locus-tag	class	description
FGL66_RS00005	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
FGL66_RS00010	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
FGL66_RS00015	ENOG4107ZQN	disulfide bond
FGL66_RS00025	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
FGL66_RS00030	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
FGL66_RS00035	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
FGL66_RS00040	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
FGL66_RS00055	ENOG4108UMN	azlc family
FGL66_RS00065	ENOG4105DWV	Homoserine O-trans-acetylase
FGL66_RS00070	ENOG4108XMW	Membrane
FGL66_RS00075	ENOG4105BZR	domain protein
FGL66_RS00080	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
FGL66_RS00085	ENOG4105CDU	Replicative dna helicase
FGL66_RS00090	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
FGL66_RS00095	ENOG4108JYZ	YitT family
FGL66_RS00115	ENOG4105BZU	Histidine kinase
FGL66_RS00130	ENOG4105Q2H	domain protein
FGL66_RS00180	ENOG4107Y9U	Membrane
FGL66_RS00205	ENOG4105DZR	Type I site-specific deoxyribonuclease
FGL66_RS00225	ENOG4108VXD	carboxy-peptidase
FGL66_RS00245	ENOG4105CJH	Alcohol dehydrogenase zinc-binding domain protein
FGL66_RS00250	ENOG4105DBV	ornithine carbamoyltransferase
FGL66_RS00255	ENOG4107QNK	)-transporter
FGL66_RS00275	ENOG4105CV8	reductase
FGL66_RS00295	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
FGL66_RS00340	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
FGL66_RS00345	ENOG4108J8C	transporter major facilitator family protein
FGL66_RS00350	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
FGL66_RS00360	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
FGL66_RS00375	ENOG4105DWT	malate dehydrogenase (quinone)
FGL66_RS00380	ENOG4105DAA	L-lactate
FGL66_RS00385	ENOG4105C5Y	PTS System
FGL66_RS00390	ENOG4105CG3	alpha amylase, catalytic region
FGL66_RS00395	ENOG4107414	GntR family transcriptional regulator
FGL66_RS00410	ENOG4105C6E	dna polymerase iii
FGL66_RS00415	ENOG410816I	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
FGL66_RS00420	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
FGL66_RS00440	ENOG4105CXN	decarboxylase
FGL66_RS00445	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
FGL66_RS00450	ENOG4105X0R	protein from nitrogen regulatory protein P-II
FGL66_RS00455	ENOG4105FA2	dna polymerase iii
FGL66_RS00460	ENOG4105MA4	psp1 domain protein
FGL66_RS00465	ENOG4105QD5	Involved in initiation control of chromosome replication (By similarity)
FGL66_RS00470	ENOG41060K3	Methyltransferase
FGL66_RS00475	ENOG4105VC4	domain protein
FGL66_RS00480	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
FGL66_RS00485	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
FGL66_RS00490	ENOG4105F8V	Hydrolase, tatD family
FGL66_RS00495	ENOG4105HVR	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step (By similarity)
FGL66_RS00500	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
FGL66_RS00505	ENOG4105W42	Veg protein
FGL66_RS00510	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
FGL66_RS00515	ENOG4105DFT	pur operon repressor
FGL66_RS00520	ENOG4105KME	endoribonuclease L-psp
FGL66_RS00525	ENOG4105K4W	Could be involved in septation (By similarity)
FGL66_RS00530	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
FGL66_RS00535	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
FGL66_RS00540	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
FGL66_RS00545	ENOG4108ZUB	Lysine exporter protein (Lyse ygga)
FGL66_RS00550	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
FGL66_RS00555	ENOG4108JA2	transcriptioN-repair coupling factor
FGL66_RS00565	ENOG4108IY2	MazG family
FGL66_RS00570	ENOG41082I2	s4 domain protein
FGL66_RS00580	ENOG41060GV	RNA binding s1 domain protein
FGL66_RS00585	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
FGL66_RS00590	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
FGL66_RS00595	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
FGL66_RS00600	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
FGL66_RS00605	ENOG4105C6T	cysteine synthase
FGL66_RS00615	ENOG4105KRF	dihydroneopterin aldolase
FGL66_RS00620	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FGL66_RS00625	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
FGL66_RS00715	ENOG4105ME7	Membrane
FGL66_RS00720	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
FGL66_RS00725	ENOG4105CD9	Involved in the production of pyridoxal phosphate, probably by incorporating ammonia into the pyridine ring (By similarity)
FGL66_RS00730	ENOG4108UHX	Involved in the hydrolysis of glutamine to glutamate and ammonia. Channels an ammonia molecule to PdxS (By similarity)
FGL66_RS00735	ENOG4105D9N	nucleoside
FGL66_RS00745	ENOG4108Z0C	Uvrb UvrC protein
FGL66_RS00750	ENOG41066A3	ATP guanido phosphotransferase
FGL66_RS00755	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
FGL66_RS00760	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
FGL66_RS00765	ENOG4105CTP	PilT protein domain protein
FGL66_RS00770	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
FGL66_RS00780	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
FGL66_RS00785	ENOG4105D7W	serine acetyltransferase
FGL66_RS00790	ENOG4105C8N	cysteinyl-tRNA synthetase
FGL66_RS00795	ENOG4105KEB	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
FGL66_RS00820	ENOG410683Z	Preprotein translocase SecE subunit
FGL66_RS00825	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
FGL66_RS00830	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
FGL66_RS00835	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
FGL66_RS00840	ENOG4108VZM	50s ribosomal protein L10
FGL66_RS00850	ENOG4107Y49	methyltransferase
FGL66_RS00855	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
FGL66_RS00860	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
FGL66_RS00870	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
FGL66_RS00875	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
FGL66_RS00880	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
FGL66_RS00885	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
FGL66_RS00900	ENOG4105EXW	epimerase dehydratase
FGL66_RS00905	ENOG4105CM2	brancheD-chain amino acid aminotransferase
FGL66_RS00915	ENOG4105ZMH	deoxynucleoside kinase
FGL66_RS00920	ENOG4105ZMH	deoxynucleoside kinase
FGL66_RS00925	ENOG4108Z6B	deaminase
FGL66_RS00930	ENOG410667J	hydrolase
FGL66_RS00935	ENOG4107YFT	Nadph-dependent fmn reductase
FGL66_RS00940	ENOG4105DZA	Converts GTP to 7,8-dihydroneopterin triphosphate (By similarity)
FGL66_RS00945	ENOG4107YEI	lmbE family
FGL66_RS00960	ENOG4105CI1	PTS System
FGL66_RS00965	ENOG4105C9S	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P) (By similarity)
FGL66_RS00970	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
FGL66_RS00975	ENOG4108VA3	3-hexulose-6-phosphate synthase
FGL66_RS00980	ENOG41080HJ	6-phospho 3-hexuloisomerase
FGL66_RS00995	ENOG4105G9B	Transcriptional regulator
FGL66_RS01000	ENOG4105EW8	cytosine purines, uracil, thiamine, allantoin permease
FGL66_RS01005	ENOG4107RNN	dihydropyrimidinase (EC 3.5.2.2)
FGL66_RS01010	ENOG4105CE7	Amidase, hydantoinase carbamoylase family
FGL66_RS01020	ENOG4105CE7	Amidase, hydantoinase carbamoylase family
FGL66_RS01025	ENOG4105S0E	allantoin catabolism protein
FGL66_RS01030	ENOG4105DG4	malate L-lactate dehydrogenase
FGL66_RS01035	ENOG4105DG4	malate L-lactate dehydrogenase
FGL66_RS01040	ENOG4107R1Q	Membrane protein FdrA
FGL66_RS01045	ENOG4107REC	cytoplasmic protein
FGL66_RS01055	ENOG4105C5B	carbamate kinase
FGL66_RS01060	ENOG4105EKQ	RNA-directed DNA polymerase
FGL66_RS01075	ENOG4105DWF	phosphomethylpyrimidine kinase
FGL66_RS01080	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
FGL66_RS01090	ENOG4105M08	Membrane
FGL66_RS01095	ENOG4105CUB	amino acid
FGL66_RS01100	ENOG4105JGI	Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes (By similarity)
FGL66_RS01105	ENOG4108IJ2	phosphate acetyltransferase
FGL66_RS01115	ENOG4107R7I	amino acid
FGL66_RS01130	ENOG4105C8P	)-transporter
FGL66_RS01135	ENOG4105QAT	UPF0741 protein
FGL66_RS01150	ENOG4105DCI	Phosphohydrolase
FGL66_RS01155	ENOG4108XFG	YwhD family
FGL66_RS01170	ENOG4105JKQ	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity)
FGL66_RS01175	ENOG4105EHG	Permease protein
FGL66_RS01180	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
FGL66_RS01230	ENOG4105C8S	subunit m
FGL66_RS01235	ENOG4108PMQ	Na H antiporter MnhB subunit-related protein
FGL66_RS01240	ENOG4105MKQ	Monovalent cation H antiporter subunit C
FGL66_RS01250	ENOG4105IMY	monovalent cation H antiporter subunit E
FGL66_RS01255	ENOG410684G	monovalent cation H antiporter subunit F
FGL66_RS01260	ENOG4105KJM	monovalent cation h antiporter subunit g
FGL66_RS01265	ENOG4105DSE	periplasmic solute binding protein
FGL66_RS01270	ENOG4105CC5	ABC transporter
FGL66_RS01275	ENOG4105DIK	(ABC) transporter
FGL66_RS01290	ENOG4108UHC	Glycosyl transferase, wecb taga cpsf family
FGL66_RS01295	ENOG4105EY8	ABC transporter
FGL66_RS01310	ENOG4107YSK	Glycerol-3-phosphate cytidylyltransferase
FGL66_RS01315	ENOG4107SJB	teichoic acid biosynthesis
FGL66_RS01325	ENOG4105BZ1	(ABC) transporter
FGL66_RS01345	ENOG410749K	Uncharacterized protein conserved in bacteria (DUF2179)
FGL66_RS01350	ENOG4105E0A	ABC, transporter
FGL66_RS01355	ENOG4105DQ5	transport system permease protein
FGL66_RS01360	ENOG4105EHG	Permease protein
FGL66_RS01370	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
FGL66_RS01375	ENOG4108K88	Membrane
FGL66_RS01385	ENOG4105CJZ	response regulator
FGL66_RS01395	ENOG4105C19	ABC transporter
FGL66_RS01400	ENOG4108HVR	ABC transporter, permease
FGL66_RS01405	ENOG4107GRR	phosphate transport regulator
FGL66_RS01410	ENOG4105CJ3	phosphate transporter
FGL66_RS01415	ENOG4105VRS	hydrolase family 18
FGL66_RS01425	ENOG4108F19	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
FGL66_RS01430	ENOG4105CDY	transcriptional regulatory protein
FGL66_RS01455	ENOG4105S8Q	sugar efflux transporter
FGL66_RS01460	ENOG4105SXS	Protein of unknown function (DUF456)
FGL66_RS01485	ENOG4108URH	decarboxylase
FGL66_RS01490	ENOG4107XJU	UPF0178 protein
FGL66_RS01500	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
FGL66_RS01505	ENOG4105K56	Transcriptional regulator
FGL66_RS01510	ENOG4105CKI	cobalamin synthesis protein
FGL66_RS01515	ENOG4107QM2	Aldo Keto reductase
FGL66_RS01525	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
FGL66_RS01535	ENOG4105DP8	Major facilitator superfamily MFS_1
FGL66_RS01540	ENOG4107SJB	teichoic acid biosynthesis
FGL66_RS01545	ENOG4108Z66	YbaK ebsC protein
FGL66_RS01550	ENOG4105E98	transcriptional regulator DeoR family
FGL66_RS01555	ENOG4105DE4	1-phosphofructokinase
FGL66_RS01560	ENOG4105DM4	PTS System
FGL66_RS01565	ENOG4105C37	(CBS) domain
FGL66_RS01580	ENOG4105CKK	Glycosyl transferase, family 2
FGL66_RS01610	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
FGL66_RS01615	ENOG4107ZAE	6-carboxy-5,6,7,8-tetrahydropterin synthase
FGL66_RS01625	ENOG4105DDQ	anthranilate synthase
FGL66_RS01655	ENOG4105E0M	Sulfatase
FGL66_RS01665	ENOG4105C5H	ABC transporter
FGL66_RS01670	ENOG4105C9U	ATP-dependent DNA helicase RecQ
FGL66_RS01675	ENOG4108IJ8	ABC transporter
FGL66_RS01680	ENOG4105E90	ABC transporter
FGL66_RS01685	ENOG4105CIH	Imidazole acetol-phosphate transaminase
FGL66_RS01690	ENOG4108ZIE	5 nucleotidase deoxy cytosolic type C
FGL66_RS01695	ENOG4105DUX	Transporter
FGL66_RS01700	ENOG4105DUX	Transporter
FGL66_RS01705	ENOG4105CSD	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
FGL66_RS01720	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
FGL66_RS01725	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
FGL66_RS01755	ENOG4105BZW	Glycerate kinase
FGL66_RS01760	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
FGL66_RS01780	ENOG4105ESV	Glycosyl transferase, family 4
FGL66_RS01785	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
FGL66_RS01790	ENOG4105EPR	degv family
FGL66_RS01805	ENOG4105MS2	ribosomal subunit Interface protein
FGL66_RS01810	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
FGL66_RS01820	ENOG41068JE	domain protein
FGL66_RS01840	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
FGL66_RS01850	ENOG4105D1C	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion (By similarity)
FGL66_RS01870	ENOG4105C3M	thioredoxin reductase
FGL66_RS01875	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
FGL66_RS01880	ENOG4105CHW	UPF0052 protein
FGL66_RS01885	ENOG4105CIE	May be required for sporulation (By similarity)
FGL66_RS01890	ENOG4105KA3	membrAne
FGL66_RS01895	ENOG4105VEQ	Cold shock protein
FGL66_RS01910	ENOG4108Z7F	N-acetyltransferase
FGL66_RS01915	ENOG4105ECP	epimerase
FGL66_RS01930	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
FGL66_RS01935	ENOG4105BZA	Phosphoglycerate kinase
FGL66_RS01940	ENOG4105CP7	Triose-phosphate isomerase
FGL66_RS01945	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
FGL66_RS01965	ENOG4105XZU	Preprotein translocase, subunit SecG
FGL66_RS01975	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
FGL66_RS02000	ENOG4106432	Mediates binding to human platelets, possibly through a receptor-ligand interaction. Probably associated with virulence in endovascular infection (By similarity)
FGL66_RS02005	ENOG4108ZHJ	Organic hydroperoxide resistance protein
FGL66_RS02015	ENOG4105FF2	Type I DHQase
FGL66_RS02025	ENOG4105SZ6	Thioredoxin
FGL66_RS02030	ENOG41080E8	Transcriptional regulator, Spx MgsR family
FGL66_RS02045	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
FGL66_RS02050	ENOG4108UMI	ABC transporter, permease
FGL66_RS02055	ENOG4105D01	(LipO)protein
FGL66_RS02060	ENOG4105D01	(LipO)protein
FGL66_RS02085	ENOG4105C3K	feS assembly ATPase SufC
FGL66_RS02090	ENOG4105JRK	feS assembly protein SufD
FGL66_RS02095	ENOG4105C9B	Cysteine desulfurase
FGL66_RS02100	ENOG4108UNV	SUF system FeS assembly protein, NifU family
FGL66_RS02105	ENOG4105DIW	FeS assembly protein SUFB
FGL66_RS02120	ENOG4108JU6	CBS domain protein
FGL66_RS02125	ENOG4105I3N	Conserved Protein
FGL66_RS02135	ENOG4107R8B	5'-nucleotidase
FGL66_RS02140	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
FGL66_RS02145	ENOG4105MMD	transcriptional regulator
FGL66_RS02160	ENOG4105D4U	had-superfamily hydrolase, subfamily iia
FGL66_RS02165	ENOG4105C5I	Dehydrogenase
FGL66_RS02175	ENOG41083MR	nifu domain-containing protein
FGL66_RS02185	ENOG4105ZKE	UPF0349 protein
FGL66_RS02190	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
FGL66_RS02195	ENOG4105CEP	NADH dehydrogenase
FGL66_RS02200	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
FGL66_RS02205	ENOG4105D3Y	Na H antiporter
FGL66_RS02210	ENOG4105KA0	thioesterase Superfamily protein
FGL66_RS02230	ENOG4105W4C	monovalent cation H antiporter subunit F
FGL66_RS02240	ENOG4108JPZ	Monovalent cation H antiporter subunit D
FGL66_RS02245	ENOG4105MKQ	Monovalent cation H antiporter subunit C
FGL66_RS02255	ENOG4105D65	subunit l
FGL66_RS02265	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
FGL66_RS02280	ENOG4105C26	Dehydrogenase
FGL66_RS02285	ENOG4105C8Y	Acetylornithine aminotransferase
FGL66_RS02290	ENOG4105D82	Glutamate dehydrogenase
FGL66_RS02295	ENOG4105CH7	arginosuccinase
FGL66_RS02300	ENOG4105CDH	Citrulline--aspartate ligase
FGL66_RS02315	ENOG4105C5N	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
FGL66_RS02320	ENOG4107R2I	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation
FGL66_RS02325	ENOG4105ERH	Fumarylacetoacetate hydrolase
FGL66_RS02335	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
FGL66_RS02340	ENOG4108KP7	hydrolase
FGL66_RS02345	ENOG4105VG1	fes assembly suf system protein
FGL66_RS02355	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
FGL66_RS02370	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
FGL66_RS02380	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
FGL66_RS02385	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
FGL66_RS02395	ENOG4108JQ7	(ABC) transporter
FGL66_RS02405	ENOG4105C31	Tryptophanyl-tRNA synthetase
FGL66_RS02410	ENOG41090SU	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress (By similarity)
FGL66_RS02415	ENOG4108SQ7	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
FGL66_RS02425	ENOG4105DPN	Oligoendopeptidase f
FGL66_RS02430	ENOG4105T58	Dithiol-disulfide isomerase
FGL66_RS02435	ENOG4108Z18	K06886 hemoglobin
FGL66_RS02440	ENOG4105MIX	Adenylate cyclase
FGL66_RS02445	ENOG4106EFP	UPF0738 protein
FGL66_RS02455	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
FGL66_RS02460	ENOG4105EMS	pseudouridine synthase
FGL66_RS02465	ENOG4105CJW	magnesium transporter
FGL66_RS02475	ENOG4108M1Z	surface protein
FGL66_RS02485	ENOG4105C02	permease
FGL66_RS02490	ENOG4105BZG	amino acid carrier protein
FGL66_RS02505	ENOG4108PK2	permease that is required for glycolipid anchoring of LTA. May facilitate the transport of diglucosyl- diacylglycerol (Glc2-DAG) from the inner to the outer leaflet of the cytoplasmic membrane, delivering Glc2-DAG as a substrate for LTA synthesis, thereby generating glycolipid-anchored LTA. Appears to play an important role in virulence
FGL66_RS02510	ENOG4108QBV	Monogalactosyldiacylglycerol synthase
FGL66_RS02515	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
FGL66_RS02525	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
FGL66_RS02530	ENOG4107TS3	membrane protein, TerC
FGL66_RS02570	ENOG4107RNS	bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase 3'-nucleotidase periplasmic
FGL66_RS02640	ENOG41083J0	(ABC) transporter
FGL66_RS02645	ENOG4105C4B	ABC transporter, permease
FGL66_RS02650	ENOG4105EIS	1,4-dihydroxy-2-naphthoate octaprenyltransferase
FGL66_RS02655	ENOG4105E4F	Isochorismate synthase
FGL66_RS02660	ENOG4105C4A	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity)
FGL66_RS02670	ENOG4108IPT	Naphthoate synthase
FGL66_RS02675	ENOG4105CHM	Aminotransferase
FGL66_RS02680	ENOG4108TGC	Acyltransferase
FGL66_RS02700	ENOG4108HPG	-acetyltransferase
FGL66_RS02710	ENOG4108KGH	TRANSCRIPTIONal
FGL66_RS02715	ENOG4107QSU	Phosphoglucomutase phosphomannomutase alpha beta alpha domain
FGL66_RS02725	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
FGL66_RS02735	ENOG4105E2S	oxidase) subunit II
FGL66_RS02750	ENOG41060D1	Quinol oxidase
FGL66_RS02755	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
FGL66_RS02760	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
FGL66_RS02765	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
FGL66_RS02770	ENOG4105C8V	SAICAR synthetase
FGL66_RS02775	ENOG4105VR9	phosphoribosylformylglycinamidine synthase
FGL66_RS02780	ENOG4105D21	Phosphoribosylformylglycinamidine synthase I
FGL66_RS02785	ENOG4108JIU	phosphoribosylformylglycinamidine synthase ii
FGL66_RS02795	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
FGL66_RS02805	ENOG4105DC1	bifunctional purine biosynthesis protein purh
FGL66_RS02810	ENOG4105C12	Phosphoribosylglycinamide synthetase
FGL66_RS02820	ENOG4108JJB	ABC transporter
FGL66_RS02835	ENOG4105DR4	Methyltransferase
FGL66_RS02865	ENOG4107ZYR	domain protein
FGL66_RS02870	ENOG4105CN5	Metallo-Beta-Lactamase
FGL66_RS02875	ENOG4106148	UPF0356 protein
FGL66_RS02880	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
FGL66_RS02895	ENOG4105CPP	Dehydrogenase, E1 component
FGL66_RS02900	ENOG4105C7S	Dehydrogenase
FGL66_RS02905	ENOG4107QN2	dihydrolipoyl dehydrogenase
FGL66_RS02910	ENOG4105WBI	UPF0223 protein
FGL66_RS02920	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
FGL66_RS02925	ENOG4105D81	ABC transporter, permease
FGL66_RS02930	ENOG4105D38	putrescine abc transporter
FGL66_RS02935	ENOG4107RUE	extracellular solute-binding protein family 1
FGL66_RS02950	ENOG4108WQ8	UPF0637 protein
FGL66_RS02955	ENOG4105ECY	inositol monophosphatase
FGL66_RS02965	ENOG4105CI3	gtp-binding protein typa
FGL66_RS02970	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
FGL66_RS02985	ENOG4105ZPI	UPF0358 protein
FGL66_RS02990	ENOG4105CNI	cell division protein FtsW
FGL66_RS03000	ENOG4107SGF	Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group (By similarity)
FGL66_RS03005	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
FGL66_RS03030	ENOG4105TRI	Hydrolase
FGL66_RS03085	ENOG4105WUC	UPF0298 protein
FGL66_RS03095	ENOG4106H78	methyltransferase
FGL66_RS03100	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
FGL66_RS03115	ENOG41067VY	50S ribosomal protein L32
FGL66_RS03120	ENOG4108RWN	rrna methyltransferase
FGL66_RS03125	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
FGL66_RS03130	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
FGL66_RS03135	ENOG4107FSS	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
FGL66_RS03150	ENOG4105DCG	PHP domain protein
FGL66_RS03160	ENOG4105K63	Thioredoxin
FGL66_RS03165	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
FGL66_RS03170	ENOG4108NU2	Succinate dehydrogenase cytochrome b558 subunit
FGL66_RS03180	ENOG4105E33	succinate dehydrogenase
FGL66_RS03210	ENOG4108SC4	)-transporter
FGL66_RS03265	ENOG4108YG3	N-acetyltransferase
FGL66_RS03270	ENOG41074B2	UPF0747 protein
FGL66_RS03275	ENOG4108V6E	Cell division protein mraZ
FGL66_RS03280	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
FGL66_RS03285	ENOG41068DC	Essential cell division protein (By similarity)
FGL66_RS03290	ENOG4105CJN	penicillin-binding protein
FGL66_RS03300	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
FGL66_RS03310	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
FGL66_RS03315	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
FGL66_RS03320	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
FGL66_RS03325	ENOG4105DFA	alanine racemase domain protein
FGL66_RS03330	ENOG4105VR5	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA (By similarity)
FGL66_RS03335	ENOG41067XK	integral membrane protein
FGL66_RS03350	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
FGL66_RS03355	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
FGL66_RS03360	ENOG4105C34	Pseudouridine synthase
FGL66_RS03365	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
FGL66_RS03380	ENOG4105CD3	dihydroorotase
FGL66_RS03385	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
FGL66_RS03390	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
FGL66_RS03400	ENOG4107RY0	Catalyzes the conversion of dihydroorotate to orotate (By similarity)
FGL66_RS03405	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
FGL66_RS03410	ENOG41065E1	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
FGL66_RS03430	ENOG41067UH	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
FGL66_RS03435	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
FGL66_RS03440	ENOG4105C25	Primosomal protein n'
FGL66_RS03500	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
FGL66_RS03505	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
FGL66_RS03510	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
FGL66_RS03515	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
FGL66_RS03520	ENOG4108ZF3	Phosphatase
FGL66_RS03530	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
FGL66_RS03535	ENOG4105DJV	ribulose-phosphate 3-epimerase
FGL66_RS03550	ENOG4108ZAA	Alkaline-shock protein
FGL66_RS03565	ENOG4105EJQ	L-serine dehydratase
FGL66_RS03570	ENOG4105CB5	ATP-dependent DNA helicase recG
FGL66_RS03580	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
FGL66_RS03590	ENOG4105CHR	reductase
FGL66_RS03595	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
FGL66_RS03600	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
FGL66_RS03605	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
FGL66_RS03610	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
FGL66_RS03615	ENOG4105VBN	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein (By similarity)
FGL66_RS03625	ENOG4105K5M	30s ribosomal protein S16
FGL66_RS03635	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
FGL66_RS03660	ENOG4105C9W	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity)
FGL66_RS03665	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
FGL66_RS03675	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
FGL66_RS03680	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
FGL66_RS03685	ENOG4105C79	DNA protecting protein DprA
FGL66_RS03690	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
FGL66_RS03695	ENOG4107QXI	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs (By similarity)
FGL66_RS03700	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
FGL66_RS03710	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
FGL66_RS03720	ENOG4105CE9	30S ribosomal protein S2
FGL66_RS03725	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
FGL66_RS03730	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
FGL66_RS03735	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
FGL66_RS03740	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
FGL66_RS03745	ENOG4105KNE	Phosphatidate cytidylyltransferase
FGL66_RS03750	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
FGL66_RS03760	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
FGL66_RS03765	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
FGL66_RS03770	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
FGL66_RS03775	ENOG4105CHV	Transcription elongation factor NusA
FGL66_RS03780	ENOG4105VZN	Nucleic-acid-binding protein implicated in transcription termination
FGL66_RS03785	ENOG4105VHM	ribosomal protein
FGL66_RS03790	ENOG4107EEM	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
FGL66_RS03795	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
FGL66_RS03800	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
FGL66_RS03805	ENOG4105DTN	riboflavin biosynthesis protein ribF
FGL66_RS03815	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
FGL66_RS03820	ENOG4105CN5	Metallo-Beta-Lactamase
FGL66_RS03830	ENOG4105FDP	GntR family transcriptional regulator
FGL66_RS03860	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
FGL66_RS03865	ENOG4105CEV	competence damage-inducible protein
FGL66_RS03870	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
FGL66_RS03875	ENOG4105E4Y	Endoribonuclease that initiates mRNA decay (By similarity)
FGL66_RS03895	ENOG4105D48	metallophosphoesterase
FGL66_RS03900	ENOG4105DI2	Pyruvate flavodoxin ferredoxin oxidoreductase domain protein
FGL66_RS03905	ENOG4105DQU	oxidoreductase, subunit beta
FGL66_RS03910	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
FGL66_RS03930	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
FGL66_RS03935	ENOG4108ZIA	glycerol-3-phosphate responsive antiterminator
FGL66_RS03940	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
FGL66_RS03945	ENOG4108HMR	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
FGL66_RS03950	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
FGL66_RS03960	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
FGL66_RS03965	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
FGL66_RS03970	ENOG4108V06	Glutathione peroxidase
FGL66_RS03975	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
FGL66_RS03980	ENOG4105CXI	aluminum resistance protein
FGL66_RS03995	ENOG4105KV4	Transcriptional regulator
FGL66_RS04055	ENOG4107YZX	Universal stress protein
FGL66_RS04065	ENOG4105DC7	peptidase M24
FGL66_RS04070	ENOG4105E8R	UPF0173 metal-dependent hydrolase
FGL66_RS04085	ENOG4105SFS	phosphoesterase RecJ domain protein
FGL66_RS04090	ENOG4105C0B	DNA polymerase III (alpha subunit)
FGL66_RS04095	ENOG4105C6K	Malic enzyme
FGL66_RS04100	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
FGL66_RS04105	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
FGL66_RS04110	ENOG4105CTQ	phosphohexokinase
FGL66_RS04115	ENOG4105CA9	Pyruvate kinase
FGL66_RS04120	ENOG4105BZN	citrate synthase
FGL66_RS04125	ENOG4108HMX	isocitrate dehydrogenase (NADP)
FGL66_RS04145	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
FGL66_RS04150	ENOG4105BZU	Histidine kinase
FGL66_RS04155	ENOG4105C2M	dna polymerase I
FGL66_RS04160	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
FGL66_RS04165	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
FGL66_RS04170	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
FGL66_RS04175	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
FGL66_RS04190	ENOG4105C22	threonyL-tRNA synthetase
FGL66_RS04195	ENOG4108IQI	permease
FGL66_RS04200	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
FGL66_RS04205	ENOG4105VJV	50s ribosomal protein L35
FGL66_RS04210	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
FGL66_RS04225	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
FGL66_RS04230	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
FGL66_RS04240	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
FGL66_RS04250	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
FGL66_RS04260	ENOG4105D52	delta-aminolevulinic acid dehydratase
FGL66_RS04265	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
FGL66_RS04275	ENOG4108R3E	Dna-3-methyladenine glycosylase i
FGL66_RS04280	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
FGL66_RS04285	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
FGL66_RS04290	ENOG4105EHH	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue (By similarity)
FGL66_RS04295	ENOG4105W5Q	DNA repair protein (RadC
FGL66_RS04305	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
FGL66_RS04315	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
FGL66_RS04320	ENOG4105X36	(ribosomal) protein
FGL66_RS04325	ENOG4105K46	50S ribosomal protein l27
FGL66_RS04340	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
FGL66_RS04360	ENOG4105VIE	preprotein translocase, subunit YajC
FGL66_RS04365	ENOG4105C3D	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
FGL66_RS04370	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
FGL66_RS04375	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
FGL66_RS04385	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
FGL66_RS04390	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
FGL66_RS04410	ENOG4105CUZ	uba thif-type nad fad binding protein
FGL66_RS04420	ENOG4105D1H	recombination factor protein RarA
FGL66_RS04435	ENOG4105EKQ	RNA-directed DNA polymerase
FGL66_RS04440	ENOG4105DEN	Luciferase family
FGL66_RS04445	ENOG4105C3J	Cysteine desulfurase
FGL66_RS04450	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
FGL66_RS04460	ENOG4105C7H	Helicase, RecD TraA family
FGL66_RS04470	ENOG4105VBH	UPF0297 protein
FGL66_RS04475	ENOG4108Z08	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
FGL66_RS04480	ENOG4105VPH	UPF0473 protein
FGL66_RS04490	ENOG4105XYU	peptidase (U32 family)
FGL66_RS04495	ENOG4105CFP	Peptidase U32
FGL66_RS04500	ENOG4105DBI	uridine monophosphokinase
FGL66_RS04510	ENOG4105P4J	Allophanate hydrolase, subunit 1
FGL66_RS04520	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
FGL66_RS04525	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
FGL66_RS04530	ENOG4105E7W	lamb ycsf family protein
FGL66_RS04535	ENOG4105C5A	transporter
FGL66_RS04540	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
FGL66_RS04545	ENOG4108WJV	had superfamily (subfamily IIIa) phosphatase
FGL66_RS04550	ENOG4105CQW	ribosome biogenesis GTPase YqeH
FGL66_RS04555	ENOG4105E2X	shikimate dehydrogenase
FGL66_RS04560	ENOG410812S	Rna-binding protein
FGL66_RS04570	ENOG4108WF2	Metal Dependent Phosphohydrolase
FGL66_RS04580	ENOG4105DXX	methyltransferase
FGL66_RS04585	ENOG4105KQC	Competence protein
FGL66_RS04590	ENOG4108UK2	deaminase
FGL66_RS04595	ENOG4105EGY	DNA internalization-related competence protein ComEC Rec2
FGL66_RS04600	ENOG4105TQK	DNA polymerase iii, delta' subunit
FGL66_RS04605	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
FGL66_RS04615	ENOG4105CSA	Coproporphyrinogen iii oxidase
FGL66_RS04620	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
FGL66_RS04630	ENOG4105CFG	Acts as a chaperone (By similarity)
FGL66_RS04635	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
FGL66_RS04640	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
FGL66_RS04645	ENOG4107TVK	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
FGL66_RS04650	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
FGL66_RS04665	ENOG4105DI5	UPF0365 protein
FGL66_RS04675	ENOG4105C9A	Phoh family
FGL66_RS04685	ENOG4107YR5	Diacylglycerol kinase
FGL66_RS04690	ENOG4105KG3	cytidine deaminase
FGL66_RS04695	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
FGL66_RS04700	ENOG4108SAY	Involved in DNA repair and RecF pathway recombination (By similarity)
FGL66_RS04705	ENOG4105D9H	Catalyzes the attachment of glycine to tRNA(Gly) (By similarity)
FGL66_RS04715	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
FGL66_RS04720	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
FGL66_RS04725	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
FGL66_RS04740	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
FGL66_RS04745	ENOG4105C1J	atp-dependent rna helicase
FGL66_RS04750	ENOG4105EFU	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin (By similarity)
FGL66_RS04755	ENOG4105FDK	ABC transporter
FGL66_RS04765	ENOG4105N80	Ferric uptake regulator, Fur family
FGL66_RS04770	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
FGL66_RS04775	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
FGL66_RS04780	ENOG4107RF6	penicillin-binding protein
FGL66_RS04790	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
FGL66_RS04815	ENOG4105C5X	domain protein
FGL66_RS04845	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
FGL66_RS04850	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
FGL66_RS04860	ENOG4107RGW	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FGL66_RS04865	ENOG4105WZW	rhodanese family
FGL66_RS04870	ENOG4107S5Z	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation (By similarity)
FGL66_RS04885	ENOG4105DC7	peptidase M24
FGL66_RS04890	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
FGL66_RS04900	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
FGL66_RS04905	ENOG4108ZSR	alkaline shock protein
FGL66_RS04915	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
FGL66_RS04930	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
FGL66_RS04940	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
FGL66_RS04945	ENOG4107RE7	phosphate butyryltransferase
FGL66_RS04950	ENOG4105CKM	Branched-chain carboxylic acid kinase
FGL66_RS04965	ENOG4105CPP	Dehydrogenase, E1 component
FGL66_RS04970	ENOG4105C7S	Dehydrogenase
FGL66_RS04980	ENOG4108QEG	Membrane
FGL66_RS04990	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
FGL66_RS05005	ENOG4108W3Q	Transcriptional regulator
FGL66_RS05010	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
FGL66_RS05015	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
FGL66_RS05020	ENOG4105II7	pyrroline-5-carboxylate reductase
FGL66_RS05030	ENOG4105CPC	Aldo Keto reductase
FGL66_RS05035	ENOG4108YZ4	nudix hydrolase
FGL66_RS05040	ENOG4105I3K	Ferric uptake regulator, Fur family
FGL66_RS05045	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
FGL66_RS05055	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
FGL66_RS05060	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
FGL66_RS05065	ENOG4105FE9	pseudouridine synthase
FGL66_RS05070	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
FGL66_RS05075	ENOG4105BZU	Histidine kinase
FGL66_RS05095	ENOG4105C9U	ATP-dependent DNA helicase RecQ
FGL66_RS05105	ENOG4105E4T	pyridine nucleotide-disulfide oxidoreductase
FGL66_RS05110	ENOG4107RB3	L-asparaginase
FGL66_RS05115	ENOG4105CAT	Cytidine monophosphate kinase
FGL66_RS05120	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
FGL66_RS05130	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
FGL66_RS05135	ENOG4105K70	DNA-binding protein
FGL66_RS05145	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
FGL66_RS05150	ENOG4105EAH	synthase
FGL66_RS05155	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
FGL66_RS05160	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
FGL66_RS05165	ENOG4105D49	3-dehydroquinate synthase
FGL66_RS05175	ENOG41068YB	TPR repeat-containing protein
FGL66_RS05180	ENOG4105QKB	UPF0302 protein
FGL66_RS05215	ENOG4108UXE	Protein tyrosine phosphatase
FGL66_RS05220	ENOG4105VUN	Transcriptional regulator
FGL66_RS05230	ENOG4108ZPQ	MazG nucleotide pyrophosphohydrolase
FGL66_RS05235	ENOG4105CPK	Glycosyl transferase (Group 1
FGL66_RS05240	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
FGL66_RS05250	ENOG4105DVT	helicase
FGL66_RS05255	ENOG4105C5S	asparaginyl-tRNA synthetase
FGL66_RS05265	ENOG4105CSM	endonuclease III
FGL66_RS05275	ENOG4105BZ4	penicillin-binding protein
FGL66_RS05280	ENOG4108UI2	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation (By similarity)
FGL66_RS05290	ENOG4108UKS	UPF0398 protein
FGL66_RS05295	ENOG4105XWG	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation (By similarity)
FGL66_RS05305	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
FGL66_RS05310	ENOG4105FR1	rard protein
FGL66_RS05320	ENOG410890F	Dynamin family
FGL66_RS05345	ENOG4106QQ5	PBS lyase HEAT domain protein repeat-containing protein
FGL66_RS05350	ENOG4108Y6J	UPF0403 protein
FGL66_RS05360	ENOG4108YYV	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity)
FGL66_RS05365	ENOG4108RCR	degv family
FGL66_RS05375	ENOG4105E0X	reductase
FGL66_RS05380	ENOG4105C5Y	PTS System
FGL66_RS05390	ENOG4105CN1	protease
FGL66_RS05405	ENOG410841Q	phosphoesterase PA-phosphatase related protein
FGL66_RS05410	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
FGL66_RS05415	ENOG4105GR3	Histidine kinase
FGL66_RS05420	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
FGL66_RS05440	ENOG4105GMT	ATPase associated with various cellular activities aaa_5
FGL66_RS05445	ENOG4107T89	von Willebrand factor, type A
FGL66_RS05450	ENOG4105CWM	branched-chain amino acid transport system II carrier protein
FGL66_RS05455	ENOG4108K2R	Glutathione-regulated potassium-efflux system ancillary protein
FGL66_RS05460	ENOG4105CDW	Resistance protein
FGL66_RS05490	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
FGL66_RS05495	ENOG4108XFP	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
FGL66_RS05500	ENOG4105CH2	amidohydrolase
FGL66_RS05510	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
FGL66_RS05515	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
FGL66_RS05520	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
FGL66_RS05525	ENOG4105C5H	ABC transporter
FGL66_RS05530	ENOG4105QNR	S1 RNA binding domain protein
FGL66_RS05545	ENOG4108TV1	Catalyzes the incorporation of amino acid(s) into the interchain peptide bridge of peptidoglycan, using aminoacyl-tRNA as amino acid donor (By similarity)
FGL66_RS05550	ENOG4108RMH	femAB family
FGL66_RS05555	ENOG4105EVN	Prephenate dehydrogenase
FGL66_RS05570	ENOG4108RCF	TRANSCRIPTIONal
FGL66_RS05575	ENOG4108FKN	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
FGL66_RS05595	ENOG4105CID	antiterminator
FGL66_RS05605	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
FGL66_RS05610	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
FGL66_RS05615	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
FGL66_RS05630	ENOG4108I0Z	Aconitate hydratase
FGL66_RS05635	ENOG4105C94	Transporter
FGL66_RS05640	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
FGL66_RS05650	ENOG4107RFY	SbcCD D subunit
FGL66_RS05670	ENOG4105VPS	UPF0291 protein
FGL66_RS05680	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
FGL66_RS05685	ENOG4107SJ1	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides (By similarity)
FGL66_RS05690	ENOG41082QR	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
FGL66_RS05700	ENOG4105CH6	catalase
FGL66_RS05705	ENOG4108IQI	permease
FGL66_RS05715	ENOG410667J	hydrolase
FGL66_RS05720	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
FGL66_RS05725	ENOG4108IYI	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine (By similarity)
FGL66_RS05730	ENOG4105D6E	homoserine dehydrogenase
FGL66_RS05735	ENOG4105CFH	Aspartokinase
FGL66_RS05760	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
FGL66_RS05770	ENOG4108V1J	Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity)
FGL66_RS05775	ENOG4105VK3	rdd domain containing protein
FGL66_RS05780	ENOG4105D07	Signal peptide peptidase, SppA
FGL66_RS05790	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
FGL66_RS05800	ENOG4105DGY	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization (By similarity)
FGL66_RS05820	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
FGL66_RS05825	ENOG4108X3M	OsmC Ohr family protein
FGL66_RS05830	ENOG4105C5R	Aminotransferase
FGL66_RS05835	ENOG4108JQ1	Dehydrogenase
FGL66_RS05845	ENOG4105F6E	Acyl-transferase
FGL66_RS05850	ENOG4105C0H	protease
FGL66_RS05860	ENOG4105BZ4	penicillin-binding protein
FGL66_RS05875	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
FGL66_RS05890	ENOG4105MQN	general stress protein
FGL66_RS05905	ENOG4108VDD	TRNA binding domain protein
FGL66_RS05930	ENOG4105C8F	Beta-lactamase domain protein
FGL66_RS05935	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
FGL66_RS05940	ENOG4108V15	phosphotransferase enzyme family
FGL66_RS05945	ENOG4105F0I	Aminotransferase
FGL66_RS05950	ENOG4107QSE	Dipeptidase
FGL66_RS05970	ENOG4105CBX	hi0933 family
FGL66_RS05975	ENOG41085GJ	domain protein
FGL66_RS05980	ENOG4105C8T	Leucyl-tRNA synthetase
FGL66_RS05985	ENOG410605W	Major Facilitator
FGL66_RS05990	ENOG4105N5T	Radical SAM Protein
FGL66_RS06005	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
FGL66_RS06010	ENOG4105E8V	Alpha Beta Hydrolase Fold protein
FGL66_RS06020	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
FGL66_RS06025	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
FGL66_RS06030	ENOG4108R6K	riboflavin synthase, subunit alpha
FGL66_RS06035	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
FGL66_RS06045	ENOG4108FQ0	the rest of the oligosaccharide is released intact. Cleaves the peptidoglycan connecting the daughter cells at the end of the cell division cycle, resulting in the separation of the two newly divided cells. Acts as an autolysin in penicillin-induced lysis
FGL66_RS06070	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
FGL66_RS06080	ENOG4105WMR	Protein CrcB homolog
FGL66_RS06085	ENOG4105WMR	Protein CrcB homolog
FGL66_RS06095	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
FGL66_RS06100	ENOG4105DJ1	Phosphoenolpyruvate Carboxylase
FGL66_RS06115	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
FGL66_RS06130	ENOG4108KN7	Removes 5-oxoproline from various penultimate amino acid residues except L-proline (By similarity)
FGL66_RS06165	ENOG4105EYG	tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site (By similarity)
FGL66_RS06215	ENOG4105C1Q	protoporphyrinogen oxidase
FGL66_RS06220	ENOG4107TTW	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
FGL66_RS06225	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
FGL66_RS06230	ENOG4105Q24	Signal transduction protein, which is a major regulator of staphylococcal pathogenesis. Phosphorylated TRAP leads to the activation of agr system and consequent RNAIII synthesis resulting in the expression of several virulence factors. Upregulates the expression of most toxins and genes known to be necessary for biofilm formation
FGL66_RS06245	ENOG4105K59	histidine triad (HIT) protein
FGL66_RS06265	ENOG4107XMQ	Peptidyl-prolyl cis-trans isomerase
FGL66_RS06270	ENOG4105EQI	Metal Dependent Phosphohydrolase
FGL66_RS06280	ENOG4107VRP	DNA repair exonuclease
FGL66_RS06285	ENOG4105WZB	UPF0342 protein
FGL66_RS06290	ENOG4108UH6	UPF0754 membrane protein
FGL66_RS06310	ENOG4105WH1	Two component transcriptional regulator luxr family
FGL66_RS06315	ENOG4105BZU	Histidine kinase
FGL66_RS06320	ENOG4108YBP	pseudouridine synthase
FGL66_RS06325	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
FGL66_RS06330	ENOG4107R33	ppx gppa phosphatase
FGL66_RS06335	ENOG4105C9Q	fumarate hydratase class II
FGL66_RS06350	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
FGL66_RS06355	ENOG4105CE4	GlcNAc 6-P deacetylase
FGL66_RS06365	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
FGL66_RS06370	ENOG4105CDA	abc transporter atp-binding protein
FGL66_RS06375	ENOG4105E5Q	amino acid AbC transporter
FGL66_RS06525	ENOG4105G5W	regulator Fur family
FGL66_RS06530	ENOG4105C5I	Dehydrogenase
FGL66_RS06535	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FGL66_RS06540	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
FGL66_RS06555	ENOG4107NBY	Membrane
FGL66_RS06565	ENOG4105EVI	UPF0374 protein
FGL66_RS06570	ENOG4105CEN	a g-specific adenine glycosylase
FGL66_RS06575	ENOG41067AE	Membrane-bound metal-dependent hydrolase
FGL66_RS06585	ENOG4105EY8	ABC transporter
FGL66_RS06595	ENOG410902V	Modulates RecA activity (By similarity)
FGL66_RS06600	ENOG4105BZ4	penicillin-binding protein
FGL66_RS06605	ENOG4108RMH	femAB family
FGL66_RS06610	ENOG4108Z0Z	intracellular protease Pfpi family
FGL66_RS06625	ENOG4108S4H	thioesterase Superfamily protein
FGL66_RS06640	ENOG4107ZCW	Low molecular weight phosphotyrosine protein phosphatase
FGL66_RS06650	ENOG4107U9T	Pfam:Ribonuclease_BN
FGL66_RS06655	ENOG4108V2W	Carbonate dehydratase
FGL66_RS06660	ENOG4105WH1	Two component transcriptional regulator luxr family
FGL66_RS06665	ENOG4105ENE	Histidine kinase
FGL66_RS06680	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
FGL66_RS06685	ENOG4108V3A	UPF0421 protein
FGL66_RS06700	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
FGL66_RS06715	ENOG41090A1	ferritin
FGL66_RS06725	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
FGL66_RS06735	ENOG4105IJJ	transcriptional regulator, crp fnr family
FGL66_RS06755	ENOG4108WZA	zeta toxin
FGL66_RS06765	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
FGL66_RS06770	ENOG4105CBD	Diacylglycerol kinase
FGL66_RS06775	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
FGL66_RS06785	ENOG4105VB5	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
FGL66_RS06790	ENOG4105CK7	Sodium proline symporter
FGL66_RS06795	ENOG4108S01	response regulator
FGL66_RS06805	ENOG4105KCT	ABC transporter
FGL66_RS06810	ENOG4108M15	ABC transporter
FGL66_RS06815	ENOG4105EW6	flavin reductase domain protein, FMN-binding
FGL66_RS06825	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
FGL66_RS06830	ENOG4105C4R	Atp-dependent dna helicase
FGL66_RS06840	ENOG4105KGF	protein, YerC YecD
FGL66_RS06855	ENOG4108U5N	UPF0316 protein
FGL66_RS06860	ENOG4107RA1	nh(3)-dependent nad( ) synthetase
FGL66_RS06865	ENOG4105DAP	Nicotinate phosphoribosyltransferase
FGL66_RS06875	ENOG4105CQC	Prephenate dehydratase
FGL66_RS06895	ENOG4105E2M	Manganese-dependent inorganic pyrophosphatase
FGL66_RS06905	ENOG4105C26	Dehydrogenase
FGL66_RS06910	ENOG4105HHQ	6-phosphogluconolactonase (EC 3.1.1.31)
FGL66_RS06940	ENOG4105C6Z	Gluconate
FGL66_RS06945	ENOG4105CMG	Carbohydrate kinase
FGL66_RS06960	ENOG4105CJ1	ABC, transporter
FGL66_RS06985	ENOG410811P	TRANSCRIPTIONAl REGULATOR GntR family
FGL66_RS07000	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
FGL66_RS07015	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
FGL66_RS07030	ENOG4105CQP	nitrilase cyanide hydratase and apolipoprotein n-acyltransferase
FGL66_RS07060	ENOG4105D7K	pfkb domain protein
FGL66_RS07080	ENOG4105CUC	YeeE YedE family protein
FGL66_RS07090	ENOG4105C5H	ABC transporter
FGL66_RS07095	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
FGL66_RS07100	ENOG410801F	ribosomal-protein-alanine acetyltransferase
FGL66_RS07105	ENOG41072GX	Peptidase M22 Glycoprotease
FGL66_RS07110	ENOG4105K8N	protein family UPF0079, ATPase
FGL66_RS07115	ENOG4105C01	Dihydroxy-acid dehydratase
FGL66_RS07120	ENOG4105C7K	acetolactate synthase
FGL66_RS07135	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
FGL66_RS07140	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
FGL66_RS07145	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
FGL66_RS07150	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
FGL66_RS07195	ENOG4108ZBE	Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition (By similarity)
FGL66_RS07200	ENOG4105WN5	stage II sporulation protein
FGL66_RS07205	ENOG4107SGM	protein serine threonine phosphatase
FGL66_RS07210	ENOG4108YZM	Toxic component of a toxin-antitoxin (TA) module (By similarity)
FGL66_RS07245	ENOG4105C1J	atp-dependent rna helicase
FGL66_RS07250	ENOG4107EES	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity)
FGL66_RS07255	ENOG4105CPF	Cell wall formation (By similarity)
FGL66_RS07265	ENOG4105C59	p-type ATPase
FGL66_RS07270	ENOG41082MP	copper ion binding protein
FGL66_RS07280	ENOG4105VPX	protein, conserved in bacteria
FGL66_RS07285	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
FGL66_RS07295	ENOG4107XQC	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins (By similarity)
FGL66_RS07300	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
FGL66_RS07315	ENOG4108UUM	single-stranded DNA-binding protein
FGL66_RS07325	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
FGL66_RS07335	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
FGL66_RS07340	ENOG4106778	Protein of unknown function (DUF1146)
FGL66_RS07355	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
FGL66_RS07360	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
FGL66_RS07365	ENOG4107YZM	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
FGL66_RS07370	ENOG4107ZFM	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) (By similarity)
FGL66_RS07375	ENOG4105WS6	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
FGL66_RS07380	ENOG4107RFS	it plays a direct role in the translocation of protons across the membrane (By similarity)
FGL66_RS07390	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
FGL66_RS07395	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
FGL66_RS07400	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
FGL66_RS07405	ENOG4108UIC	UPF0340 protein
FGL66_RS07410	ENOG4107WAU	Protein tyrosine phosphatase
FGL66_RS07415	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
FGL66_RS07420	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
FGL66_RS07425	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
FGL66_RS07435	ENOG41082DI	50s ribosomal protein l31
FGL66_RS07440	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
FGL66_RS07445	ENOG4105C26	Dehydrogenase
FGL66_RS07455	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
FGL66_RS07460	ENOG4105D2N	Aldolase
FGL66_RS07475	ENOG4105CXY	transporter
FGL66_RS07495	ENOG4105HNY	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
FGL66_RS07515	ENOG4106762	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) (By similarity)
FGL66_RS07530	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
FGL66_RS07535	ENOG4108RVA	ribokinase
FGL66_RS07545	ENOG4105DFD	Na H antiporter
FGL66_RS07560	ENOG4105JXH	GntR family transcriptional regulator
FGL66_RS07575	ENOG4105DKW	ABC transporter
FGL66_RS07595	ENOG4105C8B	TIGR00159 family
FGL66_RS07600	ENOG4105CYW	agmatinase
FGL66_RS07650	ENOG4105D1F	ATP-binding protein
FGL66_RS07670	ENOG4108UT2	hemolysin iii
FGL66_RS07675	ENOG4108MYC	UTP-glucose-1-phosphate uridylyltransferase
FGL66_RS07680	ENOG4107K5X	Membrane-bound metal-dependent hydrolase
FGL66_RS07685	ENOG4107DUR	UPF0457 protein
FGL66_RS07690	ENOG4105DWD	nucleoside recognition domain protein
FGL66_RS07695	ENOG4108U1V	ABC transporter, permease
FGL66_RS07700	ENOG4105DQ5	transport system permease protein
FGL66_RS07705	ENOG4108HUF	Transporter
FGL66_RS07710	ENOG4106M28	alanine racemase domain protein
FGL66_RS07720	ENOG4107SFI	Major Facilitator superfamily
FGL66_RS07730	ENOG4105F27	Major Facilitator
FGL66_RS07735	ENOG4105VBF	alkaline shock protein
FGL66_RS07750	ENOG4105CS2	ec 3.2.1.21
FGL66_RS07760	ENOG4108S3Y	transcriptional regulator
FGL66_RS07780	ENOG4108YBA	Histidine kinase
FGL66_RS07785	ENOG4105CDA	abc transporter atp-binding protein
FGL66_RS07790	ENOG4105DRP	amino acid AbC transporter
FGL66_RS07805	ENOG4105CB5	ATP-dependent DNA helicase recG
FGL66_RS07810	ENOG4108UJD	30S ribosomal protein S9
FGL66_RS07820	ENOG4105D7A	ATP-binding protein
FGL66_RS07850	ENOG4108UJD	30S ribosomal protein S9
FGL66_RS07860	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
FGL66_RS07870	ENOG4108JJB	ABC transporter
FGL66_RS07880	ENOG4108ZT0	50S ribosomal protein l17
FGL66_RS07885	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
FGL66_RS07890	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
FGL66_RS07910	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
FGL66_RS07915	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
FGL66_RS07925	ENOG4105VPB	50S ribosomal protein L30
FGL66_RS07930	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
FGL66_RS07940	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
FGL66_RS07945	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
FGL66_RS07950	ENOG41082QR	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
FGL66_RS07960	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
FGL66_RS07965	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
FGL66_RS07975	ENOG41082SA	50s ribosomal protein l29
FGL66_RS07985	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
FGL66_RS07990	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
FGL66_RS07995	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
FGL66_RS08000	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FGL66_RS08005	ENOG41080UE	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
FGL66_RS08010	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
FGL66_RS08015	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
FGL66_RS08030	ENOG4105C7N	Xanthine uracil vitamin C permease
FGL66_RS08065	ENOG4108TV1	Catalyzes the incorporation of amino acid(s) into the interchain peptide bridge of peptidoglycan, using aminoacyl-tRNA as amino acid donor (By similarity)
FGL66_RS08075	ENOG41065XD	Transcriptional regulator
FGL66_RS08080	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
FGL66_RS08085	ENOG41082CS	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
FGL66_RS08095	ENOG4108ZAF	Molybdopterin
FGL66_RS08105	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
FGL66_RS08115	ENOG4105EPU	Molybdenum cofactor synthesis domain protein
FGL66_RS08120	ENOG4105D06	uba thif-type nad fad binding protein
FGL66_RS08125	ENOG4105CGB	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity)
FGL66_RS08130	ENOG4105E0C	molybdate abc transporter
FGL66_RS08135	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
FGL66_RS08160	ENOG4105DZ1	carboxypeptidase
FGL66_RS08180	ENOG4107ZYJ	bioY protein
FGL66_RS08190	ENOG4107YCY	Transcriptional regulator
FGL66_RS08200	ENOG4107RJ1	sodium solute
FGL66_RS08210	ENOG4105WD1	Membrane
FGL66_RS08215	ENOG4105FDT	acyl-CoA dehydrogenase
FGL66_RS08275	ENOG4108HIZ	formate dehydrogenase alpha subunit
FGL66_RS08280	ENOG4108KGH	TRANSCRIPTIONal
FGL66_RS08320	ENOG4107YBY	Hydrolase
FGL66_RS08335	ENOG4105C09	Bile acid
FGL66_RS08360	ENOG4105CHH	sulfate transporter
FGL66_RS08365	ENOG4105CI2	imidazolone-5-propionate hydrolase
FGL66_RS08370	ENOG4105CGP	Urocanate hydratase
FGL66_RS08375	ENOG4105DWD	nucleoside recognition domain protein
FGL66_RS08380	ENOG4105DND	Transcriptional regulator
FGL66_RS08395	ENOG4105E66	phosphoriboisomerase A
FGL66_RS08405	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
FGL66_RS08410	ENOG4105KK4	UPF0060 membrane protein
FGL66_RS08415	ENOG4105RHA	ABC transporter, permease
FGL66_RS08420	ENOG4108IUX	(ABC) transporter
FGL66_RS08440	ENOG4105KAF	membrAne
FGL66_RS08445	ENOG4108VX5	3-methyladenine DNA glycosylase
FGL66_RS08475	ENOG4105D6U	Sodium Glutamate Symporter
FGL66_RS08480	ENOG4105CKI	cobalamin synthesis protein
FGL66_RS08505	ENOG4105ETU	transcriptional activator (TenA
FGL66_RS08525	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
FGL66_RS08530	ENOG4105I2S	Part of the ABC transporter complex hrt involved in hemin import. Responsible for the translocation of the substrate across the membrane (By similarity)
FGL66_RS08540	ENOG4105BZU	Histidine kinase
FGL66_RS08545	ENOG4105DWT	malate dehydrogenase (quinone)
FGL66_RS08575	ENOG4105CAY	ferredoxin--nadp reductase
FGL66_RS08615	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
FGL66_RS08630	ENOG4108UZ3	Transporter
FGL66_RS08635	ENOG4105CN9	Peptidase m42 family protein
FGL66_RS08650	ENOG4105DQQ	Major facilitator superfamily MFS_1
FGL66_RS08655	ENOG4105WH1	Two component transcriptional regulator luxr family
FGL66_RS08660	ENOG4105BZU	Histidine kinase
FGL66_RS08675	ENOG4105R3A	Nitrate reductase
FGL66_RS08680	ENOG4108IUE	nitrate reductase beta subunit
FGL66_RS08690	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
FGL66_RS08695	ENOG4105KH3	nitrite reductase (NAD(P)h) small subunit
FGL66_RS08700	ENOG4108IFG	nitrite reductase, (NAD(P)H)
FGL66_RS08705	ENOG41087GM	Siroheme synthase (Precorrin-2 oxidase ferrochelatase domain)-like protein
FGL66_RS08715	ENOG4108XSB	acetyltransferase, (GNAT) family
FGL66_RS08730	ENOG4107QPK	)-transporter
FGL66_RS08745	ENOG4105EJQ	L-serine dehydratase
FGL66_RS08765	ENOG4105F1A	Pyruvate formate-lyase
FGL66_RS08790	ENOG4105E5Q	amino acid AbC transporter
FGL66_RS08805	ENOG4105BZW	Glycerate kinase
FGL66_RS08810	ENOG4108Z6X	(sortase) family
FGL66_RS08815	ENOG4108UW5	maltose o-acetyltransferase
FGL66_RS08820	ENOG4105DJB	Major Facilitator Superfamily
FGL66_RS08825	ENOG4105DMC	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 3
FGL66_RS08830	ENOG4105BZG	amino acid carrier protein
FGL66_RS08835	ENOG4105BZ1	(ABC) transporter
FGL66_RS08840	ENOG4105BZ1	(ABC) transporter
FGL66_RS08850	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
FGL66_RS08855	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
FGL66_RS08865	ENOG4105DK0	Indole-3-glycerol phosphate synthase
FGL66_RS08870	ENOG4108I0Q	anthranilate phosphoribosyltransferase
FGL66_RS08875	ENOG4105DDQ	anthranilate synthase
FGL66_RS08880	ENOG4105CRQ	synthase (Component I)
FGL66_RS08885	ENOG4105CFM	UPF0317 protein
FGL66_RS08890	ENOG4105HMI	Membrane
FGL66_RS08905	ENOG4108IXP	Carbohydrate diacid transcriptional activator CdaR
FGL66_RS08920	ENOG4105E09	nadh pyrophosphatase
FGL66_RS08930	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
FGL66_RS08945	ENOG4105C2C	drug resistance transporter, Bcr CflA
FGL66_RS08950	ENOG4107VWA	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation (By similarity)
FGL66_RS08960	ENOG4105CSR	polyphosphate kinase 2
FGL66_RS08985	ENOG4108TVJ	Nitroreductase
FGL66_RS08990	ENOG4105K56	Transcriptional regulator
FGL66_RS09005	ENOG4108IPW	abc transporter atp-binding protein
FGL66_RS09010	ENOG4105CM4	permease protein
FGL66_RS09015	ENOG4105DHS	permease protein
FGL66_RS09025	ENOG41067MG	lrgb family
FGL66_RS09035	ENOG4105CMU	LysR family (Transcriptional regulator
FGL66_RS09040	ENOG4105K78	MarR family Transcriptional regulator
FGL66_RS09050	ENOG4105PGM	cation diffusion facilitator family transporter
FGL66_RS09055	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
FGL66_RS09060	ENOG4105C19	ABC transporter
FGL66_RS09075	ENOG4108RCM	Nitroreductase
FGL66_RS09090	ENOG4108NMT	An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon (By similarity)
FGL66_RS09100	ENOG4107RZX	Teichoic acid biosynthesis protein
FGL66_RS09105	ENOG4105EJJ	Dehydrogenase
FGL66_RS09110	ENOG4108QHG	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
FGL66_RS09135	ENOG4108S4A	n-acetylmuramoyl-l-alanine amidase
FGL66_RS09140	ENOG4108Z6Z	Transcriptional regulator
FGL66_RS09145	ENOG4107SKW	Inherit from COG: Alpha beta hydrolase
FGL66_RS09155	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
FGL66_RS09160	ENOG4105VDH	Dihydroxyacetone kinase
FGL66_RS09165	ENOG4108UTZ	Dihydroxyacetone kinase
FGL66_RS09170	ENOG4105CMT	Dihydroxyacetone kinase
FGL66_RS09175	ENOG4105CZG	Phosphotransfer between the C1 and C5 carbon atoms of pentose (By similarity)
FGL66_RS09180	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
FGL66_RS09190	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
FGL66_RS09195	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
FGL66_RS09200	ENOG4105CIH	Imidazole acetol-phosphate transaminase
FGL66_RS09205	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
FGL66_RS09215	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
FGL66_RS09220	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
FGL66_RS09225	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
FGL66_RS09240	ENOG4105TRT	Transcriptional regulator
FGL66_RS09245	ENOG4105C94	Transporter
FGL66_RS09250	ENOG4108RPX	mosc domain containing protein
FGL66_RS09255	ENOG4107FQX	Alpha-acetolactate decarboxylase
FGL66_RS09260	ENOG4105G6Z	alkaline phosphatase
FGL66_RS09265	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
FGL66_RS09270	ENOG4105DVA	methyltransferase
FGL66_RS09275	ENOG4105DU0	nucleoside hydrolase
FGL66_RS09280	ENOG4105DS2	Anaerobic c4-dicarboxylate transporter
FGL66_RS09285	ENOG4105EMU	Dehydrogenase
FGL66_RS09295	ENOG4105CHR	reductase
FGL66_RS09300	ENOG4105DSE	periplasmic solute binding protein
FGL66_RS09305	ENOG4108RDD	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine (By similarity)
FGL66_RS09310	ENOG4105CJD	(Anaerobic) ribonucleoside-triphosphate reductase
FGL66_RS09325	ENOG4105DUY	Ser-Asp rich fibrinogen-binding, bone sialoprotein-binding protein
FGL66_RS09330	ENOG4105DUY	Ser-Asp rich fibrinogen-binding, bone sialoprotein-binding protein
FGL66_RS09350	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
FGL66_RS09375	ENOG4105C28	cystathionine
FGL66_RS09385	ENOG4105EBR	Carboxylesterase
FGL66_RS09390	ENOG4105C8J	)-transporter
FGL66_RS09400	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
FGL66_RS09405	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
FGL66_RS09450	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
FGL66_RS09455	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
FGL66_RS09460	ENOG4105C2W	permease
FGL66_RS09465	ENOG4108UPS	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis (By similarity)
FGL66_RS09485	ENOG4107R6U	sodium dicarboxylate symporter
FGL66_RS09490	ENOG4108DBC	nitroreductase
FGL66_RS09500	ENOG4105D3R	alkyl hydroperoxide reductase
FGL66_RS09505	ENOG4108JU3	Alkyl hydroperoxide reductase
FGL66_RS09515	ENOG4105D01	(LipO)protein
FGL66_RS09520	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
FGL66_RS09530	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
FGL66_RS09535	ENOG4108UMI	ABC transporter, permease
FGL66_RS09540	ENOG4105D01	(LipO)protein
FGL66_RS09550	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
FGL66_RS09555	ENOG4108UUM	single-stranded DNA-binding protein
FGL66_RS09560	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
FGL66_RS09565	ENOG4105C3G	gtp-binding protein
FGL66_RS09570	ENOG4105VDK	protein, conserved in bacteria
FGL66_RS09575	ENOG4105D8X	mechanosensitive ion channel
FGL66_RS09580	ENOG4105FA0	parb-like partition protein
FGL66_RS09585	ENOG4105C28	cystathionine
FGL66_RS09590	ENOG4105C28	cystathionine
FGL66_RS09615	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
FGL66_RS09620	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
FGL66_RS09625	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
FGL66_RS09630	ENOG4105M7T	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)