locus-tag	class	description
EOJ31_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
EOJ31_RS00010	COG0592	DNA-directed DNA polymerase activity
EOJ31_RS00015	COG2501	S4 domain
EOJ31_RS00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
EOJ31_RS00025	COG0187	DNA topoisomerase II activity
EOJ31_RS00030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EOJ31_RS00035	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
EOJ31_RS00050	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
EOJ31_RS00060	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EOJ31_RS00070	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
EOJ31_RS00075	COG0359	binds to the 23S rRNA
EOJ31_RS00080	COG0305	Participates in initiation and elongation during chromosome replication
EOJ31_RS00100	COG0745	RESPONSE REGULATOR receiver
EOJ31_RS00105	COG5002	protein histidine kinase activity
EOJ31_RS00110	COG4863	YycH protein
EOJ31_RS00120	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
EOJ31_RS00140	COG1063	alcohol dehydrogenase
EOJ31_RS00145	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
EOJ31_RS00255	COG3223	Belongs to the PsiE family
EOJ31_RS00260	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EOJ31_RS00265	COG1733	regulation of RNA biosynthetic process
EOJ31_RS00310	COG2851	Citrate transporter
EOJ31_RS00315	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
EOJ31_RS00320	COG2814	Major facilitator Superfamily
EOJ31_RS00325	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EOJ31_RS00330	COG2226	methyltransferase
EOJ31_RS00335	COG5564	TIM-barrel signal transduction protein
EOJ31_RS00345	COG5564	TIM-barrel signal transduction protein
EOJ31_RS00370	COG2808	Putative FMN-binding domain
EOJ31_RS00375	COG0110	maltose O-acetyltransferase activity
EOJ31_RS00380	COG1114	Component of the transport system for branched-chain amino acids
EOJ31_RS00385	COG2814	Major facilitator Superfamily
EOJ31_RS00425	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EOJ31_RS00430	COG1609	Transcriptional regulator
EOJ31_RS00440	COG1869	D-ribose catabolic process
EOJ31_RS00460	COG2814	Major facilitator Superfamily
EOJ31_RS00480	COG1131	(ABC) transporter
EOJ31_RS00510	COG0601	transmembrane transport
EOJ31_RS00520	COG0444	Belongs to the ABC transporter superfamily
EOJ31_RS00525	COG1124	(ABC) transporter
EOJ31_RS00540	COG0346	lactoylglutathione lyase activity
EOJ31_RS00545	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
EOJ31_RS00595	COG1250	3-hydroxyacyl-CoA dehydrogenase
EOJ31_RS00600	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EOJ31_RS00620	COG2235	arginine
EOJ31_RS00625	COG1438	arginine binding
EOJ31_RS00630	COG0659	secondary active sulfate transmembrane transporter activity
EOJ31_RS00650	COG2814	Major facilitator Superfamily
EOJ31_RS00675	COG0438	transferase activity, transferring glycosyl groups
EOJ31_RS00680	COG0653	protein targeting
EOJ31_RS00690	COG1073	alpha beta
EOJ31_RS00700	COG0201	protein transport
EOJ31_RS00715	COG0747	negative chemotaxis
EOJ31_RS00720	COG0601	transmembrane transport
EOJ31_RS00725	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EOJ31_RS00735	COG1124	(ABC) transporter
EOJ31_RS00740	COG0789	Transcriptional regulator
EOJ31_RS00760	COG2259	Doxx family
EOJ31_RS00770	COG1959	2 iron, 2 sulfur cluster binding
EOJ31_RS00775	COG2910	NAD(P)H-binding
EOJ31_RS00780	COG1876	peptidase activity
EOJ31_RS00785	COG1882	Formate acetyltransferase
EOJ31_RS00790	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
EOJ31_RS00800	COG1288	antiporter activity
EOJ31_RS00805	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EOJ31_RS00810	COG0463	Glycosyl transferase, family 2
EOJ31_RS00810	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
EOJ31_RS00825	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
EOJ31_RS00875	COG1785	Belongs to the alkaline phosphatase family
EOJ31_RS00915	COG0745	RESPONSE REGULATOR receiver
EOJ31_RS00920	COG1131	(ABC) transporter
EOJ31_RS00930	COG2205	protein histidine kinase activity
EOJ31_RS00935	COG1136	(ABC) transporter
EOJ31_RS00950	COG4221	oxidoreductase activity
EOJ31_RS00955	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
EOJ31_RS00960	COG3478	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
EOJ31_RS00965	COG2962	Rard protein
EOJ31_RS00970	COG0471	metal ion transport
EOJ31_RS00980	COG1695	Transcriptional regulator
EOJ31_RS00995	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
EOJ31_RS01000	COG1054	Belongs to the UPF0176 family
EOJ31_RS01025	COG1288	antiporter activity
EOJ31_RS01035	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
EOJ31_RS01055	COG2814	Major facilitator Superfamily
EOJ31_RS01060	COG0737	Belongs to the 5'-nucleotidase family
EOJ31_RS01075	COG3639	organic phosphonate transmembrane transporter activity
EOJ31_RS01140	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EOJ31_RS01160	COG2113	Glycine betaine
EOJ31_RS01165	COG2409	Drug exporters of the RND superfamily
EOJ31_RS01175	COG1764	response to oxidative stress
EOJ31_RS01185	COG3942	CHAP domain
EOJ31_RS01185	COG1705	Flagellar rod assembly protein muramidase FlgJ
EOJ31_RS01205	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EOJ31_RS01215	COG3227	Zinc metalloprotease (Elastase)
EOJ31_RS01220	COG2843	Capsule synthesis protein
EOJ31_RS01235	COG3961	Belongs to the TPP enzyme family
EOJ31_RS01245	COG4195	phage-related replication protein
EOJ31_RS01265	COG0745	RESPONSE REGULATOR receiver
EOJ31_RS01270	COG2205	protein histidine kinase activity
EOJ31_RS01275	COG1136	(ABC) transporter
EOJ31_RS01305	COG0175	sulfate reduction
EOJ31_RS01310	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
EOJ31_RS01315	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EOJ31_RS01330	COG0730	response to heat
EOJ31_RS01335	COG2046	Belongs to the sulfate adenylyltransferase family
EOJ31_RS01340	COG0529	Catalyzes the synthesis of activated sulfate
EOJ31_RS01350	COG3942	CHAP domain
EOJ31_RS01355	COG1328	CTP reductase activity
EOJ31_RS01360	COG0602	queuosine metabolic process
EOJ31_RS01365	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
EOJ31_RS01375	COG1510	regulation of RNA biosynthetic process
EOJ31_RS01380	COG1012	belongs to the aldehyde dehydrogenase family
EOJ31_RS01385	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
EOJ31_RS01390	COG1473	amidohydrolase
EOJ31_RS01410	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EOJ31_RS01415	COG0574	Belongs to the PEP-utilizing enzyme family
EOJ31_RS01415	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EOJ31_RS01420	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
EOJ31_RS01425	COG0579	oxidoreductase
EOJ31_RS01430	COG2723	6-phospho-beta-galactosidase activity
EOJ31_RS01440	COG1695	Transcriptional regulator
EOJ31_RS01450	COG3588	fructose-bisphosphate aldolase
EOJ31_RS01455	COG0563	adenylate kinase activity
EOJ31_RS01465	COG0446	pyridine nucleotide-disulphide oxidoreductase
EOJ31_RS01490	COG0531	amino acid
EOJ31_RS01500	COG0583	DNA-binding transcription factor activity
EOJ31_RS01505	COG0039	L-malate dehydrogenase activity
EOJ31_RS01510	COG0028	Belongs to the TPP enzyme family
EOJ31_RS01515	COG3527	Alpha-acetolactate decarboxylase
EOJ31_RS01525	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
EOJ31_RS01530	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
EOJ31_RS01545	COG4640	response to antibiotic
EOJ31_RS01575	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
EOJ31_RS01585	COG0167	dihydroorotate dehydrogenase activity
EOJ31_RS01590	COG3001	Fructosamine kinase
EOJ31_RS01595	COG0596	Alpha beta hydrolase
EOJ31_RS01605	COG4221	oxidoreductase activity
EOJ31_RS01640	COG1113	amino acid transport
EOJ31_RS01655	COG1388	LysM domain
EOJ31_RS01670	COG0436	Aminotransferase
EOJ31_RS01680	COG2608	mercury ion transmembrane transporter activity
EOJ31_RS01695	COG1028	Short-chain dehydrogenase reductase Sdr
EOJ31_RS01705	COG1012	belongs to the aldehyde dehydrogenase family
EOJ31_RS01735	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EOJ31_RS01740	COG3425	synthase
EOJ31_RS01750	COG1388	LysM domain
EOJ31_RS01750	COG3942	CHAP domain
EOJ31_RS01760	COG0583	DNA-binding transcription factor activity
EOJ31_RS01765	COG1380	Effector of murein hydrolase LrgA
EOJ31_RS01770	COG1346	cytolysis
EOJ31_RS01775	COG0028	Belongs to the TPP enzyme family
EOJ31_RS01800	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EOJ31_RS01805	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EOJ31_RS01810	COG0657	acetylesterase activity
EOJ31_RS01820	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
EOJ31_RS01830	COG2843	Capsule synthesis protein
EOJ31_RS01850	COG1070	Carbohydrate kinase
EOJ31_RS01860	COG1760	l-serine dehydratase
EOJ31_RS01865	COG1760	l-serine dehydratase
EOJ31_RS01880	COG3764	Sortase (surface protein transpeptidase)
EOJ31_RS01885	COG0561	phosphatase activity
EOJ31_RS01895	COG0778	Nitroreductase
EOJ31_RS01900	COG1012	belongs to the aldehyde dehydrogenase family
EOJ31_RS01920	COG2314	TM2 domain
EOJ31_RS01925	COG2514	catechol 2,3-dioxygenase activity
EOJ31_RS01940	COG0583	DNA-binding transcription factor activity
EOJ31_RS01945	COG1012	belongs to the aldehyde dehydrogenase family
EOJ31_RS01950	COG3949	Membrane
EOJ31_RS01960	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
EOJ31_RS01965	COG0586	Pfam SNARE associated Golgi protein
EOJ31_RS01970	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EOJ31_RS01975	COG2022	thiamine diphosphate biosynthetic process
EOJ31_RS01990	COG0352	thiamine-phosphate diphosphorylase activity
EOJ31_RS02000	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
EOJ31_RS02010	COG4876	unkown
EOJ31_RS02015	COG2357	RelA SpoT domain protein
EOJ31_RS02025	COG1802	Transcriptional regulator
EOJ31_RS02030	COG1070	Carbohydrate kinase
EOJ31_RS02035	COG2610	gluconate transmembrane transporter activity
EOJ31_RS02040	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EOJ31_RS02055	COG1215	transferase activity, transferring glycosyl groups
EOJ31_RS02060	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EOJ31_RS02065	COG0494	nUDIX hydrolase
EOJ31_RS02075	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EOJ31_RS02080	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EOJ31_RS02085	COG0022	dehydrogenase e1 component
EOJ31_RS02090	COG0508	dehydrogenase complex catalyzes the overall conversion of
EOJ31_RS02120	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EOJ31_RS02125	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
EOJ31_RS02135	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
EOJ31_RS02140	COG1028	Short-chain dehydrogenase reductase Sdr
EOJ31_RS02150	COG1363	Peptidase, m42
EOJ31_RS02155	COG4808	Protein conserved in bacteria
EOJ31_RS02175	COG0069	glutamate synthase activity
EOJ31_RS02190	COG4619	ABC transporter
EOJ31_RS02195	COG0390	transport system, permease component
EOJ31_RS02200	COG2814	Major facilitator Superfamily
EOJ31_RS02205	COG2272	Belongs to the type-B carboxylesterase lipase family
EOJ31_RS02210	COG0531	amino acid
EOJ31_RS02215	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
EOJ31_RS02240	COG1174	glycine betaine transport
EOJ31_RS02245	COG1346	cytolysis
EOJ31_RS02250	COG1380	Effector of murein hydrolase LrgA
EOJ31_RS02260	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EOJ31_RS02270	COG3477	response to acidic pH
EOJ31_RS02280	COG0706	membrane insertase activity
EOJ31_RS02290	COG0531	amino acid
EOJ31_RS02300	COG1113	amino acid transport
EOJ31_RS02305	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
EOJ31_RS02320	COG2814	Major facilitator Superfamily
EOJ31_RS02325	COG1695	Transcriptional regulator
EOJ31_RS02340	COG1929	Belongs to the glycerate kinase type-1 family
EOJ31_RS02355	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EOJ31_RS02360	COG0741	lytic transglycosylase activity
EOJ31_RS02365	COG0588	phosphoglycerate mutase activity
EOJ31_RS02375	COG2814	Major facilitator Superfamily
EOJ31_RS02380	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EOJ31_RS02385	COG0765	amino acid transport
EOJ31_RS02390	COG1126	abc transporter atp-binding protein
EOJ31_RS02395	COG2348	transferase activity, transferring amino-acyl groups
EOJ31_RS02410	COG0803	Belongs to the bacterial solute-binding protein 9 family
EOJ31_RS02430	COG0747	negative chemotaxis
EOJ31_RS02440	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EOJ31_RS02445	COG2146	nitrite reductase [NAD(P)H] activity
EOJ31_RS02455	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
EOJ31_RS02460	COG1140	nitrate reductase beta subunit
EOJ31_RS02470	COG2181	nitrate reductase activity
EOJ31_RS02480	COG4585	Histidine kinase
EOJ31_RS02490	COG2223	nitrite transmembrane transporter activity
EOJ31_RS02505	COG0778	Nitroreductase
EOJ31_RS02515	COG1301	dicarboxylic acid transport
EOJ31_RS02540	COG1263	PTS System
EOJ31_RS02540	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EOJ31_RS02565	COG1028	Short-chain dehydrogenase reductase Sdr
EOJ31_RS02570	COG0583	DNA-binding transcription factor activity
EOJ31_RS02580	COG1028	Short-chain dehydrogenase reductase Sdr
EOJ31_RS02610	COG0492	ferredoxin-NADP+ reductase activity
EOJ31_RS02615	COG0456	acetyltransferase
EOJ31_RS02620	COG0604	alcohol dehydrogenase
EOJ31_RS02625	COG2822	iron ion transport
EOJ31_RS02630	COG2837	iron assimilation
EOJ31_RS02635	COG0672	)-iron permease
EOJ31_RS02640	COG0805	protein transport
EOJ31_RS02645	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EOJ31_RS02655	COG0463	Glycosyl transferase, family 2
EOJ31_RS02655	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
EOJ31_RS02665	COG0463	Glycosyl transferase, family 2
EOJ31_RS02665	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
EOJ31_RS02670	COG1620	l-lactate permease
EOJ31_RS02680	COG0579	oxidoreductase
EOJ31_RS02730	COG2814	Major facilitator Superfamily
EOJ31_RS02740	COG1566	PFAM secretion protein HlyD family protein
EOJ31_RS02745	COG2814	Major facilitator Superfamily
EOJ31_RS02770	COG0598	Magnesium transport protein CorA
EOJ31_RS02775	COG1304	FMN binding
EOJ31_RS02780	COG0786	glutamate:sodium symporter activity
EOJ31_RS02785	COG1695	Transcriptional regulator
EOJ31_RS02800	COG2094	Belongs to the DNA glycosylase MPG family
EOJ31_RS02810	COG1069	ribulokinase activity
EOJ31_RS02815	COG4152	abc transporter atp-binding protein
EOJ31_RS02820	COG1668	transmembrane transport
EOJ31_RS02825	COG1742	UPF0060 membrane protein
EOJ31_RS02830	COG2017	converts alpha-aldose to the beta-anomer
EOJ31_RS02835	COG2258	MOSC domain
EOJ31_RS02840	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
EOJ31_RS02850	COG1266	CAAX protease self-immunity
EOJ31_RS02855	COG0010	Belongs to the arginase family
EOJ31_RS02860	COG0583	DNA-binding transcription factor activity
EOJ31_RS02875	COG1473	amidohydrolase
EOJ31_RS02880	COG1028	Short-chain dehydrogenase reductase Sdr
EOJ31_RS02900	COG1737	Transcriptional regulator
EOJ31_RS02905	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EOJ31_RS02905	COG1263	PTS System
EOJ31_RS02915	COG0385	Bile acid
EOJ31_RS02920	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EOJ31_RS02940	COG1113	amino acid transport
EOJ31_RS02950	COG1263	PTS System
EOJ31_RS02950	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EOJ31_RS02955	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
EOJ31_RS02970	COG1266	CAAX protease self-immunity
EOJ31_RS02975	COG2378	regulation of single-species biofilm formation
EOJ31_RS02980	COG0483	inositol monophosphate 1-phosphatase activity
EOJ31_RS02985	COG1316	TRANSCRIPTIONal
EOJ31_RS03015	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EOJ31_RS03020	COG2076	Multidrug Resistance protein
EOJ31_RS03025	COG2076	Multidrug Resistance protein
EOJ31_RS03030	COG3942	CHAP domain
EOJ31_RS03045	COG1757	Na H antiporter
EOJ31_RS03050	COG3942	CHAP domain
EOJ31_RS03060	COG1846	Transcriptional regulator
EOJ31_RS03075	COG0829	nickel cation binding
EOJ31_RS03090	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
EOJ31_RS03095	COG0804	urea catabolic process
EOJ31_RS03105	COG0831	urea catabolic process
EOJ31_RS03110	COG4413	Urea transporter
EOJ31_RS03115	COG0765	amino acid transport
EOJ31_RS03120	COG0765	amino acid transport
EOJ31_RS03125	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EOJ31_RS03130	COG1126	abc transporter atp-binding protein
EOJ31_RS03135	COG1960	acyl-CoA dehydrogenase activity
EOJ31_RS03150	COG1268	BioY protein
EOJ31_RS03160	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
EOJ31_RS03165	COG0725	ABC transporter, periplasmic molybdate-binding protein
EOJ31_RS03170	COG4149	molybdate abc transporter
EOJ31_RS03175	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
EOJ31_RS03180	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EOJ31_RS03185	COG0521	Mo-molybdopterin cofactor biosynthetic process
EOJ31_RS03190	COG0315	cyclic pyranopterin monophosphate synthase activity
EOJ31_RS03200	COG1763	Mo-molybdopterin cofactor biosynthetic process
EOJ31_RS03220	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
EOJ31_RS03230	COG2814	Major facilitator Superfamily
EOJ31_RS03245	COG2348	transferase activity, transferring amino-acyl groups
EOJ31_RS03250	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EOJ31_RS03270	COG1028	Short-chain dehydrogenase reductase Sdr
EOJ31_RS03275	COG4975	Glucose uptake
EOJ31_RS03290	COG2252	PERMEase
EOJ31_RS03305	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
EOJ31_RS03310	COG0088	Forms part of the polypeptide exit tunnel
EOJ31_RS03315	COG0089	rRNA binding
EOJ31_RS03320	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
EOJ31_RS03325	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
EOJ31_RS03330	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
EOJ31_RS03335	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
EOJ31_RS03340	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
EOJ31_RS03350	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
EOJ31_RS03355	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
EOJ31_RS03360	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
EOJ31_RS03370	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
EOJ31_RS03375	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
EOJ31_RS03380	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
EOJ31_RS03385	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
EOJ31_RS03390	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
EOJ31_RS03395	COG1841	ribosomal large subunit assembly
EOJ31_RS03405	COG0201	protein transport
EOJ31_RS03410	COG0563	adenylate kinase activity
EOJ31_RS03415	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
EOJ31_RS03425	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
EOJ31_RS03430	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
EOJ31_RS03435	COG0202	RNA polymerase activity
EOJ31_RS03450	COG1122	ATPase activity
EOJ31_RS03465	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
EOJ31_RS03480	COG0789	Transcriptional regulator
EOJ31_RS03495	COG0698	ribose 5-phosphate isomerase
EOJ31_RS03535	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EOJ31_RS03540	COG2130	NADP-dependent
EOJ31_RS03550	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EOJ31_RS03565	COG1302	Protein conserved in bacteria
EOJ31_RS03575	COG2814	Major facilitator Superfamily
EOJ31_RS03580	COG4264	IucA IucC family
EOJ31_RS03585	COG3457	Alanine racemase
EOJ31_RS03590	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
EOJ31_RS03595	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EOJ31_RS03600	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EOJ31_RS03605	COG3314	Sporulation integral membrane protein YlbJ
EOJ31_RS03610	COG2329	Antibiotic biosynthesis monooxygenase
EOJ31_RS03620	COG1988	membrane-bound metal-dependent
EOJ31_RS03625	COG4284	Utp--glucose-1-phosphate uridylyltransferase
EOJ31_RS03630	COG1272	protein, Hemolysin III
EOJ31_RS03645	COG2814	Major facilitator Superfamily
EOJ31_RS03650	COG0489	protein tyrosine kinase activity
EOJ31_RS03705	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
EOJ31_RS03745	COG0561	phosphatase activity
EOJ31_RS03765	COG0640	Transcriptional regulator
EOJ31_RS03770	COG0702	epimerase
EOJ31_RS03775	COG1482	cell wall glycoprotein biosynthetic process
EOJ31_RS03795	COG0783	Belongs to the Dps family
EOJ31_RS03800	COG0813	purine-nucleoside phosphorylase activity
EOJ31_RS03805	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
EOJ31_RS03810	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
EOJ31_RS03815	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
EOJ31_RS03825	COG1854	S-ribosylhomocysteine lyase activity
EOJ31_RS03845	COG5146	pantothenate kinase activity
EOJ31_RS03860	COG0504	CTP synthase activity
EOJ31_RS03870	COG0191	fructose-bisphosphate aldolase activity
EOJ31_RS03875	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EOJ31_RS03885	COG1012	belongs to the aldehyde dehydrogenase family
EOJ31_RS03890	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
EOJ31_RS03895	COG0254	rRNA binding
EOJ31_RS03900	COG1435	thymidine kinase activity
EOJ31_RS03910	COG2890	protein-(glutamine-N5) methyltransferase activity
EOJ31_RS03915	COG0009	L-threonylcarbamoyladenylate synthase
EOJ31_RS03920	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EOJ31_RS03925	COG4475	Protein of unknown function (DUF436)
EOJ31_RS03935	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
EOJ31_RS03940	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
EOJ31_RS03965	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EOJ31_RS03975	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
EOJ31_RS03980	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
EOJ31_RS03985	COG0355	proton-transporting ATP synthase activity, rotational mechanism
EOJ31_RS04000	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EOJ31_RS04015	COG0629	single-stranded DNA binding
EOJ31_RS04020	COG1388	LysM domain
EOJ31_RS04025	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
EOJ31_RS04035	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
EOJ31_RS04040	COG0352	thiamine-phosphate diphosphorylase activity
EOJ31_RS04045	COG0706	membrane insertase activity
EOJ31_RS04050	COG1418	mRNA catabolic process
EOJ31_RS04055	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EOJ31_RS04060	COG1937	Protein conserved in bacteria
EOJ31_RS04075	COG0772	Belongs to the SEDS family
EOJ31_RS04080	COG1181	Belongs to the D-alanine--D-alanine ligase family
EOJ31_RS04085	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
EOJ31_RS04090	COG0513	Belongs to the DEAD box helicase family
EOJ31_RS04100	COG3428	Bacterial PH domain
EOJ31_RS04110	COG0736	holo-[acyl-carrier-protein] synthase activity
EOJ31_RS04115	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EOJ31_RS04125	COG2337	Toxic component of a toxin-antitoxin (TA) module
EOJ31_RS04130	COG2208	phosphoserine phosphatase activity
EOJ31_RS04145	COG1191	sigma factor activity
EOJ31_RS04150	COG2183	response to ionizing radiation
EOJ31_RS04195	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
EOJ31_RS04200	COG0473	3-isopropylmalate dehydrogenase activity
EOJ31_RS04220	COG0028	Belongs to the TPP enzyme family
EOJ31_RS04225	COG0129	dihydroxy-acid dehydratase activity
EOJ31_RS04230	COG0802	atpase or kinase
EOJ31_RS04235	COG1214	PFAM Peptidase M22, glycoprotease
EOJ31_RS04240	COG0456	acetyltransferase
EOJ31_RS04245	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
EOJ31_RS04255	COG0488	(ABC) transporter
EOJ31_RS04270	COG2391	methyltransferase activity
EOJ31_RS04275	COG0425	Belongs to the sulfur carrier protein TusA family
EOJ31_RS04280	COG1609	Transcriptional regulator
EOJ31_RS04285	COG1621	beta-fructofuranosidase activity
EOJ31_RS04290	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EOJ31_RS04300	COG3290	protein histidine kinase activity
EOJ31_RS04345	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
EOJ31_RS04350	COG0459	protein refolding
EOJ31_RS04375	COG1725	Transcriptional regulator
EOJ31_RS04390	COG1131	(ABC) transporter
EOJ31_RS04435	COG2706	6-phosphogluconolactonase activity
EOJ31_RS04440	COG1012	belongs to the aldehyde dehydrogenase family
EOJ31_RS04445	COG1227	inorganic diphosphatase activity
EOJ31_RS04450	COG1335	isochorismatase
EOJ31_RS04460	COG0077	Prephenate dehydratase
EOJ31_RS04470	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
EOJ31_RS04475	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
EOJ31_RS04480	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
EOJ31_RS04490	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
EOJ31_RS04495	COG4496	protein, YerC YecD
EOJ31_RS04500	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
EOJ31_RS04505	COG0210	DNA helicase
EOJ31_RS04510	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
EOJ31_RS04520	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EOJ31_RS04535	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EOJ31_RS04540	COG1597	lipid kinase activity
EOJ31_RS04545	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EOJ31_RS04565	COG1528	Iron-storage protein
EOJ31_RS04580	COG4129	membrane
EOJ31_RS04585	COG0024	Methionine aminopeptidase
EOJ31_RS04605	COG2197	response regulator
EOJ31_RS04610	COG1295	ribonuclease BN
EOJ31_RS04625	COG4840	Belongs to the UPF0435 family
EOJ31_RS04630	COG2309	aminopeptidase activity
EOJ31_RS04640	COG0535	radical SAM domain protein
EOJ31_RS04650	COG0693	protein deglycase activity
EOJ31_RS04655	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EOJ31_RS04670	COG1134	teichoic acid transport
EOJ31_RS04670	COG1388	LysM domain
EOJ31_RS04680	COG1988	membrane-bound metal-dependent
EOJ31_RS04685	COG1194	a g-specific adenine glycosylase
EOJ31_RS04690	COG3557	Belongs to the UPF0374 family
EOJ31_RS04700	COG4129	membrane
EOJ31_RS04705	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
EOJ31_RS04710	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EOJ31_RS04715	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EOJ31_RS04720	COG0735	belongs to the Fur family
EOJ31_RS04895	COG0765	amino acid transport
EOJ31_RS04900	COG1126	abc transporter atp-binding protein
EOJ31_RS04905	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
EOJ31_RS04915	COG0363	glucosamine-6-phosphate deaminase activity
EOJ31_RS04930	COG0114	fumarate hydratase activity
EOJ31_RS04935	COG0564	pseudouridine synthase activity
EOJ31_RS04940	COG2203	Gaf domain
EOJ31_RS04940	COG4585	Histidine kinase
EOJ31_RS04945	COG2197	response regulator
EOJ31_RS04955	COG4399	Belongs to the UPF0754 family
EOJ31_RS04960	COG3679	Belongs to the UPF0342 family
EOJ31_RS04965	COG0420	3'-5' exonuclease activity
EOJ31_RS04975	COG3481	metal-dependent phosphohydrolase, HD sub domain
EOJ31_RS04985	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EOJ31_RS05000	COG0537	adenosine 5'-monophosphoramidase activity
EOJ31_RS05005	COG1131	(ABC) transporter
EOJ31_RS05010	COG4473	ABC transporter
EOJ31_RS05015	COG2329	Antibiotic biosynthesis monooxygenase
EOJ31_RS05025	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
EOJ31_RS05030	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
EOJ31_RS05035	COG3545	Serine hydrolase
EOJ31_RS05115	COG3620	sequence-specific DNA binding
EOJ31_RS05180	COG1484	DNA-dependent DNA replication
EOJ31_RS05300	COG0740	serine-type endopeptidase activity
EOJ31_RS05350	COG0739	heme binding
EOJ31_RS05440	COG0318	PFAM AMP-dependent synthetase and ligase
EOJ31_RS05455	COG0494	nUDIX hydrolase
EOJ31_RS05460	COG1506	peptidase
EOJ31_RS05470	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
EOJ31_RS05480	COG0656	L-ascorbic acid biosynthetic process
EOJ31_RS05485	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EOJ31_RS05490	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EOJ31_RS05500	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
EOJ31_RS05525	COG5632	N-Acetylmuramoyl-L-alanine amidase
EOJ31_RS05525	COG4193	domain, Protein
EOJ31_RS05525	COG3266	domain, Protein
EOJ31_RS05535	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EOJ31_RS05535	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EOJ31_RS05540	COG0307	riboflavin synthase, alpha
EOJ31_RS05545	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EOJ31_RS05545	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EOJ31_RS05550	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
EOJ31_RS05560	COG2267	carboxylic ester hydrolase activity
EOJ31_RS05570	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
EOJ31_RS05575	COG1242	4 iron, 4 sulfur cluster binding
EOJ31_RS05580	COG2814	Major facilitator Superfamily
EOJ31_RS05585	COG0495	leucyl-tRNA aminoacylation
EOJ31_RS05590	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EOJ31_RS05605	COG2081	HI0933 family
EOJ31_RS05610	COG2244	polysaccharide biosynthetic process
EOJ31_RS05615	COG1187	pseudouridine synthase activity
EOJ31_RS05625	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EOJ31_RS05630	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EOJ31_RS05635	COG0510	thiamine kinase activity
EOJ31_RS05640	COG0220	tRNA (guanine-N7-)-methyltransferase activity
EOJ31_RS05645	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EOJ31_RS05655	COG1363	Peptidase, m42
EOJ31_RS05660	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EOJ31_RS05665	COG4848	Belongs to the UPF0354 family
EOJ31_RS05670	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EOJ31_RS05675	COG1674	ftsk spoiiie
EOJ31_RS05680	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
EOJ31_RS05695	COG1605	Chorismate mutase
EOJ31_RS05695	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
EOJ31_RS05700	COG1609	Transcriptional regulator
EOJ31_RS05710	COG0454	-acetyltransferase
EOJ31_RS05715	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EOJ31_RS05725	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
EOJ31_RS05740	COG2814	Major facilitator Superfamily
EOJ31_RS05745	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EOJ31_RS05750	COG0204	Acyl-transferase
EOJ31_RS05770	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EOJ31_RS05770	COG1263	PTS System
EOJ31_RS05780	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EOJ31_RS05785	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
EOJ31_RS05790	COG1764	response to oxidative stress
EOJ31_RS05795	COG0584	glycerophosphoryl diester phosphodiesterase
EOJ31_RS05800	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
EOJ31_RS05805	COG1956	GAF domain-containing protein
EOJ31_RS05810	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
EOJ31_RS05815	COG1104	cysteine desulfurase activity
EOJ31_RS05820	COG0301	tRNA thio-modification
EOJ31_RS05830	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
EOJ31_RS05835	COG0827	DNA restriction-modification system
EOJ31_RS05840	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
EOJ31_RS05845	COG0589	response to stress
EOJ31_RS05850	COG0686	Belongs to the AlaDH PNT family
EOJ31_RS05855	COG0006	proline dipeptidase activity
EOJ31_RS05860	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
EOJ31_RS05870	COG4109	DRTGG domain
EOJ31_RS05875	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
EOJ31_RS05880	COG0587	DNA-directed DNA polymerase activity
EOJ31_RS05885	COG0281	malic enzyme
EOJ31_RS05890	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
EOJ31_RS05900	COG0205	6-phosphofructokinase activity
EOJ31_RS05905	COG0469	pyruvate kinase activity
EOJ31_RS05910	COG1113	amino acid transport
EOJ31_RS05915	COG0372	Belongs to the citrate synthase family
EOJ31_RS05920	COG0538	isocitrate dehydrogenase activity
EOJ31_RS05925	COG0745	RESPONSE REGULATOR receiver
EOJ31_RS05930	COG5002	protein histidine kinase activity
EOJ31_RS05935	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EOJ31_RS05935	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EOJ31_RS05940	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
EOJ31_RS05950	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EOJ31_RS05955	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
EOJ31_RS05960	COG3611	Membrane attachment protein
EOJ31_RS05965	COG1484	DNA-dependent DNA replication
EOJ31_RS05975	COG0833	amino acid
EOJ31_RS05980	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
EOJ31_RS05985	COG0291	Belongs to the bacterial ribosomal protein bL35 family
EOJ31_RS05990	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
EOJ31_RS05995	COG4112	unkown
EOJ31_RS06005	COG0544	peptidyl-prolyl cis-trans isomerase activity
EOJ31_RS06010	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
EOJ31_RS06015	COG0218	Necessary for normal cell division and for the maintenance of normal septation
EOJ31_RS06020	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
EOJ31_RS06025	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EOJ31_RS06030	COG0181	hydroxymethylbilane synthase activity
EOJ31_RS06040	COG0113	porphobilinogen synthase activity
EOJ31_RS06045	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
EOJ31_RS06055	COG2818	Glycosylase
EOJ31_RS06060	COG0525	valine-tRNA ligase activity
EOJ31_RS06065	COG0285	dihydrofolate synthase activity
EOJ31_RS06075	COG2003	Belongs to the UPF0758 family
EOJ31_RS06110	COG0261	This protein binds to 23S rRNA in the presence of protein L20
EOJ31_RS06115	COG2868	ribosomal protein
EOJ31_RS06120	COG0211	Belongs to the bacterial ribosomal protein bL27 family
EOJ31_RS06125	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
EOJ31_RS06130	COG4492	Belongs to the UPF0735 family
EOJ31_RS06135	COG0632	four-way junction helicase activity
EOJ31_RS06145	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
EOJ31_RS06155	COG1862	Preprotein translocase
EOJ31_RS06160	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EOJ31_RS06160	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EOJ31_RS06165	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
EOJ31_RS06165	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
EOJ31_RS06175	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EOJ31_RS06185	COG0860	N-Acetylmuramoyl-L-alanine amidase
EOJ31_RS06195	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
EOJ31_RS06205	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
EOJ31_RS06210	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
EOJ31_RS06215	COG1959	2 iron, 2 sulfur cluster binding
EOJ31_RS06225	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EOJ31_RS06230	COG1104	cysteine desulfurase activity
EOJ31_RS06235	COG0482	sulfurtransferase activity
EOJ31_RS06245	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
EOJ31_RS06255	COG4472	Bacterial protein of unknown function (DUF965)
EOJ31_RS06265	COG3906	Belongs to the UPF0473 family
EOJ31_RS06270	COG4122	O-methyltransferase activity
EOJ31_RS06275	COG0826	peptidase U32
EOJ31_RS06280	COG0826	peptidase U32
EOJ31_RS06285	COG0572	uridine kinase
EOJ31_RS06290	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EOJ31_RS06295	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
EOJ31_RS06300	COG1984	allophanate hydrolase subunit 2
EOJ31_RS06305	COG0511	ligase activity, forming carbon-carbon bonds
EOJ31_RS06310	COG0439	Biotin carboxylase
EOJ31_RS06320	COG1914	H( )-stimulated, divalent metal cation uptake system
EOJ31_RS06325	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EOJ31_RS06330	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
EOJ31_RS06335	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
EOJ31_RS06340	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
EOJ31_RS06345	COG1534	Rna-binding protein
EOJ31_RS06350	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
EOJ31_RS06355	COG1713	HD superfamily hydrolase involved in NAD metabolism
EOJ31_RS06360	COG0799	negative regulation of ribosome biogenesis
EOJ31_RS06375	COG2131	deaminase
EOJ31_RS06380	COG2333	competence protein COMEC
EOJ31_RS06380	COG0658	competence protein
EOJ31_RS06385	COG1466	dna polymerase III delta subunit
EOJ31_RS06390	COG0268	Binds directly to 16S ribosomal RNA
EOJ31_RS06395	COG0481	GTPase activity
EOJ31_RS06400	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EOJ31_RS06410	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
EOJ31_RS06415	COG0443	Heat shock 70 kDa protein
EOJ31_RS06420	COG0484	heat shock protein binding
EOJ31_RS06430	COG1385	rRNA (uridine-N3-)-methyltransferase activity
EOJ31_RS06435	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EOJ31_RS06445	COG1030	water channel activity
EOJ31_RS06450	COG4864	UPF0365 protein
EOJ31_RS06460	COG1702	phosphate starvation-inducible protein PhoH
EOJ31_RS06480	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
EOJ31_RS06485	COG1381	Involved in DNA repair and RecF pathway recombination
EOJ31_RS06490	COG0423	glycine-tRNA ligase activity
EOJ31_RS06495	COG0517	IMP dehydrogenase activity
EOJ31_RS06500	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
EOJ31_RS06510	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EOJ31_RS06515	COG2384	SAM-dependent methyltransferase
EOJ31_RS06520	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
EOJ31_RS06525	COG0513	Belongs to the DEAD box helicase family
EOJ31_RS06530	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
EOJ31_RS06535	COG1121	(ABC) transporter
EOJ31_RS06540	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EOJ31_RS06555	COG0768	penicillin binding
EOJ31_RS06560	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EOJ31_RS06565	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
EOJ31_RS06575	COG4483	Protein conserved in bacteria
EOJ31_RS06580	COG1940	carbohydrate kinase activity
EOJ31_RS06585	COG0011	TIGRFAM Protein of
EOJ31_RS06590	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EOJ31_RS06595	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EOJ31_RS06600	COG1459	type II secretion system
EOJ31_RS06605	COG4537	Required for transformation and DNA binding
EOJ31_RS06615	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
EOJ31_RS06620	COG0404	The glycine cleavage system catalyzes the degradation of glycine
EOJ31_RS06635	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EOJ31_RS06640	COG0095	Lipoate-protein ligase
EOJ31_RS06655	COG0006	proline dipeptidase activity
EOJ31_RS06660	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
EOJ31_RS06665	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
EOJ31_RS06670	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
EOJ31_RS06675	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
EOJ31_RS06680	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EOJ31_RS06685	COG0511	ligase activity, forming carbon-carbon bonds
EOJ31_RS06690	COG0439	Biotin carboxylase
EOJ31_RS06695	COG1302	Protein conserved in bacteria
EOJ31_RS06700	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EOJ31_RS06710	COG1722	exodeoxyribonuclease VII activity
EOJ31_RS06715	COG0142	geranyltranstransferase activity
EOJ31_RS06720	COG1438	arginine binding
EOJ31_RS06725	COG0497	DNA recombination
EOJ31_RS06730	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EOJ31_RS06735	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EOJ31_RS06740	COG0022	dehydrogenase e1 component
EOJ31_RS06745	COG0508	dehydrogenase complex catalyzes the overall conversion of
EOJ31_RS06755	COG4129	membrane
EOJ31_RS06760	COG2195	Cleaves the N-terminal amino acid of tripeptides
EOJ31_RS06765	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
EOJ31_RS06770	COG0366	Alpha amylase catalytic
EOJ31_RS06780	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
EOJ31_RS06785	COG1234	tRNA 3'-trailer cleavage
EOJ31_RS06790	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EOJ31_RS06795	COG1028	Short-chain dehydrogenase reductase Sdr
EOJ31_RS06800	COG0667	Aldo Keto reductase
EOJ31_RS06805	COG0494	nUDIX hydrolase
EOJ31_RS06810	COG0735	belongs to the Fur family
EOJ31_RS06815	COG4974	Belongs to the 'phage' integrase family
EOJ31_RS06825	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
EOJ31_RS06830	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
EOJ31_RS06835	COG1187	pseudouridine synthase activity
EOJ31_RS06840	COG0745	RESPONSE REGULATOR receiver
EOJ31_RS06855	COG1141	Ferredoxin
EOJ31_RS06865	COG0514	ATP-dependent DNA helicase (RecQ)
EOJ31_RS06875	COG0492	ferredoxin-NADP+ reductase activity
EOJ31_RS06880	COG0252	asparaginase activity
EOJ31_RS06885	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
EOJ31_RS06890	COG0539	negative regulation of cytoplasmic translation
EOJ31_RS06895	COG1160	GTP binding
EOJ31_RS06900	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
EOJ31_RS06915	COG2226	methyltransferase
EOJ31_RS06930	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
EOJ31_RS06935	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
EOJ31_RS06950	COG5582	Belongs to the UPF0302 family
EOJ31_RS06955	COG4347	Protein of unknown function (DUF1405)
EOJ31_RS06960	COG2738	Putative neutral zinc metallopeptidase
EOJ31_RS06965	COG1694	Mazg nucleotide pyrophosphohydrolase
EOJ31_RS06970	COG0438	transferase activity, transferring glycosyl groups
EOJ31_RS06975	COG0617	tRNA 3'-terminal CCA addition
EOJ31_RS06980	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
EOJ31_RS06980	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
EOJ31_RS06985	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EOJ31_RS06985	COG1199	ATP-dependent helicase activity
EOJ31_RS06990	COG0017	Asparaginyl-tRNA synthetase
EOJ31_RS06995	COG3935	DnaD domain protein
EOJ31_RS07000	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
EOJ31_RS07010	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EOJ31_RS07010	COG4499	WXG100 protein secretion system (Wss), protein YukC
EOJ31_RS07015	COG3331	DNA recombination
EOJ31_RS07030	COG3599	regulation of cell shape
EOJ31_RS07040	COG0116	Belongs to the methyltransferase superfamily
EOJ31_RS07050	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
EOJ31_RS07055	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EOJ31_RS07070	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
EOJ31_RS07080	COG1413	lyase activity
EOJ31_RS07085	COG1413	lyase activity
EOJ31_RS07115	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EOJ31_RS07120	COG2190	(PTS) system
EOJ31_RS07130	COG0793	Belongs to the peptidase S41A family
EOJ31_RS07140	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
EOJ31_RS07145	COG0671	phosphoesterase, PA-phosphatase related
EOJ31_RS07150	COG0745	RESPONSE REGULATOR receiver
EOJ31_RS07155	COG5002	protein histidine kinase activity
EOJ31_RS07160	COG0567	Dehydrogenase, E1 component
EOJ31_RS07165	COG0508	dehydrogenase complex catalyzes the overall conversion of
EOJ31_RS07170	COG1131	(ABC) transporter
EOJ31_RS07195	COG0714	Associated with various cellular activities
EOJ31_RS07200	COG4548	von Willebrand factor, type A
EOJ31_RS07205	COG1114	Component of the transport system for branched-chain amino acids
EOJ31_RS07210	COG3853	Toxic anion resistance protein (TelA)
EOJ31_RS07220	COG1254	Belongs to the acylphosphatase family
EOJ31_RS07230	COG1278	Cold shock
EOJ31_RS07245	COG1473	amidohydrolase
EOJ31_RS07255	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
EOJ31_RS07260	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EOJ31_RS07265	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EOJ31_RS07270	COG0527	aspartate kinase activity
EOJ31_RS07275	COG0488	(ABC) transporter
EOJ31_RS07280	COG2996	Protein conserved in bacteria
EOJ31_RS07285	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
EOJ31_RS07290	COG0573	inorganic phosphate transmembrane transporter activity
EOJ31_RS07295	COG0581	inorganic phosphate transmembrane transporter activity
EOJ31_RS07300	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
EOJ31_RS07340	COG4607	ABC-type enterochelin transport system periplasmic component
EOJ31_RS07350	COG2348	transferase activity, transferring amino-acyl groups
EOJ31_RS07355	COG2348	transferase activity, transferring amino-acyl groups
EOJ31_RS07375	COG0134	indole-3-glycerol-phosphate synthase activity
EOJ31_RS07385	COG0512	Glutamine amidotransferase of anthranilate synthase
EOJ31_RS07390	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EOJ31_RS07395	COG1363	Peptidase, m42
EOJ31_RS07400	COG0287	Prephenate dehydrogenase
EOJ31_RS07405	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EOJ31_RS07410	COG1942	4-Oxalocrotonate Tautomerase
EOJ31_RS07425	COG0392	lysyltransferase activity
EOJ31_RS07425	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
EOJ31_RS07430	COG0628	permease
EOJ31_RS07435	COG3711	transcriptional antiterminator
EOJ31_RS07440	COG1115	amino acid carrier protein
EOJ31_RS07445	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EOJ31_RS07450	COG0187	DNA topoisomerase II activity
EOJ31_RS07465	COG0824	Thioesterase
EOJ31_RS07470	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
EOJ31_RS07475	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EOJ31_RS07480	COG1970	mechanosensitive ion channel activity
EOJ31_RS07495	COG4846	Membrane protein involved in cytochrome C biogenesis
EOJ31_RS07505	COG3763	UPF0154 protein
EOJ31_RS07515	COG4224	UPF0291 protein
EOJ31_RS07540	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
EOJ31_RS07555	COG0833	amino acid
EOJ31_RS07570	COG0083	homoserine kinase activity
EOJ31_RS07575	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
EOJ31_RS07580	COG0460	homoserine dehydrogenase
EOJ31_RS07585	COG0527	aspartate kinase activity
EOJ31_RS07600	COG1525	nuclease
EOJ31_RS07615	COG2197	response regulator
EOJ31_RS07630	COG1131	(ABC) transporter
EOJ31_RS07670	COG0789	Transcriptional regulator
EOJ31_RS07675	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
EOJ31_RS07680	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EOJ31_RS07685	COG0386	Belongs to the glutathione peroxidase family
EOJ31_RS07690	COG1923	regulation of RNA biosynthetic process
EOJ31_RS07695	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
EOJ31_RS07705	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
EOJ31_RS07715	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
EOJ31_RS07720	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
EOJ31_RS07725	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
EOJ31_RS07740	COG4550	Control of competence regulator ComK, YlbF/YmcA
EOJ31_RS07745	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EOJ31_RS07755	COG4195	phage-related replication protein
EOJ31_RS07760	COG1013	pyruvate-flavodoxin oxidoreductase activity
EOJ31_RS07765	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
EOJ31_RS07765	COG0674	pyruvate-flavodoxin oxidoreductase activity
EOJ31_RS07770	COG1692	metallophosphoesterase
EOJ31_RS07780	COG1418	mRNA catabolic process
EOJ31_RS07785	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
EOJ31_RS07790	COG1546	Belongs to the CinA family
EOJ31_RS07790	COG1058	Belongs to the CinA family
EOJ31_RS07800	COG1426	Protein conserved in bacteria
EOJ31_RS07810	COG1028	Short-chain dehydrogenase reductase Sdr
EOJ31_RS07815	COG0612	Peptidase, M16
EOJ31_RS07820	COG0612	Peptidase, M16
EOJ31_RS07825	COG2188	Transcriptional regulator
EOJ31_RS07835	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EOJ31_RS07840	COG1185	polyribonucleotide nucleotidyltransferase activity
EOJ31_RS07845	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
EOJ31_RS07850	COG0196	riboflavin kinase activity
EOJ31_RS07855	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
EOJ31_RS07860	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
EOJ31_RS07865	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
EOJ31_RS07870	COG1358	cellular component organization or biogenesis
EOJ31_RS07875	COG2740	Nucleic-acid-binding protein implicated in transcription termination
EOJ31_RS07880	COG0195	Participates in both transcription termination and antitermination
EOJ31_RS07885	COG0779	Required for maturation of 30S ribosomal subunits
EOJ31_RS07890	COG2176	DNA-directed DNA polymerase activity
EOJ31_RS07895	COG0442	prolyl-tRNA aminoacylation
EOJ31_RS07905	COG4589	Belongs to the CDS family
EOJ31_RS07910	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
EOJ31_RS07915	COG0233	cytoplasmic translational termination
EOJ31_RS07920	COG0528	UMP kinase activity
EOJ31_RS07925	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
EOJ31_RS07930	COG0052	Belongs to the universal ribosomal protein uS2 family
EOJ31_RS07945	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
EOJ31_RS07950	COG4974	Belongs to the 'phage' integrase family
EOJ31_RS07955	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
EOJ31_RS07960	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EOJ31_RS07965	COG0758	DNA mediated transformation
EOJ31_RS07970	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
EOJ31_RS07975	COG0045	succinate-CoA ligase (ADP-forming) activity
EOJ31_RS07980	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EOJ31_RS07990	COG4485	Bacterial membrane protein, YfhO
EOJ31_RS08005	COG0336	Belongs to the RNA methyltransferase TrmD family
EOJ31_RS08010	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
EOJ31_RS08015	COG0228	four-way junction DNA binding
EOJ31_RS08020	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EOJ31_RS08025	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
EOJ31_RS08030	COG0552	protein localization to endoplasmic reticulum
EOJ31_RS08035	COG1196	nuclear chromosome segregation
EOJ31_RS08040	COG0571	ribonuclease III activity
EOJ31_RS08045	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EOJ31_RS08060	COG0416	fatty acid biosynthetic process
EOJ31_RS08065	COG1349	DNA-binding transcription factor activity
EOJ31_RS08070	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
EOJ31_RS08075	COG1461	Dihydroxyacetone kinase
EOJ31_RS08080	COG1302	Protein conserved in bacteria
EOJ31_RS08085	COG0227	Belongs to the bacterial ribosomal protein bL28 family
EOJ31_RS08095	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
EOJ31_RS08110	COG0631	protein serine/threonine phosphatase activity
EOJ31_RS08115	COG0820	rRNA (adenine-C2-)-methyltransferase activity
EOJ31_RS08120	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EOJ31_RS08120	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EOJ31_RS08125	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EOJ31_RS08130	COG0242	peptide deformylase activity
EOJ31_RS08140	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EOJ31_RS08145	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EOJ31_RS08150	COG1758	RNA polymerase activity
EOJ31_RS08155	COG0194	GDP metabolic process
EOJ31_RS08175	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
EOJ31_RS08180	COG0284	orotidine-5'-phosphate decarboxylase activity
EOJ31_RS08185	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
EOJ31_RS08190	COG0505	Belongs to the CarA family
EOJ31_RS08195	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
EOJ31_RS08200	COG0540	Belongs to the ATCase OTCase family
EOJ31_RS08205	COG2233	PERMEase
EOJ31_RS08210	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
EOJ31_RS08220	COG0564	pseudouridine synthase activity
EOJ31_RS08230	COG1388	LysM domain
EOJ31_RS08230	COG3942	CHAP domain
EOJ31_RS08240	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
EOJ31_RS08245	COG3599	regulation of cell shape
EOJ31_RS08255	COG0762	integral membrane protein
EOJ31_RS08260	COG1799	cell septum assembly
EOJ31_RS08265	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
EOJ31_RS08270	COG1496	oxidoreductase activity
EOJ31_RS08275	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
EOJ31_RS08280	COG0849	cell division
EOJ31_RS08285	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
EOJ31_RS08295	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EOJ31_RS08300	COG0768	penicillin binding
EOJ31_RS08305	COG4839	cell division protein FtsL
EOJ31_RS08310	COG0275	rRNA processing
EOJ31_RS08320	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
EOJ31_RS08330	COG1011	Hydrolase
EOJ31_RS08370	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
EOJ31_RS08375	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
EOJ31_RS08380	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
EOJ31_RS08385	COG1053	succinate dehydrogenase
EOJ31_RS08390	COG2009	succinate dehydrogenase
EOJ31_RS08395	COG0322	excinuclease ABC activity
EOJ31_RS08400	COG3118	belongs to the thioredoxin family
EOJ31_RS08405	COG1193	negative regulation of DNA recombination
EOJ31_RS08410	COG1796	DNA polymerase
EOJ31_RS08410	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
EOJ31_RS08420	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
EOJ31_RS08425	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EOJ31_RS08430	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EOJ31_RS08430	COG0072	phenylalanine-tRNA ligase activity
EOJ31_RS08435	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
EOJ31_RS08440	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EOJ31_RS08445	COG0333	Belongs to the bacterial ribosomal protein bL32 family
EOJ31_RS08460	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
EOJ31_RS08465	COG0742	ribosomal rna small subunit methyltransferase
EOJ31_RS08480	COG0584	glycerophosphoryl diester phosphodiesterase
EOJ31_RS08485	COG3679	Belongs to the UPF0342 family
EOJ31_RS08500	COG0109	protoheme IX farnesyltransferase activity
EOJ31_RS08505	COG1612	heme a metabolic process
EOJ31_RS08515	COG0772	Belongs to the SEDS family
EOJ31_RS08520	COG4838	Belongs to the UPF0358 family
EOJ31_RS08525	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
EOJ31_RS08530	COG4896	Protein conserved in bacteria
EOJ31_RS08535	COG1217	gtp-binding protein TYPA
EOJ31_RS08545	COG0483	inositol monophosphate 1-phosphatase activity
EOJ31_RS08550	COG4493	Belongs to the UPF0637 family
EOJ31_RS08580	COG1176	ABC-type spermidine putrescine transport system, permease component I
EOJ31_RS08595	COG4476	Belongs to the UPF0223 family
EOJ31_RS08605	COG0508	dehydrogenase complex catalyzes the overall conversion of
EOJ31_RS08625	COG0242	peptide deformylase activity
EOJ31_RS08630	COG5503	Protein of unknown function (DUF1447)
EOJ31_RS08635	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EOJ31_RS08640	COG0569	domain protein
EOJ31_RS08645	COG1294	oxidase, subunit
EOJ31_RS08650	COG1271	oxidase subunit
EOJ31_RS08660	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EOJ31_RS08665	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EOJ31_RS08675	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
EOJ31_RS08690	COG4172	Belongs to the ABC transporter superfamily
EOJ31_RS08695	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EOJ31_RS08700	COG0151	Belongs to the GarS family
EOJ31_RS08705	COG0138	bifunctional purine biosynthesis protein purh
EOJ31_RS08715	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
EOJ31_RS08730	COG0047	phosphoribosylformylglycinamidine synthase activity
EOJ31_RS08735	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EOJ31_RS08740	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
EOJ31_RS08750	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
EOJ31_RS08755	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
EOJ31_RS08760	COG1017	nitric oxide dioxygenase activity
EOJ31_RS08760	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EOJ31_RS08770	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
EOJ31_RS08785	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
EOJ31_RS08800	COG1316	TRANSCRIPTIONal
EOJ31_RS08825	COG3594	Acyltransferase
EOJ31_RS08830	COG0436	Aminotransferase
EOJ31_RS08835	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
EOJ31_RS08845	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
EOJ31_RS08850	COG1169	isochorismate synthase
EOJ31_RS08855	COG1575	Belongs to the MenA family. Type 1 subfamily
EOJ31_RS08860	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EOJ31_RS08865	COG2314	TM2 domain
EOJ31_RS08900	COG4873	Protein conserved in bacteria
EOJ31_RS08915	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EOJ31_RS08920	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EOJ31_RS08925	COG0861	Integral membrane protein TerC family
EOJ31_RS08930	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
EOJ31_RS08940	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EOJ31_RS08945	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
EOJ31_RS08950	COG2814	Major facilitator Superfamily
EOJ31_RS08955	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
EOJ31_RS08960	COG2382	esterase
EOJ31_RS08965	COG1115	amino acid carrier protein
EOJ31_RS08970	COG0628	permease
EOJ31_RS08980	COG0475	glutathione-regulated potassium exporter activity
EOJ31_RS08980	COG0569	domain protein
EOJ31_RS08985	COG2239	Acts as a magnesium transporter
EOJ31_RS08990	COG0564	pseudouridine synthase activity
EOJ31_RS08995	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
EOJ31_RS09000	COG2357	RelA SpoT domain protein
EOJ31_RS09015	COG2346	COG2346, Truncated hemoglobins
EOJ31_RS09020	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
EOJ31_RS09025	COG1164	Oligoendopeptidase f
EOJ31_RS09035	COG4862	establishment of competence for transformation
EOJ31_RS09040	COG1393	Belongs to the ArsC family
EOJ31_RS09045	COG0180	Tryptophanyl-tRNA synthetase
EOJ31_RS09050	COG4166	transmembrane transport
EOJ31_RS09055	COG4608	Belongs to the ABC transporter superfamily
EOJ31_RS09060	COG0444	Belongs to the ABC transporter superfamily
EOJ31_RS09065	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EOJ31_RS09070	COG0601	transmembrane transport
EOJ31_RS09085	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EOJ31_RS09095	COG0542	response to heat
EOJ31_RS09110	COG0561	phosphatase activity
EOJ31_RS09115	COG0446	pyridine nucleotide-disulphide oxidoreductase
EOJ31_RS09130	COG1074	ATP-dependent DNA helicase activity
EOJ31_RS09150	COG0398	Pfam SNARE associated Golgi protein
EOJ31_RS09160	COG0137	argininosuccinate synthase activity
EOJ31_RS09165	COG0165	Argininosuccinate lyase
EOJ31_RS09170	COG0584	glycerophosphoryl diester phosphodiesterase
EOJ31_RS09175	COG0584	glycerophosphoryl diester phosphodiesterase
EOJ31_RS09195	COG1902	pentaerythritol trinitrate reductase activity
EOJ31_RS09200	COG1098	S1 RNA binding domain
EOJ31_RS09215	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EOJ31_RS09215	COG2111	Na H antiporter
EOJ31_RS09220	COG2111	Na H antiporter
EOJ31_RS09225	COG1006	Multisubunit Na H antiporter MnhC subunit
EOJ31_RS09230	COG0651	ATP synthesis coupled electron transport
EOJ31_RS09240	COG2212	antiporter activity
EOJ31_RS09260	COG2050	protein possibly involved in aromatic compounds catabolism
EOJ31_RS09265	COG2056	Na+-H+ antiporter family
EOJ31_RS09270	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
EOJ31_RS09280	COG0316	Belongs to the HesB IscA family
EOJ31_RS09285	COG4844	belongs to the
EOJ31_RS09290	COG1252	NADH dehydrogenase
EOJ31_RS09295	COG4837	Protein of unknown function (DUF1462)
EOJ31_RS09300	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
EOJ31_RS09305	COG0583	DNA-binding transcription factor activity
EOJ31_RS09315	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
EOJ31_RS09325	COG1696	Membrane protein involved in D-alanine export
EOJ31_RS09330	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EOJ31_RS09350	COG2445	Protein of unknown function DUF86
EOJ31_RS09360	COG4470	Protein conserved in bacteria
EOJ31_RS09365	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
EOJ31_RS09370	COG0737	Belongs to the 5'-nucleotidase family
EOJ31_RS09375	COG0730	response to heat
EOJ31_RS09380	COG1801	Protein of unknown function DUF72
EOJ31_RS09385	COG2070	2-Nitropropane dioxygenase
EOJ31_RS09390	COG1253	flavin adenine dinucleotide binding
EOJ31_RS09395	COG0719	Fe-S assembly protein
EOJ31_RS09400	COG0822	iron-sulfur transferase activity
EOJ31_RS09405	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EOJ31_RS09410	COG0719	Fe-S assembly protein
EOJ31_RS09415	COG0396	ATPase activity
EOJ31_RS09425	COG3237	CsbD-like
EOJ31_RS09430	COG1464	Belongs to the NlpA lipoprotein family
EOJ31_RS09435	COG2011	ABC-type metal ion transport system permease component
EOJ31_RS09440	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
EOJ31_RS09450	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
EOJ31_RS09455	COG0509	glycine decarboxylation via glycine cleavage system
EOJ31_RS09460	COG1393	Belongs to the ArsC family
EOJ31_RS09465	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EOJ31_RS09475	COG0710	3-dehydroquinate dehydratase activity
EOJ31_RS09480	COG1764	response to oxidative stress
EOJ31_RS09490	COG0406	alpha-ribazole phosphatase activity
EOJ31_RS09525	COG4195	phage-related replication protein
EOJ31_RS09550	COG1278	Cold shock
EOJ31_RS09575	COG0656	L-ascorbic acid biosynthetic process
EOJ31_RS09580	COG1309	transcriptional regulator
EOJ31_RS09640	COG0557	exoribonuclease II activity
EOJ31_RS09645	COG1647	Serine aminopeptidase, S33
EOJ31_RS09650	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EOJ31_RS09660	COG0148	phosphopyruvate hydratase activity
EOJ31_RS09665	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
EOJ31_RS09670	COG0149	triose-phosphate isomerase activity
EOJ31_RS09675	COG0126	phosphoglycerate kinase activity
EOJ31_RS09685	COG2390	Transcriptional regulator
EOJ31_RS09705	COG0740	serine-type endopeptidase activity
EOJ31_RS09715	COG1481	regulation of sporulation
EOJ31_RS09720	COG0391	Required for morphogenesis under gluconeogenic growth conditions
EOJ31_RS09725	COG1660	Displays ATPase and GTPase activities
EOJ31_RS09730	COG0492	ferredoxin-NADP+ reductase activity
EOJ31_RS09745	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
EOJ31_RS09755	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EOJ31_RS09760	COG0556	nucleotide-excision repair
EOJ31_RS09775	COG1388	LysM domain
EOJ31_RS09775	COG3942	CHAP domain
EOJ31_RS09785	COG0653	protein targeting
EOJ31_RS09790	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
EOJ31_RS09795	COG1040	competence protein
EOJ31_RS09800	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
EOJ31_RS09810	COG1739	Uncharacterized protein family UPF0029
EOJ31_RS09815	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EOJ31_RS09835	COG2195	Cleaves the N-terminal amino acid of tripeptides
EOJ31_RS09840	COG1929	Belongs to the glycerate kinase type-1 family
EOJ31_RS09860	COG0812	UDP-N-acetylmuramate dehydrogenase activity
EOJ31_RS09875	COG4604	ABC transporter, ATP-binding protein
EOJ31_RS09880	COG4605	iron ion homeostasis
EOJ31_RS09885	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EOJ31_RS09890	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EOJ31_RS09895	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EOJ31_RS09900	COG1780	Probably involved in ribonucleotide reductase function
EOJ31_RS09915	COG3104	oligopeptide transport
EOJ31_RS09920	COG1597	lipid kinase activity
EOJ31_RS09930	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
EOJ31_RS09935	COG1174	glycine betaine transport
EOJ31_RS09940	COG1125	glycine betaine transport
EOJ31_RS09940	COG0517	IMP dehydrogenase activity
EOJ31_RS09945	COG0514	ATP-dependent DNA helicase (RecQ)
EOJ31_RS09950	COG0488	(ABC) transporter
EOJ31_RS09960	COG1368	sulfuric ester hydrolase activity
EOJ31_RS09990	COG0512	Glutamine amidotransferase of anthranilate synthase
EOJ31_RS09990	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EOJ31_RS09995	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
EOJ31_RS10000	COG0720	synthase
EOJ31_RS10005	COG0602	queuosine metabolic process
EOJ31_RS10015	COG0463	Glycosyl transferase, family 2
EOJ31_RS10020	COG0656	L-ascorbic acid biosynthetic process
EOJ31_RS10025	COG1253	flavin adenine dinucleotide binding
EOJ31_RS10030	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
EOJ31_RS10035	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EOJ31_RS10035	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EOJ31_RS10035	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EOJ31_RS10040	COG1105	Belongs to the carbohydrate kinase PfkB family
EOJ31_RS10045	COG1349	DNA-binding transcription factor activity
EOJ31_RS10050	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
EOJ31_RS10075	COG0415	Belongs to the DNA photolyase family
EOJ31_RS10080	COG0471	metal ion transport
EOJ31_RS10085	COG0039	L-malate dehydrogenase activity
EOJ31_RS10095	COG4989	oxidoreductase activity
EOJ31_RS10100	COG0523	cobalamin synthesis protein
EOJ31_RS10110	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
EOJ31_RS10115	COG4988	ABC transporter
EOJ31_RS10120	COG1968	undecaprenyl-diphosphatase activity
EOJ31_RS10130	COG1671	Belongs to the UPF0178 family
EOJ31_RS10135	COG1611	Belongs to the LOG family
EOJ31_RS10150	COG1959	2 iron, 2 sulfur cluster binding
EOJ31_RS10160	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EOJ31_RS10185	COG2839	Protein conserved in bacteria
EOJ31_RS10190	COG2814	Major facilitator Superfamily
EOJ31_RS10195	COG0583	DNA-binding transcription factor activity
EOJ31_RS10210	COG0217	transcriptional regulatory protein
EOJ31_RS10220	COG0662	Cupin 2, conserved barrel domain protein
EOJ31_RS10220	COG2207	Transcriptional regulator
EOJ31_RS10230	COG3942	CHAP domain
EOJ31_RS10230	COG1388	LysM domain
EOJ31_RS10240	COG0306	phosphate transporter
EOJ31_RS10245	COG1392	Phosphate transport regulator
EOJ31_RS10255	COG0577	efflux transmembrane transporter activity
EOJ31_RS10260	COG1136	(ABC) transporter
EOJ31_RS10265	COG2205	protein histidine kinase activity
EOJ31_RS10275	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EOJ31_RS10285	COG0657	acetylesterase activity
EOJ31_RS10290	COG3949	Membrane
EOJ31_RS10300	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
EOJ31_RS10310	COG2376	Dihydroxyacetone kinase
EOJ31_RS10315	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EOJ31_RS10320	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EOJ31_RS10325	COG1120	ATPase activity
EOJ31_RS10330	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EOJ31_RS10335	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EOJ31_RS10340	COG1132	(ABC) transporter
EOJ31_RS10345	COG1686	Belongs to the peptidase S11 family
EOJ31_RS10350	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
EOJ31_RS10360	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
EOJ31_RS10365	COG1682	transport, permease protein
EOJ31_RS10370	COG1134	teichoic acid transport
EOJ31_RS10375	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
EOJ31_RS10390	COG1121	(ABC) transporter
EOJ31_RS10395	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EOJ31_RS10400	COG0803	Belongs to the bacterial solute-binding protein 9 family
EOJ31_RS10410	COG1320	monovalent cation:proton antiporter activity
EOJ31_RS10420	COG1863	multisubunit Na H antiporter MnhE subunit
EOJ31_RS10425	COG0651	ATP synthesis coupled electron transport
EOJ31_RS10430	COG1006	Multisubunit Na H antiporter MnhC subunit
EOJ31_RS10435	COG2111	Na H antiporter
EOJ31_RS10440	COG2111	Na H antiporter
EOJ31_RS10440	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EOJ31_RS10475	COG2267	carboxylic ester hydrolase activity
EOJ31_RS10495	COG0546	phosphoglycolate phosphatase activity
EOJ31_RS10500	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EOJ31_RS10505	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EOJ31_RS10520	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
EOJ31_RS10525	COG0018	arginyl-trna synthetase
EOJ31_RS10550	COG1078	dGTPase activity
EOJ31_RS10560	COG0655	NAD(P)H dehydrogenase (quinone) activity
EOJ31_RS10565	COG0667	Aldo Keto reductase
EOJ31_RS10570	COG4844	belongs to the
EOJ31_RS10585	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
EOJ31_RS10590	COG0095	Lipoate-protein ligase
EOJ31_RS10595	COG0280	phosphate acetyltransferase
EOJ31_RS10600	COG3253	May function as heme-dependent peroxidase
EOJ31_RS10620	COG2363	Small membrane protein
EOJ31_RS10635	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
EOJ31_RS10660	COG0477	Major facilitator Superfamily
EOJ31_RS10675	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
EOJ31_RS10680	COG0363	glucosamine-6-phosphate deaminase activity
EOJ31_RS10690	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EOJ31_RS10695	COG1469	GTP cyclohydrolase I activity
EOJ31_RS10700	COG2271	Major facilitator Superfamily
EOJ31_RS10725	COG0431	NADPH-dependent FMN reductase
EOJ31_RS10730	COG0561	phosphatase activity
EOJ31_RS10740	COG1428	Deoxynucleoside kinase
EOJ31_RS10745	COG1428	Deoxynucleoside kinase
EOJ31_RS10750	COG0546	phosphoglycolate phosphatase activity
EOJ31_RS10755	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EOJ31_RS10765	COG0737	Belongs to the 5'-nucleotidase family
EOJ31_RS10780	COG1063	alcohol dehydrogenase
EOJ31_RS10785	COG2814	Major facilitator Superfamily
EOJ31_RS10790	COG1349	DNA-binding transcription factor activity
EOJ31_RS10815	COG1473	amidohydrolase
EOJ31_RS10820	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
EOJ31_RS10825	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
EOJ31_RS10830	COG0049	tRNA binding
EOJ31_RS10835	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
EOJ31_RS10845	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EOJ31_RS10850	COG0085	RNA polymerase activity
EOJ31_RS10855	COG2813	Specifically methylates the guanine in position
EOJ31_RS10860	COG0222	ribosome binding
EOJ31_RS10865	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
EOJ31_RS10870	COG0081	regulation of translation
EOJ31_RS10875	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
EOJ31_RS10880	COG0250	Participates in transcription elongation, termination and antitermination
EOJ31_RS10890	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EOJ31_RS10900	COG3688	RNA-binding protein containing a PIN domain
EOJ31_RS10910	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
EOJ31_RS10915	COG0215	cysteine-tRNA ligase activity
EOJ31_RS10925	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EOJ31_RS10930	COG4956	integral membrane protein (PIN domain superfamily)
EOJ31_RS10935	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
EOJ31_RS10940	COG0542	response to heat
EOJ31_RS10945	COG3869	Catalyzes the specific phosphorylation of arginine residues in
EOJ31_RS10950	COG3880	PFAM UvrB UvrC protein
EOJ31_RS10960	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EOJ31_RS10965	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
EOJ31_RS10970	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
EOJ31_RS10975	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EOJ31_RS11060	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
EOJ31_RS11065	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
EOJ31_RS11070	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
EOJ31_RS11090	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EOJ31_RS11105	COG1098	S1 RNA binding domain
EOJ31_RS11115	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
EOJ31_RS11120	COG3956	TIGRFAM MazG family protein
EOJ31_RS11125	COG2244	polysaccharide biosynthetic process
EOJ31_RS11130	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
EOJ31_RS11135	COG0193	aminoacyl-tRNA hydrolase activity
EOJ31_RS11140	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
EOJ31_RS11145	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EOJ31_RS11150	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
EOJ31_RS11155	COG2088	sporulation resulting in formation of a cellular spore
EOJ31_RS11160	COG0251	oxidation-reduction process
EOJ31_RS11165	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EOJ31_RS11170	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
EOJ31_RS11175	COG4466	Protein conserved in bacteria
EOJ31_RS11180	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
EOJ31_RS11185	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
EOJ31_RS11190	COG0084	hydrolase, TatD family'
EOJ31_RS11195	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EOJ31_RS11195	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EOJ31_RS11200	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
EOJ31_RS11205	COG2827	Endonuclease containing a URI domain
EOJ31_RS11210	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
EOJ31_RS11215	COG4467	Involved in initiation control of chromosome replication
EOJ31_RS11220	COG1774	PSP1 C-terminal conserved region
EOJ31_RS11225	COG0470	DNA polymerase III
EOJ31_RS11230	COG3870	Protein conserved in bacteria
EOJ31_RS11240	COG1982	Orn Lys Arg decarboxylase major
EOJ31_RS11245	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EOJ31_RS11265	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
EOJ31_RS11270	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
EOJ31_RS11275	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
EOJ31_RS11290	COG2188	Transcriptional regulator
EOJ31_RS11295	COG0366	Alpha amylase catalytic
EOJ31_RS11300	COG1263	PTS System
EOJ31_RS11300	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EOJ31_RS11310	COG0493	'glutamate synthase
EOJ31_RS11315	COG0069	glutamate synthase activity
EOJ31_RS11315	COG0067	glutamate synthase
EOJ31_RS11315	COG0070	glutamate synthase
EOJ31_RS11335	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EOJ31_RS11340	COG0494	nUDIX hydrolase
EOJ31_RS11350	COG0438	transferase activity, transferring glycosyl groups
EOJ31_RS11365	COG1278	Cold shock
EOJ31_RS11370	COG3759	membrane
EOJ31_RS11395	COG1846	Transcriptional regulator
EOJ31_RS11400	COG0626	cystathionine gamma-synthase activity
EOJ31_RS11405	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EOJ31_RS11420	COG1279	arginine transmembrane transporter activity
EOJ31_RS11425	COG0733	neurotransmitter:sodium symporter activity
EOJ31_RS11435	COG1647	Serine aminopeptidase, S33
EOJ31_RS11440	COG0671	phosphoesterase, PA-phosphatase related
EOJ31_RS11455	COG5609	conserved protein (DUF2294)
EOJ31_RS11460	COG3002	Belongs to the UPF0753 family
EOJ31_RS11465	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EOJ31_RS11480	COG0523	cobalamin synthesis protein
EOJ31_RS11490	COG0518	GMP synthase (glutamine-hydrolyzing) activity
EOJ31_RS11490	COG0519	Catalyzes the synthesis of GMP from XMP
EOJ31_RS11495	COG0516	GMP reductase activity
EOJ31_RS11495	COG0517	IMP dehydrogenase activity
EOJ31_RS11500	COG2233	PERMEase
EOJ31_RS11505	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EOJ31_RS11520	COG5183	chlorophyll binding
EOJ31_RS11525	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
EOJ31_RS11530	COG1823	symporter activity
EOJ31_RS11535	COG0778	Nitroreductase
EOJ31_RS11540	COG0450	alkyl hydroperoxide reductase
EOJ31_RS11545	COG3634	alkyl hydroperoxide reductase activity
EOJ31_RS11570	COG1280	lysine exporter protein (LysE YggA)
EOJ31_RS11600	COG3728	DNA packaging
EOJ31_RS11600	COG5484	DNA packaging
EOJ31_RS11685	COG0582	viral genome integration into host DNA
EOJ31_RS11690	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
EOJ31_RS11700	COG0360	Binds together with S18 to 16S ribosomal RNA
EOJ31_RS11715	COG0012	GTP binding
EOJ31_RS11720	COG4481	Protein conserved in bacteria
EOJ31_RS11725	COG0668	transmembrane transport
EOJ31_RS11730	COG1475	DNA binding
EOJ31_RS11735	COG0626	cystathionine gamma-synthase activity
EOJ31_RS11740	COG0626	cystathionine gamma-synthase activity
EOJ31_RS11745	COG0646	methionine synthase
EOJ31_RS11745	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
EOJ31_RS11750	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
EOJ31_RS11770	COG3942	CHAP domain
EOJ31_RS11785	COG0183	Belongs to the thiolase family
EOJ31_RS11790	COG3250	beta-galactosidase activity
EOJ31_RS11795	COG1028	Short-chain dehydrogenase reductase Sdr
EOJ31_RS11800	COG1312	Catalyzes the dehydration of D-mannonate
EOJ31_RS11805	COG1904	glucuronate isomerase
EOJ31_RS11810	COG2211	Major facilitator Superfamily
EOJ31_RS11815	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EOJ31_RS11820	COG0800	Aldolase
EOJ31_RS11825	COG2207	Transcriptional regulator
EOJ31_RS11870	COG1476	TRANSCRIPTIONal
EOJ31_RS11880	COG1131	(ABC) transporter
EOJ31_RS11900	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EOJ31_RS11920	COG1136	(ABC) transporter
EOJ31_RS11925	COG0577	efflux transmembrane transporter activity
EOJ31_RS12005	COG2348	transferase activity, transferring amino-acyl groups
EOJ31_RS12015	COG1063	alcohol dehydrogenase
EOJ31_RS12020	COG0577	efflux transmembrane transporter activity
EOJ31_RS12025	COG1136	(ABC) transporter
EOJ31_RS12065	COG1475	DNA binding
EOJ31_RS12070	COG0357	Ribosomal RNA small subunit methyltransferase G
EOJ31_RS12075	COG0445	tRNA wobble uridine modification
EOJ31_RS12080	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
EOJ31_RS12085	COG0594	ribonuclease P activity
EOJ31_RS12095	COG5658	integral membrane protein
EOJ31_RS12100	COG2348	transferase activity, transferring amino-acyl groups
EOJ31_RS12125	COG1192	Involved in chromosome partitioning
EOJ31_RS12135	COG1002	Type II restriction enzyme, methylase subunits
EOJ31_RS12155	COG1733	regulation of RNA biosynthetic process
EOJ31_RS12165	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
EOJ31_RS12200	COG1937	Protein conserved in bacteria
EOJ31_RS12205	COG2217	Heavy metal translocating P-type atpase
EOJ31_RS12375	COG1674	ftsk spoiiie
EOJ31_RS12415	COG1674	ftsk spoiiie
EOJ31_RS12450	COG1674	ftsk spoiiie