locus-tag	class	description
MUA28_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
MUA28_RS00010	COG0592	DNA-directed DNA polymerase activity
MUA28_RS00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
MUA28_RS00025	COG0187	DNA topoisomerase II activity
MUA28_RS00035	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
MUA28_RS00040	COG2986	histidine ammonia-lyase
MUA28_RS00045	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
MUA28_RS00065	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
MUA28_RS00070	COG0359	binds to the 23S rRNA
MUA28_RS00075	COG0305	Participates in initiation and elongation during chromosome replication
MUA28_RS00085	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
MUA28_RS00100	COG0745	RESPONSE REGULATOR receiver
MUA28_RS00105	COG5002	protein histidine kinase activity
MUA28_RS00110	COG4863	YycH protein
MUA28_RS00120	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
MUA28_RS00125	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
MUA28_RS00130	COG2189	Belongs to the N(4) N(6)-methyltransferase family
MUA28_RS00135	COG3421	Type III restriction
MUA28_RS00190	COG3448	diguanylate cyclase activity
MUA28_RS00190	COG4175	Glycine betaine
MUA28_RS00195	COG1028	Short-chain dehydrogenase reductase Sdr
MUA28_RS00205	COG1280	lysine exporter protein (LysE YggA)
MUA28_RS00250	COG1705	Flagellar rod assembly protein muramidase FlgJ
MUA28_RS00250	COG3942	CHAP domain
MUA28_RS00265	COG1064	alcohol dehydrogenase
MUA28_RS00280	COG0402	S-adenosylhomocysteine deaminase activity
MUA28_RS00285	COG1686	Belongs to the peptidase S11 family
MUA28_RS00315	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
MUA28_RS00320	COG1609	Transcriptional regulator
MUA28_RS00330	COG1869	D-ribose catabolic process
MUA28_RS00350	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
MUA28_RS00360	COG0598	Magnesium transport protein CorA
MUA28_RS00365	COG0363	glucosamine-6-phosphate deaminase activity
MUA28_RS00370	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
MUA28_RS00385	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MUA28_RS00390	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MUA28_RS00395	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MUA28_RS00420	COG0778	Nitroreductase
MUA28_RS00430	COG1063	alcohol dehydrogenase
MUA28_RS00450	COG2851	Citrate transporter
MUA28_RS00465	COG2720	vancomycin resistance protein
MUA28_RS00475	COG1250	3-hydroxyacyl-CoA dehydrogenase
MUA28_RS00480	COG3246	L-lysine catabolic process to acetate
MUA28_RS00490	COG0730	response to heat
MUA28_RS00495	COG1937	Protein conserved in bacteria
MUA28_RS00500	COG2210	Belongs to the sulfur carrier protein TusA family
MUA28_RS00505	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MUA28_RS00510	COG1309	transcriptional regulator
MUA28_RS00530	COG1012	belongs to the aldehyde dehydrogenase family
MUA28_RS00545	COG0753	catalase activity
MUA28_RS00550	COG0662	Cupin 2, conserved barrel domain protein
MUA28_RS00570	COG0431	NADPH-dependent FMN reductase
MUA28_RS00570	COG1053	succinate dehydrogenase
MUA28_RS00570	COG3976	FMN-binding domain protein
MUA28_RS00605	COG2188	Transcriptional regulator
MUA28_RS00610	COG2222	sugar isomerase
MUA28_RS00620	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
MUA28_RS00620	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MUA28_RS00625	COG3715	PTS system
MUA28_RS00630	COG3716	PTS system mannose fructose sorbose family IID component
MUA28_RS00640	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
MUA28_RS00645	COG1609	Transcriptional regulator
MUA28_RS00660	COG1063	alcohol dehydrogenase
MUA28_RS00685	COG3181	Tripartite tricarboxylate transporter family receptor
MUA28_RS00700	COG1966	Carbon starvation protein
MUA28_RS00705	COG1054	Belongs to the UPF0176 family
MUA28_RS00710	COG2388	GCN5-related N-acetyl-transferase
MUA28_RS00725	COG2388	GCN5-related N-acetyl-transferase
MUA28_RS00730	COG0346	lactoylglutathione lyase activity
MUA28_RS00735	COG0789	Transcriptional regulator
MUA28_RS00740	COG1664	Polymer-forming cytoskeletal
MUA28_RS00750	COG0006	proline dipeptidase activity
MUA28_RS00760	COG0477	Major facilitator Superfamily
MUA28_RS00770	COG0667	Aldo Keto reductase
MUA28_RS00790	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
MUA28_RS00815	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MUA28_RS00820	COG1028	Short-chain dehydrogenase reductase Sdr
MUA28_RS00830	COG1288	antiporter activity
MUA28_RS00845	COG3871	stress protein (general stress protein 26)
MUA28_RS00850	COG1929	Belongs to the glycerate kinase type-1 family
MUA28_RS00865	COG0579	oxidoreductase
MUA28_RS00875	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MUA28_RS00880	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
MUA28_RS00890	COG1757	Na H antiporter
MUA28_RS00905	COG4195	phage-related replication protein
MUA28_RS00935	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
MUA28_RS00950	COG1609	Transcriptional regulator
MUA28_RS00950	COG2207	Transcriptional regulator
MUA28_RS01025	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
MUA28_RS01035	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MUA28_RS01050	COG1288	antiporter activity
MUA28_RS01055	COG0549	Belongs to the carbamate kinase family
MUA28_RS01060	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
MUA28_RS01085	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MUA28_RS01115	COG0706	membrane insertase activity
MUA28_RS01130	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
MUA28_RS01135	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
MUA28_RS01165	COG4221	oxidoreductase activity
MUA28_RS01170	COG0069	glutamate synthase activity
MUA28_RS01175	COG4336	lyase activity
MUA28_RS01205	COG0531	amino acid
MUA28_RS01215	COG0753	catalase activity
MUA28_RS01220	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
MUA28_RS01240	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MUA28_RS01245	COG2011	ABC-type metal ion transport system permease component
MUA28_RS01250	COG1464	Belongs to the NlpA lipoprotein family
MUA28_RS01290	COG2210	Belongs to the sulfur carrier protein TusA family
MUA28_RS01300	COG3961	Belongs to the TPP enzyme family
MUA28_RS01305	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
MUA28_RS01310	COG1510	regulation of RNA biosynthetic process
MUA28_RS01315	COG1012	belongs to the aldehyde dehydrogenase family
MUA28_RS01320	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
MUA28_RS01325	COG3583	domain protein
MUA28_RS01325	COG3583	domain protein
MUA28_RS01335	COG1181	Belongs to the D-alanine--D-alanine ligase family
MUA28_RS01345	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
MUA28_RS01380	COG0438	transferase activity, transferring glycosyl groups
MUA28_RS01385	COG0463	Glycosyl transferase, family 2
MUA28_RS01385	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
MUA28_RS01395	COG0494	nUDIX hydrolase
MUA28_RS01415	COG3588	fructose-bisphosphate aldolase
MUA28_RS01420	COG2258	MOSC domain
MUA28_RS01450	COG1012	belongs to the aldehyde dehydrogenase family
MUA28_RS01450	COG1454	alcohol dehydrogenase
MUA28_RS01460	COG0640	Transcriptional regulator
MUA28_RS01470	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
MUA28_RS01480	COG1737	Transcriptional regulator
MUA28_RS01495	COG0640	Transcriptional regulator
MUA28_RS01510	COG1131	(ABC) transporter
MUA28_RS01540	COG0582	viral genome integration into host DNA
MUA28_RS01545	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
MUA28_RS01545	COG2111	Na H antiporter
MUA28_RS01550	COG2111	Na H antiporter
MUA28_RS01555	COG1006	Multisubunit Na H antiporter MnhC subunit
MUA28_RS01565	COG1863	multisubunit Na H antiporter MnhE subunit
MUA28_RS01570	COG2212	antiporter activity
MUA28_RS01575	COG1320	monovalent cation:proton antiporter activity
MUA28_RS01585	COG1113	amino acid transport
MUA28_RS01600	COG1131	(ABC) transporter
MUA28_RS01610	COG2824	Alkylphosphonate utilization operon protein PhnA
MUA28_RS01620	COG2376	Dihydroxyacetone kinase
MUA28_RS01625	COG1461	Dihydroxyacetone kinase
MUA28_RS01630	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
MUA28_RS01635	COG1216	Glycosyl transferase, family 2
MUA28_RS01635	COG1442	glycosyl transferase family 8
MUA28_RS01640	COG1215	transferase activity, transferring glycosyl groups
MUA28_RS01640	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
MUA28_RS01645	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
MUA28_RS01660	COG0531	amino acid
MUA28_RS01675	COG0463	Glycosyl transferase, family 2
MUA28_RS01695	COG0446	pyridine nucleotide-disulphide oxidoreductase
MUA28_RS01700	COG1131	(ABC) transporter
MUA28_RS01730	COG0318	PFAM AMP-dependent synthetase and ligase
MUA28_RS01735	COG0183	Belongs to the thiolase family
MUA28_RS01745	COG2235	arginine
MUA28_RS01755	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
MUA28_RS01760	COG1438	arginine binding
MUA28_RS01765	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
MUA28_RS01770	COG2022	thiamine diphosphate biosynthetic process
MUA28_RS01780	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MUA28_RS01785	COG0352	thiamine-phosphate diphosphorylase activity
MUA28_RS01800	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
MUA28_RS01815	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
MUA28_RS01825	COG1131	(ABC) transporter
MUA28_RS01840	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
MUA28_RS01845	COG2508	Transcriptional regulator
MUA28_RS01850	COG1953	Uracil, thiamine, allantoin
MUA28_RS01855	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
MUA28_RS01870	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
MUA28_RS01875	COG3257	ureidoglycine aminohydrolase activity
MUA28_RS01880	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
MUA28_RS01885	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
MUA28_RS01890	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
MUA28_RS01895	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
MUA28_RS01910	COG2807	transmembrane transport
MUA28_RS01915	COG5646	InterPro IPR014922
MUA28_RS01920	COG2207	Transcriptional regulator
MUA28_RS01935	COG2211	Major facilitator Superfamily
MUA28_RS01940	COG1904	glucuronate isomerase
MUA28_RS01945	COG1312	Catalyzes the dehydration of D-mannonate
MUA28_RS01950	COG1028	Short-chain dehydrogenase reductase Sdr
MUA28_RS01955	COG3250	beta-galactosidase activity
MUA28_RS01975	COG1518	maintenance of DNA repeat elements
MUA28_RS02000	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
MUA28_RS02005	COG1984	allophanate hydrolase subunit 2
MUA28_RS02010	COG0511	ligase activity, forming carbon-carbon bonds
MUA28_RS02015	COG0439	Biotin carboxylase
MUA28_RS02020	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
MUA28_RS02025	COG1914	H( )-stimulated, divalent metal cation uptake system
MUA28_RS02030	COG1070	Carbohydrate kinase
MUA28_RS02045	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
MUA28_RS02055	COG1695	Transcriptional regulator
MUA28_RS02100	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
MUA28_RS02120	COG3189	MarR family transcriptional regulator
MUA28_RS02125	COG1882	Formate acetyltransferase
MUA28_RS02140	COG0604	alcohol dehydrogenase
MUA28_RS02140	COG3321	synthase
MUA28_RS02150	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
MUA28_RS02160	COG3001	Fructosamine kinase
MUA28_RS02175	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
MUA28_RS02190	COG3764	Sortase (surface protein transpeptidase)
MUA28_RS02195	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
MUA28_RS02200	COG4932	domain protein
MUA28_RS02200	COG3266	domain, Protein
MUA28_RS02200	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
MUA28_RS02205	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
MUA28_RS02225	COG1136	(ABC) transporter
MUA28_RS02230	COG0577	efflux transmembrane transporter activity
MUA28_RS02235	COG0583	DNA-binding transcription factor activity
MUA28_RS02240	COG1388	LysM domain
MUA28_RS02245	COG1380	Effector of murein hydrolase LrgA
MUA28_RS02255	COG0028	Belongs to the TPP enzyme family
MUA28_RS02270	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
MUA28_RS02275	COG1687	branched-chain amino acid
MUA28_RS02280	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
MUA28_RS02290	COG1609	Transcriptional regulator
MUA28_RS02305	COG1760	l-serine dehydratase
MUA28_RS02310	COG1760	l-serine dehydratase
MUA28_RS02320	COG2249	NAD(P)H dehydrogenase (quinone) activity
MUA28_RS02325	COG0778	Nitroreductase
MUA28_RS02330	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MUA28_RS02335	COG1132	(ABC) transporter
MUA28_RS02340	COG1132	(ABC) transporter
MUA28_RS02355	COG0346	lactoylglutathione lyase activity
MUA28_RS02360	COG2211	Major facilitator Superfamily
MUA28_RS02365	COG2207	Transcriptional regulator
MUA28_RS02370	COG3250	beta-galactosidase activity
MUA28_RS02375	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
MUA28_RS02380	COG1129	ABC transporter
MUA28_RS02390	COG0586	Pfam SNARE associated Golgi protein
MUA28_RS02395	COG2271	Major facilitator Superfamily
MUA28_RS02405	COG3527	Alpha-acetolactate decarboxylase
MUA28_RS02410	COG1289	transmembrane transporter activity
MUA28_RS02415	COG4876	unkown
MUA28_RS02420	COG0523	cobalamin synthesis protein
MUA28_RS02425	COG2357	RelA SpoT domain protein
MUA28_RS02435	COG1802	Transcriptional regulator
MUA28_RS02445	COG2610	gluconate transmembrane transporter activity
MUA28_RS02460	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
MUA28_RS02490	COG4619	ABC transporter
MUA28_RS02495	COG0390	transport system, permease component
MUA28_RS02500	COG2814	Major facilitator Superfamily
MUA28_RS02505	COG2272	Belongs to the type-B carboxylesterase lipase family
MUA28_RS02510	COG0531	amino acid
MUA28_RS02515	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
MUA28_RS02525	COG1174	glycine betaine transport
MUA28_RS02535	COG1174	glycine betaine transport
MUA28_RS02550	COG1309	transcriptional regulator
MUA28_RS02565	COG1346	cytolysis
MUA28_RS02570	COG1380	Effector of murein hydrolase LrgA
MUA28_RS02575	COG3279	Response regulator of the LytR AlgR family
MUA28_RS02580	COG3275	phosphorelay sensor kinase activity
MUA28_RS02590	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
MUA28_RS02600	COG1113	amino acid transport
MUA28_RS02610	COG2814	Major facilitator Superfamily
MUA28_RS02620	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MUA28_RS02625	COG0588	phosphoglycerate mutase activity
MUA28_RS02635	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MUA28_RS02640	COG0765	amino acid transport
MUA28_RS02645	COG1126	abc transporter atp-binding protein
MUA28_RS02685	COG2116	formate transmembrane transporter activity
MUA28_RS02700	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
MUA28_RS02710	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
MUA28_RS02710	COG1648	precorrin-2 dehydrogenase activity
MUA28_RS02715	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
MUA28_RS02720	COG1140	nitrate reductase beta subunit
MUA28_RS02730	COG2181	nitrate reductase activity
MUA28_RS02740	COG4585	Histidine kinase
MUA28_RS02745	COG2197	response regulator
MUA28_RS02750	COG2223	nitrite transmembrane transporter activity
MUA28_RS02755	COG0772	Belongs to the SEDS family
MUA28_RS02760	COG3425	synthase
MUA28_RS02780	COG1846	Transcriptional regulator
MUA28_RS02785	COG0778	Nitroreductase
MUA28_RS02795	COG0697	spore germination
MUA28_RS02800	COG1301	dicarboxylic acid transport
MUA28_RS02810	COG1611	Belongs to the LOG family
MUA28_RS02830	COG0492	ferredoxin-NADP+ reductase activity
MUA28_RS02835	COG2814	Major facilitator Superfamily
MUA28_RS02840	COG0604	alcohol dehydrogenase
MUA28_RS02855	COG1620	l-lactate permease
MUA28_RS02860	COG0438	transferase activity, transferring glycosyl groups
MUA28_RS02870	COG3850	Histidine kinase
MUA28_RS02870	COG5002	protein histidine kinase activity
MUA28_RS02875	COG0745	RESPONSE REGULATOR receiver
MUA28_RS02880	COG0577	efflux transmembrane transporter activity
MUA28_RS02905	COG2814	Major facilitator Superfamily
MUA28_RS02915	COG1566	PFAM secretion protein HlyD family protein
MUA28_RS02920	COG2814	Major facilitator Superfamily
MUA28_RS02925	COG1033	growth of symbiont in host cell
MUA28_RS02925	COG2409	Drug exporters of the RND superfamily
MUA28_RS02930	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
MUA28_RS02935	COG3314	Sporulation integral membrane protein YlbJ
MUA28_RS02955	COG0598	Magnesium transport protein CorA
MUA28_RS02960	COG1304	FMN binding
MUA28_RS02975	COG0602	queuosine metabolic process
MUA28_RS02980	COG2094	Belongs to the DNA glycosylase MPG family
MUA28_RS02985	COG3152	Membrane
MUA28_RS03005	COG4152	abc transporter atp-binding protein
MUA28_RS03010	COG1668	transmembrane transport
MUA28_RS03015	COG1742	UPF0060 membrane protein
MUA28_RS03020	COG2017	converts alpha-aldose to the beta-anomer
MUA28_RS03030	COG1266	CAAX protease self-immunity
MUA28_RS03035	COG0010	Belongs to the arginase family
MUA28_RS03040	COG0583	DNA-binding transcription factor activity
MUA28_RS03045	COG3314	Sporulation integral membrane protein YlbJ
MUA28_RS03050	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
MUA28_RS03055	COG1228	amidohydrolase
MUA28_RS03060	COG0659	secondary active sulfate transmembrane transporter activity
MUA28_RS03065	COG1473	amidohydrolase
MUA28_RS03070	COG1028	Short-chain dehydrogenase reductase Sdr
MUA28_RS03075	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
MUA28_RS03090	COG2271	Major facilitator Superfamily
MUA28_RS03100	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
MUA28_RS03125	COG1113	amino acid transport
MUA28_RS03130	COG1737	Transcriptional regulator
MUA28_RS03155	COG1316	TRANSCRIPTIONal
MUA28_RS03165	COG3383	formate dehydrogenase (NAD+) activity
MUA28_RS03190	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MUA28_RS03195	COG2076	Multidrug Resistance protein
MUA28_RS03200	COG2076	Multidrug Resistance protein
MUA28_RS03215	COG1757	Na H antiporter
MUA28_RS03225	COG3942	CHAP domain
MUA28_RS03265	COG0829	nickel cation binding
MUA28_RS03275	COG0830	nickel cation binding
MUA28_RS03280	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
MUA28_RS03285	COG0804	urea catabolic process
MUA28_RS03290	COG0832	Belongs to the urease beta subunit family
MUA28_RS03295	COG0831	urea catabolic process
MUA28_RS03305	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
MUA28_RS03310	COG1960	acyl-CoA dehydrogenase activity
MUA28_RS03315	COG1957	nucleoside hydrolase
MUA28_RS03320	COG1268	BioY protein
MUA28_RS03330	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
MUA28_RS03335	COG1609	Transcriptional regulator
MUA28_RS03340	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
MUA28_RS03345	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
MUA28_RS03350	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
MUA28_RS03355	COG0725	ABC transporter, periplasmic molybdate-binding protein
MUA28_RS03360	COG4149	molybdate abc transporter
MUA28_RS03365	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
MUA28_RS03370	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
MUA28_RS03375	COG0521	Mo-molybdopterin cofactor biosynthetic process
MUA28_RS03380	COG0315	cyclic pyranopterin monophosphate synthase activity
MUA28_RS03385	COG0303	'Molybdopterin
MUA28_RS03395	COG0314	molybdopterin synthase activity
MUA28_RS03405	COG0746	molybdenum cofactor guanylyltransferase activity
MUA28_RS03410	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
MUA28_RS03420	COG1131	(ABC) transporter
MUA28_RS03425	COG0842	Transport permease protein
MUA28_RS03435	COG2197	response regulator
MUA28_RS03440	COG2814	Major facilitator Superfamily
MUA28_RS03460	COG2348	transferase activity, transferring amino-acyl groups
MUA28_RS03465	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MUA28_RS03485	COG4975	Glucose uptake
MUA28_RS03500	COG2252	PERMEase
MUA28_RS03515	COG0051	transcription antitermination factor activity, RNA binding
MUA28_RS03520	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
MUA28_RS03525	COG0088	Forms part of the polypeptide exit tunnel
MUA28_RS03530	COG0089	rRNA binding
MUA28_RS03535	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
MUA28_RS03540	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
MUA28_RS03545	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
MUA28_RS03550	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
MUA28_RS03555	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
MUA28_RS03565	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
MUA28_RS03570	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
MUA28_RS03575	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
MUA28_RS03580	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
MUA28_RS03585	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MUA28_RS03590	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
MUA28_RS03595	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
MUA28_RS03600	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
MUA28_RS03605	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
MUA28_RS03610	COG1841	ribosomal large subunit assembly
MUA28_RS03615	COG0200	Binds to the 23S rRNA
MUA28_RS03620	COG0201	protein transport
MUA28_RS03625	COG0563	adenylate kinase activity
MUA28_RS03635	COG0257	Belongs to the bacterial ribosomal protein bL36 family
MUA28_RS03640	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
MUA28_RS03645	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
MUA28_RS03650	COG0202	RNA polymerase activity
MUA28_RS03655	COG0203	ribosomal protein L17
MUA28_RS03675	COG0101	tRNA pseudouridine synthase activity
MUA28_RS03680	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
MUA28_RS03685	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
MUA28_RS03690	COG1442	glycosyl transferase family 8
MUA28_RS03715	COG2213	PTS system mannitol-specific
MUA28_RS03715	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
MUA28_RS03720	COG3775	system Galactitol-specific IIC component
MUA28_RS03735	COG2318	DinB family
MUA28_RS03740	COG2608	mercury ion transmembrane transporter activity
MUA28_RS03750	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
MUA28_RS03755	COG0574	Belongs to the PEP-utilizing enzyme family
MUA28_RS03755	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MUA28_RS03760	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
MUA28_RS03765	COG2130	NADP-dependent
MUA28_RS03775	COG2130	NADP-dependent
MUA28_RS03780	COG0604	alcohol dehydrogenase
MUA28_RS03785	COG0604	alcohol dehydrogenase
MUA28_RS03790	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
MUA28_RS03805	COG1302	Protein conserved in bacteria
MUA28_RS03815	COG2814	Major facilitator Superfamily
MUA28_RS03820	COG4264	IucA IucC family
MUA28_RS03825	COG3457	Alanine racemase
MUA28_RS03830	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
MUA28_RS03835	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MUA28_RS03840	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MUA28_RS03845	COG3314	Sporulation integral membrane protein YlbJ
MUA28_RS03850	COG2329	Antibiotic biosynthesis monooxygenase
MUA28_RS03865	COG1988	membrane-bound metal-dependent
MUA28_RS03870	COG4284	Utp--glucose-1-phosphate uridylyltransferase
MUA28_RS03875	COG1272	protein, Hemolysin III
MUA28_RS03890	COG2814	Major facilitator Superfamily
MUA28_RS03895	COG0489	protein tyrosine kinase activity
MUA28_RS03945	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
MUA28_RS03950	COG4856	YbbR-like protein
MUA28_RS03955	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MUA28_RS03960	COG0246	Mannitol dehydrogenase
MUA28_RS03965	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
MUA28_RS03970	COG3711	transcriptional antiterminator
MUA28_RS03985	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
MUA28_RS04010	COG0640	Transcriptional regulator
MUA28_RS04015	COG0702	epimerase
MUA28_RS04020	COG2186	Transcriptional regulator
MUA28_RS04025	COG0247	lactate metabolic process
MUA28_RS04030	COG1139	Iron-sulfur cluster binding protein
MUA28_RS04035	COG1556	Lactate utilization protein
MUA28_RS04040	COG1482	cell wall glycoprotein biosynthetic process
MUA28_RS04060	COG0783	Belongs to the Dps family
MUA28_RS04065	COG1876	peptidase activity
MUA28_RS04070	COG0813	purine-nucleoside phosphorylase activity
MUA28_RS04075	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
MUA28_RS04085	COG1854	S-ribosylhomocysteine lyase activity
MUA28_RS04115	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MUA28_RS04120	COG3343	RNA polymerase activity
MUA28_RS04125	COG0504	CTP synthase activity
MUA28_RS04135	COG0191	fructose-bisphosphate aldolase activity
MUA28_RS04140	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MUA28_RS04145	COG1733	regulation of RNA biosynthetic process
MUA28_RS04150	COG1012	belongs to the aldehyde dehydrogenase family
MUA28_RS04155	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
MUA28_RS04160	COG0254	rRNA binding
MUA28_RS04165	COG1435	thymidine kinase activity
MUA28_RS04170	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
MUA28_RS04175	COG2890	protein-(glutamine-N5) methyltransferase activity
MUA28_RS04180	COG0009	L-threonylcarbamoyladenylate synthase
MUA28_RS04185	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MUA28_RS04190	COG4475	Protein of unknown function (DUF436)
MUA28_RS04195	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
MUA28_RS04200	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
MUA28_RS04205	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
MUA28_RS04215	COG0356	it plays a direct role in the translocation of protons across the membrane
MUA28_RS04220	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MUA28_RS04225	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
MUA28_RS04230	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MUA28_RS04235	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
MUA28_RS04240	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
MUA28_RS04245	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
MUA28_RS04250	COG0355	proton-transporting ATP synthase activity, rotational mechanism
MUA28_RS04255	COG4836	Membrane
MUA28_RS04260	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MUA28_RS04265	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
MUA28_RS04275	COG0629	single-stranded DNA binding
MUA28_RS04280	COG1388	LysM domain
MUA28_RS04295	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
MUA28_RS04305	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
MUA28_RS04310	COG0352	thiamine-phosphate diphosphorylase activity
MUA28_RS04315	COG0706	membrane insertase activity
MUA28_RS04320	COG0456	acetyltransferase
MUA28_RS04325	COG1418	mRNA catabolic process
MUA28_RS04330	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MUA28_RS04335	COG1937	Protein conserved in bacteria
MUA28_RS04350	COG2217	Heavy metal translocating P-type atpase
MUA28_RS04360	COG0772	Belongs to the SEDS family
MUA28_RS04365	COG1181	Belongs to the D-alanine--D-alanine ligase family
MUA28_RS04370	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
MUA28_RS04375	COG0513	Belongs to the DEAD box helicase family
MUA28_RS04390	COG3402	PFAM membrane-flanked domain
MUA28_RS04395	COG0736	holo-[acyl-carrier-protein] synthase activity
MUA28_RS04400	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MUA28_RS04415	COG2208	phosphoserine phosphatase activity
MUA28_RS04430	COG1191	sigma factor activity
MUA28_RS04435	COG2183	response to ionizing radiation
MUA28_RS04440	COG3091	SprT-like family
MUA28_RS04465	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
MUA28_RS04475	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
MUA28_RS04480	COG0473	3-isopropylmalate dehydrogenase activity
MUA28_RS04485	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
MUA28_RS04490	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
MUA28_RS04500	COG0028	Belongs to the TPP enzyme family
MUA28_RS04505	COG0129	dihydroxy-acid dehydratase activity
MUA28_RS04510	COG0802	atpase or kinase
MUA28_RS04515	COG1214	PFAM Peptidase M22, glycoprotease
MUA28_RS04520	COG0456	acetyltransferase
MUA28_RS04525	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
MUA28_RS04530	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
MUA28_RS04535	COG0488	(ABC) transporter
MUA28_RS04540	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
MUA28_RS04545	COG0425	Belongs to the sulfur carrier protein TusA family
MUA28_RS04550	COG2391	methyltransferase activity
MUA28_RS04555	COG1621	beta-fructofuranosidase activity
MUA28_RS04575	COG4512	PFAM Accessory gene regulator B
MUA28_RS04600	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
MUA28_RS04605	COG0459	protein refolding
MUA28_RS04625	COG1725	Transcriptional regulator
MUA28_RS04640	COG1131	(ABC) transporter
MUA28_RS04670	COG1136	(ABC) transporter
MUA28_RS04695	COG2706	6-phosphogluconolactonase activity
MUA28_RS04700	COG0471	metal ion transport
MUA28_RS04710	COG1335	isochorismatase
MUA28_RS04715	COG1227	inorganic diphosphatase activity
MUA28_RS04720	COG1012	belongs to the aldehyde dehydrogenase family
MUA28_RS04725	COG0077	Prephenate dehydratase
MUA28_RS04735	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
MUA28_RS04740	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
MUA28_RS04745	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
MUA28_RS04755	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
MUA28_RS04760	COG4496	protein, YerC YecD
MUA28_RS04765	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
MUA28_RS04775	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
MUA28_RS04780	COG4851	CamS sex pheromone cAM373 precursor
MUA28_RS04790	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MUA28_RS04795	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MUA28_RS04800	COG0154	amidase activity
MUA28_RS04805	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MUA28_RS04810	COG1597	lipid kinase activity
MUA28_RS04815	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MUA28_RS04825	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MUA28_RS04845	COG4129	membrane
MUA28_RS04850	COG0024	Methionine aminopeptidase
MUA28_RS04870	COG2197	response regulator
MUA28_RS04875	COG0288	reversible hydration of carbon dioxide
MUA28_RS04880	COG1295	ribonuclease BN
MUA28_RS04895	COG4840	Belongs to the UPF0435 family
MUA28_RS04900	COG2309	aminopeptidase activity
MUA28_RS04905	COG1607	acyl-coa hydrolase
MUA28_RS04910	COG0535	radical SAM domain protein
MUA28_RS04920	COG0693	protein deglycase activity
MUA28_RS04925	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
MUA28_RS04930	COG2137	regulation of response to DNA damage stimulus
MUA28_RS04940	COG1388	LysM domain
MUA28_RS04940	COG1134	teichoic acid transport
MUA28_RS04950	COG1988	membrane-bound metal-dependent
MUA28_RS04960	COG3557	Belongs to the UPF0374 family
MUA28_RS04970	COG4129	membrane
MUA28_RS04975	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
MUA28_RS04980	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
MUA28_RS04985	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MUA28_RS04990	COG0735	belongs to the Fur family
MUA28_RS05155	COG0765	amino acid transport
MUA28_RS05160	COG1126	abc transporter atp-binding protein
MUA28_RS05165	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
MUA28_RS05170	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
MUA28_RS05180	COG0363	glucosamine-6-phosphate deaminase activity
MUA28_RS05190	COG0114	fumarate hydratase activity
MUA28_RS05195	COG0564	pseudouridine synthase activity
MUA28_RS05200	COG2203	Gaf domain
MUA28_RS05200	COG4585	Histidine kinase
MUA28_RS05205	COG2197	response regulator
MUA28_RS05220	COG4399	Belongs to the UPF0754 family
MUA28_RS05230	COG0420	3'-5' exonuclease activity
MUA28_RS05240	COG3481	metal-dependent phosphohydrolase, HD sub domain
MUA28_RS05245	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
MUA28_RS05265	COG0537	adenosine 5'-monophosphoramidase activity
MUA28_RS05270	COG1131	(ABC) transporter
MUA28_RS05285	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
MUA28_RS05290	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
MUA28_RS05295	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
MUA28_RS05310	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
MUA28_RS05315	COG0157	Belongs to the NadC ModD family
MUA28_RS05320	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
MUA28_RS05330	COG1827	regulation of RNA biosynthetic process
MUA28_RS05375	COG0582	viral genome integration into host DNA
MUA28_RS05510	COG0756	dUTP diphosphatase activity
MUA28_RS05520	COG1396	sequence-specific DNA binding
MUA28_RS05595	COG0740	serine-type endopeptidase activity
MUA28_RS05645	COG5280	Phage tail tape measure protein TP901
MUA28_RS05645	COG3953	SLT domain
MUA28_RS05685	COG0860	N-Acetylmuramoyl-L-alanine amidase
MUA28_RS05685	COG1388	LysM domain
MUA28_RS05720	COG0318	PFAM AMP-dependent synthetase and ligase
MUA28_RS05730	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
MUA28_RS05735	COG0494	nUDIX hydrolase
MUA28_RS05740	COG1506	peptidase
MUA28_RS05745	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
MUA28_RS05750	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
MUA28_RS05760	COG0656	L-ascorbic acid biosynthetic process
MUA28_RS05765	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MUA28_RS05780	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
MUA28_RS05795	COG1595	DNA-templated transcription, initiation
MUA28_RS05805	COG3266	domain, Protein
MUA28_RS05805	COG4193	domain, Protein
MUA28_RS05805	COG5632	N-Acetylmuramoyl-L-alanine amidase
MUA28_RS05815	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
MUA28_RS05815	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
MUA28_RS05820	COG0307	riboflavin synthase, alpha
MUA28_RS05830	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
MUA28_RS05835	COG0506	proline dehydrogenase activity
MUA28_RS05840	COG2267	carboxylic ester hydrolase activity
MUA28_RS05845	COG0039	L-malate dehydrogenase activity
MUA28_RS05855	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
MUA28_RS05860	COG1242	4 iron, 4 sulfur cluster binding
MUA28_RS05865	COG2814	Major facilitator Superfamily
MUA28_RS05875	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MUA28_RS05880	COG2081	HI0933 family
MUA28_RS05885	COG2244	polysaccharide biosynthetic process
MUA28_RS05890	COG1187	pseudouridine synthase activity
MUA28_RS05900	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
MUA28_RS05910	COG0510	thiamine kinase activity
MUA28_RS05915	COG0220	tRNA (guanine-N7-)-methyltransferase activity
MUA28_RS05920	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MUA28_RS05930	COG1363	Peptidase, m42
MUA28_RS05935	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MUA28_RS05940	COG4848	Belongs to the UPF0354 family
MUA28_RS05945	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MUA28_RS05950	COG1674	ftsk spoiiie
MUA28_RS05955	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
MUA28_RS05960	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
MUA28_RS05970	COG1605	Chorismate mutase
MUA28_RS05970	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
MUA28_RS05975	COG1609	Transcriptional regulator
MUA28_RS05985	COG0454	-acetyltransferase
MUA28_RS05990	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
MUA28_RS05995	COG2759	Belongs to the formate--tetrahydrofolate ligase family
MUA28_RS06005	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
MUA28_RS06010	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MUA28_RS06015	COG0204	Acyl-transferase
MUA28_RS06020	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MUA28_RS06020	COG1263	PTS System
MUA28_RS06030	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
MUA28_RS06035	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
MUA28_RS06040	COG1764	response to oxidative stress
MUA28_RS06045	COG0584	glycerophosphoryl diester phosphodiesterase
MUA28_RS06060	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
MUA28_RS06065	COG1956	GAF domain-containing protein
MUA28_RS06070	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
MUA28_RS06075	COG1104	cysteine desulfurase activity
MUA28_RS06080	COG0301	tRNA thio-modification
MUA28_RS06085	COG0730	response to heat
MUA28_RS06095	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
MUA28_RS06100	COG0827	DNA restriction-modification system
MUA28_RS06105	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MUA28_RS06110	COG0589	response to stress
MUA28_RS06120	COG0006	proline dipeptidase activity
MUA28_RS06125	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
MUA28_RS06135	COG4109	DRTGG domain
MUA28_RS06140	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
MUA28_RS06145	COG0587	DNA-directed DNA polymerase activity
MUA28_RS06150	COG0281	malic enzyme
MUA28_RS06155	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
MUA28_RS06160	COG0825	malonyl-CoA metabolic process
MUA28_RS06165	COG0205	6-phosphofructokinase activity
MUA28_RS06170	COG0469	pyruvate kinase activity
MUA28_RS06175	COG1113	amino acid transport
MUA28_RS06180	COG0372	Belongs to the citrate synthase family
MUA28_RS06185	COG0538	isocitrate dehydrogenase activity
MUA28_RS06190	COG0745	RESPONSE REGULATOR receiver
MUA28_RS06195	COG5002	protein histidine kinase activity
MUA28_RS06200	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MUA28_RS06200	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MUA28_RS06210	COG0237	dephospho-CoA kinase activity
MUA28_RS06220	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
MUA28_RS06230	COG1484	DNA-dependent DNA replication
MUA28_RS06235	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
MUA28_RS06240	COG0833	amino acid
MUA28_RS06245	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
MUA28_RS06250	COG0291	Belongs to the bacterial ribosomal protein bL35 family
MUA28_RS06255	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
MUA28_RS06260	COG4112	unkown
MUA28_RS06270	COG0544	peptidyl-prolyl cis-trans isomerase activity
MUA28_RS06275	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
MUA28_RS06280	COG0218	Necessary for normal cell division and for the maintenance of normal septation
MUA28_RS06285	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
MUA28_RS06290	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
MUA28_RS06295	COG0181	hydroxymethylbilane synthase activity
MUA28_RS06310	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
MUA28_RS06320	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
MUA28_RS06335	COG2818	Glycosylase
MUA28_RS06340	COG0525	valine-tRNA ligase activity
MUA28_RS06345	COG0285	dihydrofolate synthase activity
MUA28_RS06350	COG2003	Belongs to the UPF0758 family
MUA28_RS06385	COG2868	ribosomal protein
MUA28_RS06395	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
MUA28_RS06400	COG4492	Belongs to the UPF0735 family
MUA28_RS06405	COG0632	four-way junction helicase activity
MUA28_RS06410	COG2255	four-way junction helicase activity
MUA28_RS06420	COG0343	queuine tRNA-ribosyltransferase activity
MUA28_RS06425	COG1862	Preprotein translocase
MUA28_RS06430	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
MUA28_RS06430	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
MUA28_RS06435	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
MUA28_RS06435	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
MUA28_RS06440	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
MUA28_RS06450	COG1490	D-aminoacyl-tRNA deacylase activity
MUA28_RS06455	COG0860	N-Acetylmuramoyl-L-alanine amidase
MUA28_RS06460	COG0124	histidyl-tRNA synthetase
MUA28_RS06465	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
MUA28_RS06475	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
MUA28_RS06480	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
MUA28_RS06485	COG1959	2 iron, 2 sulfur cluster binding
MUA28_RS06495	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MUA28_RS06500	COG1104	cysteine desulfurase activity
MUA28_RS06505	COG0482	sulfurtransferase activity
MUA28_RS06515	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
MUA28_RS06520	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
MUA28_RS06525	COG4472	Bacterial protein of unknown function (DUF965)
MUA28_RS06530	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
MUA28_RS06540	COG4122	O-methyltransferase activity
MUA28_RS06545	COG0826	peptidase U32
MUA28_RS06550	COG0826	peptidase U32
MUA28_RS06555	COG0572	uridine kinase
MUA28_RS06560	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
MUA28_RS06565	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
MUA28_RS06570	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
MUA28_RS06575	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
MUA28_RS06580	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
MUA28_RS06585	COG1534	Rna-binding protein
MUA28_RS06595	COG1713	HD superfamily hydrolase involved in NAD metabolism
MUA28_RS06600	COG0799	negative regulation of ribosome biogenesis
MUA28_RS06610	COG1555	photosystem II stabilization
MUA28_RS06610	COG1596	polysaccharide export
MUA28_RS06615	COG2131	deaminase
MUA28_RS06620	COG0658	competence protein
MUA28_RS06620	COG2333	competence protein COMEC
MUA28_RS06630	COG0268	Binds directly to 16S ribosomal RNA
MUA28_RS06635	COG0481	GTPase activity
MUA28_RS06640	COG0635	Involved in the biosynthesis of porphyrin-containing compound
MUA28_RS06645	COG1420	regulation of RNA biosynthetic process
MUA28_RS06650	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
MUA28_RS06655	COG0443	Heat shock 70 kDa protein
MUA28_RS06660	COG0484	heat shock protein binding
MUA28_RS06665	COG2264	protein methyltransferase activity
MUA28_RS06670	COG1385	rRNA (uridine-N3-)-methyltransferase activity
MUA28_RS06675	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
MUA28_RS06690	COG4864	UPF0365 protein
MUA28_RS06700	COG1702	phosphate starvation-inducible protein PhoH
MUA28_RS06705	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
MUA28_RS06710	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
MUA28_RS06720	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
MUA28_RS06725	COG1381	Involved in DNA repair and RecF pathway recombination
MUA28_RS06730	COG0423	glycine-tRNA ligase activity
MUA28_RS06735	COG0517	IMP dehydrogenase activity
MUA28_RS06740	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
MUA28_RS06750	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MUA28_RS06755	COG2384	SAM-dependent methyltransferase
MUA28_RS06765	COG0513	Belongs to the DEAD box helicase family
MUA28_RS06770	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
MUA28_RS06775	COG1121	(ABC) transporter
MUA28_RS06780	COG1108	ABC-type Mn2 Zn2 transport systems permease components
MUA28_RS06785	COG0735	belongs to the Fur family
MUA28_RS06795	COG0768	penicillin binding
MUA28_RS06800	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
MUA28_RS06810	COG4483	Protein conserved in bacteria
MUA28_RS06815	COG1940	carbohydrate kinase activity
MUA28_RS06820	COG0011	TIGRFAM Protein of
MUA28_RS06825	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MUA28_RS06830	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
MUA28_RS06835	COG1459	type II secretion system
MUA28_RS06855	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
MUA28_RS06860	COG0404	The glycine cleavage system catalyzes the degradation of glycine
MUA28_RS06865	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
MUA28_RS06870	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
MUA28_RS06875	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MUA28_RS06880	COG0095	Lipoate-protein ligase
MUA28_RS06895	COG0006	proline dipeptidase activity
MUA28_RS06900	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
MUA28_RS06905	COG0511	ligase activity, forming carbon-carbon bonds
MUA28_RS06910	COG0439	Biotin carboxylase
MUA28_RS06920	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MUA28_RS06925	COG1570	exodeoxyribonuclease VII activity
MUA28_RS06930	COG1722	exodeoxyribonuclease VII activity
MUA28_RS06940	COG1438	arginine binding
MUA28_RS06945	COG0497	DNA recombination
MUA28_RS06950	COG0280	phosphate acetyltransferase
MUA28_RS06955	COG3426	butyrate kinase activity
MUA28_RS06960	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MUA28_RS06965	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
MUA28_RS06970	COG0022	dehydrogenase e1 component
MUA28_RS06975	COG0508	dehydrogenase complex catalyzes the overall conversion of
MUA28_RS06985	COG4129	membrane
MUA28_RS06990	COG2195	Cleaves the N-terminal amino acid of tripeptides
MUA28_RS07005	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
MUA28_RS07010	COG1234	tRNA 3'-trailer cleavage
MUA28_RS07015	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MUA28_RS07025	COG0667	Aldo Keto reductase
MUA28_RS07035	COG0735	belongs to the Fur family
MUA28_RS07040	COG4974	Belongs to the 'phage' integrase family
MUA28_RS07050	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
MUA28_RS07055	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
MUA28_RS07060	COG1187	pseudouridine synthase activity
MUA28_RS07065	COG0745	RESPONSE REGULATOR receiver
MUA28_RS07080	COG1141	Ferredoxin
MUA28_RS07090	COG0514	ATP-dependent DNA helicase (RecQ)
MUA28_RS07100	COG0492	ferredoxin-NADP+ reductase activity
MUA28_RS07110	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
MUA28_RS07120	COG1160	GTP binding
MUA28_RS07125	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
MUA28_RS07140	COG2226	methyltransferase
MUA28_RS07145	COG0142	geranyltranstransferase activity
MUA28_RS07150	COG0105	UTP biosynthetic process
MUA28_RS07155	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
MUA28_RS07160	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
MUA28_RS07165	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
MUA28_RS07175	COG5582	Belongs to the UPF0302 family
MUA28_RS07180	COG4347	Protein of unknown function (DUF1405)
MUA28_RS07185	COG2738	Putative neutral zinc metallopeptidase
MUA28_RS07190	COG1694	Mazg nucleotide pyrophosphohydrolase
MUA28_RS07195	COG0438	transferase activity, transferring glycosyl groups
MUA28_RS07200	COG0617	tRNA 3'-terminal CCA addition
MUA28_RS07210	COG1199	ATP-dependent helicase activity
MUA28_RS07210	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
MUA28_RS07215	COG0017	Asparaginyl-tRNA synthetase
MUA28_RS07220	COG3935	DnaD domain protein
MUA28_RS07225	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
MUA28_RS07235	COG4499	WXG100 protein secretion system (Wss), protein YukC
MUA28_RS07235	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
MUA28_RS07240	COG3331	DNA recombination
MUA28_RS07250	COG4474	Belongs to the UPF0398 family
MUA28_RS07255	COG3599	regulation of cell shape
MUA28_RS07265	COG0116	Belongs to the methyltransferase superfamily
MUA28_RS07270	COG2962	Rard protein
MUA28_RS07275	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
MUA28_RS07280	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MUA28_RS07285	COG0328	RNA-DNA hybrid ribonuclease activity
MUA28_RS07290	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
MUA28_RS07300	COG1413	lyase activity
MUA28_RS07330	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MUA28_RS07335	COG2190	(PTS) system
MUA28_RS07345	COG0793	Belongs to the peptidase S41A family
MUA28_RS07355	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
MUA28_RS07360	COG0671	phosphoesterase, PA-phosphatase related
MUA28_RS07370	COG0745	RESPONSE REGULATOR receiver
MUA28_RS07375	COG5002	protein histidine kinase activity
MUA28_RS07380	COG0567	Dehydrogenase, E1 component
MUA28_RS07405	COG0714	Associated with various cellular activities
MUA28_RS07410	COG4548	von Willebrand factor, type A
MUA28_RS07415	COG1114	Component of the transport system for branched-chain amino acids
MUA28_RS07420	COG1597	lipid kinase activity
MUA28_RS07425	COG3853	Toxic anion resistance protein (TelA)
MUA28_RS07445	COG1278	Cold shock
MUA28_RS07460	COG1473	amidohydrolase
MUA28_RS07470	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
MUA28_RS07475	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MUA28_RS07480	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
MUA28_RS07485	COG0527	aspartate kinase activity
MUA28_RS07490	COG0488	(ABC) transporter
MUA28_RS07495	COG2996	Protein conserved in bacteria
MUA28_RS07500	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
MUA28_RS07505	COG0573	inorganic phosphate transmembrane transporter activity
MUA28_RS07510	COG0581	inorganic phosphate transmembrane transporter activity
MUA28_RS07515	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
MUA28_RS07520	COG0704	Plays a role in the regulation of phosphate uptake
MUA28_RS07525	COG1164	Oligoendopeptidase f
MUA28_RS07535	COG0747	negative chemotaxis
MUA28_RS07565	COG2348	transferase activity, transferring amino-acyl groups
MUA28_RS07570	COG2348	transferase activity, transferring amino-acyl groups
MUA28_RS07575	COG0159	tryptophan synthase activity
MUA28_RS07580	COG0133	tryptophan synthase activity
MUA28_RS07585	COG0135	phosphoribosylanthranilate isomerase activity
MUA28_RS07590	COG0134	indole-3-glycerol-phosphate synthase activity
MUA28_RS07595	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
MUA28_RS07600	COG0512	Glutamine amidotransferase of anthranilate synthase
MUA28_RS07605	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
MUA28_RS07610	COG1363	Peptidase, m42
MUA28_RS07615	COG0287	Prephenate dehydrogenase
MUA28_RS07620	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MUA28_RS07640	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
MUA28_RS07655	COG0628	permease
MUA28_RS07660	COG1263	PTS System
MUA28_RS07660	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MUA28_RS07660	COG2190	(PTS) system
MUA28_RS07665	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MUA28_RS07665	COG2190	(PTS) system
MUA28_RS07665	COG1263	PTS System
MUA28_RS07670	COG3711	transcriptional antiterminator
MUA28_RS07675	COG1115	amino acid carrier protein
MUA28_RS07680	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MUA28_RS07695	COG4841	protein insertion into membrane
MUA28_RS07705	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
MUA28_RS07710	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
MUA28_RS07715	COG1970	mechanosensitive ion channel activity
MUA28_RS07725	COG0420	3'-5' exonuclease activity
MUA28_RS07730	COG4846	Membrane protein involved in cytochrome C biogenesis
MUA28_RS07735	COG3763	UPF0154 protein
MUA28_RS07740	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
MUA28_RS07745	COG4224	UPF0291 protein
MUA28_RS07755	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
MUA28_RS07765	COG2249	NAD(P)H dehydrogenase (quinone) activity
MUA28_RS07775	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MUA28_RS07780	COG1621	beta-fructofuranosidase activity
MUA28_RS07785	COG1609	Transcriptional regulator
MUA28_RS07790	COG2340	Cysteine-rich secretory protein family
MUA28_RS07795	COG0516	GMP reductase activity
MUA28_RS07800	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MUA28_RS07810	COG0833	amino acid
MUA28_RS07825	COG0083	homoserine kinase activity
MUA28_RS07830	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
MUA28_RS07835	COG0460	homoserine dehydrogenase
MUA28_RS07840	COG0527	aspartate kinase activity
MUA28_RS07865	COG1525	nuclease
MUA28_RS07875	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MUA28_RS07880	COG0789	Transcriptional regulator
MUA28_RS07890	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
MUA28_RS07895	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
MUA28_RS07900	COG0386	Belongs to the glutathione peroxidase family
MUA28_RS08010	COG1783	phage Terminase large subunit
MUA28_RS08045	COG0756	dUTP diphosphatase activity
MUA28_RS08110	COG1484	DNA-dependent DNA replication
MUA28_RS08170	COG3645	SOS response
MUA28_RS08170	COG3646	Phage regulatory protein
MUA28_RS08200	COG0582	viral genome integration into host DNA
MUA28_RS08205	COG1923	regulation of RNA biosynthetic process
MUA28_RS08210	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
MUA28_RS08220	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
MUA28_RS08225	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
MUA28_RS08230	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
MUA28_RS08245	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
MUA28_RS08250	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
MUA28_RS08255	COG0584	glycerophosphoryl diester phosphodiesterase
MUA28_RS08265	COG4550	Control of competence regulator ComK, YlbF/YmcA
MUA28_RS08270	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
MUA28_RS08275	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MUA28_RS08280	COG0601	transmembrane transport
MUA28_RS08285	COG4608	Belongs to the ABC transporter superfamily
MUA28_RS08290	COG0444	Belongs to the ABC transporter superfamily
MUA28_RS08295	COG0747	negative chemotaxis
MUA28_RS08310	COG1013	pyruvate-flavodoxin oxidoreductase activity
MUA28_RS08315	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
MUA28_RS08315	COG0674	pyruvate-flavodoxin oxidoreductase activity
MUA28_RS08320	COG1692	metallophosphoesterase
MUA28_RS08330	COG0583	DNA-binding transcription factor activity
MUA28_RS08340	COG1418	mRNA catabolic process
MUA28_RS08345	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
MUA28_RS08350	COG1058	Belongs to the CinA family
MUA28_RS08350	COG1546	Belongs to the CinA family
MUA28_RS08370	COG0300	oxidoreductase activity
MUA28_RS08375	COG0612	Peptidase, M16
MUA28_RS08380	COG0612	Peptidase, M16
MUA28_RS08385	COG2188	Transcriptional regulator
MUA28_RS08395	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MUA28_RS08400	COG1185	polyribonucleotide nucleotidyltransferase activity
MUA28_RS08405	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
MUA28_RS08410	COG0196	riboflavin kinase activity
MUA28_RS08415	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
MUA28_RS08425	COG3850	Histidine kinase
MUA28_RS08425	COG5002	protein histidine kinase activity
MUA28_RS08430	COG0745	RESPONSE REGULATOR receiver
MUA28_RS08445	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
MUA28_RS08455	COG0584	glycerophosphoryl diester phosphodiesterase
MUA28_RS08465	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
MUA28_RS08470	COG1358	cellular component organization or biogenesis
MUA28_RS08475	COG2740	Nucleic-acid-binding protein implicated in transcription termination
MUA28_RS08480	COG0195	Participates in both transcription termination and antitermination
MUA28_RS08485	COG0779	Required for maturation of 30S ribosomal subunits
MUA28_RS08495	COG0442	prolyl-tRNA aminoacylation
MUA28_RS08505	COG4589	Belongs to the CDS family
MUA28_RS08515	COG0233	cytoplasmic translational termination
MUA28_RS08520	COG0528	UMP kinase activity
MUA28_RS08530	COG0052	Belongs to the universal ribosomal protein uS2 family
MUA28_RS08535	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
MUA28_RS08540	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
MUA28_RS08545	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
MUA28_RS08550	COG4974	Belongs to the 'phage' integrase family
MUA28_RS08555	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
MUA28_RS08560	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MUA28_RS08565	COG0758	DNA mediated transformation
MUA28_RS08570	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
MUA28_RS08575	COG0045	succinate-CoA ligase (ADP-forming) activity
MUA28_RS08580	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MUA28_RS08595	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
MUA28_RS08600	COG4485	Bacterial membrane protein, YfhO
MUA28_RS08615	COG0335	large ribosomal subunit rRNA binding
MUA28_RS08620	COG0336	Belongs to the RNA methyltransferase TrmD family
MUA28_RS08625	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
MUA28_RS08630	COG0228	four-way junction DNA binding
MUA28_RS08635	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
MUA28_RS08640	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
MUA28_RS08645	COG0552	protein localization to endoplasmic reticulum
MUA28_RS08650	COG1196	nuclear chromosome segregation
MUA28_RS08655	COG0571	ribonuclease III activity
MUA28_RS08660	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
MUA28_RS08675	COG0416	fatty acid biosynthetic process
MUA28_RS08680	COG1349	DNA-binding transcription factor activity
MUA28_RS08690	COG1760	l-serine dehydratase
MUA28_RS08695	COG1760	l-serine dehydratase
MUA28_RS08700	COG1461	Dihydroxyacetone kinase
MUA28_RS08705	COG1302	Protein conserved in bacteria
MUA28_RS08715	COG1564	THIamine pyrophosphokinase
MUA28_RS08720	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
MUA28_RS08725	COG1162	GTPase activity
MUA28_RS08735	COG0631	protein serine/threonine phosphatase activity
MUA28_RS08740	COG0820	rRNA (adenine-C2-)-methyltransferase activity
MUA28_RS08745	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
MUA28_RS08745	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MUA28_RS08750	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
MUA28_RS08770	COG2910	NAD(P)H-binding
MUA28_RS08775	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MUA28_RS08780	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
MUA28_RS08790	COG1758	RNA polymerase activity
MUA28_RS08795	COG0194	GDP metabolic process
MUA28_RS08810	COG1316	TRANSCRIPTIONal
MUA28_RS08815	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
MUA28_RS08820	COG0110	maltose O-acetyltransferase activity
MUA28_RS08825	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
MUA28_RS08850	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
MUA28_RS08850	COG0463	Glycosyl transferase, family 2
MUA28_RS08855	COG0297	glycogen (starch) synthase activity
MUA28_RS08860	COG1045	serine acetyltransferase
MUA28_RS08900	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
MUA28_RS08905	COG0284	orotidine-5'-phosphate decarboxylase activity
MUA28_RS08910	COG0167	dihydroorotate dehydrogenase activity
MUA28_RS08915	COG0543	2 iron, 2 sulfur cluster binding
MUA28_RS08920	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
MUA28_RS08925	COG0505	Belongs to the CarA family
MUA28_RS08935	COG0540	Belongs to the ATCase OTCase family
MUA28_RS08945	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
MUA28_RS08960	COG1518	maintenance of DNA repeat elements
MUA28_RS08975	COG0564	pseudouridine synthase activity
MUA28_RS08980	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
MUA28_RS08990	COG2514	catechol 2,3-dioxygenase activity
MUA28_RS08995	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
MUA28_RS09000	COG3599	regulation of cell shape
MUA28_RS09010	COG0762	integral membrane protein
MUA28_RS09015	COG1799	cell septum assembly
MUA28_RS09020	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
MUA28_RS09035	COG0849	cell division
MUA28_RS09045	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
MUA28_RS09050	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MUA28_RS09055	COG0768	penicillin binding
MUA28_RS09060	COG4839	cell division protein FtsL
MUA28_RS09065	COG0275	rRNA processing
MUA28_RS09070	COG2001	Belongs to the MraZ family
MUA28_RS09075	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
MUA28_RS09080	COG0454	-acetyltransferase
MUA28_RS09085	COG1011	Hydrolase
MUA28_RS09115	COG2176	DNA-directed DNA polymerase activity
MUA28_RS09130	COG0346	lactoylglutathione lyase activity
MUA28_RS09145	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
MUA28_RS09155	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
MUA28_RS09160	COG1053	succinate dehydrogenase
MUA28_RS09165	COG2009	succinate dehydrogenase
MUA28_RS09170	COG0322	excinuclease ABC activity
MUA28_RS09175	COG3118	belongs to the thioredoxin family
MUA28_RS09180	COG1193	negative regulation of DNA recombination
MUA28_RS09185	COG1796	DNA polymerase
MUA28_RS09185	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
MUA28_RS09200	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MUA28_RS09210	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
MUA28_RS09215	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MUA28_RS09220	COG0333	Belongs to the bacterial ribosomal protein bL32 family
MUA28_RS09230	COG1323	Belongs to the UPF0348 family
MUA28_RS09240	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
MUA28_RS09245	COG0742	ribosomal rna small subunit methyltransferase
MUA28_RS09260	COG0584	glycerophosphoryl diester phosphodiesterase
MUA28_RS09265	COG3679	Belongs to the UPF0342 family
MUA28_RS09280	COG0109	protoheme IX farnesyltransferase activity
MUA28_RS09285	COG1612	heme a metabolic process
MUA28_RS09295	COG0772	Belongs to the SEDS family
MUA28_RS09300	COG4838	Belongs to the UPF0358 family
MUA28_RS09305	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
MUA28_RS09315	COG1217	gtp-binding protein TYPA
MUA28_RS09325	COG0483	inositol monophosphate 1-phosphatase activity
MUA28_RS09330	COG4493	Belongs to the UPF0637 family
MUA28_RS09335	COG1914	H( )-stimulated, divalent metal cation uptake system
MUA28_RS09355	COG1177	transmembrane transport
MUA28_RS09360	COG1176	ABC-type spermidine putrescine transport system, permease component I
MUA28_RS09375	COG4476	Belongs to the UPF0223 family
MUA28_RS09405	COG0242	peptide deformylase activity
MUA28_RS09415	COG5503	Protein of unknown function (DUF1447)
MUA28_RS09425	COG0569	domain protein
MUA28_RS09430	COG1294	oxidase, subunit
MUA28_RS09435	COG1271	oxidase subunit
MUA28_RS09445	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MUA28_RS09460	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
MUA28_RS09475	COG1122	ATPase activity
MUA28_RS09480	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MUA28_RS09490	COG0151	Belongs to the GarS family
MUA28_RS09495	COG0138	bifunctional purine biosynthesis protein purh
MUA28_RS09505	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
MUA28_RS09510	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
MUA28_RS09515	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MUA28_RS09520	COG0047	phosphoribosylformylglycinamidine synthase activity
MUA28_RS09525	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MUA28_RS09530	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
MUA28_RS09535	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
MUA28_RS09540	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
MUA28_RS09545	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
MUA28_RS09555	COG1363	Peptidase, m42
MUA28_RS09560	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
MUA28_RS09560	COG1017	nitric oxide dioxygenase activity
MUA28_RS09570	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
MUA28_RS09580	COG1845	cytochrome c oxidase, subunit III
MUA28_RS09585	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
MUA28_RS09595	COG1349	DNA-binding transcription factor activity
MUA28_RS09605	COG0698	ribose 5-phosphate isomerase
MUA28_RS09610	COG1105	Belongs to the carbohydrate kinase PfkB family
MUA28_RS09630	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MUA28_RS09635	COG2723	6-phospho-beta-galactosidase activity
MUA28_RS09640	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
MUA28_RS09640	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
MUA28_RS09645	COG1447	Phosphotransferase system cellobiose-specific component IIA
MUA28_RS09665	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MUA28_RS09670	COG1959	2 iron, 2 sulfur cluster binding
MUA28_RS09680	COG1316	TRANSCRIPTIONal
MUA28_RS09705	COG3594	Acyltransferase
MUA28_RS09710	COG0436	Aminotransferase
MUA28_RS09720	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
MUA28_RS09725	COG0596	Alpha beta hydrolase
MUA28_RS09730	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
MUA28_RS09735	COG1169	isochorismate synthase
MUA28_RS09740	COG1575	Belongs to the MenA family. Type 1 subfamily
MUA28_RS09750	COG2314	TM2 domain
MUA28_RS09770	COG4873	Protein conserved in bacteria
MUA28_RS09805	COG4509	Sortase family
MUA28_RS09810	COG1120	ATPase activity
MUA28_RS09840	COG1129	ABC transporter
MUA28_RS09865	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
MUA28_RS09870	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
MUA28_RS09875	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
MUA28_RS09880	COG0131	Imidazoleglycerol-phosphate dehydratase
MUA28_RS09890	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
MUA28_RS09895	COG0107	imidazoleglycerol-phosphate synthase activity
MUA28_RS09900	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
MUA28_RS09900	COG0140	phosphoribosyl-ATP diphosphatase activity
MUA28_RS09905	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
MUA28_RS09910	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MUA28_RS09915	COG0861	Integral membrane protein TerC family
MUA28_RS09920	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
MUA28_RS09935	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
MUA28_RS09940	COG2814	Major facilitator Superfamily
MUA28_RS09945	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
MUA28_RS09950	COG2382	esterase
MUA28_RS09955	COG1115	amino acid carrier protein
MUA28_RS09960	COG0628	permease
MUA28_RS09965	COG2814	Major facilitator Superfamily
MUA28_RS09975	COG0475	glutathione-regulated potassium exporter activity
MUA28_RS09975	COG0569	domain protein
MUA28_RS09980	COG2239	Acts as a magnesium transporter
MUA28_RS09985	COG0564	pseudouridine synthase activity
MUA28_RS09990	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MUA28_RS09995	COG2357	RelA SpoT domain protein
MUA28_RS10005	COG4116	CYTH
MUA28_RS10010	COG2346	COG2346, Truncated hemoglobins
MUA28_RS10030	COG1164	Oligoendopeptidase f
MUA28_RS10035	COG4862	establishment of competence for transformation
MUA28_RS10040	COG1393	Belongs to the ArsC family
MUA28_RS10045	COG0180	Tryptophanyl-tRNA synthetase
MUA28_RS10055	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
MUA28_RS10060	COG0454	-acetyltransferase
MUA28_RS10065	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MUA28_RS10070	COG4166	transmembrane transport
MUA28_RS10075	COG4608	Belongs to the ABC transporter superfamily
MUA28_RS10080	COG0444	Belongs to the ABC transporter superfamily
MUA28_RS10085	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MUA28_RS10090	COG0601	transmembrane transport
MUA28_RS10105	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MUA28_RS10130	COG0561	phosphatase activity
MUA28_RS10150	COG1074	ATP-dependent DNA helicase activity
MUA28_RS10155	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
MUA28_RS10170	COG0398	Pfam SNARE associated Golgi protein
MUA28_RS10175	COG0166	Belongs to the GPI family
MUA28_RS10180	COG0137	argininosuccinate synthase activity
MUA28_RS10185	COG0165	Argininosuccinate lyase
MUA28_RS10200	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
MUA28_RS10205	COG1012	belongs to the aldehyde dehydrogenase family
MUA28_RS10210	COG1902	pentaerythritol trinitrate reductase activity
MUA28_RS10215	COG1098	S1 RNA binding domain
MUA28_RS10235	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MUA28_RS10245	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
MUA28_RS10245	COG2111	Na H antiporter
MUA28_RS10250	COG2111	Na H antiporter
MUA28_RS10255	COG1006	Multisubunit Na H antiporter MnhC subunit
MUA28_RS10260	COG0651	ATP synthesis coupled electron transport
MUA28_RS10265	COG1863	multisubunit Na H antiporter MnhE subunit
MUA28_RS10270	COG2212	antiporter activity
MUA28_RS10290	COG2050	protein possibly involved in aromatic compounds catabolism
MUA28_RS10295	COG2056	Na+-H+ antiporter family
MUA28_RS10300	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
MUA28_RS10305	COG1252	NADH dehydrogenase
MUA28_RS10310	COG0316	Belongs to the HesB IscA family
MUA28_RS10315	COG4844	belongs to the
MUA28_RS10320	COG1252	NADH dehydrogenase
MUA28_RS10325	COG4837	Protein of unknown function (DUF1462)
MUA28_RS10330	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
MUA28_RS10335	COG0789	Transcriptional regulator
MUA28_RS10340	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
MUA28_RS10345	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
MUA28_RS10350	COG1696	Membrane protein involved in D-alanine export
MUA28_RS10355	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MUA28_RS10365	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MUA28_RS10370	COG0647	UMP catabolic process
MUA28_RS10375	COG2445	Protein of unknown function DUF86
MUA28_RS10385	COG4470	Protein conserved in bacteria
MUA28_RS10390	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
MUA28_RS10395	COG0737	Belongs to the 5'-nucleotidase family
MUA28_RS10400	COG0730	response to heat
MUA28_RS10405	COG1801	Protein of unknown function DUF72
MUA28_RS10415	COG1253	flavin adenine dinucleotide binding
MUA28_RS10430	COG0822	iron-sulfur transferase activity
MUA28_RS10440	COG0719	Fe-S assembly protein
MUA28_RS10445	COG0396	ATPase activity
MUA28_RS10450	COG1464	Belongs to the NlpA lipoprotein family
MUA28_RS10455	COG2011	ABC-type metal ion transport system permease component
MUA28_RS10460	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MUA28_RS10465	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MUA28_RS10470	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
MUA28_RS10475	COG0509	glycine decarboxylation via glycine cleavage system
MUA28_RS10480	COG1393	Belongs to the ArsC family
MUA28_RS10485	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MUA28_RS10495	COG0710	3-dehydroquinate dehydratase activity
MUA28_RS10515	COG1704	LemA family
MUA28_RS10520	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
MUA28_RS10530	COG1278	Cold shock
MUA28_RS10535	COG0300	oxidoreductase activity
MUA28_RS10540	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
MUA28_RS10570	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
MUA28_RS10575	COG0557	exoribonuclease II activity
MUA28_RS10580	COG1647	Serine aminopeptidase, S33
MUA28_RS10585	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
MUA28_RS10595	COG0148	phosphopyruvate hydratase activity
MUA28_RS10600	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
MUA28_RS10610	COG0126	phosphoglycerate kinase activity
MUA28_RS10640	COG0740	serine-type endopeptidase activity
MUA28_RS10715	COG3620	sequence-specific DNA binding
MUA28_RS10720	COG1396	sequence-specific DNA binding
MUA28_RS10740	COG1114	Component of the transport system for branched-chain amino acids
MUA28_RS10745	COG2814	Major facilitator Superfamily
MUA28_RS10750	COG1481	regulation of sporulation
MUA28_RS10755	COG0391	Required for morphogenesis under gluconeogenic growth conditions
MUA28_RS10760	COG1660	Displays ATPase and GTPase activities
MUA28_RS10775	COG0110	maltose O-acetyltransferase activity
MUA28_RS10780	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
MUA28_RS10785	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
MUA28_RS10790	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
MUA28_RS10810	COG3942	CHAP domain
MUA28_RS10820	COG0653	protein targeting
MUA28_RS10825	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
MUA28_RS10830	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
MUA28_RS10835	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
MUA28_RS10845	COG1739	Uncharacterized protein family UPF0029
MUA28_RS10855	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MUA28_RS10860	COG2199	diguanylate cyclase activity
MUA28_RS10875	COG2195	Cleaves the N-terminal amino acid of tripeptides
MUA28_RS10880	COG1929	Belongs to the glycerate kinase type-1 family
MUA28_RS10900	COG0812	UDP-N-acetylmuramate dehydrogenase activity
MUA28_RS10910	COG4607	ABC-type enterochelin transport system periplasmic component
MUA28_RS10915	COG4604	ABC transporter, ATP-binding protein
MUA28_RS10920	COG4605	iron ion homeostasis
MUA28_RS10925	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MUA28_RS10930	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MUA28_RS10935	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MUA28_RS10940	COG1780	Probably involved in ribonucleotide reductase function
MUA28_RS10950	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
MUA28_RS10955	COG3104	oligopeptide transport
MUA28_RS10960	COG3104	oligopeptide transport
MUA28_RS10965	COG2226	methyltransferase
MUA28_RS10980	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
MUA28_RS10990	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
MUA28_RS10995	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
MUA28_RS11000	COG1174	glycine betaine transport
MUA28_RS11010	COG0514	ATP-dependent DNA helicase (RecQ)
MUA28_RS11015	COG0488	(ABC) transporter
MUA28_RS11020	COG1368	sulfuric ester hydrolase activity
MUA28_RS11030	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
MUA28_RS11055	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
MUA28_RS11060	COG0720	synthase
MUA28_RS11080	COG0656	L-ascorbic acid biosynthetic process
MUA28_RS11090	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
MUA28_RS11115	COG1253	flavin adenine dinucleotide binding
MUA28_RS11120	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
MUA28_RS11120	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
MUA28_RS11120	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
MUA28_RS11125	COG1105	Belongs to the carbohydrate kinase PfkB family
MUA28_RS11130	COG1349	DNA-binding transcription factor activity
MUA28_RS11135	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
MUA28_RS11145	COG0039	L-malate dehydrogenase activity
MUA28_RS11150	COG1464	Belongs to the NlpA lipoprotein family
MUA28_RS11170	COG0471	metal ion transport
MUA28_RS11180	COG0039	L-malate dehydrogenase activity
MUA28_RS11190	COG4989	oxidoreductase activity
MUA28_RS11195	COG0523	cobalamin synthesis protein
MUA28_RS11205	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
MUA28_RS11210	COG4988	ABC transporter
MUA28_RS11215	COG1968	undecaprenyl-diphosphatase activity
MUA28_RS11225	COG1671	Belongs to the UPF0178 family
MUA28_RS11265	COG0583	DNA-binding transcription factor activity
MUA28_RS11345	COG0217	transcriptional regulatory protein
MUA28_RS11355	COG2207	Transcriptional regulator
MUA28_RS11365	COG3942	CHAP domain
MUA28_RS11365	COG1388	LysM domain
MUA28_RS11370	COG0306	phosphate transporter
MUA28_RS11375	COG1392	Phosphate transport regulator
MUA28_RS11380	COG0577	efflux transmembrane transporter activity
MUA28_RS11385	COG1136	(ABC) transporter
MUA28_RS11390	COG2205	protein histidine kinase activity
MUA28_RS11410	COG3949	Membrane
MUA28_RS11420	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MUA28_RS11425	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MUA28_RS11430	COG1120	ATPase activity
MUA28_RS11435	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
MUA28_RS11440	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
MUA28_RS11445	COG1132	(ABC) transporter
MUA28_RS11450	COG1686	Belongs to the peptidase S11 family
MUA28_RS11455	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
MUA28_RS11460	COG1216	Glycosyl transferase, family 2
MUA28_RS11465	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
MUA28_RS11470	COG1682	transport, permease protein
MUA28_RS11475	COG1134	teichoic acid transport
MUA28_RS11480	COG5609	conserved protein (DUF2294)
MUA28_RS11485	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
MUA28_RS11500	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
MUA28_RS11515	COG1247	-acetyltransferase
MUA28_RS11520	COG0671	phosphoesterase, PA-phosphatase related
MUA28_RS11530	COG1121	(ABC) transporter
MUA28_RS11535	COG1108	ABC-type Mn2 Zn2 transport systems permease components
MUA28_RS11540	COG0803	Belongs to the bacterial solute-binding protein 9 family
MUA28_RS11550	COG2348	transferase activity, transferring amino-acyl groups
MUA28_RS11555	COG0025	NhaP-type Na H and K H
MUA28_RS11600	COG0546	phosphoglycolate phosphatase activity
MUA28_RS11605	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MUA28_RS11610	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
MUA28_RS11615	COG0018	arginyl-trna synthetase
MUA28_RS11625	COG1473	amidohydrolase
MUA28_RS11635	COG1078	dGTPase activity
MUA28_RS11640	COG0519	Catalyzes the synthesis of GMP from XMP
MUA28_RS11650	COG4844	belongs to the
MUA28_RS11670	COG0095	Lipoate-protein ligase
MUA28_RS11675	COG0280	phosphate acetyltransferase
MUA28_RS11680	COG3253	May function as heme-dependent peroxidase
MUA28_RS11700	COG1132	(ABC) transporter
MUA28_RS11710	COG1129	ABC transporter
MUA28_RS11725	COG0586	Pfam SNARE associated Golgi protein
MUA28_RS11730	COG0531	amino acid
MUA28_RS11735	COG2363	Small membrane protein
MUA28_RS11745	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
MUA28_RS11755	COG0737	Belongs to the 5'-nucleotidase family
MUA28_RS11770	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
MUA28_RS11775	COG3639	organic phosphonate transmembrane transporter activity
MUA28_RS11785	COG1469	GTP cyclohydrolase I activity
MUA28_RS11790	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
MUA28_RS11795	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
MUA28_RS11800	COG0363	glucosamine-6-phosphate deaminase activity
MUA28_RS11805	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
MUA28_RS11815	COG0431	NADPH-dependent FMN reductase
MUA28_RS11820	COG0561	phosphatase activity
MUA28_RS11830	COG1428	Deoxynucleoside kinase
MUA28_RS11835	COG1428	Deoxynucleoside kinase
MUA28_RS11840	COG0561	phosphatase activity
MUA28_RS11850	COG0546	phosphoglycolate phosphatase activity
MUA28_RS11855	COG2832	Protein of unknown function (DUF454)
MUA28_RS11865	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
MUA28_RS11870	COG1619	proteins homologs of microcin C7 resistance protein MccF
MUA28_RS11885	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
MUA28_RS11890	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
MUA28_RS11910	COG1473	amidohydrolase
MUA28_RS11915	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
MUA28_RS11920	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
MUA28_RS11925	COG0049	tRNA binding
MUA28_RS11930	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
MUA28_RS11940	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MUA28_RS11945	COG0085	RNA polymerase activity
MUA28_RS11950	COG2813	Specifically methylates the guanine in position
MUA28_RS11955	COG0222	ribosome binding
MUA28_RS11960	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
MUA28_RS11965	COG0081	regulation of translation
MUA28_RS11970	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
MUA28_RS11975	COG0250	Participates in transcription elongation, termination and antitermination
MUA28_RS11985	COG0267	Belongs to the bacterial ribosomal protein bL33 family
MUA28_RS12000	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MUA28_RS12005	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
MUA28_RS12010	COG0215	cysteine-tRNA ligase activity
MUA28_RS12015	COG1045	serine acetyltransferase
MUA28_RS12025	COG4956	integral membrane protein (PIN domain superfamily)
MUA28_RS12030	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
MUA28_RS12035	COG0542	response to heat
MUA28_RS12040	COG3869	Catalyzes the specific phosphorylation of arginine residues in
MUA28_RS12055	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
MUA28_RS12070	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
MUA28_RS12075	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
MUA28_RS12080	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MUA28_RS12090	COG2814	Major facilitator Superfamily
MUA28_RS12175	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
MUA28_RS12180	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MUA28_RS12185	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
MUA28_RS12205	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
MUA28_RS12210	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MUA28_RS12225	COG1098	S1 RNA binding domain
MUA28_RS12235	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
MUA28_RS12240	COG3956	TIGRFAM MazG family protein
MUA28_RS12245	COG2244	polysaccharide biosynthetic process
MUA28_RS12250	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
MUA28_RS12255	COG0193	aminoacyl-tRNA hydrolase activity
MUA28_RS12260	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
MUA28_RS12265	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MUA28_RS12270	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
MUA28_RS12275	COG2088	sporulation resulting in formation of a cellular spore
MUA28_RS12280	COG0251	oxidation-reduction process
MUA28_RS12285	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
MUA28_RS12295	COG4466	Protein conserved in bacteria
MUA28_RS12300	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
MUA28_RS12305	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
MUA28_RS12310	COG0084	hydrolase, TatD family'
MUA28_RS12315	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MUA28_RS12315	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MUA28_RS12370	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
MUA28_RS12375	COG2827	Endonuclease containing a URI domain
MUA28_RS12380	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
MUA28_RS12390	COG1774	PSP1 C-terminal conserved region
MUA28_RS12395	COG0470	DNA polymerase III
MUA28_RS12400	COG3870	Protein conserved in bacteria
MUA28_RS12405	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
MUA28_RS12410	COG1982	Orn Lys Arg decarboxylase major
MUA28_RS12430	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
MUA28_RS12440	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MUA28_RS12470	COG2814	Major facilitator Superfamily
MUA28_RS12475	COG0583	DNA-binding transcription factor activity
MUA28_RS12485	COG2188	Transcriptional regulator
MUA28_RS12490	COG0366	Alpha amylase catalytic
MUA28_RS12495	COG1263	PTS System
MUA28_RS12495	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MUA28_RS12500	COG0346	lactoylglutathione lyase activity
MUA28_RS12510	COG0493	'glutamate synthase
MUA28_RS12515	COG0070	glutamate synthase
MUA28_RS12515	COG0067	glutamate synthase
MUA28_RS12515	COG0069	glutamate synthase activity
MUA28_RS12520	COG0583	DNA-binding transcription factor activity
MUA28_RS12545	COG4841	protein insertion into membrane
MUA28_RS12555	COG0737	Belongs to the 5'-nucleotidase family
MUA28_RS12560	COG2162	N-hydroxyarylamine O-acetyltransferase activity
MUA28_RS12570	COG0626	cystathionine gamma-synthase activity
MUA28_RS12575	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
MUA28_RS12580	COG1266	CAAX protease self-immunity
MUA28_RS12585	COG0733	neurotransmitter:sodium symporter activity
MUA28_RS12595	COG1647	Serine aminopeptidase, S33
MUA28_RS12600	COG1755	Isoprenylcysteine carboxyl methyltransferase
MUA28_RS12605	COG1279	arginine transmembrane transporter activity
MUA28_RS12615	COG0346	lactoylglutathione lyase activity
MUA28_RS12635	COG1695	Transcriptional regulator
MUA28_RS12640	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
MUA28_RS12645	COG1683	Conserved Protein
MUA28_RS12670	COG0529	Catalyzes the synthesis of activated sulfate
MUA28_RS12675	COG2046	Belongs to the sulfate adenylyltransferase family
MUA28_RS12680	COG0730	response to heat
MUA28_RS12690	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
MUA28_RS12695	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
MUA28_RS12700	COG0175	sulfate reduction
MUA28_RS12705	COG1216	Glycosyl transferase, family 2
MUA28_RS12715	COG1051	belongs to the nudix hydrolase family
MUA28_RS12730	COG2514	catechol 2,3-dioxygenase activity
MUA28_RS12735	COG0519	Catalyzes the synthesis of GMP from XMP
MUA28_RS12735	COG0518	GMP synthase (glutamine-hydrolyzing) activity
MUA28_RS12745	COG2233	PERMEase
MUA28_RS12750	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
MUA28_RS12770	COG1823	symporter activity
MUA28_RS12775	COG0778	Nitroreductase
MUA28_RS12785	COG0450	alkyl hydroperoxide reductase
MUA28_RS12790	COG3634	alkyl hydroperoxide reductase activity
MUA28_RS12815	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
MUA28_RS12840	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
MUA28_RS12850	COG0360	Binds together with S18 to 16S ribosomal RNA
MUA28_RS12870	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
MUA28_RS12900	COG0012	GTP binding
MUA28_RS12905	COG4481	Protein conserved in bacteria
MUA28_RS12910	COG0668	transmembrane transport
MUA28_RS12915	COG1475	DNA binding
MUA28_RS12920	COG0626	cystathionine gamma-synthase activity
MUA28_RS12925	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
MUA28_RS12925	COG0646	methionine synthase
MUA28_RS12930	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
MUA28_RS12940	COG0436	Aminotransferase
MUA28_RS12955	COG1475	DNA binding
MUA28_RS12960	COG0357	Ribosomal RNA small subunit methyltransferase G
MUA28_RS12970	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
MUA28_RS12975	COG0594	ribonuclease P activity
MUA28_RS12995	COG1192	Involved in chromosome partitioning
MUA28_RS13040	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MUA28_RS13090	COG0589	response to stress
MUA28_RS13095	COG0659	secondary active sulfate transmembrane transporter activity
MUA28_RS13120	COG0786	glutamate:sodium symporter activity
MUA28_RS13125	COG1278	Cold shock
MUA28_RS13220	COG2807	transmembrane transport
MUA28_RS13255	COG3237	CsbD-like