locus-tag	class	description
EYQ96_RS00005	COG2130	NADP-dependent
EYQ96_RS00010	COG0702	epimerase
EYQ96_RS00020	COG0789	Transcriptional regulator
EYQ96_RS00025	COG0366	Alpha amylase catalytic
EYQ96_RS00030	COG4716	Myosin-crossreactive antigen
EYQ96_RS00055	COG0583	DNA-binding transcription factor activity
EYQ96_RS00075	COG0492	ferredoxin-NADP+ reductase activity
EYQ96_RS00085	COG3118	belongs to the thioredoxin family
EYQ96_RS00115	COG1695	Transcriptional regulator
EYQ96_RS00120	COG1132	(ABC) transporter
EYQ96_RS00155	COG2814	Major facilitator Superfamily
EYQ96_RS00170	COG1846	Transcriptional regulator
EYQ96_RS00175	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EYQ96_RS00185	COG0579	oxidoreductase
EYQ96_RS00190	COG1620	l-lactate permease
EYQ96_RS00195	COG3527	Alpha-acetolactate decarboxylase
EYQ96_RS00200	COG0028	Belongs to the TPP enzyme family
EYQ96_RS00220	COG3189	MarR family transcriptional regulator
EYQ96_RS00280	COG2217	Heavy metal translocating P-type atpase
EYQ96_RS00285	COG1937	Protein conserved in bacteria
EYQ96_RS00295	COG1230	cation diffusion facilitator family transporter
EYQ96_RS00380	COG3682	Transcriptional regulator
EYQ96_RS00400	COG1131	(ABC) transporter
EYQ96_RS00415	COG1192	Involved in chromosome partitioning
EYQ96_RS00530	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
EYQ96_RS00535	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
EYQ96_RS00540	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
EYQ96_RS00560	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EYQ96_RS00575	COG1098	S1 RNA binding domain
EYQ96_RS00585	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
EYQ96_RS00590	COG3956	TIGRFAM MazG family protein
EYQ96_RS00595	COG2244	polysaccharide biosynthetic process
EYQ96_RS00600	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
EYQ96_RS00605	COG0193	aminoacyl-tRNA hydrolase activity
EYQ96_RS00610	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
EYQ96_RS00615	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EYQ96_RS00620	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
EYQ96_RS00625	COG2088	sporulation resulting in formation of a cellular spore
EYQ96_RS00630	COG0251	oxidation-reduction process
EYQ96_RS00635	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EYQ96_RS00640	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
EYQ96_RS00645	COG4466	Protein conserved in bacteria
EYQ96_RS00650	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
EYQ96_RS00655	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
EYQ96_RS00660	COG0084	hydrolase, TatD family'
EYQ96_RS00665	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EYQ96_RS00665	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EYQ96_RS00670	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
EYQ96_RS00675	COG2827	Endonuclease containing a URI domain
EYQ96_RS00680	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
EYQ96_RS00685	COG4467	Involved in initiation control of chromosome replication
EYQ96_RS00690	COG1774	PSP1 C-terminal conserved region
EYQ96_RS00695	COG0470	DNA polymerase III
EYQ96_RS00700	COG3870	Protein conserved in bacteria
EYQ96_RS00710	COG1982	Orn Lys Arg decarboxylase major
EYQ96_RS00715	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EYQ96_RS00735	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
EYQ96_RS00745	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
EYQ96_RS00760	COG2188	Transcriptional regulator
EYQ96_RS00765	COG0366	Alpha amylase catalytic
EYQ96_RS00770	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EYQ96_RS00770	COG1263	PTS System
EYQ96_RS00780	COG0493	'glutamate synthase
EYQ96_RS00785	COG0070	glutamate synthase
EYQ96_RS00785	COG0067	glutamate synthase
EYQ96_RS00785	COG0069	glutamate synthase activity
EYQ96_RS00805	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EYQ96_RS00810	COG0494	nUDIX hydrolase
EYQ96_RS00820	COG0438	transferase activity, transferring glycosyl groups
EYQ96_RS00825	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EYQ96_RS00835	COG1278	Cold shock
EYQ96_RS00840	COG3759	membrane
EYQ96_RS00870	COG1846	Transcriptional regulator
EYQ96_RS00875	COG0626	cystathionine gamma-synthase activity
EYQ96_RS00880	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EYQ96_RS00895	COG1279	arginine transmembrane transporter activity
EYQ96_RS00900	COG0733	neurotransmitter:sodium symporter activity
EYQ96_RS00910	COG1647	Serine aminopeptidase, S33
EYQ96_RS00915	COG0671	phosphoesterase, PA-phosphatase related
EYQ96_RS00930	COG5609	conserved protein (DUF2294)
EYQ96_RS00935	COG3002	Belongs to the UPF0753 family
EYQ96_RS00940	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EYQ96_RS00955	COG0523	cobalamin synthesis protein
EYQ96_RS00965	COG0519	Catalyzes the synthesis of GMP from XMP
EYQ96_RS00965	COG0518	GMP synthase (glutamine-hydrolyzing) activity
EYQ96_RS00970	COG0517	IMP dehydrogenase activity
EYQ96_RS00970	COG0516	GMP reductase activity
EYQ96_RS00975	COG2233	PERMEase
EYQ96_RS00980	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EYQ96_RS00995	COG5183	chlorophyll binding
EYQ96_RS01000	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
EYQ96_RS01005	COG1823	symporter activity
EYQ96_RS01010	COG0778	Nitroreductase
EYQ96_RS01015	COG0450	alkyl hydroperoxide reductase
EYQ96_RS01020	COG3634	alkyl hydroperoxide reductase activity
EYQ96_RS01045	COG1280	lysine exporter protein (LysE YggA)
EYQ96_RS01065	COG3728	DNA packaging
EYQ96_RS01065	COG5484	DNA packaging
EYQ96_RS01135	COG0582	viral genome integration into host DNA
EYQ96_RS01150	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
EYQ96_RS01160	COG0360	Binds together with S18 to 16S ribosomal RNA
EYQ96_RS01175	COG0012	GTP binding
EYQ96_RS01180	COG4481	Protein conserved in bacteria
EYQ96_RS01185	COG0668	transmembrane transport
EYQ96_RS01190	COG1475	DNA binding
EYQ96_RS01195	COG0626	cystathionine gamma-synthase activity
EYQ96_RS01200	COG0626	cystathionine gamma-synthase activity
EYQ96_RS01205	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
EYQ96_RS01205	COG0646	methionine synthase
EYQ96_RS01210	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
EYQ96_RS01235	COG1309	transcriptional regulator
EYQ96_RS01245	COG3942	CHAP domain
EYQ96_RS01250	COG0640	Transcriptional regulator
EYQ96_RS01255	COG2814	Major facilitator Superfamily
EYQ96_RS01270	COG0210	DNA helicase
EYQ96_RS01285	COG0183	Belongs to the thiolase family
EYQ96_RS01315	COG1476	TRANSCRIPTIONal
EYQ96_RS01325	COG1131	(ABC) transporter
EYQ96_RS01340	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EYQ96_RS01360	COG1136	(ABC) transporter
EYQ96_RS01365	COG0577	efflux transmembrane transporter activity
EYQ96_RS01420	COG1682	transport, permease protein
EYQ96_RS01435	COG2348	transferase activity, transferring amino-acyl groups
EYQ96_RS01445	COG1063	alcohol dehydrogenase
EYQ96_RS01460	COG1073	alpha beta
EYQ96_RS01490	COG1136	(ABC) transporter
EYQ96_RS01530	COG1475	DNA binding
EYQ96_RS01535	COG0357	Ribosomal RNA small subunit methyltransferase G
EYQ96_RS01540	COG0445	tRNA wobble uridine modification
EYQ96_RS01545	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
EYQ96_RS01550	COG0594	ribonuclease P activity
EYQ96_RS01560	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
EYQ96_RS01565	COG0592	DNA-directed DNA polymerase activity
EYQ96_RS01570	COG2501	S4 domain
EYQ96_RS01575	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
EYQ96_RS01580	COG0187	DNA topoisomerase II activity
EYQ96_RS01585	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EYQ96_RS01590	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
EYQ96_RS01605	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
EYQ96_RS01615	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EYQ96_RS01625	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
EYQ96_RS01630	COG0359	binds to the 23S rRNA
EYQ96_RS01635	COG0305	Participates in initiation and elongation during chromosome replication
EYQ96_RS01655	COG0745	RESPONSE REGULATOR receiver
EYQ96_RS01660	COG5002	protein histidine kinase activity
EYQ96_RS01665	COG4863	YycH protein
EYQ96_RS01675	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
EYQ96_RS01705	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
EYQ96_RS01715	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
EYQ96_RS01725	COG0464	growth
EYQ96_RS01750	COG3223	Belongs to the PsiE family
EYQ96_RS01795	COG2851	Citrate transporter
EYQ96_RS01800	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
EYQ96_RS01805	COG0300	oxidoreductase activity
EYQ96_RS01810	COG2814	Major facilitator Superfamily
EYQ96_RS01815	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EYQ96_RS01820	COG2226	methyltransferase
EYQ96_RS01845	COG2808	Putative FMN-binding domain
EYQ96_RS01850	COG0110	maltose O-acetyltransferase activity
EYQ96_RS01855	COG0656	L-ascorbic acid biosynthetic process
EYQ96_RS01865	COG0789	Transcriptional regulator
EYQ96_RS01870	COG0025	NhaP-type Na H and K H
EYQ96_RS01880	COG0583	DNA-binding transcription factor activity
EYQ96_RS01885	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EYQ96_RS01895	COG0583	DNA-binding transcription factor activity
EYQ96_RS01900	COG0110	maltose O-acetyltransferase activity
EYQ96_RS01910	COG1114	Component of the transport system for branched-chain amino acids
EYQ96_RS01915	COG2814	Major facilitator Superfamily
EYQ96_RS01970	COG1609	Transcriptional regulator
EYQ96_RS01980	COG1869	D-ribose catabolic process
EYQ96_RS01990	COG0604	alcohol dehydrogenase
EYQ96_RS02005	COG2814	Major facilitator Superfamily
EYQ96_RS02025	COG1131	(ABC) transporter
EYQ96_RS02055	COG0601	transmembrane transport
EYQ96_RS02065	COG0444	Belongs to the ABC transporter superfamily
EYQ96_RS02070	COG1124	(ABC) transporter
EYQ96_RS02085	COG0346	lactoylglutathione lyase activity
EYQ96_RS02095	COG1518	maintenance of DNA repeat elements
EYQ96_RS02120	COG3711	transcriptional antiterminator
EYQ96_RS02120	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EYQ96_RS02125	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EYQ96_RS02125	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EYQ96_RS02125	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EYQ96_RS02130	COG1482	cell wall glycoprotein biosynthetic process
EYQ96_RS02135	COG0706	membrane insertase activity
EYQ96_RS02160	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EYQ96_RS02180	COG2235	arginine
EYQ96_RS02185	COG1438	arginine binding
EYQ96_RS02190	COG0659	secondary active sulfate transmembrane transporter activity
EYQ96_RS02215	COG0438	transferase activity, transferring glycosyl groups
EYQ96_RS02220	COG0653	protein targeting
EYQ96_RS02230	COG1073	alpha beta
EYQ96_RS02240	COG0201	protein transport
EYQ96_RS02255	COG0747	negative chemotaxis
EYQ96_RS02260	COG0601	transmembrane transport
EYQ96_RS02265	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EYQ96_RS02275	COG1124	(ABC) transporter
EYQ96_RS02280	COG0789	Transcriptional regulator
EYQ96_RS02285	COG0656	L-ascorbic acid biosynthetic process
EYQ96_RS02290	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EYQ96_RS02305	COG2259	Doxx family
EYQ96_RS02315	COG1959	2 iron, 2 sulfur cluster binding
EYQ96_RS02320	COG2910	NAD(P)H-binding
EYQ96_RS02325	COG1876	peptidase activity
EYQ96_RS02330	COG1882	Formate acetyltransferase
EYQ96_RS02335	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
EYQ96_RS02345	COG1288	antiporter activity
EYQ96_RS02350	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EYQ96_RS02370	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
EYQ96_RS02455	COG0745	RESPONSE REGULATOR receiver
EYQ96_RS02460	COG1131	(ABC) transporter
EYQ96_RS02470	COG2205	protein histidine kinase activity
EYQ96_RS02480	COG1136	(ABC) transporter
EYQ96_RS02495	COG4221	oxidoreductase activity
EYQ96_RS02500	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
EYQ96_RS02505	COG3478	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
EYQ96_RS02510	COG2962	Rard protein
EYQ96_RS02515	COG0471	metal ion transport
EYQ96_RS02525	COG1695	Transcriptional regulator
EYQ96_RS02540	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
EYQ96_RS02570	COG1288	antiporter activity
EYQ96_RS02605	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
EYQ96_RS02625	COG2814	Major facilitator Superfamily
EYQ96_RS02630	COG0737	Belongs to the 5'-nucleotidase family
EYQ96_RS02700	COG0477	Major facilitator Superfamily
EYQ96_RS02705	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EYQ96_RS02725	COG2113	Glycine betaine
EYQ96_RS02730	COG2409	Drug exporters of the RND superfamily
EYQ96_RS02740	COG1764	response to oxidative stress
EYQ96_RS02750	COG3942	CHAP domain
EYQ96_RS02750	COG1705	Flagellar rod assembly protein muramidase FlgJ
EYQ96_RS02770	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EYQ96_RS02780	COG0739	heme binding
EYQ96_RS02785	COG3227	Zinc metalloprotease (Elastase)
EYQ96_RS02790	COG2843	Capsule synthesis protein
EYQ96_RS02805	COG3961	Belongs to the TPP enzyme family
EYQ96_RS02815	COG4195	phage-related replication protein
EYQ96_RS02825	COG1785	Belongs to the alkaline phosphatase family
EYQ96_RS02835	COG0745	RESPONSE REGULATOR receiver
EYQ96_RS02840	COG2205	protein histidine kinase activity
EYQ96_RS02845	COG1136	(ABC) transporter
EYQ96_RS02875	COG0175	sulfate reduction
EYQ96_RS02880	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
EYQ96_RS02885	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EYQ96_RS02900	COG0730	response to heat
EYQ96_RS02905	COG2046	Belongs to the sulfate adenylyltransferase family
EYQ96_RS02910	COG0529	Catalyzes the synthesis of activated sulfate
EYQ96_RS02920	COG3942	CHAP domain
EYQ96_RS02925	COG1328	CTP reductase activity
EYQ96_RS02930	COG0602	queuosine metabolic process
EYQ96_RS02935	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
EYQ96_RS02945	COG1510	regulation of RNA biosynthetic process
EYQ96_RS02950	COG1012	belongs to the aldehyde dehydrogenase family
EYQ96_RS02955	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
EYQ96_RS02960	COG1473	amidohydrolase
EYQ96_RS02980	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EYQ96_RS02985	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EYQ96_RS02985	COG0574	Belongs to the PEP-utilizing enzyme family
EYQ96_RS02990	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
EYQ96_RS02995	COG0579	oxidoreductase
EYQ96_RS03005	COG2190	(PTS) system
EYQ96_RS03005	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EYQ96_RS03005	COG1263	PTS System
EYQ96_RS03010	COG2723	6-phospho-beta-galactosidase activity
EYQ96_RS03020	COG1695	Transcriptional regulator
EYQ96_RS03025	COG3588	fructose-bisphosphate aldolase
EYQ96_RS03030	COG0563	adenylate kinase activity
EYQ96_RS03040	COG0446	pyridine nucleotide-disulphide oxidoreductase
EYQ96_RS03060	COG0531	amino acid
EYQ96_RS03070	COG0583	DNA-binding transcription factor activity
EYQ96_RS03075	COG0039	L-malate dehydrogenase activity
EYQ96_RS03080	COG0028	Belongs to the TPP enzyme family
EYQ96_RS03085	COG3527	Alpha-acetolactate decarboxylase
EYQ96_RS03095	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
EYQ96_RS03100	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
EYQ96_RS03115	COG4640	response to antibiotic
EYQ96_RS03145	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
EYQ96_RS03155	COG0167	dihydroorotate dehydrogenase activity
EYQ96_RS03160	COG3001	Fructosamine kinase
EYQ96_RS03170	COG0596	Alpha beta hydrolase
EYQ96_RS03180	COG4221	oxidoreductase activity
EYQ96_RS03235	COG0741	lytic transglycosylase activity
EYQ96_RS03250	COG0436	Aminotransferase
EYQ96_RS03260	COG2608	mercury ion transmembrane transporter activity
EYQ96_RS03275	COG1028	Short-chain dehydrogenase reductase Sdr
EYQ96_RS03285	COG1012	belongs to the aldehyde dehydrogenase family
EYQ96_RS03315	COG0598	Magnesium transport protein CorA
EYQ96_RS03325	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EYQ96_RS03330	COG3425	synthase
EYQ96_RS03340	COG1388	LysM domain
EYQ96_RS03340	COG3942	CHAP domain
EYQ96_RS03355	COG1380	Effector of murein hydrolase LrgA
EYQ96_RS03360	COG1346	cytolysis
EYQ96_RS03365	COG0028	Belongs to the TPP enzyme family
EYQ96_RS03390	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EYQ96_RS03395	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EYQ96_RS03400	COG0657	acetylesterase activity
EYQ96_RS03410	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
EYQ96_RS03420	COG2843	Capsule synthesis protein
EYQ96_RS03440	COG1070	Carbohydrate kinase
EYQ96_RS03450	COG1760	l-serine dehydratase
EYQ96_RS03455	COG1760	l-serine dehydratase
EYQ96_RS03470	COG3764	Sortase (surface protein transpeptidase)
EYQ96_RS03480	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EYQ96_RS03485	COG0778	Nitroreductase
EYQ96_RS03490	COG1012	belongs to the aldehyde dehydrogenase family
EYQ96_RS03510	COG2314	TM2 domain
EYQ96_RS03515	COG2514	catechol 2,3-dioxygenase activity
EYQ96_RS03530	COG0583	DNA-binding transcription factor activity
EYQ96_RS03535	COG1012	belongs to the aldehyde dehydrogenase family
EYQ96_RS03540	COG3949	Membrane
EYQ96_RS03550	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
EYQ96_RS03555	COG0586	Pfam SNARE associated Golgi protein
EYQ96_RS03560	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EYQ96_RS03565	COG2022	thiamine diphosphate biosynthetic process
EYQ96_RS03575	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EYQ96_RS03580	COG0352	thiamine-phosphate diphosphorylase activity
EYQ96_RS03585	COG2271	Major facilitator Superfamily
EYQ96_RS03590	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
EYQ96_RS03600	COG4876	unkown
EYQ96_RS03605	COG2357	RelA SpoT domain protein
EYQ96_RS03620	COG1802	Transcriptional regulator
EYQ96_RS03625	COG1070	Carbohydrate kinase
EYQ96_RS03635	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EYQ96_RS03650	COG1215	transferase activity, transferring glycosyl groups
EYQ96_RS03655	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EYQ96_RS03660	COG0494	nUDIX hydrolase
EYQ96_RS03670	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EYQ96_RS03675	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EYQ96_RS03680	COG0022	dehydrogenase e1 component
EYQ96_RS03685	COG0508	dehydrogenase complex catalyzes the overall conversion of
EYQ96_RS03715	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EYQ96_RS03720	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
EYQ96_RS03730	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
EYQ96_RS03735	COG1028	Short-chain dehydrogenase reductase Sdr
EYQ96_RS03740	COG1363	Peptidase, m42
EYQ96_RS03745	COG4808	Protein conserved in bacteria
EYQ96_RS03750	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EYQ96_RS03765	COG0069	glutamate synthase activity
EYQ96_RS03775	COG1266	CAAX protease self-immunity
EYQ96_RS03780	COG4619	ABC transporter
EYQ96_RS03785	COG0390	transport system, permease component
EYQ96_RS03790	COG2205	protein histidine kinase activity
EYQ96_RS03795	COG0745	RESPONSE REGULATOR receiver
EYQ96_RS03805	COG2814	Major facilitator Superfamily
EYQ96_RS03810	COG2272	Belongs to the type-B carboxylesterase lipase family
EYQ96_RS03815	COG0531	amino acid
EYQ96_RS03820	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
EYQ96_RS03845	COG1174	glycine betaine transport
EYQ96_RS03850	COG1346	cytolysis
EYQ96_RS03855	COG1380	Effector of murein hydrolase LrgA
EYQ96_RS03865	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EYQ96_RS03875	COG3477	response to acidic pH
EYQ96_RS03885	COG0706	membrane insertase activity
EYQ96_RS03895	COG0531	amino acid
EYQ96_RS03900	COG0025	NhaP-type Na H and K H
EYQ96_RS03905	COG1113	amino acid transport
EYQ96_RS03925	COG2814	Major facilitator Superfamily
EYQ96_RS03935	COG1929	Belongs to the glycerate kinase type-1 family
EYQ96_RS03950	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EYQ96_RS03955	COG0741	lytic transglycosylase activity
EYQ96_RS03960	COG0588	phosphoglycerate mutase activity
EYQ96_RS03970	COG2814	Major facilitator Superfamily
EYQ96_RS03975	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EYQ96_RS03980	COG0765	amino acid transport
EYQ96_RS03985	COG1126	abc transporter atp-binding protein
EYQ96_RS03990	COG2348	transferase activity, transferring amino-acyl groups
EYQ96_RS04005	COG0803	Belongs to the bacterial solute-binding protein 9 family
EYQ96_RS04025	COG0454	-acetyltransferase
EYQ96_RS04030	COG0747	negative chemotaxis
EYQ96_RS04040	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EYQ96_RS04045	COG2146	nitrite reductase [NAD(P)H] activity
EYQ96_RS04055	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
EYQ96_RS04060	COG1140	nitrate reductase beta subunit
EYQ96_RS04080	COG4585	Histidine kinase
EYQ96_RS04090	COG2223	nitrite transmembrane transporter activity
EYQ96_RS04105	COG0778	Nitroreductase
EYQ96_RS04140	COG1263	PTS System
EYQ96_RS04140	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EYQ96_RS04155	COG1511	domain protein
EYQ96_RS04165	COG1028	Short-chain dehydrogenase reductase Sdr
EYQ96_RS04170	COG2610	gluconate transmembrane transporter activity
EYQ96_RS04175	COG0583	DNA-binding transcription factor activity
EYQ96_RS04185	COG1028	Short-chain dehydrogenase reductase Sdr
EYQ96_RS04215	COG0492	ferredoxin-NADP+ reductase activity
EYQ96_RS04220	COG0456	acetyltransferase
EYQ96_RS04225	COG0604	alcohol dehydrogenase
EYQ96_RS04230	COG2822	iron ion transport
EYQ96_RS04235	COG2837	iron assimilation
EYQ96_RS04240	COG0672	)-iron permease
EYQ96_RS04245	COG0805	protein transport
EYQ96_RS04250	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EYQ96_RS04260	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
EYQ96_RS04260	COG0463	Glycosyl transferase, family 2
EYQ96_RS04270	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
EYQ96_RS04270	COG0463	Glycosyl transferase, family 2
EYQ96_RS04275	COG1620	l-lactate permease
EYQ96_RS04280	COG0438	transferase activity, transferring glycosyl groups
EYQ96_RS04285	COG0579	oxidoreductase
EYQ96_RS04300	COG3850	Histidine kinase
EYQ96_RS04300	COG5002	protein histidine kinase activity
EYQ96_RS04335	COG2814	Major facilitator Superfamily
EYQ96_RS04345	COG1566	PFAM secretion protein HlyD family protein
EYQ96_RS04350	COG2814	Major facilitator Superfamily
EYQ96_RS04375	COG0598	Magnesium transport protein CorA
EYQ96_RS04380	COG1304	FMN binding
EYQ96_RS04385	COG0786	glutamate:sodium symporter activity
EYQ96_RS04390	COG1695	Transcriptional regulator
EYQ96_RS04405	COG2094	Belongs to the DNA glycosylase MPG family
EYQ96_RS04415	COG3620	sequence-specific DNA binding
EYQ96_RS04425	COG1069	ribulokinase activity
EYQ96_RS04430	COG4152	abc transporter atp-binding protein
EYQ96_RS04435	COG1668	transmembrane transport
EYQ96_RS04440	COG1742	UPF0060 membrane protein
EYQ96_RS04445	COG2017	converts alpha-aldose to the beta-anomer
EYQ96_RS04450	COG2258	MOSC domain
EYQ96_RS04455	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
EYQ96_RS04465	COG1266	CAAX protease self-immunity
EYQ96_RS04470	COG0010	Belongs to the arginase family
EYQ96_RS04475	COG0583	DNA-binding transcription factor activity
EYQ96_RS04490	COG0659	secondary active sulfate transmembrane transporter activity
EYQ96_RS04495	COG1473	amidohydrolase
EYQ96_RS04500	COG1028	Short-chain dehydrogenase reductase Sdr
EYQ96_RS04520	COG1737	Transcriptional regulator
EYQ96_RS04525	COG1263	PTS System
EYQ96_RS04525	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EYQ96_RS04535	COG0385	Bile acid
EYQ96_RS04540	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EYQ96_RS04560	COG1113	amino acid transport
EYQ96_RS04570	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EYQ96_RS04570	COG1263	PTS System
EYQ96_RS04575	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
EYQ96_RS04590	COG1266	CAAX protease self-immunity
EYQ96_RS04595	COG1349	DNA-binding transcription factor activity
EYQ96_RS04605	COG1316	TRANSCRIPTIONal
EYQ96_RS04635	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EYQ96_RS04640	COG2076	Multidrug Resistance protein
EYQ96_RS04645	COG2076	Multidrug Resistance protein
EYQ96_RS04650	COG3942	CHAP domain
EYQ96_RS04665	COG1757	Na H antiporter
EYQ96_RS04670	COG3942	CHAP domain
EYQ96_RS04680	COG1846	Transcriptional regulator
EYQ96_RS04695	COG0829	nickel cation binding
EYQ96_RS04710	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
EYQ96_RS04715	COG0804	urea catabolic process
EYQ96_RS04725	COG0831	urea catabolic process
EYQ96_RS04730	COG4413	Urea transporter
EYQ96_RS04735	COG0765	amino acid transport
EYQ96_RS04740	COG0765	amino acid transport
EYQ96_RS04745	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EYQ96_RS04750	COG1126	abc transporter atp-binding protein
EYQ96_RS04755	COG1960	acyl-CoA dehydrogenase activity
EYQ96_RS04770	COG1268	BioY protein
EYQ96_RS04780	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
EYQ96_RS04785	COG0725	ABC transporter, periplasmic molybdate-binding protein
EYQ96_RS04790	COG4149	molybdate abc transporter
EYQ96_RS04800	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EYQ96_RS04805	COG0521	Mo-molybdopterin cofactor biosynthetic process
EYQ96_RS04810	COG0315	cyclic pyranopterin monophosphate synthase activity
EYQ96_RS04820	COG1763	Mo-molybdopterin cofactor biosynthetic process
EYQ96_RS04835	COG0746	molybdenum cofactor guanylyltransferase activity
EYQ96_RS04840	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
EYQ96_RS04850	COG2814	Major facilitator Superfamily
EYQ96_RS04870	COG2348	transferase activity, transferring amino-acyl groups
EYQ96_RS04875	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EYQ96_RS04900	COG4975	Glucose uptake
EYQ96_RS04915	COG2252	PERMEase
EYQ96_RS04930	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
EYQ96_RS04935	COG0088	Forms part of the polypeptide exit tunnel
EYQ96_RS04940	COG0089	rRNA binding
EYQ96_RS04945	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
EYQ96_RS04950	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
EYQ96_RS04955	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
EYQ96_RS04960	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
EYQ96_RS04965	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
EYQ96_RS04975	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
EYQ96_RS04980	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
EYQ96_RS04985	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
EYQ96_RS04995	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
EYQ96_RS05000	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
EYQ96_RS05005	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
EYQ96_RS05010	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
EYQ96_RS05015	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
EYQ96_RS05020	COG1841	ribosomal large subunit assembly
EYQ96_RS05030	COG0201	protein transport
EYQ96_RS05035	COG0563	adenylate kinase activity
EYQ96_RS05040	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
EYQ96_RS05050	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
EYQ96_RS05055	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
EYQ96_RS05060	COG0202	RNA polymerase activity
EYQ96_RS05075	COG1122	ATPase activity
EYQ96_RS05085	COG0101	tRNA pseudouridine synthase activity
EYQ96_RS05090	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
EYQ96_RS05120	COG0698	ribose 5-phosphate isomerase
EYQ96_RS05160	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EYQ96_RS05165	COG2130	NADP-dependent
EYQ96_RS05170	COG0604	alcohol dehydrogenase
EYQ96_RS05185	COG1302	Protein conserved in bacteria
EYQ96_RS05195	COG2814	Major facilitator Superfamily
EYQ96_RS05200	COG4264	IucA IucC family
EYQ96_RS05205	COG3457	Alanine racemase
EYQ96_RS05210	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
EYQ96_RS05215	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EYQ96_RS05220	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EYQ96_RS05230	COG2329	Antibiotic biosynthesis monooxygenase
EYQ96_RS05240	COG1988	membrane-bound metal-dependent
EYQ96_RS05245	COG4284	Utp--glucose-1-phosphate uridylyltransferase
EYQ96_RS05250	COG1272	protein, Hemolysin III
EYQ96_RS05265	COG2814	Major facilitator Superfamily
EYQ96_RS05270	COG0489	protein tyrosine kinase activity
EYQ96_RS05325	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
EYQ96_RS05350	COG3711	transcriptional antiterminator
EYQ96_RS05365	COG0561	phosphatase activity
EYQ96_RS05385	COG0640	Transcriptional regulator
EYQ96_RS05390	COG0702	epimerase
EYQ96_RS05395	COG1482	cell wall glycoprotein biosynthetic process
EYQ96_RS05415	COG0783	Belongs to the Dps family
EYQ96_RS05425	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
EYQ96_RS05430	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
EYQ96_RS05435	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
EYQ96_RS05445	COG1854	S-ribosylhomocysteine lyase activity
EYQ96_RS05480	COG0504	CTP synthase activity
EYQ96_RS05490	COG0191	fructose-bisphosphate aldolase activity
EYQ96_RS05505	COG1012	belongs to the aldehyde dehydrogenase family
EYQ96_RS05510	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
EYQ96_RS05515	COG0254	rRNA binding
EYQ96_RS05520	COG1435	thymidine kinase activity
EYQ96_RS05530	COG2890	protein-(glutamine-N5) methyltransferase activity
EYQ96_RS05535	COG0009	L-threonylcarbamoyladenylate synthase
EYQ96_RS05540	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EYQ96_RS05545	COG4475	Protein of unknown function (DUF436)
EYQ96_RS05555	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
EYQ96_RS05560	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
EYQ96_RS05585	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EYQ96_RS05600	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
EYQ96_RS05605	COG0355	proton-transporting ATP synthase activity, rotational mechanism
EYQ96_RS05620	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EYQ96_RS05630	COG0629	single-stranded DNA binding
EYQ96_RS05640	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
EYQ96_RS05650	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
EYQ96_RS05655	COG0352	thiamine-phosphate diphosphorylase activity
EYQ96_RS05660	COG0706	membrane insertase activity
EYQ96_RS05665	COG1418	mRNA catabolic process
EYQ96_RS05670	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EYQ96_RS05675	COG1937	Protein conserved in bacteria
EYQ96_RS05690	COG0772	Belongs to the SEDS family
EYQ96_RS05695	COG1181	Belongs to the D-alanine--D-alanine ligase family
EYQ96_RS05700	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
EYQ96_RS05705	COG0513	Belongs to the DEAD box helicase family
EYQ96_RS05715	COG3428	Bacterial PH domain
EYQ96_RS05725	COG0736	holo-[acyl-carrier-protein] synthase activity
EYQ96_RS05730	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EYQ96_RS05740	COG2337	Toxic component of a toxin-antitoxin (TA) module
EYQ96_RS05745	COG2208	phosphoserine phosphatase activity
EYQ96_RS05760	COG1191	sigma factor activity
EYQ96_RS05765	COG2183	response to ionizing radiation
EYQ96_RS05810	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
EYQ96_RS05815	COG0473	3-isopropylmalate dehydrogenase activity
EYQ96_RS05835	COG0028	Belongs to the TPP enzyme family
EYQ96_RS05840	COG0129	dihydroxy-acid dehydratase activity
EYQ96_RS05845	COG0802	atpase or kinase
EYQ96_RS05850	COG1214	PFAM Peptidase M22, glycoprotease
EYQ96_RS05855	COG0456	acetyltransferase
EYQ96_RS05860	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
EYQ96_RS05865	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
EYQ96_RS05870	COG0488	(ABC) transporter
EYQ96_RS05885	COG2391	methyltransferase activity
EYQ96_RS05890	COG0425	Belongs to the sulfur carrier protein TusA family
EYQ96_RS05895	COG1609	Transcriptional regulator
EYQ96_RS05900	COG1621	beta-fructofuranosidase activity
EYQ96_RS05905	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EYQ96_RS05965	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
EYQ96_RS05970	COG0459	protein refolding
EYQ96_RS05995	COG1725	Transcriptional regulator
EYQ96_RS06010	COG1131	(ABC) transporter
EYQ96_RS06080	COG0456	acetyltransferase
EYQ96_RS06120	COG0640	Transcriptional regulator
EYQ96_RS06130	COG2226	methyltransferase
EYQ96_RS06140	COG2706	6-phosphogluconolactonase activity
EYQ96_RS06145	COG1012	belongs to the aldehyde dehydrogenase family
EYQ96_RS06150	COG1227	inorganic diphosphatase activity
EYQ96_RS06155	COG1335	isochorismatase
EYQ96_RS06165	COG0077	Prephenate dehydratase
EYQ96_RS06175	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
EYQ96_RS06180	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
EYQ96_RS06185	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
EYQ96_RS06195	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
EYQ96_RS06200	COG4496	protein, YerC YecD
EYQ96_RS06205	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
EYQ96_RS06210	COG0210	DNA helicase
EYQ96_RS06215	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
EYQ96_RS06225	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EYQ96_RS06240	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EYQ96_RS06245	COG1597	lipid kinase activity
EYQ96_RS06250	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EYQ96_RS06280	COG1528	Iron-storage protein
EYQ96_RS06295	COG4129	membrane
EYQ96_RS06300	COG0024	Methionine aminopeptidase
EYQ96_RS06320	COG2197	response regulator
EYQ96_RS06325	COG1295	ribonuclease BN
EYQ96_RS06340	COG4840	Belongs to the UPF0435 family
EYQ96_RS06345	COG2309	aminopeptidase activity
EYQ96_RS06355	COG0535	radical SAM domain protein
EYQ96_RS06365	COG0693	protein deglycase activity
EYQ96_RS06370	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EYQ96_RS06385	COG1134	teichoic acid transport
EYQ96_RS06385	COG1388	LysM domain
EYQ96_RS06395	COG1988	membrane-bound metal-dependent
EYQ96_RS06400	COG1194	a g-specific adenine glycosylase
EYQ96_RS06405	COG3557	Belongs to the UPF0374 family
EYQ96_RS06415	COG4129	membrane
EYQ96_RS06420	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
EYQ96_RS06425	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EYQ96_RS06430	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EYQ96_RS06435	COG0735	belongs to the Fur family
EYQ96_RS06600	COG0765	amino acid transport
EYQ96_RS06605	COG1126	abc transporter atp-binding protein
EYQ96_RS06610	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
EYQ96_RS06620	COG0363	glucosamine-6-phosphate deaminase activity
EYQ96_RS06635	COG0114	fumarate hydratase activity
EYQ96_RS06640	COG0564	pseudouridine synthase activity
EYQ96_RS06645	COG4585	Histidine kinase
EYQ96_RS06645	COG2203	Gaf domain
EYQ96_RS06650	COG2197	response regulator
EYQ96_RS06660	COG4399	Belongs to the UPF0754 family
EYQ96_RS06665	COG3679	Belongs to the UPF0342 family
EYQ96_RS06670	COG0420	3'-5' exonuclease activity
EYQ96_RS06680	COG3481	metal-dependent phosphohydrolase, HD sub domain
EYQ96_RS06690	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EYQ96_RS06705	COG0537	adenosine 5'-monophosphoramidase activity
EYQ96_RS06710	COG1131	(ABC) transporter
EYQ96_RS06715	COG4473	ABC transporter
EYQ96_RS06720	COG2329	Antibiotic biosynthesis monooxygenase
EYQ96_RS06740	COG3545	Serine hydrolase
EYQ96_RS06790	COG0318	PFAM AMP-dependent synthetase and ligase
EYQ96_RS06810	COG1506	peptidase
EYQ96_RS06820	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
EYQ96_RS06830	COG0656	L-ascorbic acid biosynthetic process
EYQ96_RS06835	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EYQ96_RS06850	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
EYQ96_RS06875	COG4193	domain, Protein
EYQ96_RS06875	COG3266	domain, Protein
EYQ96_RS06875	COG5632	N-Acetylmuramoyl-L-alanine amidase
EYQ96_RS06885	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EYQ96_RS06885	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EYQ96_RS06890	COG0307	riboflavin synthase, alpha
EYQ96_RS06895	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EYQ96_RS06895	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EYQ96_RS06900	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
EYQ96_RS06905	COG0506	proline dehydrogenase activity
EYQ96_RS06910	COG2267	carboxylic ester hydrolase activity
EYQ96_RS06920	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
EYQ96_RS06925	COG1242	4 iron, 4 sulfur cluster binding
EYQ96_RS06930	COG2814	Major facilitator Superfamily
EYQ96_RS06935	COG0495	leucyl-tRNA aminoacylation
EYQ96_RS06940	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EYQ96_RS06955	COG2081	HI0933 family
EYQ96_RS06960	COG2244	polysaccharide biosynthetic process
EYQ96_RS06965	COG1187	pseudouridine synthase activity
EYQ96_RS06975	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EYQ96_RS06980	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EYQ96_RS06985	COG0510	thiamine kinase activity
EYQ96_RS06990	COG0220	tRNA (guanine-N7-)-methyltransferase activity
EYQ96_RS06995	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EYQ96_RS07005	COG1363	Peptidase, m42
EYQ96_RS07010	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EYQ96_RS07015	COG4848	Belongs to the UPF0354 family
EYQ96_RS07020	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EYQ96_RS07025	COG1674	ftsk spoiiie
EYQ96_RS07030	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
EYQ96_RS07045	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
EYQ96_RS07045	COG1605	Chorismate mutase
EYQ96_RS07050	COG1609	Transcriptional regulator
EYQ96_RS07060	COG0454	-acetyltransferase
EYQ96_RS07065	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EYQ96_RS07075	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
EYQ96_RS07090	COG2814	Major facilitator Superfamily
EYQ96_RS07095	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EYQ96_RS07100	COG0204	Acyl-transferase
EYQ96_RS07120	COG1263	PTS System
EYQ96_RS07120	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EYQ96_RS07130	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EYQ96_RS07140	COG1764	response to oxidative stress
EYQ96_RS07145	COG0584	glycerophosphoryl diester phosphodiesterase
EYQ96_RS07150	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
EYQ96_RS07155	COG1956	GAF domain-containing protein
EYQ96_RS07160	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
EYQ96_RS07165	COG1104	cysteine desulfurase activity
EYQ96_RS07170	COG0301	tRNA thio-modification
EYQ96_RS07180	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
EYQ96_RS07185	COG0827	DNA restriction-modification system
EYQ96_RS07190	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
EYQ96_RS07195	COG0589	response to stress
EYQ96_RS07200	COG0686	Belongs to the AlaDH PNT family
EYQ96_RS07205	COG0006	proline dipeptidase activity
EYQ96_RS07210	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
EYQ96_RS07220	COG4109	DRTGG domain
EYQ96_RS07225	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
EYQ96_RS07235	COG0281	malic enzyme
EYQ96_RS07240	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
EYQ96_RS07250	COG0205	6-phosphofructokinase activity
EYQ96_RS07255	COG0469	pyruvate kinase activity
EYQ96_RS07260	COG1113	amino acid transport
EYQ96_RS07265	COG0372	Belongs to the citrate synthase family
EYQ96_RS07270	COG0538	isocitrate dehydrogenase activity
EYQ96_RS07275	COG0745	RESPONSE REGULATOR receiver
EYQ96_RS07280	COG5002	protein histidine kinase activity
EYQ96_RS07285	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EYQ96_RS07285	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EYQ96_RS07290	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
EYQ96_RS07295	COG0237	dephospho-CoA kinase activity
EYQ96_RS07300	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EYQ96_RS07305	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
EYQ96_RS07310	COG3611	Membrane attachment protein
EYQ96_RS07315	COG1484	DNA-dependent DNA replication
EYQ96_RS07325	COG0833	amino acid
EYQ96_RS07330	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
EYQ96_RS07335	COG0291	Belongs to the bacterial ribosomal protein bL35 family
EYQ96_RS07340	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
EYQ96_RS07345	COG4112	unkown
EYQ96_RS07355	COG0544	peptidyl-prolyl cis-trans isomerase activity
EYQ96_RS07360	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
EYQ96_RS07365	COG0218	Necessary for normal cell division and for the maintenance of normal septation
EYQ96_RS07375	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EYQ96_RS07380	COG0181	hydroxymethylbilane synthase activity
EYQ96_RS07390	COG0113	porphobilinogen synthase activity
EYQ96_RS07395	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
EYQ96_RS07405	COG2818	Glycosylase
EYQ96_RS07410	COG0525	valine-tRNA ligase activity
EYQ96_RS07415	COG0285	dihydrofolate synthase activity
EYQ96_RS07425	COG2003	Belongs to the UPF0758 family
EYQ96_RS07460	COG0261	This protein binds to 23S rRNA in the presence of protein L20
EYQ96_RS07465	COG2868	ribosomal protein
EYQ96_RS07470	COG0211	Belongs to the bacterial ribosomal protein bL27 family
EYQ96_RS07475	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
EYQ96_RS07480	COG4492	Belongs to the UPF0735 family
EYQ96_RS07485	COG0632	four-way junction helicase activity
EYQ96_RS07495	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
EYQ96_RS07505	COG1862	Preprotein translocase
EYQ96_RS07510	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EYQ96_RS07510	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EYQ96_RS07515	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
EYQ96_RS07515	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
EYQ96_RS07525	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EYQ96_RS07535	COG0860	N-Acetylmuramoyl-L-alanine amidase
EYQ96_RS07545	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
EYQ96_RS07555	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
EYQ96_RS07560	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
EYQ96_RS07565	COG1959	2 iron, 2 sulfur cluster binding
EYQ96_RS07575	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EYQ96_RS07580	COG1104	cysteine desulfurase activity
EYQ96_RS07585	COG0482	sulfurtransferase activity
EYQ96_RS07595	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
EYQ96_RS07605	COG4472	Bacterial protein of unknown function (DUF965)
EYQ96_RS07610	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
EYQ96_RS07615	COG3906	Belongs to the UPF0473 family
EYQ96_RS07620	COG4122	O-methyltransferase activity
EYQ96_RS07635	COG0572	uridine kinase
EYQ96_RS07640	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EYQ96_RS07645	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
EYQ96_RS07650	COG1984	allophanate hydrolase subunit 2
EYQ96_RS07655	COG0511	ligase activity, forming carbon-carbon bonds
EYQ96_RS07660	COG0439	Biotin carboxylase
EYQ96_RS07665	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
EYQ96_RS07670	COG1914	H( )-stimulated, divalent metal cation uptake system
EYQ96_RS07675	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EYQ96_RS07680	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
EYQ96_RS07685	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
EYQ96_RS07690	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
EYQ96_RS07695	COG1534	Rna-binding protein
EYQ96_RS07700	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
EYQ96_RS07705	COG1713	HD superfamily hydrolase involved in NAD metabolism
EYQ96_RS07710	COG0799	negative regulation of ribosome biogenesis
EYQ96_RS07715	COG4106	trans-aconitate 2-methyltransferase activity
EYQ96_RS07720	COG1555	photosystem II stabilization
EYQ96_RS07720	COG1596	polysaccharide export
EYQ96_RS07725	COG2131	deaminase
EYQ96_RS07730	COG2333	competence protein COMEC
EYQ96_RS07730	COG0658	competence protein
EYQ96_RS07735	COG1466	dna polymerase III delta subunit
EYQ96_RS07740	COG0268	Binds directly to 16S ribosomal RNA
EYQ96_RS07745	COG0481	GTPase activity
EYQ96_RS07750	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EYQ96_RS07760	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
EYQ96_RS07765	COG0443	Heat shock 70 kDa protein
EYQ96_RS07770	COG0484	heat shock protein binding
EYQ96_RS07780	COG1385	rRNA (uridine-N3-)-methyltransferase activity
EYQ96_RS07785	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EYQ96_RS07795	COG1030	water channel activity
EYQ96_RS07800	COG4864	UPF0365 protein
EYQ96_RS07810	COG1702	phosphate starvation-inducible protein PhoH
EYQ96_RS07830	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
EYQ96_RS07835	COG1381	Involved in DNA repair and RecF pathway recombination
EYQ96_RS07840	COG0423	glycine-tRNA ligase activity
EYQ96_RS07845	COG0517	IMP dehydrogenase activity
EYQ96_RS07850	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
EYQ96_RS07855	COG0358	DNA primase activity
EYQ96_RS07860	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EYQ96_RS07865	COG2384	SAM-dependent methyltransferase
EYQ96_RS07870	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
EYQ96_RS07875	COG0513	Belongs to the DEAD box helicase family
EYQ96_RS07880	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
EYQ96_RS07885	COG1121	(ABC) transporter
EYQ96_RS07890	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EYQ96_RS07910	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EYQ96_RS07915	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
EYQ96_RS07925	COG4483	Protein conserved in bacteria
EYQ96_RS07930	COG1940	carbohydrate kinase activity
EYQ96_RS07935	COG0011	TIGRFAM Protein of
EYQ96_RS07940	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EYQ96_RS07945	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EYQ96_RS07950	COG1459	type II secretion system
EYQ96_RS07955	COG4537	Required for transformation and DNA binding
EYQ96_RS07970	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
EYQ96_RS07975	COG0404	The glycine cleavage system catalyzes the degradation of glycine
EYQ96_RS07990	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EYQ96_RS07995	COG0095	Lipoate-protein ligase
EYQ96_RS08010	COG0006	proline dipeptidase activity
EYQ96_RS08015	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
EYQ96_RS08020	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
EYQ96_RS08025	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
EYQ96_RS08030	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
EYQ96_RS08035	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EYQ96_RS08040	COG0511	ligase activity, forming carbon-carbon bonds
EYQ96_RS08045	COG0439	Biotin carboxylase
EYQ96_RS08050	COG1302	Protein conserved in bacteria
EYQ96_RS08055	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EYQ96_RS08065	COG1722	exodeoxyribonuclease VII activity
EYQ96_RS08075	COG1438	arginine binding
EYQ96_RS08080	COG0497	DNA recombination
EYQ96_RS08085	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EYQ96_RS08090	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EYQ96_RS08095	COG0022	dehydrogenase e1 component
EYQ96_RS08100	COG0508	dehydrogenase complex catalyzes the overall conversion of
EYQ96_RS08110	COG4129	membrane
EYQ96_RS08115	COG2195	Cleaves the N-terminal amino acid of tripeptides
EYQ96_RS08120	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
EYQ96_RS08125	COG0366	Alpha amylase catalytic
EYQ96_RS08135	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
EYQ96_RS08140	COG1234	tRNA 3'-trailer cleavage
EYQ96_RS08150	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EYQ96_RS08155	COG1028	Short-chain dehydrogenase reductase Sdr
EYQ96_RS08160	COG0667	Aldo Keto reductase
EYQ96_RS08165	COG0494	nUDIX hydrolase
EYQ96_RS08170	COG0735	belongs to the Fur family
EYQ96_RS08175	COG4974	Belongs to the 'phage' integrase family
EYQ96_RS08185	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
EYQ96_RS08190	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
EYQ96_RS08195	COG1187	pseudouridine synthase activity
EYQ96_RS08200	COG0745	RESPONSE REGULATOR receiver
EYQ96_RS08215	COG1141	Ferredoxin
EYQ96_RS08225	COG0514	ATP-dependent DNA helicase (RecQ)
EYQ96_RS08235	COG0492	ferredoxin-NADP+ reductase activity
EYQ96_RS08250	COG0539	negative regulation of cytoplasmic translation
EYQ96_RS08255	COG1160	GTP binding
EYQ96_RS08260	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
EYQ96_RS08275	COG2226	methyltransferase
EYQ96_RS08290	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
EYQ96_RS08295	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
EYQ96_RS08300	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
EYQ96_RS08310	COG5582	Belongs to the UPF0302 family
EYQ96_RS08315	COG4347	Protein of unknown function (DUF1405)
EYQ96_RS08320	COG2738	Putative neutral zinc metallopeptidase
EYQ96_RS08325	COG1694	Mazg nucleotide pyrophosphohydrolase
EYQ96_RS08330	COG0438	transferase activity, transferring glycosyl groups
EYQ96_RS08335	COG0617	tRNA 3'-terminal CCA addition
EYQ96_RS08340	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
EYQ96_RS08340	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
EYQ96_RS08345	COG1199	ATP-dependent helicase activity
EYQ96_RS08345	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EYQ96_RS08350	COG0017	Asparaginyl-tRNA synthetase
EYQ96_RS08355	COG3935	DnaD domain protein
EYQ96_RS08360	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
EYQ96_RS08370	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EYQ96_RS08370	COG4499	WXG100 protein secretion system (Wss), protein YukC
EYQ96_RS08375	COG3331	DNA recombination
EYQ96_RS08390	COG3599	regulation of cell shape
EYQ96_RS08400	COG0116	Belongs to the methyltransferase superfamily
EYQ96_RS08410	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
EYQ96_RS08415	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EYQ96_RS08430	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
EYQ96_RS08440	COG1413	lyase activity
EYQ96_RS08445	COG1413	lyase activity
EYQ96_RS08475	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EYQ96_RS08480	COG2190	(PTS) system
EYQ96_RS08490	COG0793	Belongs to the peptidase S41A family
EYQ96_RS08500	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
EYQ96_RS08505	COG0671	phosphoesterase, PA-phosphatase related
EYQ96_RS08510	COG0745	RESPONSE REGULATOR receiver
EYQ96_RS08515	COG5002	protein histidine kinase activity
EYQ96_RS08520	COG0567	Dehydrogenase, E1 component
EYQ96_RS08525	COG0508	dehydrogenase complex catalyzes the overall conversion of
EYQ96_RS08530	COG1131	(ABC) transporter
EYQ96_RS08550	COG0714	Associated with various cellular activities
EYQ96_RS08555	COG4548	von Willebrand factor, type A
EYQ96_RS08560	COG1114	Component of the transport system for branched-chain amino acids
EYQ96_RS08565	COG3853	Toxic anion resistance protein (TelA)
EYQ96_RS08575	COG1254	Belongs to the acylphosphatase family
EYQ96_RS08585	COG1278	Cold shock
EYQ96_RS08600	COG1473	amidohydrolase
EYQ96_RS08610	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
EYQ96_RS08615	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EYQ96_RS08620	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EYQ96_RS08625	COG0527	aspartate kinase activity
EYQ96_RS08630	COG0488	(ABC) transporter
EYQ96_RS08635	COG2996	Protein conserved in bacteria
EYQ96_RS08640	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
EYQ96_RS08645	COG0573	inorganic phosphate transmembrane transporter activity
EYQ96_RS08650	COG0581	inorganic phosphate transmembrane transporter activity
EYQ96_RS08655	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
EYQ96_RS08695	COG4607	ABC-type enterochelin transport system periplasmic component
EYQ96_RS08700	COG0561	phosphatase activity
EYQ96_RS08705	COG2348	transferase activity, transferring amino-acyl groups
EYQ96_RS08710	COG2348	transferase activity, transferring amino-acyl groups
EYQ96_RS08730	COG0134	indole-3-glycerol-phosphate synthase activity
EYQ96_RS08740	COG0512	Glutamine amidotransferase of anthranilate synthase
EYQ96_RS08745	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EYQ96_RS08750	COG1363	Peptidase, m42
EYQ96_RS08755	COG0287	Prephenate dehydrogenase
EYQ96_RS08760	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EYQ96_RS08765	COG1942	4-Oxalocrotonate Tautomerase
EYQ96_RS08780	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
EYQ96_RS08780	COG0392	lysyltransferase activity
EYQ96_RS08785	COG0628	permease
EYQ96_RS08790	COG3711	transcriptional antiterminator
EYQ96_RS08795	COG1115	amino acid carrier protein
EYQ96_RS08800	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EYQ96_RS08805	COG0187	DNA topoisomerase II activity
EYQ96_RS08820	COG0824	Thioesterase
EYQ96_RS08825	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
EYQ96_RS08830	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EYQ96_RS08835	COG1970	mechanosensitive ion channel activity
EYQ96_RS08850	COG4846	Membrane protein involved in cytochrome C biogenesis
EYQ96_RS08860	COG3763	UPF0154 protein
EYQ96_RS08875	COG4224	UPF0291 protein
EYQ96_RS08900	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
EYQ96_RS08915	COG0833	amino acid
EYQ96_RS08930	COG0083	homoserine kinase activity
EYQ96_RS08935	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
EYQ96_RS08940	COG0460	homoserine dehydrogenase
EYQ96_RS08945	COG0527	aspartate kinase activity
EYQ96_RS08960	COG1525	nuclease
EYQ96_RS08975	COG2197	response regulator
EYQ96_RS08980	COG4585	Histidine kinase
EYQ96_RS09035	COG0789	Transcriptional regulator
EYQ96_RS09040	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
EYQ96_RS09050	COG0386	Belongs to the glutathione peroxidase family
EYQ96_RS09055	COG1923	regulation of RNA biosynthetic process
EYQ96_RS09060	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
EYQ96_RS09070	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
EYQ96_RS09080	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
EYQ96_RS09085	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
EYQ96_RS09090	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
EYQ96_RS09110	COG4550	Control of competence regulator ComK, YlbF/YmcA
EYQ96_RS09115	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EYQ96_RS09125	COG4195	phage-related replication protein
EYQ96_RS09130	COG1013	pyruvate-flavodoxin oxidoreductase activity
EYQ96_RS09135	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
EYQ96_RS09135	COG0674	pyruvate-flavodoxin oxidoreductase activity
EYQ96_RS09140	COG1692	metallophosphoesterase
EYQ96_RS09150	COG1418	mRNA catabolic process
EYQ96_RS09155	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
EYQ96_RS09160	COG1058	Belongs to the CinA family
EYQ96_RS09160	COG1546	Belongs to the CinA family
EYQ96_RS09180	COG1028	Short-chain dehydrogenase reductase Sdr
EYQ96_RS09185	COG0612	Peptidase, M16
EYQ96_RS09190	COG0612	Peptidase, M16
EYQ96_RS09195	COG2188	Transcriptional regulator
EYQ96_RS09205	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EYQ96_RS09210	COG1185	polyribonucleotide nucleotidyltransferase activity
EYQ96_RS09215	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
EYQ96_RS09220	COG0196	riboflavin kinase activity
EYQ96_RS09225	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
EYQ96_RS09230	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
EYQ96_RS09235	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
EYQ96_RS09240	COG1358	cellular component organization or biogenesis
EYQ96_RS09245	COG2740	Nucleic-acid-binding protein implicated in transcription termination
EYQ96_RS09250	COG0195	Participates in both transcription termination and antitermination
EYQ96_RS09255	COG0779	Required for maturation of 30S ribosomal subunits
EYQ96_RS09260	COG2176	DNA-directed DNA polymerase activity
EYQ96_RS09265	COG0442	prolyl-tRNA aminoacylation
EYQ96_RS09275	COG4589	Belongs to the CDS family
EYQ96_RS09280	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
EYQ96_RS09285	COG0233	cytoplasmic translational termination
EYQ96_RS09290	COG0528	UMP kinase activity
EYQ96_RS09295	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
EYQ96_RS09300	COG0052	Belongs to the universal ribosomal protein uS2 family
EYQ96_RS09315	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
EYQ96_RS09320	COG4974	Belongs to the 'phage' integrase family
EYQ96_RS09325	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
EYQ96_RS09330	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EYQ96_RS09335	COG0758	DNA mediated transformation
EYQ96_RS09340	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
EYQ96_RS09345	COG0045	succinate-CoA ligase (ADP-forming) activity
EYQ96_RS09350	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EYQ96_RS09360	COG4485	Bacterial membrane protein, YfhO
EYQ96_RS09375	COG0336	Belongs to the RNA methyltransferase TrmD family
EYQ96_RS09380	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
EYQ96_RS09385	COG0228	four-way junction DNA binding
EYQ96_RS09390	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EYQ96_RS09395	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
EYQ96_RS09400	COG0552	protein localization to endoplasmic reticulum
EYQ96_RS09405	COG1196	nuclear chromosome segregation
EYQ96_RS09410	COG0571	ribonuclease III activity
EYQ96_RS09415	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EYQ96_RS09435	COG0416	fatty acid biosynthetic process
EYQ96_RS09440	COG1349	DNA-binding transcription factor activity
EYQ96_RS09445	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
EYQ96_RS09450	COG1461	Dihydroxyacetone kinase
EYQ96_RS09455	COG1302	Protein conserved in bacteria
EYQ96_RS09460	COG0227	Belongs to the bacterial ribosomal protein bL28 family
EYQ96_RS09470	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
EYQ96_RS09485	COG0631	protein serine/threonine phosphatase activity
EYQ96_RS09490	COG0820	rRNA (adenine-C2-)-methyltransferase activity
EYQ96_RS09495	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EYQ96_RS09495	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EYQ96_RS09500	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EYQ96_RS09515	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EYQ96_RS09520	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EYQ96_RS09525	COG1758	RNA polymerase activity
EYQ96_RS09530	COG0194	GDP metabolic process
EYQ96_RS09550	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
EYQ96_RS09555	COG0284	orotidine-5'-phosphate decarboxylase activity
EYQ96_RS09560	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
EYQ96_RS09565	COG0505	Belongs to the CarA family
EYQ96_RS09570	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
EYQ96_RS09575	COG0540	Belongs to the ATCase OTCase family
EYQ96_RS09580	COG2233	PERMEase
EYQ96_RS09585	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
EYQ96_RS09595	COG0564	pseudouridine synthase activity
EYQ96_RS09605	COG1388	LysM domain
EYQ96_RS09605	COG3942	CHAP domain
EYQ96_RS09615	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
EYQ96_RS09620	COG3599	regulation of cell shape
EYQ96_RS09630	COG0762	integral membrane protein
EYQ96_RS09635	COG1799	cell septum assembly
EYQ96_RS09640	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
EYQ96_RS09650	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
EYQ96_RS09655	COG0849	cell division
EYQ96_RS09660	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
EYQ96_RS09670	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EYQ96_RS09680	COG4839	cell division protein FtsL
EYQ96_RS09685	COG0275	rRNA processing
EYQ96_RS09695	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
EYQ96_RS09705	COG1011	Hydrolase
EYQ96_RS09750	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
EYQ96_RS09760	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
EYQ96_RS09765	COG1053	succinate dehydrogenase
EYQ96_RS09770	COG2009	succinate dehydrogenase
EYQ96_RS09775	COG0322	excinuclease ABC activity
EYQ96_RS09780	COG3118	belongs to the thioredoxin family
EYQ96_RS09785	COG1193	negative regulation of DNA recombination
EYQ96_RS09790	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
EYQ96_RS09790	COG1796	DNA polymerase
EYQ96_RS09800	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
EYQ96_RS09805	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EYQ96_RS09810	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EYQ96_RS09810	COG0072	phenylalanine-tRNA ligase activity
EYQ96_RS09815	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
EYQ96_RS09820	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EYQ96_RS09830	COG0333	Belongs to the bacterial ribosomal protein bL32 family
EYQ96_RS09845	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
EYQ96_RS09850	COG0742	ribosomal rna small subunit methyltransferase
EYQ96_RS09865	COG0584	glycerophosphoryl diester phosphodiesterase
EYQ96_RS09870	COG3679	Belongs to the UPF0342 family
EYQ96_RS09885	COG0109	protoheme IX farnesyltransferase activity
EYQ96_RS09890	COG1612	heme a metabolic process
EYQ96_RS09900	COG0772	Belongs to the SEDS family
EYQ96_RS09905	COG4838	Belongs to the UPF0358 family
EYQ96_RS09910	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
EYQ96_RS09915	COG4896	Protein conserved in bacteria
EYQ96_RS09930	COG0483	inositol monophosphate 1-phosphatase activity
EYQ96_RS09935	COG4493	Belongs to the UPF0637 family
EYQ96_RS09960	COG1177	transmembrane transport
EYQ96_RS09965	COG1176	ABC-type spermidine putrescine transport system, permease component I
EYQ96_RS09980	COG4476	Belongs to the UPF0223 family
EYQ96_RS09990	COG0508	dehydrogenase complex catalyzes the overall conversion of
EYQ96_RS10010	COG0242	peptide deformylase activity
EYQ96_RS10020	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EYQ96_RS10025	COG0569	domain protein
EYQ96_RS10030	COG1294	oxidase, subunit
EYQ96_RS10035	COG1271	oxidase subunit
EYQ96_RS10045	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EYQ96_RS10050	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EYQ96_RS10060	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
EYQ96_RS10080	COG4172	Belongs to the ABC transporter superfamily
EYQ96_RS10085	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EYQ96_RS10090	COG0151	Belongs to the GarS family
EYQ96_RS10095	COG0138	bifunctional purine biosynthesis protein purh
EYQ96_RS10105	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
EYQ96_RS10120	COG0047	phosphoribosylformylglycinamidine synthase activity
EYQ96_RS10125	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EYQ96_RS10130	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
EYQ96_RS10140	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
EYQ96_RS10145	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
EYQ96_RS10150	COG1017	nitric oxide dioxygenase activity
EYQ96_RS10150	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EYQ96_RS10160	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
EYQ96_RS10175	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
EYQ96_RS10190	COG1316	TRANSCRIPTIONal
EYQ96_RS10215	COG3594	Acyltransferase
EYQ96_RS10220	COG0436	Aminotransferase
EYQ96_RS10225	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
EYQ96_RS10235	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
EYQ96_RS10240	COG1169	isochorismate synthase
EYQ96_RS10245	COG1575	Belongs to the MenA family. Type 1 subfamily
EYQ96_RS10255	COG2314	TM2 domain
EYQ96_RS10290	COG4873	Protein conserved in bacteria
EYQ96_RS10305	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EYQ96_RS10315	COG0861	Integral membrane protein TerC family
EYQ96_RS10320	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
EYQ96_RS10330	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EYQ96_RS10335	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
EYQ96_RS10340	COG2814	Major facilitator Superfamily
EYQ96_RS10345	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
EYQ96_RS10350	COG2382	esterase
EYQ96_RS10355	COG1115	amino acid carrier protein
EYQ96_RS10360	COG0628	permease
EYQ96_RS10370	COG0475	glutathione-regulated potassium exporter activity
EYQ96_RS10370	COG0569	domain protein
EYQ96_RS10375	COG2239	Acts as a magnesium transporter
EYQ96_RS10380	COG0564	pseudouridine synthase activity
EYQ96_RS10385	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
EYQ96_RS10390	COG2357	RelA SpoT domain protein
EYQ96_RS10405	COG2346	COG2346, Truncated hemoglobins
EYQ96_RS10415	COG1164	Oligoendopeptidase f
EYQ96_RS10425	COG4862	establishment of competence for transformation
EYQ96_RS10430	COG1393	Belongs to the ArsC family
EYQ96_RS10435	COG0180	Tryptophanyl-tRNA synthetase
EYQ96_RS10440	COG4166	transmembrane transport
EYQ96_RS10445	COG4608	Belongs to the ABC transporter superfamily
EYQ96_RS10450	COG0444	Belongs to the ABC transporter superfamily
EYQ96_RS10455	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EYQ96_RS10460	COG0601	transmembrane transport
EYQ96_RS10475	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EYQ96_RS10485	COG0542	response to heat
EYQ96_RS10500	COG0561	phosphatase activity
EYQ96_RS10525	COG1074	ATP-dependent DNA helicase activity
EYQ96_RS10545	COG0398	Pfam SNARE associated Golgi protein
EYQ96_RS10555	COG0137	argininosuccinate synthase activity
EYQ96_RS10560	COG0165	Argininosuccinate lyase
EYQ96_RS10565	COG0584	glycerophosphoryl diester phosphodiesterase
EYQ96_RS10570	COG0584	glycerophosphoryl diester phosphodiesterase
EYQ96_RS10590	COG1902	pentaerythritol trinitrate reductase activity
EYQ96_RS10595	COG1098	S1 RNA binding domain
EYQ96_RS10615	COG2111	Na H antiporter
EYQ96_RS10620	COG1006	Multisubunit Na H antiporter MnhC subunit
EYQ96_RS10625	COG0651	ATP synthesis coupled electron transport
EYQ96_RS10635	COG2212	antiporter activity
EYQ96_RS10645	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
EYQ96_RS10655	COG2050	protein possibly involved in aromatic compounds catabolism
EYQ96_RS10660	COG2056	Na+-H+ antiporter family
EYQ96_RS10665	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
EYQ96_RS10675	COG0316	Belongs to the HesB IscA family
EYQ96_RS10680	COG4844	belongs to the
EYQ96_RS10685	COG1252	NADH dehydrogenase
EYQ96_RS10690	COG4837	Protein of unknown function (DUF1462)
EYQ96_RS10695	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
EYQ96_RS10700	COG0583	DNA-binding transcription factor activity
EYQ96_RS10710	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
EYQ96_RS10720	COG1696	Membrane protein involved in D-alanine export
EYQ96_RS10725	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EYQ96_RS10745	COG2445	Protein of unknown function DUF86
EYQ96_RS10755	COG4470	Protein conserved in bacteria
EYQ96_RS10760	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
EYQ96_RS10765	COG0737	Belongs to the 5'-nucleotidase family
EYQ96_RS10770	COG0730	response to heat
EYQ96_RS10775	COG1801	Protein of unknown function DUF72
EYQ96_RS10780	COG2070	2-Nitropropane dioxygenase
EYQ96_RS10785	COG1253	flavin adenine dinucleotide binding
EYQ96_RS10790	COG0719	Fe-S assembly protein
EYQ96_RS10795	COG0822	iron-sulfur transferase activity
EYQ96_RS10800	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EYQ96_RS10805	COG0719	Fe-S assembly protein
EYQ96_RS10810	COG0396	ATPase activity
EYQ96_RS10820	COG3237	CsbD-like
EYQ96_RS10825	COG1464	Belongs to the NlpA lipoprotein family
EYQ96_RS10830	COG2011	ABC-type metal ion transport system permease component
EYQ96_RS10835	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
EYQ96_RS10845	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
EYQ96_RS10850	COG0509	glycine decarboxylation via glycine cleavage system
EYQ96_RS10855	COG1393	Belongs to the ArsC family
EYQ96_RS10860	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EYQ96_RS10870	COG0710	3-dehydroquinate dehydratase activity
EYQ96_RS10875	COG1764	response to oxidative stress
EYQ96_RS10885	COG0406	alpha-ribazole phosphatase activity
EYQ96_RS10915	COG4195	phage-related replication protein
EYQ96_RS10940	COG1278	Cold shock
EYQ96_RS10995	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EYQ96_RS11010	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EYQ96_RS11015	COG3728	DNA packaging
EYQ96_RS11015	COG5484	DNA packaging
EYQ96_RS11090	COG0582	viral genome integration into host DNA
EYQ96_RS11105	COG0557	exoribonuclease II activity
EYQ96_RS11110	COG1647	Serine aminopeptidase, S33
EYQ96_RS11115	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EYQ96_RS11125	COG0148	phosphopyruvate hydratase activity
EYQ96_RS11130	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
EYQ96_RS11135	COG0149	triose-phosphate isomerase activity
EYQ96_RS11140	COG0126	phosphoglycerate kinase activity
EYQ96_RS11150	COG2390	Transcriptional regulator
EYQ96_RS11175	COG0740	serine-type endopeptidase activity
EYQ96_RS11185	COG1481	regulation of sporulation
EYQ96_RS11190	COG0391	Required for morphogenesis under gluconeogenic growth conditions
EYQ96_RS11195	COG1660	Displays ATPase and GTPase activities
EYQ96_RS11200	COG0492	ferredoxin-NADP+ reductase activity
EYQ96_RS11215	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
EYQ96_RS11225	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EYQ96_RS11230	COG0556	nucleotide-excision repair
EYQ96_RS11245	COG1388	LysM domain
EYQ96_RS11245	COG3942	CHAP domain
EYQ96_RS11255	COG0653	protein targeting
EYQ96_RS11260	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
EYQ96_RS11265	COG1040	competence protein
EYQ96_RS11280	COG1739	Uncharacterized protein family UPF0029
EYQ96_RS11285	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EYQ96_RS11305	COG2195	Cleaves the N-terminal amino acid of tripeptides
EYQ96_RS11310	COG1929	Belongs to the glycerate kinase type-1 family
EYQ96_RS11330	COG0812	UDP-N-acetylmuramate dehydrogenase activity
EYQ96_RS11345	COG4604	ABC transporter, ATP-binding protein
EYQ96_RS11350	COG4605	iron ion homeostasis
EYQ96_RS11355	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EYQ96_RS11360	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EYQ96_RS11365	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EYQ96_RS11370	COG1780	Probably involved in ribonucleotide reductase function
EYQ96_RS11385	COG3104	oligopeptide transport
EYQ96_RS11390	COG1597	lipid kinase activity
EYQ96_RS11400	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
EYQ96_RS11405	COG1174	glycine betaine transport
EYQ96_RS11415	COG0514	ATP-dependent DNA helicase (RecQ)
EYQ96_RS11420	COG0488	(ABC) transporter
EYQ96_RS11430	COG1368	sulfuric ester hydrolase activity
EYQ96_RS11460	COG0512	Glutamine amidotransferase of anthranilate synthase
EYQ96_RS11460	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EYQ96_RS11465	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
EYQ96_RS11470	COG0720	synthase
EYQ96_RS11485	COG0463	Glycosyl transferase, family 2
EYQ96_RS11490	COG0656	L-ascorbic acid biosynthetic process
EYQ96_RS11495	COG1253	flavin adenine dinucleotide binding
EYQ96_RS11500	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
EYQ96_RS11505	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EYQ96_RS11505	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EYQ96_RS11505	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EYQ96_RS11510	COG1105	Belongs to the carbohydrate kinase PfkB family
EYQ96_RS11515	COG1349	DNA-binding transcription factor activity
EYQ96_RS11520	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
EYQ96_RS11550	COG0471	metal ion transport
EYQ96_RS11555	COG0039	L-malate dehydrogenase activity
EYQ96_RS11565	COG4989	oxidoreductase activity
EYQ96_RS11570	COG0523	cobalamin synthesis protein
EYQ96_RS11580	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
EYQ96_RS11585	COG4988	ABC transporter
EYQ96_RS11590	COG1968	undecaprenyl-diphosphatase activity
EYQ96_RS11600	COG1671	Belongs to the UPF0178 family
EYQ96_RS11605	COG1611	Belongs to the LOG family
EYQ96_RS11610	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EYQ96_RS11615	COG1959	2 iron, 2 sulfur cluster binding
EYQ96_RS11625	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EYQ96_RS11650	COG2839	Protein conserved in bacteria
EYQ96_RS11655	COG2814	Major facilitator Superfamily
EYQ96_RS11660	COG0583	DNA-binding transcription factor activity
EYQ96_RS11675	COG0217	transcriptional regulatory protein
EYQ96_RS11685	COG2169	Transcriptional regulator
EYQ96_RS11700	COG3942	CHAP domain
EYQ96_RS11700	COG1388	LysM domain
EYQ96_RS11710	COG0306	phosphate transporter
EYQ96_RS11715	COG1392	Phosphate transport regulator
EYQ96_RS11725	COG0577	efflux transmembrane transporter activity
EYQ96_RS11730	COG1136	(ABC) transporter
EYQ96_RS11735	COG2205	protein histidine kinase activity
EYQ96_RS11745	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EYQ96_RS11760	COG3949	Membrane
EYQ96_RS11770	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
EYQ96_RS11780	COG2376	Dihydroxyacetone kinase
EYQ96_RS11785	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EYQ96_RS11790	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EYQ96_RS11795	COG1120	ATPase activity
EYQ96_RS11800	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EYQ96_RS11805	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EYQ96_RS11810	COG1132	(ABC) transporter
EYQ96_RS11815	COG1686	Belongs to the peptidase S11 family
EYQ96_RS11820	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
EYQ96_RS11830	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
EYQ96_RS11835	COG1682	transport, permease protein
EYQ96_RS11840	COG1134	teichoic acid transport
EYQ96_RS11845	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
EYQ96_RS11860	COG1121	(ABC) transporter
EYQ96_RS11865	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EYQ96_RS11870	COG0803	Belongs to the bacterial solute-binding protein 9 family
EYQ96_RS11880	COG1320	monovalent cation:proton antiporter activity
EYQ96_RS11890	COG1863	multisubunit Na H antiporter MnhE subunit
EYQ96_RS11895	COG0651	ATP synthesis coupled electron transport
EYQ96_RS11900	COG1006	Multisubunit Na H antiporter MnhC subunit
EYQ96_RS11905	COG2111	Na H antiporter
EYQ96_RS11910	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EYQ96_RS11910	COG2111	Na H antiporter
EYQ96_RS11945	COG2267	carboxylic ester hydrolase activity
EYQ96_RS11965	COG0546	phosphoglycolate phosphatase activity
EYQ96_RS11970	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EYQ96_RS11975	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EYQ96_RS11980	COG0534	Mate efflux family protein
EYQ96_RS11995	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
EYQ96_RS12000	COG0018	arginyl-trna synthetase
EYQ96_RS12020	COG3875	lactate racemase activity
EYQ96_RS12025	COG1606	tRNA processing
EYQ96_RS12030	COG1691	(AIR) carboxylase
EYQ96_RS12035	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
EYQ96_RS12045	COG1078	dGTPase activity
EYQ96_RS12050	COG0519	Catalyzes the synthesis of GMP from XMP
EYQ96_RS12055	COG0655	NAD(P)H dehydrogenase (quinone) activity
EYQ96_RS12060	COG0667	Aldo Keto reductase
EYQ96_RS12065	COG4844	belongs to the
EYQ96_RS12080	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
EYQ96_RS12085	COG0095	Lipoate-protein ligase
EYQ96_RS12090	COG0280	phosphate acetyltransferase
EYQ96_RS12115	COG2363	Small membrane protein
EYQ96_RS12155	COG0477	Major facilitator Superfamily
EYQ96_RS12170	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
EYQ96_RS12175	COG0363	glucosamine-6-phosphate deaminase activity
EYQ96_RS12185	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EYQ96_RS12190	COG1469	GTP cyclohydrolase I activity
EYQ96_RS12195	COG2271	Major facilitator Superfamily
EYQ96_RS12200	COG0438	transferase activity, transferring glycosyl groups
EYQ96_RS12220	COG0561	phosphatase activity
EYQ96_RS12230	COG1428	Deoxynucleoside kinase
EYQ96_RS12235	COG1428	Deoxynucleoside kinase
EYQ96_RS12240	COG0546	phosphoglycolate phosphatase activity
EYQ96_RS12245	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EYQ96_RS12255	COG0737	Belongs to the 5'-nucleotidase family
EYQ96_RS12270	COG1063	alcohol dehydrogenase
EYQ96_RS12275	COG2814	Major facilitator Superfamily
EYQ96_RS12280	COG1349	DNA-binding transcription factor activity
EYQ96_RS12305	COG1473	amidohydrolase
EYQ96_RS12310	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
EYQ96_RS12315	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
EYQ96_RS12320	COG0049	tRNA binding
EYQ96_RS12325	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
EYQ96_RS12335	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EYQ96_RS12340	COG0085	RNA polymerase activity
EYQ96_RS12345	COG2813	Specifically methylates the guanine in position
EYQ96_RS12350	COG0222	ribosome binding
EYQ96_RS12355	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
EYQ96_RS12360	COG0081	regulation of translation
EYQ96_RS12365	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
EYQ96_RS12370	COG0250	Participates in transcription elongation, termination and antitermination
EYQ96_RS12380	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EYQ96_RS12390	COG3688	RNA-binding protein containing a PIN domain
EYQ96_RS12400	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
EYQ96_RS12405	COG0215	cysteine-tRNA ligase activity
EYQ96_RS12415	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EYQ96_RS12420	COG4956	integral membrane protein (PIN domain superfamily)
EYQ96_RS12425	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
EYQ96_RS12430	COG0542	response to heat
EYQ96_RS12435	COG3869	Catalyzes the specific phosphorylation of arginine residues in
EYQ96_RS12440	COG3880	PFAM UvrB UvrC protein
EYQ96_RS12450	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EYQ96_RS12455	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
EYQ96_RS12460	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
EYQ96_RS12465	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs