_RS08280 71f984fdcce4ee544503fd1d6b880806 249 Hamap MF_01442 Putative heme-dependent peroxidase . 1 249 54.125 T 28-03-2018 IPR031332 Putative heme-dependent peroxidase, UPF0447 family CO689_RS08280 71f984fdcce4ee544503fd1d6b880806 249 Pfam PF06778 Chlorite dismutase 33 237 6.6E-78 T 28-03-2018 IPR010644 Putative heme-dependent peroxidase/Chlorite dismutase CO689_RS08280 71f984fdcce4ee544503fd1d6b880806 249 Gene3D G3DSA:3.30.70.1100 140 245 7.6E-31 T 28-03-2018 CO689_RS13695 ae918c8bd9689f5f46bcaa34a6035815 429 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 236 272 - T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CO689_RS13695 ae918c8bd9689f5f46bcaa34a6035815 429 Gene3D G3DSA:3.40.640.10 181 314 3.7E-42 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CO689_RS13695 ae918c8bd9689f5f46bcaa34a6035815 429 Hamap MF_00375 Glutamate-1-semialdehyde 2,1-aminomutase [hemL]. 5 426 99.666 T 28-03-2018 IPR004639 Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase GO:0033014|GO:0042286 KEGG: 00860+5.4.3.8|MetaCyc: PWY-5188 CO689_RS13695 ae918c8bd9689f5f46bcaa34a6035815 429 Gene3D G3DSA:3.90.1150.10 315 428 3.7E-17 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CO689_RS13695 ae918c8bd9689f5f46bcaa34a6035815 429 SUPERFAMILY SSF53383 1 425 2.34E-128 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CO689_RS13695 ae918c8bd9689f5f46bcaa34a6035815 429 TIGRFAM TIGR00713 hemL: glutamate-1-semialdehyde-2,1-aminomutase 5 425 1.9E-192 T 28-03-2018 IPR004639 Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase GO:0033014|GO:0042286 KEGG: 00860+5.4.3.8|MetaCyc: PWY-5188 CO689_RS13695 ae918c8bd9689f5f46bcaa34a6035815 429 Pfam PF00202 Aminotransferase class-III 32 397 4.0E-75 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CO689_RS13695 ae918c8bd9689f5f46bcaa34a6035815 429 Gene3D G3DSA:3.90.1150.10 1 180 1.2E-39 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CO689_RS01450 9e3f2a71450d975d35312b9596294e00 491 Gene3D G3DSA:3.40.190.10 39 157 3.1E-34 T 28-03-2018 CO689_RS01450 9e3f2a71450d975d35312b9596294e00 491 Gene3D G3DSA:1.10.3720.10 280 489 5.0E-45 T 28-03-2018 CO689_RS01450 9e3f2a71450d975d35312b9596294e00 491 SMART SM00079 48 267 0.0095 T 28-03-2018 IPR001320 Ionotropic glutamate receptor GO:0004970|GO:0016020 CO689_RS01450 9e3f2a71450d975d35312b9596294e00 491 SUPERFAMILY SSF53850 38 264 5.43E-60 T 28-03-2018 CO689_RS01450 9e3f2a71450d975d35312b9596294e00 491 Gene3D G3DSA:3.40.190.10 158 229 5.8E-14 T 28-03-2018 CO689_RS01450 9e3f2a71450d975d35312b9596294e00 491 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 49 259 1.2E-53 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CO689_RS01450 9e3f2a71450d975d35312b9596294e00 491 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 305 488 3.8E-23 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CO689_RS01450 9e3f2a71450d975d35312b9596294e00 491 ProSitePatterns PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 74 87 - T 28-03-2018 IPR018313 Solute-binding protein family 3, conserved site GO:0005215|GO:0006810 CO689_RS01450 9e3f2a71450d975d35312b9596294e00 491 SMART SM00062 48 269 1.6E-47 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CO689_RS01450 9e3f2a71450d975d35312b9596294e00 491 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 286 382 5.5E-27 T 28-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 CO689_RS01450 9e3f2a71450d975d35312b9596294e00 491 SUPERFAMILY SSF161098 285 476 3.27E-47 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CO689_RS03285 65e25092a196b9529eaffd3f5ec12887 77 TIGRFAM TIGR01682 moaD: molybdopterin converting factor, subunit 1 1 77 2.6E-23 T 28-03-2018 IPR010034 Molybdopterin converting factor, subunit 1 GO:0006777 Reactome: R-HSA-947581 CO689_RS03285 65e25092a196b9529eaffd3f5ec12887 77 SUPERFAMILY SSF54285 1 77 1.85E-16 T 28-03-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp CO689_RS03285 65e25092a196b9529eaffd3f5ec12887 77 Gene3D G3DSA:3.10.20.30 1 77 8.3E-19 T 28-03-2018 IPR012675 Beta-grasp domain CO689_RS03285 65e25092a196b9529eaffd3f5ec12887 77 Pfam PF02597 ThiS family 3 77 9.9E-18 T 28-03-2018 IPR003749 ThiamineS/Molybdopterin converting factor subunit 1 Reactome: R-HSA-947581 CO689_RS08000 7e59b6ea67a426919a76405776daf8ae 191 Gene3D G3DSA:1.10.1740.10 1 124 5.0E-9 T 28-03-2018 CO689_RS08000 7e59b6ea67a426919a76405776daf8ae 191 Pfam PF08281 Sigma-70, region 4 131 182 9.9E-9 T 28-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CO689_RS08000 7e59b6ea67a426919a76405776daf8ae 191 Pfam PF04542 Sigma-70 region 2 33 97 2.4E-4 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CO689_RS08000 7e59b6ea67a426919a76405776daf8ae 191 SUPERFAMILY SSF88659 130 187 2.62E-9 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CO689_RS08000 7e59b6ea67a426919a76405776daf8ae 191 SUPERFAMILY SSF88946 8 110 1.05E-12 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CO689_RS08000 7e59b6ea67a426919a76405776daf8ae 191 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 23 184 1.5E-16 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CO689_RS08000 7e59b6ea67a426919a76405776daf8ae 191 Gene3D G3DSA:1.10.10.10 125 191 5.4E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS13550 8ecd8b93957c1f3cb8fa4652277d1b90 201 SUPERFAMILY SSF50249 2 62 1.88E-16 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CO689_RS13550 8ecd8b93957c1f3cb8fa4652277d1b90 201 Pfam PF07499 RuvA, C-terminal domain 155 199 3.8E-11 T 28-03-2018 IPR011114 Holliday junction DNA helicase RuvA, C-terminal GO:0005524|GO:0006281|GO:0006310|GO:0009378|GO:0009379 CO689_RS13550 8ecd8b93957c1f3cb8fa4652277d1b90 201 Gene3D G3DSA:1.10.8.10 140 200 3.2E-8 T 28-03-2018 CO689_RS13550 8ecd8b93957c1f3cb8fa4652277d1b90 201 Gene3D G3DSA:1.10.150.280 56 79 0.01 T 28-03-2018 CO689_RS13550 8ecd8b93957c1f3cb8fa4652277d1b90 201 Gene3D G3DSA:1.10.150.20 80 117 1.9E-14 T 28-03-2018 CO689_RS13550 8ecd8b93957c1f3cb8fa4652277d1b90 201 Pfam PF14520 Helix-hairpin-helix domain 71 128 1.2E-13 T 28-03-2018 CO689_RS13550 8ecd8b93957c1f3cb8fa4652277d1b90 201 SMART SM00278 72 91 2.5 T 28-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 CO689_RS13550 8ecd8b93957c1f3cb8fa4652277d1b90 201 SMART SM00278 107 126 0.2 T 28-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 CO689_RS13550 8ecd8b93957c1f3cb8fa4652277d1b90 201 TIGRFAM TIGR00084 ruvA: Holliday junction DNA helicase RuvA 4 199 5.9E-50 T 28-03-2018 IPR000085 Bacterial DNA recombination protein RuvA GO:0003678|GO:0006281|GO:0006310 CO689_RS13550 8ecd8b93957c1f3cb8fa4652277d1b90 201 SUPERFAMILY SSF47781 64 131 3.67E-19 T 28-03-2018 IPR010994 RuvA domain 2-like CO689_RS13550 8ecd8b93957c1f3cb8fa4652277d1b90 201 Hamap MF_00031 Holliday junction ATP-dependent DNA helicase RuvA [ruvA]. 1 200 29.255 T 28-03-2018 IPR000085 Bacterial DNA recombination protein RuvA GO:0003678|GO:0006281|GO:0006310 CO689_RS13550 8ecd8b93957c1f3cb8fa4652277d1b90 201 Gene3D G3DSA:2.40.50.140 2 55 2.1E-20 T 28-03-2018 CO689_RS13550 8ecd8b93957c1f3cb8fa4652277d1b90 201 Gene3D G3DSA:1.10.150.20 118 139 0.081 T 28-03-2018 CO689_RS13550 8ecd8b93957c1f3cb8fa4652277d1b90 201 SUPERFAMILY SSF46929 153 199 7.85E-8 T 28-03-2018 IPR011114 Holliday junction DNA helicase RuvA, C-terminal GO:0005524|GO:0006281|GO:0006310|GO:0009378|GO:0009379 CO689_RS13550 8ecd8b93957c1f3cb8fa4652277d1b90 201 Pfam PF01330 RuvA N terminal domain 2 61 1.1E-19 T 28-03-2018 IPR013849 DNA helicase, Holliday junction RuvA type, domain I, bacterial GO:0005524|GO:0006281|GO:0006310|GO:0009378 CO689_RS03585 6d2e4a22932e3bccb3ac12f3d2a1744d 210 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 142 162 6.1E-6 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CO689_RS03585 6d2e4a22932e3bccb3ac12f3d2a1744d 210 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 3 14 6.1E-6 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CO689_RS03585 6d2e4a22932e3bccb3ac12f3d2a1744d 210 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 124 140 6.1E-6 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CO689_RS03585 6d2e4a22932e3bccb3ac12f3d2a1744d 210 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 93 106 6.1E-6 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CO689_RS03585 6d2e4a22932e3bccb3ac12f3d2a1744d 210 Gene3D G3DSA:3.40.50.1000 1 195 2.9E-32 T 28-03-2018 IPR023214 HAD-like domain CO689_RS03585 6d2e4a22932e3bccb3ac12f3d2a1744d 210 Pfam PF13419 Haloacid dehalogenase-like hydrolase 6 178 2.8E-33 T 28-03-2018 IPR023214 HAD-like domain CO689_RS03585 6d2e4a22932e3bccb3ac12f3d2a1744d 210 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 52 179 2.7E-12 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CO689_RS03585 6d2e4a22932e3bccb3ac12f3d2a1744d 210 SUPERFAMILY SSF56784 3 190 9.72E-40 T 28-03-2018 IPR023214 HAD-like domain CO689_RS12000 58de357b345f1ffab1a2723b8a3623b5 71 SUPERFAMILY SSF50182 7 64 6.55E-17 T 28-03-2018 IPR010920 LSM domain CO689_RS12000 58de357b345f1ffab1a2723b8a3623b5 71 Pfam PF17209 Hfq protein 7 66 6.0E-22 T 28-03-2018 IPR005001 RNA-binding protein Hfq GO:0003723|GO:0006355 CO689_RS12000 58de357b345f1ffab1a2723b8a3623b5 71 Gene3D G3DSA:2.30.30.100 5 69 2.5E-23 T 28-03-2018 CO689_RS12000 58de357b345f1ffab1a2723b8a3623b5 71 TIGRFAM TIGR02383 Hfq: RNA chaperone Hfq 6 64 8.6E-24 T 28-03-2018 IPR005001 RNA-binding protein Hfq GO:0003723|GO:0006355 CO689_RS10950 8675bfe08a91286e7715f54f1fb1fec4 160 ProDom PD094668 YLAL SIMILAR MW0994 BH2628 SE0810 SA0960 1 159 2.0E-71 T 28-03-2018 IPR020229 Uncharacterised protein YlaL CO689_RS11020 1af7c5836daeae7a0bfc1b04aaf7bd79 316 Pfam PF02423 Ornithine cyclodeaminase/mu-crystallin family 2 315 3.3E-65 T 28-03-2018 IPR003462 Ornithine cyclodeaminase/mu-crystallin Reactome: R-HSA-71064 CO689_RS11020 1af7c5836daeae7a0bfc1b04aaf7bd79 316 PIRSF PIRSF001439 1 316 3.3E-74 T 28-03-2018 IPR003462 Ornithine cyclodeaminase/mu-crystallin Reactome: R-HSA-71064 CO689_RS11020 1af7c5836daeae7a0bfc1b04aaf7bd79 316 SUPERFAMILY SSF51735 1 314 9.62E-78 T 28-03-2018 IPR016040 NAD(P)-binding domain CO689_RS11020 1af7c5836daeae7a0bfc1b04aaf7bd79 316 Gene3D G3DSA:3.30.1780.10 1 132 1.5E-30 T 28-03-2018 IPR023401 Ornithine cyclodeaminase, N-terminal Reactome: R-HSA-71064 CO689_RS11020 1af7c5836daeae7a0bfc1b04aaf7bd79 316 Gene3D G3DSA:3.40.50.720 133 298 1.6E-32 T 28-03-2018 CO689_RS11380 3f4afbf0ab78f1fca3f770ad38ee251b 133 PIRSF PIRSF021700 1 133 4.2E-35 T 28-03-2018 IPR009725 Predicted 3-demethylubiquinone-9 3-methyltransferase CO689_RS11380 3f4afbf0ab78f1fca3f770ad38ee251b 133 SUPERFAMILY SSF54593 3 131 2.07E-30 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CO689_RS11380 3f4afbf0ab78f1fca3f770ad38ee251b 133 Gene3D G3DSA:3.10.180.10 1 133 1.3E-20 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CO689_RS11380 3f4afbf0ab78f1fca3f770ad38ee251b 133 Pfam PF06983 3-demethylubiquinone-9 3-methyltransferase 5 129 3.8E-31 T 28-03-2018 IPR028973 PhnB-like CO689_RS09270 f088bad29c34c8d92104c5b1098a31b5 97 Gene3D G3DSA:3.40.1800.10 9 87 1.1E-4 T 28-03-2018 CO689_RS10335 4f1799058b25f37798a6874cf941e78d 520 Pfam PF03144 Elongation factor Tu domain 2 308 373 2.7E-12 T 28-03-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 CO689_RS10335 4f1799058b25f37798a6874cf941e78d 520 Gene3D G3DSA:2.40.30.10 264 377 1.5E-18 T 28-03-2018 CO689_RS10335 4f1799058b25f37798a6874cf941e78d 520 SUPERFAMILY SSF50447 255 380 3.53E-25 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain CO689_RS10335 4f1799058b25f37798a6874cf941e78d 520 SUPERFAMILY SSF54980 388 459 1.15E-17 T 28-03-2018 IPR035647 EF-G domain III/V-like CO689_RS10335 4f1799058b25f37798a6874cf941e78d 520 Pfam PF00009 Elongation factor Tu GTP binding domain 12 270 3.0E-54 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CO689_RS10335 4f1799058b25f37798a6874cf941e78d 520 Gene3D G3DSA:3.30.70.870 388 460 1.5E-13 T 28-03-2018 CO689_RS10335 4f1799058b25f37798a6874cf941e78d 520 PRINTS PR00315 GTP-binding elongation factor signature 98 109 1.9E-11 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CO689_RS10335 4f1799058b25f37798a6874cf941e78d 520 PRINTS PR00315 GTP-binding elongation factor signature 134 143 1.9E-11 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CO689_RS10335 4f1799058b25f37798a6874cf941e78d 520 PRINTS PR00315 GTP-binding elongation factor signature 62 70 1.9E-11 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CO689_RS10335 4f1799058b25f37798a6874cf941e78d 520 PRINTS PR00315 GTP-binding elongation factor signature 12 25 1.9E-11 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CO689_RS10335 4f1799058b25f37798a6874cf941e78d 520 PRINTS PR00315 GTP-binding elongation factor signature 82 92 1.9E-11 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CO689_RS10335 4f1799058b25f37798a6874cf941e78d 520 SUPERFAMILY SSF52540 7 270 5.54E-88 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CO689_RS10335 4f1799058b25f37798a6874cf941e78d 520 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 13 146 2.5E-23 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 CO689_RS10335 4f1799058b25f37798a6874cf941e78d 520 Gene3D G3DSA:3.40.50.300 4 263 1.2E-39 T 28-03-2018 CO689_RS10335 4f1799058b25f37798a6874cf941e78d 520 Hamap MF_00072 Peptide chain release factor 3 [prfC]. 1 520 49.126 T 28-03-2018 IPR004548 Peptide chain release factor 3 GO:0003924|GO:0005737|GO:0006415 CO689_RS10335 4f1799058b25f37798a6874cf941e78d 520 Pfam PF16658 Class II release factor RF3, C-terminal domain 382 507 1.1E-44 T 28-03-2018 IPR032090 Peptide chain release factor 3, C-terminal CO689_RS10335 4f1799058b25f37798a6874cf941e78d 520 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 55 70 - T 28-03-2018 IPR031157 Tr-type G domain, conserved site CO689_RS10335 4f1799058b25f37798a6874cf941e78d 520 TIGRFAM TIGR00503 prfC: peptide chain release factor 3 5 518 7.9E-193 T 28-03-2018 IPR004548 Peptide chain release factor 3 GO:0003924|GO:0005737|GO:0006415 CO689_RS04045 fed253f69772de29eadf5c71f7b7219a 260 SUPERFAMILY SSF53850 1 256 2.6E-65 T 28-03-2018 CO689_RS04045 fed253f69772de29eadf5c71f7b7219a 260 Gene3D G3DSA:3.40.190.10 142 248 2.7E-20 T 28-03-2018 CO689_RS04045 fed253f69772de29eadf5c71f7b7219a 260 SMART SM00062 36 256 1.1E-70 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CO689_RS04045 fed253f69772de29eadf5c71f7b7219a 260 ProSitePatterns PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 59 72 - T 28-03-2018 IPR018313 Solute-binding protein family 3, conserved site GO:0005215|GO:0006810 CO689_RS04045 fed253f69772de29eadf5c71f7b7219a 260 SMART SM00079 36 255 3.4E-4 T 28-03-2018 IPR001320 Ionotropic glutamate receptor GO:0004970|GO:0016020 CO689_RS04045 fed253f69772de29eadf5c71f7b7219a 260 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 38 255 1.5E-59 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CO689_RS04045 fed253f69772de29eadf5c71f7b7219a 260 Gene3D G3DSA:3.40.190.10 29 141 6.8E-36 T 28-03-2018 CO689_RS08965 f7e3cbb05214cab157ff44d74983120a 500 ProSitePatterns PS01023 PTR2 family proton/oligopeptide symporters signature 2. 158 170 - T 28-03-2018 IPR018456 PTR2 family proton/oligopeptide symporter, conserved site GO:0005215|GO:0006857|GO:0016020 Reactome: R-HSA-427975 CO689_RS08965 f7e3cbb05214cab157ff44d74983120a 500 SUPERFAMILY SSF103473 280 492 1.7E-27 T 28-03-2018 IPR020846 Major facilitator superfamily domain CO689_RS08965 f7e3cbb05214cab157ff44d74983120a 500 SUPERFAMILY SSF103473 12 210 1.7E-27 T 28-03-2018 IPR020846 Major facilitator superfamily domain CO689_RS08965 f7e3cbb05214cab157ff44d74983120a 500 Gene3D G3DSA:1.20.1250.20 288 494 1.3E-16 T 28-03-2018 CO689_RS08965 f7e3cbb05214cab157ff44d74983120a 500 Pfam PF00854 POT family 96 463 1.8E-61 T 28-03-2018 IPR000109 Proton-dependent oligopeptide transporter family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-427975 CO689_RS08965 f7e3cbb05214cab157ff44d74983120a 500 TIGRFAM TIGR00924 yjdL_sub1_fam: amino acid/peptide transporter (Peptide:H+ symporter) 16 494 6.3E-108 T 28-03-2018 IPR005279 Dipeptide/tripeptide permease GO:0015197|GO:0015833|GO:0016020 CO689_RS08965 f7e3cbb05214cab157ff44d74983120a 500 Gene3D G3DSA:1.20.1250.20 9 223 1.3E-19 T 28-03-2018 CO689_RS11465 bd1cf99ab158a570fd4c6e042cee891c 664 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 129 141 - T 28-03-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 CO689_RS11465 bd1cf99ab158a570fd4c6e042cee891c 664 Gene3D G3DSA:3.30.200.20 2 77 1.1E-21 T 28-03-2018 CO689_RS11465 bd1cf99ab158a570fd4c6e042cee891c 664 SUPERFAMILY SSF56112 8 263 3.37E-82 T 28-03-2018 IPR011009 Protein kinase-like domain CO689_RS11465 bd1cf99ab158a570fd4c6e042cee891c 664 SMART SM00220 10 267 1.6E-72 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CO689_RS11465 bd1cf99ab158a570fd4c6e042cee891c 664 Pfam PF00069 Protein kinase domain 10 257 1.2E-57 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CO689_RS11465 bd1cf99ab158a570fd4c6e042cee891c 664 SMART SM00740 365 432 4.6E-17 T 28-03-2018 IPR005543 PASTA domain CO689_RS11465 bd1cf99ab158a570fd4c6e042cee891c 664 SMART SM00740 433 502 2.4E-8 T 28-03-2018 IPR005543 PASTA domain CO689_RS11465 bd1cf99ab158a570fd4c6e042cee891c 664 SMART SM00740 503 569 2.0E-16 T 28-03-2018 IPR005543 PASTA domain CO689_RS11465 bd1cf99ab158a570fd4c6e042cee891c 664 Gene3D G3DSA:1.10.510.10 78 527 9.8E-58 T 28-03-2018 CO689_RS11465 bd1cf99ab158a570fd4c6e042cee891c 664 Pfam PF03793 PASTA domain 370 432 1.3E-12 T 28-03-2018 IPR005543 PASTA domain CO689_RS11465 bd1cf99ab158a570fd4c6e042cee891c 664 Pfam PF03793 PASTA domain 507 568 2.1E-14 T 28-03-2018 IPR005543 PASTA domain CO689_RS11465 bd1cf99ab158a570fd4c6e042cee891c 664 Pfam PF03793 PASTA domain 438 499 4.0E-7 T 28-03-2018 IPR005543 PASTA domain CO689_RS11465 bd1cf99ab158a570fd4c6e042cee891c 664 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 16 39 - T 28-03-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 CO689_RS00940 46c3acef4f315e5d0661749874f260ff 420 Pfam PF01479 S4 domain 356 400 8.9E-10 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CO689_RS00940 46c3acef4f315e5d0661749874f260ff 420 Gene3D G3DSA:3.10.290.10 326 420 5.6E-23 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CO689_RS00940 46c3acef4f315e5d0661749874f260ff 420 Gene3D G3DSA:3.40.50.620 2 224 7.8E-71 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CO689_RS00940 46c3acef4f315e5d0661749874f260ff 420 SUPERFAMILY SSF52374 2 324 8.45E-109 T 28-03-2018 CO689_RS00940 46c3acef4f315e5d0661749874f260ff 420 Hamap MF_02006 Tyrosine--tRNA ligase [tyrS]. 3 419 44.947 T 28-03-2018 IPR024107 Tyrosine-tRNA ligase, bacterial-type, type 1 GO:0004831 KEGG: 00970+6.1.1.1 CO689_RS00940 46c3acef4f315e5d0661749874f260ff 420 SUPERFAMILY SSF55174 322 419 1.44E-23 T 28-03-2018 CO689_RS00940 46c3acef4f315e5d0661749874f260ff 420 SMART SM00363 353 415 8.9E-7 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CO689_RS00940 46c3acef4f315e5d0661749874f260ff 420 Gene3D G3DSA:1.10.240.10 225 325 5.4E-35 T 28-03-2018 CO689_RS00940 46c3acef4f315e5d0661749874f260ff 420 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 183 205 2.9E-30 T 28-03-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 CO689_RS00940 46c3acef4f315e5d0661749874f260ff 420 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 162 177 2.9E-30 T 28-03-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 CO689_RS00940 46c3acef4f315e5d0661749874f260ff 420 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 217 229 2.9E-30 T 28-03-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 CO689_RS00940 46c3acef4f315e5d0661749874f260ff 420 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 45 67 2.9E-30 T 28-03-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 CO689_RS00940 46c3acef4f315e5d0661749874f260ff 420 TIGRFAM TIGR00234 tyrS: tyrosine--tRNA ligase 2 419 4.1E-134 T 28-03-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 CO689_RS00940 46c3acef4f315e5d0661749874f260ff 420 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 41 51 - T 28-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 CO689_RS00940 46c3acef4f315e5d0661749874f260ff 420 Pfam PF00579 tRNA synthetases class I (W and Y) 30 324 1.2E-83 T 28-03-2018 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 CO689_RS02565 6974efbdd48df7eac5a55de84308fd0c 538 SUPERFAMILY SSF52317 291 535 1.67E-84 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CO689_RS02565 6974efbdd48df7eac5a55de84308fd0c 538 Gene3D G3DSA:3.40.50.300 1 287 5.2E-131 T 28-03-2018 CO689_RS02565 6974efbdd48df7eac5a55de84308fd0c 538 Pfam PF06418 CTP synthase N-terminus 3 267 1.4E-127 T 28-03-2018 IPR017456 CTP synthase, N-terminal GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 CO689_RS02565 6974efbdd48df7eac5a55de84308fd0c 538 SUPERFAMILY SSF52540 1 269 1.13E-124 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CO689_RS02565 6974efbdd48df7eac5a55de84308fd0c 538 Pfam PF00117 Glutamine amidotransferase class-I 303 528 8.9E-56 T 28-03-2018 IPR017926 Glutamine amidotransferase CO689_RS02565 6974efbdd48df7eac5a55de84308fd0c 538 TIGRFAM TIGR00337 PyrG: CTP synthase 1 528 4.2E-254 T 28-03-2018 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 CO689_RS02565 6974efbdd48df7eac5a55de84308fd0c 538 Gene3D G3DSA:3.40.50.880 288 536 1.2E-75 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CO689_RS02565 6974efbdd48df7eac5a55de84308fd0c 538 Hamap MF_01227 CTP synthase [pyrG]. 2 533 52.788 T 28-03-2018 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 CO689_RS02290 4c077989ffb2b737031b6814b134e914 117 TIGRFAM TIGR00556 pantethn_trn: phosphopantetheine--protein transferase domain 2 116 1.1E-29 T 28-03-2018 IPR004568 Phosphopantetheine-protein transferase domain GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 CO689_RS02290 4c077989ffb2b737031b6814b134e914 117 Gene3D G3DSA:3.90.470.20 1 117 7.2E-35 T 28-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 CO689_RS02290 4c077989ffb2b737031b6814b134e914 117 Pfam PF01648 4'-phosphopantetheinyl transferase superfamily 4 108 1.5E-20 T 28-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 CO689_RS02290 4c077989ffb2b737031b6814b134e914 117 ProDom PD004282 TRANSFERASE SYNTHASE HOLO-ACYL-CARRIER-PROTEIN HOLO-ACP 4'-PHOSPHOPANTETHEINYL FATTY ACID METAL-BINDING MAGNESIUM LIPID 8 115 1.0E-36 T 28-03-2018 IPR004568 Phosphopantetheine-protein transferase domain GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 CO689_RS02290 4c077989ffb2b737031b6814b134e914 117 TIGRFAM TIGR00516 acpS: holo-[acyl-carrier-protein] synthase 1 116 6.5E-37 T 28-03-2018 IPR002582 Holo-[acyl carrier protein] synthase GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 CO689_RS02290 4c077989ffb2b737031b6814b134e914 117 Hamap MF_00101 Holo-[acyl-carrier-protein] synthase [acpS]. 3 116 24.62 T 28-03-2018 IPR002582 Holo-[acyl carrier protein] synthase GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 CO689_RS02290 4c077989ffb2b737031b6814b134e914 117 SUPERFAMILY SSF56214 2 115 3.27E-32 T 28-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 CO689_RS07315 b8a7ab91f92b1da83a45cd2db18ce089 199 Pfam PF01583 Adenylylsulphate kinase 26 181 2.5E-74 T 28-03-2018 CO689_RS07315 b8a7ab91f92b1da83a45cd2db18ce089 199 SUPERFAMILY SSF52540 24 195 1.26E-40 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CO689_RS07315 b8a7ab91f92b1da83a45cd2db18ce089 199 Hamap MF_00065 Adenylyl-sulfate kinase [cysC]. 25 197 38.676 T 28-03-2018 IPR002891 Adenylyl-sulfate kinase GO:0000103|GO:0004020|GO:0005524 KEGG: 00230+2.7.1.25|KEGG: 00920+2.7.1.25|MetaCyc: PWY-5340|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 CO689_RS07315 b8a7ab91f92b1da83a45cd2db18ce089 199 TIGRFAM TIGR00455 apsK: adenylyl-sulfate kinase 9 193 8.8E-86 T 28-03-2018 IPR002891 Adenylyl-sulfate kinase GO:0000103|GO:0004020|GO:0005524 KEGG: 00230+2.7.1.25|KEGG: 00920+2.7.1.25|MetaCyc: PWY-5340|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 CO689_RS07315 b8a7ab91f92b1da83a45cd2db18ce089 199 Gene3D G3DSA:3.40.50.300 22 199 2.4E-56 T 28-03-2018 CO689_RS09515 c58a0e87e5a5515321e7a9b7882d7f48 156 Gene3D G3DSA:3.90.1010.10 3 140 1.6E-52 T 28-03-2018 CO689_RS09515 c58a0e87e5a5515321e7a9b7882d7f48 156 SUPERFAMILY SSF82649 3 138 2.49E-50 T 28-03-2018 CO689_RS09515 c58a0e87e5a5515321e7a9b7882d7f48 156 TIGRFAM TIGR01994 SUF_scaf_2: SUF system FeS assembly protein, NifU family 6 138 9.4E-55 T 28-03-2018 CO689_RS09515 c58a0e87e5a5515321e7a9b7882d7f48 156 Pfam PF01592 NifU-like N terminal domain 10 128 1.9E-32 T 28-03-2018 IPR002871 NIF system FeS cluster assembly, NifU, N-terminal GO:0005506|GO:0016226|GO:0051536 Reactome: R-HSA-1362409 CO689_RS00605 a86d44db9e1679547b6bf35b620cadba 88 Gene3D G3DSA:1.10.10.10 1 86 3.6E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS00605 a86d44db9e1679547b6bf35b620cadba 88 Pfam PF01638 HxlR-like helix-turn-helix 2 83 1.4E-23 T 28-03-2018 IPR002577 Helix-turn-helix, HxlR type CO689_RS00605 a86d44db9e1679547b6bf35b620cadba 88 SUPERFAMILY SSF46785 2 80 1.05E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS04010 3c01ef448be927219376cf62ceb952cb 171 SMART SM00867 3 168 4.7E-54 T 28-03-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like CO689_RS04010 3c01ef448be927219376cf62ceb952cb 171 Gene3D G3DSA:2.40.128.110 1 171 6.7E-44 T 28-03-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like CO689_RS04010 3c01ef448be927219376cf62ceb952cb 171 SUPERFAMILY SSF101874 3 168 2.75E-45 T 28-03-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like CO689_RS04010 3c01ef448be927219376cf62ceb952cb 171 Pfam PF04264 YceI-like domain 4 167 7.2E-39 T 28-03-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like CO689_RS01115 f9ebe1b579f1e5017ed5eac1cca2ca73 393 Pfam PF00925 GTP cyclohydrolase II 209 368 1.7E-64 T 28-03-2018 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 CO689_RS01115 f9ebe1b579f1e5017ed5eac1cca2ca73 393 SUPERFAMILY SSF142695 208 371 1.96E-56 T 28-03-2018 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 CO689_RS01115 f9ebe1b579f1e5017ed5eac1cca2ca73 393 Hamap MF_00179 GTP cyclohydrolase-2 [ribA]. 203 393 35.506 T 28-03-2018 IPR000926 GTP cyclohydrolase II, RibA GO:0003935|GO:0009231 KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 CO689_RS01115 f9ebe1b579f1e5017ed5eac1cca2ca73 393 PIRSF PIRSF001259 1 393 5.0E-148 T 28-03-2018 CO689_RS01115 f9ebe1b579f1e5017ed5eac1cca2ca73 393 Gene3D G3DSA:3.90.870.10 1 211 6.0E-84 T 28-03-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain CO689_RS01115 f9ebe1b579f1e5017ed5eac1cca2ca73 393 Hamap MF_00180 3,4-dihydroxy-2-butanone 4-phosphate synthase [ribB]. 1 202 36.191 T 28-03-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CO689_RS01115 f9ebe1b579f1e5017ed5eac1cca2ca73 393 TIGRFAM TIGR00505 ribA: GTP cyclohydrolase II 209 393 1.2E-69 T 28-03-2018 IPR000926 GTP cyclohydrolase II, RibA GO:0003935|GO:0009231 KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 CO689_RS01115 f9ebe1b579f1e5017ed5eac1cca2ca73 393 SUPERFAMILY SSF55821 2 201 8.24E-76 T 28-03-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain CO689_RS01115 f9ebe1b579f1e5017ed5eac1cca2ca73 393 Hamap MF_01283 Riboflavin biosynthesis protein RibBA [ribBA]. 2 391 50.964 T 28-03-2018 IPR016299 Riboflavin biosynthesis protein RibBA GO:0009231 KEGG: 00740+3.5.4.25+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7539 CO689_RS01115 f9ebe1b579f1e5017ed5eac1cca2ca73 393 TIGRFAM TIGR00506 ribB: 3,4-dihydroxy-2-butanone-4-phosphate synthase 3 198 3.5E-67 T 28-03-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CO689_RS01115 f9ebe1b579f1e5017ed5eac1cca2ca73 393 Pfam PF00926 3,4-dihydroxy-2-butanone 4-phosphate synthase 7 197 3.1E-76 T 28-03-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CO689_RS10930 e0bd5d2008796f8325a08c4199a9a034 272 PRINTS PR00377 Inositol monophosphatase superfamily signature 82 98 7.4E-36 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CO689_RS10930 e0bd5d2008796f8325a08c4199a9a034 272 PRINTS PR00377 Inositol monophosphatase superfamily signature 58 74 7.4E-36 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CO689_RS10930 e0bd5d2008796f8325a08c4199a9a034 272 PRINTS PR00377 Inositol monophosphatase superfamily signature 206 230 7.4E-36 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CO689_RS10930 e0bd5d2008796f8325a08c4199a9a034 272 PRINTS PR00377 Inositol monophosphatase superfamily signature 175 196 7.4E-36 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CO689_RS10930 e0bd5d2008796f8325a08c4199a9a034 272 PRINTS PR00377 Inositol monophosphatase superfamily signature 36 56 7.4E-36 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CO689_RS10930 e0bd5d2008796f8325a08c4199a9a034 272 PRINTS PR00377 Inositol monophosphatase superfamily signature 131 154 7.4E-36 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CO689_RS10930 e0bd5d2008796f8325a08c4199a9a034 272 ProSitePatterns PS00630 Inositol monophosphatase family signature 2. 209 223 - T 28-03-2018 IPR020550 Inositol monophosphatase, conserved site GO:0046854 CO689_RS10930 e0bd5d2008796f8325a08c4199a9a034 272 Gene3D G3DSA:3.30.540.10 1 150 1.0E-44 T 28-03-2018 CO689_RS10930 e0bd5d2008796f8325a08c4199a9a034 272 Gene3D G3DSA:3.40.190.80 151 271 1.3E-27 T 28-03-2018 CO689_RS10930 e0bd5d2008796f8325a08c4199a9a034 272 Pfam PF00459 Inositol monophosphatase family 3 253 4.5E-61 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CO689_RS10930 e0bd5d2008796f8325a08c4199a9a034 272 ProSitePatterns PS00629 Inositol monophosphatase family signature 1. 82 95 - T 28-03-2018 IPR020583 Inositol monophosphatase, metal-binding site CO689_RS10930 e0bd5d2008796f8325a08c4199a9a034 272 SUPERFAMILY SSF56655 3 254 6.81E-75 T 28-03-2018 CO689_RS07985 0930232172e680f9f0d11d20ea9591d6 133 SUPERFAMILY SSF69065 6 129 4.71E-41 T 28-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 CO689_RS07985 0930232172e680f9f0d11d20ea9591d6 133 Hamap MF_01468 Mini-ribonuclease 3 [mrnC]. 4 130 28.182 T 28-03-2018 IPR008226 Mini-ribonuclease 3 family CO689_RS07985 0930232172e680f9f0d11d20ea9591d6 133 Gene3D G3DSA:1.10.1520.10 1 133 3.5E-19 T 28-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 CO689_RS07985 0930232172e680f9f0d11d20ea9591d6 133 Pfam PF00636 Ribonuclease III domain 14 113 3.4E-15 T 28-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 CO689_RS07985 0930232172e680f9f0d11d20ea9591d6 133 PIRSF PIRSF005520 1 133 2.4E-51 T 28-03-2018 IPR008226 Mini-ribonuclease 3 family CO689_RS05105 62e26ec9aef3ac3e4d991281cccccfb7 98 Pfam PF04066 Multiple resistance and pH regulation protein F (MrpF / PhaF) 35 87 3.3E-15 T 28-03-2018 IPR007208 Na(+)/H(+) antiporter subunit F-like GO:0015075|GO:0016021|GO:0034220 CO689_RS05105 62e26ec9aef3ac3e4d991281cccccfb7 98 PIRSF PIRSF028784 2 96 3.9E-27 T 28-03-2018 IPR007208 Na(+)/H(+) antiporter subunit F-like GO:0015075|GO:0016021|GO:0034220 CO689_RS09025 0f5c19af4d6d2347586bf12ec69d9cd1 307 Gene3D G3DSA:3.30.43.10 16 88 1.2E-17 T 28-03-2018 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 CO689_RS09025 0f5c19af4d6d2347586bf12ec69d9cd1 307 SUPERFAMILY SSF56176 5 196 1.35E-44 T 28-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CO689_RS09025 0f5c19af4d6d2347586bf12ec69d9cd1 307 SUPERFAMILY SSF56194 198 302 4.84E-38 T 28-03-2018 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CO689_RS09025 0f5c19af4d6d2347586bf12ec69d9cd1 307 Gene3D G3DSA:3.30.465.10 91 217 1.8E-38 T 28-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CO689_RS09025 0f5c19af4d6d2347586bf12ec69d9cd1 307 Hamap MF_00037 UDP-N-acetylenolpyruvoylglucosamine reductase [murB]. 1 307 93.239 T 28-03-2018 IPR003170 UDP-N-acetylenolpyruvoylglucosamine reductase GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CO689_RS09025 0f5c19af4d6d2347586bf12ec69d9cd1 307 Pfam PF02873 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain 202 300 6.6E-29 T 28-03-2018 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CO689_RS09025 0f5c19af4d6d2347586bf12ec69d9cd1 307 Pfam PF01565 FAD binding domain 38 166 3.7E-23 T 28-03-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 CO689_RS09025 0f5c19af4d6d2347586bf12ec69d9cd1 307 Gene3D G3DSA:3.90.78.10 218 305 7.1E-27 T 28-03-2018 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CO689_RS09025 0f5c19af4d6d2347586bf12ec69d9cd1 307 TIGRFAM TIGR00179 murB: UDP-N-acetylenolpyruvoylglucosamine reductase 25 301 1.9E-70 T 28-03-2018 IPR003170 UDP-N-acetylenolpyruvoylglucosamine reductase GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CO689_RS05775 3d08a2ccf39ba68064e2ad7a691b62ac 527 Gene3D G3DSA:3.40.50.980 17 180 8.4E-32 T 28-03-2018 CO689_RS05775 3d08a2ccf39ba68064e2ad7a691b62ac 527 Pfam PF00501 AMP-binding enzyme 22 423 1.4E-83 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CO689_RS05775 3d08a2ccf39ba68064e2ad7a691b62ac 527 Gene3D G3DSA:3.40.50.980 181 330 2.1E-40 T 28-03-2018 CO689_RS05775 3d08a2ccf39ba68064e2ad7a691b62ac 527 ProSitePatterns PS00455 Putative AMP-binding domain signature. 175 186 - T 28-03-2018 IPR020845 AMP-binding, conserved site CO689_RS05775 3d08a2ccf39ba68064e2ad7a691b62ac 527 Gene3D G3DSA:3.30.300.30 419 527 1.1E-27 T 28-03-2018 CO689_RS05775 3d08a2ccf39ba68064e2ad7a691b62ac 527 Gene3D G3DSA:2.30.38.10 331 416 5.5E-21 T 28-03-2018 CO689_RS05775 3d08a2ccf39ba68064e2ad7a691b62ac 527 SUPERFAMILY SSF56801 22 522 1.57E-140 T 28-03-2018 CO689_RS05775 3d08a2ccf39ba68064e2ad7a691b62ac 527 Pfam PF13193 AMP-binding enzyme C-terminal domain 432 510 2.1E-22 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CO689_RS00865 aeff6b7550c4300be236bb71b7c29087 407 Hamap MF_00021 tRNA sulfurtransferase [thiI]. 1 407 156.122 T 28-03-2018 IPR003720 tRNA sulfurtransferase ThiI GO:0005737|GO:0016783|GO:0034227 CO689_RS00865 aeff6b7550c4300be236bb71b7c29087 407 Pfam PF02568 Thiamine biosynthesis protein (ThiI) 175 370 3.1E-63 T 28-03-2018 IPR020536 Thil, AANH domain GO:0004810 CO689_RS00865 aeff6b7550c4300be236bb71b7c29087 407 Gene3D G3DSA:3.30.2300.10 83 163 5.5E-17 T 28-03-2018 CO689_RS00865 aeff6b7550c4300be236bb71b7c29087 407 Gene3D G3DSA:3.40.50.620 175 403 1.3E-33 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CO689_RS00865 aeff6b7550c4300be236bb71b7c29087 407 SMART SM00981 75 165 7.3E-18 T 28-03-2018 IPR004114 THUMP domain GO:0003723 CO689_RS00865 aeff6b7550c4300be236bb71b7c29087 407 Pfam PF02926 THUMP domain 44 162 3.3E-18 T 28-03-2018 IPR004114 THUMP domain GO:0003723 CO689_RS00865 aeff6b7550c4300be236bb71b7c29087 407 SUPERFAMILY SSF143437 3 173 5.76E-48 T 28-03-2018 CO689_RS00865 aeff6b7550c4300be236bb71b7c29087 407 TIGRFAM TIGR00342 TIGR00342: tRNA sulfurtransferase ThiI 6 373 1.1E-119 T 28-03-2018 IPR003720 tRNA sulfurtransferase ThiI GO:0005737|GO:0016783|GO:0034227 CO689_RS00865 aeff6b7550c4300be236bb71b7c29087 407 Gene3D G3DSA:3.30.70.1510 5 82 2.8E-24 T 28-03-2018 CO689_RS00865 aeff6b7550c4300be236bb71b7c29087 407 SUPERFAMILY SSF52402 174 387 1.19E-51 T 28-03-2018 CO689_RS11635 58b56da69fd7852d4ef9c096766283ed 304 PRINTS PR01798 Succinyl-CoA synthase signature 208 221 4.0E-38 T 28-03-2018 CO689_RS11635 58b56da69fd7852d4ef9c096766283ed 304 PRINTS PR01798 Succinyl-CoA synthase signature 240 257 4.0E-38 T 28-03-2018 CO689_RS11635 58b56da69fd7852d4ef9c096766283ed 304 PRINTS PR01798 Succinyl-CoA synthase signature 82 99 4.0E-38 T 28-03-2018 CO689_RS11635 58b56da69fd7852d4ef9c096766283ed 304 PRINTS PR01798 Succinyl-CoA synthase signature 177 195 4.0E-38 T 28-03-2018 CO689_RS11635 58b56da69fd7852d4ef9c096766283ed 304 ProSitePatterns PS01216 ATP-citrate lyase / succinyl-CoA ligases family signature 1. 152 181 - T 28-03-2018 IPR033847 ATP-citrate lyase/succinyl-CoA ligase, conserved site CO689_RS11635 58b56da69fd7852d4ef9c096766283ed 304 Gene3D G3DSA:3.40.50.261 120 303 6.3E-54 T 28-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CO689_RS11635 58b56da69fd7852d4ef9c096766283ed 304 SUPERFAMILY SSF52210 123 285 1.31E-53 T 28-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CO689_RS11635 58b56da69fd7852d4ef9c096766283ed 304 Pfam PF00549 CoA-ligase 151 268 1.2E-17 T 28-03-2018 IPR005811 ATP-citrate lyase/succinyl-CoA ligase GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CO689_RS11635 58b56da69fd7852d4ef9c096766283ed 304 SMART SM00881 4 100 4.0E-34 T 28-03-2018 IPR003781 CoA-binding GO:0048037 CO689_RS11635 58b56da69fd7852d4ef9c096766283ed 304 TIGRFAM TIGR01019 sucCoAalpha: succinate-CoA ligase, alpha subunit 4 286 2.8E-146 T 28-03-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 CO689_RS11635 58b56da69fd7852d4ef9c096766283ed 304 Hamap MF_01988 Succinate--CoA ligase [ADP-forming] subunit alpha [sucD]. 1 288 43.001 T 28-03-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 CO689_RS11635 58b56da69fd7852d4ef9c096766283ed 304 PIRSF PIRSF001553 1 291 2.1E-134 T 28-03-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 CO689_RS11635 58b56da69fd7852d4ef9c096766283ed 304 ProSitePatterns PS00399 ATP-citrate lyase / succinyl-CoA ligases family active site. 236 249 - T 28-03-2018 IPR017440 ATP-citrate lyase/succinyl-CoA ligase, active site CO689_RS11635 58b56da69fd7852d4ef9c096766283ed 304 SUPERFAMILY SSF51735 1 122 2.96E-43 T 28-03-2018 IPR016040 NAD(P)-binding domain CO689_RS11635 58b56da69fd7852d4ef9c096766283ed 304 Gene3D G3DSA:3.40.50.720 1 119 4.1E-45 T 28-03-2018 CO689_RS11635 58b56da69fd7852d4ef9c096766283ed 304 Pfam PF02629 CoA binding domain 6 99 4.5E-31 T 28-03-2018 IPR003781 CoA-binding GO:0048037 CO689_RS13790 81581f841f015b653ca8cd811c399ef4 340 SUPERFAMILY SSF55347 153 312 9.82E-66 T 28-03-2018 CO689_RS13790 81581f841f015b653ca8cd811c399ef4 340 ProSitePatterns PS00071 Glyceraldehyde 3-phosphate dehydrogenase active site. 151 158 - T 28-03-2018 IPR020830 Glyceraldehyde 3-phosphate dehydrogenase, active site GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CO689_RS13790 81581f841f015b653ca8cd811c399ef4 340 Gene3D G3DSA:3.40.50.720 1 162 2.3E-67 T 28-03-2018 CO689_RS13790 81581f841f015b653ca8cd811c399ef4 340 SUPERFAMILY SSF51735 1 179 1.82E-55 T 28-03-2018 IPR016040 NAD(P)-binding domain CO689_RS13790 81581f841f015b653ca8cd811c399ef4 340 PIRSF PIRSF000149 1 333 6.2E-128 T 28-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CO689_RS13790 81581f841f015b653ca8cd811c399ef4 340 Pfam PF02800 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain 159 311 5.3E-64 T 28-03-2018 IPR020829 Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CO689_RS13790 81581f841f015b653ca8cd811c399ef4 340 Pfam PF00044 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 4 101 1.9E-36 T 28-03-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CO689_RS13790 81581f841f015b653ca8cd811c399ef4 340 Gene3D G3DSA:3.30.360.10 163 313 4.7E-62 T 28-03-2018 CO689_RS13790 81581f841f015b653ca8cd811c399ef4 340 SMART SM00846 3 153 1.2E-75 T 28-03-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CO689_RS13790 81581f841f015b653ca8cd811c399ef4 340 TIGRFAM TIGR01534 GAPDH-I: glyceraldehyde-3-phosphate dehydrogenase, type I 4 323 1.2E-125 T 28-03-2018 IPR006424 Glyceraldehyde-3-phosphate dehydrogenase, type I GO:0006006|GO:0016620|GO:0050661|GO:0051287|GO:0055114 KEGG: 00010+1.2.1.12|KEGG: 00710+1.2.1.12|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CO689_RS13790 81581f841f015b653ca8cd811c399ef4 340 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 230 247 3.9E-38 T 28-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CO689_RS13790 81581f841f015b653ca8cd811c399ef4 340 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 267 282 3.9E-38 T 28-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CO689_RS13790 81581f841f015b653ca8cd811c399ef4 340 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 147 165 3.9E-38 T 28-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CO689_RS13790 81581f841f015b653ca8cd811c399ef4 340 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 109 122 3.9E-38 T 28-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CO689_RS13790 81581f841f015b653ca8cd811c399ef4 340 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 174 190 3.9E-38 T 28-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CO689_RS09320 3c6f298d297a5e110644e3ad8beebdf6 341 Gene3D G3DSA:3.40.50.1360 95 341 7.1E-33 T 28-03-2018 CO689_RS09320 3c6f298d297a5e110644e3ad8beebdf6 341 SUPERFAMILY SSF100950 96 336 8.04E-65 T 28-03-2018 CO689_RS09320 3c6f298d297a5e110644e3ad8beebdf6 341 SUPERFAMILY SSF46785 19 84 1.09E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS09320 3c6f298d297a5e110644e3ad8beebdf6 341 Pfam PF04198 Putative sugar-binding domain 94 336 1.2E-66 T 28-03-2018 IPR007324 Sugar-binding domain, putative GO:0030246 CO689_RS09320 3c6f298d297a5e110644e3ad8beebdf6 341 Gene3D G3DSA:1.10.10.10 18 87 3.9E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS12440 493bd4f37a4a3f88a7071cac3e14a752 533 Gene3D G3DSA:3.40.50.300 1 283 7.5E-56 T 28-03-2018 CO689_RS12440 493bd4f37a4a3f88a7071cac3e14a752 533 Pfam PF00005 ABC transporter 335 469 6.5E-18 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CO689_RS12440 493bd4f37a4a3f88a7071cac3e14a752 533 Pfam PF00005 ABC transporter 18 184 8.1E-21 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CO689_RS12440 493bd4f37a4a3f88a7071cac3e14a752 533 Pfam PF12848 ABC transporter 224 305 3.3E-21 T 28-03-2018 IPR032781 ABC-transporter extension domain CO689_RS12440 493bd4f37a4a3f88a7071cac3e14a752 533 SUPERFAMILY SSF52540 296 524 1.43E-40 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CO689_RS12440 493bd4f37a4a3f88a7071cac3e14a752 533 SUPERFAMILY SSF52540 125 252 2.04E-44 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CO689_RS12440 493bd4f37a4a3f88a7071cac3e14a752 533 SUPERFAMILY SSF52540 2 92 2.04E-44 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CO689_RS12440 493bd4f37a4a3f88a7071cac3e14a752 533 Gene3D G3DSA:3.40.50.300 284 532 5.1E-44 T 28-03-2018 CO689_RS12440 493bd4f37a4a3f88a7071cac3e14a752 533 SMART SM00382 26 238 8.9E-9 T 28-03-2018 IPR003593 AAA+ ATPase domain CO689_RS12440 493bd4f37a4a3f88a7071cac3e14a752 533 SMART SM00382 344 514 4.2E-7 T 28-03-2018 IPR003593 AAA+ ATPase domain CO689_RS08990 c0651c4db4b3c3ab16f897a52af3731f 701 Pfam PF02867 Ribonucleotide reductase, barrel domain 169 685 4.3E-136 T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CO689_RS08990 c0651c4db4b3c3ab16f897a52af3731f 701 SUPERFAMILY SSF48168 10 167 1.57E-41 T 28-03-2018 IPR008926 Ribonucleotide reductase R1 subunit, N-terminal KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CO689_RS08990 c0651c4db4b3c3ab16f897a52af3731f 701 Gene3D G3DSA:3.20.70.20 70 692 9.0E-151 T 28-03-2018 CO689_RS08990 c0651c4db4b3c3ab16f897a52af3731f 701 PRINTS PR01183 Ribonucleotide reductase large chain signature 377 388 4.8E-28 T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CO689_RS08990 c0651c4db4b3c3ab16f897a52af3731f 701 PRINTS PR01183 Ribonucleotide reductase large chain signature 460 482 4.8E-28 T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CO689_RS08990 c0651c4db4b3c3ab16f897a52af3731f 701 PRINTS PR01183 Ribonucleotide reductase large chain signature 244 263 4.8E-28 T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CO689_RS08990 c0651c4db4b3c3ab16f897a52af3731f 701 PRINTS PR01183 Ribonucleotide reductase large chain signature 488 511 4.8E-28 T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CO689_RS08990 c0651c4db4b3c3ab16f897a52af3731f 701 PRINTS PR01183 Ribonucleotide reductase large chain signature 570 597 4.8E-28 T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CO689_RS08990 c0651c4db4b3c3ab16f897a52af3731f 701 SUPERFAMILY SSF51998 168 688 8.85E-174 T 28-03-2018 CO689_RS08990 c0651c4db4b3c3ab16f897a52af3731f 701 Pfam PF00317 Ribonucleotide reductase, all-alpha domain 93 164 1.2E-13 T 28-03-2018 IPR013509 Ribonucleotide reductase large subunit, N-terminal GO:0004748|GO:0005524|GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CO689_RS08990 c0651c4db4b3c3ab16f897a52af3731f 701 Pfam PF08343 Ribonucleotide reductase N-terminal 11 90 1.6E-20 T 28-03-2018 IPR013554 Ribonucleotide reductase N-terminal KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CO689_RS08990 c0651c4db4b3c3ab16f897a52af3731f 701 TIGRFAM TIGR04170 RNR_1b_NrdE: ribonucleoside-diphosphate reductase, class 1b, alpha subunit 10 701 0.0 T 28-03-2018 IPR026459 Ribonucleotide reductase, class 1b, subunit NrdE KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CO689_RS08990 c0651c4db4b3c3ab16f897a52af3731f 701 ProSitePatterns PS00089 Ribonucleotide reductase large subunit signature. 559 581 - T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CO689_RS08990 c0651c4db4b3c3ab16f897a52af3731f 701 TIGRFAM TIGR02506 NrdE_NrdA: ribonucleoside-diphosphate reductase, alpha subunit 95 688 2.7E-164 T 28-03-2018 IPR013346 Ribonucleotide reductase, class I , alpha subunit GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CO689_RS09755 d461365049d9e62f4c4821852045c670 96 Pfam PF05135 Phage gp6-like head-tail connector protein 3 88 5.7E-10 T 28-03-2018 IPR021146 Phage gp6-like head-tail connector protein CO689_RS09755 d461365049d9e62f4c4821852045c670 96 TIGRFAM TIGR01560 put_DNA_pack: uncharacterized phage protein (possible DNA packaging) 4 92 3.5E-27 T 28-03-2018 IPR006450 Phage protein of unkonwn function CO689_RS11920 985eb723890096cdc9d28c11b29cb219 326 SUPERFAMILY SSF52540 6 257 1.61E-68 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CO689_RS11920 985eb723890096cdc9d28c11b29cb219 326 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 237 302 8.0E-21 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CO689_RS11920 985eb723890096cdc9d28c11b29cb219 326 ProSitePatterns PS00211 ABC transporters family signature. 158 172 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CO689_RS11920 985eb723890096cdc9d28c11b29cb219 326 Pfam PF00005 ABC transporter 27 185 1.2E-28 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CO689_RS11920 985eb723890096cdc9d28c11b29cb219 326 SMART SM00382 35 243 6.6E-14 T 28-03-2018 IPR003593 AAA+ ATPase domain CO689_RS11920 985eb723890096cdc9d28c11b29cb219 326 Gene3D G3DSA:3.40.50.300 3 326 4.9E-81 T 28-03-2018 CO689_RS11920 985eb723890096cdc9d28c11b29cb219 326 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 236 322 3.8E-29 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CO689_RS02810 01f76ca6373a276e5c922e729937e73f 397 SUPERFAMILY SSF53448 5 395 6.68E-117 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CO689_RS02810 01f76ca6373a276e5c922e729937e73f 397 Pfam PF01704 UTP--glucose-1-phosphate uridylyltransferase 49 377 8.8E-39 T 28-03-2018 IPR002618 UDPGP family GO:0008152|GO:0070569 CO689_RS02810 01f76ca6373a276e5c922e729937e73f 397 Gene3D G3DSA:3.90.550.10 3 396 1.6E-103 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CO689_RS12350 3b873b70372312ff503abf33ff66f5c8 409 PIRSF PIRSF001413 4 407 1.9E-166 T 28-03-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 CO689_RS12350 3b873b70372312ff503abf33ff66f5c8 409 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 63 388 1.6E-42 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CO689_RS12350 3b873b70372312ff503abf33ff66f5c8 409 Hamap MF_00133 Tryptophan synthase beta chain [trpB]. 12 401 51.27 T 28-03-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 CO689_RS12350 3b873b70372312ff503abf33ff66f5c8 409 SUPERFAMILY SSF53686 16 399 3.14E-144 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CO689_RS12350 3b873b70372312ff503abf33ff66f5c8 409 Gene3D G3DSA:3.40.50.1100 19 76 1.6E-9 T 28-03-2018 CO689_RS12350 3b873b70372312ff503abf33ff66f5c8 409 Gene3D G3DSA:3.40.50.1100 77 207 2.9E-37 T 28-03-2018 CO689_RS12350 3b873b70372312ff503abf33ff66f5c8 409 Gene3D G3DSA:3.40.50.1100 208 409 1.4E-38 T 28-03-2018 CO689_RS12350 3b873b70372312ff503abf33ff66f5c8 409 TIGRFAM TIGR00263 trpB: tryptophan synthase, beta subunit 17 400 7.2E-197 T 28-03-2018 IPR006654 Tryptophan synthase, beta chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 CO689_RS12350 3b873b70372312ff503abf33ff66f5c8 409 ProSitePatterns PS00168 Tryptophan synthase beta chain pyridoxal-phosphate attachment site. 91 105 - T 28-03-2018 IPR006653 Tryptophan synthase, beta chain, conserved site GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 CO689_RS13525 91f6287b8238454170e5c767fe15f81b 758 SUPERFAMILY SSF82866 219 413 4.05E-38 T 28-03-2018 CO689_RS13525 91f6287b8238454170e5c767fe15f81b 758 Hamap MF_01464_B Protein-export membrane protein SecF [secF]. 451 734 26.019 T 28-03-2018 IPR005665 Protein-export membrane protein SecF, bacterial GO:0006886|GO:0015450 CO689_RS13525 91f6287b8238454170e5c767fe15f81b 758 TIGRFAM TIGR01129 secD: protein-export membrane protein SecD 34 409 7.5E-99 T 28-03-2018 IPR005791 Protein translocase subunit SecD GO:0006886|GO:0015450 CO689_RS13525 91f6287b8238454170e5c767fe15f81b 758 Gene3D G3DSA:1.20.1640.10 525 743 4.6E-32 T 28-03-2018 CO689_RS13525 91f6287b8238454170e5c767fe15f81b 758 SUPERFAMILY SSF82866 540 734 4.71E-37 T 28-03-2018 CO689_RS13525 91f6287b8238454170e5c767fe15f81b 758 TIGRFAM TIGR00916 2A0604s01: protein-export membrane protein, SecD/SecF family 186 402 1.9E-52 T 28-03-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial CO689_RS13525 91f6287b8238454170e5c767fe15f81b 758 TIGRFAM TIGR00916 2A0604s01: protein-export membrane protein, SecD/SecF family 523 720 3.1E-51 T 28-03-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial CO689_RS13525 91f6287b8238454170e5c767fe15f81b 758 Pfam PF07549 SecD/SecF GG Motif 473 498 7.7E-8 T 28-03-2018 IPR022646 Protein-export membrane protein SecD/SecF/SecDF, conserved site CO689_RS13525 91f6287b8238454170e5c767fe15f81b 758 Pfam PF02355 Protein export membrane protein 554 732 2.7E-64 T 28-03-2018 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial CO689_RS13525 91f6287b8238454170e5c767fe15f81b 758 Pfam PF02355 Protein export membrane protein 242 412 9.2E-14 T 28-03-2018 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial CO689_RS13525 91f6287b8238454170e5c767fe15f81b 758 TIGRFAM TIGR00966 3a0501s07: protein-export membrane protein SecF 480 723 3.1E-70 T 28-03-2018 IPR005665 Protein-export membrane protein SecF, bacterial GO:0006886|GO:0015450 CO689_RS13525 91f6287b8238454170e5c767fe15f81b 758 Hamap MF_01463_B Protein translocase subunit SecD [secD]. 2 423 31.03 T 28-03-2018 IPR005791 Protein translocase subunit SecD GO:0006886|GO:0015450 CO689_RS13525 91f6287b8238454170e5c767fe15f81b 758 Gene3D G3DSA:1.20.1640.10 201 415 3.9E-30 T 28-03-2018 CO689_RS13525 91f6287b8238454170e5c767fe15f81b 758 PRINTS PR01755 Bacterial translocase SecF protein signature 635 653 7.4E-27 T 28-03-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial CO689_RS13525 91f6287b8238454170e5c767fe15f81b 758 PRINTS PR01755 Bacterial translocase SecF protein signature 478 493 7.4E-27 T 28-03-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial CO689_RS13525 91f6287b8238454170e5c767fe15f81b 758 PRINTS PR01755 Bacterial translocase SecF protein signature 671 686 7.4E-27 T 28-03-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial CO689_RS13525 91f6287b8238454170e5c767fe15f81b 758 PRINTS PR01755 Bacterial translocase SecF protein signature 587 601 7.4E-27 T 28-03-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial CO689_RS01370 a50b0bfc1608a17dea9d0b3a5abffbe3 978 Gene3D G3DSA:3.40.50.300 1 324 2.5E-10 T 28-03-2018 CO689_RS01370 a50b0bfc1608a17dea9d0b3a5abffbe3 978 Gene3D G3DSA:3.40.50.300 711 961 7.2E-10 T 28-03-2018 CO689_RS01370 a50b0bfc1608a17dea9d0b3a5abffbe3 978 SUPERFAMILY SSF52540 880 969 1.08E-8 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CO689_RS01370 a50b0bfc1608a17dea9d0b3a5abffbe3 978 SUPERFAMILY SSF52540 17 148 1.08E-8 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CO689_RS01370 a50b0bfc1608a17dea9d0b3a5abffbe3 978 SUPERFAMILY SSF52540 716 956 3.45E-9 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CO689_RS01370 a50b0bfc1608a17dea9d0b3a5abffbe3 978 Gene3D G3DSA:1.20.5.340 512 623 1.5E-5 T 28-03-2018 CO689_RS01370 a50b0bfc1608a17dea9d0b3a5abffbe3 978 Gene3D G3DSA:1.20.5.50 624 710 5.1E-5 T 28-03-2018 CO689_RS01370 a50b0bfc1608a17dea9d0b3a5abffbe3 978 Pfam PF13514 AAA domain 1 203 7.4E-27 T 28-03-2018 CO689_RS12705 e814e8d7f24227106cc5a6b9ca84c56f 222 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 35 169 3.1E-24 T 28-03-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 CO689_RS12705 e814e8d7f24227106cc5a6b9ca84c56f 222 Gene3D G3DSA:1.10.340.30 21 118 3.0E-26 T 28-03-2018 CO689_RS12705 e814e8d7f24227106cc5a6b9ca84c56f 222 Pfam PF00633 Helix-hairpin-helix motif 100 128 6.8E-8 T 28-03-2018 IPR000445 Helix-hairpin-helix motif GO:0003677 Reactome: R-HSA-110357 CO689_RS12705 e814e8d7f24227106cc5a6b9ca84c56f 222 TIGRFAM TIGR01083 nth: endonuclease III 5 196 4.5E-84 T 28-03-2018 IPR005759 Endonuclease III GO:0003906|GO:0006284 CO689_RS12705 e814e8d7f24227106cc5a6b9ca84c56f 222 SUPERFAMILY SSF48150 1 211 2.36E-71 T 28-03-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 CO689_RS12705 e814e8d7f24227106cc5a6b9ca84c56f 222 Hamap MF_00942 Endonuclease III [nth]. 1 211 38.991 T 28-03-2018 IPR005759 Endonuclease III GO:0003906|GO:0006284 CO689_RS12705 e814e8d7f24227106cc5a6b9ca84c56f 222 PIRSF PIRSF001435 1 214 5.8E-58 T 28-03-2018 CO689_RS12705 e814e8d7f24227106cc5a6b9ca84c56f 222 Gene3D G3DSA:1.10.1670.10 119 222 1.5E-33 T 28-03-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 CO689_RS12705 e814e8d7f24227106cc5a6b9ca84c56f 222 ProSitePatterns PS01155 Endonuclease III family signature. 103 132 - T 28-03-2018 IPR004036 Endonuclease III-like, conserved site-2 Reactome: R-HSA-110357 CO689_RS12705 e814e8d7f24227106cc5a6b9ca84c56f 222 SMART SM00478 39 187 1.9E-62 T 28-03-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 CO689_RS12705 e814e8d7f24227106cc5a6b9ca84c56f 222 Pfam PF10576 Iron-sulfur binding domain of endonuclease III 189 205 1.6E-4 T 28-03-2018 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: R-HSA-110357 CO689_RS11595 fcf4bea4d5e5d33571e364fa5362337c 870 Pfam PF09586 Bacterial membrane protein YfhO 21 848 4.6E-135 T 28-03-2018 IPR018580 Uncharacterised protein family YfhO CO689_RS01825 a9e7cfa18a4ab39e16ee488fd9db28f3 229 Hamap MF_00112 Geranylgeranylglyceryl phosphate synthase [pcrB]. 3 226 25.334 T 28-03-2018 IPR008205 Geranylgeranylglyceryl phosphate synthase/Heptaprenylglyceryl phosphate synthase GO:0016765 CO689_RS01825 a9e7cfa18a4ab39e16ee488fd9db28f3 229 SUPERFAMILY SSF51395 4 224 5.13E-44 T 28-03-2018 CO689_RS01825 a9e7cfa18a4ab39e16ee488fd9db28f3 229 TIGRFAM TIGR01768 GGGP-family: geranylgeranylglyceryl phosphate synthase family protein 9 223 1.2E-63 T 28-03-2018 IPR008205 Geranylgeranylglyceryl phosphate synthase/Heptaprenylglyceryl phosphate synthase GO:0016765 CO689_RS01825 a9e7cfa18a4ab39e16ee488fd9db28f3 229 Gene3D G3DSA:3.20.20.390 1 224 5.8E-22 T 28-03-2018 CO689_RS01825 a9e7cfa18a4ab39e16ee488fd9db28f3 229 Pfam PF01884 PcrB family 2 224 2.8E-69 T 28-03-2018 IPR008205 Geranylgeranylglyceryl phosphate synthase/Heptaprenylglyceryl phosphate synthase GO:0016765 CO689_RS05440 46681341ea3c3ddbb78be3be6375049b 414 Pfam PF13200 Putative glycosyl hydrolase domain 56 379 1.1E-119 T 28-03-2018 IPR025275 Putative glycosyl hydrolase domain DUF4015 CO689_RS05440 46681341ea3c3ddbb78be3be6375049b 414 Gene3D G3DSA:3.20.20.80 56 407 4.4E-17 T 28-03-2018 CO689_RS05440 46681341ea3c3ddbb78be3be6375049b 414 SUPERFAMILY SSF51445 112 386 1.02E-10 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CO689_RS10025 3c5fbcc2dc6655e60e61697962ab3cb8 85 Gene3D G3DSA:1.10.340.20 4 80 1.4E-14 T 28-03-2018 CO689_RS10025 3c5fbcc2dc6655e60e61697962ab3cb8 85 ProDom PD062625 YUGE 10 85 9.0E-5 T 28-03-2018 IPR015053 Protein of unknown function DUF1871 CO689_RS10025 3c5fbcc2dc6655e60e61697962ab3cb8 85 SUPERFAMILY SSF116922 6 78 7.85E-12 T 28-03-2018 IPR023162 Apc36109-like domain CO689_RS10025 3c5fbcc2dc6655e60e61697962ab3cb8 85 Pfam PF08958 Domain of unknown function (DUF1871) 10 79 1.3E-14 T 28-03-2018 IPR015053 Protein of unknown function DUF1871 CO689_RS13350 b5446eb657cff3bd167d3d8669c42536 238 SUPERFAMILY SSF53335 4 238 2.11E-45 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CO689_RS13350 b5446eb657cff3bd167d3d8669c42536 238 Pfam PF13649 Methyltransferase domain 37 127 1.8E-16 T 28-03-2018 CO689_RS13350 b5446eb657cff3bd167d3d8669c42536 238 Gene3D G3DSA:3.40.50.150 1 132 7.2E-23 T 28-03-2018 CO689_RS13350 b5446eb657cff3bd167d3d8669c42536 238 Gene3D G3DSA:2.20.25.110 135 197 3.3E-15 T 28-03-2018 CO689_RS01635 e77262bce43e2ebe739c9da50c57fa24 180 Gene3D G3DSA:2.40.380.10 18 173 4.6E-35 T 28-03-2018 IPR007295 Domain of unknown function DUF402 CO689_RS01635 e77262bce43e2ebe739c9da50c57fa24 180 PIRSF PIRSF028345 4 180 5.6E-80 T 28-03-2018 IPR016882 Uncharacterised protein family UPF0374 CO689_RS01635 e77262bce43e2ebe739c9da50c57fa24 180 SUPERFAMILY SSF159234 7 172 1.2E-32 T 28-03-2018 IPR007295 Domain of unknown function DUF402 CO689_RS01635 e77262bce43e2ebe739c9da50c57fa24 180 Pfam PF04167 Protein of unknown function (DUF402) 63 127 8.8E-18 T 28-03-2018 IPR007295 Domain of unknown function DUF402 CO689_RS01635 e77262bce43e2ebe739c9da50c57fa24 180 Hamap MF_01568 UPF0374 protein . 4 178 50.709 T 28-03-2018 IPR016882 Uncharacterised protein family UPF0374 CO689_RS05705 51021c9758355ce37072b9aaece4a9eb 1512 SUPERFAMILY SSF117074 906 1007 3.4E-22 T 28-03-2018 CO689_RS05705 51021c9758355ce37072b9aaece4a9eb 1512 SUPERFAMILY SSF117074 1257 1357 1.31E-21 T 28-03-2018 CO689_RS05705 51021c9758355ce37072b9aaece4a9eb 1512 SUPERFAMILY SSF117074 674 764 1.83E-19 T 28-03-2018 CO689_RS05705 51021c9758355ce37072b9aaece4a9eb 1512 SUPERFAMILY SSF49401 258 400 3.48E-27 T 28-03-2018 IPR008966 Adhesion domain CO689_RS05705 51021c9758355ce37072b9aaece4a9eb 1512 SUPERFAMILY SSF117074 1138 1242 3.66E-21 T 28-03-2018 CO689_RS05705 51021c9758355ce37072b9aaece4a9eb 1512 SUPERFAMILY SSF117074 575 665 3.53E-20 T 28-03-2018 CO689_RS05705 51021c9758355ce37072b9aaece4a9eb 1512 TIGRFAM TIGR01168 YSIRK_signal: gram-positive signal peptide, YSIRK family 11 47 5.4E-12 T 28-03-2018 IPR005877 YSIRK Gram-positive signal peptide GO:0016020 CO689_RS05705 51021c9758355ce37072b9aaece4a9eb 1512 SUPERFAMILY SSF49401 414 601 2.86E-32 T 28-03-2018 IPR008966 Adhesion domain CO689_RS05705 51021c9758355ce37072b9aaece4a9eb 1512 Gene3D G3DSA:2.60.40.1290 409 561 3.6E-31 T 28-03-2018 CO689_RS05705 51021c9758355ce37072b9aaece4a9eb 1512 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 1475 1506 3.2E-5 T 28-03-2018 CO689_RS05705 51021c9758355ce37072b9aaece4a9eb 1512 SUPERFAMILY SSF117074 786 883 1.57E-20 T 28-03-2018 CO689_RS05705 51021c9758355ce37072b9aaece4a9eb 1512 Pfam PF10425 C-terminus of bacterial fibrinogen-binding adhesin 416 557 7.4E-23 T 28-03-2018 IPR011266 Fibrinogen-binding domain 2 GO:0005618|GO:0007155 CO689_RS05705 51021c9758355ce37072b9aaece4a9eb 1512 Pfam PF04650 YSIRK type signal peptide 13 36 9.9E-9 T 28-03-2018 IPR005877 YSIRK Gram-positive signal peptide GO:0016020 CO689_RS05705 51021c9758355ce37072b9aaece4a9eb 1512 Gene3D G3DSA:2.60.40.10 807 923 1.3E-22 T 28-03-2018 IPR013783 Immunoglobulin-like fold CO689_RS05705 51021c9758355ce37072b9aaece4a9eb 1512 Gene3D G3DSA:2.60.40.10 1160 1274 6.8E-25 T 28-03-2018 IPR013783 Immunoglobulin-like fold CO689_RS05705 51021c9758355ce37072b9aaece4a9eb 1512 Gene3D G3DSA:2.60.40.10 925 1040 3.6E-24 T 28-03-2018 IPR013783 Immunoglobulin-like fold CO689_RS05705 51021c9758355ce37072b9aaece4a9eb 1512 Gene3D G3DSA:2.60.40.10 1276 1393 2.0E-23 T 28-03-2018 IPR013783 Immunoglobulin-like fold CO689_RS05705 51021c9758355ce37072b9aaece4a9eb 1512 Gene3D G3DSA:2.60.40.10 692 805 7.8E-23 T 28-03-2018 IPR013783 Immunoglobulin-like fold CO689_RS05705 51021c9758355ce37072b9aaece4a9eb 1512 Gene3D G3DSA:2.60.40.10 1042 1157 1.5E-23 T 28-03-2018 IPR013783 Immunoglobulin-like fold CO689_RS05705 51021c9758355ce37072b9aaece4a9eb 1512 Gene3D G3DSA:2.60.40.10 576 691 2.8E-24 T 28-03-2018 IPR013783 Immunoglobulin-like fold CO689_RS05705 51021c9758355ce37072b9aaece4a9eb 1512 Pfam PF17210 SdrD B-like domain 581 684 4.5E-30 T 28-03-2018 IPR033764 SD-repeat containing protein, B domain CO689_RS05705 51021c9758355ce37072b9aaece4a9eb 1512 Pfam PF17210 SdrD B-like domain 1281 1382 3.2E-28 T 28-03-2018 IPR033764 SD-repeat containing protein, B domain CO689_RS05705 51021c9758355ce37072b9aaece4a9eb 1512 Pfam PF17210 SdrD B-like domain 930 1031 1.2E-27 T 28-03-2018 IPR033764 SD-repeat containing protein, B domain CO689_RS05705 51021c9758355ce37072b9aaece4a9eb 1512 Pfam PF17210 SdrD B-like domain 812 915 6.0E-30 T 28-03-2018 IPR033764 SD-repeat containing protein, B domain CO689_RS05705 51021c9758355ce37072b9aaece4a9eb 1512 Pfam PF17210 SdrD B-like domain 1164 1265 2.9E-28 T 28-03-2018 IPR033764 SD-repeat containing protein, B domain CO689_RS05705 51021c9758355ce37072b9aaece4a9eb 1512 Pfam PF17210 SdrD B-like domain 1047 1148 2.5E-27 T 28-03-2018 IPR033764 SD-repeat containing protein, B domain CO689_RS05705 51021c9758355ce37072b9aaece4a9eb 1512 Pfam PF17210 SdrD B-like domain 694 796 1.0E-29 T 28-03-2018 IPR033764 SD-repeat containing protein, B domain CO689_RS05705 51021c9758355ce37072b9aaece4a9eb 1512 SUPERFAMILY SSF117074 1021 1124 1.18E-21 T 28-03-2018 CO689_RS05705 51021c9758355ce37072b9aaece4a9eb 1512 Gene3D G3DSA:2.60.40.1280 258 408 4.3E-31 T 28-03-2018 IPR011252 Fibrogen-binding domain 1 GO:0005618|GO:0007155 CO689_RS05705 51021c9758355ce37072b9aaece4a9eb 1512 Pfam PF00746 LPXTG cell wall anchor motif 1468 1508 7.2E-10 T 28-03-2018 IPR019948 Gram-positive LPXTG cell wall anchor CO689_RS08105 6edba37df82995e0a8c413a96e219703 333 Pfam PF02275 Linear amide C-N hydrolases, choloylglycine hydrolase family 2 314 5.7E-76 T 28-03-2018 IPR029132 Choloylglycine hydrolase/NAAA C-terminal CO689_RS08105 6edba37df82995e0a8c413a96e219703 333 SUPERFAMILY SSF56235 2 323 1.54E-86 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CO689_RS08105 6edba37df82995e0a8c413a96e219703 333 Gene3D G3DSA:3.60.60.10 2 332 8.2E-70 T 28-03-2018 CO689_RS04435 6a46ef61547c03198248744bd3463cf8 293 Gene3D G3DSA:3.40.190.10 177 265 7.3E-17 T 28-03-2018 CO689_RS04435 6a46ef61547c03198248744bd3463cf8 293 SUPERFAMILY SSF53850 90 291 3.04E-32 T 28-03-2018 CO689_RS04435 6a46ef61547c03198248744bd3463cf8 293 SUPERFAMILY SSF46785 1 86 2.29E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS04435 6a46ef61547c03198248744bd3463cf8 293 Gene3D G3DSA:3.40.190.10 87 176 5.2E-18 T 28-03-2018 CO689_RS04435 6a46ef61547c03198248744bd3463cf8 293 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 9.8E-20 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CO689_RS04435 6a46ef61547c03198248744bd3463cf8 293 Gene3D G3DSA:1.10.10.10 1 83 8.9E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS04435 6a46ef61547c03198248744bd3463cf8 293 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 2.0E-8 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CO689_RS04435 6a46ef61547c03198248744bd3463cf8 293 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 2.0E-8 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CO689_RS04435 6a46ef61547c03198248744bd3463cf8 293 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 2.0E-8 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CO689_RS04435 6a46ef61547c03198248744bd3463cf8 293 Pfam PF03466 LysR substrate binding domain 88 290 2.6E-36 T 28-03-2018 IPR005119 LysR, substrate-binding CO689_RS10345 690d90aa4b1406aa6e7514c1cdc413e7 563 Gene3D G3DSA:2.40.10.10 355 464 3.7E-27 T 28-03-2018 CO689_RS10345 690d90aa4b1406aa6e7514c1cdc413e7 563 SUPERFAMILY SSF50156 447 562 3.68E-14 T 28-03-2018 IPR001478 PDZ domain GO:0005515 CO689_RS10345 690d90aa4b1406aa6e7514c1cdc413e7 563 SUPERFAMILY SSF50494 242 461 1.76E-41 T 28-03-2018 IPR009003 Peptidase S1, PA clan CO689_RS10345 690d90aa4b1406aa6e7514c1cdc413e7 563 PRINTS PR00834 HtrA/DegQ protease family signature 510 522 3.7E-24 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CO689_RS10345 690d90aa4b1406aa6e7514c1cdc413e7 563 PRINTS PR00834 HtrA/DegQ protease family signature 290 302 3.7E-24 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CO689_RS10345 690d90aa4b1406aa6e7514c1cdc413e7 563 PRINTS PR00834 HtrA/DegQ protease family signature 311 331 3.7E-24 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CO689_RS10345 690d90aa4b1406aa6e7514c1cdc413e7 563 PRINTS PR00834 HtrA/DegQ protease family signature 354 378 3.7E-24 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CO689_RS10345 690d90aa4b1406aa6e7514c1cdc413e7 563 PRINTS PR00834 HtrA/DegQ protease family signature 398 415 3.7E-24 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CO689_RS10345 690d90aa4b1406aa6e7514c1cdc413e7 563 PRINTS PR00834 HtrA/DegQ protease family signature 420 437 3.7E-24 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CO689_RS10345 690d90aa4b1406aa6e7514c1cdc413e7 563 SMART SM00228 465 553 3.2E-5 T 28-03-2018 IPR001478 PDZ domain GO:0005515 CO689_RS10345 690d90aa4b1406aa6e7514c1cdc413e7 563 Pfam PF13180 PDZ domain 482 562 3.6E-11 T 28-03-2018 IPR001478 PDZ domain GO:0005515 CO689_RS10345 690d90aa4b1406aa6e7514c1cdc413e7 563 Gene3D G3DSA:2.40.10.10 237 354 1.3E-18 T 28-03-2018 CO689_RS10345 690d90aa4b1406aa6e7514c1cdc413e7 563 Gene3D G3DSA:2.30.42.10 465 563 3.0E-18 T 28-03-2018 CO689_RS10345 690d90aa4b1406aa6e7514c1cdc413e7 563 Pfam PF13365 Trypsin-like peptidase domain 278 427 2.9E-27 T 28-03-2018 CO689_RS01615 19edadb99366b5568721d2644724cb53 151 PIRSF PIRSF000239 1 145 1.8E-25 T 28-03-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 CO689_RS01615 19edadb99366b5568721d2644724cb53 151 SUPERFAMILY SSF52833 1 150 3.99E-46 T 28-03-2018 IPR012336 Thioredoxin-like fold CO689_RS01615 19edadb99366b5568721d2644724cb53 151 Gene3D G3DSA:3.40.30.10 1 151 3.1E-36 T 28-03-2018 CO689_RS01615 19edadb99366b5568721d2644724cb53 151 Pfam PF00578 AhpC/TSA family 5 132 5.2E-35 T 28-03-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 CO689_RS07920 b69fa367f21266fe2720e9ae7a85d00e 192 SUPERFAMILY SSF52317 2 182 1.16E-46 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CO689_RS07920 b69fa367f21266fe2720e9ae7a85d00e 192 Gene3D G3DSA:3.40.50.880 1 192 5.8E-38 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CO689_RS07920 b69fa367f21266fe2720e9ae7a85d00e 192 PIRSF PIRSF005639 1 187 3.3E-67 T 28-03-2018 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 CO689_RS07920 b69fa367f21266fe2720e9ae7a85d00e 192 TIGRFAM TIGR03800 PLP_synth_Pdx2: pyridoxal 5'-phosphate synthase, glutaminase subunit Pdx2 2 181 1.5E-81 T 28-03-2018 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 CO689_RS07920 b69fa367f21266fe2720e9ae7a85d00e 192 Pfam PF01174 SNO glutamine amidotransferase family 5 184 2.9E-69 T 28-03-2018 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 CO689_RS07920 b69fa367f21266fe2720e9ae7a85d00e 192 Hamap MF_01615 Pyridoxal 5'-phosphate synthase subunit PdxT [pdxT]. 3 182 35.48 T 28-03-2018 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 CO689_RS07920 b69fa367f21266fe2720e9ae7a85d00e 192 ProSitePatterns PS01236 PdxT/SNO family family signature. 40 50 - T 28-03-2018 IPR021196 PdxT/SNO family, conserved site KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 CO689_RS11865 25dbfd31d6026cd58c1c863a56a55688 519 TIGRFAM TIGR00277 HDIG: HDIG domain 331 408 9.1E-24 T 28-03-2018 IPR006675 HDIG domain CO689_RS11865 25dbfd31d6026cd58c1c863a56a55688 519 SMART SM00322 207 274 6.2E-7 T 28-03-2018 IPR004087 K Homology domain GO:0003676 CO689_RS11865 25dbfd31d6026cd58c1c863a56a55688 519 TIGRFAM TIGR03319 RNase_Y: ribonuclease Y 7 519 2.1E-238 T 28-03-2018 IPR017705 Ribonuclease Y GO:0003723|GO:0006402|GO:0016020 CO689_RS11865 25dbfd31d6026cd58c1c863a56a55688 519 Gene3D G3DSA:1.20.5.620 30 89 6.8E-4 T 28-03-2018 IPR028987 F-type ATP synthase subunit B-like, membrane domain CO689_RS11865 25dbfd31d6026cd58c1c863a56a55688 519 SUPERFAMILY SSF54791 207 303 9.22E-17 T 28-03-2018 IPR004088 K Homology domain, type 1 GO:0003723 CO689_RS11865 25dbfd31d6026cd58c1c863a56a55688 519 SMART SM00471 331 437 6.0E-12 T 28-03-2018 IPR003607 HD/PDEase domain CO689_RS11865 25dbfd31d6026cd58c1c863a56a55688 519 SUPERFAMILY SSF109604 319 469 1.55E-29 T 28-03-2018 CO689_RS11865 25dbfd31d6026cd58c1c863a56a55688 519 Gene3D G3DSA:1.10.3210.10 243 474 9.9E-36 T 28-03-2018 CO689_RS11865 25dbfd31d6026cd58c1c863a56a55688 519 Pfam PF00013 KH domain 212 268 1.9E-6 T 28-03-2018 IPR004088 K Homology domain, type 1 GO:0003723 CO689_RS11865 25dbfd31d6026cd58c1c863a56a55688 519 Gene3D G3DSA:3.30.300.20 168 242 2.5E-12 T 28-03-2018 IPR015946 K homology domain-like, alpha/beta CO689_RS11865 25dbfd31d6026cd58c1c863a56a55688 519 Pfam PF01966 HD domain 336 427 3.1E-18 T 28-03-2018 IPR006674 HD domain CO689_RS11865 25dbfd31d6026cd58c1c863a56a55688 519 Hamap MF_00335 Ribonuclease Y [rny]. 4 519 25.3 T 28-03-2018 IPR017705 Ribonuclease Y GO:0003723|GO:0006402|GO:0016020 CO689_RS11865 25dbfd31d6026cd58c1c863a56a55688 519 Pfam PF12072 Domain of unknown function (DUF3552) 6 204 4.4E-59 T 28-03-2018 IPR022711 Ribonuclease Y, N-terminal CO689_RS02530 15874d466d4edb9e9dd30888c9d9ea3f 86 SUPERFAMILY SSF143800 1 80 7.85E-24 T 28-03-2018 IPR034704 L28p-like Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CO689_RS02530 15874d466d4edb9e9dd30888c9d9ea3f 86 TIGRFAM TIGR00105 L31: ribosomal protein bL31 1 80 1.5E-19 T 28-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CO689_RS02530 15874d466d4edb9e9dd30888c9d9ea3f 86 Pfam PF01197 Ribosomal protein L31 1 79 6.0E-27 T 28-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CO689_RS02530 15874d466d4edb9e9dd30888c9d9ea3f 86 ProSitePatterns PS01143 Ribosomal protein L31 signature. 49 70 - T 28-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CO689_RS02530 15874d466d4edb9e9dd30888c9d9ea3f 86 Hamap MF_00502 50S ribosomal protein L31 type B [rpmE2]. 1 81 27.695 T 28-03-2018 IPR027493 Ribosomal protein L31 type B GO:0003735|GO:0005622|GO:0005840|GO:0006412 CO689_RS02530 15874d466d4edb9e9dd30888c9d9ea3f 86 PRINTS PR01249 Ribosomal protein L31 signature 60 78 2.5E-18 T 28-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CO689_RS02530 15874d466d4edb9e9dd30888c9d9ea3f 86 PRINTS PR01249 Ribosomal protein L31 signature 45 60 2.5E-18 T 28-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CO689_RS02530 15874d466d4edb9e9dd30888c9d9ea3f 86 PRINTS PR01249 Ribosomal protein L31 signature 2 19 2.5E-18 T 28-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CO689_RS06835 1317450595f52e0dfb2f1855cd02b4fc 103 Pfam PF06124 Staphylococcal protein of unknown function (DUF960) 4 102 3.8E-27 T 28-03-2018 IPR009303 Protein of unknown function DUF960 CO689_RS06835 1317450595f52e0dfb2f1855cd02b4fc 103 Gene3D G3DSA:3.10.450.150 1 102 4.9E-32 T 28-03-2018 CO689_RS12655 e908ec41356c8fb7e3dcc09a3dcd2b7d 1146 SUPERFAMILY SSF52540 22 273 5.9E-35 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CO689_RS12655 e908ec41356c8fb7e3dcc09a3dcd2b7d 1146 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 41 208 3.7E-14 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 CO689_RS12655 e908ec41356c8fb7e3dcc09a3dcd2b7d 1146 Pfam PF00350 Dynamin family 44 194 5.1E-22 T 28-03-2018 IPR022812 Dynamin superfamily CO689_RS12655 e908ec41356c8fb7e3dcc09a3dcd2b7d 1146 Pfam PF00350 Dynamin family 593 804 4.4E-32 T 28-03-2018 IPR022812 Dynamin superfamily CO689_RS12655 e908ec41356c8fb7e3dcc09a3dcd2b7d 1146 Gene3D G3DSA:3.40.50.300 10 561 9.9E-27 T 28-03-2018 CO689_RS12655 e908ec41356c8fb7e3dcc09a3dcd2b7d 1146 SUPERFAMILY SSF52540 724 866 2.0E-28 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CO689_RS12655 e908ec41356c8fb7e3dcc09a3dcd2b7d 1146 SUPERFAMILY SSF52540 576 691 2.0E-28 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CO689_RS12655 e908ec41356c8fb7e3dcc09a3dcd2b7d 1146 Gene3D G3DSA:3.40.50.300 592 949 4.7E-29 T 28-03-2018 CO689_RS11530 6e0ced946ea808dc9125efe0cc391195 245 Gene3D G3DSA:3.40.50.720 42 245 5.6E-73 T 28-03-2018 CO689_RS11530 6e0ced946ea808dc9125efe0cc391195 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 79 90 2.2E-48 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CO689_RS11530 6e0ced946ea808dc9125efe0cc391195 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 206 226 2.2E-48 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CO689_RS11530 6e0ced946ea808dc9125efe0cc391195 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 173 190 2.2E-48 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CO689_RS11530 6e0ced946ea808dc9125efe0cc391195 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 126 142 2.2E-48 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CO689_RS11530 6e0ced946ea808dc9125efe0cc391195 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 4 21 2.2E-48 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CO689_RS11530 6e0ced946ea808dc9125efe0cc391195 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 152 171 2.2E-48 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CO689_RS11530 6e0ced946ea808dc9125efe0cc391195 245 TIGRFAM TIGR01830 3oxo_ACP_reduc: 3-oxoacyl-[acyl-carrier-protein] reductase 5 242 4.0E-110 T 28-03-2018 IPR011284 3-oxoacyl-(acyl-carrier-protein) reductase GO:0004316|GO:0006633|GO:0051287|GO:0055114 KEGG: 00040+1.1.1.10|KEGG: 00061+1.1.1.100|KEGG: 00780+1.1.1.100|MetaCyc: PWY-5367|MetaCyc: PWY-5515|MetaCyc: PWY-5525|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 CO689_RS11530 6e0ced946ea808dc9125efe0cc391195 245 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 132 140 7.0E-15 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CO689_RS11530 6e0ced946ea808dc9125efe0cc391195 245 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 79 90 7.0E-15 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CO689_RS11530 6e0ced946ea808dc9125efe0cc391195 245 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 152 171 7.0E-15 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CO689_RS11530 6e0ced946ea808dc9125efe0cc391195 245 SUPERFAMILY SSF51735 3 244 2.11E-94 T 28-03-2018 IPR016040 NAD(P)-binding domain CO689_RS11530 6e0ced946ea808dc9125efe0cc391195 245 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 139 167 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CO689_RS11530 6e0ced946ea808dc9125efe0cc391195 245 Gene3D G3DSA:3.40.50.10090 2 41 2.3E-8 T 28-03-2018 CO689_RS11530 6e0ced946ea808dc9125efe0cc391195 245 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 9 242 1.3E-73 T 28-03-2018 CO689_RS11530 6e0ced946ea808dc9125efe0cc391195 245 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 3 183 5.6E-5 T 28-03-2018 CO689_RS12260 34bc20ddc7833b9b5511f7c11e670bc0 674 TIGRFAM TIGR00826 EIIB_glc: PTS system, glucose-like IIB component 404 486 2.0E-20 T 28-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 CO689_RS12260 34bc20ddc7833b9b5511f7c11e670bc0 674 ProSitePatterns PS00371 PTS EIIA domains phosphorylation site signature 1. 592 604 - T 28-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 CO689_RS12260 34bc20ddc7833b9b5511f7c11e670bc0 674 SUPERFAMILY SSF51261 523 672 7.67E-56 T 28-03-2018 IPR011055 Duplicated hybrid motif CO689_RS12260 34bc20ddc7833b9b5511f7c11e670bc0 674 ProSitePatterns PS01035 PTS EIIB domains cysteine phosphorylation site signature. 440 457 - T 28-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 CO689_RS12260 34bc20ddc7833b9b5511f7c11e670bc0 674 Pfam PF00367 phosphotransferase system, EIIB 430 462 1.4E-13 T 28-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 CO689_RS12260 34bc20ddc7833b9b5511f7c11e670bc0 674 TIGRFAM TIGR00830 PTBA: PTS system, glucose subfamily, IIA component 530 650 2.7E-46 T 28-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 CO689_RS12260 34bc20ddc7833b9b5511f7c11e670bc0 674 Gene3D G3DSA:3.30.1360.60 425 500 3.7E-25 T 28-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 CO689_RS12260 34bc20ddc7833b9b5511f7c11e670bc0 674 TIGRFAM TIGR02002 PTS-II-BC-glcB: PTS system, glucose-specific IIBC component 3 502 1.6E-238 T 28-03-2018 IPR011299 PTS system glucose-specific IIBC component GO:0005355|GO:0015758|GO:0016021 CO689_RS12260 34bc20ddc7833b9b5511f7c11e670bc0 674 Gene3D G3DSA:2.70.70.10 517 674 2.8E-58 T 28-03-2018 CO689_RS12260 34bc20ddc7833b9b5511f7c11e670bc0 674 Pfam PF02378 Phosphotransferase system, EIIC 13 344 1.2E-96 T 28-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 CO689_RS12260 34bc20ddc7833b9b5511f7c11e670bc0 674 SUPERFAMILY SSF55604 429 500 1.7E-19 T 28-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 CO689_RS12260 34bc20ddc7833b9b5511f7c11e670bc0 674 Pfam PF00358 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 529 652 5.8E-52 T 28-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 CO689_RS04685 a3996f7256ce42a565467d50a4431b49 301 TIGRFAM TIGR00287 cas1: CRISPR-associated endonuclease Cas1 6 280 1.6E-25 T 28-03-2018 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 CO689_RS04685 a3996f7256ce42a565467d50a4431b49 301 TIGRFAM TIGR03639 cas1_NMENI: CRISPR-associated endonuclease Cas1, subtype II/NMENI 3 277 3.9E-84 T 28-03-2018 IPR019855 CRISPR-associated protein Cas1, NMENI subtype GO:0004520|GO:0043571|GO:0046872 CO689_RS04685 a3996f7256ce42a565467d50a4431b49 301 Pfam PF01867 CRISPR associated protein Cas1 7 231 1.2E-25 T 28-03-2018 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 CO689_RS04685 a3996f7256ce42a565467d50a4431b49 301 Hamap MF_01470 CRISPR-associated endonuclease Cas1 [cas1]. 3 278 15.982 T 28-03-2018 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 CO689_RS06860 877aeb4a955d32a9fd5fb0e9b24c4f79 164 Gene3D G3DSA:3.40.630.30 1 164 1.3E-33 T 28-03-2018 CO689_RS06860 877aeb4a955d32a9fd5fb0e9b24c4f79 164 SUPERFAMILY SSF55729 1 160 3.37E-40 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CO689_RS06860 877aeb4a955d32a9fd5fb0e9b24c4f79 164 Pfam PF13302 Acetyltransferase (GNAT) domain 3 135 8.7E-19 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CO689_RS12210 c764c306ddc695eac6577587e1dfe214 123 TIGRFAM TIGR00220 mscL: large conductance mechanosensitive channel protein 2 117 1.6E-37 T 28-03-2018 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 CO689_RS12210 c764c306ddc695eac6577587e1dfe214 123 Pfam PF01741 Large-conductance mechanosensitive channel, MscL 2 115 1.7E-39 T 28-03-2018 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 CO689_RS12210 c764c306ddc695eac6577587e1dfe214 123 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 72 80 4.8E-12 T 28-03-2018 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 CO689_RS12210 c764c306ddc695eac6577587e1dfe214 123 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 81 90 4.8E-12 T 28-03-2018 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 CO689_RS12210 c764c306ddc695eac6577587e1dfe214 123 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 4 18 4.8E-12 T 28-03-2018 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 CO689_RS12210 c764c306ddc695eac6577587e1dfe214 123 ProSitePatterns PS01327 Large-conductance mechanosensitive channels mscL family signature. 11 24 - T 28-03-2018 IPR019823 Large-conductance mechanosensitive channel, conserved site CO689_RS12210 c764c306ddc695eac6577587e1dfe214 123 SUPERFAMILY SSF81330 10 111 3.14E-32 T 28-03-2018 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 CO689_RS12210 c764c306ddc695eac6577587e1dfe214 123 Hamap MF_00115 Large-conductance mechanosensitive channel [mscL]. 1 118 27.822 T 28-03-2018 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 CO689_RS13460 353d1093ebd89d86e17ef2e5bdfdc501 334 Pfam PF00296 Luciferase-like monooxygenase 21 297 1.5E-36 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CO689_RS13460 353d1093ebd89d86e17ef2e5bdfdc501 334 Gene3D G3DSA:3.20.20.30 10 333 2.1E-67 T 28-03-2018 CO689_RS13460 353d1093ebd89d86e17ef2e5bdfdc501 334 TIGRFAM TIGR03558 oxido_grp_1: luciferase family oxidoreductase, group 1 7 327 2.3E-125 T 28-03-2018 IPR019949 Luciferase family oxidoreductase, group 1 CO689_RS13460 353d1093ebd89d86e17ef2e5bdfdc501 334 SUPERFAMILY SSF51679 4 327 2.09E-81 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CO689_RS09875 a6e194acd8f0da2c5f8403542c0df8b6 129 Pfam PF06265 Protein of unknown function (DUF1027) 4 87 1.3E-35 T 28-03-2018 IPR009370 Protein of unknown function DUF1027 CO689_RS09875 a6e194acd8f0da2c5f8403542c0df8b6 129 PIRSF PIRSF012565 1 129 1.7E-50 T 28-03-2018 IPR009370 Protein of unknown function DUF1027 CO689_RS02095 0cfae68a5f7acab8a3e4c146d22f4464 247 Pfam PF02517 CAAX protease self-immunity 127 218 3.7E-14 T 28-03-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 CO689_RS12525 1afe8d026bccfdaae6b01bb7feefc6cd 630 SUPERFAMILY SSF53300 438 624 6.97E-16 T 28-03-2018 IPR002035 von Willebrand factor, type A CO689_RS12525 1afe8d026bccfdaae6b01bb7feefc6cd 630 Pfam PF00092 von Willebrand factor type A domain 440 591 8.1E-6 T 28-03-2018 IPR002035 von Willebrand factor, type A CO689_RS12525 1afe8d026bccfdaae6b01bb7feefc6cd 630 SMART SM00327 435 626 2.6E-12 T 28-03-2018 IPR002035 von Willebrand factor, type A CO689_RS12525 1afe8d026bccfdaae6b01bb7feefc6cd 630 Gene3D G3DSA:3.40.50.410 435 629 5.4E-13 T 28-03-2018 IPR002035 von Willebrand factor, type A CO689_RS04725 441e8d6e3c15b4b06a52526a567a1051 466 Gene3D G3DSA:1.20.1250.20 29 229 2.7E-12 T 28-03-2018 CO689_RS04725 441e8d6e3c15b4b06a52526a567a1051 466 ProSitePatterns PS00872 Sodium:galactoside symporter family signature. 79 106 - T 28-03-2018 IPR018043 Sodium:galactoside symporter, conserved site GO:0005215|GO:0006814|GO:0016020 CO689_RS04725 441e8d6e3c15b4b06a52526a567a1051 466 Gene3D G3DSA:1.20.1250.20 238 459 1.7E-16 T 28-03-2018 CO689_RS04725 441e8d6e3c15b4b06a52526a567a1051 466 SUPERFAMILY SSF103473 27 453 1.06E-36 T 28-03-2018 IPR020846 Major facilitator superfamily domain CO689_RS04725 441e8d6e3c15b4b06a52526a567a1051 466 Pfam PF13347 MFS/sugar transport protein 30 450 4.4E-95 T 28-03-2018 CO689_RS04725 441e8d6e3c15b4b06a52526a567a1051 466 TIGRFAM TIGR00792 gph: sugar (Glycoside-Pentoside-Hexuronide) transporter 28 461 4.2E-132 T 28-03-2018 IPR001927 Sodium:galactoside symporter GO:0005215|GO:0006814|GO:0016020 CO689_RS11760 ef72cc7b1d7027adc0c421d15d5acca5 115 SUPERFAMILY SSF89919 1 111 6.67E-36 T 28-03-2018 IPR023799 Ribosome-binding factor A domain CO689_RS11760 ef72cc7b1d7027adc0c421d15d5acca5 115 Pfam PF02033 Ribosome-binding factor A 5 108 1.8E-33 T 28-03-2018 IPR000238 Ribosome-binding factor A GO:0006364 CO689_RS11760 ef72cc7b1d7027adc0c421d15d5acca5 115 TIGRFAM TIGR00082 rbfA: ribosome-binding factor A 1 113 9.8E-37 T 28-03-2018 IPR000238 Ribosome-binding factor A GO:0006364 CO689_RS11760 ef72cc7b1d7027adc0c421d15d5acca5 115 ProDom PD007327 FACTOR A RIBOSOME-BINDING PROCESSING RRNA 3D-STRUCTURE RIBOSOMAL-BINDING PRECURSOR A RBFA 7 95 3.0E-39 T 28-03-2018 IPR000238 Ribosome-binding factor A GO:0006364 CO689_RS11760 ef72cc7b1d7027adc0c421d15d5acca5 115 Gene3D G3DSA:3.30.300.20 3 115 2.8E-35 T 28-03-2018 IPR015946 K homology domain-like, alpha/beta CO689_RS11760 ef72cc7b1d7027adc0c421d15d5acca5 115 ProSitePatterns PS01319 Ribosome-binding factor A signature. 74 95 - T 28-03-2018 IPR020053 Ribosome-binding factor A, conserved site GO:0006364 CO689_RS11760 ef72cc7b1d7027adc0c421d15d5acca5 115 Hamap MF_00003 Ribosome-binding factor A [rbfA]. 1 115 24.338 T 28-03-2018 IPR000238 Ribosome-binding factor A GO:0006364 CO689_RS12560 0023f6a065be8000eb6523d0d8c86311 454 SMART SM00387 344 454 2.2E-30 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CO689_RS12560 0023f6a065be8000eb6523d0d8c86311 454 SUPERFAMILY SSF47384 216 296 1.31E-16 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CO689_RS12560 0023f6a065be8000eb6523d0d8c86311 454 SMART SM00304 179 232 0.0083 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CO689_RS12560 0023f6a065be8000eb6523d0d8c86311 454 SMART SM00388 233 300 2.8E-14 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CO689_RS12560 0023f6a065be8000eb6523d0d8c86311 454 SUPERFAMILY SSF158472 181 231 2.22E-5 T 28-03-2018 CO689_RS12560 0023f6a065be8000eb6523d0d8c86311 454 PRINTS PR00344 Bacterial sensor protein C-terminal signature 399 409 3.4E-12 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CO689_RS12560 0023f6a065be8000eb6523d0d8c86311 454 PRINTS PR00344 Bacterial sensor protein C-terminal signature 416 434 3.4E-12 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CO689_RS12560 0023f6a065be8000eb6523d0d8c86311 454 PRINTS PR00344 Bacterial sensor protein C-terminal signature 381 395 3.4E-12 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CO689_RS12560 0023f6a065be8000eb6523d0d8c86311 454 Gene3D G3DSA:3.30.565.10 309 454 7.2E-35 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CO689_RS12560 0023f6a065be8000eb6523d0d8c86311 454 Pfam PF00512 His Kinase A (phospho-acceptor) domain 234 297 1.6E-13 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CO689_RS12560 0023f6a065be8000eb6523d0d8c86311 454 SUPERFAMILY SSF55874 290 452 1.57E-38 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CO689_RS12560 0023f6a065be8000eb6523d0d8c86311 454 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 348 452 2.3E-23 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CO689_RS12560 0023f6a065be8000eb6523d0d8c86311 454 Gene3D G3DSA:1.10.287.130 223 296 1.5E-14 T 28-03-2018 CO689_RS11200 808968a9b4c6226373fd86a4557a08a6 143 Pfam PF02381 MraZ protein, putative antitoxin-like 1 70 3.0E-21 T 28-03-2018 IPR020603 MraZ domain CO689_RS11200 808968a9b4c6226373fd86a4557a08a6 143 Pfam PF02381 MraZ protein, putative antitoxin-like 72 141 3.3E-27 T 28-03-2018 IPR020603 MraZ domain CO689_RS11200 808968a9b4c6226373fd86a4557a08a6 143 ProDom PD006745 MRAZ YABB DIVISION CELL 3D-STRUCTURE UNCHARACTERIZED BCR SIMILAR PROTEIN 1 136 9.0E-70 T 28-03-2018 IPR003444 Transcriptional regulator MraZ GO:0003700|GO:0006355 CO689_RS11200 808968a9b4c6226373fd86a4557a08a6 143 Hamap MF_01008 Transcriptional regulator MraZ [mraZ]. 1 143 59.399 T 28-03-2018 IPR003444 Transcriptional regulator MraZ GO:0003700|GO:0006355 CO689_RS11200 808968a9b4c6226373fd86a4557a08a6 143 Gene3D G3DSA:2.10.260.10 73 122 3.5E-9 T 28-03-2018 CO689_RS11200 808968a9b4c6226373fd86a4557a08a6 143 Gene3D G3DSA:2.10.260.10 1 54 3.6E-4 T 28-03-2018 CO689_RS11200 808968a9b4c6226373fd86a4557a08a6 143 TIGRFAM TIGR00242 TIGR00242: division/cell wall cluster transcriptional repressor MraZ 1 142 5.4E-55 T 28-03-2018 IPR003444 Transcriptional regulator MraZ GO:0003700|GO:0006355 CO689_RS11200 808968a9b4c6226373fd86a4557a08a6 143 SUPERFAMILY SSF89447 1 136 1.35E-53 T 28-03-2018 CO689_RS10815 f9a3960158e49287f48d9eb9c013e3c1 78 Pfam PF00462 Glutaredoxin 4 58 8.8E-9 T 28-03-2018 IPR002109 Glutaredoxin GO:0009055|GO:0015035|GO:0045454 CO689_RS10815 f9a3960158e49287f48d9eb9c013e3c1 78 SUPERFAMILY SSF52833 3 72 3.57E-13 T 28-03-2018 IPR012336 Thioredoxin-like fold CO689_RS10815 f9a3960158e49287f48d9eb9c013e3c1 78 Gene3D G3DSA:3.40.30.10 1 76 1.8E-11 T 28-03-2018 CO689_RS08845 c008176bf4f0b1990a45d652ea8ab139 157 Pfam PF07681 DoxX 13 106 2.4E-9 T 28-03-2018 IPR032808 DoxX family CO689_RS09870 4e5b7f5f779060f2128941b8cf47b8f3 309 SUPERFAMILY SSF102114 21 290 8.24E-63 T 28-03-2018 CO689_RS09870 4e5b7f5f779060f2128941b8cf47b8f3 309 Pfam PF04055 Radical SAM superfamily 65 225 9.7E-14 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CO689_RS09870 4e5b7f5f779060f2128941b8cf47b8f3 309 Hamap MF_00206 Lipoyl synthase [lipA]. 1 297 147.592 T 28-03-2018 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 CO689_RS09870 4e5b7f5f779060f2128941b8cf47b8f3 309 PIRSF PIRSF005963 1 308 1.1E-135 T 28-03-2018 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 CO689_RS09870 4e5b7f5f779060f2128941b8cf47b8f3 309 TIGRFAM TIGR00510 lipA: lipoyl synthase 3 294 4.5E-120 T 28-03-2018 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 CO689_RS09870 4e5b7f5f779060f2128941b8cf47b8f3 309 Pfam PF16881 N-terminal domain of lipoyl synthase of Radical_SAM family 4 46 2.8E-10 T 28-03-2018 IPR031691 Lipoyl synthase, N-terminal KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 CO689_RS09870 4e5b7f5f779060f2128941b8cf47b8f3 309 SMART SM00729 58 266 2.6E-17 T 28-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 CO689_RS09870 4e5b7f5f779060f2128941b8cf47b8f3 309 Gene3D G3DSA:3.20.20.70 3 292 9.4E-26 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CO689_RS11245 e6f54c3faf2201e4b082be593e7292d7 262 Gene3D G3DSA:3.60.140.10 3 262 6.3E-67 T 28-03-2018 CO689_RS11245 e6f54c3faf2201e4b082be593e7292d7 262 SUPERFAMILY SSF64438 7 261 2.01E-71 T 28-03-2018 IPR011324 Cytotoxic necrotizing factor-like, catalytic CO689_RS11245 e6f54c3faf2201e4b082be593e7292d7 262 TIGRFAM TIGR00726 TIGR00726: YfiH family protein 39 260 2.5E-46 T 28-03-2018 IPR003730 Multi-copper polyphenol oxidoreductase CO689_RS11245 e6f54c3faf2201e4b082be593e7292d7 262 Pfam PF02578 Multi-copper polyphenol oxidoreductase laccase 27 260 1.9E-57 T 28-03-2018 IPR003730 Multi-copper polyphenol oxidoreductase CO689_RS07575 227832603e200d5f3b5882054f008212 308 Gene3D G3DSA:3.40.50.300 3 163 4.1E-28 T 28-03-2018 CO689_RS07575 227832603e200d5f3b5882054f008212 308 SUPERFAMILY SSF52540 10 172 1.92E-29 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CO689_RS07575 227832603e200d5f3b5882054f008212 308 Pfam PF09115 DNA polymerase III, delta subunit, C terminal 202 304 1.9E-6 T 28-03-2018 IPR015199 DNA polymerase III, delta subunit, C-terminal GO:0003677|GO:0003887|GO:0006260|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CO689_RS07575 227832603e200d5f3b5882054f008212 308 Pfam PF13177 DNA polymerase III, delta subunit 4 151 2.3E-43 T 28-03-2018 CO689_RS07575 227832603e200d5f3b5882054f008212 308 Gene3D G3DSA:1.20.272.10 190 306 6.0E-20 T 28-03-2018 CO689_RS12180 d5fa212b72afc691161a99b324e201c4 80 Pfam PF05979 Bacterial protein of unknown function (DUF896) 7 70 6.3E-31 T 28-03-2018 IPR009242 Protein of unknown function DUF896 CO689_RS12180 d5fa212b72afc691161a99b324e201c4 80 Hamap MF_01103 UPF0291 protein . 1 62 15.861 T 28-03-2018 IPR009242 Protein of unknown function DUF896 CO689_RS12180 d5fa212b72afc691161a99b324e201c4 80 SUPERFAMILY SSF158221 5 44 6.67E-13 T 28-03-2018 CO689_RS12180 d5fa212b72afc691161a99b324e201c4 80 Gene3D G3DSA:1.10.287.540 6 58 8.4E-23 T 28-03-2018 CO689_RS08800 48127165b4a6972452aaab9e97577f0a 270 PIRSF PIRSF002854 1 268 7.3E-85 T 28-03-2018 IPR004872 Lipoprotein NlpA family CO689_RS08800 48127165b4a6972452aaab9e97577f0a 270 Gene3D G3DSA:3.40.190.10 28 138 1.8E-32 T 28-03-2018 CO689_RS08800 48127165b4a6972452aaab9e97577f0a 270 Gene3D G3DSA:3.40.190.10 139 267 6.3E-37 T 28-03-2018 CO689_RS08800 48127165b4a6972452aaab9e97577f0a 270 SUPERFAMILY SSF53850 28 268 2.1E-68 T 28-03-2018 CO689_RS08800 48127165b4a6972452aaab9e97577f0a 270 Pfam PF03180 NLPA lipoprotein 29 266 1.6E-79 T 28-03-2018 IPR004872 Lipoprotein NlpA family CO689_RS07000 cbfa12d9d1069617f128e92d13d8af8a 894 Gene3D G3DSA:2.120.10.90 501 828 4.6E-123 T 28-03-2018 CO689_RS07000 cbfa12d9d1069617f128e92d13d8af8a 894 Gene3D G3DSA:3.30.1360.40 237 334 9.2E-36 T 28-03-2018 IPR024946 Arginine repressor C-terminal-like domain Reactome: R-HSA-4615885 CO689_RS07000 cbfa12d9d1069617f128e92d13d8af8a 894 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 662 708 6.4E-12 T 28-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 CO689_RS07000 cbfa12d9d1069617f128e92d13d8af8a 894 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 713 755 1.9E-12 T 28-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 CO689_RS07000 cbfa12d9d1069617f128e92d13d8af8a 894 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 507 550 1.2E-11 T 28-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 CO689_RS07000 cbfa12d9d1069617f128e92d13d8af8a 894 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 556 605 7.6E-11 T 28-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 CO689_RS07000 cbfa12d9d1069617f128e92d13d8af8a 894 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 764 810 4.7E-10 T 28-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 CO689_RS07000 cbfa12d9d1069617f128e92d13d8af8a 894 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 615 657 7.7E-10 T 28-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 CO689_RS07000 cbfa12d9d1069617f128e92d13d8af8a 894 Gene3D G3DSA:1.10.268.10 346 488 2.0E-51 T 28-03-2018 IPR013757 Type IIA DNA topoisomerase subunit A, alpha-helical domain GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CO689_RS07000 cbfa12d9d1069617f128e92d13d8af8a 894 TIGRFAM TIGR01063 gyrA: DNA gyrase, A subunit 9 811 0.0 T 28-03-2018 CO689_RS07000 cbfa12d9d1069617f128e92d13d8af8a 894 Pfam PF00521 DNA gyrase/topoisomerase IV, subunit A 33 472 9.2E-160 T 28-03-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CO689_RS07000 cbfa12d9d1069617f128e92d13d8af8a 894 Gene3D G3DSA:3.90.199.10 35 216 8.5E-86 T 28-03-2018 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 Reactome: R-HSA-4615885 CO689_RS07000 cbfa12d9d1069617f128e92d13d8af8a 894 Hamap MF_01897 DNA gyrase subunit A [gyrA]. 6 812 24.775 T 28-03-2018 IPR005743 DNA gyrase, subunit A GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 CO689_RS07000 cbfa12d9d1069617f128e92d13d8af8a 894 SUPERFAMILY SSF56719 31 488 7.98E-180 T 28-03-2018 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Reactome: R-HSA-4615885 CO689_RS07000 cbfa12d9d1069617f128e92d13d8af8a 894 SUPERFAMILY SSF101904 501 825 7.06E-107 T 28-03-2018 IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal CO689_RS07000 cbfa12d9d1069617f128e92d13d8af8a 894 SMART SM00434 12 466 1.4E-293 T 28-03-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CO689_RS04340 76922f6f2fabf83f61db2e3567debea6 331 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 114 299 2.2E-49 T 28-03-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 CO689_RS04340 76922f6f2fabf83f61db2e3567debea6 331 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 8 331 2.0E-25 T 28-03-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 CO689_RS04340 76922f6f2fabf83f61db2e3567debea6 331 Gene3D G3DSA:3.40.50.720 117 302 2.3E-47 T 28-03-2018 CO689_RS04340 76922f6f2fabf83f61db2e3567debea6 331 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 149 176 - T 28-03-2018 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 CO689_RS04340 76922f6f2fabf83f61db2e3567debea6 331 Gene3D G3DSA:3.40.50.720 1 116 3.9E-21 T 28-03-2018 CO689_RS04340 76922f6f2fabf83f61db2e3567debea6 331 SUPERFAMILY SSF51735 103 300 5.14E-51 T 28-03-2018 IPR016040 NAD(P)-binding domain CO689_RS04340 76922f6f2fabf83f61db2e3567debea6 331 ProSitePatterns PS00670 D-isomer specific 2-hydroxyacid dehydrogenases signature 2. 196 218 - T 28-03-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site CO689_RS04340 76922f6f2fabf83f61db2e3567debea6 331 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 225 241 - T 28-03-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site CO689_RS04340 76922f6f2fabf83f61db2e3567debea6 331 SUPERFAMILY SSF52283 1 136 5.53E-33 T 28-03-2018 CO689_RS13660 40d2c0c04f2ec3808e954cfc107e5049 422 SUPERFAMILY SSF53244 295 417 1.26E-24 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CO689_RS13660 40d2c0c04f2ec3808e954cfc107e5049 422 TIGRFAM TIGR01499 folC: bifunctional protein FolC 23 415 1.4E-112 T 28-03-2018 IPR001645 Folylpolyglutamate synthetase GO:0004326|GO:0005524|GO:0009396 KEGG: 00790+6.3.2.17|MetaCyc: PWY-2161|Reactome: R-HSA-196757 CO689_RS13660 40d2c0c04f2ec3808e954cfc107e5049 422 Gene3D G3DSA:3.40.1190.10 1 294 7.9E-73 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CO689_RS13660 40d2c0c04f2ec3808e954cfc107e5049 422 PIRSF PIRSF001563 1 421 4.3E-127 T 28-03-2018 IPR001645 Folylpolyglutamate synthetase GO:0004326|GO:0005524|GO:0009396 KEGG: 00790+6.3.2.17|MetaCyc: PWY-2161|Reactome: R-HSA-196757 CO689_RS13660 40d2c0c04f2ec3808e954cfc107e5049 422 SUPERFAMILY SSF53623 1 293 2.06E-81 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CO689_RS13660 40d2c0c04f2ec3808e954cfc107e5049 422 Pfam PF08245 Mur ligase middle domain 44 267 3.6E-11 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CO689_RS13660 40d2c0c04f2ec3808e954cfc107e5049 422 Pfam PF02875 Mur ligase family, glutamate ligase domain 293 362 6.1E-6 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CO689_RS13660 40d2c0c04f2ec3808e954cfc107e5049 422 Gene3D G3DSA:3.90.190.20 295 420 1.0E-18 T 28-03-2018 CO689_RS03885 53877c8aefbc8a488e06b966dcfd753c 300 SUPERFAMILY SSF103481 196 296 1.23E-8 T 28-03-2018 CO689_RS03885 53877c8aefbc8a488e06b966dcfd753c 300 Pfam PF00892 EamA-like transporter family 10 150 5.0E-20 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CO689_RS03885 53877c8aefbc8a488e06b966dcfd753c 300 Pfam PF00892 EamA-like transporter family 162 295 4.3E-21 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CO689_RS03885 53877c8aefbc8a488e06b966dcfd753c 300 SUPERFAMILY SSF103481 47 152 6.8E-7 T 28-03-2018 CO689_RS04315 9384f5bfb2e6663c77d5590f269d01ce 297 Gene3D G3DSA:3.10.180.10 134 297 1.8E-22 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CO689_RS04315 9384f5bfb2e6663c77d5590f269d01ce 297 SUPERFAMILY SSF54593 3 275 4.12E-42 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CO689_RS04315 9384f5bfb2e6663c77d5590f269d01ce 297 Gene3D G3DSA:3.10.180.10 2 106 1.5E-19 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CO689_RS04315 9384f5bfb2e6663c77d5590f269d01ce 297 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 6 255 3.4E-27 T 28-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CO689_RS03860 deead4f37c00536a76f9b63c49d1320f 148 Gene3D G3DSA:1.10.10.10 1 145 7.7E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS03860 deead4f37c00536a76f9b63c49d1320f 148 SMART SM00347 22 124 1.8E-8 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CO689_RS03860 deead4f37c00536a76f9b63c49d1320f 148 SUPERFAMILY SSF46785 5 137 5.88E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS03860 deead4f37c00536a76f9b63c49d1320f 148 Pfam PF01047 MarR family 29 88 8.6E-7 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CO689_RS06450 3be89f9eb8df20769c63dd76b9f3c3c2 240 Pfam PF07722 Peptidase C26 4 218 1.7E-65 T 28-03-2018 IPR011697 Peptidase C26 GO:0016787 Reactome: R-HSA-6798695 CO689_RS06450 3be89f9eb8df20769c63dd76b9f3c3c2 240 SUPERFAMILY SSF52317 25 237 3.64E-42 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CO689_RS06450 3be89f9eb8df20769c63dd76b9f3c3c2 240 Gene3D G3DSA:3.40.50.880 1 240 7.9E-44 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CO689_RS06680 cf9f6a75c78a46d59d4d241ac58e1a28 397 Gene3D G3DSA:3.50.50.60 136 259 4.7E-42 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CO689_RS06680 cf9f6a75c78a46d59d4d241ac58e1a28 397 Gene3D G3DSA:3.50.50.60 2 94 3.2E-13 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CO689_RS06680 cf9f6a75c78a46d59d4d241ac58e1a28 397 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 5 305 2.4E-18 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CO689_RS06680 cf9f6a75c78a46d59d4d241ac58e1a28 397 SUPERFAMILY SSF51905 119 259 5.93E-26 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CO689_RS06680 cf9f6a75c78a46d59d4d241ac58e1a28 397 SUPERFAMILY SSF51905 4 153 6.79E-27 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CO689_RS06680 cf9f6a75c78a46d59d4d241ac58e1a28 397 Gene3D G3DSA:3.50.50.60 95 135 0.007 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CO689_RS02125 8ca085ac4bf2a346cd529534971cc34a 238 Pfam PF04397 LytTr DNA-binding domain 151 237 6.2E-20 T 28-03-2018 IPR007492 LytTR DNA-binding domain GO:0003677 CO689_RS02125 8ca085ac4bf2a346cd529534971cc34a 238 Gene3D G3DSA:3.40.50.2300 1 144 7.3E-13 T 28-03-2018 CO689_RS02125 8ca085ac4bf2a346cd529534971cc34a 238 Pfam PF00072 Response regulator receiver domain 3 120 2.4E-18 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CO689_RS02125 8ca085ac4bf2a346cd529534971cc34a 238 SMART SM00448 1 120 7.5E-10 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CO689_RS02125 8ca085ac4bf2a346cd529534971cc34a 238 SUPERFAMILY SSF52172 2 134 3.7E-11 T 28-03-2018 IPR011006 CheY-like superfamily CO689_RS02125 8ca085ac4bf2a346cd529534971cc34a 238 SMART SM00850 149 238 5.7E-13 T 28-03-2018 IPR007492 LytTR DNA-binding domain GO:0003677 CO689_RS02125 8ca085ac4bf2a346cd529534971cc34a 238 Gene3D G3DSA:2.40.50.40 145 209 9.5E-15 T 28-03-2018 CO689_RS08465 5f53dd5fce6ee9130b38bfaf19a22ad7 116 Pfam PF09966 Uncharacterized protein conserved in bacteria (DUF2200) 5 115 1.9E-53 T 28-03-2018 IPR014580 Uncharacterised conserved protein UCP033199 CO689_RS08465 5f53dd5fce6ee9130b38bfaf19a22ad7 116 Gene3D G3DSA:1.10.8.290 3 116 1.4E-55 T 28-03-2018 IPR023204 SP1917 domain CO689_RS08465 5f53dd5fce6ee9130b38bfaf19a22ad7 116 PIRSF PIRSF033199 1 116 3.6E-56 T 28-03-2018 IPR014580 Uncharacterised conserved protein UCP033199 CO689_RS00585 ce1d5d6e7a462eb2d6cff4a5e8b654d2 195 SMART SM00857 17 150 4.5E-5 T 28-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CO689_RS00585 ce1d5d6e7a462eb2d6cff4a5e8b654d2 195 Gene3D G3DSA:3.40.50.1390 13 151 6.1E-13 T 28-03-2018 CO689_RS00585 ce1d5d6e7a462eb2d6cff4a5e8b654d2 195 Gene3D G3DSA:1.10.10.60 152 195 2.3E-9 T 28-03-2018 CO689_RS00585 ce1d5d6e7a462eb2d6cff4a5e8b654d2 195 SUPERFAMILY SSF53041 15 150 6.02E-19 T 28-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CO689_RS00585 ce1d5d6e7a462eb2d6cff4a5e8b654d2 195 Pfam PF00239 Resolvase, N terminal domain 18 149 1.4E-15 T 28-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CO689_RS12020 de7b36b72a97f140093b838f215c7156 412 Pfam PF06838 Methionine gamma-lyase 5 406 1.7E-194 T 28-03-2018 IPR009651 Putative methionine gamma-lyase CO689_RS12020 de7b36b72a97f140093b838f215c7156 412 Gene3D G3DSA:3.40.640.10 50 263 6.6E-32 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CO689_RS12020 de7b36b72a97f140093b838f215c7156 412 SUPERFAMILY SSF53383 39 390 3.84E-42 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CO689_RS08060 638d34bd04bc07698300435fdaa2b3f4 137 Pfam PF00164 Ribosomal protein S12/S23 39 136 7.1E-36 T 28-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CO689_RS08060 638d34bd04bc07698300435fdaa2b3f4 137 PRINTS PR01034 Ribosomal protein S12 signature 40 55 3.0E-56 T 28-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CO689_RS08060 638d34bd04bc07698300435fdaa2b3f4 137 PRINTS PR01034 Ribosomal protein S12 signature 71 90 3.0E-56 T 28-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CO689_RS08060 638d34bd04bc07698300435fdaa2b3f4 137 PRINTS PR01034 Ribosomal protein S12 signature 107 123 3.0E-56 T 28-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CO689_RS08060 638d34bd04bc07698300435fdaa2b3f4 137 PRINTS PR01034 Ribosomal protein S12 signature 55 70 3.0E-56 T 28-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CO689_RS08060 638d34bd04bc07698300435fdaa2b3f4 137 PRINTS PR01034 Ribosomal protein S12 signature 123 135 3.0E-56 T 28-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CO689_RS08060 638d34bd04bc07698300435fdaa2b3f4 137 PRINTS PR01034 Ribosomal protein S12 signature 90 107 3.0E-56 T 28-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CO689_RS08060 638d34bd04bc07698300435fdaa2b3f4 137 Hamap MF_00403_B 30S ribosomal protein S12 [rpsL]. 1 136 39.991 T 28-03-2018 IPR005679 Ribosomal protein S12, bacterial-type GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CO689_RS08060 638d34bd04bc07698300435fdaa2b3f4 137 SUPERFAMILY SSF50249 2 136 4.28E-48 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CO689_RS08060 638d34bd04bc07698300435fdaa2b3f4 137 TIGRFAM TIGR00981 rpsL_bact: ribosomal protein uS12 1 137 2.3E-67 T 28-03-2018 IPR005679 Ribosomal protein S12, bacterial-type GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CO689_RS08060 638d34bd04bc07698300435fdaa2b3f4 137 Gene3D G3DSA:2.40.50.140 1 137 3.1E-63 T 28-03-2018 CO689_RS08060 638d34bd04bc07698300435fdaa2b3f4 137 PIRSF PIRSF002133 1 137 2.5E-48 T 28-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CO689_RS08060 638d34bd04bc07698300435fdaa2b3f4 137 ProSitePatterns PS00055 Ribosomal protein S12 signature. 56 63 - T 28-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CO689_RS02970 b4e38c3f1579841de940282150264023 179 SUPERFAMILY SSF53254 1 170 2.9E-29 T 28-03-2018 IPR029033 Histidine phosphatase superfamily CO689_RS02970 b4e38c3f1579841de940282150264023 179 Gene3D G3DSA:3.40.50.1240 1 173 2.4E-31 T 28-03-2018 IPR029033 Histidine phosphatase superfamily CO689_RS02970 b4e38c3f1579841de940282150264023 179 SMART SM00855 2 143 2.0E-5 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 CO689_RS02970 b4e38c3f1579841de940282150264023 179 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 3 158 1.6E-29 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 CO689_RS08005 4aa6025bc937e5e5df1beda036546e6a 47 Pfam PF00471 Ribosomal protein L33 2 47 2.5E-17 T 28-03-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CO689_RS08005 4aa6025bc937e5e5df1beda036546e6a 47 ProSitePatterns PS00582 Ribosomal protein L33 signature. 16 34 - T 28-03-2018 IPR018264 Ribosomal protein L33, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CO689_RS08005 4aa6025bc937e5e5df1beda036546e6a 47 SUPERFAMILY SSF57829 3 47 5.01E-14 T 28-03-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 CO689_RS08005 4aa6025bc937e5e5df1beda036546e6a 47 TIGRFAM TIGR01023 rpmG_bact: ribosomal protein bL33 3 47 1.6E-15 T 28-03-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CO689_RS08005 4aa6025bc937e5e5df1beda036546e6a 47 Hamap MF_00294 50S ribosomal protein L33 [rpmG]. 1 47 15.462 T 28-03-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CO689_RS09285 a03dc05f3570ccf7d9162988a1e24f76 102 TIGRFAM TIGR01563 gp16_SPP1: putative phage head-tail adaptor 5 96 1.8E-10 T 28-03-2018 IPR008767 Bacteriophage SPP1, head-tail adaptor CO689_RS09285 a03dc05f3570ccf7d9162988a1e24f76 102 Pfam PF05521 Phage head-tail joining protein 6 97 1.5E-17 T 28-03-2018 IPR008767 Bacteriophage SPP1, head-tail adaptor CO689_RS03130 b6a70d14baa7d780c0fd0fd1ebe398dd 92 PIRSF PIRSF002144 1 92 1.6E-32 T 28-03-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CO689_RS03130 b6a70d14baa7d780c0fd0fd1ebe398dd 92 Pfam PF00203 Ribosomal protein S19 3 83 3.7E-37 T 28-03-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CO689_RS03130 b6a70d14baa7d780c0fd0fd1ebe398dd 92 ProSitePatterns PS00323 Ribosomal protein S19 signature. 53 77 - T 28-03-2018 IPR020934 Ribosomal protein S19 conserved site GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CO689_RS03130 b6a70d14baa7d780c0fd0fd1ebe398dd 92 TIGRFAM TIGR01050 rpsS_bact: ribosomal protein uS19 1 92 1.2E-47 T 28-03-2018 IPR005732 Ribosomal protein S19, bacterial-type GO:0003735|GO:0006412|GO:0015935 CO689_RS03130 b6a70d14baa7d780c0fd0fd1ebe398dd 92 SUPERFAMILY SSF54570 3 84 3.4E-35 T 28-03-2018 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CO689_RS03130 b6a70d14baa7d780c0fd0fd1ebe398dd 92 Hamap MF_00531 30S ribosomal protein S19 [rpsS]. 1 89 25.56 T 28-03-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CO689_RS03130 b6a70d14baa7d780c0fd0fd1ebe398dd 92 Gene3D G3DSA:3.30.860.10 1 92 8.5E-41 T 28-03-2018 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CO689_RS03130 b6a70d14baa7d780c0fd0fd1ebe398dd 92 PRINTS PR00975 Ribosomal protein S19 family signature 65 80 2.2E-23 T 28-03-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CO689_RS03130 b6a70d14baa7d780c0fd0fd1ebe398dd 92 PRINTS PR00975 Ribosomal protein S19 family signature 53 65 2.2E-23 T 28-03-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CO689_RS03130 b6a70d14baa7d780c0fd0fd1ebe398dd 92 PRINTS PR00975 Ribosomal protein S19 family signature 33 52 2.2E-23 T 28-03-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CO689_RS04145 1a70cedb1497177c6c95916042042bfc 314 Gene3D G3DSA:3.40.190.10 21 185 1.4E-25 T 28-03-2018 CO689_RS04145 1a70cedb1497177c6c95916042042bfc 314 Gene3D G3DSA:3.40.190.10 186 308 1.1E-25 T 28-03-2018 CO689_RS04145 1a70cedb1497177c6c95916042042bfc 314 SUPERFAMILY SSF53850 35 305 2.75E-67 T 28-03-2018 CO689_RS04145 1a70cedb1497177c6c95916042042bfc 314 Pfam PF04069 Substrate binding domain of ABC-type glycine betaine transport system 35 302 1.3E-55 T 28-03-2018 IPR007210 ABC-type glycine betaine transport system, substrate-binding domain GO:0005215|GO:0006810 CO689_RS13195 cba400396936350ffa11e321e8094794 364 Gene3D G3DSA:3.40.1390.30 1 123 4.2E-35 T 28-03-2018 CO689_RS13195 cba400396936350ffa11e321e8094794 364 Gene3D G3DSA:3.40.1390.30 222 353 3.3E-11 T 28-03-2018 CO689_RS13195 cba400396936350ffa11e321e8094794 364 SUPERFAMILY SSF102705 1 363 2.22E-113 T 28-03-2018 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 CO689_RS13195 cba400396936350ffa11e321e8094794 364 PIRSF PIRSF037489 1 364 3.6E-129 T 28-03-2018 IPR017221 GTP cyclohydrolase 1 type 2//Nif3, bacteria CO689_RS13195 cba400396936350ffa11e321e8094794 364 Gene3D G3DSA:3.30.70.120 128 221 9.4E-31 T 28-03-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal CO689_RS13195 cba400396936350ffa11e321e8094794 364 TIGRFAM TIGR00486 YbgI_SA1388: dinuclear metal center protein, YbgI/SA1388 family 1 359 1.1E-65 T 28-03-2018 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 CO689_RS13195 cba400396936350ffa11e321e8094794 364 Pfam PF01784 NIF3 (NGG1p interacting factor 3) 5 345 9.7E-80 T 28-03-2018 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 CO689_RS06305 3a7afd8edf6fb2a97b609a42017eec60 251 Pfam PF01925 Sulfite exporter TauE/SafE 10 247 4.0E-34 T 28-03-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 CO689_RS05800 b2677c496467bc909704c9f0a9e3a2b8 333 Gene3D G3DSA:3.90.180.10 1 332 1.7E-75 T 28-03-2018 CO689_RS05800 b2677c496467bc909704c9f0a9e3a2b8 333 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 26 90 3.7E-12 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CO689_RS05800 b2677c496467bc909704c9f0a9e3a2b8 333 SUPERFAMILY SSF51735 116 296 1.78E-34 T 28-03-2018 IPR016040 NAD(P)-binding domain CO689_RS05800 b2677c496467bc909704c9f0a9e3a2b8 333 SMART SM00829 10 329 2.7E-14 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CO689_RS05800 b2677c496467bc909704c9f0a9e3a2b8 333 Pfam PF13602 Zinc-binding dehydrogenase 186 329 7.3E-32 T 28-03-2018 CO689_RS05800 b2677c496467bc909704c9f0a9e3a2b8 333 SUPERFAMILY SSF50129 4 149 6.54E-40 T 28-03-2018 IPR011032 GroES-like CO689_RS05375 22d6959904db97dd97e9bb8a21a74857 547 Gene3D G3DSA:3.40.50.970 1 193 2.8E-45 T 28-03-2018 CO689_RS05375 22d6959904db97dd97e9bb8a21a74857 547 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 4 176 1.7E-36 T 28-03-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 CO689_RS05375 22d6959904db97dd97e9bb8a21a74857 547 SUPERFAMILY SSF52518 3 177 9.48E-42 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CO689_RS05375 22d6959904db97dd97e9bb8a21a74857 547 PIRSF PIRSF036565 1 547 2.6E-202 T 28-03-2018 IPR012110 Thiamine pyrophosphate (TPP)-dependent enzyme GO:0016831 CO689_RS05375 22d6959904db97dd97e9bb8a21a74857 547 SUPERFAMILY SSF52518 353 544 8.11E-43 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CO689_RS05375 22d6959904db97dd97e9bb8a21a74857 547 Gene3D G3DSA:3.40.50.1220 194 334 2.2E-21 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CO689_RS05375 22d6959904db97dd97e9bb8a21a74857 547 SUPERFAMILY SSF52467 165 329 1.08E-29 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CO689_RS05375 22d6959904db97dd97e9bb8a21a74857 547 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 389 514 1.1E-16 T 28-03-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 CO689_RS05375 22d6959904db97dd97e9bb8a21a74857 547 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 196 317 5.3E-22 T 28-03-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 CO689_RS05375 22d6959904db97dd97e9bb8a21a74857 547 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 413 432 - T 28-03-2018 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 CO689_RS05375 22d6959904db97dd97e9bb8a21a74857 547 Gene3D G3DSA:3.40.50.970 335 540 1.6E-32 T 28-03-2018 CO689_RS12820 129bbe0e7ee02ed5c3371cd59d8ea4fa 223 Gene3D G3DSA:3.40.50.300 1 219 1.5E-48 T 28-03-2018 CO689_RS12820 129bbe0e7ee02ed5c3371cd59d8ea4fa 223 SUPERFAMILY SSF52540 1 216 7.96E-41 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CO689_RS12820 129bbe0e7ee02ed5c3371cd59d8ea4fa 223 Pfam PF02224 Cytidylate kinase 6 215 1.2E-66 T 28-03-2018 IPR011994 Cytidylate kinase domain GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 CO689_RS12820 129bbe0e7ee02ed5c3371cd59d8ea4fa 223 Hamap MF_00238 Cytidylate kinase [cmk]. 4 219 31.181 T 28-03-2018 IPR003136 Cytidylate kinase GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 CO689_RS12820 129bbe0e7ee02ed5c3371cd59d8ea4fa 223 TIGRFAM TIGR00017 cmk: cytidylate kinase 4 212 7.2E-68 T 28-03-2018 IPR003136 Cytidylate kinase GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 CO689_RS13610 a766b8bf443a04ae6b72e45f946231c8 220 Pfam PF08241 Methyltransferase domain 40 132 8.9E-22 T 28-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 CO689_RS13610 a766b8bf443a04ae6b72e45f946231c8 220 Gene3D G3DSA:3.40.50.150 2 207 1.1E-28 T 28-03-2018 CO689_RS13610 a766b8bf443a04ae6b72e45f946231c8 220 SUPERFAMILY SSF53335 8 165 7.15E-35 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CO689_RS10575 ba009c367f1f3411c46daa4365926049 420 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 85 231 2.7E-33 T 28-03-2018 IPR004474 Cell envelope-related transcriptional attenuator domain CO689_RS10575 ba009c367f1f3411c46daa4365926049 420 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 85 232 1.8E-40 T 28-03-2018 IPR004474 Cell envelope-related transcriptional attenuator domain CO689_RS10575 ba009c367f1f3411c46daa4365926049 420 Gene3D G3DSA:2.130.10.10 27 418 8.7E-4 T 28-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 CO689_RS10440 060b674ce4e3e7fe50232550732a2be1 293 Gene3D G3DSA:3.40.50.1980 131 291 1.1E-32 T 28-03-2018 CO689_RS10440 060b674ce4e3e7fe50232550732a2be1 293 TIGRFAM TIGR03659 IsdE: heme ABC transporter, heme-binding protein isdE 9 290 4.7E-117 T 28-03-2018 IPR019957 ABC transporter, high-affinity heme uptake system protein IsdE GO:0015886|GO:0016020|GO:0020037 CO689_RS10440 060b674ce4e3e7fe50232550732a2be1 293 Pfam PF01497 Periplasmic binding protein 39 268 7.6E-40 T 28-03-2018 IPR002491 ABC transporter periplasmic binding domain GO:0005488 CO689_RS10440 060b674ce4e3e7fe50232550732a2be1 293 SUPERFAMILY SSF53807 38 290 3.81E-48 T 28-03-2018 CO689_RS10440 060b674ce4e3e7fe50232550732a2be1 293 Gene3D G3DSA:3.40.50.1980 26 130 2.0E-13 T 28-03-2018 CO689_RS00710 3efacb3d9c51e55f98501f80f69879d7 268 Pfam PF13614 AAA domain 1 177 9.0E-35 T 28-03-2018 IPR025669 AAA domain CO689_RS00710 3efacb3d9c51e55f98501f80f69879d7 268 Gene3D G3DSA:3.40.50.300 2 268 3.2E-41 T 28-03-2018 CO689_RS00710 3efacb3d9c51e55f98501f80f69879d7 268 SUPERFAMILY SSF52540 1 260 4.9E-35 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CO689_RS00130 3efacb3d9c51e55f98501f80f69879d7 268 Pfam PF13614 AAA domain 1 177 9.0E-35 T 28-03-2018 IPR025669 AAA domain CO689_RS00130 3efacb3d9c51e55f98501f80f69879d7 268 Gene3D G3DSA:3.40.50.300 2 268 3.2E-41 T 28-03-2018 CO689_RS00130 3efacb3d9c51e55f98501f80f69879d7 268 SUPERFAMILY SSF52540 1 260 4.9E-35 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CO689_RS00770 3efacb3d9c51e55f98501f80f69879d7 268 Pfam PF13614 AAA domain 1 177 9.0E-35 T 28-03-2018 IPR025669 AAA domain CO689_RS00770 3efacb3d9c51e55f98501f80f69879d7 268 Gene3D G3DSA:3.40.50.300 2 268 3.2E-41 T 28-03-2018 CO689_RS00770 3efacb3d9c51e55f98501f80f69879d7 268 SUPERFAMILY SSF52540 1 260 4.9E-35 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CO689_RS11820 7c3b8705491d15e548e817d3e3e627f5 240 SUPERFAMILY SSF46785 4 69 1.36E-5 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS11820 7c3b8705491d15e548e817d3e3e627f5 240 SMART SM00866 91 230 7.3E-18 T 28-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 CO689_RS11820 7c3b8705491d15e548e817d3e3e627f5 240 Gene3D G3DSA:1.10.10.10 1 68 1.4E-6 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS11820 7c3b8705491d15e548e817d3e3e627f5 240 SUPERFAMILY SSF64288 72 235 2.36E-29 T 28-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain CO689_RS11820 7c3b8705491d15e548e817d3e3e627f5 240 Pfam PF07702 UTRA domain 92 227 4.3E-24 T 28-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 CO689_RS11820 7c3b8705491d15e548e817d3e3e627f5 240 Gene3D G3DSA:3.40.1410.10 69 236 2.8E-25 T 28-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain CO689_RS06495 4069edff9c34cb0c4438a2bd23fd023b 202 Pfam PF03848 Tellurite resistance protein TehB 28 122 2.3E-9 T 28-03-2018 IPR015985 Tellurite resistance methyltransferase TehB-like domain CO689_RS06495 4069edff9c34cb0c4438a2bd23fd023b 202 SUPERFAMILY SSF53335 2 181 1.85E-22 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CO689_RS06495 4069edff9c34cb0c4438a2bd23fd023b 202 Gene3D G3DSA:3.40.50.150 1 198 2.3E-11 T 28-03-2018 CO689_RS04025 e7c29c3f59edfea0f199ebfe0ec6c78f 372 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 136 145 2.0E-6 T 28-03-2018 CO689_RS04025 e7c29c3f59edfea0f199ebfe0ec6c78f 372 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 169 194 2.0E-6 T 28-03-2018 CO689_RS04025 e7c29c3f59edfea0f199ebfe0ec6c78f 372 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 5 27 2.0E-6 T 28-03-2018 CO689_RS04025 e7c29c3f59edfea0f199ebfe0ec6c78f 372 Pfam PF13738 Pyridine nucleotide-disulphide oxidoreductase 8 310 4.7E-95 T 28-03-2018 CO689_RS04025 e7c29c3f59edfea0f199ebfe0ec6c78f 372 Gene3D G3DSA:3.50.50.60 182 372 3.4E-20 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CO689_RS04025 e7c29c3f59edfea0f199ebfe0ec6c78f 372 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 169 187 5.1E-7 T 28-03-2018 CO689_RS04025 e7c29c3f59edfea0f199ebfe0ec6c78f 372 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 291 313 5.1E-7 T 28-03-2018 CO689_RS04025 e7c29c3f59edfea0f199ebfe0ec6c78f 372 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 5.1E-7 T 28-03-2018 CO689_RS04025 e7c29c3f59edfea0f199ebfe0ec6c78f 372 SUPERFAMILY SSF51905 1 260 1.59E-26 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CO689_RS04025 e7c29c3f59edfea0f199ebfe0ec6c78f 372 Gene3D G3DSA:3.50.50.60 1 181 6.5E-17 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CO689_RS05660 7af531298ee40a80c854642d4246854e 417 SUPERFAMILY SSF52777 186 417 5.34E-63 T 28-03-2018 CO689_RS05660 7af531298ee40a80c854642d4246854e 417 Gene3D G3DSA:2.40.50.100 5 79 1.6E-19 T 28-03-2018 CO689_RS05660 7af531298ee40a80c854642d4246854e 417 SUPERFAMILY SSF47005 120 167 2.09E-11 T 28-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CO689_RS05660 7af531298ee40a80c854642d4246854e 417 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 192 416 2.5E-67 T 28-03-2018 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CO689_RS05660 7af531298ee40a80c854642d4246854e 417 Pfam PF00364 Biotin-requiring enzyme 4 76 2.5E-16 T 28-03-2018 IPR000089 Biotin/lipoyl attachment CO689_RS05660 7af531298ee40a80c854642d4246854e 417 Pfam PF02817 e3 binding domain 127 162 5.4E-12 T 28-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CO689_RS05660 7af531298ee40a80c854642d4246854e 417 Gene3D G3DSA:4.10.320.10 118 178 7.2E-16 T 28-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CO689_RS05660 7af531298ee40a80c854642d4246854e 417 Gene3D G3DSA:3.30.559.10 179 417 4.7E-65 T 28-03-2018 CO689_RS05660 7af531298ee40a80c854642d4246854e 417 SUPERFAMILY SSF51230 1 93 4.84E-24 T 28-03-2018 IPR011053 Single hybrid motif CO689_RS07630 3199e0ad82f51c729e969d728beffa2a 133 SUPERFAMILY SSF54001 46 130 4.22E-14 T 28-03-2018 CO689_RS07630 3199e0ad82f51c729e969d728beffa2a 133 Pfam PF05257 CHAP domain 47 109 4.5E-9 T 28-03-2018 IPR007921 CHAP domain CO689_RS02850 96526accd2fb831ec9145af2432806bd 329 SUPERFAMILY SSF53807 43 319 1.02E-57 T 28-03-2018 CO689_RS02850 96526accd2fb831ec9145af2432806bd 329 Gene3D G3DSA:3.40.50.1980 28 157 9.6E-30 T 28-03-2018 CO689_RS02850 96526accd2fb831ec9145af2432806bd 329 Gene3D G3DSA:3.40.50.1980 158 328 6.6E-29 T 28-03-2018 CO689_RS02850 96526accd2fb831ec9145af2432806bd 329 Pfam PF01497 Periplasmic binding protein 60 300 5.7E-31 T 28-03-2018 IPR002491 ABC transporter periplasmic binding domain GO:0005488 CO689_RS05640 90edebce4c0902be9ad9797378cc5bc4 560 Pfam PF09848 Uncharacterized conserved protein (DUF2075) 184 542 7.9E-105 T 28-03-2018 IPR018647 Domain of unknown function DUF2075 CO689_RS05640 90edebce4c0902be9ad9797378cc5bc4 560 SUPERFAMILY SSF52540 108 228 2.13E-14 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CO689_RS05640 90edebce4c0902be9ad9797378cc5bc4 560 SUPERFAMILY SSF52540 260 318 2.13E-14 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CO689_RS05640 90edebce4c0902be9ad9797378cc5bc4 560 Gene3D G3DSA:3.40.50.300 151 364 2.2E-18 T 28-03-2018 CO689_RS05640 90edebce4c0902be9ad9797378cc5bc4 560 Gene3D G3DSA:3.40.1440.10 5 139 3.8E-7 T 28-03-2018 IPR000305 GIY-YIG nuclease superfamily CO689_RS05260 06a87bf2671d157c9762e620c1355575 296 Hamap MF_00729 Fructose-bisphosphate aldolase class 1 [fda]. 2 293 51.904 T 28-03-2018 IPR023014 Fructose-bisphosphate aldolase class I, Gram positive bacteria-type GO:0004332|GO:0006096 KEGG: 00010+4.1.2.13|KEGG: 00030+4.1.2.13|KEGG: 00051+4.1.2.13|KEGG: 00680+4.1.2.13|KEGG: 00710+4.1.2.13|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 CO689_RS05260 06a87bf2671d157c9762e620c1355575 296 SUPERFAMILY SSF51569 4 296 7.12E-96 T 28-03-2018 CO689_RS05260 06a87bf2671d157c9762e620c1355575 296 Pfam PF00274 Fructose-bisphosphate aldolase class-I 9 212 1.9E-11 T 28-03-2018 IPR000741 Fructose-bisphosphate aldolase, class-I GO:0004332|GO:0006096 KEGG: 00010+4.1.2.13|KEGG: 00030+4.1.2.13|KEGG: 00051+4.1.2.13|KEGG: 00680+4.1.2.13|KEGG: 00710+4.1.2.13|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CO689_RS05260 06a87bf2671d157c9762e620c1355575 296 Gene3D G3DSA:3.20.20.70 1 293 8.3E-72 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CO689_RS12960 338e34b3d4cab0ce445d38d3bb38ee38 327 SUPERFAMILY SSF52518 3 193 3.59E-68 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CO689_RS12960 338e34b3d4cab0ce445d38d3bb38ee38 327 Gene3D G3DSA:3.40.50.920 195 326 9.4E-33 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CO689_RS12960 338e34b3d4cab0ce445d38d3bb38ee38 327 Pfam PF02780 Transketolase, C-terminal domain 194 317 1.1E-39 T 28-03-2018 IPR033248 Transketolase, C-terminal domain CO689_RS12960 338e34b3d4cab0ce445d38d3bb38ee38 327 Gene3D G3DSA:3.40.50.970 1 194 1.5E-65 T 28-03-2018 CO689_RS12960 338e34b3d4cab0ce445d38d3bb38ee38 327 Pfam PF02779 Transketolase, pyrimidine binding domain 4 178 5.2E-45 T 28-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain CO689_RS12960 338e34b3d4cab0ce445d38d3bb38ee38 327 SUPERFAMILY SSF52922 189 324 1.57E-39 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CO689_RS12960 338e34b3d4cab0ce445d38d3bb38ee38 327 SMART SM00861 4 179 9.2E-62 T 28-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain CO689_RS07250 8774e670fae08b9543449f828874fc6a 513 PRINTS PR00096 Glutamine amidotransferase superfamily signature 168 181 1.1E-7 T 28-03-2018 CO689_RS07250 8774e670fae08b9543449f828874fc6a 513 PRINTS PR00096 Glutamine amidotransferase superfamily signature 54 63 1.1E-7 T 28-03-2018 CO689_RS07250 8774e670fae08b9543449f828874fc6a 513 PRINTS PR00096 Glutamine amidotransferase superfamily signature 81 92 1.1E-7 T 28-03-2018 CO689_RS07250 8774e670fae08b9543449f828874fc6a 513 SUPERFAMILY SSF52402 188 406 1.65E-62 T 28-03-2018 CO689_RS07250 8774e670fae08b9543449f828874fc6a 513 TIGRFAM TIGR00884 guaA_Cterm: GMP synthase (glutamine-hydrolyzing), C-terminal domain 203 513 6.2E-154 T 28-03-2018 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 CO689_RS07250 8774e670fae08b9543449f828874fc6a 513 SUPERFAMILY SSF52317 8 228 4.77E-57 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CO689_RS07250 8774e670fae08b9543449f828874fc6a 513 Pfam PF00958 GMP synthase C terminal domain 422 512 6.8E-43 T 28-03-2018 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 CO689_RS07250 8774e670fae08b9543449f828874fc6a 513 Hamap MF_00344 GMP synthase [glutamine-hydrolyzing] [guaA]. 7 513 55.058 T 28-03-2018 IPR022955 GMP synthase GO:0003922|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221 CO689_RS07250 8774e670fae08b9543449f828874fc6a 513 TIGRFAM TIGR00888 guaA_Nterm: GMP synthase (glutamine-hydrolyzing), N-terminal domain 10 195 1.9E-82 T 28-03-2018 IPR004739 GMP synthase, glutamine amidotransferase GO:0003922|GO:0005524|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 CO689_RS07250 8774e670fae08b9543449f828874fc6a 513 Gene3D G3DSA:3.30.300.10 389 513 9.8E-53 T 28-03-2018 CO689_RS07250 8774e670fae08b9543449f828874fc6a 513 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 10 24 1.7E-6 T 28-03-2018 CO689_RS07250 8774e670fae08b9543449f828874fc6a 513 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 81 97 1.7E-6 T 28-03-2018 CO689_RS07250 8774e670fae08b9543449f828874fc6a 513 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 51 65 1.7E-6 T 28-03-2018 CO689_RS07250 8774e670fae08b9543449f828874fc6a 513 Pfam PF03054 tRNA methyl transferase 220 249 2.0E-5 T 28-03-2018 CO689_RS07250 8774e670fae08b9543449f828874fc6a 513 Gene3D G3DSA:3.40.50.880 5 222 6.9E-54 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CO689_RS07250 8774e670fae08b9543449f828874fc6a 513 SUPERFAMILY SSF54810 393 513 4.97E-50 T 28-03-2018 CO689_RS07250 8774e670fae08b9543449f828874fc6a 513 PRINTS PR00097 Anthranilate synthase component II signature 168 181 5.2E-6 T 28-03-2018 CO689_RS07250 8774e670fae08b9543449f828874fc6a 513 PRINTS PR00097 Anthranilate synthase component II signature 54 63 5.2E-6 T 28-03-2018 CO689_RS07250 8774e670fae08b9543449f828874fc6a 513 PRINTS PR00097 Anthranilate synthase component II signature 81 92 5.2E-6 T 28-03-2018 CO689_RS07250 8774e670fae08b9543449f828874fc6a 513 Pfam PF00117 Glutamine amidotransferase class-I 12 190 3.4E-44 T 28-03-2018 IPR017926 Glutamine amidotransferase CO689_RS07250 8774e670fae08b9543449f828874fc6a 513 Gene3D G3DSA:3.40.50.620 223 381 3.1E-31 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CO689_RS10005 f56b155b060b62bbfeb276d6f90a5694 142 TIGRFAM TIGR00943 2a6301s02: monovalent cation:proton antiporter 28 134 1.0E-41 T 28-03-2018 IPR005281 Monovalent cation:proton antiporter, subunit B GO:0006812|GO:0008324|GO:0016021 CO689_RS10005 f56b155b060b62bbfeb276d6f90a5694 142 Pfam PF04039 Domain related to MnhB subunit of Na+/H+ antiporter 10 133 2.3E-30 T 28-03-2018 IPR007182 Na+/H+ antiporter MnhB subunit-related protein CO689_RS00565 e9c4e4498ac7be0a68b04a1cfb189be6 202 Pfam PF02796 Helix-turn-helix domain of resolvase 147 199 4.1E-20 T 28-03-2018 IPR006120 Resolvase, HTH domain GO:0000150|GO:0003677|GO:0006310 CO689_RS00565 e9c4e4498ac7be0a68b04a1cfb189be6 202 Pfam PF00239 Resolvase, N terminal domain 2 145 1.1E-32 T 28-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CO689_RS00565 e9c4e4498ac7be0a68b04a1cfb189be6 202 SMART SM00857 2 145 3.8E-42 T 28-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CO689_RS00565 e9c4e4498ac7be0a68b04a1cfb189be6 202 SUPERFAMILY SSF46689 165 197 3.94E-5 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CO689_RS00565 e9c4e4498ac7be0a68b04a1cfb189be6 202 Gene3D G3DSA:1.20.5.40 115 143 2.4E-9 T 28-03-2018 CO689_RS00565 e9c4e4498ac7be0a68b04a1cfb189be6 202 Gene3D G3DSA:1.10.10.60 146 201 1.4E-13 T 28-03-2018 CO689_RS00565 e9c4e4498ac7be0a68b04a1cfb189be6 202 Gene3D G3DSA:3.40.50.1390 1 114 7.3E-30 T 28-03-2018 CO689_RS00565 e9c4e4498ac7be0a68b04a1cfb189be6 202 ProSitePatterns PS00398 Site-specific recombinases signature 2. 56 68 - T 28-03-2018 IPR006118 Recombinase, conserved site GO:0000150|GO:0006310 CO689_RS00565 e9c4e4498ac7be0a68b04a1cfb189be6 202 ProSitePatterns PS00397 Site-specific recombinases active site. 5 13 - T 28-03-2018 IPR006118 Recombinase, conserved site GO:0000150|GO:0006310 CO689_RS00565 e9c4e4498ac7be0a68b04a1cfb189be6 202 SUPERFAMILY SSF53041 1 145 7.72E-36 T 28-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CO689_RS03970 f6f4e84c1a9705e1a979af317fa48f39 317 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 8 217 2.3E-45 T 28-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CO689_RS03970 f6f4e84c1a9705e1a979af317fa48f39 317 ProSitePatterns PS00840 Uroporphyrin-III C-methyltransferase signature 2. 87 120 - T 28-03-2018 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 CO689_RS03970 f6f4e84c1a9705e1a979af317fa48f39 317 Gene3D G3DSA:3.30.950.10 133 254 4.7E-23 T 28-03-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CO689_RS03970 f6f4e84c1a9705e1a979af317fa48f39 317 TIGRFAM TIGR01469 cobA_cysG_Cterm: uroporphyrinogen-III C-methyltransferase 7 241 1.8E-78 T 28-03-2018 IPR006366 Uroporphyrin-III C-methyltransferase GO:0006779|GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 CO689_RS03970 f6f4e84c1a9705e1a979af317fa48f39 317 Gene3D G3DSA:3.40.1010.10 6 132 4.4E-33 T 28-03-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CO689_RS03970 f6f4e84c1a9705e1a979af317fa48f39 317 SUPERFAMILY SSF53790 5 250 1.11E-64 T 28-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CO689_RS00465 f4384edead9129712c2c7e7de40089ec 499 Gene3D G3DSA:3.50.50.60 1 442 1.6E-16 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CO689_RS00465 f4384edead9129712c2c7e7de40089ec 499 SUPERFAMILY SSF51905 4 274 1.37E-21 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CO689_RS00465 f4384edead9129712c2c7e7de40089ec 499 Pfam PF06039 Malate:quinone oxidoreductase (Mqo) 7 492 3.4E-213 T 28-03-2018 IPR006231 Malate:quinone-oxidoreductase GO:0006099|GO:0008924 KEGG: 00020+1.1.5.4|KEGG: 00620+1.1.5.4|MetaCyc: PWY-7254 CO689_RS00465 f4384edead9129712c2c7e7de40089ec 499 Hamap MF_00212 Probable malate:quinone oxidoreductase [mqo]. 3 492 50.701 T 28-03-2018 IPR006231 Malate:quinone-oxidoreductase GO:0006099|GO:0008924 KEGG: 00020+1.1.5.4|KEGG: 00620+1.1.5.4|MetaCyc: PWY-7254 CO689_RS00465 f4384edead9129712c2c7e7de40089ec 499 TIGRFAM TIGR01320 mal_quin_oxido: malate dehydrogenase (acceptor) 9 489 2.5E-186 T 28-03-2018 IPR006231 Malate:quinone-oxidoreductase GO:0006099|GO:0008924 KEGG: 00020+1.1.5.4|KEGG: 00620+1.1.5.4|MetaCyc: PWY-7254 CO689_RS04215 a3bfa7617c2bc0b7b055aedc365e95a5 417 Gene3D G3DSA:3.40.630.10 1 185 5.3E-33 T 28-03-2018 CO689_RS04215 a3bfa7617c2bc0b7b055aedc365e95a5 417 SUPERFAMILY SSF55031 200 294 1.03E-9 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain CO689_RS04215 a3bfa7617c2bc0b7b055aedc365e95a5 417 TIGRFAM TIGR01910 DapE-ArgE: peptidase, ArgE/DapE family 7 396 2.5E-96 T 28-03-2018 IPR010182 N-formyl-4-amino-5-aminomethyl-2-methylpyrimidine deformylase/Succinyl-diaminopimelate desuccinylase CO689_RS04215 a3bfa7617c2bc0b7b055aedc365e95a5 417 Pfam PF01546 Peptidase family M20/M25/M40 70 402 2.2E-31 T 28-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CO689_RS04215 a3bfa7617c2bc0b7b055aedc365e95a5 417 Pfam PF07687 Peptidase dimerisation domain 173 294 1.0E-24 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain CO689_RS04215 a3bfa7617c2bc0b7b055aedc365e95a5 417 SUPERFAMILY SSF53187 322 405 4.86E-54 T 28-03-2018 CO689_RS04215 a3bfa7617c2bc0b7b055aedc365e95a5 417 SUPERFAMILY SSF53187 4 182 4.86E-54 T 28-03-2018 CO689_RS04215 a3bfa7617c2bc0b7b055aedc365e95a5 417 Gene3D G3DSA:3.40.630.10 301 404 0.013 T 28-03-2018 CO689_RS04215 a3bfa7617c2bc0b7b055aedc365e95a5 417 Gene3D G3DSA:3.30.70.360 186 300 4.5E-20 T 28-03-2018 CO689_RS03380 85a59ee0fd927ab22ffbf4237a851f48 308 Pfam PF01497 Periplasmic binding protein 52 280 1.3E-29 T 28-03-2018 IPR002491 ABC transporter periplasmic binding domain GO:0005488 CO689_RS03380 85a59ee0fd927ab22ffbf4237a851f48 308 SUPERFAMILY SSF53807 35 298 3.02E-51 T 28-03-2018 CO689_RS03380 85a59ee0fd927ab22ffbf4237a851f48 308 Gene3D G3DSA:3.40.50.1980 149 307 5.9E-27 T 28-03-2018 CO689_RS03380 85a59ee0fd927ab22ffbf4237a851f48 308 Gene3D G3DSA:3.40.50.1980 31 148 3.7E-21 T 28-03-2018 CO689_RS06165 73aea5d877d4b505865f064db4449f27 424 SUPERFAMILY SSF116734 230 423 3.43E-33 T 28-03-2018 CO689_RS06165 73aea5d877d4b505865f064db4449f27 424 Gene3D G3DSA:3.90.220.20 4 178 3.6E-35 T 28-03-2018 CO689_RS06165 73aea5d877d4b505865f064db4449f27 424 SUPERFAMILY SSF116734 6 226 4.74E-51 T 28-03-2018 CO689_RS06165 73aea5d877d4b505865f064db4449f27 424 Gene3D G3DSA:3.90.220.20 194 409 1.5E-38 T 28-03-2018 CO689_RS06165 73aea5d877d4b505865f064db4449f27 424 Pfam PF01420 Type I restriction modification DNA specificity domain 252 405 4.5E-16 T 28-03-2018 IPR000055 Restriction endonuclease, type I, HsdS GO:0003677|GO:0006304 CO689_RS06165 73aea5d877d4b505865f064db4449f27 424 Pfam PF01420 Type I restriction modification DNA specificity domain 22 203 5.4E-18 T 28-03-2018 IPR000055 Restriction endonuclease, type I, HsdS GO:0003677|GO:0006304 CO689_RS07900 43dbda5aa08bc4ca1bd73cd2bc3fa6d1 379 Pfam PF07690 Major Facilitator Superfamily 2 305 1.1E-38 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CO689_RS07900 43dbda5aa08bc4ca1bd73cd2bc3fa6d1 379 Gene3D G3DSA:1.20.1250.20 1 187 7.6E-32 T 28-03-2018 CO689_RS07900 43dbda5aa08bc4ca1bd73cd2bc3fa6d1 379 Gene3D G3DSA:1.20.1250.20 188 376 9.9E-18 T 28-03-2018 CO689_RS07900 43dbda5aa08bc4ca1bd73cd2bc3fa6d1 379 SUPERFAMILY SSF103473 2 370 1.07E-56 T 28-03-2018 IPR020846 Major facilitator superfamily domain CO689_RS01705 4fb671dd60df9034ad10db399046f148 154 Gene3D G3DSA:3.40.50.2300 1 153 1.3E-45 T 28-03-2018 CO689_RS01705 4fb671dd60df9034ad10db399046f148 154 SUPERFAMILY SSF52788 1 145 3.27E-41 T 28-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily CO689_RS01705 4fb671dd60df9034ad10db399046f148 154 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 78 93 1.7E-17 T 28-03-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 CO689_RS01705 4fb671dd60df9034ad10db399046f148 154 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 4 21 1.7E-17 T 28-03-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 CO689_RS01705 4fb671dd60df9034ad10db399046f148 154 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 46 62 1.7E-17 T 28-03-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 CO689_RS01705 4fb671dd60df9034ad10db399046f148 154 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 118 133 1.7E-17 T 28-03-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 CO689_RS01705 4fb671dd60df9034ad10db399046f148 154 SMART SM00226 2 144 2.0E-38 T 28-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily CO689_RS01705 4fb671dd60df9034ad10db399046f148 154 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 4 141 8.4E-35 T 28-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily CO689_RS09445 a4fb824aca7953575595f2b701e005d0 106 SUPERFAMILY SSF52833 4 103 1.5E-27 T 28-03-2018 IPR012336 Thioredoxin-like fold CO689_RS09445 a4fb824aca7953575595f2b701e005d0 106 Gene3D G3DSA:3.40.30.10 1 106 3.5E-24 T 28-03-2018 CO689_RS09445 a4fb824aca7953575595f2b701e005d0 106 Pfam PF00085 Thioredoxin 5 101 1.3E-19 T 28-03-2018 IPR013766 Thioredoxin domain GO:0045454 CO689_RS11080 fc538f90df4bc345dfbefd5ed6947d81 782 Pfam PF00488 MutS domain V 332 512 2.2E-34 T 28-03-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 CO689_RS11080 fc538f90df4bc345dfbefd5ed6947d81 782 Pfam PF01713 Smr domain 707 782 2.1E-20 T 28-03-2018 IPR002625 Smr domain CO689_RS11080 fc538f90df4bc345dfbefd5ed6947d81 782 ProSitePatterns PS00486 DNA mismatch repair proteins mutS family signature. 411 427 - T 28-03-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 CO689_RS11080 fc538f90df4bc345dfbefd5ed6947d81 782 Gene3D G3DSA:3.40.50.300 293 557 6.7E-36 T 28-03-2018 CO689_RS11080 fc538f90df4bc345dfbefd5ed6947d81 782 SMART SM00533 9 316 7.2E-8 T 28-03-2018 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 CO689_RS11080 fc538f90df4bc345dfbefd5ed6947d81 782 SUPERFAMILY SSF48334 34 287 5.89E-18 T 28-03-2018 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 CO689_RS11080 fc538f90df4bc345dfbefd5ed6947d81 782 SUPERFAMILY SSF52540 294 518 4.6E-43 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CO689_RS11080 fc538f90df4bc345dfbefd5ed6947d81 782 SUPERFAMILY SSF160443 705 781 4.32E-11 T 28-03-2018 IPR002625 Smr domain CO689_RS11080 fc538f90df4bc345dfbefd5ed6947d81 782 SMART SM00463 704 782 4.7E-24 T 28-03-2018 IPR002625 Smr domain CO689_RS11080 fc538f90df4bc345dfbefd5ed6947d81 782 Hamap MF_00092 Endonuclease MutS2 [mutS2]. 2 781 21.146 T 28-03-2018 IPR005747 Endonuclease MutS2 GO:0004519|GO:0016887|GO:0030983|GO:0045910 CO689_RS11080 fc538f90df4bc345dfbefd5ed6947d81 782 TIGRFAM TIGR01069 mutS2: MutS2 family protein 2 782 1.7E-233 T 28-03-2018 IPR005747 Endonuclease MutS2 GO:0004519|GO:0016887|GO:0030983|GO:0045910 CO689_RS11080 fc538f90df4bc345dfbefd5ed6947d81 782 PIRSF PIRSF005814 1 782 2.5E-271 T 28-03-2018 IPR005747 Endonuclease MutS2 GO:0004519|GO:0016887|GO:0030983|GO:0045910 CO689_RS11080 fc538f90df4bc345dfbefd5ed6947d81 782 SMART SM00534 329 514 2.9E-80 T 28-03-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 CO689_RS07795 b5282d5e24ce06ca3ee4040d88fdd043 123 TIGRFAM TIGR00526 folB_dom: FolB domain 3 121 1.7E-32 T 28-03-2018 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 CO689_RS07795 b5282d5e24ce06ca3ee4040d88fdd043 123 TIGRFAM TIGR00525 folB: dihydroneopterin aldolase 3 118 4.0E-38 T 28-03-2018 IPR006156 Dihydroneopterin aldolase GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 CO689_RS07795 b5282d5e24ce06ca3ee4040d88fdd043 123 SMART SM00905 5 118 2.7E-47 T 28-03-2018 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 CO689_RS07795 b5282d5e24ce06ca3ee4040d88fdd043 123 Gene3D G3DSA:3.30.1130.10 2 120 3.0E-32 T 28-03-2018 CO689_RS07795 b5282d5e24ce06ca3ee4040d88fdd043 123 SUPERFAMILY SSF55620 1 120 2.4E-40 T 28-03-2018 CO689_RS07795 b5282d5e24ce06ca3ee4040d88fdd043 123 Pfam PF02152 Dihydroneopterin aldolase 5 117 2.2E-32 T 28-03-2018 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 CO689_RS02345 1165742038c601f0d6663f3d44d95b72 68 SUPERFAMILY SSF55008 1 67 2.49E-16 T 28-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 CO689_RS02345 1165742038c601f0d6663f3d44d95b72 68 PRINTS PR00944 Copper ion binding protein signature 53 66 2.3E-5 T 28-03-2018 IPR000428 Copper ion binding protein GO:0005507|GO:0006825 CO689_RS02345 1165742038c601f0d6663f3d44d95b72 68 PRINTS PR00944 Copper ion binding protein signature 2 14 2.3E-5 T 28-03-2018 IPR000428 Copper ion binding protein GO:0005507|GO:0006825 CO689_RS02345 1165742038c601f0d6663f3d44d95b72 68 PRINTS PR00944 Copper ion binding protein signature 14 27 2.3E-5 T 28-03-2018 IPR000428 Copper ion binding protein GO:0005507|GO:0006825 CO689_RS02345 1165742038c601f0d6663f3d44d95b72 68 Gene3D G3DSA:3.30.70.100 1 67 4.5E-17 T 28-03-2018 CO689_RS02345 1165742038c601f0d6663f3d44d95b72 68 TIGRFAM TIGR00003 TIGR00003: copper ion binding protein 3 67 8.0E-19 T 28-03-2018 IPR006122 Heavy metal-associated domain, copper ion-binding GO:0005507 Reactome: R-HSA-936837 CO689_RS02345 1165742038c601f0d6663f3d44d95b72 68 Pfam PF00403 Heavy-metal-associated domain 5 65 1.7E-14 T 28-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 CO689_RS02090 a667576e3ab7a1837e14d827aede2be0 94 Gene3D G3DSA:2.30.33.40 1 94 9.6E-36 T 28-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 CO689_RS02090 a667576e3ab7a1837e14d827aede2be0 94 SMART SM00883 1 93 6.9E-49 T 28-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 CO689_RS02090 a667576e3ab7a1837e14d827aede2be0 94 Pfam PF00166 Chaperonin 10 Kd subunit 2 93 1.2E-32 T 28-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 CO689_RS02090 a667576e3ab7a1837e14d827aede2be0 94 SUPERFAMILY SSF50129 1 93 4.59E-31 T 28-03-2018 IPR011032 GroES-like CO689_RS02090 a667576e3ab7a1837e14d827aede2be0 94 PRINTS PR00297 10kDa chaperonin signature 24 45 8.1E-29 T 28-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 CO689_RS02090 a667576e3ab7a1837e14d827aede2be0 94 PRINTS PR00297 10kDa chaperonin signature 59 71 8.1E-29 T 28-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 CO689_RS02090 a667576e3ab7a1837e14d827aede2be0 94 PRINTS PR00297 10kDa chaperonin signature 80 93 8.1E-29 T 28-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 CO689_RS02090 a667576e3ab7a1837e14d827aede2be0 94 PRINTS PR00297 10kDa chaperonin signature 2 17 8.1E-29 T 28-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 CO689_RS02090 a667576e3ab7a1837e14d827aede2be0 94 ProSitePatterns PS00681 Chaperonins cpn10 signature. 2 26 - T 28-03-2018 IPR018369 Chaperonin GroES, conserved site GO:0005524|GO:0006457 CO689_RS02090 a667576e3ab7a1837e14d827aede2be0 94 Hamap MF_00580 10 kDa chaperonin [groS]. 1 94 24.34 T 28-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 CO689_RS05380 5468c208932f08d9b1f455789e360499 151 Gene3D G3DSA:1.10.10.10 3 126 1.2E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS05380 5468c208932f08d9b1f455789e360499 151 SUPERFAMILY SSF46785 11 125 1.02E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS05380 5468c208932f08d9b1f455789e360499 151 SMART SM00347 26 126 1.3E-4 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CO689_RS05380 5468c208932f08d9b1f455789e360499 151 Pfam PF12802 MarR family 32 89 5.2E-11 T 28-03-2018 CO689_RS06275 379dca8289d4fb6ab6b7398f3b879d0f 460 Gene3D G3DSA:3.40.309.10 249 441 2.0E-65 T 28-03-2018 CO689_RS06275 379dca8289d4fb6ab6b7398f3b879d0f 460 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 258 269 - T 28-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 CO689_RS06275 379dca8289d4fb6ab6b7398f3b879d0f 460 Gene3D G3DSA:3.40.605.10 1 248 5.6E-87 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CO689_RS06275 379dca8289d4fb6ab6b7398f3b879d0f 460 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 230 237 - T 28-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 CO689_RS06275 379dca8289d4fb6ab6b7398f3b879d0f 460 Pfam PF00171 Aldehyde dehydrogenase family 3 454 1.2E-157 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CO689_RS06275 379dca8289d4fb6ab6b7398f3b879d0f 460 SUPERFAMILY SSF53720 4 457 1.01E-153 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CO689_RS12950 49260975113fcd6c2be52c891ab2a588 145 TIGRFAM TIGR04191 YphP_YqiW: putative bacilliredoxin, YphP/YqiW family 8 142 1.4E-60 T 28-03-2018 IPR009474 Putative bacilliredoxin, YphP/YqiW family CO689_RS12950 49260975113fcd6c2be52c891ab2a588 145 Pfam PF06491 Disulphide isomerase 8 142 4.4E-60 T 28-03-2018 IPR009474 Putative bacilliredoxin, YphP/YqiW family CO689_RS02450 ec924a2c87a1804eba5e017d63b42db1 287 TIGRFAM TIGR01146 ATPsyn_F1gamma: ATP synthase F1, gamma subunit 1 286 3.5E-103 T 28-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CO689_RS02450 ec924a2c87a1804eba5e017d63b42db1 287 Hamap MF_00815 ATP synthase gamma chain [atpG]. 1 286 35.115 T 28-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CO689_RS02450 ec924a2c87a1804eba5e017d63b42db1 287 Gene3D G3DSA:1.10.287.80 238 281 4.6E-15 T 28-03-2018 CO689_RS02450 ec924a2c87a1804eba5e017d63b42db1 287 Gene3D G3DSA:1.10.287.80 2 41 1.3E-16 T 28-03-2018 CO689_RS02450 ec924a2c87a1804eba5e017d63b42db1 287 SUPERFAMILY SSF52943 3 286 4.84E-86 T 28-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CO689_RS02450 ec924a2c87a1804eba5e017d63b42db1 287 Pfam PF00231 ATP synthase 3 286 4.0E-95 T 28-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CO689_RS02450 ec924a2c87a1804eba5e017d63b42db1 287 Gene3D G3DSA:3.40.1380.10 42 237 3.9E-70 T 28-03-2018 CO689_RS02450 ec924a2c87a1804eba5e017d63b42db1 287 PRINTS PR00126 ATP synthase gamma subunit signature 264 285 6.8E-37 T 28-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CO689_RS02450 ec924a2c87a1804eba5e017d63b42db1 287 PRINTS PR00126 ATP synthase gamma subunit signature 165 182 6.8E-37 T 28-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CO689_RS02450 ec924a2c87a1804eba5e017d63b42db1 287 PRINTS PR00126 ATP synthase gamma subunit signature 233 252 6.8E-37 T 28-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CO689_RS02450 ec924a2c87a1804eba5e017d63b42db1 287 PRINTS PR00126 ATP synthase gamma subunit signature 72 91 6.8E-37 T 28-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CO689_RS03415 09433d154421ab69e97862a91d7b359d 204 Gene3D G3DSA:3.40.50.300 4 179 2.7E-16 T 28-03-2018 CO689_RS03415 09433d154421ab69e97862a91d7b359d 204 Hamap MF_01389 Urease accessory protein UreG [ureG]. 3 201 45.088 T 28-03-2018 IPR004400 Urease accessory protein UreG GO:0003924|GO:0006807|GO:0016151 CO689_RS03415 09433d154421ab69e97862a91d7b359d 204 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 7 176 9.3E-38 T 28-03-2018 IPR003495 CobW/HypB/UreG, nucleotide-binding domain CO689_RS03415 09433d154421ab69e97862a91d7b359d 204 SUPERFAMILY SSF52540 3 196 8.8E-34 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CO689_RS03415 09433d154421ab69e97862a91d7b359d 204 TIGRFAM TIGR00101 ureG: urease accessory protein UreG 5 201 6.2E-95 T 28-03-2018 IPR004400 Urease accessory protein UreG GO:0003924|GO:0006807|GO:0016151 CO689_RS03415 09433d154421ab69e97862a91d7b359d 204 PIRSF PIRSF005624 1 202 4.1E-47 T 28-03-2018 IPR012202 [NiFe]-hydrogenase/urease maturation factor, Ni2-binding GTPase GO:0003924|GO:0016151 CO689_RS12155 4e81c486ccb6ff790d39d312f1eabe9d 470 ProSitePatterns PS01035 PTS EIIB domains cysteine phosphorylation site signature. 19 36 - T 28-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 CO689_RS12155 4e81c486ccb6ff790d39d312f1eabe9d 470 SUPERFAMILY SSF55604 6 79 2.88E-21 T 28-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 CO689_RS12155 4e81c486ccb6ff790d39d312f1eabe9d 470 Gene3D G3DSA:3.30.1360.60 4 80 7.3E-28 T 28-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 CO689_RS12155 4e81c486ccb6ff790d39d312f1eabe9d 470 Pfam PF02378 Phosphotransferase system, EIIC 109 400 2.5E-40 T 28-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 CO689_RS12155 4e81c486ccb6ff790d39d312f1eabe9d 470 TIGRFAM TIGR00826 EIIB_glc: PTS system, glucose-like IIB component 29 108 1.0E-19 T 28-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 CO689_RS12155 4e81c486ccb6ff790d39d312f1eabe9d 470 TIGRFAM TIGR01996 PTS-II-BC-sucr: PTS system, sucrose-specific IIBC component 4 456 5.6E-184 T 28-03-2018 IPR010973 Phosphotransferase system, sucrose-specific IIBC component GO:0008982|GO:0009401|GO:0016021 CO689_RS12155 4e81c486ccb6ff790d39d312f1eabe9d 470 Pfam PF00367 phosphotransferase system, EIIB 9 41 4.5E-16 T 28-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 CO689_RS06590 7681a23a40035c55358c15f4e661fceb 79 SUPERFAMILY SSF158221 2 39 8.24E-12 T 28-03-2018 CO689_RS06590 7681a23a40035c55358c15f4e661fceb 79 Pfam PF05979 Bacterial protein of unknown function (DUF896) 3 64 3.1E-25 T 28-03-2018 IPR009242 Protein of unknown function DUF896 CO689_RS06590 7681a23a40035c55358c15f4e661fceb 79 Gene3D G3DSA:1.10.287.540 1 53 3.9E-20 T 28-03-2018 CO689_RS06590 7681a23a40035c55358c15f4e661fceb 79 Hamap MF_01103 UPF0291 protein . 1 57 12.797 T 28-03-2018 IPR009242 Protein of unknown function DUF896 CO689_RS00255 867a387204145e1e87c24ac75363516c 307 PRINTS PR00990 Ribokinase signature 173 188 3.5E-25 T 28-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 CO689_RS00255 867a387204145e1e87c24ac75363516c 307 PRINTS PR00990 Ribokinase signature 106 119 3.5E-25 T 28-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 CO689_RS00255 867a387204145e1e87c24ac75363516c 307 PRINTS PR00990 Ribokinase signature 217 228 3.5E-25 T 28-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 CO689_RS00255 867a387204145e1e87c24ac75363516c 307 PRINTS PR00990 Ribokinase signature 7 28 3.5E-25 T 28-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 CO689_RS00255 867a387204145e1e87c24ac75363516c 307 PRINTS PR00990 Ribokinase signature 34 53 3.5E-25 T 28-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 CO689_RS00255 867a387204145e1e87c24ac75363516c 307 SUPERFAMILY SSF53613 5 304 3.59E-80 T 28-03-2018 IPR029056 Ribokinase-like CO689_RS00255 867a387204145e1e87c24ac75363516c 307 ProSitePatterns PS00583 pfkB family of carbohydrate kinases signature 1. 39 63 - T 28-03-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 CO689_RS00255 867a387204145e1e87c24ac75363516c 307 Hamap MF_01987 Ribokinase [rbsK]. 3 301 22.505 T 28-03-2018 IPR011877 Ribokinase GO:0004747|GO:0006014 KEGG: 00030+2.7.1.15|Reactome: R-HSA-71336 CO689_RS00255 867a387204145e1e87c24ac75363516c 307 Gene3D G3DSA:3.40.1190.20 1 307 3.8E-79 T 28-03-2018 IPR029056 Ribokinase-like CO689_RS00255 867a387204145e1e87c24ac75363516c 307 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 246 259 - T 28-03-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 CO689_RS00255 867a387204145e1e87c24ac75363516c 307 TIGRFAM TIGR02152 D_ribokin_bact: ribokinase 5 299 2.7E-92 T 28-03-2018 IPR011877 Ribokinase GO:0004747|GO:0006014 KEGG: 00030+2.7.1.15|Reactome: R-HSA-71336 CO689_RS00255 867a387204145e1e87c24ac75363516c 307 Pfam PF00294 pfkB family carbohydrate kinase 4 294 3.1E-72 T 28-03-2018 IPR011611 Carbohydrate kinase PfkB CO689_RS00255 867a387204145e1e87c24ac75363516c 307 PIRSF PIRSF000535 10 306 7.9E-31 T 28-03-2018 IPR017583 Tagatose/fructose phosphokinase GO:0005975|GO:0016773 CO689_RS12725 c0392d660f4cb6123e98b425ecc02a71 323 Gene3D G3DSA:3.30.930.10 67 276 1.1E-59 T 28-03-2018 CO689_RS12725 c0392d660f4cb6123e98b425ecc02a71 323 Gene3D G3DSA:1.10.10.10 1 63 4.3E-8 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS12725 c0392d660f4cb6123e98b425ecc02a71 323 SUPERFAMILY SSF46785 6 60 9.62E-8 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS12725 c0392d660f4cb6123e98b425ecc02a71 323 Pfam PF08279 HTH domain 6 59 4.9E-12 T 28-03-2018 IPR013196 Helix-turn-helix, type 11 CO689_RS12725 c0392d660f4cb6123e98b425ecc02a71 323 SUPERFAMILY SSF50037 281 322 5.04E-5 T 28-03-2018 IPR008988 Transcriptional repressor, C-terminal CO689_RS12725 c0392d660f4cb6123e98b425ecc02a71 323 Pfam PF02237 Biotin protein ligase C terminal domain 283 323 5.4E-5 T 28-03-2018 IPR003142 Biotin protein ligase, C-terminal GO:0006464 KEGG: 00780+6.3.4.15|Reactome: R-HSA-196780 CO689_RS12725 c0392d660f4cb6123e98b425ecc02a71 323 Pfam PF03099 Biotin/lipoate A/B protein ligase family 105 212 6.6E-13 T 28-03-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 CO689_RS12725 c0392d660f4cb6123e98b425ecc02a71 323 Hamap MF_00978 Bifunctional ligase/repressor BirA [birA]. 7 323 29.93 T 28-03-2018 IPR030855 Bifunctional ligase/repressor BirA GO:0004077|GO:0006355 KEGG: 00780+6.3.4.15 CO689_RS12725 c0392d660f4cb6123e98b425ecc02a71 323 Gene3D G3DSA:2.30.30.100 278 321 3.5E-10 T 28-03-2018 CO689_RS12725 c0392d660f4cb6123e98b425ecc02a71 323 TIGRFAM TIGR00121 birA_ligase: biotin--[acetyl-CoA-carboxylase] ligase 85 321 1.4E-56 T 28-03-2018 IPR004408 Biotin--acetyl-CoA-carboxylase ligase GO:0004077|GO:0006464 KEGG: 00780+6.3.4.15|Reactome: R-HSA-196780 CO689_RS12725 c0392d660f4cb6123e98b425ecc02a71 323 SUPERFAMILY SSF55681 81 274 1.99E-54 T 28-03-2018 CO689_RS04360 307d3a068731420d858013d1520cccf8 296 TIGRFAM TIGR00718 sda_alpha: L-serine dehydratase, iron-sulfur-dependent, alpha subunit 1 291 2.9E-112 T 28-03-2018 IPR004642 Serine dehydratase, alpha subunit GO:0003941|GO:0006094 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17 CO689_RS04360 307d3a068731420d858013d1520cccf8 296 Pfam PF03313 Serine dehydratase alpha chain 14 276 1.2E-69 T 28-03-2018 IPR005130 Serine dehydratase-like, alpha subunit CO689_RS04360 307d3a068731420d858013d1520cccf8 296 Gene3D G3DSA:1.10.4100.10 22 264 2.4E-25 T 28-03-2018 CO689_RS04075 94a80d2dccea523bf407cf02d33d07cf 208 Pfam PF13529 Peptidase_C39 like family 5 157 8.5E-21 T 28-03-2018 CO689_RS04075 94a80d2dccea523bf407cf02d33d07cf 208 Gene3D G3DSA:3.90.70.10 18 208 8.7E-13 T 28-03-2018 CO689_RS04075 94a80d2dccea523bf407cf02d33d07cf 208 PIRSF PIRSF032442 1 201 3.9E-53 T 28-03-2018 IPR016997 Uncharacterised conserved protein UCP032442 CO689_RS11750 d6c248751c04e642fdf921c86c4b8390 249 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 7 240 7.4E-37 T 28-03-2018 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 CO689_RS11750 d6c248751c04e642fdf921c86c4b8390 249 SUPERFAMILY SSF51695 3 244 3.4E-58 T 28-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 CO689_RS11750 d6c248751c04e642fdf921c86c4b8390 249 Gene3D G3DSA:3.20.20.190 1 248 9.9E-57 T 28-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 CO689_RS08120 4e2a827a3cbd14d39b6504f9a6fc9cf0 359 Gene3D G3DSA:3.20.10.10 181 352 6.1E-55 T 28-03-2018 CO689_RS08120 4e2a827a3cbd14d39b6504f9a6fc9cf0 359 ProSitePatterns PS00770 Aminotransferases class-IV signature. 233 262 - T 28-03-2018 IPR018300 Aminotransferase, class IV, conserved site GO:0003824|GO:0008152 Reactome: R-HSA-70895 CO689_RS08120 4e2a827a3cbd14d39b6504f9a6fc9cf0 359 Gene3D G3DSA:3.30.470.10 1 180 2.9E-64 T 28-03-2018 CO689_RS08120 4e2a827a3cbd14d39b6504f9a6fc9cf0 359 TIGRFAM TIGR01123 ilvE_II: branched-chain amino acid aminotransferase 44 355 5.0E-123 T 28-03-2018 IPR005786 Branched-chain amino acid aminotransferase II GO:0004084|GO:0009081 KEGG: 00270+2.6.1.42|KEGG: 00280+2.6.1.42|KEGG: 00290+2.6.1.42|KEGG: 00770+2.6.1.42|KEGG: 00966+2.6.1.42|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5108|MetaCyc: PWY-7767|Reactome: R-HSA-70895 CO689_RS08120 4e2a827a3cbd14d39b6504f9a6fc9cf0 359 Pfam PF01063 Amino-transferase class IV 69 310 7.2E-40 T 28-03-2018 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 CO689_RS08120 4e2a827a3cbd14d39b6504f9a6fc9cf0 359 SUPERFAMILY SSF56752 12 353 1.01E-115 T 28-03-2018 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 CO689_RS08120 4e2a827a3cbd14d39b6504f9a6fc9cf0 359 PIRSF PIRSF006468 1 358 8.9E-130 T 28-03-2018 IPR005786 Branched-chain amino acid aminotransferase II GO:0004084|GO:0009081 KEGG: 00270+2.6.1.42|KEGG: 00280+2.6.1.42|KEGG: 00290+2.6.1.42|KEGG: 00770+2.6.1.42|KEGG: 00966+2.6.1.42|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5108|MetaCyc: PWY-7767|Reactome: R-HSA-70895 CO689_RS06040 ad12bfb1d4dff732f8806ced9c6fb1d2 356 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 32 143 6.9E-36 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CO689_RS06040 ad12bfb1d4dff732f8806ced9c6fb1d2 356 SUPERFAMILY SSF50129 9 180 2.13E-60 T 28-03-2018 IPR011032 GroES-like CO689_RS06040 ad12bfb1d4dff732f8806ced9c6fb1d2 356 Gene3D G3DSA:3.40.50.10730 167 312 2.4E-34 T 28-03-2018 CO689_RS06040 ad12bfb1d4dff732f8806ced9c6fb1d2 356 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 69 83 - T 28-03-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 CO689_RS06040 ad12bfb1d4dff732f8806ced9c6fb1d2 356 Pfam PF00107 Zinc-binding dehydrogenase 183 307 5.0E-32 T 28-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CO689_RS06040 ad12bfb1d4dff732f8806ced9c6fb1d2 356 SUPERFAMILY SSF51735 147 310 6.04E-45 T 28-03-2018 IPR016040 NAD(P)-binding domain CO689_RS06040 ad12bfb1d4dff732f8806ced9c6fb1d2 356 Gene3D G3DSA:3.90.180.10 9 166 2.1E-57 T 28-03-2018 CO689_RS06040 ad12bfb1d4dff732f8806ced9c6fb1d2 356 SMART SM00829 19 349 5.9E-4 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CO689_RS09740 7e0fc44e6649ae09126f5a6531557a8b 398 TIGRFAM TIGR01537 portal_HK97: phage portal protein, HK97 family 21 358 6.0E-98 T 28-03-2018 IPR006427 Phage portal protein, HK97 CO689_RS09740 7e0fc44e6649ae09126f5a6531557a8b 398 Pfam PF04860 Phage portal protein 26 351 4.1E-62 T 28-03-2018 IPR006944 Bacteriophage/Gene transfer agent portal protein CO689_RS13335 ddd578e87d9ad29d111b760d0efe3815 745 TIGRFAM TIGR00361 ComEC_Rec2: DNA internalization-related competence protein ComEC/Rec2 169 729 2.7E-74 T 28-03-2018 IPR004797 Competence protein ComEC/Rec2 GO:0016021|GO:0030420 CO689_RS13335 ddd578e87d9ad29d111b760d0efe3815 745 TIGRFAM TIGR00360 ComEC_N-term: ComEC/Rec2-related protein 213 380 5.6E-21 T 28-03-2018 IPR004477 ComEC/Rec2-related protein CO689_RS13335 ddd578e87d9ad29d111b760d0efe3815 745 SMART SM00849 486 700 4.2E-11 T 28-03-2018 IPR001279 Metallo-beta-lactamase CO689_RS13335 ddd578e87d9ad29d111b760d0efe3815 745 Pfam PF00753 Metallo-beta-lactamase superfamily 484 682 3.4E-13 T 28-03-2018 IPR001279 Metallo-beta-lactamase CO689_RS13335 ddd578e87d9ad29d111b760d0efe3815 745 SUPERFAMILY SSF56281 477 738 3.8E-44 T 28-03-2018 IPR001279 Metallo-beta-lactamase CO689_RS13335 ddd578e87d9ad29d111b760d0efe3815 745 Pfam PF03772 Competence protein 192 448 2.0E-39 T 28-03-2018 IPR004477 ComEC/Rec2-related protein CO689_RS13335 ddd578e87d9ad29d111b760d0efe3815 745 Gene3D G3DSA:3.60.15.10 469 744 3.6E-27 T 28-03-2018 IPR001279 Metallo-beta-lactamase CO689_RS07295 e55557fee8c590c3e626aff45706526d 568 TIGRFAM TIGR02041 CysI: sulfite reductase (NADPH) hemoprotein, beta-component 16 558 2.2E-252 T 28-03-2018 IPR011786 Sulphite reductase (NADPH) hemoprotein, beta subunit GO:0004783|GO:0008652|GO:0009337|GO:0050661|GO:0051539|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CO689_RS07295 e55557fee8c590c3e626aff45706526d 568 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 351 416 1.3E-16 T 28-03-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CO689_RS07295 e55557fee8c590c3e626aff45706526d 568 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 76 135 9.5E-17 T 28-03-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CO689_RS07295 e55557fee8c590c3e626aff45706526d 568 SUPERFAMILY SSF56014 145 343 1.23E-55 T 28-03-2018 CO689_RS07295 e55557fee8c590c3e626aff45706526d 568 Gene3D G3DSA:3.30.413.10 425 562 6.4E-29 T 28-03-2018 CO689_RS07295 e55557fee8c590c3e626aff45706526d 568 SUPERFAMILY SSF56014 426 557 7.98E-36 T 28-03-2018 CO689_RS07295 e55557fee8c590c3e626aff45706526d 568 PRINTS PR00397 Sirohaem Fe-binding site signature 429 447 1.0E-8 T 28-03-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CO689_RS07295 e55557fee8c590c3e626aff45706526d 568 PRINTS PR00397 Sirohaem Fe-binding site signature 477 495 1.0E-8 T 28-03-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CO689_RS07295 e55557fee8c590c3e626aff45706526d 568 ProSitePatterns PS00365 Nitrite and sulfite reductases iron-sulfur/siroheme-binding site. 477 493 - T 28-03-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CO689_RS07295 e55557fee8c590c3e626aff45706526d 568 Gene3D G3DSA:3.30.413.10 138 345 4.9E-53 T 28-03-2018 CO689_RS07295 e55557fee8c590c3e626aff45706526d 568 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 170 329 3.5E-47 T 28-03-2018 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CO689_RS07295 e55557fee8c590c3e626aff45706526d 568 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 428 557 4.6E-5 T 28-03-2018 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CO689_RS07295 e55557fee8c590c3e626aff45706526d 568 SUPERFAMILY SSF55124 346 420 5.4E-20 T 28-03-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CO689_RS07295 e55557fee8c590c3e626aff45706526d 568 Gene3D G3DSA:3.30.413.10 76 136 1.3E-4 T 28-03-2018 CO689_RS07295 e55557fee8c590c3e626aff45706526d 568 Hamap MF_01540 Sulfite reductase [NADPH] hemoprotein beta-component [cysI]. 7 568 55.283 T 28-03-2018 IPR011786 Sulphite reductase (NADPH) hemoprotein, beta subunit GO:0004783|GO:0008652|GO:0009337|GO:0050661|GO:0051539|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CO689_RS07295 e55557fee8c590c3e626aff45706526d 568 SUPERFAMILY SSF55124 12 144 3.49E-30 T 28-03-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CO689_RS08725 3b36cb671264041ef0c100522e5fda83 191 Pfam PF03641 Possible lysine decarboxylase 49 177 9.0E-37 T 28-03-2018 IPR031100 LOG family CO689_RS08725 3b36cb671264041ef0c100522e5fda83 191 TIGRFAM TIGR00730 TIGR00730: TIGR00730 family protein 5 182 2.7E-53 T 28-03-2018 IPR005269 Cytokinin riboside 5'-monophosphate phosphoribohydrolase LOG CO689_RS08725 3b36cb671264041ef0c100522e5fda83 191 Gene3D G3DSA:3.40.50.450 1 181 1.8E-51 T 28-03-2018 CO689_RS08725 3b36cb671264041ef0c100522e5fda83 191 SUPERFAMILY SSF102405 3 182 9.31E-55 T 28-03-2018 CO689_RS07475 89c8e0868b1be3086db8d612e6cadc6a 490 Gene3D G3DSA:1.10.1060.10 4 153 3.5E-40 T 28-03-2018 CO689_RS07475 89c8e0868b1be3086db8d612e6cadc6a 490 TIGRFAM TIGR01317 GOGAT_sm_gam: glutamate synthase, NADH/NADPH, small subunit 5 488 1.8E-184 T 28-03-2018 IPR006005 Glutamate synthase, NADH/NADPH, small subunit 1 GO:0006537|GO:0016639|GO:0055114 CO689_RS07475 89c8e0868b1be3086db8d612e6cadc6a 490 Gene3D G3DSA:3.50.50.60 375 490 4.1E-15 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CO689_RS07475 89c8e0868b1be3086db8d612e6cadc6a 490 Gene3D G3DSA:3.50.50.60 250 337 9.6E-20 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CO689_RS07475 89c8e0868b1be3086db8d612e6cadc6a 490 SUPERFAMILY SSF51971 152 418 7.06E-56 T 28-03-2018 CO689_RS07475 89c8e0868b1be3086db8d612e6cadc6a 490 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 154 314 6.0E-18 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CO689_RS07475 89c8e0868b1be3086db8d612e6cadc6a 490 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 405 472 9.8E-8 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CO689_RS07475 89c8e0868b1be3086db8d612e6cadc6a 490 PRINTS PR00419 Adrenodoxin reductase family signature 219 229 2.8E-22 T 28-03-2018 CO689_RS07475 89c8e0868b1be3086db8d612e6cadc6a 490 PRINTS PR00419 Adrenodoxin reductase family signature 154 176 2.8E-22 T 28-03-2018 CO689_RS07475 89c8e0868b1be3086db8d612e6cadc6a 490 PRINTS PR00419 Adrenodoxin reductase family signature 295 309 2.8E-22 T 28-03-2018 CO689_RS07475 89c8e0868b1be3086db8d612e6cadc6a 490 PRINTS PR00419 Adrenodoxin reductase family signature 177 190 2.8E-22 T 28-03-2018 CO689_RS07475 89c8e0868b1be3086db8d612e6cadc6a 490 SUPERFAMILY SSF46548 4 163 4.39E-33 T 28-03-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 CO689_RS07475 89c8e0868b1be3086db8d612e6cadc6a 490 Pfam PF14691 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster 26 140 5.4E-24 T 28-03-2018 IPR028261 Dihydroprymidine dehydrogenase domain II Reactome: R-HSA-73621 CO689_RS07475 89c8e0868b1be3086db8d612e6cadc6a 490 Gene3D G3DSA:3.40.50.720 154 249 8.9E-21 T 28-03-2018 CO689_RS07475 89c8e0868b1be3086db8d612e6cadc6a 490 SUPERFAMILY SSF51971 392 488 2.71E-10 T 28-03-2018 CO689_RS07090 607dd09955fe67c4c428a0b2a2e9cde1 270 TIGRFAM TIGR00180 parB_part: ParB/RepB/Spo0J family partition protein 11 187 2.2E-60 T 28-03-2018 IPR004437 ParB/RepB/Spo0J partition protein family GO:0003677 CO689_RS07090 607dd09955fe67c4c428a0b2a2e9cde1 270 Gene3D G3DSA:1.10.10.730 103 150 6.5E-21 T 28-03-2018 CO689_RS07090 607dd09955fe67c4c428a0b2a2e9cde1 270 Pfam PF02195 ParB-like nuclease domain 14 101 7.0E-28 T 28-03-2018 IPR003115 ParB/Sulfiredoxin CO689_RS07090 607dd09955fe67c4c428a0b2a2e9cde1 270 SMART SM00470 13 102 1.2E-36 T 28-03-2018 IPR003115 ParB/Sulfiredoxin CO689_RS07090 607dd09955fe67c4c428a0b2a2e9cde1 270 Gene3D G3DSA:3.90.1530.10 1 102 3.2E-37 T 28-03-2018 CO689_RS07090 607dd09955fe67c4c428a0b2a2e9cde1 270 SUPERFAMILY SSF110849 13 104 5.23E-29 T 28-03-2018 IPR003115 ParB/Sulfiredoxin CO689_RS07090 607dd09955fe67c4c428a0b2a2e9cde1 270 SUPERFAMILY SSF109709 94 204 8.11E-34 T 28-03-2018 CO689_RS13775 fff91fe1781c75cbf7834560fa64e885 306 Pfam PF01695 IstB-like ATP binding protein 158 265 1.1E-7 T 28-03-2018 IPR002611 IstB-like ATP-binding protein GO:0005524 CO689_RS13775 fff91fe1781c75cbf7834560fa64e885 306 Gene3D G3DSA:3.40.50.300 104 298 3.8E-15 T 28-03-2018 CO689_RS13775 fff91fe1781c75cbf7834560fa64e885 306 SUPERFAMILY SSF52540 143 270 9.99E-16 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CO689_RS13775 fff91fe1781c75cbf7834560fa64e885 306 Pfam PF07319 Primosomal protein DnaI N-terminus 1 94 3.7E-27 T 28-03-2018 IPR009928 Primosomal DnaI, N-terminal CO689_RS03930 e052a750bb05313ffabdb03d2569a241 388 Gene3D G3DSA:1.20.1250.20 193 388 9.4E-28 T 28-03-2018 CO689_RS03930 e052a750bb05313ffabdb03d2569a241 388 Pfam PF07690 Major Facilitator Superfamily 16 342 1.5E-43 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CO689_RS03930 e052a750bb05313ffabdb03d2569a241 388 Gene3D G3DSA:1.20.1250.20 8 190 6.2E-23 T 28-03-2018 CO689_RS03930 e052a750bb05313ffabdb03d2569a241 388 SUPERFAMILY SSF103473 10 384 3.01E-61 T 28-03-2018 IPR020846 Major facilitator superfamily domain CO689_RS03030 083ee2da722a4618d880d733c4886617 121 Gene3D G3DSA:4.10.910.10 67 85 4.5E-17 T 28-03-2018 IPR027437 30s ribosomal protein S13, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CO689_RS03030 083ee2da722a4618d880d733c4886617 121 PIRSF PIRSF002134 1 121 9.4E-45 T 28-03-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CO689_RS03030 083ee2da722a4618d880d733c4886617 121 Hamap MF_01315 30S ribosomal protein S13 [rpsM]. 1 119 28.63 T 28-03-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CO689_RS03030 083ee2da722a4618d880d733c4886617 121 Gene3D G3DSA:4.10.910.10 86 121 3.0E-26 T 28-03-2018 IPR027437 30s ribosomal protein S13, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CO689_RS03030 083ee2da722a4618d880d733c4886617 121 SUPERFAMILY SSF46946 2 120 2.75E-45 T 28-03-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 CO689_RS03030 083ee2da722a4618d880d733c4886617 121 ProSitePatterns PS00646 Ribosomal protein S13 signature. 87 100 - T 28-03-2018 IPR018269 Ribosomal protein S13, conserved site GO:0003723|GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CO689_RS03030 083ee2da722a4618d880d733c4886617 121 TIGRFAM TIGR03631 uS13_bact: ribosomal protein uS13 3 114 3.5E-52 T 28-03-2018 IPR019980 Ribosomal protein S13, bacterial-type GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 CO689_RS03030 083ee2da722a4618d880d733c4886617 121 Gene3D G3DSA:1.10.8.50 1 66 6.7E-27 T 28-03-2018 CO689_RS03030 083ee2da722a4618d880d733c4886617 121 Pfam PF00416 Ribosomal protein S13/S18 3 108 1.8E-33 T 28-03-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CO689_RS12375 efe7a5d5b2b8ced2b886e4f67b78b67e 231 SUPERFAMILY SSF52540 2 228 4.51E-53 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CO689_RS12375 efe7a5d5b2b8ced2b886e4f67b78b67e 231 SMART SM00382 26 202 4.8E-16 T 28-03-2018 IPR003593 AAA+ ATPase domain CO689_RS12375 efe7a5d5b2b8ced2b886e4f67b78b67e 231 Pfam PF00005 ABC transporter 17 153 6.5E-24 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CO689_RS12375 efe7a5d5b2b8ced2b886e4f67b78b67e 231 ProSitePatterns PS00211 ABC transporters family signature. 125 139 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CO689_RS12375 efe7a5d5b2b8ced2b886e4f67b78b67e 231 Gene3D G3DSA:3.40.50.300 1 231 1.6E-56 T 28-03-2018 CO689_RS09130 4ee8340e2660e731f802bf92d6b5739a 660 SMART SM00490 460 546 3.9E-19 T 28-03-2018 IPR001650 Helicase, C-terminal CO689_RS09130 4ee8340e2660e731f802bf92d6b5739a 660 TIGRFAM TIGR00631 uvrb: excinuclease ABC subunit B 6 657 0.0 T 28-03-2018 IPR004807 UvrABC system, subunit B GO:0003677|GO:0005524|GO:0006281|GO:0006289|GO:0009381|GO:0009432 CO689_RS09130 4ee8340e2660e731f802bf92d6b5739a 660 Pfam PF12344 Ultra-violet resistance protein B 552 593 2.7E-25 T 28-03-2018 IPR024759 UvrB, YAD/RRR-motif-containing domain CO689_RS09130 4ee8340e2660e731f802bf92d6b5739a 660 Pfam PF04851 Type III restriction enzyme, res subunit 13 106 2.9E-12 T 28-03-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 CO689_RS09130 4ee8340e2660e731f802bf92d6b5739a 660 Gene3D G3DSA:3.40.50.300 416 589 3.8E-33 T 28-03-2018 CO689_RS09130 4ee8340e2660e731f802bf92d6b5739a 660 Pfam PF02151 UvrB/uvrC motif 624 658 5.1E-9 T 28-03-2018 IPR001943 UVR domain GO:0005515 CO689_RS09130 4ee8340e2660e731f802bf92d6b5739a 660 Hamap MF_00204 UvrABC system protein B [uvrB]. 4 659 44.227 T 28-03-2018 IPR004807 UvrABC system, subunit B GO:0003677|GO:0005524|GO:0006281|GO:0006289|GO:0009381|GO:0009432 CO689_RS09130 4ee8340e2660e731f802bf92d6b5739a 660 Pfam PF00271 Helicase conserved C-terminal domain 435 545 5.1E-19 T 28-03-2018 IPR001650 Helicase, C-terminal CO689_RS09130 4ee8340e2660e731f802bf92d6b5739a 660 SMART SM00487 10 426 4.9E-27 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CO689_RS09130 4ee8340e2660e731f802bf92d6b5739a 660 SUPERFAMILY SSF46600 617 658 3.79E-10 T 28-03-2018 IPR001943 UVR domain GO:0005515 CO689_RS09130 4ee8340e2660e731f802bf92d6b5739a 660 SUPERFAMILY SSF52540 470 594 6.75E-39 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CO689_RS09130 4ee8340e2660e731f802bf92d6b5739a 660 SUPERFAMILY SSF52540 33 81 6.75E-39 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CO689_RS09130 4ee8340e2660e731f802bf92d6b5739a 660 Gene3D G3DSA:4.10.860.10 600 660 5.1E-14 T 28-03-2018 IPR001943 UVR domain GO:0005515 CO689_RS09130 4ee8340e2660e731f802bf92d6b5739a 660 Gene3D G3DSA:3.40.50.300 11 415 4.6E-32 T 28-03-2018 CO689_RS09130 4ee8340e2660e731f802bf92d6b5739a 660 SUPERFAMILY SSF52540 5 415 4.59E-142 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CO689_RS01785 03cd8c11d847db78a8dfb4fb54ccfab6 475 SUPERFAMILY SSF89095 294 399 2.35E-35 T 28-03-2018 IPR003789 Aspartyl/glutamyl-tRNA amidotransferase subunit B-related GO:0016884 CO689_RS01785 03cd8c11d847db78a8dfb4fb54ccfab6 475 TIGRFAM TIGR00133 gatB: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit 1 472 4.2E-181 T 28-03-2018 IPR004413 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit GO:0016884 CO689_RS01785 03cd8c11d847db78a8dfb4fb54ccfab6 475 Hamap MF_00121 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B [gatB]. 2 473 38.943 T 28-03-2018 IPR004413 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit GO:0016884 CO689_RS01785 03cd8c11d847db78a8dfb4fb54ccfab6 475 Pfam PF02637 GatB domain 325 472 1.9E-54 T 28-03-2018 IPR018027 Asn/Gln amidotransferase GO:0016884 CO689_RS01785 03cd8c11d847db78a8dfb4fb54ccfab6 475 Gene3D G3DSA:1.10.10.410 412 473 2.5E-21 T 28-03-2018 IPR023168 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, C-terminal CO689_RS01785 03cd8c11d847db78a8dfb4fb54ccfab6 475 SMART SM00845 325 472 1.4E-75 T 28-03-2018 IPR018027 Asn/Gln amidotransferase GO:0016884 CO689_RS01785 03cd8c11d847db78a8dfb4fb54ccfab6 475 Pfam PF02934 GatB/GatE catalytic domain 5 285 2.3E-112 T 28-03-2018 IPR006075 Aspartyl/Glutamyl-tRNA(Gln) amidotransferase, subunit B/E, catalytic GO:0016874 CO689_RS01785 03cd8c11d847db78a8dfb4fb54ccfab6 475 ProSitePatterns PS01234 Glutamyl-tRNA(Gln) amidotransferase subunit B signature. 141 155 - T 28-03-2018 IPR017958 Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site GO:0016884 CO689_RS01785 03cd8c11d847db78a8dfb4fb54ccfab6 475 SUPERFAMILY SSF55931 4 293 2.03E-123 T 28-03-2018 CO689_RS07215 1848106b5e2f73ef13c55655bfa29b92 463 PRINTS PR00173 Glutamate-aspartate symporter signature 233 252 3.7E-19 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CO689_RS07215 1848106b5e2f73ef13c55655bfa29b92 463 PRINTS PR00173 Glutamate-aspartate symporter signature 106 131 3.7E-19 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CO689_RS07215 1848106b5e2f73ef13c55655bfa29b92 463 PRINTS PR00173 Glutamate-aspartate symporter signature 396 416 3.7E-19 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CO689_RS07215 1848106b5e2f73ef13c55655bfa29b92 463 PRINTS PR00173 Glutamate-aspartate symporter signature 76 96 3.7E-19 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CO689_RS07215 1848106b5e2f73ef13c55655bfa29b92 463 PRINTS PR00173 Glutamate-aspartate symporter signature 369 388 3.7E-19 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CO689_RS07215 1848106b5e2f73ef13c55655bfa29b92 463 SUPERFAMILY SSF118215 30 437 4.58E-87 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CO689_RS07215 1848106b5e2f73ef13c55655bfa29b92 463 Pfam PF00375 Sodium:dicarboxylate symporter family 32 441 2.3E-97 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CO689_RS07215 1848106b5e2f73ef13c55655bfa29b92 463 Gene3D G3DSA:1.10.3860.10 19 449 2.0E-86 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CO689_RS12075 ad9772c14ca60d1258fd54b3ccf346c3 154 Gene3D G3DSA:3.40.50.1360 14 136 3.4E-10 T 28-03-2018 CO689_RS12075 ad9772c14ca60d1258fd54b3ccf346c3 154 SMART SM01134 12 146 0.001 T 28-03-2018 CO689_RS12075 ad9772c14ca60d1258fd54b3ccf346c3 154 Pfam PF00455 DeoR C terminal sensor domain 17 135 1.9E-14 T 28-03-2018 IPR014036 DeoR C-terminal sensor domain CO689_RS12075 ad9772c14ca60d1258fd54b3ccf346c3 154 SUPERFAMILY SSF100950 17 135 1.47E-6 T 28-03-2018 CO689_RS07105 f6e82af21347209a05ad57365afca51a 365 Gene3D G3DSA:1.10.150.300 110 200 1.9E-30 T 28-03-2018 IPR023192 TGS-like domain Reactome: R-HSA-114608 CO689_RS07105 f6e82af21347209a05ad57365afca51a 365 SUPERFAMILY SSF81271 281 362 2.4E-37 T 28-03-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 CO689_RS07105 f6e82af21347209a05ad57365afca51a 365 SUPERFAMILY SSF52540 3 303 6.84E-91 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CO689_RS07105 f6e82af21347209a05ad57365afca51a 365 PIRSF PIRSF006641 1 365 1.8E-164 T 28-03-2018 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Reactome: R-HSA-114608 CO689_RS07105 f6e82af21347209a05ad57365afca51a 365 Gene3D G3DSA:3.10.20.30 265 364 1.6E-46 T 28-03-2018 IPR012675 Beta-grasp domain CO689_RS07105 f6e82af21347209a05ad57365afca51a 365 Hamap MF_00944 Ribosome-binding ATPase YchF [ychF]. 2 365 46.069 T 28-03-2018 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Reactome: R-HSA-114608 CO689_RS07105 f6e82af21347209a05ad57365afca51a 365 Gene3D G3DSA:3.40.50.300 1 80 2.8E-7 T 28-03-2018 CO689_RS07105 f6e82af21347209a05ad57365afca51a 365 Pfam PF06071 Protein of unknown function (DUF933) 281 364 1.2E-40 T 28-03-2018 IPR013029 Domain of unknown function DUF933 Reactome: R-HSA-114608 CO689_RS07105 f6e82af21347209a05ad57365afca51a 365 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 70 85 1.2E-34 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CO689_RS07105 f6e82af21347209a05ad57365afca51a 365 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 26 44 1.2E-34 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CO689_RS07105 f6e82af21347209a05ad57365afca51a 365 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 87 105 1.2E-34 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CO689_RS07105 f6e82af21347209a05ad57365afca51a 365 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 5 25 1.2E-34 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CO689_RS07105 f6e82af21347209a05ad57365afca51a 365 Pfam PF01926 50S ribosome-binding GTPase 5 116 5.9E-23 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CO689_RS07105 f6e82af21347209a05ad57365afca51a 365 TIGRFAM TIGR00092 TIGR00092: GTP-binding protein YchF 1 365 1.0E-161 T 28-03-2018 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Reactome: R-HSA-114608 CO689_RS10310 4c3ed177f9feeb6b6a1962765dc3d3dd 169 SUPERFAMILY SSF55144 1 168 3.14E-28 T 28-03-2018 IPR009097 Cyclic phosphodiesterase CO689_RS10310 4c3ed177f9feeb6b6a1962765dc3d3dd 169 Hamap MF_01444 Putative phosphoesterase . 1 169 34.857 T 28-03-2018 IPR022932 Putative phosphoesterase YjcG CO689_RS10310 4c3ed177f9feeb6b6a1962765dc3d3dd 169 Gene3D G3DSA:3.90.1140.10 1 169 3.0E-23 T 28-03-2018 CO689_RS10310 4c3ed177f9feeb6b6a1962765dc3d3dd 169 Pfam PF13563 2'-5' RNA ligase superfamily 12 155 1.9E-21 T 28-03-2018 CO689_RS09500 d61b5cddff6909e6ccca1a32f3d7c4f3 252 SMART SM00382 29 224 6.2E-5 T 28-03-2018 IPR003593 AAA+ ATPase domain CO689_RS09500 d61b5cddff6909e6ccca1a32f3d7c4f3 252 Gene3D G3DSA:3.40.50.300 2 252 2.1E-42 T 28-03-2018 CO689_RS09500 d61b5cddff6909e6ccca1a32f3d7c4f3 252 Pfam PF00005 ABC transporter 20 172 3.0E-20 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CO689_RS09500 d61b5cddff6909e6ccca1a32f3d7c4f3 252 ProSitePatterns PS00211 ABC transporters family signature. 147 161 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CO689_RS09500 d61b5cddff6909e6ccca1a32f3d7c4f3 252 SUPERFAMILY SSF52540 4 232 3.68E-43 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CO689_RS09500 d61b5cddff6909e6ccca1a32f3d7c4f3 252 TIGRFAM TIGR01978 sufC: FeS assembly ATPase SufC 5 245 9.2E-112 T 28-03-2018 IPR010230 FeS cluster assembly SUF system, ATPase SufC GO:0005524|GO:0006810 CO689_RS11710 f98c66f9f7ae4ab9660b5b54aeed7f0f 566 Gene3D G3DSA:3.30.930.10 11 456 6.0E-96 T 28-03-2018 CO689_RS11710 f98c66f9f7ae4ab9660b5b54aeed7f0f 566 SUPERFAMILY SSF55681 9 237 1.03E-99 T 28-03-2018 CO689_RS11710 f98c66f9f7ae4ab9660b5b54aeed7f0f 566 SUPERFAMILY SSF55681 403 473 1.03E-99 T 28-03-2018 CO689_RS11710 f98c66f9f7ae4ab9660b5b54aeed7f0f 566 Pfam PF04073 Aminoacyl-tRNA editing domain 257 373 3.2E-28 T 28-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 CO689_RS11710 f98c66f9f7ae4ab9660b5b54aeed7f0f 566 Gene3D G3DSA:3.40.50.800 457 566 2.9E-30 T 28-03-2018 IPR004154 Anticodon-binding CO689_RS11710 f98c66f9f7ae4ab9660b5b54aeed7f0f 566 SUPERFAMILY SSF52954 459 565 5.56E-29 T 28-03-2018 IPR004154 Anticodon-binding CO689_RS11710 f98c66f9f7ae4ab9660b5b54aeed7f0f 566 Pfam PF03129 Anticodon binding domain 472 561 9.1E-19 T 28-03-2018 IPR004154 Anticodon-binding CO689_RS11710 f98c66f9f7ae4ab9660b5b54aeed7f0f 566 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 95 455 8.0E-54 T 28-03-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 CO689_RS11710 f98c66f9f7ae4ab9660b5b54aeed7f0f 566 SUPERFAMILY SSF55826 218 385 1.18E-34 T 28-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 CO689_RS11710 f98c66f9f7ae4ab9660b5b54aeed7f0f 566 PRINTS PR01046 Prolyl-tRNA synthetase signature 144 155 2.0E-20 T 28-03-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 CO689_RS11710 f98c66f9f7ae4ab9660b5b54aeed7f0f 566 PRINTS PR01046 Prolyl-tRNA synthetase signature 68 86 2.0E-20 T 28-03-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 CO689_RS11710 f98c66f9f7ae4ab9660b5b54aeed7f0f 566 PRINTS PR01046 Prolyl-tRNA synthetase signature 104 115 2.0E-20 T 28-03-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 CO689_RS11710 f98c66f9f7ae4ab9660b5b54aeed7f0f 566 PRINTS PR01046 Prolyl-tRNA synthetase signature 134 142 2.0E-20 T 28-03-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 CO689_RS11710 f98c66f9f7ae4ab9660b5b54aeed7f0f 566 Hamap MF_01569 Proline--tRNA ligase [proS]. 1 564 40.457 T 28-03-2018 IPR023717 Prolyl-tRNA synthetase, class IIa, type 1 GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 CO689_RS11710 f98c66f9f7ae4ab9660b5b54aeed7f0f 566 TIGRFAM TIGR00409 proS_fam_II: proline--tRNA ligase 1 560 4.5E-228 T 28-03-2018 IPR004500 Prolyl-tRNA synthetase, class IIa, bacterial-type GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 CO689_RS12010 9998a6faa10e49d669c1565a6cb52922 157 Gene3D G3DSA:3.40.30.10 1 157 5.2E-50 T 28-03-2018 CO689_RS12010 9998a6faa10e49d669c1565a6cb52922 157 ProSitePatterns PS00763 Glutathione peroxidases signature 2. 59 66 - T 28-03-2018 IPR029760 Glutathione peroxidase conserved site Reactome: R-HSA-3299685 CO689_RS12010 9998a6faa10e49d669c1565a6cb52922 157 SUPERFAMILY SSF52833 1 157 3.04E-63 T 28-03-2018 IPR012336 Thioredoxin-like fold CO689_RS12010 9998a6faa10e49d669c1565a6cb52922 157 Pfam PF00255 Glutathione peroxidase 3 109 4.1E-42 T 28-03-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 CO689_RS12010 9998a6faa10e49d669c1565a6cb52922 157 PRINTS PR01011 Glutathione peroxidase family signature 56 72 1.1E-21 T 28-03-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 CO689_RS12010 9998a6faa10e49d669c1565a6cb52922 157 PRINTS PR01011 Glutathione peroxidase family signature 121 130 1.1E-21 T 28-03-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 CO689_RS12010 9998a6faa10e49d669c1565a6cb52922 157 PRINTS PR01011 Glutathione peroxidase family signature 21 38 1.1E-21 T 28-03-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 CO689_RS12010 9998a6faa10e49d669c1565a6cb52922 157 ProSitePatterns PS00460 Glutathione peroxidases active site. 23 38 - T 28-03-2018 IPR029759 Glutathione peroxidase active site Reactome: R-HSA-3299685 CO689_RS12010 9998a6faa10e49d669c1565a6cb52922 157 PIRSF PIRSF000303 1 157 2.9E-70 T 28-03-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 CO689_RS13200 fae5d17579076b662806cdafdedd5200 223 Pfam PF04816 tRNA (adenine(22)-N(1))-methyltransferase 19 220 2.7E-71 T 28-03-2018 IPR006901 tRNA methyltransferase TrmK GO:0016429 CO689_RS13200 fae5d17579076b662806cdafdedd5200 223 Gene3D G3DSA:3.40.50.150 2 163 3.8E-12 T 28-03-2018 CO689_RS13200 fae5d17579076b662806cdafdedd5200 223 SUPERFAMILY SSF53335 10 145 4.56E-7 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CO689_RS13200 fae5d17579076b662806cdafdedd5200 223 PIRSF PIRSF018637 1 223 1.3E-76 T 28-03-2018 IPR006901 tRNA methyltransferase TrmK GO:0016429 CO689_RS13290 17ec5e5d3cd1714d93cf6bd8530386e8 312 Gene3D G3DSA:3.40.50.150 114 312 5.9E-41 T 28-03-2018 CO689_RS13290 17ec5e5d3cd1714d93cf6bd8530386e8 312 Pfam PF06325 Ribosomal protein L11 methyltransferase (PrmA) 2 309 2.6E-104 T 28-03-2018 CO689_RS13290 17ec5e5d3cd1714d93cf6bd8530386e8 312 TIGRFAM TIGR00406 prmA: ribosomal protein L11 methyltransferase 3 303 3.8E-80 T 28-03-2018 IPR004498 Ribosomal protein L11 methyltransferase GO:0006479|GO:0008276 CO689_RS13290 17ec5e5d3cd1714d93cf6bd8530386e8 312 PIRSF PIRSF000401 1 311 1.1E-112 T 28-03-2018 IPR004498 Ribosomal protein L11 methyltransferase GO:0006479|GO:0008276 CO689_RS13290 17ec5e5d3cd1714d93cf6bd8530386e8 312 Hamap MF_00735 Ribosomal protein L11 methyltransferase [prmA]. 3 309 34.559 T 28-03-2018 IPR004498 Ribosomal protein L11 methyltransferase GO:0006479|GO:0008276 CO689_RS13290 17ec5e5d3cd1714d93cf6bd8530386e8 312 SUPERFAMILY SSF53335 66 307 3.7E-44 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CO689_RS10455 d0b0b2da713ebb694f8de06c1aec897b 237 Gene3D G3DSA:2.40.260.10 49 234 2.4E-61 T 28-03-2018 IPR023365 Sortase domain CO689_RS10455 d0b0b2da713ebb694f8de06c1aec897b 237 TIGRFAM TIGR03064 sortase_srtB: sortase, SrtB family 5 229 2.4E-73 T 28-03-2018 IPR009835 Sortase B family CO689_RS10455 d0b0b2da713ebb694f8de06c1aec897b 237 SUPERFAMILY SSF63817 13 235 9.94E-66 T 28-03-2018 IPR023365 Sortase domain CO689_RS10455 d0b0b2da713ebb694f8de06c1aec897b 237 Pfam PF04203 Sortase family 68 233 5.6E-23 T 28-03-2018 IPR005754 Sortase family CO689_RS08755 4505d57ac734bb09933869ffb5e5ec59 146 SUPERFAMILY SSF46785 6 139 1.97E-31 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS08755 4505d57ac734bb09933869ffb5e5ec59 146 Pfam PF01047 MarR family 36 94 1.0E-14 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CO689_RS08755 4505d57ac734bb09933869ffb5e5ec59 146 ProSitePatterns PS01117 MarR-type HTH domain signature. 68 102 - T 28-03-2018 IPR023187 Transcriptional regulator MarR-type, conserved site CO689_RS08755 4505d57ac734bb09933869ffb5e5ec59 146 SMART SM00347 29 127 5.6E-19 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CO689_RS08755 4505d57ac734bb09933869ffb5e5ec59 146 Gene3D G3DSA:1.10.10.10 7 146 9.3E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS05780 53feb3fa0e75f9f90f75d05e7d81c1d8 514 TIGRFAM TIGR02121 Na_Pro_sym: sodium/proline symporter 17 509 7.0E-218 T 28-03-2018 IPR011851 Sodium/proline symporter GO:0005298|GO:0006814|GO:0015824|GO:0016021|GO:0031402 CO689_RS05780 53feb3fa0e75f9f90f75d05e7d81c1d8 514 Pfam PF00474 Sodium:solute symporter family 47 447 3.2E-100 T 28-03-2018 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 CO689_RS05780 53feb3fa0e75f9f90f75d05e7d81c1d8 514 TIGRFAM TIGR00813 sss: transporter, solute:sodium symporter (SSS) family 47 447 9.2E-91 T 28-03-2018 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 CO689_RS12490 a68d0fa686359db7b21ece78fa872c9f 66 SMART SM00357 3 66 8.6E-31 T 28-03-2018 IPR011129 Cold shock domain GO:0003676 CO689_RS12490 a68d0fa686359db7b21ece78fa872c9f 66 SUPERFAMILY SSF50249 1 65 5.61E-25 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CO689_RS12490 a68d0fa686359db7b21ece78fa872c9f 66 ProSitePatterns PS00352 'Cold-shock' domain signature. 15 33 - T 28-03-2018 IPR019844 Cold-shock conserved site CO689_RS12490 a68d0fa686359db7b21ece78fa872c9f 66 PIRSF PIRSF002599 1 66 9.4E-26 T 28-03-2018 IPR012156 Cold shock, CspA GO:0003676 CO689_RS12490 a68d0fa686359db7b21ece78fa872c9f 66 Pfam PF00313 'Cold-shock' DNA-binding domain 3 65 1.1E-30 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CO689_RS12490 a68d0fa686359db7b21ece78fa872c9f 66 PRINTS PR00050 Cold shock protein signature 4 19 4.2E-20 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CO689_RS12490 a68d0fa686359db7b21ece78fa872c9f 66 PRINTS PR00050 Cold shock protein signature 39 57 4.2E-20 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CO689_RS12490 a68d0fa686359db7b21ece78fa872c9f 66 PRINTS PR00050 Cold shock protein signature 24 33 4.2E-20 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CO689_RS12490 a68d0fa686359db7b21ece78fa872c9f 66 Gene3D G3DSA:2.40.50.140 1 66 9.3E-28 T 28-03-2018 CO689_RS12755 243557d71aa0260dad1deb7079d14457 185 PIRSF PIRSF007165 2 179 4.7E-31 T 28-03-2018 IPR011188 Uncharacterised protein family UPF0302 CO689_RS12755 243557d71aa0260dad1deb7079d14457 185 Pfam PF08864 UPF0302 domain 10 106 2.1E-20 T 28-03-2018 IPR014963 Uncharacterised domain UPF0302, N-terminal CO689_RS01910 8dbfda9f575d3a5b98e4e47e02892d5a 347 Gene3D G3DSA:3.60.60.10 98 341 1.5E-26 T 28-03-2018 CO689_RS01910 8dbfda9f575d3a5b98e4e47e02892d5a 347 SUPERFAMILY SSF56235 105 331 3.78E-9 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CO689_RS01910 8dbfda9f575d3a5b98e4e47e02892d5a 347 Pfam PF03417 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase 107 313 1.1E-66 T 28-03-2018 IPR005079 Peptidase C45 CO689_RS08220 50c2c376c18771c630ca8f5664908c66 316 SUPERFAMILY SSF53850 44 310 1.83E-48 T 28-03-2018 CO689_RS08220 50c2c376c18771c630ca8f5664908c66 316 TIGRFAM TIGR01098 3A0109s03R: phosphate/phosphite/phosphonate ABC transporter, periplasmic binding protein 8 275 1.6E-74 T 28-03-2018 IPR005770 Phosphate/phosphite/phosphonate ABC transporter, periplasmic binding protein GO:0043190|GO:0055085 CO689_RS08220 50c2c376c18771c630ca8f5664908c66 316 Pfam PF12974 ABC transporter, phosphonate, periplasmic substrate-binding protein 52 301 1.3E-66 T 28-03-2018 CO689_RS08220 50c2c376c18771c630ca8f5664908c66 316 Gene3D G3DSA:3.40.190.10 43 145 9.2E-11 T 28-03-2018 CO689_RS08220 50c2c376c18771c630ca8f5664908c66 316 Gene3D G3DSA:3.40.190.10 150 298 1.0E-34 T 28-03-2018 CO689_RS08220 50c2c376c18771c630ca8f5664908c66 316 SMART SM00062 47 293 0.0027 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CO689_RS10590 602a6a893a88eccf2ccb640132355772 550 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 484 530 9.2E-7 T 28-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CO689_RS10590 602a6a893a88eccf2ccb640132355772 550 Gene3D G3DSA:3.30.310.50 451 548 1.9E-18 T 28-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CO689_RS10590 602a6a893a88eccf2ccb640132355772 550 Gene3D G3DSA:3.40.120.10 7 202 1.3E-47 T 28-03-2018 CO689_RS10590 602a6a893a88eccf2ccb640132355772 550 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 35 170 3.8E-39 T 28-03-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CO689_RS10590 602a6a893a88eccf2ccb640132355772 550 Gene3D G3DSA:3.40.120.10 322 437 8.4E-24 T 28-03-2018 CO689_RS10590 602a6a893a88eccf2ccb640132355772 550 SUPERFAMILY SSF53738 290 438 2.79E-23 T 28-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CO689_RS10590 602a6a893a88eccf2ccb640132355772 550 SUPERFAMILY SSF53738 197 298 5.1E-17 T 28-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CO689_RS10590 602a6a893a88eccf2ccb640132355772 550 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 129 138 - T 28-03-2018 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CO689_RS10590 602a6a893a88eccf2ccb640132355772 550 Gene3D G3DSA:3.40.120.10 203 321 1.5E-24 T 28-03-2018 CO689_RS10590 602a6a893a88eccf2ccb640132355772 550 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 128 142 4.5E-7 T 28-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CO689_RS10590 602a6a893a88eccf2ccb640132355772 550 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 215 234 4.5E-7 T 28-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CO689_RS10590 602a6a893a88eccf2ccb640132355772 550 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 282 297 4.5E-7 T 28-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CO689_RS10590 602a6a893a88eccf2ccb640132355772 550 SUPERFAMILY SSF55957 454 537 5.36E-10 T 28-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CO689_RS10590 602a6a893a88eccf2ccb640132355772 550 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 199 299 5.6E-20 T 28-03-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CO689_RS10590 602a6a893a88eccf2ccb640132355772 550 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 310 432 2.1E-13 T 28-03-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CO689_RS10590 602a6a893a88eccf2ccb640132355772 550 SUPERFAMILY SSF53738 30 209 2.09E-42 T 28-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CO689_RS00900 13a53b7682b74a9b8a370bef0294da9f 249 SUPERFAMILY SSF51695 10 244 3.35E-71 T 28-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 CO689_RS00900 13a53b7682b74a9b8a370bef0294da9f 249 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 15 243 1.7E-44 T 28-03-2018 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 CO689_RS00900 13a53b7682b74a9b8a370bef0294da9f 249 Gene3D G3DSA:3.20.20.190 2 247 1.7E-73 T 28-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 CO689_RS06130 53dff72f72d6f8a21909835380dc3b25 451 Pfam PF03611 PTS system sugar-specific permease component 10 406 7.4E-148 T 28-03-2018 IPR004703 Phosphotransferase system, sugar-specific permease component GO:0009401|GO:0016021 CO689_RS07535 611b30b4262248d117e1a23245fdc750 105 SUPERFAMILY SSF82607 11 105 9.42E-34 T 28-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family CO689_RS07535 611b30b4262248d117e1a23245fdc750 105 Gene3D G3DSA:3.30.1310.10 1 105 5.8E-37 T 28-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family CO689_RS07535 611b30b4262248d117e1a23245fdc750 105 PIRSF PIRSF004555 3 105 5.4E-39 T 28-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family CO689_RS07535 611b30b4262248d117e1a23245fdc750 105 TIGRFAM TIGR00103 DNA_YbaB_EbfC: DNA-binding protein, YbaB/EbfC family 4 105 9.0E-31 T 28-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family CO689_RS07535 611b30b4262248d117e1a23245fdc750 105 Pfam PF02575 YbaB/EbfC DNA-binding family 11 101 4.6E-34 T 28-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family CO689_RS07535 611b30b4262248d117e1a23245fdc750 105 Hamap MF_00274 Nucleoid-associated protein YbaB [ybaB]. 5 99 22.986 T 28-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family CO689_RS13495 4cd3db00d9888bce880e3eb9642f7bba 424 Gene3D G3DSA:3.40.50.800 328 421 1.6E-19 T 28-03-2018 IPR004154 Anticodon-binding CO689_RS13495 4cd3db00d9888bce880e3eb9642f7bba 424 Gene3D G3DSA:3.30.930.10 1 327 2.2E-69 T 28-03-2018 CO689_RS13495 4cd3db00d9888bce880e3eb9642f7bba 424 PIRSF PIRSF001549 1 422 1.8E-119 T 28-03-2018 IPR004516 Histidine-tRNA ligase/ATP phosphoribosyltransferase regulatory subunit GO:0005737 CO689_RS13495 4cd3db00d9888bce880e3eb9642f7bba 424 TIGRFAM TIGR00442 hisS: histidine--tRNA ligase 4 410 2.6E-153 T 28-03-2018 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 CO689_RS13495 4cd3db00d9888bce880e3eb9642f7bba 424 Pfam PF03129 Anticodon binding domain 332 420 4.3E-17 T 28-03-2018 IPR004154 Anticodon-binding CO689_RS13495 4cd3db00d9888bce880e3eb9642f7bba 424 SUPERFAMILY SSF52954 329 419 4.08E-24 T 28-03-2018 IPR004154 Anticodon-binding CO689_RS13495 4cd3db00d9888bce880e3eb9642f7bba 424 SUPERFAMILY SSF55681 1 319 6.13E-97 T 28-03-2018 CO689_RS13495 4cd3db00d9888bce880e3eb9642f7bba 424 Hamap MF_00127 Histidine--tRNA ligase [hisS]. 1 420 33.164 T 28-03-2018 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 CO689_RS13495 4cd3db00d9888bce880e3eb9642f7bba 424 Pfam PF13393 Histidyl-tRNA synthetase 7 313 4.5E-47 T 28-03-2018 CO689_RS13720 2823ac9018e4b36f3ea54f8f4e4a207b 445 Pfam PF01488 Shikimate / quinate 5-dehydrogenase 171 305 3.8E-44 T 28-03-2018 IPR006151 Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase CO689_RS13720 2823ac9018e4b36f3ea54f8f4e4a207b 445 PIRSF PIRSF000445 1 433 3.7E-142 T 28-03-2018 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 CO689_RS13720 2823ac9018e4b36f3ea54f8f4e4a207b 445 Pfam PF00745 Glutamyl-tRNAGlu reductase, dimerisation domain 323 418 1.1E-19 T 28-03-2018 IPR015896 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, dimerisation domain GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 CO689_RS13720 2823ac9018e4b36f3ea54f8f4e4a207b 445 Gene3D G3DSA:3.40.50.720 158 320 4.1E-22 T 28-03-2018 CO689_RS13720 2823ac9018e4b36f3ea54f8f4e4a207b 445 TIGRFAM TIGR01035 hemA: glutamyl-tRNA reductase 3 420 3.0E-136 T 28-03-2018 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 CO689_RS13720 2823ac9018e4b36f3ea54f8f4e4a207b 445 SUPERFAMILY SSF69742 1 158 4.97E-44 T 28-03-2018 IPR015895 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, N-terminal GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 CO689_RS13720 2823ac9018e4b36f3ea54f8f4e4a207b 445 Gene3D G3DSA:1.10.1200.70 333 420 5.8E-21 T 28-03-2018 CO689_RS13720 2823ac9018e4b36f3ea54f8f4e4a207b 445 SUPERFAMILY SSF69075 318 420 7.06E-14 T 28-03-2018 IPR015896 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, dimerisation domain GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 CO689_RS13720 2823ac9018e4b36f3ea54f8f4e4a207b 445 Hamap MF_00087 Glutamyl-tRNA reductase [hemA]. 2 417 27.749 T 28-03-2018 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 CO689_RS13720 2823ac9018e4b36f3ea54f8f4e4a207b 445 SUPERFAMILY SSF51735 162 315 4.07E-34 T 28-03-2018 IPR016040 NAD(P)-binding domain CO689_RS13720 2823ac9018e4b36f3ea54f8f4e4a207b 445 Pfam PF05201 Glutamyl-tRNAGlu reductase, N-terminal domain 6 155 5.5E-42 T 28-03-2018 IPR015895 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, N-terminal GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 CO689_RS13720 2823ac9018e4b36f3ea54f8f4e4a207b 445 ProSitePatterns PS00747 Glutamyl-tRNA reductase signature. 99 122 - T 28-03-2018 IPR018214 Glutamyl-tRNA reductase, conserved site GO:0008883|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 CO689_RS08320 972ecc1bebe6018dd1d9aa6d625834d5 158 SUPERFAMILY SSF55729 3 156 6.15E-29 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CO689_RS08320 972ecc1bebe6018dd1d9aa6d625834d5 158 Pfam PF00583 Acetyltransferase (GNAT) family 51 134 7.6E-16 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CO689_RS08320 972ecc1bebe6018dd1d9aa6d625834d5 158 Gene3D G3DSA:3.40.630.30 2 158 2.7E-32 T 28-03-2018 CO689_RS10360 84c998316f00f7e6b3aa12a697aef1a3 254 Pfam PF00977 Histidine biosynthesis protein 5 235 2.3E-79 T 28-03-2018 IPR006062 Histidine biosynthesis GO:0000105 CO689_RS10360 84c998316f00f7e6b3aa12a697aef1a3 254 Hamap MF_01013 Imidazole glycerol phosphate synthase subunit HisF [hisF]. 1 252 44.967 T 28-03-2018 IPR004651 Histidine biosynthesis, HisF GO:0000105|GO:0000107|GO:0005737 CO689_RS10360 84c998316f00f7e6b3aa12a697aef1a3 254 SUPERFAMILY SSF51366 1 253 7.85E-76 T 28-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 CO689_RS10360 84c998316f00f7e6b3aa12a697aef1a3 254 Gene3D G3DSA:3.20.20.70 4 248 6.5E-61 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CO689_RS10360 84c998316f00f7e6b3aa12a697aef1a3 254 TIGRFAM TIGR00735 hisF: imidazoleglycerol phosphate synthase, cyclase subunit 1 252 1.8E-103 T 28-03-2018 IPR004651 Histidine biosynthesis, HisF GO:0000105|GO:0000107|GO:0005737 CO689_RS00520 bdad82f462fad44bfa47b07851a412b2 331 SUPERFAMILY SSF53822 60 329 1.65E-82 T 28-03-2018 IPR028082 Periplasmic binding protein-like I CO689_RS00520 bdad82f462fad44bfa47b07851a412b2 331 Pfam PF13377 Periplasmic binding protein-like domain 165 326 1.6E-36 T 28-03-2018 CO689_RS00520 bdad82f462fad44bfa47b07851a412b2 331 SMART SM00354 1 71 4.7E-25 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CO689_RS00520 bdad82f462fad44bfa47b07851a412b2 331 SUPERFAMILY SSF47413 2 59 2.69E-15 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CO689_RS00520 bdad82f462fad44bfa47b07851a412b2 331 Gene3D G3DSA:3.40.50.2300 58 163 2.0E-24 T 28-03-2018 CO689_RS00520 bdad82f462fad44bfa47b07851a412b2 331 ProSitePatterns PS00356 LacI-type HTH domain signature. 4 22 - T 28-03-2018 CO689_RS00520 bdad82f462fad44bfa47b07851a412b2 331 Gene3D G3DSA:3.40.50.2300 164 328 1.9E-50 T 28-03-2018 CO689_RS00520 bdad82f462fad44bfa47b07851a412b2 331 Pfam PF00356 Bacterial regulatory proteins, lacI family 3 48 2.3E-17 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CO689_RS00520 bdad82f462fad44bfa47b07851a412b2 331 Gene3D G3DSA:1.10.260.40 2 57 1.4E-18 T 28-03-2018 CO689_RS00635 4cb4cc9a119288c5d01a3a203d0cd663 311 Gene3D G3DSA:1.10.10.10 16 109 3.2E-7 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS00635 4cb4cc9a119288c5d01a3a203d0cd663 311 Pfam PF08279 HTH domain 54 87 5.4E-6 T 28-03-2018 IPR013196 Helix-turn-helix, type 11 CO689_RS00635 4cb4cc9a119288c5d01a3a203d0cd663 311 SUPERFAMILY SSF46785 55 86 5.8E-5 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS01315 e86c7687eb08c2229accaae7f749ae9c 467 Pfam PF01593 Flavin containing amine oxidoreductase 14 461 3.0E-61 T 28-03-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 CO689_RS01315 e86c7687eb08c2229accaae7f749ae9c 467 Gene3D G3DSA:3.90.660.20 218 413 1.4E-41 T 28-03-2018 CO689_RS01315 e86c7687eb08c2229accaae7f749ae9c 467 Gene3D G3DSA:3.90.660.20 51 117 1.6E-7 T 28-03-2018 CO689_RS01315 e86c7687eb08c2229accaae7f749ae9c 467 SUPERFAMILY SSF51905 423 464 9.71E-51 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CO689_RS01315 e86c7687eb08c2229accaae7f749ae9c 467 SUPERFAMILY SSF51905 3 320 9.71E-51 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CO689_RS01315 e86c7687eb08c2229accaae7f749ae9c 467 Gene3D G3DSA:3.40.50.720 2 50 4.0E-4 T 28-03-2018 CO689_RS01315 e86c7687eb08c2229accaae7f749ae9c 467 SUPERFAMILY SSF54373 306 413 5.49E-31 T 28-03-2018 CO689_RS01315 e86c7687eb08c2229accaae7f749ae9c 467 Gene3D G3DSA:1.10.3110.10 118 206 1.8E-28 T 28-03-2018 CO689_RS01315 e86c7687eb08c2229accaae7f749ae9c 467 TIGRFAM TIGR00562 proto_IX_ox: protoporphyrinogen oxidase 5 463 4.7E-116 T 28-03-2018 IPR004572 Protoporphyrinogen oxidase GO:0004729|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.4|MetaCyc: PWY-7159|Reactome: R-HSA-189451 CO689_RS11450 3a2977500cf013715481fdb7b7e2383d 434 Gene3D G3DSA:3.30.70.1170 166 232 3.9E-9 T 28-03-2018 CO689_RS11450 3a2977500cf013715481fdb7b7e2383d 434 TIGRFAM TIGR00563 rsmB: 16S rRNA (cytosine(967)-C(5))-methyltransferase 5 432 6.3E-119 T 28-03-2018 IPR004573 rRNA small subunit methyltransferase B GO:0006364|GO:0008649 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CO689_RS11450 3a2977500cf013715481fdb7b7e2383d 434 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 223 237 4.2E-30 T 28-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CO689_RS11450 3a2977500cf013715481fdb7b7e2383d 434 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 252 262 4.2E-30 T 28-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CO689_RS11450 3a2977500cf013715481fdb7b7e2383d 434 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 316 328 4.2E-30 T 28-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CO689_RS11450 3a2977500cf013715481fdb7b7e2383d 434 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 366 382 4.2E-30 T 28-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CO689_RS11450 3a2977500cf013715481fdb7b7e2383d 434 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 414 431 4.2E-30 T 28-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CO689_RS11450 3a2977500cf013715481fdb7b7e2383d 434 SUPERFAMILY SSF53335 134 432 4.45E-70 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CO689_RS11450 3a2977500cf013715481fdb7b7e2383d 434 Pfam PF01029 NusB family 3 124 2.8E-31 T 28-03-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 CO689_RS11450 3a2977500cf013715481fdb7b7e2383d 434 Pfam PF01189 16S rRNA methyltransferase RsmB/F 241 429 1.2E-53 T 28-03-2018 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CO689_RS11450 3a2977500cf013715481fdb7b7e2383d 434 Gene3D G3DSA:1.10.940.10 1 141 1.6E-29 T 28-03-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 CO689_RS11450 3a2977500cf013715481fdb7b7e2383d 434 SUPERFAMILY SSF48013 3 125 1.02E-34 T 28-03-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 CO689_RS11450 3a2977500cf013715481fdb7b7e2383d 434 Gene3D G3DSA:3.40.50.150 233 434 9.4E-57 T 28-03-2018 CO689_RS07285 62e86194e1610f3ffb637b374d2c549d 241 TIGRFAM TIGR00434 cysH: phosophoadenylyl-sulfate reductase 29 236 6.3E-93 T 28-03-2018 IPR004511 Phosphoadenosine phosphosulphate/adenosine 5'-phosphosulphate reductase GO:0004604|GO:0019379|GO:0055114 KEGG: 00920+1.8.4.8 CO689_RS07285 62e86194e1610f3ffb637b374d2c549d 241 Gene3D G3DSA:3.40.50.620 11 241 2.5E-47 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CO689_RS07285 62e86194e1610f3ffb637b374d2c549d 241 TIGRFAM TIGR02055 APS_reductase: adenylylsulfate reductase, thioredoxin dependent 47 235 1.4E-77 T 28-03-2018 IPR011798 Adenosine 5'-phosphosulphate reductase GO:0004604|GO:0019344|GO:0055114 KEGG: 00920+1.8.4.8 CO689_RS07285 62e86194e1610f3ffb637b374d2c549d 241 Hamap MF_00063 Phosphoadenosine phosphosulfate reductase [cysH]. 4 237 42.005 T 28-03-2018 IPR004511 Phosphoadenosine phosphosulphate/adenosine 5'-phosphosulphate reductase GO:0004604|GO:0019379|GO:0055114 KEGG: 00920+1.8.4.8 CO689_RS07285 62e86194e1610f3ffb637b374d2c549d 241 SUPERFAMILY SSF52402 17 200 1.91E-54 T 28-03-2018 CO689_RS07285 62e86194e1610f3ffb637b374d2c549d 241 Pfam PF01507 Phosphoadenosine phosphosulfate reductase family 41 213 2.9E-52 T 28-03-2018 IPR002500 Phosphoadenosine phosphosulphate reductase GO:0003824|GO:0008152 Reactome: R-HSA-196843 CO689_RS07285 62e86194e1610f3ffb637b374d2c549d 241 PIRSF PIRSF000857 3 241 4.0E-92 T 28-03-2018 IPR004511 Phosphoadenosine phosphosulphate/adenosine 5'-phosphosulphate reductase GO:0004604|GO:0019379|GO:0055114 KEGG: 00920+1.8.4.8 CO689_RS09165 09018192cb16e7e969bd90a1acca6bcb 307 SUPERFAMILY SSF52540 12 169 1.05E-11 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CO689_RS09165 09018192cb16e7e969bd90a1acca6bcb 307 Hamap MF_00636 RNase adapter protein RapZ [rapZ]. 12 298 41.31 T 28-03-2018 IPR005337 RapZ-like family GO:0005524 CO689_RS09165 09018192cb16e7e969bd90a1acca6bcb 307 Gene3D G3DSA:3.40.50.300 13 170 1.6E-12 T 28-03-2018 CO689_RS09165 09018192cb16e7e969bd90a1acca6bcb 307 Pfam PF03668 P-loop ATPase protein family 13 295 8.4E-105 T 28-03-2018 IPR005337 RapZ-like family GO:0005524 CO689_RS09165 09018192cb16e7e969bd90a1acca6bcb 307 PIRSF PIRSF005052 12 301 1.7E-111 T 28-03-2018 IPR005337 RapZ-like family GO:0005524 CO689_RS10415 2fd0cdc5786208ee456b2cad983ac37b 486 Pfam PF00005 ABC transporter 19 169 2.6E-21 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CO689_RS10415 2fd0cdc5786208ee456b2cad983ac37b 486 Pfam PF00005 ABC transporter 283 417 1.6E-22 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CO689_RS10415 2fd0cdc5786208ee456b2cad983ac37b 486 SUPERFAMILY SSF52540 2 228 1.03E-49 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CO689_RS10415 2fd0cdc5786208ee456b2cad983ac37b 486 SUPERFAMILY SSF52540 262 471 1.24E-41 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CO689_RS10415 2fd0cdc5786208ee456b2cad983ac37b 486 Gene3D G3DSA:3.40.50.300 1 250 3.1E-53 T 28-03-2018 CO689_RS10415 2fd0cdc5786208ee456b2cad983ac37b 486 Gene3D G3DSA:3.40.50.300 251 474 1.1E-42 T 28-03-2018 CO689_RS10415 2fd0cdc5786208ee456b2cad983ac37b 486 SMART SM00382 28 220 9.5E-9 T 28-03-2018 IPR003593 AAA+ ATPase domain CO689_RS10415 2fd0cdc5786208ee456b2cad983ac37b 486 SMART SM00382 288 465 2.4E-14 T 28-03-2018 IPR003593 AAA+ ATPase domain CO689_RS02350 9629a34484de99856680af14d627241d 68 SUPERFAMILY SSF55008 3 66 2.23E-8 T 28-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 CO689_RS02350 9629a34484de99856680af14d627241d 68 Gene3D G3DSA:3.30.70.100 3 67 1.9E-7 T 28-03-2018 CO689_RS10395 a67080f6776a56542f8b65838bbcb4db 276 Gene3D G3DSA:3.30.930.10 117 275 5.2E-5 T 28-03-2018 CO689_RS10395 a67080f6776a56542f8b65838bbcb4db 276 Pfam PF13393 Histidyl-tRNA synthetase 8 270 1.0E-12 T 28-03-2018 CO689_RS10395 a67080f6776a56542f8b65838bbcb4db 276 SUPERFAMILY SSF55681 10 272 3.48E-8 T 28-03-2018 CO689_RS05050 e26a380a31554d481648b5aa658c0788 120 TIGRFAM TIGR02364 dha_pts: dihydroxyacetone kinase, phosphotransfer subunit 3 116 1.5E-35 T 28-03-2018 IPR012844 Dihydroxyacetone kinase phosphotransferase subunit, N-terminal domain CO689_RS05050 e26a380a31554d481648b5aa658c0788 120 Pfam PF03610 PTS system fructose IIA component 4 111 5.3E-24 T 28-03-2018 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 CO689_RS05050 e26a380a31554d481648b5aa658c0788 120 SUPERFAMILY SSF53062 1 117 9.29E-29 T 28-03-2018 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 CO689_RS05050 e26a380a31554d481648b5aa658c0788 120 Gene3D G3DSA:3.40.50.510 1 120 9.0E-26 T 28-03-2018 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 CO689_RS01060 034e9065e9c3fa2402581e658c865a82 544 Pfam PF01943 Polysaccharide biosynthesis protein 7 325 1.3E-28 T 28-03-2018 IPR002797 Polysaccharide biosynthesis protein GO:0016020 CO689_RS01060 034e9065e9c3fa2402581e658c865a82 544 PIRSF PIRSF038958 2 541 4.7E-96 T 28-03-2018 IPR024923 Peptidoglycan biosynthesis protein, SpoVB-type CO689_RS01060 034e9065e9c3fa2402581e658c865a82 544 Pfam PF14667 Polysaccharide biosynthesis C-terminal domain 378 525 2.1E-26 T 28-03-2018 IPR029303 Polysaccharide biosynthesis protein, C-terminal domain CO689_RS00955 b031dfb429b1dd23c394675aa0c4c66f 570 Gene3D G3DSA:3.40.50.980 41 215 2.5E-40 T 28-03-2018 CO689_RS00955 b031dfb429b1dd23c394675aa0c4c66f 570 Gene3D G3DSA:2.30.38.10 371 453 5.2E-20 T 28-03-2018 CO689_RS00955 b031dfb429b1dd23c394675aa0c4c66f 570 Gene3D G3DSA:3.30.300.30 456 569 9.2E-27 T 28-03-2018 CO689_RS00955 b031dfb429b1dd23c394675aa0c4c66f 570 Pfam PF13193 AMP-binding enzyme C-terminal domain 469 547 1.8E-24 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CO689_RS00955 b031dfb429b1dd23c394675aa0c4c66f 570 SUPERFAMILY SSF56801 18 560 6.28E-162 T 28-03-2018 CO689_RS00955 b031dfb429b1dd23c394675aa0c4c66f 570 ProSitePatterns PS00455 Putative AMP-binding domain signature. 210 221 - T 28-03-2018 IPR020845 AMP-binding, conserved site CO689_RS00955 b031dfb429b1dd23c394675aa0c4c66f 570 Pfam PF00501 AMP-binding enzyme 56 459 1.6E-96 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CO689_RS00955 b031dfb429b1dd23c394675aa0c4c66f 570 Gene3D G3DSA:3.40.50.980 216 370 1.6E-41 T 28-03-2018 CO689_RS11110 0023d545e09ee2519e5e51b288a9aa6d 172 Pfam PF00583 Acetyltransferase (GNAT) family 36 128 4.3E-14 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CO689_RS11110 0023d545e09ee2519e5e51b288a9aa6d 172 Gene3D G3DSA:3.40.630.30 1 157 2.6E-20 T 28-03-2018 CO689_RS11110 0023d545e09ee2519e5e51b288a9aa6d 172 SUPERFAMILY SSF55729 1 137 5.8E-26 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CO689_RS10520 f838dd30e495b1923560fecd7172f2e1 450 TIGRFAM TIGR00543 isochor_syn: isochorismate synthase 103 444 6.2E-114 T 28-03-2018 IPR004561 Isochorismate synthase GO:0008909|GO:0009058 KEGG: 00130+5.4.4.2|MetaCyc: PWY-5837|MetaCyc: PWY-5901|MetaCyc: PWY-6406 CO689_RS10520 f838dd30e495b1923560fecd7172f2e1 450 Pfam PF00425 chorismate binding enzyme 186 436 1.9E-66 T 28-03-2018 IPR015890 Chorismate-utilising enzyme, C-terminal CO689_RS10520 f838dd30e495b1923560fecd7172f2e1 450 Gene3D G3DSA:3.60.120.10 2 447 2.3E-88 T 28-03-2018 IPR005801 ADC synthase GO:0009058 CO689_RS10520 f838dd30e495b1923560fecd7172f2e1 450 SUPERFAMILY SSF56322 37 446 1.31E-89 T 28-03-2018 IPR005801 ADC synthase GO:0009058 CO689_RS03425 aa5e0f96cd83e379f792407fcf73513c 286 Gene3D G3DSA:3.40.1090.10 3 269 3.8E-20 T 28-03-2018 CO689_RS03425 aa5e0f96cd83e379f792407fcf73513c 286 SUPERFAMILY SSF52151 107 232 1.62E-21 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CO689_RS03425 aa5e0f96cd83e379f792407fcf73513c 286 SUPERFAMILY SSF52151 4 76 1.62E-21 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CO689_RS03425 aa5e0f96cd83e379f792407fcf73513c 286 Pfam PF01734 Patatin-like phospholipase 8 195 6.5E-10 T 28-03-2018 IPR002641 Patatin-like phospholipase domain GO:0006629 CO689_RS01885 84154a0540c76402b75be3e6025e13e1 372 Pfam PF12708 Pectate lyase superfamily protein 6 167 8.6E-8 T 28-03-2018 IPR024535 Pectate lyase superfamily protein CO689_RS01885 84154a0540c76402b75be3e6025e13e1 372 SUPERFAMILY SSF51126 3 335 1.08E-35 T 28-03-2018 IPR011050 Pectin lyase fold/virulence factor CO689_RS01885 84154a0540c76402b75be3e6025e13e1 372 Gene3D G3DSA:2.160.20.10 2 356 6.6E-39 T 28-03-2018 IPR012334 Pectin lyase fold CO689_RS02595 490cdfac7459bcec7edad5cc5259b1d1 795 SUPERFAMILY SSF56059 523 713 1.71E-21 T 28-03-2018 CO689_RS02595 490cdfac7459bcec7edad5cc5259b1d1 795 SUPERFAMILY SSF55031 171 277 3.93E-19 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain CO689_RS02595 490cdfac7459bcec7edad5cc5259b1d1 795 SUPERFAMILY SSF53187 284 378 5.91E-58 T 28-03-2018 CO689_RS02595 490cdfac7459bcec7edad5cc5259b1d1 795 SUPERFAMILY SSF53187 7 184 5.91E-58 T 28-03-2018 CO689_RS02595 490cdfac7459bcec7edad5cc5259b1d1 795 Gene3D G3DSA:3.40.630.10 1 394 9.5E-60 T 28-03-2018 CO689_RS02595 490cdfac7459bcec7edad5cc5259b1d1 795 Pfam PF07687 Peptidase dimerisation domain 174 262 7.8E-7 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain CO689_RS02595 490cdfac7459bcec7edad5cc5259b1d1 795 Gene3D G3DSA:3.30.470.20 517 719 2.7E-18 T 28-03-2018 CO689_RS02595 490cdfac7459bcec7edad5cc5259b1d1 795 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 19 335 4.2E-60 T 28-03-2018 IPR017439 Amidohydrolase GO:0016787 CO689_RS08215 b3d2ca0e934b79ee92a0d43dd9c558c1 257 SUPERFAMILY SSF52540 4 241 9.9E-64 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CO689_RS08215 b3d2ca0e934b79ee92a0d43dd9c558c1 257 TIGRFAM TIGR02315 ABC_phnC: phosphonate ABC transporter, ATP-binding protein 4 245 3.4E-109 T 28-03-2018 IPR012693 ABC transporter, phosphonate import, PhnC GO:0005524|GO:0015416|GO:0015716|GO:0016020 CO689_RS08215 b3d2ca0e934b79ee92a0d43dd9c558c1 257 ProSitePatterns PS00211 ABC transporters family signature. 148 162 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CO689_RS08215 b3d2ca0e934b79ee92a0d43dd9c558c1 257 SMART SM00382 29 225 6.1E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain CO689_RS08215 b3d2ca0e934b79ee92a0d43dd9c558c1 257 Pfam PF00005 ABC transporter 20 176 3.5E-33 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CO689_RS08215 b3d2ca0e934b79ee92a0d43dd9c558c1 257 Gene3D G3DSA:3.40.50.300 1 252 8.0E-59 T 28-03-2018 CO689_RS07755 b72a7129fd4a53d59b53c72d53a7bdff 125 Pfam PF04977 Septum formation initiator 41 118 3.4E-17 T 28-03-2018 IPR007060 Septum formation initiator FtsL/DivIC GO:0007049 CO689_RS11620 71f2a8f70e5b00e1ffe5826c8ba2524c 289 SUPERFAMILY SSF52540 9 259 2.83E-50 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CO689_RS11620 71f2a8f70e5b00e1ffe5826c8ba2524c 289 Gene3D G3DSA:3.40.50.300 12 179 3.6E-34 T 28-03-2018 CO689_RS11620 71f2a8f70e5b00e1ffe5826c8ba2524c 289 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 169 184 6.2E-6 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CO689_RS11620 71f2a8f70e5b00e1ffe5826c8ba2524c 289 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 123 143 6.2E-6 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CO689_RS11620 71f2a8f70e5b00e1ffe5826c8ba2524c 289 Gene3D G3DSA:1.10.1580.10 180 273 1.6E-19 T 28-03-2018 IPR023179 GTP-binding protein, orthogonal bundle domain CO689_RS11620 71f2a8f70e5b00e1ffe5826c8ba2524c 289 Pfam PF01926 50S ribosome-binding GTPase 123 215 1.5E-18 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CO689_RS11620 71f2a8f70e5b00e1ffe5826c8ba2524c 289 PIRSF PIRSF006230 1 284 1.6E-99 T 28-03-2018 IPR016478 GTPase, MTG1 CO689_RS11620 71f2a8f70e5b00e1ffe5826c8ba2524c 289 TIGRFAM TIGR03596 GTPase_YlqF: ribosome biogenesis GTP-binding protein YlqF 3 279 7.5E-113 T 28-03-2018 IPR019991 GTP-binding protein, ribosome biogenesis CO689_RS02650 92c107cd07d59b5e60ed2e003d873920 230 Hamap MF_02104 Lactate utilization protein C [lutC]. 4 227 43.254 T 28-03-2018 IPR022823 Lactate utilization protein C CO689_RS02650 92c107cd07d59b5e60ed2e003d873920 230 SUPERFAMILY SSF100950 44 228 1.0E-40 T 28-03-2018 CO689_RS02650 92c107cd07d59b5e60ed2e003d873920 230 Gene3D G3DSA:3.40.50.10420 43 228 1.5E-41 T 28-03-2018 CO689_RS02650 92c107cd07d59b5e60ed2e003d873920 230 Pfam PF02589 LUD domain 101 227 4.1E-30 T 28-03-2018 IPR003741 LUD domain CO689_RS02680 27607702558edb783e17ffb2098d22f1 313 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 19 297 2.8E-93 T 28-03-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 CO689_RS02680 27607702558edb783e17ffb2098d22f1 313 Pfam PF01545 Cation efflux family 25 216 2.3E-52 T 28-03-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 CO689_RS02680 27607702558edb783e17ffb2098d22f1 313 Gene3D G3DSA:3.30.70.1350 218 299 4.4E-14 T 28-03-2018 IPR027470 Cation efflux protein, cytoplasmic domain CO689_RS02680 27607702558edb783e17ffb2098d22f1 313 SUPERFAMILY SSF160240 220 295 2.62E-11 T 28-03-2018 CO689_RS02680 27607702558edb783e17ffb2098d22f1 313 SUPERFAMILY SSF161111 19 217 6.15E-60 T 28-03-2018 CO689_RS02680 27607702558edb783e17ffb2098d22f1 313 Gene3D G3DSA:1.20.1510.10 18 216 2.4E-59 T 28-03-2018 CO689_RS02815 77c6d86f510181264bae5b1deba614ce 171 Pfam PF04307 LexA-binding, inner membrane-associated putative hydrolase 1 159 4.6E-31 T 28-03-2018 IPR007404 LexA-binding, inner membrane-associated putative hydrolase CO689_RS04815 39c178b957cd468c9c56d551510e79a4 415 ProSitePatterns PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. 74 83 - T 28-03-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 CO689_RS04815 39c178b957cd468c9c56d551510e79a4 415 TIGRFAM TIGR01879 hydantase: amidase, hydantoinase/carbamoylase family 7 406 1.9E-127 T 28-03-2018 IPR010158 Amidase, carbamoylase-type GO:0008152|GO:0016813 CO689_RS04815 39c178b957cd468c9c56d551510e79a4 415 Gene3D G3DSA:3.40.630.10 254 411 1.2E-20 T 28-03-2018 CO689_RS04815 39c178b957cd468c9c56d551510e79a4 415 Gene3D G3DSA:3.40.630.10 1 253 7.3E-36 T 28-03-2018 CO689_RS04815 39c178b957cd468c9c56d551510e79a4 415 Pfam PF07687 Peptidase dimerisation domain 215 312 5.2E-7 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain CO689_RS04815 39c178b957cd468c9c56d551510e79a4 415 PIRSF PIRSF001235 2 411 1.1E-134 T 28-03-2018 IPR010158 Amidase, carbamoylase-type GO:0008152|GO:0016813 CO689_RS04815 39c178b957cd468c9c56d551510e79a4 415 SUPERFAMILY SSF55031 213 321 5.5E-24 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain CO689_RS04815 39c178b957cd468c9c56d551510e79a4 415 Pfam PF01546 Peptidase family M20/M25/M40 75 404 3.2E-32 T 28-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CO689_RS04815 39c178b957cd468c9c56d551510e79a4 415 SUPERFAMILY SSF53187 335 411 3.02E-76 T 28-03-2018 CO689_RS04815 39c178b957cd468c9c56d551510e79a4 415 SUPERFAMILY SSF53187 15 221 3.02E-76 T 28-03-2018 CO689_RS01655 b9589e02d94597a80418da2bd5530917 508 Gene3D G3DSA:3.40.50.300 6 275 3.7E-23 T 28-03-2018 CO689_RS01655 b9589e02d94597a80418da2bd5530917 508 Pfam PF00005 ABC transporter 37 139 3.9E-10 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CO689_RS01655 b9589e02d94597a80418da2bd5530917 508 SUPERFAMILY SSF52540 33 228 6.94E-22 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CO689_RS01655 b9589e02d94597a80418da2bd5530917 508 SMART SM00382 46 204 3.0E-4 T 28-03-2018 IPR003593 AAA+ ATPase domain CO689_RS03540 7a4c09de623a7877504c1d70c762a860 228 SMART SM00420 6 62 0.0034 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CO689_RS03540 7a4c09de623a7877504c1d70c762a860 228 Pfam PF08279 HTH domain 6 61 4.2E-15 T 28-03-2018 IPR013196 Helix-turn-helix, type 11 CO689_RS03540 7a4c09de623a7877504c1d70c762a860 228 SUPERFAMILY SSF46785 3 62 1.15E-9 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS03540 7a4c09de623a7877504c1d70c762a860 228 Gene3D G3DSA:1.10.10.10 1 64 7.9E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS00815 09cf56362a12ecc1338e883921e56fa3 87 Gene3D G3DSA:2.60.40.1280 2 87 2.5E-20 T 28-03-2018 IPR011252 Fibrogen-binding domain 1 GO:0005618|GO:0007155 CO689_RS00815 09cf56362a12ecc1338e883921e56fa3 87 SUPERFAMILY SSF49401 3 80 3.23E-19 T 28-03-2018 IPR008966 Adhesion domain CO689_RS10040 ab4e23f78c67ff61145a5f7cc204596e 3368 Gene3D G3DSA:2.60.120.200 328 564 3.5E-20 T 28-03-2018 CO689_RS10040 ab4e23f78c67ff61145a5f7cc204596e 3368 Pfam PF07554 FIVAR domain 1589 1646 0.01 T 28-03-2018 CO689_RS10040 ab4e23f78c67ff61145a5f7cc204596e 3368 Pfam PF07554 FIVAR domain 2274 2335 0.11 T 28-03-2018 CO689_RS10040 ab4e23f78c67ff61145a5f7cc204596e 3368 Pfam PF07554 FIVAR domain 1110 1171 0.47 T 28-03-2018 CO689_RS10040 ab4e23f78c67ff61145a5f7cc204596e 3368 Pfam PF07554 FIVAR domain 2352 2413 0.14 T 28-03-2018 CO689_RS10040 ab4e23f78c67ff61145a5f7cc204596e 3368 Pfam PF07554 FIVAR domain 3055 3116 0.003 T 28-03-2018 CO689_RS10040 ab4e23f78c67ff61145a5f7cc204596e 3368 Pfam PF07554 FIVAR domain 1719 1780 0.017 T 28-03-2018 CO689_RS10040 ab4e23f78c67ff61145a5f7cc204596e 3368 Pfam PF07554 FIVAR domain 3200 3261 5.8E-4 T 28-03-2018 CO689_RS10040 ab4e23f78c67ff61145a5f7cc204596e 3368 Pfam PF07554 FIVAR domain 1319 1378 0.0063 T 28-03-2018 CO689_RS10040 ab4e23f78c67ff61145a5f7cc204596e 3368 Pfam PF07554 FIVAR domain 2419 2479 0.053 T 28-03-2018 CO689_RS10040 ab4e23f78c67ff61145a5f7cc204596e 3368 Pfam PF07554 FIVAR domain 1518 1571 0.36 T 28-03-2018 CO689_RS10040 ab4e23f78c67ff61145a5f7cc204596e 3368 Pfam PF07554 FIVAR domain 2487 2547 0.066 T 28-03-2018 CO689_RS10040 ab4e23f78c67ff61145a5f7cc204596e 3368 Pfam PF07554 FIVAR domain 1253 1314 0.35 T 28-03-2018 CO689_RS10040 ab4e23f78c67ff61145a5f7cc204596e 3368 Pfam PF07554 FIVAR domain 1932 1993 0.0043 T 28-03-2018 CO689_RS10040 ab4e23f78c67ff61145a5f7cc204596e 3368 Pfam PF07554 FIVAR domain 949 1024 5.7E-5 T 28-03-2018 CO689_RS10040 ab4e23f78c67ff61145a5f7cc204596e 3368 Pfam PF07554 FIVAR domain 1797 1858 0.016 T 28-03-2018 CO689_RS10040 ab4e23f78c67ff61145a5f7cc204596e 3368 Pfam PF07554 FIVAR domain 1863 1924 0.0085 T 28-03-2018 CO689_RS10040 ab4e23f78c67ff61145a5f7cc204596e 3368 Pfam PF07554 FIVAR domain 2773 2831 0.013 T 28-03-2018 CO689_RS10040 ab4e23f78c67ff61145a5f7cc204596e 3368 Pfam PF07554 FIVAR domain 1652 1715 2.2E-4 T 28-03-2018 CO689_RS10040 ab4e23f78c67ff61145a5f7cc204596e 3368 Pfam PF07554 FIVAR domain 2209 2270 2.2E-5 T 28-03-2018 CO689_RS10040 ab4e23f78c67ff61145a5f7cc204596e 3368 Pfam PF07554 FIVAR domain 1029 1090 6.7E-4 T 28-03-2018 CO689_RS10040 ab4e23f78c67ff61145a5f7cc204596e 3368 Pfam PF07554 FIVAR domain 2914 2975 0.023 T 28-03-2018 CO689_RS10040 ab4e23f78c67ff61145a5f7cc204596e 3368 Pfam PF07554 FIVAR domain 1388 1448 0.009 T 28-03-2018 CO689_RS10040 ab4e23f78c67ff61145a5f7cc204596e 3368 Pfam PF07554 FIVAR domain 2627 2688 0.0058 T 28-03-2018 CO689_RS10040 ab4e23f78c67ff61145a5f7cc204596e 3368 Pfam PF07554 FIVAR domain 2140 2200 0.032 T 28-03-2018 CO689_RS10040 ab4e23f78c67ff61145a5f7cc204596e 3368 Pfam PF07554 FIVAR domain 1451 1511 0.0012 T 28-03-2018 CO689_RS10040 ab4e23f78c67ff61145a5f7cc204596e 3368 TIGRFAM TIGR01168 YSIRK_signal: gram-positive signal peptide, YSIRK family 8 45 2.9E-12 T 28-03-2018 IPR005877 YSIRK Gram-positive signal peptide GO:0016020 CO689_RS10040 ab4e23f78c67ff61145a5f7cc204596e 3368 ProDom PD968187 BETA-DEFENSIN ANTIBIOTIC PRECURSOR ANTIMICROBIAL DEFENSIN BETA SIGNAL DEFENSIN BD-32 DEFB-32 2513 3155 5.0E-6 T 28-03-2018 CO689_RS10040 ab4e23f78c67ff61145a5f7cc204596e 3368 Gene3D G3DSA:1.20.1270.90 2351 2415 5.3E-6 T 28-03-2018 CO689_RS10040 ab4e23f78c67ff61145a5f7cc204596e 3368 Gene3D G3DSA:1.20.1270.90 2979 3040 1.4E-7 T 28-03-2018 CO689_RS10040 ab4e23f78c67ff61145a5f7cc204596e 3368 Gene3D G3DSA:1.20.1270.90 1174 1236 0.0026 T 28-03-2018 CO689_RS10040 ab4e23f78c67ff61145a5f7cc204596e 3368 Gene3D G3DSA:1.20.1270.90 2838 2899 9.0E-8 T 28-03-2018 CO689_RS10040 ab4e23f78c67ff61145a5f7cc204596e 3368 Gene3D G3DSA:1.20.1270.90 3122 3181 3.5E-6 T 28-03-2018 CO689_RS10040 ab4e23f78c67ff61145a5f7cc204596e 3368 Gene3D G3DSA:1.20.1270.90 2700 2753 3.7E-4 T 28-03-2018 CO689_RS10040 ab4e23f78c67ff61145a5f7cc204596e 3368 Gene3D G3DSA:1.20.1270.90 2280 2335 9.1E-6 T 28-03-2018 CO689_RS10040 ab4e23f78c67ff61145a5f7cc204596e 3368 Gene3D G3DSA:1.20.1270.90 2550 2614 2.6E-4 T 28-03-2018 CO689_RS10040 ab4e23f78c67ff61145a5f7cc204596e 3368 Gene3D G3DSA:1.20.1270.90 1450 1511 5.3E-5 T 28-03-2018 CO689_RS10040 ab4e23f78c67ff61145a5f7cc204596e 3368 Gene3D G3DSA:1.20.1270.90 1027 1090 3.6E-6 T 28-03-2018 CO689_RS10040 ab4e23f78c67ff61145a5f7cc204596e 3368 Gene3D G3DSA:1.20.1270.90 886 952 6.6E-5 T 28-03-2018 CO689_RS10040 ab4e23f78c67ff61145a5f7cc204596e 3368 Gene3D G3DSA:1.20.1270.90 953 1025 3.2E-9 T 28-03-2018 CO689_RS10040 ab4e23f78c67ff61145a5f7cc204596e 3368 Gene3D G3DSA:1.20.1270.90 1514 1583 3.1E-7 T 28-03-2018 CO689_RS10040 ab4e23f78c67ff61145a5f7cc204596e 3368 Gene3D G3DSA:1.20.1270.90 1656 1716 5.7E-9 T 28-03-2018 CO689_RS10040 ab4e23f78c67ff61145a5f7cc204596e 3368 Pfam PF05345 Putative Ig domain 678 712 3.4E-6 T 28-03-2018 IPR008009 Putative Ig CO689_RS10040 ab4e23f78c67ff61145a5f7cc204596e 3368 Pfam PF05345 Putative Ig domain 764 802 2.9E-10 T 28-03-2018 IPR008009 Putative Ig CO689_RS10040 ab4e23f78c67ff61145a5f7cc204596e 3368 Gene3D G3DSA:1.20.5.420 91 146 8.2E-6 T 28-03-2018 CO689_RS10040 ab4e23f78c67ff61145a5f7cc204596e 3368 Pfam PF00746 LPXTG cell wall anchor motif 3321 3362 4.3E-4 T 28-03-2018 IPR019948 Gram-positive LPXTG cell wall anchor CO689_RS10040 ab4e23f78c67ff61145a5f7cc204596e 3368 Gene3D G3DSA:1.20.1270.70 2906 2978 2.4E-6 T 28-03-2018 CO689_RS10040 ab4e23f78c67ff61145a5f7cc204596e 3368 Gene3D G3DSA:1.20.1270.70 2066 2138 0.033 T 28-03-2018 CO689_RS10040 ab4e23f78c67ff61145a5f7cc204596e 3368 Gene3D G3DSA:1.20.1270.70 2765 2837 9.0E-6 T 28-03-2018 CO689_RS10040 ab4e23f78c67ff61145a5f7cc204596e 3368 Gene3D G3DSA:1.20.1270.70 1384 1449 8.4E-8 T 28-03-2018 CO689_RS10040 ab4e23f78c67ff61145a5f7cc204596e 3368 SUPERFAMILY SSF49313 647 729 1.05E-9 T 28-03-2018 IPR015919 Cadherin-like GO:0005509|GO:0016020 CO689_RS10040 ab4e23f78c67ff61145a5f7cc204596e 3368 Gene3D G3DSA:1.20.1270.90 1795 1860 1.6E-6 T 28-03-2018 CO689_RS10040 ab4e23f78c67ff61145a5f7cc204596e 3368 Gene3D G3DSA:1.20.1270.90 819 885 1.3E-6 T 28-03-2018 CO689_RS10040 ab4e23f78c67ff61145a5f7cc204596e 3368 Gene3D G3DSA:1.20.1270.90 1249 1316 7.8E-8 T 28-03-2018 CO689_RS10040 ab4e23f78c67ff61145a5f7cc204596e 3368 Gene3D G3DSA:1.20.1270.90 1996 2058 1.0E-5 T 28-03-2018 CO689_RS10040 ab4e23f78c67ff61145a5f7cc204596e 3368 Gene3D G3DSA:1.20.1270.90 1717 1780 1.7E-7 T 28-03-2018 CO689_RS10040 ab4e23f78c67ff61145a5f7cc204596e 3368 Gene3D G3DSA:1.20.1270.90 1106 1173 3.6E-7 T 28-03-2018 CO689_RS10040 ab4e23f78c67ff61145a5f7cc204596e 3368 Gene3D G3DSA:1.20.1270.90 2486 2548 3.9E-6 T 28-03-2018 CO689_RS10040 ab4e23f78c67ff61145a5f7cc204596e 3368 Gene3D G3DSA:1.20.1270.90 2139 2207 2.3E-7 T 28-03-2018 CO689_RS10040 ab4e23f78c67ff61145a5f7cc204596e 3368 Gene3D G3DSA:1.20.1270.90 1861 1930 1.1E-7 T 28-03-2018 CO689_RS10040 ab4e23f78c67ff61145a5f7cc204596e 3368 Gene3D G3DSA:1.20.1270.90 3198 3299 5.6E-9 T 28-03-2018 CO689_RS10040 ab4e23f78c67ff61145a5f7cc204596e 3368 Gene3D G3DSA:1.20.1270.90 2208 2279 4.4E-10 T 28-03-2018 CO689_RS10040 ab4e23f78c67ff61145a5f7cc204596e 3368 Gene3D G3DSA:1.20.1270.90 2416 2485 7.6E-8 T 28-03-2018 CO689_RS10040 ab4e23f78c67ff61145a5f7cc204596e 3368 Gene3D G3DSA:1.20.1270.90 1584 1655 1.1E-6 T 28-03-2018 CO689_RS10040 ab4e23f78c67ff61145a5f7cc204596e 3368 Gene3D G3DSA:1.20.1270.90 2625 2699 4.6E-9 T 28-03-2018 CO689_RS10040 ab4e23f78c67ff61145a5f7cc204596e 3368 Gene3D G3DSA:1.20.1270.90 1931 1995 6.0E-8 T 28-03-2018 CO689_RS10040 ab4e23f78c67ff61145a5f7cc204596e 3368 Gene3D G3DSA:1.20.1270.90 1317 1383 4.4E-8 T 28-03-2018 CO689_RS10040 ab4e23f78c67ff61145a5f7cc204596e 3368 Gene3D G3DSA:2.60.40.10 630 727 4.0E-11 T 28-03-2018 IPR013783 Immunoglobulin-like fold CO689_RS10040 ab4e23f78c67ff61145a5f7cc204596e 3368 Gene3D G3DSA:2.60.40.10 728 817 5.9E-13 T 28-03-2018 IPR013783 Immunoglobulin-like fold CO689_RS10040 ab4e23f78c67ff61145a5f7cc204596e 3368 SUPERFAMILY SSF49313 733 817 5.81E-11 T 28-03-2018 IPR015919 Cadherin-like GO:0005509|GO:0016020 CO689_RS10040 ab4e23f78c67ff61145a5f7cc204596e 3368 Gene3D G3DSA:1.20.1270.90 3047 3121 2.6E-6 T 28-03-2018 CO689_RS10040 ab4e23f78c67ff61145a5f7cc204596e 3368 Pfam PF04650 YSIRK type signal peptide 11 34 1.0E-10 T 28-03-2018 IPR005877 YSIRK Gram-positive signal peptide GO:0016020 CO689_RS10040 ab4e23f78c67ff61145a5f7cc204596e 3368 SUPERFAMILY SSF49899 329 552 1.14E-11 T 28-03-2018 IPR013320 Concanavalin A-like lectin/glucanase domain CO689_RS07960 647413c685d08b1f22e9acc797466d9f 456 Pfam PF13541 Subunit ChlI of Mg-chelatase 356 427 5.5E-8 T 28-03-2018 CO689_RS07960 647413c685d08b1f22e9acc797466d9f 456 SUPERFAMILY SSF52540 65 290 2.1E-52 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CO689_RS07960 647413c685d08b1f22e9acc797466d9f 456 Hamap MF_01498 DNA repair protein RadA [radA]. 21 453 43.929 T 28-03-2018 IPR004504 DNA repair protein RadA GO:0003684|GO:0005524|GO:0006281 CO689_RS07960 647413c685d08b1f22e9acc797466d9f 456 Gene3D G3DSA:3.40.50.300 65 258 7.3E-22 T 28-03-2018 CO689_RS07960 647413c685d08b1f22e9acc797466d9f 456 SUPERFAMILY SSF54211 252 266 3.15E-41 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CO689_RS07960 647413c685d08b1f22e9acc797466d9f 456 SUPERFAMILY SSF54211 300 453 3.15E-41 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CO689_RS07960 647413c685d08b1f22e9acc797466d9f 456 Pfam PF13481 AAA domain 72 219 1.2E-14 T 28-03-2018 CO689_RS07960 647413c685d08b1f22e9acc797466d9f 456 TIGRFAM TIGR00416 sms: DNA repair protein RadA 1 449 3.2E-201 T 28-03-2018 IPR004504 DNA repair protein RadA GO:0003684|GO:0005524|GO:0006281 CO689_RS07960 647413c685d08b1f22e9acc797466d9f 456 Gene3D G3DSA:3.30.230.10 259 456 2.9E-36 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CO689_RS07960 647413c685d08b1f22e9acc797466d9f 456 SMART SM00382 88 241 1.2E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain CO689_RS07960 647413c685d08b1f22e9acc797466d9f 456 PRINTS PR01874 DNA repair protein radA signature 210 238 6.2E-93 T 28-03-2018 CO689_RS07960 647413c685d08b1f22e9acc797466d9f 456 PRINTS PR01874 DNA repair protein radA signature 80 108 6.2E-93 T 28-03-2018 CO689_RS07960 647413c685d08b1f22e9acc797466d9f 456 PRINTS PR01874 DNA repair protein radA signature 171 195 6.2E-93 T 28-03-2018 CO689_RS07960 647413c685d08b1f22e9acc797466d9f 456 PRINTS PR01874 DNA repair protein radA signature 319 342 6.2E-93 T 28-03-2018 CO689_RS07960 647413c685d08b1f22e9acc797466d9f 456 PRINTS PR01874 DNA repair protein radA signature 121 138 6.2E-93 T 28-03-2018 CO689_RS07960 647413c685d08b1f22e9acc797466d9f 456 PRINTS PR01874 DNA repair protein radA signature 10 34 6.2E-93 T 28-03-2018 CO689_RS07960 647413c685d08b1f22e9acc797466d9f 456 PRINTS PR01874 DNA repair protein radA signature 245 271 6.2E-93 T 28-03-2018 CO689_RS09970 14689be155862bed4b89fd3b72d2994c 124 SUPERFAMILY SSF54637 4 123 8.36E-30 T 28-03-2018 IPR029069 HotDog domain CO689_RS09970 14689be155862bed4b89fd3b72d2994c 124 Pfam PF03061 Thioesterase superfamily 34 111 6.3E-15 T 28-03-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 CO689_RS09970 14689be155862bed4b89fd3b72d2994c 124 TIGRFAM TIGR00369 unchar_dom_1: uncharacterized domain 1 4 119 1.4E-30 T 28-03-2018 IPR003736 Phenylacetic acid degradation-related domain Reactome: R-HSA-77289 CO689_RS09970 14689be155862bed4b89fd3b72d2994c 124 Gene3D G3DSA:3.10.129.10 2 124 2.0E-23 T 28-03-2018 CO689_RS12165 b43cae2520bc23e6bc778492c4a764f0 227 Gene3D G3DSA:3.30.200.20 1 100 1.1E-19 T 28-03-2018 CO689_RS12165 b43cae2520bc23e6bc778492c4a764f0 227 SUPERFAMILY SSF56104 1 214 1.01E-50 T 28-03-2018 CO689_RS12165 b43cae2520bc23e6bc778492c4a764f0 227 Pfam PF01259 SAICAR synthetase 4 214 3.3E-33 T 28-03-2018 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CO689_RS12165 b43cae2520bc23e6bc778492c4a764f0 227 Hamap MF_00137 Phosphoribosylaminoimidazole-succinocarboxamide synthase [purC]. 1 225 18.985 T 28-03-2018 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CO689_RS12165 b43cae2520bc23e6bc778492c4a764f0 227 Gene3D G3DSA:3.30.470.20 101 221 8.6E-29 T 28-03-2018 CO689_RS09380 28aa13304c2c9001fd434e038fbaf742 229 Gene3D G3DSA:2.60.40.1240 92 229 4.1E-19 T 28-03-2018 IPR029050 Immunoprotective extracellular, immunoglobulin-like domain CO689_RS09380 28aa13304c2c9001fd434e038fbaf742 229 Pfam PF11611 Domain of unknown function (DUF4352) 94 221 1.7E-19 T 28-03-2018 IPR029051 Domain of unknown function DUF4352 CO689_RS01850 30c7769667f8d39b57dc87f8cad51980 281 Hamap MF_00193 NH(3)-dependent NAD(+) synthetase [nadE]. 19 268 29.864 T 28-03-2018 IPR022926 NH(3)-dependent NAD(+) synthetase GO:0008795|GO:0009435 KEGG: 00760+6.3.1.5 CO689_RS01850 30c7769667f8d39b57dc87f8cad51980 281 SUPERFAMILY SSF52402 5 270 3.7E-79 T 28-03-2018 CO689_RS01850 30c7769667f8d39b57dc87f8cad51980 281 Pfam PF02540 NAD synthase 25 264 4.9E-70 T 28-03-2018 IPR022310 NAD/GMP synthase CO689_RS01850 30c7769667f8d39b57dc87f8cad51980 281 Gene3D G3DSA:3.40.50.620 4 272 4.5E-58 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CO689_RS01850 30c7769667f8d39b57dc87f8cad51980 281 TIGRFAM TIGR00552 nadE: NAD+ synthetase 23 264 4.1E-71 T 28-03-2018 IPR003694 NAD(+) synthetase GO:0003952|GO:0005524|GO:0009435 KEGG: 00760+6.3.1.5|Reactome: R-HSA-196807 CO689_RS10370 5282be98fe2b59fda84cdf79e316adbe 193 SUPERFAMILY SSF52317 2 186 8.41E-47 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CO689_RS10370 5282be98fe2b59fda84cdf79e316adbe 193 Gene3D G3DSA:3.40.50.880 1 189 7.6E-36 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CO689_RS10370 5282be98fe2b59fda84cdf79e316adbe 193 TIGRFAM TIGR01855 IMP_synth_hisH: imidazole glycerol phosphate synthase, glutamine amidotransferase subunit 2 186 5.0E-64 T 28-03-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 CO689_RS10370 5282be98fe2b59fda84cdf79e316adbe 193 PIRSF PIRSF000495 1 189 2.2E-66 T 28-03-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 CO689_RS10370 5282be98fe2b59fda84cdf79e316adbe 193 Hamap MF_00278 Imidazole glycerol phosphate synthase subunit HisH [hisH]. 1 188 33.822 T 28-03-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 CO689_RS10370 5282be98fe2b59fda84cdf79e316adbe 193 Pfam PF00117 Glutamine amidotransferase class-I 4 175 5.1E-17 T 28-03-2018 IPR017926 Glutamine amidotransferase CO689_RS08745 351fc985ef41a0f8b80b6af9ab5aadf8 546 SUPERFAMILY SSF90123 2 309 4.05E-45 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CO689_RS08745 351fc985ef41a0f8b80b6af9ab5aadf8 546 ProSitePatterns PS00211 ABC transporters family signature. 453 467 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CO689_RS08745 351fc985ef41a0f8b80b6af9ab5aadf8 546 Gene3D G3DSA:1.20.1560.10 1 308 1.3E-34 T 28-03-2018 CO689_RS08745 351fc985ef41a0f8b80b6af9ab5aadf8 546 Pfam PF00005 ABC transporter 343 480 8.9E-25 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CO689_RS08745 351fc985ef41a0f8b80b6af9ab5aadf8 546 SUPERFAMILY SSF52540 320 530 2.09E-57 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CO689_RS08745 351fc985ef41a0f8b80b6af9ab5aadf8 546 SMART SM00382 352 527 4.9E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain CO689_RS08745 351fc985ef41a0f8b80b6af9ab5aadf8 546 Pfam PF00664 ABC transporter transmembrane region 17 269 2.8E-20 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CO689_RS08745 351fc985ef41a0f8b80b6af9ab5aadf8 546 Gene3D G3DSA:3.40.50.300 309 544 1.3E-54 T 28-03-2018 CO689_RS03640 2a52ec2a64345726e3dc98facf2d3e0f 452 Pfam PF07670 Nucleoside recognition 146 236 4.2E-8 T 28-03-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 CO689_RS13500 05c941c41223077f4feeafe7f31a00ac 291 SUPERFAMILY SSF53187 119 289 7.85E-43 T 28-03-2018 CO689_RS13500 05c941c41223077f4feeafe7f31a00ac 291 SMART SM00287 43 105 1.1E-6 T 28-03-2018 IPR003646 SH3-like domain, bacterial-type CO689_RS13500 05c941c41223077f4feeafe7f31a00ac 291 Gene3D G3DSA:3.40.630.40 117 291 3.4E-47 T 28-03-2018 CO689_RS13500 05c941c41223077f4feeafe7f31a00ac 291 SMART SM00646 178 286 1.2E-31 T 28-03-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 CO689_RS13500 05c941c41223077f4feeafe7f31a00ac 291 Gene3D G3DSA:2.40.50.110 36 103 5.2E-8 T 28-03-2018 CO689_RS13500 05c941c41223077f4feeafe7f31a00ac 291 Pfam PF01520 N-acetylmuramoyl-L-alanine amidase 122 285 3.0E-41 T 28-03-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 CO689_RS06640 1e16a98fd1331daef289cbb2e5acb915 71 SUPERFAMILY SSF51735 34 70 2.1E-13 T 28-03-2018 IPR016040 NAD(P)-binding domain CO689_RS06640 1e16a98fd1331daef289cbb2e5acb915 71 Gene3D G3DSA:3.40.50.720 5 71 2.6E-15 T 28-03-2018 CO689_RS06640 1e16a98fd1331daef289cbb2e5acb915 71 Pfam PF00106 short chain dehydrogenase 38 70 1.9E-9 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CO689_RS06960 38505c557e0693aaa53a279d28b3e6a4 149 Pfam PF03948 Ribosomal protein L9, C-terminal domain 63 146 5.8E-27 T 28-03-2018 IPR020069 Ribosomal protein L9, C-terminal CO689_RS06960 38505c557e0693aaa53a279d28b3e6a4 149 ProSitePatterns PS00651 Ribosomal protein L9 signature. 13 40 - T 28-03-2018 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CO689_RS06960 38505c557e0693aaa53a279d28b3e6a4 149 TIGRFAM TIGR00158 L9: ribosomal protein bL9 1 147 4.6E-42 T 28-03-2018 IPR020594 Ribosomal protein L9, bacteria/chloroplast GO:0003735|GO:0005622|GO:0005840|GO:0006412 CO689_RS06960 38505c557e0693aaa53a279d28b3e6a4 149 Gene3D G3DSA:3.40.5.10 1 49 5.5E-23 T 28-03-2018 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CO689_RS06960 38505c557e0693aaa53a279d28b3e6a4 149 Gene3D G3DSA:3.10.430.100 63 147 6.0E-28 T 28-03-2018 IPR020069 Ribosomal protein L9, C-terminal CO689_RS06960 38505c557e0693aaa53a279d28b3e6a4 149 SUPERFAMILY SSF55658 1 56 9.24E-17 T 28-03-2018 IPR009027 Ribosomal protein L9/RNase H1, N-terminal CO689_RS06960 38505c557e0693aaa53a279d28b3e6a4 149 SUPERFAMILY SSF55653 57 147 4.58E-25 T 28-03-2018 IPR020069 Ribosomal protein L9, C-terminal CO689_RS06960 38505c557e0693aaa53a279d28b3e6a4 149 Pfam PF01281 Ribosomal protein L9, N-terminal domain 1 47 6.5E-22 T 28-03-2018 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CO689_RS06960 38505c557e0693aaa53a279d28b3e6a4 149 Hamap MF_00503 50S ribosomal protein L9 [rplI]. 1 148 24.175 T 28-03-2018 IPR020594 Ribosomal protein L9, bacteria/chloroplast GO:0003735|GO:0005622|GO:0005840|GO:0006412 CO689_RS05035 fc16f5db614716747d357006b4a2d880 693 Pfam PF04464 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase 318 668 1.4E-32 T 28-03-2018 IPR007554 CDP-glycerol glycerophosphotransferase GO:0016020|GO:0047355 CO689_RS00985 0eaa3a7d43bbe43ba092c5d9b670d7b5 146 Gene3D G3DSA:3.90.20.10 22 144 2.8E-8 T 28-03-2018 CO689_RS00985 0eaa3a7d43bbe43ba092c5d9b670d7b5 146 SUPERFAMILY SSF58104 39 131 5.89E-5 T 28-03-2018 CO689_RS00985 0eaa3a7d43bbe43ba092c5d9b670d7b5 146 Pfam PF06103 Bacterial protein of unknown function (DUF948) 7 93 1.2E-28 T 28-03-2018 IPR009293 Uncharacterised protein family UPF0478 CO689_RS10330 62b1feda5effe6002c15dcbb429170b7 85 Pfam PF14166 YueH-like protein 12 75 2.6E-15 T 28-03-2018 IPR020260 Uncharacterised protein family YueH CO689_RS04280 6023991838b869e898d220ec73e8265a 204 Pfam PF09335 SNARE associated Golgi protein 30 160 3.5E-22 T 28-03-2018 IPR032816 SNARE associated Golgi protein CO689_RS03055 5d32d2304b6d2c31df410f30e8812bbf 146 Pfam PF00828 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A 28 144 9.8E-38 T 28-03-2018 IPR021131 Ribosomal protein L18e/L15P CO689_RS03055 5d32d2304b6d2c31df410f30e8812bbf 146 ProSitePatterns PS00475 Ribosomal protein L15 signature. 110 140 - T 28-03-2018 IPR001196 Ribosomal protein L15, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CO689_RS03055 5d32d2304b6d2c31df410f30e8812bbf 146 Gene3D G3DSA:3.100.10.10 39 146 3.3E-32 T 28-03-2018 CO689_RS03055 5d32d2304b6d2c31df410f30e8812bbf 146 SUPERFAMILY SSF52080 4 142 1.96E-48 T 28-03-2018 IPR021131 Ribosomal protein L18e/L15P CO689_RS03055 5d32d2304b6d2c31df410f30e8812bbf 146 TIGRFAM TIGR01071 rplO_bact: ribosomal protein uL15 2 142 1.6E-54 T 28-03-2018 IPR005749 Ribosomal protein L15, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CO689_RS03055 5d32d2304b6d2c31df410f30e8812bbf 146 Hamap MF_01341 50S ribosomal protein L15 [rplO]. 3 146 22.0 T 28-03-2018 IPR030878 Ribosomal protein L15 GO:0003735|GO:0006412|GO:0015934 CO689_RS06475 d1c06c1485286161c81ec6cd05c6ff17 303 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 248 261 - T 28-03-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 CO689_RS06475 d1c06c1485286161c81ec6cd05c6ff17 303 TIGRFAM TIGR02152 D_ribokin_bact: ribokinase 5 302 3.1E-108 T 28-03-2018 IPR011877 Ribokinase GO:0004747|GO:0006014 KEGG: 00030+2.7.1.15|Reactome: R-HSA-71336 CO689_RS06475 d1c06c1485286161c81ec6cd05c6ff17 303 SUPERFAMILY SSF53613 4 302 6.39E-82 T 28-03-2018 IPR029056 Ribokinase-like CO689_RS06475 d1c06c1485286161c81ec6cd05c6ff17 303 Gene3D G3DSA:3.40.1190.20 1 303 3.2E-77 T 28-03-2018 IPR029056 Ribokinase-like CO689_RS06475 d1c06c1485286161c81ec6cd05c6ff17 303 PRINTS PR00990 Ribokinase signature 7 28 2.6E-29 T 28-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 CO689_RS06475 d1c06c1485286161c81ec6cd05c6ff17 303 PRINTS PR00990 Ribokinase signature 175 190 2.6E-29 T 28-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 CO689_RS06475 d1c06c1485286161c81ec6cd05c6ff17 303 PRINTS PR00990 Ribokinase signature 35 54 2.6E-29 T 28-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 CO689_RS06475 d1c06c1485286161c81ec6cd05c6ff17 303 PRINTS PR00990 Ribokinase signature 107 120 2.6E-29 T 28-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 CO689_RS06475 d1c06c1485286161c81ec6cd05c6ff17 303 PRINTS PR00990 Ribokinase signature 219 230 2.6E-29 T 28-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 CO689_RS06475 d1c06c1485286161c81ec6cd05c6ff17 303 Hamap MF_01987 Ribokinase [rbsK]. 3 303 24.483 T 28-03-2018 IPR011877 Ribokinase GO:0004747|GO:0006014 KEGG: 00030+2.7.1.15|Reactome: R-HSA-71336 CO689_RS06475 d1c06c1485286161c81ec6cd05c6ff17 303 Pfam PF00294 pfkB family carbohydrate kinase 3 296 5.0E-67 T 28-03-2018 IPR011611 Carbohydrate kinase PfkB CO689_RS00615 41535068b34fdce1ed990288e5e15da6 172 Gene3D G3DSA:3.40.50.880 1 172 5.0E-40 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CO689_RS00615 41535068b34fdce1ed990288e5e15da6 172 TIGRFAM TIGR01382 PfpI: intracellular protease, PfpI family 4 170 5.5E-46 T 28-03-2018 IPR006286 Peptidase C56, PfpI CO689_RS00615 41535068b34fdce1ed990288e5e15da6 172 Pfam PF01965 DJ-1/PfpI family 3 169 7.7E-52 T 28-03-2018 IPR002818 DJ-1/PfpI CO689_RS00615 41535068b34fdce1ed990288e5e15da6 172 SUPERFAMILY SSF52317 1 170 7.74E-43 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CO689_RS02110 92ab7442124f3998135fde1bb4911b23 192 Hamap MF_00784 Accessory gene regulator protein B [agrB]. 4 188 19.003 T 28-03-2018 IPR006741 Accessory gene regulator B GO:0008233|GO:0009372|GO:0009405|GO:0016021 CO689_RS02110 92ab7442124f3998135fde1bb4911b23 192 Pfam PF04647 Accessory gene regulator B 10 175 5.3E-35 T 28-03-2018 IPR006741 Accessory gene regulator B GO:0008233|GO:0009372|GO:0009405|GO:0016021 CO689_RS02110 92ab7442124f3998135fde1bb4911b23 192 SMART SM00793 7 188 9.7E-73 T 28-03-2018 IPR006741 Accessory gene regulator B GO:0008233|GO:0009372|GO:0009405|GO:0016021 CO689_RS07490 507712c233b9a6232eb85850c6704fcc 475 Gene3D G3DSA:3.30.1360.60 5 82 1.9E-25 T 28-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 CO689_RS07490 507712c233b9a6232eb85850c6704fcc 475 TIGRFAM TIGR01992 PTS-IIBC-Tre: PTS system, trehalose-specific IIBC component 6 464 6.8E-198 T 28-03-2018 IPR011296 Phosphotransferase system, trehalose-specific IIBC component GO:0015574|GO:0015771|GO:0016021 KEGG: 00230+2.7.1.20|KEGG: 00500+2.7.1.201|MetaCyc: PWY-6619 CO689_RS07490 507712c233b9a6232eb85850c6704fcc 475 ProSitePatterns PS01035 PTS EIIB domains cysteine phosphorylation site signature. 20 37 - T 28-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 CO689_RS07490 507712c233b9a6232eb85850c6704fcc 475 Pfam PF00367 phosphotransferase system, EIIB 9 42 1.5E-15 T 28-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 CO689_RS07490 507712c233b9a6232eb85850c6704fcc 475 Pfam PF02378 Phosphotransferase system, EIIC 111 408 3.2E-43 T 28-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 CO689_RS07490 507712c233b9a6232eb85850c6704fcc 475 TIGRFAM TIGR00826 EIIB_glc: PTS system, glucose-like IIB component 29 110 9.1E-16 T 28-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 CO689_RS07490 507712c233b9a6232eb85850c6704fcc 475 SUPERFAMILY SSF55604 8 81 4.58E-20 T 28-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 CO689_RS07715 7dabcaf3052432b7147dc8c2029291fc 454 Pfam PF00483 Nucleotidyl transferase 5 217 4.1E-23 T 28-03-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 CO689_RS07715 7dabcaf3052432b7147dc8c2029291fc 454 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 402 430 - T 28-03-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 CO689_RS07715 7dabcaf3052432b7147dc8c2029291fc 454 Gene3D G3DSA:2.160.10.10 342 437 8.1E-19 T 28-03-2018 CO689_RS07715 7dabcaf3052432b7147dc8c2029291fc 454 Hamap MF_01631 Bifunctional protein GlmU [glmU]. 2 451 41.592 T 28-03-2018 IPR005882 Bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase GO:0000287|GO:0000902|GO:0003977|GO:0005737|GO:0009103|GO:0009252|GO:0019134 KEGG: 00520+2.3.1.157+2.7.7.23|KEGG: 00561+2.3.1.15|KEGG: 00564+2.3.1.15|MetaCyc: PWY-5514|MetaCyc: PWY-5667|MetaCyc: PWY-6453|MetaCyc: PWY-7411|MetaCyc: PWY-7587 CO689_RS07715 7dabcaf3052432b7147dc8c2029291fc 454 Gene3D G3DSA:3.90.550.10 1 239 1.8E-61 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CO689_RS07715 7dabcaf3052432b7147dc8c2029291fc 454 TIGRFAM TIGR01173 glmU: UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase 5 452 2.0E-179 T 28-03-2018 IPR005882 Bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase GO:0000287|GO:0000902|GO:0003977|GO:0005737|GO:0009103|GO:0009252|GO:0019134 KEGG: 00520+2.3.1.157+2.7.7.23|KEGG: 00561+2.3.1.15|KEGG: 00564+2.3.1.15|MetaCyc: PWY-5514|MetaCyc: PWY-5667|MetaCyc: PWY-6453|MetaCyc: PWY-7411|MetaCyc: PWY-7587 CO689_RS07715 7dabcaf3052432b7147dc8c2029291fc 454 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 254 282 0.0029 T 28-03-2018 IPR001451 Hexapeptide repeat CO689_RS07715 7dabcaf3052432b7147dc8c2029291fc 454 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 283 313 8.2E-4 T 28-03-2018 IPR001451 Hexapeptide repeat CO689_RS07715 7dabcaf3052432b7147dc8c2029291fc 454 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 316 350 2.2E-7 T 28-03-2018 IPR001451 Hexapeptide repeat CO689_RS07715 7dabcaf3052432b7147dc8c2029291fc 454 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 394 427 5.5E-8 T 28-03-2018 IPR001451 Hexapeptide repeat CO689_RS07715 7dabcaf3052432b7147dc8c2029291fc 454 SUPERFAMILY SSF53448 4 252 5.18E-66 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CO689_RS07715 7dabcaf3052432b7147dc8c2029291fc 454 Gene3D G3DSA:2.160.10.10 240 341 3.9E-28 T 28-03-2018 CO689_RS07715 7dabcaf3052432b7147dc8c2029291fc 454 SUPERFAMILY SSF51161 254 438 9.26E-47 T 28-03-2018 IPR011004 Trimeric LpxA-like CO689_RS03005 9c0b07fb7e564b1fce2725caf4d4564c 286 SUPERFAMILY SSF52540 3 238 4.71E-57 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CO689_RS03005 9c0b07fb7e564b1fce2725caf4d4564c 286 Gene3D G3DSA:3.40.50.300 1 275 3.7E-62 T 28-03-2018 CO689_RS03005 9c0b07fb7e564b1fce2725caf4d4564c 286 ProSitePatterns PS00211 ABC transporters family signature. 146 160 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CO689_RS03005 9c0b07fb7e564b1fce2725caf4d4564c 286 SMART SM00382 32 222 3.1E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain CO689_RS03005 9c0b07fb7e564b1fce2725caf4d4564c 286 Pfam PF00005 ABC transporter 23 174 4.2E-26 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CO689_RS03005 9c0b07fb7e564b1fce2725caf4d4564c 286 TIGRFAM TIGR04521 ECF_ATPase_2: energy-coupling factor transporter ATPase 3 276 2.0E-109 T 28-03-2018 IPR030946 Energy-coupling factor transporter ATP-binding protein EcfA2 CO689_RS03505 31aaad00393f9b7187122fe68c60173a 258 Gene3D G3DSA:1.10.530.10 98 247 3.1E-25 T 28-03-2018 CO689_RS03505 31aaad00393f9b7187122fe68c60173a 258 SMART SM00047 102 250 4.7E-33 T 28-03-2018 IPR002901 Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain GO:0004040 CO689_RS03505 31aaad00393f9b7187122fe68c60173a 258 Pfam PF01832 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase 115 242 1.6E-14 T 28-03-2018 IPR002901 Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain GO:0004040 CO689_RS13635 5505404e69595126558614f905b553d0 125 ProDom PD020942 TRANSPOSASE C TN554 TRANSPOSON TRANSPOSITION FOR DNA-BINDING TRANSPOSABLE DNA ELEMENT 7 122 4.0E-60 T 28-03-2018 CO689_RS12985 7711ebcb3ad6a1375cd9cc94fa475337 296 Gene3D G3DSA:3.40.50.10750 115 268 5.3E-32 T 28-03-2018 CO689_RS12985 7711ebcb3ad6a1375cd9cc94fa475337 296 Pfam PF01515 Phosphate acetyl/butaryl transferase 94 291 2.8E-28 T 28-03-2018 IPR002505 Phosphate acetyl/butaryl transferase GO:0008152|GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 CO689_RS12985 7711ebcb3ad6a1375cd9cc94fa475337 296 SUPERFAMILY SSF53659 11 293 3.89E-39 T 28-03-2018 CO689_RS12985 7711ebcb3ad6a1375cd9cc94fa475337 296 PIRSF PIRSF000428 1 296 5.4E-57 T 28-03-2018 IPR012147 Phosphate acetyl/butyryltransferase GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 CO689_RS06945 6f0d7c869cd5c0034e8e728a608b549b 297 Pfam PF10035 Uncharacterized protein conserved in bacteria (DUF2179) 234 288 6.1E-22 T 28-03-2018 IPR019264 Domain of unknown function DUF2179 CO689_RS06945 6f0d7c869cd5c0034e8e728a608b549b 297 PIRSF PIRSF006483 8 296 1.4E-96 T 28-03-2018 IPR003740 Uncharacterised membrane protein YitT CO689_RS06945 6f0d7c869cd5c0034e8e728a608b549b 297 Pfam PF02588 Uncharacterised 5xTM membrane BCR, YitT family COG1284 26 228 4.5E-65 T 28-03-2018 IPR003740 Uncharacterised membrane protein YitT CO689_RS03690 a6ba1220a21f1a9b91100f52267ad50f 68 SMART SM00530 4 59 1.7E-14 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CO689_RS03690 a6ba1220a21f1a9b91100f52267ad50f 68 SUPERFAMILY SSF47413 3 66 7.78E-18 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CO689_RS03690 a6ba1220a21f1a9b91100f52267ad50f 68 Gene3D G3DSA:1.10.260.40 1 68 1.1E-17 T 28-03-2018 CO689_RS03690 a6ba1220a21f1a9b91100f52267ad50f 68 Pfam PF01381 Helix-turn-helix 5 58 3.4E-16 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CO689_RS04290 392171f18d40c180c623c3952c9e1101 285 Pfam PF00005 ABC transporter 22 160 3.0E-26 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CO689_RS04290 392171f18d40c180c623c3952c9e1101 285 SMART SM00382 30 215 7.3E-15 T 28-03-2018 IPR003593 AAA+ ATPase domain CO689_RS04290 392171f18d40c180c623c3952c9e1101 285 Gene3D G3DSA:3.40.50.300 1 262 9.4E-49 T 28-03-2018 CO689_RS04290 392171f18d40c180c623c3952c9e1101 285 SUPERFAMILY SSF52540 3 225 1.94E-47 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CO689_RS12230 e0403292d3af49e3581d2049400b757a 98 Gene3D G3DSA:2.60.300.12 1 98 4.4E-11 T 28-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 CO689_RS12230 e0403292d3af49e3581d2049400b757a 98 SUPERFAMILY SSF89360 2 84 9.81E-10 T 28-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 CO689_RS12230 e0403292d3af49e3581d2049400b757a 98 Pfam PF01521 Iron-sulphur cluster biosynthesis 1 94 2.3E-6 T 28-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 CO689_RS02300 c1c92ed3ab0716e97f43dfc8f7d5b5e2 497 Gene3D G3DSA:1.20.1250.20 178 412 7.5E-4 T 28-03-2018 CO689_RS02300 c1c92ed3ab0716e97f43dfc8f7d5b5e2 497 Pfam PF03703 Bacterial PH domain 67 139 4.2E-11 T 28-03-2018 IPR005182 Domain of unknown function DUF304 CO689_RS02300 c1c92ed3ab0716e97f43dfc8f7d5b5e2 497 Pfam PF03703 Bacterial PH domain 258 345 2.9E-9 T 28-03-2018 IPR005182 Domain of unknown function DUF304 CO689_RS02300 c1c92ed3ab0716e97f43dfc8f7d5b5e2 497 PIRSF PIRSF026631 1 497 2.0E-95 T 28-03-2018 IPR014529 Uncharacterised conserved protein UCP026631 CO689_RS09240 a0aa68b6164cb4a9c6d0b7b619169feb 267 Pfam PF09250 Bifunctional DNA primase/polymerase, N-terminal 9 152 2.1E-7 T 28-03-2018 IPR015330 DNA primase/polymerase, bifunctional, N-terminal CO689_RS09240 a0aa68b6164cb4a9c6d0b7b619169feb 267 SUPERFAMILY SSF56747 5 156 2.35E-20 T 28-03-2018 CO689_RS09240 a0aa68b6164cb4a9c6d0b7b619169feb 267 SMART SM00943 7 156 9.2E-10 T 28-03-2018 IPR015330 DNA primase/polymerase, bifunctional, N-terminal CO689_RS06955 3ff0b72dd2a80c88e07208f6648cfb55 465 Gene3D G3DSA:1.10.860.10 3 151 1.1E-43 T 28-03-2018 IPR016136 DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal CO689_RS06955 3ff0b72dd2a80c88e07208f6648cfb55 465 SUPERFAMILY SSF48024 8 119 1.44E-34 T 28-03-2018 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 CO689_RS06955 3ff0b72dd2a80c88e07208f6648cfb55 465 Pfam PF03796 DnaB-like helicase C terminal domain 185 456 6.1E-115 T 28-03-2018 IPR007694 DNA helicase, DnaB-like, C-terminal GO:0003678|GO:0005524|GO:0006260 Reactome: R-HSA-2151201 CO689_RS06955 3ff0b72dd2a80c88e07208f6648cfb55 465 TIGRFAM TIGR00665 DnaB: replicative DNA helicase 10 457 4.8E-177 T 28-03-2018 IPR007692 DNA helicase, DnaB type GO:0003677|GO:0003678|GO:0005524|GO:0006260 CO689_RS06955 3ff0b72dd2a80c88e07208f6648cfb55 465 SUPERFAMILY SSF52540 183 449 1.03E-53 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CO689_RS06955 3ff0b72dd2a80c88e07208f6648cfb55 465 Pfam PF00772 DnaB-like helicase N terminal domain 10 110 1.7E-33 T 28-03-2018 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 CO689_RS06955 3ff0b72dd2a80c88e07208f6648cfb55 465 Gene3D G3DSA:3.40.50.300 167 465 9.1E-76 T 28-03-2018 CO689_RS07805 7812e71895113dfc08ff1e41231c33d6 331 ProSitePatterns PS01136 Uncharacterized protein family UPF0034 signature. 96 114 - T 28-03-2018 IPR018517 tRNA-dihydrouridine synthase, conserved site GO:0008033|GO:0017150|GO:0050660|GO:0055114 CO689_RS07805 7812e71895113dfc08ff1e41231c33d6 331 Gene3D G3DSA:1.10.1200.80 253 331 1.1E-22 T 28-03-2018 IPR024036 tRNA-dihydrouridine synthase, putative, C-terminal GO:0016491|GO:0055114 CO689_RS07805 7812e71895113dfc08ff1e41231c33d6 331 Gene3D G3DSA:3.20.20.70 7 250 1.1E-58 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CO689_RS07805 7812e71895113dfc08ff1e41231c33d6 331 Pfam PF01207 Dihydrouridine synthase (Dus) 14 321 1.2E-106 T 28-03-2018 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 CO689_RS07805 7812e71895113dfc08ff1e41231c33d6 331 SUPERFAMILY SSF51395 11 321 8.61E-93 T 28-03-2018 CO689_RS07805 7812e71895113dfc08ff1e41231c33d6 331 TIGRFAM TIGR00737 nifR3_yhdG: putative TIM-barrel protein, nifR3 family 4 322 2.7E-130 T 28-03-2018 IPR004652 tRNA-dihydrouridine synthase, TIM-barrel, NifR3 GO:0008033|GO:0016491|GO:0050660|GO:0055114 CO689_RS07805 7812e71895113dfc08ff1e41231c33d6 331 PIRSF PIRSF006621 1 331 1.1E-108 T 28-03-2018 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 CO689_RS09465 9908f5da98f55c79550ee98571207d59 98 Pfam PF00085 Thioredoxin 15 85 2.1E-7 T 28-03-2018 IPR013766 Thioredoxin domain GO:0045454 CO689_RS09465 9908f5da98f55c79550ee98571207d59 98 Gene3D G3DSA:3.40.30.10 11 95 7.3E-10 T 28-03-2018 CO689_RS09465 9908f5da98f55c79550ee98571207d59 98 SUPERFAMILY SSF52833 4 97 3.84E-15 T 28-03-2018 IPR012336 Thioredoxin-like fold CO689_RS03040 92dcb37964094cfb6429fb46337c2d55 72 SUPERFAMILY SSF50249 1 71 1.91E-29 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CO689_RS03040 92dcb37964094cfb6429fb46337c2d55 72 SMART SM00316 4 72 2.0E-7 T 28-03-2018 IPR022967 RNA-binding domain, S1 CO689_RS03040 92dcb37964094cfb6429fb46337c2d55 72 Gene3D G3DSA:2.40.50.140 1 72 2.3E-38 T 28-03-2018 CO689_RS03040 92dcb37964094cfb6429fb46337c2d55 72 Hamap MF_00075 Translation initiation factor IF-1 [infA]. 1 72 28.396 T 28-03-2018 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 CO689_RS03040 92dcb37964094cfb6429fb46337c2d55 72 TIGRFAM TIGR00008 infA: translation initiation factor IF-1 3 71 8.0E-40 T 28-03-2018 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 CO689_RS03040 92dcb37964094cfb6429fb46337c2d55 72 Pfam PF01176 Translation initiation factor 1A / IF-1 7 70 5.5E-29 T 28-03-2018 IPR006196 RNA-binding domain, S1, IF1 type GO:0003723|GO:0003743|GO:0006413 CO689_RS03475 261de6b32b681c0d3e430399e58c3dcd 356 Gene3D G3DSA:1.10.1040.10 196 351 2.9E-41 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CO689_RS03475 261de6b32b681c0d3e430399e58c3dcd 356 Pfam PF02317 NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain 187 333 3.7E-36 T 28-03-2018 IPR003421 Opine dehydrogenase GO:0016491|GO:0050662|GO:0055114 CO689_RS03475 261de6b32b681c0d3e430399e58c3dcd 356 Gene3D G3DSA:3.40.50.720 1 194 3.2E-16 T 28-03-2018 CO689_RS03475 261de6b32b681c0d3e430399e58c3dcd 356 SUPERFAMILY SSF48179 188 354 8.16E-39 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CO689_RS03475 261de6b32b681c0d3e430399e58c3dcd 356 SUPERFAMILY SSF51735 1 131 2.25E-15 T 28-03-2018 IPR016040 NAD(P)-binding domain CO689_RS03475 261de6b32b681c0d3e430399e58c3dcd 356 Pfam PF01210 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 2 103 6.4E-6 T 28-03-2018 IPR011128 Glycerol-3-phosphate dehydrogenase, NAD-dependent, N-terminal GO:0016616|GO:0046168|GO:0051287|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 CO689_RS07120 b5cb0e84fc4d49a61405f9dc1cafd3d1 1685 SMART SM01276 162 448 7.1E-7 T 28-03-2018 IPR031161 Peptidase family M60 domain CO689_RS07120 b5cb0e84fc4d49a61405f9dc1cafd3d1 1685 Pfam PF00746 LPXTG cell wall anchor motif 1641 1681 9.4E-6 T 28-03-2018 IPR019948 Gram-positive LPXTG cell wall anchor CO689_RS07120 b5cb0e84fc4d49a61405f9dc1cafd3d1 1685 Gene3D G3DSA:2.60.40.1310 1093 1176 2.9E-10 T 28-03-2018 CO689_RS07120 b5cb0e84fc4d49a61405f9dc1cafd3d1 1685 Gene3D G3DSA:2.60.40.1310 1274 1386 1.6E-11 T 28-03-2018 CO689_RS07120 b5cb0e84fc4d49a61405f9dc1cafd3d1 1685 Gene3D G3DSA:2.60.40.1310 1177 1273 1.2E-13 T 28-03-2018 CO689_RS07120 b5cb0e84fc4d49a61405f9dc1cafd3d1 1685 Gene3D G3DSA:2.60.40.1310 848 945 4.8E-8 T 28-03-2018 CO689_RS07120 b5cb0e84fc4d49a61405f9dc1cafd3d1 1685 Gene3D G3DSA:2.60.40.1310 1019 1092 2.9E-10 T 28-03-2018 CO689_RS07120 b5cb0e84fc4d49a61405f9dc1cafd3d1 1685 Gene3D G3DSA:2.60.40.1310 946 1018 1.9E-7 T 28-03-2018 CO689_RS07120 b5cb0e84fc4d49a61405f9dc1cafd3d1 1685 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 1648 1680 4.2E-4 T 28-03-2018 CO689_RS07120 b5cb0e84fc4d49a61405f9dc1cafd3d1 1685 Pfam PF03272 Putative mucin or carbohydrate-binding module 675 794 3.2E-23 T 28-03-2018 IPR004954 Putative mucin or carbohydrate-binding domain GO:0016032 CO689_RS11215 4043a79cfa7c0bcba8629476de25f381 717 Gene3D G3DSA:3.40.710.10 240 590 9.3E-73 T 28-03-2018 CO689_RS11215 4043a79cfa7c0bcba8629476de25f381 717 SUPERFAMILY SSF54184 658 712 3.4E-12 T 28-03-2018 CO689_RS11215 4043a79cfa7c0bcba8629476de25f381 717 SUPERFAMILY SSF56519 60 242 8.24E-45 T 28-03-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 CO689_RS11215 4043a79cfa7c0bcba8629476de25f381 717 Pfam PF00905 Penicillin binding protein transpeptidase domain 269 578 2.7E-81 T 28-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 CO689_RS11215 4043a79cfa7c0bcba8629476de25f381 717 Pfam PF03717 Penicillin-binding Protein dimerisation domain 61 224 8.5E-24 T 28-03-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 CO689_RS11215 4043a79cfa7c0bcba8629476de25f381 717 Gene3D G3DSA:3.90.1310.10 27 239 9.4E-38 T 28-03-2018 CO689_RS11215 4043a79cfa7c0bcba8629476de25f381 717 SUPERFAMILY SSF54184 598 655 9.94E-14 T 28-03-2018 CO689_RS11215 4043a79cfa7c0bcba8629476de25f381 717 SUPERFAMILY SSF56601 195 607 2.07E-78 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CO689_RS11215 4043a79cfa7c0bcba8629476de25f381 717 Pfam PF03793 PASTA domain 658 712 1.8E-6 T 28-03-2018 IPR005543 PASTA domain CO689_RS11215 4043a79cfa7c0bcba8629476de25f381 717 Pfam PF03793 PASTA domain 601 651 1.3E-6 T 28-03-2018 IPR005543 PASTA domain CO689_RS11215 4043a79cfa7c0bcba8629476de25f381 717 SMART SM00740 657 713 0.032 T 28-03-2018 IPR005543 PASTA domain CO689_RS11215 4043a79cfa7c0bcba8629476de25f381 717 SMART SM00740 596 656 3.2E-8 T 28-03-2018 IPR005543 PASTA domain CO689_RS02175 21b288166b5094586c72f6e15ce65f81 157 Pfam PF02367 Threonylcarbamoyl adenosine biosynthesis protein TsaE 5 129 8.1E-36 T 28-03-2018 IPR003442 tRNA threonylcarbamoyl adenosine modification protein TsaE GO:0002949 CO689_RS02175 21b288166b5094586c72f6e15ce65f81 157 Gene3D G3DSA:3.40.50.300 1 148 3.0E-47 T 28-03-2018 CO689_RS02175 21b288166b5094586c72f6e15ce65f81 157 SUPERFAMILY SSF52540 17 126 1.18E-19 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CO689_RS02175 21b288166b5094586c72f6e15ce65f81 157 TIGRFAM TIGR00150 T6A_YjeE: tRNA threonylcarbamoyl adenosine modification protein YjeE 7 135 7.5E-38 T 28-03-2018 IPR003442 tRNA threonylcarbamoyl adenosine modification protein TsaE GO:0002949 CO689_RS02940 6378e86a3aff06f6edfc0e5eb9d6ec0b 644 SUPERFAMILY SSF56784 310 329 3.2E-50 T 28-03-2018 IPR023214 HAD-like domain CO689_RS02940 6378e86a3aff06f6edfc0e5eb9d6ec0b 644 SUPERFAMILY SSF56784 368 612 3.2E-50 T 28-03-2018 IPR023214 HAD-like domain CO689_RS02940 6378e86a3aff06f6edfc0e5eb9d6ec0b 644 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 313 319 - T 28-03-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 CO689_RS02940 6378e86a3aff06f6edfc0e5eb9d6ec0b 644 SUPERFAMILY SSF81665 220 305 3.79E-16 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CO689_RS02940 6378e86a3aff06f6edfc0e5eb9d6ec0b 644 SUPERFAMILY SSF81665 70 122 3.79E-16 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CO689_RS02940 6378e86a3aff06f6edfc0e5eb9d6ec0b 644 SUPERFAMILY SSF81665 561 589 3.79E-16 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CO689_RS02940 6378e86a3aff06f6edfc0e5eb9d6ec0b 644 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 68 614 2.3E-171 T 28-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 CO689_RS02940 6378e86a3aff06f6edfc0e5eb9d6ec0b 644 SUPERFAMILY SSF81653 129 219 1.96E-22 T 28-03-2018 IPR008250 P-type ATPase, A domain Reactome: R-HSA-936837 CO689_RS02940 6378e86a3aff06f6edfc0e5eb9d6ec0b 644 Pfam PF00122 E1-E2 ATPase 119 291 1.3E-43 T 28-03-2018 CO689_RS02940 6378e86a3aff06f6edfc0e5eb9d6ec0b 644 Gene3D G3DSA:3.40.1110.10 328 435 1.3E-24 T 28-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 CO689_RS02940 6378e86a3aff06f6edfc0e5eb9d6ec0b 644 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 543 568 4.8E-7 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CO689_RS02940 6378e86a3aff06f6edfc0e5eb9d6ec0b 644 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 511 527 4.8E-7 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CO689_RS02940 6378e86a3aff06f6edfc0e5eb9d6ec0b 644 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 483 499 4.8E-7 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CO689_RS02940 6378e86a3aff06f6edfc0e5eb9d6ec0b 644 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 91 592 1.2E-73 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CO689_RS02940 6378e86a3aff06f6edfc0e5eb9d6ec0b 644 Gene3D G3DSA:1.20.1110.10 10 327 8.9E-34 T 28-03-2018 CO689_RS02940 6378e86a3aff06f6edfc0e5eb9d6ec0b 644 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 56 614 4.5E-122 T 28-03-2018 CO689_RS02940 6378e86a3aff06f6edfc0e5eb9d6ec0b 644 Pfam PF00702 haloacid dehalogenase-like hydrolase 307 525 1.9E-38 T 28-03-2018 CO689_RS02940 6378e86a3aff06f6edfc0e5eb9d6ec0b 644 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 458 468 9.4E-25 T 28-03-2018 CO689_RS02940 6378e86a3aff06f6edfc0e5eb9d6ec0b 644 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 169 183 9.4E-25 T 28-03-2018 CO689_RS02940 6378e86a3aff06f6edfc0e5eb9d6ec0b 644 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 511 530 9.4E-25 T 28-03-2018 CO689_RS02940 6378e86a3aff06f6edfc0e5eb9d6ec0b 644 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 435 446 9.4E-25 T 28-03-2018 CO689_RS02940 6378e86a3aff06f6edfc0e5eb9d6ec0b 644 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 311 325 9.4E-25 T 28-03-2018 CO689_RS02940 6378e86a3aff06f6edfc0e5eb9d6ec0b 644 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 535 547 9.4E-25 T 28-03-2018 CO689_RS02940 6378e86a3aff06f6edfc0e5eb9d6ec0b 644 Gene3D G3DSA:3.40.50.1000 436 577 1.2E-39 T 28-03-2018 IPR023214 HAD-like domain CO689_RS11070 fcccbe672f631534f87e84531b1ddae2 173 Pfam PF02674 Colicin V production protein 4 163 1.6E-25 T 28-03-2018 IPR003825 Colicin V production, CvpA GO:0009403|GO:0016020 CO689_RS09185 a3c593e86232afd767512ae17dd66844 437 TIGRFAM TIGR00796 livcs: branched-chain amino acid transport system II carrier protein 9 411 2.9E-117 T 28-03-2018 IPR004685 Branched-chain amino acid transport system II carrier protein GO:0015658|GO:0015803|GO:0016021 CO689_RS09185 a3c593e86232afd767512ae17dd66844 437 Pfam PF05525 Branched-chain amino acid transport protein 2 423 1.2E-127 T 28-03-2018 IPR004685 Branched-chain amino acid transport system II carrier protein GO:0015658|GO:0015803|GO:0016021 CO689_RS11675 f6730d8404dc17c2baf83929461a85fb 260 Gene3D G3DSA:3.40.50.10490 5 259 4.6E-106 T 28-03-2018 CO689_RS11675 f6730d8404dc17c2baf83929461a85fb 260 ProSitePatterns PS00963 Ribosomal protein S2 signature 2. 158 182 - T 28-03-2018 IPR018130 Ribosomal protein S2, conserved site GO:0003735|GO:0005840|GO:0006412 CO689_RS11675 f6730d8404dc17c2baf83929461a85fb 260 TIGRFAM TIGR01011 rpsB_bact: ribosomal protein uS2 3 226 3.1E-110 T 28-03-2018 IPR005706 Ribosomal protein S2, bacteria/mitochondria/plastid GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CO689_RS11675 f6730d8404dc17c2baf83929461a85fb 260 Hamap MF_00291_B 30S ribosomal protein S2 [rpsB]. 2 225 43.308 T 28-03-2018 IPR005706 Ribosomal protein S2, bacteria/mitochondria/plastid GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CO689_RS11675 f6730d8404dc17c2baf83929461a85fb 260 ProSitePatterns PS00962 Ribosomal protein S2 signature 1. 6 17 - T 28-03-2018 IPR018130 Ribosomal protein S2, conserved site GO:0003735|GO:0005840|GO:0006412 CO689_RS11675 f6730d8404dc17c2baf83929461a85fb 260 SUPERFAMILY SSF52313 6 231 1.12E-98 T 28-03-2018 IPR023591 Ribosomal protein S2, flavodoxin-like domain CO689_RS11675 f6730d8404dc17c2baf83929461a85fb 260 Pfam PF00318 Ribosomal protein S2 9 224 1.2E-100 T 28-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CO689_RS11675 f6730d8404dc17c2baf83929461a85fb 260 PRINTS PR00395 Ribosomal protein S2 signature 196 210 1.1E-40 T 28-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CO689_RS11675 f6730d8404dc17c2baf83929461a85fb 260 PRINTS PR00395 Ribosomal protein S2 signature 6 24 1.1E-40 T 28-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CO689_RS11675 f6730d8404dc17c2baf83929461a85fb 260 PRINTS PR00395 Ribosomal protein S2 signature 158 175 1.1E-40 T 28-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CO689_RS11675 f6730d8404dc17c2baf83929461a85fb 260 PRINTS PR00395 Ribosomal protein S2 signature 87 104 1.1E-40 T 28-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CO689_RS11675 f6730d8404dc17c2baf83929461a85fb 260 PRINTS PR00395 Ribosomal protein S2 signature 37 46 1.1E-40 T 28-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CO689_RS11675 f6730d8404dc17c2baf83929461a85fb 260 PRINTS PR00395 Ribosomal protein S2 signature 175 186 1.1E-40 T 28-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CO689_RS05490 e13af5ddadf41fc5cffc41bc9b11986c 262 Gene3D G3DSA:3.40.1640.10 1 166 1.8E-67 T 28-03-2018 CO689_RS05490 e13af5ddadf41fc5cffc41bc9b11986c 262 Gene3D G3DSA:3.40.1640.10 200 262 8.7E-11 T 28-03-2018 CO689_RS05490 e13af5ddadf41fc5cffc41bc9b11986c 262 SUPERFAMILY SSF160920 4 256 1.44E-110 T 28-03-2018 CO689_RS05490 e13af5ddadf41fc5cffc41bc9b11986c 262 Pfam PF07286 Protein of unknown function (DUF1445) 112 254 3.5E-64 T 28-03-2018 IPR009906 D-glutamate cyclase CO689_RS05490 e13af5ddadf41fc5cffc41bc9b11986c 262 Hamap MF_01830 UPF0317 protein . 8 262 51.023 T 28-03-2018 IPR016938 Uncharacterised protein family UPF0317 CO689_RS05490 e13af5ddadf41fc5cffc41bc9b11986c 262 PIRSF PIRSF029755 1 262 2.0E-116 T 28-03-2018 IPR016938 Uncharacterised protein family UPF0317 CO689_RS08205 9ab372a825ec9b8b7c20aa3a2b357439 270 Gene3D G3DSA:1.10.3720.10 19 270 3.2E-29 T 28-03-2018 CO689_RS08205 9ab372a825ec9b8b7c20aa3a2b357439 270 TIGRFAM TIGR01097 PhnE: phosphonate ABC transporter, permease protein PhnE 18 269 2.9E-80 T 28-03-2018 IPR005769 ABC transporter, permease PhnE/PtxC GO:0005887|GO:0015604|GO:0015716 CO689_RS08205 9ab372a825ec9b8b7c20aa3a2b357439 270 SUPERFAMILY SSF161098 74 262 1.57E-33 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CO689_RS08205 9ab372a825ec9b8b7c20aa3a2b357439 270 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 98 255 2.4E-11 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CO689_RS05040 3a5467ce02180e6e174b71852a09971c 368 Pfam PF00535 Glycosyl transferase family 2 3 148 3.1E-30 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CO689_RS05040 3a5467ce02180e6e174b71852a09971c 368 SUPERFAMILY SSF53448 1 213 1.22E-47 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CO689_RS05040 3a5467ce02180e6e174b71852a09971c 368 Gene3D G3DSA:3.90.550.10 1 365 1.6E-45 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CO689_RS08890 112d0ecfc88048a7f7c24a5660d74b12 141 PIRSF PIRSF006113 14 136 3.8E-22 T 28-03-2018 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family protein Reactome: R-HSA-1474151 CO689_RS08890 112d0ecfc88048a7f7c24a5660d74b12 141 SUPERFAMILY SSF55620 14 135 3.34E-32 T 28-03-2018 CO689_RS08890 112d0ecfc88048a7f7c24a5660d74b12 141 TIGRFAM TIGR03367 queuosine_QueD: queuosine biosynthesis protein QueD 16 103 1.0E-26 T 28-03-2018 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family protein Reactome: R-HSA-1474151 CO689_RS08890 112d0ecfc88048a7f7c24a5660d74b12 141 Gene3D G3DSA:3.30.479.10 3 137 1.6E-32 T 28-03-2018 CO689_RS08890 112d0ecfc88048a7f7c24a5660d74b12 141 Pfam PF01242 6-pyruvoyl tetrahydropterin synthase 17 134 6.6E-30 T 28-03-2018 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family protein Reactome: R-HSA-1474151 CO689_RS07590 21ba5cac75bd83a493721024ffe3371b 242 Pfam PF05175 Methyltransferase small domain 30 171 6.4E-15 T 28-03-2018 IPR007848 Methyltransferase small domain GO:0008168 CO689_RS07590 21ba5cac75bd83a493721024ffe3371b 242 SUPERFAMILY SSF53335 11 203 1.12E-27 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CO689_RS07590 21ba5cac75bd83a493721024ffe3371b 242 Gene3D G3DSA:3.40.50.150 6 242 7.5E-37 T 28-03-2018 CO689_RS02935 1d6776d1d81d2b6c60a6f92458d044b4 213 Pfam PF00027 Cyclic nucleotide-binding domain 33 119 2.4E-18 T 28-03-2018 IPR000595 Cyclic nucleotide-binding domain CO689_RS02935 1d6776d1d81d2b6c60a6f92458d044b4 213 SMART SM00100 13 132 4.0E-22 T 28-03-2018 IPR000595 Cyclic nucleotide-binding domain CO689_RS02935 1d6776d1d81d2b6c60a6f92458d044b4 213 SUPERFAMILY SSF51206 8 146 8.51E-34 T 28-03-2018 IPR018490 Cyclic nucleotide-binding-like CO689_RS02935 1d6776d1d81d2b6c60a6f92458d044b4 213 Pfam PF13545 Crp-like helix-turn-helix domain 152 205 3.9E-10 T 28-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 CO689_RS02935 1d6776d1d81d2b6c60a6f92458d044b4 213 Gene3D G3DSA:1.10.10.10 135 213 3.0E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS02935 1d6776d1d81d2b6c60a6f92458d044b4 213 SUPERFAMILY SSF46785 157 207 1.17E-7 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS02935 1d6776d1d81d2b6c60a6f92458d044b4 213 SMART SM00419 163 212 2.2E-6 T 28-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 CO689_RS02935 1d6776d1d81d2b6c60a6f92458d044b4 213 Gene3D G3DSA:2.60.120.10 6 134 4.0E-29 T 28-03-2018 IPR014710 RmlC-like jelly roll fold CO689_RS09170 e46890f455bfd32959307797267d7a13 332 TIGRFAM TIGR01826 CofD_related: conserved hypothetical protein 6 315 6.7E-124 T 28-03-2018 IPR010119 Gluconeogenesis factor CO689_RS09170 e46890f455bfd32959307797267d7a13 332 Hamap MF_00973 Gluconeogenesis factor. 2 318 33.671 T 28-03-2018 IPR010119 Gluconeogenesis factor CO689_RS09170 e46890f455bfd32959307797267d7a13 332 SUPERFAMILY SSF142338 3 313 4.71E-99 T 28-03-2018 CO689_RS09170 e46890f455bfd32959307797267d7a13 332 Gene3D G3DSA:3.40.50.10680 83 324 3.2E-61 T 28-03-2018 CO689_RS09170 e46890f455bfd32959307797267d7a13 332 Pfam PF01933 Uncharacterised protein family UPF0052 6 289 5.1E-107 T 28-03-2018 IPR002882 LPPG:FO 2-phospho-L-lactate transferase CofD/UPF0052 CO689_RS12835 489b95220fb070e972068a0b93765efe 519 Pfam PF01476 LysM domain 472 518 2.1E-5 T 28-03-2018 IPR018392 LysM domain CO689_RS12835 489b95220fb070e972068a0b93765efe 519 SMART SM00257 470 518 8.9E-4 T 28-03-2018 IPR018392 LysM domain CO689_RS12835 489b95220fb070e972068a0b93765efe 519 Gene3D G3DSA:3.10.350.10 467 519 2.5E-9 T 28-03-2018 CO689_RS12835 489b95220fb070e972068a0b93765efe 519 SUPERFAMILY SSF54106 469 518 1.31E-5 T 28-03-2018 IPR018392 LysM domain CO689_RS12750 58330cf22d4fc5278a42999911755531 204 Pfam PF07187 Protein of unknown function (DUF1405) 27 184 4.0E-54 T 28-03-2018 IPR009845 Protein of unknown function DUF1405 CO689_RS03210 9af04ce283299ec4208e16ce7ca22774 389 Gene3D G3DSA:2.30.40.10 1 66 1.4E-10 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CO689_RS03210 9af04ce283299ec4208e16ce7ca22774 389 Gene3D G3DSA:3.20.20.140 67 349 2.2E-48 T 28-03-2018 CO689_RS03210 9af04ce283299ec4208e16ce7ca22774 389 Pfam PF01979 Amidohydrolase family 49 381 2.0E-49 T 28-03-2018 IPR006680 Amidohydrolase-related GO:0016787 CO689_RS03210 9af04ce283299ec4208e16ce7ca22774 389 SUPERFAMILY SSF51338 350 382 2.62E-10 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CO689_RS03210 9af04ce283299ec4208e16ce7ca22774 389 SUPERFAMILY SSF51338 34 53 2.62E-10 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CO689_RS03210 9af04ce283299ec4208e16ce7ca22774 389 SUPERFAMILY SSF51556 53 350 7.23E-81 T 28-03-2018 IPR032466 Metal-dependent hydrolase CO689_RS03180 546400e29dcf6de982f5eec4e1f3047e 287 Gene3D G3DSA:3.40.630.30 89 287 4.2E-11 T 28-03-2018 CO689_RS03180 546400e29dcf6de982f5eec4e1f3047e 287 Pfam PF00583 Acetyltransferase (GNAT) family 177 274 2.0E-7 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CO689_RS03180 546400e29dcf6de982f5eec4e1f3047e 287 SUPERFAMILY SSF55729 167 281 1.36E-11 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CO689_RS02925 525ba32cea31b426d556ba15e5467a17 271 Hamap MF_00921 Putative pyruvate, phosphate dikinase regulatory protein. 8 271 54.316 T 28-03-2018 IPR026565 Putative pyruvate, phosphate dikinase regulatory protein CO689_RS02925 525ba32cea31b426d556ba15e5467a17 271 Gene3D G3DSA:3.40.50.300 39 271 1.9E-4 T 28-03-2018 CO689_RS02925 525ba32cea31b426d556ba15e5467a17 271 Pfam PF03618 Kinase/pyrophosphorylase 10 265 3.7E-85 T 28-03-2018 IPR005177 Bifunctional kinase-pyrophosphorylase GO:0005524|GO:0016772 CO689_RS12485 a713e09aa7155f9d1da352bad1a497f8 690 Pfam PF17210 SdrD B-like domain 328 431 2.4E-24 T 28-03-2018 IPR033764 SD-repeat containing protein, B domain CO689_RS12485 a713e09aa7155f9d1da352bad1a497f8 690 Pfam PF17210 SdrD B-like domain 443 534 2.1E-26 T 28-03-2018 IPR033764 SD-repeat containing protein, B domain CO689_RS12485 a713e09aa7155f9d1da352bad1a497f8 690 Pfam PF17210 SdrD B-like domain 103 191 8.2E-25 T 28-03-2018 IPR033764 SD-repeat containing protein, B domain CO689_RS12485 a713e09aa7155f9d1da352bad1a497f8 690 Pfam PF17210 SdrD B-like domain 218 309 3.4E-26 T 28-03-2018 IPR033764 SD-repeat containing protein, B domain CO689_RS12485 a713e09aa7155f9d1da352bad1a497f8 690 SUPERFAMILY SSF117074 316 400 3.4E-21 T 28-03-2018 CO689_RS12485 a713e09aa7155f9d1da352bad1a497f8 690 SUPERFAMILY SSF117074 213 290 1.19E-19 T 28-03-2018 CO689_RS12485 a713e09aa7155f9d1da352bad1a497f8 690 SUPERFAMILY SSF117074 93 180 3.79E-18 T 28-03-2018 CO689_RS12485 a713e09aa7155f9d1da352bad1a497f8 690 SUPERFAMILY SSF117074 425 515 3.79E-21 T 28-03-2018 CO689_RS12485 a713e09aa7155f9d1da352bad1a497f8 690 Pfam PF04650 YSIRK type signal peptide 9 31 1.9E-9 T 28-03-2018 IPR005877 YSIRK Gram-positive signal peptide GO:0016020 CO689_RS12485 a713e09aa7155f9d1da352bad1a497f8 690 Gene3D G3DSA:2.60.40.10 98 215 1.4E-22 T 28-03-2018 IPR013783 Immunoglobulin-like fold CO689_RS12485 a713e09aa7155f9d1da352bad1a497f8 690 Gene3D G3DSA:2.60.40.10 326 435 2.3E-22 T 28-03-2018 IPR013783 Immunoglobulin-like fold CO689_RS12485 a713e09aa7155f9d1da352bad1a497f8 690 Gene3D G3DSA:2.60.40.10 438 577 5.7E-22 T 28-03-2018 IPR013783 Immunoglobulin-like fold CO689_RS12485 a713e09aa7155f9d1da352bad1a497f8 690 Gene3D G3DSA:2.60.40.10 216 325 1.3E-20 T 28-03-2018 IPR013783 Immunoglobulin-like fold CO689_RS12485 a713e09aa7155f9d1da352bad1a497f8 690 TIGRFAM TIGR01168 YSIRK_signal: gram-positive signal peptide, YSIRK family 1 41 1.0E-10 T 28-03-2018 IPR005877 YSIRK Gram-positive signal peptide GO:0016020 CO689_RS12325 677cd3832e690e0f330175e40e0306f4 469 Pfam PF04715 Anthranilate synthase component I, N terminal region 14 150 8.0E-24 T 28-03-2018 IPR006805 Anthranilate synthase component I, N-terminal GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CO689_RS12325 677cd3832e690e0f330175e40e0306f4 469 PRINTS PR00095 Anthranilate synthase component I signature 308 321 8.7E-19 T 28-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CO689_RS12325 677cd3832e690e0f330175e40e0306f4 469 PRINTS PR00095 Anthranilate synthase component I signature 402 416 8.7E-19 T 28-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CO689_RS12325 677cd3832e690e0f330175e40e0306f4 469 PRINTS PR00095 Anthranilate synthase component I signature 417 431 8.7E-19 T 28-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CO689_RS12325 677cd3832e690e0f330175e40e0306f4 469 PRINTS PR00095 Anthranilate synthase component I signature 322 335 8.7E-19 T 28-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CO689_RS12325 677cd3832e690e0f330175e40e0306f4 469 Gene3D G3DSA:3.60.120.10 3 468 7.2E-136 T 28-03-2018 IPR005801 ADC synthase GO:0009058 CO689_RS12325 677cd3832e690e0f330175e40e0306f4 469 SUPERFAMILY SSF56322 15 467 1.14E-129 T 28-03-2018 IPR005801 ADC synthase GO:0009058 CO689_RS12325 677cd3832e690e0f330175e40e0306f4 469 Pfam PF00425 chorismate binding enzyme 201 460 1.8E-87 T 28-03-2018 IPR015890 Chorismate-utilising enzyme, C-terminal CO689_RS03145 850c84602697126f4c085d30f34eaf70 207 Gene3D G3DSA:3.40.1370.10 2 146 2.0E-56 T 28-03-2018 IPR023574 Ribosomal protein L4 domain GO:0003735|GO:0005840|GO:0006412 CO689_RS03145 850c84602697126f4c085d30f34eaf70 207 Gene3D G3DSA:3.40.1370.10 147 205 1.2E-14 T 28-03-2018 IPR023574 Ribosomal protein L4 domain GO:0003735|GO:0005840|GO:0006412 CO689_RS03145 850c84602697126f4c085d30f34eaf70 207 Hamap MF_01328_B 50S ribosomal protein L4 [rplD]. 9 207 36.751 T 28-03-2018 IPR013005 50S ribosomal protein uL4 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CO689_RS03145 850c84602697126f4c085d30f34eaf70 207 TIGRFAM TIGR03953 rplD_bact: 50S ribosomal protein uL4 17 204 2.7E-81 T 28-03-2018 IPR013005 50S ribosomal protein uL4 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CO689_RS03145 850c84602697126f4c085d30f34eaf70 207 SUPERFAMILY SSF52166 1 206 2.62E-81 T 28-03-2018 IPR023574 Ribosomal protein L4 domain GO:0003735|GO:0005840|GO:0006412 CO689_RS03145 850c84602697126f4c085d30f34eaf70 207 Pfam PF00573 Ribosomal protein L4/L1 family 17 204 1.8E-71 T 28-03-2018 IPR002136 Ribosomal protein L4/L1e GO:0003735|GO:0005840|GO:0006412 CO689_RS02070 2461b3592860b805dd072546ca600f96 72 Pfam PF01381 Helix-turn-helix 16 64 3.6E-11 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CO689_RS02070 2461b3592860b805dd072546ca600f96 72 SUPERFAMILY SSF47413 7 68 1.59E-14 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CO689_RS02070 2461b3592860b805dd072546ca600f96 72 Gene3D G3DSA:1.10.260.40 2 72 1.2E-14 T 28-03-2018 CO689_RS02070 2461b3592860b805dd072546ca600f96 72 SMART SM00530 9 64 6.1E-10 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CO689_RS08130 7f0d6df7faa740c10f5fd07a727495a4 131 PIRSF PIRSF016789 1 122 3.5E-40 T 28-03-2018 IPR007401 Protein of unknown function DUF454 CO689_RS08130 7f0d6df7faa740c10f5fd07a727495a4 131 Pfam PF04304 Protein of unknown function (DUF454) 2 114 1.7E-37 T 28-03-2018 IPR007401 Protein of unknown function DUF454 CO689_RS10700 4eb5249fb07fa2c7ad83ac1371ad89f5 382 Pfam PF00042 Globin 8 102 1.3E-8 T 28-03-2018 IPR000971 Globin GO:0020037 CO689_RS10700 4eb5249fb07fa2c7ad83ac1371ad89f5 382 PRINTS PR00410 Phenol hydroxylase reductase family signature 246 255 2.1E-7 T 28-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 CO689_RS10700 4eb5249fb07fa2c7ad83ac1371ad89f5 382 PRINTS PR00410 Phenol hydroxylase reductase family signature 179 191 2.1E-7 T 28-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 CO689_RS10700 4eb5249fb07fa2c7ad83ac1371ad89f5 382 PRINTS PR00410 Phenol hydroxylase reductase family signature 261 280 2.1E-7 T 28-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 CO689_RS10700 4eb5249fb07fa2c7ad83ac1371ad89f5 382 SUPERFAMILY SSF63380 146 253 7.35E-20 T 28-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 CO689_RS10700 4eb5249fb07fa2c7ad83ac1371ad89f5 382 SUPERFAMILY SSF52343 255 376 2.62E-24 T 28-03-2018 CO689_RS10700 4eb5249fb07fa2c7ad83ac1371ad89f5 382 Pfam PF00970 Oxidoreductase FAD-binding domain 152 251 7.6E-9 T 28-03-2018 IPR008333 Oxidoreductase, FAD-binding domain Reactome: R-HSA-1237044 CO689_RS10700 4eb5249fb07fa2c7ad83ac1371ad89f5 382 Gene3D G3DSA:3.40.50.80 254 381 6.8E-19 T 28-03-2018 CO689_RS10700 4eb5249fb07fa2c7ad83ac1371ad89f5 382 Gene3D G3DSA:1.10.490.10 1 157 2.4E-30 T 28-03-2018 CO689_RS10700 4eb5249fb07fa2c7ad83ac1371ad89f5 382 Gene3D G3DSA:2.40.30.10 158 253 2.3E-19 T 28-03-2018 CO689_RS10700 4eb5249fb07fa2c7ad83ac1371ad89f5 382 Pfam PF00175 Oxidoreductase NAD-binding domain 262 354 2.3E-4 T 28-03-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 CO689_RS10700 4eb5249fb07fa2c7ad83ac1371ad89f5 382 SUPERFAMILY SSF46458 1 149 3.16E-36 T 28-03-2018 IPR009050 Globin-like CO689_RS07485 39b0bc52ce5bdbb1b80f30fd0bff0745 129 Gene3D G3DSA:3.10.180.10 1 129 5.8E-24 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CO689_RS07485 39b0bc52ce5bdbb1b80f30fd0bff0745 129 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 7 125 1.7E-16 T 28-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CO689_RS07485 39b0bc52ce5bdbb1b80f30fd0bff0745 129 SUPERFAMILY SSF54593 7 128 1.88E-24 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CO689_RS03875 3fd35c4532a692e3ffdc16405eb0a1ec 112 Pfam PF16230 Domain of unknown function (DUF4889) 40 110 1.8E-34 T 28-03-2018 IPR032613 Protein of unknown function DUF4889 CO689_RS03960 5f6ed20004167937f198cdf63e3b3e8a 522 Gene3D G3DSA:3.30.70.20 5 198 6.3E-29 T 28-03-2018 CO689_RS03960 5f6ed20004167937f198cdf63e3b3e8a 522 TIGRFAM TIGR01660 narH: nitrate reductase, beta subunit 1 490 5.8E-253 T 28-03-2018 IPR006547 Nitrate reductase, beta subunit GO:0008940|GO:0009325|GO:0042126|GO:0055114 KEGG: 00910+1.7.99.4 CO689_RS03960 5f6ed20004167937f198cdf63e3b3e8a 522 Gene3D G3DSA:3.30.70.20 237 363 1.0E-26 T 28-03-2018 CO689_RS03960 5f6ed20004167937f198cdf63e3b3e8a 522 Gene3D G3DSA:3.30.70.20 199 236 5.6E-18 T 28-03-2018 CO689_RS03960 5f6ed20004167937f198cdf63e3b3e8a 522 Gene3D G3DSA:1.10.3650.10 364 437 7.8E-27 T 28-03-2018 CO689_RS03960 5f6ed20004167937f198cdf63e3b3e8a 522 SUPERFAMILY SSF54862 2 486 5.02E-161 T 28-03-2018 CO689_RS03960 5f6ed20004167937f198cdf63e3b3e8a 522 Pfam PF14711 Respiratory nitrate reductase beta C-terminal 359 439 5.5E-28 T 28-03-2018 IPR029263 Respiratory nitrate reductase beta, C-terminal KEGG: 00910+1.7.99.4 CO689_RS03960 5f6ed20004167937f198cdf63e3b3e8a 522 Pfam PF13247 4Fe-4S dicluster domain 176 272 2.9E-35 T 28-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CO689_RS13655 89e932d96f39d2bf9d35d87828e2d8f5 239 Pfam PF06750 Bacterial Peptidase A24 N-terminal domain 13 91 1.4E-19 T 28-03-2018 IPR010627 Peptidase A24A, N-terminal CO689_RS03175 1090fbb9df87ad5c5487ff92afb8dff5 710 SUPERFAMILY SSF56712 2 585 4.45E-167 T 28-03-2018 IPR023405 DNA topoisomerase, type IA, core domain CO689_RS03175 1090fbb9df87ad5c5487ff92afb8dff5 710 Gene3D G3DSA:3.40.50.140 2 153 1.2E-42 T 28-03-2018 CO689_RS03175 1090fbb9df87ad5c5487ff92afb8dff5 710 Pfam PF01751 Toprim domain 4 134 2.8E-17 T 28-03-2018 IPR006171 TOPRIM domain CO689_RS03175 1090fbb9df87ad5c5487ff92afb8dff5 710 Gene3D G3DSA:3.30.65.10 587 635 1.0E-7 T 28-03-2018 CO689_RS03175 1090fbb9df87ad5c5487ff92afb8dff5 710 Pfam PF01131 DNA topoisomerase 154 569 8.6E-112 T 28-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CO689_RS03175 1090fbb9df87ad5c5487ff92afb8dff5 710 SMART SM00493 2 125 3.4E-18 T 28-03-2018 IPR006171 TOPRIM domain CO689_RS03175 1090fbb9df87ad5c5487ff92afb8dff5 710 Hamap MF_00953 DNA topoisomerase 3 [topB]. 2 624 61.701 T 28-03-2018 IPR005738 DNA topoisomerase III GO:0003677|GO:0003916|GO:0006265 CO689_RS03175 1090fbb9df87ad5c5487ff92afb8dff5 710 SMART SM00436 125 215 4.6E-35 T 28-03-2018 IPR003601 DNA topoisomerase, type IA, domain 2 GO:0003677|GO:0003916|GO:0006265 CO689_RS03175 1090fbb9df87ad5c5487ff92afb8dff5 710 TIGRFAM TIGR01056 topB: DNA topoisomerase III 1 698 4.2E-212 T 28-03-2018 IPR005738 DNA topoisomerase III GO:0003677|GO:0003916|GO:0006265 CO689_RS03175 1090fbb9df87ad5c5487ff92afb8dff5 710 ProSitePatterns PS00396 Prokaryotic DNA topoisomerase I active site. 294 309 - T 28-03-2018 IPR023406 DNA topoisomerase, type IA, active site GO:0003917 CO689_RS03175 1090fbb9df87ad5c5487ff92afb8dff5 710 Gene3D G3DSA:1.10.460.10 453 586 1.0E-22 T 28-03-2018 CO689_RS03175 1090fbb9df87ad5c5487ff92afb8dff5 710 Gene3D G3DSA:1.10.460.10 158 337 5.8E-39 T 28-03-2018 CO689_RS03175 1090fbb9df87ad5c5487ff92afb8dff5 710 Gene3D G3DSA:2.70.20.10 343 452 1.5E-20 T 28-03-2018 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 CO689_RS03175 1090fbb9df87ad5c5487ff92afb8dff5 710 SMART SM00437 257 535 2.2E-64 T 28-03-2018 IPR003602 DNA topoisomerase, type IA, DNA-binding domain GO:0003677|GO:0003916|GO:0006265 CO689_RS03175 1090fbb9df87ad5c5487ff92afb8dff5 710 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 300 309 1.7E-23 T 28-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CO689_RS03175 1090fbb9df87ad5c5487ff92afb8dff5 710 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 498 512 1.7E-23 T 28-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CO689_RS03175 1090fbb9df87ad5c5487ff92afb8dff5 710 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 185 203 1.7E-23 T 28-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CO689_RS03175 1090fbb9df87ad5c5487ff92afb8dff5 710 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 382 398 1.7E-23 T 28-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CO689_RS03175 1090fbb9df87ad5c5487ff92afb8dff5 710 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 99 112 1.7E-23 T 28-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CO689_RS03175 1090fbb9df87ad5c5487ff92afb8dff5 710 Gene3D G3DSA:2.20.25.10 636 674 0.012 T 28-03-2018 CO689_RS10215 c66435949d52933d2e59bab52fcf7c82 132 TIGRFAM TIGR01617 arsC_related: transcriptional regulator, Spx/MgsR family 3 114 5.3E-37 T 28-03-2018 IPR006504 Transcriptional regulator Spx/MgsR CO689_RS10215 c66435949d52933d2e59bab52fcf7c82 132 SUPERFAMILY SSF52833 1 130 8.97E-40 T 28-03-2018 IPR012336 Thioredoxin-like fold CO689_RS10215 c66435949d52933d2e59bab52fcf7c82 132 Gene3D G3DSA:3.40.30.10 1 131 2.4E-39 T 28-03-2018 CO689_RS10215 c66435949d52933d2e59bab52fcf7c82 132 Hamap MF_01132 Regulatory protein Spx [spxA]. 1 131 37.502 T 28-03-2018 IPR023731 Regulatory protein Spx GO:0045892 CO689_RS10215 c66435949d52933d2e59bab52fcf7c82 132 Pfam PF03960 ArsC family 6 113 7.2E-24 T 28-03-2018 IPR006660 Arsenate reductase-like CO689_RS13280 8e8f47fd7d5698b6cc77ba2b47e8c5d7 448 Gene3D G3DSA:3.80.30.20 140 374 2.8E-49 T 28-03-2018 IPR023404 Radical SAM, alpha/beta horseshoe CO689_RS13280 8e8f47fd7d5698b6cc77ba2b47e8c5d7 448 SUPERFAMILY SSF102114 126 364 1.07E-56 T 28-03-2018 CO689_RS13280 8e8f47fd7d5698b6cc77ba2b47e8c5d7 448 Gene3D G3DSA:3.40.50.2300 12 131 0.034 T 28-03-2018 CO689_RS13280 8e8f47fd7d5698b6cc77ba2b47e8c5d7 448 SMART SM00729 143 360 1.7E-57 T 28-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 CO689_RS13280 8e8f47fd7d5698b6cc77ba2b47e8c5d7 448 Pfam PF04055 Radical SAM superfamily 149 318 5.8E-28 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CO689_RS13280 8e8f47fd7d5698b6cc77ba2b47e8c5d7 448 Pfam PF00919 Uncharacterized protein family UPF0004 4 98 2.1E-26 T 28-03-2018 IPR013848 Methylthiotransferase, N-terminal GO:0051539 CO689_RS13280 8e8f47fd7d5698b6cc77ba2b47e8c5d7 448 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 147 167 - T 28-03-2018 IPR020612 Methylthiotransferase, conserved site GO:0051539 CO689_RS13280 8e8f47fd7d5698b6cc77ba2b47e8c5d7 448 TIGRFAM TIGR01579 MiaB-like-C: MiaB-like tRNA modifying enzyme 6 419 2.9E-143 T 28-03-2018 IPR006467 MiaB-like tRNA modifying enzyme GO:0016740 CO689_RS13280 8e8f47fd7d5698b6cc77ba2b47e8c5d7 448 Pfam PF01938 TRAM domain 377 422 1.1E-4 T 28-03-2018 IPR002792 TRAM domain CO689_RS13280 8e8f47fd7d5698b6cc77ba2b47e8c5d7 448 TIGRFAM TIGR00089 TIGR00089: radical SAM methylthiotransferase, MiaB/RimO family 3 423 1.8E-146 T 28-03-2018 IPR005839 Methylthiotransferase GO:0006400|GO:0016740|GO:0051539 CO689_RS11265 01dd99da0b692874e9c5502c51b346c5 241 SUPERFAMILY SSF55174 161 234 1.22E-31 T 28-03-2018 CO689_RS11265 01dd99da0b692874e9c5502c51b346c5 241 SUPERFAMILY SSF55174 20 110 1.22E-31 T 28-03-2018 CO689_RS11265 01dd99da0b692874e9c5502c51b346c5 241 Gene3D G3DSA:3.10.290.10 157 239 1.5E-12 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CO689_RS11265 01dd99da0b692874e9c5502c51b346c5 241 SMART SM00363 164 233 1.6E-13 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CO689_RS11265 01dd99da0b692874e9c5502c51b346c5 241 Pfam PF01479 S4 domain 164 209 1.2E-10 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CO689_RS12360 2e880e952d454b4a39b03672065e2e98 418 SUPERFAMILY SSF55729 1 165 1.43E-61 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CO689_RS12360 2e880e952d454b4a39b03672065e2e98 418 Gene3D G3DSA:3.40.630.30 1 168 1.2E-36 T 28-03-2018 CO689_RS12360 2e880e952d454b4a39b03672065e2e98 418 SUPERFAMILY SSF55729 310 410 1.09E-32 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CO689_RS12360 2e880e952d454b4a39b03672065e2e98 418 SUPERFAMILY SSF55729 167 245 1.09E-32 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CO689_RS12360 2e880e952d454b4a39b03672065e2e98 418 SUPERFAMILY SSF46589 245 309 3.19E-17 T 28-03-2018 IPR010978 tRNA-binding arm GO:0000166 CO689_RS12360 2e880e952d454b4a39b03672065e2e98 418 Gene3D G3DSA:3.40.630.30 169 390 1.6E-30 T 28-03-2018 CO689_RS12360 2e880e952d454b4a39b03672065e2e98 418 Pfam PF02388 FemAB family 6 414 2.4E-155 T 28-03-2018 IPR003447 FemABX peptidyl transferase GO:0016755|GO:0044038 CO689_RS13865 6e755bb6d161f189bae9403a0945660b 312 Pfam PF02272 DHHA1 domain 188 308 1.9E-12 T 28-03-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 CO689_RS13865 6e755bb6d161f189bae9403a0945660b 312 Pfam PF01368 DHH family 17 154 1.2E-13 T 28-03-2018 IPR001667 DDH domain KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 CO689_RS13865 6e755bb6d161f189bae9403a0945660b 312 SUPERFAMILY SSF64182 15 306 2.62E-67 T 28-03-2018 CO689_RS13865 6e755bb6d161f189bae9403a0945660b 312 Gene3D G3DSA:3.90.1640.10 1 198 5.0E-39 T 28-03-2018 CO689_RS09120 a11852ea9e2f635215d7e3c55d86bc16 213 Gene3D G3DSA:1.10.3210.10 1 213 3.3E-45 T 28-03-2018 CO689_RS09120 a11852ea9e2f635215d7e3c55d86bc16 213 SMART SM00471 26 151 0.0081 T 28-03-2018 IPR003607 HD/PDEase domain CO689_RS09120 a11852ea9e2f635215d7e3c55d86bc16 213 Pfam PF12917 HD containing hydrolase-like enzyme 1 210 3.4E-84 T 28-03-2018 IPR027366 HD containing hydrolase-like enzyme CO689_RS09120 a11852ea9e2f635215d7e3c55d86bc16 213 ProDom PD353566 UPF0207 HYDROLASE HD PHOSPHOHYDROLASE METAL-DEPENDENT SUBDOMAIN YFBR PHOSPHOHYDROLASE NUCLEOTIDE-BINDING NUCLEOSIDE 79 187 0.005 T 28-03-2018 CO689_RS09120 a11852ea9e2f635215d7e3c55d86bc16 213 SUPERFAMILY SSF109604 3 186 8.57E-35 T 28-03-2018 CO689_RS13705 84c24f3c822d9b60a4ad8dc40db0b278 229 Gene3D G3DSA:3.40.50.10090 27 134 1.6E-19 T 28-03-2018 CO689_RS13705 84c24f3c822d9b60a4ad8dc40db0b278 229 SUPERFAMILY SSF69618 19 224 1.12E-45 T 28-03-2018 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CO689_RS13705 84c24f3c822d9b60a4ad8dc40db0b278 229 Gene3D G3DSA:3.40.50.10090 135 229 4.0E-16 T 28-03-2018 CO689_RS13705 84c24f3c822d9b60a4ad8dc40db0b278 229 Pfam PF02602 Uroporphyrinogen-III synthase HemD 21 219 4.5E-39 T 28-03-2018 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CO689_RS06405 811045b2ed68dce3d3eef359439459be 441 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 413 433 9.8E-55 T 28-03-2018 CO689_RS06405 811045b2ed68dce3d3eef359439459be 441 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 246 260 9.8E-55 T 28-03-2018 CO689_RS06405 811045b2ed68dce3d3eef359439459be 441 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 39 54 9.8E-55 T 28-03-2018 CO689_RS06405 811045b2ed68dce3d3eef359439459be 441 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 125 134 9.8E-55 T 28-03-2018 CO689_RS06405 811045b2ed68dce3d3eef359439459be 441 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 391 406 9.8E-55 T 28-03-2018 CO689_RS06405 811045b2ed68dce3d3eef359439459be 441 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 5 27 9.8E-55 T 28-03-2018 CO689_RS06405 811045b2ed68dce3d3eef359439459be 441 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 162 187 9.8E-55 T 28-03-2018 CO689_RS06405 811045b2ed68dce3d3eef359439459be 441 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 326 347 9.8E-55 T 28-03-2018 CO689_RS06405 811045b2ed68dce3d3eef359439459be 441 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 289 296 9.8E-55 T 28-03-2018 CO689_RS06405 811045b2ed68dce3d3eef359439459be 441 PIRSF PIRSF000350 1 440 4.2E-91 T 28-03-2018 CO689_RS06405 811045b2ed68dce3d3eef359439459be 441 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 4 299 1.3E-61 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CO689_RS06405 811045b2ed68dce3d3eef359439459be 441 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 40 50 - T 28-03-2018 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 CO689_RS06405 811045b2ed68dce3d3eef359439459be 441 Gene3D G3DSA:3.30.390.30 329 441 7.9E-28 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CO689_RS06405 811045b2ed68dce3d3eef359439459be 441 SUPERFAMILY SSF51905 1 299 8.26E-52 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CO689_RS06405 811045b2ed68dce3d3eef359439459be 441 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 274 296 2.6E-31 T 28-03-2018 CO689_RS06405 811045b2ed68dce3d3eef359439459be 441 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 2.6E-31 T 28-03-2018 CO689_RS06405 811045b2ed68dce3d3eef359439459be 441 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 245 261 2.6E-31 T 28-03-2018 CO689_RS06405 811045b2ed68dce3d3eef359439459be 441 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 162 180 2.6E-31 T 28-03-2018 CO689_RS06405 811045b2ed68dce3d3eef359439459be 441 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 122 140 2.6E-31 T 28-03-2018 CO689_RS06405 811045b2ed68dce3d3eef359439459be 441 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 330 436 2.1E-23 T 28-03-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 CO689_RS06405 811045b2ed68dce3d3eef359439459be 441 Gene3D G3DSA:3.50.50.60 1 148 1.2E-15 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CO689_RS06405 811045b2ed68dce3d3eef359439459be 441 SUPERFAMILY SSF55424 326 439 7.73E-28 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CO689_RS06405 811045b2ed68dce3d3eef359439459be 441 Gene3D G3DSA:3.40.50.720 149 308 8.2E-39 T 28-03-2018 CO689_RS10425 cfd11d823117079f4619dab5fe41e46d 628 SUPERFAMILY SSF158911 5 86 1.96E-6 T 28-03-2018 CO689_RS10425 cfd11d823117079f4619dab5fe41e46d 628 SMART SM00725 167 288 4.7E-16 T 28-03-2018 IPR006635 NEAT domain CO689_RS10425 cfd11d823117079f4619dab5fe41e46d 628 SMART SM00725 338 453 5.8E-27 T 28-03-2018 IPR006635 NEAT domain CO689_RS10425 cfd11d823117079f4619dab5fe41e46d 628 SUPERFAMILY SSF158911 338 452 2.75E-33 T 28-03-2018 CO689_RS10425 cfd11d823117079f4619dab5fe41e46d 628 SUPERFAMILY SSF158911 150 279 2.49E-24 T 28-03-2018 CO689_RS10425 cfd11d823117079f4619dab5fe41e46d 628 Pfam PF05031 Iron Transport-associated domain 175 278 7.8E-15 T 28-03-2018 IPR006635 NEAT domain CO689_RS10425 cfd11d823117079f4619dab5fe41e46d 628 Pfam PF05031 Iron Transport-associated domain 340 446 9.4E-24 T 28-03-2018 IPR006635 NEAT domain CO689_RS07260 bad33b5d49d7af2cc106365be0c9e29c 363 Pfam PF13303 Phosphotransferase system, EIIC 40 338 5.1E-53 T 28-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 CO689_RS07910 d2628692b2efac74928f5a06424100d0 455 Gene3D G3DSA:3.90.1150.10 342 455 8.1E-12 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CO689_RS07910 d2628692b2efac74928f5a06424100d0 455 Pfam PF00392 Bacterial regulatory proteins, gntR family 5 68 2.3E-12 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CO689_RS07910 d2628692b2efac74928f5a06424100d0 455 Gene3D G3DSA:1.10.10.10 1 70 3.6E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS07910 d2628692b2efac74928f5a06424100d0 455 Pfam PF00155 Aminotransferase class I and II 124 371 2.7E-14 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CO689_RS07910 d2628692b2efac74928f5a06424100d0 455 SMART SM00345 9 68 1.1E-12 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CO689_RS07910 d2628692b2efac74928f5a06424100d0 455 SUPERFAMILY SSF53383 93 453 1.83E-66 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CO689_RS07910 d2628692b2efac74928f5a06424100d0 455 Gene3D G3DSA:3.40.640.10 138 341 4.1E-27 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CO689_RS07910 d2628692b2efac74928f5a06424100d0 455 SUPERFAMILY SSF46785 3 72 8.59E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS00975 7fd9281503a9e5efcc5bc4db3f7481c8 363 SUPERFAMILY SSF48600 4 87 3.51E-21 T 28-03-2018 IPR020822 Chorismate mutase, type II GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 CO689_RS00975 7fd9281503a9e5efcc5bc4db3f7481c8 363 Gene3D G3DSA:1.20.59.10 3 89 4.7E-25 T 28-03-2018 IPR002701 Chorismate mutase GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 CO689_RS00975 7fd9281503a9e5efcc5bc4db3f7481c8 363 Pfam PF01817 Chorismate mutase type II 9 86 2.4E-20 T 28-03-2018 IPR020822 Chorismate mutase, type II GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 CO689_RS00975 7fd9281503a9e5efcc5bc4db3f7481c8 363 TIGRFAM TIGR01801 CM_A: chorismate mutase 4 100 2.5E-41 T 28-03-2018 IPR010954 Chorismate mutase, Firmicutes/Deinococcus KEGG: 00400+2.5.1.54+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6164|MetaCyc: PWY-6627|MetaCyc: PWY-7626 CO689_RS00975 7fd9281503a9e5efcc5bc4db3f7481c8 363 Pfam PF00793 DAHP synthetase I family 110 351 9.7E-85 T 28-03-2018 IPR006218 DAHP synthetase I/KDSA GO:0009058 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 CO689_RS00975 7fd9281503a9e5efcc5bc4db3f7481c8 363 Gene3D G3DSA:3.20.20.70 95 357 4.7E-71 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CO689_RS00975 7fd9281503a9e5efcc5bc4db3f7481c8 363 SMART SM00830 9 88 1.9E-25 T 28-03-2018 IPR002701 Chorismate mutase GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 CO689_RS00975 7fd9281503a9e5efcc5bc4db3f7481c8 363 SUPERFAMILY SSF51569 62 359 1.19E-97 T 28-03-2018 CO689_RS00975 7fd9281503a9e5efcc5bc4db3f7481c8 363 TIGRFAM TIGR01361 DAHP_synth_Bsub: 3-deoxy-7-phosphoheptulonate synthase 95 351 9.0E-116 T 28-03-2018 IPR006268 Phospho-2-dehydro-3-deoxyheptonate aldolase, subtype 2 GO:0009073|GO:0016832 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 CO689_RS10925 f01b838d720f464e6a4fcd4e7ea06f8f 203 Pfam PF06335 Protein of unknown function (DUF1054) 6 202 1.6E-78 T 28-03-2018 IPR009403 Protein of unknown function UPF0637 CO689_RS10925 f01b838d720f464e6a4fcd4e7ea06f8f 203 PIRSF PIRSF021332 1 203 6.0E-84 T 28-03-2018 IPR009403 Protein of unknown function UPF0637 CO689_RS10925 f01b838d720f464e6a4fcd4e7ea06f8f 203 SUPERFAMILY SSF142913 4 202 1.36E-73 T 28-03-2018 CO689_RS10925 f01b838d720f464e6a4fcd4e7ea06f8f 203 Hamap MF_01851 UPF0637 protein . 5 203 36.276 T 28-03-2018 IPR009403 Protein of unknown function UPF0637 CO689_RS09255 7edb05a98188b501e8b92009ea275c7e 188 Gene3D G3DSA:3.20.16.10 14 181 6.8E-26 T 28-03-2018 IPR035443 Herpesvirus/Caudovirus protease domain CO689_RS09255 7edb05a98188b501e8b92009ea275c7e 188 TIGRFAM TIGR01543 proheadase_HK97: phage prohead protease, HK97 family 40 161 1.1E-22 T 28-03-2018 IPR006433 Prohead protease CO689_RS09255 7edb05a98188b501e8b92009ea275c7e 188 Pfam PF04586 Caudovirus prohead serine protease 8 164 4.2E-30 T 28-03-2018 IPR006433 Prohead protease CO689_RS04035 b34724b84302cf9375630a2af2651bff 243 Gene3D G3DSA:3.40.50.300 1 243 5.4E-75 T 28-03-2018 CO689_RS04035 b34724b84302cf9375630a2af2651bff 243 PIRSF PIRSF039085 1 242 1.8E-105 T 28-03-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 CO689_RS04035 b34724b84302cf9375630a2af2651bff 243 Pfam PF00005 ABC transporter 18 166 2.1E-37 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CO689_RS04035 b34724b84302cf9375630a2af2651bff 243 SMART SM00382 26 231 2.5E-14 T 28-03-2018 IPR003593 AAA+ ATPase domain CO689_RS04035 b34724b84302cf9375630a2af2651bff 243 SUPERFAMILY SSF52540 1 236 4.71E-80 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CO689_RS04035 b34724b84302cf9375630a2af2651bff 243 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CO689_RS01145 d0d88ee34d6f8ab19a77b5a93f63edc1 165 Gene3D G3DSA:1.10.1740.10 1 72 4.2E-8 T 28-03-2018 CO689_RS01145 d0d88ee34d6f8ab19a77b5a93f63edc1 165 SUPERFAMILY SSF88946 4 79 5.76E-8 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CO689_RS01145 d0d88ee34d6f8ab19a77b5a93f63edc1 165 Pfam PF04542 Sigma-70 region 2 7 74 7.1E-6 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CO689_RS07530 fdb4ae7faadb314ef843733f8bcdf4a0 576 Pfam PF12169 DNA polymerase III subunits gamma and tau domain III 234 347 1.2E-5 T 28-03-2018 IPR022754 DNA polymerase III, gamma subunit, domain III GO:0003887 CO689_RS07530 fdb4ae7faadb314ef843733f8bcdf4a0 576 SUPERFAMILY SSF52540 32 222 1.95E-60 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CO689_RS07530 fdb4ae7faadb314ef843733f8bcdf4a0 576 Gene3D G3DSA:1.20.272.10 243 352 2.8E-11 T 28-03-2018 CO689_RS07530 fdb4ae7faadb314ef843733f8bcdf4a0 576 SMART SM00382 37 188 4.8E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain CO689_RS07530 fdb4ae7faadb314ef843733f8bcdf4a0 576 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 41 59 6.7E-6 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 CO689_RS07530 fdb4ae7faadb314ef843733f8bcdf4a0 576 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 124 142 6.7E-6 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 CO689_RS07530 fdb4ae7faadb314ef843733f8bcdf4a0 576 TIGRFAM TIGR02397 dnaX_nterm: DNA polymerase III, subunit gamma and tau 3 346 6.1E-138 T 28-03-2018 IPR012763 DNA polymerase III, subunit gamma/ tau GO:0003887|GO:0005524|GO:0006260|GO:0009360 CO689_RS07530 fdb4ae7faadb314ef843733f8bcdf4a0 576 Gene3D G3DSA:3.40.50.300 1 166 1.5E-43 T 28-03-2018 CO689_RS07530 fdb4ae7faadb314ef843733f8bcdf4a0 576 SUPERFAMILY SSF48019 244 351 4.59E-11 T 28-03-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 CO689_RS07530 fdb4ae7faadb314ef843733f8bcdf4a0 576 Gene3D G3DSA:1.10.8.60 167 242 2.9E-19 T 28-03-2018 CO689_RS07530 fdb4ae7faadb314ef843733f8bcdf4a0 576 Pfam PF13177 DNA polymerase III, delta subunit 20 178 8.9E-48 T 28-03-2018 CO689_RS03480 d301dd091aed39b46f3a4a4a22166eb0 126 Pfam PF09685 Domain of unknown function (DUF4870) 26 125 2.6E-26 T 28-03-2018 IPR019109 Protein of unknown function DUF4870 CO689_RS04655 169619738f10788f6b2dc55e20c4a9e5 335 TIGRFAM TIGR00724 urea_amlyse_rel: biotin-dependent carboxylase uncharacterized domain 3 300 1.1E-81 T 28-03-2018 IPR003778 Carboxyltransferase domain, subdomain A and B CO689_RS04655 169619738f10788f6b2dc55e20c4a9e5 335 SUPERFAMILY SSF50891 177 291 1.04E-8 T 28-03-2018 IPR029000 Cyclophilin-like domain CO689_RS04655 169619738f10788f6b2dc55e20c4a9e5 335 Pfam PF02626 Carboxyltransferase domain, subdomain A and B 26 284 5.3E-79 T 28-03-2018 IPR003778 Carboxyltransferase domain, subdomain A and B CO689_RS04655 169619738f10788f6b2dc55e20c4a9e5 335 SMART SM00797 24 301 9.1E-117 T 28-03-2018 IPR003778 Carboxyltransferase domain, subdomain A and B CO689_RS06235 5e1b3af2c5ca79ddd7ec098f09e20cc1 229 Pfam PF13240 zinc-ribbon domain 3 24 3.8E-6 T 28-03-2018 IPR026870 Zinc-ribbon domain Reactome: R-HSA-202670 CO689_RS09360 3034470e1bb95592aa28cfbf4adaf4d4 246 Pfam PF12146 Serine aminopeptidase, S33 158 226 2.1E-7 T 28-03-2018 IPR022742 Serine aminopeptidase, S33 CO689_RS09360 3034470e1bb95592aa28cfbf4adaf4d4 246 Pfam PF12146 Serine aminopeptidase, S33 16 123 5.4E-8 T 28-03-2018 IPR022742 Serine aminopeptidase, S33 CO689_RS09360 3034470e1bb95592aa28cfbf4adaf4d4 246 SUPERFAMILY SSF53474 15 240 1.24E-32 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CO689_RS09360 3034470e1bb95592aa28cfbf4adaf4d4 246 PIRSF PIRSF017388 1 244 1.4E-86 T 28-03-2018 IPR012354 Esterase/lipase GO:0052689 CO689_RS09360 3034470e1bb95592aa28cfbf4adaf4d4 246 Gene3D G3DSA:3.40.50.1820 1 244 1.1E-38 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CO689_RS04415 2d74bb9b41dd88544f202e70b0d22930 580 Gene3D G3DSA:3.40.50.1220 192 343 1.6E-37 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CO689_RS04415 2d74bb9b41dd88544f202e70b0d22930 580 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 5 172 3.1E-34 T 28-03-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 CO689_RS04415 2d74bb9b41dd88544f202e70b0d22930 580 SUPERFAMILY SSF52518 2 171 3.24E-38 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CO689_RS04415 2d74bb9b41dd88544f202e70b0d22930 580 Gene3D G3DSA:3.40.50.970 1 191 5.1E-37 T 28-03-2018 CO689_RS04415 2d74bb9b41dd88544f202e70b0d22930 580 SUPERFAMILY SSF52518 360 553 5.53E-57 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CO689_RS04415 2d74bb9b41dd88544f202e70b0d22930 580 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 383 529 9.4E-39 T 28-03-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 CO689_RS04415 2d74bb9b41dd88544f202e70b0d22930 580 Gene3D G3DSA:3.40.50.970 344 541 1.5E-37 T 28-03-2018 CO689_RS04415 2d74bb9b41dd88544f202e70b0d22930 580 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 194 323 7.8E-35 T 28-03-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 CO689_RS04415 2d74bb9b41dd88544f202e70b0d22930 580 SUPERFAMILY SSF52467 185 356 4.52E-47 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CO689_RS04415 2d74bb9b41dd88544f202e70b0d22930 580 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 420 439 - T 28-03-2018 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 CO689_RS04090 b0c52dd56c634f1c699db95828ddbdce 506 Gene3D G3DSA:3.40.710.10 34 376 4.2E-74 T 28-03-2018 CO689_RS04090 b0c52dd56c634f1c699db95828ddbdce 506 Pfam PF00144 Beta-lactamase 49 362 1.4E-62 T 28-03-2018 IPR001466 Beta-lactamase-related CO689_RS04090 b0c52dd56c634f1c699db95828ddbdce 506 SUPERFAMILY SSF56601 46 372 5.3E-72 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CO689_RS08175 66a1da8510e3ad3095bda9ef6adfd559 181 Pfam PF01380 SIS domain 32 134 4.0E-18 T 28-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 CO689_RS08175 66a1da8510e3ad3095bda9ef6adfd559 181 SUPERFAMILY SSF53697 7 180 5.89E-34 T 28-03-2018 CO689_RS08175 66a1da8510e3ad3095bda9ef6adfd559 181 TIGRFAM TIGR03127 RuMP_HxlB: 6-phospho 3-hexuloisomerase 7 181 7.4E-67 T 28-03-2018 IPR017552 3-hexulose-6-phosphate isomerase GO:0016853 CO689_RS08175 66a1da8510e3ad3095bda9ef6adfd559 181 Gene3D G3DSA:3.40.50.10490 3 181 9.9E-37 T 28-03-2018 CO689_RS03320 eb1f760f8734623df108bd1fafae71af 206 Gene3D G3DSA:3.40.50.300 5 203 1.4E-49 T 28-03-2018 CO689_RS03320 eb1f760f8734623df108bd1fafae71af 206 SUPERFAMILY SSF52540 7 201 2.77E-52 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CO689_RS03320 eb1f760f8734623df108bd1fafae71af 206 Pfam PF00005 ABC transporter 25 154 5.2E-29 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CO689_RS03320 eb1f760f8734623df108bd1fafae71af 206 SMART SM00382 23 204 3.5E-14 T 28-03-2018 IPR003593 AAA+ ATPase domain CO689_RS03320 eb1f760f8734623df108bd1fafae71af 206 ProSitePatterns PS00211 ABC transporters family signature. 127 141 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CO689_RS03965 c1e71395c55d9e08886977cb8fc054f6 1224 ProSitePatterns PS00551 Prokaryotic molybdopterin oxidoreductases signature 1. 45 63 - T 28-03-2018 IPR027467 Molybdopterin oxidoreductase, molybdopterin cofactor binding site GO:0051539 KEGG: 00910+1.7.99.4 CO689_RS03965 c1e71395c55d9e08886977cb8fc054f6 1224 Gene3D G3DSA:2.20.25.90 52 95 2.1E-26 T 28-03-2018 CO689_RS03965 c1e71395c55d9e08886977cb8fc054f6 1224 TIGRFAM TIGR01580 narG: nitrate reductase, alpha subunit 6 1223 0.0 T 28-03-2018 IPR006468 Nitrate reductase, alpha subunit GO:0008940|GO:0009325|GO:0042126|GO:0055114 KEGG: 00910+1.7.99.4 CO689_RS03965 c1e71395c55d9e08886977cb8fc054f6 1224 Gene3D G3DSA:3.30.2070.10 782 820 9.5E-5 T 28-03-2018 CO689_RS03965 c1e71395c55d9e08886977cb8fc054f6 1224 Gene3D G3DSA:3.40.50.740 105 215 0.033 T 28-03-2018 CO689_RS03965 c1e71395c55d9e08886977cb8fc054f6 1224 Pfam PF14710 Respiratory nitrate reductase alpha N-terminal 6 37 3.3E-9 T 28-03-2018 IPR028189 Nitrate reductase, alpha subunit, N-terminal KEGG: 00910+1.7.99.4 CO689_RS03965 c1e71395c55d9e08886977cb8fc054f6 1224 SMART SM00926 40 102 8.1E-5 T 28-03-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CO689_RS03965 c1e71395c55d9e08886977cb8fc054f6 1224 SUPERFAMILY SSF53706 7 1052 0.0 T 28-03-2018 CO689_RS03965 c1e71395c55d9e08886977cb8fc054f6 1224 Gene3D G3DSA:3.40.228.10 223 645 1.4E-94 T 28-03-2018 CO689_RS03965 c1e71395c55d9e08886977cb8fc054f6 1224 SUPERFAMILY SSF50692 1072 1222 5.65E-45 T 28-03-2018 IPR009010 Aspartate decarboxylase-like domain CO689_RS03965 c1e71395c55d9e08886977cb8fc054f6 1224 Pfam PF00384 Molybdopterin oxidoreductase 105 817 8.3E-158 T 28-03-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CO689_RS03965 c1e71395c55d9e08886977cb8fc054f6 1224 Pfam PF01568 Molydopterin dinucleotide binding domain 1075 1187 5.6E-21 T 28-03-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 CO689_RS03965 c1e71395c55d9e08886977cb8fc054f6 1224 Gene3D G3DSA:2.40.40.20 1036 1224 1.5E-42 T 28-03-2018 CO689_RS13125 fa301159d8ef8124a3325aa1c0c979d0 328 Gene3D G3DSA:3.30.420.40 126 326 7.1E-55 T 28-03-2018 CO689_RS13125 fa301159d8ef8124a3325aa1c0c979d0 328 SUPERFAMILY SSF53067 4 317 1.06E-65 T 28-03-2018 CO689_RS13125 fa301159d8ef8124a3325aa1c0c979d0 328 Gene3D G3DSA:3.30.420.40 1 125 2.6E-25 T 28-03-2018 CO689_RS13125 fa301159d8ef8124a3325aa1c0c979d0 328 ProSitePatterns PS01125 ROK family signature. 140 167 - T 28-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 CO689_RS13125 fa301159d8ef8124a3325aa1c0c979d0 328 TIGRFAM TIGR00744 ROK_glcA_fam: ROK family protein (putative glucokinase) 6 326 9.1E-139 T 28-03-2018 IPR004654 Glucokinase ROK GO:0004340|GO:0005737|GO:0006096|GO:0051156 KEGG: 00010+2.7.1.2|KEGG: 00052+2.7.1.2|KEGG: 00500+2.7.1.2|KEGG: 00520+2.7.1.2|KEGG: 00521+2.7.1.2|KEGG: 00524+2.7.1.2|MetaCyc: PWY-2722|MetaCyc: PWY-2723|MetaCyc: PWY-5514|MetaCyc: PWY-5661|MetaCyc: PWY-621|MetaCyc: PWY-7238|MetaCyc: PWY-7385 CO689_RS13125 fa301159d8ef8124a3325aa1c0c979d0 328 Pfam PF00480 ROK family 7 319 5.8E-65 T 28-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 CO689_RS12800 fcfd3af152371392bb8230b25d1aea89 90 SUPERFAMILY SSF47729 1 90 3.97E-35 T 28-03-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 CO689_RS12800 fcfd3af152371392bb8230b25d1aea89 90 SMART SM00411 1 90 2.7E-51 T 28-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 CO689_RS12800 fcfd3af152371392bb8230b25d1aea89 90 ProSitePatterns PS00045 Bacterial histone-like DNA-binding proteins signature. 46 65 - T 28-03-2018 IPR020816 Histone-like DNA-binding protein, conserved site GO:0003677 CO689_RS12800 fcfd3af152371392bb8230b25d1aea89 90 PRINTS PR01727 Prokaryotic integration host factor signature 40 55 1.8E-21 T 28-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 CO689_RS12800 fcfd3af152371392bb8230b25d1aea89 90 PRINTS PR01727 Prokaryotic integration host factor signature 74 88 1.8E-21 T 28-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 CO689_RS12800 fcfd3af152371392bb8230b25d1aea89 90 PRINTS PR01727 Prokaryotic integration host factor signature 58 71 1.8E-21 T 28-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 CO689_RS12800 fcfd3af152371392bb8230b25d1aea89 90 Gene3D G3DSA:4.10.520.10 1 90 4.4E-38 T 28-03-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 CO689_RS12800 fcfd3af152371392bb8230b25d1aea89 90 Pfam PF00216 Bacterial DNA-binding protein 1 90 9.0E-37 T 28-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 CO689_RS06925 2e2d5dbbb89ffddefc0b349495a5d156 609 Pfam PF00989 PAS fold 264 366 1.2E-8 T 28-03-2018 IPR013767 PAS fold GO:0006355 CO689_RS06925 2e2d5dbbb89ffddefc0b349495a5d156 609 PRINTS PR00344 Bacterial sensor protein C-terminal signature 543 553 4.3E-18 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CO689_RS06925 2e2d5dbbb89ffddefc0b349495a5d156 609 PRINTS PR00344 Bacterial sensor protein C-terminal signature 525 539 4.3E-18 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CO689_RS06925 2e2d5dbbb89ffddefc0b349495a5d156 609 PRINTS PR00344 Bacterial sensor protein C-terminal signature 560 578 4.3E-18 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CO689_RS06925 2e2d5dbbb89ffddefc0b349495a5d156 609 PRINTS PR00344 Bacterial sensor protein C-terminal signature 584 597 4.3E-18 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CO689_RS06925 2e2d5dbbb89ffddefc0b349495a5d156 609 Gene3D G3DSA:3.30.450.20 249 371 4.4E-23 T 28-03-2018 CO689_RS06925 2e2d5dbbb89ffddefc0b349495a5d156 609 SMART SM00091 263 329 1.5E-8 T 28-03-2018 IPR000014 PAS domain CO689_RS06925 2e2d5dbbb89ffddefc0b349495a5d156 609 SMART SM00388 375 442 5.4E-21 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CO689_RS06925 2e2d5dbbb89ffddefc0b349495a5d156 609 SUPERFAMILY SSF55874 431 600 5.63E-45 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CO689_RS06925 2e2d5dbbb89ffddefc0b349495a5d156 609 Pfam PF00512 His Kinase A (phospho-acceptor) domain 376 441 2.7E-18 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CO689_RS06925 2e2d5dbbb89ffddefc0b349495a5d156 609 SUPERFAMILY SSF47384 360 442 6.08E-21 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CO689_RS06925 2e2d5dbbb89ffddefc0b349495a5d156 609 Gene3D G3DSA:3.30.565.10 449 600 1.9E-42 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CO689_RS06925 2e2d5dbbb89ffddefc0b349495a5d156 609 SMART SM00387 486 600 3.3E-38 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CO689_RS06925 2e2d5dbbb89ffddefc0b349495a5d156 609 Gene3D G3DSA:3.30.450.20 33 181 2.8E-9 T 28-03-2018 CO689_RS06925 2e2d5dbbb89ffddefc0b349495a5d156 609 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 261 375 1.6E-11 T 28-03-2018 IPR000014 PAS domain CO689_RS06925 2e2d5dbbb89ffddefc0b349495a5d156 609 SMART SM00304 204 256 2.2E-14 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CO689_RS06925 2e2d5dbbb89ffddefc0b349495a5d156 609 Pfam PF00672 HAMP domain 204 252 9.8E-11 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CO689_RS06925 2e2d5dbbb89ffddefc0b349495a5d156 609 SUPERFAMILY SSF158472 204 253 7.85E-10 T 28-03-2018 CO689_RS06925 2e2d5dbbb89ffddefc0b349495a5d156 609 Gene3D G3DSA:1.10.287.130 372 438 1.2E-18 T 28-03-2018 CO689_RS06925 2e2d5dbbb89ffddefc0b349495a5d156 609 SUPERFAMILY SSF55785 252 367 3.32E-13 T 28-03-2018 IPR000014 PAS domain CO689_RS06925 2e2d5dbbb89ffddefc0b349495a5d156 609 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 487 598 1.3E-25 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CO689_RS12730 866c1faf50940589de410778fd27a0cc 399 SUPERFAMILY SSF81891 141 397 3.14E-48 T 28-03-2018 CO689_RS12730 866c1faf50940589de410778fd27a0cc 399 SUPERFAMILY SSF81301 8 140 9.81E-42 T 28-03-2018 CO689_RS12730 866c1faf50940589de410778fd27a0cc 399 Gene3D G3DSA:3.30.460.10 2 142 6.5E-46 T 28-03-2018 CO689_RS12730 866c1faf50940589de410778fd27a0cc 399 Gene3D G3DSA:1.10.3090.10 143 399 1.1E-36 T 28-03-2018 CO689_RS12730 866c1faf50940589de410778fd27a0cc 399 Hamap MF_01263 CCA-adding enzyme [cca]. 3 399 36.36 T 28-03-2018 IPR023068 CCA-adding enzyme, firmicutes GO:0001680|GO:0004810|GO:0016437 CO689_RS12730 866c1faf50940589de410778fd27a0cc 399 Pfam PF13735 tRNA nucleotidyltransferase domain 2 putative 251 395 4.0E-24 T 28-03-2018 IPR032810 CCA-adding enzyme, C-terminal CO689_RS12730 866c1faf50940589de410778fd27a0cc 399 Pfam PF12627 Probable RNA and SrmB- binding site of polymerase A 170 228 3.0E-8 T 28-03-2018 IPR032828 tRNA nucleotidyltransferase/poly(A) polymerase, RNA and SrmB- binding domain Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 CO689_RS12730 866c1faf50940589de410778fd27a0cc 399 Pfam PF01743 Poly A polymerase head domain 23 142 8.1E-35 T 28-03-2018 IPR002646 Poly A polymerase, head domain GO:0003723|GO:0006396|GO:0016779 Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 CO689_RS05530 266103edd62bdb8d056d70c559a866be 246 SUPERFAMILY SSF160104 4 244 4.97E-76 T 28-03-2018 IPR023375 Acetoacetate decarboxylase beta barrel domain KEGG: 00072+4.1.1.4|KEGG: 00640+4.1.1.4|MetaCyc: PWY-5451|MetaCyc: PWY-6588|MetaCyc: PWY-6876|MetaCyc: PWY-7466 CO689_RS05530 266103edd62bdb8d056d70c559a866be 246 Gene3D G3DSA:2.40.400.10 13 244 1.5E-56 T 28-03-2018 IPR023375 Acetoacetate decarboxylase beta barrel domain KEGG: 00072+4.1.1.4|KEGG: 00640+4.1.1.4|MetaCyc: PWY-5451|MetaCyc: PWY-6588|MetaCyc: PWY-6876|MetaCyc: PWY-7466 CO689_RS05530 266103edd62bdb8d056d70c559a866be 246 Pfam PF06314 Acetoacetate decarboxylase (ADC) 12 243 1.3E-66 T 28-03-2018 IPR010451 Acetoacetate decarboxylase GO:0016829 KEGG: 00072+4.1.1.4|KEGG: 00640+4.1.1.4|MetaCyc: PWY-5451|MetaCyc: PWY-6588|MetaCyc: PWY-6876|MetaCyc: PWY-7466 CO689_RS03355 c8e30229c9c6bcaf21d8219516e95856 269 TIGRFAM TIGR00129 fdhD_narQ: formate dehydrogenase family accessory protein FdhD 25 263 6.8E-72 T 28-03-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 CO689_RS03355 c8e30229c9c6bcaf21d8219516e95856 269 Gene3D G3DSA:3.10.20.10 31 112 1.1E-16 T 28-03-2018 CO689_RS03355 c8e30229c9c6bcaf21d8219516e95856 269 Hamap MF_00187 Sulfurtransferase FdhD [fdhD]. 5 263 30.585 T 28-03-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 CO689_RS03355 c8e30229c9c6bcaf21d8219516e95856 269 Pfam PF02634 FdhD/NarQ family 29 262 1.3E-72 T 28-03-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 CO689_RS03355 c8e30229c9c6bcaf21d8219516e95856 269 Gene3D G3DSA:3.40.140.10 128 267 4.3E-47 T 28-03-2018 CO689_RS03355 c8e30229c9c6bcaf21d8219516e95856 269 SUPERFAMILY SSF53927 8 262 2.05E-74 T 28-03-2018 IPR016193 Cytidine deaminase-like GO:0003824 CO689_RS03355 c8e30229c9c6bcaf21d8219516e95856 269 PIRSF PIRSF015626 1 266 1.2E-73 T 28-03-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 CO689_RS13325 cebf0cf96655236b069cf2017a48be85 83 Hamap MF_00500 30S ribosomal protein S20 [rpsT]. 1 82 11.984 T 28-03-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 CO689_RS13325 cebf0cf96655236b069cf2017a48be85 83 Gene3D G3DSA:1.20.58.110 1 83 5.0E-19 T 28-03-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 CO689_RS13325 cebf0cf96655236b069cf2017a48be85 83 SUPERFAMILY SSF46992 3 83 4.19E-20 T 28-03-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 CO689_RS13325 cebf0cf96655236b069cf2017a48be85 83 Pfam PF01649 Ribosomal protein S20 2 80 1.7E-19 T 28-03-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 CO689_RS13325 cebf0cf96655236b069cf2017a48be85 83 TIGRFAM TIGR00029 S20: ribosomal protein bS20 1 81 2.9E-18 T 28-03-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 CO689_RS13325 cebf0cf96655236b069cf2017a48be85 83 ProDom PD004231 RIBOSOMAL S20 30S RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN S20P SUBUNIT CHLOROPLAST DIRECT 12 78 3.0E-8 T 28-03-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 CO689_RS00835 2b5229f17224ce02266ff69aca1b75af 444 Pfam PF05598 Transposase domain (DUF772) 52 127 3.1E-21 T 28-03-2018 IPR008490 Transposase InsH, N-terminal CO689_RS00835 2b5229f17224ce02266ff69aca1b75af 444 Pfam PF13751 Transposase DDE domain 321 439 1.9E-22 T 28-03-2018 IPR025668 Transposase DDE domain CO689_RS02855 2b5229f17224ce02266ff69aca1b75af 444 Pfam PF05598 Transposase domain (DUF772) 52 127 3.1E-21 T 28-03-2018 IPR008490 Transposase InsH, N-terminal CO689_RS02855 2b5229f17224ce02266ff69aca1b75af 444 Pfam PF13751 Transposase DDE domain 321 439 1.9E-22 T 28-03-2018 IPR025668 Transposase DDE domain CO689_RS11910 5df9b07c21a0d814aa0a3e5525596e9d 573 Gene3D G3DSA:3.40.190.10 214 321 5.9E-23 T 28-03-2018 CO689_RS11910 5df9b07c21a0d814aa0a3e5525596e9d 573 Gene3D G3DSA:3.10.105.10 322 541 2.4E-51 T 28-03-2018 CO689_RS11910 5df9b07c21a0d814aa0a3e5525596e9d 573 Gene3D G3DSA:3.90.76.10 56 213 7.8E-28 T 28-03-2018 CO689_RS11910 5df9b07c21a0d814aa0a3e5525596e9d 573 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 96 484 2.3E-85 T 28-03-2018 IPR000914 Solute-binding protein family 5 domain CO689_RS11910 5df9b07c21a0d814aa0a3e5525596e9d 573 PIRSF PIRSF002741 2 573 1.2E-103 T 28-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 CO689_RS11910 5df9b07c21a0d814aa0a3e5525596e9d 573 SUPERFAMILY SSF53850 43 571 3.73E-115 T 28-03-2018 CO689_RS01195 bbb5f0a1145dd5c9d3ebb976c31dec28 530 PIRSF PIRSF006294 2 528 3.9E-240 T 28-03-2018 IPR001272 Phosphoenolpyruvate carboxykinase, ATP-utilising GO:0004612|GO:0005524|GO:0006094 KEGG: 00010+4.1.1.49|KEGG: 00020+4.1.1.49|KEGG: 00620+4.1.1.49|KEGG: 00710+4.1.1.49|MetaCyc: PWY-561|MetaCyc: PWY-7117 CO689_RS01195 bbb5f0a1145dd5c9d3ebb976c31dec28 530 Hamap MF_00453 Phosphoenolpyruvate carboxykinase (ATP) [pckA]. 14 530 55.688 T 28-03-2018 IPR001272 Phosphoenolpyruvate carboxykinase, ATP-utilising GO:0004612|GO:0005524|GO:0006094 KEGG: 00010+4.1.1.49|KEGG: 00020+4.1.1.49|KEGG: 00620+4.1.1.49|KEGG: 00710+4.1.1.49|MetaCyc: PWY-561|MetaCyc: PWY-7117 CO689_RS01195 bbb5f0a1145dd5c9d3ebb976c31dec28 530 SUPERFAMILY SSF53795 216 525 7.1E-132 T 28-03-2018 CO689_RS01195 bbb5f0a1145dd5c9d3ebb976c31dec28 530 Gene3D G3DSA:3.40.449.10 22 214 2.2E-77 T 28-03-2018 IPR008210 Phosphoenolpyruvate carboxykinase, N-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 CO689_RS01195 bbb5f0a1145dd5c9d3ebb976c31dec28 530 Gene3D G3DSA:3.90.228.20 216 294 2.6E-29 T 28-03-2018 IPR013035 Phosphoenolpyruvate carboxykinase, C-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 CO689_RS01195 bbb5f0a1145dd5c9d3ebb976c31dec28 530 Gene3D G3DSA:3.90.228.20 295 527 1.1E-98 T 28-03-2018 IPR013035 Phosphoenolpyruvate carboxykinase, C-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 CO689_RS01195 bbb5f0a1145dd5c9d3ebb976c31dec28 530 SUPERFAMILY SSF68923 15 215 1.92E-76 T 28-03-2018 IPR008210 Phosphoenolpyruvate carboxykinase, N-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 CO689_RS01195 bbb5f0a1145dd5c9d3ebb976c31dec28 530 TIGRFAM TIGR00224 pckA: phosphoenolpyruvate carboxykinase (ATP) 25 527 7.6E-239 T 28-03-2018 IPR001272 Phosphoenolpyruvate carboxykinase, ATP-utilising GO:0004612|GO:0005524|GO:0006094 KEGG: 00010+4.1.1.49|KEGG: 00020+4.1.1.49|KEGG: 00620+4.1.1.49|KEGG: 00710+4.1.1.49|MetaCyc: PWY-561|MetaCyc: PWY-7117 CO689_RS01195 bbb5f0a1145dd5c9d3ebb976c31dec28 530 Pfam PF01293 Phosphoenolpyruvate carboxykinase 23 482 1.3E-220 T 28-03-2018 IPR001272 Phosphoenolpyruvate carboxykinase, ATP-utilising GO:0004612|GO:0005524|GO:0006094 KEGG: 00010+4.1.1.49|KEGG: 00020+4.1.1.49|KEGG: 00620+4.1.1.49|KEGG: 00710+4.1.1.49|MetaCyc: PWY-561|MetaCyc: PWY-7117 CO689_RS03470 14b5017dc5ffaa6ffce8a228a4dadf28 472 TIGRFAM TIGR00931 antiport_nhaC: Na+/H+ antiporter NhaC 3 461 8.5E-133 T 28-03-2018 IPR004770 Na+/H+ antiporter NhaC GO:0015297|GO:0016021 CO689_RS03470 14b5017dc5ffaa6ffce8a228a4dadf28 472 Pfam PF03553 Na+/H+ antiporter family 157 455 4.9E-58 T 28-03-2018 IPR018461 Na+/H+ antiporter, NhaC-like, C-terminal GO:0016021 CO689_RS10460 be3b4b2f751067bc6d55512f7d0efc39 111 SUPERFAMILY SSF54909 1 98 8.72E-20 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel CO689_RS10460 be3b4b2f751067bc6d55512f7d0efc39 111 Gene3D G3DSA:3.30.70.100 1 104 5.5E-15 T 28-03-2018 CO689_RS10460 be3b4b2f751067bc6d55512f7d0efc39 111 Pfam PF03992 Antibiotic biosynthesis monooxygenase 1 77 8.1E-12 T 28-03-2018 IPR007138 Antibiotic biosynthesis monooxygenase domain CO689_RS11365 f17b67517341e9c6fdd72d37188199d7 234 Pfam PF00215 Orotidine 5'-phosphate decarboxylase / HUMPS family 10 226 3.7E-46 T 28-03-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CO689_RS11365 f17b67517341e9c6fdd72d37188199d7 234 Gene3D G3DSA:3.20.20.70 6 233 1.3E-59 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CO689_RS11365 f17b67517341e9c6fdd72d37188199d7 234 Hamap MF_01200_B Orotidine 5'-phosphate decarboxylase [pyrF]. 6 233 38.406 T 28-03-2018 IPR014732 Orotidine 5'-phosphate decarboxylase GO:0004590|GO:0044205 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CO689_RS11365 f17b67517341e9c6fdd72d37188199d7 234 ProSitePatterns PS00156 Orotidine 5'-phosphate decarboxylase active site. 59 72 - T 28-03-2018 IPR018089 Orotidine 5'-phosphate decarboxylase, active site GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CO689_RS11365 f17b67517341e9c6fdd72d37188199d7 234 SUPERFAMILY SSF51366 8 232 3.33E-68 T 28-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 CO689_RS11365 f17b67517341e9c6fdd72d37188199d7 234 TIGRFAM TIGR01740 pyrF: orotidine 5'-phosphate decarboxylase 9 228 1.3E-61 T 28-03-2018 IPR014732 Orotidine 5'-phosphate decarboxylase GO:0004590|GO:0044205 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CO689_RS11365 f17b67517341e9c6fdd72d37188199d7 234 SMART SM00934 8 228 1.1E-87 T 28-03-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CO689_RS04125 49cd0da4f2cfbf6cf516b28f0655522e 120 Pfam PF11345 Protein of unknown function (DUF3147) 4 111 1.1E-33 T 28-03-2018 IPR021493 Protein of unknown function DUF3147 CO689_RS10065 3a798904c950bc26c322be406c0e0bf9 414 SUPERFAMILY SSF51735 181 413 9.25E-75 T 28-03-2018 IPR016040 NAD(P)-binding domain CO689_RS10065 3a798904c950bc26c322be406c0e0bf9 414 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 340 351 2.3E-29 T 28-03-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CO689_RS10065 3a798904c950bc26c322be406c0e0bf9 414 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 172 194 2.3E-29 T 28-03-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CO689_RS10065 3a798904c950bc26c322be406c0e0bf9 414 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 214 234 2.3E-29 T 28-03-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CO689_RS10065 3a798904c950bc26c322be406c0e0bf9 414 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 92 106 2.3E-29 T 28-03-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CO689_RS10065 3a798904c950bc26c322be406c0e0bf9 414 SUPERFAMILY SSF53223 5 183 6.72E-67 T 28-03-2018 CO689_RS10065 3a798904c950bc26c322be406c0e0bf9 414 Gene3D G3DSA:3.40.50.720 181 414 3.3E-72 T 28-03-2018 CO689_RS10065 3a798904c950bc26c322be406c0e0bf9 414 ProSitePatterns PS00074 Glu / Leu / Phe / Val dehydrogenases active site. 100 113 - T 28-03-2018 IPR033524 Leu/Phe/Val dehydrogenases active site Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CO689_RS10065 3a798904c950bc26c322be406c0e0bf9 414 PIRSF PIRSF000185 2 414 6.9E-168 T 28-03-2018 IPR014362 Glutamate dehydrogenase GO:0016639|GO:0055114 CO689_RS10065 3a798904c950bc26c322be406c0e0bf9 414 Pfam PF02812 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain 36 162 1.2E-55 T 28-03-2018 IPR006097 Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CO689_RS10065 3a798904c950bc26c322be406c0e0bf9 414 Gene3D G3DSA:3.40.50.10860 33 167 6.7E-52 T 28-03-2018 CO689_RS10065 3a798904c950bc26c322be406c0e0bf9 414 SMART SM00839 183 412 1.5E-92 T 28-03-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CO689_RS10065 3a798904c950bc26c322be406c0e0bf9 414 Pfam PF00208 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 181 412 3.3E-73 T 28-03-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CO689_RS02220 fab288440d293a6e7adf7cc67fb88d67 422 TIGRFAM TIGR02079 THD1: threonine dehydratase 10 422 1.1E-186 T 28-03-2018 IPR011820 L-threonine dehydratase biosynthetic IlvA GO:0004794 KEGG: 00260+4.3.1.19|KEGG: 00290+4.3.1.19 CO689_RS02220 fab288440d293a6e7adf7cc67fb88d67 422 Gene3D G3DSA:3.40.1020.10 231 422 1.7E-34 T 28-03-2018 CO689_RS02220 fab288440d293a6e7adf7cc67fb88d67 422 Pfam PF00585 C-terminal regulatory domain of Threonine dehydratase 329 421 1.4E-22 T 28-03-2018 IPR001721 ACT-like domain KEGG: 00260+4.3.1.19|KEGG: 00290+4.3.1.19 CO689_RS02220 fab288440d293a6e7adf7cc67fb88d67 422 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 21 316 7.9E-77 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CO689_RS02220 fab288440d293a6e7adf7cc67fb88d67 422 Gene3D G3DSA:3.40.50.1100 17 178 8.3E-42 T 28-03-2018 CO689_RS02220 fab288440d293a6e7adf7cc67fb88d67 422 SUPERFAMILY SSF53686 10 366 5.63E-98 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CO689_RS02220 fab288440d293a6e7adf7cc67fb88d67 422 SUPERFAMILY SSF55021 339 417 1.17E-10 T 28-03-2018 CO689_RS02220 fab288440d293a6e7adf7cc67fb88d67 422 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 47 60 - T 28-03-2018 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 CO689_RS03920 84373dd901879f28fde3d556f1b7302e 389 TIGRFAM TIGR01835 HMG-CoA-S_prok: hydroxymethylglutaryl-CoA synthase 3 385 3.6E-157 T 28-03-2018 IPR011554 Hydroxymethylglutaryl-CoA synthase, prokaryotic KEGG: 00072+2.3.3.10|KEGG: 00280+2.3.3.10|KEGG: 00650+2.3.3.10|KEGG: 00900+2.3.3.10|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7571|MetaCyc: PWY-922 CO689_RS03920 84373dd901879f28fde3d556f1b7302e 389 Pfam PF01154 Hydroxymethylglutaryl-coenzyme A synthase N terminal 3 164 4.8E-18 T 28-03-2018 IPR013528 Hydroxymethylglutaryl-coenzyme A synthase, N-terminal GO:0004421|GO:0008299 Reactome: R-HSA-1989781 CO689_RS03920 84373dd901879f28fde3d556f1b7302e 389 Gene3D G3DSA:3.40.47.10 175 320 3.6E-47 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CO689_RS03920 84373dd901879f28fde3d556f1b7302e 389 Gene3D G3DSA:3.40.47.10 15 171 8.4E-11 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CO689_RS03920 84373dd901879f28fde3d556f1b7302e 389 SUPERFAMILY SSF53901 169 387 1.23E-69 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CO689_RS03920 84373dd901879f28fde3d556f1b7302e 389 Pfam PF08540 Hydroxymethylglutaryl-coenzyme A synthase C terminal 266 384 4.1E-15 T 28-03-2018 IPR013746 Hydroxymethylglutaryl-coenzyme A synthase C-terminal domain GO:0004421|GO:0008299 KEGG: 00072+2.3.3.10|KEGG: 00280+2.3.3.10|KEGG: 00650+2.3.3.10|KEGG: 00900+2.3.3.10|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7571|MetaCyc: PWY-922|Reactome: R-HSA-1989781 CO689_RS03920 84373dd901879f28fde3d556f1b7302e 389 SUPERFAMILY SSF53901 3 166 3.37E-44 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CO689_RS00270 0877b3970c314bbb289c906e980eadfd 285 Pfam PF10035 Uncharacterized protein conserved in bacteria (DUF2179) 241 275 1.0E-10 T 28-03-2018 IPR019264 Domain of unknown function DUF2179 CO689_RS00270 0877b3970c314bbb289c906e980eadfd 285 Pfam PF02588 Uncharacterised 5xTM membrane BCR, YitT family COG1284 13 216 9.1E-51 T 28-03-2018 IPR003740 Uncharacterised membrane protein YitT CO689_RS00270 0877b3970c314bbb289c906e980eadfd 285 PIRSF PIRSF006483 1 284 2.2E-68 T 28-03-2018 IPR003740 Uncharacterised membrane protein YitT CO689_RS01965 85dd9ee3b08495ef1df77509b44d9160 126 SMART SM00345 17 76 1.6E-14 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CO689_RS01965 85dd9ee3b08495ef1df77509b44d9160 126 SUPERFAMILY SSF46785 6 80 3.08E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS01965 85dd9ee3b08495ef1df77509b44d9160 126 Gene3D G3DSA:1.10.10.10 1 90 3.5E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS01965 85dd9ee3b08495ef1df77509b44d9160 126 Pfam PF00392 Bacterial regulatory proteins, gntR family 14 76 5.2E-17 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CO689_RS07600 4a7aa2b4f9fbcb60c7b2a73672bdad7b 278 PIRSF PIRSF005917 1 278 5.8E-100 T 28-03-2018 IPR008189 rRNA small subunit methyltransferase I GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CO689_RS07600 4a7aa2b4f9fbcb60c7b2a73672bdad7b 278 TIGRFAM TIGR00096 TIGR00096: 16S rRNA (cytidine(1402)-2'-O)-methyltransferase 4 275 8.4E-80 T 28-03-2018 IPR008189 rRNA small subunit methyltransferase I GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CO689_RS07600 4a7aa2b4f9fbcb60c7b2a73672bdad7b 278 Gene3D G3DSA:3.30.950.10 112 226 5.0E-31 T 28-03-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CO689_RS07600 4a7aa2b4f9fbcb60c7b2a73672bdad7b 278 ProSitePatterns PS01296 RsmI AdoMet-dependent methyltransferase protein family signature. 81 92 - T 28-03-2018 IPR018063 SAM-dependent methyltransferase RsmI, conserved site GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CO689_RS07600 4a7aa2b4f9fbcb60c7b2a73672bdad7b 278 Hamap MF_01877 Ribosomal RNA small subunit methyltransferase I [rsmI]. 3 223 35.943 T 28-03-2018 IPR008189 rRNA small subunit methyltransferase I GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CO689_RS07600 4a7aa2b4f9fbcb60c7b2a73672bdad7b 278 SUPERFAMILY SSF53790 1 221 1.22E-78 T 28-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CO689_RS07600 4a7aa2b4f9fbcb60c7b2a73672bdad7b 278 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 3 202 6.1E-30 T 28-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CO689_RS07600 4a7aa2b4f9fbcb60c7b2a73672bdad7b 278 Gene3D G3DSA:3.40.1010.10 1 111 5.0E-44 T 28-03-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CO689_RS10720 2e37602a5098106f05cce1bcdedd84c9 375 TIGRFAM TIGR01161 purK: phosphoribosylaminoimidazole carboxylase, ATPase subunit 11 364 2.4E-110 T 28-03-2018 IPR005875 Phosphoribosylaminoimidazole carboxylase, ATPase subunit GO:0004638|GO:0006189 CO689_RS10720 2e37602a5098106f05cce1bcdedd84c9 375 SUPERFAMILY SSF51246 308 366 1.73E-15 T 28-03-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 CO689_RS10720 2e37602a5098106f05cce1bcdedd84c9 375 Gene3D G3DSA:3.30.1490.20 123 185 1.9E-19 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CO689_RS10720 2e37602a5098106f05cce1bcdedd84c9 375 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 9 76 7.7E-7 T 28-03-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 CO689_RS10720 2e37602a5098106f05cce1bcdedd84c9 375 SUPERFAMILY SSF56059 107 302 5.48E-57 T 28-03-2018 CO689_RS10720 2e37602a5098106f05cce1bcdedd84c9 375 Hamap MF_01928 N5-carboxyaminoimidazole ribonucleotide synthase [purK]. 11 359 39.286 T 28-03-2018 IPR005875 Phosphoribosylaminoimidazole carboxylase, ATPase subunit GO:0004638|GO:0006189 CO689_RS10720 2e37602a5098106f05cce1bcdedd84c9 375 Pfam PF02222 ATP-grasp domain 116 283 1.0E-44 T 28-03-2018 IPR003135 ATP-grasp fold, ATP-dependent carboxylate-amine ligase-type CO689_RS10720 2e37602a5098106f05cce1bcdedd84c9 375 SUPERFAMILY SSF52440 11 104 1.44E-27 T 28-03-2018 IPR016185 Pre-ATP-grasp domain CO689_RS10720 2e37602a5098106f05cce1bcdedd84c9 375 Gene3D G3DSA:3.30.470.20 186 371 1.9E-32 T 28-03-2018 CO689_RS10720 2e37602a5098106f05cce1bcdedd84c9 375 Gene3D G3DSA:3.40.50.20 10 95 3.1E-25 T 28-03-2018 CO689_RS05810 8b836f944b1cf12d30b7d8566012dda8 477 Pfam PF12698 ABC-2 family transporter protein 23 463 1.1E-21 T 28-03-2018 CO689_RS05810 8b836f944b1cf12d30b7d8566012dda8 477 TIGRFAM TIGR03061 pip_yhgE_Nterm: YhgE/Pip N-terminal domain 4 166 2.7E-50 T 28-03-2018 IPR017500 Phage infection protein, YhgE, N-terminal CO689_RS05810 8b836f944b1cf12d30b7d8566012dda8 477 Gene3D G3DSA:3.40.1710.10 40 211 3.9E-22 T 28-03-2018 CO689_RS05810 8b836f944b1cf12d30b7d8566012dda8 477 TIGRFAM TIGR03062 pip_yhgE_Cterm: YhgE/Pip C-terminal domain 269 461 2.8E-44 T 28-03-2018 IPR017501 Phage infection protein, YhgE, C-terminal CO689_RS05125 8fe4694587f1e554f895e1a986abddee 141 Pfam PF04039 Domain related to MnhB subunit of Na+/H+ antiporter 7 131 8.3E-30 T 28-03-2018 IPR007182 Na+/H+ antiporter MnhB subunit-related protein CO689_RS13750 53ecd8fea1cd86516d6878f5a6d69d43 118 ProSitePatterns PS00937 Ribosomal protein L20 signature. 54 70 - T 28-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CO689_RS13750 53ecd8fea1cd86516d6878f5a6d69d43 118 PRINTS PR00062 Ribosomal protein L20 signature 75 101 4.8E-41 T 28-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CO689_RS13750 53ecd8fea1cd86516d6878f5a6d69d43 118 PRINTS PR00062 Ribosomal protein L20 signature 12 41 4.8E-41 T 28-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CO689_RS13750 53ecd8fea1cd86516d6878f5a6d69d43 118 PRINTS PR00062 Ribosomal protein L20 signature 42 71 4.8E-41 T 28-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CO689_RS13750 53ecd8fea1cd86516d6878f5a6d69d43 118 SUPERFAMILY SSF74731 2 117 1.83E-50 T 28-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CO689_RS13750 53ecd8fea1cd86516d6878f5a6d69d43 118 ProDom PD002389 RIBOSOMAL RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN L20 50S L20 CHLOROPLAST BACTERIAL ORGANELLE 20 72 3.0E-15 T 28-03-2018 CO689_RS13750 53ecd8fea1cd86516d6878f5a6d69d43 118 Pfam PF00453 Ribosomal protein L20 3 109 9.5E-50 T 28-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CO689_RS13750 53ecd8fea1cd86516d6878f5a6d69d43 118 Gene3D G3DSA:1.10.1900.20 55 116 2.2E-30 T 28-03-2018 IPR035566 Ribosomal protein L20 C-terminal domain Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CO689_RS13750 53ecd8fea1cd86516d6878f5a6d69d43 118 TIGRFAM TIGR01032 rplT_bact: ribosomal protein bL20 1 114 1.1E-52 T 28-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CO689_RS13750 53ecd8fea1cd86516d6878f5a6d69d43 118 Hamap MF_00382 50S ribosomal protein L20 [rplT]. 2 115 30.133 T 28-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CO689_RS05875 9bc0780e6c9fc53e197de074d620072f 61 SUPERFAMILY SSF47413 2 60 1.29E-19 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CO689_RS05875 9bc0780e6c9fc53e197de074d620072f 61 Pfam PF01381 Helix-turn-helix 5 59 2.2E-19 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CO689_RS05875 9bc0780e6c9fc53e197de074d620072f 61 SMART SM00530 4 59 1.5E-17 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CO689_RS05875 9bc0780e6c9fc53e197de074d620072f 61 Gene3D G3DSA:1.10.260.40 1 61 1.6E-19 T 28-03-2018 CO689_RS03650 f813fdfea6550e417ab2e4f32f6ad163 309 Pfam PF00491 Arginase family 46 307 5.0E-52 T 28-03-2018 IPR006035 Ureohydrolase GO:0046872 CO689_RS03650 f813fdfea6550e417ab2e4f32f6ad163 309 Gene3D G3DSA:3.40.800.10 1 309 2.7E-75 T 28-03-2018 CO689_RS03650 f813fdfea6550e417ab2e4f32f6ad163 309 SUPERFAMILY SSF52768 9 308 5.04E-73 T 28-03-2018 CO689_RS03650 f813fdfea6550e417ab2e4f32f6ad163 309 PIRSF PIRSF036979 20 309 2.1E-34 T 28-03-2018 IPR006035 Ureohydrolase GO:0046872 CO689_RS03650 f813fdfea6550e417ab2e4f32f6ad163 309 Hamap MF_00737 Formimidoylglutamase [hutG]. 5 309 37.136 T 28-03-2018 IPR005923 Formiminoglutamase GO:0019556|GO:0050415 KEGG: 00340+3.5.3.8 CO689_RS03650 f813fdfea6550e417ab2e4f32f6ad163 309 TIGRFAM TIGR01227 hutG: formimidoylglutamase 10 308 5.8E-107 T 28-03-2018 IPR005923 Formiminoglutamase GO:0019556|GO:0050415 KEGG: 00340+3.5.3.8 CO689_RS05130 4d613cfc19ff37b317e71e07fe771430 827 Pfam PF00662 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus 88 141 5.7E-12 T 28-03-2018 IPR001516 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminal Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CO689_RS05130 4d613cfc19ff37b317e71e07fe771430 827 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 102 127 6.8E-45 T 28-03-2018 CO689_RS05130 4d613cfc19ff37b317e71e07fe771430 827 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 131 151 6.8E-45 T 28-03-2018 CO689_RS05130 4d613cfc19ff37b317e71e07fe771430 827 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 463 482 6.8E-45 T 28-03-2018 CO689_RS05130 4d613cfc19ff37b317e71e07fe771430 827 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 336 348 6.8E-45 T 28-03-2018 CO689_RS05130 4d613cfc19ff37b317e71e07fe771430 827 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 268 294 6.8E-45 T 28-03-2018 CO689_RS05130 4d613cfc19ff37b317e71e07fe771430 827 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 178 199 6.8E-45 T 28-03-2018 CO689_RS05130 4d613cfc19ff37b317e71e07fe771430 827 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 246 267 6.8E-45 T 28-03-2018 CO689_RS05130 4d613cfc19ff37b317e71e07fe771430 827 Pfam PF00361 Proton-conducting membrane transporter 154 457 4.3E-72 T 28-03-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CO689_RS05130 4d613cfc19ff37b317e71e07fe771430 827 Pfam PF13244 Domain of unknown function (DUF4040) 663 725 7.5E-20 T 28-03-2018 IPR025383 Domain of unknown function DUF4040 CO689_RS09415 711a56300e66edfedc70f73794fb78fc 285 Pfam PF04536 TPM domain 39 176 6.7E-21 T 28-03-2018 IPR007621 TPM domain CO689_RS09095 6353df975190b41ee86b20312a648692 226 SUPERFAMILY SSF53271 78 225 3.2E-17 T 28-03-2018 IPR029057 Phosphoribosyltransferase-like CO689_RS09095 6353df975190b41ee86b20312a648692 226 Gene3D G3DSA:3.40.50.2020 64 226 2.0E-18 T 28-03-2018 CO689_RS13060 c5a4bb29a03b1bff130049b8026aed3b 128 SUPERFAMILY SSF52821 11 122 3.4E-31 T 28-03-2018 IPR001763 Rhodanese-like domain CO689_RS13060 c5a4bb29a03b1bff130049b8026aed3b 128 Gene3D G3DSA:3.40.250.10 27 128 5.5E-26 T 28-03-2018 IPR001763 Rhodanese-like domain CO689_RS13060 c5a4bb29a03b1bff130049b8026aed3b 128 Pfam PF00581 Rhodanese-like domain 35 121 3.5E-16 T 28-03-2018 IPR001763 Rhodanese-like domain CO689_RS13060 c5a4bb29a03b1bff130049b8026aed3b 128 SMART SM00450 31 126 1.2E-24 T 28-03-2018 IPR001763 Rhodanese-like domain CO689_RS05890 62926ea3dc041559f5744e4452f7d288 683 SUPERFAMILY SSF53623 117 323 3.92E-32 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CO689_RS05890 62926ea3dc041559f5744e4452f7d288 683 Gene3D G3DSA:3.90.190.20 334 480 6.0E-17 T 28-03-2018 CO689_RS05890 62926ea3dc041559f5744e4452f7d288 683 SUPERFAMILY SSF53244 338 456 6.13E-17 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CO689_RS05890 62926ea3dc041559f5744e4452f7d288 683 Gene3D G3DSA:3.40.1190.10 97 323 7.1E-37 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CO689_RS05890 62926ea3dc041559f5744e4452f7d288 683 Pfam PF08245 Mur ligase middle domain 122 305 7.5E-29 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CO689_RS04325 ccbd2ef6d126ef5777bfcec42f909d40 93 Pfam PF14542 GCN5-related N-acetyl-transferase 11 86 7.5E-21 T 28-03-2018 IPR031165 Yjdj-type Gcn5-related N-acetyltransferase CO689_RS04325 ccbd2ef6d126ef5777bfcec42f909d40 93 SUPERFAMILY SSF55729 5 86 1.12E-18 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CO689_RS04325 ccbd2ef6d126ef5777bfcec42f909d40 93 Gene3D G3DSA:3.40.630.30 2 93 6.3E-14 T 28-03-2018 CO689_RS09965 7c0d80339dd7c04fb0524775917cc057 437 Pfam PF13726 Na+-H+ antiporter family 3 89 2.1E-30 T 28-03-2018 IPR032813 Putative Na+/H+ antiporter, N-terminal CO689_RS09965 7c0d80339dd7c04fb0524775917cc057 437 Pfam PF03553 Na+/H+ antiporter family 151 430 1.7E-63 T 28-03-2018 IPR018461 Na+/H+ antiporter, NhaC-like, C-terminal GO:0016021 CO689_RS03565 cc5d99600a0c8a7a5759088f70f0c823 280 Pfam PF01226 Formate/nitrite transporter 22 269 6.9E-47 T 28-03-2018 IPR000292 Formate/nitrite transporter GO:0005215|GO:0006810|GO:0016020 CO689_RS03565 cc5d99600a0c8a7a5759088f70f0c823 280 Gene3D G3DSA:1.20.1080.10 13 280 3.4E-54 T 28-03-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 CO689_RS01130 703a0227bab1ad8d4d3702bad5fb3064 493 SUPERFAMILY SSF51905 1 47 1.49E-12 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CO689_RS01130 703a0227bab1ad8d4d3702bad5fb3064 493 SUPERFAMILY SSF51905 318 487 1.49E-12 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CO689_RS01130 703a0227bab1ad8d4d3702bad5fb3064 493 SUPERFAMILY SSF51905 78 233 1.49E-12 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CO689_RS01130 703a0227bab1ad8d4d3702bad5fb3064 493 Gene3D G3DSA:3.50.50.60 1 188 9.0E-7 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CO689_RS01130 703a0227bab1ad8d4d3702bad5fb3064 493 Gene3D G3DSA:3.50.50.60 189 492 5.3E-8 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CO689_RS01130 703a0227bab1ad8d4d3702bad5fb3064 493 Pfam PF13454 FAD-NAD(P)-binding 4 159 1.7E-29 T 28-03-2018 CO689_RS01890 bdb3eb848176a521337a399330da2fff 520 Pfam PF00939 Sodium:sulfate symporter transmembrane region 35 500 1.5E-93 T 28-03-2018 IPR001898 Solute carrier family 13 GO:0005215|GO:0006814|GO:0016020|GO:0055085 Reactome: R-HSA-433137 CO689_RS01890 bdb3eb848176a521337a399330da2fff 520 TIGRFAM TIGR00785 dass: transporter, divalent anion:Na+ symporter (DASS) family 51 502 1.7E-83 T 28-03-2018 IPR001898 Solute carrier family 13 GO:0005215|GO:0006814|GO:0016020|GO:0055085 Reactome: R-HSA-433137 CO689_RS12585 4b3dc7a9a2dc76457ebbfcf9fb8df301 511 Gene3D G3DSA:1.10.101.10 422 499 6.7E-14 T 28-03-2018 IPR002477 Peptidoglycan binding-like CO689_RS12585 4b3dc7a9a2dc76457ebbfcf9fb8df301 511 SMART SM00228 151 222 5.0E-15 T 28-03-2018 IPR001478 PDZ domain GO:0005515 CO689_RS12585 4b3dc7a9a2dc76457ebbfcf9fb8df301 511 TIGRFAM TIGR00225 prc: C-terminal processing peptidase 103 418 4.3E-102 T 28-03-2018 IPR004447 C-terminal-processing peptidase S41A GO:0006508|GO:0008236 CO689_RS12585 4b3dc7a9a2dc76457ebbfcf9fb8df301 511 SUPERFAMILY SSF52096 240 415 1.49E-67 T 28-03-2018 IPR029045 ClpP/crotonase-like domain CO689_RS12585 4b3dc7a9a2dc76457ebbfcf9fb8df301 511 SUPERFAMILY SSF52096 90 169 1.49E-67 T 28-03-2018 IPR029045 ClpP/crotonase-like domain CO689_RS12585 4b3dc7a9a2dc76457ebbfcf9fb8df301 511 Gene3D G3DSA:2.30.42.10 151 230 2.4E-21 T 28-03-2018 CO689_RS12585 4b3dc7a9a2dc76457ebbfcf9fb8df301 511 SUPERFAMILY SSF50156 122 236 2.32E-21 T 28-03-2018 IPR001478 PDZ domain GO:0005515 CO689_RS12585 4b3dc7a9a2dc76457ebbfcf9fb8df301 511 Pfam PF13180 PDZ domain 152 230 3.1E-15 T 28-03-2018 IPR001478 PDZ domain GO:0005515 CO689_RS12585 4b3dc7a9a2dc76457ebbfcf9fb8df301 511 Pfam PF01471 Putative peptidoglycan binding domain 433 485 8.2E-11 T 28-03-2018 IPR002477 Peptidoglycan binding-like CO689_RS12585 4b3dc7a9a2dc76457ebbfcf9fb8df301 511 Gene3D G3DSA:3.90.226.10 231 421 2.1E-56 T 28-03-2018 CO689_RS12585 4b3dc7a9a2dc76457ebbfcf9fb8df301 511 Pfam PF03572 Peptidase family S41 246 410 1.1E-46 T 28-03-2018 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 CO689_RS12585 4b3dc7a9a2dc76457ebbfcf9fb8df301 511 SUPERFAMILY SSF47090 421 488 1.26E-12 T 28-03-2018 IPR002477 Peptidoglycan binding-like CO689_RS12585 4b3dc7a9a2dc76457ebbfcf9fb8df301 511 SMART SM00245 222 411 2.9E-54 T 28-03-2018 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 CO689_RS12585 4b3dc7a9a2dc76457ebbfcf9fb8df301 511 Gene3D G3DSA:3.30.750.44 52 150 8.0E-19 T 28-03-2018 CO689_RS03765 c44bfd964b6b10d09a6b1cd1f5be0624 214 Gene3D G3DSA:2.40.50.100 102 200 0.059 T 28-03-2018 CO689_RS03765 c44bfd964b6b10d09a6b1cd1f5be0624 214 Pfam PF13437 HlyD family secretion protein 90 198 7.1E-14 T 28-03-2018 CO689_RS03765 c44bfd964b6b10d09a6b1cd1f5be0624 214 Gene3D G3DSA:2.40.50.100 27 60 0.15 T 28-03-2018 CO689_RS03765 c44bfd964b6b10d09a6b1cd1f5be0624 214 Gene3D G3DSA:2.40.50.100 61 101 5.1E-7 T 28-03-2018 CO689_RS08145 b7f879362453e7c5c1effce2225d54e3 268 Gene3D G3DSA:3.30.70.1410 107 190 8.7E-27 T 28-03-2018 CO689_RS08145 b7f879362453e7c5c1effce2225d54e3 268 Pfam PF05116 Sucrose-6F-phosphate phosphohydrolase 3 239 8.0E-14 T 28-03-2018 IPR006380 Sucrose-phosphatase-like, N-terminal CO689_RS08145 b7f879362453e7c5c1effce2225d54e3 268 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 5 235 1.7E-26 T 28-03-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 CO689_RS08145 b7f879362453e7c5c1effce2225d54e3 268 SUPERFAMILY SSF56784 1 241 2.1E-21 T 28-03-2018 IPR023214 HAD-like domain CO689_RS13250 12646d369f54062ace6cd335b0d51ac1 153 Gene3D G3DSA:3.40.390.30 1 153 3.6E-52 T 28-03-2018 IPR023091 Metalloprotease catalytic domain, predicted GO:0004222 CO689_RS13250 12646d369f54062ace6cd335b0d51ac1 153 TIGRFAM TIGR00043 TIGR00043: rRNA maturation RNase YbeY 39 149 3.7E-43 T 28-03-2018 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 CO689_RS13250 12646d369f54062ace6cd335b0d51ac1 153 ProSitePatterns PS01306 Uncharacterized protein family UPF0054 signature. 118 128 - T 28-03-2018 IPR020549 Endoribonuclease YbeY, conserved site CO689_RS13250 12646d369f54062ace6cd335b0d51ac1 153 SUPERFAMILY SSF55486 2 152 1.49E-46 T 28-03-2018 CO689_RS13250 12646d369f54062ace6cd335b0d51ac1 153 Pfam PF02130 Uncharacterized protein family UPF0054 13 147 7.6E-48 T 28-03-2018 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 CO689_RS13250 12646d369f54062ace6cd335b0d51ac1 153 Hamap MF_00009 Endoribonuclease YbeY [ybeY]. 1 152 24.664 T 28-03-2018 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 CO689_RS12450 e066ccb9a3e8f22170ca4ef415056fdc 329 SUPERFAMILY SSF51735 1 152 8.81E-41 T 28-03-2018 IPR016040 NAD(P)-binding domain CO689_RS12450 e066ccb9a3e8f22170ca4ef415056fdc 329 Hamap MF_02121 Aspartate-semialdehyde dehydrogenase [asd]. 1 323 33.825 T 28-03-2018 IPR012080 Aspartate-semialdehyde dehydrogenase GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 CO689_RS12450 e066ccb9a3e8f22170ca4ef415056fdc 329 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 3 113 1.0E-26 T 28-03-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 CO689_RS12450 e066ccb9a3e8f22170ca4ef415056fdc 329 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 135 309 7.6E-49 T 28-03-2018 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0003942|GO:0005737|GO:0008652|GO:0016620|GO:0046983|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 CO689_RS12450 e066ccb9a3e8f22170ca4ef415056fdc 329 SMART SM00859 3 118 2.9E-26 T 28-03-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 CO689_RS12450 e066ccb9a3e8f22170ca4ef415056fdc 329 SUPERFAMILY SSF55347 125 310 6.03E-68 T 28-03-2018 CO689_RS12450 e066ccb9a3e8f22170ca4ef415056fdc 329 Gene3D G3DSA:3.30.360.10 137 306 1.4E-62 T 28-03-2018 CO689_RS12450 e066ccb9a3e8f22170ca4ef415056fdc 329 PIRSF PIRSF000148 1 328 1.8E-112 T 28-03-2018 CO689_RS12450 e066ccb9a3e8f22170ca4ef415056fdc 329 TIGRFAM TIGR01296 asd_B: aspartate-semialdehyde dehydrogenase 4 322 4.8E-114 T 28-03-2018 IPR005986 Aspartate-semialdehyde dehydrogenase, beta-type GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 CO689_RS12450 e066ccb9a3e8f22170ca4ef415056fdc 329 Gene3D G3DSA:3.40.50.720 1 136 4.2E-26 T 28-03-2018 CO689_RS05135 127711047a281fa08778eceb31f2efc2 186 SUPERFAMILY SSF56349 7 175 6.47E-33 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CO689_RS05135 127711047a281fa08778eceb31f2efc2 186 Pfam PF00589 Phage integrase family 10 170 2.8E-23 T 28-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 CO689_RS05135 127711047a281fa08778eceb31f2efc2 186 Gene3D G3DSA:1.10.443.10 7 177 3.9E-30 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 CO689_RS00945 2f7260e1880e3f1eddecaaaea4059950 301 Gene3D G3DSA:1.10.3810.10 76 290 1.9E-56 T 28-03-2018 IPR001264 Glycosyl transferase, family 51 CO689_RS00945 2f7260e1880e3f1eddecaaaea4059950 301 SUPERFAMILY SSF53955 78 296 3.09E-56 T 28-03-2018 IPR023346 Lysozyme-like domain CO689_RS00945 2f7260e1880e3f1eddecaaaea4059950 301 Pfam PF00912 Transglycosylase 86 273 1.8E-50 T 28-03-2018 IPR001264 Glycosyl transferase, family 51 CO689_RS06265 65ac88f4e8293650e94db626d8b34bfb 440 SUPERFAMILY SSF53383 35 438 2.69E-123 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CO689_RS06265 65ac88f4e8293650e94db626d8b34bfb 440 PIRSF PIRSF000521 132 440 1.9E-46 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CO689_RS06265 65ac88f4e8293650e94db626d8b34bfb 440 PIRSF PIRSF000521 32 138 6.2E-7 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CO689_RS06265 65ac88f4e8293650e94db626d8b34bfb 440 Pfam PF00202 Aminotransferase class-III 35 436 1.2E-129 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CO689_RS06265 65ac88f4e8293650e94db626d8b34bfb 440 TIGRFAM TIGR00700 GABAtrnsam: 4-aminobutyrate transaminase 21 437 1.2E-193 T 28-03-2018 IPR004632 4-aminobutyrate aminotransferase, bacterial GO:0003867|GO:0009448 CO689_RS06265 65ac88f4e8293650e94db626d8b34bfb 440 Gene3D G3DSA:3.90.1150.10 325 440 3.0E-27 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CO689_RS06265 65ac88f4e8293650e94db626d8b34bfb 440 Gene3D G3DSA:3.40.640.10 201 324 2.1E-43 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CO689_RS06265 65ac88f4e8293650e94db626d8b34bfb 440 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 253 290 - T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CO689_RS06265 65ac88f4e8293650e94db626d8b34bfb 440 Gene3D G3DSA:3.90.1150.10 4 200 1.7E-37 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CO689_RS13545 e97767550f624edbf0300b525c6e4126 338 SMART SM00382 52 183 6.4E-13 T 28-03-2018 IPR003593 AAA+ ATPase domain CO689_RS13545 e97767550f624edbf0300b525c6e4126 338 Hamap MF_00016 Holliday junction ATP-dependent DNA helicase RuvB [ruvB]. 1 338 166.794 T 28-03-2018 IPR004605 DNA helicase, Holliday junction RuvB type GO:0003677|GO:0005524|GO:0006281|GO:0006310|GO:0009378 CO689_RS13545 e97767550f624edbf0300b525c6e4126 338 SUPERFAMILY SSF52540 21 253 3.02E-53 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CO689_RS13545 e97767550f624edbf0300b525c6e4126 338 Gene3D G3DSA:1.10.8.60 185 255 4.7E-30 T 28-03-2018 CO689_RS13545 e97767550f624edbf0300b525c6e4126 338 TIGRFAM TIGR00635 ruvB: Holliday junction DNA helicase RuvB 25 327 1.3E-142 T 28-03-2018 IPR004605 DNA helicase, Holliday junction RuvB type GO:0003677|GO:0005524|GO:0006281|GO:0006310|GO:0009378 CO689_RS13545 e97767550f624edbf0300b525c6e4126 338 Pfam PF05491 Holliday junction DNA helicase ruvB C-terminus 254 327 1.1E-33 T 28-03-2018 IPR008823 DNA helicase, Holliday junction RuvB type, C-terminal GO:0003677|GO:0006281|GO:0006310|GO:0009378 CO689_RS13545 e97767550f624edbf0300b525c6e4126 338 Pfam PF05496 Holliday junction DNA helicase ruvB N-terminus 4 236 8.5E-115 T 28-03-2018 IPR008824 Holliday junction DNA helicase ruvB, N-terminal GO:0006281|GO:0006310|GO:0009378 CO689_RS13545 e97767550f624edbf0300b525c6e4126 338 Gene3D G3DSA:3.40.50.300 19 182 1.2E-27 T 28-03-2018 CO689_RS13545 e97767550f624edbf0300b525c6e4126 338 SUPERFAMILY SSF46785 258 329 4.44E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS13545 e97767550f624edbf0300b525c6e4126 338 ProDom PD005323 DNA HELICASE HOLLIDAY JUNCTION RUVB NUCLEOTIDE-BINDING ATP-BINDING SOS RECOMBINATION RESPONSE 251 332 5.0E-37 T 28-03-2018 IPR008823 DNA helicase, Holliday junction RuvB type, C-terminal GO:0003677|GO:0006281|GO:0006310|GO:0009378 CO689_RS13545 e97767550f624edbf0300b525c6e4126 338 Gene3D G3DSA:1.10.10.10 258 328 1.7E-33 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS06820 320424e0005d5f7f539d16e807f3a33e 244 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 242 1.6E-65 T 28-03-2018 CO689_RS06820 320424e0005d5f7f539d16e807f3a33e 244 Gene3D G3DSA:3.40.50.720 1 244 6.8E-66 T 28-03-2018 CO689_RS06820 320424e0005d5f7f539d16e807f3a33e 244 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 132 140 4.9E-12 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CO689_RS06820 320424e0005d5f7f539d16e807f3a33e 244 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 79 90 4.9E-12 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CO689_RS06820 320424e0005d5f7f539d16e807f3a33e 244 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 150 169 4.9E-12 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CO689_RS06820 320424e0005d5f7f539d16e807f3a33e 244 SUPERFAMILY SSF51735 5 243 2.89E-78 T 28-03-2018 IPR016040 NAD(P)-binding domain CO689_RS06820 320424e0005d5f7f539d16e807f3a33e 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 150 169 1.7E-41 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CO689_RS06820 320424e0005d5f7f539d16e807f3a33e 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 126 142 1.7E-41 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CO689_RS06820 320424e0005d5f7f539d16e807f3a33e 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 205 225 1.7E-41 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CO689_RS06820 320424e0005d5f7f539d16e807f3a33e 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 79 90 1.7E-41 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CO689_RS06820 320424e0005d5f7f539d16e807f3a33e 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 171 188 1.7E-41 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CO689_RS06820 320424e0005d5f7f539d16e807f3a33e 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 1.7E-41 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CO689_RS06890 9355376af2d899137714ac964a30599b 288 SUPERFAMILY SSF53448 1 268 6.64E-70 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CO689_RS06890 9355376af2d899137714ac964a30599b 288 TIGRFAM TIGR01099 galU: UTP--glucose-1-phosphate uridylyltransferase 4 264 1.1E-117 T 28-03-2018 IPR005771 UTP--glucose-1-phosphate uridylyltransferase, bacterial/archaeal-type GO:0003983|GO:0006011 KEGG: 00040+2.7.7.9|KEGG: 00052+2.7.7.9|KEGG: 00500+2.7.7.9|KEGG: 00520+2.7.7.9|MetaCyc: PWY-3801|MetaCyc: PWY-6527|MetaCyc: PWY-7238|MetaCyc: PWY-7343|MetaCyc: PWY-7817 CO689_RS06890 9355376af2d899137714ac964a30599b 288 Pfam PF00483 Nucleotidyl transferase 6 261 1.9E-36 T 28-03-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 CO689_RS06890 9355376af2d899137714ac964a30599b 288 Gene3D G3DSA:3.90.550.10 1 287 3.5E-63 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CO689_RS08550 b12912e1c74850764a140520ac17c563 342 SUPERFAMILY SSF53474 46 319 1.53E-45 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CO689_RS08550 b12912e1c74850764a140520ac17c563 342 Gene3D G3DSA:3.40.50.1820 54 319 8.1E-35 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CO689_RS08550 b12912e1c74850764a140520ac17c563 342 Pfam PF07859 alpha/beta hydrolase fold 84 291 1.2E-26 T 28-03-2018 IPR013094 Alpha/beta hydrolase fold-3 GO:0008152|GO:0016787 CO689_RS10275 b41ff16fb44510dcb1b656cd55e6261f 460 TIGRFAM TIGR00400 mgtE: magnesium transporter 22 457 5.1E-124 T 28-03-2018 IPR006669 Magnesium transporter MgtE GO:0015095|GO:0015693|GO:0016020 CO689_RS10275 b41ff16fb44510dcb1b656cd55e6261f 460 SUPERFAMILY SSF54631 143 280 3.41E-33 T 28-03-2018 CO689_RS10275 b41ff16fb44510dcb1b656cd55e6261f 460 Pfam PF00571 CBS domain 208 263 3.6E-9 T 28-03-2018 IPR000644 CBS domain CO689_RS10275 b41ff16fb44510dcb1b656cd55e6261f 460 Pfam PF00571 CBS domain 145 202 2.0E-7 T 28-03-2018 IPR000644 CBS domain CO689_RS10275 b41ff16fb44510dcb1b656cd55e6261f 460 Gene3D G3DSA:1.10.357.20 284 459 2.2E-41 T 28-03-2018 IPR006667 SLC41 divalent cation transporters, integral membrane domain GO:0006812|GO:0008324 CO689_RS10275 b41ff16fb44510dcb1b656cd55e6261f 460 Gene3D G3DSA:3.10.580.10 134 273 8.6E-23 T 28-03-2018 CO689_RS10275 b41ff16fb44510dcb1b656cd55e6261f 460 SMART SM00924 39 144 8.0E-25 T 28-03-2018 IPR006668 Magnesium transporter, MgtE intracellular domain CO689_RS10275 b41ff16fb44510dcb1b656cd55e6261f 460 Pfam PF01769 Divalent cation transporter 328 449 1.2E-27 T 28-03-2018 IPR006667 SLC41 divalent cation transporters, integral membrane domain GO:0006812|GO:0008324 CO689_RS10275 b41ff16fb44510dcb1b656cd55e6261f 460 Gene3D G3DSA:1.25.60.10 9 133 2.9E-21 T 28-03-2018 CO689_RS10275 b41ff16fb44510dcb1b656cd55e6261f 460 SUPERFAMILY SSF158791 18 141 6.67E-26 T 28-03-2018 CO689_RS10275 b41ff16fb44510dcb1b656cd55e6261f 460 SUPERFAMILY SSF161093 284 456 2.75E-51 T 28-03-2018 CO689_RS10275 b41ff16fb44510dcb1b656cd55e6261f 460 SMART SM00116 215 263 7.8E-7 T 28-03-2018 IPR000644 CBS domain CO689_RS10275 b41ff16fb44510dcb1b656cd55e6261f 460 SMART SM00116 151 204 2.8 T 28-03-2018 IPR000644 CBS domain CO689_RS10275 b41ff16fb44510dcb1b656cd55e6261f 460 Pfam PF03448 MgtE intracellular N domain 39 142 1.9E-21 T 28-03-2018 IPR006668 Magnesium transporter, MgtE intracellular domain CO689_RS05095 88d00a2bf926db9432d601a08c7bd500 330 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 112 298 9.9E-50 T 28-03-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 CO689_RS05095 88d00a2bf926db9432d601a08c7bd500 330 ProSitePatterns PS00670 D-isomer specific 2-hydroxyacid dehydrogenases signature 2. 195 217 - T 28-03-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site CO689_RS05095 88d00a2bf926db9432d601a08c7bd500 330 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 149 176 - T 28-03-2018 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 CO689_RS05095 88d00a2bf926db9432d601a08c7bd500 330 SUPERFAMILY SSF52283 1 136 2.13E-35 T 28-03-2018 CO689_RS05095 88d00a2bf926db9432d601a08c7bd500 330 Gene3D G3DSA:3.40.50.720 118 301 1.2E-45 T 28-03-2018 CO689_RS05095 88d00a2bf926db9432d601a08c7bd500 330 Gene3D G3DSA:3.40.50.720 2 117 6.9E-21 T 28-03-2018 CO689_RS05095 88d00a2bf926db9432d601a08c7bd500 330 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 15 330 2.1E-23 T 28-03-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 CO689_RS05095 88d00a2bf926db9432d601a08c7bd500 330 SUPERFAMILY SSF51735 103 299 3.89E-50 T 28-03-2018 IPR016040 NAD(P)-binding domain CO689_RS05095 88d00a2bf926db9432d601a08c7bd500 330 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 224 240 - T 28-03-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site CO689_RS11170 73b6c304e4941d9db3e3cd7d5492abd8 216 Pfam PF07553 Host cell surface-exposed lipoprotein 168 215 3.3E-25 T 28-03-2018 IPR011434 Domain of unknown function DUF1535 CO689_RS11170 73b6c304e4941d9db3e3cd7d5492abd8 216 Pfam PF07553 Host cell surface-exposed lipoprotein 121 165 9.5E-24 T 28-03-2018 IPR011434 Domain of unknown function DUF1535 CO689_RS12630 a23d64c9e1e95a1b5d53082056df8265 372 Pfam PF13646 HEAT repeats 237 316 1.4E-9 T 28-03-2018 CO689_RS12630 a23d64c9e1e95a1b5d53082056df8265 372 SUPERFAMILY SSF110836 1 85 4.05E-24 T 28-03-2018 IPR014824 Scaffold protein Nfu/NifU, N-terminal CO689_RS12630 a23d64c9e1e95a1b5d53082056df8265 372 SMART SM00567 E-Z type HEAT repeats 309 338 93.0 T 28-03-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 CO689_RS12630 a23d64c9e1e95a1b5d53082056df8265 372 SMART SM00567 E-Z type HEAT repeats 247 276 800.0 T 28-03-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 CO689_RS12630 a23d64c9e1e95a1b5d53082056df8265 372 SMART SM00567 E-Z type HEAT repeats 278 307 3.9 T 28-03-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 CO689_RS12630 a23d64c9e1e95a1b5d53082056df8265 372 Gene3D G3DSA:1.25.40.70 290 356 3.8E-5 T 28-03-2018 CO689_RS12630 a23d64c9e1e95a1b5d53082056df8265 372 Gene3D G3DSA:1.25.40.70 164 289 7.9E-9 T 28-03-2018 CO689_RS12630 a23d64c9e1e95a1b5d53082056df8265 372 SMART SM00932 4 89 2.2E-22 T 28-03-2018 IPR014824 Scaffold protein Nfu/NifU, N-terminal CO689_RS12630 a23d64c9e1e95a1b5d53082056df8265 372 Pfam PF08712 Scaffold protein Nfu/NifU N terminal 4 85 2.7E-19 T 28-03-2018 IPR014824 Scaffold protein Nfu/NifU, N-terminal CO689_RS12630 a23d64c9e1e95a1b5d53082056df8265 372 Gene3D G3DSA:3.30.1370.70 2 88 2.9E-19 T 28-03-2018 IPR014824 Scaffold protein Nfu/NifU, N-terminal CO689_RS12630 a23d64c9e1e95a1b5d53082056df8265 372 Pfam PF13769 Virulence factor 109 187 1.0E-26 T 28-03-2018 IPR025989 Virulence factor domain CO689_RS12630 a23d64c9e1e95a1b5d53082056df8265 372 SUPERFAMILY SSF48371 232 368 5.12E-21 T 28-03-2018 IPR016024 Armadillo-type fold GO:0005488 CO689_RS12085 8d6345e50f16c99d4c1a349a233d019e 458 PIRSF PIRSF000726 1 454 3.9E-82 T 28-03-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 CO689_RS12085 8d6345e50f16c99d4c1a349a233d019e 458 SUPERFAMILY SSF55021 297 367 3.52E-13 T 28-03-2018 CO689_RS12085 8d6345e50f16c99d4c1a349a233d019e 458 SUPERFAMILY SSF55021 373 446 5.99E-18 T 28-03-2018 CO689_RS12085 8d6345e50f16c99d4c1a349a233d019e 458 SUPERFAMILY SSF53633 1 289 3.93E-66 T 28-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase CO689_RS12085 8d6345e50f16c99d4c1a349a233d019e 458 TIGRFAM TIGR00657 asp_kinases: aspartate kinase 3 445 7.3E-84 T 28-03-2018 IPR001341 Aspartate kinase domain GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 CO689_RS12085 8d6345e50f16c99d4c1a349a233d019e 458 Gene3D G3DSA:3.30.70.260 371 448 1.0E-16 T 28-03-2018 CO689_RS12085 8d6345e50f16c99d4c1a349a233d019e 458 Gene3D G3DSA:3.40.1160.10 1 281 1.4E-52 T 28-03-2018 CO689_RS12085 8d6345e50f16c99d4c1a349a233d019e 458 ProSitePatterns PS00324 Aspartokinase signature. 3 11 - T 28-03-2018 IPR018042 Aspartate kinase, conserved site GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 CO689_RS12085 8d6345e50f16c99d4c1a349a233d019e 458 Pfam PF00696 Amino acid kinase family 2 276 6.6E-42 T 28-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase CO689_RS12085 8d6345e50f16c99d4c1a349a233d019e 458 Gene3D G3DSA:3.30.70.260 282 370 4.8E-21 T 28-03-2018 CO689_RS03340 8bf45e40c0380617d7068d4599348a53 330 Gene3D G3DSA:3.40.50.720 1 164 2.1E-34 T 28-03-2018 CO689_RS03340 8bf45e40c0380617d7068d4599348a53 330 TIGRFAM TIGR01179 galE: UDP-glucose 4-epimerase GalE 3 326 2.4E-129 T 28-03-2018 IPR005886 UDP-glucose 4-epimerase GO:0003978|GO:0006012 KEGG: 00052+5.1.3.2|KEGG: 00520+5.1.3.2|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6397|MetaCyc: PWY-6527|MetaCyc: PWY-7328|MetaCyc: PWY-7344|Reactome: R-HSA-70370 CO689_RS03340 8bf45e40c0380617d7068d4599348a53 330 SUPERFAMILY SSF51735 1 328 1.91E-95 T 28-03-2018 IPR016040 NAD(P)-binding domain CO689_RS03340 8bf45e40c0380617d7068d4599348a53 330 Gene3D G3DSA:3.90.25.10 165 330 6.0E-42 T 28-03-2018 CO689_RS03340 8bf45e40c0380617d7068d4599348a53 330 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 252 1.4E-58 T 28-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 CO689_RS13100 b0fde5c1e8be0bdebef21518c8a9a7ef 109 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 14 35 3.9E-4 T 28-03-2018 IPR012902 Prokaryotic N-terminal methylation site CO689_RS13100 b0fde5c1e8be0bdebef21518c8a9a7ef 109 PIRSF PIRSF029928 1 109 7.6E-38 T 28-03-2018 IPR016940 ComG operon protein C GO:0030420 CO689_RS13100 b0fde5c1e8be0bdebef21518c8a9a7ef 109 SUPERFAMILY SSF54523 16 77 2.51E-10 T 28-03-2018 CO689_RS13100 b0fde5c1e8be0bdebef21518c8a9a7ef 109 Gene3D G3DSA:3.30.700.10 16 109 1.4E-8 T 28-03-2018 CO689_RS06380 dbf250c5cc769eb8a9efdd49be64cd55 206 SUPERFAMILY SSF55469 3 203 2.36E-55 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CO689_RS06380 dbf250c5cc769eb8a9efdd49be64cd55 206 Pfam PF00881 Nitroreductase family 9 186 1.3E-25 T 28-03-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 CO689_RS06380 dbf250c5cc769eb8a9efdd49be64cd55 206 Gene3D G3DSA:3.40.109.10 1 206 6.3E-42 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CO689_RS04405 328239f0aca110fe901757147636d66a 132 SUPERFAMILY SSF54637 10 130 3.63E-25 T 28-03-2018 IPR029069 HotDog domain CO689_RS04405 328239f0aca110fe901757147636d66a 132 Gene3D G3DSA:3.10.129.10 7 131 1.5E-19 T 28-03-2018 CO689_RS04405 328239f0aca110fe901757147636d66a 132 Pfam PF13279 Thioesterase-like superfamily 19 129 4.3E-9 T 28-03-2018 CO689_RS11025 2a2a024beabc8925c063e5cf9f57e5cb 380 Hamap MF_01539 UPF0348 protein . 2 376 35.659 T 28-03-2018 IPR008513 Uncharacterised protein family UPF0348 CO689_RS11025 2a2a024beabc8925c063e5cf9f57e5cb 380 SUPERFAMILY SSF52374 176 221 1.06E-17 T 28-03-2018 CO689_RS11025 2a2a024beabc8925c063e5cf9f57e5cb 380 SUPERFAMILY SSF52374 1 125 1.06E-17 T 28-03-2018 CO689_RS11025 2a2a024beabc8925c063e5cf9f57e5cb 380 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 5 42 2.9E-7 T 28-03-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 CO689_RS11025 2a2a024beabc8925c063e5cf9f57e5cb 380 Gene3D G3DSA:3.40.50.620 1 228 1.4E-47 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CO689_RS11025 2a2a024beabc8925c063e5cf9f57e5cb 380 Pfam PF05636 HIGH Nucleotidyl Transferase 1 366 1.3E-117 T 28-03-2018 IPR008513 Uncharacterised protein family UPF0348 CO689_RS03605 a365b1af2929606044eb00cc2f3f9f75 435 Pfam PF03553 Na+/H+ antiporter family 25 212 2.5E-13 T 28-03-2018 IPR018461 Na+/H+ antiporter, NhaC-like, C-terminal GO:0016021 CO689_RS03605 a365b1af2929606044eb00cc2f3f9f75 435 Pfam PF03553 Na+/H+ antiporter family 238 423 1.4E-7 T 28-03-2018 IPR018461 Na+/H+ antiporter, NhaC-like, C-terminal GO:0016021 CO689_RS13055 8154073247d634e6bcc7f2a24060beb5 276 SUPERFAMILY SSF55681 4 276 7.13E-66 T 28-03-2018 CO689_RS13055 8154073247d634e6bcc7f2a24060beb5 276 Hamap MF_02118 Octanoyltransferase LipM [lipM]. 2 276 66.759 T 28-03-2018 IPR024898 Octanoyltransferase LipM GO:0009107|GO:0009249|GO:0016415 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382 CO689_RS13055 8154073247d634e6bcc7f2a24060beb5 276 Gene3D G3DSA:3.30.930.10 2 276 1.6E-59 T 28-03-2018 CO689_RS13055 8154073247d634e6bcc7f2a24060beb5 276 Pfam PF03099 Biotin/lipoate A/B protein ligase family 53 188 6.8E-27 T 28-03-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 CO689_RS10290 6cff8089113f26b05731938820de8f1c 414 Gene3D G3DSA:1.20.1250.20 207 401 5.5E-29 T 28-03-2018 CO689_RS10290 6cff8089113f26b05731938820de8f1c 414 Pfam PF07690 Major Facilitator Superfamily 22 277 1.6E-40 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CO689_RS10290 6cff8089113f26b05731938820de8f1c 414 Gene3D G3DSA:1.20.1250.20 4 206 1.0E-39 T 28-03-2018 CO689_RS10290 6cff8089113f26b05731938820de8f1c 414 SUPERFAMILY SSF103473 7 400 1.31E-85 T 28-03-2018 IPR020846 Major facilitator superfamily domain CO689_RS03305 e24628f0d2626ee0f1e5df93c317a873 159 Pfam PF01967 MoaC family 15 151 2.1E-52 T 28-03-2018 IPR002820 Molybdopterin cofactor biosynthesis C (MoaC) domain GO:0006777 Reactome: R-HSA-947581 CO689_RS03305 e24628f0d2626ee0f1e5df93c317a873 159 Hamap MF_01224_B Cyclic pyranopterin monophosphate synthase accessory protein [moaC]. 2 159 35.079 T 28-03-2018 IPR023045 Molybdenum cofactor biosynthesis C GO:0006777 Reactome: R-HSA-947581 CO689_RS03305 e24628f0d2626ee0f1e5df93c317a873 159 TIGRFAM TIGR00581 moaC: molybdenum cofactor biosynthesis protein C 4 153 2.3E-59 T 28-03-2018 IPR023045 Molybdenum cofactor biosynthesis C GO:0006777 Reactome: R-HSA-947581 CO689_RS03305 e24628f0d2626ee0f1e5df93c317a873 159 SUPERFAMILY SSF55040 11 156 4.97E-56 T 28-03-2018 IPR002820 Molybdopterin cofactor biosynthesis C (MoaC) domain GO:0006777 Reactome: R-HSA-947581 CO689_RS03305 e24628f0d2626ee0f1e5df93c317a873 159 Gene3D G3DSA:3.30.70.640 2 159 1.8E-66 T 28-03-2018 IPR002820 Molybdopterin cofactor biosynthesis C (MoaC) domain GO:0006777 Reactome: R-HSA-947581 CO689_RS10465 85d2249f777a26ae0a4fbbb7180469a9 72 Pfam PF08858 IDEAL domain 27 63 4.9E-14 T 28-03-2018 IPR014957 IDEAL domain CO689_RS10465 85d2249f777a26ae0a4fbbb7180469a9 72 SMART SM00914 27 63 1.6E-9 T 28-03-2018 IPR014957 IDEAL domain CO689_RS00800 8210839536203640eed289af10721a1e 32 Pfam PF17210 SdrD B-like domain 1 29 2.1E-7 T 28-03-2018 IPR033764 SD-repeat containing protein, B domain CO689_RS00800 8210839536203640eed289af10721a1e 32 Gene3D G3DSA:2.60.40.10 1 30 1.0E-7 T 28-03-2018 IPR013783 Immunoglobulin-like fold CO689_RS00800 8210839536203640eed289af10721a1e 32 SUPERFAMILY SSF49478 1 29 2.51E-6 T 28-03-2018 CO689_RS02370 63154c3d0497556d60950ab1dd103d42 170 SUPERFAMILY SSF55729 1 159 6.93E-37 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CO689_RS02370 63154c3d0497556d60950ab1dd103d42 170 Gene3D G3DSA:3.40.630.30 1 168 1.4E-33 T 28-03-2018 CO689_RS02370 63154c3d0497556d60950ab1dd103d42 170 Pfam PF13673 Acetyltransferase (GNAT) domain 30 151 7.5E-18 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CO689_RS02875 24b206ddae90fccdec3ea38f1d552262 655 Pfam PF06276 Ferric iron reductase FhuF-like transporter 470 643 3.7E-28 T 28-03-2018 IPR022770 Ferric iron reductase FhuF domain CO689_RS02875 24b206ddae90fccdec3ea38f1d552262 655 Pfam PF04183 IucA / IucC family 196 432 2.3E-58 T 28-03-2018 IPR007310 Aerobactin siderophore biosynthesis, IucA/IucC, N-terminal GO:0015343|GO:0019290 CO689_RS12295 66b4add23350db06d05164d11b70695b 338 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 97 241 4.6E-31 T 28-03-2018 IPR004474 Cell envelope-related transcriptional attenuator domain CO689_RS12295 66b4add23350db06d05164d11b70695b 338 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 97 241 1.8E-46 T 28-03-2018 IPR004474 Cell envelope-related transcriptional attenuator domain CO689_RS11990 01d3cbc55507f7fa6045df33d671f38f 311 Gene3D G3DSA:3.40.50.1820 2 310 1.4E-31 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CO689_RS11990 01d3cbc55507f7fa6045df33d671f38f 311 Pfam PF12146 Serine aminopeptidase, S33 29 287 1.3E-53 T 28-03-2018 IPR022742 Serine aminopeptidase, S33 CO689_RS11990 01d3cbc55507f7fa6045df33d671f38f 311 SUPERFAMILY SSF53474 7 301 2.87E-34 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CO689_RS07625 4db7120716cedee7f6e88f0b7f525c43 300 Gene3D G3DSA:3.40.190.10 1 256 5.1E-4 T 28-03-2018 CO689_RS07625 4db7120716cedee7f6e88f0b7f525c43 300 Pfam PF07901 Protein of unknown function (DUF1672) 32 288 1.3E-91 T 28-03-2018 IPR012873 Protein of unknown function DUF1672 CO689_RS04080 94b09ec8f20b52156a385da77a50b32f 461 Pfam PF00324 Amino acid permease 13 449 2.3E-96 T 28-03-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0006810|GO:0016020|GO:0055085 CO689_RS04080 94b09ec8f20b52156a385da77a50b32f 461 PIRSF PIRSF006060 2 461 9.3E-69 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CO689_RS10070 c48afa5a25abd40698bee555f6f4f626 457 Gene3D G3DSA:1.20.200.10 109 376 1.4E-92 T 28-03-2018 CO689_RS10070 c48afa5a25abd40698bee555f6f4f626 457 Hamap MF_00006 Argininosuccinate lyase [argH]. 4 455 43.225 T 28-03-2018 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CO689_RS10070 c48afa5a25abd40698bee555f6f4f626 457 PRINTS PR00145 Argininosuccinate lyase family signature 277 293 1.0E-66 T 28-03-2018 CO689_RS10070 c48afa5a25abd40698bee555f6f4f626 457 PRINTS PR00145 Argininosuccinate lyase family signature 195 211 1.0E-66 T 28-03-2018 CO689_RS10070 c48afa5a25abd40698bee555f6f4f626 457 PRINTS PR00145 Argininosuccinate lyase family signature 312 331 1.0E-66 T 28-03-2018 CO689_RS10070 c48afa5a25abd40698bee555f6f4f626 457 PRINTS PR00145 Argininosuccinate lyase family signature 144 164 1.0E-66 T 28-03-2018 CO689_RS10070 c48afa5a25abd40698bee555f6f4f626 457 PRINTS PR00145 Argininosuccinate lyase family signature 103 125 1.0E-66 T 28-03-2018 CO689_RS10070 c48afa5a25abd40698bee555f6f4f626 457 PRINTS PR00145 Argininosuccinate lyase family signature 233 257 1.0E-66 T 28-03-2018 CO689_RS10070 c48afa5a25abd40698bee555f6f4f626 457 TIGRFAM TIGR00838 argH: argininosuccinate lyase 6 455 4.7E-197 T 28-03-2018 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CO689_RS10070 c48afa5a25abd40698bee555f6f4f626 457 Pfam PF00206 Lyase 8 302 3.5E-77 T 28-03-2018 IPR022761 Fumarate lyase, N-terminal CO689_RS10070 c48afa5a25abd40698bee555f6f4f626 457 ProSitePatterns PS00163 Fumarate lyases signature. 277 286 - T 28-03-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 CO689_RS10070 c48afa5a25abd40698bee555f6f4f626 457 Gene3D G3DSA:1.10.40.30 377 434 4.9E-22 T 28-03-2018 CO689_RS10070 c48afa5a25abd40698bee555f6f4f626 457 Pfam PF14698 Argininosuccinate lyase C-terminal 365 432 2.1E-23 T 28-03-2018 IPR029419 Argininosuccinate lyase, C-terminal KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CO689_RS10070 c48afa5a25abd40698bee555f6f4f626 457 Gene3D G3DSA:1.10.275.10 4 108 1.4E-39 T 28-03-2018 IPR024083 Fumarase/histidase, N-terminal CO689_RS10070 c48afa5a25abd40698bee555f6f4f626 457 SUPERFAMILY SSF48557 6 457 1.26E-150 T 28-03-2018 IPR008948 L-Aspartase-like GO:0003824 CO689_RS10070 c48afa5a25abd40698bee555f6f4f626 457 PRINTS PR00149 Fumarate lyase superfamily signature 233 260 1.2E-30 T 28-03-2018 IPR000362 Fumarate lyase family CO689_RS10070 c48afa5a25abd40698bee555f6f4f626 457 PRINTS PR00149 Fumarate lyase superfamily signature 277 293 1.2E-30 T 28-03-2018 IPR000362 Fumarate lyase family CO689_RS10070 c48afa5a25abd40698bee555f6f4f626 457 PRINTS PR00149 Fumarate lyase superfamily signature 104 122 1.2E-30 T 28-03-2018 IPR000362 Fumarate lyase family CO689_RS10070 c48afa5a25abd40698bee555f6f4f626 457 PRINTS PR00149 Fumarate lyase superfamily signature 149 167 1.2E-30 T 28-03-2018 IPR000362 Fumarate lyase family CO689_RS12170 6480050cba445f1ee19e47faef84e603 207 Hamap MF_00015 LexA repressor [lexA]. 3 207 35.431 T 28-03-2018 IPR006200 Transcription regulator LexA GO:0004252|GO:0009432|GO:0045892 CO689_RS12170 6480050cba445f1ee19e47faef84e603 207 SUPERFAMILY SSF51306 83 205 2.27E-35 T 28-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C CO689_RS12170 6480050cba445f1ee19e47faef84e603 207 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 133 144 1.7E-10 T 28-03-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 CO689_RS12170 6480050cba445f1ee19e47faef84e603 207 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 122 132 1.7E-10 T 28-03-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 CO689_RS12170 6480050cba445f1ee19e47faef84e603 207 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 162 174 1.7E-10 T 28-03-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 CO689_RS12170 6480050cba445f1ee19e47faef84e603 207 TIGRFAM TIGR00498 lexA: repressor LexA 1 206 5.6E-76 T 28-03-2018 IPR006200 Transcription regulator LexA GO:0004252|GO:0009432|GO:0045892 CO689_RS12170 6480050cba445f1ee19e47faef84e603 207 Pfam PF01726 LexA DNA binding domain 1 65 7.2E-28 T 28-03-2018 IPR006199 LexA repressor, DNA-binding domain GO:0004252|GO:0006508 CO689_RS12170 6480050cba445f1ee19e47faef84e603 207 Gene3D G3DSA:1.10.10.10 1 70 1.7E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS12170 6480050cba445f1ee19e47faef84e603 207 Gene3D G3DSA:2.10.109.10 89 207 2.5E-26 T 28-03-2018 CO689_RS12170 6480050cba445f1ee19e47faef84e603 207 Pfam PF00717 Peptidase S24-like 126 192 3.9E-17 T 28-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C CO689_RS12170 6480050cba445f1ee19e47faef84e603 207 SUPERFAMILY SSF46785 3 70 1.14E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS06560 fd9527196f7738d3bf1668f3f1b67453 945 TIGRFAM TIGR03062 pip_yhgE_Cterm: YhgE/Pip C-terminal domain 721 924 4.6E-51 T 28-03-2018 IPR017501 Phage infection protein, YhgE, C-terminal CO689_RS06560 fd9527196f7738d3bf1668f3f1b67453 945 Pfam PF12698 ABC-2 family transporter protein 22 168 7.7E-11 T 28-03-2018 CO689_RS06560 fd9527196f7738d3bf1668f3f1b67453 945 Pfam PF12698 ABC-2 family transporter protein 611 922 5.1E-20 T 28-03-2018 CO689_RS06560 fd9527196f7738d3bf1668f3f1b67453 945 Gene3D G3DSA:1.20.1480.30 232 356 0.019 T 28-03-2018 CO689_RS06560 fd9527196f7738d3bf1668f3f1b67453 945 Gene3D G3DSA:1.20.1480.30 512 607 3.2E-5 T 28-03-2018 CO689_RS06560 fd9527196f7738d3bf1668f3f1b67453 945 TIGRFAM TIGR03061 pip_yhgE_Nterm: YhgE/Pip N-terminal domain 11 172 2.4E-46 T 28-03-2018 IPR017500 Phage infection protein, YhgE, N-terminal CO689_RS06560 fd9527196f7738d3bf1668f3f1b67453 945 Gene3D G3DSA:3.40.1710.10 48 210 1.7E-25 T 28-03-2018 CO689_RS05280 e89dd458f253992dcc89aa6a62122069 130 Gene3D G3DSA:3.90.79.10 1 130 1.0E-27 T 28-03-2018 CO689_RS05280 e89dd458f253992dcc89aa6a62122069 130 PRINTS PR00502 NUDIX hydrolase family signature 47 62 6.5E-5 T 28-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CO689_RS05280 e89dd458f253992dcc89aa6a62122069 130 PRINTS PR00502 NUDIX hydrolase family signature 33 47 6.5E-5 T 28-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CO689_RS05280 e89dd458f253992dcc89aa6a62122069 130 Pfam PF00293 NUDIX domain 5 120 5.2E-14 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 CO689_RS05280 e89dd458f253992dcc89aa6a62122069 130 SUPERFAMILY SSF55811 2 127 1.49E-31 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CO689_RS02550 6cde697ff9fa5080e7ff37ade59eaf9b 419 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 9 407 8.9E-87 T 28-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 CO689_RS02550 6cde697ff9fa5080e7ff37ade59eaf9b 419 Gene3D G3DSA:3.65.10.10 223 418 1.3E-45 T 28-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 CO689_RS02550 6cde697ff9fa5080e7ff37ade59eaf9b 419 Gene3D G3DSA:3.65.10.10 23 222 5.3E-42 T 28-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 CO689_RS02550 6cde697ff9fa5080e7ff37ade59eaf9b 419 Hamap MF_00111 UDP-N-acetylglucosamine 1-carboxyvinyltransferase [murA]. 3 417 38.97 T 28-03-2018 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CO689_RS02550 6cde697ff9fa5080e7ff37ade59eaf9b 419 TIGRFAM TIGR01072 murA: UDP-N-acetylglucosamine 1-carboxyvinyltransferase 4 415 9.3E-155 T 28-03-2018 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CO689_RS02550 6cde697ff9fa5080e7ff37ade59eaf9b 419 SUPERFAMILY SSF55205 5 416 1.6E-121 T 28-03-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 CO689_RS00625 db8f03741996432734dc7c1f89280bad 196 Gene3D G3DSA:3.30.1190.10 16 97 7.0E-11 T 28-03-2018 CO689_RS00625 db8f03741996432734dc7c1f89280bad 196 SUPERFAMILY SSF47413 17 62 7.88E-9 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CO689_RS00625 db8f03741996432734dc7c1f89280bad 196 SMART SM00530 3 54 0.0044 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CO689_RS00625 db8f03741996432734dc7c1f89280bad 196 Pfam PF01381 Helix-turn-helix 17 54 3.5E-9 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CO689_RS12660 dc1199a34e3ee5d70100c5080aa56dc9 298 TIGRFAM TIGR00688 rarD: protein RarD 7 260 1.2E-64 T 28-03-2018 IPR004626 RarD protein GO:0005215|GO:0005887|GO:0006810 CO689_RS12660 dc1199a34e3ee5d70100c5080aa56dc9 298 Pfam PF00892 EamA-like transporter family 156 283 1.6E-7 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CO689_RS12660 dc1199a34e3ee5d70100c5080aa56dc9 298 Pfam PF00892 EamA-like transporter family 7 145 5.5E-16 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CO689_RS12660 dc1199a34e3ee5d70100c5080aa56dc9 298 SUPERFAMILY SSF103481 189 286 4.32E-10 T 28-03-2018 CO689_RS12660 dc1199a34e3ee5d70100c5080aa56dc9 298 SUPERFAMILY SSF103481 40 146 3.01E-13 T 28-03-2018 CO689_RS06420 e2b913692e2aba12b9fd77ab24a98a98 288 Gene3D G3DSA:3.30.420.40 3 118 4.3E-16 T 28-03-2018 CO689_RS06420 e2b913692e2aba12b9fd77ab24a98a98 288 Gene3D G3DSA:3.30.420.40 119 286 2.6E-33 T 28-03-2018 CO689_RS06420 e2b913692e2aba12b9fd77ab24a98a98 288 Pfam PF00480 ROK family 4 285 2.3E-37 T 28-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 CO689_RS06420 e2b913692e2aba12b9fd77ab24a98a98 288 SUPERFAMILY SSF53067 1 285 4.05E-43 T 28-03-2018 CO689_RS08435 34725dad45563aa4daef94822c2670d1 234 SMART SM00014 95 209 2.7E-10 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CO689_RS08435 34725dad45563aa4daef94822c2670d1 234 Gene3D G3DSA:1.20.144.10 36 219 3.2E-20 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CO689_RS08435 34725dad45563aa4daef94822c2670d1 234 SUPERFAMILY SSF48317 10 214 6.15E-28 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CO689_RS08435 34725dad45563aa4daef94822c2670d1 234 Pfam PF01569 PAP2 superfamily 99 212 4.2E-14 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CO689_RS10735 32d45ca9d2849932a0ae74f98d39595b 223 SUPERFAMILY SSF52317 1 217 1.39E-75 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CO689_RS10735 32d45ca9d2849932a0ae74f98d39595b 223 TIGRFAM TIGR01737 FGAM_synth_I: phosphoribosylformylglycinamidine synthase I 1 217 4.6E-98 T 28-03-2018 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 CO689_RS10735 32d45ca9d2849932a0ae74f98d39595b 223 SMART SM01211 1 218 2.2E-122 T 28-03-2018 CO689_RS10735 32d45ca9d2849932a0ae74f98d39595b 223 Gene3D G3DSA:3.40.50.880 1 220 4.9E-39 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CO689_RS10735 32d45ca9d2849932a0ae74f98d39595b 223 Hamap MF_00421 Phosphoribosylformylglycinamidine synthase subunit PurQ [purQ]. 1 216 42.582 T 28-03-2018 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 CO689_RS10735 32d45ca9d2849932a0ae74f98d39595b 223 PIRSF PIRSF001586 1 221 1.6E-81 T 28-03-2018 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 CO689_RS10735 32d45ca9d2849932a0ae74f98d39595b 223 Pfam PF13507 CobB/CobQ-like glutamine amidotransferase domain 2 201 2.7E-46 T 28-03-2018 CO689_RS09725 d2e80c75750ddca8b4aada23f18725ac 157 TIGRFAM TIGR01558 sm_term_P27: putative phage terminase, small subunit, P27 family 41 152 5.1E-20 T 28-03-2018 IPR006448 Putative phage terminase, small subunit, P27 family CO689_RS09725 d2e80c75750ddca8b4aada23f18725ac 157 Pfam PF05119 Phage terminase, small subunit 49 143 3.1E-21 T 28-03-2018 IPR006448 Putative phage terminase, small subunit, P27 family CO689_RS08935 44f30a753c2537c451b0481c36f7ade3 623 Pfam PF12848 ABC transporter 225 298 1.1E-11 T 28-03-2018 IPR032781 ABC-transporter extension domain CO689_RS08935 44f30a753c2537c451b0481c36f7ade3 623 SUPERFAMILY SSF52540 309 527 1.59E-47 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CO689_RS08935 44f30a753c2537c451b0481c36f7ade3 623 Pfam PF00005 ABC transporter 336 469 9.7E-23 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CO689_RS08935 44f30a753c2537c451b0481c36f7ade3 623 Pfam PF00005 ABC transporter 20 186 4.3E-26 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CO689_RS08935 44f30a753c2537c451b0481c36f7ade3 623 SMART SM00382 28 231 5.5E-13 T 28-03-2018 IPR003593 AAA+ ATPase domain CO689_RS08935 44f30a753c2537c451b0481c36f7ade3 623 SMART SM00382 343 521 6.3E-7 T 28-03-2018 IPR003593 AAA+ ATPase domain CO689_RS08935 44f30a753c2537c451b0481c36f7ade3 623 Pfam PF16326 ABC transporter C-terminal domain 554 619 1.3E-16 T 28-03-2018 IPR032524 ABC transporter Uup, C-terminal GO:0003677 CO689_RS08935 44f30a753c2537c451b0481c36f7ade3 623 ProSitePatterns PS00211 ABC transporters family signature. 158 172 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CO689_RS08935 44f30a753c2537c451b0481c36f7ade3 623 Gene3D G3DSA:3.40.50.300 281 551 9.0E-54 T 28-03-2018 CO689_RS08935 44f30a753c2537c451b0481c36f7ade3 623 Gene3D G3DSA:3.40.50.300 2 267 8.5E-53 T 28-03-2018 CO689_RS08935 44f30a753c2537c451b0481c36f7ade3 623 SUPERFAMILY SSF52540 9 240 1.49E-46 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CO689_RS04695 824b3ee22d69c9b8869eb7a21d00e12f 145 Pfam PF00746 LPXTG cell wall anchor motif 102 143 4.4E-4 T 28-03-2018 IPR019948 Gram-positive LPXTG cell wall anchor CO689_RS04695 824b3ee22d69c9b8869eb7a21d00e12f 145 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 108 143 0.0013 T 28-03-2018 CO689_RS03070 1bb3be75414eaa9170d7400dd861015e 120 Gene3D G3DSA:3.30.420.100 2 120 1.3E-41 T 28-03-2018 CO689_RS03070 1bb3be75414eaa9170d7400dd861015e 120 Pfam PF00861 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast 6 120 3.7E-49 T 28-03-2018 IPR005484 Ribosomal protein L18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CO689_RS03070 1bb3be75414eaa9170d7400dd861015e 120 TIGRFAM TIGR00060 L18_bact: ribosomal protein uL18 7 120 1.3E-42 T 28-03-2018 IPR004389 Ribosomal protein L18, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 CO689_RS03070 1bb3be75414eaa9170d7400dd861015e 120 Hamap MF_01337_B 50S ribosomal protein L18 [rplR]. 6 120 29.114 T 28-03-2018 IPR004389 Ribosomal protein L18, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 CO689_RS03070 1bb3be75414eaa9170d7400dd861015e 120 SUPERFAMILY SSF53137 7 118 3.92E-52 T 28-03-2018 CO689_RS04880 9101c258517949b91e38480d4d3b8e9a 377 SUPERFAMILY SSF54373 226 313 9.29E-16 T 28-03-2018 CO689_RS04880 9101c258517949b91e38480d4d3b8e9a 377 Pfam PF01266 FAD dependent oxidoreductase 3 351 6.1E-59 T 28-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 CO689_RS04880 9101c258517949b91e38480d4d3b8e9a 377 SUPERFAMILY SSF51905 314 367 7.77E-34 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CO689_RS04880 9101c258517949b91e38480d4d3b8e9a 377 SUPERFAMILY SSF51905 1 226 7.77E-34 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CO689_RS04880 9101c258517949b91e38480d4d3b8e9a 377 Gene3D G3DSA:3.50.50.60 1 375 2.1E-35 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CO689_RS09750 52ffde8ae40780321cecf0c975260361 412 TIGRFAM TIGR01554 major_cap_HK97: phage major capsid protein, HK97 family 5 400 1.3E-56 T 28-03-2018 IPR024455 Phage capsid CO689_RS09750 52ffde8ae40780321cecf0c975260361 412 Pfam PF05065 Phage capsid family 134 400 1.4E-35 T 28-03-2018 IPR024455 Phage capsid CO689_RS09750 52ffde8ae40780321cecf0c975260361 412 Gene3D G3DSA:3.30.2320.10 263 370 1.8E-20 T 28-03-2018 CO689_RS09750 52ffde8ae40780321cecf0c975260361 412 SUPERFAMILY SSF56563 130 402 3.53E-33 T 28-03-2018 CO689_RS03235 28c3309862cba8d5a611f342aa6b3d09 251 SUPERFAMILY SSF54593 71 127 3.12E-6 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CO689_RS03235 28c3309862cba8d5a611f342aa6b3d09 251 Gene3D G3DSA:3.10.180.10 3 140 2.5E-6 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CO689_RS03235 28c3309862cba8d5a611f342aa6b3d09 251 Pfam PF13468 Glyoxalase-like domain 6 192 9.9E-33 T 28-03-2018 IPR025870 Glyoxalase-like domain CO689_RS03235 28c3309862cba8d5a611f342aa6b3d09 251 Gene3D G3DSA:3.10.180.10 167 249 0.31 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CO689_RS13395 402912584675d5ee6df3929952627442 160 SUPERFAMILY SSF46557 5 79 1.07E-27 T 28-03-2018 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 CO689_RS13395 402912584675d5ee6df3929952627442 160 PIRSF PIRSF006092 1 160 1.8E-52 T 28-03-2018 IPR023459 Transcription elongation factor GreA/GreB family GO:0070063 CO689_RS13395 402912584675d5ee6df3929952627442 160 Gene3D G3DSA:3.10.50.30 78 159 3.7E-25 T 28-03-2018 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 CO689_RS13395 402912584675d5ee6df3929952627442 160 Pfam PF03449 Transcription elongation factor, N-terminal 8 76 1.5E-32 T 28-03-2018 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 CO689_RS13395 402912584675d5ee6df3929952627442 160 TIGRFAM TIGR01462 greA: transcription elongation factor GreA 8 157 7.1E-56 T 28-03-2018 IPR006359 Transcription elongation factor GreA GO:0003677|GO:0032784 CO689_RS13395 402912584675d5ee6df3929952627442 160 SUPERFAMILY SSF54534 83 158 4.71E-20 T 28-03-2018 CO689_RS13395 402912584675d5ee6df3929952627442 160 Gene3D G3DSA:1.10.287.180 6 77 7.1E-33 T 28-03-2018 CO689_RS13395 402912584675d5ee6df3929952627442 160 Pfam PF01272 Transcription elongation factor, GreA/GreB, C-term 84 158 2.6E-26 T 28-03-2018 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 CO689_RS13395 402912584675d5ee6df3929952627442 160 ProSitePatterns PS00829 Prokaryotic transcription elongation factors signature 1. 20 51 - T 28-03-2018 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 CO689_RS13395 402912584675d5ee6df3929952627442 160 Hamap MF_00105 Transcription elongation factor GreA [greA]. 5 158 33.023 T 28-03-2018 IPR028624 Transcription elongation factor GreA/GreB GO:0003677|GO:0032784|GO:0070063 CO689_RS09340 6c19e9003914d6121184c6b3961a5142 505 Gene3D G3DSA:3.40.720.10 297 505 1.5E-33 T 28-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 CO689_RS09340 6c19e9003914d6121184c6b3961a5142 505 Hamap MF_01038 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [gpmI]. 4 504 48.504 T 28-03-2018 IPR005995 Phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent GO:0004619|GO:0006007 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CO689_RS09340 6c19e9003914d6121184c6b3961a5142 505 TIGRFAM TIGR01307 pgm_bpd_ind: phosphoglycerate mutase (2,3-diphosphoglycerate-independent) 5 503 7.4E-208 T 28-03-2018 IPR005995 Phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent GO:0004619|GO:0006007 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CO689_RS09340 6c19e9003914d6121184c6b3961a5142 505 Pfam PF01676 Metalloenzyme superfamily 5 492 6.5E-74 T 28-03-2018 IPR006124 Metalloenzyme GO:0003824|GO:0046872 CO689_RS09340 6c19e9003914d6121184c6b3961a5142 505 Pfam PF06415 BPG-independent PGAM N-terminus (iPGM_N) 82 293 1.3E-83 T 28-03-2018 IPR011258 BPG-independent PGAM, N-terminal GO:0004619|GO:0005737|GO:0006007|GO:0030145 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CO689_RS09340 6c19e9003914d6121184c6b3961a5142 505 SUPERFAMILY SSF53649 5 77 4.64E-68 T 28-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 CO689_RS09340 6c19e9003914d6121184c6b3961a5142 505 SUPERFAMILY SSF53649 309 503 4.64E-68 T 28-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 CO689_RS09340 6c19e9003914d6121184c6b3961a5142 505 PIRSF PIRSF001492 1 505 2.1E-199 T 28-03-2018 IPR005995 Phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent GO:0004619|GO:0006007 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CO689_RS09340 6c19e9003914d6121184c6b3961a5142 505 Gene3D G3DSA:3.40.1450.10 77 296 3.2E-94 T 28-03-2018 CO689_RS09340 6c19e9003914d6121184c6b3961a5142 505 SUPERFAMILY SSF64158 77 303 7.59E-85 T 28-03-2018 IPR011258 BPG-independent PGAM, N-terminal GO:0004619|GO:0005737|GO:0006007|GO:0030145 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CO689_RS11640 12eac57431c6bdf859ea1244fc8724a7 296 SUPERFAMILY SSF102405 86 290 2.5E-26 T 28-03-2018 CO689_RS11640 12eac57431c6bdf859ea1244fc8724a7 296 TIGRFAM TIGR00732 dprA: DNA protecting protein DprA 78 291 5.2E-63 T 28-03-2018 IPR003488 DNA recombination-mediator protein A GO:0009294 CO689_RS11640 12eac57431c6bdf859ea1244fc8724a7 296 Gene3D G3DSA:3.40.50.450 118 266 2.0E-32 T 28-03-2018 CO689_RS11640 12eac57431c6bdf859ea1244fc8724a7 296 Pfam PF02481 DNA recombination-mediator protein A 78 283 5.5E-67 T 28-03-2018 IPR003488 DNA recombination-mediator protein A GO:0009294 CO689_RS05675 59f5bb9526f9152b3cf5f549ac1e88e6 683 Gene3D G3DSA:3.40.50.300 469 607 8.7E-18 T 28-03-2018 CO689_RS05675 59f5bb9526f9152b3cf5f549ac1e88e6 683 Pfam PF00271 Helicase conserved C-terminal domain 504 597 1.1E-11 T 28-03-2018 IPR001650 Helicase, C-terminal CO689_RS05675 59f5bb9526f9152b3cf5f549ac1e88e6 683 SUPERFAMILY SSF52540 247 396 3.52E-30 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CO689_RS05675 59f5bb9526f9152b3cf5f549ac1e88e6 683 SUPERFAMILY SSF52540 472 602 3.52E-30 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CO689_RS05675 59f5bb9526f9152b3cf5f549ac1e88e6 683 Gene3D G3DSA:3.40.50.300 213 403 3.4E-23 T 28-03-2018 CO689_RS05675 59f5bb9526f9152b3cf5f549ac1e88e6 683 Pfam PF04851 Type III restriction enzyme, res subunit 231 395 4.0E-20 T 28-03-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 CO689_RS05675 59f5bb9526f9152b3cf5f549ac1e88e6 683 Pfam PF13091 PLD-like domain 25 192 1.5E-9 T 28-03-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 CO689_RS05675 59f5bb9526f9152b3cf5f549ac1e88e6 683 SMART SM00490 518 599 8.4E-10 T 28-03-2018 IPR001650 Helicase, C-terminal CO689_RS05675 59f5bb9526f9152b3cf5f549ac1e88e6 683 SMART SM00487 230 430 2.2E-12 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CO689_RS11095 0979905d938bc802fc8e69e1a981e204 204 Gene3D G3DSA:1.20.1300.10 3 204 9.3E-47 T 28-03-2018 CO689_RS11095 0979905d938bc802fc8e69e1a981e204 204 Pfam PF01127 Succinate dehydrogenase/Fumarate reductase transmembrane subunit 89 193 2.5E-13 T 28-03-2018 IPR000701 Succinate dehydrogenase/fumarate reductase type B, transmembrane subunit GO:0016627 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CO689_RS11095 0979905d938bc802fc8e69e1a981e204 204 SUPERFAMILY SSF81343 3 203 6.67E-57 T 28-03-2018 IPR034804 Fumarate reductase/succinate dehydrogenase, transmembrane subunit GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CO689_RS11095 0979905d938bc802fc8e69e1a981e204 204 TIGRFAM TIGR02046 sdhC_b558_fam: succinate dehydrogenase (or fumarate reductase) cytochrome b subunit, b558 family 7 204 8.6E-42 T 28-03-2018 IPR011138 Succinate dehydrogenase cytochrome b558 subunit CO689_RS11095 0979905d938bc802fc8e69e1a981e204 204 PIRSF PIRSF000170 3 204 2.9E-92 T 28-03-2018 IPR016002 Succinate dehydrogenase cytochrome b558 subunit, Firmicute CO689_RS01875 652ca7e1a5963b250ed04fc64d4308ea 308 SUPERFAMILY SSF64182 1 307 1.02E-77 T 28-03-2018 CO689_RS01875 652ca7e1a5963b250ed04fc64d4308ea 308 Gene3D G3DSA:3.90.1640.10 1 188 5.8E-63 T 28-03-2018 CO689_RS01875 652ca7e1a5963b250ed04fc64d4308ea 308 SMART SM01131 181 307 1.4E-54 T 28-03-2018 IPR004097 DHHA2 domain GO:0005737|GO:0016462 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 CO689_RS01875 652ca7e1a5963b250ed04fc64d4308ea 308 Pfam PF02833 DHHA2 domain 183 305 2.4E-18 T 28-03-2018 IPR004097 DHHA2 domain GO:0005737|GO:0016462 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 CO689_RS01875 652ca7e1a5963b250ed04fc64d4308ea 308 Pfam PF01368 DHH family 4 146 1.5E-26 T 28-03-2018 IPR001667 DDH domain KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 CO689_RS01875 652ca7e1a5963b250ed04fc64d4308ea 308 Hamap MF_00207 Probable manganese-dependent inorganic pyrophosphatase [ppaC]. 3 308 43.696 T 28-03-2018 IPR022934 Manganese-dependent inorganic pyrophosphatase, probable GO:0004427 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 CO689_RS03535 7e12a22dbf8bb0a2984f481e7212bcf5 269 Pfam PF00459 Inositol monophosphatase family 32 257 1.7E-30 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CO689_RS03535 7e12a22dbf8bb0a2984f481e7212bcf5 269 PRINTS PR00377 Inositol monophosphatase superfamily signature 41 61 7.0E-16 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CO689_RS03535 7e12a22dbf8bb0a2984f481e7212bcf5 269 PRINTS PR00377 Inositol monophosphatase superfamily signature 63 79 7.0E-16 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CO689_RS03535 7e12a22dbf8bb0a2984f481e7212bcf5 269 PRINTS PR00377 Inositol monophosphatase superfamily signature 85 101 7.0E-16 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CO689_RS03535 7e12a22dbf8bb0a2984f481e7212bcf5 269 PRINTS PR00377 Inositol monophosphatase superfamily signature 174 195 7.0E-16 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CO689_RS03535 7e12a22dbf8bb0a2984f481e7212bcf5 269 PRINTS PR00377 Inositol monophosphatase superfamily signature 134 157 7.0E-16 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CO689_RS03535 7e12a22dbf8bb0a2984f481e7212bcf5 269 PRINTS PR00377 Inositol monophosphatase superfamily signature 205 229 7.0E-16 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CO689_RS03535 7e12a22dbf8bb0a2984f481e7212bcf5 269 SUPERFAMILY SSF56655 25 257 4.06E-49 T 28-03-2018 CO689_RS03535 7e12a22dbf8bb0a2984f481e7212bcf5 269 Gene3D G3DSA:3.30.540.10 1 145 4.6E-28 T 28-03-2018 CO689_RS03535 7e12a22dbf8bb0a2984f481e7212bcf5 269 Gene3D G3DSA:3.40.190.80 149 264 9.4E-16 T 28-03-2018 CO689_RS03840 b075a17d30dec73a54784b44254db37e 330 Pfam PF00107 Zinc-binding dehydrogenase 162 273 2.8E-15 T 28-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CO689_RS03840 b075a17d30dec73a54784b44254db37e 330 Gene3D G3DSA:3.90.180.10 1 142 2.2E-29 T 28-03-2018 CO689_RS03840 b075a17d30dec73a54784b44254db37e 330 Gene3D G3DSA:3.40.50.720 143 295 7.0E-21 T 28-03-2018 CO689_RS03840 b075a17d30dec73a54784b44254db37e 330 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 32 90 1.6E-6 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CO689_RS03840 b075a17d30dec73a54784b44254db37e 330 SUPERFAMILY SSF51735 119 293 1.62E-35 T 28-03-2018 IPR016040 NAD(P)-binding domain CO689_RS03840 b075a17d30dec73a54784b44254db37e 330 SMART SM00829 18 325 4.5E-7 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CO689_RS03840 b075a17d30dec73a54784b44254db37e 330 TIGRFAM TIGR02823 oxido_YhdH: putative quinone oxidoreductase, YhdH/YhfP family 6 327 2.7E-131 T 28-03-2018 IPR014188 Acrylyl-CoA reductase AcuI CO689_RS03840 b075a17d30dec73a54784b44254db37e 330 SUPERFAMILY SSF50129 5 146 3.77E-40 T 28-03-2018 IPR011032 GroES-like CO689_RS04140 f172568aa5e36c5970a635f53bdea59f 229 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 42 211 4.1E-20 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CO689_RS04140 f172568aa5e36c5970a635f53bdea59f 229 SUPERFAMILY SSF161098 18 204 2.49E-35 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CO689_RS04140 f172568aa5e36c5970a635f53bdea59f 229 Gene3D G3DSA:1.10.3720.10 3 217 1.5E-28 T 28-03-2018 CO689_RS02020 19d4679718dc3abe9c7456b4e2faf8ac 188 Gene3D G3DSA:3.20.16.10 14 183 6.0E-26 T 28-03-2018 IPR035443 Herpesvirus/Caudovirus protease domain CO689_RS02020 19d4679718dc3abe9c7456b4e2faf8ac 188 TIGRFAM TIGR01543 proheadase_HK97: phage prohead protease, HK97 family 40 161 1.1E-22 T 28-03-2018 IPR006433 Prohead protease CO689_RS02020 19d4679718dc3abe9c7456b4e2faf8ac 188 Pfam PF04586 Caudovirus prohead serine protease 8 166 3.2E-30 T 28-03-2018 IPR006433 Prohead protease CO689_RS13565 9e5e0e4b62da03ab29744a79c5a835dc 94 Hamap MF_00539 50S ribosomal protein L27 [rpmA]. 9 92 27.098 T 28-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CO689_RS13565 9e5e0e4b62da03ab29744a79c5a835dc 94 TIGRFAM TIGR00062 L27: ribosomal protein bL27 9 89 2.4E-39 T 28-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CO689_RS13565 9e5e0e4b62da03ab29744a79c5a835dc 94 ProSitePatterns PS00831 Ribosomal protein L27 signature. 42 56 - T 28-03-2018 IPR018261 Ribosomal protein L27, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CO689_RS13565 9e5e0e4b62da03ab29744a79c5a835dc 94 PRINTS PR00063 Ribosomal protein L27 signature 12 36 2.5E-38 T 28-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CO689_RS13565 9e5e0e4b62da03ab29744a79c5a835dc 94 PRINTS PR00063 Ribosomal protein L27 signature 37 61 2.5E-38 T 28-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CO689_RS13565 9e5e0e4b62da03ab29744a79c5a835dc 94 PRINTS PR00063 Ribosomal protein L27 signature 62 86 2.5E-38 T 28-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CO689_RS13565 9e5e0e4b62da03ab29744a79c5a835dc 94 SUPERFAMILY SSF110324 10 90 3.38E-32 T 28-03-2018 CO689_RS13565 9e5e0e4b62da03ab29744a79c5a835dc 94 ProDom PD003114 RIBOSOMAL L27 50S RIBONUCLEOPROTEIN CHLOROPLAST MITOCHONDRIAL PEPTIDE 60S TRANSIT PRECURSOR 36 77 2.0E-17 T 28-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CO689_RS13565 9e5e0e4b62da03ab29744a79c5a835dc 94 Gene3D G3DSA:2.40.50.100 28 92 6.5E-29 T 28-03-2018 CO689_RS13565 9e5e0e4b62da03ab29744a79c5a835dc 94 Pfam PF01016 Ribosomal L27 protein 10 89 2.6E-34 T 28-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CO689_RS12105 25665108aad2955b6128023e2ee72441 267 Pfam PF08282 haloacid dehalogenase-like hydrolase 7 263 1.1E-69 T 28-03-2018 IPR023214 HAD-like domain CO689_RS12105 25665108aad2955b6128023e2ee72441 267 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 6 263 6.3E-59 T 28-03-2018 IPR000150 Cof family GO:0016787 CO689_RS12105 25665108aad2955b6128023e2ee72441 267 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 6 236 2.5E-24 T 28-03-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 CO689_RS12105 25665108aad2955b6128023e2ee72441 267 Gene3D G3DSA:3.40.50.1000 1 267 3.2E-48 T 28-03-2018 IPR023214 HAD-like domain CO689_RS12105 25665108aad2955b6128023e2ee72441 267 SUPERFAMILY SSF56784 2 267 1.71E-73 T 28-03-2018 IPR023214 HAD-like domain CO689_RS03255 d95ce345173544049521797d760b7ee8 366 Gene3D G3DSA:1.20.1250.20 9 172 0.0013 T 28-03-2018 CO689_RS03255 d95ce345173544049521797d760b7ee8 366 Gene3D G3DSA:3.30.565.10 244 363 1.2E-14 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CO689_RS03255 d95ce345173544049521797d760b7ee8 366 SUPERFAMILY SSF55874 248 361 6.02E-11 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CO689_RS03255 d95ce345173544049521797d760b7ee8 366 Pfam PF07730 Histidine kinase 181 242 3.8E-16 T 28-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 CO689_RS03255 d95ce345173544049521797d760b7ee8 366 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 280 330 2.2E-5 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CO689_RS11235 f2c635259875f875accf5bcda6ba4756 472 Hamap MF_02033 Cell division protein FtsA [ftsA]. 2 471 23.217 T 28-03-2018 IPR020823 Cell division protein FtsA GO:0007049 CO689_RS11235 f2c635259875f875accf5bcda6ba4756 472 Pfam PF02491 SHS2 domain inserted in FTSA 84 158 3.5E-9 T 28-03-2018 IPR003494 SHS2 domain inserted in FtsA GO:0005515|GO:0007049 CO689_RS11235 f2c635259875f875accf5bcda6ba4756 472 SUPERFAMILY SSF53067 195 361 1.98E-35 T 28-03-2018 CO689_RS11235 f2c635259875f875accf5bcda6ba4756 472 SMART SM00842 6 193 6.4E-44 T 28-03-2018 IPR003494 SHS2 domain inserted in FtsA GO:0005515|GO:0007049 CO689_RS11235 f2c635259875f875accf5bcda6ba4756 472 Gene3D G3DSA:3.30.420.40 1 183 1.1E-21 T 28-03-2018 CO689_RS11235 f2c635259875f875accf5bcda6ba4756 472 PIRSF PIRSF003101 1 471 6.6E-94 T 28-03-2018 IPR020823 Cell division protein FtsA GO:0007049 CO689_RS11235 f2c635259875f875accf5bcda6ba4756 472 SUPERFAMILY SSF53067 5 187 2.52E-34 T 28-03-2018 CO689_RS11235 f2c635259875f875accf5bcda6ba4756 472 Pfam PF14450 Cell division protein FtsA 203 364 9.6E-18 T 28-03-2018 CO689_RS11235 f2c635259875f875accf5bcda6ba4756 472 TIGRFAM TIGR01174 ftsA: cell division protein FtsA 6 364 2.3E-82 T 28-03-2018 IPR020823 Cell division protein FtsA GO:0007049 CO689_RS11235 f2c635259875f875accf5bcda6ba4756 472 Gene3D G3DSA:3.90.640.10 231 296 1.3E-19 T 28-03-2018 CO689_RS07965 6e76e823df53bec878a8790534d3c937 354 SMART SM00670 160 265 4.3E-4 T 28-03-2018 IPR002716 PIN domain CO689_RS07965 6e76e823df53bec878a8790534d3c937 354 Gene3D G3DSA:3.40.50.1010 159 283 3.4E-21 T 28-03-2018 IPR029060 PIN domain-like CO689_RS07965 6e76e823df53bec878a8790534d3c937 354 SUPERFAMILY SSF88723 162 286 3.92E-20 T 28-03-2018 IPR029060 PIN domain-like CO689_RS07965 6e76e823df53bec878a8790534d3c937 354 Pfam PF01938 TRAM domain 290 337 2.2E-6 T 28-03-2018 IPR002792 TRAM domain CO689_RS07965 6e76e823df53bec878a8790534d3c937 354 Gene3D G3DSA:2.40.50.140 284 353 1.6E-6 T 28-03-2018 CO689_RS11135 d5e7911005a179a976ec6789ee77d6a1 147 Gene3D G3DSA:3.10.180.10 1 147 2.2E-20 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CO689_RS11135 d5e7911005a179a976ec6789ee77d6a1 147 Pfam PF06983 3-demethylubiquinone-9 3-methyltransferase 5 138 1.5E-9 T 28-03-2018 IPR028973 PhnB-like CO689_RS11135 d5e7911005a179a976ec6789ee77d6a1 147 SUPERFAMILY SSF54593 3 143 1.36E-24 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CO689_RS12780 142dc7ed6d6acfa21a09246a111c2bb3 149 SUPERFAMILY SSF54919 1 149 1.57E-60 T 28-03-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CO689_RS12780 142dc7ed6d6acfa21a09246a111c2bb3 149 Hamap MF_00451 Nucleoside diphosphate kinase [ndk]. 1 136 37.027 T 28-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CO689_RS12780 142dc7ed6d6acfa21a09246a111c2bb3 149 Gene3D G3DSA:3.30.70.141 1 149 3.9E-61 T 28-03-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CO689_RS12780 142dc7ed6d6acfa21a09246a111c2bb3 149 ProSitePatterns PS00469 Nucleoside diphosphate kinases active site. 112 120 - T 28-03-2018 IPR023005 Nucleoside diphosphate kinase, active site KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CO689_RS12780 142dc7ed6d6acfa21a09246a111c2bb3 149 PRINTS PR01243 Nucleoside diphosphate kinase signature 112 131 5.7E-49 T 28-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CO689_RS12780 142dc7ed6d6acfa21a09246a111c2bb3 149 PRINTS PR01243 Nucleoside diphosphate kinase signature 89 105 5.7E-49 T 28-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CO689_RS12780 142dc7ed6d6acfa21a09246a111c2bb3 149 PRINTS PR01243 Nucleoside diphosphate kinase signature 48 67 5.7E-49 T 28-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CO689_RS12780 142dc7ed6d6acfa21a09246a111c2bb3 149 PRINTS PR01243 Nucleoside diphosphate kinase signature 4 26 5.7E-49 T 28-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CO689_RS12780 142dc7ed6d6acfa21a09246a111c2bb3 149 PRINTS PR01243 Nucleoside diphosphate kinase signature 68 85 5.7E-49 T 28-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CO689_RS12780 142dc7ed6d6acfa21a09246a111c2bb3 149 SMART SM00562 1 138 1.3E-88 T 28-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CO689_RS12780 142dc7ed6d6acfa21a09246a111c2bb3 149 Pfam PF00334 Nucleoside diphosphate kinase 2 135 1.1E-57 T 28-03-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CO689_RS06480 d56bdd3f20545b6ba64cb583b7d36370 134 SUPERFAMILY SSF102546 1 134 3.92E-38 T 28-03-2018 IPR023750 RbsD-like domain GO:0005996|GO:0016853|GO:0048029 Reactome: R-HSA-6787639 CO689_RS06480 d56bdd3f20545b6ba64cb583b7d36370 134 Hamap MF_01661 D-ribose pyranase [rbsD]. 1 134 29.449 T 28-03-2018 IPR023064 D-ribose pyranase GO:0016872 CO689_RS06480 d56bdd3f20545b6ba64cb583b7d36370 134 Pfam PF05025 RbsD / FucU transport protein family 1 133 6.4E-41 T 28-03-2018 IPR007721 D-ribose pyranase RbsD/L-fucose mutarotase FucU GO:0005996|GO:0016853|GO:0048029 Reactome: R-HSA-6787639 CO689_RS06480 d56bdd3f20545b6ba64cb583b7d36370 134 Gene3D G3DSA:3.40.1650.10 1 134 1.4E-28 T 28-03-2018 IPR023750 RbsD-like domain GO:0005996|GO:0016853|GO:0048029 Reactome: R-HSA-6787639 CO689_RS07320 da27a11ceb0eec3f1764a3c7c3efe818 260 Gene3D G3DSA:3.40.50.720 45 260 7.0E-63 T 28-03-2018 CO689_RS07320 da27a11ceb0eec3f1764a3c7c3efe818 260 Gene3D G3DSA:3.40.50.720 1 44 1.9E-10 T 28-03-2018 CO689_RS07320 da27a11ceb0eec3f1764a3c7c3efe818 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 156 175 1.5E-36 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CO689_RS07320 da27a11ceb0eec3f1764a3c7c3efe818 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 130 146 1.5E-36 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CO689_RS07320 da27a11ceb0eec3f1764a3c7c3efe818 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 221 241 1.5E-36 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CO689_RS07320 da27a11ceb0eec3f1764a3c7c3efe818 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 1.5E-36 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CO689_RS07320 da27a11ceb0eec3f1764a3c7c3efe818 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 177 194 1.5E-36 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CO689_RS07320 da27a11ceb0eec3f1764a3c7c3efe818 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 1.5E-36 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CO689_RS07320 da27a11ceb0eec3f1764a3c7c3efe818 260 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 143 171 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CO689_RS07320 da27a11ceb0eec3f1764a3c7c3efe818 260 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 82 93 2.3E-9 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CO689_RS07320 da27a11ceb0eec3f1764a3c7c3efe818 260 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 136 144 2.3E-9 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CO689_RS07320 da27a11ceb0eec3f1764a3c7c3efe818 260 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 156 175 2.3E-9 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CO689_RS07320 da27a11ceb0eec3f1764a3c7c3efe818 260 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 16 257 1.5E-58 T 28-03-2018 CO689_RS07320 da27a11ceb0eec3f1764a3c7c3efe818 260 SUPERFAMILY SSF51735 5 258 1.47E-81 T 28-03-2018 IPR016040 NAD(P)-binding domain CO689_RS07320 da27a11ceb0eec3f1764a3c7c3efe818 260 TIGRFAM TIGR02415 23BDH: acetoin reductases 7 260 1.9E-114 T 28-03-2018 IPR014007 Acetoin reductase GO:0019152|GO:0045150|GO:0055114 KEGG: 00072+1.1.1.30|KEGG: 00650+1.1.1.304+1.1.1.30|MetaCyc: PWY-6389 CO689_RS03085 848870b5a27bcb5118405f0ee21671fc 61 SUPERFAMILY SSF57716 3 61 6.49E-23 T 28-03-2018 CO689_RS03085 848870b5a27bcb5118405f0ee21671fc 61 Pfam PF00253 Ribosomal protein S14p/S29e 10 60 9.2E-25 T 28-03-2018 IPR001209 Ribosomal protein S14 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CO689_RS03085 848870b5a27bcb5118405f0ee21671fc 61 ProSitePatterns PS00527 Ribosomal protein S14 signature. 23 45 - T 28-03-2018 IPR018271 Ribosomal protein S14, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CO689_RS03085 848870b5a27bcb5118405f0ee21671fc 61 Hamap MF_01364_B 30S ribosomal protein S14 type Z [rpsZ]. 1 61 25.849 T 28-03-2018 IPR023053 Ribosomal protein S14, type Z CO689_RS03085 848870b5a27bcb5118405f0ee21671fc 61 Gene3D G3DSA:4.10.830.10 1 61 4.0E-23 T 28-03-2018 CO689_RS04365 e61d772b40dd96cf4be0de87c1a33487 225 SUPERFAMILY SSF143548 23 141 3.4E-27 T 28-03-2018 IPR029009 Allosteric substrate binding domain Reactome: R-HSA-977347 CO689_RS04365 e61d772b40dd96cf4be0de87c1a33487 225 TIGRFAM TIGR00719 sda_beta: L-serine dehydratase, iron-sulfur-dependent, beta subunit 7 182 2.2E-49 T 28-03-2018 IPR004643 Iron-sulphur-dependent L-serine dehydratase beta subunit GO:0003941|GO:0006094 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17 CO689_RS04365 e61d772b40dd96cf4be0de87c1a33487 225 PIRSF PIRSF036692 5 221 1.1E-54 T 28-03-2018 IPR004643 Iron-sulphur-dependent L-serine dehydratase beta subunit GO:0003941|GO:0006094 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17 CO689_RS04365 e61d772b40dd96cf4be0de87c1a33487 225 Pfam PF03315 Serine dehydratase beta chain 9 119 1.8E-11 T 28-03-2018 IPR005131 Serine dehydratase beta chain GO:0003941|GO:0006094|GO:0051539 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17 CO689_RS04365 e61d772b40dd96cf4be0de87c1a33487 225 Gene3D G3DSA:3.30.1330.90 17 142 4.5E-21 T 28-03-2018 IPR029009 Allosteric substrate binding domain Reactome: R-HSA-977347 CO689_RS02315 fd890b217686cb842f78fe75ca2d2c72 454 Hamap MF_02019 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [murF]. 4 451 33.463 T 28-03-2018 IPR005863 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase GO:0005524|GO:0005737|GO:0047480|GO:0071555 KEGG: 00300+6.3.2.10|KEGG: 00550+6.3.2.10|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CO689_RS02315 fd890b217686cb842f78fe75ca2d2c72 454 Pfam PF08245 Mur ligase middle domain 111 294 1.3E-42 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CO689_RS02315 fd890b217686cb842f78fe75ca2d2c72 454 SUPERFAMILY SSF63418 9 102 2.49E-25 T 28-03-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 CO689_RS02315 fd890b217686cb842f78fe75ca2d2c72 454 Gene3D G3DSA:3.40.1390.10 1 95 8.7E-27 T 28-03-2018 CO689_RS02315 fd890b217686cb842f78fe75ca2d2c72 454 Pfam PF02875 Mur ligase family, glutamate ligase domain 316 395 2.9E-14 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CO689_RS02315 fd890b217686cb842f78fe75ca2d2c72 454 Gene3D G3DSA:3.40.1190.10 96 311 2.9E-54 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CO689_RS02315 fd890b217686cb842f78fe75ca2d2c72 454 SUPERFAMILY SSF53244 316 450 9.52E-40 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CO689_RS02315 fd890b217686cb842f78fe75ca2d2c72 454 Pfam PF01225 Mur ligase family, catalytic domain 25 100 8.0E-13 T 28-03-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 CO689_RS02315 fd890b217686cb842f78fe75ca2d2c72 454 Gene3D G3DSA:3.90.190.20 314 454 2.7E-48 T 28-03-2018 CO689_RS02315 fd890b217686cb842f78fe75ca2d2c72 454 TIGRFAM TIGR01143 murF: UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase 31 450 4.3E-132 T 28-03-2018 IPR005863 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase GO:0005524|GO:0005737|GO:0047480|GO:0071555 KEGG: 00300+6.3.2.10|KEGG: 00550+6.3.2.10|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CO689_RS02315 fd890b217686cb842f78fe75ca2d2c72 454 SUPERFAMILY SSF53623 106 312 6.8E-49 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CO689_RS01625 f7e7ea189c5a4ba3fb18a7e51536b440 366 Pfam PF06081 Aromatic acid exporter family member 1 2 146 1.0E-28 T 28-03-2018 IPR010343 Aromatic acid exporter family member 1 CO689_RS09765 b6c5268ce520460d95cdf8cb0a917549 125 Pfam PF04883 Bacteriophage HK97-gp10, putative tail-component 21 91 9.1E-5 T 28-03-2018 IPR010064 Bacteriophage HK97-gp10, putative tail-component CO689_RS09765 b6c5268ce520460d95cdf8cb0a917549 125 TIGRFAM TIGR01725 phge_HK97_gp10: phage protein, HK97 gp10 family 20 125 4.3E-17 T 28-03-2018 IPR010064 Bacteriophage HK97-gp10, putative tail-component CO689_RS02430 b82ce493cd8e26c2521e8e07a2699a3d 423 TIGRFAM TIGR01072 murA: UDP-N-acetylglucosamine 1-carboxyvinyltransferase 5 420 3.7E-173 T 28-03-2018 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CO689_RS02430 b82ce493cd8e26c2521e8e07a2699a3d 423 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 9 411 3.4E-110 T 28-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 CO689_RS02430 b82ce493cd8e26c2521e8e07a2699a3d 423 Gene3D G3DSA:3.65.10.10 223 423 1.4E-50 T 28-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 CO689_RS02430 b82ce493cd8e26c2521e8e07a2699a3d 423 Hamap MF_00111 UDP-N-acetylglucosamine 1-carboxyvinyltransferase [murA]. 3 421 44.502 T 28-03-2018 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CO689_RS02430 b82ce493cd8e26c2521e8e07a2699a3d 423 Gene3D G3DSA:3.65.10.10 23 222 7.7E-50 T 28-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 CO689_RS02430 b82ce493cd8e26c2521e8e07a2699a3d 423 SUPERFAMILY SSF55205 4 422 1.21E-136 T 28-03-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 CO689_RS10565 9252259bee69f9aa2a950f9170142898 140 Gene3D G3DSA:3.40.630.30 2 140 3.9E-35 T 28-03-2018 CO689_RS10565 9252259bee69f9aa2a950f9170142898 140 SUPERFAMILY SSF55729 3 139 2.29E-35 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CO689_RS10565 9252259bee69f9aa2a950f9170142898 140 Pfam PF13673 Acetyltransferase (GNAT) domain 18 139 9.9E-23 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CO689_RS03105 1536c0b50d599fc02e28f4fde9f9b68b 87 Gene3D G3DSA:2.40.50.140 7 84 2.4E-30 T 28-03-2018 CO689_RS03105 1536c0b50d599fc02e28f4fde9f9b68b 87 PRINTS PR00973 Ribosomal protein S17 family signature 58 68 2.3E-11 T 28-03-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CO689_RS03105 1536c0b50d599fc02e28f4fde9f9b68b 87 PRINTS PR00973 Ribosomal protein S17 family signature 68 75 2.3E-11 T 28-03-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CO689_RS03105 1536c0b50d599fc02e28f4fde9f9b68b 87 PRINTS PR00973 Ribosomal protein S17 family signature 26 49 2.3E-11 T 28-03-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CO689_RS03105 1536c0b50d599fc02e28f4fde9f9b68b 87 ProSitePatterns PS00056 Ribosomal protein S17 signature. 58 70 - T 28-03-2018 IPR019979 Ribosomal protein S17, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CO689_RS03105 1536c0b50d599fc02e28f4fde9f9b68b 87 Hamap MF_01345_B 30S ribosomal protein S17 [rpsQ]. 7 82 23.954 T 28-03-2018 IPR019984 30S ribosomal protein S17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CO689_RS03105 1536c0b50d599fc02e28f4fde9f9b68b 87 TIGRFAM TIGR03635 uS17_bact: ribosomal protein uS17 7 78 3.5E-34 T 28-03-2018 IPR019984 30S ribosomal protein S17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CO689_RS03105 1536c0b50d599fc02e28f4fde9f9b68b 87 ProDom PD001295 RIBOSOMAL S17 30S RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 40S S11 S17P S11 7 78 8.0E-35 T 28-03-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CO689_RS03105 1536c0b50d599fc02e28f4fde9f9b68b 87 Pfam PF00366 Ribosomal protein S17 12 79 1.0E-31 T 28-03-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CO689_RS03105 1536c0b50d599fc02e28f4fde9f9b68b 87 SUPERFAMILY SSF50249 7 83 5.57E-31 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CO689_RS01895 0cea2e4b55e7070beb468353055c17e2 344 SUPERFAMILY SSF51004 30 343 3.92E-37 T 28-03-2018 IPR011048 Cytochrome cd1-nitrite reductase-like, haem d1 domain CO689_RS01895 0cea2e4b55e7070beb468353055c17e2 344 Pfam PF10282 Lactonase, 7-bladed beta-propeller 6 343 2.0E-108 T 28-03-2018 IPR019405 Lactonase, 7-bladed beta propeller CO689_RS01895 0cea2e4b55e7070beb468353055c17e2 344 Gene3D G3DSA:2.130.10.10 137 341 5.5E-27 T 28-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 CO689_RS01895 0cea2e4b55e7070beb468353055c17e2 344 Gene3D G3DSA:2.120.10.30 6 136 2.6E-4 T 28-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like CO689_RS09565 24784c2a75a3789a024b4a1c0501a9fa 104 Gene3D G3DSA:1.20.58.410 2 103 3.1E-4 T 28-03-2018 CO689_RS13095 0c74714b1690be76c0f4a0560a52213f 141 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 2 19 1.8E-4 T 28-03-2018 IPR012902 Prokaryotic N-terminal methylation site CO689_RS13095 0c74714b1690be76c0f4a0560a52213f 141 PIRSF PIRSF021292 1 140 5.8E-29 T 28-03-2018 IPR016785 ComG operon protein 4 GO:0030420 CO689_RS08180 573cd00b3b149cf92cf36eb9ec7322d5 210 Pfam PF00215 Orotidine 5'-phosphate decarboxylase / HUMPS family 2 202 5.7E-29 T 28-03-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CO689_RS08180 573cd00b3b149cf92cf36eb9ec7322d5 210 SMART SM00934 2 203 2.3E-35 T 28-03-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CO689_RS08180 573cd00b3b149cf92cf36eb9ec7322d5 210 TIGRFAM TIGR03128 RuMP_HxlA: 3-hexulose-6-phosphate synthase 2 206 6.4E-86 T 28-03-2018 IPR017553 3-hexulose-6-phosphate synthase GO:0005975|GO:0043801 KEGG: 00030+4.1.2.43|KEGG: 00680+4.1.2.43|MetaCyc: PWY-1861|MetaCyc: PWY-7796 CO689_RS08180 573cd00b3b149cf92cf36eb9ec7322d5 210 Gene3D G3DSA:3.20.20.70 1 208 2.0E-37 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CO689_RS08180 573cd00b3b149cf92cf36eb9ec7322d5 210 SUPERFAMILY SSF51366 3 208 3.33E-38 T 28-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 CO689_RS13725 b7e7d0ce1f2472d33186895056cc3730 195 TIGRFAM TIGR03598 GTPase_YsxC: ribosome biogenesis GTP-binding protein YsxC 9 191 2.3E-67 T 28-03-2018 IPR019987 GTP-binding protein, ribosome biogenesis, YsxC GO:0005525 CO689_RS13725 b7e7d0ce1f2472d33186895056cc3730 195 Gene3D G3DSA:3.40.50.300 74 192 2.5E-14 T 28-03-2018 CO689_RS13725 b7e7d0ce1f2472d33186895056cc3730 195 Pfam PF01926 50S ribosome-binding GTPase 27 145 5.7E-21 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CO689_RS13725 b7e7d0ce1f2472d33186895056cc3730 195 Gene3D G3DSA:3.40.50.300 9 73 1.5E-13 T 28-03-2018 CO689_RS13725 b7e7d0ce1f2472d33186895056cc3730 195 SUPERFAMILY SSF52540 4 194 1.14E-35 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CO689_RS13725 b7e7d0ce1f2472d33186895056cc3730 195 Hamap MF_00321 Probable GTP-binding protein EngB [engB]. 13 195 28.006 T 28-03-2018 IPR019987 GTP-binding protein, ribosome biogenesis, YsxC GO:0005525 CO689_RS11695 5b59c889e86fd2a60a5b9b79953a325a 255 ProSitePatterns PS01066 Undecaprenyl pyrophosphate synthase family signature. 198 215 - T 28-03-2018 IPR018520 Di-trans-poly-cis-decaprenylcistransferase-like, conserved site GO:0016765 Reactome: R-HSA-446199 CO689_RS11695 5b59c889e86fd2a60a5b9b79953a325a 255 Gene3D G3DSA:3.40.1180.10 11 254 2.6E-90 T 28-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 CO689_RS11695 5b59c889e86fd2a60a5b9b79953a325a 255 TIGRFAM TIGR00055 uppS: di-trans,poly-cis-decaprenylcistransferase 25 252 2.6E-83 T 28-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 CO689_RS11695 5b59c889e86fd2a60a5b9b79953a325a 255 Hamap MF_01139 Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) [uppS]. 25 253 39.001 T 28-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 CO689_RS11695 5b59c889e86fd2a60a5b9b79953a325a 255 SUPERFAMILY SSF64005 20 247 1.7E-86 T 28-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 CO689_RS11695 5b59c889e86fd2a60a5b9b79953a325a 255 Pfam PF01255 Putative undecaprenyl diphosphate synthase 32 252 7.7E-80 T 28-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 CO689_RS02920 2bdfdef2c7119c0973f9079790599ee9 337 SMART SM00829 14 330 0.0039 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CO689_RS02920 2bdfdef2c7119c0973f9079790599ee9 337 SUPERFAMILY SSF51735 123 297 8.37E-44 T 28-03-2018 IPR016040 NAD(P)-binding domain CO689_RS02920 2bdfdef2c7119c0973f9079790599ee9 337 Pfam PF16884 N-terminal domain of oxidoreductase 5 109 6.0E-27 T 28-03-2018 CO689_RS02920 2bdfdef2c7119c0973f9079790599ee9 337 Gene3D G3DSA:3.90.180.10 1 147 1.2E-25 T 28-03-2018 CO689_RS02920 2bdfdef2c7119c0973f9079790599ee9 337 SUPERFAMILY SSF50129 2 142 5.76E-29 T 28-03-2018 IPR011032 GroES-like CO689_RS02920 2bdfdef2c7119c0973f9079790599ee9 337 Pfam PF00107 Zinc-binding dehydrogenase 157 290 5.4E-17 T 28-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CO689_RS02920 2bdfdef2c7119c0973f9079790599ee9 337 Gene3D G3DSA:3.40.50.720 148 274 2.2E-25 T 28-03-2018 CO689_RS01830 46c044c51436c6686bad09a793363789 100 PIRSF PIRSF012508 1 100 4.3E-47 T 28-03-2018 IPR013368 TrpR homologue YerC/YecD CO689_RS01830 46c044c51436c6686bad09a793363789 100 Gene3D G3DSA:1.10.1270.10 1 100 5.4E-35 T 28-03-2018 CO689_RS01830 46c044c51436c6686bad09a793363789 100 Pfam PF01371 Trp repressor protein 10 94 2.0E-34 T 28-03-2018 IPR000831 Trp repressor GO:0003700|GO:0005622|GO:0006355 CO689_RS01830 46c044c51436c6686bad09a793363789 100 TIGRFAM TIGR02531 yecD_yerC: TrpR homolog YerC/YecD 7 94 1.1E-49 T 28-03-2018 IPR013368 TrpR homologue YerC/YecD CO689_RS01830 46c044c51436c6686bad09a793363789 100 SUPERFAMILY SSF48295 3 95 1.1E-31 T 28-03-2018 IPR010921 Trp repressor/replication initiator GO:0043565 CO689_RS02520 f72180cddd4b3d44e83cc13aecd6ba42 358 TIGRFAM TIGR00019 prfA: peptide chain release factor 1 2 354 2.5E-161 T 28-03-2018 IPR004373 Peptide chain release factor 1 GO:0005737|GO:0006415|GO:0016149 CO689_RS02520 f72180cddd4b3d44e83cc13aecd6ba42 358 SMART SM00937 63 177 1.4E-61 T 28-03-2018 IPR005139 Peptide chain release factor GO:0006415 CO689_RS02520 f72180cddd4b3d44e83cc13aecd6ba42 358 Gene3D G3DSA:3.30.160.20 208 314 2.1E-28 T 28-03-2018 CO689_RS02520 f72180cddd4b3d44e83cc13aecd6ba42 358 Hamap MF_00093 Peptide chain release factor 1 [prfA]. 1 354 39.891 T 28-03-2018 IPR004373 Peptide chain release factor 1 GO:0005737|GO:0006415|GO:0016149 CO689_RS02520 f72180cddd4b3d44e83cc13aecd6ba42 358 ProSitePatterns PS00745 Prokaryotic-type class I peptide chain release factors signature. 226 242 - T 28-03-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 CO689_RS02520 f72180cddd4b3d44e83cc13aecd6ba42 358 Gene3D G3DSA:1.20.58.410 2 94 6.3E-20 T 28-03-2018 CO689_RS02520 f72180cddd4b3d44e83cc13aecd6ba42 358 Pfam PF00472 RF-1 domain 210 318 1.5E-38 T 28-03-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 CO689_RS02520 f72180cddd4b3d44e83cc13aecd6ba42 358 SUPERFAMILY SSF75620 8 350 2.35E-131 T 28-03-2018 CO689_RS02520 f72180cddd4b3d44e83cc13aecd6ba42 358 Pfam PF03462 PCRF domain 9 202 1.9E-72 T 28-03-2018 IPR005139 Peptide chain release factor GO:0006415 CO689_RS13345 13d388b8301bfccb7cb202f797f3a272 227 SUPERFAMILY SSF47781 152 227 2.45E-28 T 28-03-2018 IPR010994 RuvA domain 2-like CO689_RS13345 13d388b8301bfccb7cb202f797f3a272 227 Gene3D G3DSA:1.10.150.20 126 184 2.4E-12 T 28-03-2018 CO689_RS13345 13d388b8301bfccb7cb202f797f3a272 227 Gene3D G3DSA:1.10.150.310 185 227 4.2E-19 T 28-03-2018 CO689_RS13345 13d388b8301bfccb7cb202f797f3a272 227 Pfam PF12836 Helix-hairpin-helix motif 164 226 6.1E-24 T 28-03-2018 CO689_RS13345 13d388b8301bfccb7cb202f797f3a272 227 TIGRFAM TIGR00426 TIGR00426: competence protein ComEA helix-hairpin-helix repeat region 165 227 4.8E-21 T 28-03-2018 IPR004509 Competence protein ComEA, helix-hairpin-helix domain CO689_RS13345 13d388b8301bfccb7cb202f797f3a272 227 SMART SM00278 205 224 0.028 T 28-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 CO689_RS13345 13d388b8301bfccb7cb202f797f3a272 227 SMART SM00278 175 194 0.97 T 28-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 CO689_RS13345 13d388b8301bfccb7cb202f797f3a272 227 Pfam PF10531 SLBB domain 85 137 2.2E-6 T 28-03-2018 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CO689_RS13415 8112ba152293dba2824cf88f1ad3bfb4 213 Gene3D G3DSA:3.40.50.150 1 211 8.1E-38 T 28-03-2018 CO689_RS13415 8112ba152293dba2824cf88f1ad3bfb4 213 Pfam PF01596 O-methyltransferase 41 209 1.8E-31 T 28-03-2018 IPR002935 O-methyltransferase, family 3 GO:0008171 CO689_RS13415 8112ba152293dba2824cf88f1ad3bfb4 213 SUPERFAMILY SSF53335 21 209 1.09E-39 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CO689_RS07675 09c5191deb817647507b4ae79cdd2bfc 257 SUPERFAMILY SSF51556 2 256 4.73E-95 T 28-03-2018 IPR032466 Metal-dependent hydrolase CO689_RS07675 09c5191deb817647507b4ae79cdd2bfc 257 ProSitePatterns PS01137 TatD deoxyribonuclease family signature 1. 2 10 - T 28-03-2018 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 CO689_RS07675 09c5191deb817647507b4ae79cdd2bfc 257 Gene3D G3DSA:3.20.20.140 1 257 2.4E-94 T 28-03-2018 CO689_RS07675 09c5191deb817647507b4ae79cdd2bfc 257 TIGRFAM TIGR00010 TIGR00010: hydrolase, TatD family 2 254 2.8E-95 T 28-03-2018 IPR015991 Uncharacterised hydrolase TatD-type GO:0004536 CO689_RS07675 09c5191deb817647507b4ae79cdd2bfc 257 Pfam PF01026 TatD related DNase 3 254 1.1E-87 T 28-03-2018 IPR001130 TatD family GO:0016788 CO689_RS07675 09c5191deb817647507b4ae79cdd2bfc 257 ProSitePatterns PS01091 TatD deoxyribonuclease family signature 3. 190 206 - T 28-03-2018 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 CO689_RS07675 09c5191deb817647507b4ae79cdd2bfc 257 PIRSF PIRSF005902 1 257 1.2E-88 T 28-03-2018 IPR001130 TatD family GO:0016788 CO689_RS07070 59228d2ed975dd6bf26d464a10117c06 249 Pfam PF04199 Putative cyclase 19 185 3.5E-32 T 28-03-2018 IPR007325 Kynurenine formamidase GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 CO689_RS07070 59228d2ed975dd6bf26d464a10117c06 249 SUPERFAMILY SSF102198 16 246 1.57E-52 T 28-03-2018 CO689_RS07070 59228d2ed975dd6bf26d464a10117c06 249 Gene3D G3DSA:3.50.30.50 14 249 1.8E-50 T 28-03-2018 CO689_RS11460 6568628a3eb6ce8fb18f9ad86cab2d19 247 SUPERFAMILY SSF81606 2 242 1.7E-61 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CO689_RS11460 6568628a3eb6ce8fb18f9ad86cab2d19 247 Pfam PF13672 Protein phosphatase 2C 12 197 4.5E-16 T 28-03-2018 CO689_RS11460 6568628a3eb6ce8fb18f9ad86cab2d19 247 SMART SM00332 1 240 1.0E-22 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CO689_RS11460 6568628a3eb6ce8fb18f9ad86cab2d19 247 SMART SM00331 8 242 4.1E-32 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CO689_RS11460 6568628a3eb6ce8fb18f9ad86cab2d19 247 Gene3D G3DSA:3.60.40.10 2 242 6.6E-42 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CO689_RS09945 3bf96338cbe9ef0b3a1658d8cfd032c7 78 Hamap MF_01542 UPF0349 protein . 1 77 28.381 T 28-03-2018 IPR022916 Protein of unknown function UPF0349 CO689_RS09945 3bf96338cbe9ef0b3a1658d8cfd032c7 78 ProDom PD058324 UPF0349 LMO2392 BLI03401/BL03152 SA0800 SAR0901 LIN2491 SERP0525 GK2958 BT9727_4649 BC4937 1 74 1.0E-33 T 28-03-2018 CO689_RS09945 3bf96338cbe9ef0b3a1658d8cfd032c7 78 Pfam PF07293 Protein of unknown function (DUF1450) 1 74 7.4E-35 T 28-03-2018 IPR009910 Protein of unknown function DUF1450 CO689_RS09840 56e15647e23f3011884e54357ec51c46 119 Pfam PF08861 Domain of unknown function DUF1828 2 84 1.8E-9 T 28-03-2018 IPR014960 Domain of unknown function DUF1828 CO689_RS08820 5de24d2f6937c9348145223f7777a6dc 252 Pfam PF08220 DeoR-like helix-turn-helix domain 6 60 3.6E-16 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CO689_RS08820 5de24d2f6937c9348145223f7777a6dc 252 Pfam PF00455 DeoR C terminal sensor domain 75 216 2.5E-42 T 28-03-2018 IPR014036 DeoR C-terminal sensor domain CO689_RS08820 5de24d2f6937c9348145223f7777a6dc 252 SUPERFAMILY SSF46785 4 76 2.44E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS08820 5de24d2f6937c9348145223f7777a6dc 252 SMART SM01134 73 232 5.0E-52 T 28-03-2018 CO689_RS08820 5de24d2f6937c9348145223f7777a6dc 252 Gene3D G3DSA:1.10.10.10 1 70 2.6E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS08820 5de24d2f6937c9348145223f7777a6dc 252 SMART SM00420 6 58 2.7E-17 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CO689_RS08820 5de24d2f6937c9348145223f7777a6dc 252 ProSitePatterns PS00894 DeoR-type HTH domain signature. 6 40 - T 28-03-2018 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 CO689_RS08820 5de24d2f6937c9348145223f7777a6dc 252 SUPERFAMILY SSF100950 74 226 3.77E-30 T 28-03-2018 CO689_RS08820 5de24d2f6937c9348145223f7777a6dc 252 Gene3D G3DSA:3.40.50.1360 71 240 1.5E-39 T 28-03-2018 CO689_RS08820 5de24d2f6937c9348145223f7777a6dc 252 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 38 56 9.3E-8 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CO689_RS08820 5de24d2f6937c9348145223f7777a6dc 252 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 24 38 9.3E-8 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CO689_RS02870 84a413091f9d253f6ae475a0afe84dd2 392 Gene3D G3DSA:1.20.1250.20 4 193 5.5E-17 T 28-03-2018 CO689_RS02870 84a413091f9d253f6ae475a0afe84dd2 392 Pfam PF05977 Transmembrane secretion effector 13 381 5.5E-33 T 28-03-2018 IPR010290 Transmembrane secretion effector CO689_RS02870 84a413091f9d253f6ae475a0afe84dd2 392 SUPERFAMILY SSF103473 6 384 3.92E-36 T 28-03-2018 IPR020846 Major facilitator superfamily domain CO689_RS02870 84a413091f9d253f6ae475a0afe84dd2 392 Gene3D G3DSA:1.20.1250.20 198 388 9.1E-13 T 28-03-2018 CO689_RS08595 154dc9bad1c90b0c857d73787b9a98b3 214 Pfam PF01027 Inhibitor of apoptosis-promoting Bax1 21 205 3.0E-15 T 28-03-2018 IPR006214 Bax inhibitor 1-related CO689_RS01040 61ca0a48dd8f57a90d2f6bcfd9cef597 282 Pfam PF01063 Amino-transferase class IV 31 251 5.0E-44 T 28-03-2018 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 CO689_RS01040 61ca0a48dd8f57a90d2f6bcfd9cef597 282 TIGRFAM TIGR01121 D_amino_aminoT: D-amino-acid transaminase 4 279 7.1E-129 T 28-03-2018 IPR005784 D-amino acid aminotransferase GO:0008483|GO:0030170|GO:0046416 KEGG: 00310+2.6.1.21|KEGG: 00330+2.6.1.21|KEGG: 00360+2.6.1.21|KEGG: 00472+2.6.1.21|KEGG: 00473+2.6.1.21 CO689_RS01040 61ca0a48dd8f57a90d2f6bcfd9cef597 282 Gene3D G3DSA:3.30.470.10 1 132 1.0E-28 T 28-03-2018 CO689_RS01040 61ca0a48dd8f57a90d2f6bcfd9cef597 282 ProSitePatterns PS00770 Aminotransferases class-IV signature. 179 208 - T 28-03-2018 IPR018300 Aminotransferase, class IV, conserved site GO:0003824|GO:0008152 Reactome: R-HSA-70895 CO689_RS01040 61ca0a48dd8f57a90d2f6bcfd9cef597 282 Gene3D G3DSA:3.20.10.10 133 282 2.8E-39 T 28-03-2018 CO689_RS01040 61ca0a48dd8f57a90d2f6bcfd9cef597 282 SUPERFAMILY SSF56752 4 275 2.35E-75 T 28-03-2018 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 CO689_RS12250 007071787727a56fad18ac4bfa57bed1 487 Pfam PF01235 Sodium:alanine symporter family 66 461 1.2E-161 T 28-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 CO689_RS12250 007071787727a56fad18ac4bfa57bed1 487 TIGRFAM TIGR00835 agcS: amino acid carrier protein 24 449 5.6E-153 T 28-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 CO689_RS12250 007071787727a56fad18ac4bfa57bed1 487 PRINTS PR00175 Sodium/alanine symporter signature 358 380 6.9E-61 T 28-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 CO689_RS12250 007071787727a56fad18ac4bfa57bed1 487 PRINTS PR00175 Sodium/alanine symporter signature 220 239 6.9E-61 T 28-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 CO689_RS12250 007071787727a56fad18ac4bfa57bed1 487 PRINTS PR00175 Sodium/alanine symporter signature 192 210 6.9E-61 T 28-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 CO689_RS12250 007071787727a56fad18ac4bfa57bed1 487 PRINTS PR00175 Sodium/alanine symporter signature 311 329 6.9E-61 T 28-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 CO689_RS12250 007071787727a56fad18ac4bfa57bed1 487 PRINTS PR00175 Sodium/alanine symporter signature 101 123 6.9E-61 T 28-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 CO689_RS12250 007071787727a56fad18ac4bfa57bed1 487 PRINTS PR00175 Sodium/alanine symporter signature 418 438 6.9E-61 T 28-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 CO689_RS12505 73661cec8301621a9bc0bba11c0cce35 212 Pfam PF10112 5-bromo-4-chloroindolyl phosphate hydrolysis protein 8 197 8.5E-60 T 28-03-2018 IPR018770 5-bromo-4-chloroindolyl phosphate hydrolysis protein CO689_RS02465 a4606683ed158ee4c89e63af0c65418c 174 Gene3D G3DSA:1.20.5.620 77 143 7.5E-6 T 28-03-2018 IPR028987 F-type ATP synthase subunit B-like, membrane domain CO689_RS02465 a4606683ed158ee4c89e63af0c65418c 174 Hamap MF_01398 ATP synthase subunit b [atpF]. 16 153 13.11 T 28-03-2018 IPR002146 ATP synthase, F0 complex, subunit b/b', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 CO689_RS02465 a4606683ed158ee4c89e63af0c65418c 174 TIGRFAM TIGR01144 ATP_synt_b: ATP synthase F0, B subunit 26 171 3.0E-39 T 28-03-2018 IPR005864 ATP synthase, F0 complex, subunit b, bacterial GO:0015078|GO:0015986|GO:0045263 CO689_RS02465 a4606683ed158ee4c89e63af0c65418c 174 Pfam PF00430 ATP synthase B/B' CF(0) 23 152 7.1E-32 T 28-03-2018 IPR002146 ATP synthase, F0 complex, subunit b/b', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 CO689_RS02465 a4606683ed158ee4c89e63af0c65418c 174 SUPERFAMILY SSF81573 78 135 1.7E-6 T 28-03-2018 IPR028987 F-type ATP synthase subunit B-like, membrane domain CO689_RS01690 165cd5d5914a4c0b8e1bfd3f1d97a502 165 SUPERFAMILY SSF54637 2 149 3.65E-42 T 28-03-2018 IPR029069 HotDog domain CO689_RS01690 165cd5d5914a4c0b8e1bfd3f1d97a502 165 Gene3D G3DSA:3.10.129.10 1 155 4.4E-42 T 28-03-2018 CO689_RS01690 165cd5d5914a4c0b8e1bfd3f1d97a502 165 Pfam PF03061 Thioesterase superfamily 21 92 4.3E-14 T 28-03-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 CO689_RS05505 958c33af39a0efae7a3cdb4088bc55f3 234 Pfam PF00106 short chain dehydrogenase 7 196 2.3E-59 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CO689_RS05505 958c33af39a0efae7a3cdb4088bc55f3 234 SUPERFAMILY SSF51735 1 231 1.46E-71 T 28-03-2018 IPR016040 NAD(P)-binding domain CO689_RS05505 958c33af39a0efae7a3cdb4088bc55f3 234 Gene3D G3DSA:3.40.50.720 4 161 2.4E-49 T 28-03-2018 CO689_RS05505 958c33af39a0efae7a3cdb4088bc55f3 234 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 156 175 4.0E-12 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CO689_RS05505 958c33af39a0efae7a3cdb4088bc55f3 234 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 83 94 4.0E-12 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CO689_RS05505 958c33af39a0efae7a3cdb4088bc55f3 234 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 136 144 4.0E-12 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CO689_RS05505 958c33af39a0efae7a3cdb4088bc55f3 234 PIRSF PIRSF000126 1 232 3.0E-56 T 28-03-2018 CO689_RS05505 958c33af39a0efae7a3cdb4088bc55f3 234 Gene3D G3DSA:3.40.50.720 162 232 1.2E-17 T 28-03-2018 CO689_RS05505 958c33af39a0efae7a3cdb4088bc55f3 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 130 146 2.5E-34 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CO689_RS05505 958c33af39a0efae7a3cdb4088bc55f3 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 156 175 2.5E-34 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CO689_RS05505 958c33af39a0efae7a3cdb4088bc55f3 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 177 194 2.5E-34 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CO689_RS05505 958c33af39a0efae7a3cdb4088bc55f3 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 83 94 2.5E-34 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CO689_RS05505 958c33af39a0efae7a3cdb4088bc55f3 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 2.5E-34 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CO689_RS05505 958c33af39a0efae7a3cdb4088bc55f3 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 200 220 2.5E-34 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CO689_RS10355 d6d6b267237e3bb85915cd0b443ef49c 209 Hamap MF_01020 Phosphoribosyl-ATP pyrophosphatase [hisE]. 103 189 18.55 T 28-03-2018 IPR008179 Phosphoribosyl-ATP pyrophosphohydrolase GO:0000105|GO:0004636 KEGG: 00340+3.6.1.31 CO689_RS10355 d6d6b267237e3bb85915cd0b443ef49c 209 SUPERFAMILY SSF101386 106 195 8.97E-26 T 28-03-2018 CO689_RS10355 d6d6b267237e3bb85915cd0b443ef49c 209 SUPERFAMILY SSF141734 8 102 6.02E-43 T 28-03-2018 CO689_RS10355 d6d6b267237e3bb85915cd0b443ef49c 209 TIGRFAM TIGR03188 histidine_hisI: phosphoribosyl-ATP diphosphatase 107 189 8.5E-31 T 28-03-2018 IPR008179 Phosphoribosyl-ATP pyrophosphohydrolase GO:0000105|GO:0004636 KEGG: 00340+3.6.1.31 CO689_RS10355 d6d6b267237e3bb85915cd0b443ef49c 209 ProDom PD002610 PHOSPHORIBOSYL-AMP BIOSYNTHESIS CYCLOHYDROLASE HYDROLASE HISTIDINE AMINO-ACID PRA-CH PHOSPHORIBOSYL-ATP BIFUNCTIONAL INCLUDES: 49 101 3.0E-16 T 28-03-2018 IPR002496 Phosphoribosyl-AMP cyclohydrolase domain GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 CO689_RS10355 d6d6b267237e3bb85915cd0b443ef49c 209 Hamap MF_01019 Histidine biosynthesis bifunctional protein HisIE [hisI]. 3 194 35.046 T 28-03-2018 IPR023019 Histidine biosynthesis bifunctional protein HisIE GO:0000105|GO:0004635|GO:0004636 KEGG: 00340+3.6.1.31+3.5.4.19 CO689_RS10355 d6d6b267237e3bb85915cd0b443ef49c 209 Gene3D G3DSA:1.10.287.1080 102 196 1.3E-23 T 28-03-2018 CO689_RS10355 d6d6b267237e3bb85915cd0b443ef49c 209 Pfam PF01503 Phosphoribosyl-ATP pyrophosphohydrolase 109 192 4.1E-14 T 28-03-2018 IPR021130 Phosphoribosyl-ATP pyrophosphohydrolase-like KEGG: 00340+3.6.1.31 CO689_RS10355 d6d6b267237e3bb85915cd0b443ef49c 209 Pfam PF01502 Phosphoribosyl-AMP cyclohydrolase 26 99 1.3E-31 T 28-03-2018 IPR002496 Phosphoribosyl-AMP cyclohydrolase domain GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 CO689_RS00590 eb478ab0f7181d7ae4febc512c74bf4c 483 Pfam PF00916 Sulfate permease family 144 354 1.0E-33 T 28-03-2018 IPR011547 SLC26A/SulP transporter domain GO:0008272|GO:0015116|GO:0016021 CO689_RS00590 eb478ab0f7181d7ae4febc512c74bf4c 483 Gene3D G3DSA:3.30.750.24 384 476 1.8E-7 T 28-03-2018 IPR002645 STAS domain CO689_RS00590 eb478ab0f7181d7ae4febc512c74bf4c 483 Pfam PF01740 STAS domain 399 475 5.7E-5 T 28-03-2018 IPR002645 STAS domain CO689_RS00590 eb478ab0f7181d7ae4febc512c74bf4c 483 SUPERFAMILY SSF52091 387 474 5.69E-7 T 28-03-2018 IPR002645 STAS domain CO689_RS04180 9d94e310820ca3dcf5b6d565f2959ee2 259 Pfam PF03649 Uncharacterised protein family (UPF0014) 4 241 4.1E-70 T 28-03-2018 IPR005226 UPF0014 family CO689_RS04180 9d94e310820ca3dcf5b6d565f2959ee2 259 TIGRFAM TIGR00245 TIGR00245: TIGR00245 family protein 2 247 5.0E-71 T 28-03-2018 IPR005226 UPF0014 family CO689_RS09455 25b6e7961542e50f7982f955af68565a 126 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 47 76 - T 28-03-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 CO689_RS09455 25b6e7961542e50f7982f955af68565a 126 SUPERFAMILY SSF51230 3 125 3.05E-47 T 28-03-2018 IPR011053 Single hybrid motif CO689_RS09455 25b6e7961542e50f7982f955af68565a 126 Pfam PF01597 Glycine cleavage H-protein 7 124 3.6E-50 T 28-03-2018 IPR033753 Glycine cleavage system H-protein/Simiate CO689_RS09455 25b6e7961542e50f7982f955af68565a 126 Hamap MF_00272 Glycine cleavage system H protein [gcvH]. 4 125 41.518 T 28-03-2018 IPR002930 Glycine cleavage system H-protein GO:0005960|GO:0019464 Reactome: R-HSA-389661|Reactome: R-HSA-6783984 CO689_RS09455 25b6e7961542e50f7982f955af68565a 126 TIGRFAM TIGR00527 gcvH: glycine cleavage system H protein 3 124 2.4E-56 T 28-03-2018 IPR017453 Glycine cleavage system H-protein, subgroup GO:0005960|GO:0019464 Reactome: R-HSA-389661|Reactome: R-HSA-6783984 CO689_RS09455 25b6e7961542e50f7982f955af68565a 126 Gene3D G3DSA:2.40.50.100 5 126 4.3E-50 T 28-03-2018 CO689_RS01200 7581eeef901251d484fdf8d2e1dad453 257 Pfam PF00326 Prolyl oligopeptidase family 93 251 1.5E-9 T 28-03-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 CO689_RS01200 7581eeef901251d484fdf8d2e1dad453 257 Gene3D G3DSA:3.40.50.1820 5 256 6.9E-25 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CO689_RS01200 7581eeef901251d484fdf8d2e1dad453 257 SUPERFAMILY SSF53474 19 251 2.62E-28 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CO689_RS06440 66e3c9a76886ff289be1712349481869 316 Gene3D G3DSA:1.20.58.340 127 245 8.0E-14 T 28-03-2018 CO689_RS06440 66e3c9a76886ff289be1712349481869 316 Gene3D G3DSA:3.30.460.20 1 125 1.4E-9 T 28-03-2018 CO689_RS06440 66e3c9a76886ff289be1712349481869 316 SUPERFAMILY SSF143865 3 249 1.83E-32 T 28-03-2018 CO689_RS06440 66e3c9a76886ff289be1712349481869 316 Pfam PF01544 CorA-like Mg2+ transporter protein 28 312 6.8E-54 T 28-03-2018 IPR002523 Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB GO:0016020|GO:0030001|GO:0046873|GO:0055085 CO689_RS06440 66e3c9a76886ff289be1712349481869 316 SUPERFAMILY SSF144083 251 314 6.41E-19 T 28-03-2018 CO689_RS06440 66e3c9a76886ff289be1712349481869 316 Gene3D G3DSA:1.20.58.340 246 316 2.1E-20 T 28-03-2018 CO689_RS04345 468bdc3efcd2f6c285ded3fd57d8820f 223 Pfam PF00881 Nitroreductase family 16 201 3.6E-27 T 28-03-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 CO689_RS04345 468bdc3efcd2f6c285ded3fd57d8820f 223 SUPERFAMILY SSF55469 10 221 5.23E-55 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CO689_RS04345 468bdc3efcd2f6c285ded3fd57d8820f 223 Gene3D G3DSA:3.40.109.10 3 223 6.1E-41 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CO689_RS12520 e5ad0d1483e3c8cc4e302639b98414da 447 TIGRFAM TIGR00796 livcs: branched-chain amino acid transport system II carrier protein 9 420 4.7E-136 T 28-03-2018 IPR004685 Branched-chain amino acid transport system II carrier protein GO:0015658|GO:0015803|GO:0016021 CO689_RS12520 e5ad0d1483e3c8cc4e302639b98414da 447 Pfam PF05525 Branched-chain amino acid transport protein 2 433 2.7E-133 T 28-03-2018 IPR004685 Branched-chain amino acid transport system II carrier protein GO:0015658|GO:0015803|GO:0016021 CO689_RS12225 d6de601bebccb9951e840c817b588822 153 SUPERFAMILY SSF54637 3 131 2.09E-36 T 28-03-2018 IPR029069 HotDog domain CO689_RS12225 d6de601bebccb9951e840c817b588822 153 TIGRFAM TIGR00051 TIGR00051: acyl-CoA thioester hydrolase, YbgC/YbaW family 11 121 1.2E-25 T 28-03-2018 IPR006684 Acyl-CoA thioester hydrolase YbgC/YbaW family GO:0016787 CO689_RS12225 d6de601bebccb9951e840c817b588822 153 Pfam PF03061 Thioesterase superfamily 18 101 5.2E-18 T 28-03-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 CO689_RS12225 d6de601bebccb9951e840c817b588822 153 Gene3D G3DSA:3.10.129.10 3 144 2.1E-33 T 28-03-2018 CO689_RS12225 d6de601bebccb9951e840c817b588822 153 PIRSF PIRSF003230 3 138 8.3E-29 T 28-03-2018 IPR006684 Acyl-CoA thioester hydrolase YbgC/YbaW family GO:0016787 CO689_RS11655 f894548b1ec8116fe910e84714f826ac 296 Gene3D G3DSA:1.10.443.10 108 286 3.8E-47 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 CO689_RS11655 f894548b1ec8116fe910e84714f826ac 296 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 6 85 3.0E-16 T 28-03-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 CO689_RS11655 f894548b1ec8116fe910e84714f826ac 296 Pfam PF00589 Phage integrase family 109 278 2.7E-47 T 28-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 CO689_RS11655 f894548b1ec8116fe910e84714f826ac 296 SUPERFAMILY SSF56349 12 285 1.82E-54 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CO689_RS11655 f894548b1ec8116fe910e84714f826ac 296 TIGRFAM TIGR02224 recomb_XerC: tyrosine recombinase XerC 7 294 9.2E-106 T 28-03-2018 IPR011931 Tyrosine recombinase XerC GO:0003677|GO:0006310|GO:0007049|GO:0007059|GO:0015074|GO:0051301 CO689_RS11655 f894548b1ec8116fe910e84714f826ac 296 Hamap MF_01808 Tyrosine recombinase XerC [xerC]. 3 292 52.875 T 28-03-2018 IPR023009 Tyrosine recombinase XerC/XerD CO689_RS11655 f894548b1ec8116fe910e84714f826ac 296 Gene3D G3DSA:1.10.150.130 1 107 4.5E-22 T 28-03-2018 IPR023109 Integrase/recombinase, N-terminal CO689_RS12090 cab7e0211035df0931cd259ea4d00daa 426 Gene3D G3DSA:3.30.360.10 158 298 8.8E-49 T 28-03-2018 CO689_RS12090 cab7e0211035df0931cd259ea4d00daa 426 SUPERFAMILY SSF51735 1 158 7.32E-37 T 28-03-2018 IPR016040 NAD(P)-binding domain CO689_RS12090 cab7e0211035df0931cd259ea4d00daa 426 ProSitePatterns PS01042 Homoserine dehydrogenase signature. 183 205 - T 28-03-2018 IPR019811 Homoserine dehydrogenase, conserved site GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 CO689_RS12090 cab7e0211035df0931cd259ea4d00daa 426 Gene3D G3DSA:3.40.50.720 1 157 2.7E-33 T 28-03-2018 CO689_RS12090 cab7e0211035df0931cd259ea4d00daa 426 Pfam PF00742 Homoserine dehydrogenase 137 315 9.2E-61 T 28-03-2018 IPR001342 Homoserine dehydrogenase, catalytic GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 CO689_RS12090 cab7e0211035df0931cd259ea4d00daa 426 SUPERFAMILY SSF55347 137 302 4.12E-49 T 28-03-2018 CO689_RS12090 cab7e0211035df0931cd259ea4d00daa 426 Pfam PF03447 Homoserine dehydrogenase, NAD binding domain 10 129 1.0E-19 T 28-03-2018 IPR005106 Aspartate/homoserine dehydrogenase, NAD-binding GO:0016491|GO:0050661|GO:0055114 CO689_RS12050 c9f30572b79d499d123e36fd66590cf8 492 Pfam PF13396 Phospholipase_D-nuclease N-terminal 23 66 4.6E-10 T 28-03-2018 IPR027379 Cardiolipin synthase N-terminal CO689_RS12050 c9f30572b79d499d123e36fd66590cf8 492 TIGRFAM TIGR04265 bac_cardiolipin: cardiolipin synthase 14 492 5.9E-205 T 28-03-2018 IPR022924 Cardiolipin synthase GO:0008808|GO:0016780|GO:0032049 CO689_RS12050 c9f30572b79d499d123e36fd66590cf8 492 Pfam PF13091 PLD-like domain 334 459 4.4E-29 T 28-03-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 CO689_RS12050 c9f30572b79d499d123e36fd66590cf8 492 Pfam PF13091 PLD-like domain 145 277 5.9E-13 T 28-03-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 CO689_RS12050 c9f30572b79d499d123e36fd66590cf8 492 Gene3D G3DSA:3.30.870.10 118 306 4.2E-34 T 28-03-2018 CO689_RS12050 c9f30572b79d499d123e36fd66590cf8 492 SUPERFAMILY SSF56024 93 322 6.91E-54 T 28-03-2018 CO689_RS12050 c9f30572b79d499d123e36fd66590cf8 492 SUPERFAMILY SSF56024 279 479 9.42E-55 T 28-03-2018 CO689_RS12050 c9f30572b79d499d123e36fd66590cf8 492 Gene3D G3DSA:3.30.870.10 307 477 3.4E-34 T 28-03-2018 CO689_RS12050 c9f30572b79d499d123e36fd66590cf8 492 Hamap MF_01916 Cardiolipin synthase. 19 492 42.194 T 28-03-2018 IPR030874 Cardiolipin synthase, Firmicutes-type GO:0008808|GO:0032049 CO689_RS12050 c9f30572b79d499d123e36fd66590cf8 492 SMART SM00155 227 254 2.4E-6 T 28-03-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 CO689_RS12050 c9f30572b79d499d123e36fd66590cf8 492 SMART SM00155 405 432 1.9E-8 T 28-03-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 CO689_RS11830 e82cbb94cd1f5e8581e4c0879cd80422 428 Pfam PF00675 Insulinase (Peptidase family M16) 63 171 4.0E-14 T 28-03-2018 IPR011765 Peptidase M16, N-terminal CO689_RS11830 e82cbb94cd1f5e8581e4c0879cd80422 428 Gene3D G3DSA:3.30.830.10 5 221 1.3E-44 T 28-03-2018 CO689_RS11830 e82cbb94cd1f5e8581e4c0879cd80422 428 Pfam PF05193 Peptidase M16 inactive domain 182 362 3.1E-22 T 28-03-2018 IPR007863 Peptidase M16, C-terminal CO689_RS11830 e82cbb94cd1f5e8581e4c0879cd80422 428 SUPERFAMILY SSF63411 6 230 5.41E-40 T 28-03-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 CO689_RS11830 e82cbb94cd1f5e8581e4c0879cd80422 428 SUPERFAMILY SSF63411 246 418 4.54E-19 T 28-03-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 CO689_RS11830 e82cbb94cd1f5e8581e4c0879cd80422 428 Gene3D G3DSA:3.30.830.10 222 420 3.9E-19 T 28-03-2018 CO689_RS11310 cc1ecca4d172396adf4163148c129eba 291 Hamap MF_01470 CRISPR-associated endonuclease Cas1 [cas1]. 1 256 15.526 T 28-03-2018 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 CO689_RS11310 cc1ecca4d172396adf4163148c129eba 291 TIGRFAM TIGR03639 cas1_NMENI: CRISPR-associated endonuclease Cas1, subtype II/NMENI 3 270 4.6E-84 T 28-03-2018 IPR019855 CRISPR-associated protein Cas1, NMENI subtype GO:0004520|GO:0043571|GO:0046872 CO689_RS11310 cc1ecca4d172396adf4163148c129eba 291 Pfam PF01867 CRISPR associated protein Cas1 7 237 3.9E-23 T 28-03-2018 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 CO689_RS11310 cc1ecca4d172396adf4163148c129eba 291 TIGRFAM TIGR00287 cas1: CRISPR-associated endonuclease Cas1 9 277 2.7E-25 T 28-03-2018 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 CO689_RS07325 20186adf44694d8f93b43c5bff092a23 156 SUPERFAMILY SSF54637 1 155 4.74E-41 T 28-03-2018 IPR029069 HotDog domain CO689_RS07325 20186adf44694d8f93b43c5bff092a23 156 Pfam PF13279 Thioesterase-like superfamily 11 129 7.0E-20 T 28-03-2018 CO689_RS07325 20186adf44694d8f93b43c5bff092a23 156 Gene3D G3DSA:3.10.129.10 1 144 1.2E-24 T 28-03-2018 CO689_RS02405 79b2cba9fc12b7a564d99254716344d0 225 SUPERFAMILY SSF53955 149 222 1.88E-14 T 28-03-2018 IPR023346 Lysozyme-like domain CO689_RS02405 79b2cba9fc12b7a564d99254716344d0 225 Gene3D G3DSA:1.10.530.10 51 225 4.1E-12 T 28-03-2018 CO689_RS02405 79b2cba9fc12b7a564d99254716344d0 225 Pfam PF06737 Transglycosylase-like domain 149 225 5.5E-22 T 28-03-2018 IPR010618 Transglycosylase-like CO689_RS03560 ddd83446857a61fc6c6b71cd3c1a0048 463 PIRSF PIRSF006060 1 461 3.1E-74 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CO689_RS03560 ddd83446857a61fc6c6b71cd3c1a0048 463 ProSitePatterns PS00218 Amino acid permeases signature. 39 69 - T 28-03-2018 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 CO689_RS03560 ddd83446857a61fc6c6b71cd3c1a0048 463 Pfam PF00324 Amino acid permease 15 430 1.4E-99 T 28-03-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0006810|GO:0016020|GO:0055085 CO689_RS11735 42c48ed621222966fcaef74aed558908 101 Gene3D G3DSA:3.30.1330.30 1 100 1.0E-19 T 28-03-2018 IPR029064 50S ribosomal protein L30e-like CO689_RS11735 42c48ed621222966fcaef74aed558908 101 SUPERFAMILY SSF55315 5 100 4.32E-27 T 28-03-2018 IPR029064 50S ribosomal protein L30e-like CO689_RS11735 42c48ed621222966fcaef74aed558908 101 Pfam PF01248 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family 6 95 6.4E-15 T 28-03-2018 IPR004038 Ribosomal protein L7Ae/L30e/S12e/Gadd45 CO689_RS10410 fab3230cb0c830ea950b0b25595c8702 231 Pfam PF02361 Cobalt transport protein 6 196 2.7E-15 T 28-03-2018 IPR003339 ABC/ECF transporter, transmembrane component CO689_RS02165 f21cb0d7ee4625f132fc0cab0b980705 139 Pfam PF00583 Acetyltransferase (GNAT) family 10 116 5.6E-15 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CO689_RS02165 f21cb0d7ee4625f132fc0cab0b980705 139 Gene3D G3DSA:3.40.630.30 1 139 2.9E-27 T 28-03-2018 CO689_RS02165 f21cb0d7ee4625f132fc0cab0b980705 139 TIGRFAM TIGR01575 rimI: ribosomal-protein-alanine acetyltransferase 5 135 3.2E-32 T 28-03-2018 IPR006464 N-acetyltransferase RimI/Ard1 GO:0006474|GO:0016407 CO689_RS02165 f21cb0d7ee4625f132fc0cab0b980705 139 SUPERFAMILY SSF55729 1 139 9.14E-29 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CO689_RS01675 7c5d6ac52cc5ec4d0816342d6cd7c550 175 SUPERFAMILY SSF52317 3 173 3.21E-41 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CO689_RS01675 7c5d6ac52cc5ec4d0816342d6cd7c550 175 Gene3D G3DSA:3.40.50.880 1 175 5.7E-39 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CO689_RS01675 7c5d6ac52cc5ec4d0816342d6cd7c550 175 Pfam PF01965 DJ-1/PfpI family 4 168 3.0E-48 T 28-03-2018 IPR002818 DJ-1/PfpI CO689_RS01675 7c5d6ac52cc5ec4d0816342d6cd7c550 175 TIGRFAM TIGR01382 PfpI: intracellular protease, PfpI family 5 171 1.2E-44 T 28-03-2018 IPR006286 Peptidase C56, PfpI CO689_RS00295 e07dc8bbad726840504f47c625753bb6 94 Gene3D G3DSA:1.10.287.910 21 70 6.2E-4 T 28-03-2018 CO689_RS11130 71125f81988d1f2857c0c2f0d233fdd9 124 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 4 114 1.1E-5 T 28-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CO689_RS11130 71125f81988d1f2857c0c2f0d233fdd9 124 SUPERFAMILY SSF54593 1 122 9.67E-19 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CO689_RS11130 71125f81988d1f2857c0c2f0d233fdd9 124 Gene3D G3DSA:3.10.180.10 1 123 1.4E-16 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CO689_RS05410 935571a855e070640167d181a3bbc086 276 Gene3D G3DSA:1.10.10.60 81 204 6.5E-9 T 28-03-2018 CO689_RS05410 935571a855e070640167d181a3bbc086 276 Gene3D G3DSA:2.60.120.10 11 80 3.4E-4 T 28-03-2018 IPR014710 RmlC-like jelly roll fold CO689_RS05410 935571a855e070640167d181a3bbc086 276 SMART SM00342 164 246 1.2E-7 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CO689_RS05410 935571a855e070640167d181a3bbc086 276 Gene3D G3DSA:1.10.10.60 205 249 3.2E-4 T 28-03-2018 CO689_RS11325 4ef67646023c2e84c2a33704f0bc56cc 175 SUPERFAMILY SSF53271 4 170 2.67E-37 T 28-03-2018 IPR029057 Phosphoribosyltransferase-like CO689_RS11325 4ef67646023c2e84c2a33704f0bc56cc 175 Gene3D G3DSA:3.40.50.2020 1 175 9.0E-29 T 28-03-2018 CO689_RS11325 4ef67646023c2e84c2a33704f0bc56cc 175 Hamap MF_01219 Bifunctional protein PyrR [pyrR]. 3 175 33.403 T 28-03-2018 IPR023050 Bifunctional protein PyrR KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 CO689_RS11325 4ef67646023c2e84c2a33704f0bc56cc 175 Pfam PF00156 Phosphoribosyl transferase domain 10 163 6.5E-19 T 28-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 CO689_RS03975 9585991ddf5cab871af426ea92e6d82e 104 Gene3D G3DSA:2.102.10.10 4 104 1.6E-25 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CO689_RS03975 9585991ddf5cab871af426ea92e6d82e 104 Pfam PF13806 Rieske-like [2Fe-2S] domain 8 101 1.4E-19 T 28-03-2018 IPR012748 Nitrite reductase [NAD(P)H] small subunit, NirD GO:0008942|GO:0042128|GO:0055114 CO689_RS03975 9585991ddf5cab871af426ea92e6d82e 104 SUPERFAMILY SSF50022 5 104 3.54E-33 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CO689_RS03975 9585991ddf5cab871af426ea92e6d82e 104 TIGRFAM TIGR02378 nirD_assim_sml: nitrite reductase [NAD(P)H], small subunit 6 102 8.5E-25 T 28-03-2018 IPR012748 Nitrite reductase [NAD(P)H] small subunit, NirD GO:0008942|GO:0042128|GO:0055114 CO689_RS06230 a2976b137ff992f420d5a2df16365216 1038 Pfam PF13086 AAA domain 280 517 1.1E-7 T 28-03-2018 CO689_RS06230 a2976b137ff992f420d5a2df16365216 1038 Pfam PF13086 AAA domain 733 792 1.3E-6 T 28-03-2018 CO689_RS06230 a2976b137ff992f420d5a2df16365216 1038 Gene3D G3DSA:3.40.50.300 276 809 3.9E-16 T 28-03-2018 CO689_RS06230 a2976b137ff992f420d5a2df16365216 1038 Pfam PF13087 AAA domain 903 1021 7.8E-13 T 28-03-2018 CO689_RS06230 a2976b137ff992f420d5a2df16365216 1038 SUPERFAMILY SSF52540 275 318 2.5E-30 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CO689_RS06230 a2976b137ff992f420d5a2df16365216 1038 SUPERFAMILY SSF52540 351 380 2.5E-30 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CO689_RS06230 a2976b137ff992f420d5a2df16365216 1038 SUPERFAMILY SSF52540 842 1023 2.5E-30 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CO689_RS06230 a2976b137ff992f420d5a2df16365216 1038 SUPERFAMILY SSF52540 731 808 2.5E-30 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CO689_RS06230 a2976b137ff992f420d5a2df16365216 1038 Gene3D G3DSA:3.40.50.300 849 1037 6.8E-17 T 28-03-2018 CO689_RS04350 150b4e864d799e6c344f24029d844888 177 SUPERFAMILY SSF52218 1 175 2.51E-39 T 28-03-2018 IPR029039 Flavoprotein-like domain CO689_RS04350 150b4e864d799e6c344f24029d844888 177 Gene3D G3DSA:3.40.50.360 1 177 3.5E-31 T 28-03-2018 IPR029039 Flavoprotein-like domain CO689_RS04350 150b4e864d799e6c344f24029d844888 177 Pfam PF02525 Flavodoxin-like fold 1 169 2.1E-41 T 28-03-2018 IPR003680 Flavodoxin-like fold CO689_RS11755 8037cc6a040e452719345f46b5179547 428 Gene3D G3DSA:1.20.1250.20 7 211 6.4E-14 T 28-03-2018 CO689_RS11755 8037cc6a040e452719345f46b5179547 428 SUPERFAMILY SSF103473 20 423 5.1E-33 T 28-03-2018 IPR020846 Major facilitator superfamily domain CO689_RS11755 8037cc6a040e452719345f46b5179547 428 Pfam PF07690 Major Facilitator Superfamily 43 369 2.7E-18 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CO689_RS11755 8037cc6a040e452719345f46b5179547 428 Gene3D G3DSA:1.20.1250.20 220 428 1.6E-12 T 28-03-2018 CO689_RS01135 d91e4c75220b8144c67b74cf81c688ad 281 Pfam PF01832 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase 132 259 4.0E-13 T 28-03-2018 IPR002901 Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain GO:0004040 CO689_RS01135 d91e4c75220b8144c67b74cf81c688ad 281 SMART SM00047 118 270 1.4E-35 T 28-03-2018 IPR002901 Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain GO:0004040 CO689_RS01135 d91e4c75220b8144c67b74cf81c688ad 281 Gene3D G3DSA:1.10.530.10 115 264 5.1E-25 T 28-03-2018 CO689_RS04890 be849d905266cdabe6a3083eb5f82a9d 255 Pfam PF05690 Thiazole biosynthesis protein ThiG 4 248 8.6E-100 T 28-03-2018 IPR033983 Thiazole synthase ThiG KEGG: 00730+2.8.1.10|MetaCyc: PWY-6891|MetaCyc: PWY-6892 CO689_RS04890 be849d905266cdabe6a3083eb5f82a9d 255 SUPERFAMILY SSF110399 1 238 2.35E-76 T 28-03-2018 CO689_RS04890 be849d905266cdabe6a3083eb5f82a9d 255 Gene3D G3DSA:3.20.20.70 1 253 5.7E-49 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CO689_RS04890 be849d905266cdabe6a3083eb5f82a9d 255 Hamap MF_00443 Thiazole synthase [thiG]. 1 254 40.039 T 28-03-2018 IPR008867 Thiazole synthase GO:0009228 KEGG: 00730+2.8.1.10|MetaCyc: PWY-6891|MetaCyc: PWY-6892 CO689_RS07405 83287bd905f2bd446eb6b612185235b0 294 Pfam PF02517 CAAX protease self-immunity 130 232 3.6E-12 T 28-03-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 CO689_RS03780 796221bebd3e33c5ab49c8029d5c74ac 447 PIRSF PIRSF032522 3 443 1.4E-129 T 28-03-2018 IPR023599 Membrane-associated protein TcaA GO:0016021|GO:0046677 CO689_RS10920 191f6007183356c7f6bebc400c65f069 448 Hamap MF_00221 Divalent metal cation transporter MntH [mntH]. 23 445 38.822 T 28-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 CO689_RS10920 191f6007183356c7f6bebc400c65f069 448 PRINTS PR00447 Natural resistance-associated macrophage protein signature 164 185 2.2E-62 T 28-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 CO689_RS10920 191f6007183356c7f6bebc400c65f069 448 PRINTS PR00447 Natural resistance-associated macrophage protein signature 327 346 2.2E-62 T 28-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 CO689_RS10920 191f6007183356c7f6bebc400c65f069 448 PRINTS PR00447 Natural resistance-associated macrophage protein signature 139 158 2.2E-62 T 28-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 CO689_RS10920 191f6007183356c7f6bebc400c65f069 448 PRINTS PR00447 Natural resistance-associated macrophage protein signature 216 239 2.2E-62 T 28-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 CO689_RS10920 191f6007183356c7f6bebc400c65f069 448 PRINTS PR00447 Natural resistance-associated macrophage protein signature 111 137 2.2E-62 T 28-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 CO689_RS10920 191f6007183356c7f6bebc400c65f069 448 PRINTS PR00447 Natural resistance-associated macrophage protein signature 389 408 2.2E-62 T 28-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 CO689_RS10920 191f6007183356c7f6bebc400c65f069 448 PRINTS PR00447 Natural resistance-associated macrophage protein signature 355 372 2.2E-62 T 28-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 CO689_RS10920 191f6007183356c7f6bebc400c65f069 448 TIGRFAM TIGR01197 nramp: metal ion transporter, metal ion (Mn2+/Fe2+) transporter (Nramp) family 31 413 1.8E-115 T 28-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 CO689_RS10920 191f6007183356c7f6bebc400c65f069 448 Pfam PF01566 Natural resistance-associated macrophage protein 52 419 4.6E-119 T 28-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 CO689_RS07010 9ad885fa6feecce873b0366387fc799a 370 Hamap MF_00365 DNA replication and repair protein RecF [recF]. 1 370 104.353 T 28-03-2018 IPR001238 DNA-binding, RecF GO:0003697|GO:0005524|GO:0006281 CO689_RS07010 9ad885fa6feecce873b0366387fc799a 370 ProSitePatterns PS00618 RecF protein signature 2. 312 330 - T 28-03-2018 IPR018078 DNA-binding, RecF, conserved site GO:0003697|GO:0005524|GO:0006281 CO689_RS07010 9ad885fa6feecce873b0366387fc799a 370 Gene3D G3DSA:3.40.50.300 1 370 1.7E-34 T 28-03-2018 CO689_RS07010 9ad885fa6feecce873b0366387fc799a 370 SUPERFAMILY SSF52540 244 353 3.27E-42 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CO689_RS07010 9ad885fa6feecce873b0366387fc799a 370 SUPERFAMILY SSF52540 1 217 3.27E-42 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CO689_RS07010 9ad885fa6feecce873b0366387fc799a 370 ProSitePatterns PS00617 RecF protein signature 1. 116 136 - T 28-03-2018 IPR018078 DNA-binding, RecF, conserved site GO:0003697|GO:0005524|GO:0006281 CO689_RS07010 9ad885fa6feecce873b0366387fc799a 370 Pfam PF02463 RecF/RecN/SMC N terminal domain 3 348 4.5E-16 T 28-03-2018 IPR003395 RecF/RecN/SMC, N-terminal CO689_RS07010 9ad885fa6feecce873b0366387fc799a 370 TIGRFAM TIGR00611 recf: DNA replication and repair protein RecF 1 367 5.1E-140 T 28-03-2018 IPR001238 DNA-binding, RecF GO:0003697|GO:0005524|GO:0006281 CO689_RS08345 be4e1c3edc6430f4b31668cc17589a79 554 Hamap MF_00123 Arginine--tRNA ligase [argS]. 9 554 27.117 T 28-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 CO689_RS08345 be4e1c3edc6430f4b31668cc17589a79 554 Gene3D G3DSA:3.40.50.620 107 364 3.6E-61 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CO689_RS08345 be4e1c3edc6430f4b31668cc17589a79 554 SUPERFAMILY SSF55190 2 113 2.49E-28 T 28-03-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 CO689_RS08345 be4e1c3edc6430f4b31668cc17589a79 554 SUPERFAMILY SSF47323 431 554 8.5E-33 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CO689_RS08345 be4e1c3edc6430f4b31668cc17589a79 554 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 132 141 - T 28-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 CO689_RS08345 be4e1c3edc6430f4b31668cc17589a79 554 SUPERFAMILY SSF52374 116 447 3.75E-97 T 28-03-2018 CO689_RS08345 be4e1c3edc6430f4b31668cc17589a79 554 PRINTS PR01038 Arginyl-tRNA synthetase signature 122 137 7.7E-25 T 28-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 CO689_RS08345 be4e1c3edc6430f4b31668cc17589a79 554 PRINTS PR01038 Arginyl-tRNA synthetase signature 161 174 7.7E-25 T 28-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 CO689_RS08345 be4e1c3edc6430f4b31668cc17589a79 554 PRINTS PR01038 Arginyl-tRNA synthetase signature 303 324 7.7E-25 T 28-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 CO689_RS08345 be4e1c3edc6430f4b31668cc17589a79 554 PRINTS PR01038 Arginyl-tRNA synthetase signature 137 153 7.7E-25 T 28-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 CO689_RS08345 be4e1c3edc6430f4b31668cc17589a79 554 Pfam PF00750 tRNA synthetases class I (R) 102 443 1.9E-28 T 28-03-2018 IPR035684 Arginyl-tRNA synthetase, catalytic core domain KEGG: 00970+6.1.1.19 CO689_RS08345 be4e1c3edc6430f4b31668cc17589a79 554 Pfam PF05746 DALR anticodon binding domain 437 554 1.6E-33 T 28-03-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 CO689_RS08345 be4e1c3edc6430f4b31668cc17589a79 554 SMART SM00836 436 554 4.1E-47 T 28-03-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 CO689_RS08345 be4e1c3edc6430f4b31668cc17589a79 554 Gene3D G3DSA:1.10.730.10 402 554 9.6E-43 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CO689_RS08345 be4e1c3edc6430f4b31668cc17589a79 554 SMART SM01016 5 93 5.3E-37 T 28-03-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 CO689_RS08345 be4e1c3edc6430f4b31668cc17589a79 554 Gene3D G3DSA:3.30.1360.70 3 106 8.9E-35 T 28-03-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 CO689_RS08345 be4e1c3edc6430f4b31668cc17589a79 554 TIGRFAM TIGR00456 argS: arginine--tRNA ligase 8 554 1.3E-155 T 28-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 CO689_RS08345 be4e1c3edc6430f4b31668cc17589a79 554 Pfam PF03485 Arginyl tRNA synthetase N terminal domain 10 93 5.0E-27 T 28-03-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 CO689_RS03760 3abc9697ab2de85b0b21575ef3edcc26 610 Pfam PF07690 Major Facilitator Superfamily 120 510 1.3E-52 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CO689_RS03760 3abc9697ab2de85b0b21575ef3edcc26 610 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 116 594 4.9E-136 T 28-03-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 CO689_RS03760 3abc9697ab2de85b0b21575ef3edcc26 610 Gene3D G3DSA:1.20.1250.20 109 301 1.2E-33 T 28-03-2018 CO689_RS03760 3abc9697ab2de85b0b21575ef3edcc26 610 Gene3D G3DSA:1.20.1250.20 360 610 3.7E-28 T 28-03-2018 CO689_RS03760 3abc9697ab2de85b0b21575ef3edcc26 610 PRINTS PR01036 Tetracycline resistance protein TetB signature 118 142 2.8E-10 T 28-03-2018 CO689_RS03760 3abc9697ab2de85b0b21575ef3edcc26 610 PRINTS PR01036 Tetracycline resistance protein TetB signature 239 263 2.8E-10 T 28-03-2018 CO689_RS03760 3abc9697ab2de85b0b21575ef3edcc26 610 PRINTS PR01036 Tetracycline resistance protein TetB signature 403 427 2.8E-10 T 28-03-2018 CO689_RS03760 3abc9697ab2de85b0b21575ef3edcc26 610 PRINTS PR01036 Tetracycline resistance protein TetB signature 178 200 2.8E-10 T 28-03-2018 CO689_RS03760 3abc9697ab2de85b0b21575ef3edcc26 610 SUPERFAMILY SSF103473 572 600 1.44E-68 T 28-03-2018 IPR020846 Major facilitator superfamily domain CO689_RS03760 3abc9697ab2de85b0b21575ef3edcc26 610 SUPERFAMILY SSF103473 349 520 1.44E-68 T 28-03-2018 IPR020846 Major facilitator superfamily domain CO689_RS03760 3abc9697ab2de85b0b21575ef3edcc26 610 SUPERFAMILY SSF103473 98 296 1.44E-68 T 28-03-2018 IPR020846 Major facilitator superfamily domain CO689_RS11605 508a24d11251b4234c8da77296bc7f03 313 Gene3D G3DSA:3.30.2010.10 115 201 2.6E-8 T 28-03-2018 CO689_RS11605 508a24d11251b4234c8da77296bc7f03 313 Pfam PF01435 Peptidase family M48 136 304 4.1E-18 T 28-03-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 CO689_RS08210 95bf17b048a62adb872517068f4266e9 264 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 91 254 6.8E-15 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CO689_RS08210 95bf17b048a62adb872517068f4266e9 264 Gene3D G3DSA:1.10.3720.10 15 264 8.4E-26 T 28-03-2018 CO689_RS08210 95bf17b048a62adb872517068f4266e9 264 TIGRFAM TIGR01097 PhnE: phosphonate ABC transporter, permease protein PhnE 18 263 5.0E-91 T 28-03-2018 IPR005769 ABC transporter, permease PhnE/PtxC GO:0005887|GO:0015604|GO:0015716 CO689_RS08210 95bf17b048a62adb872517068f4266e9 264 SUPERFAMILY SSF161098 68 256 7.19E-35 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CO689_RS03740 97bda6362fba743151763be54e312e15 160 Gene3D G3DSA:3.10.129.10 1 138 4.6E-17 T 28-03-2018 CO689_RS03740 97bda6362fba743151763be54e312e15 160 SUPERFAMILY SSF54637 1 154 6.22E-33 T 28-03-2018 IPR029069 HotDog domain CO689_RS03740 97bda6362fba743151763be54e312e15 160 Pfam PF13279 Thioesterase-like superfamily 14 129 8.7E-16 T 28-03-2018 CO689_RS07310 b0f3952f4f8bfb23e3002cfcbf12dc60 399 SUPERFAMILY SSF52374 176 387 6.26E-86 T 28-03-2018 CO689_RS07310 b0f3952f4f8bfb23e3002cfcbf12dc60 399 Hamap MF_00066 Sulfate adenylyltransferase [sat]. 35 391 50.838 T 28-03-2018 IPR020792 Sulphate adenylyltransferase, prokaryotic-type GO:0000103|GO:0004781 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 CO689_RS07310 b0f3952f4f8bfb23e3002cfcbf12dc60 399 SUPERFAMILY SSF88697 13 175 6.26E-55 T 28-03-2018 IPR015947 PUA-like domain CO689_RS07310 b0f3952f4f8bfb23e3002cfcbf12dc60 399 Gene3D G3DSA:3.10.400.10 12 185 1.3E-65 T 28-03-2018 CO689_RS07310 b0f3952f4f8bfb23e3002cfcbf12dc60 399 Gene3D G3DSA:3.40.50.620 186 399 2.7E-92 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CO689_RS07310 b0f3952f4f8bfb23e3002cfcbf12dc60 399 Pfam PF14306 PUA-like domain 13 170 1.2E-57 T 28-03-2018 IPR025980 ATP-sulfurylase PUA-like domain KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 CO689_RS07310 b0f3952f4f8bfb23e3002cfcbf12dc60 399 Pfam PF01747 ATP-sulfurylase 178 387 3.1E-96 T 28-03-2018 IPR024951 Sulphate adenylyltransferase catalytic domain GO:0004781 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 CO689_RS07310 b0f3952f4f8bfb23e3002cfcbf12dc60 399 TIGRFAM TIGR00339 sopT: sulfate adenylyltransferase 14 386 3.8E-145 T 28-03-2018 IPR002650 Sulphate adenylyltransferase GO:0000103|GO:0004781 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 CO689_RS13650 6a9ec8675d3e01debd9af60e376c4ee6 184 Gene3D G3DSA:3.40.140.10 99 182 9.8E-29 T 28-03-2018 CO689_RS13650 6a9ec8675d3e01debd9af60e376c4ee6 184 ProSitePatterns PS01302 Uncharacterized protein family UPF0758 signature. 173 178 - T 28-03-2018 IPR020891 Uncharacterised protein family UPF0758, conserved site CO689_RS13650 6a9ec8675d3e01debd9af60e376c4ee6 184 SUPERFAMILY SSF47781 18 90 1.02E-5 T 28-03-2018 IPR010994 RuvA domain 2-like CO689_RS13650 6a9ec8675d3e01debd9af60e376c4ee6 184 TIGRFAM TIGR00608 radc: DNA repair protein RadC 11 179 3.6E-54 T 28-03-2018 IPR001405 RadC protein CO689_RS13650 6a9ec8675d3e01debd9af60e376c4ee6 184 Pfam PF04002 RadC-like JAB domain 103 180 8.5E-27 T 28-03-2018 IPR025657 RadC-like JAB domain CO689_RS04800 5ac2755efa6190db8261cd9020635072 453 SUPERFAMILY SSF51556 54 383 1.97E-89 T 28-03-2018 IPR032466 Metal-dependent hydrolase CO689_RS04800 5ac2755efa6190db8261cd9020635072 453 Hamap MF_01645 Allantoinase [allB]. 2 453 51.697 T 28-03-2018 IPR017593 Allantoinase GO:0000256|GO:0004038|GO:0008270|GO:0050897 KEGG: 00230+3.5.2.5|MetaCyc: PWY-5697|MetaCyc: PWY-5698 CO689_RS04800 5ac2755efa6190db8261cd9020635072 453 Gene3D G3DSA:2.30.40.10 1 58 2.4E-17 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CO689_RS04800 5ac2755efa6190db8261cd9020635072 453 SUPERFAMILY SSF51338 383 451 2.52E-27 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CO689_RS04800 5ac2755efa6190db8261cd9020635072 453 SUPERFAMILY SSF51338 3 53 2.52E-27 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CO689_RS04800 5ac2755efa6190db8261cd9020635072 453 TIGRFAM TIGR03178 allantoinase: allantoinase 4 453 7.5E-193 T 28-03-2018 IPR017593 Allantoinase GO:0000256|GO:0004038|GO:0008270|GO:0050897 KEGG: 00230+3.5.2.5|MetaCyc: PWY-5697|MetaCyc: PWY-5698 CO689_RS04800 5ac2755efa6190db8261cd9020635072 453 Pfam PF01979 Amidohydrolase family 50 435 2.2E-21 T 28-03-2018 IPR006680 Amidohydrolase-related GO:0016787 CO689_RS04800 5ac2755efa6190db8261cd9020635072 453 Gene3D G3DSA:3.20.20.140 59 429 5.2E-93 T 28-03-2018 CO689_RS06310 4db790e5162ab1493b544ec66b64985f 176 Gene3D G3DSA:1.10.357.10 2 174 2.0E-26 T 28-03-2018 CO689_RS06310 4db790e5162ab1493b544ec66b64985f 176 SUPERFAMILY SSF48498 102 173 3.34E-13 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CO689_RS06310 4db790e5162ab1493b544ec66b64985f 176 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 31 54 1.8E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CO689_RS06310 4db790e5162ab1493b544ec66b64985f 176 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 10 23 1.8E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CO689_RS06310 4db790e5162ab1493b544ec66b64985f 176 SUPERFAMILY SSF46689 3 73 3.85E-16 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CO689_RS06310 4db790e5162ab1493b544ec66b64985f 176 Pfam PF00440 Bacterial regulatory proteins, tetR family 10 54 7.2E-12 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CO689_RS10635 37ddc88ef1ac4579de4b327926bb7138 303 SUPERFAMILY SSF51569 3 301 1.25E-60 T 28-03-2018 CO689_RS10635 37ddc88ef1ac4579de4b327926bb7138 303 Gene3D G3DSA:3.20.20.70 1 303 1.6E-73 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CO689_RS10635 37ddc88ef1ac4579de4b327926bb7138 303 TIGRFAM TIGR01232 lacD: tagatose 1,6-diphosphate aldolase 4 302 3.4E-136 T 28-03-2018 IPR005927 Tagatose 1,6-diphosphate aldolase GO:0009024|GO:0019512 KEGG: 00052+4.1.2.40|MetaCyc: PWY-7077|MetaCyc: PWY-7395 CO689_RS10635 37ddc88ef1ac4579de4b327926bb7138 303 SMART SM01133 7 264 8.8E-29 T 28-03-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 CO689_RS10635 37ddc88ef1ac4579de4b327926bb7138 303 Pfam PF01791 DeoC/LacD family aldolase 7 263 7.6E-64 T 28-03-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 CO689_RS10635 37ddc88ef1ac4579de4b327926bb7138 303 Hamap MF_00734 Tagatose 1,6-diphosphate aldolase [lacD]. 1 303 174.935 T 28-03-2018 IPR005927 Tagatose 1,6-diphosphate aldolase GO:0009024|GO:0019512 KEGG: 00052+4.1.2.40|MetaCyc: PWY-7077|MetaCyc: PWY-7395 CO689_RS02525 4fa4d244459e1b56c0363ba417e57fab 199 Hamap MF_00124 Thymidine kinase [tdk]. 7 190 37.327 T 28-03-2018 IPR001267 Thymidine kinase GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-539107|Reactome: R-HSA-73614 CO689_RS02525 4fa4d244459e1b56c0363ba417e57fab 199 SUPERFAMILY SSF52540 8 142 1.23E-42 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CO689_RS02525 4fa4d244459e1b56c0363ba417e57fab 199 Gene3D G3DSA:3.30.60.20 142 199 5.7E-19 T 28-03-2018 CO689_RS02525 4fa4d244459e1b56c0363ba417e57fab 199 Gene3D G3DSA:3.40.50.300 7 141 2.2E-47 T 28-03-2018 CO689_RS02525 4fa4d244459e1b56c0363ba417e57fab 199 Pfam PF00265 Thymidine kinase 8 187 2.4E-58 T 28-03-2018 IPR001267 Thymidine kinase GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-539107|Reactome: R-HSA-73614 CO689_RS02525 4fa4d244459e1b56c0363ba417e57fab 199 SUPERFAMILY SSF57716 142 193 1.24E-15 T 28-03-2018 CO689_RS02525 4fa4d244459e1b56c0363ba417e57fab 199 PIRSF PIRSF035805 5 199 1.5E-66 T 28-03-2018 IPR001267 Thymidine kinase GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-539107|Reactome: R-HSA-73614 CO689_RS02525 4fa4d244459e1b56c0363ba417e57fab 199 ProSitePatterns PS00603 Thymidine kinase cellular-type signature. 174 187 - T 28-03-2018 IPR020633 Thymidine kinase, conserved site GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-539107|Reactome: R-HSA-73614 CO689_RS05970 77e99660b255cd5807a74374679aa5d3 90 SUPERFAMILY SSF55729 3 83 4.12E-22 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CO689_RS05970 77e99660b255cd5807a74374679aa5d3 90 Pfam PF14542 GCN5-related N-acetyl-transferase 10 82 3.3E-21 T 28-03-2018 IPR031165 Yjdj-type Gcn5-related N-acetyltransferase CO689_RS05970 77e99660b255cd5807a74374679aa5d3 90 Gene3D G3DSA:3.40.630.30 2 90 5.9E-15 T 28-03-2018 CO689_RS00480 36549288f7bf35f192f1ab571cf91c4d 167 Pfam PF03780 Asp23 family, cell envelope-related function 38 143 5.3E-33 T 28-03-2018 IPR005531 Alkaline shock protein Asp23 CO689_RS10220 67c68ef81e6d07c00d962c46acfae522 239 Hamap MF_01124 Adapter protein MecA [mecA]. 1 233 24.552 T 28-03-2018 IPR008681 Negative regulator of genetic competence, MecA CO689_RS10220 67c68ef81e6d07c00d962c46acfae522 239 PIRSF PIRSF029008 1 235 7.2E-65 T 28-03-2018 IPR008681 Negative regulator of genetic competence, MecA CO689_RS10220 67c68ef81e6d07c00d962c46acfae522 239 Pfam PF05389 Negative regulator of genetic competence (MecA) 1 228 3.5E-51 T 28-03-2018 IPR008681 Negative regulator of genetic competence, MecA CO689_RS01760 db92f20f6e136b8fdbb3f2c8936b1681 438 Gene3D G3DSA:3.40.1190.10 46 297 3.8E-42 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CO689_RS01760 db92f20f6e136b8fdbb3f2c8936b1681 438 SUPERFAMILY SSF53623 50 190 3.43E-32 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CO689_RS01760 db92f20f6e136b8fdbb3f2c8936b1681 438 SUPERFAMILY SSF53623 235 292 3.43E-32 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CO689_RS01760 db92f20f6e136b8fdbb3f2c8936b1681 438 Pfam PF08245 Mur ligase middle domain 53 274 3.5E-18 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CO689_RS01760 db92f20f6e136b8fdbb3f2c8936b1681 438 Pfam PF08353 Domain of unknown function (DUF1727) 313 421 1.5E-28 T 28-03-2018 IPR013564 Domain of unknown function DUF1727 CO689_RS01760 db92f20f6e136b8fdbb3f2c8936b1681 438 Gene3D G3DSA:3.90.190.20 298 415 0.0026 T 28-03-2018 CO689_RS10195 0f5b426cf45d415d933029adcfd126df 203 SUPERFAMILY SSF55729 13 200 1.95E-24 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CO689_RS10195 0f5b426cf45d415d933029adcfd126df 203 Gene3D G3DSA:3.40.630.30 10 201 8.4E-22 T 28-03-2018 CO689_RS10195 0f5b426cf45d415d933029adcfd126df 203 Pfam PF13673 Acetyltransferase (GNAT) domain 108 189 2.1E-15 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CO689_RS03895 1da2e19d9fdcfe34af6888171dab1a76 208 Pfam PF00881 Nitroreductase family 11 188 1.4E-30 T 28-03-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 CO689_RS03895 1da2e19d9fdcfe34af6888171dab1a76 208 SUPERFAMILY SSF55469 7 204 5.1E-55 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CO689_RS03895 1da2e19d9fdcfe34af6888171dab1a76 208 Gene3D G3DSA:3.40.109.10 1 208 1.9E-43 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CO689_RS12055 4b04825510834e78574c6c8be590d041 64 Gene3D G3DSA:1.10.3470.10 6 63 3.6E-4 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CO689_RS07515 16342ed8c6bf41f7cc962b6e5489c67f 393 Gene3D G3DSA:1.20.1250.20 195 393 4.9E-26 T 28-03-2018 CO689_RS07515 16342ed8c6bf41f7cc962b6e5489c67f 393 Gene3D G3DSA:1.20.1250.20 1 194 5.9E-30 T 28-03-2018 CO689_RS07515 16342ed8c6bf41f7cc962b6e5489c67f 393 Pfam PF07690 Major Facilitator Superfamily 14 273 2.3E-31 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CO689_RS07515 16342ed8c6bf41f7cc962b6e5489c67f 393 SUPERFAMILY SSF103473 6 388 1.57E-57 T 28-03-2018 IPR020846 Major facilitator superfamily domain CO689_RS00180 c977e5096413a8f606b167f1016495ec 390 SUPERFAMILY SSF103473 9 377 1.57E-56 T 28-03-2018 IPR020846 Major facilitator superfamily domain CO689_RS00180 c977e5096413a8f606b167f1016495ec 390 Gene3D G3DSA:1.20.1250.20 3 189 7.8E-23 T 28-03-2018 CO689_RS00180 c977e5096413a8f606b167f1016495ec 390 Pfam PF07690 Major Facilitator Superfamily 14 349 1.5E-41 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CO689_RS00180 c977e5096413a8f606b167f1016495ec 390 Gene3D G3DSA:1.20.1250.20 195 382 3.0E-25 T 28-03-2018 CO689_RS03905 cd03d0833c795f20dc394a446fa5249a 134 SUPERFAMILY SSF49764 16 132 3.98E-30 T 28-03-2018 IPR008978 HSP20-like chaperone CO689_RS03905 cd03d0833c795f20dc394a446fa5249a 134 Gene3D G3DSA:2.60.40.790 2 134 4.0E-30 T 28-03-2018 IPR008978 HSP20-like chaperone CO689_RS03905 cd03d0833c795f20dc394a446fa5249a 134 Pfam PF00011 Hsp20/alpha crystallin family 31 133 8.9E-20 T 28-03-2018 IPR002068 Alpha crystallin/Hsp20 domain CO689_RS01805 965208c231a05af8eeddb91b3236b0b9 347 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 29 319 3.5E-18 T 28-03-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 CO689_RS01805 965208c231a05af8eeddb91b3236b0b9 347 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 122 294 5.7E-49 T 28-03-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 CO689_RS01805 965208c231a05af8eeddb91b3236b0b9 347 Gene3D G3DSA:3.40.50.720 9 140 5.5E-32 T 28-03-2018 CO689_RS01805 965208c231a05af8eeddb91b3236b0b9 347 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 234 250 - T 28-03-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site CO689_RS01805 965208c231a05af8eeddb91b3236b0b9 347 Gene3D G3DSA:3.40.50.720 141 296 1.2E-37 T 28-03-2018 CO689_RS01805 965208c231a05af8eeddb91b3236b0b9 347 SUPERFAMILY SSF52283 23 137 2.55E-38 T 28-03-2018 CO689_RS01805 965208c231a05af8eeddb91b3236b0b9 347 SUPERFAMILY SSF51735 115 295 1.54E-48 T 28-03-2018 IPR016040 NAD(P)-binding domain CO689_RS03630 277cb1a3e808bae33616b3bf152a163c 413 SUPERFAMILY SSF51556 71 362 6.56E-72 T 28-03-2018 IPR032466 Metal-dependent hydrolase CO689_RS03630 277cb1a3e808bae33616b3bf152a163c 413 SUPERFAMILY SSF51338 4 69 2.88E-15 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CO689_RS03630 277cb1a3e808bae33616b3bf152a163c 413 TIGRFAM TIGR01224 hutI: imidazolonepropionase 35 402 2.3E-131 T 28-03-2018 IPR005920 Imidazolonepropionase GO:0005737|GO:0016812|GO:0019556 KEGG: 00340+3.5.2.7|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 CO689_RS03630 277cb1a3e808bae33616b3bf152a163c 413 Gene3D G3DSA:2.30.40.10 5 86 5.6E-18 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CO689_RS03630 277cb1a3e808bae33616b3bf152a163c 413 Hamap MF_00372 Imidazolonepropionase [hutI]. 4 404 40.421 T 28-03-2018 IPR005920 Imidazolonepropionase GO:0005737|GO:0016812|GO:0019556 KEGG: 00340+3.5.2.7|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 CO689_RS03630 277cb1a3e808bae33616b3bf152a163c 413 Gene3D G3DSA:3.20.20.140 87 363 8.7E-49 T 28-03-2018 CO689_RS03630 277cb1a3e808bae33616b3bf152a163c 413 Pfam PF07969 Amidohydrolase family 101 402 2.5E-13 T 28-03-2018 IPR013108 Amidohydrolase 3 CO689_RS03630 277cb1a3e808bae33616b3bf152a163c 413 SUPERFAMILY SSF51338 350 405 1.38E-14 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CO689_RS02900 89d36be4aec37cef3179895bbe6b4754 337 SUPERFAMILY SSF51735 115 277 2.2E-30 T 28-03-2018 IPR016040 NAD(P)-binding domain CO689_RS02900 89d36be4aec37cef3179895bbe6b4754 337 Pfam PF00107 Zinc-binding dehydrogenase 160 259 1.2E-13 T 28-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CO689_RS02900 89d36be4aec37cef3179895bbe6b4754 337 Gene3D G3DSA:3.90.180.10 1 156 2.0E-38 T 28-03-2018 CO689_RS02900 89d36be4aec37cef3179895bbe6b4754 337 SUPERFAMILY SSF50129 16 140 2.89E-30 T 28-03-2018 IPR011032 GroES-like CO689_RS02900 89d36be4aec37cef3179895bbe6b4754 337 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 31 88 7.6E-7 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CO689_RS02900 89d36be4aec37cef3179895bbe6b4754 337 SMART SM00829 15 332 8.5E-11 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CO689_RS02900 89d36be4aec37cef3179895bbe6b4754 337 TIGRFAM TIGR02817 adh_fam_1: zinc-binding alcohol dehydrogenase family protein 2 333 4.6E-91 T 28-03-2018 IPR014182 Alcohol dehydrogenase, zinc-binding type 1 GO:0008270 CO689_RS02900 89d36be4aec37cef3179895bbe6b4754 337 Gene3D G3DSA:3.40.50.720 157 266 1.4E-18 T 28-03-2018 CO689_RS01035 e41bcd35aad0d7738255ba4c448eb230 263 Gene3D G3DSA:3.90.1200.10 29 257 5.3E-20 T 28-03-2018 CO689_RS01035 e41bcd35aad0d7738255ba4c448eb230 263 SUPERFAMILY SSF56112 2 228 2.82E-27 T 28-03-2018 IPR011009 Protein kinase-like domain CO689_RS01035 e41bcd35aad0d7738255ba4c448eb230 263 Pfam PF01636 Phosphotransferase enzyme family 22 211 1.1E-17 T 28-03-2018 IPR002575 Aminoglycoside phosphotransferase CO689_RS08645 218cc9c07859000f10d493ef1c37db1a 254 Pfam PF06386 Gas vesicle synthesis protein GvpL/GvpF 7 246 1.3E-56 T 28-03-2018 IPR009430 Gas vesicle protein GvpL/GvpF GO:0031411|GO:0031412 CO689_RS09460 19ef4a6ecae932bfc1c30cdc951931c3 120 SUPERFAMILY SSF110455 2 112 1.44E-32 T 28-03-2018 CO689_RS09460 19ef4a6ecae932bfc1c30cdc951931c3 120 Gene3D G3DSA:3.40.1360.20 1 117 3.1E-14 T 28-03-2018 CO689_RS09460 19ef4a6ecae932bfc1c30cdc951931c3 120 SMART SM00493 5 79 7.0E-8 T 28-03-2018 IPR006171 TOPRIM domain CO689_RS08700 e339bf9e199146581f0ee9fbbf108ef1 162 Pfam PF04306 Protein of unknown function (DUF456) 23 158 4.2E-37 T 28-03-2018 IPR007403 Protein of unknown function DUF456 CO689_RS04510 07bcf4f92fb4509522f15fcdeba2bea8 289 Pfam PF03881 Fructosamine kinase 13 285 1.9E-71 T 28-03-2018 IPR016477 Fructosamine/Ketosamine-3-kinase Reactome: R-HSA-163841 CO689_RS04510 07bcf4f92fb4509522f15fcdeba2bea8 289 Gene3D G3DSA:3.90.1200.10 87 289 6.7E-18 T 28-03-2018 CO689_RS04510 07bcf4f92fb4509522f15fcdeba2bea8 289 PIRSF PIRSF006221 1 288 1.8E-79 T 28-03-2018 IPR016477 Fructosamine/Ketosamine-3-kinase Reactome: R-HSA-163841 CO689_RS04510 07bcf4f92fb4509522f15fcdeba2bea8 289 SUPERFAMILY SSF56112 11 277 4.23E-41 T 28-03-2018 IPR011009 Protein kinase-like domain CO689_RS04510 07bcf4f92fb4509522f15fcdeba2bea8 289 Gene3D G3DSA:3.30.200.20 5 86 3.2E-17 T 28-03-2018 CO689_RS11765 3e3f7291360d27eaddc8817132b07fa6 399 PIRSF PIRSF006078 1 381 4.0E-109 T 28-03-2018 IPR004381 Glycerate kinase GO:0008887|GO:0031388 CO689_RS11765 3e3f7291360d27eaddc8817132b07fa6 399 SUPERFAMILY SSF110738 1 378 5.36E-115 T 28-03-2018 IPR004381 Glycerate kinase GO:0008887|GO:0031388 CO689_RS11765 3e3f7291360d27eaddc8817132b07fa6 399 Pfam PF02595 Glycerate kinase family 3 376 1.9E-125 T 28-03-2018 IPR004381 Glycerate kinase GO:0008887|GO:0031388 CO689_RS11765 3e3f7291360d27eaddc8817132b07fa6 399 TIGRFAM TIGR00045 TIGR00045: glycerate kinase 2 378 1.9E-130 T 28-03-2018 IPR004381 Glycerate kinase GO:0008887|GO:0031388 CO689_RS11765 3e3f7291360d27eaddc8817132b07fa6 399 Gene3D G3DSA:3.90.1510.10 42 279 2.2E-75 T 28-03-2018 IPR018193 Glycerate kinase, flavodoxin-like domain GO:0008887|GO:0031388 CO689_RS07935 03f6d5a42848c0d31be6e7d2952a02b5 403 Pfam PF01773 Na+ dependent nucleoside transporter N-terminus 8 80 1.7E-19 T 28-03-2018 IPR002668 Concentrative nucleoside transporter N-terminal domain Reactome: R-HSA-83936 CO689_RS07935 03f6d5a42848c0d31be6e7d2952a02b5 403 Pfam PF07662 Na+ dependent nucleoside transporter C-terminus 194 402 3.2E-62 T 28-03-2018 IPR011657 Concentrative nucleoside transporter C-terminal domain Reactome: R-HSA-83936 CO689_RS07935 03f6d5a42848c0d31be6e7d2952a02b5 403 Pfam PF07670 Nucleoside recognition 93 190 1.9E-5 T 28-03-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 CO689_RS12830 8e2a5c152cfd55b47d67c0ee72967305 328 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 5 27 8.4E-18 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CO689_RS12830 8e2a5c152cfd55b47d67c0ee72967305 328 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 211 227 8.4E-18 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CO689_RS12830 8e2a5c152cfd55b47d67c0ee72967305 328 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 287 305 8.4E-18 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CO689_RS12830 8e2a5c152cfd55b47d67c0ee72967305 328 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 119 127 8.4E-18 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CO689_RS12830 8e2a5c152cfd55b47d67c0ee72967305 328 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 154 178 8.4E-18 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CO689_RS12830 8e2a5c152cfd55b47d67c0ee72967305 328 Gene3D G3DSA:3.50.50.60 2 154 3.3E-16 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CO689_RS12830 8e2a5c152cfd55b47d67c0ee72967305 328 Pfam PF13738 Pyridine nucleotide-disulphide oxidoreductase 7 291 2.8E-98 T 28-03-2018 CO689_RS12830 8e2a5c152cfd55b47d67c0ee72967305 328 TIGRFAM TIGR04018 Bthiol_YpdA: putative bacillithiol system oxidoreductase, YpdA family 6 320 1.0E-137 T 28-03-2018 IPR023856 Bacillithiol biosynthesis thiol disulphide oxidoreductase, YpdA CO689_RS12830 8e2a5c152cfd55b47d67c0ee72967305 328 SUPERFAMILY SSF51905 7 320 1.09E-37 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CO689_RS12830 8e2a5c152cfd55b47d67c0ee72967305 328 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 1.2E-12 T 28-03-2018 CO689_RS12830 8e2a5c152cfd55b47d67c0ee72967305 328 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 158 176 1.2E-12 T 28-03-2018 CO689_RS12830 8e2a5c152cfd55b47d67c0ee72967305 328 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 272 294 1.2E-12 T 28-03-2018 CO689_RS12830 8e2a5c152cfd55b47d67c0ee72967305 328 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 241 257 1.2E-12 T 28-03-2018 CO689_RS12830 8e2a5c152cfd55b47d67c0ee72967305 328 Gene3D G3DSA:3.50.50.60 156 326 8.8E-23 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CO689_RS08840 416c27da561f47b1bbe1b13f45ddb726 142 Pfam PF10517 Electron transfer DM13 52 140 9.9E-14 T 28-03-2018 IPR019545 DM13 domain CO689_RS13780 dbe437549f61f0c4ac23d9896bd6b459 476 Pfam PF07261 Replication initiation and membrane attachment 326 389 1.6E-10 T 28-03-2018 IPR006343 DnaD domain CO689_RS13780 dbe437549f61f0c4ac23d9896bd6b459 476 Gene3D G3DSA:1.10.10.630 318 391 1.3E-11 T 28-03-2018 IPR034829 DnaD-like domain CO689_RS02120 a1d54373326ae5a2fce5b33c6fac4652 433 Gene3D G3DSA:3.30.565.10 275 408 1.7E-13 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CO689_RS02120 a1d54373326ae5a2fce5b33c6fac4652 433 Pfam PF14501 GHKL domain 322 424 2.9E-18 T 28-03-2018 IPR032834 Sensor histidine kinase NatK, C-terminal domain CO689_RS02120 a1d54373326ae5a2fce5b33c6fac4652 433 Gene3D G3DSA:1.10.287.130 208 271 6.9E-8 T 28-03-2018 CO689_RS02120 a1d54373326ae5a2fce5b33c6fac4652 433 SUPERFAMILY SSF55874 290 405 4.89E-12 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CO689_RS10580 30ea7bff48c39f7f9404e42169f395dd 305 SUPERFAMILY SSF103481 195 301 1.09E-12 T 28-03-2018 CO689_RS10580 30ea7bff48c39f7f9404e42169f395dd 305 SUPERFAMILY SSF103481 45 152 3.4E-12 T 28-03-2018 CO689_RS10580 30ea7bff48c39f7f9404e42169f395dd 305 Pfam PF00892 EamA-like transporter family 12 150 1.3E-16 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CO689_RS10580 30ea7bff48c39f7f9404e42169f395dd 305 Pfam PF00892 EamA-like transporter family 161 297 3.6E-19 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CO689_RS01860 cdc09e5b6e97787c90ff5b7cd838d431 359 Pfam PF02898 Nitric oxide synthase, oxygenase domain 2 351 7.8E-148 T 28-03-2018 IPR004030 Nitric oxide synthase, N-terminal GO:0004517|GO:0006809|GO:0055114 Reactome: R-HSA-1222556|Reactome: R-HSA-392154 CO689_RS01860 cdc09e5b6e97787c90ff5b7cd838d431 359 Gene3D G3DSA:3.90.340.10 1 119 1.7E-41 T 28-03-2018 CO689_RS01860 cdc09e5b6e97787c90ff5b7cd838d431 359 ProSitePatterns PS60001 Nitric oxide synthase (NOS) signature. 61 68 - T 28-03-2018 IPR004030 Nitric oxide synthase, N-terminal GO:0004517|GO:0006809|GO:0055114 Reactome: R-HSA-1222556|Reactome: R-HSA-392154 CO689_RS01860 cdc09e5b6e97787c90ff5b7cd838d431 359 Gene3D G3DSA:3.90.1230.10 184 294 4.1E-44 T 28-03-2018 CO689_RS01860 cdc09e5b6e97787c90ff5b7cd838d431 359 PIRSF PIRSF037219 1 359 1.6E-143 T 28-03-2018 IPR017142 Nitric oxide synthase, oxygenase subunit GO:0004517|GO:0006809|GO:0020037 KEGG: 00220+1.14.13.165|KEGG: 00330+1.14.13.165 CO689_RS01860 cdc09e5b6e97787c90ff5b7cd838d431 359 SUPERFAMILY SSF56512 2 352 1.31E-148 T 28-03-2018 IPR004030 Nitric oxide synthase, N-terminal GO:0004517|GO:0006809|GO:0055114 Reactome: R-HSA-1222556|Reactome: R-HSA-392154 CO689_RS05560 67a9716ca5969797a79f48543f46cfa4 308 Gene3D G3DSA:1.20.1250.20 93 255 2.3E-5 T 28-03-2018 CO689_RS05560 67a9716ca5969797a79f48543f46cfa4 308 Pfam PF04657 Putative inner membrane exporter, YdcZ 4 143 1.5E-33 T 28-03-2018 IPR006750 Putative inner membrane exporter, YdcZ CO689_RS05560 67a9716ca5969797a79f48543f46cfa4 308 Pfam PF04657 Putative inner membrane exporter, YdcZ 163 304 3.6E-41 T 28-03-2018 IPR006750 Putative inner membrane exporter, YdcZ CO689_RS10670 73e4f57976d73f4ce0a9c3b616a55f25 302 Pfam PF01156 Inosine-uridine preferring nucleoside hydrolase 4 291 1.2E-85 T 28-03-2018 IPR001910 Inosine/uridine-preferring nucleoside hydrolase domain CO689_RS10670 73e4f57976d73f4ce0a9c3b616a55f25 302 SUPERFAMILY SSF53590 3 299 7.98E-92 T 28-03-2018 IPR001910 Inosine/uridine-preferring nucleoside hydrolase domain CO689_RS10670 73e4f57976d73f4ce0a9c3b616a55f25 302 Gene3D G3DSA:3.90.245.10 1 302 1.9E-98 T 28-03-2018 IPR001910 Inosine/uridine-preferring nucleoside hydrolase domain CO689_RS11145 90faaefe519f6883f6a69313fa8e0c8b 219 SMART SM00479 54 219 1.1E-13 T 28-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III CO689_RS11145 90faaefe519f6883f6a69313fa8e0c8b 219 Gene3D G3DSA:3.30.420.10 45 219 2.4E-29 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CO689_RS11145 90faaefe519f6883f6a69313fa8e0c8b 219 Pfam PF00929 Exonuclease 60 208 4.8E-18 T 28-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III CO689_RS11145 90faaefe519f6883f6a69313fa8e0c8b 219 SUPERFAMILY SSF53098 53 215 4.66E-33 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CO689_RS01695 f39613203e0e08c75428ffcdd35105b6 412 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 303 323 1.0E-51 T 28-03-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 CO689_RS01695 f39613203e0e08c75428ffcdd35105b6 412 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 247 266 1.0E-51 T 28-03-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 CO689_RS01695 f39613203e0e08c75428ffcdd35105b6 412 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 391 410 1.0E-51 T 28-03-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 CO689_RS01695 f39613203e0e08c75428ffcdd35105b6 412 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 365 387 1.0E-51 T 28-03-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 CO689_RS01695 f39613203e0e08c75428ffcdd35105b6 412 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 15 32 1.0E-51 T 28-03-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 CO689_RS01695 f39613203e0e08c75428ffcdd35105b6 412 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 158 180 1.0E-51 T 28-03-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 CO689_RS01695 f39613203e0e08c75428ffcdd35105b6 412 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 326 347 1.0E-51 T 28-03-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 CO689_RS01695 f39613203e0e08c75428ffcdd35105b6 412 SUPERFAMILY SSF144052 5 411 5.49E-143 T 28-03-2018 CO689_RS01695 f39613203e0e08c75428ffcdd35105b6 412 Gene3D G3DSA:3.40.1830.10 5 177 1.3E-54 T 28-03-2018 IPR035097 Peptidase M29, N-terminal CO689_RS01695 f39613203e0e08c75428ffcdd35105b6 412 Pfam PF02073 Thermophilic metalloprotease (M29) 5 410 5.2E-164 T 28-03-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 CO689_RS03290 264bbbedb32509e1993019a978ba565e 151 SUPERFAMILY SSF54690 4 140 2.48E-45 T 28-03-2018 IPR003448 Molybdopterin biosynthesis MoaE GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|Reactome: R-HSA-947581 CO689_RS03290 264bbbedb32509e1993019a978ba565e 151 Pfam PF02391 MoaE protein 8 117 4.1E-36 T 28-03-2018 IPR003448 Molybdopterin biosynthesis MoaE GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|Reactome: R-HSA-947581 CO689_RS03290 264bbbedb32509e1993019a978ba565e 151 Gene3D G3DSA:3.90.1170.40 1 147 7.9E-47 T 28-03-2018 IPR003448 Molybdopterin biosynthesis MoaE GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|Reactome: R-HSA-947581 CO689_RS02330 62261f8f5d6dc60bff6616e14d7f07a1 438 Pfam PF01610 Transposase 164 417 4.8E-62 T 28-03-2018 IPR002560 Transposase IS204/IS1001/IS1096/IS1165, DDE domain CO689_RS02330 62261f8f5d6dc60bff6616e14d7f07a1 438 Pfam PF14690 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 43 92 1.0E-5 T 28-03-2018 IPR029261 Transposase IS204/IS1001/IS1096/IS1165, zinc-finger CO689_RS02330 62261f8f5d6dc60bff6616e14d7f07a1 438 Pfam PF13542 Helix-turn-helix domain of transposase family ISL3 98 147 6.0E-7 T 28-03-2018 IPR032877 Transposase IS204/IS1001/IS1096/IS1165, helix-turn-helix domain CO689_RS02330 62261f8f5d6dc60bff6616e14d7f07a1 438 Gene3D G3DSA:1.10.10.10 108 156 0.0022 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS10955 209846317aeb17d013cc14f0f78b325b 91 Hamap MF_01560 UPF0358 protein . 1 91 24.657 T 28-03-2018 IPR009983 Uncharacterised protein family UPF0358 CO689_RS10955 209846317aeb17d013cc14f0f78b325b 91 Gene3D G3DSA:1.10.287.750 6 88 1.2E-38 T 28-03-2018 CO689_RS10955 209846317aeb17d013cc14f0f78b325b 91 Pfam PF07408 Protein of unknown function (DUF1507) 8 89 1.5E-37 T 28-03-2018 IPR009983 Uncharacterised protein family UPF0358 CO689_RS10955 209846317aeb17d013cc14f0f78b325b 91 SUPERFAMILY SSF140404 6 82 2.35E-33 T 28-03-2018 IPR009983 Uncharacterised protein family UPF0358 CO689_RS12290 80f1c76d73e2097a422a1c80df07e745 172 Pfam PF01625 Peptide methionine sulfoxide reductase 5 156 6.1E-60 T 28-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 CO689_RS12290 80f1c76d73e2097a422a1c80df07e745 172 Hamap MF_01401 Peptide methionine sulfoxide reductase MsrA [msrA]. 3 162 35.906 T 28-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 CO689_RS12290 80f1c76d73e2097a422a1c80df07e745 172 TIGRFAM TIGR00401 msrA: peptide-methionine (S)-S-oxide reductase 5 155 1.7E-56 T 28-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 CO689_RS12290 80f1c76d73e2097a422a1c80df07e745 172 Gene3D G3DSA:3.30.1060.10 2 172 4.4E-63 T 28-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 CO689_RS12290 80f1c76d73e2097a422a1c80df07e745 172 SUPERFAMILY SSF55068 2 156 7.85E-66 T 28-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 CO689_RS13480 60e69764cb0e5983c1b0c659da890d7e 258 Gene3D G3DSA:3.40.50.720 1 251 1.3E-41 T 28-03-2018 CO689_RS13480 60e69764cb0e5983c1b0c659da890d7e 258 SUPERFAMILY SSF69572 4 246 5.62E-60 T 28-03-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 CO689_RS13480 60e69764cb0e5983c1b0c659da890d7e 258 Pfam PF00899 ThiF family 7 159 7.9E-35 T 28-03-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 CO689_RS00845 be51097e4886767c88f4bf2bf7c11a9d 398 SUPERFAMILY SSF53067 157 394 5.3E-93 T 28-03-2018 CO689_RS00845 be51097e4886767c88f4bf2bf7c11a9d 398 TIGRFAM TIGR00016 ackA: acetate kinase 2 395 4.7E-170 T 28-03-2018 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CO689_RS00845 be51097e4886767c88f4bf2bf7c11a9d 398 PIRSF PIRSF000722 1 397 1.9E-154 T 28-03-2018 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CO689_RS00845 be51097e4886767c88f4bf2bf7c11a9d 398 PRINTS PR00471 Acetate kinase family signature 203 224 2.4E-47 T 28-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CO689_RS00845 be51097e4886767c88f4bf2bf7c11a9d 398 PRINTS PR00471 Acetate kinase family signature 322 338 2.4E-47 T 28-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CO689_RS00845 be51097e4886767c88f4bf2bf7c11a9d 398 PRINTS PR00471 Acetate kinase family signature 300 313 2.4E-47 T 28-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CO689_RS00845 be51097e4886767c88f4bf2bf7c11a9d 398 PRINTS PR00471 Acetate kinase family signature 173 186 2.4E-47 T 28-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CO689_RS00845 be51097e4886767c88f4bf2bf7c11a9d 398 PRINTS PR00471 Acetate kinase family signature 5 16 2.4E-47 T 28-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CO689_RS00845 be51097e4886767c88f4bf2bf7c11a9d 398 PRINTS PR00471 Acetate kinase family signature 377 389 2.4E-47 T 28-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CO689_RS00845 be51097e4886767c88f4bf2bf7c11a9d 398 Gene3D G3DSA:3.30.420.40 4 195 5.3E-79 T 28-03-2018 CO689_RS00845 be51097e4886767c88f4bf2bf7c11a9d 398 SUPERFAMILY SSF53067 3 195 1.04E-71 T 28-03-2018 CO689_RS00845 be51097e4886767c88f4bf2bf7c11a9d 398 ProSitePatterns PS01075 Acetate and butyrate kinases family signature 1. 5 16 - T 28-03-2018 IPR023865 Aliphatic acid kinase, short-chain, conserved site GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CO689_RS00845 be51097e4886767c88f4bf2bf7c11a9d 398 ProSitePatterns PS01076 Acetate and butyrate kinases family signature 2. 203 220 - T 28-03-2018 IPR023865 Aliphatic acid kinase, short-chain, conserved site GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CO689_RS00845 be51097e4886767c88f4bf2bf7c11a9d 398 Gene3D G3DSA:3.30.420.40 196 397 1.0E-82 T 28-03-2018 CO689_RS00845 be51097e4886767c88f4bf2bf7c11a9d 398 Hamap MF_00020 Acetate kinase [ackA]. 1 398 198.343 T 28-03-2018 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CO689_RS00845 be51097e4886767c88f4bf2bf7c11a9d 398 Pfam PF00871 Acetokinase family 5 390 1.2E-166 T 28-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CO689_RS11125 8c53b4607e5f272bf36df528737f14d5 169 Gene3D G3DSA:3.60.21.10 2 168 4.6E-17 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CO689_RS11125 8c53b4607e5f272bf36df528737f14d5 169 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 4 142 3.1E-21 T 28-03-2018 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 CO689_RS11125 8c53b4607e5f272bf36df528737f14d5 169 TIGRFAM TIGR00040 yfcE: phosphodiesterase, MJ0936 family 5 149 9.3E-25 T 28-03-2018 IPR000979 Phosphodiesterase MJ0936/Vps29 Reactome: R-HSA-3238698 CO689_RS11125 8c53b4607e5f272bf36df528737f14d5 169 SUPERFAMILY SSF56300 3 165 1.59E-41 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CO689_RS00960 56dbba36941d487478e51dbfec28ff52 210 Pfam PF00583 Acetyltransferase (GNAT) family 44 121 1.4E-4 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CO689_RS00960 56dbba36941d487478e51dbfec28ff52 210 PIRSF PIRSF021278 2 210 5.3E-99 T 28-03-2018 IPR024699 Acetoin utilization protein AcuA GO:0019152|GO:0045150 CO689_RS00960 56dbba36941d487478e51dbfec28ff52 210 SUPERFAMILY SSF55729 40 121 5.74E-8 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CO689_RS00960 56dbba36941d487478e51dbfec28ff52 210 Gene3D G3DSA:3.40.630.30 1 210 5.8E-49 T 28-03-2018 CO689_RS09005 5d0b09095ee9a82782b3a159fb289b91 319 SUPERFAMILY SSF81345 9 315 3.4E-53 T 28-03-2018 IPR029022 ABC transporter, BtuC-like CO689_RS09005 5d0b09095ee9a82782b3a159fb289b91 319 Gene3D G3DSA:1.10.3470.10 33 319 3.1E-34 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CO689_RS09005 5d0b09095ee9a82782b3a159fb289b91 319 Pfam PF01032 FecCD transport family 38 315 1.4E-48 T 28-03-2018 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 CO689_RS09605 9a1744b450360c2078e770508b2adee2 76 Pfam PF10656 Hypothetical protein of unknown function (DUF2483) 1 75 2.6E-36 T 28-03-2018 IPR018918 Protein of unknown function DUF2483 CO689_RS02245 0e6b3c181dab2c3f571b1b89e21f19a1 150 Pfam PF10263 SprT-like family 7 97 7.5E-14 T 28-03-2018 IPR006640 SprT-like CO689_RS02245 0e6b3c181dab2c3f571b1b89e21f19a1 150 Hamap MF_00745 Protein SprT-like. 4 147 38.928 T 28-03-2018 IPR023524 Uncharacterised protein family SprT-like CO689_RS02245 0e6b3c181dab2c3f571b1b89e21f19a1 150 SMART SM00731 4 147 5.5E-58 T 28-03-2018 IPR006640 SprT-like CO689_RS08490 c21fcc1f5fc230d3a3c47c0de6451b11 363 SUPERFAMILY SSF53756 72 360 2.93E-13 T 28-03-2018 CO689_RS08490 c21fcc1f5fc230d3a3c47c0de6451b11 363 Gene3D G3DSA:3.40.50.2000 188 324 5.5E-5 T 28-03-2018 CO689_RS08490 c21fcc1f5fc230d3a3c47c0de6451b11 363 Pfam PF04464 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase 48 333 5.5E-43 T 28-03-2018 IPR007554 CDP-glycerol glycerophosphotransferase GO:0016020|GO:0047355 CO689_RS09525 fb4e2710fc9c1700e6d3cc12928d5574 349 Pfam PF14659 Phage integrase, N-terminal SAM-like domain 59 114 1.5E-11 T 28-03-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 CO689_RS09525 fb4e2710fc9c1700e6d3cc12928d5574 349 Pfam PF00589 Phage integrase family 174 336 9.1E-21 T 28-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 CO689_RS09525 fb4e2710fc9c1700e6d3cc12928d5574 349 Gene3D G3DSA:1.10.443.10 164 349 1.3E-27 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 CO689_RS09525 fb4e2710fc9c1700e6d3cc12928d5574 349 SUPERFAMILY SSF56349 58 343 2.94E-47 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CO689_RS09525 fb4e2710fc9c1700e6d3cc12928d5574 349 Pfam PF14657 Arm DNA-binding domain 11 54 4.9E-13 T 28-03-2018 IPR028259 AP2-like integrase, N-terminal domain CO689_RS09525 fb4e2710fc9c1700e6d3cc12928d5574 349 Gene3D G3DSA:1.10.150.130 54 163 3.8E-15 T 28-03-2018 IPR023109 Integrase/recombinase, N-terminal CO689_RS05230 60e51b7ee9146f37a68be282d75a99dd 305 Pfam PF01370 NAD dependent epimerase/dehydratase family 4 212 3.9E-17 T 28-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 CO689_RS05230 60e51b7ee9146f37a68be282d75a99dd 305 SUPERFAMILY SSF51735 4 303 2.91E-30 T 28-03-2018 IPR016040 NAD(P)-binding domain CO689_RS05230 60e51b7ee9146f37a68be282d75a99dd 305 Gene3D G3DSA:3.40.50.720 3 305 4.5E-18 T 28-03-2018 CO689_RS10820 367b7c0dbaa4cffaa1e6e81187c302f2 451 Pfam PF01654 Cytochrome bd terminal oxidase subunit I 6 435 3.2E-130 T 28-03-2018 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0009055|GO:0019646|GO:0070069 CO689_RS10820 367b7c0dbaa4cffaa1e6e81187c302f2 451 PIRSF PIRSF006446 1 451 2.0E-135 T 28-03-2018 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0009055|GO:0019646|GO:0070069 CO689_RS02195 90aa46a687e9f57e9efd6550e8ee9d7c 334 SUPERFAMILY SSF48179 183 329 4.42E-69 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CO689_RS02195 90aa46a687e9f57e9efd6550e8ee9d7c 334 TIGRFAM TIGR00465 ilvC: ketol-acid reductoisomerase 15 326 1.3E-132 T 28-03-2018 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 CO689_RS02195 90aa46a687e9f57e9efd6550e8ee9d7c 334 Gene3D G3DSA:3.40.50.720 10 70 7.5E-4 T 28-03-2018 CO689_RS02195 90aa46a687e9f57e9efd6550e8ee9d7c 334 Hamap MF_00435 Ketol-acid reductoisomerase (NADP(+)) [ilvC]. 2 328 44.701 T 28-03-2018 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 CO689_RS02195 90aa46a687e9f57e9efd6550e8ee9d7c 334 Gene3D G3DSA:1.10.1040.10 71 330 8.6E-115 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CO689_RS02195 90aa46a687e9f57e9efd6550e8ee9d7c 334 Pfam PF07991 Acetohydroxy acid isomeroreductase, NADPH-binding domain 15 177 3.4E-75 T 28-03-2018 IPR013116 Acetohydroxy acid isomeroreductase, NADPH-binding domain KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 CO689_RS02195 90aa46a687e9f57e9efd6550e8ee9d7c 334 SUPERFAMILY SSF51735 3 182 1.32E-70 T 28-03-2018 IPR016040 NAD(P)-binding domain CO689_RS02195 90aa46a687e9f57e9efd6550e8ee9d7c 334 Pfam PF01450 Acetohydroxy acid isomeroreductase, catalytic domain 183 325 3.5E-65 T 28-03-2018 IPR000506 Acetohydroxy acid isomeroreductase C-terminal GO:0004455|GO:0009082|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 CO689_RS02195 90aa46a687e9f57e9efd6550e8ee9d7c 334 PIRSF PIRSF000116 202 333 1.7E-15 T 28-03-2018 IPR014359 Ketol-acid reductoisomerase, prokaryotic GO:0004455|GO:0009082|GO:0050661|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 CO689_RS02195 90aa46a687e9f57e9efd6550e8ee9d7c 334 PIRSF PIRSF000116 4 209 2.6E-37 T 28-03-2018 IPR014359 Ketol-acid reductoisomerase, prokaryotic GO:0004455|GO:0009082|GO:0050661|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 CO689_RS06635 6c112e18adfa7b895ffcc656f929c563 222 Gene3D G3DSA:3.40.50.2300 1 121 9.7E-35 T 28-03-2018 CO689_RS06635 6c112e18adfa7b895ffcc656f929c563 222 SUPERFAMILY SSF52172 1 165 4.7E-37 T 28-03-2018 IPR011006 CheY-like superfamily CO689_RS06635 6c112e18adfa7b895ffcc656f929c563 222 SMART SM00448 1 112 3.5E-36 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CO689_RS06635 6c112e18adfa7b895ffcc656f929c563 222 Pfam PF00072 Response regulator receiver domain 3 111 7.6E-28 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CO689_RS06635 6c112e18adfa7b895ffcc656f929c563 222 Pfam PF00486 Transcriptional regulatory protein, C terminal 148 218 3.9E-15 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CO689_RS06635 6c112e18adfa7b895ffcc656f929c563 222 SMART SM00862 145 218 3.1E-16 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CO689_RS06635 6c112e18adfa7b895ffcc656f929c563 222 Gene3D G3DSA:1.10.10.10 122 222 7.5E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS09845 0067bbe20fe1ed4742a1f89649697817 346 Gene3D G3DSA:3.20.20.70 111 342 2.2E-30 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CO689_RS09845 0067bbe20fe1ed4742a1f89649697817 346 Pfam PF01595 Domain of unknown function DUF21 3 179 8.2E-46 T 28-03-2018 IPR002550 Domain of unknown function DUF21 CO689_RS09845 0067bbe20fe1ed4742a1f89649697817 346 SUPERFAMILY SSF54631 182 314 7.45E-26 T 28-03-2018 CO689_RS09845 0067bbe20fe1ed4742a1f89649697817 346 Pfam PF00571 CBS domain 264 313 0.002 T 28-03-2018 IPR000644 CBS domain CO689_RS01000 22f5a8ebf3a93a6cbccd822125b511e4 199 Gene3D G3DSA:3.30.1940.10 22 87 3.3E-23 T 28-03-2018 IPR027855 Domain of unknown function DUF4479 CO689_RS01000 22f5a8ebf3a93a6cbccd822125b511e4 199 SUPERFAMILY SSF50249 90 197 2.69E-32 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CO689_RS01000 22f5a8ebf3a93a6cbccd822125b511e4 199 Pfam PF01588 Putative tRNA binding domain 93 194 2.2E-25 T 28-03-2018 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 CO689_RS01000 22f5a8ebf3a93a6cbccd822125b511e4 199 Pfam PF14794 Domain of unknown function (DUF4479) 21 88 2.0E-22 T 28-03-2018 IPR027855 Domain of unknown function DUF4479 CO689_RS01000 22f5a8ebf3a93a6cbccd822125b511e4 199 Gene3D G3DSA:2.40.50.140 88 199 1.0E-38 T 28-03-2018 CO689_RS12740 e2a21293e07d8b1d2e1c3e39735cd8b3 105 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 23 102 8.7E-21 T 28-03-2018 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core CO689_RS12740 e2a21293e07d8b1d2e1c3e39735cd8b3 105 SUPERFAMILY SSF101386 3 102 8.14E-26 T 28-03-2018 CO689_RS12740 e2a21293e07d8b1d2e1c3e39735cd8b3 105 PIRSF PIRSF029904 1 105 3.3E-51 T 28-03-2018 IPR012359 NTP pyrophosphohydrolase MazG-related, YpjD CO689_RS12740 e2a21293e07d8b1d2e1c3e39735cd8b3 105 Gene3D G3DSA:1.10.3420.10 1 105 9.1E-27 T 28-03-2018 CO689_RS10970 6fd890e8ef3b43124bb10e119861e9d3 308 Hamap MF_01664 Heme A synthase [ctaA]. 3 302 26.949 T 28-03-2018 IPR023755 Heme A synthase, type 1 GO:0006784|GO:0016020|GO:0016627|GO:0055114 CO689_RS10970 6fd890e8ef3b43124bb10e119861e9d3 308 Pfam PF02628 Cytochrome oxidase assembly protein 57 281 8.0E-28 T 28-03-2018 IPR003780 COX15/CtaA family GO:0006784|GO:0016021|GO:0016627|GO:0055114 Reactome: R-HSA-189451 CO689_RS13165 db1a608ac77e873c4fb3d0a1aba06275 201 Pfam PF00081 Iron/manganese superoxide dismutases, alpha-hairpin domain 3 89 3.5E-36 T 28-03-2018 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CO689_RS13165 db1a608ac77e873c4fb3d0a1aba06275 201 Gene3D G3DSA:1.10.287.990 20 89 3.4E-32 T 28-03-2018 CO689_RS13165 db1a608ac77e873c4fb3d0a1aba06275 201 PIRSF PIRSF000349 1 201 4.5E-84 T 28-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CO689_RS13165 db1a608ac77e873c4fb3d0a1aba06275 201 Pfam PF02777 Iron/manganese superoxide dismutases, C-terminal domain 95 194 4.7E-44 T 28-03-2018 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CO689_RS13165 db1a608ac77e873c4fb3d0a1aba06275 201 ProSitePatterns PS00088 Manganese and iron superoxide dismutases signature. 162 169 - T 28-03-2018 IPR019833 Manganese/iron superoxide dismutase, binding site GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CO689_RS13165 db1a608ac77e873c4fb3d0a1aba06275 201 SUPERFAMILY SSF46609 1 90 1.01E-39 T 28-03-2018 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CO689_RS13165 db1a608ac77e873c4fb3d0a1aba06275 201 SUPERFAMILY SSF54719 91 200 6.94E-47 T 28-03-2018 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CO689_RS13165 db1a608ac77e873c4fb3d0a1aba06275 201 PRINTS PR01703 Manganese superoxide dismutase signature 27 40 3.1E-27 T 28-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CO689_RS13165 db1a608ac77e873c4fb3d0a1aba06275 201 PRINTS PR01703 Manganese superoxide dismutase signature 72 85 3.1E-27 T 28-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CO689_RS13165 db1a608ac77e873c4fb3d0a1aba06275 201 PRINTS PR01703 Manganese superoxide dismutase signature 160 172 3.1E-27 T 28-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CO689_RS13165 db1a608ac77e873c4fb3d0a1aba06275 201 PRINTS PR01703 Manganese superoxide dismutase signature 123 131 3.1E-27 T 28-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CO689_RS13165 db1a608ac77e873c4fb3d0a1aba06275 201 PRINTS PR01703 Manganese superoxide dismutase signature 6 17 3.1E-27 T 28-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CO689_RS07950 d153947265df74e210a4f6334ac0ccde 334 Pfam PF00217 ATP:guanido phosphotransferase, C-terminal catalytic domain 52 242 2.6E-66 T 28-03-2018 IPR022414 ATP:guanido phosphotransferase, catalytic domain GO:0016301|GO:0016772 Reactome: R-HSA-71288 CO689_RS07950 d153947265df74e210a4f6334ac0ccde 334 Gene3D G3DSA:3.30.590.10 2 244 4.5E-74 T 28-03-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 CO689_RS07950 d153947265df74e210a4f6334ac0ccde 334 Hamap MF_00602 Protein-arginine kinase [mcsB]. 10 334 33.976 T 28-03-2018 IPR023660 Protein arginine kinase GO:0006950|GO:0016775 CO689_RS07950 d153947265df74e210a4f6334ac0ccde 334 ProSitePatterns PS00112 Phosphagen kinase active site signature. 156 162 - T 28-03-2018 IPR022415 ATP:guanido phosphotransferase active site GO:0016301|GO:0016772 Reactome: R-HSA-71288 CO689_RS07950 d153947265df74e210a4f6334ac0ccde 334 SUPERFAMILY SSF55931 6 257 1.26E-76 T 28-03-2018 CO689_RS02050 68b569690e90c215a6b30ca00ef618cd 113 SUPERFAMILY SSF110849 5 83 1.5E-7 T 28-03-2018 IPR003115 ParB/Sulfiredoxin CO689_RS02050 68b569690e90c215a6b30ca00ef618cd 113 Gene3D G3DSA:3.90.1530.10 1 96 2.5E-6 T 28-03-2018 CO689_RS02050 68b569690e90c215a6b30ca00ef618cd 113 Pfam PF02195 ParB-like nuclease domain 8 79 1.6E-4 T 28-03-2018 IPR003115 ParB/Sulfiredoxin CO689_RS08605 f9d1634ca61596f7fd708c299f54cf1d 130 SUPERFAMILY SSF46785 20 129 2.31E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS08605 f9d1634ca61596f7fd708c299f54cf1d 130 TIGRFAM TIGR01889 Staph_reg_Sar: staphylococcal accessory regulator family 20 129 6.1E-24 T 28-03-2018 IPR010166 Transcriptional regulator SarA/Rot GO:0006355 CO689_RS08605 f9d1634ca61596f7fd708c299f54cf1d 130 Gene3D G3DSA:1.10.10.10 11 130 3.0E-8 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS12445 a75afd42a624576c1656729cfc0f1570 400 ProSitePatterns PS00324 Aspartokinase signature. 5 13 - T 28-03-2018 IPR018042 Aspartate kinase, conserved site GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 CO689_RS12445 a75afd42a624576c1656729cfc0f1570 400 PIRSF PIRSF000726 53 400 1.8E-89 T 28-03-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 CO689_RS12445 a75afd42a624576c1656729cfc0f1570 400 PIRSF PIRSF000726 1 60 7.6E-13 T 28-03-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 CO689_RS12445 a75afd42a624576c1656729cfc0f1570 400 SUPERFAMILY SSF55021 248 322 1.24E-8 T 28-03-2018 CO689_RS12445 a75afd42a624576c1656729cfc0f1570 400 Gene3D G3DSA:3.40.1160.10 1 235 2.9E-53 T 28-03-2018 CO689_RS12445 a75afd42a624576c1656729cfc0f1570 400 SUPERFAMILY SSF53633 2 242 3.93E-60 T 28-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase CO689_RS12445 a75afd42a624576c1656729cfc0f1570 400 Gene3D G3DSA:3.30.70.260 236 328 2.7E-12 T 28-03-2018 CO689_RS12445 a75afd42a624576c1656729cfc0f1570 400 Pfam PF00696 Amino acid kinase family 2 227 4.6E-42 T 28-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase CO689_RS12445 a75afd42a624576c1656729cfc0f1570 400 Pfam PF13840 ACT domain 334 395 5.3E-7 T 28-03-2018 IPR027795 GATS-like ACT domain CO689_RS12445 a75afd42a624576c1656729cfc0f1570 400 TIGRFAM TIGR00657 asp_kinases: aspartate kinase 60 398 6.0E-92 T 28-03-2018 IPR001341 Aspartate kinase domain GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 CO689_RS12445 a75afd42a624576c1656729cfc0f1570 400 Gene3D G3DSA:3.30.70.260 329 399 6.6E-11 T 28-03-2018 CO689_RS12445 a75afd42a624576c1656729cfc0f1570 400 SUPERFAMILY SSF55021 333 399 1.44E-12 T 28-03-2018 CO689_RS07605 47b889486db8a838c74d8c9ed1b950a9 645 SUPERFAMILY SSF53474 270 613 1.02E-43 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CO689_RS07605 47b889486db8a838c74d8c9ed1b950a9 645 Gene3D G3DSA:3.40.50.1820 260 644 2.8E-91 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CO689_RS07605 47b889486db8a838c74d8c9ed1b950a9 645 Pfam PF04650 YSIRK type signal peptide 10 30 1.8E-7 T 28-03-2018 IPR005877 YSIRK Gram-positive signal peptide GO:0016020 CO689_RS07605 47b889486db8a838c74d8c9ed1b950a9 645 TIGRFAM TIGR01168 YSIRK_signal: gram-positive signal peptide, YSIRK family 1 40 7.2E-11 T 28-03-2018 IPR005877 YSIRK Gram-positive signal peptide GO:0016020 CO689_RS09555 88a44e620cddae4e0edaa469fff77867 71 Gene3D G3DSA:1.10.260.40 2 71 7.1E-6 T 28-03-2018 CO689_RS09555 88a44e620cddae4e0edaa469fff77867 71 SUPERFAMILY SSF47413 3 51 4.22E-6 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CO689_RS11420 742f0c1ca950dc58ed0f189c786796ea 210 SUPERFAMILY SSF51735 1 209 1.06E-22 T 28-03-2018 IPR016040 NAD(P)-binding domain CO689_RS11420 742f0c1ca950dc58ed0f189c786796ea 210 Pfam PF13460 NAD(P)H-binding 8 171 3.6E-17 T 28-03-2018 IPR016040 NAD(P)-binding domain CO689_RS11420 742f0c1ca950dc58ed0f189c786796ea 210 Gene3D G3DSA:3.40.50.720 1 180 2.0E-11 T 28-03-2018 CO689_RS11845 40263218ba259dcb64bbc899af9fa510 132 SUPERFAMILY SSF47413 3 76 2.91E-7 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CO689_RS11845 40263218ba259dcb64bbc899af9fa510 132 Pfam PF13413 Helix-turn-helix domain 9 67 1.0E-14 T 28-03-2018 CO689_RS11845 40263218ba259dcb64bbc899af9fa510 132 Gene3D G3DSA:1.10.260.40 1 110 6.8E-11 T 28-03-2018 CO689_RS09300 e39c11c396606d2d8c363d61573fee0f 194 TIGRFAM TIGR00493 clpP: ATP-dependent Clp endopeptidase, proteolytic subunit ClpP 1 191 7.1E-104 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CO689_RS09300 e39c11c396606d2d8c363d61573fee0f 194 Gene3D G3DSA:3.90.226.10 2 194 6.1E-47 T 28-03-2018 CO689_RS09300 e39c11c396606d2d8c363d61573fee0f 194 PRINTS PR00127 Clp protease catalytic subunit P signature 168 187 6.3E-55 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CO689_RS09300 e39c11c396606d2d8c363d61573fee0f 194 PRINTS PR00127 Clp protease catalytic subunit P signature 19 34 6.3E-55 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CO689_RS09300 e39c11c396606d2d8c363d61573fee0f 194 PRINTS PR00127 Clp protease catalytic subunit P signature 59 79 6.3E-55 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CO689_RS09300 e39c11c396606d2d8c363d61573fee0f 194 PRINTS PR00127 Clp protease catalytic subunit P signature 90 107 6.3E-55 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CO689_RS09300 e39c11c396606d2d8c363d61573fee0f 194 PRINTS PR00127 Clp protease catalytic subunit P signature 111 130 6.3E-55 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CO689_RS09300 e39c11c396606d2d8c363d61573fee0f 194 Pfam PF00574 Clp protease 13 192 3.3E-88 T 28-03-2018 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA CO689_RS09300 e39c11c396606d2d8c363d61573fee0f 194 SUPERFAMILY SSF52096 11 192 3.45E-74 T 28-03-2018 IPR029045 ClpP/crotonase-like domain CO689_RS09300 e39c11c396606d2d8c363d61573fee0f 194 Hamap MF_00444 ATP-dependent Clp protease proteolytic subunit [clpP]. 3 193 43.924 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CO689_RS09300 e39c11c396606d2d8c363d61573fee0f 194 ProSitePatterns PS00381 Endopeptidase Clp serine active site. 90 101 - T 28-03-2018 IPR018215 ClpP, Ser active site CO689_RS09300 e39c11c396606d2d8c363d61573fee0f 194 ProSitePatterns PS00382 Endopeptidase Clp histidine active site. 112 125 - T 28-03-2018 IPR033135 ClpP, histidine active site CO689_RS03330 7eb05fcf4719021e2ff65878eef422a1 254 PIRSF PIRSF004846 1 254 3.9E-80 T 28-03-2018 IPR005950 Molybdate ABC transporter, substrate-binding protein GO:0015689|GO:0030288 CO689_RS03330 7eb05fcf4719021e2ff65878eef422a1 254 Gene3D G3DSA:3.40.190.10 126 218 5.1E-27 T 28-03-2018 CO689_RS03330 7eb05fcf4719021e2ff65878eef422a1 254 Gene3D G3DSA:3.40.190.10 34 125 3.1E-16 T 28-03-2018 CO689_RS03330 7eb05fcf4719021e2ff65878eef422a1 254 TIGRFAM TIGR01256 modA: molybdate ABC transporter, periplasmic molybdate-binding protein 41 250 2.7E-57 T 28-03-2018 IPR005950 Molybdate ABC transporter, substrate-binding protein GO:0015689|GO:0030288 CO689_RS03330 7eb05fcf4719021e2ff65878eef422a1 254 Pfam PF13531 Bacterial extracellular solute-binding protein 36 252 4.5E-41 T 28-03-2018 CO689_RS03330 7eb05fcf4719021e2ff65878eef422a1 254 SUPERFAMILY SSF53850 35 253 1.48E-56 T 28-03-2018 CO689_RS04690 7299f5fbaad2d1b1d1178bf53ca572eb 1053 Gene3D G3DSA:3.30.420.10 5 238 2.6E-4 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CO689_RS04690 7299f5fbaad2d1b1d1178bf53ca572eb 1053 Hamap MF_01480 CRISPR-associated endonuclease Cas9 [cas9]. 3 1051 12.808 T 28-03-2018 IPR028629 CRISPR-associated endonuclease Cas9 GO:0004519 CO689_RS04690 7299f5fbaad2d1b1d1178bf53ca572eb 1053 TIGRFAM TIGR01865 cas_Csn1: CRISPR subtype II RNA-guided endonuclease Cas9 5 713 8.3E-139 T 28-03-2018 IPR028629 CRISPR-associated endonuclease Cas9 GO:0004519 CO689_RS04690 7299f5fbaad2d1b1d1178bf53ca572eb 1053 Gene3D G3DSA:3.40.1800.10 512 595 1.3E-4 T 28-03-2018 CO689_RS04690 7299f5fbaad2d1b1d1178bf53ca572eb 1053 Pfam PF13395 HNH endonuclease 534 589 7.2E-21 T 28-03-2018 IPR003615 HNH nuclease CO689_RS04690 7299f5fbaad2d1b1d1178bf53ca572eb 1053 Pfam PF16592 REC lobe of CRISPR-associated endonuclease Cas9 231 421 7.8E-17 T 28-03-2018 IPR032240 CRISPR-associated endonuclease Cas9, REC lobe CO689_RS11945 d2e26064f0f1207b30d0181208498cad 118 Pfam PF06133 Control of competence regulator ComK, YlbF/YmcA 7 111 2.4E-18 T 28-03-2018 IPR010368 Control of competence regulator ComK, YlbF/YmcA CO689_RS11945 d2e26064f0f1207b30d0181208498cad 118 PIRSF PIRSF021287 1 118 5.2E-37 T 28-03-2018 IPR016783 Biofilm formation YmcA CO689_RS11945 d2e26064f0f1207b30d0181208498cad 118 SUPERFAMILY SSF158622 1 113 2.49E-27 T 28-03-2018 IPR023378 YheA/YmcA-like domain CO689_RS11945 d2e26064f0f1207b30d0181208498cad 118 Gene3D G3DSA:1.20.1500.10 6 114 3.8E-23 T 28-03-2018 IPR023378 YheA/YmcA-like domain CO689_RS10305 3421f3fbfd3d937c25e03e78421590c1 244 SUPERFAMILY SSF53474 5 241 2.44E-34 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CO689_RS10305 3421f3fbfd3d937c25e03e78421590c1 244 Pfam PF00756 Putative esterase 16 236 3.6E-47 T 28-03-2018 IPR000801 Putative esterase Reactome: R-HSA-156590 CO689_RS10305 3421f3fbfd3d937c25e03e78421590c1 244 Gene3D G3DSA:3.40.50.1820 2 244 2.2E-18 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CO689_RS12380 b69d34b0d359906f63915b03c075c71a 261 SUPERFAMILY SSF52540 6 247 1.11E-45 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CO689_RS12380 b69d34b0d359906f63915b03c075c71a 261 SMART SM00382 31 224 6.8E-6 T 28-03-2018 IPR003593 AAA+ ATPase domain CO689_RS12380 b69d34b0d359906f63915b03c075c71a 261 Pfam PF00005 ABC transporter 23 175 4.1E-22 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CO689_RS12380 b69d34b0d359906f63915b03c075c71a 261 Gene3D G3DSA:3.40.50.300 1 261 1.3E-49 T 28-03-2018 CO689_RS12890 f5609c6f49e6cfa74850ca558773d234 299 Gene3D G3DSA:1.10.443.10 117 293 3.6E-50 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 CO689_RS12890 f5609c6f49e6cfa74850ca558773d234 299 Hamap MF_01807 Tyrosine recombinase XerD [xerD]. 5 299 59.588 T 28-03-2018 IPR011932 Tyrosine recombinase XerD GO:0006310|GO:0009009 CO689_RS12890 f5609c6f49e6cfa74850ca558773d234 299 SUPERFAMILY SSF56349 5 293 1.35E-62 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CO689_RS12890 f5609c6f49e6cfa74850ca558773d234 299 Pfam PF00589 Phage integrase family 114 285 2.1E-51 T 28-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 CO689_RS12890 f5609c6f49e6cfa74850ca558773d234 299 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 9 91 3.2E-22 T 28-03-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 CO689_RS12890 f5609c6f49e6cfa74850ca558773d234 299 Gene3D G3DSA:1.10.150.130 2 116 2.5E-22 T 28-03-2018 IPR023109 Integrase/recombinase, N-terminal CO689_RS12890 f5609c6f49e6cfa74850ca558773d234 299 TIGRFAM TIGR02225 recomb_XerD: tyrosine recombinase XerD 10 299 1.8E-117 T 28-03-2018 IPR011932 Tyrosine recombinase XerD GO:0006310|GO:0009009 CO689_RS12890 f5609c6f49e6cfa74850ca558773d234 299 Hamap MF_01808 Tyrosine recombinase XerC [xerC]. 7 299 57.058 T 28-03-2018 IPR023009 Tyrosine recombinase XerC/XerD CO689_RS09975 5b42f73b99acb05a40ed78e6884af1e4 382 SUPERFAMILY SSF51905 96 372 2.24E-15 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CO689_RS09975 5b42f73b99acb05a40ed78e6884af1e4 382 SUPERFAMILY SSF51905 5 65 2.24E-15 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CO689_RS09975 5b42f73b99acb05a40ed78e6884af1e4 382 Gene3D G3DSA:3.50.50.60 193 382 1.6E-11 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CO689_RS09975 5b42f73b99acb05a40ed78e6884af1e4 382 Pfam PF13434 L-lysine 6-monooxygenase (NADPH-requiring) 5 304 3.8E-11 T 28-03-2018 IPR025700 L-lysine 6-monooxygenase/L-ornithine 5-monooxygenase CO689_RS09975 5b42f73b99acb05a40ed78e6884af1e4 382 Gene3D G3DSA:3.50.50.60 4 192 6.7E-10 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CO689_RS05010 b553c85c6947814c70609676d227a1d9 440 Pfam PF13520 Amino acid permease 11 415 6.1E-61 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CO689_RS05010 b553c85c6947814c70609676d227a1d9 440 PIRSF PIRSF006060 1 440 1.1E-86 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CO689_RS07655 8fae9a88f644e957c7e3fff334693680 199 Pfam PF16883 Domain of unknown function (DUF5080) 4 198 2.6E-37 T 28-03-2018 IPR031689 Protein of unknown function DUF5080 CO689_RS00670 2fe4c1ba8303dd21455dc754e5069343 40 TIGRFAM TIGR01168 YSIRK_signal: gram-positive signal peptide, YSIRK family 13 40 5.4E-14 T 28-03-2018 IPR005877 YSIRK Gram-positive signal peptide GO:0016020 CO689_RS00670 2fe4c1ba8303dd21455dc754e5069343 40 Pfam PF04650 YSIRK type signal peptide 16 40 1.2E-14 T 28-03-2018 IPR005877 YSIRK Gram-positive signal peptide GO:0016020 CO689_RS11525 687283a5dbb86874acc3be6c0eb6de6f 308 Gene3D G3DSA:3.40.366.10 3 140 2.3E-35 T 28-03-2018 CO689_RS11525 687283a5dbb86874acc3be6c0eb6de6f 308 SUPERFAMILY SSF55048 127 195 3.27E-16 T 28-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 CO689_RS11525 687283a5dbb86874acc3be6c0eb6de6f 308 Gene3D G3DSA:3.40.366.10 186 308 9.2E-29 T 28-03-2018 CO689_RS11525 687283a5dbb86874acc3be6c0eb6de6f 308 TIGRFAM TIGR00128 fabD: malonyl CoA-acyl carrier protein transacylase 3 289 4.1E-99 T 28-03-2018 IPR004410 Malonyl CoA-acyl carrier protein transacylase, FabD-type GO:0004314 KEGG: 00061+2.3.1.39|MetaCyc: PWY-4381|MetaCyc: PWY-6799|MetaCyc: PWY-7388 CO689_RS11525 687283a5dbb86874acc3be6c0eb6de6f 308 Gene3D G3DSA:3.30.70.250 141 185 9.7E-21 T 28-03-2018 CO689_RS11525 687283a5dbb86874acc3be6c0eb6de6f 308 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 7 304 8.4E-36 T 28-03-2018 IPR020801 Polyketide synthase, acyl transferase domain CO689_RS11525 687283a5dbb86874acc3be6c0eb6de6f 308 PIRSF PIRSF000446 1 306 1.1E-101 T 28-03-2018 IPR024925 Malonyl CoA-acyl carrier protein transacylase KEGG: 00061+2.3.1.39|MetaCyc: PWY-4381|MetaCyc: PWY-6799|MetaCyc: PWY-7388 CO689_RS11525 687283a5dbb86874acc3be6c0eb6de6f 308 SUPERFAMILY SSF52151 4 119 3.92E-75 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CO689_RS11525 687283a5dbb86874acc3be6c0eb6de6f 308 SUPERFAMILY SSF52151 188 305 3.92E-75 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CO689_RS11525 687283a5dbb86874acc3be6c0eb6de6f 308 Pfam PF00698 Acyl transferase domain 7 284 2.7E-35 T 28-03-2018 IPR014043 Acyl transferase CO689_RS01670 5b3e3c7415228905e1a8752546d9e03e 270 Pfam PF00912 Transglycosylase 76 251 9.6E-53 T 28-03-2018 IPR001264 Glycosyl transferase, family 51 CO689_RS01670 5b3e3c7415228905e1a8752546d9e03e 270 Gene3D G3DSA:1.10.3810.10 64 269 6.4E-62 T 28-03-2018 IPR001264 Glycosyl transferase, family 51 CO689_RS01670 5b3e3c7415228905e1a8752546d9e03e 270 SUPERFAMILY SSF53955 77 266 7.31E-56 T 28-03-2018 IPR023346 Lysozyme-like domain CO689_RS11455 0af6a1cbccf6a6368c483f7b02f5bc06 364 Pfam PF13394 4Fe-4S single cluster domain 126 232 1.1E-6 T 28-03-2018 CO689_RS11455 0af6a1cbccf6a6368c483f7b02f5bc06 364 Pfam PF04055 Radical SAM superfamily 121 284 8.5E-19 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CO689_RS11455 0af6a1cbccf6a6368c483f7b02f5bc06 364 PIRSF PIRSF006004 9 364 4.0E-140 T 28-03-2018 IPR004383 Ribosomal RNA large subunit methyltransferase RlmN/Cfr GO:0005737|GO:0006364|GO:0008173 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CO689_RS11455 0af6a1cbccf6a6368c483f7b02f5bc06 364 SUPERFAMILY SSF102114 113 331 1.57E-14 T 28-03-2018 CO689_RS11455 0af6a1cbccf6a6368c483f7b02f5bc06 364 Gene3D G3DSA:3.20.20.70 28 360 2.2E-40 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CO689_RS11455 0af6a1cbccf6a6368c483f7b02f5bc06 364 Hamap MF_01849 Dual-specificity RNA methyltransferase RlmN [rlmN]. 18 360 73.715 T 28-03-2018 IPR027492 Dual-specificity RNA methyltransferase RlmN GO:0030488|GO:0070475 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CO689_RS11455 0af6a1cbccf6a6368c483f7b02f5bc06 364 TIGRFAM TIGR00048 rRNA_mod_RlmN: 23S rRNA (adenine(2503)-C(2))-methyltransferase 17 363 4.9E-156 T 28-03-2018 IPR027492 Dual-specificity RNA methyltransferase RlmN GO:0030488|GO:0070475 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CO689_RS03845 7bf04ee2c7883ae9f6d268dfdf62b976 452 ProSitePatterns PS00217 Sugar transport proteins signature 2. 106 131 - T 28-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CO689_RS03845 7bf04ee2c7883ae9f6d268dfdf62b976 452 PRINTS PR00171 Sugar transporter signature 340 361 1.1E-28 T 28-03-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 CO689_RS03845 7bf04ee2c7883ae9f6d268dfdf62b976 452 PRINTS PR00171 Sugar transporter signature 363 375 1.1E-28 T 28-03-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 CO689_RS03845 7bf04ee2c7883ae9f6d268dfdf62b976 452 PRINTS PR00171 Sugar transporter signature 252 262 1.1E-28 T 28-03-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 CO689_RS03845 7bf04ee2c7883ae9f6d268dfdf62b976 452 PRINTS PR00171 Sugar transporter signature 18 28 1.1E-28 T 28-03-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 CO689_RS03845 7bf04ee2c7883ae9f6d268dfdf62b976 452 PRINTS PR00171 Sugar transporter signature 101 120 1.1E-28 T 28-03-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 CO689_RS03845 7bf04ee2c7883ae9f6d268dfdf62b976 452 Pfam PF00083 Sugar (and other) transporter 12 438 2.3E-112 T 28-03-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 CO689_RS03845 7bf04ee2c7883ae9f6d268dfdf62b976 452 Gene3D G3DSA:1.20.1250.20 1 204 2.4E-39 T 28-03-2018 CO689_RS03845 7bf04ee2c7883ae9f6d268dfdf62b976 452 Gene3D G3DSA:1.20.1250.20 217 449 6.3E-40 T 28-03-2018 CO689_RS03845 7bf04ee2c7883ae9f6d268dfdf62b976 452 SUPERFAMILY SSF103473 6 436 1.44E-79 T 28-03-2018 IPR020846 Major facilitator superfamily domain CO689_RS03845 7bf04ee2c7883ae9f6d268dfdf62b976 452 TIGRFAM TIGR00879 SP: MFS transporter, sugar porter (SP) family 8 435 1.2E-108 T 28-03-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 CO689_RS03845 7bf04ee2c7883ae9f6d268dfdf62b976 452 ProSitePatterns PS00216 Sugar transport proteins signature 1. 64 81 - T 28-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CO689_RS03190 94c8e0415200d4bfc836e55a6bafd0e9 284 TIGRFAM TIGR00776 RhaT: RhaT L-rhamnose-proton symporter family protein 1 280 2.8E-101 T 28-03-2018 CO689_RS03190 94c8e0415200d4bfc836e55a6bafd0e9 284 SUPERFAMILY SSF103481 191 273 9.29E-8 T 28-03-2018 CO689_RS03190 94c8e0415200d4bfc836e55a6bafd0e9 284 Pfam PF06800 Sugar transport protein 4 280 7.7E-101 T 28-03-2018 IPR010651 Sugar transport protein GO:0015144|GO:0016021|GO:0034219 CO689_RS03190 94c8e0415200d4bfc836e55a6bafd0e9 284 SUPERFAMILY SSF103481 36 138 4.71E-7 T 28-03-2018 CO689_RS03265 c818bc46d57c08c8286deefcfbc477ec 285 Gene3D G3DSA:3.40.50.300 1 278 5.7E-56 T 28-03-2018 CO689_RS03265 c818bc46d57c08c8286deefcfbc477ec 285 Pfam PF00005 ABC transporter 18 149 1.1E-24 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CO689_RS03265 c818bc46d57c08c8286deefcfbc477ec 285 SUPERFAMILY SSF52540 2 211 1.38E-52 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CO689_RS03265 c818bc46d57c08c8286deefcfbc477ec 285 ProSitePatterns PS00211 ABC transporters family signature. 121 135 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CO689_RS03265 c818bc46d57c08c8286deefcfbc477ec 285 SMART SM00382 26 197 4.1E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain CO689_RS09615 67e481bd2efdf7c75da20d727976211c 148 Hamap MF_00984 Single-stranded DNA-binding protein. 2 107 35.437 T 28-03-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 CO689_RS09615 67e481bd2efdf7c75da20d727976211c 148 TIGRFAM TIGR00621 ssb: single-stranded DNA-binding protein 1 148 4.3E-43 T 28-03-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 CO689_RS09615 67e481bd2efdf7c75da20d727976211c 148 PIRSF PIRSF002070 1 148 7.6E-43 T 28-03-2018 CO689_RS09615 67e481bd2efdf7c75da20d727976211c 148 Pfam PF00436 Single-strand binding protein family 2 103 1.4E-36 T 28-03-2018 IPR000424 Primosome PriB/single-strand DNA-binding GO:0003697 Reactome: R-HSA-2151201 CO689_RS09615 67e481bd2efdf7c75da20d727976211c 148 Gene3D G3DSA:2.40.50.140 1 123 3.7E-41 T 28-03-2018 CO689_RS09615 67e481bd2efdf7c75da20d727976211c 148 SUPERFAMILY SSF50249 1 148 7.2E-51 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CO689_RS09260 fe1ed895bb689ca23247a9c694188021 410 Pfam PF05065 Phage capsid family 138 400 6.7E-34 T 28-03-2018 IPR024455 Phage capsid CO689_RS09260 fe1ed895bb689ca23247a9c694188021 410 TIGRFAM TIGR01554 major_cap_HK97: phage major capsid protein, HK97 family 18 400 3.8E-48 T 28-03-2018 IPR024455 Phage capsid CO689_RS09260 fe1ed895bb689ca23247a9c694188021 410 SUPERFAMILY SSF56563 131 401 1.57E-38 T 28-03-2018 CO689_RS09260 fe1ed895bb689ca23247a9c694188021 410 Gene3D G3DSA:3.30.2400.10 158 296 1.1E-17 T 28-03-2018 CO689_RS00535 54e37c3b763b21476ffd00c5e51f98fb 26 Pfam PF13333 Integrase core domain 3 24 9.0E-5 T 28-03-2018 IPR001584 Integrase, catalytic core GO:0015074 CO689_RS12060 6fb4c8a29325568da6f46706b3468352 177 SUPERFAMILY SSF50199 44 177 5.23E-37 T 28-03-2018 IPR016071 Staphylococcal nuclease (SNase-like), OB-fold CO689_RS12060 6fb4c8a29325568da6f46706b3468352 177 Pfam PF00565 Staphylococcal nuclease homologue 71 177 2.8E-33 T 28-03-2018 IPR016071 Staphylococcal nuclease (SNase-like), OB-fold CO689_RS12060 6fb4c8a29325568da6f46706b3468352 177 SMART SM00318 45 177 1.9E-38 T 28-03-2018 IPR016071 Staphylococcal nuclease (SNase-like), OB-fold CO689_RS12060 6fb4c8a29325568da6f46706b3468352 177 Gene3D G3DSA:2.40.50.90 39 177 1.2E-38 T 28-03-2018 IPR035437 Staphylococcal nuclease (SNase-like), OB-fold/extended TUDOR domain CO689_RS13000 b4c3925c8ef4beda4b0a06b248c510db 291 Gene3D G3DSA:1.10.600.10 1 291 3.9E-78 T 28-03-2018 IPR008949 Isoprenoid synthase domain CO689_RS13000 b4c3925c8ef4beda4b0a06b248c510db 291 Pfam PF00348 Polyprenyl synthetase 24 269 1.3E-58 T 28-03-2018 IPR000092 Polyprenyl synthetase GO:0008299 CO689_RS13000 b4c3925c8ef4beda4b0a06b248c510db 291 SUPERFAMILY SSF48576 2 273 1.48E-80 T 28-03-2018 IPR008949 Isoprenoid synthase domain CO689_RS13000 b4c3925c8ef4beda4b0a06b248c510db 291 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 76 92 - T 28-03-2018 IPR033749 Polyprenyl synthetase, conserved site CO689_RS13000 b4c3925c8ef4beda4b0a06b248c510db 291 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 207 219 - T 28-03-2018 IPR033749 Polyprenyl synthetase, conserved site CO689_RS00470 7d947b2b7309d55c597c237779f19669 33 ProDom PD610536 SE2200 SAV2627.1 SA2420.1 MW2548 1 33 5.0E-4 T 28-03-2018 IPR022561 Protein of unknown function DUF2648 CO689_RS00470 7d947b2b7309d55c597c237779f19669 33 Pfam PF10855 Protein of unknown function (DUF2648) 1 33 4.0E-11 T 28-03-2018 IPR022561 Protein of unknown function DUF2648 CO689_RS06555 46a397c0f5b3ccd7f584e2c7f7c95729 173 Pfam PF05656 Protein of unknown function (DUF805) 20 154 3.0E-17 T 28-03-2018 IPR008523 Protein of unknown function DUF805 GO:0016021 CO689_RS06455 8dccf501ecbba9b831a55400e6506640 146 Gene3D G3DSA:1.10.10.10 1 138 1.1E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS06455 8dccf501ecbba9b831a55400e6506640 146 PRINTS PR00598 Bacterial regulatory protein MarR family signature 56 72 1.2E-5 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CO689_RS06455 8dccf501ecbba9b831a55400e6506640 146 PRINTS PR00598 Bacterial regulatory protein MarR family signature 73 88 1.2E-5 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CO689_RS06455 8dccf501ecbba9b831a55400e6506640 146 PRINTS PR00598 Bacterial regulatory protein MarR family signature 92 108 1.2E-5 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CO689_RS06455 8dccf501ecbba9b831a55400e6506640 146 Pfam PF01047 MarR family 39 96 6.0E-12 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CO689_RS06455 8dccf501ecbba9b831a55400e6506640 146 SMART SM00347 32 132 1.2E-14 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CO689_RS06455 8dccf501ecbba9b831a55400e6506640 146 SUPERFAMILY SSF46785 29 144 2.7E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS09685 249d6076dde789e8242d369cfe9db7c8 140 SUPERFAMILY SSF51283 4 136 2.22E-34 T 28-03-2018 IPR029054 dUTPase-like CO689_RS09685 249d6076dde789e8242d369cfe9db7c8 140 TIGRFAM TIGR00576 dut: dUTP diphosphatase 4 140 7.7E-37 T 28-03-2018 IPR008181 Deoxyuridine triphosphate nucleotidohydrolase GO:0004170|GO:0046080 KEGG: 00240+3.6.1.23|Reactome: R-HSA-499943 CO689_RS09685 249d6076dde789e8242d369cfe9db7c8 140 Gene3D G3DSA:2.70.40.10 1 102 7.7E-40 T 28-03-2018 CO689_RS09685 249d6076dde789e8242d369cfe9db7c8 140 Pfam PF00692 dUTPase 12 137 1.4E-27 T 28-03-2018 IPR029054 dUTPase-like CO689_RS09685 249d6076dde789e8242d369cfe9db7c8 140 Gene3D G3DSA:2.70.40.10 103 139 1.2E-11 T 28-03-2018 CO689_RS04720 dcd2a658a191e9f5b398cf8cf3a4eede 473 Gene3D G3DSA:3.20.20.140 2 87 1.9E-25 T 28-03-2018 CO689_RS04720 dcd2a658a191e9f5b398cf8cf3a4eede 473 Pfam PF02614 Glucuronate isomerase 2 464 5.1E-203 T 28-03-2018 IPR003766 Uronate isomerase GO:0006064|GO:0008880 KEGG: 00040+5.3.1.12|MetaCyc: PWY-7247|MetaCyc: PWY-7248 CO689_RS04720 dcd2a658a191e9f5b398cf8cf3a4eede 473 Gene3D G3DSA:3.20.20.140 88 466 1.8E-136 T 28-03-2018 CO689_RS04720 dcd2a658a191e9f5b398cf8cf3a4eede 473 Hamap MF_00675 Uronate isomerase [uxaC]. 1 466 47.224 T 28-03-2018 IPR003766 Uronate isomerase GO:0006064|GO:0008880 KEGG: 00040+5.3.1.12|MetaCyc: PWY-7247|MetaCyc: PWY-7248 CO689_RS04720 dcd2a658a191e9f5b398cf8cf3a4eede 473 SUPERFAMILY SSF51556 1 465 1.06E-167 T 28-03-2018 IPR032466 Metal-dependent hydrolase CO689_RS05165 384f6966500508c933204f024b70c49c 210 Gene3D G3DSA:3.40.50.300 1 204 1.4E-17 T 28-03-2018 CO689_RS05165 384f6966500508c933204f024b70c49c 210 SUPERFAMILY SSF52540 2 204 7.79E-18 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CO689_RS05165 384f6966500508c933204f024b70c49c 210 Pfam PF00005 ABC transporter 17 142 3.3E-6 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CO689_RS03385 63909948322a3b4d464bbf107b945618 309 PIRSF PIRSF016502 1 307 2.8E-77 T 28-03-2018 IPR004937 Urea transporter GO:0015204|GO:0016021|GO:0071918 Reactome: R-HSA-425366 CO689_RS03385 63909948322a3b4d464bbf107b945618 309 Gene3D G3DSA:1.10.3430.10 1 308 7.3E-80 T 28-03-2018 CO689_RS03385 63909948322a3b4d464bbf107b945618 309 TIGRFAM TIGR03441 urea_trans_yut: urea transporter 3 293 6.5E-104 T 28-03-2018 IPR017807 Urea transporter, bacteria GO:0015204|GO:0016021|GO:0071918 CO689_RS03385 63909948322a3b4d464bbf107b945618 309 Pfam PF03253 Urea transporter 5 294 2.3E-78 T 28-03-2018 IPR004937 Urea transporter GO:0015204|GO:0016021|GO:0071918 Reactome: R-HSA-425366 CO689_RS10960 3b2e86eaaba18395e03e43fc64ff2162 406 Pfam PF01098 Cell cycle protein 23 386 1.3E-91 T 28-03-2018 IPR001182 Probable peptidoglycan glycosyltransferase FtsW/RodA GO:0016021|GO:0051301 CO689_RS08505 9beb86dcd716f702ec8d1b2a5d608df3 429 SUPERFAMILY SSF56601 1 314 1.11E-69 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CO689_RS08505 9beb86dcd716f702ec8d1b2a5d608df3 429 Gene3D G3DSA:2.30.140.20 314 380 3.1E-25 T 28-03-2018 IPR015294 Penicillin-binding protein 4, C-terminal domain CO689_RS08505 9beb86dcd716f702ec8d1b2a5d608df3 429 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 73 84 1.6E-14 T 28-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 CO689_RS08505 9beb86dcd716f702ec8d1b2a5d608df3 429 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 157 170 1.6E-14 T 28-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 CO689_RS08505 9beb86dcd716f702ec8d1b2a5d608df3 429 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 130 147 1.6E-14 T 28-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 CO689_RS08505 9beb86dcd716f702ec8d1b2a5d608df3 429 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 55 287 1.1E-52 T 28-03-2018 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 CO689_RS08505 9beb86dcd716f702ec8d1b2a5d608df3 429 Gene3D G3DSA:3.40.710.10 35 313 1.5E-37 T 28-03-2018 CO689_RS08505 9beb86dcd716f702ec8d1b2a5d608df3 429 Pfam PF09211 Domain of unknown function (DUF1958) 316 381 5.7E-25 T 28-03-2018 IPR015294 Penicillin-binding protein 4, C-terminal domain CO689_RS08505 9beb86dcd716f702ec8d1b2a5d608df3 429 SUPERFAMILY SSF69189 315 381 2.39E-21 T 28-03-2018 IPR015956 Penicillin-binding protein-associated GO:0004180|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 CO689_RS06170 a1a91bc2840e2e8be9579b518a54d84f 518 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 201 217 1.7E-23 T 28-03-2018 CO689_RS06170 a1a91bc2840e2e8be9579b518a54d84f 518 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 331 355 1.7E-23 T 28-03-2018 CO689_RS06170 a1a91bc2840e2e8be9579b518a54d84f 518 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 227 241 1.7E-23 T 28-03-2018 CO689_RS06170 a1a91bc2840e2e8be9579b518a54d84f 518 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 295 307 1.7E-23 T 28-03-2018 CO689_RS06170 a1a91bc2840e2e8be9579b518a54d84f 518 Pfam PF12161 HsdM N-terminal domain 14 166 2.0E-21 T 28-03-2018 IPR022749 N6 adenine-specific DNA methyltransferase, N-terminal domain CO689_RS06170 a1a91bc2840e2e8be9579b518a54d84f 518 Gene3D G3DSA:3.40.50.150 199 474 1.5E-74 T 28-03-2018 CO689_RS06170 a1a91bc2840e2e8be9579b518a54d84f 518 Pfam PF02384 N-6 DNA Methylase 178 480 4.5E-115 T 28-03-2018 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 CO689_RS06170 a1a91bc2840e2e8be9579b518a54d84f 518 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 298 304 - T 28-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 CO689_RS06170 a1a91bc2840e2e8be9579b518a54d84f 518 TIGRFAM TIGR00497 hsdM: type I restriction-modification system, M subunit 10 496 2.9E-145 T 28-03-2018 IPR004546 Restriction endonuclease, type I, HsdM GO:0003677|GO:0009007|GO:0009307 CO689_RS06170 a1a91bc2840e2e8be9579b518a54d84f 518 SUPERFAMILY SSF53335 86 514 1.12E-138 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CO689_RS06170 a1a91bc2840e2e8be9579b518a54d84f 518 SUPERFAMILY SSF53335 13 51 1.12E-138 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CO689_RS02265 ee05529179eec4b4545dd2027e90e1e1 108 TIGRFAM TIGR00377 ant_ant_sig: anti-anti-sigma factor 1 106 4.3E-33 T 28-03-2018 IPR003658 Anti-sigma factor antagonist GO:0006355|GO:0045152 CO689_RS02265 ee05529179eec4b4545dd2027e90e1e1 108 Pfam PF01740 STAS domain 5 99 4.6E-15 T 28-03-2018 IPR002645 STAS domain CO689_RS02265 ee05529179eec4b4545dd2027e90e1e1 108 SUPERFAMILY SSF52091 3 101 5.49E-25 T 28-03-2018 IPR002645 STAS domain CO689_RS02265 ee05529179eec4b4545dd2027e90e1e1 108 Gene3D G3DSA:3.30.750.24 1 104 9.0E-18 T 28-03-2018 IPR002645 STAS domain CO689_RS12420 903a18e1461dd1637606ac4aadc80344 310 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 106 298 6.2E-22 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CO689_RS12420 903a18e1461dd1637606ac4aadc80344 310 TIGRFAM TIGR00974 3a0107s02c: phosphate ABC transporter, permease protein PstA 34 307 7.4E-87 T 28-03-2018 IPR005672 Phosphate transport system permease protein PstA GO:0005315|GO:0005887|GO:0035435 CO689_RS12420 903a18e1461dd1637606ac4aadc80344 310 Gene3D G3DSA:1.10.3720.10 35 310 7.3E-42 T 28-03-2018 CO689_RS12420 903a18e1461dd1637606ac4aadc80344 310 SUPERFAMILY SSF161098 34 302 1.28E-35 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CO689_RS11930 0744f06387833370305bd3cb3ffeb671 322 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 116 320 2.6E-43 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CO689_RS11930 0744f06387833370305bd3cb3ffeb671 322 Gene3D G3DSA:1.10.3720.10 3 309 6.7E-44 T 28-03-2018 CO689_RS11930 0744f06387833370305bd3cb3ffeb671 322 SUPERFAMILY SSF161098 94 304 1.83E-18 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CO689_RS06620 da724cc875289fc30b176abcf7e7f0ab 315 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 19 295 6.0E-89 T 28-03-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 CO689_RS06620 da724cc875289fc30b176abcf7e7f0ab 315 SUPERFAMILY SSF160240 220 294 1.96E-11 T 28-03-2018 CO689_RS06620 da724cc875289fc30b176abcf7e7f0ab 315 Gene3D G3DSA:3.30.70.1350 214 296 3.6E-14 T 28-03-2018 IPR027470 Cation efflux protein, cytoplasmic domain CO689_RS06620 da724cc875289fc30b176abcf7e7f0ab 315 SUPERFAMILY SSF161111 17 216 2.09E-57 T 28-03-2018 CO689_RS06620 da724cc875289fc30b176abcf7e7f0ab 315 Gene3D G3DSA:1.20.1510.10 17 213 5.6E-59 T 28-03-2018 CO689_RS06620 da724cc875289fc30b176abcf7e7f0ab 315 Pfam PF01545 Cation efflux family 22 215 4.2E-49 T 28-03-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 CO689_RS10945 f64373c05c23404ef77ef3db58fc171d 67 Pfam PF09963 Uncharacterized protein conserved in bacteria (DUF2197) 3 50 4.3E-17 T 28-03-2018 IPR019241 Protein of unknown function DUF2197 CO689_RS10945 f64373c05c23404ef77ef3db58fc171d 67 Gene3D G3DSA:2.10.110.10 5 66 6.0E-4 T 28-03-2018 CO689_RS02545 1af388ea9a4429de0270100523804f49 116 SUPERFAMILY SSF46785 4 103 9.09E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS02545 1af388ea9a4429de0270100523804f49 116 Gene3D G3DSA:1.10.10.10 1 111 4.4E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS02545 1af388ea9a4429de0270100523804f49 116 Pfam PF01638 HxlR-like helix-turn-helix 13 104 2.2E-16 T 28-03-2018 IPR002577 Helix-turn-helix, HxlR type CO689_RS02575 1764d3dbe2acd781ec9ddbd28a7184e2 286 Pfam PF00583 Acetyltransferase (GNAT) family 44 144 6.9E-13 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CO689_RS02575 1764d3dbe2acd781ec9ddbd28a7184e2 286 SUPERFAMILY SSF55729 183 241 5.32E-6 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CO689_RS02575 1764d3dbe2acd781ec9ddbd28a7184e2 286 Gene3D G3DSA:3.40.630.30 4 181 3.9E-17 T 28-03-2018 CO689_RS02575 1764d3dbe2acd781ec9ddbd28a7184e2 286 SUPERFAMILY SSF55729 9 152 7.5E-20 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CO689_RS02575 1764d3dbe2acd781ec9ddbd28a7184e2 286 Gene3D G3DSA:3.40.630.30 182 280 3.0E-6 T 28-03-2018 CO689_RS10390 1ef7a4038c2e14b140168b4845364a7a 204 Pfam PF01634 ATP phosphoribosyltransferase 53 198 6.9E-45 T 28-03-2018 IPR013820 ATP phosphoribosyltransferase, catalytic domain GO:0000105|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 CO689_RS10390 1ef7a4038c2e14b140168b4845364a7a 204 SUPERFAMILY SSF53850 1 198 1.63E-54 T 28-03-2018 CO689_RS10390 1ef7a4038c2e14b140168b4845364a7a 204 Gene3D G3DSA:3.40.190.10 1 109 1.2E-28 T 28-03-2018 CO689_RS10390 1ef7a4038c2e14b140168b4845364a7a 204 Hamap MF_01018 ATP phosphoribosyltransferase [hisG]. 1 203 45.796 T 28-03-2018 IPR024893 ATP phosphoribosyltransferase HisG, short form GO:0000105|GO:0003879 KEGG: 00340+2.4.2.17 CO689_RS10390 1ef7a4038c2e14b140168b4845364a7a 204 Gene3D G3DSA:3.40.190.10 110 170 4.7E-22 T 28-03-2018 CO689_RS10390 1ef7a4038c2e14b140168b4845364a7a 204 TIGRFAM TIGR00070 hisG: ATP phosphoribosyltransferase 2 178 4.4E-54 T 28-03-2018 IPR013820 ATP phosphoribosyltransferase, catalytic domain GO:0000105|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 CO689_RS11405 701555053511c80e12ad610701ca6cfc 105 SUPERFAMILY SSF52833 2 100 2.56E-13 T 28-03-2018 IPR012336 Thioredoxin-like fold CO689_RS11405 701555053511c80e12ad610701ca6cfc 105 Gene3D G3DSA:3.40.30.10 1 105 4.6E-10 T 28-03-2018 CO689_RS11405 701555053511c80e12ad610701ca6cfc 105 Pfam PF00085 Thioredoxin 12 99 5.7E-6 T 28-03-2018 IPR013766 Thioredoxin domain GO:0045454 CO689_RS02695 e4ac5b7532ef03d7364169f924273e3b 285 Gene3D G3DSA:3.40.50.1000 1 285 3.5E-34 T 28-03-2018 IPR023214 HAD-like domain CO689_RS02695 e4ac5b7532ef03d7364169f924273e3b 285 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 7 278 4.2E-51 T 28-03-2018 IPR000150 Cof family GO:0016787 CO689_RS02695 e4ac5b7532ef03d7364169f924273e3b 285 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 6 98 3.9E-14 T 28-03-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 CO689_RS02695 e4ac5b7532ef03d7364169f924273e3b 285 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 181 250 2.2E-11 T 28-03-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 CO689_RS02695 e4ac5b7532ef03d7364169f924273e3b 285 Pfam PF08282 haloacid dehalogenase-like hydrolase 7 278 1.1E-54 T 28-03-2018 IPR023214 HAD-like domain CO689_RS02695 e4ac5b7532ef03d7364169f924273e3b 285 SUPERFAMILY SSF56784 2 283 9.32E-58 T 28-03-2018 IPR023214 HAD-like domain CO689_RS07945 e70f23f981346e813f22f8aa939c16fe 168 Gene3D G3DSA:4.10.860.10 94 166 5.8E-9 T 28-03-2018 IPR001943 UVR domain GO:0005515 CO689_RS07945 e70f23f981346e813f22f8aa939c16fe 168 Pfam PF02151 UvrB/uvrC motif 130 165 7.1E-6 T 28-03-2018 IPR001943 UVR domain GO:0005515 CO689_RS07945 e70f23f981346e813f22f8aa939c16fe 168 SUPERFAMILY SSF46600 129 165 4.05E-5 T 28-03-2018 IPR001943 UVR domain GO:0005515 CO689_RS08440 39199b921a30e1c6c0a0e475e3a0d2f1 163 SUPERFAMILY SSF55729 1 161 6.1E-29 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CO689_RS08440 39199b921a30e1c6c0a0e475e3a0d2f1 163 Gene3D G3DSA:3.40.630.30 1 163 9.9E-26 T 28-03-2018 CO689_RS08440 39199b921a30e1c6c0a0e475e3a0d2f1 163 Pfam PF13420 Acetyltransferase (GNAT) domain 4 153 2.9E-14 T 28-03-2018 CO689_RS11775 a438a4b0ec6fc29027c490c2f9967c40 225 SMART SM00448 2 113 1.3E-42 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CO689_RS11775 a438a4b0ec6fc29027c490c2f9967c40 225 SMART SM00862 149 223 8.8E-23 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CO689_RS11775 a438a4b0ec6fc29027c490c2f9967c40 225 Pfam PF00486 Transcriptional regulatory protein, C terminal 152 223 4.9E-24 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CO689_RS11775 a438a4b0ec6fc29027c490c2f9967c40 225 SUPERFAMILY SSF52172 3 179 8.2E-42 T 28-03-2018 IPR011006 CheY-like superfamily CO689_RS11775 a438a4b0ec6fc29027c490c2f9967c40 225 Gene3D G3DSA:1.10.10.10 125 225 8.8E-30 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS11775 a438a4b0ec6fc29027c490c2f9967c40 225 Gene3D G3DSA:3.40.50.2300 2 124 7.6E-37 T 28-03-2018 CO689_RS11775 a438a4b0ec6fc29027c490c2f9967c40 225 Pfam PF00072 Response regulator receiver domain 4 114 1.5E-30 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CO689_RS09475 a3af36e98b6986e6d70b8c098523dfca 231 Gene3D G3DSA:1.10.3720.10 16 231 1.2E-42 T 28-03-2018 CO689_RS09475 a3af36e98b6986e6d70b8c098523dfca 231 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 64 231 4.1E-22 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CO689_RS09475 a3af36e98b6986e6d70b8c098523dfca 231 SUPERFAMILY SSF161098 20 218 5.36E-47 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CO689_RS02400 c4592d9a2f46b20e9b3f717c6dddb62d 253 SUPERFAMILY SSF54106 54 95 1.83E-9 T 28-03-2018 IPR018392 LysM domain CO689_RS02400 c4592d9a2f46b20e9b3f717c6dddb62d 253 Gene3D G3DSA:1.10.530.10 166 253 1.3E-13 T 28-03-2018 CO689_RS02400 c4592d9a2f46b20e9b3f717c6dddb62d 253 Pfam PF01464 Transglycosylase SLT domain 184 231 1.0E-5 T 28-03-2018 IPR008258 Transglycosylase SLT domain 1 CO689_RS02400 c4592d9a2f46b20e9b3f717c6dddb62d 253 SUPERFAMILY SSF53955 191 252 1.75E-9 T 28-03-2018 IPR023346 Lysozyme-like domain CO689_RS02400 c4592d9a2f46b20e9b3f717c6dddb62d 253 Gene3D G3DSA:3.10.350.10 48 111 4.1E-15 T 28-03-2018 CO689_RS02400 c4592d9a2f46b20e9b3f717c6dddb62d 253 SMART SM00257 53 96 2.9E-13 T 28-03-2018 IPR018392 LysM domain CO689_RS02400 c4592d9a2f46b20e9b3f717c6dddb62d 253 Pfam PF01476 LysM domain 54 95 8.7E-10 T 28-03-2018 IPR018392 LysM domain CO689_RS01735 3e377cc5cb46343d634f32a402820964 233 PIRSF PIRSF031509 5 233 5.5E-55 T 28-03-2018 IPR016975 Cell wall-active antibiotic response protein GO:0016021 CO689_RS01735 3e377cc5cb46343d634f32a402820964 233 Pfam PF09922 Cell wall-active antibiotics response 4TMS YvqF 119 230 1.9E-32 T 28-03-2018 IPR024425 Cell wall-active antibiotics response 4TMS YvqF CO689_RS06080 03a47cb478c0f23e96e998e618357bf4 125 Gene3D G3DSA:3.40.50.510 1 122 1.4E-28 T 28-03-2018 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 CO689_RS06080 03a47cb478c0f23e96e998e618357bf4 125 Pfam PF03610 PTS system fructose IIA component 4 98 6.0E-20 T 28-03-2018 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 CO689_RS06080 03a47cb478c0f23e96e998e618357bf4 125 SUPERFAMILY SSF53062 1 118 2.35E-30 T 28-03-2018 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 CO689_RS11285 8cffa6f20c99b0c850816ff517ba4ee8 264 Gene3D G3DSA:3.10.180.10 64 226 1.1E-21 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CO689_RS11285 8cffa6f20c99b0c850816ff517ba4ee8 264 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 12 122 7.3E-11 T 28-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CO689_RS11285 8cffa6f20c99b0c850816ff517ba4ee8 264 SUPERFAMILY SSF54593 10 165 1.23E-31 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CO689_RS11285 8cffa6f20c99b0c850816ff517ba4ee8 264 Gene3D G3DSA:3.10.180.10 4 63 6.0E-5 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CO689_RS11285 8cffa6f20c99b0c850816ff517ba4ee8 264 SUPERFAMILY SSF54593 169 259 4.28E-6 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CO689_RS08420 aae6ec6e99516e92547633437ed61cc8 278 SUPERFAMILY SSF81345 4 260 2.88E-44 T 28-03-2018 IPR029022 ABC transporter, BtuC-like CO689_RS08420 aae6ec6e99516e92547633437ed61cc8 278 Gene3D G3DSA:1.10.3470.10 3 271 2.8E-33 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CO689_RS08420 aae6ec6e99516e92547633437ed61cc8 278 Pfam PF00950 ABC 3 transport family 10 265 9.9E-77 T 28-03-2018 IPR001626 ABC transporter, TroCD-like GO:0005887|GO:0042626|GO:0043190|GO:0055085 CO689_RS00070 a2429879787920958b9a16fb2e14c53f 80 Gene3D G3DSA:1.10.1220.10 48 80 1.0E-5 T 28-03-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 CO689_RS00070 a2429879787920958b9a16fb2e14c53f 80 SUPERFAMILY SSF47598 43 79 5.5E-5 T 28-03-2018 IPR010985 Ribbon-helix-helix GO:0006355 CO689_RS08335 94e36e6c2aed7d3029a3f6e750d54163 394 SUPERFAMILY SSF55031 187 298 6.41E-26 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain CO689_RS08335 94e36e6c2aed7d3029a3f6e750d54163 394 PIRSF PIRSF005962 1 394 9.7E-119 T 28-03-2018 IPR017439 Amidohydrolase GO:0016787 CO689_RS08335 94e36e6c2aed7d3029a3f6e750d54163 394 Pfam PF01546 Peptidase family M20/M25/M40 74 386 4.1E-29 T 28-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CO689_RS08335 94e36e6c2aed7d3029a3f6e750d54163 394 Gene3D G3DSA:3.40.630.10 269 394 3.3E-18 T 28-03-2018 CO689_RS08335 94e36e6c2aed7d3029a3f6e750d54163 394 Pfam PF07687 Peptidase dimerisation domain 187 279 2.0E-7 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain CO689_RS08335 94e36e6c2aed7d3029a3f6e750d54163 394 Gene3D G3DSA:3.40.630.10 1 268 4.9E-59 T 28-03-2018 CO689_RS08335 94e36e6c2aed7d3029a3f6e750d54163 394 SUPERFAMILY SSF53187 300 393 2.2E-82 T 28-03-2018 CO689_RS08335 94e36e6c2aed7d3029a3f6e750d54163 394 SUPERFAMILY SSF53187 4 199 2.2E-82 T 28-03-2018 CO689_RS08335 94e36e6c2aed7d3029a3f6e750d54163 394 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 16 378 1.3E-106 T 28-03-2018 IPR017439 Amidohydrolase GO:0016787 CO689_RS01170 067b6fd920e7227a8b5c7d9108476015 123 Hamap MF_00454 Putative fluoride ion transporter CrcB [crcB]. 3 118 17.437 T 28-03-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 CO689_RS01170 067b6fd920e7227a8b5c7d9108476015 123 Pfam PF02537 CrcB-like protein, Camphor Resistance (CrcB) 4 113 8.4E-26 T 28-03-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 CO689_RS11905 516a14966c62591fca68e77ad78e2d6f 96 SUPERFAMILY SSF89957 3 95 1.7E-19 T 28-03-2018 IPR029756 MTH1187/YkoF-like CO689_RS11905 516a14966c62591fca68e77ad78e2d6f 96 Gene3D G3DSA:3.30.70.930 1 96 6.8E-18 T 28-03-2018 IPR029756 MTH1187/YkoF-like CO689_RS11905 516a14966c62591fca68e77ad78e2d6f 96 Pfam PF01910 Thiamine-binding protein 6 95 2.8E-16 T 28-03-2018 IPR002767 Thiamine-binding protein CO689_RS10225 9e151a2cd6fca3ae7d51ce61ec72a7c4 602 Pfam PF08439 Oligopeptidase F 117 186 3.3E-22 T 28-03-2018 IPR013647 Oligopeptidase F, N-terminal domain CO689_RS10225 9e151a2cd6fca3ae7d51ce61ec72a7c4 602 Pfam PF01432 Peptidase family M3 207 587 3.7E-76 T 28-03-2018 IPR001567 Peptidase M3A/M3B catalytic domain GO:0004222|GO:0006508 CO689_RS10225 9e151a2cd6fca3ae7d51ce61ec72a7c4 602 Gene3D G3DSA:1.10.1370.10 102 600 1.8E-44 T 28-03-2018 CO689_RS10225 9e151a2cd6fca3ae7d51ce61ec72a7c4 602 SUPERFAMILY SSF55486 10 583 2.11E-122 T 28-03-2018 CO689_RS10225 9e151a2cd6fca3ae7d51ce61ec72a7c4 602 TIGRFAM TIGR00181 pepF: oligoendopeptidase F 15 599 2.2E-205 T 28-03-2018 IPR004438 Peptidase M3B, oligoendopeptidase F GO:0004222|GO:0006508 CO689_RS03620 dbdc13c712997dae2d06f590db52c58e 371 PIRSF PIRSF005962 1 371 4.0E-118 T 28-03-2018 IPR017439 Amidohydrolase GO:0016787 CO689_RS03620 dbdc13c712997dae2d06f590db52c58e 371 SUPERFAMILY SSF53187 3 187 2.04E-74 T 28-03-2018 CO689_RS03620 dbdc13c712997dae2d06f590db52c58e 371 SUPERFAMILY SSF53187 288 370 2.04E-74 T 28-03-2018 CO689_RS03620 dbdc13c712997dae2d06f590db52c58e 371 Pfam PF01546 Peptidase family M20/M25/M40 63 368 1.9E-32 T 28-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CO689_RS03620 dbdc13c712997dae2d06f590db52c58e 371 Gene3D G3DSA:3.40.630.10 1 226 2.4E-42 T 28-03-2018 CO689_RS03620 dbdc13c712997dae2d06f590db52c58e 371 Gene3D G3DSA:3.40.630.10 237 371 1.4E-16 T 28-03-2018 CO689_RS03620 dbdc13c712997dae2d06f590db52c58e 371 Pfam PF07687 Peptidase dimerisation domain 176 269 4.3E-8 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain CO689_RS03620 dbdc13c712997dae2d06f590db52c58e 371 SUPERFAMILY SSF55031 174 281 6.93E-29 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain CO689_RS03620 dbdc13c712997dae2d06f590db52c58e 371 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 7 359 5.8E-115 T 28-03-2018 IPR017439 Amidohydrolase GO:0016787 CO689_RS09250 2dc2d594ba82fc7b6d83e5a51cba8e27 377 Pfam PF04860 Phage portal protein 22 339 5.2E-63 T 28-03-2018 IPR006944 Bacteriophage/Gene transfer agent portal protein CO689_RS09250 2dc2d594ba82fc7b6d83e5a51cba8e27 377 TIGRFAM TIGR01537 portal_HK97: phage portal protein, HK97 family 16 345 5.7E-40 T 28-03-2018 IPR006427 Phage portal protein, HK97 CO689_RS13245 3afbcd65b285f805c249bfa152f4f380 114 ProSitePatterns PS01069 Prokaryotic diacylglycerol kinase signature. 59 70 - T 28-03-2018 IPR000829 DAGK family GO:0004143|GO:0008654|GO:0016020 KEGG: 00500+2.7.1.10|KEGG: 00561+2.7.1.107|KEGG: 00564+2.7.1.107|KEGG: 04070+2.7.1.107|MetaCyc: PWY-7039|MetaCyc: PWY-7817 CO689_RS13245 3afbcd65b285f805c249bfa152f4f380 114 Pfam PF01219 Prokaryotic diacylglycerol kinase 5 106 4.7E-32 T 28-03-2018 IPR000829 DAGK family GO:0004143|GO:0008654|GO:0016020 KEGG: 00500+2.7.1.10|KEGG: 00561+2.7.1.107|KEGG: 00564+2.7.1.107|KEGG: 04070+2.7.1.107|MetaCyc: PWY-7039|MetaCyc: PWY-7817 CO689_RS13245 3afbcd65b285f805c249bfa152f4f380 114 Gene3D G3DSA:1.10.3830.10 1 108 8.2E-36 T 28-03-2018 IPR000829 DAGK family GO:0004143|GO:0008654|GO:0016020 KEGG: 00500+2.7.1.10|KEGG: 00561+2.7.1.107|KEGG: 00564+2.7.1.107|KEGG: 04070+2.7.1.107|MetaCyc: PWY-7039|MetaCyc: PWY-7817 CO689_RS05975 ca44f3d77a2e9215943fba84796ffa53 317 Pfam PF12368 Rhodanase C-terminal 220 285 2.5E-15 T 28-03-2018 IPR022111 Rhodanase, C-terminal CO689_RS05975 ca44f3d77a2e9215943fba84796ffa53 317 Gene3D G3DSA:3.40.250.10 107 241 2.4E-26 T 28-03-2018 IPR001763 Rhodanese-like domain CO689_RS05975 ca44f3d77a2e9215943fba84796ffa53 317 Hamap MF_00469 UPF0176 protein YceA [yceA]. 1 265 39.924 T 28-03-2018 IPR020936 Uncharacterised protein family UPF0176 CO689_RS05975 ca44f3d77a2e9215943fba84796ffa53 317 SMART SM00450 113 214 3.6E-19 T 28-03-2018 IPR001763 Rhodanese-like domain CO689_RS05975 ca44f3d77a2e9215943fba84796ffa53 317 SUPERFAMILY SSF52821 86 246 1.37E-34 T 28-03-2018 IPR001763 Rhodanese-like domain CO689_RS05975 ca44f3d77a2e9215943fba84796ffa53 317 Pfam PF00581 Rhodanese-like domain 114 208 1.6E-11 T 28-03-2018 IPR001763 Rhodanese-like domain CO689_RS07400 6ac31ef6e224af4297f3acd12ee5c378 443 ProSitePatterns PS00610 Sodium:neurotransmitter symporter family signature 1. 28 42 - T 28-03-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 CO689_RS07400 6ac31ef6e224af4297f3acd12ee5c378 443 SUPERFAMILY SSF161070 5 442 3.27E-111 T 28-03-2018 CO689_RS07400 6ac31ef6e224af4297f3acd12ee5c378 443 Pfam PF00209 Sodium:neurotransmitter symporter family 5 116 9.4E-20 T 28-03-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 CO689_RS07400 6ac31ef6e224af4297f3acd12ee5c378 443 Pfam PF00209 Sodium:neurotransmitter symporter family 151 441 7.8E-27 T 28-03-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 CO689_RS07400 6ac31ef6e224af4297f3acd12ee5c378 443 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 87 113 2.3E-14 T 28-03-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 CO689_RS07400 6ac31ef6e224af4297f3acd12ee5c378 443 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 41 60 2.3E-14 T 28-03-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 CO689_RS07400 6ac31ef6e224af4297f3acd12ee5c378 443 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 12 33 2.3E-14 T 28-03-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 CO689_RS05320 a6c3a814488fea886fcb60c6b0043bb1 485 Pfam PF14296 O-antigen polysaccharide polymerase Wzy 9 470 1.7E-100 T 28-03-2018 IPR029468 O-antigen polysaccharide polymerase Wzy CO689_RS05320 a6c3a814488fea886fcb60c6b0043bb1 485 TIGRFAM TIGR04370 glyco_rpt_poly: oligosaccharide repeat unit polymerase 53 449 1.5E-26 T 28-03-2018 CO689_RS05720 c299e4c2cf8811ec538586f7169aa3e5 385 Gene3D G3DSA:3.90.190.20 253 384 0.0032 T 28-03-2018 CO689_RS05720 c299e4c2cf8811ec538586f7169aa3e5 385 TIGRFAM TIGR04012 poly_gGlu_PgsB: poly-gamma-glutamate synthase PgsB 3 380 2.2E-162 T 28-03-2018 IPR008337 Capsule biosynthesis protein CapB GO:0016020|GO:0045227 CO689_RS05720 c299e4c2cf8811ec538586f7169aa3e5 385 SUPERFAMILY SSF53623 104 236 4.58E-16 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CO689_RS05720 c299e4c2cf8811ec538586f7169aa3e5 385 SUPERFAMILY SSF53623 32 75 4.58E-16 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CO689_RS05720 c299e4c2cf8811ec538586f7169aa3e5 385 Gene3D G3DSA:3.40.1190.10 19 210 3.7E-16 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CO689_RS05720 c299e4c2cf8811ec538586f7169aa3e5 385 Pfam PF08245 Mur ligase middle domain 37 216 4.1E-10 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CO689_RS05720 c299e4c2cf8811ec538586f7169aa3e5 385 PRINTS PR01758 Capsule biosynthesis protein CapB signature 111 126 8.1E-74 T 28-03-2018 IPR008337 Capsule biosynthesis protein CapB GO:0016020|GO:0045227 CO689_RS05720 c299e4c2cf8811ec538586f7169aa3e5 385 PRINTS PR01758 Capsule biosynthesis protein CapB signature 360 376 8.1E-74 T 28-03-2018 IPR008337 Capsule biosynthesis protein CapB GO:0016020|GO:0045227 CO689_RS05720 c299e4c2cf8811ec538586f7169aa3e5 385 PRINTS PR01758 Capsule biosynthesis protein CapB signature 196 213 8.1E-74 T 28-03-2018 IPR008337 Capsule biosynthesis protein CapB GO:0016020|GO:0045227 CO689_RS05720 c299e4c2cf8811ec538586f7169aa3e5 385 PRINTS PR01758 Capsule biosynthesis protein CapB signature 34 50 8.1E-74 T 28-03-2018 IPR008337 Capsule biosynthesis protein CapB GO:0016020|GO:0045227 CO689_RS05720 c299e4c2cf8811ec538586f7169aa3e5 385 PRINTS PR01758 Capsule biosynthesis protein CapB signature 293 308 8.1E-74 T 28-03-2018 IPR008337 Capsule biosynthesis protein CapB GO:0016020|GO:0045227 CO689_RS05720 c299e4c2cf8811ec538586f7169aa3e5 385 PRINTS PR01758 Capsule biosynthesis protein CapB signature 140 155 8.1E-74 T 28-03-2018 IPR008337 Capsule biosynthesis protein CapB GO:0016020|GO:0045227 CO689_RS05720 c299e4c2cf8811ec538586f7169aa3e5 385 PRINTS PR01758 Capsule biosynthesis protein CapB signature 162 179 8.1E-74 T 28-03-2018 IPR008337 Capsule biosynthesis protein CapB GO:0016020|GO:0045227 CO689_RS05720 c299e4c2cf8811ec538586f7169aa3e5 385 PRINTS PR01758 Capsule biosynthesis protein CapB signature 57 74 8.1E-74 T 28-03-2018 IPR008337 Capsule biosynthesis protein CapB GO:0016020|GO:0045227 CO689_RS05720 c299e4c2cf8811ec538586f7169aa3e5 385 PRINTS PR01758 Capsule biosynthesis protein CapB signature 77 95 8.1E-74 T 28-03-2018 IPR008337 Capsule biosynthesis protein CapB GO:0016020|GO:0045227 CO689_RS05720 c299e4c2cf8811ec538586f7169aa3e5 385 PRINTS PR01758 Capsule biosynthesis protein CapB signature 258 275 8.1E-74 T 28-03-2018 IPR008337 Capsule biosynthesis protein CapB GO:0016020|GO:0045227 CO689_RS05025 be56b6b093b801d1aa9324a37265ccdd 130 TIGRFAM TIGR01518 g3p_cytidyltrns: glycerol-3-phosphate cytidylyltransferase 4 126 2.7E-60 T 28-03-2018 IPR006409 Glycerol-3-phosphate cytidylyltransferase GO:0005737|GO:0019350|GO:0046872|GO:0047348 CO689_RS05025 be56b6b093b801d1aa9324a37265ccdd 130 Pfam PF01467 Cytidylyltransferase-like 5 124 3.8E-24 T 28-03-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 CO689_RS05025 be56b6b093b801d1aa9324a37265ccdd 130 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 3 67 7.0E-23 T 28-03-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 CO689_RS05025 be56b6b093b801d1aa9324a37265ccdd 130 Gene3D G3DSA:3.40.50.620 1 127 7.4E-31 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CO689_RS05025 be56b6b093b801d1aa9324a37265ccdd 130 SUPERFAMILY SSF52374 1 125 6.66E-34 T 28-03-2018 CO689_RS05255 3726f9e2899ca7c06207e2d1750bfe0a 236 Pfam PF03475 3-alpha domain 180 221 6.2E-10 T 28-03-2018 IPR005163 3-alpha domain CO689_RS05255 3726f9e2899ca7c06207e2d1750bfe0a 236 SUPERFAMILY SSF50800 24 228 9.42E-63 T 28-03-2018 IPR011037 Pyruvate kinase-like, insert domain CO689_RS05255 3726f9e2899ca7c06207e2d1750bfe0a 236 Pfam PF03473 MOSC domain 58 169 3.9E-21 T 28-03-2018 IPR005302 Molybdenum cofactor sulfurase, C-terminal GO:0003824|GO:0030151|GO:0030170 CO689_RS05255 3726f9e2899ca7c06207e2d1750bfe0a 236 Gene3D G3DSA:2.40.33.20 4 235 1.6E-46 T 28-03-2018 CO689_RS00970 4116172fbb682a9694c9af6830d140d5 329 Gene3D G3DSA:3.40.50.2300 176 311 2.3E-33 T 28-03-2018 CO689_RS00970 4116172fbb682a9694c9af6830d140d5 329 Pfam PF00356 Bacterial regulatory proteins, lacI family 4 49 1.2E-19 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CO689_RS00970 4116172fbb682a9694c9af6830d140d5 329 SUPERFAMILY SSF47413 2 60 1.46E-18 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CO689_RS00970 4116172fbb682a9694c9af6830d140d5 329 Gene3D G3DSA:1.10.260.40 3 55 1.8E-23 T 28-03-2018 CO689_RS00970 4116172fbb682a9694c9af6830d140d5 329 SMART SM00354 2 72 6.1E-39 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CO689_RS00970 4116172fbb682a9694c9af6830d140d5 329 TIGRFAM TIGR01481 ccpA: catabolite control protein A 1 329 1.3E-155 T 28-03-2018 IPR006377 Catabolite control protein A GO:0006355 CO689_RS00970 4116172fbb682a9694c9af6830d140d5 329 Pfam PF13377 Periplasmic binding protein-like domain 169 328 8.5E-28 T 28-03-2018 CO689_RS00970 4116172fbb682a9694c9af6830d140d5 329 SUPERFAMILY SSF53822 62 329 3.46E-69 T 28-03-2018 IPR028082 Periplasmic binding protein-like I CO689_RS00970 4116172fbb682a9694c9af6830d140d5 329 Gene3D G3DSA:3.40.50.2300 56 175 2.3E-34 T 28-03-2018 CO689_RS00970 4116172fbb682a9694c9af6830d140d5 329 ProSitePatterns PS00356 LacI-type HTH domain signature. 5 23 - T 28-03-2018 CO689_RS00970 4116172fbb682a9694c9af6830d140d5 329 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 4 14 1.5E-5 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CO689_RS00970 4116172fbb682a9694c9af6830d140d5 329 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 14 24 1.5E-5 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CO689_RS04500 7a680a203efb72dc697cd9b9655af263 319 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 24 301 1.1E-86 T 28-03-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 CO689_RS04500 7a680a203efb72dc697cd9b9655af263 319 SUPERFAMILY SSF161111 22 221 3.27E-58 T 28-03-2018 CO689_RS04500 7a680a203efb72dc697cd9b9655af263 319 SUPERFAMILY SSF160240 226 301 2.35E-9 T 28-03-2018 CO689_RS04500 7a680a203efb72dc697cd9b9655af263 319 Gene3D G3DSA:1.20.1510.10 22 220 5.5E-59 T 28-03-2018 CO689_RS04500 7a680a203efb72dc697cd9b9655af263 319 Pfam PF01545 Cation efflux family 27 220 7.9E-51 T 28-03-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 CO689_RS04500 7a680a203efb72dc697cd9b9655af263 319 Gene3D G3DSA:3.30.70.1350 222 303 1.2E-11 T 28-03-2018 IPR027470 Cation efflux protein, cytoplasmic domain CO689_RS02105 64f9c9a8d1e12a8f8a937874ee992fb9 266 Gene3D G3DSA:3.60.110.10 1 263 6.4E-74 T 28-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CO689_RS02105 64f9c9a8d1e12a8f8a937874ee992fb9 266 Pfam PF00795 Carbon-nitrogen hydrolase 13 248 5.5E-43 T 28-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CO689_RS02105 64f9c9a8d1e12a8f8a937874ee992fb9 266 SUPERFAMILY SSF56317 1 263 2.49E-69 T 28-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CO689_RS02600 e275152b27f19e663b0de0d6d558104a 155 ProDom PD013172 LYASE SYNTHESIS LUXS AUTOINDUCER-2 PRODUCTION AUTOINDUCER S-RIBOSYLHOMOCYSTEINE AI-2 QUORUM SENSING 10 143 1.0E-68 T 28-03-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 CO689_RS02600 e275152b27f19e663b0de0d6d558104a 155 PRINTS PR01487 Bacterial autoinducer-2 (AI-2) production protein LuxS signature 7 25 8.6E-43 T 28-03-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 CO689_RS02600 e275152b27f19e663b0de0d6d558104a 155 PRINTS PR01487 Bacterial autoinducer-2 (AI-2) production protein LuxS signature 75 93 8.6E-43 T 28-03-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 CO689_RS02600 e275152b27f19e663b0de0d6d558104a 155 PRINTS PR01487 Bacterial autoinducer-2 (AI-2) production protein LuxS signature 51 69 8.6E-43 T 28-03-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 CO689_RS02600 e275152b27f19e663b0de0d6d558104a 155 PRINTS PR01487 Bacterial autoinducer-2 (AI-2) production protein LuxS signature 30 48 8.6E-43 T 28-03-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 CO689_RS02600 e275152b27f19e663b0de0d6d558104a 155 PRINTS PR01487 Bacterial autoinducer-2 (AI-2) production protein LuxS signature 116 135 8.6E-43 T 28-03-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 CO689_RS02600 e275152b27f19e663b0de0d6d558104a 155 Gene3D G3DSA:3.30.1360.80 5 152 3.0E-59 T 28-03-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 CO689_RS02600 e275152b27f19e663b0de0d6d558104a 155 Hamap MF_00091 S-ribosylhomocysteine lyase [luxS]. 3 153 34.356 T 28-03-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 CO689_RS02600 e275152b27f19e663b0de0d6d558104a 155 Pfam PF02664 S-Ribosylhomocysteinase (LuxS) 5 148 5.0E-56 T 28-03-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 CO689_RS02600 e275152b27f19e663b0de0d6d558104a 155 PIRSF PIRSF006160 3 154 7.0E-66 T 28-03-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 CO689_RS02600 e275152b27f19e663b0de0d6d558104a 155 SUPERFAMILY SSF63411 3 151 4.21E-63 T 28-03-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 CO689_RS07135 85b4b0883e74cee0b0072ae8c94d4845 85 Gene3D G3DSA:2.10.260.10 2 85 3.0E-13 T 28-03-2018 CO689_RS07135 85b4b0883e74cee0b0072ae8c94d4845 85 SUPERFAMILY SSF89447 6 58 1.1E-9 T 28-03-2018 CO689_RS01350 e687e69f91f733115582070427e28a1a 156 Gene3D G3DSA:1.20.1480.30 21 115 1.7E-5 T 28-03-2018 CO689_RS05315 5d27b3915b6dc86513e3f5e490d6fc9a 509 Pfam PF01943 Polysaccharide biosynthesis protein 7 293 3.7E-17 T 28-03-2018 IPR002797 Polysaccharide biosynthesis protein GO:0016020 CO689_RS05315 5d27b3915b6dc86513e3f5e490d6fc9a 509 Pfam PF14667 Polysaccharide biosynthesis C-terminal domain 349 487 2.0E-9 T 28-03-2018 IPR029303 Polysaccharide biosynthesis protein, C-terminal domain CO689_RS08850 233f2ac7ba3612ff47d826fe3489a3d2 228 SMART SM00448 2 112 4.6E-38 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CO689_RS08850 233f2ac7ba3612ff47d826fe3489a3d2 228 Pfam PF00486 Transcriptional regulatory protein, C terminal 149 223 3.1E-24 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CO689_RS08850 233f2ac7ba3612ff47d826fe3489a3d2 228 Gene3D G3DSA:1.10.10.10 123 228 4.6E-29 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS08850 233f2ac7ba3612ff47d826fe3489a3d2 228 Gene3D G3DSA:3.40.50.2300 2 122 9.4E-35 T 28-03-2018 CO689_RS08850 233f2ac7ba3612ff47d826fe3489a3d2 228 SUPERFAMILY SSF52172 3 182 2.34E-38 T 28-03-2018 IPR011006 CheY-like superfamily CO689_RS08850 233f2ac7ba3612ff47d826fe3489a3d2 228 SMART SM00862 147 223 5.5E-22 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CO689_RS08850 233f2ac7ba3612ff47d826fe3489a3d2 228 Pfam PF00072 Response regulator receiver domain 4 111 5.2E-30 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CO689_RS02860 f3375c9f3ad497b3a920ce1426f13efa 356 Gene3D G3DSA:3.20.20.10 1 232 6.2E-21 T 28-03-2018 IPR029066 PLP-binding barrel CO689_RS02860 f3375c9f3ad497b3a920ce1426f13efa 356 Pfam PF01168 Alanine racemase, N-terminal domain 6 220 4.9E-18 T 28-03-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CO689_RS02860 f3375c9f3ad497b3a920ce1426f13efa 356 SUPERFAMILY SSF51419 7 225 1.47E-22 T 28-03-2018 IPR029066 PLP-binding barrel CO689_RS06425 3e7a23a1cab9f0df719e91089c1f3537 269 Pfam PF01380 SIS domain 115 239 2.5E-15 T 28-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 CO689_RS06425 3e7a23a1cab9f0df719e91089c1f3537 269 SUPERFAMILY SSF46689 1 77 1.11E-14 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CO689_RS06425 3e7a23a1cab9f0df719e91089c1f3537 269 Pfam PF01418 Helix-turn-helix domain, rpiR family 1 76 6.4E-13 T 28-03-2018 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 CO689_RS06425 3e7a23a1cab9f0df719e91089c1f3537 269 SUPERFAMILY SSF53697 85 245 1.03E-33 T 28-03-2018 CO689_RS06425 3e7a23a1cab9f0df719e91089c1f3537 269 Gene3D G3DSA:3.40.50.10490 67 269 1.2E-31 T 28-03-2018 CO689_RS06425 3e7a23a1cab9f0df719e91089c1f3537 269 Gene3D G3DSA:1.10.10.10 1 66 8.3E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS04895 3daae5f6cb8ffe654373c4c17b50cfea 342 SUPERFAMILY SSF69572 3 330 2.75E-71 T 28-03-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 CO689_RS04895 3daae5f6cb8ffe654373c4c17b50cfea 342 Gene3D G3DSA:3.40.50.720 7 253 1.8E-57 T 28-03-2018 CO689_RS04895 3daae5f6cb8ffe654373c4c17b50cfea 342 Pfam PF00899 ThiF family 14 249 2.8E-53 T 28-03-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 CO689_RS06390 e64811ec16ab342047297be3bbe059c8 103 Pfam PF05154 TM2 domain 18 73 4.7E-13 T 28-03-2018 IPR007829 TM2 domain CO689_RS11485 3b2f43fcc21ad1baf970978b6042e1ec 62 Pfam PF00830 Ribosomal L28 family 3 58 3.1E-19 T 28-03-2018 IPR026569 Ribosomal protein L28/L24 GO:0003735 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CO689_RS11485 3b2f43fcc21ad1baf970978b6042e1ec 62 SUPERFAMILY SSF143800 1 60 3.53E-23 T 28-03-2018 IPR034704 L28p-like Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CO689_RS11485 3b2f43fcc21ad1baf970978b6042e1ec 62 Gene3D G3DSA:2.30.170.40 2 61 8.3E-19 T 28-03-2018 IPR026569 Ribosomal protein L28/L24 GO:0003735 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CO689_RS11485 3b2f43fcc21ad1baf970978b6042e1ec 62 Hamap MF_00373 50S ribosomal protein L28 [rpmB]. 1 62 18.51 T 28-03-2018 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CO689_RS11485 3b2f43fcc21ad1baf970978b6042e1ec 62 TIGRFAM TIGR00009 L28: ribosomal protein bL28 1 56 4.0E-21 T 28-03-2018 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CO689_RS02305 5f077b3b38acceabb1d497a7610768ec 154 Pfam PF03703 Bacterial PH domain 68 140 1.6E-9 T 28-03-2018 IPR005182 Domain of unknown function DUF304 CO689_RS10380 f044c5a7a9f2b9597656c28087477031 331 Gene3D G3DSA:3.90.1150.10 243 324 1.3E-6 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CO689_RS10380 f044c5a7a9f2b9597656c28087477031 331 Pfam PF00155 Aminotransferase class I and II 9 280 8.1E-36 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CO689_RS10380 f044c5a7a9f2b9597656c28087477031 331 SUPERFAMILY SSF53383 10 324 1.88E-53 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CO689_RS10380 f044c5a7a9f2b9597656c28087477031 331 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 183 192 - T 28-03-2018 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0008152|GO:0016740 CO689_RS10380 f044c5a7a9f2b9597656c28087477031 331 Gene3D G3DSA:3.40.640.10 13 242 3.9E-33 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CO689_RS03925 fdc488a5e85e06325bc2ceb9206079ca 399 Pfam PF01098 Cell cycle protein 18 379 7.1E-97 T 28-03-2018 IPR001182 Probable peptidoglycan glycosyltransferase FtsW/RodA GO:0016021|GO:0051301 CO689_RS00525 28505cc0f4726f8302bf4e02caa0de79 466 Gene3D G3DSA:1.20.1250.20 257 464 1.4E-23 T 28-03-2018 CO689_RS00525 28505cc0f4726f8302bf4e02caa0de79 466 SUPERFAMILY SSF103473 29 457 9.55E-49 T 28-03-2018 IPR020846 Major facilitator superfamily domain CO689_RS00525 28505cc0f4726f8302bf4e02caa0de79 466 Gene3D G3DSA:1.20.1250.20 9 256 7.1E-24 T 28-03-2018 CO689_RS00525 28505cc0f4726f8302bf4e02caa0de79 466 Pfam PF07690 Major Facilitator Superfamily 37 419 5.3E-30 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CO689_RS10570 03e36808967d5e5035ff200c72f947e1 156 ProDom PD034207 SA0907 SIMILAR ORF2 TRANSCRIPTIONAL AUTOLYSIN SAV1055 MW0938 ATLR CDS REGULATOR 1 155 6.0E-79 T 28-03-2018 IPR024469 Protein of unknown function DUF2538 CO689_RS10570 03e36808967d5e5035ff200c72f947e1 156 Pfam PF10804 Protein of unknown function (DUF2538) 1 155 9.5E-92 T 28-03-2018 IPR024469 Protein of unknown function DUF2538 CO689_RS08705 466dd968cdb4410d870a7390c8975310 228 SUPERFAMILY SSF158560 6 97 4.45E-7 T 28-03-2018 CO689_RS08705 466dd968cdb4410d870a7390c8975310 228 Gene3D G3DSA:1.10.1900.10 14 100 9.9E-10 T 28-03-2018 CO689_RS08705 466dd968cdb4410d870a7390c8975310 228 Pfam PF06570 Protein of unknown function (DUF1129) 39 219 8.4E-10 T 28-03-2018 IPR009214 Protein of unknown function DUF1129 CO689_RS11315 e27beb874926263199726df18d6875dd 105 SUPERFAMILY SSF143430 5 85 1.02E-11 T 28-03-2018 CO689_RS11315 e27beb874926263199726df18d6875dd 105 Gene3D G3DSA:3.30.70.240 1 99 7.1E-14 T 28-03-2018 CO689_RS11315 e27beb874926263199726df18d6875dd 105 TIGRFAM TIGR01573 cas2: CRISPR-associated endonuclease Cas2 5 94 2.6E-18 T 28-03-2018 IPR021127 CRISPR-associated endonuclease Cas2 GO:0004521|GO:0043571 CO689_RS11315 e27beb874926263199726df18d6875dd 105 Hamap MF_01471 CRISPR-associated endoribonuclease Cas2 [cas2]. 4 103 12.095 T 28-03-2018 IPR021127 CRISPR-associated endonuclease Cas2 GO:0004521|GO:0043571 CO689_RS11315 e27beb874926263199726df18d6875dd 105 Pfam PF09827 CRISPR associated protein Cas2 6 83 3.2E-13 T 28-03-2018 IPR019199 Virulence-associated protein D / CRISPR associated protein Cas2 CO689_RS10540 8c26b0d1e345e8cdcd3bb451265a3a12 148 Pfam PF01047 MarR family 40 95 5.0E-11 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CO689_RS10540 8c26b0d1e345e8cdcd3bb451265a3a12 148 SUPERFAMILY SSF46785 8 139 2.55E-30 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS10540 8c26b0d1e345e8cdcd3bb451265a3a12 148 SMART SM00347 30 128 1.3E-19 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CO689_RS10540 8c26b0d1e345e8cdcd3bb451265a3a12 148 Gene3D G3DSA:1.10.10.10 6 131 1.7E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS11440 b1a43033e08601331cd22d94ea6276a4 162 Gene3D G3DSA:3.90.45.10 1 161 1.8E-37 T 28-03-2018 IPR023635 Peptide deformylase CO689_RS11440 b1a43033e08601331cd22d94ea6276a4 162 PRINTS PR01576 Peptide deformylase signature 100 118 6.8E-16 T 28-03-2018 IPR023635 Peptide deformylase CO689_RS11440 b1a43033e08601331cd22d94ea6276a4 162 PRINTS PR01576 Peptide deformylase signature 88 99 6.8E-16 T 28-03-2018 IPR023635 Peptide deformylase CO689_RS11440 b1a43033e08601331cd22d94ea6276a4 162 PRINTS PR01576 Peptide deformylase signature 33 62 6.8E-16 T 28-03-2018 IPR023635 Peptide deformylase CO689_RS11440 b1a43033e08601331cd22d94ea6276a4 162 PRINTS PR01576 Peptide deformylase signature 119 148 6.8E-16 T 28-03-2018 IPR023635 Peptide deformylase CO689_RS11440 b1a43033e08601331cd22d94ea6276a4 162 PIRSF PIRSF004749 1 162 1.6E-39 T 28-03-2018 IPR023635 Peptide deformylase CO689_RS11440 b1a43033e08601331cd22d94ea6276a4 162 Hamap MF_00163 Peptide deformylase [def]. 2 158 20.175 T 28-03-2018 IPR023635 Peptide deformylase CO689_RS11440 b1a43033e08601331cd22d94ea6276a4 162 SUPERFAMILY SSF56420 3 155 6.41E-37 T 28-03-2018 IPR023635 Peptide deformylase CO689_RS11440 b1a43033e08601331cd22d94ea6276a4 162 Pfam PF01327 Polypeptide deformylase 4 149 5.8E-36 T 28-03-2018 IPR023635 Peptide deformylase CO689_RS09070 c62a04e626f5f7aa5581102455f9c312 354 Pfam PF07694 5TMR of 5TMR-LYT 16 173 2.0E-10 T 28-03-2018 IPR011620 Signal transduction histidine kinase, 5TM receptor LytS, transmembrane region GO:0000155|GO:0000160|GO:0004673|GO:0016021|GO:0071555 CO689_RS09070 c62a04e626f5f7aa5581102455f9c312 354 SUPERFAMILY SSF55073 192 349 7.45E-36 T 28-03-2018 IPR029787 Nucleotide cyclase CO689_RS09070 c62a04e626f5f7aa5581102455f9c312 354 Gene3D G3DSA:3.30.70.270 175 350 2.4E-41 T 28-03-2018 CO689_RS09070 c62a04e626f5f7aa5581102455f9c312 354 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 186 349 6.8E-39 T 28-03-2018 IPR000160 GGDEF domain CO689_RS09070 c62a04e626f5f7aa5581102455f9c312 354 Pfam PF00990 Diguanylate cyclase, GGDEF domain 189 346 4.9E-34 T 28-03-2018 IPR000160 GGDEF domain CO689_RS09070 c62a04e626f5f7aa5581102455f9c312 354 SMART SM00267 176 350 7.8E-41 T 28-03-2018 IPR000160 GGDEF domain CO689_RS04715 23bf72a070c963810f47a03d4900b8f6 348 Pfam PF03786 D-mannonate dehydratase (UxuA) 1 345 2.7E-154 T 28-03-2018 IPR004628 Mannonate dehydratase GO:0006064|GO:0008927 KEGG: 00040+4.2.1.8|MetaCyc: PWY-7242 CO689_RS04715 23bf72a070c963810f47a03d4900b8f6 348 Hamap MF_00106 Mannonate dehydratase [uxuA]. 1 348 173.726 T 28-03-2018 IPR004628 Mannonate dehydratase GO:0006064|GO:0008927 KEGG: 00040+4.2.1.8|MetaCyc: PWY-7242 CO689_RS04715 23bf72a070c963810f47a03d4900b8f6 348 PIRSF PIRSF016049 1 144 9.2E-51 T 28-03-2018 IPR004628 Mannonate dehydratase GO:0006064|GO:0008927 KEGG: 00040+4.2.1.8|MetaCyc: PWY-7242 CO689_RS04715 23bf72a070c963810f47a03d4900b8f6 348 PIRSF PIRSF016049 143 348 5.8E-79 T 28-03-2018 IPR004628 Mannonate dehydratase GO:0006064|GO:0008927 KEGG: 00040+4.2.1.8|MetaCyc: PWY-7242 CO689_RS04715 23bf72a070c963810f47a03d4900b8f6 348 SUPERFAMILY SSF51658 1 341 1.21E-90 T 28-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain CO689_RS04715 23bf72a070c963810f47a03d4900b8f6 348 TIGRFAM TIGR00695 uxuA: mannonate dehydratase 1 137 2.1E-61 T 28-03-2018 IPR004628 Mannonate dehydratase GO:0006064|GO:0008927 KEGG: 00040+4.2.1.8|MetaCyc: PWY-7242 CO689_RS04715 23bf72a070c963810f47a03d4900b8f6 348 TIGRFAM TIGR00695 uxuA: mannonate dehydratase 145 345 2.4E-61 T 28-03-2018 IPR004628 Mannonate dehydratase GO:0006064|GO:0008927 KEGG: 00040+4.2.1.8|MetaCyc: PWY-7242 CO689_RS04715 23bf72a070c963810f47a03d4900b8f6 348 Gene3D G3DSA:3.20.20.150 1 348 1.2E-111 T 28-03-2018 CO689_RS05005 7d572e2250b30035637299df27c9ec45 311 Pfam PF08546 Ketopantoate reductase PanE/ApbA C terminal 180 305 1.0E-28 T 28-03-2018 IPR013752 Ketopantoate reductase, C-terminal domain GO:0016491|GO:0050661|GO:0055114 KEGG: 00052+1.1.1.16|KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654|MetaCyc: PWY-7862 CO689_RS05005 7d572e2250b30035637299df27c9ec45 311 Gene3D G3DSA:1.10.1040.10 179 311 2.9E-30 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CO689_RS05005 7d572e2250b30035637299df27c9ec45 311 Pfam PF02558 Ketopantoate reductase PanE/ApbA 3 153 1.8E-34 T 28-03-2018 IPR013332 Ketopantoate reductase, N-terminal domain GO:0008677|GO:0055114 KEGG: 00052+1.1.1.16|KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654|MetaCyc: PWY-7862 CO689_RS05005 7d572e2250b30035637299df27c9ec45 311 TIGRFAM TIGR00745 apbA_panE: 2-dehydropantoate 2-reductase 2 305 5.9E-69 T 28-03-2018 IPR003710 Ketopantoate reductase ApbA/PanE GO:0005737|GO:0015940|GO:0016491|GO:0055114 KEGG: 00052+1.1.1.16|KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654|MetaCyc: PWY-7862 CO689_RS05005 7d572e2250b30035637299df27c9ec45 311 SUPERFAMILY SSF48179 180 306 3.74E-28 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CO689_RS05005 7d572e2250b30035637299df27c9ec45 311 SUPERFAMILY SSF51735 1 136 2.22E-15 T 28-03-2018 IPR016040 NAD(P)-binding domain CO689_RS05005 7d572e2250b30035637299df27c9ec45 311 Gene3D G3DSA:3.40.50.720 1 178 9.5E-28 T 28-03-2018 CO689_RS03295 a6aa78ac0e25a4e3e1f8817022e0371e 160 Pfam PF03205 Molybdopterin guanine dinucleotide synthesis protein B 2 119 1.2E-27 T 28-03-2018 IPR004435 Molybdopterin-guanine dinucleotide biosynthesis protein B (MobB) domain GO:0005525|GO:0006777 CO689_RS03295 a6aa78ac0e25a4e3e1f8817022e0371e 160 SUPERFAMILY SSF52540 2 127 3.1E-15 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CO689_RS03295 a6aa78ac0e25a4e3e1f8817022e0371e 160 Gene3D G3DSA:3.40.50.300 1 156 3.7E-18 T 28-03-2018 CO689_RS03295 a6aa78ac0e25a4e3e1f8817022e0371e 160 TIGRFAM TIGR00176 mobB: molybdopterin-guanine dinucleotide biosynthesis protein B 2 150 1.0E-42 T 28-03-2018 IPR004435 Molybdopterin-guanine dinucleotide biosynthesis protein B (MobB) domain GO:0005525|GO:0006777 CO689_RS09710 6604654648a10d352d5815721460fed5 132 Gene3D G3DSA:1.10.1270.10 23 129 3.4E-5 T 28-03-2018 CO689_RS09355 44dffd1f272e26207e705569a2821ef8 78 TIGRFAM TIGR00810 secG: preprotein translocase, SecG subunit 3 77 4.8E-24 T 28-03-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 CO689_RS09355 44dffd1f272e26207e705569a2821ef8 78 Pfam PF03840 Preprotein translocase SecG subunit 4 76 8.7E-24 T 28-03-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 CO689_RS09355 44dffd1f272e26207e705569a2821ef8 78 PRINTS PR01651 Protein-export SecG membrane protein signature 57 78 8.9E-11 T 28-03-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 CO689_RS09355 44dffd1f272e26207e705569a2821ef8 78 PRINTS PR01651 Protein-export SecG membrane protein signature 23 37 8.9E-11 T 28-03-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 CO689_RS09355 44dffd1f272e26207e705569a2821ef8 78 PRINTS PR01651 Protein-export SecG membrane protein signature 3 23 8.9E-11 T 28-03-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 CO689_RS04390 26b47bcac5e3aa6da1c521469f475de9 341 TIGRFAM TIGR00802 nico: transition metal uptake transporter, Ni2+-Co2+ transporter (NiCoT) family 46 323 2.9E-114 T 28-03-2018 IPR004688 Transition metal uptake transporter nickel/cobalt GO:0015099|GO:0016021|GO:0035444|GO:0046872 CO689_RS04390 26b47bcac5e3aa6da1c521469f475de9 341 Pfam PF03824 High-affinity nickel-transport protein 43 327 4.4E-91 T 28-03-2018 IPR011541 Nickel/cobalt transporter, high-affinity GO:0015099|GO:0016021|GO:0035444|GO:0046872 CO689_RS07585 b1f03d662da6172935190ed53bbc301f 123 PIRSF PIRSF021439 1 122 8.2E-28 T 28-03-2018 IPR010377 Initiation control protein YabA GO:0006260 CO689_RS07585 b1f03d662da6172935190ed53bbc301f 123 Pfam PF06156 Initiation control protein YabA 2 116 4.5E-29 T 28-03-2018 IPR010377 Initiation control protein YabA GO:0006260 CO689_RS04600 358c93d4867c8b002bf7a8f825eb63ea 664 TIGRFAM TIGR00437 feoB: ferrous iron transport protein B 9 631 1.7E-188 T 28-03-2018 IPR003373 Ferrous iron transport protein B GO:0005525|GO:0015093|GO:0015684|GO:0016021 CO689_RS04600 358c93d4867c8b002bf7a8f825eb63ea 664 Pfam PF07664 Ferrous iron transport protein B C terminus 454 506 1.0E-20 T 28-03-2018 IPR011640 Ferrous iron transport protein B, C-terminal GO:0015093|GO:0015684|GO:0016021 CO689_RS04600 358c93d4867c8b002bf7a8f825eb63ea 664 Gene3D G3DSA:3.40.50.300 4 326 3.0E-29 T 28-03-2018 CO689_RS04600 358c93d4867c8b002bf7a8f825eb63ea 664 Pfam PF07670 Nucleoside recognition 511 635 1.6E-31 T 28-03-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 CO689_RS04600 358c93d4867c8b002bf7a8f825eb63ea 664 Pfam PF07670 Nucleoside recognition 350 443 9.8E-15 T 28-03-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 CO689_RS04600 358c93d4867c8b002bf7a8f825eb63ea 664 SUPERFAMILY SSF52540 6 162 1.39E-32 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CO689_RS04600 358c93d4867c8b002bf7a8f825eb63ea 664 Pfam PF02421 Ferrous iron transport protein B 5 154 2.9E-57 T 28-03-2018 IPR030389 FeoB-type guanine nucleotide-binding (G) domain GO:0005525 CO689_RS04600 358c93d4867c8b002bf7a8f825eb63ea 664 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 26 44 9.3E-7 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CO689_RS04600 358c93d4867c8b002bf7a8f825eb63ea 664 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 51 66 9.3E-7 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CO689_RS04600 358c93d4867c8b002bf7a8f825eb63ea 664 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 5 25 9.3E-7 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CO689_RS02915 595c69effd4d07b16c0e3f70d714f840 295 SUPERFAMILY SSF53474 48 247 5.63E-9 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CO689_RS02915 595c69effd4d07b16c0e3f70d714f840 295 Pfam PF06028 Alpha/beta hydrolase of unknown function (DUF915) 41 291 5.4E-78 T 28-03-2018 IPR010315 Protein of unknown function DUF915, hydrolase-like CO689_RS02915 595c69effd4d07b16c0e3f70d714f840 295 Gene3D G3DSA:3.40.50.1820 43 291 3.8E-16 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CO689_RS12605 9ba046003637aca4132f185f473c297a 175 TIGRFAM TIGR00401 msrA: peptide-methionine (S)-S-oxide reductase 4 153 1.7E-57 T 28-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 CO689_RS12605 9ba046003637aca4132f185f473c297a 175 Gene3D G3DSA:3.30.1060.10 1 170 5.5E-63 T 28-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 CO689_RS12605 9ba046003637aca4132f185f473c297a 175 Pfam PF01625 Peptide methionine sulfoxide reductase 4 154 1.2E-58 T 28-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 CO689_RS12605 9ba046003637aca4132f185f473c297a 175 SUPERFAMILY SSF55068 2 165 2.75E-68 T 28-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 CO689_RS12605 9ba046003637aca4132f185f473c297a 175 Hamap MF_01401 Peptide methionine sulfoxide reductase MsrA [msrA]. 1 160 36.476 T 28-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 CO689_RS13760 18e4d822349ef73fa92b3d9fb032cb3d 175 SUPERFAMILY SSF55200 86 174 4.97E-33 T 28-03-2018 IPR019815 Translation initiation factor 3, C-terminal GO:0006413 Reactome: R-HSA-5368286 CO689_RS13760 18e4d822349ef73fa92b3d9fb032cb3d 175 TIGRFAM TIGR00168 infC: translation initiation factor IF-3 11 173 1.4E-70 T 28-03-2018 IPR001288 Translation initiation factor 3 GO:0003743|GO:0006413 Reactome: R-HSA-5368286 CO689_RS13760 18e4d822349ef73fa92b3d9fb032cb3d 175 Gene3D G3DSA:3.10.20.80 6 82 1.4E-31 T 28-03-2018 CO689_RS13760 18e4d822349ef73fa92b3d9fb032cb3d 175 SUPERFAMILY SSF54364 9 82 3.79E-29 T 28-03-2018 IPR019814 Translation initiation factor 3, N-terminal GO:0003743|GO:0006413 Reactome: R-HSA-5368286 CO689_RS13760 18e4d822349ef73fa92b3d9fb032cb3d 175 Pfam PF05198 Translation initiation factor IF-3, N-terminal domain 11 79 2.1E-31 T 28-03-2018 IPR019814 Translation initiation factor 3, N-terminal GO:0003743|GO:0006413 Reactome: R-HSA-5368286 CO689_RS13760 18e4d822349ef73fa92b3d9fb032cb3d 175 Gene3D G3DSA:3.30.110.10 83 175 1.7E-35 T 28-03-2018 CO689_RS13760 18e4d822349ef73fa92b3d9fb032cb3d 175 Pfam PF00707 Translation initiation factor IF-3, C-terminal domain 87 171 1.4E-38 T 28-03-2018 IPR019815 Translation initiation factor 3, C-terminal GO:0006413 Reactome: R-HSA-5368286 CO689_RS13760 18e4d822349ef73fa92b3d9fb032cb3d 175 Hamap MF_00080 Translation initiation factor IF-3 [infC]. 4 174 30.539 T 28-03-2018 IPR001288 Translation initiation factor 3 GO:0003743|GO:0006413 Reactome: R-HSA-5368286 CO689_RS13760 18e4d822349ef73fa92b3d9fb032cb3d 175 ProSitePatterns PS00938 Initiation factor 3 signature. 62 75 - T 28-03-2018 IPR019813 Translation initiation factor 3, conserved site GO:0003743|GO:0006413 CO689_RS07060 cacdf9444b0b2b1171a787281531774f 302 Gene3D G3DSA:3.90.176.10 38 211 4.9E-4 T 28-03-2018 CO689_RS05145 8d9b897b732b4eb25662afd6e6843c3e 232 Gene3D G3DSA:3.40.190.10 1 215 8.5E-8 T 28-03-2018 CO689_RS07255 ef8f39ba8ff8cbb308a2fc27f49e6f5b 259 Gene3D G3DSA:3.10.180.10 3 64 4.6E-7 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CO689_RS07255 ef8f39ba8ff8cbb308a2fc27f49e6f5b 259 Gene3D G3DSA:3.10.180.10 65 223 4.8E-27 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CO689_RS07255 ef8f39ba8ff8cbb308a2fc27f49e6f5b 259 SUPERFAMILY SSF54593 163 222 1.88E-11 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CO689_RS07255 ef8f39ba8ff8cbb308a2fc27f49e6f5b 259 SUPERFAMILY SSF54593 3 165 1.65E-31 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CO689_RS07255 ef8f39ba8ff8cbb308a2fc27f49e6f5b 259 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 11 123 4.8E-13 T 28-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CO689_RS03770 c24179fd54fe1ba9f4cfd9df7551ca1a 184 SUPERFAMILY SSF46689 6 66 4.73E-11 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CO689_RS03770 c24179fd54fe1ba9f4cfd9df7551ca1a 184 Gene3D G3DSA:1.10.10.60 44 174 4.3E-6 T 28-03-2018 CO689_RS03770 c24179fd54fe1ba9f4cfd9df7551ca1a 184 Gene3D G3DSA:1.10.10.60 3 43 1.1E-8 T 28-03-2018 CO689_RS03770 c24179fd54fe1ba9f4cfd9df7551ca1a 184 Pfam PF14278 Transcriptional regulator C-terminal region 86 159 5.0E-7 T 28-03-2018 CO689_RS03770 c24179fd54fe1ba9f4cfd9df7551ca1a 184 Pfam PF00440 Bacterial regulatory proteins, tetR family 21 55 1.6E-6 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CO689_RS05605 8c050dcdf54fafc2b590394afffc185d 345 Pfam PF11611 Domain of unknown function (DUF4352) 44 154 1.1E-14 T 28-03-2018 IPR029051 Domain of unknown function DUF4352 CO689_RS05605 8c050dcdf54fafc2b590394afffc185d 345 Gene3D G3DSA:2.60.40.1240 37 165 3.3E-20 T 28-03-2018 IPR029050 Immunoprotective extracellular, immunoglobulin-like domain CO689_RS02415 32c66e724573454d72a891f3e9d19f9d 147 Pfam PF14183 YwpF-like protein 2 132 2.5E-44 T 28-03-2018 IPR025573 YwpF-like protein CO689_RS09410 6ab4b9aec218ecf2c1335052d4bf4163 193 Gene3D G3DSA:1.20.1440.20 17 187 5.3E-62 T 28-03-2018 CO689_RS09410 6ab4b9aec218ecf2c1335052d4bf4163 193 SUPERFAMILY SSF140478 29 176 1.14E-56 T 28-03-2018 IPR023353 LemA-like domain CO689_RS09410 6ab4b9aec218ecf2c1335052d4bf4163 193 Pfam PF04011 LemA family 10 187 2.3E-73 T 28-03-2018 IPR007156 LemA CO689_RS13420 c72b5dafe106bbf9f604a09068284928 103 Hamap MF_01448 UPF0473 protein . 17 103 16.338 T 28-03-2018 IPR009711 Uncharacterised protein family UPF0473 CO689_RS13420 c72b5dafe106bbf9f604a09068284928 103 Pfam PF06949 Protein of unknown function (DUF1292) 26 103 9.4E-10 T 28-03-2018 IPR009711 Uncharacterised protein family UPF0473 CO689_RS02170 bade021e0c14397add74b5d76e611792 221 SUPERFAMILY SSF53067 110 205 2.07E-10 T 28-03-2018 CO689_RS02170 bade021e0c14397add74b5d76e611792 221 SUPERFAMILY SSF53067 3 103 2.94E-29 T 28-03-2018 CO689_RS02170 bade021e0c14397add74b5d76e611792 221 Gene3D G3DSA:3.30.420.40 1 139 2.7E-36 T 28-03-2018 CO689_RS02170 bade021e0c14397add74b5d76e611792 221 Pfam PF00814 Glycoprotease family 31 154 8.2E-32 T 28-03-2018 IPR000905 Gcp-like domain KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CO689_RS02170 bade021e0c14397add74b5d76e611792 221 TIGRFAM TIGR03725 T6A_YeaZ: tRNA threonylcarbamoyl adenosine modification protein YeaZ 4 206 2.5E-52 T 28-03-2018 IPR022496 tRNA threonylcarbamoyl adenosine modification protein TsaB GO:0002949 CO689_RS03705 cfee7042055ce4dd428835d36c8a0c6f 177 Pfam PF05656 Protein of unknown function (DUF805) 14 140 1.4E-11 T 28-03-2018 IPR008523 Protein of unknown function DUF805 GO:0016021 CO689_RS05985 6354931db4f0a0fc4e96952cde321a1e 485 Pfam PF02554 Carbon starvation protein CstA 3 207 4.6E-33 T 28-03-2018 IPR003706 CstA, N-terminal domain GO:0009267|GO:0016020 CO689_RS05985 6354931db4f0a0fc4e96952cde321a1e 485 Pfam PF13722 5TM C-terminal transporter carbon starvation CstA 317 424 2.6E-19 T 28-03-2018 IPR025299 CstA, C-terminal domain CO689_RS12765 e2c8ca09f7d9edd1ddab95d5789f7ff6 432 Gene3D G3DSA:3.65.10.10 22 216 2.0E-40 T 28-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 CO689_RS12765 e2c8ca09f7d9edd1ddab95d5789f7ff6 432 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 10 423 2.4E-121 T 28-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 CO689_RS12765 e2c8ca09f7d9edd1ddab95d5789f7ff6 432 ProSitePatterns PS00104 EPSP synthase signature 1. 89 103 - T 28-03-2018 IPR023193 3-phosphoshikimate 1-carboxyvinyltransferase, conserved site KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 CO689_RS12765 e2c8ca09f7d9edd1ddab95d5789f7ff6 432 PIRSF PIRSF000505 2 432 9.3E-105 T 28-03-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 CO689_RS12765 e2c8ca09f7d9edd1ddab95d5789f7ff6 432 ProSitePatterns PS00885 EPSP synthase signature 2. 342 360 - T 28-03-2018 IPR023193 3-phosphoshikimate 1-carboxyvinyltransferase, conserved site KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 CO689_RS12765 e2c8ca09f7d9edd1ddab95d5789f7ff6 432 Hamap MF_00210 3-phosphoshikimate 1-carboxyvinyltransferase [aroA]. 11 431 31.56 T 28-03-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 CO689_RS12765 e2c8ca09f7d9edd1ddab95d5789f7ff6 432 TIGRFAM TIGR01356 aroA: 3-phosphoshikimate 1-carboxyvinyltransferase 15 429 7.4E-111 T 28-03-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 CO689_RS12765 e2c8ca09f7d9edd1ddab95d5789f7ff6 432 SUPERFAMILY SSF55205 10 428 3.66E-111 T 28-03-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 CO689_RS12765 e2c8ca09f7d9edd1ddab95d5789f7ff6 432 Gene3D G3DSA:3.65.10.10 217 431 3.0E-41 T 28-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 CO689_RS06285 e1b89572901fff99cf75b4f0cf151c77 299 Pfam PF02517 CAAX protease self-immunity 144 234 1.4E-12 T 28-03-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 CO689_RS06285 e1b89572901fff99cf75b4f0cf151c77 299 Gene3D G3DSA:1.20.1250.20 3 291 2.8E-5 T 28-03-2018 CO689_RS04845 ff7f7dfb5c01902e71619a33c80d627a 230 Gene3D G3DSA:3.40.190.10 1 230 6.0E-6 T 28-03-2018 CO689_RS01980 a8a9ab8b3ed6aa2b6ce1cc6cf8d0f41e 341 Gene3D G3DSA:3.40.640.10 1 254 2.2E-30 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CO689_RS01980 a8a9ab8b3ed6aa2b6ce1cc6cf8d0f41e 341 Gene3D G3DSA:3.90.1150.10 255 341 5.4E-16 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CO689_RS01980 a8a9ab8b3ed6aa2b6ce1cc6cf8d0f41e 341 Pfam PF01212 Beta-eliminating lyase 16 291 2.1E-30 T 28-03-2018 IPR001597 Aromatic amino acid beta-eliminating lyase/threonine aldolase GO:0006520|GO:0016829 Reactome: R-HSA-6783984 CO689_RS01980 a8a9ab8b3ed6aa2b6ce1cc6cf8d0f41e 341 SUPERFAMILY SSF53383 1 341 2.64E-76 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CO689_RS04430 a8007147269ade90834a577f52b9c45c 195 Pfam PF07563 Protein of unknown function (DUF1541) 138 189 5.0E-22 T 28-03-2018 IPR011438 Domain of unknown function DUF1541 CO689_RS04430 a8007147269ade90834a577f52b9c45c 195 Pfam PF07563 Protein of unknown function (DUF1541) 74 124 6.4E-21 T 28-03-2018 IPR011438 Domain of unknown function DUF1541 CO689_RS04430 a8007147269ade90834a577f52b9c45c 195 Gene3D G3DSA:3.40.190.10 5 184 3.1E-5 T 28-03-2018 CO689_RS10805 8ce9dc95241ebd8c359e278bb58938d1 88 SUPERFAMILY SSF55594 1 83 1.28E-28 T 28-03-2018 IPR000032 Phosphocarrier protein HPr-like CO689_RS10805 8ce9dc95241ebd8c359e278bb58938d1 88 ProSitePatterns PS00369 PTS HPR domain histidine phosphorylation site signature. 13 20 - T 28-03-2018 IPR001020 Phosphotransferase system, HPr histidine phosphorylation site CO689_RS10805 8ce9dc95241ebd8c359e278bb58938d1 88 PRINTS PR00107 Phosphocarrier protein signature 38 53 3.5E-26 T 28-03-2018 IPR000032 Phosphocarrier protein HPr-like CO689_RS10805 8ce9dc95241ebd8c359e278bb58938d1 88 PRINTS PR00107 Phosphocarrier protein signature 53 70 3.5E-26 T 28-03-2018 IPR000032 Phosphocarrier protein HPr-like CO689_RS10805 8ce9dc95241ebd8c359e278bb58938d1 88 PRINTS PR00107 Phosphocarrier protein signature 13 29 3.5E-26 T 28-03-2018 IPR000032 Phosphocarrier protein HPr-like CO689_RS10805 8ce9dc95241ebd8c359e278bb58938d1 88 Gene3D G3DSA:3.30.1340.10 1 88 6.9E-33 T 28-03-2018 IPR000032 Phosphocarrier protein HPr-like CO689_RS10805 8ce9dc95241ebd8c359e278bb58938d1 88 ProSitePatterns PS00589 PTS HPR domain serine phosphorylation site signature. 39 54 - T 28-03-2018 IPR002114 Phosphotransferase system, HPr serine phosphorylation site CO689_RS10805 8ce9dc95241ebd8c359e278bb58938d1 88 TIGRFAM TIGR01003 PTS_HPr_family: phosphocarrier, HPr family 1 81 2.5E-34 T 28-03-2018 IPR000032 Phosphocarrier protein HPr-like CO689_RS10805 8ce9dc95241ebd8c359e278bb58938d1 88 Pfam PF00381 PTS HPr component phosphorylation site 3 82 2.1E-30 T 28-03-2018 IPR000032 Phosphocarrier protein HPr-like CO689_RS02215 3baf857ef682eab1e42e487dc3b0fb7e 193 Gene3D G3DSA:3.20.19.10 1 171 2.8E-45 T 28-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel CO689_RS02215 3baf857ef682eab1e42e487dc3b0fb7e 193 Pfam PF00694 Aconitase C-terminal domain 7 126 2.7E-34 T 28-03-2018 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain GO:0008152 KEGG: 00290+4.2.1.33 CO689_RS02215 3baf857ef682eab1e42e487dc3b0fb7e 193 Hamap MF_01031 3-isopropylmalate dehydratase small subunit [leuD]. 4 193 38.986 T 28-03-2018 IPR004431 3-isopropylmalate dehydratase, small subunit GO:0003861|GO:0009098|GO:0009316 KEGG: 00290+4.2.1.33 CO689_RS02215 3baf857ef682eab1e42e487dc3b0fb7e 193 TIGRFAM TIGR00171 leuD: 3-isopropylmalate dehydratase, small subunit 5 183 1.4E-65 T 28-03-2018 IPR004431 3-isopropylmalate dehydratase, small subunit GO:0003861|GO:0009098|GO:0009316 KEGG: 00290+4.2.1.33 CO689_RS02215 3baf857ef682eab1e42e487dc3b0fb7e 193 SUPERFAMILY SSF52016 5 189 1.43E-54 T 28-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel CO689_RS04135 4a7b3864fe8907d3ef63aef14559e3fe 255 Gene3D G3DSA:3.40.50.1820 1 255 9.4E-30 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CO689_RS04135 4a7b3864fe8907d3ef63aef14559e3fe 255 SUPERFAMILY SSF53474 4 251 1.09E-41 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CO689_RS04135 4a7b3864fe8907d3ef63aef14559e3fe 255 Pfam PF00756 Putative esterase 12 244 7.5E-20 T 28-03-2018 IPR000801 Putative esterase Reactome: R-HSA-156590 CO689_RS10655 478f91555a8e1fb2f830f2ec2adca9f1 444 Pfam PF05598 Transposase domain (DUF772) 52 127 3.1E-21 T 28-03-2018 IPR008490 Transposase InsH, N-terminal CO689_RS10655 478f91555a8e1fb2f830f2ec2adca9f1 444 Pfam PF13751 Transposase DDE domain 321 439 1.9E-22 T 28-03-2018 IPR025668 Transposase DDE domain CO689_RS13555 45751c397664322c63a6fa6609f9d422 151 Hamap MF_00707 UPF0735 ACT domain-containing protein . 5 150 28.812 T 28-03-2018 IPR008310 UPF0735 ACT domain-containing protein CO689_RS13555 45751c397664322c63a6fa6609f9d422 151 SUPERFAMILY SSF55021 72 147 1.32E-10 T 28-03-2018 CO689_RS13555 45751c397664322c63a6fa6609f9d422 151 Gene3D G3DSA:3.30.70.260 69 146 1.2E-11 T 28-03-2018 CO689_RS13555 45751c397664322c63a6fa6609f9d422 151 PIRSF PIRSF025624 1 150 3.1E-59 T 28-03-2018 IPR008310 UPF0735 ACT domain-containing protein CO689_RS03755 8ae4ccb90615df4a46f2f5614a1d09ef 841 Pfam PF03176 MMPL family 514 822 1.5E-48 T 28-03-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 CO689_RS03755 8ae4ccb90615df4a46f2f5614a1d09ef 841 Pfam PF03176 MMPL family 49 356 8.3E-57 T 28-03-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 CO689_RS03755 8ae4ccb90615df4a46f2f5614a1d09ef 841 SUPERFAMILY SSF82866 588 821 4.97E-30 T 28-03-2018 CO689_RS03755 8ae4ccb90615df4a46f2f5614a1d09ef 841 SUPERFAMILY SSF82866 172 332 7.72E-32 T 28-03-2018 CO689_RS03755 8ae4ccb90615df4a46f2f5614a1d09ef 841 Gene3D G3DSA:1.20.120.570 416 588 4.0E-5 T 28-03-2018 CO689_RS03755 8ae4ccb90615df4a46f2f5614a1d09ef 841 Gene3D G3DSA:1.20.1640.10 103 329 6.4E-37 T 28-03-2018 CO689_RS03755 8ae4ccb90615df4a46f2f5614a1d09ef 841 Gene3D G3DSA:1.20.1640.10 589 817 6.4E-26 T 28-03-2018 CO689_RS04620 6f5a48d3bf4414b0fe574b50069a6834 193 Pfam PF13302 Acetyltransferase (GNAT) domain 12 157 3.2E-20 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CO689_RS04620 6f5a48d3bf4414b0fe574b50069a6834 193 Gene3D G3DSA:3.40.630.30 5 187 5.7E-28 T 28-03-2018 CO689_RS04620 6f5a48d3bf4414b0fe574b50069a6834 193 SUPERFAMILY SSF55729 7 180 2.98E-37 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CO689_RS13575 bcfb66fe14794c030e1846bbb3254feb 102 SUPERFAMILY SSF141091 1 101 6.28E-39 T 28-03-2018 IPR028909 Ribosomal protein L21-like GO:0005840 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CO689_RS13575 bcfb66fe14794c030e1846bbb3254feb 102 Hamap MF_01363 50S ribosomal protein L21 [rplU]. 1 102 26.657 T 28-03-2018 IPR001787 Ribosomal protein L21 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CO689_RS13575 bcfb66fe14794c030e1846bbb3254feb 102 TIGRFAM TIGR00061 L21: ribosomal protein bL21 2 100 2.0E-38 T 28-03-2018 IPR001787 Ribosomal protein L21 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CO689_RS13575 bcfb66fe14794c030e1846bbb3254feb 102 Pfam PF00829 Ribosomal prokaryotic L21 protein 1 100 3.9E-41 T 28-03-2018 IPR028909 Ribosomal protein L21-like GO:0005840 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CO689_RS13340 85c75631a69f493a165926de7d677d6a 153 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 70 105 - T 28-03-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 CO689_RS13340 85c75631a69f493a165926de7d677d6a 153 Gene3D G3DSA:3.40.140.10 3 149 6.4E-43 T 28-03-2018 CO689_RS13340 85c75631a69f493a165926de7d677d6a 153 SUPERFAMILY SSF53927 8 140 3.95E-43 T 28-03-2018 IPR016193 Cytidine deaminase-like GO:0003824 CO689_RS13340 85c75631a69f493a165926de7d677d6a 153 TIGRFAM TIGR02571 ComEB: ComE operon protein 2 2 148 9.4E-90 T 28-03-2018 IPR013404 Competence operon E, ComEB CO689_RS13340 85c75631a69f493a165926de7d677d6a 153 PIRSF PIRSF006019 1 149 1.7E-61 T 28-03-2018 IPR016473 Deoxycytidylate deaminase GO:0004132|GO:0006220|GO:0008270 KEGG: 00240+3.5.4.12|MetaCyc: PWY-7210|Reactome: R-HSA-499943 CO689_RS13340 85c75631a69f493a165926de7d677d6a 153 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 5 116 9.0E-31 T 28-03-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain CO689_RS08260 c427b9d8254795cd531bf02c143f6be2 208 Pfam PF09335 SNARE associated Golgi protein 30 161 3.2E-24 T 28-03-2018 IPR032816 SNARE associated Golgi protein CO689_RS09695 0370f0d65b761e6c2e9bcd2cb7e50602 54 ProDom PD053211 ACTIVATOR RINB PHAGE TRANSCRIPTIONAL ORF ORF090 GENE PHI INT ORF100 13 41 8.0E-9 T 28-03-2018 IPR009300 Transcription activator RinB GO:0006355 CO689_RS09695 0370f0d65b761e6c2e9bcd2cb7e50602 54 Pfam PF06116 Transcriptional activator RinB 3 46 4.2E-15 T 28-03-2018 IPR009300 Transcription activator RinB GO:0006355 CO689_RS13360 df4ba8a12983bf83f8f2c6811598b403 194 Gene3D G3DSA:1.10.3210.10 1 189 1.7E-22 T 28-03-2018 CO689_RS13360 df4ba8a12983bf83f8f2c6811598b403 194 Pfam PF01966 HD domain 18 130 4.0E-10 T 28-03-2018 IPR006674 HD domain CO689_RS13360 df4ba8a12983bf83f8f2c6811598b403 194 SMART SM00471 14 141 4.4E-6 T 28-03-2018 IPR003607 HD/PDEase domain CO689_RS13360 df4ba8a12983bf83f8f2c6811598b403 194 TIGRFAM TIGR00488 TIGR00488: putative HD superfamily hydrolase 11 182 2.3E-40 T 28-03-2018 IPR005249 Conserved hypothetical protein CHP00488 CO689_RS13360 df4ba8a12983bf83f8f2c6811598b403 194 SUPERFAMILY SSF109604 4 163 2.51E-26 T 28-03-2018 CO689_RS10170 814b5fa34435c7bae114347442c533f6 355 Gene3D G3DSA:1.10.3720.10 63 355 4.4E-45 T 28-03-2018 CO689_RS10170 814b5fa34435c7bae114347442c533f6 355 SUPERFAMILY SSF161098 146 336 1.7E-27 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CO689_RS10170 814b5fa34435c7bae114347442c533f6 355 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 49 100 2.9E-17 T 28-03-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain CO689_RS10170 814b5fa34435c7bae114347442c533f6 355 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 171 355 1.6E-29 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CO689_RS04615 b9fee371de5a6fddb5d56407f68360ce 202 Gene3D G3DSA:3.60.21.10 1 198 8.0E-35 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CO689_RS04615 b9fee371de5a6fddb5d56407f68360ce 202 SUPERFAMILY SSF56300 2 173 1.14E-31 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CO689_RS04615 b9fee371de5a6fddb5d56407f68360ce 202 Pfam PF00149 Calcineurin-like phosphoesterase 4 152 5.7E-16 T 28-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 CO689_RS13390 e0efaaa76f80ca97d1d5668716480838 228 SUPERFAMILY SSF53167 2 227 1.44E-69 T 28-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 CO689_RS13390 e0efaaa76f80ca97d1d5668716480838 228 Hamap MF_01684 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase [mtnN]. 1 228 43.455 T 28-03-2018 IPR010049 MTA/SAH nucleosidase GO:0008782|GO:0008930|GO:0009164|GO:0019509 KEGG: 00270+3.2.2.9|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 CO689_RS13390 e0efaaa76f80ca97d1d5668716480838 228 TIGRFAM TIGR01704 MTA/SAH-Nsdase: MTA/SAH nucleosidase 2 227 4.4E-80 T 28-03-2018 IPR010049 MTA/SAH nucleosidase GO:0008782|GO:0008930|GO:0009164|GO:0019509 KEGG: 00270+3.2.2.9|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 CO689_RS13390 e0efaaa76f80ca97d1d5668716480838 228 Gene3D G3DSA:3.40.50.1580 1 228 8.0E-53 T 28-03-2018 CO689_RS13390 e0efaaa76f80ca97d1d5668716480838 228 Pfam PF01048 Phosphorylase superfamily 2 225 6.5E-48 T 28-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 CO689_RS02420 eb560b8f4f864a6396c850638f69867b 145 TIGRFAM TIGR01750 fabZ: beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ 6 142 3.5E-53 T 28-03-2018 IPR010084 Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ GO:0005737|GO:0006633|GO:0016836 KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 CO689_RS02420 eb560b8f4f864a6396c850638f69867b 145 Gene3D G3DSA:3.10.129.10 1 144 8.9E-54 T 28-03-2018 CO689_RS02420 eb560b8f4f864a6396c850638f69867b 145 Hamap MF_00406 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ [fabZ]. 5 144 32.093 T 28-03-2018 IPR010084 Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ GO:0005737|GO:0006633|GO:0016836 KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 CO689_RS02420 eb560b8f4f864a6396c850638f69867b 145 Pfam PF07977 FabA-like domain 14 135 2.3E-33 T 28-03-2018 IPR013114 Beta-hydroxydecanoyl thiol ester dehydrase, FabA/FabZ KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 CO689_RS02420 eb560b8f4f864a6396c850638f69867b 145 SUPERFAMILY SSF54637 3 142 1.79E-46 T 28-03-2018 IPR029069 HotDog domain CO689_RS11555 326005f68fe3e2c99599b615fce10586 110 Pfam PF04297 Putative helix-turn-helix protein, YlxM / p13 like 7 104 3.5E-40 T 28-03-2018 IPR007394 Putative helix-turn-helix protein, YlxM/p13-like CO689_RS11555 326005f68fe3e2c99599b615fce10586 110 Hamap MF_00245 UPF0122 protein . 6 107 21.646 T 28-03-2018 IPR007394 Putative helix-turn-helix protein, YlxM/p13-like CO689_RS11555 326005f68fe3e2c99599b615fce10586 110 Gene3D G3DSA:1.10.10.10 1 110 4.1E-31 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS11555 326005f68fe3e2c99599b615fce10586 110 SUPERFAMILY SSF88659 5 107 1.64E-32 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CO689_RS13430 59dc5071addf974c91c9d60f994fc31c 87 Pfam PF06135 Bacterial protein of unknown function (DUF965) 5 82 7.7E-37 T 28-03-2018 IPR009309 Uncharacterised protein family UPF0297 CO689_RS13430 59dc5071addf974c91c9d60f994fc31c 87 PIRSF PIRSF037258 1 87 5.4E-43 T 28-03-2018 IPR009309 Uncharacterised protein family UPF0297 CO689_RS13430 59dc5071addf974c91c9d60f994fc31c 87 Hamap MF_01507 UPF0297 protein . 1 84 26.995 T 28-03-2018 IPR009309 Uncharacterised protein family UPF0297 CO689_RS04905 c13ae57cb8102c522b027a1ddd856e17 223 SUPERFAMILY SSF51206 31 147 2.09E-21 T 28-03-2018 IPR018490 Cyclic nucleotide-binding-like CO689_RS04905 c13ae57cb8102c522b027a1ddd856e17 223 Pfam PF00027 Cyclic nucleotide-binding domain 36 122 2.6E-12 T 28-03-2018 IPR000595 Cyclic nucleotide-binding domain CO689_RS04905 c13ae57cb8102c522b027a1ddd856e17 223 Gene3D G3DSA:2.60.120.10 10 148 6.0E-14 T 28-03-2018 IPR014710 RmlC-like jelly roll fold CO689_RS04905 c13ae57cb8102c522b027a1ddd856e17 223 SUPERFAMILY SSF46785 151 219 8.65E-9 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS04905 c13ae57cb8102c522b027a1ddd856e17 223 Gene3D G3DSA:1.10.10.10 149 222 5.3E-8 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS08500 3ad2f0e87cde0fe6fcab2e70b7c9b81c 132 TIGRFAM TIGR01518 g3p_cytidyltrns: glycerol-3-phosphate cytidylyltransferase 4 126 3.5E-58 T 28-03-2018 IPR006409 Glycerol-3-phosphate cytidylyltransferase GO:0005737|GO:0019350|GO:0046872|GO:0047348 CO689_RS08500 3ad2f0e87cde0fe6fcab2e70b7c9b81c 132 Pfam PF01467 Cytidylyltransferase-like 5 124 1.2E-22 T 28-03-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 CO689_RS08500 3ad2f0e87cde0fe6fcab2e70b7c9b81c 132 SUPERFAMILY SSF52374 2 125 2.82E-33 T 28-03-2018 CO689_RS08500 3ad2f0e87cde0fe6fcab2e70b7c9b81c 132 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 3 67 3.9E-22 T 28-03-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 CO689_RS08500 3ad2f0e87cde0fe6fcab2e70b7c9b81c 132 Gene3D G3DSA:3.40.50.620 1 127 1.5E-29 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CO689_RS12370 2a8f1372a215a7932f556f77c3720b33 173 Pfam PF03729 Short repeat of unknown function (DUF308) 12 84 1.1E-11 T 28-03-2018 IPR005325 Protein of unknown function DUF308, membrane CO689_RS12370 2a8f1372a215a7932f556f77c3720b33 173 Pfam PF03729 Short repeat of unknown function (DUF308) 70 142 6.5E-9 T 28-03-2018 IPR005325 Protein of unknown function DUF308, membrane CO689_RS12370 2a8f1372a215a7932f556f77c3720b33 173 Pfam PF03729 Short repeat of unknown function (DUF308) 131 172 9.0E-4 T 28-03-2018 IPR005325 Protein of unknown function DUF308, membrane CO689_RS08555 433f278bd6b43639ea1b83c357668886 168 SUPERFAMILY SSF55729 2 167 1.31E-31 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CO689_RS08555 433f278bd6b43639ea1b83c357668886 168 Pfam PF13420 Acetyltransferase (GNAT) domain 5 160 1.9E-15 T 28-03-2018 CO689_RS08555 433f278bd6b43639ea1b83c357668886 168 Gene3D G3DSA:3.40.630.30 1 168 2.2E-29 T 28-03-2018 CO689_RS04750 04d5edfa304399a1177f3c6441534945 404 Pfam PF07690 Major Facilitator Superfamily 34 357 4.6E-25 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CO689_RS04750 04d5edfa304399a1177f3c6441534945 404 SUPERFAMILY SSF103473 9 393 5.75E-46 T 28-03-2018 IPR020846 Major facilitator superfamily domain CO689_RS04750 04d5edfa304399a1177f3c6441534945 404 Gene3D G3DSA:1.20.1250.20 201 395 1.3E-21 T 28-03-2018 CO689_RS04750 04d5edfa304399a1177f3c6441534945 404 Gene3D G3DSA:1.20.1250.20 11 200 6.3E-15 T 28-03-2018 CO689_RS03440 0e85ba75667f481368b24588658b758f 118 Gene3D G3DSA:1.10.10.10 5 118 2.5E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS03440 0e85ba75667f481368b24588658b758f 118 TIGRFAM TIGR01889 Staph_reg_Sar: staphylococcal accessory regulator family 12 116 4.3E-25 T 28-03-2018 IPR010166 Transcriptional regulator SarA/Rot GO:0006355 CO689_RS03440 0e85ba75667f481368b24588658b758f 118 Pfam PF12802 MarR family 33 93 5.8E-7 T 28-03-2018 CO689_RS03440 0e85ba75667f481368b24588658b758f 118 SUPERFAMILY SSF46785 8 116 2.06E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS06700 0bd20acc3b8abb042ef04c11db9c2037 223 Pfam PF00069 Protein kinase domain 7 198 2.2E-26 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CO689_RS06700 0bd20acc3b8abb042ef04c11db9c2037 223 ProSitePatterns PS00109 Tyrosine protein kinases specific active-site signature. 99 111 - T 28-03-2018 IPR008266 Tyrosine-protein kinase, active site GO:0004672|GO:0006468 CO689_RS06700 0bd20acc3b8abb042ef04c11db9c2037 223 Gene3D G3DSA:3.30.200.20 2 68 1.8E-9 T 28-03-2018 CO689_RS06700 0bd20acc3b8abb042ef04c11db9c2037 223 Gene3D G3DSA:1.10.510.10 69 223 3.2E-23 T 28-03-2018 CO689_RS06700 0bd20acc3b8abb042ef04c11db9c2037 223 SUPERFAMILY SSF56112 4 196 4.71E-37 T 28-03-2018 IPR011009 Protein kinase-like domain CO689_RS08155 189a4ec3b36da9121b3dbc1597f3b4b0 205 SUPERFAMILY SSF52540 1 200 5.12E-45 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CO689_RS08155 189a4ec3b36da9121b3dbc1597f3b4b0 205 PIRSF PIRSF000705 1 205 1.7E-58 T 28-03-2018 IPR002624 Deoxynucleoside kinase GO:0005524|GO:0006139|GO:0019206 CO689_RS08155 189a4ec3b36da9121b3dbc1597f3b4b0 205 Pfam PF01712 Deoxynucleoside kinase 6 199 4.7E-46 T 28-03-2018 IPR031314 Deoxynucleoside kinase domain CO689_RS08155 189a4ec3b36da9121b3dbc1597f3b4b0 205 Gene3D G3DSA:3.40.50.300 1 194 1.5E-37 T 28-03-2018 CO689_RS01105 fd1787379699198ff09558687a41e5b1 331 Pfam PF01619 Proline dehydrogenase 43 294 3.0E-30 T 28-03-2018 IPR002872 Proline dehydrogenase domain KEGG: 00330+1.5.5.2|MetaCyc: PWY-5737|MetaCyc: PWY-6922|Reactome: R-HSA-70688 CO689_RS01105 fd1787379699198ff09558687a41e5b1 331 Gene3D G3DSA:3.20.20.220 8 309 1.2E-56 T 28-03-2018 IPR029041 FAD-linked oxidoreductase-like CO689_RS01105 fd1787379699198ff09558687a41e5b1 331 PIRSF PIRSF000196 1 305 1.5E-117 T 28-03-2018 IPR008219 Proline dehydrogenase, bacteria and archaea GO:0004657|GO:0010133 KEGG: 00330+1.5.5.2|MetaCyc: PWY-5737|MetaCyc: PWY-6922 CO689_RS01105 fd1787379699198ff09558687a41e5b1 331 SUPERFAMILY SSF51730 36 301 2.39E-64 T 28-03-2018 IPR029041 FAD-linked oxidoreductase-like CO689_RS04745 e9eabaad833863e8370c445378a3214b 125 SUPERFAMILY SSF159888 1 122 4.58E-40 T 28-03-2018 CO689_RS04745 e9eabaad833863e8370c445378a3214b 125 Pfam PF08818 Domain of unknown function (DU1801) 17 109 6.1E-14 T 28-03-2018 IPR014922 Domain of unknown function DUF1801 CO689_RS09620 4c6f1aa51d18360b19f12aa535a35c9f 225 Pfam PF16784 Putative HNHc nuclease 22 221 1.1E-67 T 28-03-2018 IPR031879 Fanconi anemia group M protein, MHF binding domain Reactome: R-HSA-6783310 CO689_RS02360 49cefe3acbb9ef48244c5e45c1387b23 493 Pfam PF13396 Phospholipase_D-nuclease N-terminal 24 67 3.6E-10 T 28-03-2018 IPR027379 Cardiolipin synthase N-terminal CO689_RS02360 49cefe3acbb9ef48244c5e45c1387b23 493 SUPERFAMILY SSF56024 280 480 1.37E-50 T 28-03-2018 CO689_RS02360 49cefe3acbb9ef48244c5e45c1387b23 493 Pfam PF13091 PLD-like domain 145 273 2.6E-13 T 28-03-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 CO689_RS02360 49cefe3acbb9ef48244c5e45c1387b23 493 Pfam PF13091 PLD-like domain 335 460 1.3E-30 T 28-03-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 CO689_RS02360 49cefe3acbb9ef48244c5e45c1387b23 493 SUPERFAMILY SSF56024 90 326 2.62E-53 T 28-03-2018 CO689_RS02360 49cefe3acbb9ef48244c5e45c1387b23 493 SMART SM00155 228 255 2.8E-5 T 28-03-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 CO689_RS02360 49cefe3acbb9ef48244c5e45c1387b23 493 SMART SM00155 406 433 5.0E-8 T 28-03-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 CO689_RS02360 49cefe3acbb9ef48244c5e45c1387b23 493 Gene3D G3DSA:3.30.870.10 323 487 1.7E-33 T 28-03-2018 CO689_RS02360 49cefe3acbb9ef48244c5e45c1387b23 493 Hamap MF_01916 Cardiolipin synthase. 20 493 43.116 T 28-03-2018 IPR030874 Cardiolipin synthase, Firmicutes-type GO:0008808|GO:0032049 CO689_RS02360 49cefe3acbb9ef48244c5e45c1387b23 493 Gene3D G3DSA:3.30.870.10 119 320 1.4E-34 T 28-03-2018 CO689_RS02360 49cefe3acbb9ef48244c5e45c1387b23 493 TIGRFAM TIGR04265 bac_cardiolipin: cardiolipin synthase 14 493 7.8E-221 T 28-03-2018 IPR022924 Cardiolipin synthase GO:0008808|GO:0016780|GO:0032049 CO689_RS13275 edd9666bb5d02197589f136531470243 58 PRINTS PR00976 Ribosomal protein S21 family signature 37 47 5.3E-16 T 28-03-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CO689_RS13275 edd9666bb5d02197589f136531470243 58 PRINTS PR00976 Ribosomal protein S21 family signature 13 22 5.3E-16 T 28-03-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CO689_RS13275 edd9666bb5d02197589f136531470243 58 PRINTS PR00976 Ribosomal protein S21 family signature 25 35 5.3E-16 T 28-03-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CO689_RS13275 edd9666bb5d02197589f136531470243 58 PRINTS PR00976 Ribosomal protein S21 family signature 5 13 5.3E-16 T 28-03-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CO689_RS13275 edd9666bb5d02197589f136531470243 58 Gene3D G3DSA:1.20.5.1150 16 52 7.1E-19 T 28-03-2018 CO689_RS13275 edd9666bb5d02197589f136531470243 58 Pfam PF01165 Ribosomal protein S21 5 57 5.9E-22 T 28-03-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CO689_RS13275 edd9666bb5d02197589f136531470243 58 TIGRFAM TIGR00030 S21p: ribosomal protein bS21 3 58 1.1E-21 T 28-03-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CO689_RS13275 edd9666bb5d02197589f136531470243 58 ProSitePatterns PS01181 Ribosomal protein S21 signature. 13 25 - T 28-03-2018 IPR018278 Ribosomal protein S21, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CO689_RS13275 edd9666bb5d02197589f136531470243 58 ProDom PD005521 RIBOSOMAL S21 RIBONUCLEOPROTEIN 30S S21P A SSU SUBUNIT SEQUENCING DIRECT 16 43 1.0E-8 T 28-03-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CO689_RS13275 edd9666bb5d02197589f136531470243 58 Hamap MF_00358 30S ribosomal protein S21 [rpsU]. 1 57 21.847 T 28-03-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CO689_RS12625 f2dfc99854b92d6c901a4bc66176888d 144 TIGRFAM TIGR04191 YphP_YqiW: putative bacilliredoxin, YphP/YqiW family 7 144 2.5E-58 T 28-03-2018 IPR009474 Putative bacilliredoxin, YphP/YqiW family CO689_RS12625 f2dfc99854b92d6c901a4bc66176888d 144 Pfam PF06491 Disulphide isomerase 7 144 1.2E-55 T 28-03-2018 IPR009474 Putative bacilliredoxin, YphP/YqiW family CO689_RS07570 1c0e3841d7b50e9a1dc08b97093dc5f2 109 Pfam PF06153 Cyclic-di-AMP receptor 1 109 2.7E-54 T 28-03-2018 IPR010375 Cyclic-di-AMP receptor CO689_RS07570 1c0e3841d7b50e9a1dc08b97093dc5f2 109 SUPERFAMILY SSF54913 1 108 1.56E-13 T 28-03-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta CO689_RS07570 1c0e3841d7b50e9a1dc08b97093dc5f2 109 Gene3D G3DSA:3.30.70.120 1 109 2.4E-15 T 28-03-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal CO689_RS12995 c95d5153ba0501d67580b67ef7cd40b9 150 Hamap MF_00173 Arginine repressor [argR]. 1 150 65.818 T 28-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 CO689_RS12995 c95d5153ba0501d67580b67ef7cd40b9 150 SUPERFAMILY SSF55252 80 150 6.15E-22 T 28-03-2018 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 CO689_RS12995 c95d5153ba0501d67580b67ef7cd40b9 150 Gene3D G3DSA:3.30.1360.40 75 146 2.0E-27 T 28-03-2018 IPR024946 Arginine repressor C-terminal-like domain Reactome: R-HSA-4615885 CO689_RS12995 c95d5153ba0501d67580b67ef7cd40b9 150 PRINTS PR01467 Bacterial arginine repressor signature 38 53 3.0E-23 T 28-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 CO689_RS12995 c95d5153ba0501d67580b67ef7cd40b9 150 PRINTS PR01467 Bacterial arginine repressor signature 89 102 3.0E-23 T 28-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 CO689_RS12995 c95d5153ba0501d67580b67ef7cd40b9 150 PRINTS PR01467 Bacterial arginine repressor signature 22 35 3.0E-23 T 28-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 CO689_RS12995 c95d5153ba0501d67580b67ef7cd40b9 150 PRINTS PR01467 Bacterial arginine repressor signature 119 134 3.0E-23 T 28-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 CO689_RS12995 c95d5153ba0501d67580b67ef7cd40b9 150 Gene3D G3DSA:1.10.10.10 4 67 2.2E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS12995 c95d5153ba0501d67580b67ef7cd40b9 150 TIGRFAM TIGR01529 argR_whole: arginine repressor 7 150 1.4E-48 T 28-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 CO689_RS12995 c95d5153ba0501d67580b67ef7cd40b9 150 Pfam PF02863 Arginine repressor, C-terminal domain 82 146 2.8E-25 T 28-03-2018 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 CO689_RS12995 c95d5153ba0501d67580b67ef7cd40b9 150 SUPERFAMILY SSF46785 2 71 6.07E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS12995 c95d5153ba0501d67580b67ef7cd40b9 150 ProDom PD007402 ARGININE REPRESSOR TRANSCRIPTION BIOSYNTHESIS DNA-BINDING REGULATION AMINO-ACID ARGR TRANSCRIPTIONAL FAMILY 88 150 5.0E-17 T 28-03-2018 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 CO689_RS12995 c95d5153ba0501d67580b67ef7cd40b9 150 Pfam PF01316 Arginine repressor, DNA binding domain 2 70 2.0E-25 T 28-03-2018 IPR020900 Arginine repressor, DNA-binding domain GO:0003700|GO:0006355|GO:0006525 CO689_RS12855 616837d1b7792dd0f0901772632d2c68 182 PIRSF PIRSF037778 2 182 1.3E-48 T 28-03-2018 IPR025720 ECF transporter, Riboflavin transporter RibU GO:0005886|GO:0032217|GO:0032218 CO689_RS12855 616837d1b7792dd0f0901772632d2c68 182 Pfam PF12822 ECF transporter, substrate-specific component 7 173 5.2E-26 T 28-03-2018 IPR024529 ECF transporter, substrate-specific component GO:0005215 CO689_RS04580 31e52d329cbc9d231453504ff5a9f8bc 288 Pfam PF00483 Nucleotidyl transferase 6 258 2.3E-35 T 28-03-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 CO689_RS04580 31e52d329cbc9d231453504ff5a9f8bc 288 TIGRFAM TIGR01099 galU: UTP--glucose-1-phosphate uridylyltransferase 4 264 1.0E-120 T 28-03-2018 IPR005771 UTP--glucose-1-phosphate uridylyltransferase, bacterial/archaeal-type GO:0003983|GO:0006011 KEGG: 00040+2.7.7.9|KEGG: 00052+2.7.7.9|KEGG: 00500+2.7.7.9|KEGG: 00520+2.7.7.9|MetaCyc: PWY-3801|MetaCyc: PWY-6527|MetaCyc: PWY-7238|MetaCyc: PWY-7343|MetaCyc: PWY-7817 CO689_RS04580 31e52d329cbc9d231453504ff5a9f8bc 288 Gene3D G3DSA:3.90.550.10 2 277 1.4E-62 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CO689_RS04580 31e52d329cbc9d231453504ff5a9f8bc 288 SUPERFAMILY SSF53448 2 268 2.21E-70 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CO689_RS04855 6e6a75e44dda63bf3829fd5532f7b5c1 384 Pfam PF01979 Amidohydrolase family 51 381 1.8E-27 T 28-03-2018 IPR006680 Amidohydrolase-related GO:0016787 CO689_RS04855 6e6a75e44dda63bf3829fd5532f7b5c1 384 Gene3D G3DSA:2.30.40.10 1 68 3.9E-19 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CO689_RS04855 6e6a75e44dda63bf3829fd5532f7b5c1 384 TIGRFAM TIGR00221 nagA: N-acetylglucosamine-6-phosphate deacetylase 3 379 5.5E-117 T 28-03-2018 IPR003764 N-acetylglucosamine-6-phosphate deacetylase GO:0006044|GO:0008448 KEGG: 00052+3.5.1.25|KEGG: 00520+3.5.1.25|MetaCyc: PWY-6906|MetaCyc: PWY-7077|MetaCyc: PWY-7395|Reactome: R-HSA-446210 CO689_RS04855 6e6a75e44dda63bf3829fd5532f7b5c1 384 SUPERFAMILY SSF51556 55 353 3.04E-95 T 28-03-2018 IPR032466 Metal-dependent hydrolase CO689_RS04855 6e6a75e44dda63bf3829fd5532f7b5c1 384 SUPERFAMILY SSF51338 4 54 1.1E-20 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CO689_RS04855 6e6a75e44dda63bf3829fd5532f7b5c1 384 SUPERFAMILY SSF51338 353 382 1.1E-20 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CO689_RS04855 6e6a75e44dda63bf3829fd5532f7b5c1 384 PIRSF PIRSF038994 2 383 4.1E-131 T 28-03-2018 IPR003764 N-acetylglucosamine-6-phosphate deacetylase GO:0006044|GO:0008448 KEGG: 00052+3.5.1.25|KEGG: 00520+3.5.1.25|MetaCyc: PWY-6906|MetaCyc: PWY-7077|MetaCyc: PWY-7395|Reactome: R-HSA-446210 CO689_RS04855 6e6a75e44dda63bf3829fd5532f7b5c1 384 Gene3D G3DSA:3.20.20.140 69 353 3.1E-107 T 28-03-2018 CO689_RS03280 3bdc5182341567a99545d863b04a9d56 200 Hamap MF_00316 Molybdenum cofactor guanylyltransferase [mobA]. 1 195 22.241 T 28-03-2018 IPR013482 Molybdenum cofactor guanylyltransferase GO:0003824|GO:0006777 KEGG: 00790+2.7.7.77|MetaCyc: PWY-5964|MetaCyc: PWY-7639 CO689_RS03280 3bdc5182341567a99545d863b04a9d56 200 SUPERFAMILY SSF53448 2 195 8.97E-26 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CO689_RS03280 3bdc5182341567a99545d863b04a9d56 200 Pfam PF12804 MobA-like NTP transferase domain 3 164 1.5E-28 T 28-03-2018 IPR025877 MobA-like NTP transferase CO689_RS03280 3bdc5182341567a99545d863b04a9d56 200 Gene3D G3DSA:3.90.550.10 1 198 2.4E-32 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CO689_RS04370 614325012db03da5f8a2298f56345ca5 347 Pfam PF13303 Phosphotransferase system, EIIC 31 331 4.9E-45 T 28-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 CO689_RS01900 b7e44927ad2d0697d47c13e55b00745d 113 Pfam PF08863 YolD-like protein 13 106 1.5E-23 T 28-03-2018 IPR014962 YolD-like protein CO689_RS05860 eb102e99443662095a827b740d780eb2 434 PIRSF PIRSF000337 4 434 6.1E-134 T 28-03-2018 IPR016215 Nitrilotriacetate monooxygenase component A/pristinamycin IIA synthase subunit A GO:0004497 CO689_RS05860 eb102e99443662095a827b740d780eb2 434 SUPERFAMILY SSF51679 7 433 5.54E-113 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CO689_RS05860 eb102e99443662095a827b740d780eb2 434 TIGRFAM TIGR03860 FMN_nitrolo: FMN-dependent oxidoreductase, nitrilotriacetate monooxygenase family 12 431 1.7E-144 T 28-03-2018 IPR016215 Nitrilotriacetate monooxygenase component A/pristinamycin IIA synthase subunit A GO:0004497 CO689_RS05860 eb102e99443662095a827b740d780eb2 434 Gene3D G3DSA:3.20.20.30 1 434 7.4E-92 T 28-03-2018 CO689_RS05860 eb102e99443662095a827b740d780eb2 434 Pfam PF00296 Luciferase-like monooxygenase 23 387 3.3E-53 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CO689_RS04605 3984ee9e886379d3f1d76a9d22bf22c2 59 Pfam PF12669 Virus attachment protein p12 family 6 43 8.6E-10 T 28-03-2018 CO689_RS04505 a83f61f675e9558cd432113f6e0c090e 476 Gene3D G3DSA:3.40.50.300 233 472 4.3E-87 T 28-03-2018 CO689_RS04505 a83f61f675e9558cd432113f6e0c090e 476 Gene3D G3DSA:3.40.50.300 1 230 3.9E-42 T 28-03-2018 CO689_RS04505 a83f61f675e9558cd432113f6e0c090e 476 Pfam PF03976 Polyphosphate kinase 2 (PPK2) 4 216 1.1E-27 T 28-03-2018 IPR022488 Polyphosphate kinase-2-related CO689_RS04505 a83f61f675e9558cd432113f6e0c090e 476 Pfam PF03976 Polyphosphate kinase 2 (PPK2) 247 467 5.0E-85 T 28-03-2018 IPR022488 Polyphosphate kinase-2-related CO689_RS04505 a83f61f675e9558cd432113f6e0c090e 476 SUPERFAMILY SSF52540 276 466 2.3E-28 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CO689_RS04505 a83f61f675e9558cd432113f6e0c090e 476 SUPERFAMILY SSF52540 25 217 1.28E-10 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CO689_RS04040 c31717761a27a675bb8cb2562f45bcf1 244 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 47 235 4.7E-26 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CO689_RS04040 c31717761a27a675bb8cb2562f45bcf1 244 SUPERFAMILY SSF161098 28 230 1.06E-46 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CO689_RS04040 c31717761a27a675bb8cb2562f45bcf1 244 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 31 133 5.5E-25 T 28-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 CO689_RS04040 c31717761a27a675bb8cb2562f45bcf1 244 Gene3D G3DSA:1.10.3720.10 4 244 2.3E-44 T 28-03-2018 CO689_RS11645 4ea3c571442c7c8ba40a1d1da2daacc9 688 Gene3D G3DSA:2.70.20.10 326 453 6.0E-38 T 28-03-2018 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 CO689_RS11645 4ea3c571442c7c8ba40a1d1da2daacc9 688 Pfam PF01751 Toprim domain 5 113 9.6E-31 T 28-03-2018 IPR006171 TOPRIM domain CO689_RS11645 4ea3c571442c7c8ba40a1d1da2daacc9 688 TIGRFAM TIGR01051 topA_bact: DNA topoisomerase I 5 608 1.4E-256 T 28-03-2018 IPR005733 DNA topoisomerase I, bacterial-type GO:0003677|GO:0003917|GO:0006265 CO689_RS11645 4ea3c571442c7c8ba40a1d1da2daacc9 688 SMART SM00437 242 507 3.7E-118 T 28-03-2018 IPR003602 DNA topoisomerase, type IA, DNA-binding domain GO:0003677|GO:0003916|GO:0006265 CO689_RS11645 4ea3c571442c7c8ba40a1d1da2daacc9 688 SUPERFAMILY SSF57783 573 610 2.21E-14 T 28-03-2018 CO689_RS11645 4ea3c571442c7c8ba40a1d1da2daacc9 688 SMART SM00436 104 192 7.4E-49 T 28-03-2018 IPR003601 DNA topoisomerase, type IA, domain 2 GO:0003677|GO:0003916|GO:0006265 CO689_RS11645 4ea3c571442c7c8ba40a1d1da2daacc9 688 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 162 180 8.9E-36 T 28-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CO689_RS11645 4ea3c571442c7c8ba40a1d1da2daacc9 688 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 368 384 8.9E-36 T 28-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CO689_RS11645 4ea3c571442c7c8ba40a1d1da2daacc9 688 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 470 484 8.9E-36 T 28-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CO689_RS11645 4ea3c571442c7c8ba40a1d1da2daacc9 688 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 293 302 8.9E-36 T 28-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CO689_RS11645 4ea3c571442c7c8ba40a1d1da2daacc9 688 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 77 90 8.9E-36 T 28-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CO689_RS11645 4ea3c571442c7c8ba40a1d1da2daacc9 688 ProSitePatterns PS00396 Prokaryotic DNA topoisomerase I active site. 279 302 - T 28-03-2018 IPR023406 DNA topoisomerase, type IA, active site GO:0003917 CO689_RS11645 4ea3c571442c7c8ba40a1d1da2daacc9 688 Hamap MF_00952 DNA topoisomerase 1 [topA]. 3 630 55.461 T 28-03-2018 IPR028612 DNA topoisomerase I, type IA GO:0003677|GO:0003916|GO:0006265 CO689_RS11645 4ea3c571442c7c8ba40a1d1da2daacc9 688 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 613 652 1.3E-15 T 28-03-2018 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 CO689_RS11645 4ea3c571442c7c8ba40a1d1da2daacc9 688 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 654 687 0.0039 T 28-03-2018 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 CO689_RS11645 4ea3c571442c7c8ba40a1d1da2daacc9 688 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 573 609 7.9E-17 T 28-03-2018 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 CO689_RS11645 4ea3c571442c7c8ba40a1d1da2daacc9 688 Pfam PF01131 DNA topoisomerase 128 544 1.1E-134 T 28-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CO689_RS11645 4ea3c571442c7c8ba40a1d1da2daacc9 688 Gene3D G3DSA:1.10.460.10 135 325 4.9E-47 T 28-03-2018 CO689_RS11645 4ea3c571442c7c8ba40a1d1da2daacc9 688 Gene3D G3DSA:3.30.65.10 554 610 2.4E-18 T 28-03-2018 CO689_RS11645 4ea3c571442c7c8ba40a1d1da2daacc9 688 Gene3D G3DSA:3.30.65.10 650 688 6.4E-5 T 28-03-2018 CO689_RS11645 4ea3c571442c7c8ba40a1d1da2daacc9 688 Gene3D G3DSA:3.30.65.10 611 649 2.3E-12 T 28-03-2018 CO689_RS11645 4ea3c571442c7c8ba40a1d1da2daacc9 688 SMART SM00493 3 103 2.9E-36 T 28-03-2018 IPR006171 TOPRIM domain CO689_RS11645 4ea3c571442c7c8ba40a1d1da2daacc9 688 SUPERFAMILY SSF56712 4 586 2.49E-199 T 28-03-2018 IPR023405 DNA topoisomerase, type IA, core domain CO689_RS11645 4ea3c571442c7c8ba40a1d1da2daacc9 688 Gene3D G3DSA:3.40.50.140 2 129 4.2E-39 T 28-03-2018 CO689_RS05235 ebbfcc93e93888bd9912e4aa441c05c3 226 SUPERFAMILY SSF52317 1 226 2.89E-66 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CO689_RS05235 ebbfcc93e93888bd9912e4aa441c05c3 226 Pfam PF01965 DJ-1/PfpI family 28 222 3.1E-12 T 28-03-2018 IPR002818 DJ-1/PfpI CO689_RS05235 ebbfcc93e93888bd9912e4aa441c05c3 226 Gene3D G3DSA:3.40.50.880 1 226 4.1E-48 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CO689_RS00405 25016b9b9ba4095a03cbff6792291799 189 Pfam PF14278 Transcriptional regulator C-terminal region 82 162 1.2E-6 T 28-03-2018 CO689_RS00405 25016b9b9ba4095a03cbff6792291799 189 Gene3D G3DSA:1.10.10.60 3 46 2.1E-9 T 28-03-2018 CO689_RS00405 25016b9b9ba4095a03cbff6792291799 189 Gene3D G3DSA:1.10.10.60 47 176 5.9E-6 T 28-03-2018 CO689_RS00405 25016b9b9ba4095a03cbff6792291799 189 SUPERFAMILY SSF46689 6 68 9.93E-14 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CO689_RS00405 25016b9b9ba4095a03cbff6792291799 189 Pfam PF00440 Bacterial regulatory proteins, tetR family 23 56 1.7E-6 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CO689_RS04700 f8efe936ea358a77a0c2be34a4341d94 448 Gene3D G3DSA:3.40.190.10 46 142 0.0017 T 28-03-2018 CO689_RS04700 f8efe936ea358a77a0c2be34a4341d94 448 Pfam PF03929 PepSY-associated TM region 11 387 8.2E-51 T 28-03-2018 IPR005625 PepSY-associated TM protein CO689_RS13425 61c4e5dbc8fc07e99b1a980e292ba050 141 Hamap MF_00651 Putative pre-16S rRNA nuclease [yqgF]. 4 141 22.773 T 28-03-2018 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 CO689_RS13425 61c4e5dbc8fc07e99b1a980e292ba050 141 Pfam PF03652 Holliday junction resolvase 5 140 2.0E-41 T 28-03-2018 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 CO689_RS13425 61c4e5dbc8fc07e99b1a980e292ba050 141 SMART SM00732 4 107 2.7E-30 T 28-03-2018 IPR006641 YqgF/RNase H-like domain GO:0006139 CO689_RS13425 61c4e5dbc8fc07e99b1a980e292ba050 141 Gene3D G3DSA:3.30.420.140 2 141 4.6E-41 T 28-03-2018 IPR006641 YqgF/RNase H-like domain GO:0006139 CO689_RS13425 61c4e5dbc8fc07e99b1a980e292ba050 141 TIGRFAM TIGR00250 RNAse_H_YqgF: putative transcription antitermination factor YqgF 7 139 2.2E-39 T 28-03-2018 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 CO689_RS13425 61c4e5dbc8fc07e99b1a980e292ba050 141 SUPERFAMILY SSF53098 5 140 4.7E-41 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CO689_RS13230 afe9a8e051f882e95db4821675bb3aea 255 TIGRFAM TIGR00613 reco: DNA repair protein RecO 4 245 1.1E-58 T 28-03-2018 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 CO689_RS13230 afe9a8e051f882e95db4821675bb3aea 255 Pfam PF11967 Recombination protein O N terminal 1 77 2.1E-16 T 28-03-2018 IPR022572 DNA replication/recombination mediator RecO, N-terminal CO689_RS13230 afe9a8e051f882e95db4821675bb3aea 255 Pfam PF02565 Recombination protein O C terminal 82 238 9.5E-21 T 28-03-2018 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 CO689_RS13230 afe9a8e051f882e95db4821675bb3aea 255 SUPERFAMILY SSF57863 81 233 5.49E-24 T 28-03-2018 CO689_RS13230 afe9a8e051f882e95db4821675bb3aea 255 Hamap MF_00201 DNA repair protein RecO [recO]. 1 245 19.947 T 28-03-2018 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 CO689_RS13230 afe9a8e051f882e95db4821675bb3aea 255 Gene3D G3DSA:2.40.50.140 1 81 5.5E-17 T 28-03-2018 CO689_RS13230 afe9a8e051f882e95db4821675bb3aea 255 SUPERFAMILY SSF50249 1 76 3.6E-11 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CO689_RS07370 36929b32d485e66162e3a27edb40a9db 329 Gene3D G3DSA:3.10.180.10 161 321 3.3E-22 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CO689_RS07370 36929b32d485e66162e3a27edb40a9db 329 SUPERFAMILY SSF54593 2 291 3.95E-47 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CO689_RS07370 36929b32d485e66162e3a27edb40a9db 329 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 8 268 2.0E-18 T 28-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CO689_RS07370 36929b32d485e66162e3a27edb40a9db 329 Gene3D G3DSA:3.10.180.10 1 160 7.1E-19 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CO689_RS02885 0b6b98322d1211c2a25ea2591e86a46c 79 Pfam PF10031 Small integral membrane protein (DUF2273) 19 66 8.2E-14 T 28-03-2018 IPR018730 Protein of unknown function DUF2273 CO689_RS00485 0b6b98322d1211c2a25ea2591e86a46c 79 Pfam PF10031 Small integral membrane protein (DUF2273) 19 66 8.2E-14 T 28-03-2018 IPR018730 Protein of unknown function DUF2273 CO689_RS06045 88f0a6de6457e261ce2c81ce623c43b3 503 SUPERFAMILY SSF53067 4 245 7.96E-72 T 28-03-2018 CO689_RS06045 88f0a6de6457e261ce2c81ce623c43b3 503 SUPERFAMILY SSF53067 245 484 6.05E-65 T 28-03-2018 CO689_RS06045 88f0a6de6457e261ce2c81ce623c43b3 503 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 252 437 1.3E-32 T 28-03-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 CO689_RS06045 88f0a6de6457e261ce2c81ce623c43b3 503 Gene3D G3DSA:3.30.420.40 4 240 1.7E-76 T 28-03-2018 CO689_RS06045 88f0a6de6457e261ce2c81ce623c43b3 503 PIRSF PIRSF000538 2 491 7.4E-157 T 28-03-2018 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 CO689_RS06045 88f0a6de6457e261ce2c81ce623c43b3 503 TIGRFAM TIGR01312 XylB: xylulokinase 6 480 1.4E-176 T 28-03-2018 IPR006000 Xylulokinase GO:0004856|GO:0005997 KEGG: 00040+2.7.1.17 CO689_RS06045 88f0a6de6457e261ce2c81ce623c43b3 503 ProSitePatterns PS00445 FGGY family of carbohydrate kinases signature 2. 350 370 - T 28-03-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 CO689_RS06045 88f0a6de6457e261ce2c81ce623c43b3 503 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 4 243 7.6E-70 T 28-03-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 CO689_RS06045 88f0a6de6457e261ce2c81ce623c43b3 503 Gene3D G3DSA:3.30.420.40 241 498 2.8E-64 T 28-03-2018 CO689_RS08995 892c76e6297414f926bdbdcaf6a11c04 324 Pfam PF00268 Ribonucleotide reductase, small chain 5 280 5.4E-66 T 28-03-2018 IPR000358 Ribonucleotide reductase small subunit family GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CO689_RS08995 892c76e6297414f926bdbdcaf6a11c04 324 Gene3D G3DSA:1.10.620.20 2 293 2.6E-64 T 28-03-2018 CO689_RS08995 892c76e6297414f926bdbdcaf6a11c04 324 TIGRFAM TIGR04171 RNR_1b_NrdF: ribonucleoside-diphosphate reductase, class 1b, beta subunit 2 320 9.9E-126 T 28-03-2018 IPR026494 Ribonucleoside reductase subunit beta, NrdF GO:0005971|GO:0009263 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CO689_RS08995 892c76e6297414f926bdbdcaf6a11c04 324 SUPERFAMILY SSF47240 4 318 1.83E-75 T 28-03-2018 IPR009078 Ferritin-like superfamily CO689_RS08795 db8db80e81b461ac207de8b43c616f36 389 Pfam PF07690 Major Facilitator Superfamily 9 345 8.3E-53 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CO689_RS08795 db8db80e81b461ac207de8b43c616f36 389 SUPERFAMILY SSF103473 4 387 1.24E-69 T 28-03-2018 IPR020846 Major facilitator superfamily domain CO689_RS08795 db8db80e81b461ac207de8b43c616f36 389 Gene3D G3DSA:1.20.1250.20 2 187 6.1E-38 T 28-03-2018 CO689_RS08795 db8db80e81b461ac207de8b43c616f36 389 Gene3D G3DSA:1.20.1250.20 198 389 1.5E-22 T 28-03-2018 CO689_RS08795 db8db80e81b461ac207de8b43c616f36 389 PRINTS PR01035 Tetracycline resistance protein signature 329 352 1.4E-23 T 28-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CO689_RS08795 db8db80e81b461ac207de8b43c616f36 389 PRINTS PR01035 Tetracycline resistance protein signature 129 151 1.4E-23 T 28-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CO689_RS08795 db8db80e81b461ac207de8b43c616f36 389 PRINTS PR01035 Tetracycline resistance protein signature 14 30 1.4E-23 T 28-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CO689_RS08795 db8db80e81b461ac207de8b43c616f36 389 PRINTS PR01035 Tetracycline resistance protein signature 157 177 1.4E-23 T 28-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CO689_RS08795 db8db80e81b461ac207de8b43c616f36 389 PRINTS PR01035 Tetracycline resistance protein signature 241 261 1.4E-23 T 28-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CO689_RS08795 db8db80e81b461ac207de8b43c616f36 389 TIGRFAM TIGR00880 2_A_01_02: multidrug resistance protein 41 178 8.1E-40 T 28-03-2018 IPR004734 Multidrug resistance protein GO:0015238|GO:0015893|GO:0016021 Reactome: R-HSA-442660 CO689_RS09060 b62c2cbfc107c9fbdee9f0d04292769d 254 Pfam PF06738 Putative threonine/serine exporter 16 253 7.3E-69 T 28-03-2018 IPR010619 Putative threonine/serine exporter CO689_RS03830 436d5551d118ffb5e9842910fc2c32b5 572 Pfam PF04464 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase 232 534 5.7E-45 T 28-03-2018 IPR007554 CDP-glycerol glycerophosphotransferase GO:0016020|GO:0047355 CO689_RS03830 436d5551d118ffb5e9842910fc2c32b5 572 SUPERFAMILY SSF53756 347 496 1.44E-6 T 28-03-2018 CO689_RS02830 ac83dbd8994c228274055bd6fc665d76 111 SUPERFAMILY SSF54909 2 105 1.82E-21 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel CO689_RS02830 ac83dbd8994c228274055bd6fc665d76 111 Gene3D G3DSA:3.30.70.100 1 108 1.3E-21 T 28-03-2018 CO689_RS02830 ac83dbd8994c228274055bd6fc665d76 111 Pfam PF03992 Antibiotic biosynthesis monooxygenase 2 79 1.2E-15 T 28-03-2018 IPR007138 Antibiotic biosynthesis monooxygenase domain CO689_RS10090 d094f064357975713843e8d0062d2d61 174 TIGRFAM TIGR02227 sigpep_I_bact: signal peptidase I 8 165 1.7E-37 T 28-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 CO689_RS10090 d094f064357975713843e8d0062d2d61 174 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 125 144 7.8E-8 T 28-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 CO689_RS10090 d094f064357975713843e8d0062d2d61 174 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 24 40 7.8E-8 T 28-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 CO689_RS10090 d094f064357975713843e8d0062d2d61 174 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 73 85 7.8E-8 T 28-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 CO689_RS10090 d094f064357975713843e8d0062d2d61 174 Pfam PF00717 Peptidase S24-like 31 93 1.2E-8 T 28-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C CO689_RS10090 d094f064357975713843e8d0062d2d61 174 Gene3D G3DSA:2.10.109.10 20 174 3.6E-29 T 28-03-2018 CO689_RS10090 d094f064357975713843e8d0062d2d61 174 SUPERFAMILY SSF51306 24 170 1.57E-32 T 28-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C CO689_RS10130 9c79f52e5cda94b60173be48f9d90f97 102 Gene3D G3DSA:3.30.300.130 2 101 8.8E-27 T 28-03-2018 IPR034904 Fe-S cluster assembly domain CO689_RS10130 9c79f52e5cda94b60173be48f9d90f97 102 Pfam PF01883 Iron-sulfur cluster assembly protein 6 80 5.5E-21 T 28-03-2018 IPR002744 MIP18 family-like CO689_RS10130 9c79f52e5cda94b60173be48f9d90f97 102 SUPERFAMILY SSF117916 1 100 2.26E-32 T 28-03-2018 IPR034904 Fe-S cluster assembly domain CO689_RS10080 8f7206b638eec0d71eb4393814e2cf7f 443 Pfam PF00342 Phosphoglucose isomerase 76 292 2.0E-19 T 28-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CO689_RS10080 8f7206b638eec0d71eb4393814e2cf7f 443 ProSitePatterns PS00765 Phosphoglucose isomerase signature 1. 197 210 - T 28-03-2018 IPR018189 Phosphoglucose isomerase, conserved site GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CO689_RS10080 8f7206b638eec0d71eb4393814e2cf7f 443 SUPERFAMILY SSF53697 4 442 1.21E-142 T 28-03-2018 CO689_RS10080 8f7206b638eec0d71eb4393814e2cf7f 443 Gene3D G3DSA:3.40.50.10490 1 61 6.5E-10 T 28-03-2018 CO689_RS10080 8f7206b638eec0d71eb4393814e2cf7f 443 Gene3D G3DSA:3.40.50.10490 62 202 3.4E-45 T 28-03-2018 CO689_RS10080 8f7206b638eec0d71eb4393814e2cf7f 443 PRINTS PR00662 Glucose-6-phosphate isomerase signature 371 389 4.9E-25 T 28-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CO689_RS10080 8f7206b638eec0d71eb4393814e2cf7f 443 PRINTS PR00662 Glucose-6-phosphate isomerase signature 193 211 4.9E-25 T 28-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CO689_RS10080 8f7206b638eec0d71eb4393814e2cf7f 443 PRINTS PR00662 Glucose-6-phosphate isomerase signature 403 416 4.9E-25 T 28-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CO689_RS10080 8f7206b638eec0d71eb4393814e2cf7f 443 PRINTS PR00662 Glucose-6-phosphate isomerase signature 76 95 4.9E-25 T 28-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CO689_RS10080 8f7206b638eec0d71eb4393814e2cf7f 443 PRINTS PR00662 Glucose-6-phosphate isomerase signature 389 403 4.9E-25 T 28-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CO689_RS10080 8f7206b638eec0d71eb4393814e2cf7f 443 PRINTS PR00662 Glucose-6-phosphate isomerase signature 268 289 4.9E-25 T 28-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CO689_RS10080 8f7206b638eec0d71eb4393814e2cf7f 443 Hamap MF_00473 Glucose-6-phosphate isomerase [pgi]. 1 430 25.72 T 28-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CO689_RS10080 8f7206b638eec0d71eb4393814e2cf7f 443 ProSitePatterns PS00174 Phosphoglucose isomerase signature 2. 403 420 - T 28-03-2018 IPR018189 Phosphoglucose isomerase, conserved site GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CO689_RS10080 8f7206b638eec0d71eb4393814e2cf7f 443 Gene3D G3DSA:3.40.50.10490 203 429 1.3E-75 T 28-03-2018 CO689_RS05200 a9c1eff58ca7c7d4e449492d71541dfc 484 Pfam PF00367 phosphotransferase system, EIIB 9 42 7.6E-12 T 28-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 CO689_RS05200 a9c1eff58ca7c7d4e449492d71541dfc 484 SUPERFAMILY SSF55604 7 82 7.85E-18 T 28-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 CO689_RS05200 a9c1eff58ca7c7d4e449492d71541dfc 484 Gene3D G3DSA:3.30.1360.60 5 81 8.0E-24 T 28-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 CO689_RS05200 a9c1eff58ca7c7d4e449492d71541dfc 484 ProSitePatterns PS01035 PTS EIIB domains cysteine phosphorylation site signature. 20 37 - T 28-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 CO689_RS05200 a9c1eff58ca7c7d4e449492d71541dfc 484 Pfam PF02378 Phosphotransferase system, EIIC 132 413 5.0E-31 T 28-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 CO689_RS00185 b86282b430e8221d9a0afc4eeb0ac61a 164 SMART SM00347 38 141 9.6E-19 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CO689_RS00185 b86282b430e8221d9a0afc4eeb0ac61a 164 Gene3D G3DSA:1.10.10.10 14 163 1.9E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS00185 b86282b430e8221d9a0afc4eeb0ac61a 164 ProSitePatterns PS01117 MarR-type HTH domain signature. 77 111 - T 28-03-2018 IPR023187 Transcriptional regulator MarR-type, conserved site CO689_RS00185 b86282b430e8221d9a0afc4eeb0ac61a 164 Pfam PF01047 MarR family 45 103 4.3E-14 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CO689_RS00185 b86282b430e8221d9a0afc4eeb0ac61a 164 SUPERFAMILY SSF46785 33 157 4.29E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS02605 5b7d51b1286dbf5bff182e3588bf09f7 418 Gene3D G3DSA:3.40.630.30 1 167 6.0E-29 T 28-03-2018 CO689_RS02605 5b7d51b1286dbf5bff182e3588bf09f7 418 SUPERFAMILY SSF55729 166 244 3.28E-36 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CO689_RS02605 5b7d51b1286dbf5bff182e3588bf09f7 418 SUPERFAMILY SSF55729 310 409 3.28E-36 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CO689_RS02605 5b7d51b1286dbf5bff182e3588bf09f7 418 SUPERFAMILY SSF46589 244 308 3.35E-15 T 28-03-2018 IPR010978 tRNA-binding arm GO:0000166 CO689_RS02605 5b7d51b1286dbf5bff182e3588bf09f7 418 Pfam PF02388 FemAB family 6 413 8.7E-145 T 28-03-2018 IPR003447 FemABX peptidyl transferase GO:0016755|GO:0044038 CO689_RS02605 5b7d51b1286dbf5bff182e3588bf09f7 418 SUPERFAMILY SSF55729 1 164 1.64E-53 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CO689_RS02605 5b7d51b1286dbf5bff182e3588bf09f7 418 Gene3D G3DSA:3.40.630.30 168 389 2.4E-34 T 28-03-2018 CO689_RS13465 ce2c4d102a0d7c7baa7467211cdf6e3b 68 SUPERFAMILY SSF69047 6 65 1.14E-11 T 28-03-2018 IPR008462 CsbD-like domain CO689_RS13465 ce2c4d102a0d7c7baa7467211cdf6e3b 68 Gene3D G3DSA:1.10.1470.10 1 68 1.8E-15 T 28-03-2018 IPR008462 CsbD-like domain CO689_RS13465 ce2c4d102a0d7c7baa7467211cdf6e3b 68 Pfam PF05532 CsbD-like 4 55 1.3E-15 T 28-03-2018 IPR008462 CsbD-like domain CO689_RS11120 f704b141d313185844821ed381d29ffc 195 Gene3D G3DSA:3.90.950.10 1 195 1.3E-71 T 28-03-2018 IPR029001 Inosine triphosphate pyrophosphatase-like CO689_RS11120 f704b141d313185844821ed381d29ffc 195 SUPERFAMILY SSF52972 2 191 3.4E-64 T 28-03-2018 IPR029001 Inosine triphosphate pyrophosphatase-like CO689_RS11120 f704b141d313185844821ed381d29ffc 195 TIGRFAM TIGR00042 TIGR00042: non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family 4 190 3.2E-64 T 28-03-2018 IPR002637 Ham1-like protein GO:0009143|GO:0047429 Reactome: R-HSA-74259 CO689_RS11120 f704b141d313185844821ed381d29ffc 195 Pfam PF01725 Ham1 family 4 188 9.6E-58 T 28-03-2018 IPR002637 Ham1-like protein GO:0009143|GO:0047429 Reactome: R-HSA-74259 CO689_RS11120 f704b141d313185844821ed381d29ffc 195 Hamap MF_01405 dITP/XTP pyrophosphatase [rdgB]. 2 192 45.434 T 28-03-2018 IPR020922 dITP/XTP pyrophosphatase GO:0009143|GO:0017111 CO689_RS12965 6013906d603bb6763bd2c3879a4ed537 330 Pfam PF00676 Dehydrogenase E1 component 19 316 4.1E-83 T 28-03-2018 IPR001017 Dehydrogenase, E1 component GO:0008152|GO:0016624 Reactome: R-HSA-389661 CO689_RS12965 6013906d603bb6763bd2c3879a4ed537 330 SUPERFAMILY SSF52518 4 326 2.95E-91 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CO689_RS12965 6013906d603bb6763bd2c3879a4ed537 330 Gene3D G3DSA:3.40.50.970 2 329 6.8E-76 T 28-03-2018 CO689_RS08250 347f0ae214506ee422ac3c9beaa7041f 127 Pfam PF04241 Protein of unknown function (DUF423) 23 108 1.3E-28 T 28-03-2018 IPR006696 Protein of unknown function DUF423 CO689_RS09950 77d258430fb918de492cdbf8daeefb65 119 Pfam PF01521 Iron-sulphur cluster biosynthesis 5 104 8.9E-19 T 28-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 CO689_RS09950 77d258430fb918de492cdbf8daeefb65 119 ProSitePatterns PS01152 Hypothetical hesB/yadR/yfhF family signature. 90 107 - T 28-03-2018 IPR017870 FeS cluster insertion, C-terminal, conserved site Reactome: R-HSA-1362409 CO689_RS09950 77d258430fb918de492cdbf8daeefb65 119 SUPERFAMILY SSF89360 4 97 1.53E-26 T 28-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 CO689_RS09950 77d258430fb918de492cdbf8daeefb65 119 Gene3D G3DSA:2.60.300.12 3 112 4.3E-34 T 28-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 CO689_RS09950 77d258430fb918de492cdbf8daeefb65 119 TIGRFAM TIGR00049 TIGR00049: iron-sulfur cluster assembly accessory protein 4 108 1.5E-33 T 28-03-2018 IPR016092 FeS cluster insertion protein GO:0005198|GO:0051536|GO:0097428 Reactome: R-HSA-1362409 CO689_RS01070 c3bbb3491c27ff544a490d3948bf208a 105 SMART SM00450 5 101 3.3E-17 T 28-03-2018 IPR001763 Rhodanese-like domain CO689_RS01070 c3bbb3491c27ff544a490d3948bf208a 105 SUPERFAMILY SSF52821 2 102 2.88E-25 T 28-03-2018 IPR001763 Rhodanese-like domain CO689_RS01070 c3bbb3491c27ff544a490d3948bf208a 105 Gene3D G3DSA:3.40.250.10 1 104 3.2E-22 T 28-03-2018 IPR001763 Rhodanese-like domain CO689_RS01070 c3bbb3491c27ff544a490d3948bf208a 105 Pfam PF00581 Rhodanese-like domain 6 96 5.6E-13 T 28-03-2018 IPR001763 Rhodanese-like domain CO689_RS05685 29632c9cc6137a65a21c129c234d255a 295 Gene3D G3DSA:1.10.10.60 125 295 2.7E-4 T 28-03-2018 CO689_RS05685 29632c9cc6137a65a21c129c234d255a 295 SUPERFAMILY SSF88946 38 116 4.71E-5 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CO689_RS09000 ab1698a1e89ae95d460e1a97c1f6f5de 322 Pfam PF01032 FecCD transport family 13 315 4.8E-64 T 28-03-2018 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 CO689_RS09000 ab1698a1e89ae95d460e1a97c1f6f5de 322 SUPERFAMILY SSF81345 4 315 1.7E-65 T 28-03-2018 IPR029022 ABC transporter, BtuC-like CO689_RS09000 ab1698a1e89ae95d460e1a97c1f6f5de 322 Gene3D G3DSA:1.10.3470.10 1 322 3.1E-42 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CO689_RS01610 c699e00b6c5ca915e8a9115146002382 316 SUPERFAMILY SSF51735 99 277 2.92E-42 T 28-03-2018 IPR016040 NAD(P)-binding domain CO689_RS01610 c699e00b6c5ca915e8a9115146002382 316 Gene3D G3DSA:3.40.50.720 1 109 4.0E-19 T 28-03-2018 CO689_RS01610 c699e00b6c5ca915e8a9115146002382 316 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 105 277 9.8E-48 T 28-03-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 CO689_RS01610 c699e00b6c5ca915e8a9115146002382 316 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 11 305 3.5E-13 T 28-03-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 CO689_RS01610 c699e00b6c5ca915e8a9115146002382 316 Gene3D G3DSA:3.40.50.720 110 281 4.8E-39 T 28-03-2018 CO689_RS01610 c699e00b6c5ca915e8a9115146002382 316 SUPERFAMILY SSF52283 13 113 3.19E-15 T 28-03-2018 CO689_RS04885 4be0cafe5d6dab1c0fa1b8d7d6d3cbb2 66 Pfam PF02597 ThiS family 6 66 7.0E-11 T 28-03-2018 IPR003749 ThiamineS/Molybdopterin converting factor subunit 1 Reactome: R-HSA-947581 CO689_RS04885 4be0cafe5d6dab1c0fa1b8d7d6d3cbb2 66 SUPERFAMILY SSF54285 1 66 2.94E-15 T 28-03-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp CO689_RS04885 4be0cafe5d6dab1c0fa1b8d7d6d3cbb2 66 TIGRFAM TIGR01683 thiS: thiamine biosynthesis protein ThiS 3 66 3.6E-20 T 28-03-2018 IPR010035 ThiS, thiamine-biosynthesis CO689_RS04885 4be0cafe5d6dab1c0fa1b8d7d6d3cbb2 66 Gene3D G3DSA:3.10.20.30 1 66 1.3E-17 T 28-03-2018 IPR012675 Beta-grasp domain CO689_RS01700 14b5d913a8875910bff4558cd4fa93f8 68 Pfam PF06569 Protein of unknown function (DUF1128) 3 67 1.5E-24 T 28-03-2018 IPR009507 Protein of unknown function UPF0435 CO689_RS04775 5e862c71ceaa16dcd106042ea5bf738c 349 Gene3D G3DSA:1.10.1530.10 2 79 1.5E-24 T 28-03-2018 CO689_RS04775 5e862c71ceaa16dcd106042ea5bf738c 349 TIGRFAM TIGR03175 AllD: ureidoglycolate dehydrogenase 1 349 8.9E-202 T 28-03-2018 IPR017590 Ureidoglycolate dehydrogenase KEGG: 00062+1.1.1.35|KEGG: 00071+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00230+1.1.1.350|KEGG: 00280+1.1.1.35|KEGG: 00281+1.1.1.35|KEGG: 00310+1.1.1.35|KEGG: 00362+1.1.1.35|KEGG: 00380+1.1.1.35|KEGG: 00623+1.1.1.35|KEGG: 00650+1.1.1.35|KEGG: 00720+1.1.1.35|KEGG: 00930+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5136|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 CO689_RS04775 5e862c71ceaa16dcd106042ea5bf738c 349 Pfam PF02615 Malate/L-lactate dehydrogenase 4 331 2.4E-120 T 28-03-2018 IPR003767 Malate/L-lactate dehydrogenase-like GO:0008152|GO:0016491|GO:0055114 CO689_RS04775 5e862c71ceaa16dcd106042ea5bf738c 349 Gene3D G3DSA:3.30.1370.60 80 305 1.0E-89 T 28-03-2018 CO689_RS04775 5e862c71ceaa16dcd106042ea5bf738c 349 SUPERFAMILY SSF89733 1 333 1.31E-115 T 28-03-2018 IPR003767 Malate/L-lactate dehydrogenase-like GO:0008152|GO:0016491|GO:0055114 CO689_RS10895 778d47932bc5191a5a6e0efd6346fcd6 268 Gene3D G3DSA:1.10.3720.10 6 260 1.6E-30 T 28-03-2018 CO689_RS10895 778d47932bc5191a5a6e0efd6346fcd6 268 SUPERFAMILY SSF161098 12 257 3.55E-42 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CO689_RS09010 de9b52002e0434bf71902c97b925ae75 252 SUPERFAMILY SSF52540 2 225 6.25E-56 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CO689_RS09010 de9b52002e0434bf71902c97b925ae75 252 Pfam PF00005 ABC transporter 17 164 3.5E-29 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CO689_RS09010 de9b52002e0434bf71902c97b925ae75 252 SMART SM00382 26 213 2.6E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain CO689_RS09010 de9b52002e0434bf71902c97b925ae75 252 Gene3D G3DSA:3.40.50.300 1 231 1.5E-56 T 28-03-2018 CO689_RS04970 e9af180b13285a7014162ae7980264bf 243 SMART SM00382 29 208 3.6E-10 T 28-03-2018 IPR003593 AAA+ ATPase domain CO689_RS04970 e9af180b13285a7014162ae7980264bf 243 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CO689_RS04970 e9af180b13285a7014162ae7980264bf 243 Pfam PF00005 ABC transporter 20 161 1.9E-28 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CO689_RS04970 e9af180b13285a7014162ae7980264bf 243 SUPERFAMILY SSF52540 7 224 8.99E-58 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CO689_RS04970 e9af180b13285a7014162ae7980264bf 243 Gene3D G3DSA:3.40.50.300 1 242 4.8E-63 T 28-03-2018 CO689_RS04825 14b8168de51cc4182b5317d8c121cbdd 269 Pfam PF12679 ABC-2 family transporter protein 8 237 1.3E-10 T 28-03-2018 IPR032688 ABC-2 family transporter protein GO:0006810 CO689_RS11260 b12d8c119d928c1afe61c7cf50ba6078 97 Pfam PF02325 YGGT family 16 83 3.0E-20 T 28-03-2018 IPR003425 CCB3/YggT GO:0016020 CO689_RS13880 7345c35d1e94c65b1b293d1ab54da767 229 Gene3D G3DSA:3.60.15.10 1 229 1.2E-37 T 28-03-2018 IPR001279 Metallo-beta-lactamase CO689_RS13880 7345c35d1e94c65b1b293d1ab54da767 229 SMART SM00849 7 195 2.8E-12 T 28-03-2018 IPR001279 Metallo-beta-lactamase CO689_RS13880 7345c35d1e94c65b1b293d1ab54da767 229 SUPERFAMILY SSF56281 1 229 1.31E-40 T 28-03-2018 IPR001279 Metallo-beta-lactamase CO689_RS13880 7345c35d1e94c65b1b293d1ab54da767 229 Pfam PF13483 Beta-lactamase superfamily domain 2 195 1.7E-23 T 28-03-2018 CO689_RS13880 7345c35d1e94c65b1b293d1ab54da767 229 Hamap MF_00457 UPF0173 metal-dependent hydrolase . 1 229 38.265 T 28-03-2018 IPR022877 Protein of unknown funcion UPF0173 CO689_RS05115 eae096acb751121c5151f184e0a9dba6 496 Pfam PF00361 Proton-conducting membrane transporter 128 416 2.0E-47 T 28-03-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CO689_RS05115 eae096acb751121c5151f184e0a9dba6 496 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 132 151 2.5E-12 T 28-03-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CO689_RS05115 eae096acb751121c5151f184e0a9dba6 496 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 321 340 2.5E-12 T 28-03-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CO689_RS05115 eae096acb751121c5151f184e0a9dba6 496 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 162 186 2.5E-12 T 28-03-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CO689_RS05115 eae096acb751121c5151f184e0a9dba6 496 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 233 257 2.5E-12 T 28-03-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CO689_RS05115 eae096acb751121c5151f184e0a9dba6 496 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 373 399 2.5E-12 T 28-03-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CO689_RS01955 3b51dd1414d0622c0d8daff6dea8173e 226 Pfam PF13346 ABC-2 family transporter protein 4 221 4.5E-6 T 28-03-2018 IPR025699 ABC-2 membrane transporter-like CO689_RS01090 41ca9630f5c7ab88982fcb322e6a7220 185 Gene3D G3DSA:3.40.50.150 2 185 4.8E-27 T 28-03-2018 CO689_RS01090 41ca9630f5c7ab88982fcb322e6a7220 185 Pfam PF06962 Putative rRNA methylase 47 183 2.4E-49 T 28-03-2018 IPR010719 Putative rRNA methylase CO689_RS01090 41ca9630f5c7ab88982fcb322e6a7220 185 SUPERFAMILY SSF53335 12 157 3.87E-26 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CO689_RS00805 55e8c993222c0e99650df5ec202d22f9 70 Gene3D G3DSA:2.60.40.1290 1 70 1.3E-19 T 28-03-2018 CO689_RS00805 55e8c993222c0e99650df5ec202d22f9 70 Pfam PF10425 C-terminus of bacterial fibrinogen-binding adhesin 1 66 2.4E-18 T 28-03-2018 IPR011266 Fibrinogen-binding domain 2 GO:0005618|GO:0007155 CO689_RS00805 55e8c993222c0e99650df5ec202d22f9 70 SUPERFAMILY SSF49401 1 65 9.19E-16 T 28-03-2018 IPR008966 Adhesion domain CO689_RS04595 86d339a0fdef5a9188ab0d51175c6072 78 Pfam PF04023 FeoA domain 6 73 5.4E-10 T 28-03-2018 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 CO689_RS04595 86d339a0fdef5a9188ab0d51175c6072 78 SUPERFAMILY SSF50037 7 75 5.49E-12 T 28-03-2018 IPR008988 Transcriptional repressor, C-terminal CO689_RS04595 86d339a0fdef5a9188ab0d51175c6072 78 SMART SM00899 2 75 6.8E-7 T 28-03-2018 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 CO689_RS04595 86d339a0fdef5a9188ab0d51175c6072 78 Gene3D G3DSA:2.30.30.90 5 78 1.1E-11 T 28-03-2018 CO689_RS06000 7470e0ec42f7440c5429bab2c034929d 546 Pfam PF02028 BCCT, betaine/carnitine/choline family transporter 12 497 2.0E-176 T 28-03-2018 IPR000060 BCCT transporter family GO:0005215|GO:0006810|GO:0016020 CO689_RS06000 7470e0ec42f7440c5429bab2c034929d 546 TIGRFAM TIGR00842 bcct: transporter, betaine/carnitine/choline transporter (BCCT) family 50 496 2.9E-140 T 28-03-2018 IPR000060 BCCT transporter family GO:0005215|GO:0006810|GO:0016020 CO689_RS05650 f4a1370abd826d4268c542a7f369e21c 315 Pfam PF00676 Dehydrogenase E1 component 12 302 2.7E-86 T 28-03-2018 IPR001017 Dehydrogenase, E1 component GO:0008152|GO:0016624 Reactome: R-HSA-389661 CO689_RS05650 f4a1370abd826d4268c542a7f369e21c 315 SUPERFAMILY SSF52518 3 314 5.18E-94 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CO689_RS05650 f4a1370abd826d4268c542a7f369e21c 315 Gene3D G3DSA:3.40.50.970 1 315 5.2E-82 T 28-03-2018 CO689_RS08125 459034d8a78917e7b1caa88fe54bd0a8 143 Pfam PF13673 Acetyltransferase (GNAT) domain 36 134 5.0E-13 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CO689_RS08125 459034d8a78917e7b1caa88fe54bd0a8 143 Gene3D G3DSA:3.40.630.30 1 143 4.2E-18 T 28-03-2018 CO689_RS08125 459034d8a78917e7b1caa88fe54bd0a8 143 SUPERFAMILY SSF55729 8 139 4.79E-21 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CO689_RS02275 af283aee033e98791fefadeeb3def970 116 Gene3D G3DSA:2.30.30.110 1 115 1.3E-39 T 28-03-2018 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor CO689_RS02275 af283aee033e98791fefadeeb3def970 116 PIRSF PIRSF033490 1 112 2.0E-38 T 28-03-2018 IPR003477 mRNA interferase PemK-like GO:0003677 CO689_RS02275 af283aee033e98791fefadeeb3def970 116 Pfam PF02452 PemK-like, MazF-like toxin of type II toxin-antitoxin system 3 109 6.3E-34 T 28-03-2018 IPR003477 mRNA interferase PemK-like GO:0003677 CO689_RS02275 af283aee033e98791fefadeeb3def970 116 SUPERFAMILY SSF50118 1 112 4.58E-40 T 28-03-2018 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor CO689_RS08660 e8425399f635baf0ba44319b992ed55d 87 Pfam PF00741 Gas vesicle protein 15 52 2.5E-13 T 28-03-2018 IPR000638 Gas vesicle protein GvpA GO:0005198|GO:0012506 CO689_RS08660 e8425399f635baf0ba44319b992ed55d 87 ProSitePatterns PS00234 Gas vesicles protein GVPa signature 1. 15 29 - T 28-03-2018 IPR018493 Gas vesicle protein GvpA, conserved site GO:0005198|GO:0012506 CO689_RS01005 97da930e4ade42e8dd4504f6d33a62f7 288 Pfam PF07285 Protein of unknown function (DUF1444) 1 263 2.1E-126 T 28-03-2018 IPR010838 Protein of unknown unction DUF1444 CO689_RS01005 97da930e4ade42e8dd4504f6d33a62f7 288 PIRSF PIRSF012562 1 265 4.0E-133 T 28-03-2018 IPR010838 Protein of unknown unction DUF1444 CO689_RS01005 97da930e4ade42e8dd4504f6d33a62f7 288 Hamap MF_01548 UPF0354 protein . 1 266 45.052 T 28-03-2018 IPR010838 Protein of unknown unction DUF1444 CO689_RS08495 e026eddd95accd90dd7d38ab7ea7ef5e 352 SUPERFAMILY SSF53448 1 245 2.19E-42 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CO689_RS08495 e026eddd95accd90dd7d38ab7ea7ef5e 352 Pfam PF00535 Glycosyl transferase family 2 4 131 2.1E-29 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CO689_RS08495 e026eddd95accd90dd7d38ab7ea7ef5e 352 Gene3D G3DSA:3.90.550.10 1 291 1.1E-39 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CO689_RS00430 1446b6076a4882245ce7aab2f8d00a6b 43 Pfam PF05480 Staphylococcus haemolytic protein 1 43 1.8E-13 T 28-03-2018 IPR008846 Staphylococcal hemolytic protein family GO:0009405 CO689_RS04160 13c393ce9c985eefb86e39de39b674cc 198 PIRSF PIRSF021308 1 198 1.2E-84 T 28-03-2018 IPR016786 Uncharacterised protein YdeI, bacterial CO689_RS04160 13c393ce9c985eefb86e39de39b674cc 198 Pfam PF13376 Bacteriocin-protection, YdeI or OmpD-Associated 134 193 1.3E-17 T 28-03-2018 CO689_RS04160 13c393ce9c985eefb86e39de39b674cc 198 Pfam PF08818 Domain of unknown function (DU1801) 20 118 8.2E-16 T 28-03-2018 IPR014922 Domain of unknown function DUF1801 CO689_RS04160 13c393ce9c985eefb86e39de39b674cc 198 SUPERFAMILY SSF159888 9 128 2.22E-20 T 28-03-2018 CO689_RS08395 03191ea33b4a99562af0d44698d0ca5a 70 Pfam PF11148 Protein of unknown function (DUF2922) 3 69 7.4E-18 T 28-03-2018 IPR021321 Protein of unknown function DUF2922 CO689_RS08310 cb3aa0f6ef2e8338a74293c4339d9e19 113 Pfam PF07293 Protein of unknown function (DUF1450) 8 73 9.0E-8 T 28-03-2018 IPR009910 Protein of unknown function DUF1450 CO689_RS08310 cb3aa0f6ef2e8338a74293c4339d9e19 113 Hamap MF_01863 UPF0741 protein . 1 74 30.738 T 28-03-2018 IPR020880 Protein of unknown function UPF0741 CO689_RS04115 48654f9c46d1bfeb71eb10b58f66812f 233 Hamap MF_01142 Antiholin-like protein LrgB [lrgB]. 4 233 30.981 T 28-03-2018 IPR024891 Antiholin-like protein LrgB CO689_RS04115 48654f9c46d1bfeb71eb10b58f66812f 233 Pfam PF04172 LrgB-like family 17 230 4.7E-66 T 28-03-2018 IPR007300 CidB/LrgB family CO689_RS06605 ad26001c69ba20877bb3434e3900ec6b 119 SUPERFAMILY SSF51182 24 111 4.34E-22 T 28-03-2018 IPR011051 RmlC-like cupin domain CO689_RS06605 ad26001c69ba20877bb3434e3900ec6b 119 Gene3D G3DSA:2.60.120.10 6 111 3.3E-21 T 28-03-2018 IPR014710 RmlC-like jelly roll fold CO689_RS06605 ad26001c69ba20877bb3434e3900ec6b 119 Pfam PF07883 Cupin domain 37 104 3.2E-15 T 28-03-2018 IPR013096 Cupin 2, conserved barrel CO689_RS03435 708feef6b15ccb22b7c949ae50c7b707 141 Pfam PF03852 DNA mismatch endonuclease Vsr 5 72 2.1E-24 T 28-03-2018 IPR004603 DNA mismatch endonuclease vsr GO:0004519|GO:0006298 CO689_RS03435 708feef6b15ccb22b7c949ae50c7b707 141 PIRSF PIRSF018267 2 141 8.5E-44 T 28-03-2018 IPR004603 DNA mismatch endonuclease vsr GO:0004519|GO:0006298 CO689_RS03435 708feef6b15ccb22b7c949ae50c7b707 141 TIGRFAM TIGR00632 vsr: DNA mismatch endonuclease Vsr 4 117 1.1E-37 T 28-03-2018 IPR004603 DNA mismatch endonuclease vsr GO:0004519|GO:0006298 CO689_RS03435 708feef6b15ccb22b7c949ae50c7b707 141 SUPERFAMILY SSF52980 4 137 4.83E-38 T 28-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 CO689_RS03435 708feef6b15ccb22b7c949ae50c7b707 141 Gene3D G3DSA:3.40.960.10 20 141 5.5E-29 T 28-03-2018 CO689_RS03435 708feef6b15ccb22b7c949ae50c7b707 141 Pfam PF04480 Protein of unknown function (DUF559) 92 135 3.0E-6 T 28-03-2018 IPR007569 Domain of unknown function DUF559 CO689_RS03910 0ab1018634a5104ef941d3b858d1722c 425 SUPERFAMILY SSF55035 109 215 1.44E-30 T 28-03-2018 IPR009023 Hydroxymethylglutaryl-CoA reductase, class I/II, NAD/NADP-binding domain GO:0050662 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 CO689_RS03910 0ab1018634a5104ef941d3b858d1722c 425 SUPERFAMILY SSF56542 225 424 5.1E-98 T 28-03-2018 IPR009029 Hydroxymethylglutaryl-CoA reductase, class I/II, substrate-binding domain GO:0015936|GO:0016616|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 CO689_RS03910 0ab1018634a5104ef941d3b858d1722c 425 SUPERFAMILY SSF56542 7 117 5.1E-98 T 28-03-2018 IPR009029 Hydroxymethylglutaryl-CoA reductase, class I/II, substrate-binding domain GO:0015936|GO:0016616|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 CO689_RS03910 0ab1018634a5104ef941d3b858d1722c 425 Pfam PF00368 Hydroxymethylglutaryl-coenzyme A reductase 22 382 1.1E-103 T 28-03-2018 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 CO689_RS03910 0ab1018634a5104ef941d3b858d1722c 425 Gene3D G3DSA:3.90.770.10 2 133 1.4E-19 T 28-03-2018 IPR023074 Hydroxymethylglutaryl-CoA reductase, class I/II, catalytic domain GO:0004420|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 CO689_RS03910 0ab1018634a5104ef941d3b858d1722c 425 Gene3D G3DSA:3.90.770.10 134 372 7.9E-55 T 28-03-2018 IPR023074 Hydroxymethylglutaryl-CoA reductase, class I/II, catalytic domain GO:0004420|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 CO689_RS03910 0ab1018634a5104ef941d3b858d1722c 425 PRINTS PR00071 Hydroxymethylglutaryl-coenzyme A reductase signature 310 331 1.2E-7 T 28-03-2018 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 CO689_RS03910 0ab1018634a5104ef941d3b858d1722c 425 PRINTS PR00071 Hydroxymethylglutaryl-coenzyme A reductase signature 169 187 1.2E-7 T 28-03-2018 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 CO689_RS03910 0ab1018634a5104ef941d3b858d1722c 425 PRINTS PR00071 Hydroxymethylglutaryl-coenzyme A reductase signature 48 69 1.2E-7 T 28-03-2018 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 CO689_RS03910 0ab1018634a5104ef941d3b858d1722c 425 PRINTS PR00071 Hydroxymethylglutaryl-coenzyme A reductase signature 75 95 1.2E-7 T 28-03-2018 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 CO689_RS03910 0ab1018634a5104ef941d3b858d1722c 425 TIGRFAM TIGR00532 HMG_CoA_R_NAD: hydroxymethylglutaryl-CoA reductase, degradative 6 381 2.7E-99 T 28-03-2018 IPR004553 Hydroxymethylglutaryl-CoA reductase, bacterial-type GO:0015936|GO:0016616|GO:0050662 CO689_RS01050 38274a337dcff63ee2ef13aa77efc982 138 Gene3D G3DSA:1.20.120.20 14 111 9.2E-5 T 28-03-2018 CO689_RS01050 38274a337dcff63ee2ef13aa77efc982 138 Pfam PF12732 YtxH-like protein 8 70 5.7E-8 T 28-03-2018 IPR024623 Uncharacterised protein family YtxH CO689_RS13690 6b67be3ca1b4e354b2c82423f969779b 358 TIGRFAM TIGR03082 Gneg_AbrB_dup: membrane protein AbrB duplication 193 348 1.5E-34 T 28-03-2018 IPR017516 AbrB duplication CO689_RS13690 6b67be3ca1b4e354b2c82423f969779b 358 TIGRFAM TIGR03082 Gneg_AbrB_dup: membrane protein AbrB duplication 9 164 4.7E-40 T 28-03-2018 IPR017516 AbrB duplication CO689_RS13690 6b67be3ca1b4e354b2c82423f969779b 358 PIRSF PIRSF038991 1 356 3.2E-87 T 28-03-2018 IPR007820 AbrB family GO:0010468|GO:0016021 CO689_RS13690 6b67be3ca1b4e354b2c82423f969779b 358 Pfam PF05145 Transition state regulatory protein AbrB 31 348 5.7E-78 T 28-03-2018 IPR007820 AbrB family GO:0010468|GO:0016021 CO689_RS11835 77392fffb00ceb400bf445c095768e0c 234 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 122 130 1.2E-6 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CO689_RS11835 77392fffb00ceb400bf445c095768e0c 234 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 142 161 1.2E-6 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CO689_RS11835 77392fffb00ceb400bf445c095768e0c 234 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 69 80 1.2E-6 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CO689_RS11835 77392fffb00ceb400bf445c095768e0c 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 142 161 2.1E-26 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CO689_RS11835 77392fffb00ceb400bf445c095768e0c 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 69 80 2.1E-26 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CO689_RS11835 77392fffb00ceb400bf445c095768e0c 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 2 19 2.1E-26 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CO689_RS11835 77392fffb00ceb400bf445c095768e0c 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 196 216 2.1E-26 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CO689_RS11835 77392fffb00ceb400bf445c095768e0c 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 163 180 2.1E-26 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CO689_RS11835 77392fffb00ceb400bf445c095768e0c 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 116 132 2.1E-26 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CO689_RS11835 77392fffb00ceb400bf445c095768e0c 234 Pfam PF00106 short chain dehydrogenase 3 184 4.7E-40 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CO689_RS11835 77392fffb00ceb400bf445c095768e0c 234 Gene3D G3DSA:3.40.50.720 1 234 6.0E-57 T 28-03-2018 CO689_RS11835 77392fffb00ceb400bf445c095768e0c 234 SUPERFAMILY SSF51735 2 234 7.96E-58 T 28-03-2018 IPR016040 NAD(P)-binding domain CO689_RS12530 02735984de7c9efa5cafd38cb36e01c2 263 SUPERFAMILY SSF52540 20 243 5.5E-37 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CO689_RS12530 02735984de7c9efa5cafd38cb36e01c2 263 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 100 118 1.7E-5 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 CO689_RS12530 02735984de7c9efa5cafd38cb36e01c2 263 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 27 45 1.7E-5 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 CO689_RS12530 02735984de7c9efa5cafd38cb36e01c2 263 Pfam PF07728 AAA domain (dynein-related subfamily) 26 164 5.1E-28 T 28-03-2018 IPR011704 ATPase, dynein-related, AAA domain GO:0005524|GO:0016887 CO689_RS12530 02735984de7c9efa5cafd38cb36e01c2 263 Gene3D G3DSA:3.40.50.300 16 170 2.9E-29 T 28-03-2018 CO689_RS12530 02735984de7c9efa5cafd38cb36e01c2 263 SMART SM00382 23 173 0.0012 T 28-03-2018 IPR003593 AAA+ ATPase domain CO689_RS12530 02735984de7c9efa5cafd38cb36e01c2 263 Pfam PF08406 CbbQ/NirQ/NorQ C-terminal 179 258 6.0E-7 T 28-03-2018 IPR013615 CbbQ/NirQ/NorQ, C-terminal CO689_RS05450 7475dfe1a1dc76eeaac80d743eae84c4 435 Pfam PF03605 Anaerobic c4-dicarboxylate membrane transporter 7 372 6.1E-96 T 28-03-2018 IPR004668 Anaerobic c4-dicarboxylate membrane transporter GO:0015556|GO:0015740|GO:0016021 CO689_RS05905 fe1719dda9f2e5c4512632adb324c0c4 162 Pfam PF13273 Protein of unknown function (DUF4064) 3 105 1.3E-18 T 28-03-2018 IPR025273 Domain of unknown function DUF4064 CO689_RS05190 1fcd69b5ce8fdfd7489b9500346f0012 287 PRINTS PR00412 Epoxide hydrolase signature 48 63 5.5E-5 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CO689_RS05190 1fcd69b5ce8fdfd7489b9500346f0012 287 PRINTS PR00412 Epoxide hydrolase signature 262 284 5.5E-5 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CO689_RS05190 1fcd69b5ce8fdfd7489b9500346f0012 287 PRINTS PR00412 Epoxide hydrolase signature 116 129 5.5E-5 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CO689_RS05190 1fcd69b5ce8fdfd7489b9500346f0012 287 Gene3D G3DSA:3.40.50.1820 6 286 3.1E-24 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CO689_RS05190 1fcd69b5ce8fdfd7489b9500346f0012 287 Pfam PF00561 alpha/beta hydrolase fold 23 141 1.7E-12 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CO689_RS05190 1fcd69b5ce8fdfd7489b9500346f0012 287 SUPERFAMILY SSF53474 4 286 7.94E-29 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CO689_RS13135 be89aaf4dbfc71d15adce7bb8d299f94 485 Pfam PF01694 Rhomboid family 198 334 1.1E-33 T 28-03-2018 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 CO689_RS13135 be89aaf4dbfc71d15adce7bb8d299f94 485 SUPERFAMILY SSF144091 154 338 2.88E-43 T 28-03-2018 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 CO689_RS13135 be89aaf4dbfc71d15adce7bb8d299f94 485 SUPERFAMILY SSF48452 368 479 3.21E-16 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CO689_RS13135 be89aaf4dbfc71d15adce7bb8d299f94 485 Gene3D G3DSA:1.25.40.10 357 484 7.7E-13 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CO689_RS13135 be89aaf4dbfc71d15adce7bb8d299f94 485 Gene3D G3DSA:1.20.1540.10 153 337 4.6E-41 T 28-03-2018 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 CO689_RS09660 7663f3fcdf89711d9a0ed8dc4d0b60d5 145 Pfam PF11753 Protein of unknwon function (DUF3310) 77 136 6.8E-13 T 28-03-2018 IPR021739 SaV-like CO689_RS07940 6d736ddc688894524d8233f6053e98ed 153 PIRSF PIRSF010607 1 153 7.4E-65 T 28-03-2018 IPR008463 Transcriptional repressor of class III stress genes GO:0003677|GO:0006355|GO:0006950 CO689_RS07940 6d736ddc688894524d8233f6053e98ed 153 Pfam PF05848 Firmicute transcriptional repressor of class III stress genes (CtsR) 3 148 1.0E-56 T 28-03-2018 IPR008463 Transcriptional repressor of class III stress genes GO:0003677|GO:0006355|GO:0006950 CO689_RS09910 f6012a572ee5557ba02275bebaa2e9fd 404 TIGRFAM TIGR04091 LTA_dltB: D-alanyl-lipoteichoic acid biosynthesis protein DltB 3 403 3.0E-151 T 28-03-2018 IPR024024 D-alanyl transfer protein DltB CO689_RS09910 f6012a572ee5557ba02275bebaa2e9fd 404 Pfam PF03062 MBOAT, membrane-bound O-acyltransferase family 90 395 5.6E-18 T 28-03-2018 IPR004299 Membrane bound O-acyl transferase, MBOAT CO689_RS09910 f6012a572ee5557ba02275bebaa2e9fd 404 PIRSF PIRSF500216 1 404 2.7E-160 T 28-03-2018 IPR024024 D-alanyl transfer protein DltB CO689_RS09910 f6012a572ee5557ba02275bebaa2e9fd 404 PIRSF PIRSF016636 3 403 1.6E-75 T 28-03-2018 IPR024194 Alginate O-acetyltransferase AlgI/D-alanyl transfer protein DltB CO689_RS12115 69691fdee859c519ec01cb986277e3d7 485 PIRSF PIRSF006060 1 485 1.6E-76 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CO689_RS12115 69691fdee859c519ec01cb986277e3d7 485 ProSitePatterns PS00218 Amino acid permeases signature. 39 70 - T 28-03-2018 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 CO689_RS12115 69691fdee859c519ec01cb986277e3d7 485 Pfam PF00324 Amino acid permease 14 469 3.0E-118 T 28-03-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0006810|GO:0016020|GO:0055085 CO689_RS12395 fcd43dce36016d7f42f10f198839a430 493 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 67 410 3.6E-59 T 28-03-2018 IPR000914 Solute-binding protein family 5 domain CO689_RS12395 fcd43dce36016d7f42f10f198839a430 493 PIRSF PIRSF002741 39 493 6.0E-72 T 28-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 CO689_RS12395 fcd43dce36016d7f42f10f198839a430 493 Gene3D G3DSA:3.10.105.10 270 463 7.7E-35 T 28-03-2018 CO689_RS12395 fcd43dce36016d7f42f10f198839a430 493 SUPERFAMILY SSF53850 48 485 2.35E-85 T 28-03-2018 CO689_RS12395 fcd43dce36016d7f42f10f198839a430 493 Gene3D G3DSA:3.90.76.10 57 145 1.5E-13 T 28-03-2018 CO689_RS12395 fcd43dce36016d7f42f10f198839a430 493 Gene3D G3DSA:3.40.190.10 146 269 1.7E-28 T 28-03-2018 CO689_RS01320 a313cac8a0edadebfb206079544f2233 318 Pfam PF00762 Ferrochelatase 5 305 1.2E-78 T 28-03-2018 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 CO689_RS01320 a313cac8a0edadebfb206079544f2233 318 TIGRFAM TIGR00109 hemH: ferrochelatase 4 306 7.5E-84 T 28-03-2018 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 CO689_RS01320 a313cac8a0edadebfb206079544f2233 318 Gene3D G3DSA:3.40.50.1400 158 290 4.1E-35 T 28-03-2018 CO689_RS01320 a313cac8a0edadebfb206079544f2233 318 SUPERFAMILY SSF53800 4 307 3.76E-81 T 28-03-2018 CO689_RS01320 a313cac8a0edadebfb206079544f2233 318 ProSitePatterns PS00534 Ferrochelatase signature. 178 197 - T 28-03-2018 IPR019772 Ferrochelatase, active site GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 CO689_RS01320 a313cac8a0edadebfb206079544f2233 318 Gene3D G3DSA:3.40.50.1400 1 157 6.3E-25 T 28-03-2018 CO689_RS01320 a313cac8a0edadebfb206079544f2233 318 Hamap MF_00323 Ferrochelatase [hemH]. 3 309 30.996 T 28-03-2018 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 CO689_RS06585 e1cf03f27f8d61e943acc6e251062186 317 SUPERFAMILY SSF51679 23 305 1.43E-49 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CO689_RS06585 e1cf03f27f8d61e943acc6e251062186 317 Gene3D G3DSA:3.20.20.30 1 237 3.8E-44 T 28-03-2018 CO689_RS06585 e1cf03f27f8d61e943acc6e251062186 317 TIGRFAM TIGR03571 lucif_BA3436: luciferase-type oxidoreductase, BA3436 family 9 308 2.7E-117 T 28-03-2018 IPR020020 Luciferase-type oxidoreductase CO689_RS06585 e1cf03f27f8d61e943acc6e251062186 317 Pfam PF00296 Luciferase-like monooxygenase 25 227 4.0E-34 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CO689_RS05100 c1ad38dcfdd7d30504fc7ec9098fb6f5 156 Pfam PF03334 Na+/H+ antiporter subunit 14 95 2.8E-22 T 28-03-2018 IPR005133 Na+/H+ antiporter subunit G GO:0005451|GO:0015672|GO:0015992 CO689_RS05100 c1ad38dcfdd7d30504fc7ec9098fb6f5 156 TIGRFAM TIGR01300 CPA3_mnhG_phaG: monovalent cation/proton antiporter, MnhG/PhaG subunit 13 102 4.3E-22 T 28-03-2018 IPR005133 Na+/H+ antiporter subunit G GO:0005451|GO:0015672|GO:0015992 CO689_RS02440 82b778f42f98e2ba0a2d9d47941ecf31 134 Pfam PF00401 ATP synthase, Delta/Epsilon chain, long alpha-helix domain 87 132 7.6E-14 T 28-03-2018 IPR020547 ATP synthase delta/epsilon subunit, C-terminal domain Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CO689_RS02440 82b778f42f98e2ba0a2d9d47941ecf31 134 Gene3D G3DSA:1.20.5.440 90 132 1.4E-14 T 28-03-2018 CO689_RS02440 82b778f42f98e2ba0a2d9d47941ecf31 134 ProDom PD000944 ATP SYNTHASE ION EPSILON SUBUNIT HYDROLASE CF1 SYNTHESIS CHAIN HYDROGEN 9 89 5.0E-27 T 28-03-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CO689_RS02440 82b778f42f98e2ba0a2d9d47941ecf31 134 Pfam PF02823 ATP synthase, Delta/Epsilon chain, beta-sandwich domain 4 83 2.8E-20 T 28-03-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CO689_RS02440 82b778f42f98e2ba0a2d9d47941ecf31 134 Gene3D G3DSA:2.60.15.10 1 89 4.0E-23 T 28-03-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CO689_RS02440 82b778f42f98e2ba0a2d9d47941ecf31 134 SUPERFAMILY SSF51344 3 84 1.83E-20 T 28-03-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CO689_RS02440 82b778f42f98e2ba0a2d9d47941ecf31 134 SUPERFAMILY SSF46604 87 132 2.43E-8 T 28-03-2018 IPR020547 ATP synthase delta/epsilon subunit, C-terminal domain Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CO689_RS02440 82b778f42f98e2ba0a2d9d47941ecf31 134 Hamap MF_00530 ATP synthase epsilon chain [atpC]. 2 130 21.137 T 28-03-2018 IPR001469 ATP synthase, F1 complex, delta/epsilon subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CO689_RS02440 82b778f42f98e2ba0a2d9d47941ecf31 134 TIGRFAM TIGR01216 ATP_synt_epsi: ATP synthase F1, epsilon subunit 3 131 7.6E-32 T 28-03-2018 IPR001469 ATP synthase, F1 complex, delta/epsilon subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CO689_RS12665 a81c8d6d92f974d39e3d0150e9ea9009 374 SUPERFAMILY SSF53335 253 369 1.86E-38 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CO689_RS12665 a81c8d6d92f974d39e3d0150e9ea9009 374 SUPERFAMILY SSF53335 142 216 1.86E-38 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CO689_RS12665 a81c8d6d92f974d39e3d0150e9ea9009 374 Pfam PF02926 THUMP domain 26 153 2.0E-12 T 28-03-2018 IPR004114 THUMP domain GO:0003723 CO689_RS12665 a81c8d6d92f974d39e3d0150e9ea9009 374 ProSitePatterns PS01261 Uncharacterized protein family UPF0020 signature. 194 205 - T 28-03-2018 IPR000241 Putative RNA methylase domain KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CO689_RS12665 a81c8d6d92f974d39e3d0150e9ea9009 374 SMART SM00981 55 153 1.2E-9 T 28-03-2018 IPR004114 THUMP domain GO:0003723 CO689_RS12665 a81c8d6d92f974d39e3d0150e9ea9009 374 Pfam PF01170 Putative RNA methylase family UPF0020 161 367 3.9E-55 T 28-03-2018 IPR000241 Putative RNA methylase domain KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CO689_RS12665 a81c8d6d92f974d39e3d0150e9ea9009 374 Gene3D G3DSA:3.40.50.150 159 374 9.6E-33 T 28-03-2018 CO689_RS11585 88aa25bb017a781c695b124eba28c4cf 104 SUPERFAMILY SSF159121 32 104 4.97E-6 T 28-03-2018 IPR006542 Protein of unknown function DUF1093 CO689_RS11585 88aa25bb017a781c695b124eba28c4cf 104 TIGRFAM TIGR01655 yxeA_fam: conserved hypothetical protein 1 103 5.7E-15 T 28-03-2018 IPR006542 Protein of unknown function DUF1093 CO689_RS06830 cca04560d1bbe216627ba8f07425d3ff 116 Pfam PF06106 S. aureus uracil DNA glycosylase inhibitor 2 112 1.4E-71 T 28-03-2018 IPR009295 Uracil DNA glycosylase inhibitor CO689_RS06575 961048715536a41d788110b7a4416d8d 248 SUPERFAMILY SSF52467 5 246 7.36E-71 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CO689_RS06575 961048715536a41d788110b7a4416d8d 248 Pfam PF02146 Sir2 family 26 202 1.2E-46 T 28-03-2018 IPR003000 Sirtuin family GO:0070403 CO689_RS06575 961048715536a41d788110b7a4416d8d 248 Gene3D G3DSA:3.40.50.1220 2 246 4.3E-53 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CO689_RS03600 f8e4b40c84b69d063abcb6a3c1bcb51a 173 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 21 163 2.0E-21 T 28-03-2018 IPR013538 Activator of Hsp90 ATPase homologue 1-like GO:0006950 CO689_RS03600 f8e4b40c84b69d063abcb6a3c1bcb51a 173 Gene3D G3DSA:3.30.530.20 12 173 2.3E-20 T 28-03-2018 IPR023393 START-like domain CO689_RS03600 f8e4b40c84b69d063abcb6a3c1bcb51a 173 SUPERFAMILY SSF55961 6 165 1.81E-29 T 28-03-2018 CO689_RS13540 1a3f845612a324eb06c7a09d0f2d725f 341 SUPERFAMILY SSF111337 2 341 1.7E-139 T 28-03-2018 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 CO689_RS13540 1a3f845612a324eb06c7a09d0f2d725f 341 Gene3D G3DSA:3.40.1780.10 1 133 7.7E-44 T 28-03-2018 CO689_RS13540 1a3f845612a324eb06c7a09d0f2d725f 341 Gene3D G3DSA:3.40.1780.10 173 341 6.5E-68 T 28-03-2018 CO689_RS13540 1a3f845612a324eb06c7a09d0f2d725f 341 Hamap MF_00113 S-adenosylmethionine:tRNA ribosyltransferase-isomerase [queA]. 1 341 46.629 T 28-03-2018 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 CO689_RS13540 1a3f845612a324eb06c7a09d0f2d725f 341 TIGRFAM TIGR00113 queA: S-adenosylmethionine:tRNA ribosyltransferase-isomerase 2 341 8.7E-147 T 28-03-2018 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 CO689_RS13540 1a3f845612a324eb06c7a09d0f2d725f 341 Pfam PF02547 Queuosine biosynthesis protein 4 340 1.1E-142 T 28-03-2018 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 CO689_RS13795 4c04aeae01e03dfd15b6909cff31b291 204 Pfam PF01121 Dephospho-CoA kinase 4 181 2.1E-58 T 28-03-2018 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|MetaCyc: PWY-7851 CO689_RS13795 4c04aeae01e03dfd15b6909cff31b291 204 Hamap MF_00376 Dephospho-CoA kinase [coaE]. 2 198 27.623 T 28-03-2018 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|MetaCyc: PWY-7851 CO689_RS13795 4c04aeae01e03dfd15b6909cff31b291 204 SUPERFAMILY SSF52540 1 191 2.11E-38 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CO689_RS13795 4c04aeae01e03dfd15b6909cff31b291 204 TIGRFAM TIGR00152 TIGR00152: dephospho-CoA kinase 4 189 8.6E-60 T 28-03-2018 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|MetaCyc: PWY-7851 CO689_RS13795 4c04aeae01e03dfd15b6909cff31b291 204 Gene3D G3DSA:3.40.50.300 2 202 1.6E-42 T 28-03-2018 CO689_RS07690 9886ca6e8ae4604c638dd5206cab7066 87 PIRSF PIRSF037257 1 85 1.3E-36 T 28-03-2018 IPR009366 Protein Veg GO:0042710 CO689_RS07690 9886ca6e8ae4604c638dd5206cab7066 87 Pfam PF06257 Biofilm formation stimulator VEG 4 74 1.4E-30 T 28-03-2018 IPR009366 Protein Veg GO:0042710 CO689_RS07690 9886ca6e8ae4604c638dd5206cab7066 87 Gene3D G3DSA:2.30.30.100 2 76 8.9E-32 T 28-03-2018 CO689_RS12615 3339f0cde53ea9649d8bc19900fc5127 159 PRINTS PR00070 Dihydrofolate reductase signature 41 52 1.5E-12 T 28-03-2018 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 CO689_RS12615 3339f0cde53ea9649d8bc19900fc5127 159 PRINTS PR00070 Dihydrofolate reductase signature 89 103 1.5E-12 T 28-03-2018 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 CO689_RS12615 3339f0cde53ea9649d8bc19900fc5127 159 PRINTS PR00070 Dihydrofolate reductase signature 14 24 1.5E-12 T 28-03-2018 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 CO689_RS12615 3339f0cde53ea9649d8bc19900fc5127 159 PRINTS PR00070 Dihydrofolate reductase signature 28 36 1.5E-12 T 28-03-2018 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 CO689_RS12615 3339f0cde53ea9649d8bc19900fc5127 159 ProSitePatterns PS00075 Dihydrofolate reductase (DHFR) domain signature. 14 36 - T 28-03-2018 IPR017925 Dihydrofolate reductase conserved site GO:0004146|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-1474151|Reactome: R-HSA-196757|Reactome: R-HSA-539107 CO689_RS12615 3339f0cde53ea9649d8bc19900fc5127 159 Gene3D G3DSA:3.40.430.10 1 159 1.3E-48 T 28-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 CO689_RS12615 3339f0cde53ea9649d8bc19900fc5127 159 SUPERFAMILY SSF53597 2 158 6.59E-52 T 28-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 CO689_RS12615 3339f0cde53ea9649d8bc19900fc5127 159 PIRSF PIRSF000194 1 159 4.2E-52 T 28-03-2018 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 CO689_RS12615 3339f0cde53ea9649d8bc19900fc5127 159 Pfam PF00186 Dihydrofolate reductase 3 157 8.6E-56 T 28-03-2018 IPR001796 Dihydrofolate reductase domain GO:0004146|GO:0006545|GO:0009165|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 CO689_RS08865 488e46d9e3e2379cf8c05b6a8b1fb8f6 765 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 289 710 2.0E-62 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CO689_RS08865 488e46d9e3e2379cf8c05b6a8b1fb8f6 765 SUPERFAMILY SSF81442 284 759 3.79E-77 T 28-03-2018 IPR023616 Cytochrome c oxidase-like, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CO689_RS08865 488e46d9e3e2379cf8c05b6a8b1fb8f6 765 Gene3D G3DSA:1.20.210.10 276 753 6.6E-61 T 28-03-2018 IPR023616 Cytochrome c oxidase-like, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CO689_RS10190 202cb357f49cf3696b43f09477500b8d 328 TIGRFAM TIGR03558 oxido_grp_1: luciferase family oxidoreductase, group 1 4 325 2.0E-79 T 28-03-2018 IPR019949 Luciferase family oxidoreductase, group 1 CO689_RS10190 202cb357f49cf3696b43f09477500b8d 328 Gene3D G3DSA:3.20.20.30 9 327 7.2E-44 T 28-03-2018 CO689_RS10190 202cb357f49cf3696b43f09477500b8d 328 SUPERFAMILY SSF51679 2 325 2.36E-47 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CO689_RS10190 202cb357f49cf3696b43f09477500b8d 328 Pfam PF00296 Luciferase-like monooxygenase 16 215 3.0E-25 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CO689_RS01930 453db15b556124ca6dce52c93b52709e 186 Pfam PF08006 Protein of unknown function (DUF1700) 2 182 7.7E-55 T 28-03-2018 IPR012963 Protein of unknown function DUF1700 CO689_RS04225 51e04f8e3b84509bf87da6277eb5d084 453 TIGRFAM TIGR00791 gntP: transporter, gluconate:H+ symporter (GntP) family 7 453 8.2E-182 T 28-03-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 CO689_RS04225 51e04f8e3b84509bf87da6277eb5d084 453 PIRSF PIRSF002746 2 453 1.2E-172 T 28-03-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 CO689_RS04225 51e04f8e3b84509bf87da6277eb5d084 453 Pfam PF02447 GntP family permease 6 451 2.7E-171 T 28-03-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 CO689_RS03200 2c04b27133909775d3fc222a6aaf927c 55 Gene3D G3DSA:1.10.287.510 1 55 2.0E-4 T 28-03-2018 CO689_RS01175 09b0a087b6f749c840d4e44f2c76c025 117 Pfam PF02537 CrcB-like protein, Camphor Resistance (CrcB) 5 113 1.2E-20 T 28-03-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 CO689_RS01175 09b0a087b6f749c840d4e44f2c76c025 117 Hamap MF_00454 Putative fluoride ion transporter CrcB [crcB]. 4 117 16.765 T 28-03-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 CO689_RS06500 f5448dd559b6efb7a8095beea283f292 249 Gene3D G3DSA:3.20.20.150 1 247 2.9E-24 T 28-03-2018 CO689_RS06500 f5448dd559b6efb7a8095beea283f292 249 SUPERFAMILY SSF51658 4 237 2.32E-44 T 28-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain CO689_RS05830 c7f2854de9e08831b496e3b95290cf92 141 Gene3D G3DSA:2.30.110.10 4 141 9.1E-17 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CO689_RS05830 c7f2854de9e08831b496e3b95290cf92 141 SUPERFAMILY SSF50475 7 131 1.74E-20 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CO689_RS05830 c7f2854de9e08831b496e3b95290cf92 141 Pfam PF16242 Pyridoxamine 5'-phosphate oxidase like 8 122 8.3E-16 T 28-03-2018 CO689_RS10505 f7719af56096e76908a383a694ba2fb9 68 Pfam PF05154 TM2 domain 1 51 4.2E-17 T 28-03-2018 IPR007829 TM2 domain CO689_RS11190 e64748ac1ebe9ecd0aa5959681cac898 148 Pfam PF13673 Acetyltransferase (GNAT) domain 33 133 2.6E-7 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CO689_RS11190 e64748ac1ebe9ecd0aa5959681cac898 148 Gene3D G3DSA:3.40.630.30 1 147 1.0E-16 T 28-03-2018 CO689_RS11190 e64748ac1ebe9ecd0aa5959681cac898 148 SUPERFAMILY SSF55729 24 134 2.49E-13 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CO689_RS11190 e64748ac1ebe9ecd0aa5959681cac898 148 PIRSF PIRSF037732 1 148 4.0E-45 T 28-03-2018 IPR017274 Putative N-acetyltransferase YlbP CO689_RS06005 6850ee3945f8a92e22506288183b3dcb 326 SUPERFAMILY SSF53850 35 244 1.61E-9 T 28-03-2018 CO689_RS06005 6850ee3945f8a92e22506288183b3dcb 326 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 53 325 7.9E-28 T 28-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CO689_RS06005 6850ee3945f8a92e22506288183b3dcb 326 Gene3D G3DSA:3.40.190.10 147 303 2.5E-12 T 28-03-2018 CO689_RS06005 6850ee3945f8a92e22506288183b3dcb 326 PIRSF PIRSF017082 2 326 3.0E-99 T 28-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CO689_RS03275 c6db39cd849da095277df0b1e20402d2 340 Pfam PF04055 Radical SAM superfamily 19 182 7.2E-27 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CO689_RS03275 c6db39cd849da095277df0b1e20402d2 340 Pfam PF13353 4Fe-4S single cluster domain 22 128 1.0E-7 T 28-03-2018 CO689_RS03275 c6db39cd849da095277df0b1e20402d2 340 Hamap MF_01225_B GTP 3',8-cyclase [moaA]. 5 340 40.94 T 28-03-2018 IPR013483 Molybdenum cofactor biosynthesis protein A GO:0006777|GO:0046872 Reactome: R-HSA-947581 CO689_RS03275 c6db39cd849da095277df0b1e20402d2 340 Gene3D G3DSA:3.20.20.70 1 340 1.1E-82 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CO689_RS03275 c6db39cd849da095277df0b1e20402d2 340 SUPERFAMILY SSF102114 6 308 8.11E-81 T 28-03-2018 CO689_RS03275 c6db39cd849da095277df0b1e20402d2 340 TIGRFAM TIGR02666 moaA: molybdenum cofactor biosynthesis protein A 6 340 1.7E-119 T 28-03-2018 IPR013483 Molybdenum cofactor biosynthesis protein A GO:0006777|GO:0046872 Reactome: R-HSA-947581 CO689_RS03275 c6db39cd849da095277df0b1e20402d2 340 ProSitePatterns PS01305 moaA / nifB / pqqE family signature. 20 31 - T 28-03-2018 IPR000385 MoaA/nifB/pqqE, iron-sulphur binding, conserved site GO:0003824|GO:0046872|GO:0051539 Reactome: R-HSA-947581 CO689_RS03275 c6db39cd849da095277df0b1e20402d2 340 SMART SM00729 14 222 1.0E-7 T 28-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 CO689_RS03275 c6db39cd849da095277df0b1e20402d2 340 Pfam PF06463 Molybdenum Cofactor Synthesis C 190 317 8.6E-37 T 28-03-2018 IPR010505 Molybdenum cofactor synthesis C-terminal GO:0006777|GO:0019008|GO:0051539 Reactome: R-HSA-947581 CO689_RS05525 47a38ebe3eef596d1ff025a2977c881a 286 Gene3D G3DSA:3.40.190.10 1 243 3.3E-4 T 28-03-2018 CO689_RS06200 0581abeb697f2621581dba8db2764cd7 237 Pfam PF13240 zinc-ribbon domain 3 24 5.2E-8 T 28-03-2018 IPR026870 Zinc-ribbon domain Reactome: R-HSA-202670 CO689_RS06200 0581abeb697f2621581dba8db2764cd7 237 Gene3D G3DSA:2.20.28.20 2 16 0.011 T 28-03-2018 CO689_RS05740 9c6a3c104de4424afeb22925de70f346 532 SUPERFAMILY SSF56235 51 528 1.2E-90 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CO689_RS05740 9c6a3c104de4424afeb22925de70f346 532 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 271 290 1.9E-33 T 28-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CO689_RS05740 9c6a3c104de4424afeb22925de70f346 532 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 437 454 1.9E-33 T 28-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CO689_RS05740 9c6a3c104de4424afeb22925de70f346 532 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 133 151 1.9E-33 T 28-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CO689_RS05740 9c6a3c104de4424afeb22925de70f346 532 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 360 378 1.9E-33 T 28-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CO689_RS05740 9c6a3c104de4424afeb22925de70f346 532 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 414 429 1.9E-33 T 28-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CO689_RS05740 9c6a3c104de4424afeb22925de70f346 532 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 76 101 1.9E-33 T 28-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CO689_RS05740 9c6a3c104de4424afeb22925de70f346 532 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 151 170 1.9E-33 T 28-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CO689_RS05740 9c6a3c104de4424afeb22925de70f346 532 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 242 258 1.9E-33 T 28-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CO689_RS05740 9c6a3c104de4424afeb22925de70f346 532 Pfam PF01019 Gamma-glutamyltranspeptidase 69 516 1.7E-73 T 28-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CO689_RS11850 40a3a9d6c19518cec2c091d77e0e505b 193 TIGRFAM TIGR00560 pgsA: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase 1 190 1.2E-56 T 28-03-2018 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668|MetaCyc: PWY-7817 CO689_RS11850 40a3a9d6c19518cec2c091d77e0e505b 193 Pfam PF01066 CDP-alcohol phosphatidyltransferase 2 82 2.4E-16 T 28-03-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 CO689_RS11850 40a3a9d6c19518cec2c091d77e0e505b 193 PIRSF PIRSF000847 1 193 1.3E-49 T 28-03-2018 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668|MetaCyc: PWY-7817 CO689_RS11850 40a3a9d6c19518cec2c091d77e0e505b 193 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 60 82 - T 28-03-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 CO689_RS02840 77646859002d37bcba8b14f44a0f995c 320 SUPERFAMILY SSF81345 3 319 9.94E-77 T 28-03-2018 IPR029022 ABC transporter, BtuC-like CO689_RS02840 77646859002d37bcba8b14f44a0f995c 320 Gene3D G3DSA:1.10.3470.10 2 320 1.8E-64 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CO689_RS02840 77646859002d37bcba8b14f44a0f995c 320 Pfam PF01032 FecCD transport family 15 319 2.8E-86 T 28-03-2018 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 CO689_RS07130 c559317e497d2ea329841b7bf2ce06e9 112 SUPERFAMILY SSF50118 2 107 1.4E-25 T 28-03-2018 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor CO689_RS07130 c559317e497d2ea329841b7bf2ce06e9 112 Gene3D G3DSA:2.30.30.110 1 107 7.0E-23 T 28-03-2018 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor CO689_RS07130 c559317e497d2ea329841b7bf2ce06e9 112 Pfam PF02452 PemK-like, MazF-like toxin of type II toxin-antitoxin system 3 106 2.0E-20 T 28-03-2018 IPR003477 mRNA interferase PemK-like GO:0003677 CO689_RS03800 087360f4be8676938325f515d0feb22a 352 Pfam PF12704 MacB-like periplasmic core domain 16 175 1.4E-8 T 28-03-2018 IPR025857 MacB-like periplasmic core domain CO689_RS03800 087360f4be8676938325f515d0feb22a 352 Pfam PF02687 FtsX-like permease family 259 344 6.8E-7 T 28-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 CO689_RS11840 d6d944c7c830a7db05b4ff2d110184cb 287 SUPERFAMILY SSF55021 10 71 4.12E-5 T 28-03-2018 CO689_RS11840 d6d944c7c830a7db05b4ff2d110184cb 287 PIRSF PIRSF021288 5 279 8.6E-140 T 28-03-2018 IPR016784 Uncharacterised protein UCP021288 with ACT domain CO689_RS11840 d6d944c7c830a7db05b4ff2d110184cb 287 Pfam PF11868 Protein of unknown function (DUF3388) 76 262 2.3E-96 T 28-03-2018 IPR024514 Domain of unknown function DUF3388 CO689_RS09990 a581f28c9a16300003d721963c427fa0 159 Pfam PF01899 Na+/H+ ion antiporter subunit 8 156 5.3E-42 T 28-03-2018 IPR002758 Na+/H+ antiporter subunit E GO:0006812|GO:0008324|GO:0016021 CO689_RS09990 a581f28c9a16300003d721963c427fa0 159 PIRSF PIRSF019239 1 159 3.5E-45 T 28-03-2018 IPR002758 Na+/H+ antiporter subunit E GO:0006812|GO:0008324|GO:0016021 CO689_RS09885 71d5b59dde28f257d2064bac8d2056a0 144 Gene3D G3DSA:1.20.120.580 1 139 4.5E-28 T 28-03-2018 IPR008201 Protein of unknown function DUF86 CO689_RS09885 71d5b59dde28f257d2064bac8d2056a0 144 Pfam PF01934 Protein of unknown function DUF86 20 123 5.3E-18 T 28-03-2018 IPR008201 Protein of unknown function DUF86 CO689_RS03015 a64673721c492fa213dd810b69c4906e 122 Pfam PF01196 Ribosomal protein L17 16 122 2.0E-37 T 28-03-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CO689_RS03015 a64673721c492fa213dd810b69c4906e 122 Gene3D G3DSA:3.90.1030.10 1 122 3.8E-46 T 28-03-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CO689_RS03015 a64673721c492fa213dd810b69c4906e 122 TIGRFAM TIGR00059 L17: ribosomal protein bL17 2 122 1.1E-44 T 28-03-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CO689_RS03015 a64673721c492fa213dd810b69c4906e 122 ProSitePatterns PS01167 Ribosomal protein L17 signature. 30 52 - T 28-03-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CO689_RS03015 a64673721c492fa213dd810b69c4906e 122 Hamap MF_01368 50S ribosomal protein L17 [rplQ]. 1 122 27.429 T 28-03-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CO689_RS03015 a64673721c492fa213dd810b69c4906e 122 SUPERFAMILY SSF64263 2 122 2.49E-43 T 28-03-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CO689_RS11770 6a5e314df2cb153a28255f2669eca0c4 457 Pfam PF00939 Sodium:sulfate symporter transmembrane region 4 451 2.5E-27 T 28-03-2018 IPR001898 Solute carrier family 13 GO:0005215|GO:0006814|GO:0016020|GO:0055085 Reactome: R-HSA-433137 CO689_RS03365 6101c81b4bc5cef8953834defd03eac0 183 PIRSF PIRSF016661 1 180 6.0E-36 T 28-03-2018 IPR003784 BioY protein GO:0005886|GO:0015225|GO:0015878 CO689_RS03365 6101c81b4bc5cef8953834defd03eac0 183 Pfam PF02632 BioY family 29 171 9.6E-32 T 28-03-2018 IPR003784 BioY protein GO:0005886|GO:0015225|GO:0015878 CO689_RS08340 4dc216ca8a76be13fbd3a0d3c31b6b9a 138 Pfam PF09148 Domain of unknown function (DUF1934) 5 132 1.7E-29 T 28-03-2018 IPR015231 Protein of unknown function DUF1934 CO689_RS08340 4dc216ca8a76be13fbd3a0d3c31b6b9a 138 SUPERFAMILY SSF50814 4 136 1.62E-33 T 28-03-2018 IPR012674 Calycin CO689_RS08340 4dc216ca8a76be13fbd3a0d3c31b6b9a 138 Gene3D G3DSA:2.40.128.20 1 138 4.3E-35 T 28-03-2018 IPR012674 Calycin CO689_RS01225 8da52bbecbf35317bf02a19edc5e1349 230 Gene3D G3DSA:1.10.442.10 48 134 4.8E-6 T 28-03-2018 CO689_RS01225 8da52bbecbf35317bf02a19edc5e1349 230 Pfam PF15807 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 64 149 6.6E-7 T 28-03-2018 IPR031627 PDZK1-interacting protein 1/SMIM24 CO689_RS07650 4c7f0653f0ac587457a82b79fee7a69a 230 Pfam PF16882 Domain of unknown function (DUF5079) 5 217 3.0E-35 T 28-03-2018 IPR031690 Protein of unknown function DUF5079 CO689_RS05020 03591f5a90e88d309fb252132591d7dc 833 Pfam PF00534 Glycosyl transferases group 1 661 808 3.1E-28 T 28-03-2018 IPR001296 Glycosyl transferase, family 1 CO689_RS05020 03591f5a90e88d309fb252132591d7dc 833 Gene3D G3DSA:3.40.50.2000 225 387 0.0012 T 28-03-2018 CO689_RS05020 03591f5a90e88d309fb252132591d7dc 833 SUPERFAMILY SSF53756 424 801 2.88E-42 T 28-03-2018 CO689_RS05020 03591f5a90e88d309fb252132591d7dc 833 Pfam PF04464 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase 44 411 2.2E-91 T 28-03-2018 IPR007554 CDP-glycerol glycerophosphotransferase GO:0016020|GO:0047355 CO689_RS05020 03591f5a90e88d309fb252132591d7dc 833 SUPERFAMILY SSF53756 162 410 2.97E-15 T 28-03-2018 CO689_RS05020 03591f5a90e88d309fb252132591d7dc 833 Gene3D G3DSA:3.40.50.2000 606 809 9.1E-29 T 28-03-2018 CO689_RS01010 09629fb013ac6f682ebbf0343ac50f8d 102 Pfam PF00085 Thioredoxin 13 98 9.1E-17 T 28-03-2018 IPR013766 Thioredoxin domain GO:0045454 CO689_RS01010 09629fb013ac6f682ebbf0343ac50f8d 102 SUPERFAMILY SSF52833 8 100 2.95E-24 T 28-03-2018 IPR012336 Thioredoxin-like fold CO689_RS01010 09629fb013ac6f682ebbf0343ac50f8d 102 Gene3D G3DSA:3.40.30.10 2 102 1.3E-21 T 28-03-2018 CO689_RS02065 99c390a47c5d5fe40f635da0c3d071e0 101 Gene3D G3DSA:1.10.10.10 32 88 1.4E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS02065 99c390a47c5d5fe40f635da0c3d071e0 101 SUPERFAMILY SSF46955 32 80 2.38E-5 T 28-03-2018 IPR009061 Putative DNA-binding domain CO689_RS02065 99c390a47c5d5fe40f635da0c3d071e0 101 Pfam PF12728 Helix-turn-helix domain 32 79 1.4E-11 T 28-03-2018 CO689_RS02065 99c390a47c5d5fe40f635da0c3d071e0 101 TIGRFAM TIGR01764 excise: DNA binding domain, excisionase family 32 79 1.5E-19 T 28-03-2018 IPR010093 SinI-like, DNA-binding domain GO:0003677 CO689_RS09075 1e797947514a9bc23cc30ecf3924dd27 353 Pfam PF00953 Glycosyl transferase family 4 73 226 3.3E-42 T 28-03-2018 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193 CO689_RS09075 1e797947514a9bc23cc30ecf3924dd27 353 ProSitePatterns PS01348 MraY family signature 2. 146 157 - T 28-03-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 CO689_RS12610 347431eebb02d11893346fb125200f08 278 Gene3D G3DSA:3.40.50.10170 1 150 2.1E-50 T 28-03-2018 CO689_RS12610 347431eebb02d11893346fb125200f08 278 TIGRFAM TIGR00762 DegV: EDD domain protein, DegV family 4 275 1.3E-92 T 28-03-2018 IPR003797 DegV CO689_RS12610 347431eebb02d11893346fb125200f08 278 SUPERFAMILY SSF82549 1 277 2.41E-86 T 28-03-2018 CO689_RS12610 347431eebb02d11893346fb125200f08 278 Gene3D G3DSA:3.30.1180.10 151 278 1.0E-28 T 28-03-2018 CO689_RS12610 347431eebb02d11893346fb125200f08 278 Pfam PF02645 Uncharacterised protein, DegV family COG1307 4 276 4.3E-82 T 28-03-2018 IPR003797 DegV CO689_RS05220 b2dc34cef1fbf49ef8aea4149ad71a3f 317 Pfam PF07859 alpha/beta hydrolase fold 82 289 2.4E-66 T 28-03-2018 IPR013094 Alpha/beta hydrolase fold-3 GO:0008152|GO:0016787 CO689_RS05220 b2dc34cef1fbf49ef8aea4149ad71a3f 317 Gene3D G3DSA:3.40.50.1820 7 317 2.4E-55 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CO689_RS05220 b2dc34cef1fbf49ef8aea4149ad71a3f 317 SUPERFAMILY SSF53474 46 313 1.85E-64 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CO689_RS12130 9e96ea6bd0d149d69e58387ce4fe02f5 325 Pfam PF00478 IMP dehydrogenase / GMP reductase domain 5 310 9.1E-69 T 28-03-2018 IPR001093 IMP dehydrogenase/GMP reductase GO:0003824|GO:0055114 CO689_RS12130 9e96ea6bd0d149d69e58387ce4fe02f5 325 PIRSF PIRSF036500 1 325 2.0E-194 T 28-03-2018 IPR005994 Guanosine monophosphate reductase, type2 GO:0003920|GO:0006163|GO:1902560 KEGG: 00230+1.7.1.7 CO689_RS12130 9e96ea6bd0d149d69e58387ce4fe02f5 325 ProSitePatterns PS00487 IMP dehydrogenase / GMP reductase signature. 164 176 - T 28-03-2018 IPR015875 IMP dehydrogenase / GMP reductase, conserved site GO:0016491|GO:0055114 CO689_RS12130 9e96ea6bd0d149d69e58387ce4fe02f5 325 SMART SM01240 2 325 2.8E-115 T 28-03-2018 CO689_RS12130 9e96ea6bd0d149d69e58387ce4fe02f5 325 TIGRFAM TIGR01306 GMP_reduct_2: guanosine monophosphate reductase 3 323 1.4E-201 T 28-03-2018 IPR005994 Guanosine monophosphate reductase, type2 GO:0003920|GO:0006163|GO:1902560 KEGG: 00230+1.7.1.7 CO689_RS12130 9e96ea6bd0d149d69e58387ce4fe02f5 325 SUPERFAMILY SSF51412 3 314 1.03E-94 T 28-03-2018 CO689_RS12130 9e96ea6bd0d149d69e58387ce4fe02f5 325 Hamap MF_01511 GMP reductase [guaC]. 1 324 64.632 T 28-03-2018 IPR005994 Guanosine monophosphate reductase, type2 GO:0003920|GO:0006163|GO:1902560 KEGG: 00230+1.7.1.7 CO689_RS12130 9e96ea6bd0d149d69e58387ce4fe02f5 325 Gene3D G3DSA:3.20.20.70 2 324 3.7E-71 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CO689_RS07165 c3018c6922e4a039cea545d5d9c05e06 195 ProSitePatterns PS00175 Phosphoglycerate mutase family phosphohistidine signature. 5 14 - T 28-03-2018 IPR001345 Phosphoglycerate/bisphosphoglycerate mutase, active site GO:0003824|GO:0008152 CO689_RS07165 c3018c6922e4a039cea545d5d9c05e06 195 Gene3D G3DSA:3.40.50.1240 1 195 6.9E-42 T 28-03-2018 IPR029033 Histidine phosphatase superfamily CO689_RS07165 c3018c6922e4a039cea545d5d9c05e06 195 SUPERFAMILY SSF53254 2 192 1.57E-42 T 28-03-2018 IPR029033 Histidine phosphatase superfamily CO689_RS07165 c3018c6922e4a039cea545d5d9c05e06 195 PIRSF PIRSF000709 2 182 1.6E-14 T 28-03-2018 CO689_RS07165 c3018c6922e4a039cea545d5d9c05e06 195 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 3 187 2.0E-33 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 CO689_RS07165 c3018c6922e4a039cea545d5d9c05e06 195 SMART SM00855 2 165 1.3E-15 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 CO689_RS00530 1ddc5384df054da4ef166790e219d2eb 95 SUPERFAMILY SSF53098 4 74 1.12E-7 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CO689_RS00530 1ddc5384df054da4ef166790e219d2eb 95 Pfam PF00665 Integrase core domain 4 74 1.3E-7 T 28-03-2018 IPR001584 Integrase, catalytic core GO:0015074 CO689_RS00530 1ddc5384df054da4ef166790e219d2eb 95 Gene3D G3DSA:3.30.420.10 1 83 2.1E-8 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CO689_RS12140 9903f0de34305704634e77f766fbf93d 326 Gene3D G3DSA:3.40.50.2300 53 170 3.2E-27 T 28-03-2018 CO689_RS12140 9903f0de34305704634e77f766fbf93d 326 SMART SM00354 1 69 3.3E-27 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CO689_RS12140 9903f0de34305704634e77f766fbf93d 326 Pfam PF00356 Bacterial regulatory proteins, lacI family 3 46 2.2E-15 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CO689_RS12140 9903f0de34305704634e77f766fbf93d 326 SUPERFAMILY SSF53822 56 311 2.16E-55 T 28-03-2018 IPR028082 Periplasmic binding protein-like I CO689_RS12140 9903f0de34305704634e77f766fbf93d 326 ProSitePatterns PS00356 LacI-type HTH domain signature. 3 21 - T 28-03-2018 CO689_RS12140 9903f0de34305704634e77f766fbf93d 326 Pfam PF13377 Periplasmic binding protein-like domain 169 305 1.7E-23 T 28-03-2018 CO689_RS12140 9903f0de34305704634e77f766fbf93d 326 Gene3D G3DSA:3.40.50.2300 171 323 7.7E-27 T 28-03-2018 CO689_RS12140 9903f0de34305704634e77f766fbf93d 326 Gene3D G3DSA:1.10.260.40 1 52 4.7E-18 T 28-03-2018 CO689_RS12140 9903f0de34305704634e77f766fbf93d 326 SUPERFAMILY SSF47413 2 57 1.65E-14 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CO689_RS08275 9d0e1cb40f985bc0623d082ccdb24abc 260 Pfam PF06738 Putative threonine/serine exporter 21 258 9.0E-57 T 28-03-2018 IPR010619 Putative threonine/serine exporter CO689_RS05370 02d34c9128cbfcedbcc7db71f14177b3 538 Pfam PF02028 BCCT, betaine/carnitine/choline family transporter 6 500 5.2E-155 T 28-03-2018 IPR000060 BCCT transporter family GO:0005215|GO:0006810|GO:0016020 CO689_RS05370 02d34c9128cbfcedbcc7db71f14177b3 538 TIGRFAM TIGR00842 bcct: transporter, betaine/carnitine/choline transporter (BCCT) family 45 501 5.9E-143 T 28-03-2018 IPR000060 BCCT transporter family GO:0005215|GO:0006810|GO:0016020 CO689_RS04515 2ff755f0097874cda176ed59766d7ef7 341 Pfam PF13303 Phosphotransferase system, EIIC 11 330 2.8E-103 T 28-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 CO689_RS04005 1f0e21a338bf948c4ccef146ae59ab77 156 SUPERFAMILY SSF55961 4 155 5.5E-33 T 28-03-2018 CO689_RS04005 1f0e21a338bf948c4ccef146ae59ab77 156 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 17 155 8.0E-21 T 28-03-2018 IPR013538 Activator of Hsp90 ATPase homologue 1-like GO:0006950 CO689_RS04005 1f0e21a338bf948c4ccef146ae59ab77 156 Gene3D G3DSA:3.30.530.20 1 156 7.7E-20 T 28-03-2018 IPR023393 START-like domain CO689_RS05215 1b030adb946c496688e8b18299295553 101 SMART SM00418 14 93 8.7E-15 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CO689_RS05215 1b030adb946c496688e8b18299295553 101 Pfam PF01022 Bacterial regulatory protein, arsR family 22 67 1.0E-12 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CO689_RS05215 1b030adb946c496688e8b18299295553 101 Gene3D G3DSA:1.10.10.10 2 92 1.8E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS05215 1b030adb946c496688e8b18299295553 101 SUPERFAMILY SSF46785 10 93 1.26E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS05215 1b030adb946c496688e8b18299295553 101 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 16 31 1.4E-8 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CO689_RS05215 1b030adb946c496688e8b18299295553 101 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 49 64 1.4E-8 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CO689_RS05215 1b030adb946c496688e8b18299295553 101 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 64 79 1.4E-8 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CO689_RS13645 1bf838124cdee9ab08f5a481a781f2fa 361 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 31 85 1.0E-4 T 28-03-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 CO689_RS13645 1bf838124cdee9ab08f5a481a781f2fa 361 Pfam PF00589 Phage integrase family 167 343 4.4E-45 T 28-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 CO689_RS13645 1bf838124cdee9ab08f5a481a781f2fa 361 Gene3D G3DSA:1.10.443.10 163 345 2.3E-41 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 CO689_RS13645 1bf838124cdee9ab08f5a481a781f2fa 361 SUPERFAMILY SSF56349 31 350 3.83E-48 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CO689_RS13645 1bf838124cdee9ab08f5a481a781f2fa 361 Gene3D G3DSA:1.10.150.130 19 131 7.1E-15 T 28-03-2018 IPR023109 Integrase/recombinase, N-terminal CO689_RS09180 e23f7df0eeb9b6f7504b18b34955e96c 394 Pfam PF07690 Major Facilitator Superfamily 16 238 1.5E-34 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CO689_RS09180 e23f7df0eeb9b6f7504b18b34955e96c 394 SUPERFAMILY SSF103473 6 388 9.02E-65 T 28-03-2018 IPR020846 Major facilitator superfamily domain CO689_RS09180 e23f7df0eeb9b6f7504b18b34955e96c 394 Gene3D G3DSA:1.20.1250.20 5 196 6.4E-35 T 28-03-2018 CO689_RS09180 e23f7df0eeb9b6f7504b18b34955e96c 394 Gene3D G3DSA:1.20.1250.20 197 392 1.8E-22 T 28-03-2018 CO689_RS08980 79029c3caa61bf2ad023a2d96283059a 295 SUPERFAMILY SSF103481 40 140 5.89E-13 T 28-03-2018 CO689_RS08980 79029c3caa61bf2ad023a2d96283059a 295 Pfam PF00892 EamA-like transporter family 146 275 5.5E-11 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CO689_RS08980 79029c3caa61bf2ad023a2d96283059a 295 Pfam PF00892 EamA-like transporter family 6 137 9.7E-10 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CO689_RS08980 79029c3caa61bf2ad023a2d96283059a 295 SUPERFAMILY SSF103481 180 276 3.92E-14 T 28-03-2018 CO689_RS10000 c94fc392e96006b7145df9a2efd0e680 116 Pfam PF00420 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L 5 107 5.9E-30 T 28-03-2018 CO689_RS07380 9fcb5e0f26d0b5ee886dc02bb14d3a6f 205 Pfam PF01810 LysE type translocator 15 196 2.3E-28 T 28-03-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 CO689_RS10645 f565901c328f19dc377ae526d5690f26 171 SUPERFAMILY SSF89623 1 134 5.23E-44 T 28-03-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 CO689_RS10645 f565901c328f19dc377ae526d5690f26 171 Gene3D G3DSA:3.40.1400.10 1 170 5.1E-50 T 28-03-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 CO689_RS10645 f565901c328f19dc377ae526d5690f26 171 PIRSF PIRSF005384 1 146 5.0E-44 T 28-03-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 CO689_RS10645 f565901c328f19dc377ae526d5690f26 171 Pfam PF02502 Ribose/Galactose Isomerase 3 139 3.4E-39 T 28-03-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 CO689_RS10645 f565901c328f19dc377ae526d5690f26 171 TIGRFAM TIGR00689 rpiB_lacA_lacB: sugar-phosphate isomerase, RpiB/LacA/LacB family 3 131 1.1E-33 T 28-03-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 CO689_RS10775 8dcaa4df72624c42fda030c928be4264 264 Pfam PF02361 Cobalt transport protein 18 218 2.9E-22 T 28-03-2018 IPR003339 ABC/ECF transporter, transmembrane component CO689_RS04310 90b7cdcce26304506f4c1cbc79146305 467 Pfam PF13347 MFS/sugar transport protein 13 437 4.4E-85 T 28-03-2018 CO689_RS04310 90b7cdcce26304506f4c1cbc79146305 467 SUPERFAMILY SSF103473 11 429 1.83E-31 T 28-03-2018 IPR020846 Major facilitator superfamily domain CO689_RS04310 90b7cdcce26304506f4c1cbc79146305 467 TIGRFAM TIGR00792 gph: sugar (Glycoside-Pentoside-Hexuronide) transporter 11 450 4.8E-135 T 28-03-2018 IPR001927 Sodium:galactoside symporter GO:0005215|GO:0006814|GO:0016020 CO689_RS04310 90b7cdcce26304506f4c1cbc79146305 467 Gene3D G3DSA:1.20.1250.20 221 434 1.4E-11 T 28-03-2018 CO689_RS04310 90b7cdcce26304506f4c1cbc79146305 467 Gene3D G3DSA:1.20.1250.20 11 220 9.1E-13 T 28-03-2018 CO689_RS04310 90b7cdcce26304506f4c1cbc79146305 467 ProSitePatterns PS00872 Sodium:galactoside symporter family signature. 61 86 - T 28-03-2018 IPR018043 Sodium:galactoside symporter, conserved site GO:0005215|GO:0006814|GO:0016020 CO689_RS06565 762f6b3e947a85088ef04384fd374724 733 Pfam PF05257 CHAP domain 617 705 7.8E-18 T 28-03-2018 IPR007921 CHAP domain CO689_RS06565 762f6b3e947a85088ef04384fd374724 733 SMART SM00047 428 587 1.1E-41 T 28-03-2018 IPR002901 Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain GO:0004040 CO689_RS06565 762f6b3e947a85088ef04384fd374724 733 SUPERFAMILY SSF54001 620 708 5.2E-18 T 28-03-2018 CO689_RS06565 762f6b3e947a85088ef04384fd374724 733 Gene3D G3DSA:1.10.530.10 432 587 5.8E-34 T 28-03-2018 CO689_RS06565 762f6b3e947a85088ef04384fd374724 733 Pfam PF01832 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase 445 582 8.3E-19 T 28-03-2018 IPR002901 Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain GO:0004040 CO689_RS00460 efb93ea3b7605af5a0c4f6dc6310894a 534 Pfam PF02652 L-lactate permease 14 528 2.5E-151 T 28-03-2018 IPR003804 L-lactate permease GO:0005887|GO:0015129|GO:0015727 CO689_RS00460 efb93ea3b7605af5a0c4f6dc6310894a 534 TIGRFAM TIGR00795 lctP: transporter, lactate permease (LctP) family 13 529 1.2E-151 T 28-03-2018 IPR003804 L-lactate permease GO:0005887|GO:0015129|GO:0015727 CO689_RS03890 b6eae885cde3c7fbd95c13ef836ad3a5 118 Pfam PF11337 Protein of unknown function (DUF3139) 4 81 6.1E-20 T 28-03-2018 IPR021486 Protein of unknown function DUF3139 CO689_RS03545 492b4dbb0515274140680583a7614478 238 Pfam PF02517 CAAX protease self-immunity 136 229 1.3E-14 T 28-03-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 CO689_RS00165 98ad2309b2694309bcd4dbf83219afd0 82 Gene3D G3DSA:2.10.260.10 1 82 2.7E-11 T 28-03-2018 CO689_RS00165 98ad2309b2694309bcd4dbf83219afd0 82 SUPERFAMILY SSF89447 5 56 1.27E-7 T 28-03-2018 CO689_RS00030 98ad2309b2694309bcd4dbf83219afd0 82 Gene3D G3DSA:2.10.260.10 1 82 2.7E-11 T 28-03-2018 CO689_RS00030 98ad2309b2694309bcd4dbf83219afd0 82 SUPERFAMILY SSF89447 5 56 1.27E-7 T 28-03-2018 CO689_RS09150 cd9b82fc19aa8c4c17ade67c2c6a5df4 160 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 117 145 - T 28-03-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 CO689_RS09150 cd9b82fc19aa8c4c17ade67c2c6a5df4 160 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 80 94 0.097 T 28-03-2018 IPR001451 Hexapeptide repeat CO689_RS09150 cd9b82fc19aa8c4c17ade67c2c6a5df4 160 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 109 143 1.0E-10 T 28-03-2018 IPR001451 Hexapeptide repeat CO689_RS09150 cd9b82fc19aa8c4c17ade67c2c6a5df4 160 SUPERFAMILY SSF51161 42 158 4.3E-31 T 28-03-2018 IPR011004 Trimeric LpxA-like CO689_RS09150 cd9b82fc19aa8c4c17ade67c2c6a5df4 160 Gene3D G3DSA:2.160.10.10 19 159 3.1E-27 T 28-03-2018 CO689_RS08245 ce26ec9b5ec2e1a82a39e694573f89b1 125 Pfam PF17261 Family of unknown function (DUF5327) 3 125 2.6E-12 T 28-03-2018 IPR035218 Protein of unknown function DUF5327 CO689_RS08735 ec456d2704f8446f66bf7799ff0c7d76 233 Gene3D G3DSA:1.20.120.20 33 97 5.4E-5 T 28-03-2018 CO689_RS12275 89d1ec39b3078634e70628933637004d 841 Pfam PF09924 Uncharacterised conserved protein (DUF2156) 528 820 1.7E-79 T 28-03-2018 IPR024320 Phosphatidylglycerol lysyltransferase, C-terminal CO689_RS12275 89d1ec39b3078634e70628933637004d 841 Pfam PF03706 Lysylphosphatidylglycerol synthase TM region 17 289 6.6E-11 T 28-03-2018 IPR022791 Lysylphosphatidylglycerol synthetase/glycosyltransferase AglD CO689_RS12275 89d1ec39b3078634e70628933637004d 841 SUPERFAMILY SSF55729 639 821 5.83E-14 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CO689_RS12275 89d1ec39b3078634e70628933637004d 841 Gene3D G3DSA:3.40.630.30 630 813 1.3E-16 T 28-03-2018 CO689_RS10850 72b3d7cf01cbc78a1742c61f1d36543e 186 SUPERFAMILY SSF56420 2 180 3.93E-59 T 28-03-2018 IPR023635 Peptide deformylase CO689_RS10850 72b3d7cf01cbc78a1742c61f1d36543e 186 TIGRFAM TIGR00079 pept_deformyl: peptide deformylase 4 180 5.3E-48 T 28-03-2018 IPR023635 Peptide deformylase CO689_RS10850 72b3d7cf01cbc78a1742c61f1d36543e 186 PRINTS PR01576 Peptide deformylase signature 141 170 2.9E-30 T 28-03-2018 IPR023635 Peptide deformylase CO689_RS10850 72b3d7cf01cbc78a1742c61f1d36543e 186 PRINTS PR01576 Peptide deformylase signature 122 140 2.9E-30 T 28-03-2018 IPR023635 Peptide deformylase CO689_RS10850 72b3d7cf01cbc78a1742c61f1d36543e 186 PRINTS PR01576 Peptide deformylase signature 47 76 2.9E-30 T 28-03-2018 IPR023635 Peptide deformylase CO689_RS10850 72b3d7cf01cbc78a1742c61f1d36543e 186 PRINTS PR01576 Peptide deformylase signature 109 120 2.9E-30 T 28-03-2018 IPR023635 Peptide deformylase CO689_RS10850 72b3d7cf01cbc78a1742c61f1d36543e 186 Hamap MF_00163 Peptide deformylase [def]. 3 183 28.275 T 28-03-2018 IPR023635 Peptide deformylase CO689_RS10850 72b3d7cf01cbc78a1742c61f1d36543e 186 Gene3D G3DSA:3.90.45.10 3 184 7.2E-54 T 28-03-2018 IPR023635 Peptide deformylase CO689_RS10850 72b3d7cf01cbc78a1742c61f1d36543e 186 PIRSF PIRSF004749 1 183 1.1E-46 T 28-03-2018 IPR023635 Peptide deformylase CO689_RS10850 72b3d7cf01cbc78a1742c61f1d36543e 186 Pfam PF01327 Polypeptide deformylase 4 172 3.8E-45 T 28-03-2018 IPR023635 Peptide deformylase CO689_RS11040 a20d1242ae99ce158236891854300e36 57 Pfam PF01783 Ribosomal L32p protein family 2 57 1.7E-28 T 28-03-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CO689_RS11040 a20d1242ae99ce158236891854300e36 57 Gene3D G3DSA:2.20.28.10 35 57 0.009 T 28-03-2018 CO689_RS11040 a20d1242ae99ce158236891854300e36 57 SUPERFAMILY SSF57829 1 55 2.26E-24 T 28-03-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 CO689_RS11040 a20d1242ae99ce158236891854300e36 57 TIGRFAM TIGR01031 rpmF_bact: ribosomal protein bL32 2 55 1.7E-29 T 28-03-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CO689_RS11040 a20d1242ae99ce158236891854300e36 57 Hamap MF_00340 50S ribosomal protein L32 [rpmF]. 1 55 21.188 T 28-03-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CO689_RS08535 b4c2dd989a3e98a906249138de62741c 338 SUPERFAMILY SSF81345 5 334 1.57E-80 T 28-03-2018 IPR029022 ABC transporter, BtuC-like CO689_RS08535 b4c2dd989a3e98a906249138de62741c 338 Pfam PF01032 FecCD transport family 20 334 3.1E-88 T 28-03-2018 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 CO689_RS08535 b4c2dd989a3e98a906249138de62741c 338 Gene3D G3DSA:1.10.3470.10 5 338 9.2E-68 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CO689_RS01390 c9e25fad0802a0f796bc48f991382ef8 154 SUPERFAMILY SSF47413 10 62 8.85E-10 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CO689_RS01390 c9e25fad0802a0f796bc48f991382ef8 154 SMART SM00530 13 67 9.5E-4 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CO689_RS01390 c9e25fad0802a0f796bc48f991382ef8 154 Pfam PF01381 Helix-turn-helix 15 61 3.2E-5 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CO689_RS01390 c9e25fad0802a0f796bc48f991382ef8 154 Gene3D G3DSA:1.10.260.40 9 132 1.6E-10 T 28-03-2018 CO689_RS12285 a94f5c055b1bcc76d7ea73dd03ae5cd3 304 Gene3D G3DSA:3.40.50.880 27 292 4.9E-30 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CO689_RS12285 a94f5c055b1bcc76d7ea73dd03ae5cd3 304 SUPERFAMILY SSF52317 29 284 1.33E-58 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CO689_RS12285 a94f5c055b1bcc76d7ea73dd03ae5cd3 304 PIRSF PIRSF000450 3 297 1.3E-77 T 28-03-2018 IPR033752 MetA family KEGG: 00270+2.3.1.46|KEGG: 00920+2.3.1.46 CO689_RS12285 a94f5c055b1bcc76d7ea73dd03ae5cd3 304 ProDom PD037892 HOMOSERINE O-SUCCINYLTRANSFERASE TRANSFERASE ACYLTRANSFERASE BIOSYNTHESIS TRANSSUCCINYLASE HTS METHIONINE O- AMINO-ACID 29 280 8.0E-51 T 28-03-2018 CO689_RS12285 a94f5c055b1bcc76d7ea73dd03ae5cd3 304 Pfam PF04204 Homoserine O-succinyltransferase 27 284 3.5E-77 T 28-03-2018 IPR033752 MetA family KEGG: 00270+2.3.1.46|KEGG: 00920+2.3.1.46 CO689_RS12300 140f915a94e55463d1c03702ad0b36b0 61 Gene3D G3DSA:3.30.429.10 1 61 2.7E-19 T 28-03-2018 CO689_RS12300 140f915a94e55463d1c03702ad0b36b0 61 Pfam PF01361 Tautomerase enzyme 2 60 1.9E-23 T 28-03-2018 IPR004370 4-oxalocrotonate tautomerase GO:0006725|GO:0016853 CO689_RS12300 140f915a94e55463d1c03702ad0b36b0 61 TIGRFAM TIGR00013 taut: 4-oxalocrotonate tautomerase family enzyme 1 59 2.8E-21 T 28-03-2018 IPR018191 4-oxalocrotonate tautomerase, Pseudomonas-type GO:0006725|GO:0016853 CO689_RS12300 140f915a94e55463d1c03702ad0b36b0 61 SUPERFAMILY SSF55331 2 60 4.45E-18 T 28-03-2018 IPR014347 Tautomerase/MIF superfamily CO689_RS01780 9556a0a45f8f654aa48920bc494aef9f 306 SMART SM00046 4 132 5.0E-11 T 28-03-2018 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 CO689_RS01780 9556a0a45f8f654aa48920bc494aef9f 306 TIGRFAM TIGR00147 TIGR00147: lipid kinase, YegS/Rv2252/BmrU family 3 295 1.1E-93 T 28-03-2018 IPR005218 Diacylglycerol/lipid kinase CO689_RS01780 9556a0a45f8f654aa48920bc494aef9f 306 Pfam PF00781 Diacylglycerol kinase catalytic domain 5 128 3.6E-35 T 28-03-2018 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 CO689_RS01780 9556a0a45f8f654aa48920bc494aef9f 306 Gene3D G3DSA:3.40.50.10330 1 132 9.5E-35 T 28-03-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, domain 1 GO:0003951|GO:0008152 CO689_RS01780 9556a0a45f8f654aa48920bc494aef9f 306 SUPERFAMILY SSF111331 1 298 7.46E-82 T 28-03-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain CO689_RS06790 afd28bbdd0cf2d27c860a95a388357f2 108 SUPERFAMILY SSF46785 14 107 1.82E-25 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS06790 afd28bbdd0cf2d27c860a95a388357f2 108 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 59 74 1.8E-12 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CO689_RS06790 afd28bbdd0cf2d27c860a95a388357f2 108 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 74 89 1.8E-12 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CO689_RS06790 afd28bbdd0cf2d27c860a95a388357f2 108 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 27 42 1.8E-12 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CO689_RS06790 afd28bbdd0cf2d27c860a95a388357f2 108 Gene3D G3DSA:1.10.10.10 1 108 1.3E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS06790 afd28bbdd0cf2d27c860a95a388357f2 108 Pfam PF01022 Bacterial regulatory protein, arsR family 32 77 2.1E-14 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CO689_RS06790 afd28bbdd0cf2d27c860a95a388357f2 108 SMART SM00418 25 103 8.0E-29 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CO689_RS09195 9ef30ee7aeb152d9f02e40dc6279bf17 351 Gene3D G3DSA:1.10.443.10 167 336 2.7E-36 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 CO689_RS09195 9ef30ee7aeb152d9f02e40dc6279bf17 351 Pfam PF00589 Phage integrase family 170 333 2.8E-24 T 28-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 CO689_RS09195 9ef30ee7aeb152d9f02e40dc6279bf17 351 Pfam PF14657 Arm DNA-binding domain 12 53 1.0E-10 T 28-03-2018 IPR028259 AP2-like integrase, N-terminal domain CO689_RS09195 9ef30ee7aeb152d9f02e40dc6279bf17 351 Gene3D G3DSA:1.10.150.130 58 166 6.5E-15 T 28-03-2018 IPR023109 Integrase/recombinase, N-terminal CO689_RS09195 9ef30ee7aeb152d9f02e40dc6279bf17 351 Pfam PF14659 Phage integrase, N-terminal SAM-like domain 63 117 1.8E-10 T 28-03-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 CO689_RS09195 9ef30ee7aeb152d9f02e40dc6279bf17 351 SUPERFAMILY SSF56349 63 339 1.0E-61 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CO689_RS02960 27e82c6a8ad702ca44830d62567582d4 292 Pfam PF02517 CAAX protease self-immunity 182 277 5.3E-14 T 28-03-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 CO689_RS08135 7cfb8f2418b66df0e07257467f041d86 239 Gene3D G3DSA:3.40.50.1000 1 235 3.3E-30 T 28-03-2018 IPR023214 HAD-like domain CO689_RS08135 7cfb8f2418b66df0e07257467f041d86 239 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 147 163 3.1E-7 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CO689_RS08135 7cfb8f2418b66df0e07257467f041d86 239 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 3 14 3.1E-7 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CO689_RS08135 7cfb8f2418b66df0e07257467f041d86 239 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 116 129 3.1E-7 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CO689_RS08135 7cfb8f2418b66df0e07257467f041d86 239 Pfam PF13419 Haloacid dehalogenase-like hydrolase 6 199 1.6E-27 T 28-03-2018 IPR023214 HAD-like domain CO689_RS08135 7cfb8f2418b66df0e07257467f041d86 239 SUPERFAMILY SSF56784 1 233 6.3E-42 T 28-03-2018 IPR023214 HAD-like domain CO689_RS08135 7cfb8f2418b66df0e07257467f041d86 239 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 104 198 3.0E-8 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CO689_RS01925 a1519e1f9765b628ab053019b7da4b48 278 Pfam PF13349 Putative adhesin 45 277 8.6E-23 T 28-03-2018 IPR025164 Putative adhesin CO689_RS08385 e18e5e8833e41360da3d9f52597eab8c 307 Pfam PF13437 HlyD family secretion protein 147 231 2.5E-5 T 28-03-2018 CO689_RS02560 45ac2c308d346f4a1e2aef279b23757b 177 Pfam PF10740 Domain of unknown function (DUF2529) 1 168 1.1E-59 T 28-03-2018 IPR019676 Domain of unknown function (DUF2529) CO689_RS05090 e43a7b558aa8d176d7fa5e18a90ea00d 457 Pfam PF00324 Amino acid permease 14 444 3.3E-110 T 28-03-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0006810|GO:0016020|GO:0055085 CO689_RS05090 e43a7b558aa8d176d7fa5e18a90ea00d 457 PIRSF PIRSF006060 1 454 2.6E-70 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CO689_RS00020 71ba2d409e08d70ff52944d24d6a1777 239 SUPERFAMILY SSF50494 72 188 2.31E-14 T 28-03-2018 IPR009003 Peptidase S1, PA clan CO689_RS00020 71ba2d409e08d70ff52944d24d6a1777 239 Pfam PF13365 Trypsin-like peptidase domain 83 190 4.2E-6 T 28-03-2018 CO689_RS00020 71ba2d409e08d70ff52944d24d6a1777 239 Gene3D G3DSA:2.40.10.10 26 187 1.2E-8 T 28-03-2018 CO689_RS03530 df0de2fa87043ae761ebb3eeace8e05c 308 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 82 226 6.2E-46 T 28-03-2018 IPR004474 Cell envelope-related transcriptional attenuator domain CO689_RS03530 df0de2fa87043ae761ebb3eeace8e05c 308 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 82 227 3.5E-46 T 28-03-2018 IPR004474 Cell envelope-related transcriptional attenuator domain CO689_RS10435 d9007e2336ff980dea75649bf750dac6 485 SUPERFAMILY SSF158911 32 152 1.83E-31 T 28-03-2018 CO689_RS10435 d9007e2336ff980dea75649bf750dac6 485 SUPERFAMILY SSF158911 189 316 6.02E-37 T 28-03-2018 CO689_RS10435 d9007e2336ff980dea75649bf750dac6 485 SMART SM00725 199 320 9.2E-34 T 28-03-2018 IPR006635 NEAT domain CO689_RS10435 d9007e2336ff980dea75649bf750dac6 485 SMART SM00725 35 154 1.6E-28 T 28-03-2018 IPR006635 NEAT domain CO689_RS10435 d9007e2336ff980dea75649bf750dac6 485 Pfam PF05031 Iron Transport-associated domain 40 146 5.8E-23 T 28-03-2018 IPR006635 NEAT domain CO689_RS10435 d9007e2336ff980dea75649bf750dac6 485 Pfam PF05031 Iron Transport-associated domain 203 313 4.4E-27 T 28-03-2018 IPR006635 NEAT domain CO689_RS07220 cb220caf91bd71a82578b356dd995d29 323 Gene3D G3DSA:1.10.1660.10 1 170 3.4E-4 T 28-03-2018 CO689_RS04455 08ca168b4c7d8f41bd8f747475167aa4 205 Pfam PF04893 Yip1 domain 11 194 1.2E-10 T 28-03-2018 IPR006977 Yip1 domain GO:0016020 CO689_RS08860 91bd232c24a0023d917cb491f471e62f 231 Gene3D G3DSA:1.20.120.520 64 231 1.0E-22 T 28-03-2018 CO689_RS08860 91bd232c24a0023d917cb491f471e62f 231 Gene3D G3DSA:1.10.3910.10 1 63 9.4E-16 T 28-03-2018 CO689_RS08860 91bd232c24a0023d917cb491f471e62f 231 Pfam PF01814 Hemerythrin HHE cation binding domain 82 223 2.1E-18 T 28-03-2018 IPR012312 Haemerythrin-like Reactome: R-HSA-390471|Reactome: R-HSA-8951664|Reactome: R-HSA-917937|Reactome: R-HSA-983168 CO689_RS08860 91bd232c24a0023d917cb491f471e62f 231 Hamap MF_01156 Iron-sulfur cluster repair protein ScdA [scdA]. 1 225 50.617 T 28-03-2018 IPR023551 Iron-sulfur cluster repair protein ScdA GO:0006979 CO689_RS08860 91bd232c24a0023d917cb491f471e62f 231 Pfam PF04405 Domain of Unknown function (DUF542) 6 59 7.4E-18 T 28-03-2018 IPR019903 Repair of iron centres family CO689_RS08860 91bd232c24a0023d917cb491f471e62f 231 TIGRFAM TIGR03652 FeS_repair_RIC: iron-sulfur cluster repair di-iron protein 8 223 2.9E-72 T 28-03-2018 IPR019903 Repair of iron centres family CO689_RS04065 397220b5d04c2eafb8c7603be9f465ba 126 Pfam PF04138 GtrA-like protein 12 123 3.4E-23 T 28-03-2018 IPR007267 GtrA-like protein GO:0000271|GO:0006810|GO:0016021 CO689_RS07030 f05bac1df87f819c12367766cb9808ed 45 Pfam PF00468 Ribosomal protein L34 3 45 7.8E-23 T 28-03-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CO689_RS07030 f05bac1df87f819c12367766cb9808ed 45 TIGRFAM TIGR01030 rpmH_bact: ribosomal protein bL34 3 45 7.9E-20 T 28-03-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CO689_RS07030 f05bac1df87f819c12367766cb9808ed 45 Hamap MF_00391 50S ribosomal protein L34 [rpmH]. 2 45 15.729 T 28-03-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CO689_RS07030 f05bac1df87f819c12367766cb9808ed 45 ProSitePatterns PS00784 Ribosomal protein L34 signature. 3 22 - T 28-03-2018 IPR020939 Ribosomal protein L34, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CO689_RS07030 f05bac1df87f819c12367766cb9808ed 45 ProDom PD003101 RIBOSOMAL L34 RIBONUCLEOPROTEIN 50S CHLOROPLAST PLASTID L34 MITOCHONDRIAL PEPTIDE SEQUENCING 3 27 2.0E-7 T 28-03-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CO689_RS00245 b39ce9ddb583b08678f060f9e19718d1 459 PIRSF PIRSF006304 4 459 1.5E-122 T 28-03-2018 IPR013853 Galactitol permease IIC component GO:0015577|GO:0015796 CO689_RS00245 b39ce9ddb583b08678f060f9e19718d1 459 Pfam PF03611 PTS system sugar-specific permease component 14 385 2.0E-37 T 28-03-2018 IPR004703 Phosphotransferase system, sugar-specific permease component GO:0009401|GO:0016021 CO689_RS06115 62ab420e060dc22a41f90a05c83a989c 303 Pfam PF01939 Endonuclease NucS 24 104 5.8E-5 T 28-03-2018 IPR002793 Endonuclease NucS CO689_RS08580 3690ce7e4b16de614da9d50e79b12690 205 Gene3D G3DSA:1.20.58.220 99 204 1.4E-6 T 28-03-2018 CO689_RS08580 3690ce7e4b16de614da9d50e79b12690 205 SUPERFAMILY SSF109755 20 195 1.96E-5 T 28-03-2018 CO689_RS08580 3690ce7e4b16de614da9d50e79b12690 205 Pfam PF01865 Protein of unknown function DUF47 2 202 1.4E-21 T 28-03-2018 IPR018445 Putative phosphate transport regulator CO689_RS03665 99610929ab94b99606d5be945092421c 338 Gene3D G3DSA:2.70.98.10 2 335 1.2E-62 T 28-03-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 CO689_RS03665 99610929ab94b99606d5be945092421c 338 ProSitePatterns PS00545 Aldose 1-epimerase putative active site. 168 177 - T 28-03-2018 IPR018052 Aldose 1-epimerase, conserved site KEGG: 00010+5.1.3.3|KEGG: 00052+5.1.3.3|MetaCyc: PWY-6317 CO689_RS03665 99610929ab94b99606d5be945092421c 338 SUPERFAMILY SSF74650 3 333 2.95E-71 T 28-03-2018 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 CO689_RS03665 99610929ab94b99606d5be945092421c 338 Pfam PF01263 Aldose 1-epimerase 13 332 2.3E-51 T 28-03-2018 IPR008183 Aldose 1-/Glucose-6-phosphate 1-epimerase GO:0005975|GO:0016853 CO689_RS05545 0a51f23f3df516ff2cd6b00fba7fda00 307 SUPERFAMILY SSF53850 32 303 2.64E-66 T 28-03-2018 CO689_RS05545 0a51f23f3df516ff2cd6b00fba7fda00 307 Pfam PF04069 Substrate binding domain of ABC-type glycine betaine transport system 32 300 6.8E-54 T 28-03-2018 IPR007210 ABC-type glycine betaine transport system, substrate-binding domain GO:0005215|GO:0006810 CO689_RS05545 0a51f23f3df516ff2cd6b00fba7fda00 307 Gene3D G3DSA:3.40.190.10 179 304 8.5E-24 T 28-03-2018 CO689_RS05545 0a51f23f3df516ff2cd6b00fba7fda00 307 Gene3D G3DSA:3.40.190.10 21 178 6.6E-26 T 28-03-2018 CO689_RS09115 d1e3708b6e3b7c7639609254385ec149 311 SUPERFAMILY SSF54001 195 310 1.47E-18 T 28-03-2018 CO689_RS09115 d1e3708b6e3b7c7639609254385ec149 311 SUPERFAMILY SSF54106 74 116 1.96E-8 T 28-03-2018 IPR018392 LysM domain CO689_RS09115 d1e3708b6e3b7c7639609254385ec149 311 Gene3D G3DSA:3.10.350.10 20 68 1.8E-4 T 28-03-2018 CO689_RS09115 d1e3708b6e3b7c7639609254385ec149 311 SMART SM00257 27 70 0.15 T 28-03-2018 IPR018392 LysM domain CO689_RS09115 d1e3708b6e3b7c7639609254385ec149 311 SMART SM00257 74 117 1.9E-4 T 28-03-2018 IPR018392 LysM domain CO689_RS09115 d1e3708b6e3b7c7639609254385ec149 311 Pfam PF05257 CHAP domain 210 286 7.7E-13 T 28-03-2018 IPR007921 CHAP domain CO689_RS09115 d1e3708b6e3b7c7639609254385ec149 311 Pfam PF01476 LysM domain 28 62 0.058 T 28-03-2018 IPR018392 LysM domain CO689_RS09115 d1e3708b6e3b7c7639609254385ec149 311 Pfam PF01476 LysM domain 76 114 2.7E-7 T 28-03-2018 IPR018392 LysM domain CO689_RS09115 d1e3708b6e3b7c7639609254385ec149 311 Gene3D G3DSA:3.10.350.10 69 202 2.5E-12 T 28-03-2018 CO689_RS04495 5b8bffdc41f19b3c943dba24a33579e8 208 SUPERFAMILY SSF52218 1 208 1.12E-49 T 28-03-2018 IPR029039 Flavoprotein-like domain CO689_RS04495 5b8bffdc41f19b3c943dba24a33579e8 208 Gene3D G3DSA:3.40.50.360 3 208 1.1E-36 T 28-03-2018 IPR029039 Flavoprotein-like domain CO689_RS04495 5b8bffdc41f19b3c943dba24a33579e8 208 Pfam PF02525 Flavodoxin-like fold 3 202 1.8E-42 T 28-03-2018 IPR003680 Flavodoxin-like fold CO689_RS04495 5b8bffdc41f19b3c943dba24a33579e8 208 Hamap MF_01216 FMN-dependent NADH-azoreductase [azoR]. 2 208 28.735 T 28-03-2018 IPR023048 NADH-azoreductase, FMN-dependent GO:0016661|GO:0055114 CO689_RS10135 b7e10a0d997610fd6b70266495e826ce 617 Gene3D G3DSA:3.40.50.1110 408 610 4.0E-16 T 28-03-2018 CO689_RS10135 b7e10a0d997610fd6b70266495e826ce 617 Pfam PF01757 Acyltransferase family 25 356 5.8E-30 T 28-03-2018 IPR002656 Acyltransferase 3 GO:0016747 CO689_RS10135 b7e10a0d997610fd6b70266495e826ce 617 SUPERFAMILY SSF52266 456 609 3.5E-16 T 28-03-2018 IPR013830 SGNH hydrolase-type esterase domain CO689_RS05955 f0c1f7f71b04dbc1d2963bbad56505ce 93 Gene3D G3DSA:3.40.630.30 2 93 7.5E-18 T 28-03-2018 CO689_RS05955 f0c1f7f71b04dbc1d2963bbad56505ce 93 Pfam PF14542 GCN5-related N-acetyl-transferase 11 89 7.1E-24 T 28-03-2018 IPR031165 Yjdj-type Gcn5-related N-acetyltransferase CO689_RS05955 f0c1f7f71b04dbc1d2963bbad56505ce 93 SUPERFAMILY SSF55729 3 90 8.51E-26 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CO689_RS09205 0591a3b0cd0df46b2abac3722d16d3fa 75 SUPERFAMILY SSF47413 14 74 3.85E-9 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CO689_RS09205 0591a3b0cd0df46b2abac3722d16d3fa 75 Gene3D G3DSA:1.10.260.40 13 75 1.2E-8 T 28-03-2018 CO689_RS08460 9179f70ceec485070d1a6a0f8d0bc7ed 401 Pfam PF07690 Major Facilitator Superfamily 8 344 2.5E-16 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CO689_RS08460 9179f70ceec485070d1a6a0f8d0bc7ed 401 Gene3D G3DSA:1.20.1250.20 1 187 1.9E-12 T 28-03-2018 CO689_RS08460 9179f70ceec485070d1a6a0f8d0bc7ed 401 SUPERFAMILY SSF103473 2 386 2.35E-26 T 28-03-2018 IPR020846 Major facilitator superfamily domain CO689_RS08460 9179f70ceec485070d1a6a0f8d0bc7ed 401 Gene3D G3DSA:1.20.1250.20 188 387 1.7E-10 T 28-03-2018 CO689_RS09915 13d8a9c03a24280713207f1c0702b952 78 SUPERFAMILY SSF47336 2 76 1.44E-13 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CO689_RS09915 13d8a9c03a24280713207f1c0702b952 78 Pfam PF00550 Phosphopantetheine attachment site 5 74 7.9E-9 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CO689_RS09915 13d8a9c03a24280713207f1c0702b952 78 TIGRFAM TIGR01688 dltC: D-alanine--poly(phosphoribitol) ligase, subunit 2 4 76 1.1E-41 T 28-03-2018 IPR003230 D-alanine--poly(phosphoribitol) ligase subunit 2 GO:0019350|GO:0036370 KEGG: 00473+6.1.1.13 CO689_RS09915 13d8a9c03a24280713207f1c0702b952 78 Hamap MF_00565 D-alanine--poly(phosphoribitol) ligase subunit 2 [dltC]. 1 78 47.198 T 28-03-2018 IPR003230 D-alanine--poly(phosphoribitol) ligase subunit 2 GO:0019350|GO:0036370 KEGG: 00473+6.1.1.13 CO689_RS09915 13d8a9c03a24280713207f1c0702b952 78 Gene3D G3DSA:1.10.1200.10 1 78 2.6E-10 T 28-03-2018 CO689_RS12540 40000c8f5fdbfce388bc690c136db100 271 SUPERFAMILY SSF54593 3 121 6.8E-13 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CO689_RS12540 40000c8f5fdbfce388bc690c136db100 271 Gene3D G3DSA:3.10.180.10 141 259 0.0027 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CO689_RS12540 40000c8f5fdbfce388bc690c136db100 271 Gene3D G3DSA:3.10.180.10 1 127 4.6E-8 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CO689_RS12540 40000c8f5fdbfce388bc690c136db100 271 SUPERFAMILY SSF54593 143 244 8.45E-5 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CO689_RS01440 a3a8bb716e3c2fb9ba01d7f9eb6c1171 244 Pfam PF00696 Amino acid kinase family 2 228 7.9E-22 T 28-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase CO689_RS01440 a3a8bb716e3c2fb9ba01d7f9eb6c1171 244 TIGRFAM TIGR00761 argB: acetylglutamate kinase 3 227 9.4E-51 T 28-03-2018 IPR004662 Acetylglutamate kinase GO:0003991|GO:0005737|GO:0006526 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 CO689_RS01440 a3a8bb716e3c2fb9ba01d7f9eb6c1171 244 SUPERFAMILY SSF53633 1 238 3.21E-40 T 28-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase CO689_RS01440 a3a8bb716e3c2fb9ba01d7f9eb6c1171 244 Gene3D G3DSA:3.40.1160.10 1 243 1.6E-30 T 28-03-2018 CO689_RS01440 a3a8bb716e3c2fb9ba01d7f9eb6c1171 244 PIRSF PIRSF000728 1 243 3.2E-54 T 28-03-2018 IPR004662 Acetylglutamate kinase GO:0003991|GO:0005737|GO:0006526 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 CO689_RS02880 f8ad0ca3091a1d660bdc18fbe83068ec 167 Pfam PF03780 Asp23 family, cell envelope-related function 38 143 5.3E-33 T 28-03-2018 IPR005531 Alkaline shock protein Asp23 CO689_RS05000 662103a15c8ce8c3afe9aec6e6f93eb7 495 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 255 262 - T 28-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 CO689_RS05000 662103a15c8ce8c3afe9aec6e6f93eb7 495 SUPERFAMILY SSF53720 9 488 1.83E-169 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CO689_RS05000 662103a15c8ce8c3afe9aec6e6f93eb7 495 Gene3D G3DSA:3.40.309.10 271 469 1.1E-73 T 28-03-2018 CO689_RS05000 662103a15c8ce8c3afe9aec6e6f93eb7 495 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 283 294 - T 28-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 CO689_RS05000 662103a15c8ce8c3afe9aec6e6f93eb7 495 Gene3D G3DSA:3.40.605.10 3 270 6.3E-96 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CO689_RS05000 662103a15c8ce8c3afe9aec6e6f93eb7 495 Pfam PF00171 Aldehyde dehydrogenase family 21 483 2.3E-176 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CO689_RS09825 6743f0eb183f7c05f27ab57e28b27615 140 Pfam PF04531 Bacteriophage holin 1 80 4.4E-25 T 28-03-2018 IPR006485 Bacteriophage holin CO689_RS09825 6743f0eb183f7c05f27ab57e28b27615 140 TIGRFAM TIGR01598 holin_phiLC3: holin, phage phi LC3 family 1 79 1.3E-28 T 28-03-2018 IPR006485 Bacteriophage holin CO689_RS02135 7b51ae642658753bafaf7f2911a2367e 362 Pfam PF04143 Sulphur transport 21 333 9.1E-94 T 28-03-2018 IPR007272 Sulphur transport domain CO689_RS06970 ca2d73956853c04dcfee490bf69fbe85 303 Pfam PF09991 Predicted membrane protein (DUF2232) 18 293 3.9E-52 T 28-03-2018 IPR018710 Protein of unknown function DUF2232 CO689_RS12885 b90193cb2728cd0b2aabf116c565ffaf 170 SUPERFAMILY SSF140663 3 118 1.96E-19 T 28-03-2018 IPR023203 TTHA0068-like domain CO689_RS12885 b90193cb2728cd0b2aabf116c565ffaf 170 Gene3D G3DSA:1.10.3450.10 2 133 1.1E-23 T 28-03-2018 IPR023203 TTHA0068-like domain CO689_RS12885 b90193cb2728cd0b2aabf116c565ffaf 170 Pfam PF03745 Domain of unknown function (DUF309) 5 64 4.0E-18 T 28-03-2018 IPR005500 Protein of unknown function DUF309 CO689_RS07420 844a5cc8ba1421cd5ea84d5531c9a818 199 Pfam PF03243 Alkylmercury lyase 61 193 1.4E-30 T 28-03-2018 IPR004927 Alkylmercury lyase GO:0018836|GO:0046413 CO689_RS07420 844a5cc8ba1421cd5ea84d5531c9a818 199 SUPERFAMILY SSF160387 66 194 3.14E-27 T 28-03-2018 CO689_RS05335 8f5eb6a425499593204830727012e3c3 301 Gene3D G3DSA:3.40.50.720 3 292 9.5E-44 T 28-03-2018 CO689_RS05335 8f5eb6a425499593204830727012e3c3 301 Pfam PF01370 NAD dependent epimerase/dehydratase family 5 215 5.0E-41 T 28-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 CO689_RS05335 8f5eb6a425499593204830727012e3c3 301 SUPERFAMILY SSF51735 5 291 1.7E-54 T 28-03-2018 IPR016040 NAD(P)-binding domain CO689_RS02980 e6d5e4ae86aa4cf5c5691e67fac7d9b6 280 Gene3D G3DSA:3.90.550.10 5 279 1.8E-48 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CO689_RS02980 e6d5e4ae86aa4cf5c5691e67fac7d9b6 280 Pfam PF01501 Glycosyl transferase family 8 7 255 8.5E-34 T 28-03-2018 IPR002495 Glycosyl transferase, family 8 GO:0016757 CO689_RS02980 e6d5e4ae86aa4cf5c5691e67fac7d9b6 280 SUPERFAMILY SSF53448 5 271 3.66E-56 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CO689_RS04740 2b3beddc86e0f6933c1cfd015dec4a97 404 SUPERFAMILY SSF46689 351 398 1.84E-12 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CO689_RS04740 2b3beddc86e0f6933c1cfd015dec4a97 404 SMART SM00342 314 397 1.8E-28 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CO689_RS04740 2b3beddc86e0f6933c1cfd015dec4a97 404 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 366 381 8.0E-6 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CO689_RS04740 2b3beddc86e0f6933c1cfd015dec4a97 404 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 381 397 8.0E-6 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CO689_RS04740 2b3beddc86e0f6933c1cfd015dec4a97 404 SUPERFAMILY SSF46689 297 348 2.33E-9 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CO689_RS04740 2b3beddc86e0f6933c1cfd015dec4a97 404 Pfam PF12833 Helix-turn-helix domain 320 398 3.0E-21 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CO689_RS04740 2b3beddc86e0f6933c1cfd015dec4a97 404 Gene3D G3DSA:3.90.1240.10 203 404 9.5E-32 T 28-03-2018 CO689_RS07450 4828f17039c78ce950905300987cd0cc 260 PIRSF PIRSF031503 1 260 3.8E-103 T 28-03-2018 IPR014564 Uncharacterised conserved protein UCP031503, transmembrane CO689_RS07450 4828f17039c78ce950905300987cd0cc 260 Pfam PF07907 YibE/F-like protein 5 244 2.9E-67 T 28-03-2018 IPR012507 YibE/F-like CO689_RS07790 cf9c6b7cf3b8648179aec4cfea50b567 261 Gene3D G3DSA:3.20.20.20 1 261 1.4E-94 T 28-03-2018 CO689_RS07790 cf9c6b7cf3b8648179aec4cfea50b567 261 SUPERFAMILY SSF51717 4 256 1.96E-85 T 28-03-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CO689_RS07790 cf9c6b7cf3b8648179aec4cfea50b567 261 ProSitePatterns PS00793 Dihydropteroate synthase signature 2. 40 53 - T 28-03-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CO689_RS07790 cf9c6b7cf3b8648179aec4cfea50b567 261 TIGRFAM TIGR01496 DHPS: dihydropteroate synthase 5 253 2.9E-92 T 28-03-2018 IPR006390 Dihydropteroate synthase GO:0004156|GO:0009396 KEGG: 00790+2.5.1.15|MetaCyc: PWY-6614 CO689_RS07790 cf9c6b7cf3b8648179aec4cfea50b567 261 Pfam PF00809 Pterin binding enzyme 7 241 2.6E-83 T 28-03-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CO689_RS07790 cf9c6b7cf3b8648179aec4cfea50b567 261 ProSitePatterns PS00792 Dihydropteroate synthase signature 1. 6 21 - T 28-03-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CO689_RS13410 3a350050a2332546632fd3cede5f08c0 307 Gene3D G3DSA:3.20.20.70 5 283 4.7E-4 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CO689_RS13410 3a350050a2332546632fd3cede5f08c0 307 Pfam PF01136 Peptidase family U32 73 304 3.8E-62 T 28-03-2018 IPR001539 Peptidase U32 GO:0006508|GO:0008233 CO689_RS01375 3b0eefea54e61d9b8985a6cd5610ed83 396 SUPERFAMILY SSF56300 1 291 3.14E-46 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CO689_RS01375 3b0eefea54e61d9b8985a6cd5610ed83 396 PIRSF PIRSF033091 1 396 3.2E-134 T 28-03-2018 IPR014576 Predicted phosphoesterase, YhaO type CO689_RS01375 3b0eefea54e61d9b8985a6cd5610ed83 396 Gene3D G3DSA:3.60.21.10 1 79 7.0E-15 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CO689_RS01375 3b0eefea54e61d9b8985a6cd5610ed83 396 Gene3D G3DSA:3.60.21.10 80 249 2.6E-19 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CO689_RS01375 3b0eefea54e61d9b8985a6cd5610ed83 396 Pfam PF00149 Calcineurin-like phosphoesterase 3 222 1.7E-13 T 28-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 CO689_RS13785 5c9e72a889766a1e1ad2b78658cfde6b 157 Hamap MF_00440 Transcriptional repressor NrdR [nrdR]. 1 154 79.138 T 28-03-2018 IPR003796 Ribonucleotide reductase regulator NrdR-like GO:0008270|GO:0045892 CO689_RS13785 5c9e72a889766a1e1ad2b78658cfde6b 157 Pfam PF03477 ATP cone domain 50 136 7.5E-18 T 28-03-2018 IPR005144 ATP-cone domain Reactome: R-HSA-499943 CO689_RS13785 5c9e72a889766a1e1ad2b78658cfde6b 157 Gene3D G3DSA:2.20.25.10 1 45 1.6E-4 T 28-03-2018 CO689_RS13785 5c9e72a889766a1e1ad2b78658cfde6b 157 TIGRFAM TIGR00244 TIGR00244: transcriptional regulator NrdR 1 145 1.4E-57 T 28-03-2018 IPR003796 Ribonucleotide reductase regulator NrdR-like GO:0008270|GO:0045892 CO689_RS08055 8b37b303da52741087a32befe876d4f2 84 SUPERFAMILY SSF55315 12 83 9.28E-16 T 28-03-2018 IPR029064 50S ribosomal protein L30e-like CO689_RS08055 8b37b303da52741087a32befe876d4f2 84 Pfam PF01248 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family 4 81 3.5E-10 T 28-03-2018 IPR004038 Ribosomal protein L7Ae/L30e/S12e/Gadd45 CO689_RS08055 8b37b303da52741087a32befe876d4f2 84 Gene3D G3DSA:3.30.1330.30 4 84 1.2E-11 T 28-03-2018 IPR029064 50S ribosomal protein L30e-like CO689_RS05395 0a3795d9b179842b4b6a8e971ef19c25 317 Gene3D G3DSA:2.60.120.10 27 238 6.1E-12 T 28-03-2018 IPR014710 RmlC-like jelly roll fold CO689_RS05395 0a3795d9b179842b4b6a8e971ef19c25 317 Pfam PF12833 Helix-turn-helix domain 210 292 2.1E-9 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CO689_RS05395 0a3795d9b179842b4b6a8e971ef19c25 317 SMART SM00342 204 290 5.2E-4 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CO689_RS05395 0a3795d9b179842b4b6a8e971ef19c25 317 Gene3D G3DSA:1.10.10.60 239 299 9.6E-7 T 28-03-2018 CO689_RS05395 0a3795d9b179842b4b6a8e971ef19c25 317 SUPERFAMILY SSF46689 187 239 1.7E-6 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CO689_RS11505 3a41286bb1e93c4b457fd9f2cc411ca3 289 Pfam PF03313 Serine dehydratase alpha chain 16 274 1.8E-75 T 28-03-2018 IPR005130 Serine dehydratase-like, alpha subunit CO689_RS11505 3a41286bb1e93c4b457fd9f2cc411ca3 289 TIGRFAM TIGR00718 sda_alpha: L-serine dehydratase, iron-sulfur-dependent, alpha subunit 1 288 7.4E-134 T 28-03-2018 IPR004642 Serine dehydratase, alpha subunit GO:0003941|GO:0006094 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17 CO689_RS11505 3a41286bb1e93c4b457fd9f2cc411ca3 289 Gene3D G3DSA:1.10.4100.10 58 270 2.4E-31 T 28-03-2018 CO689_RS08255 134fd2309a2e953230bea5d9f5aab282 497 Pfam PF13520 Amino acid permease 24 448 3.8E-43 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CO689_RS08255 134fd2309a2e953230bea5d9f5aab282 497 PIRSF PIRSF006060 4 474 5.3E-70 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CO689_RS12900 f607d7074de3a49a059fcb045b8711ca 180 PRINTS PR00502 NUDIX hydrolase family signature 71 85 1.1E-5 T 28-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CO689_RS12900 f607d7074de3a49a059fcb045b8711ca 180 PRINTS PR00502 NUDIX hydrolase family signature 85 100 1.1E-5 T 28-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CO689_RS12900 f607d7074de3a49a059fcb045b8711ca 180 Gene3D G3DSA:3.90.79.10 3 180 5.0E-43 T 28-03-2018 CO689_RS12900 f607d7074de3a49a059fcb045b8711ca 180 ProSitePatterns PS00893 Nudix box signature. 76 97 - T 28-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 CO689_RS12900 f607d7074de3a49a059fcb045b8711ca 180 SUPERFAMILY SSF55811 6 176 3.66E-49 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CO689_RS12900 f607d7074de3a49a059fcb045b8711ca 180 Pfam PF00293 NUDIX domain 43 160 1.4E-18 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 CO689_RS01025 72c4e0acfe3e465f444de6e4c8e1f551 276 Gene3D G3DSA:3.60.15.10 1 264 2.7E-41 T 28-03-2018 IPR001279 Metallo-beta-lactamase CO689_RS01025 72c4e0acfe3e465f444de6e4c8e1f551 276 SUPERFAMILY SSF56281 2 255 1.97E-38 T 28-03-2018 IPR001279 Metallo-beta-lactamase CO689_RS01025 72c4e0acfe3e465f444de6e4c8e1f551 276 SMART SM00849 47 252 3.2E-12 T 28-03-2018 IPR001279 Metallo-beta-lactamase CO689_RS01025 72c4e0acfe3e465f444de6e4c8e1f551 276 Pfam PF00753 Metallo-beta-lactamase superfamily 47 215 1.3E-19 T 28-03-2018 IPR001279 Metallo-beta-lactamase CO689_RS08190 cca27cd890d36a596ee76cc9d857e8df 122 Gene3D G3DSA:2.70.180.10 4 120 2.2E-47 T 28-03-2018 IPR014934 Protein of unknown function DUF1806 CO689_RS08190 cca27cd890d36a596ee76cc9d857e8df 122 SUPERFAMILY SSF89442 3 121 5.49E-49 T 28-03-2018 IPR014934 Protein of unknown function DUF1806 CO689_RS08190 cca27cd890d36a596ee76cc9d857e8df 122 Pfam PF08830 Protein of unknown function (DUF1806) 6 120 7.5E-49 T 28-03-2018 IPR014934 Protein of unknown function DUF1806 CO689_RS11210 e0c0b9b1ca8a4b52fd65762241846b12 132 Hamap MF_00910 Cell division protein FtsL [ftsL]. 43 125 13.181 T 28-03-2018 IPR011922 Cell division protein FtsL GO:0007049|GO:0016021|GO:0051301 CO689_RS11210 e0c0b9b1ca8a4b52fd65762241846b12 132 TIGRFAM TIGR02209 ftsL_broad: cell division protein FtsL 43 126 1.2E-21 T 28-03-2018 IPR011922 Cell division protein FtsL GO:0007049|GO:0016021|GO:0051301 CO689_RS11210 e0c0b9b1ca8a4b52fd65762241846b12 132 Pfam PF04977 Septum formation initiator 50 124 6.8E-11 T 28-03-2018 IPR007060 Septum formation initiator FtsL/DivIC GO:0007049 CO689_RS11290 66a0291c58e8098236a1c1bbf1dd94c0 161 SUPERFAMILY SSF54001 42 154 1.67E-16 T 28-03-2018 CO689_RS11290 66a0291c58e8098236a1c1bbf1dd94c0 161 Pfam PF05257 CHAP domain 45 124 1.1E-9 T 28-03-2018 IPR007921 CHAP domain CO689_RS05540 c55b98d2b86c6580bc25be93f124928b 519 Pfam PF02028 BCCT, betaine/carnitine/choline family transporter 5 487 3.5E-181 T 28-03-2018 IPR000060 BCCT transporter family GO:0005215|GO:0006810|GO:0016020 CO689_RS05540 c55b98d2b86c6580bc25be93f124928b 519 TIGRFAM TIGR00842 bcct: transporter, betaine/carnitine/choline transporter (BCCT) family 43 487 4.1E-155 T 28-03-2018 IPR000060 BCCT transporter family GO:0005215|GO:0006810|GO:0016020 CO689_RS06325 57dc8bccc8affe3364f98b170c36ec75 159 SUPERFAMILY SSF54637 3 156 9.23E-36 T 28-03-2018 IPR029069 HotDog domain CO689_RS06325 57dc8bccc8affe3364f98b170c36ec75 159 Gene3D G3DSA:3.10.129.10 1 136 4.2E-23 T 28-03-2018 CO689_RS06325 57dc8bccc8affe3364f98b170c36ec75 159 Pfam PF13279 Thioesterase-like superfamily 13 130 1.0E-21 T 28-03-2018 CO689_RS00385 51f77957170c79c15f1e3928c0fd05ba 312 Pfam PF13412 Winged helix-turn-helix DNA-binding 54 85 5.5E-6 T 28-03-2018 CO689_RS00385 51f77957170c79c15f1e3928c0fd05ba 312 SUPERFAMILY SSF46785 57 115 1.2E-5 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS00385 51f77957170c79c15f1e3928c0fd05ba 312 Gene3D G3DSA:1.10.10.10 14 131 1.9E-8 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS04765 4fba7f4769196df138a2264c78e2eed0 421 Gene3D G3DSA:1.10.10.660 40 103 3.7E-32 T 28-03-2018 IPR024033 Uncharacterised domain, YlbE CO689_RS04765 4fba7f4769196df138a2264c78e2eed0 421 Pfam PF06545 Protein of unknown function (DUF1116) 87 303 1.0E-98 T 28-03-2018 IPR009499 Protein of unknown function DUF1116 CO689_RS04765 4fba7f4769196df138a2264c78e2eed0 421 Gene3D G3DSA:3.90.1700.10 251 414 8.5E-77 T 28-03-2018 CO689_RS04765 4fba7f4769196df138a2264c78e2eed0 421 Gene3D G3DSA:3.90.1710.10 104 248 5.0E-60 T 28-03-2018 CO689_RS05770 a6fc5ea7ffc078525a25cd44e7114c27 277 Gene3D G3DSA:3.40.50.1110 1 244 3.3E-45 T 28-03-2018 CO689_RS05770 a6fc5ea7ffc078525a25cd44e7114c27 277 SUPERFAMILY SSF52266 2 265 1.67E-69 T 28-03-2018 IPR013830 SGNH hydrolase-type esterase domain CO689_RS05770 a6fc5ea7ffc078525a25cd44e7114c27 277 Pfam PF03629 Carbohydrate esterase, sialic acid-specific acetylesterase 4 223 2.9E-53 T 28-03-2018 IPR005181 Sialate O-acetylesterase domain CO689_RS07440 ace72f9f560870a60f0a932b5b50abd1 98 SUPERFAMILY SSF89360 1 91 3.66E-7 T 28-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 CO689_RS07440 ace72f9f560870a60f0a932b5b50abd1 98 Gene3D G3DSA:2.60.300.12 1 97 2.7E-8 T 28-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 CO689_RS11610 a63daa11a8ad4d8437c4eb64f2043a3d 54 Gene3D G3DSA:2.10.110.10 3 54 7.1E-4 T 28-03-2018 CO689_RS11165 4f50074b09343a4967b2605550edc6c4 220 Pfam PF07751 Abi-like protein 1 121 1.3E-11 T 28-03-2018 IPR011664 Abortive infection system protein AbiD/AbiF-like CO689_RS00410 776936537abb9b1a8878eef93faa379a 314 Gene3D G3DSA:3.40.190.100 141 257 1.6E-25 T 28-03-2018 CO689_RS00410 776936537abb9b1a8878eef93faa379a 314 SUPERFAMILY SSF53850 43 310 4.61E-53 T 28-03-2018 CO689_RS00410 776936537abb9b1a8878eef93faa379a 314 Pfam PF04069 Substrate binding domain of ABC-type glycine betaine transport system 45 298 7.4E-47 T 28-03-2018 IPR007210 ABC-type glycine betaine transport system, substrate-binding domain GO:0005215|GO:0006810 CO689_RS00410 776936537abb9b1a8878eef93faa379a 314 Gene3D G3DSA:3.40.190.10 44 140 7.7E-6 T 28-03-2018 CO689_RS03815 809486eaf7a422a96a70b91606936339 495 Gene3D G3DSA:3.50.50.60 1 441 2.6E-14 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CO689_RS03815 809486eaf7a422a96a70b91606936339 495 TIGRFAM TIGR01320 mal_quin_oxido: malate dehydrogenase (acceptor) 8 485 2.8E-216 T 28-03-2018 IPR006231 Malate:quinone-oxidoreductase GO:0006099|GO:0008924 KEGG: 00020+1.1.5.4|KEGG: 00620+1.1.5.4|MetaCyc: PWY-7254 CO689_RS03815 809486eaf7a422a96a70b91606936339 495 Hamap MF_00212 Probable malate:quinone oxidoreductase [mqo]. 4 491 52.738 T 28-03-2018 IPR006231 Malate:quinone-oxidoreductase GO:0006099|GO:0008924 KEGG: 00020+1.1.5.4|KEGG: 00620+1.1.5.4|MetaCyc: PWY-7254 CO689_RS03815 809486eaf7a422a96a70b91606936339 495 Pfam PF06039 Malate:quinone oxidoreductase (Mqo) 7 491 3.4E-233 T 28-03-2018 IPR006231 Malate:quinone-oxidoreductase GO:0006099|GO:0008924 KEGG: 00020+1.1.5.4|KEGG: 00620+1.1.5.4|MetaCyc: PWY-7254 CO689_RS03815 809486eaf7a422a96a70b91606936339 495 SUPERFAMILY SSF51905 7 274 1.81E-21 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CO689_RS12640 dbcd00c495b4241715d5670ba3a48b69 235 Pfam PF02592 Putative vitamin uptake transporter 58 219 5.7E-44 T 28-03-2018 IPR003744 Queuosine precursor transporter CO689_RS12640 dbcd00c495b4241715d5670ba3a48b69 235 TIGRFAM TIGR00697 TIGR00697: conserved hypothetical integral membrane protein 27 225 4.8E-58 T 28-03-2018 IPR003744 Queuosine precursor transporter CO689_RS06915 54b61382e2600f96977119ec3d1802b7 262 Pfam PF09648 YycH protein 40 253 2.4E-42 T 28-03-2018 IPR018604 Regulatory protein YycH-like GO:0016021 CO689_RS09055 3dc032c8b253df945cc2bef38a8bf394 165 Pfam PF12821 Threonine/Serine exporter, ThrE 9 134 3.7E-37 T 28-03-2018 IPR024528 Threonine/Serine exporter, ThrE CO689_RS09560 bc5e6bdeb858ebcee0a2c8ad24746d45 257 Pfam PF09669 Phage regulatory protein Rha (Phage_pRha) 15 104 8.5E-24 T 28-03-2018 IPR014054 Bacteriophage regulatory protein, Rha family CO689_RS10550 30b19e5275cebf69b7e2d9fc89b984d7 336 Pfam PF01757 Acyltransferase family 10 305 1.4E-18 T 28-03-2018 IPR002656 Acyltransferase 3 GO:0016747 CO689_RS10860 a4851b2cb8942a634db7bfca303e1645 370 SUPERFAMILY SSF52518 23 366 1.22E-101 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CO689_RS10860 a4851b2cb8942a634db7bfca303e1645 370 Gene3D G3DSA:3.40.50.970 2 363 2.2E-87 T 28-03-2018 CO689_RS10860 a4851b2cb8942a634db7bfca303e1645 370 TIGRFAM TIGR03181 PDH_E1_alph_x: pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit 23 363 8.9E-147 T 28-03-2018 IPR017596 Pyruvate dehydrogenase E1 component subunit alpha/BCKADH E1-alpha KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 CO689_RS10860 a4851b2cb8942a634db7bfca303e1645 370 Pfam PF00676 Dehydrogenase E1 component 53 341 1.8E-100 T 28-03-2018 IPR001017 Dehydrogenase, E1 component GO:0008152|GO:0016624 Reactome: R-HSA-389661 CO689_RS09145 0eeff62563eb04e5d7d9ec8131ade288 275 TIGRFAM TIGR00544 lgt: prolipoprotein diacylglyceryl transferase 8 260 2.2E-75 T 28-03-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 CO689_RS09145 0eeff62563eb04e5d7d9ec8131ade288 275 Hamap MF_01147 Prolipoprotein diacylglyceryl transferase [lgt]. 7 260 17.551 T 28-03-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 CO689_RS09145 0eeff62563eb04e5d7d9ec8131ade288 275 ProSitePatterns PS01311 Prolipoprotein diacylglyceryl transferase signature. 136 148 - T 28-03-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 CO689_RS09145 0eeff62563eb04e5d7d9ec8131ade288 275 Pfam PF01790 Prolipoprotein diacylglyceryl transferase 10 255 4.6E-76 T 28-03-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 CO689_RS02325 3cb7f068ff66d940f3f80c38c7847425 402 Pfam PF01098 Cell cycle protein 18 386 2.9E-93 T 28-03-2018 IPR001182 Probable peptidoglycan glycosyltransferase FtsW/RodA GO:0016021|GO:0051301 CO689_RS12895 0941223d0eb70ac4df4bb883b6031abc 150 Pfam PF01475 Ferric uptake regulator family 15 136 3.3E-39 T 28-03-2018 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 CO689_RS12895 0941223d0eb70ac4df4bb883b6031abc 150 Gene3D G3DSA:1.10.10.10 1 87 1.7E-25 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS12895 0941223d0eb70ac4df4bb883b6031abc 150 SUPERFAMILY SSF46785 7 141 2.93E-39 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS12500 43ff281689640e6d647cab8aa107b6e5 89 Pfam PF00708 Acylphosphatase 5 87 6.7E-23 T 28-03-2018 IPR001792 Acylphosphatase-like domain KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 CO689_RS12500 43ff281689640e6d647cab8aa107b6e5 89 SUPERFAMILY SSF54975 1 87 1.16E-23 T 28-03-2018 IPR001792 Acylphosphatase-like domain KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 CO689_RS12500 43ff281689640e6d647cab8aa107b6e5 89 Gene3D G3DSA:3.30.70.100 1 89 5.9E-26 T 28-03-2018 CO689_RS12500 43ff281689640e6d647cab8aa107b6e5 89 ProSitePatterns PS00150 Acylphosphatase signature 1. 8 18 - T 28-03-2018 IPR017968 Acylphosphatase, conserved site KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 CO689_RS10295 13a2d7c6d9eba34dd67e646adac73ebc 361 Pfam PF01594 AI-2E family transporter 16 344 1.6E-68 T 28-03-2018 IPR002549 Transmembrane protein TqsA-like CO689_RS00370 8343d35e2e8c4290565da020e8fc054a 387 SUPERFAMILY SSF103473 4 379 3.66E-39 T 28-03-2018 IPR020846 Major facilitator superfamily domain CO689_RS00370 8343d35e2e8c4290565da020e8fc054a 387 Pfam PF07690 Major Facilitator Superfamily 24 343 2.9E-17 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CO689_RS00370 8343d35e2e8c4290565da020e8fc054a 387 Gene3D G3DSA:1.20.1250.20 5 194 2.9E-15 T 28-03-2018 CO689_RS00370 8343d35e2e8c4290565da020e8fc054a 387 Gene3D G3DSA:1.20.1250.20 198 379 2.3E-17 T 28-03-2018 CO689_RS12195 769b508cef45609933fdc747b2b81ef4 155 Pfam PF07301 Protein of unknown function (DUF1453) 6 149 2.4E-57 T 28-03-2018 IPR009916 Protein of unknown function DUF1453 CO689_RS12195 769b508cef45609933fdc747b2b81ef4 155 PIRSF PIRSF021441 1 155 5.5E-67 T 28-03-2018 IPR031306 CcdC protein CO689_RS04910 359cba0f3f256d1b972ab2b71c626940 474 Pfam PF13520 Amino acid permease 12 414 1.9E-69 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CO689_RS04910 359cba0f3f256d1b972ab2b71c626940 474 PIRSF PIRSF006060 1 472 2.9E-51 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CO689_RS04910 359cba0f3f256d1b972ab2b71c626940 474 TIGRFAM TIGR03810 arg_ornith_anti: arginine-ornithine antiporter 7 473 6.5E-185 T 28-03-2018 IPR022461 Arginine/ornithine antiporter GO:0005887|GO:0006527|GO:0043858 CO689_RS04910 359cba0f3f256d1b972ab2b71c626940 474 TIGRFAM TIGR00905 2A0302: transporter, basic amino acid/polyamine antiporter (APA) family 2 472 7.7E-170 T 28-03-2018 IPR004754 Amino acid antiporter GO:0006865|GO:0016021 CO689_RS04550 8a79e08f1a6187088bea73c8f1ac357e 123 Pfam PF04343 Protein of unknown function, DUF488 4 117 9.8E-32 T 28-03-2018 IPR007438 Protein of unknown function DUF488 CO689_RS02355 08023a1949dac3e96b138100789f5677 97 Pfam PF02583 Metal-sensitive transcriptional repressor 14 92 9.0E-27 T 28-03-2018 IPR003735 Metal-sensitive transcriptional repressor GO:0003677|GO:0006355|GO:0046872 CO689_RS06855 9f9179f2e6ff6fc5d0189bf801266021 458 PIRSF PIRSF006060 1 458 2.8E-69 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CO689_RS06855 9f9179f2e6ff6fc5d0189bf801266021 458 Pfam PF00324 Amino acid permease 14 449 1.7E-105 T 28-03-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0006810|GO:0016020|GO:0055085 CO689_RS12400 8b03055978373662c3afe57deb7df1c6 115 Gene3D G3DSA:1.20.1640.10 5 109 8.3E-4 T 28-03-2018 CO689_RS09855 cd1af50b0432b381e356d08503b460be 282 Pfam PF01904 Protein of unknown function DUF72 19 265 7.9E-59 T 28-03-2018 IPR002763 Protein of unknown function DUF72 CO689_RS09855 cd1af50b0432b381e356d08503b460be 282 SUPERFAMILY SSF117396 1 269 1.28E-80 T 28-03-2018 IPR002763 Protein of unknown function DUF72 CO689_RS09855 cd1af50b0432b381e356d08503b460be 282 Gene3D G3DSA:3.20.20.410 1 282 4.9E-79 T 28-03-2018 IPR002763 Protein of unknown function DUF72 CO689_RS10825 3e27850e561ca7486077478cabe7c605 345 Pfam PF02322 Cytochrome bd terminal oxidase subunit II 6 329 3.8E-34 T 28-03-2018 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 CO689_RS10270 a1a80564361c9254330f210f68a9abd1 292 SUPERFAMILY SSF55120 68 276 5.55E-56 T 28-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 CO689_RS10270 a1a80564361c9254330f210f68a9abd1 292 Gene3D G3DSA:3.30.2350.10 74 291 9.0E-50 T 28-03-2018 CO689_RS10270 a1a80564361c9254330f210f68a9abd1 292 Gene3D G3DSA:3.10.290.10 11 66 6.2E-4 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CO689_RS10270 a1a80564361c9254330f210f68a9abd1 292 Pfam PF00849 RNA pseudouridylate synthase 83 230 2.6E-24 T 28-03-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 CO689_RS00320 1ff0c974a64704edbdfe097eed838ab7 224 SUPERFAMILY SSF53098 69 215 3.29E-10 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CO689_RS00320 1ff0c974a64704edbdfe097eed838ab7 224 Gene3D G3DSA:1.10.10.10 5 67 9.7E-5 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS00320 1ff0c974a64704edbdfe097eed838ab7 224 Pfam PF13610 DDE domain 72 202 2.6E-39 T 28-03-2018 IPR032874 DDE domain CO689_RS00320 1ff0c974a64704edbdfe097eed838ab7 224 Gene3D G3DSA:3.30.420.10 68 219 1.7E-16 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CO689_RS08040 6c12c173e92261d64bb9b3124b5d81fd 201 Gene3D G3DSA:3.40.50.150 9 201 7.9E-32 T 28-03-2018 CO689_RS08040 6c12c173e92261d64bb9b3124b5d81fd 201 Pfam PF05175 Methyltransferase small domain 27 198 4.7E-52 T 28-03-2018 IPR007848 Methyltransferase small domain GO:0008168 CO689_RS08040 6c12c173e92261d64bb9b3124b5d81fd 201 SUPERFAMILY SSF53335 7 200 1.34E-38 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CO689_RS09230 54630fc47ae9c478f316cec6114a3bb6 99 Pfam PF07342 Protein of unknown function (DUF1474) 1 98 2.9E-22 T 28-03-2018 IPR009942 Protein of unknown function DUF1474 CO689_RS07330 eaedff279d9c4fe5b6ffbe77d6aee57b 210 Gene3D G3DSA:3.40.190.10 1 129 2.1E-4 T 28-03-2018 CO689_RS07330 eaedff279d9c4fe5b6ffbe77d6aee57b 210 Pfam PF16729 Domain of unknown function (DUF5067) 33 166 9.1E-20 T 28-03-2018 IPR031989 Domain of unknown function DUF5067 CO689_RS13715 63e50063d4957dbca540564bd0dac1f1 274 Pfam PF01578 Cytochrome C assembly protein 69 266 5.5E-18 T 28-03-2018 IPR002541 Cytochrome c assembly protein GO:0017004|GO:0020037 CO689_RS10015 2ea6c4a0b098c74f3ea8da0b972f1ad1 127 SUPERFAMILY SSF141251 2 119 1.96E-44 T 28-03-2018 CO689_RS10015 2ea6c4a0b098c74f3ea8da0b972f1ad1 127 SMART SM01298 7 120 1.5E-67 T 28-03-2018 IPR014916 Kinase associated protein B CO689_RS10015 2ea6c4a0b098c74f3ea8da0b972f1ad1 127 Pfam PF08810 Kinase associated protein B 7 118 6.0E-41 T 28-03-2018 IPR014916 Kinase associated protein B CO689_RS05785 3559f8de7d8e95b791baf520081cabb0 194 Gene3D G3DSA:3.30.1240.10 130 194 0.0018 T 28-03-2018 CO689_RS05785 3559f8de7d8e95b791baf520081cabb0 194 Pfam PF05378 Hydantoinase/oxoprolinase N-terminal region 38 174 5.9E-24 T 28-03-2018 IPR008040 Hydantoinaseoxoprolinase, N-terminal Reactome: R-HSA-174403 CO689_RS06610 06f2494573b1dffe640ef66ade99c0d5 207 Pfam PF01810 LysE type translocator 14 202 2.2E-34 T 28-03-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 CO689_RS06610 06f2494573b1dffe640ef66ade99c0d5 207 PIRSF PIRSF006324 1 207 2.0E-49 T 28-03-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 CO689_RS03140 7e5533333897386e401369aceac3f6f2 91 SUPERFAMILY SSF54189 1 86 6.83E-30 T 28-03-2018 IPR012678 Ribosomal protein L23/L15e core domain GO:0003735|GO:0005622|GO:0005840|GO:0006412 CO689_RS03140 7e5533333897386e401369aceac3f6f2 91 Pfam PF00276 Ribosomal protein L23 5 86 3.8E-31 T 28-03-2018 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 CO689_RS03140 7e5533333897386e401369aceac3f6f2 91 Hamap MF_01369_B 50S ribosomal protein L23 [rplW]. 4 91 20.157 T 28-03-2018 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 CO689_RS03140 7e5533333897386e401369aceac3f6f2 91 Gene3D G3DSA:3.30.70.330 1 91 1.5E-30 T 28-03-2018 CO689_RS10145 d136d70588b448a29b8c39b0748264da 67 Pfam PF11151 Protein of unknown function (DUF2929) 1 55 1.4E-18 T 28-03-2018 IPR021324 Protein of unknown function DUF2929 CO689_RS07580 71fcc39050f2ad8a380a05faac0ee21c 268 Pfam PF04468 PSP1 C-terminal conserved region 62 147 3.8E-27 T 28-03-2018 IPR007557 PSP1, C-terminal CO689_RS02295 911ffb8cac6e64d4ad2fa8593a46fdaa 165 Pfam PF03703 Bacterial PH domain 76 146 1.6E-13 T 28-03-2018 IPR005182 Domain of unknown function DUF304 CO689_RS06085 3863b35d949ac343fce136da2c624e10 276 Pfam PF03613 PTS system mannose/fructose/sorbose family IID component 13 272 3.4E-87 T 28-03-2018 IPR004704 Phosphotransferase system, mannose/fructose/sorbose family IID component GO:0009401|GO:0016021 CO689_RS05750 1eb14a1ba3234caa8fb48646b82eddae 237 Pfam PF05908 Poly-gamma-glutamate hydrolase 36 228 3.1E-57 T 28-03-2018 IPR008585 Poly-gamma-glutamate hydrolase CO689_RS08520 73cb56338ea0378466dbf980e5dea6bf 278 Pfam PF10035 Uncharacterized protein conserved in bacteria (DUF2179) 217 271 2.3E-23 T 28-03-2018 IPR019264 Domain of unknown function DUF2179 CO689_RS08520 73cb56338ea0378466dbf980e5dea6bf 278 PIRSF PIRSF006483 1 278 1.6E-75 T 28-03-2018 IPR003740 Uncharacterised membrane protein YitT CO689_RS08520 73cb56338ea0378466dbf980e5dea6bf 278 Pfam PF02588 Uncharacterised 5xTM membrane BCR, YitT family COG1284 9 211 1.7E-55 T 28-03-2018 IPR003740 Uncharacterised membrane protein YitT CO689_RS08200 fe5527ec077e7080665c8f153df3c120 292 Pfam PF02649 Type I GTP cyclohydrolase folE2 33 286 1.9E-69 T 28-03-2018 IPR003801 GTP cyclohydrolase FolE2/MptA GO:0003933 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852 CO689_RS08200 fe5527ec077e7080665c8f153df3c120 292 Gene3D G3DSA:3.10.270.10 32 289 3.2E-81 T 28-03-2018 CO689_RS08200 fe5527ec077e7080665c8f153df3c120 292 Hamap MF_01527_B GTP cyclohydrolase FolE2 [folE2]. 33 291 31.23 T 28-03-2018 IPR022838 GTP cyclohydrolase FolE2 GO:0003934|GO:0035998 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852 CO689_RS08200 fe5527ec077e7080665c8f153df3c120 292 TIGRFAM TIGR00294 TIGR00294: GTP cyclohydrolase 14 287 4.7E-51 T 28-03-2018 IPR003801 GTP cyclohydrolase FolE2/MptA GO:0003933 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852 CO689_RS09020 3e3222406b054c83e3f4cf584e59013c 108 SUPERFAMILY SSF161219 9 94 1.44E-18 T 28-03-2018 CO689_RS09020 3e3222406b054c83e3f4cf584e59013c 108 Pfam PF05495 CHY zinc finger 19 91 7.6E-12 T 28-03-2018 IPR008913 Zinc finger, CHY-type GO:0008270 Reactome: R-HSA-110320|Reactome: R-HSA-983168 CO689_RS09020 3e3222406b054c83e3f4cf584e59013c 108 PIRSF PIRSF017292 3 108 2.2E-39 T 28-03-2018 IPR016694 Protein of unknown function UCP017292, zinc finger, CHY-type CO689_RS03790 d6fb5e8d2faca194c5c419cc4199f9a8 329 Pfam PF02698 DUF218 domain 150 268 1.1E-30 T 28-03-2018 IPR003848 Domain of unknown function DUF218 CO689_RS03790 d6fb5e8d2faca194c5c419cc4199f9a8 329 Gene3D G3DSA:3.40.50.620 144 282 8.8E-35 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CO689_RS04805 de661b30ac57c8fa42441ff4d53cee25 497 Pfam PF02133 Permease for cytosine/purines, uracil, thiamine, allantoin 28 468 6.9E-89 T 28-03-2018 IPR001248 Purine-cytosine permease GO:0005215|GO:0016020|GO:0055085 CO689_RS04195 860fbe24f7b208e4aaf4e84a89d9491e 262 Pfam PF02517 CAAX protease self-immunity 157 246 1.5E-12 T 28-03-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 CO689_RS01740 50c06a3319a4be66a871142ed8f72c5b 131 Gene3D G3DSA:1.20.5.50 13 126 0.0014 T 28-03-2018 CO689_RS06015 388cb8c0460af829a34480dc4b54551b 498 Pfam PF01970 Tripartite tricarboxylate transporter TctA family 20 438 4.5E-145 T 28-03-2018 IPR002823 Protein of unknown function DUF112, transmembrane CO689_RS01995 64a143948ded1677be30676ff4784fef 547 Pfam PF03354 Phage Terminase 75 532 6.0E-75 T 28-03-2018 IPR005021 Terminase large subunit, Lambdalikevirus-type CO689_RS01995 64a143948ded1677be30676ff4784fef 547 Gene3D G3DSA:3.40.50.300 70 248 7.0E-4 T 28-03-2018 CO689_RS11700 f90bc9d8e806da2ca7f4ec329c355067 260 Pfam PF01148 Cytidylyltransferase family 3 257 1.3E-71 T 28-03-2018 CO689_RS11700 f90bc9d8e806da2ca7f4ec329c355067 260 ProSitePatterns PS01315 Phosphatidate cytidylyltransferase signature. 218 244 - T 28-03-2018 IPR000374 Phosphatidate cytidylyltransferase GO:0016020|GO:0016772 KEGG: 00564+2.7.7.41|KEGG: 04070+2.7.7.41|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7817 CO689_RS06875 7bcf43faf9e3b41e8aeb63ee7035e25b 103 Pfam PF06124 Staphylococcal protein of unknown function (DUF960) 3 102 4.2E-16 T 28-03-2018 IPR009303 Protein of unknown function DUF960 CO689_RS06875 7bcf43faf9e3b41e8aeb63ee7035e25b 103 Gene3D G3DSA:3.10.450.150 1 102 1.9E-27 T 28-03-2018 CO689_RS09655 187263276e01b8652944673bab2ae2e9 173 Pfam PF07768 PVL ORF-50-like family 79 157 1.1E-4 T 28-03-2018 IPR011688 PVL Orf50 family CO689_RS04255 597e0b98e85498556277044f3991de8a 134 Pfam PF09954 Uncharacterized protein conserved in bacteria (DUF2188) 87 133 1.2E-8 T 28-03-2018 IPR018691 Protein of unknown function DUF2188 CO689_RS04665 9a252ea6861237abc8199ccb4d7d2229 356 Pfam PF13303 Phosphotransferase system, EIIC 20 352 3.5E-86 T 28-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 CO689_RS06760 ab5ae7ced61fc2acb21cea2264f5d92c 227 Gene3D G3DSA:3.40.50.880 1 227 2.7E-49 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CO689_RS06760 ab5ae7ced61fc2acb21cea2264f5d92c 227 Pfam PF01965 DJ-1/PfpI family 27 221 2.6E-11 T 28-03-2018 IPR002818 DJ-1/PfpI CO689_RS06760 ab5ae7ced61fc2acb21cea2264f5d92c 227 SUPERFAMILY SSF52317 1 224 3.52E-70 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CO689_RS12695 a76057f0424dd9d2f9c53c4195a76dbb 759 Pfam PF00905 Penicillin binding protein transpeptidase domain 358 617 2.4E-25 T 28-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 CO689_RS12695 a76057f0424dd9d2f9c53c4195a76dbb 759 Gene3D G3DSA:1.10.3810.10 69 269 1.1E-72 T 28-03-2018 IPR001264 Glycosyl transferase, family 51 CO689_RS12695 a76057f0424dd9d2f9c53c4195a76dbb 759 Pfam PF00912 Transglycosylase 77 252 8.1E-61 T 28-03-2018 IPR001264 Glycosyl transferase, family 51 CO689_RS12695 a76057f0424dd9d2f9c53c4195a76dbb 759 Gene3D G3DSA:3.40.710.10 282 739 1.5E-65 T 28-03-2018 CO689_RS12695 a76057f0424dd9d2f9c53c4195a76dbb 759 SUPERFAMILY SSF53955 67 276 2.81E-68 T 28-03-2018 IPR023346 Lysozyme-like domain CO689_RS12695 a76057f0424dd9d2f9c53c4195a76dbb 759 SUPERFAMILY SSF56601 294 664 2.82E-79 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CO689_RS00190 b76b5aed5bf6626fa352373f1fa73040 234 Pfam PF16715 Cyclodipeptide synthase 4 224 3.3E-73 T 28-03-2018 IPR030903 Cyclodileucine synthase GO:0016755 CO689_RS00190 b76b5aed5bf6626fa352373f1fa73040 234 TIGRFAM TIGR04539 tRNA_cyclodipep: tRNA-dependent cyclodipeptide synthase 4 224 3.2E-68 T 28-03-2018 IPR030903 Cyclodileucine synthase GO:0016755 CO689_RS12390 91b77bbf4b7991f8a9d03f31fccc99b8 328 Gene3D G3DSA:1.10.3720.10 3 297 2.9E-39 T 28-03-2018 CO689_RS12390 91b77bbf4b7991f8a9d03f31fccc99b8 328 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 118 308 1.8E-34 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CO689_RS12390 91b77bbf4b7991f8a9d03f31fccc99b8 328 SUPERFAMILY SSF161098 95 291 9.55E-22 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CO689_RS09730 28d2e9e9db7770e6b48a3a0db2ed71d5 567 Pfam PF03354 Phage Terminase 72 551 7.6E-191 T 28-03-2018 IPR005021 Terminase large subunit, Lambdalikevirus-type CO689_RS03625 3a93a0dd55c3a6cc0a865db940992d91 387 Pfam PF00916 Sulfate permease family 138 332 4.7E-26 T 28-03-2018 IPR011547 SLC26A/SulP transporter domain GO:0008272|GO:0015116|GO:0016021 CO689_RS00595 03cb0d9fde210282bca76833889f955a 137 Gene3D G3DSA:3.40.50.620 2 137 1.1E-25 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CO689_RS00595 03cb0d9fde210282bca76833889f955a 137 PRINTS PR01438 Universal stress protein signature 2 20 7.3E-17 T 28-03-2018 IPR006015 Universal stress protein A CO689_RS00595 03cb0d9fde210282bca76833889f955a 137 PRINTS PR01438 Universal stress protein signature 97 109 7.3E-17 T 28-03-2018 IPR006015 Universal stress protein A CO689_RS00595 03cb0d9fde210282bca76833889f955a 137 PRINTS PR01438 Universal stress protein signature 115 137 7.3E-17 T 28-03-2018 IPR006015 Universal stress protein A CO689_RS00595 03cb0d9fde210282bca76833889f955a 137 Pfam PF00582 Universal stress protein family 1 137 4.4E-23 T 28-03-2018 IPR006016 UspA GO:0006950 CO689_RS00595 03cb0d9fde210282bca76833889f955a 137 SUPERFAMILY SSF52402 2 137 1.33E-24 T 28-03-2018 CO689_RS02795 d74b09c706e12e5b9b79dedc50eb0793 152 Pfam PF17080 Multidrug Resistance efflux pump 9 150 4.6E-61 T 28-03-2018 IPR031396 Multidrug resistance efflux pump SepA CO689_RS04935 0808f451bf17b02766d935a072f54d51 294 Gene3D G3DSA:1.10.10.10 1 59 3.0E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS04935 0808f451bf17b02766d935a072f54d51 294 Pfam PF08279 HTH domain 6 48 2.6E-5 T 28-03-2018 IPR013196 Helix-turn-helix, type 11 CO689_RS06885 7dce9df81384f61a6bdae3198a8406f3 67 Pfam PF11867 Domain of unknown function (DUF3387) 1 64 1.5E-21 T 28-03-2018 IPR021810 Protein of unknown function DUF3387 CO689_RS03000 191ed2f4343f9db44186c0539434c6ec 268 Hamap MF_01461 Energy-coupling factor transporter transmembrane protein EcfT [ecfT]. 2 265 33.374 T 28-03-2018 IPR024919 ECF transporter transmembrane protein EcfT GO:0005215|GO:0006810|GO:0016021 CO689_RS03000 191ed2f4343f9db44186c0539434c6ec 268 Pfam PF02361 Cobalt transport protein 15 234 1.9E-44 T 28-03-2018 IPR003339 ABC/ECF transporter, transmembrane component CO689_RS06430 0e5bc1884c6eded672957438c17da329 222 Pfam PF04131 Putative N-acetylmannosamine-6-phosphate epimerase 24 222 3.4E-67 T 28-03-2018 IPR007260 Putative N-acetylmannosamine-6-phosphate epimerase GO:0006051|GO:0047465 KEGG: 00520+5.1.3.9 CO689_RS06430 0e5bc1884c6eded672957438c17da329 222 Hamap MF_01235 Putative N-acetylmannosamine-6-phosphate 2-epimerase [nanE]. 1 221 40.047 T 28-03-2018 IPR007260 Putative N-acetylmannosamine-6-phosphate epimerase GO:0006051|GO:0047465 KEGG: 00520+5.1.3.9 CO689_RS06430 0e5bc1884c6eded672957438c17da329 222 Gene3D G3DSA:3.20.20.70 2 222 1.6E-35 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CO689_RS06430 0e5bc1884c6eded672957438c17da329 222 SUPERFAMILY SSF51366 2 220 1.79E-62 T 28-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 CO689_RS05365 f1d79382a14ce0cceb383d1727bef13c 184 SUPERFAMILY SSF46785 10 138 5.79E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS05365 f1d79382a14ce0cceb383d1727bef13c 184 PIRSF PIRSF006707 1 181 2.1E-43 T 28-03-2018 IPR026282 DNA-binding protein, MJ1563 type CO689_RS05365 f1d79382a14ce0cceb383d1727bef13c 184 Gene3D G3DSA:1.10.10.10 3 168 2.4E-7 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS06010 9e03accc3f66247235d6512fae43a781 147 Pfam PF07331 Tripartite tricarboxylate transporter TctB family 12 147 1.8E-22 T 28-03-2018 IPR009936 Protein of unknown function DUF1468 CO689_RS12595 c04f78a99cf9b7df0f800c96335515b1 166 SUPERFAMILY SSF51261 10 154 7.67E-55 T 28-03-2018 IPR011055 Duplicated hybrid motif CO689_RS12595 c04f78a99cf9b7df0f800c96335515b1 166 Gene3D G3DSA:2.70.70.10 4 165 8.3E-61 T 28-03-2018 CO689_RS12595 c04f78a99cf9b7df0f800c96335515b1 166 Pfam PF00358 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 17 141 1.0E-52 T 28-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 CO689_RS12595 c04f78a99cf9b7df0f800c96335515b1 166 ProSitePatterns PS00371 PTS EIIA domains phosphorylation site signature 1. 80 92 - T 28-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 CO689_RS12595 c04f78a99cf9b7df0f800c96335515b1 166 TIGRFAM TIGR00830 PTBA: PTS system, glucose subfamily, IIA component 18 138 8.1E-46 T 28-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 CO689_RS01385 3b9dc1963f3fa1e3c4a440db63326a11 376 Pfam PF04286 Protein of unknown function (DUF445) 12 375 2.1E-69 T 28-03-2018 IPR007383 Protein of unknown function DUF445 CO689_RS01385 3b9dc1963f3fa1e3c4a440db63326a11 376 PIRSF PIRSF032178 1 376 5.8E-115 T 28-03-2018 IPR016991 Protein of unknown function UCP032178 CO689_RS08575 5d47a3a09f262a86bbd0f083fd63815b 632 Pfam PF02687 FtsX-like permease family 85 178 1.1E-6 T 28-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 CO689_RS08575 5d47a3a09f262a86bbd0f083fd63815b 632 PIRSF PIRSF018968 1 632 2.0E-98 T 28-03-2018 IPR027022 ABC transporter permease protein, BceB-type GO:0006810 CO689_RS10935 94437ba96e29d443218d287b5c69b9bf 63 Pfam PF17259 Family of unknown function (DUF5325) 4 62 1.2E-17 T 28-03-2018 IPR035211 Protein of unknown function DUF5325 CO689_RS01765 b8bb2184fd064d12184194fd5579f487 185 TIGRFAM TIGR00573 dnaq: exonuclease, DNA polymerase III, epsilon subunit family 4 167 6.8E-21 T 28-03-2018 IPR006054 DNA polymerase III epsilon subunit, exonuclease domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CO689_RS01765 b8bb2184fd064d12184194fd5579f487 185 Pfam PF00929 Exonuclease 8 159 5.5E-25 T 28-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III CO689_RS01765 b8bb2184fd064d12184194fd5579f487 185 SMART SM00479 6 169 7.6E-25 T 28-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III CO689_RS01765 b8bb2184fd064d12184194fd5579f487 185 SUPERFAMILY SSF53098 5 170 7.59E-43 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CO689_RS01765 b8bb2184fd064d12184194fd5579f487 185 Gene3D G3DSA:3.30.420.10 3 180 1.8E-36 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CO689_RS04995 a06aefe4973f8e0616558c9737f97247 381 SUPERFAMILY SSF53448 3 257 2.06E-33 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CO689_RS04995 a06aefe4973f8e0616558c9737f97247 381 Pfam PF00535 Glycosyl transferase family 2 7 171 1.0E-27 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CO689_RS04995 a06aefe4973f8e0616558c9737f97247 381 Gene3D G3DSA:3.90.550.10 3 339 1.1E-26 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CO689_RS12635 6975faea5890586c4cf9caf280df5482 64 Pfam PF10782 Zinc-finger 8 64 1.1E-25 T 28-03-2018 IPR019718 Protein of unknown function DUF2602 CO689_RS03515 996a7e870c89a2be5f29b2ede73e7ca5 156 Pfam PF07849 Protein of unknown function (DUF1641) 116 154 2.6E-9 T 28-03-2018 IPR012440 Protein of unknown function DUF1641 CO689_RS07615 362b57a5188217105c9adcd53953298b 94 Pfam PF07901 Protein of unknown function (DUF1672) 1 85 2.7E-30 T 28-03-2018 IPR012873 Protein of unknown function DUF1672 CO689_RS03820 a023755f465b6507b47c141c63b32037 385 SUPERFAMILY SSF53756 7 382 1.61E-47 T 28-03-2018 CO689_RS03820 a023755f465b6507b47c141c63b32037 385 Gene3D G3DSA:3.40.50.2000 214 376 1.8E-29 T 28-03-2018 CO689_RS03820 a023755f465b6507b47c141c63b32037 385 Pfam PF00534 Glycosyl transferases group 1 204 361 1.9E-27 T 28-03-2018 IPR001296 Glycosyl transferase, family 1 CO689_RS03820 a023755f465b6507b47c141c63b32037 385 Gene3D G3DSA:3.40.50.2000 3 213 3.0E-4 T 28-03-2018 CO689_RS04785 f404e7cbf1c68b11508dc42df682fc4f 262 SUPERFAMILY SSF51182 14 261 7.26E-68 T 28-03-2018 IPR011051 RmlC-like cupin domain CO689_RS04785 f404e7cbf1c68b11508dc42df682fc4f 262 Gene3D G3DSA:2.60.120.10 1 262 5.1E-43 T 28-03-2018 IPR014710 RmlC-like jelly roll fold CO689_RS04785 f404e7cbf1c68b11508dc42df682fc4f 262 Pfam PF07883 Cupin domain 185 245 1.3E-7 T 28-03-2018 IPR013096 Cupin 2, conserved barrel CO689_RS04785 f404e7cbf1c68b11508dc42df682fc4f 262 TIGRFAM TIGR03214 ura-cupin: putative allantoin catabolism protein 3 262 1.0E-116 T 28-03-2018 IPR017627 Conserved hypothetical protein CHP03214, putative allantoin-urate catabolism protein KEGG: 00230+3.5.3.26|MetaCyc: PWY-5692|MetaCyc: PWY-5698 CO689_RS09125 b37c78c5631e47be2c57309248dd1646 80 Pfam PF09964 Uncharacterized protein conserved in bacteria (DUF2198) 5 75 3.1E-32 T 28-03-2018 IPR019242 Protein of unknown function DUF2198 CO689_RS06345 46d78de1ba7f76515806ad21110b5181 435 TIGRFAM TIGR00784 citMHS: citrate transporter 3 435 4.5E-169 T 28-03-2018 IPR014738 Citrate transporter GO:0015137|GO:0015746 CO689_RS06345 46d78de1ba7f76515806ad21110b5181 435 Pfam PF03600 Citrate transporter 14 381 9.5E-47 T 28-03-2018 IPR004680 Citrate transporter-like domain GO:0016021|GO:0055085 Reactome: R-HSA-5662702 CO689_RS06315 e6c22eb043bd8cf40a55185108620135 295 Pfam PF05853 beta-keto acid cleavage enzyme 3 288 3.0E-99 T 28-03-2018 IPR008567 3-keto-5-aminohexanoate cleavage enzyme GO:0016740|GO:0019475 KEGG: 00310+2.3.1.247|KEGG: 00600+2.3.1.24 CO689_RS06315 e6c22eb043bd8cf40a55185108620135 295 Gene3D G3DSA:3.20.20.70 1 294 1.0E-104 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CO689_RS00965 c0b6151b3a053f518ea8f62ea76fd9b0 384 PRINTS PR01270 Histone deacetylase superfamily signature 166 181 1.6E-15 T 28-03-2018 IPR000286 Histone deacetylase superfamily Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 CO689_RS00965 c0b6151b3a053f518ea8f62ea76fd9b0 384 PRINTS PR01270 Histone deacetylase superfamily signature 252 262 1.6E-15 T 28-03-2018 IPR000286 Histone deacetylase superfamily Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 CO689_RS00965 c0b6151b3a053f518ea8f62ea76fd9b0 384 PRINTS PR01270 Histone deacetylase superfamily signature 133 156 1.6E-15 T 28-03-2018 IPR000286 Histone deacetylase superfamily Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 CO689_RS00965 c0b6151b3a053f518ea8f62ea76fd9b0 384 SUPERFAMILY SSF52768 7 362 1.39E-99 T 28-03-2018 CO689_RS00965 c0b6151b3a053f518ea8f62ea76fd9b0 384 PRINTS PR01272 Acetoin utilisation ACUC protein signature 277 293 5.8E-40 T 28-03-2018 IPR003085 Acetoin utilization protein AcuC GO:0045149 CO689_RS00965 c0b6151b3a053f518ea8f62ea76fd9b0 384 PRINTS PR01272 Acetoin utilisation ACUC protein signature 316 335 5.8E-40 T 28-03-2018 IPR003085 Acetoin utilization protein AcuC GO:0045149 CO689_RS00965 c0b6151b3a053f518ea8f62ea76fd9b0 384 PRINTS PR01272 Acetoin utilisation ACUC protein signature 354 373 5.8E-40 T 28-03-2018 IPR003085 Acetoin utilization protein AcuC GO:0045149 CO689_RS00965 c0b6151b3a053f518ea8f62ea76fd9b0 384 PRINTS PR01272 Acetoin utilisation ACUC protein signature 19 39 5.8E-40 T 28-03-2018 IPR003085 Acetoin utilization protein AcuC GO:0045149 CO689_RS00965 c0b6151b3a053f518ea8f62ea76fd9b0 384 PRINTS PR01272 Acetoin utilisation ACUC protein signature 110 123 5.8E-40 T 28-03-2018 IPR003085 Acetoin utilization protein AcuC GO:0045149 CO689_RS00965 c0b6151b3a053f518ea8f62ea76fd9b0 384 PRINTS PR01272 Acetoin utilisation ACUC protein signature 89 103 5.8E-40 T 28-03-2018 IPR003085 Acetoin utilization protein AcuC GO:0045149 CO689_RS00965 c0b6151b3a053f518ea8f62ea76fd9b0 384 PRINTS PR01272 Acetoin utilisation ACUC protein signature 337 353 5.8E-40 T 28-03-2018 IPR003085 Acetoin utilization protein AcuC GO:0045149 CO689_RS00965 c0b6151b3a053f518ea8f62ea76fd9b0 384 Gene3D G3DSA:3.40.800.20 1 359 4.4E-88 T 28-03-2018 IPR023801 Histone deacetylase domain Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 CO689_RS00965 c0b6151b3a053f518ea8f62ea76fd9b0 384 Pfam PF00850 Histone deacetylase domain 25 321 2.5E-73 T 28-03-2018 IPR023801 Histone deacetylase domain Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 CO689_RS05760 598c4a1af2f9b5557bbfa20161ccb51e 142 Pfam PF13274 Protein of unknown function (DUF4065) 34 116 1.4E-5 T 28-03-2018 IPR025272 Domain of unknown function DUF4065 CO689_RS07345 3d5f2393e658ebad72d839fa0a67b7b7 374 SUPERFAMILY SSF51726 8 369 1.96E-78 T 28-03-2018 CO689_RS07345 3d5f2393e658ebad72d839fa0a67b7b7 374 Gene3D G3DSA:3.20.20.210 1 373 1.8E-97 T 28-03-2018 CO689_RS07345 3d5f2393e658ebad72d839fa0a67b7b7 374 Pfam PF01717 Cobalamin-independent synthase, Catalytic domain 164 344 3.7E-7 T 28-03-2018 IPR002629 Cobalamin-independent methionine synthase MetE, C-terminal/archaeal GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 CO689_RS05880 d3dc44d8ceec328cfc388dea0a08f894 506 Gene3D G3DSA:1.50.10.10 3 410 3.5E-19 T 28-03-2018 CO689_RS05880 d3dc44d8ceec328cfc388dea0a08f894 506 SUPERFAMILY SSF48208 220 370 1.44E-9 T 28-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 CO689_RS09860 a7c7637b1b2fdc03cbe41f101752c33e 274 Pfam PF01925 Sulfite exporter TauE/SafE 7 268 4.8E-52 T 28-03-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 CO689_RS10400 751693a0b6f03a9d88512a08f3d547ea 94 Pfam PF09683 Bacteriocin (Lactococcin_972) 31 91 2.5E-12 T 28-03-2018 IPR006540 Bacteriocin, lactococcin 972 CO689_RS10400 751693a0b6f03a9d88512a08f3d547ea 94 TIGRFAM TIGR01653 lactococcin_972: bacteriocin, lactococcin 972 family 1 91 5.1E-12 T 28-03-2018 IPR006540 Bacteriocin, lactococcin 972 CO689_RS08150 3f460debb653fd753867e7c100181e5c 221 PIRSF PIRSF000705 1 217 4.0E-63 T 28-03-2018 IPR002624 Deoxynucleoside kinase GO:0005524|GO:0006139|GO:0019206 CO689_RS08150 3f460debb653fd753867e7c100181e5c 221 Pfam PF01712 Deoxynucleoside kinase 12 211 4.9E-64 T 28-03-2018 IPR031314 Deoxynucleoside kinase domain CO689_RS08150 3f460debb653fd753867e7c100181e5c 221 Gene3D G3DSA:3.40.50.300 8 210 5.5E-44 T 28-03-2018 CO689_RS08150 3f460debb653fd753867e7c100181e5c 221 SUPERFAMILY SSF52540 11 209 5.83E-47 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CO689_RS09630 76dd189bdddff55313aa7cb59de0e816 251 Pfam PF09524 Conserved phage C-terminus (Phg_2220_C) 161 232 7.1E-33 T 28-03-2018 IPR011741 Phage conserved hypothetical protein, C-terminal CO689_RS09630 76dd189bdddff55313aa7cb59de0e816 251 TIGRFAM TIGR02220 phg_TIGR02220: phage conserved hypothetical protein, C-terminal domain 158 233 7.1E-36 T 28-03-2018 IPR011741 Phage conserved hypothetical protein, C-terminal CO689_RS08485 bf7ab3f68ef095e4b557b27dcf0d2ea7 267 Pfam PF01061 ABC-2 type transporter 17 224 6.6E-14 T 28-03-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 CO689_RS10995 7303e6dc043414d7be931af80a8dacf1 308 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 51 296 1.4E-24 T 28-03-2018 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 CO689_RS10995 7303e6dc043414d7be931af80a8dacf1 308 Gene3D G3DSA:3.20.20.190 46 308 1.1E-50 T 28-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 CO689_RS10995 7303e6dc043414d7be931af80a8dacf1 308 SUPERFAMILY SSF51695 46 302 4.97E-55 T 28-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 CO689_RS08720 5c70ed37503fe2ce2d59314e3f37f234 181 SUPERFAMILY SSF55729 2 155 9.08E-33 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CO689_RS08720 5c70ed37503fe2ce2d59314e3f37f234 181 Gene3D G3DSA:3.40.630.30 2 175 2.2E-19 T 28-03-2018 CO689_RS08720 5c70ed37503fe2ce2d59314e3f37f234 181 Pfam PF13302 Acetyltransferase (GNAT) domain 9 153 5.3E-27 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CO689_RS10405 d89ed3b3d9c311255a8e5a84aa24284f 195 Pfam PF09605 Hypothetical bacterial integral membrane protein (Trep_Strep) 8 190 4.9E-51 T 28-03-2018 IPR011733 Conserved hypothetical CHP02185, integral membrane CO689_RS10405 d89ed3b3d9c311255a8e5a84aa24284f 195 TIGRFAM TIGR02185 Trep_Strep: putative ECF transporter S component, Trep_Strep family 6 188 4.5E-29 T 28-03-2018 IPR011733 Conserved hypothetical CHP02185, integral membrane CO689_RS09310 52ccd89501975b6fbdccafd350083f3e 262 Pfam PF16228 Domain of unknown function (DUF4887) 29 170 3.1E-12 T 28-03-2018 IPR032615 Protein of unknown function DUF4887 CO689_RS01715 ad931d1742c83225b6f81f0972dd805e 358 Pfam PF03631 Virulence factor BrkB 80 333 6.7E-72 T 28-03-2018 IPR017039 Virulence factor BrkB CO689_RS01715 ad931d1742c83225b6f81f0972dd805e 358 PIRSF PIRSF035875 52 352 5.8E-101 T 28-03-2018 IPR017039 Virulence factor BrkB CO689_RS01715 ad931d1742c83225b6f81f0972dd805e 358 TIGRFAM TIGR00765 yihY_not_rbn: YihY family inner membrane protein 69 331 5.9E-56 T 28-03-2018 IPR017039 Virulence factor BrkB CO689_RS04635 a9fd60dc629bd2787f8bfca2e6dba9da 409 Pfam PF01566 Natural resistance-associated macrophage protein 47 376 1.1E-28 T 28-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 CO689_RS07410 d1301144ac288ebbf46e32263578c0e1 301 SUPERFAMILY SSF53686 4 293 1.57E-83 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CO689_RS07410 d1301144ac288ebbf46e32263578c0e1 301 Gene3D G3DSA:3.40.50.1100 17 128 7.3E-34 T 28-03-2018 CO689_RS07410 d1301144ac288ebbf46e32263578c0e1 301 Gene3D G3DSA:3.40.50.1100 129 296 5.8E-44 T 28-03-2018 CO689_RS07410 d1301144ac288ebbf46e32263578c0e1 301 ProSitePatterns PS00901 Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. 28 46 - T 28-03-2018 IPR001216 Cysteine synthase/cystathionine beta-synthase, pyridoxal-phosphate attachment site GO:0006535 CO689_RS07410 d1301144ac288ebbf46e32263578c0e1 301 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 5 282 6.5E-63 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CO689_RS07185 26211b0ac5c2747aa1e4f99547026a97 207 Gene3D G3DSA:1.20.144.10 44 191 6.3E-19 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CO689_RS07185 26211b0ac5c2747aa1e4f99547026a97 207 SUPERFAMILY SSF48317 5 192 5.1E-27 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CO689_RS07185 26211b0ac5c2747aa1e4f99547026a97 207 Pfam PF01569 PAP2 superfamily 114 185 1.8E-10 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CO689_RS07185 26211b0ac5c2747aa1e4f99547026a97 207 SMART SM00014 83 183 5.4E-11 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CO689_RS13020 93c6488d9b71b9cfabdc7d56a38f98d9 123 Pfam PF03780 Asp23 family, cell envelope-related function 12 116 1.9E-25 T 28-03-2018 IPR005531 Alkaline shock protein Asp23 CO689_RS11030 6e77ef7490c40ca97eb13c126b7e2b8c 182 Pfam PF02620 Uncharacterized ACR, COG1399 55 177 1.6E-16 T 28-03-2018 IPR003772 Large ribosomal RNA subunit accumulation protein YceD CO689_RS08730 a5ad5f464cf93d547a9917d3549482db 150 Pfam PF02639 Uncharacterized BCR, YaiI/YqxD family COG1671 17 146 3.0E-39 T 28-03-2018 IPR003791 Protein of unknown function UPF0178 CO689_RS08730 a5ad5f464cf93d547a9917d3549482db 150 Hamap MF_00489 UPF0178 protein YaiI [yaiI]. 2 148 28.339 T 28-03-2018 IPR003791 Protein of unknown function UPF0178 CO689_RS05930 d9e6eaf9c1da7d0060fd0f022dd6567a 469 Pfam PF00474 Sodium:solute symporter family 37 418 1.7E-24 T 28-03-2018 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 CO689_RS02505 3a9886dae3077cd47c0ff20f0110cd4d 144 Gene3D G3DSA:3.40.50.2300 1 138 5.1E-33 T 28-03-2018 CO689_RS02505 3a9886dae3077cd47c0ff20f0110cd4d 144 SMART SM00226 1 137 6.0E-21 T 28-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily CO689_RS02505 3a9886dae3077cd47c0ff20f0110cd4d 144 SUPERFAMILY SSF52788 2 132 9.03E-31 T 28-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily CO689_RS02505 3a9886dae3077cd47c0ff20f0110cd4d 144 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 3 131 1.7E-26 T 28-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily CO689_RS02505 3a9886dae3077cd47c0ff20f0110cd4d 144 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 3 20 2.0E-12 T 28-03-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 CO689_RS02505 3a9886dae3077cd47c0ff20f0110cd4d 144 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 109 124 2.0E-12 T 28-03-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 CO689_RS02505 3a9886dae3077cd47c0ff20f0110cd4d 144 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 71 86 2.0E-12 T 28-03-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 CO689_RS10085 38a3ba40690cb9d10e7187f5f411ce4a 187 Pfam PF09335 SNARE associated Golgi protein 34 151 2.4E-20 T 28-03-2018 IPR032816 SNARE associated Golgi protein CO689_RS13045 d251fbf8a0e89dd3bf04a49814aa765d 195 Gene3D G3DSA:1.20.5.170 3 62 1.6E-4 T 28-03-2018 CO689_RS09900 ba136415d91b489e03b9f43e83ea7413 50 Pfam PF12459 D-Ala-teichoic acid biosynthesis protein 12 50 8.5E-15 T 28-03-2018 IPR021008 Protein of unknown function DUF3687 CO689_RS02435 c656d35fc56183986afe6396234368e4 77 TIGRFAM TIGR02327 int_mem_ywzB: conserved hypothetical integral membrane protein 11 74 1.9E-16 T 28-03-2018 IPR009526 Protein of unknown function DUF1146 CO689_RS02435 c656d35fc56183986afe6396234368e4 77 Pfam PF06612 Protein of unknown function (DUF1146) 17 63 5.5E-20 T 28-03-2018 IPR009526 Protein of unknown function DUF1146 CO689_RS00305 78b3b8f610f2e0277e8ee6d2c2a5b048 226 Pfam PF02683 Cytochrome C biogenesis protein transmembrane region 8 213 1.4E-15 T 28-03-2018 IPR003834 Cytochrome C biogenesis protein, transmembrane domain GO:0016020|GO:0017004|GO:0055114 CO689_RS11745 d4e09324114effdafb445f553ae3eabc 127 Gene3D G3DSA:3.10.180.10 1 127 6.0E-13 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CO689_RS11745 d4e09324114effdafb445f553ae3eabc 127 SUPERFAMILY SSF54593 2 125 5.36E-18 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CO689_RS06510 bf1e713694ce144581b748267c1fea11 126 Pfam PF06902 Divergent 4Fe-4S mono-cluster 5 68 3.0E-26 T 28-03-2018 IPR010693 Divergent 4Fe-4S mono-cluster CO689_RS06510 bf1e713694ce144581b748267c1fea11 126 Gene3D G3DSA:3.30.70.20 11 87 0.0015 T 28-03-2018 CO689_RS03675 66f49ed214b73322ee2193da8ce892f1 409 Gene3D G3DSA:3.40.190.10 46 155 9.9E-6 T 28-03-2018 CO689_RS03675 66f49ed214b73322ee2193da8ce892f1 409 Pfam PF12698 ABC-2 family transporter protein 20 385 6.3E-45 T 28-03-2018 CO689_RS05600 9dc8183959bb4b7816f7bf093c4f389b 116 Pfam PF13273 Protein of unknown function (DUF4064) 11 93 9.2E-10 T 28-03-2018 IPR025273 Domain of unknown function DUF4064 CO689_RS09985 ce20332f04136e72b0db66ec8221f578 98 PIRSF PIRSF028784 1 94 2.2E-29 T 28-03-2018 IPR007208 Na(+)/H(+) antiporter subunit F-like GO:0015075|GO:0016021|GO:0034220 CO689_RS09985 ce20332f04136e72b0db66ec8221f578 98 Pfam PF04066 Multiple resistance and pH regulation protein F (MrpF / PhaF) 33 84 2.5E-14 T 28-03-2018 IPR007208 Na(+)/H(+) antiporter subunit F-like GO:0015075|GO:0016021|GO:0034220 CO689_RS02620 8e699cef3dc91486218f6e474e273a0b 230 SUPERFAMILY SSF55166 81 213 2.04E-38 T 28-03-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 CO689_RS02620 8e699cef3dc91486218f6e474e273a0b 230 Gene3D G3DSA:3.30.1380.10 28 217 2.1E-37 T 28-03-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 CO689_RS02620 8e699cef3dc91486218f6e474e273a0b 230 Pfam PF02557 D-alanyl-D-alanine carboxypeptidase 80 205 3.2E-43 T 28-03-2018 IPR003709 Peptidase M15B GO:0006508|GO:0008233 CO689_RS09980 d024e3efb57305d62f8ac94fd1f3290d 123 Pfam PF03334 Na+/H+ antiporter subunit 13 94 8.1E-23 T 28-03-2018 IPR005133 Na+/H+ antiporter subunit G GO:0005451|GO:0015672|GO:0015992 CO689_RS09980 d024e3efb57305d62f8ac94fd1f3290d 123 TIGRFAM TIGR01300 CPA3_mnhG_phaG: monovalent cation/proton antiporter, MnhG/PhaG subunit 13 105 2.7E-24 T 28-03-2018 IPR005133 Na+/H+ antiporter subunit G GO:0005451|GO:0015672|GO:0015992 CO689_RS03270 fb93f1c7e29445a0584ff8b246c13253 114 SUPERFAMILY SSF46785 17 112 8.44E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS03270 fb93f1c7e29445a0584ff8b246c13253 114 Gene3D G3DSA:1.10.10.10 1 114 5.3E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CO689_RS03270 fb93f1c7e29445a0584ff8b246c13253 114 TIGRFAM TIGR01889 Staph_reg_Sar: staphylococcal accessory regulator family 7 113 2.1E-24 T 28-03-2018 IPR010166 Transcriptional regulator SarA/Rot GO:0006355 CO689_RS10910 9d761005b449ba3941ff811fc87e1b98 380 Pfam PF13273 Protein of unknown function (DUF4064) 15 127 2.2E-19 T 28-03-2018 IPR025273 Domain of unknown function DUF4064 CO689_RS05465 0fa3dfa28460089ffa94d63bd2af9b8d 440 Pfam PF13520 Amino acid permease 11 409 2.9E-53 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CO689_RS05465 0fa3dfa28460089ffa94d63bd2af9b8d 440 PIRSF PIRSF006060 1 440 1.6E-78 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CO689_RS08270 a8499c511beb32c0461c61168c9c15bd 153 Pfam PF12821 Threonine/Serine exporter, ThrE 8 134 2.6E-39 T 28-03-2018 IPR024528 Threonine/Serine exporter, ThrE CO689_RS07635 13b92608264b291ff6afb10d5908e813 57 Pfam PF16882 Domain of unknown function (DUF5079) 2 49 2.1E-8 T 28-03-2018 IPR031690 Protein of unknown function DUF5079 CO689_RS00860 c0b5abf5dc711e2fa5dba354cc4234e8 257 Pfam PF01925 Sulfite exporter TauE/SafE 12 245 8.5E-41 T 28-03-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 CO689_RS12850 4358e6c47417d75cd86fb926fc54e9b6 82 SUPERFAMILY SSF54862 4 73 1.5E-13 T 28-03-2018 CO689_RS12850 4358e6c47417d75cd86fb926fc54e9b6 82 Gene3D G3DSA:3.30.70.20 2 82 1.6E-10 T 28-03-2018 CO689_RS12850 4358e6c47417d75cd86fb926fc54e9b6 82 PRINTS PR00352 3Fe-4S ferredoxin signature 7 18 1.0E-7 T 28-03-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 CO689_RS12850 4358e6c47417d75cd86fb926fc54e9b6 82 PRINTS PR00352 3Fe-4S ferredoxin signature 55 67 1.0E-7 T 28-03-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 CO689_RS12850 4358e6c47417d75cd86fb926fc54e9b6 82 PRINTS PR00352 3Fe-4S ferredoxin signature 18 28 1.0E-7 T 28-03-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 CO689_RS12850 4358e6c47417d75cd86fb926fc54e9b6 82 Pfam PF13370 4Fe-4S single cluster domain of Ferredoxin I 7 68 5.9E-21 T 28-03-2018 CO689_RS08585 eba68a0498c56e12e6162c8ee1745f7e 335 Pfam PF01384 Phosphate transporter family 22 324 5.9E-91 T 28-03-2018 IPR001204 Phosphate transporter GO:0005315|GO:0006817|GO:0016020 Reactome: R-HSA-427652 CO689_RS04120 3eba0bf096fd54b8d638cc5e5b0bb610 119 Pfam PF11345 Protein of unknown function (DUF3147) 9 117 3.6E-34 T 28-03-2018 IPR021493 Protein of unknown function DUF3147 CO689_RS00210 c53394bd4ef43c911e05243fb72d51c9 335 Pfam PF03432 Relaxase/Mobilisation nuclease domain 9 242 1.8E-80 T 28-03-2018 IPR005094 Endonuclease relaxase, MobA/VirD2 CO689_RS07360 d69c4404cbb495ce13c2b79753787ea5 267 Pfam PF13349 Putative adhesin 51 239 6.9E-23 T 28-03-2018 IPR025164 Putative adhesin CO689_RS10785 477ab5f0e4a2ded0147465c5915eb71e 191 PIRSF PIRSF037394 1 191 9.6E-57 T 28-03-2018 IPR017195 ABC-type thiamin-related transport system, permease component 1, predicted CO689_RS10785 477ab5f0e4a2ded0147465c5915eb71e 191 Pfam PF09819 ABC-type cobalt transport system, permease component 9 125 2.4E-31 T 28-03-2018 IPR017195 ABC-type thiamin-related transport system, permease component 1, predicted CO689_RS07340 07a750a2082bc6eadd467f535694b81f 156 Pfam PF04463 Protein of unknown function (DUF523) 2 144 2.5E-45 T 28-03-2018 IPR007553 Domain of unknown function DUF523 CO689_RS07340 07a750a2082bc6eadd467f535694b81f 156 ProSitePatterns PS00168 Tryptophan synthase beta chain pyridoxal-phosphate attachment site. 13 27 - T 28-03-2018 IPR006653 Tryptophan synthase, beta chain, conserved site GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 CO689_RS02480 e87995e85db397a158651d6122a303e1 116 Pfam PF03899 ATP synthase I chain 15 101 1.2E-6 T 28-03-2018 IPR005598 ATP synthase protein I CO689_RS13745 4769a8ae9392a0c802faa3724bbbb692 203 Pfam PF00293 NUDIX domain 65 200 8.4E-9 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 CO689_RS13745 4769a8ae9392a0c802faa3724bbbb692 203 Gene3D G3DSA:3.90.79.10 60 203 6.1E-9 T 28-03-2018 CO689_RS13745 4769a8ae9392a0c802faa3724bbbb692 203 SUPERFAMILY SSF55811 65 190 8.94E-14 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CO689_RS05965 5edc1f1a5b71210848d3e2c1a2e4a258 306 Pfam PF03595 Voltage-dependent anion channel 9 296 1.7E-22 T 28-03-2018 IPR004695 Voltage-dependent anion channel GO:0016021|GO:0055085 CO689_RS11385 76d54b902b633a361953724f156bf373 254 Gene3D G3DSA:3.20.20.140 1 209 1.1E-18 T 28-03-2018 CO689_RS11385 76d54b902b633a361953724f156bf373 254 PIRSF PIRSF016557 1 253 8.0E-85 T 28-03-2018 IPR016667 Capsular polysaccharide synthesis, CpsB/CapC GO:0004725|GO:0030145 CO689_RS11385 76d54b902b633a361953724f156bf373 254 SUPERFAMILY SSF89550 1 199 1.88E-13 T 28-03-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 CO689_RS03945 d3ef69c4cec88baa3604d68081053bd9 151 Pfam PF13185 GAF domain 13 128 7.6E-11 T 28-03-2018 IPR003018 GAF domain GO:0005515 CO689_RS03945 d3ef69c4cec88baa3604d68081053bd9 151 SUPERFAMILY SSF55781 12 133 2.01E-14 T 28-03-2018 IPR029016 GAF domain-like CO689_RS03945 d3ef69c4cec88baa3604d68081053bd9 151 Gene3D G3DSA:3.30.450.40 10 144 6.0E-16 T 28-03-2018 IPR029016 GAF domain-like CO689_RS05460 1623e4f333c7d78bc7355eadc9131431 512 Gene3D G3DSA:1.10.720.30 98 190 5.0E-5 T 28-03-2018 IPR003034 SAP domain CO689_RS04425 d82afb5c11484e5f57112bd74d30ae54 128 Pfam PF03788 LrgA family 20 111 2.5E-23 T 28-03-2018 IPR005538 LrgA/CidA family GO:0016021 CO689_RS10350 903f8e0a80ad2e507f88c58b698604dc 452 Pfam PF02386 Cation transport protein 29 432 2.0E-59 T 28-03-2018 IPR003445 Cation transporter GO:0006812|GO:0008324|GO:0055085 CO689_RS08330 ea49c83811d0680f96bc45d88230c71e 175 Pfam PF08741 YwhD family 10 172 7.5E-79 T 28-03-2018 IPR014852 Uncharacterised protein YwhD CO689_RS07385 0967ee2cebbee46e6b8ccd116558d449 166 Pfam PF04140 Isoprenylcysteine carboxyl methyltransferase (ICMT) family 74 164 9.1E-31 T 28-03-2018 IPR007269 Isoprenylcysteine carboxyl methyltransferase GO:0004671|GO:0006481|GO:0016021 Reactome: R-HSA-163841 CO689_RS08655 513841cb0fe02daf6bcc278bf09f1a72 269 Pfam PF06386 Gas vesicle synthesis protein GvpL/GvpF 5 266 2.6E-52 T 28-03-2018 IPR009430 Gas vesicle protein GvpL/GvpF GO:0031411|GO:0031412 CO689_RS09610 3b83d6cae28c70897b95f1e0c76b1e30 209 Pfam PF04404 ERF superfamily 10 146 1.1E-33 T 28-03-2018 IPR007499 Essential recombination function protein CO689_RS05795 8c863933b682ec9392f9976df0e2c385 282 Pfam PF02517 CAAX protease self-immunity 182 269 2.3E-14 T 28-03-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 CO689_RS05745 15252a8f8f2b754970ceda6426365d11 865 Pfam PF09586 Bacterial membrane protein YfhO 19 846 4.1E-140 T 28-03-2018 IPR018580 Uncharacterised protein family YfhO CO689_RS01750 5527a2c81d5967bd48aba6ef2d9bfb3d 328 Pfam PF06081 Aromatic acid exporter family member 1 11 149 2.6E-31 T 28-03-2018 IPR010343 Aromatic acid exporter family member 1 CO689_RS05835 7ffe309bc2a45ddd9d08aebf3decf35b 287 Pfam PF00494 Squalene/phytoene synthase 18 273 8.6E-58 T 28-03-2018 IPR002060 Squalene/phytoene synthase GO:0009058|GO:0016740 CO689_RS05835 7ffe309bc2a45ddd9d08aebf3decf35b 287 ProSitePatterns PS01044 Squalene and phytoene synthases signature 1. 130 145 - T 28-03-2018 IPR019845 Squalene/phytoene synthase, conserved site GO:0016765 Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 CO689_RS05835 7ffe309bc2a45ddd9d08aebf3decf35b 287 SUPERFAMILY SSF48576 7 283 1.73E-66 T 28-03-2018 IPR008949 Isoprenoid synthase domain CO689_RS05835 7ffe309bc2a45ddd9d08aebf3decf35b 287 Gene3D G3DSA:1.10.600.10 1 287 5.0E-74 T 28-03-2018 IPR008949 Isoprenoid synthase domain CO689_RS04760 141fa1519e1fd99852b86203233e9735 257 Pfam PF11392 Protein of unknown function (DUF2877) 155 254 3.3E-23 T 28-03-2018 IPR021530 Protein of unknown function DUF2877 CO689_RS11730 3fb6cd546175914361ac1d5e9222e3d4 94 Pfam PF04296 Protein of unknown function (DUF448) 9 83 1.8E-23 T 28-03-2018 IPR007393 Domain of unknown function DUF448 CO689_RS11730 3fb6cd546175914361ac1d5e9222e3d4 94 Gene3D G3DSA:3.30.1230.10 1 92 6.6E-26 T 28-03-2018 IPR007393 Domain of unknown function DUF448 CO689_RS11730 3fb6cd546175914361ac1d5e9222e3d4 94 SUPERFAMILY SSF64376 4 91 2.88E-25 T 28-03-2018 IPR007393 Domain of unknown function DUF448 CO689_RS00175 92113a7e7eb59f49c22859f29f28af2e 287 SUPERFAMILY SSF50494 73 260 3.35E-26 T 28-03-2018 IPR009003 Peptidase S1, PA clan CO689_RS00175 92113a7e7eb59f49c22859f29f28af2e 287 Pfam PF00089 Trypsin 76 260 2.8E-13 T 28-03-2018 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 CO689_RS00175 92113a7e7eb59f49c22859f29f28af2e 287 Gene3D G3DSA:2.40.10.10 161 265 2.4E-13 T 28-03-2018 CO689_RS00175 92113a7e7eb59f49c22859f29f28af2e 287 PRINTS PR00839 V8 serine protease family signature 240 252 6.1E-11 T 28-03-2018 IPR008256 Peptidase S1B GO:0006508|GO:0008236 CO689_RS00175 92113a7e7eb59f49c22859f29f28af2e 287 PRINTS PR00839 V8 serine protease family signature 223 239 6.1E-11 T 28-03-2018 IPR008256 Peptidase S1B GO:0006508|GO:0008236 CO689_RS00175 92113a7e7eb59f49c22859f29f28af2e 287 PRINTS PR00839 V8 serine protease family signature 84 101 6.1E-11 T 28-03-2018 IPR008256 Peptidase S1B GO:0006508|GO:0008236 CO689_RS00175 92113a7e7eb59f49c22859f29f28af2e 287 Gene3D G3DSA:2.40.10.10 26 160 1.2E-6 T 28-03-2018 CO689_RS07100 acc618426c6b108721c471634a5c9066 70 Pfam PF06107 Bacterial protein of unknown function (DUF951) 5 58 1.9E-28 T 28-03-2018 IPR009296 Protein of unknown function DUF951 CO689_RS07100 acc618426c6b108721c471634a5c9066 70 PIRSF PIRSF037263 1 65 2.8E-33 T 28-03-2018 IPR009296 Protein of unknown function DUF951 CO689_RS05430 5bee5182a1298d952b8a6caeb9de1c55 219 SUPERFAMILY SSF161098 9 203 2.22E-45 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CO689_RS05430 5bee5182a1298d952b8a6caeb9de1c55 219 Gene3D G3DSA:1.10.3720.10 2 219 8.2E-34 T 28-03-2018 CO689_RS05430 5bee5182a1298d952b8a6caeb9de1c55 219 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 33 217 2.3E-19 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CO689_RS02690 3f2859c6afb93466ac3d0ca5a9fdee37 367 Gene3D G3DSA:1.20.1070.10 100 343 1.7E-5 T 28-03-2018 CO689_RS11000 b5bbd4d34377cb626391e918c79142c3 84 Pfam PF09902 Uncharacterized protein conserved in bacteria (DUF2129) 7 76 1.3E-22 T 28-03-2018 IPR016979 Protein of unknown function DUF2129 CO689_RS11000 b5bbd4d34377cb626391e918c79142c3 84 PIRSF PIRSF031653 1 84 2.5E-25 T 28-03-2018 IPR016979 Protein of unknown function DUF2129 CO689_RS07640 7fad7ace4ab56d7faf499905339e3fb3 90 Pfam PF16882 Domain of unknown function (DUF5079) 1 84 8.1E-13 T 28-03-2018 IPR031690 Protein of unknown function DUF5079 CO689_RS08905 9b101f3709e0b49ec0b4ee67920a2461 378 Gene3D G3DSA:3.60.120.10 29 377 9.2E-94 T 28-03-2018 IPR005801 ADC synthase GO:0009058 CO689_RS08905 9b101f3709e0b49ec0b4ee67920a2461 378 PRINTS PR00095 Anthranilate synthase component I signature 221 234 2.3E-8 T 28-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CO689_RS08905 9b101f3709e0b49ec0b4ee67920a2461 378 PRINTS PR00095 Anthranilate synthase component I signature 330 344 2.3E-8 T 28-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CO689_RS08905 9b101f3709e0b49ec0b4ee67920a2461 378 PRINTS PR00095 Anthranilate synthase component I signature 315 329 2.3E-8 T 28-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CO689_RS08905 9b101f3709e0b49ec0b4ee67920a2461 378 PRINTS PR00095 Anthranilate synthase component I signature 235 248 2.3E-8 T 28-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CO689_RS08905 9b101f3709e0b49ec0b4ee67920a2461 378 Pfam PF00425 chorismate binding enzyme 117 373 1.0E-77 T 28-03-2018 IPR015890 Chorismate-utilising enzyme, C-terminal CO689_RS08905 9b101f3709e0b49ec0b4ee67920a2461 378 SUPERFAMILY SSF56322 16 376 2.75E-91 T 28-03-2018 IPR005801 ADC synthase GO:0009058 CO689_RS06255 2c0d64e577f6d7afe195d5178733408a 108 Pfam PF14470 Bacterial PH domain 11 103 4.8E-11 T 28-03-2018 CO689_RS06870 14341eecd908d1c7f61c8a0777310de9 116 Pfam PF06106 S. aureus uracil DNA glycosylase inhibitor 2 109 3.7E-34 T 28-03-2018 IPR009295 Uracil DNA glycosylase inhibitor CO689_RS12745 2a3b7e73bcd2b36d2051e55c4062632d 226 Pfam PF04298 Putative neutral zinc metallopeptidase 1 222 4.4E-91 T 28-03-2018 IPR007395 Putative neutral zinc metallopeptidase CO689_RS10675 74e42f8327630e76a09139097c88a9cf 96 TIGRFAM TIGR02901 QoxD: cytochrome aa3 quinol oxidase, subunit IV 6 91 1.3E-31 T 28-03-2018 IPR014250 Quinol oxidase subunit IV GO:0016021|GO:0016682|GO:0042773 CO689_RS10675 74e42f8327630e76a09139097c88a9cf 96 Pfam PF03626 Prokaryotic Cytochrome C oxidase subunit IV 8 81 5.8E-12 T 28-03-2018 IPR005171 Cytochrome C oxidase subunit IV, prokaryotes GO:0016021 CO689_RS13105 b7ca90be1cd47f4a18b083441fd136ae 357 Pfam PF00482 Type II secretion system (T2SS), protein F 229 348 2.5E-12 T 28-03-2018 IPR018076 Type II secretion system F domain CO689_RS03685 ca23892cd25ccb42bb73b997527641d8 240 Pfam PF11368 Protein of unknown function (DUF3169) 5 231 1.7E-24 T 28-03-2018 IPR021509 Protein of unknown function DUF3169 CO689_RS00160 23f1f5cfabf6f9390cb488c845b1f9a4 110 SUPERFAMILY SSF50118 2 104 9.16E-21 T 28-03-2018 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor CO689_RS00160 23f1f5cfabf6f9390cb488c845b1f9a4 110 Pfam PF02452 PemK-like, MazF-like toxin of type II toxin-antitoxin system 3 105 4.1E-13 T 28-03-2018 IPR003477 mRNA interferase PemK-like GO:0003677 CO689_RS00160 23f1f5cfabf6f9390cb488c845b1f9a4 110 Gene3D G3DSA:2.30.30.110 1 107 2.5E-14 T 28-03-2018 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor CO689_RS06595 3ce3b32d81ff713dfec17d819a32f8f6 193 PIRSF PIRSF000709 1 92 9.7E-8 T 28-03-2018 CO689_RS06595 3ce3b32d81ff713dfec17d819a32f8f6 193 SMART SM00855 4 154 9.5E-17 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 CO689_RS06595 3ce3b32d81ff713dfec17d819a32f8f6 193 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 5 187 9.9E-36 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 CO689_RS06595 3ce3b32d81ff713dfec17d819a32f8f6 193 SUPERFAMILY SSF53254 1 187 5.55E-41 T 28-03-2018 IPR029033 Histidine phosphatase superfamily CO689_RS06595 3ce3b32d81ff713dfec17d819a32f8f6 193 ProSitePatterns PS00175 Phosphoglycerate mutase family phosphohistidine signature. 7 16 - T 28-03-2018 IPR001345 Phosphoglycerate/bisphosphoglycerate mutase, active site GO:0003824|GO:0008152 CO689_RS06595 3ce3b32d81ff713dfec17d819a32f8f6 193 Gene3D G3DSA:3.40.50.1240 1 191 3.9E-39 T 28-03-2018 IPR029033 Histidine phosphatase superfamily CO689_RS07110 18600a4823e5294b25e99d7bd4d86ddb 111 Pfam PF13630 SdpI/YhfL protein family 25 100 6.2E-12 T 28-03-2018 IPR025962 SdpI/YhfL protein family CO689_RS07305 527703fc18a3905782503bf2f2c6212e 304 Pfam PF01925 Sulfite exporter TauE/SafE 8 246 3.9E-34 T 28-03-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 CO689_RS04190 d835be036c16886b4fdf6f5b6097f896 247 Pfam PF02517 CAAX protease self-immunity 148 238 1.7E-15 T 28-03-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 CO689_RS04670 b2a9c8e4850433262c9453446c3c3c5e 362 Pfam PF13303 Phosphotransferase system, EIIC 26 359 9.5E-90 T 28-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 CO689_RS05850 65b0296e9beb2f769366e9efca687ead 104 Gene3D G3DSA:1.20.1250.20 1 50 5.1E-4 T 28-03-2018 CO689_RS06090 8c7da09e60d84d8ae7e78000c3d51d8f 298 Pfam PF03609 PTS system sorbose-specific iic component 5 266 1.0E-65 T 28-03-2018 IPR004700 Phosphotransferase system, mannose/fructose/sorbose family, IIC subunit GO:0009401|GO:0016021 CO689_RS05625 ec6ade01243e02392f30a8cbdcadca85 522 Pfam PF03606 C4-dicarboxylate anaerobic carrier 21 518 2.8E-167 T 28-03-2018 IPR018385 C4-dicarboxylate anaerobic carrier-like GO:0016021 CO689_RS00200 3f5820f5efdf947b15a3340d3b88f6bd 127 Gene3D G3DSA:1.10.1220.10 15 57 3.9E-4 T 28-03-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 CO689_RS00200 3f5820f5efdf947b15a3340d3b88f6bd 127 Pfam PF05713 Bacterial mobilisation protein (MobC) 80 120 1.4E-6 T 28-03-2018 IPR008687 Bacterial mobilisation CO689_RS12495 3a17b270f923b891dbee56c2dd720a58 102 Pfam PF06279 Protein of unknown function (DUF1033) 4 93 3.5E-16 T 28-03-2018 IPR010434 Protein of unknown function DUF1033 CO689_RS09520 c2c3b37410f621166a6be07eb82addd8 465 TIGRFAM TIGR01980 sufB: FeS assembly protein SufB 10 456 9.3E-232 T 28-03-2018 IPR010231 SUF system FeS cluster assembly, SufB GO:0016226 CO689_RS09520 c2c3b37410f621166a6be07eb82addd8 465 Pfam PF01458 Uncharacterized protein family (UPF0051) 211 436 1.1E-76 T 28-03-2018 IPR000825 SUF system FeS cluster assembly, SufBD GO:0016226 CO689_RS09520 c2c3b37410f621166a6be07eb82addd8 465 SUPERFAMILY SSF101960 32 462 5.75E-142 T 28-03-2018 CO689_RS05470 0f85bde99f6a9557ee3d992b1d105c93 346 Gene3D G3DSA:3.40.50.1100 150 327 5.2E-45 T 28-03-2018 CO689_RS05470 0f85bde99f6a9557ee3d992b1d105c93 346 Gene3D G3DSA:3.40.50.1100 41 149 9.9E-32 T 28-03-2018 CO689_RS05470 0f85bde99f6a9557ee3d992b1d105c93 346 SUPERFAMILY SSF53686 15 330 1.44E-97 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CO689_RS05470 0f85bde99f6a9557ee3d992b1d105c93 346 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 28 319 3.4E-80 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CO689_RS05470 0f85bde99f6a9557ee3d992b1d105c93 346 TIGRFAM TIGR01127 ilvA_1Cterm: threonine ammonia-lyase 33 335 8.1E-118 T 28-03-2018 IPR005789 Threonine dehydratase, catabolic GO:0004794|GO:0006567 KEGG: 00260+4.3.1.19|KEGG: 00290+4.3.1.19 CO689_RS08405 3816d0b18db8a2eb1c754d8481ff505f 682 Pfam PF00999 Sodium/hydrogen exchanger family 10 424 1.5E-52 T 28-03-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 CO689_RS11270 dc09f5948c9c73ed67d9d0eea2fa8e5e 204 Pfam PF05103 DivIVA protein 4 133 2.6E-32 T 28-03-2018 IPR007793 DivIVA family CO689_RS11270 dc09f5948c9c73ed67d9d0eea2fa8e5e 204 TIGRFAM TIGR03544 DivI1A_domain: DivIVA domain 3 35 3.4E-6 T 28-03-2018 IPR019933 DivIVA domain CO689_RS02570 b0fcbe444a89aac77577c3fbfdf4735e 182 Pfam PF05066 HB1, ASXL, restriction endonuclease HTH domain 15 82 1.2E-10 T 28-03-2018 IPR007759 HB1/Asxl, restriction endonuclease HTH domain GO:0006351|GO:0006355 CO689_RS02570 b0fcbe444a89aac77577c3fbfdf4735e 182 Hamap MF_00357 Probable DNA-directed RNA polymerase subunit delta [rpoE]. 9 166 13.619 T 28-03-2018 IPR029757 DNA-directed RNA polymerase subunit delta GO:0006351|GO:0006355 CO689_RS02570 b0fcbe444a89aac77577c3fbfdf4735e 182 TIGRFAM TIGR04567 RNAP_delt_lowGC: DNA-directed RNA polymerase delta subunit 13 94 8.5E-30 T 28-03-2018 IPR029757 DNA-directed RNA polymerase subunit delta GO:0006351|GO:0006355 CO689_RS03855 ae3397ef1119403d29ad6377f47053e6 146 Pfam PF11070 Protein of unknown function (DUF2871) 1 129 2.8E-45 T 28-03-2018 IPR021299 Protein of unknown function DUF2871 CO689_RS10160 48acce56f17ad7bd8c7841a0726772ac 124 Pfam PF13038 Domain of unknown function (DUF3899) 33 122 3.5E-24 T 28-03-2018 IPR025007 Domain of unknown function DUF3899 CO689_RS09760 128888a958c758f77ab80d6b6ca64411 110 Pfam PF05521 Phage head-tail joining protein 9 106 2.4E-6 T 28-03-2018 IPR008767 Bacteriophage SPP1, head-tail adaptor CO689_RS13270 17e8933eea1fd79b48ef4a00747544d1 238 Gene3D G3DSA:2.40.50.140 172 238 2.0E-11 T 28-03-2018 CO689_RS06485 f7b0285d1830111835572f9171b36003 293 SUPERFAMILY SSF103481 43 142 7.32E-6 T 28-03-2018 CO689_RS06485 f7b0285d1830111835572f9171b36003 293 Pfam PF06800 Sugar transport protein 7 292 4.2E-106 T 28-03-2018 IPR010651 Sugar transport protein GO:0015144|GO:0016021|GO:0034219 CO689_RS08790 1612eca8bf0a484ef7655a4bd859ff25 205 Pfam PF07099 Protein of unknown function (DUF1361) 30 193 5.2E-30 T 28-03-2018 IPR009793 Protein of unknown function DUF1361 CO689_RS11785 373a9bf20d5f99d9d9161b2cc60b93f3 189 Gene3D G3DSA:3.10.450.40 35 91 0.0035 T 28-03-2018 CO689_RS11785 373a9bf20d5f99d9d9161b2cc60b93f3 189 Gene3D G3DSA:3.10.450.40 116 174 1.4E-7 T 28-03-2018 CO689_RS11785 373a9bf20d5f99d9d9161b2cc60b93f3 189 Pfam PF03413 Peptidase propeptide and YPEB domain 116 173 1.1E-6 T 28-03-2018 IPR025711 PepSY domain CO689_RS02730 db1d406ceb2624ba939a84c69a932f7c 310 Pfam PF07949 YbbR-like protein 229 306 1.0E-4 T 28-03-2018 IPR012505 YbbR-like CO689_RS02730 db1d406ceb2624ba939a84c69a932f7c 310 Pfam PF07949 YbbR-like protein 142 220 5.8E-7 T 28-03-2018 IPR012505 YbbR-like CO689_RS02730 db1d406ceb2624ba939a84c69a932f7c 310 Pfam PF07949 YbbR-like protein 47 127 9.3E-8 T 28-03-2018 IPR012505 YbbR-like CO689_RS11490 e2c7738acceddc0471b939232c0816bf 124 Pfam PF03780 Asp23 family, cell envelope-related function 9 116 3.0E-32 T 28-03-2018 IPR005531 Alkaline shock protein Asp23 CO689_RS01185 492ebab2fdde0eeeaf6fcaae3c5a601a 299 Pfam PF08378 Nuclease-related domain 116 171 3.4E-5 T 28-03-2018 IPR011528 Nuclease-related domain, NERD CO689_RS05185 dc04ab10c180d7903e0cd277e16ca6c9 200 Pfam PF03596 Cadmium resistance transporter 12 200 2.5E-86 T 28-03-2018 IPR004676 Cadmium resistance transporter CO689_RS05185 dc04ab10c180d7903e0cd277e16ca6c9 200 TIGRFAM TIGR00779 cad: cadmium resistance transporter family protein 12 200 3.3E-79 T 28-03-2018 IPR004676 Cadmium resistance transporter CO689_RS05845 46b56024044a331c2ce4fbd1fa6aeeb3 471 Pfam PF03606 C4-dicarboxylate anaerobic carrier 21 466 3.6E-107 T 28-03-2018 IPR018385 C4-dicarboxylate anaerobic carrier-like GO:0016021 CO689_RS13595 9f7e88d29495ffc17277c75b13fb3cf5 155 Pfam PF16284 Domain of unknown function (DUF4930) 25 152 4.4E-58 T 28-03-2018 IPR032561 Protein of unknown function DUF4930 CO689_RS07355 1a694b765c00fcff4ab539f2f4c939a2 186 Pfam PF08006 Protein of unknown function (DUF1700) 1 182 1.6E-59 T 28-03-2018 IPR012963 Protein of unknown function DUF1700 CO689_RS11150 68d8a02380b8512959fc120b2199d76c 44 Pfam PF05480 Staphylococcus haemolytic protein 1 43 1.6E-15 T 28-03-2018 IPR008846 Staphylococcal hemolytic protein family GO:0009405 CO689_RS13580 4e64b2c59ec4b11248d3dfe5c25966d9 173 TIGRFAM TIGR03426 shape_MreD: rod shape-determining protein MreD 9 157 4.0E-22 T 28-03-2018 IPR007227 Cell shape-determining protein MreD GO:0008360|GO:0016021 CO689_RS13580 4e64b2c59ec4b11248d3dfe5c25966d9 173 Pfam PF04093 rod shape-determining protein MreD 1 164 2.4E-27 T 28-03-2018 IPR007227 Cell shape-determining protein MreD GO:0008360|GO:0016021 CO689_RS09210 e9d34ca564ee5c94158d12fa1f0c64e3 81 Pfam PF05595 Domain of unknown function (DUF771) 17 80 1.3E-12 T 28-03-2018 IPR008489 Protein of unknown function DUF771 CO689_RS07275 8b855feb1a9c8f2f42a777f8fc1ead0a 198 Pfam PF11546 Staphylococcal complement inhibitor SCIN 1 108 1.1E-37 T 28-03-2018 IPR021612 Staphylococcal complement inhibitor SCIN CO689_RS05840 23a64077a4b332468f341e609b0c281b 123 Pfam PF08349 Protein of unknown function (DUF1722) 14 121 6.5E-23 T 28-03-2018 IPR013560 Domain of unknown function DUF1722 CO689_RS05630 642de513b24e3e58a4129066d86daa36 418 Pfam PF00872 Transposase, Mutator family 79 396 1.1E-31 T 28-03-2018 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 CO689_RS05610 50eee28f956a7154021f7b6b92f4b042 341 Gene3D G3DSA:2.60.40.1240 42 188 9.7E-13 T 28-03-2018 IPR029050 Immunoprotective extracellular, immunoglobulin-like domain CO689_RS06660 ffc0fd08ba6c1e63c7828a703f227a1b 404 Pfam PF14281 PD-(D/E)XK nuclease superfamily 28 202 9.4E-35 T 28-03-2018 IPR029470 PD-(D/E)XK nuclease superfamily 4 CO689_RS10600 2e3d9b89ceaf8e216dbb451aa1106744 384 Pfam PF00144 Beta-lactamase 70 358 1.6E-43 T 28-03-2018 IPR001466 Beta-lactamase-related CO689_RS10600 2e3d9b89ceaf8e216dbb451aa1106744 384 SUPERFAMILY SSF56601 67 359 3.38E-61 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CO689_RS10600 2e3d9b89ceaf8e216dbb451aa1106744 384 Gene3D G3DSA:3.40.710.10 61 377 7.4E-52 T 28-03-2018 CO689_RS08445 5a78d430950333ddb0b9a382129eddf2 250 Pfam PF13398 Peptidase M50B-like 21 241 1.8E-33 T 28-03-2018 CO689_RS09040 ab0ebe1461c7e84046b059f72047ae10 106 SUPERFAMILY SSF52833 4 90 5.98E-10 T 28-03-2018 IPR012336 Thioredoxin-like fold CO689_RS09040 ab0ebe1461c7e84046b059f72047ae10 106 Pfam PF11009 Protein of unknown function (DUF2847) 4 101 5.0E-35 T 28-03-2018 IPR022551 Protein of unknown function DUF2847 CO689_RS09040 ab0ebe1461c7e84046b059f72047ae10 106 Gene3D G3DSA:3.40.30.10 2 103 6.8E-40 T 28-03-2018 CO689_RS09040 ab0ebe1461c7e84046b059f72047ae10 106 TIGRFAM TIGR04019 B_thiol_YtxJ: bacillithiol system protein YtxJ 4 102 6.4E-36 T 28-03-2018 IPR022551 Protein of unknown function DUF2847 CO689_RS03460 247b8fb14e42009883ff907a23b17402 244 Pfam PF05257 CHAP domain 142 219 4.2E-13 T 28-03-2018 IPR007921 CHAP domain CO689_RS03460 247b8fb14e42009883ff907a23b17402 244 SUPERFAMILY SSF54001 114 243 6.96E-19 T 28-03-2018 CO689_RS10915 66540040366dbb42a2f9e28ee0315477 208 Pfam PF13273 Protein of unknown function (DUF4064) 2 96 7.0E-16 T 28-03-2018 IPR025273 Domain of unknown function DUF4064 CO689_RS09880 a50b4bbbcab986a5c64c406f0ecaaa59 97 Pfam PF11256 Protein of unknown function (DUF3055) 6 84 2.1E-32 T 28-03-2018 IPR021415 Protein of unknown function DUF3055 CO689_RS10230 8f61abfc1873c1b883fa70b7be473c1f 109 SUPERFAMILY SSF50882 13 108 7.59E-8 T 28-03-2018 IPR016085 Protease inhibitor, beta-barrel domain GO:0004866 CO689_RS10230 8f61abfc1873c1b883fa70b7be473c1f 109 Gene3D G3DSA:2.40.310.10 1 108 8.9E-42 T 28-03-2018 IPR014728 Staphostatin A/B GO:0004869|GO:0005737 CO689_RS06300 a23ee4fa87a710939e16d6131d3a01b7 86 Pfam PF02583 Metal-sensitive transcriptional repressor 5 83 8.4E-24 T 28-03-2018 IPR003735 Metal-sensitive transcriptional repressor GO:0003677|GO:0006355|GO:0046872 CO689_RS03700 582da12412b7f22b931245f30f85d8cc 167 Pfam PF05656 Protein of unknown function (DUF805) 22 159 1.1E-21 T 28-03-2018 IPR008523 Protein of unknown function DUF805 GO:0016021 CO689_RS06060 be91e450bff54b257944b07e570301a9 372 Pfam PF08808 RES domain 188 354 6.1E-18 T 28-03-2018 IPR014914 RES domain CO689_RS08710 e3397f98436448bd20f84a4c2a1be9af 126 Gene3D G3DSA:1.20.5.50 2 117 5.4E-4 T 28-03-2018 CO689_RS13680 b56975f6db062d1561c1158b19018bba 308 Pfam PF06166 Protein of unknown function (DUF979) 11 308 6.4E-114 T 28-03-2018 IPR009323 Protein of unknown function DUF979 CO689_RS05330 d1b6e8cd923e22898325e780c957e2f4 196 Pfam PF02397 Bacterial sugar transferase 8 188 8.4E-57 T 28-03-2018 IPR003362 Bacterial sugar transferase CO689_RS08650 071332f55e0fd87cc7fa9dcf4969b543 84 Pfam PF05120 Gas vesicle protein G 13 73 4.0E-11 T 28-03-2018 IPR007804 Gas vesicle protein GvpG CO689_RS10490 3c5864b1353fb6812bb398a13a2be45b 61 Pfam PF09953 Uncharacterized protein conserved in bacteria (DUF2187) 3 57 6.5E-27 T 28-03-2018 IPR018690 Protein of unknown function DUF2187 CO689_RS02630 45f1354997a30f6f37209f998b366cee 132 Pfam PF04134 Protein of unknown function, DUF393 4 109 3.2E-16 T 28-03-2018 IPR007263 Protein of unknown function DUF393 CO689_RS05940 ee56452ed53a8c39f82bd4807f1a56c8 201 Gene3D G3DSA:1.10.1660.10 1 78 1.6E-4 T 28-03-2018 CO689_RS05940 ee56452ed53a8c39f82bd4807f1a56c8 201 Pfam PF13171 Protein of unknown function (DUF4004) 4 196 1.8E-61 T 28-03-2018 IPR025063 Protein of unknown function DUF4004 CO689_RS07455 e8fd14db5eab7025407d82c4b595941c 370 Pfam PF07907 YibE/F-like protein 128 359 2.3E-66 T 28-03-2018 IPR012507 YibE/F-like CO689_RS08630 285a0405e57ac1437832e6d9e286cbce 162 Gene3D G3DSA:1.20.120.20 3 132 2.1E-4 T 28-03-2018 CO689_RS01355 8f24cb158be7e6f5d6e58891faffa03a 188 Pfam PF11667 Putative zincin peptidase 59 163 3.8E-19 T 28-03-2018 IPR021683 Putative zincin peptidase CO689_RS04110 90d17605d085800b32c432ee31812457 153 Pfam PF03788 LrgA family 32 123 3.5E-23 T 28-03-2018 IPR005538 LrgA/CidA family GO:0016021 CO689_RS06920 87dc3ae5f714a3ea2ca8fd0112799b63 444 Pfam PF07435 YycH protein 5 439 2.6E-115 T 28-03-2018 IPR009996 Regulatory protein YycH CO689_RS10470 da466f70beb6562ad06b5c0f56d52690 190 Pfam PF06338 ComK protein 3 154 2.5E-40 T 28-03-2018 IPR010461 Competence protein ComK GO:0030420 CO689_RS05015 518c6823962b2417c86c4b2ad86a908f 366 Pfam PF01757 Acyltransferase family 6 326 2.6E-24 T 28-03-2018 IPR002656 Acyltransferase 3 GO:0016747