locus-tag	class	description
D3P10_RS00020	COG1230	cation diffusion facilitator family transporter
D3P10_RS00030	COG1937	Protein conserved in bacteria
D3P10_RS00035	COG2217	Heavy metal translocating P-type atpase
D3P10_RS00110	COG1131	(ABC) transporter
D3P10_RS00130	COG3682	Transcriptional regulator
D3P10_RS00140	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
D3P10_RS00145	COG0592	DNA-directed DNA polymerase activity
D3P10_RS00150	COG2501	S4 domain
D3P10_RS00155	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
D3P10_RS00160	COG0187	DNA topoisomerase II activity
D3P10_RS00165	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
D3P10_RS00170	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
D3P10_RS00185	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
D3P10_RS00195	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
D3P10_RS00210	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
D3P10_RS00215	COG0359	binds to the 23S rRNA
D3P10_RS00220	COG0305	Participates in initiation and elongation during chromosome replication
D3P10_RS00240	COG0745	RESPONSE REGULATOR receiver
D3P10_RS00245	COG5002	protein histidine kinase activity
D3P10_RS00250	COG4863	YycH protein
D3P10_RS00260	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
D3P10_RS00270	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
D3P10_RS00300	COG0542	response to heat
D3P10_RS00305	COG3223	Belongs to the PsiE family
D3P10_RS00320	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
D3P10_RS00325	COG1733	regulation of RNA biosynthetic process
D3P10_RS00355	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
D3P10_RS00370	COG1012	belongs to the aldehyde dehydrogenase family
D3P10_RS00380	COG2851	Citrate transporter
D3P10_RS00385	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
D3P10_RS00390	COG0300	oxidoreductase activity
D3P10_RS00395	COG2814	Major facilitator Superfamily
D3P10_RS00400	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
D3P10_RS00405	COG2226	methyltransferase
D3P10_RS00430	COG2808	Putative FMN-binding domain
D3P10_RS00435	COG0110	maltose O-acetyltransferase activity
D3P10_RS00440	COG1114	Component of the transport system for branched-chain amino acids
D3P10_RS00445	COG2814	Major facilitator Superfamily
D3P10_RS00490	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
D3P10_RS00500	COG1609	Transcriptional regulator
D3P10_RS00510	COG1869	D-ribose catabolic process
D3P10_RS00530	COG2814	Major facilitator Superfamily
D3P10_RS00550	COG1131	(ABC) transporter
D3P10_RS00580	COG0601	transmembrane transport
D3P10_RS00590	COG0444	Belongs to the ABC transporter superfamily
D3P10_RS00595	COG1124	(ABC) transporter
D3P10_RS00610	COG0346	lactoylglutathione lyase activity
D3P10_RS00620	COG1518	maintenance of DNA repeat elements
D3P10_RS00645	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
D3P10_RS00645	COG3711	transcriptional antiterminator
D3P10_RS00650	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
D3P10_RS00650	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
D3P10_RS00650	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
D3P10_RS00655	COG1482	cell wall glycoprotein biosynthetic process
D3P10_RS00660	COG0706	membrane insertase activity
D3P10_RS00690	COG1250	3-hydroxyacyl-CoA dehydrogenase
D3P10_RS00695	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
D3P10_RS00715	COG2235	arginine
D3P10_RS00720	COG1438	arginine binding
D3P10_RS00725	COG0659	secondary active sulfate transmembrane transporter activity
D3P10_RS00745	COG0438	transferase activity, transferring glycosyl groups
D3P10_RS00750	COG0653	protein targeting
D3P10_RS00760	COG1073	alpha beta
D3P10_RS00770	COG0201	protein transport
D3P10_RS00785	COG0747	negative chemotaxis
D3P10_RS00790	COG0601	transmembrane transport
D3P10_RS00795	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
D3P10_RS00805	COG1124	(ABC) transporter
D3P10_RS00810	COG0789	Transcriptional regulator
D3P10_RS00815	COG0656	L-ascorbic acid biosynthetic process
D3P10_RS00830	COG2259	Doxx family
D3P10_RS00840	COG1959	2 iron, 2 sulfur cluster binding
D3P10_RS00845	COG2910	NAD(P)H-binding
D3P10_RS00850	COG1876	peptidase activity
D3P10_RS00855	COG1882	Formate acetyltransferase
D3P10_RS00860	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
D3P10_RS00870	COG1288	antiporter activity
D3P10_RS00885	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
D3P10_RS00935	COG1785	Belongs to the alkaline phosphatase family
D3P10_RS00970	COG0745	RESPONSE REGULATOR receiver
D3P10_RS00975	COG1131	(ABC) transporter
D3P10_RS00985	COG2205	protein histidine kinase activity
D3P10_RS00995	COG2720	vancomycin resistance protein
D3P10_RS01000	COG1136	(ABC) transporter
D3P10_RS01015	COG4221	oxidoreductase activity
D3P10_RS01020	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
D3P10_RS01025	COG3478	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
D3P10_RS01030	COG2962	Rard protein
D3P10_RS01035	COG0471	metal ion transport
D3P10_RS01045	COG1695	Transcriptional regulator
D3P10_RS01060	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
D3P10_RS01065	COG1054	Belongs to the UPF0176 family
D3P10_RS01090	COG1288	antiporter activity
D3P10_RS01095	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
D3P10_RS01100	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
D3P10_RS01115	COG2814	Major facilitator Superfamily
D3P10_RS01120	COG0737	Belongs to the 5'-nucleotidase family
D3P10_RS01135	COG3639	organic phosphonate transmembrane transporter activity
D3P10_RS01190	COG0477	Major facilitator Superfamily
D3P10_RS01195	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
D3P10_RS01215	COG2113	Glycine betaine
D3P10_RS01220	COG2409	Drug exporters of the RND superfamily
D3P10_RS01225	COG1764	response to oxidative stress
D3P10_RS01235	COG1705	Flagellar rod assembly protein muramidase FlgJ
D3P10_RS01235	COG3942	CHAP domain
D3P10_RS01255	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
D3P10_RS01265	COG0739	heme binding
D3P10_RS01270	COG3227	Zinc metalloprotease (Elastase)
D3P10_RS01275	COG2843	Capsule synthesis protein
D3P10_RS01290	COG3961	Belongs to the TPP enzyme family
D3P10_RS01300	COG4195	phage-related replication protein
D3P10_RS01310	COG1785	Belongs to the alkaline phosphatase family
D3P10_RS01315	COG0745	RESPONSE REGULATOR receiver
D3P10_RS01320	COG2205	protein histidine kinase activity
D3P10_RS01325	COG1136	(ABC) transporter
D3P10_RS01355	COG0175	sulfate reduction
D3P10_RS01360	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
D3P10_RS01365	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
D3P10_RS01380	COG0730	response to heat
D3P10_RS01385	COG2046	Belongs to the sulfate adenylyltransferase family
D3P10_RS01390	COG0529	Catalyzes the synthesis of activated sulfate
D3P10_RS01400	COG3942	CHAP domain
D3P10_RS01405	COG1328	CTP reductase activity
D3P10_RS01410	COG0602	queuosine metabolic process
D3P10_RS01415	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
D3P10_RS01425	COG1510	regulation of RNA biosynthetic process
D3P10_RS01430	COG1012	belongs to the aldehyde dehydrogenase family
D3P10_RS01435	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
D3P10_RS01440	COG1473	amidohydrolase
D3P10_RS01460	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
D3P10_RS01465	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
D3P10_RS01465	COG0574	Belongs to the PEP-utilizing enzyme family
D3P10_RS01470	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
D3P10_RS01475	COG0579	oxidoreductase
D3P10_RS01480	COG2188	Transcriptional regulator
D3P10_RS01485	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D3P10_RS01485	COG1263	PTS System
D3P10_RS01485	COG2190	(PTS) system
D3P10_RS01490	COG2723	6-phospho-beta-galactosidase activity
D3P10_RS01500	COG1695	Transcriptional regulator
D3P10_RS01510	COG3588	fructose-bisphosphate aldolase
D3P10_RS01520	COG0446	pyridine nucleotide-disulphide oxidoreductase
D3P10_RS01545	COG0531	amino acid
D3P10_RS01555	COG0583	DNA-binding transcription factor activity
D3P10_RS01560	COG0039	L-malate dehydrogenase activity
D3P10_RS01565	COG0028	Belongs to the TPP enzyme family
D3P10_RS01570	COG3527	Alpha-acetolactate decarboxylase
D3P10_RS01580	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
D3P10_RS01585	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
D3P10_RS01600	COG4640	response to antibiotic
D3P10_RS01630	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
D3P10_RS01640	COG0167	dihydroorotate dehydrogenase activity
D3P10_RS01650	COG0596	Alpha beta hydrolase
D3P10_RS01660	COG4221	oxidoreductase activity
D3P10_RS01695	COG1113	amino acid transport
D3P10_RS01720	COG3179	chitinase
D3P10_RS01730	COG3942	CHAP domain
D3P10_RS01750	COG0436	Aminotransferase
D3P10_RS01760	COG2608	mercury ion transmembrane transporter activity
D3P10_RS01775	COG1028	Short-chain dehydrogenase reductase Sdr
D3P10_RS01785	COG1012	belongs to the aldehyde dehydrogenase family
D3P10_RS01815	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
D3P10_RS01820	COG3425	synthase
D3P10_RS01830	COG1388	LysM domain
D3P10_RS01830	COG3942	CHAP domain
D3P10_RS01840	COG0583	DNA-binding transcription factor activity
D3P10_RS01845	COG1380	Effector of murein hydrolase LrgA
D3P10_RS01850	COG1346	cytolysis
D3P10_RS01855	COG0028	Belongs to the TPP enzyme family
D3P10_RS01875	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D3P10_RS01880	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
D3P10_RS01895	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
D3P10_RS01905	COG2843	Capsule synthesis protein
D3P10_RS01925	COG1070	Carbohydrate kinase
D3P10_RS01935	COG1760	l-serine dehydratase
D3P10_RS01940	COG1760	l-serine dehydratase
D3P10_RS01955	COG3764	Sortase (surface protein transpeptidase)
D3P10_RS01960	COG0561	phosphatase activity
D3P10_RS01970	COG0778	Nitroreductase
D3P10_RS01975	COG1012	belongs to the aldehyde dehydrogenase family
D3P10_RS01995	COG2314	TM2 domain
D3P10_RS02000	COG2514	catechol 2,3-dioxygenase activity
D3P10_RS02015	COG0583	DNA-binding transcription factor activity
D3P10_RS02020	COG1012	belongs to the aldehyde dehydrogenase family
D3P10_RS02025	COG3949	Membrane
D3P10_RS02035	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
D3P10_RS02040	COG0586	Pfam SNARE associated Golgi protein
D3P10_RS02045	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
D3P10_RS02050	COG2022	thiamine diphosphate biosynthetic process
D3P10_RS02065	COG0352	thiamine-phosphate diphosphorylase activity
D3P10_RS02070	COG2271	Major facilitator Superfamily
D3P10_RS02075	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
D3P10_RS02085	COG4876	unkown
D3P10_RS02090	COG2357	RelA SpoT domain protein
D3P10_RS02100	COG1802	Transcriptional regulator
D3P10_RS02105	COG1070	Carbohydrate kinase
D3P10_RS02110	COG2610	gluconate transmembrane transporter activity
D3P10_RS02115	COG1210	Utp--glucose-1-phosphate uridylyltransferase
D3P10_RS02125	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
D3P10_RS02130	COG0438	transferase activity, transferring glycosyl groups
D3P10_RS02135	COG0494	nUDIX hydrolase
D3P10_RS02145	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
D3P10_RS02150	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
D3P10_RS02155	COG0022	dehydrogenase e1 component
D3P10_RS02160	COG0508	dehydrogenase complex catalyzes the overall conversion of
D3P10_RS02190	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
D3P10_RS02195	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
D3P10_RS02205	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
D3P10_RS02210	COG1028	Short-chain dehydrogenase reductase Sdr
D3P10_RS02220	COG4808	Protein conserved in bacteria
D3P10_RS02225	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
D3P10_RS02240	COG0069	glutamate synthase activity
D3P10_RS02255	COG4619	ABC transporter
D3P10_RS02260	COG0390	transport system, permease component
D3P10_RS02265	COG2205	protein histidine kinase activity
D3P10_RS02270	COG0745	RESPONSE REGULATOR receiver
D3P10_RS02285	COG2814	Major facilitator Superfamily
D3P10_RS02290	COG2272	Belongs to the type-B carboxylesterase lipase family
D3P10_RS02295	COG0531	amino acid
D3P10_RS02300	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
D3P10_RS02325	COG1174	glycine betaine transport
D3P10_RS02330	COG1346	cytolysis
D3P10_RS02335	COG1380	Effector of murein hydrolase LrgA
D3P10_RS02345	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
D3P10_RS02355	COG3477	response to acidic pH
D3P10_RS02365	COG0706	membrane insertase activity
D3P10_RS02375	COG0531	amino acid
D3P10_RS02385	COG1113	amino acid transport
D3P10_RS02390	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
D3P10_RS02405	COG2814	Major facilitator Superfamily
D3P10_RS02415	COG1929	Belongs to the glycerate kinase type-1 family
D3P10_RS02430	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
D3P10_RS02435	COG0741	lytic transglycosylase activity
D3P10_RS02440	COG0588	phosphoglycerate mutase activity
D3P10_RS02450	COG2814	Major facilitator Superfamily
D3P10_RS02455	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D3P10_RS02460	COG0765	amino acid transport
D3P10_RS02465	COG1126	abc transporter atp-binding protein
D3P10_RS02470	COG2348	transferase activity, transferring amino-acyl groups
D3P10_RS02485	COG0803	Belongs to the bacterial solute-binding protein 9 family
D3P10_RS02505	COG0454	-acetyltransferase
D3P10_RS02510	COG0747	negative chemotaxis
D3P10_RS02520	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
D3P10_RS02525	COG2146	nitrite reductase [NAD(P)H] activity
D3P10_RS02535	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
D3P10_RS02540	COG1140	nitrate reductase beta subunit
D3P10_RS02550	COG2181	nitrate reductase activity
D3P10_RS02560	COG4585	Histidine kinase
D3P10_RS02570	COG2223	nitrite transmembrane transporter activity
D3P10_RS02585	COG0778	Nitroreductase
D3P10_RS02595	COG1301	dicarboxylic acid transport
D3P10_RS02620	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D3P10_RS02620	COG1263	PTS System
D3P10_RS02645	COG1028	Short-chain dehydrogenase reductase Sdr
D3P10_RS02650	COG0583	DNA-binding transcription factor activity
D3P10_RS02660	COG1028	Short-chain dehydrogenase reductase Sdr
D3P10_RS02690	COG0492	ferredoxin-NADP+ reductase activity
D3P10_RS02695	COG0456	acetyltransferase
D3P10_RS02700	COG0604	alcohol dehydrogenase
D3P10_RS02705	COG2822	iron ion transport
D3P10_RS02710	COG2837	iron assimilation
D3P10_RS02715	COG0672	)-iron permease
D3P10_RS02720	COG0805	protein transport
D3P10_RS02725	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
D3P10_RS02735	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
D3P10_RS02735	COG0463	Glycosyl transferase, family 2
D3P10_RS02745	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
D3P10_RS02745	COG0463	Glycosyl transferase, family 2
D3P10_RS02750	COG1620	l-lactate permease
D3P10_RS02755	COG0438	transferase activity, transferring glycosyl groups
D3P10_RS02760	COG0579	oxidoreductase
D3P10_RS02785	COG0577	efflux transmembrane transporter activity
D3P10_RS02810	COG2814	Major facilitator Superfamily
D3P10_RS02820	COG1566	PFAM secretion protein HlyD family protein
D3P10_RS02825	COG2814	Major facilitator Superfamily
D3P10_RS02850	COG0598	Magnesium transport protein CorA
D3P10_RS02855	COG1304	FMN binding
D3P10_RS02860	COG0786	glutamate:sodium symporter activity
D3P10_RS02865	COG1695	Transcriptional regulator
D3P10_RS02880	COG2094	Belongs to the DNA glycosylase MPG family
D3P10_RS02890	COG3620	sequence-specific DNA binding
D3P10_RS02900	COG1069	ribulokinase activity
D3P10_RS02905	COG4152	abc transporter atp-binding protein
D3P10_RS02910	COG1668	transmembrane transport
D3P10_RS02915	COG1742	UPF0060 membrane protein
D3P10_RS02920	COG2017	converts alpha-aldose to the beta-anomer
D3P10_RS02925	COG2258	MOSC domain
D3P10_RS02930	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
D3P10_RS02940	COG1266	CAAX protease self-immunity
D3P10_RS02945	COG0010	Belongs to the arginase family
D3P10_RS02950	COG0583	DNA-binding transcription factor activity
D3P10_RS02965	COG0659	secondary active sulfate transmembrane transporter activity
D3P10_RS02970	COG1473	amidohydrolase
D3P10_RS02975	COG1028	Short-chain dehydrogenase reductase Sdr
D3P10_RS02995	COG1737	Transcriptional regulator
D3P10_RS03000	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D3P10_RS03000	COG1263	PTS System
D3P10_RS03010	COG0385	Bile acid
D3P10_RS03015	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
D3P10_RS03035	COG1113	amino acid transport
D3P10_RS03045	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D3P10_RS03045	COG1263	PTS System
D3P10_RS03050	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
D3P10_RS03065	COG1266	CAAX protease self-immunity
D3P10_RS03070	COG2378	regulation of single-species biofilm formation
D3P10_RS03080	COG1316	TRANSCRIPTIONal
D3P10_RS03110	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
D3P10_RS03115	COG2076	Multidrug Resistance protein
D3P10_RS03120	COG2076	Multidrug Resistance protein
D3P10_RS03125	COG3942	CHAP domain
D3P10_RS03140	COG1757	Na H antiporter
D3P10_RS03145	COG3942	CHAP domain
D3P10_RS03155	COG1846	Transcriptional regulator
D3P10_RS03170	COG0829	nickel cation binding
D3P10_RS03185	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
D3P10_RS03190	COG0804	urea catabolic process
D3P10_RS03200	COG0831	urea catabolic process
D3P10_RS03205	COG4413	Urea transporter
D3P10_RS03210	COG0765	amino acid transport
D3P10_RS03215	COG0765	amino acid transport
D3P10_RS03220	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D3P10_RS03225	COG1126	abc transporter atp-binding protein
D3P10_RS03230	COG1960	acyl-CoA dehydrogenase activity
D3P10_RS03245	COG1268	BioY protein
D3P10_RS03255	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
D3P10_RS03260	COG0725	ABC transporter, periplasmic molybdate-binding protein
D3P10_RS03265	COG4149	molybdate abc transporter
D3P10_RS03270	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
D3P10_RS03275	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
D3P10_RS03280	COG0521	Mo-molybdopterin cofactor biosynthetic process
D3P10_RS03285	COG0315	cyclic pyranopterin monophosphate synthase activity
D3P10_RS03295	COG1763	Mo-molybdopterin cofactor biosynthetic process
D3P10_RS03315	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
D3P10_RS03325	COG2814	Major facilitator Superfamily
D3P10_RS03345	COG2348	transferase activity, transferring amino-acyl groups
D3P10_RS03350	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
D3P10_RS03370	COG4975	Glucose uptake
D3P10_RS03385	COG2252	PERMEase
D3P10_RS03400	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
D3P10_RS03405	COG0088	Forms part of the polypeptide exit tunnel
D3P10_RS03410	COG0089	rRNA binding
D3P10_RS03415	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
D3P10_RS03420	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
D3P10_RS03425	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
D3P10_RS03430	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
D3P10_RS03435	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
D3P10_RS03445	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
D3P10_RS03450	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
D3P10_RS03455	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
D3P10_RS03465	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
D3P10_RS03470	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
D3P10_RS03475	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
D3P10_RS03480	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
D3P10_RS03485	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
D3P10_RS03490	COG1841	ribosomal large subunit assembly
D3P10_RS03500	COG0201	protein transport
D3P10_RS03505	COG0563	adenylate kinase activity
D3P10_RS03510	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
D3P10_RS03520	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
D3P10_RS03525	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
D3P10_RS03530	COG0202	RNA polymerase activity
D3P10_RS03545	COG1122	ATPase activity
D3P10_RS03560	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
D3P10_RS03580	COG0698	ribose 5-phosphate isomerase
D3P10_RS03620	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
D3P10_RS03625	COG2130	NADP-dependent
D3P10_RS03630	COG0604	alcohol dehydrogenase
D3P10_RS03635	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
D3P10_RS03650	COG1302	Protein conserved in bacteria
D3P10_RS03660	COG2814	Major facilitator Superfamily
D3P10_RS03665	COG4264	IucA IucC family
D3P10_RS03670	COG3457	Alanine racemase
D3P10_RS03675	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
D3P10_RS03680	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D3P10_RS03685	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D3P10_RS03690	COG3314	Sporulation integral membrane protein YlbJ
D3P10_RS03695	COG2329	Antibiotic biosynthesis monooxygenase
D3P10_RS03705	COG1988	membrane-bound metal-dependent
D3P10_RS03710	COG4284	Utp--glucose-1-phosphate uridylyltransferase
D3P10_RS03715	COG1272	protein, Hemolysin III
D3P10_RS03730	COG2814	Major facilitator Superfamily
D3P10_RS03735	COG0489	protein tyrosine kinase activity
D3P10_RS03790	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
D3P10_RS03815	COG3711	transcriptional antiterminator
D3P10_RS03830	COG0561	phosphatase activity
D3P10_RS03850	COG0640	Transcriptional regulator
D3P10_RS03855	COG0702	epimerase
D3P10_RS03860	COG1482	cell wall glycoprotein biosynthetic process
D3P10_RS03880	COG0783	Belongs to the Dps family
D3P10_RS03885	COG0813	purine-nucleoside phosphorylase activity
D3P10_RS03890	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
D3P10_RS03895	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
D3P10_RS03900	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
D3P10_RS03910	COG1854	S-ribosylhomocysteine lyase activity
D3P10_RS03930	COG5146	pantothenate kinase activity
D3P10_RS03945	COG0504	CTP synthase activity
D3P10_RS03955	COG0191	fructose-bisphosphate aldolase activity
D3P10_RS03960	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
D3P10_RS03970	COG1012	belongs to the aldehyde dehydrogenase family
D3P10_RS03975	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
D3P10_RS03980	COG0254	rRNA binding
D3P10_RS03985	COG1435	thymidine kinase activity
D3P10_RS03995	COG2890	protein-(glutamine-N5) methyltransferase activity
D3P10_RS04000	COG0009	L-threonylcarbamoyladenylate synthase
D3P10_RS04005	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
D3P10_RS04010	COG4475	Protein of unknown function (DUF436)
D3P10_RS04020	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
D3P10_RS04025	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
D3P10_RS04050	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
D3P10_RS04060	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
D3P10_RS04065	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
D3P10_RS04070	COG0355	proton-transporting ATP synthase activity, rotational mechanism
D3P10_RS04085	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
D3P10_RS04110	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
D3P10_RS04120	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
D3P10_RS04125	COG0352	thiamine-phosphate diphosphorylase activity
D3P10_RS04130	COG0706	membrane insertase activity
D3P10_RS04135	COG1418	mRNA catabolic process
D3P10_RS04140	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
D3P10_RS04145	COG1937	Protein conserved in bacteria
D3P10_RS04160	COG0772	Belongs to the SEDS family
D3P10_RS04165	COG1181	Belongs to the D-alanine--D-alanine ligase family
D3P10_RS04170	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
D3P10_RS04175	COG0513	Belongs to the DEAD box helicase family
D3P10_RS04185	COG3428	Bacterial PH domain
D3P10_RS04195	COG0736	holo-[acyl-carrier-protein] synthase activity
D3P10_RS04200	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
D3P10_RS04210	COG2337	Toxic component of a toxin-antitoxin (TA) module
D3P10_RS04220	COG2208	phosphoserine phosphatase activity
D3P10_RS04235	COG1191	sigma factor activity
D3P10_RS04240	COG2183	response to ionizing radiation
D3P10_RS04285	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
D3P10_RS04290	COG0473	3-isopropylmalate dehydrogenase activity
D3P10_RS04310	COG0028	Belongs to the TPP enzyme family
D3P10_RS04315	COG0129	dihydroxy-acid dehydratase activity
D3P10_RS04320	COG0802	atpase or kinase
D3P10_RS04325	COG1214	PFAM Peptidase M22, glycoprotease
D3P10_RS04330	COG0456	acetyltransferase
D3P10_RS04335	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
D3P10_RS04340	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
D3P10_RS04345	COG0488	(ABC) transporter
D3P10_RS04360	COG2391	methyltransferase activity
D3P10_RS04365	COG0425	Belongs to the sulfur carrier protein TusA family
D3P10_RS04370	COG1609	Transcriptional regulator
D3P10_RS04375	COG1621	beta-fructofuranosidase activity
D3P10_RS04380	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
D3P10_RS04435	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
D3P10_RS04440	COG0459	protein refolding
D3P10_RS04465	COG1725	Transcriptional regulator
D3P10_RS04480	COG1131	(ABC) transporter
D3P10_RS04525	COG2706	6-phosphogluconolactonase activity
D3P10_RS04530	COG1012	belongs to the aldehyde dehydrogenase family
D3P10_RS04535	COG1227	inorganic diphosphatase activity
D3P10_RS04540	COG1335	isochorismatase
D3P10_RS04550	COG0077	Prephenate dehydratase
D3P10_RS04560	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
D3P10_RS04565	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
D3P10_RS04570	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
D3P10_RS04580	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
D3P10_RS04585	COG4496	protein, YerC YecD
D3P10_RS04590	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
D3P10_RS04595	COG0210	DNA helicase
D3P10_RS04600	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
D3P10_RS04610	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
D3P10_RS04625	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
D3P10_RS04630	COG1597	lipid kinase activity
D3P10_RS04635	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
D3P10_RS04655	COG1528	Iron-storage protein
D3P10_RS04670	COG4129	membrane
D3P10_RS04675	COG0024	Methionine aminopeptidase
D3P10_RS04695	COG2197	response regulator
D3P10_RS04700	COG1295	ribonuclease BN
D3P10_RS04715	COG4840	Belongs to the UPF0435 family
D3P10_RS04720	COG2309	aminopeptidase activity
D3P10_RS04730	COG0535	radical SAM domain protein
D3P10_RS04740	COG0693	protein deglycase activity
D3P10_RS04745	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
D3P10_RS04760	COG1388	LysM domain
D3P10_RS04760	COG1134	teichoic acid transport
D3P10_RS04770	COG1988	membrane-bound metal-dependent
D3P10_RS04775	COG1194	a g-specific adenine glycosylase
D3P10_RS04780	COG3557	Belongs to the UPF0374 family
D3P10_RS04790	COG4129	membrane
D3P10_RS04795	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
D3P10_RS04800	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
D3P10_RS04805	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
D3P10_RS04810	COG0735	belongs to the Fur family
D3P10_RS04975	COG0765	amino acid transport
D3P10_RS04980	COG1126	abc transporter atp-binding protein
D3P10_RS04985	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
D3P10_RS04995	COG0363	glucosamine-6-phosphate deaminase activity
D3P10_RS05010	COG0114	fumarate hydratase activity
D3P10_RS05015	COG0564	pseudouridine synthase activity
D3P10_RS05020	COG2203	Gaf domain
D3P10_RS05020	COG4585	Histidine kinase
D3P10_RS05025	COG2197	response regulator
D3P10_RS05035	COG4399	Belongs to the UPF0754 family
D3P10_RS05040	COG3679	Belongs to the UPF0342 family
D3P10_RS05045	COG0420	3'-5' exonuclease activity
D3P10_RS05055	COG3481	metal-dependent phosphohydrolase, HD sub domain
D3P10_RS05065	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
D3P10_RS05080	COG0537	adenosine 5'-monophosphoramidase activity
D3P10_RS05085	COG1131	(ABC) transporter
D3P10_RS05090	COG4473	ABC transporter
D3P10_RS05095	COG2329	Antibiotic biosynthesis monooxygenase
D3P10_RS05105	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
D3P10_RS05110	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
D3P10_RS05115	COG3545	Serine hydrolase
D3P10_RS05165	COG0318	PFAM AMP-dependent synthetase and ligase
D3P10_RS05180	COG0494	nUDIX hydrolase
D3P10_RS05185	COG1506	peptidase
D3P10_RS05195	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
D3P10_RS05205	COG0656	L-ascorbic acid biosynthetic process
D3P10_RS05210	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
D3P10_RS05215	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
D3P10_RS05225	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
D3P10_RS05250	COG4193	domain, Protein
D3P10_RS05250	COG5632	N-Acetylmuramoyl-L-alanine amidase
D3P10_RS05250	COG3266	domain, Protein
D3P10_RS05260	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
D3P10_RS05260	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
D3P10_RS05265	COG0307	riboflavin synthase, alpha
D3P10_RS05270	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
D3P10_RS05270	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
D3P10_RS05275	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
D3P10_RS05285	COG2267	carboxylic ester hydrolase activity
D3P10_RS05295	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
D3P10_RS05300	COG1242	4 iron, 4 sulfur cluster binding
D3P10_RS05305	COG2814	Major facilitator Superfamily
D3P10_RS05310	COG0495	leucyl-tRNA aminoacylation
D3P10_RS05315	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
D3P10_RS05330	COG2081	HI0933 family
D3P10_RS05335	COG2244	polysaccharide biosynthetic process
D3P10_RS05340	COG1187	pseudouridine synthase activity
D3P10_RS05350	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
D3P10_RS05355	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
D3P10_RS05360	COG0510	thiamine kinase activity
D3P10_RS05365	COG0220	tRNA (guanine-N7-)-methyltransferase activity
D3P10_RS05370	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
D3P10_RS05380	COG1363	Peptidase, m42
D3P10_RS05385	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D3P10_RS05390	COG4848	Belongs to the UPF0354 family
D3P10_RS05395	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
D3P10_RS05400	COG1674	ftsk spoiiie
D3P10_RS05405	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
D3P10_RS05420	COG1605	Chorismate mutase
D3P10_RS05420	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
D3P10_RS05425	COG1609	Transcriptional regulator
D3P10_RS05435	COG0454	-acetyltransferase
D3P10_RS05440	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
D3P10_RS05450	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
D3P10_RS05470	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
D3P10_RS05475	COG0204	Acyl-transferase
D3P10_RS05495	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D3P10_RS05495	COG1263	PTS System
D3P10_RS05505	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
D3P10_RS05510	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
D3P10_RS05515	COG1764	response to oxidative stress
D3P10_RS05520	COG0584	glycerophosphoryl diester phosphodiesterase
D3P10_RS05525	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
D3P10_RS05535	COG1956	GAF domain-containing protein
D3P10_RS05540	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
D3P10_RS05545	COG1104	cysteine desulfurase activity
D3P10_RS05550	COG0301	tRNA thio-modification
D3P10_RS05560	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
D3P10_RS05565	COG0827	DNA restriction-modification system
D3P10_RS05570	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
D3P10_RS05575	COG0589	response to stress
D3P10_RS05580	COG0686	Belongs to the AlaDH PNT family
D3P10_RS05585	COG0006	proline dipeptidase activity
D3P10_RS05590	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
D3P10_RS05600	COG4109	DRTGG domain
D3P10_RS05605	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
D3P10_RS05610	COG0587	DNA-directed DNA polymerase activity
D3P10_RS05615	COG0281	malic enzyme
D3P10_RS05620	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
D3P10_RS05630	COG0205	6-phosphofructokinase activity
D3P10_RS05635	COG0469	pyruvate kinase activity
D3P10_RS05640	COG1113	amino acid transport
D3P10_RS05645	COG0372	Belongs to the citrate synthase family
D3P10_RS05650	COG0538	isocitrate dehydrogenase activity
D3P10_RS05655	COG0745	RESPONSE REGULATOR receiver
D3P10_RS05660	COG5002	protein histidine kinase activity
D3P10_RS05665	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
D3P10_RS05665	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
D3P10_RS05670	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
D3P10_RS05680	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
D3P10_RS05685	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
D3P10_RS05690	COG3611	Membrane attachment protein
D3P10_RS05695	COG1484	DNA-dependent DNA replication
D3P10_RS05705	COG0833	amino acid
D3P10_RS05710	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
D3P10_RS05715	COG0291	Belongs to the bacterial ribosomal protein bL35 family
D3P10_RS05720	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
D3P10_RS05725	COG4112	unkown
D3P10_RS05735	COG0544	peptidyl-prolyl cis-trans isomerase activity
D3P10_RS05740	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
D3P10_RS05745	COG0218	Necessary for normal cell division and for the maintenance of normal septation
D3P10_RS05750	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
D3P10_RS05760	COG0181	hydroxymethylbilane synthase activity
D3P10_RS05770	COG0113	porphobilinogen synthase activity
D3P10_RS05775	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
D3P10_RS05785	COG2818	Glycosylase
D3P10_RS05790	COG0525	valine-tRNA ligase activity
D3P10_RS05795	COG0285	dihydrofolate synthase activity
D3P10_RS05805	COG2003	Belongs to the UPF0758 family
D3P10_RS05840	COG0261	This protein binds to 23S rRNA in the presence of protein L20
D3P10_RS05845	COG2868	ribosomal protein
D3P10_RS05850	COG0211	Belongs to the bacterial ribosomal protein bL27 family
D3P10_RS05855	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
D3P10_RS05860	COG4492	Belongs to the UPF0735 family
D3P10_RS05865	COG0632	four-way junction helicase activity
D3P10_RS05875	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
D3P10_RS05885	COG1862	Preprotein translocase
D3P10_RS05890	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
D3P10_RS05890	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
D3P10_RS05895	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
D3P10_RS05895	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
D3P10_RS05905	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
D3P10_RS05915	COG0860	N-Acetylmuramoyl-L-alanine amidase
D3P10_RS05925	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
D3P10_RS05935	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
D3P10_RS05940	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
D3P10_RS05945	COG1959	2 iron, 2 sulfur cluster binding
D3P10_RS05955	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
D3P10_RS05960	COG1104	cysteine desulfurase activity
D3P10_RS05965	COG0482	sulfurtransferase activity
D3P10_RS05975	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
D3P10_RS05985	COG4472	Bacterial protein of unknown function (DUF965)
D3P10_RS05990	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
D3P10_RS05995	COG3906	Belongs to the UPF0473 family
D3P10_RS06000	COG4122	O-methyltransferase activity
D3P10_RS06005	COG0826	peptidase U32
D3P10_RS06010	COG0826	peptidase U32
D3P10_RS06015	COG0572	uridine kinase
D3P10_RS06020	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
D3P10_RS06025	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
D3P10_RS06030	COG1984	allophanate hydrolase subunit 2
D3P10_RS06035	COG0511	ligase activity, forming carbon-carbon bonds
D3P10_RS06040	COG0439	Biotin carboxylase
D3P10_RS06050	COG1914	H( )-stimulated, divalent metal cation uptake system
D3P10_RS06055	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
D3P10_RS06060	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
D3P10_RS06065	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
D3P10_RS06070	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
D3P10_RS06075	COG1534	Rna-binding protein
D3P10_RS06080	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
D3P10_RS06085	COG1713	HD superfamily hydrolase involved in NAD metabolism
D3P10_RS06090	COG0799	negative regulation of ribosome biogenesis
D3P10_RS06100	COG1596	polysaccharide export
D3P10_RS06100	COG1555	photosystem II stabilization
D3P10_RS06105	COG2131	deaminase
D3P10_RS06110	COG2333	competence protein COMEC
D3P10_RS06110	COG0658	competence protein
D3P10_RS06115	COG1466	dna polymerase III delta subunit
D3P10_RS06120	COG0268	Binds directly to 16S ribosomal RNA
D3P10_RS06125	COG0481	GTPase activity
D3P10_RS06130	COG0635	Involved in the biosynthesis of porphyrin-containing compound
D3P10_RS06140	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
D3P10_RS06145	COG0443	Heat shock 70 kDa protein
D3P10_RS06150	COG0484	heat shock protein binding
D3P10_RS06160	COG1385	rRNA (uridine-N3-)-methyltransferase activity
D3P10_RS06165	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
D3P10_RS06175	COG1030	water channel activity
D3P10_RS06180	COG4864	UPF0365 protein
D3P10_RS06190	COG1702	phosphate starvation-inducible protein PhoH
D3P10_RS06210	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
D3P10_RS06215	COG1381	Involved in DNA repair and RecF pathway recombination
D3P10_RS06220	COG0423	glycine-tRNA ligase activity
D3P10_RS06225	COG0517	IMP dehydrogenase activity
D3P10_RS06230	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
D3P10_RS06240	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
D3P10_RS06245	COG2384	SAM-dependent methyltransferase
D3P10_RS06250	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
D3P10_RS06255	COG0513	Belongs to the DEAD box helicase family
D3P10_RS06260	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
D3P10_RS06265	COG1121	(ABC) transporter
D3P10_RS06270	COG1108	ABC-type Mn2 Zn2 transport systems permease components
D3P10_RS06285	COG0768	penicillin binding
D3P10_RS06290	COG0267	Belongs to the bacterial ribosomal protein bL33 family
D3P10_RS06295	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
D3P10_RS06305	COG4483	Protein conserved in bacteria
D3P10_RS06310	COG1940	carbohydrate kinase activity
D3P10_RS06315	COG0011	TIGRFAM Protein of
D3P10_RS06320	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
D3P10_RS06325	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
D3P10_RS06330	COG1459	type II secretion system
D3P10_RS06335	COG4537	Required for transformation and DNA binding
D3P10_RS06355	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
D3P10_RS06360	COG0404	The glycine cleavage system catalyzes the degradation of glycine
D3P10_RS06375	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
D3P10_RS06380	COG0095	Lipoate-protein ligase
D3P10_RS06395	COG0006	proline dipeptidase activity
D3P10_RS06400	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
D3P10_RS06405	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
D3P10_RS06410	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
D3P10_RS06415	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
D3P10_RS06420	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
D3P10_RS06425	COG0511	ligase activity, forming carbon-carbon bonds
D3P10_RS06430	COG0439	Biotin carboxylase
D3P10_RS06435	COG1302	Protein conserved in bacteria
D3P10_RS06440	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
D3P10_RS06450	COG1722	exodeoxyribonuclease VII activity
D3P10_RS06455	COG0142	geranyltranstransferase activity
D3P10_RS06460	COG1438	arginine binding
D3P10_RS06465	COG0497	DNA recombination
D3P10_RS06470	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
D3P10_RS06475	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
D3P10_RS06480	COG0022	dehydrogenase e1 component
D3P10_RS06485	COG0508	dehydrogenase complex catalyzes the overall conversion of
D3P10_RS06495	COG4129	membrane
D3P10_RS06500	COG2195	Cleaves the N-terminal amino acid of tripeptides
D3P10_RS06505	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
D3P10_RS06510	COG0366	Alpha amylase catalytic
D3P10_RS06520	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
D3P10_RS06525	COG1234	tRNA 3'-trailer cleavage
D3P10_RS06530	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
D3P10_RS06535	COG1028	Short-chain dehydrogenase reductase Sdr
D3P10_RS06540	COG0667	Aldo Keto reductase
D3P10_RS06545	COG0494	nUDIX hydrolase
D3P10_RS06550	COG0735	belongs to the Fur family
D3P10_RS06555	COG4974	Belongs to the 'phage' integrase family
D3P10_RS06565	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
D3P10_RS06570	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
D3P10_RS06575	COG1187	pseudouridine synthase activity
D3P10_RS06580	COG0745	RESPONSE REGULATOR receiver
D3P10_RS06595	COG1141	Ferredoxin
D3P10_RS06605	COG0514	ATP-dependent DNA helicase (RecQ)
D3P10_RS06615	COG0492	ferredoxin-NADP+ reductase activity
D3P10_RS06625	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
D3P10_RS06630	COG0539	negative regulation of cytoplasmic translation
D3P10_RS06635	COG1160	GTP binding
D3P10_RS06640	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
D3P10_RS06655	COG2226	methyltransferase
D3P10_RS06670	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
D3P10_RS06675	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
D3P10_RS06690	COG5582	Belongs to the UPF0302 family
D3P10_RS06695	COG4347	Protein of unknown function (DUF1405)
D3P10_RS06700	COG2738	Putative neutral zinc metallopeptidase
D3P10_RS06705	COG1694	Mazg nucleotide pyrophosphohydrolase
D3P10_RS06710	COG0438	transferase activity, transferring glycosyl groups
D3P10_RS06715	COG0617	tRNA 3'-terminal CCA addition
D3P10_RS06720	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
D3P10_RS06720	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
D3P10_RS06725	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
D3P10_RS06725	COG1199	ATP-dependent helicase activity
D3P10_RS06730	COG0017	Asparaginyl-tRNA synthetase
D3P10_RS06735	COG3935	DnaD domain protein
D3P10_RS06740	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
D3P10_RS06750	COG4499	WXG100 protein secretion system (Wss), protein YukC
D3P10_RS06750	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
D3P10_RS06755	COG3331	DNA recombination
D3P10_RS06770	COG3599	regulation of cell shape
D3P10_RS06780	COG0116	Belongs to the methyltransferase superfamily
D3P10_RS06790	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
D3P10_RS06795	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
D3P10_RS06810	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
D3P10_RS06820	COG1413	lyase activity
D3P10_RS06855	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
D3P10_RS06860	COG2190	(PTS) system
D3P10_RS06870	COG0793	Belongs to the peptidase S41A family
D3P10_RS06880	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
D3P10_RS06885	COG0671	phosphoesterase, PA-phosphatase related
D3P10_RS06890	COG0745	RESPONSE REGULATOR receiver
D3P10_RS06895	COG5002	protein histidine kinase activity
D3P10_RS06900	COG0567	Dehydrogenase, E1 component
D3P10_RS06905	COG0508	dehydrogenase complex catalyzes the overall conversion of
D3P10_RS06910	COG1131	(ABC) transporter
D3P10_RS06935	COG0714	Associated with various cellular activities
D3P10_RS06940	COG4548	von Willebrand factor, type A
D3P10_RS06945	COG1114	Component of the transport system for branched-chain amino acids
D3P10_RS06950	COG3853	Toxic anion resistance protein (TelA)
D3P10_RS06960	COG1254	Belongs to the acylphosphatase family
D3P10_RS06970	COG1278	Cold shock
D3P10_RS06985	COG1473	amidohydrolase
D3P10_RS06995	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
D3P10_RS07000	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
D3P10_RS07005	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
D3P10_RS07010	COG0527	aspartate kinase activity
D3P10_RS07020	COG0488	(ABC) transporter
D3P10_RS07025	COG2996	Protein conserved in bacteria
D3P10_RS07030	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
D3P10_RS07035	COG0573	inorganic phosphate transmembrane transporter activity
D3P10_RS07040	COG0581	inorganic phosphate transmembrane transporter activity
D3P10_RS07045	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
D3P10_RS07085	COG4607	ABC-type enterochelin transport system periplasmic component
D3P10_RS07090	COG0561	phosphatase activity
D3P10_RS07095	COG2348	transferase activity, transferring amino-acyl groups
D3P10_RS07100	COG2348	transferase activity, transferring amino-acyl groups
D3P10_RS07120	COG0134	indole-3-glycerol-phosphate synthase activity
D3P10_RS07130	COG0512	Glutamine amidotransferase of anthranilate synthase
D3P10_RS07135	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
D3P10_RS07140	COG1363	Peptidase, m42
D3P10_RS07145	COG0287	Prephenate dehydrogenase
D3P10_RS07150	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
D3P10_RS07155	COG1942	4-Oxalocrotonate Tautomerase
D3P10_RS07170	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
D3P10_RS07170	COG0392	lysyltransferase activity
D3P10_RS07175	COG0628	permease
D3P10_RS07180	COG3711	transcriptional antiterminator
D3P10_RS07185	COG1115	amino acid carrier protein
D3P10_RS07190	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
D3P10_RS07195	COG0187	DNA topoisomerase II activity
D3P10_RS07210	COG0824	Thioesterase
D3P10_RS07215	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
D3P10_RS07220	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
D3P10_RS07225	COG1970	mechanosensitive ion channel activity
D3P10_RS07240	COG4846	Membrane protein involved in cytochrome C biogenesis
D3P10_RS07250	COG3763	UPF0154 protein
D3P10_RS07260	COG4224	UPF0291 protein
D3P10_RS07285	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
D3P10_RS07300	COG0833	amino acid
D3P10_RS07315	COG0083	homoserine kinase activity
D3P10_RS07320	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
D3P10_RS07325	COG0460	homoserine dehydrogenase
D3P10_RS07330	COG0527	aspartate kinase activity
D3P10_RS07345	COG1525	nuclease
D3P10_RS07395	COG0789	Transcriptional regulator
D3P10_RS07400	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
D3P10_RS07405	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
D3P10_RS07410	COG0386	Belongs to the glutathione peroxidase family
D3P10_RS07415	COG1923	regulation of RNA biosynthetic process
D3P10_RS07420	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
D3P10_RS07430	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
D3P10_RS07440	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
D3P10_RS07445	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
D3P10_RS07450	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
D3P10_RS07465	COG4550	Control of competence regulator ComK, YlbF/YmcA
D3P10_RS07470	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
D3P10_RS07480	COG4195	phage-related replication protein
D3P10_RS07485	COG1013	pyruvate-flavodoxin oxidoreductase activity
D3P10_RS07490	COG0674	pyruvate-flavodoxin oxidoreductase activity
D3P10_RS07490	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
D3P10_RS07495	COG1692	metallophosphoesterase
D3P10_RS07505	COG1418	mRNA catabolic process
D3P10_RS07510	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
D3P10_RS07515	COG1058	Belongs to the CinA family
D3P10_RS07515	COG1546	Belongs to the CinA family
D3P10_RS07525	COG1426	Protein conserved in bacteria
D3P10_RS07535	COG1028	Short-chain dehydrogenase reductase Sdr
D3P10_RS07540	COG0612	Peptidase, M16
D3P10_RS07545	COG0612	Peptidase, M16
D3P10_RS07550	COG2188	Transcriptional regulator
D3P10_RS07560	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
D3P10_RS07570	COG1185	polyribonucleotide nucleotidyltransferase activity
D3P10_RS07575	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
D3P10_RS07580	COG0196	riboflavin kinase activity
D3P10_RS07585	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
D3P10_RS07590	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
D3P10_RS07595	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
D3P10_RS07600	COG1358	cellular component organization or biogenesis
D3P10_RS07605	COG2740	Nucleic-acid-binding protein implicated in transcription termination
D3P10_RS07610	COG0195	Participates in both transcription termination and antitermination
D3P10_RS07615	COG0779	Required for maturation of 30S ribosomal subunits
D3P10_RS07620	COG2176	DNA-directed DNA polymerase activity
D3P10_RS07625	COG0442	prolyl-tRNA aminoacylation
D3P10_RS07635	COG4589	Belongs to the CDS family
D3P10_RS07640	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
D3P10_RS07645	COG0233	cytoplasmic translational termination
D3P10_RS07650	COG0528	UMP kinase activity
D3P10_RS07655	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
D3P10_RS07660	COG0052	Belongs to the universal ribosomal protein uS2 family
D3P10_RS07675	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
D3P10_RS07680	COG4974	Belongs to the 'phage' integrase family
D3P10_RS07685	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
D3P10_RS07690	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
D3P10_RS07695	COG0758	DNA mediated transformation
D3P10_RS07700	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
D3P10_RS07705	COG0045	succinate-CoA ligase (ADP-forming) activity
D3P10_RS07710	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
D3P10_RS07720	COG4485	Bacterial membrane protein, YfhO
D3P10_RS07735	COG0336	Belongs to the RNA methyltransferase TrmD family
D3P10_RS07740	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
D3P10_RS07745	COG0228	four-way junction DNA binding
D3P10_RS07750	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
D3P10_RS07755	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
D3P10_RS07760	COG0552	protein localization to endoplasmic reticulum
D3P10_RS07765	COG1196	nuclear chromosome segregation
D3P10_RS07770	COG0571	ribonuclease III activity
D3P10_RS07775	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
D3P10_RS07790	COG0416	fatty acid biosynthetic process
D3P10_RS07795	COG1349	DNA-binding transcription factor activity
D3P10_RS07800	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
D3P10_RS07805	COG1461	Dihydroxyacetone kinase
D3P10_RS07810	COG1302	Protein conserved in bacteria
D3P10_RS07815	COG0227	Belongs to the bacterial ribosomal protein bL28 family
D3P10_RS07825	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
D3P10_RS07840	COG0631	protein serine/threonine phosphatase activity
D3P10_RS07845	COG0820	rRNA (adenine-C2-)-methyltransferase activity
D3P10_RS07850	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
D3P10_RS07850	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
D3P10_RS07855	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
D3P10_RS07860	COG0242	peptide deformylase activity
D3P10_RS07870	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
D3P10_RS07875	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
D3P10_RS07880	COG1758	RNA polymerase activity
D3P10_RS07885	COG0194	GDP metabolic process
D3P10_RS07905	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
D3P10_RS07910	COG0284	orotidine-5'-phosphate decarboxylase activity
D3P10_RS07915	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
D3P10_RS07920	COG0505	Belongs to the CarA family
D3P10_RS07925	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
D3P10_RS07930	COG0540	Belongs to the ATCase OTCase family
D3P10_RS07935	COG2233	PERMEase
D3P10_RS07940	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
D3P10_RS07950	COG0564	pseudouridine synthase activity
D3P10_RS07960	COG1388	LysM domain
D3P10_RS07960	COG3942	CHAP domain
D3P10_RS07970	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
D3P10_RS07975	COG3599	regulation of cell shape
D3P10_RS07985	COG0762	integral membrane protein
D3P10_RS07990	COG1799	cell septum assembly
D3P10_RS07995	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
D3P10_RS08000	COG1496	oxidoreductase activity
D3P10_RS08005	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
D3P10_RS08010	COG0849	cell division
D3P10_RS08015	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
D3P10_RS08025	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
D3P10_RS08030	COG0768	penicillin binding
D3P10_RS08035	COG4839	cell division protein FtsL
D3P10_RS08040	COG0275	rRNA processing
D3P10_RS08050	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
D3P10_RS08100	COG1388	LysM domain
D3P10_RS08100	COG0860	N-Acetylmuramoyl-L-alanine amidase
D3P10_RS08240	COG1783	phage Terminase large subunit
D3P10_RS08275	COG1525	nuclease
D3P10_RS08325	COG0305	Participates in initiation and elongation during chromosome replication
D3P10_RS08385	COG3645	SOS response
D3P10_RS08385	COG3646	Phage regulatory protein
D3P10_RS08425	COG0582	viral genome integration into host DNA
D3P10_RS08440	COG0860	N-Acetylmuramoyl-L-alanine amidase
D3P10_RS08440	COG1388	LysM domain
D3P10_RS08580	COG1783	phage Terminase large subunit
D3P10_RS08615	COG1525	nuclease
D3P10_RS08665	COG0305	Participates in initiation and elongation during chromosome replication
D3P10_RS08725	COG3645	SOS response
D3P10_RS08725	COG3646	Phage regulatory protein
D3P10_RS08765	COG0582	viral genome integration into host DNA
D3P10_RS08775	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
D3P10_RS08780	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
D3P10_RS08785	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
D3P10_RS08790	COG1053	succinate dehydrogenase
D3P10_RS08795	COG2009	succinate dehydrogenase
D3P10_RS08800	COG0322	excinuclease ABC activity
D3P10_RS08805	COG3118	belongs to the thioredoxin family
D3P10_RS08810	COG1193	negative regulation of DNA recombination
D3P10_RS08815	COG1796	DNA polymerase
D3P10_RS08815	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
D3P10_RS08825	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
D3P10_RS08830	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
D3P10_RS08835	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
D3P10_RS08835	COG0072	phenylalanine-tRNA ligase activity
D3P10_RS08840	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
D3P10_RS08845	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
D3P10_RS08850	COG0333	Belongs to the bacterial ribosomal protein bL32 family
D3P10_RS08865	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
D3P10_RS08870	COG0742	ribosomal rna small subunit methyltransferase
D3P10_RS08885	COG0584	glycerophosphoryl diester phosphodiesterase
D3P10_RS08890	COG3679	Belongs to the UPF0342 family
D3P10_RS08905	COG0109	protoheme IX farnesyltransferase activity
D3P10_RS08910	COG1612	heme a metabolic process
D3P10_RS08920	COG0772	Belongs to the SEDS family
D3P10_RS08925	COG4838	Belongs to the UPF0358 family
D3P10_RS08930	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
D3P10_RS08935	COG4896	Protein conserved in bacteria
D3P10_RS08940	COG1217	gtp-binding protein TYPA
D3P10_RS08950	COG0483	inositol monophosphate 1-phosphatase activity
D3P10_RS08955	COG4493	Belongs to the UPF0637 family
D3P10_RS08985	COG1176	ABC-type spermidine putrescine transport system, permease component I
D3P10_RS09000	COG4476	Belongs to the UPF0223 family
D3P10_RS09010	COG0508	dehydrogenase complex catalyzes the overall conversion of
D3P10_RS09030	COG0242	peptide deformylase activity
D3P10_RS09035	COG5503	Protein of unknown function (DUF1447)
D3P10_RS09040	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
D3P10_RS09045	COG0569	domain protein
D3P10_RS09050	COG1294	oxidase, subunit
D3P10_RS09055	COG1271	oxidase subunit
D3P10_RS09065	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
D3P10_RS09070	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
D3P10_RS09080	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
D3P10_RS09100	COG4172	Belongs to the ABC transporter superfamily
D3P10_RS09105	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
D3P10_RS09110	COG0151	Belongs to the GarS family
D3P10_RS09115	COG0138	bifunctional purine biosynthesis protein purh
D3P10_RS09125	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
D3P10_RS09140	COG0047	phosphoribosylformylglycinamidine synthase activity
D3P10_RS09145	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
D3P10_RS09150	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
D3P10_RS09160	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
D3P10_RS09165	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
D3P10_RS09170	COG1017	nitric oxide dioxygenase activity
D3P10_RS09170	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
D3P10_RS09180	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
D3P10_RS09195	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
D3P10_RS09210	COG1316	TRANSCRIPTIONal
D3P10_RS09235	COG3594	Acyltransferase
D3P10_RS09240	COG0436	Aminotransferase
D3P10_RS09245	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
D3P10_RS09255	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
D3P10_RS09260	COG1169	isochorismate synthase
D3P10_RS09265	COG1575	Belongs to the MenA family. Type 1 subfamily
D3P10_RS09270	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
D3P10_RS09275	COG2314	TM2 domain
D3P10_RS09310	COG4873	Protein conserved in bacteria
D3P10_RS09325	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
D3P10_RS09330	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
D3P10_RS09335	COG0861	Integral membrane protein TerC family
D3P10_RS09340	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
D3P10_RS09350	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
D3P10_RS09355	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
D3P10_RS09360	COG2814	Major facilitator Superfamily
D3P10_RS09365	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
D3P10_RS09370	COG2382	esterase
D3P10_RS09380	COG0628	permease
D3P10_RS09390	COG0569	domain protein
D3P10_RS09390	COG0475	glutathione-regulated potassium exporter activity
D3P10_RS09395	COG2239	Acts as a magnesium transporter
D3P10_RS09400	COG0564	pseudouridine synthase activity
D3P10_RS09405	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
D3P10_RS09410	COG2357	RelA SpoT domain protein
D3P10_RS09425	COG2346	COG2346, Truncated hemoglobins
D3P10_RS09430	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
D3P10_RS09435	COG1164	Oligoendopeptidase f
D3P10_RS09445	COG4862	establishment of competence for transformation
D3P10_RS09450	COG1393	Belongs to the ArsC family
D3P10_RS09455	COG0180	Tryptophanyl-tRNA synthetase
D3P10_RS09460	COG4166	transmembrane transport
D3P10_RS09465	COG4608	Belongs to the ABC transporter superfamily
D3P10_RS09470	COG0444	Belongs to the ABC transporter superfamily
D3P10_RS09475	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
D3P10_RS09480	COG0601	transmembrane transport
D3P10_RS09495	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
D3P10_RS09505	COG0542	response to heat
D3P10_RS09520	COG0561	phosphatase activity
D3P10_RS09525	COG0446	pyridine nucleotide-disulphide oxidoreductase
D3P10_RS09540	COG1074	ATP-dependent DNA helicase activity
D3P10_RS09560	COG0398	Pfam SNARE associated Golgi protein
D3P10_RS09570	COG0137	argininosuccinate synthase activity
D3P10_RS09575	COG0165	Argininosuccinate lyase
D3P10_RS09580	COG0584	glycerophosphoryl diester phosphodiesterase
D3P10_RS09585	COG0584	glycerophosphoryl diester phosphodiesterase
D3P10_RS09605	COG1902	pentaerythritol trinitrate reductase activity
D3P10_RS09610	COG1098	S1 RNA binding domain
D3P10_RS09625	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
D3P10_RS09625	COG2111	Na H antiporter
D3P10_RS09630	COG2111	Na H antiporter
D3P10_RS09635	COG1006	Multisubunit Na H antiporter MnhC subunit
D3P10_RS09640	COG0651	ATP synthesis coupled electron transport
D3P10_RS09650	COG2212	antiporter activity
D3P10_RS09670	COG2050	protein possibly involved in aromatic compounds catabolism
D3P10_RS09675	COG2056	Na+-H+ antiporter family
D3P10_RS09680	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
D3P10_RS09690	COG0316	Belongs to the HesB IscA family
D3P10_RS09695	COG4844	belongs to the
D3P10_RS09700	COG1252	NADH dehydrogenase
D3P10_RS09705	COG4837	Protein of unknown function (DUF1462)
D3P10_RS09710	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
D3P10_RS09715	COG0583	DNA-binding transcription factor activity
D3P10_RS09725	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
D3P10_RS09735	COG1696	Membrane protein involved in D-alanine export
D3P10_RS09740	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D3P10_RS09760	COG2445	Protein of unknown function DUF86
D3P10_RS09770	COG4470	Protein conserved in bacteria
D3P10_RS09775	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
D3P10_RS09780	COG0737	Belongs to the 5'-nucleotidase family
D3P10_RS09785	COG0730	response to heat
D3P10_RS09790	COG1801	Protein of unknown function DUF72
D3P10_RS09795	COG2070	2-Nitropropane dioxygenase
D3P10_RS09800	COG1253	flavin adenine dinucleotide binding
D3P10_RS09805	COG0719	Fe-S assembly protein
D3P10_RS09810	COG0822	iron-sulfur transferase activity
D3P10_RS09815	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
D3P10_RS09820	COG0719	Fe-S assembly protein
D3P10_RS09825	COG0396	ATPase activity
D3P10_RS09835	COG3237	CsbD-like
D3P10_RS09840	COG1464	Belongs to the NlpA lipoprotein family
D3P10_RS09845	COG2011	ABC-type metal ion transport system permease component
D3P10_RS09850	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
D3P10_RS09860	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
D3P10_RS09865	COG0509	glycine decarboxylation via glycine cleavage system
D3P10_RS09870	COG1393	Belongs to the ArsC family
D3P10_RS09875	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D3P10_RS09885	COG0710	3-dehydroquinate dehydratase activity
D3P10_RS09890	COG1764	response to oxidative stress
D3P10_RS09900	COG0406	alpha-ribazole phosphatase activity
D3P10_RS09935	COG4195	phage-related replication protein
D3P10_RS09960	COG1278	Cold shock
D3P10_RS09985	COG0656	L-ascorbic acid biosynthetic process
D3P10_RS09990	COG1309	transcriptional regulator
D3P10_RS10060	COG0557	exoribonuclease II activity
D3P10_RS10065	COG1647	Serine aminopeptidase, S33
D3P10_RS10070	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
D3P10_RS10080	COG0148	phosphopyruvate hydratase activity
D3P10_RS10085	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
D3P10_RS10090	COG0149	triose-phosphate isomerase activity
D3P10_RS10095	COG0126	phosphoglycerate kinase activity
D3P10_RS10105	COG2390	Transcriptional regulator
D3P10_RS10130	COG0740	serine-type endopeptidase activity
D3P10_RS10140	COG1481	regulation of sporulation
D3P10_RS10145	COG0391	Required for morphogenesis under gluconeogenic growth conditions
D3P10_RS10150	COG1660	Displays ATPase and GTPase activities
D3P10_RS10155	COG0492	ferredoxin-NADP+ reductase activity
D3P10_RS10170	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
D3P10_RS10180	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
D3P10_RS10185	COG0556	nucleotide-excision repair
D3P10_RS10200	COG1388	LysM domain
D3P10_RS10200	COG3942	CHAP domain
D3P10_RS10210	COG0653	protein targeting
D3P10_RS10215	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
D3P10_RS10220	COG1040	competence protein
D3P10_RS10225	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
D3P10_RS10235	COG1739	Uncharacterized protein family UPF0029
D3P10_RS10240	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
D3P10_RS10260	COG2195	Cleaves the N-terminal amino acid of tripeptides
D3P10_RS10265	COG1929	Belongs to the glycerate kinase type-1 family
D3P10_RS10285	COG0812	UDP-N-acetylmuramate dehydrogenase activity
D3P10_RS10300	COG4604	ABC transporter, ATP-binding protein
D3P10_RS10305	COG4605	iron ion homeostasis
D3P10_RS10310	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D3P10_RS10315	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
D3P10_RS10320	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
D3P10_RS10325	COG1780	Probably involved in ribonucleotide reductase function
D3P10_RS10340	COG3104	oligopeptide transport
D3P10_RS10345	COG1597	lipid kinase activity
D3P10_RS10355	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
D3P10_RS10360	COG1174	glycine betaine transport
D3P10_RS10370	COG0514	ATP-dependent DNA helicase (RecQ)
D3P10_RS10375	COG0488	(ABC) transporter
D3P10_RS10385	COG1368	sulfuric ester hydrolase activity
D3P10_RS10415	COG0512	Glutamine amidotransferase of anthranilate synthase
D3P10_RS10415	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
D3P10_RS10420	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
D3P10_RS10425	COG0720	synthase
D3P10_RS10430	COG0602	queuosine metabolic process
D3P10_RS10440	COG0463	Glycosyl transferase, family 2
D3P10_RS10445	COG0656	L-ascorbic acid biosynthetic process
D3P10_RS10450	COG1253	flavin adenine dinucleotide binding
D3P10_RS10455	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
D3P10_RS10460	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
D3P10_RS10460	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
D3P10_RS10460	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
D3P10_RS10465	COG1105	Belongs to the carbohydrate kinase PfkB family
D3P10_RS10470	COG1349	DNA-binding transcription factor activity
D3P10_RS10475	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
D3P10_RS10500	COG0415	Belongs to the DNA photolyase family
D3P10_RS10505	COG0471	metal ion transport
D3P10_RS10510	COG0039	L-malate dehydrogenase activity
D3P10_RS10520	COG4989	oxidoreductase activity
D3P10_RS10525	COG0523	cobalamin synthesis protein
D3P10_RS10535	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
D3P10_RS10540	COG4988	ABC transporter
D3P10_RS10545	COG1968	undecaprenyl-diphosphatase activity
D3P10_RS10555	COG1671	Belongs to the UPF0178 family
D3P10_RS10560	COG1611	Belongs to the LOG family
D3P10_RS10565	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
D3P10_RS10570	COG1959	2 iron, 2 sulfur cluster binding
D3P10_RS10580	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
D3P10_RS10605	COG2839	Protein conserved in bacteria
D3P10_RS10610	COG2814	Major facilitator Superfamily
D3P10_RS10615	COG0583	DNA-binding transcription factor activity
D3P10_RS10630	COG0217	transcriptional regulatory protein
D3P10_RS10640	COG0662	Cupin 2, conserved barrel domain protein
D3P10_RS10640	COG2207	Transcriptional regulator
D3P10_RS10650	COG3942	CHAP domain
D3P10_RS10650	COG1388	LysM domain
D3P10_RS10660	COG0306	phosphate transporter
D3P10_RS10665	COG1392	Phosphate transport regulator
D3P10_RS10675	COG0577	efflux transmembrane transporter activity
D3P10_RS10680	COG1136	(ABC) transporter
D3P10_RS10685	COG2205	protein histidine kinase activity
D3P10_RS10695	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
D3P10_RS10705	COG0657	acetylesterase activity
D3P10_RS10710	COG3949	Membrane
D3P10_RS10720	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
D3P10_RS10730	COG2376	Dihydroxyacetone kinase
D3P10_RS10735	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D3P10_RS10740	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D3P10_RS10745	COG1120	ATPase activity
D3P10_RS10750	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
D3P10_RS10760	COG1132	(ABC) transporter
D3P10_RS10765	COG1686	Belongs to the peptidase S11 family
D3P10_RS10770	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
D3P10_RS10780	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
D3P10_RS10785	COG1682	transport, permease protein
D3P10_RS10790	COG1134	teichoic acid transport
D3P10_RS10795	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
D3P10_RS10810	COG1121	(ABC) transporter
D3P10_RS10815	COG1108	ABC-type Mn2 Zn2 transport systems permease components
D3P10_RS10820	COG0803	Belongs to the bacterial solute-binding protein 9 family
D3P10_RS10830	COG1320	monovalent cation:proton antiporter activity
D3P10_RS10840	COG1863	multisubunit Na H antiporter MnhE subunit
D3P10_RS10845	COG0651	ATP synthesis coupled electron transport
D3P10_RS10850	COG1006	Multisubunit Na H antiporter MnhC subunit
D3P10_RS10855	COG2111	Na H antiporter
D3P10_RS10860	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
D3P10_RS10860	COG2111	Na H antiporter
D3P10_RS10895	COG2267	carboxylic ester hydrolase activity
D3P10_RS10915	COG0546	phosphoglycolate phosphatase activity
D3P10_RS10920	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D3P10_RS10925	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
D3P10_RS10940	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
D3P10_RS10945	COG0018	arginyl-trna synthetase
D3P10_RS10965	COG1078	dGTPase activity
D3P10_RS10975	COG0655	NAD(P)H dehydrogenase (quinone) activity
D3P10_RS10980	COG0667	Aldo Keto reductase
D3P10_RS10985	COG4844	belongs to the
D3P10_RS11000	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
D3P10_RS11005	COG0095	Lipoate-protein ligase
D3P10_RS11010	COG0280	phosphate acetyltransferase
D3P10_RS11015	COG3253	May function as heme-dependent peroxidase
D3P10_RS11035	COG2363	Small membrane protein
D3P10_RS11050	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
D3P10_RS11070	COG0477	Major facilitator Superfamily
D3P10_RS11085	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
D3P10_RS11090	COG0363	glucosamine-6-phosphate deaminase activity
D3P10_RS11100	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
D3P10_RS11105	COG1469	GTP cyclohydrolase I activity
D3P10_RS11110	COG2271	Major facilitator Superfamily
D3P10_RS11135	COG0431	NADPH-dependent FMN reductase
D3P10_RS11140	COG0561	phosphatase activity
D3P10_RS11150	COG1428	Deoxynucleoside kinase
D3P10_RS11155	COG1428	Deoxynucleoside kinase
D3P10_RS11160	COG0546	phosphoglycolate phosphatase activity
D3P10_RS11165	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
D3P10_RS11190	COG1063	alcohol dehydrogenase
D3P10_RS11195	COG2814	Major facilitator Superfamily
D3P10_RS11200	COG1349	DNA-binding transcription factor activity
D3P10_RS11225	COG1473	amidohydrolase
D3P10_RS11230	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
D3P10_RS11235	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
D3P10_RS11240	COG0049	tRNA binding
D3P10_RS11245	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
D3P10_RS11255	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
D3P10_RS11260	COG0085	RNA polymerase activity
D3P10_RS11265	COG2813	Specifically methylates the guanine in position
D3P10_RS11270	COG0222	ribosome binding
D3P10_RS11275	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
D3P10_RS11285	COG0081	regulation of translation
D3P10_RS11290	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
D3P10_RS11295	COG0250	Participates in transcription elongation, termination and antitermination
D3P10_RS11305	COG0267	Belongs to the bacterial ribosomal protein bL33 family
D3P10_RS11315	COG3688	RNA-binding protein containing a PIN domain
D3P10_RS11325	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
D3P10_RS11330	COG0215	cysteine-tRNA ligase activity
D3P10_RS11340	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
D3P10_RS11345	COG4956	integral membrane protein (PIN domain superfamily)
D3P10_RS11350	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
D3P10_RS11355	COG0542	response to heat
D3P10_RS11360	COG3869	Catalyzes the specific phosphorylation of arginine residues in
D3P10_RS11365	COG3880	PFAM UvrB UvrC protein
D3P10_RS11375	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
D3P10_RS11380	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
D3P10_RS11385	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
D3P10_RS11390	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
D3P10_RS11475	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
D3P10_RS11480	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
D3P10_RS11485	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
D3P10_RS11505	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
D3P10_RS11520	COG1098	S1 RNA binding domain
D3P10_RS11530	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
D3P10_RS11535	COG3956	TIGRFAM MazG family protein
D3P10_RS11540	COG2244	polysaccharide biosynthetic process
D3P10_RS11545	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
D3P10_RS11550	COG0193	aminoacyl-tRNA hydrolase activity
D3P10_RS11555	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
D3P10_RS11560	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
D3P10_RS11565	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
D3P10_RS11570	COG2088	sporulation resulting in formation of a cellular spore
D3P10_RS11575	COG0251	oxidation-reduction process
D3P10_RS11580	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
D3P10_RS11585	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
D3P10_RS11590	COG4466	Protein conserved in bacteria
D3P10_RS11595	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
D3P10_RS11600	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
D3P10_RS11605	COG0084	hydrolase, TatD family'
D3P10_RS11610	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
D3P10_RS11610	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
D3P10_RS11615	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
D3P10_RS11620	COG2827	Endonuclease containing a URI domain
D3P10_RS11625	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
D3P10_RS11630	COG4467	Involved in initiation control of chromosome replication
D3P10_RS11635	COG1774	PSP1 C-terminal conserved region
D3P10_RS11640	COG0470	DNA polymerase III
D3P10_RS11645	COG3870	Protein conserved in bacteria
D3P10_RS11655	COG1982	Orn Lys Arg decarboxylase major
D3P10_RS11660	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
D3P10_RS11680	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
D3P10_RS11690	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
D3P10_RS11705	COG2188	Transcriptional regulator
D3P10_RS11710	COG0366	Alpha amylase catalytic
D3P10_RS11715	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D3P10_RS11715	COG1263	PTS System
D3P10_RS11725	COG0493	'glutamate synthase
D3P10_RS11730	COG0067	glutamate synthase
D3P10_RS11730	COG0070	glutamate synthase
D3P10_RS11730	COG0069	glutamate synthase activity
D3P10_RS11750	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
D3P10_RS11755	COG0494	nUDIX hydrolase
D3P10_RS11765	COG0438	transferase activity, transferring glycosyl groups
D3P10_RS11780	COG1278	Cold shock
D3P10_RS11785	COG3759	membrane
D3P10_RS11810	COG1846	Transcriptional regulator
D3P10_RS11815	COG0626	cystathionine gamma-synthase activity
D3P10_RS11820	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
D3P10_RS11835	COG1279	arginine transmembrane transporter activity
D3P10_RS11840	COG0733	neurotransmitter:sodium symporter activity
D3P10_RS11850	COG1647	Serine aminopeptidase, S33
D3P10_RS11855	COG0671	phosphoesterase, PA-phosphatase related
D3P10_RS11870	COG5609	conserved protein (DUF2294)
D3P10_RS11875	COG3002	Belongs to the UPF0753 family
D3P10_RS11880	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
D3P10_RS11895	COG0523	cobalamin synthesis protein
D3P10_RS11905	COG0518	GMP synthase (glutamine-hydrolyzing) activity
D3P10_RS11905	COG0519	Catalyzes the synthesis of GMP from XMP
D3P10_RS11910	COG0516	GMP reductase activity
D3P10_RS11910	COG0517	IMP dehydrogenase activity
D3P10_RS11915	COG2233	PERMEase
D3P10_RS11920	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
D3P10_RS11935	COG5183	chlorophyll binding
D3P10_RS11940	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
D3P10_RS11945	COG1823	symporter activity
D3P10_RS11950	COG0778	Nitroreductase
D3P10_RS11955	COG3279	Response regulator of the LytR AlgR family
D3P10_RS11970	COG0450	alkyl hydroperoxide reductase
D3P10_RS11975	COG3634	alkyl hydroperoxide reductase activity
D3P10_RS12000	COG1280	lysine exporter protein (LysE YggA)
D3P10_RS12020	COG5484	DNA packaging
D3P10_RS12020	COG3728	DNA packaging
D3P10_RS12100	COG0582	viral genome integration into host DNA
D3P10_RS12105	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
D3P10_RS12115	COG0360	Binds together with S18 to 16S ribosomal RNA
D3P10_RS12130	COG0012	GTP binding
D3P10_RS12135	COG4481	Protein conserved in bacteria
D3P10_RS12140	COG0668	transmembrane transport
D3P10_RS12145	COG1475	DNA binding
D3P10_RS12155	COG0626	cystathionine gamma-synthase activity
D3P10_RS12160	COG0626	cystathionine gamma-synthase activity
D3P10_RS12165	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
D3P10_RS12165	COG0646	methionine synthase
D3P10_RS12170	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
D3P10_RS12190	COG3942	CHAP domain
D3P10_RS12200	COG3250	beta-galactosidase activity
D3P10_RS12205	COG1028	Short-chain dehydrogenase reductase Sdr
D3P10_RS12210	COG1312	Catalyzes the dehydration of D-mannonate
D3P10_RS12215	COG1904	glucuronate isomerase
D3P10_RS12220	COG2211	Major facilitator Superfamily
D3P10_RS12225	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
D3P10_RS12230	COG0800	Aldolase
D3P10_RS12235	COG2207	Transcriptional regulator
D3P10_RS12280	COG1476	TRANSCRIPTIONal
D3P10_RS12290	COG1131	(ABC) transporter
D3P10_RS12310	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
D3P10_RS12330	COG1136	(ABC) transporter
D3P10_RS12335	COG0577	efflux transmembrane transporter activity
D3P10_RS12395	COG1682	transport, permease protein
D3P10_RS12415	COG2348	transferase activity, transferring amino-acyl groups
D3P10_RS12430	COG0577	efflux transmembrane transporter activity
D3P10_RS12435	COG1136	(ABC) transporter
D3P10_RS12470	COG1475	DNA binding
D3P10_RS12475	COG0357	Ribosomal RNA small subunit methyltransferase G
D3P10_RS12480	COG0445	tRNA wobble uridine modification
D3P10_RS12485	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
D3P10_RS12490	COG0594	ribonuclease P activity