locus-tag	class	description
DWB98_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
DWB98_RS00010	COG0592	DNA-directed DNA polymerase activity
DWB98_RS00015	COG2501	S4 domain
DWB98_RS00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
DWB98_RS00035	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
DWB98_RS00040	COG2986	histidine ammonia-lyase
DWB98_RS00045	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
DWB98_RS00050	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
DWB98_RS00060	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
DWB98_RS00070	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
DWB98_RS00075	COG0359	binds to the 23S rRNA
DWB98_RS00080	COG0305	Participates in initiation and elongation during chromosome replication
DWB98_RS00085	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
DWB98_RS00090	COG1819	glycosyl
DWB98_RS00105	COG0745	RESPONSE REGULATOR receiver
DWB98_RS00110	COG5002	protein histidine kinase activity
DWB98_RS00125	COG2211	Major facilitator Superfamily
DWB98_RS00135	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
DWB98_RS00140	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
DWB98_RS00175	COG0640	Transcriptional regulator
DWB98_RS00190	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
DWB98_RS00195	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DWB98_RS00200	COG0640	Transcriptional regulator
DWB98_RS00215	COG1388	LysM domain
DWB98_RS00245	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
DWB98_RS00260	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
DWB98_RS00300	COG1210	Utp--glucose-1-phosphate uridylyltransferase
DWB98_RS00305	COG1215	transferase activity, transferring glycosyl groups
DWB98_RS00305	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
DWB98_RS00310	COG1215	transferase activity, transferring glycosyl groups
DWB98_RS00310	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
DWB98_RS00320	COG1216	Glycosyl transferase, family 2
DWB98_RS00330	COG0583	DNA-binding transcription factor activity
DWB98_RS00340	COG3181	Tripartite tricarboxylate transporter family receptor
DWB98_RS00370	COG3314	Sporulation integral membrane protein YlbJ
DWB98_RS00375	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
DWB98_RS00380	COG1942	4-Oxalocrotonate Tautomerase
DWB98_RS00390	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
DWB98_RS00395	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
DWB98_RS00405	COG1136	(ABC) transporter
DWB98_RS00420	COG0702	epimerase
DWB98_RS00425	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
DWB98_RS00460	COG0415	Belongs to the DNA photolyase family
DWB98_RS00475	COG3711	transcriptional antiterminator
DWB98_RS00480	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DWB98_RS00480	COG1263	PTS System
DWB98_RS00485	COG2723	6-phospho-beta-galactosidase activity
DWB98_RS00500	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
DWB98_RS00505	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DWB98_RS00510	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DWB98_RS00515	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
DWB98_RS00540	COG0601	transmembrane transport
DWB98_RS00550	COG0444	Belongs to the ABC transporter superfamily
DWB98_RS00555	COG1124	(ABC) transporter
DWB98_RS00585	COG0583	DNA-binding transcription factor activity
DWB98_RS00590	COG2207	Transcriptional regulator
DWB98_RS00595	COG2211	Major facilitator Superfamily
DWB98_RS00600	COG3250	beta-galactosidase activity
DWB98_RS00605	COG2814	Major facilitator Superfamily
DWB98_RS00630	COG2814	Major facilitator Superfamily
DWB98_RS00635	COG0463	Glycosyl transferase, family 2
DWB98_RS00650	COG1695	Transcriptional regulator
DWB98_RS00655	COG1028	Short-chain dehydrogenase reductase Sdr
DWB98_RS00660	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DWB98_RS00675	COG3192	ethanolamine utilization protein
DWB98_RS00680	COG1028	Short-chain dehydrogenase reductase Sdr
DWB98_RS00690	COG1012	belongs to the aldehyde dehydrogenase family
DWB98_RS00695	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DWB98_RS00705	COG2318	DinB family
DWB98_RS00730	COG1388	LysM domain
DWB98_RS00735	COG1388	LysM domain
DWB98_RS00740	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
DWB98_RS00750	COG1054	Belongs to the UPF0176 family
DWB98_RS00760	COG1609	Transcriptional regulator
DWB98_RS00770	COG0235	Class ii aldolase
DWB98_RS00775	COG2160	L-arabinose isomerase activity
DWB98_RS00790	COG1131	(ABC) transporter
DWB98_RS00800	COG1695	Transcriptional regulator
DWB98_RS00805	COG3479	Phenolic acid decarboxylase
DWB98_RS00810	COG3964	amidohydrolase
DWB98_RS00825	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DWB98_RS00830	COG2188	Transcriptional regulator
DWB98_RS00845	COG1070	Carbohydrate kinase
DWB98_RS00850	COG2115	Belongs to the xylose isomerase family
DWB98_RS00855	COG1846	Transcriptional regulator
DWB98_RS00855	COG1940	carbohydrate kinase activity
DWB98_RS00860	COG1511	domain protein
DWB98_RS00875	COG2207	Transcriptional regulator
DWB98_RS00875	COG1917	Cupin 2, conserved barrel domain protein
DWB98_RS00885	COG1070	Carbohydrate kinase
DWB98_RS00890	COG0352	thiamine-phosphate diphosphorylase activity
DWB98_RS00895	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DWB98_RS00905	COG2022	thiamine diphosphate biosynthetic process
DWB98_RS00910	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
DWB98_RS00915	COG1328	CTP reductase activity
DWB98_RS00920	COG0602	queuosine metabolic process
DWB98_RS00925	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
DWB98_RS00935	COG0431	NADPH-dependent FMN reductase
DWB98_RS00945	COG0346	lactoylglutathione lyase activity
DWB98_RS00950	COG2188	Transcriptional regulator
DWB98_RS00955	COG2084	Dehydrogenase
DWB98_RS00985	COG1115	amino acid carrier protein
DWB98_RS01005	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
DWB98_RS01010	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
DWB98_RS01015	COG0579	oxidoreductase
DWB98_RS01060	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
DWB98_RS01075	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
DWB98_RS01080	COG2814	Major facilitator Superfamily
DWB98_RS01090	COG0584	glycerophosphoryl diester phosphodiesterase
DWB98_RS01100	COG0668	transmembrane transport
DWB98_RS01105	COG1846	Transcriptional regulator
DWB98_RS01110	COG3961	Belongs to the TPP enzyme family
DWB98_RS01130	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DWB98_RS01170	COG0673	inositol 2-dehydrogenase activity
DWB98_RS01175	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
DWB98_RS01180	COG1691	(AIR) carboxylase
DWB98_RS01185	COG1606	tRNA processing
DWB98_RS01190	COG3875	lactate racemase activity
DWB98_RS01200	COG1929	Belongs to the glycerate kinase type-1 family
DWB98_RS01205	COG3835	regulator
DWB98_RS01210	COG0574	Belongs to the PEP-utilizing enzyme family
DWB98_RS01210	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DWB98_RS01215	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
DWB98_RS01220	COG2764	glyoxalase bleomycin resistance protein dioxygenase
DWB98_RS01240	COG1476	TRANSCRIPTIONal
DWB98_RS01245	COG2807	transmembrane transport
DWB98_RS01255	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DWB98_RS01260	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
DWB98_RS01265	COG1012	belongs to the aldehyde dehydrogenase family
DWB98_RS01270	COG0531	amino acid
DWB98_RS01285	COG2226	methyltransferase
DWB98_RS01290	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
DWB98_RS01295	COG1510	regulation of RNA biosynthetic process
DWB98_RS01300	COG1012	belongs to the aldehyde dehydrogenase family
DWB98_RS01305	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
DWB98_RS01315	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
DWB98_RS01315	COG0463	Glycosyl transferase, family 2
DWB98_RS01325	COG0778	Nitroreductase
DWB98_RS01330	COG2843	Capsule synthesis protein
DWB98_RS01335	COG1957	nucleoside hydrolase
DWB98_RS01340	COG0477	Major facilitator Superfamily
DWB98_RS01360	COG1131	(ABC) transporter
DWB98_RS01365	COG0531	amino acid
DWB98_RS01370	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
DWB98_RS01375	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
DWB98_RS01380	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
DWB98_RS01385	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
DWB98_RS01390	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DWB98_RS01395	COG0431	NADPH-dependent FMN reductase
DWB98_RS01400	COG3226	Transcriptional regulator
DWB98_RS01420	COG2610	gluconate transmembrane transporter activity
DWB98_RS01425	COG1063	alcohol dehydrogenase
DWB98_RS01430	COG1620	l-lactate permease
DWB98_RS01435	COG2814	Major facilitator Superfamily
DWB98_RS01440	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
DWB98_RS01445	COG1263	PTS System
DWB98_RS01445	COG2190	(PTS) system
DWB98_RS01445	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DWB98_RS01450	COG0363	glucosamine-6-phosphate deaminase activity
DWB98_RS01460	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
DWB98_RS01465	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DWB98_RS01475	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DWB98_RS01485	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
DWB98_RS01500	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DWB98_RS01505	COG0765	amino acid transport
DWB98_RS01510	COG1126	abc transporter atp-binding protein
DWB98_RS01515	COG3711	transcriptional antiterminator
DWB98_RS01520	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DWB98_RS01530	COG3037	sugar-specific permease SgaT UlaA
DWB98_RS01535	COG4297	protein containing double-stranded beta helix domain
DWB98_RS01545	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
DWB98_RS01555	COG1464	Belongs to the NlpA lipoprotein family
DWB98_RS01560	COG0039	L-malate dehydrogenase activity
DWB98_RS01565	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DWB98_RS01565	COG3711	transcriptional antiterminator
DWB98_RS01570	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DWB98_RS01570	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DWB98_RS01570	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DWB98_RS01575	COG1482	cell wall glycoprotein biosynthetic process
DWB98_RS01580	COG1940	carbohydrate kinase activity
DWB98_RS01600	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
DWB98_RS01605	COG0626	cystathionine gamma-synthase activity
DWB98_RS01630	COG0829	nickel cation binding
DWB98_RS01635	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
DWB98_RS01640	COG0830	nickel cation binding
DWB98_RS01645	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
DWB98_RS01650	COG0804	urea catabolic process
DWB98_RS01655	COG0832	Belongs to the urease beta subunit family
DWB98_RS01660	COG0831	urea catabolic process
DWB98_RS01665	COG4413	Urea transporter
DWB98_RS01670	COG0747	negative chemotaxis
DWB98_RS01695	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
DWB98_RS01705	COG0531	amino acid
DWB98_RS01710	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DWB98_RS01720	COG0561	phosphatase activity
DWB98_RS01730	COG0167	dihydroorotate dehydrogenase activity
DWB98_RS01735	COG3001	Fructosamine kinase
DWB98_RS01760	COG0697	spore germination
DWB98_RS01765	COG1113	amino acid transport
DWB98_RS01780	COG3189	MarR family transcriptional regulator
DWB98_RS01795	COG0741	lytic transglycosylase activity
DWB98_RS01800	COG0436	Aminotransferase
DWB98_RS01810	COG2608	mercury ion transmembrane transporter activity
DWB98_RS01815	COG2217	Heavy metal translocating P-type atpase
DWB98_RS01820	COG0659	secondary active sulfate transmembrane transporter activity
DWB98_RS01825	COG1136	(ABC) transporter
DWB98_RS01830	COG0577	efflux transmembrane transporter activity
DWB98_RS01835	COG1028	Short-chain dehydrogenase reductase Sdr
DWB98_RS01840	COG1136	(ABC) transporter
DWB98_RS01865	COG0471	metal ion transport
DWB98_RS01870	COG5505	Protein of unknown function (DUF819)
DWB98_RS01885	COG4336	lyase activity
DWB98_RS01895	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
DWB98_RS01900	COG1012	belongs to the aldehyde dehydrogenase family
DWB98_RS01910	COG2409	Drug exporters of the RND superfamily
DWB98_RS01925	COG1473	amidohydrolase
DWB98_RS01935	COG2819	hydrolase of the alpha beta superfamily
DWB98_RS01950	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
DWB98_RS01960	COG3425	synthase
DWB98_RS01980	COG3942	CHAP domain
DWB98_RS01985	COG1757	Na H antiporter
DWB98_RS01990	COG0583	DNA-binding transcription factor activity
DWB98_RS01995	COG1380	Effector of murein hydrolase LrgA
DWB98_RS02005	COG0028	Belongs to the TPP enzyme family
DWB98_RS02010	COG1288	antiporter activity
DWB98_RS02015	COG1263	PTS System
DWB98_RS02015	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DWB98_RS02015	COG2190	(PTS) system
DWB98_RS02030	COG2515	1-aminocyclopropane-1-carboxylate deaminase
DWB98_RS02050	COG0657	acetylesterase activity
DWB98_RS02055	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DWB98_RS02065	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
DWB98_RS02075	COG2843	Capsule synthesis protein
DWB98_RS02090	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
DWB98_RS02095	COG1063	alcohol dehydrogenase
DWB98_RS02100	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
DWB98_RS02120	COG1129	ABC transporter
DWB98_RS02140	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DWB98_RS02150	COG3764	Sortase (surface protein transpeptidase)
DWB98_RS02155	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
DWB98_RS02160	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
DWB98_RS02170	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DWB98_RS02175	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DWB98_RS02180	COG2249	NAD(P)H dehydrogenase (quinone) activity
DWB98_RS02185	COG0561	phosphatase activity
DWB98_RS02190	COG0778	Nitroreductase
DWB98_RS02195	COG2514	catechol 2,3-dioxygenase activity
DWB98_RS02205	COG1132	(ABC) transporter
DWB98_RS02210	COG1132	(ABC) transporter
DWB98_RS02220	COG0803	Belongs to the bacterial solute-binding protein 9 family
DWB98_RS02225	COG1012	belongs to the aldehyde dehydrogenase family
DWB98_RS02230	COG1846	Transcriptional regulator
DWB98_RS02235	COG0346	lactoylglutathione lyase activity
DWB98_RS02240	COG0346	lactoylglutathione lyase activity
DWB98_RS02245	COG0400	carboxylic ester hydrolase activity
DWB98_RS02255	COG0471	metal ion transport
DWB98_RS02260	COG3949	Membrane
DWB98_RS02270	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
DWB98_RS02275	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DWB98_RS02280	COG0586	Pfam SNARE associated Golgi protein
DWB98_RS02285	COG2271	Major facilitator Superfamily
DWB98_RS02295	COG3527	Alpha-acetolactate decarboxylase
DWB98_RS02300	COG1289	transmembrane transporter activity
DWB98_RS02315	COG4876	unkown
DWB98_RS02320	COG2357	RelA SpoT domain protein
DWB98_RS02330	COG1802	Transcriptional regulator
DWB98_RS02335	COG1070	Carbohydrate kinase
DWB98_RS02340	COG2610	gluconate transmembrane transporter activity
DWB98_RS02345	COG1028	Short-chain dehydrogenase reductase Sdr
DWB98_RS02350	COG3949	Membrane
DWB98_RS02360	COG2211	Major facilitator Superfamily
DWB98_RS02365	COG3250	beta-galactosidase activity
DWB98_RS02380	COG0800	Aldolase
DWB98_RS02385	COG2211	Major facilitator Superfamily
DWB98_RS02390	COG1904	glucuronate isomerase
DWB98_RS02395	COG1312	Catalyzes the dehydration of D-mannonate
DWB98_RS02410	COG4221	oxidoreductase activity
DWB98_RS02440	COG0107	imidazoleglycerol-phosphate synthase activity
DWB98_RS02445	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
DWB98_RS02450	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
DWB98_RS02455	COG0131	Imidazoleglycerol-phosphate dehydratase
DWB98_RS02460	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
DWB98_RS02465	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
DWB98_RS02470	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
DWB98_RS02480	COG3048	D-serine ammonia-lyase activity
DWB98_RS02485	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
DWB98_RS02490	COG0248	Ppx GppA phosphatase
DWB98_RS02495	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
DWB98_RS02500	COG1028	Short-chain dehydrogenase reductase Sdr
DWB98_RS02505	COG1363	Peptidase, m42
DWB98_RS02515	COG0069	glutamate synthase activity
DWB98_RS02525	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
DWB98_RS02530	COG0390	transport system, permease component
DWB98_RS02535	COG2814	Major facilitator Superfamily
DWB98_RS02540	COG2851	Citrate transporter
DWB98_RS02545	COG0531	amino acid
DWB98_RS02550	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
DWB98_RS02555	COG1309	transcriptional regulator
DWB98_RS02560	COG3246	L-lysine catabolic process to acetate
DWB98_RS02565	COG1250	3-hydroxyacyl-CoA dehydrogenase
DWB98_RS02580	COG1174	glycine betaine transport
DWB98_RS02590	COG1174	glycine betaine transport
DWB98_RS02600	COG1346	cytolysis
DWB98_RS02605	COG1380	Effector of murein hydrolase LrgA
DWB98_RS02610	COG3279	Response regulator of the LytR AlgR family
DWB98_RS02615	COG3275	phosphorelay sensor kinase activity
DWB98_RS02625	COG4187	Peptidase family M20/M25/M40
DWB98_RS02645	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
DWB98_RS02655	COG0706	membrane insertase activity
DWB98_RS02660	COG0025	NhaP-type Na H and K H
DWB98_RS02680	COG2814	Major facilitator Superfamily
DWB98_RS02690	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
DWB98_RS02695	COG1388	LysM domain
DWB98_RS02700	COG0588	phosphoglycerate mutase activity
DWB98_RS02710	COG2814	Major facilitator Superfamily
DWB98_RS02725	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
DWB98_RS02730	COG0803	Belongs to the bacterial solute-binding protein 9 family
DWB98_RS02730	COG3443	Belongs to the bacterial solute-binding protein 9 family
DWB98_RS02735	COG2353	YceI-like domain
DWB98_RS02745	COG1695	Transcriptional regulator
DWB98_RS02760	COG2723	6-phospho-beta-galactosidase activity
DWB98_RS02765	COG2190	(PTS) system
DWB98_RS02765	COG1263	PTS System
DWB98_RS02765	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DWB98_RS02770	COG2188	Transcriptional regulator
DWB98_RS02775	COG2116	formate transmembrane transporter activity
DWB98_RS02780	COG0454	-acetyltransferase
DWB98_RS02795	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
DWB98_RS02800	COG2146	nitrite reductase [NAD(P)H] activity
DWB98_RS02825	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
DWB98_RS02830	COG1140	nitrate reductase beta subunit
DWB98_RS02840	COG2181	nitrate reductase activity
DWB98_RS02850	COG4585	Histidine kinase
DWB98_RS02860	COG2223	nitrite transmembrane transporter activity
DWB98_RS02865	COG0071	Belongs to the small heat shock protein (HSP20) family
DWB98_RS02875	COG1846	Transcriptional regulator
DWB98_RS02900	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DWB98_RS02900	COG1263	PTS System
DWB98_RS02920	COG1283	sodium-dependent phosphate transmembrane transporter activity
DWB98_RS02925	COG1028	Short-chain dehydrogenase reductase Sdr
DWB98_RS02930	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DWB98_RS02935	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DWB98_RS02940	COG1288	antiporter activity
DWB98_RS02945	COG1349	DNA-binding transcription factor activity
DWB98_RS02950	COG1063	alcohol dehydrogenase
DWB98_RS02955	COG2376	Dihydroxyacetone kinase
DWB98_RS02965	COG0698	ribose 5-phosphate isomerase
DWB98_RS02975	COG0492	ferredoxin-NADP+ reductase activity
DWB98_RS02985	COG2814	Major facilitator Superfamily
DWB98_RS02990	COG0604	alcohol dehydrogenase
DWB98_RS03010	COG1620	l-lactate permease
DWB98_RS03015	COG0438	transferase activity, transferring glycosyl groups
DWB98_RS03030	COG5002	protein histidine kinase activity
DWB98_RS03030	COG3850	Histidine kinase
DWB98_RS03035	COG0745	RESPONSE REGULATOR receiver
DWB98_RS03040	COG0577	efflux transmembrane transporter activity
DWB98_RS03045	COG1136	(ABC) transporter
DWB98_RS03060	COG4640	response to antibiotic
DWB98_RS03065	COG2814	Major facilitator Superfamily
DWB98_RS03075	COG1566	PFAM secretion protein HlyD family protein
DWB98_RS03080	COG2814	Major facilitator Superfamily
DWB98_RS03105	COG0598	Magnesium transport protein CorA
DWB98_RS03110	COG1304	FMN binding
DWB98_RS03115	COG0786	glutamate:sodium symporter activity
DWB98_RS03120	COG1757	Na H antiporter
DWB98_RS03125	COG2094	Belongs to the DNA glycosylase MPG family
DWB98_RS03130	COG3152	Membrane
DWB98_RS03135	COG1069	ribulokinase activity
DWB98_RS03140	COG4152	abc transporter atp-binding protein
DWB98_RS03145	COG1668	transmembrane transport
DWB98_RS03150	COG2017	converts alpha-aldose to the beta-anomer
DWB98_RS03155	COG2258	MOSC domain
DWB98_RS03160	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
DWB98_RS03165	COG1266	CAAX protease self-immunity
DWB98_RS03170	COG0010	Belongs to the arginase family
DWB98_RS03175	COG0583	DNA-binding transcription factor activity
DWB98_RS03180	COG3314	Sporulation integral membrane protein YlbJ
DWB98_RS03185	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
DWB98_RS03190	COG1228	amidohydrolase
DWB98_RS03195	COG0659	secondary active sulfate transmembrane transporter activity
DWB98_RS03200	COG1473	amidohydrolase
DWB98_RS03205	COG1028	Short-chain dehydrogenase reductase Sdr
DWB98_RS03210	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
DWB98_RS03230	COG1263	PTS System
DWB98_RS03230	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DWB98_RS03240	COG0385	Bile acid
DWB98_RS03245	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DWB98_RS03270	COG1113	amino acid transport
DWB98_RS03275	COG1785	Belongs to the alkaline phosphatase family
DWB98_RS03285	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DWB98_RS03285	COG1263	PTS System
DWB98_RS03290	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
DWB98_RS03315	COG1316	TRANSCRIPTIONal
DWB98_RS03320	COG3383	formate dehydrogenase (NAD+) activity
DWB98_RS03345	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DWB98_RS03350	COG2076	Multidrug Resistance protein
DWB98_RS03355	COG2076	Multidrug Resistance protein
DWB98_RS03360	COG3942	CHAP domain
DWB98_RS03375	COG1757	Na H antiporter
DWB98_RS03380	COG3942	CHAP domain
DWB98_RS03405	COG0765	amino acid transport
DWB98_RS03410	COG0765	amino acid transport
DWB98_RS03415	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DWB98_RS03420	COG1126	abc transporter atp-binding protein
DWB98_RS03425	COG1960	acyl-CoA dehydrogenase activity
DWB98_RS03430	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
DWB98_RS03435	COG1268	BioY protein
DWB98_RS03445	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
DWB98_RS03450	COG1609	Transcriptional regulator
DWB98_RS03455	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
DWB98_RS03460	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
DWB98_RS03465	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
DWB98_RS03470	COG0725	ABC transporter, periplasmic molybdate-binding protein
DWB98_RS03475	COG4149	molybdate abc transporter
DWB98_RS03480	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
DWB98_RS03485	COG1510	regulation of RNA biosynthetic process
DWB98_RS03490	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
DWB98_RS03495	COG0521	Mo-molybdopterin cofactor biosynthetic process
DWB98_RS03500	COG0315	cyclic pyranopterin monophosphate synthase activity
DWB98_RS03525	COG0746	molybdenum cofactor guanylyltransferase activity
DWB98_RS03530	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
DWB98_RS03560	COG2348	transferase activity, transferring amino-acyl groups
DWB98_RS03565	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DWB98_RS03585	COG4975	Glucose uptake
DWB98_RS03595	COG0551	DNA topoisomerase type I activity
DWB98_RS03595	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
DWB98_RS03600	COG2252	PERMEase
DWB98_RS03610	COG0051	transcription antitermination factor activity, RNA binding
DWB98_RS03615	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
DWB98_RS03620	COG0088	Forms part of the polypeptide exit tunnel
DWB98_RS03625	COG0089	rRNA binding
DWB98_RS03630	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
DWB98_RS03635	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
DWB98_RS03640	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
DWB98_RS03645	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
DWB98_RS03650	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
DWB98_RS03655	COG0255	Belongs to the universal ribosomal protein uL29 family
DWB98_RS03660	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
DWB98_RS03665	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
DWB98_RS03670	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
DWB98_RS03675	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
DWB98_RS03680	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
DWB98_RS03685	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
DWB98_RS03690	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
DWB98_RS03695	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
DWB98_RS03700	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
DWB98_RS03705	COG1841	ribosomal large subunit assembly
DWB98_RS03710	COG0200	Binds to the 23S rRNA
DWB98_RS03715	COG0201	protein transport
DWB98_RS03720	COG0563	adenylate kinase activity
DWB98_RS03730	COG0257	Belongs to the bacterial ribosomal protein bL36 family
DWB98_RS03735	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
DWB98_RS03740	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
DWB98_RS03745	COG0202	RNA polymerase activity
DWB98_RS03750	COG0203	ribosomal protein L17
DWB98_RS03755	COG1122	ATPase activity
DWB98_RS03760	COG1122	ATPase activity
DWB98_RS03770	COG0101	tRNA pseudouridine synthase activity
DWB98_RS03775	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
DWB98_RS03780	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
DWB98_RS03790	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DWB98_RS03795	COG2130	NADP-dependent
DWB98_RS03800	COG0604	alcohol dehydrogenase
DWB98_RS03805	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
DWB98_RS03820	COG1302	Protein conserved in bacteria
DWB98_RS03825	COG4264	IucA IucC family
DWB98_RS03830	COG2814	Major facilitator Superfamily
DWB98_RS03835	COG4264	IucA IucC family
DWB98_RS03840	COG3457	Alanine racemase
DWB98_RS03845	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
DWB98_RS03850	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DWB98_RS03855	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DWB98_RS03860	COG3314	Sporulation integral membrane protein YlbJ
DWB98_RS03865	COG2329	Antibiotic biosynthesis monooxygenase
DWB98_RS03875	COG1988	membrane-bound metal-dependent
DWB98_RS03880	COG4284	Utp--glucose-1-phosphate uridylyltransferase
DWB98_RS03885	COG1272	protein, Hemolysin III
DWB98_RS03900	COG0489	protein tyrosine kinase activity
DWB98_RS03955	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
DWB98_RS03965	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DWB98_RS03970	COG0246	Mannitol dehydrogenase
DWB98_RS03980	COG3711	transcriptional antiterminator
DWB98_RS03985	COG2213	PTS system mannitol-specific
DWB98_RS04000	COG1119	ATPase activity
DWB98_RS04030	COG0640	Transcriptional regulator
DWB98_RS04035	COG0702	epimerase
DWB98_RS04040	COG2186	Transcriptional regulator
DWB98_RS04045	COG1482	cell wall glycoprotein biosynthetic process
DWB98_RS04055	COG2855	membrane
DWB98_RS04070	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DWB98_RS04075	COG0783	Belongs to the Dps family
DWB98_RS04080	COG0813	purine-nucleoside phosphorylase activity
DWB98_RS04085	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
DWB98_RS04090	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
DWB98_RS04095	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
DWB98_RS04105	COG1854	S-ribosylhomocysteine lyase activity
DWB98_RS04125	COG5146	pantothenate kinase activity
DWB98_RS04130	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DWB98_RS04140	COG0504	CTP synthase activity
DWB98_RS04145	COG0191	fructose-bisphosphate aldolase activity
DWB98_RS04150	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
DWB98_RS04160	COG1012	belongs to the aldehyde dehydrogenase family
DWB98_RS04165	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
DWB98_RS04170	COG0254	rRNA binding
DWB98_RS04175	COG1435	thymidine kinase activity
DWB98_RS04180	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
DWB98_RS04185	COG2890	protein-(glutamine-N5) methyltransferase activity
DWB98_RS04190	COG0009	L-threonylcarbamoyladenylate synthase
DWB98_RS04195	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DWB98_RS04200	COG4475	Protein of unknown function (DUF436)
DWB98_RS04205	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
DWB98_RS04210	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
DWB98_RS04215	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
DWB98_RS04225	COG0356	it plays a direct role in the translocation of protons across the membrane
DWB98_RS04230	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
DWB98_RS04235	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
DWB98_RS04240	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
DWB98_RS04245	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
DWB98_RS04250	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
DWB98_RS04255	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
DWB98_RS04260	COG0355	proton-transporting ATP synthase activity, rotational mechanism
DWB98_RS04270	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
DWB98_RS04275	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
DWB98_RS04285	COG0629	single-stranded DNA binding
DWB98_RS04290	COG1388	LysM domain
DWB98_RS04295	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
DWB98_RS04305	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
DWB98_RS04310	COG0352	thiamine-phosphate diphosphorylase activity
DWB98_RS04315	COG0706	membrane insertase activity
DWB98_RS04320	COG1418	mRNA catabolic process
DWB98_RS04330	COG1937	Protein conserved in bacteria
DWB98_RS04345	COG0772	Belongs to the SEDS family
DWB98_RS04350	COG1181	Belongs to the D-alanine--D-alanine ligase family
DWB98_RS04355	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
DWB98_RS04360	COG0513	Belongs to the DEAD box helicase family
DWB98_RS04370	COG3428	Bacterial PH domain
DWB98_RS04385	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
DWB98_RS04395	COG2337	Toxic component of a toxin-antitoxin (TA) module
DWB98_RS04400	COG2208	phosphoserine phosphatase activity
DWB98_RS04415	COG1191	sigma factor activity
DWB98_RS04420	COG2183	response to ionizing radiation
DWB98_RS04425	COG3091	SprT-like family
DWB98_RS04455	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
DWB98_RS04460	COG0066	3-isopropylmalate dehydratase activity
DWB98_RS04465	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
DWB98_RS04470	COG0473	3-isopropylmalate dehydrogenase activity
DWB98_RS04475	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DWB98_RS04480	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
DWB98_RS04485	COG0440	acetolactate synthase activity
DWB98_RS04490	COG0028	Belongs to the TPP enzyme family
DWB98_RS04495	COG0129	dihydroxy-acid dehydratase activity
DWB98_RS04500	COG0802	atpase or kinase
DWB98_RS04505	COG1214	PFAM Peptidase M22, glycoprotease
DWB98_RS04510	COG0456	acetyltransferase
DWB98_RS04515	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
DWB98_RS04525	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
DWB98_RS04530	COG0488	(ABC) transporter
DWB98_RS04535	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
DWB98_RS04540	COG2391	methyltransferase activity
DWB98_RS04545	COG0425	Belongs to the sulfur carrier protein TusA family
DWB98_RS04555	COG1609	Transcriptional regulator
DWB98_RS04560	COG1621	beta-fructofuranosidase activity
DWB98_RS04565	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DWB98_RS04570	COG3279	Response regulator of the LytR AlgR family
DWB98_RS04575	COG3290	protein histidine kinase activity
DWB98_RS04585	COG4512	PFAM Accessory gene regulator B
DWB98_RS04590	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DWB98_RS04610	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
DWB98_RS04615	COG0459	protein refolding
DWB98_RS04635	COG1725	Transcriptional regulator
DWB98_RS04650	COG1131	(ABC) transporter
DWB98_RS04695	COG2706	6-phosphogluconolactonase activity
DWB98_RS04700	COG1012	belongs to the aldehyde dehydrogenase family
DWB98_RS04705	COG1227	inorganic diphosphatase activity
DWB98_RS04710	COG1335	isochorismatase
DWB98_RS04720	COG0471	metal ion transport
DWB98_RS04725	COG0077	Prephenate dehydratase
DWB98_RS04735	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
DWB98_RS04740	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
DWB98_RS04745	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
DWB98_RS04755	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
DWB98_RS04760	COG4496	protein, YerC YecD
DWB98_RS04765	COG1876	peptidase activity
DWB98_RS04770	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
DWB98_RS04780	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
DWB98_RS04785	COG4851	CamS sex pheromone cAM373 precursor
DWB98_RS04790	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DWB98_RS04795	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DWB98_RS04800	COG0154	amidase activity
DWB98_RS04805	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DWB98_RS04810	COG1597	lipid kinase activity
DWB98_RS04815	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
DWB98_RS04825	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DWB98_RS04835	COG1528	Iron-storage protein
DWB98_RS04850	COG4129	membrane
DWB98_RS04855	COG0024	Methionine aminopeptidase
DWB98_RS04870	COG4585	Histidine kinase
DWB98_RS04875	COG2197	response regulator
DWB98_RS04880	COG1295	ribonuclease BN
DWB98_RS04890	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DWB98_RS04895	COG4840	Belongs to the UPF0435 family
DWB98_RS04900	COG2309	aminopeptidase activity
DWB98_RS04905	COG1607	acyl-coa hydrolase
DWB98_RS04910	COG0535	radical SAM domain protein
DWB98_RS04920	COG0693	protein deglycase activity
DWB98_RS04925	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DWB98_RS04930	COG2137	regulation of response to DNA damage stimulus
DWB98_RS04940	COG1134	teichoic acid transport
DWB98_RS04950	COG1988	membrane-bound metal-dependent
DWB98_RS04955	COG1194	a g-specific adenine glycosylase
DWB98_RS04960	COG3557	Belongs to the UPF0374 family
DWB98_RS04970	COG4129	membrane
DWB98_RS04975	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
DWB98_RS04980	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
DWB98_RS04985	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DWB98_RS04990	COG0735	belongs to the Fur family
DWB98_RS05130	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
DWB98_RS05145	COG0765	amino acid transport
DWB98_RS05150	COG1126	abc transporter atp-binding protein
DWB98_RS05155	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
DWB98_RS05165	COG0363	glucosamine-6-phosphate deaminase activity
DWB98_RS05180	COG0114	fumarate hydratase activity
DWB98_RS05185	COG0564	pseudouridine synthase activity
DWB98_RS05190	COG2203	Gaf domain
DWB98_RS05190	COG4585	Histidine kinase
DWB98_RS05195	COG2197	response regulator
DWB98_RS05200	COG1301	dicarboxylic acid transport
DWB98_RS05205	COG0772	Belongs to the SEDS family
DWB98_RS05210	COG1316	TRANSCRIPTIONal
DWB98_RS05215	COG0730	response to heat
DWB98_RS05225	COG1682	transport, permease protein
DWB98_RS05240	COG0788	formyltetrahydrofolate deformylase activity
DWB98_RS05250	COG4399	Belongs to the UPF0754 family
DWB98_RS05255	COG3679	Belongs to the UPF0342 family
DWB98_RS05260	COG0420	3'-5' exonuclease activity
DWB98_RS05265	COG4717	serine-type aminopeptidase activity
DWB98_RS05270	COG3481	metal-dependent phosphohydrolase, HD sub domain
DWB98_RS05275	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
DWB98_RS05290	COG0537	adenosine 5'-monophosphoramidase activity
DWB98_RS05295	COG1131	(ABC) transporter
DWB98_RS05300	COG4473	ABC transporter
DWB98_RS05310	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
DWB98_RS05315	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
DWB98_RS05320	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
DWB98_RS05325	COG3545	Serine hydrolase
DWB98_RS05400	COG1028	Short-chain dehydrogenase reductase Sdr
DWB98_RS05420	COG0300	oxidoreductase activity
DWB98_RS05445	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
DWB98_RS05455	COG1506	peptidase
DWB98_RS05460	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
DWB98_RS05465	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
DWB98_RS05475	COG0656	L-ascorbic acid biosynthetic process
DWB98_RS05480	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
DWB98_RS05485	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
DWB98_RS05495	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
DWB98_RS05515	COG1595	DNA-templated transcription, initiation
DWB98_RS05525	COG5632	N-Acetylmuramoyl-L-alanine amidase
DWB98_RS05525	COG3266	domain, Protein
DWB98_RS05525	COG4193	domain, Protein
DWB98_RS05540	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
DWB98_RS05540	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
DWB98_RS05545	COG0307	riboflavin synthase, alpha
DWB98_RS05550	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
DWB98_RS05550	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
DWB98_RS05555	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
DWB98_RS05565	COG2267	carboxylic ester hydrolase activity
DWB98_RS05570	COG0039	L-malate dehydrogenase activity
DWB98_RS05580	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
DWB98_RS05585	COG1242	4 iron, 4 sulfur cluster binding
DWB98_RS05590	COG2814	Major facilitator Superfamily
DWB98_RS05595	COG0495	leucyl-tRNA aminoacylation
DWB98_RS05605	COG2081	HI0933 family
DWB98_RS05610	COG2244	polysaccharide biosynthetic process
DWB98_RS05615	COG1187	pseudouridine synthase activity
DWB98_RS05625	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DWB98_RS05630	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
DWB98_RS05635	COG0510	thiamine kinase activity
DWB98_RS05640	COG0220	tRNA (guanine-N7-)-methyltransferase activity
DWB98_RS05645	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DWB98_RS05655	COG1363	Peptidase, m42
DWB98_RS05660	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DWB98_RS05665	COG4848	Belongs to the UPF0354 family
DWB98_RS05670	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DWB98_RS05675	COG1674	ftsk spoiiie
DWB98_RS05680	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
DWB98_RS05685	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
DWB98_RS05695	COG1605	Chorismate mutase
DWB98_RS05695	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
DWB98_RS05700	COG1609	Transcriptional regulator
DWB98_RS05705	COG0123	including yeast histone deacetylase and acetoin utilization protein
DWB98_RS05710	COG0454	-acetyltransferase
DWB98_RS05715	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DWB98_RS05730	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
DWB98_RS05735	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DWB98_RS05740	COG0204	Acyl-transferase
DWB98_RS05745	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DWB98_RS05745	COG1263	PTS System
DWB98_RS05755	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
DWB98_RS05760	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
DWB98_RS05765	COG1764	response to oxidative stress
DWB98_RS05770	COG0584	glycerophosphoryl diester phosphodiesterase
DWB98_RS05775	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DWB98_RS05780	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
DWB98_RS05790	COG1956	GAF domain-containing protein
DWB98_RS05795	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
DWB98_RS05800	COG1104	cysteine desulfurase activity
DWB98_RS05805	COG0301	tRNA thio-modification
DWB98_RS05815	COG0616	signal peptide processing
DWB98_RS05820	COG1714	RDD family
DWB98_RS05825	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
DWB98_RS05830	COG0827	DNA restriction-modification system
DWB98_RS05835	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
DWB98_RS05845	COG0589	response to stress
DWB98_RS05850	COG0686	Belongs to the AlaDH PNT family
DWB98_RS05855	COG3142	Participates in the control of copper homeostasis
DWB98_RS05860	COG0006	proline dipeptidase activity
DWB98_RS05865	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
DWB98_RS05875	COG4109	DRTGG domain
DWB98_RS05880	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
DWB98_RS05885	COG0587	DNA-directed DNA polymerase activity
DWB98_RS05890	COG0281	malic enzyme
DWB98_RS05895	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
DWB98_RS05900	COG0825	malonyl-CoA metabolic process
DWB98_RS05905	COG0205	6-phosphofructokinase activity
DWB98_RS05910	COG0469	pyruvate kinase activity
DWB98_RS05920	COG1113	amino acid transport
DWB98_RS05925	COG0372	Belongs to the citrate synthase family
DWB98_RS05930	COG0538	isocitrate dehydrogenase activity
DWB98_RS05935	COG0745	RESPONSE REGULATOR receiver
DWB98_RS05940	COG5002	protein histidine kinase activity
DWB98_RS05945	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DWB98_RS05945	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DWB98_RS05955	COG0237	dephospho-CoA kinase activity
DWB98_RS05960	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
DWB98_RS05965	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
DWB98_RS05975	COG1484	DNA-dependent DNA replication
DWB98_RS05980	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
DWB98_RS05985	COG0833	amino acid
DWB98_RS05990	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
DWB98_RS05995	COG0291	Belongs to the bacterial ribosomal protein bL35 family
DWB98_RS06000	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
DWB98_RS06005	COG4112	unkown
DWB98_RS06015	COG0544	peptidyl-prolyl cis-trans isomerase activity
DWB98_RS06020	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
DWB98_RS06025	COG0218	Necessary for normal cell division and for the maintenance of normal septation
DWB98_RS06030	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
DWB98_RS06035	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
DWB98_RS06040	COG0181	hydroxymethylbilane synthase activity
DWB98_RS06050	COG0113	porphobilinogen synthase activity
DWB98_RS06055	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
DWB98_RS06065	COG2818	Glycosylase
DWB98_RS06070	COG0525	valine-tRNA ligase activity
DWB98_RS06075	COG0285	dihydrofolate synthase activity
DWB98_RS06090	COG2003	Belongs to the UPF0758 family
DWB98_RS06115	COG0261	This protein binds to 23S rRNA in the presence of protein L20
DWB98_RS06120	COG2868	ribosomal protein
DWB98_RS06125	COG0211	Belongs to the bacterial ribosomal protein bL27 family
DWB98_RS06130	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
DWB98_RS06135	COG4492	Belongs to the UPF0735 family
DWB98_RS06140	COG0632	four-way junction helicase activity
DWB98_RS06145	COG2255	four-way junction helicase activity
DWB98_RS06150	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
DWB98_RS06155	COG0343	queuine tRNA-ribosyltransferase activity
DWB98_RS06160	COG1862	Preprotein translocase
DWB98_RS06165	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DWB98_RS06165	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DWB98_RS06170	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
DWB98_RS06170	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
DWB98_RS06180	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
DWB98_RS06185	COG1490	D-aminoacyl-tRNA deacylase activity
DWB98_RS06190	COG0860	N-Acetylmuramoyl-L-alanine amidase
DWB98_RS06195	COG0124	histidyl-tRNA synthetase
DWB98_RS06200	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
DWB98_RS06210	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
DWB98_RS06215	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
DWB98_RS06220	COG1959	2 iron, 2 sulfur cluster binding
DWB98_RS06230	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DWB98_RS06235	COG0488	(ABC) transporter
DWB98_RS06240	COG1104	cysteine desulfurase activity
DWB98_RS06245	COG0482	sulfurtransferase activity
DWB98_RS06255	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
DWB98_RS06260	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
DWB98_RS06265	COG4472	Bacterial protein of unknown function (DUF965)
DWB98_RS06270	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
DWB98_RS06275	COG3906	Belongs to the UPF0473 family
DWB98_RS06280	COG4122	O-methyltransferase activity
DWB98_RS06285	COG0826	peptidase U32
DWB98_RS06290	COG0826	peptidase U32
DWB98_RS06295	COG0572	uridine kinase
DWB98_RS06300	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
DWB98_RS06305	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
DWB98_RS06310	COG1984	allophanate hydrolase subunit 2
DWB98_RS06315	COG0508	dehydrogenase complex catalyzes the overall conversion of
DWB98_RS06320	COG0439	Biotin carboxylase
DWB98_RS06325	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
DWB98_RS06330	COG1914	H( )-stimulated, divalent metal cation uptake system
DWB98_RS06335	COG0730	response to heat
DWB98_RS06340	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
DWB98_RS06345	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
DWB98_RS06350	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
DWB98_RS06355	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
DWB98_RS06360	COG1534	Rna-binding protein
DWB98_RS06365	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
DWB98_RS06370	COG1713	HD superfamily hydrolase involved in NAD metabolism
DWB98_RS06375	COG0799	negative regulation of ribosome biogenesis
DWB98_RS06380	COG2226	methyltransferase
DWB98_RS06385	COG1555	photosystem II stabilization
DWB98_RS06385	COG1596	polysaccharide export
DWB98_RS06390	COG2131	deaminase
DWB98_RS06395	COG2333	competence protein COMEC
DWB98_RS06395	COG0658	competence protein
DWB98_RS06400	COG1466	dna polymerase III delta subunit
DWB98_RS06405	COG0268	Binds directly to 16S ribosomal RNA
DWB98_RS06410	COG0481	GTPase activity
DWB98_RS06415	COG0635	Involved in the biosynthesis of porphyrin-containing compound
DWB98_RS06420	COG1420	regulation of RNA biosynthetic process
DWB98_RS06425	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
DWB98_RS06430	COG0443	Heat shock 70 kDa protein
DWB98_RS06435	COG0484	heat shock protein binding
DWB98_RS06440	COG2264	protein methyltransferase activity
DWB98_RS06445	COG1385	rRNA (uridine-N3-)-methyltransferase activity
DWB98_RS06450	COG0828	Belongs to the bacterial ribosomal protein bS21 family
DWB98_RS06455	COG1030	water channel activity
DWB98_RS06460	COG4864	UPF0365 protein
DWB98_RS06470	COG1702	phosphate starvation-inducible protein PhoH
DWB98_RS06475	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
DWB98_RS06480	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
DWB98_RS06485	COG0295	cytidine deaminase activity
DWB98_RS06490	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
DWB98_RS06495	COG1381	Involved in DNA repair and RecF pathway recombination
DWB98_RS06500	COG0423	glycine-tRNA ligase activity
DWB98_RS06505	COG0517	IMP dehydrogenase activity
DWB98_RS06510	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
DWB98_RS06520	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
DWB98_RS06525	COG2384	SAM-dependent methyltransferase
DWB98_RS06535	COG0513	Belongs to the DEAD box helicase family
DWB98_RS06540	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
DWB98_RS06545	COG1121	(ABC) transporter
DWB98_RS06550	COG1108	ABC-type Mn2 Zn2 transport systems permease components
DWB98_RS06560	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
DWB98_RS06565	COG0768	penicillin binding
DWB98_RS06570	COG0267	Belongs to the bacterial ribosomal protein bL33 family
DWB98_RS06575	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
DWB98_RS06580	COG0457	Tetratricopeptide repeat
DWB98_RS06580	COG0705	Rhomboid family
DWB98_RS06585	COG4483	Protein conserved in bacteria
DWB98_RS06590	COG1940	carbohydrate kinase activity
DWB98_RS06595	COG0011	TIGRFAM Protein of
DWB98_RS06600	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DWB98_RS06605	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
DWB98_RS06640	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
DWB98_RS06645	COG0404	The glycine cleavage system catalyzes the degradation of glycine
DWB98_RS06650	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
DWB98_RS06655	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
DWB98_RS06660	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
DWB98_RS06665	COG0095	Lipoate-protein ligase
DWB98_RS06680	COG0006	proline dipeptidase activity
DWB98_RS06685	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
DWB98_RS06690	COG0511	ligase activity, forming carbon-carbon bonds
DWB98_RS06695	COG0439	Biotin carboxylase
DWB98_RS06700	COG1302	Protein conserved in bacteria
DWB98_RS06705	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
DWB98_RS06710	COG1570	exodeoxyribonuclease VII activity
DWB98_RS06715	COG1722	exodeoxyribonuclease VII activity
DWB98_RS06725	COG1438	arginine binding
DWB98_RS06730	COG0497	DNA recombination
DWB98_RS06735	COG0280	phosphate acetyltransferase
DWB98_RS06740	COG3426	butyrate kinase activity
DWB98_RS06745	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DWB98_RS06750	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
DWB98_RS06755	COG0022	dehydrogenase e1 component
DWB98_RS06760	COG0508	dehydrogenase complex catalyzes the overall conversion of
DWB98_RS06780	COG4129	membrane
DWB98_RS06785	COG2195	Cleaves the N-terminal amino acid of tripeptides
DWB98_RS06795	COG1609	Transcriptional regulator
DWB98_RS06800	COG0366	Alpha amylase catalytic
DWB98_RS06810	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
DWB98_RS06815	COG1234	tRNA 3'-trailer cleavage
DWB98_RS06820	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
DWB98_RS06830	COG0667	Aldo Keto reductase
DWB98_RS06835	COG0494	nUDIX hydrolase
DWB98_RS06840	COG0735	belongs to the Fur family
DWB98_RS06845	COG4974	Belongs to the 'phage' integrase family
DWB98_RS06855	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
DWB98_RS06860	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
DWB98_RS06865	COG1187	pseudouridine synthase activity
DWB98_RS06870	COG0745	RESPONSE REGULATOR receiver
DWB98_RS06885	COG1141	Ferredoxin
DWB98_RS06895	COG0514	ATP-dependent DNA helicase (RecQ)
DWB98_RS06900	COG1388	LysM domain
DWB98_RS06905	COG0492	ferredoxin-NADP+ reductase activity
DWB98_RS06915	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
DWB98_RS06920	COG0539	negative regulation of cytoplasmic translation
DWB98_RS06925	COG1160	GTP binding
DWB98_RS06930	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
DWB98_RS06945	COG2226	methyltransferase
DWB98_RS06950	COG0142	geranyltranstransferase activity
DWB98_RS06955	COG0105	UTP biosynthetic process
DWB98_RS06960	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
DWB98_RS06965	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
DWB98_RS06970	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
DWB98_RS06980	COG5582	Belongs to the UPF0302 family
DWB98_RS06985	COG4347	Protein of unknown function (DUF1405)
DWB98_RS06990	COG2738	Putative neutral zinc metallopeptidase
DWB98_RS06995	COG1694	Mazg nucleotide pyrophosphohydrolase
DWB98_RS07000	COG0438	transferase activity, transferring glycosyl groups
DWB98_RS07005	COG0617	tRNA 3'-terminal CCA addition
DWB98_RS07015	COG1199	ATP-dependent helicase activity
DWB98_RS07015	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
DWB98_RS07020	COG0017	Asparaginyl-tRNA synthetase
DWB98_RS07025	COG3935	DnaD domain protein
DWB98_RS07030	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
DWB98_RS07040	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DWB98_RS07040	COG4499	WXG100 protein secretion system (Wss), protein YukC
DWB98_RS07045	COG3331	DNA recombination
DWB98_RS07055	COG4474	Belongs to the UPF0398 family
DWB98_RS07070	COG0116	Belongs to the methyltransferase superfamily
DWB98_RS07075	COG2962	Rard protein
DWB98_RS07085	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
DWB98_RS07090	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DWB98_RS07100	COG3545	Serine hydrolase
DWB98_RS07105	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
DWB98_RS07115	COG1413	lyase activity
DWB98_RS07120	COG1413	lyase activity
DWB98_RS07130	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
DWB98_RS07150	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DWB98_RS07160	COG4479	Belongs to the UPF0346 family
DWB98_RS07165	COG0793	Belongs to the peptidase S41A family
DWB98_RS07175	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
DWB98_RS07180	COG0671	phosphoesterase, PA-phosphatase related
DWB98_RS07185	COG0745	RESPONSE REGULATOR receiver
DWB98_RS07190	COG5002	protein histidine kinase activity
DWB98_RS07195	COG0567	Dehydrogenase, E1 component
DWB98_RS07200	COG0508	dehydrogenase complex catalyzes the overall conversion of
DWB98_RS07210	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
DWB98_RS07220	COG1917	Cupin 2, conserved barrel domain protein
DWB98_RS07220	COG2207	Transcriptional regulator
DWB98_RS07245	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
DWB98_RS07250	COG1121	(ABC) transporter
DWB98_RS07275	COG0714	Associated with various cellular activities
DWB98_RS07280	COG4548	von Willebrand factor, type A
DWB98_RS07285	COG1114	Component of the transport system for branched-chain amino acids
DWB98_RS07290	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
DWB98_RS07295	COG3853	Toxic anion resistance protein (TelA)
DWB98_RS07305	COG1254	Belongs to the acylphosphatase family
DWB98_RS07315	COG1278	Cold shock
DWB98_RS07330	COG1473	amidohydrolase
DWB98_RS07340	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
DWB98_RS07345	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DWB98_RS07350	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
DWB98_RS07355	COG0527	aspartate kinase activity
DWB98_RS07365	COG0488	(ABC) transporter
DWB98_RS07370	COG2996	Protein conserved in bacteria
DWB98_RS07375	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
DWB98_RS07380	COG0573	inorganic phosphate transmembrane transporter activity
DWB98_RS07385	COG0581	inorganic phosphate transmembrane transporter activity
DWB98_RS07390	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
DWB98_RS07400	COG1164	Oligoendopeptidase f
DWB98_RS07410	COG4607	ABC-type enterochelin transport system periplasmic component
DWB98_RS07425	COG2348	transferase activity, transferring amino-acyl groups
DWB98_RS07435	COG0159	tryptophan synthase activity
DWB98_RS07440	COG0133	tryptophan synthase activity
DWB98_RS07450	COG0134	indole-3-glycerol-phosphate synthase activity
DWB98_RS07455	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
DWB98_RS07460	COG0512	Glutamine amidotransferase of anthranilate synthase
DWB98_RS07465	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
DWB98_RS07485	COG0640	Transcriptional regulator
DWB98_RS07495	COG0438	transferase activity, transferring glycosyl groups
DWB98_RS07500	COG1280	lysine exporter protein (LysE YggA)
DWB98_RS07515	COG1363	Peptidase, m42
DWB98_RS07525	COG0287	Prephenate dehydrogenase
DWB98_RS07530	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DWB98_RS07535	COG1942	4-Oxalocrotonate Tautomerase
DWB98_RS07550	COG1879	ABC-type sugar transport system periplasmic component
DWB98_RS07555	COG1172	Belongs to the binding-protein-dependent transport system permease family
DWB98_RS07560	COG1129	ABC transporter
DWB98_RS07565	COG1869	D-ribose catabolic process
DWB98_RS07570	COG1609	Transcriptional regulator
DWB98_RS07580	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
DWB98_RS07580	COG0392	lysyltransferase activity
DWB98_RS07585	COG0628	permease
DWB98_RS07595	COG3711	transcriptional antiterminator
DWB98_RS07600	COG1115	amino acid carrier protein
DWB98_RS07605	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
DWB98_RS07615	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
DWB98_RS07620	COG4841	protein insertion into membrane
DWB98_RS07625	COG0824	Thioesterase
DWB98_RS07630	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
DWB98_RS07635	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
DWB98_RS07640	COG1970	mechanosensitive ion channel activity
DWB98_RS07645	COG0419	ATPase involved in DNA repair
DWB98_RS07650	COG0420	3'-5' exonuclease activity
DWB98_RS07655	COG4846	Membrane protein involved in cytochrome C biogenesis
DWB98_RS07665	COG3763	UPF0154 protein
DWB98_RS07685	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
DWB98_RS07695	COG0516	GMP reductase activity
DWB98_RS07700	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
DWB98_RS07705	COG0267	Belongs to the bacterial ribosomal protein bL33 family
DWB98_RS07710	COG0753	catalase activity
DWB98_RS07715	COG0833	amino acid
DWB98_RS07725	COG0561	phosphatase activity
DWB98_RS07730	COG0083	homoserine kinase activity
DWB98_RS07735	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
DWB98_RS07740	COG0460	homoserine dehydrogenase
DWB98_RS07745	COG0527	aspartate kinase activity
DWB98_RS07775	COG2197	response regulator
DWB98_RS07780	COG4585	Histidine kinase
DWB98_RS07785	COG0842	Transport permease protein
DWB98_RS07790	COG1131	(ABC) transporter
DWB98_RS07800	COG2808	Putative FMN-binding domain
DWB98_RS07805	COG1764	response to oxidative stress
DWB98_RS07815	COG0789	Transcriptional regulator
DWB98_RS07820	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
DWB98_RS07825	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
DWB98_RS07830	COG0386	Belongs to the glutathione peroxidase family
DWB98_RS07835	COG1923	regulation of RNA biosynthetic process
DWB98_RS07840	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
DWB98_RS07850	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
DWB98_RS07855	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
DWB98_RS07860	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
DWB98_RS07865	COG1619	proteins homologs of microcin C7 resistance protein MccF
DWB98_RS07875	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
DWB98_RS07880	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
DWB98_RS07890	COG4550	Control of competence regulator ComK, YlbF/YmcA
DWB98_RS07895	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
DWB98_RS07910	COG1959	2 iron, 2 sulfur cluster binding
DWB98_RS07920	COG1013	pyruvate-flavodoxin oxidoreductase activity
DWB98_RS07925	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
DWB98_RS07925	COG0674	pyruvate-flavodoxin oxidoreductase activity
DWB98_RS07930	COG1692	metallophosphoesterase
DWB98_RS07940	COG1418	mRNA catabolic process
DWB98_RS07945	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
DWB98_RS07950	COG1058	Belongs to the CinA family
DWB98_RS07950	COG1546	Belongs to the CinA family
DWB98_RS07970	COG0300	oxidoreductase activity
DWB98_RS07975	COG0612	Peptidase, M16
DWB98_RS07980	COG0612	Peptidase, M16
DWB98_RS07985	COG2188	Transcriptional regulator
DWB98_RS07990	COG1674	ftsk spoiiie
DWB98_RS07995	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
DWB98_RS08000	COG1185	polyribonucleotide nucleotidyltransferase activity
DWB98_RS08005	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
DWB98_RS08010	COG0196	riboflavin kinase activity
DWB98_RS08015	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
DWB98_RS08020	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
DWB98_RS08035	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
DWB98_RS08040	COG1358	cellular component organization or biogenesis
DWB98_RS08045	COG2740	Nucleic-acid-binding protein implicated in transcription termination
DWB98_RS08050	COG0195	Participates in both transcription termination and antitermination
DWB98_RS08055	COG0779	Required for maturation of 30S ribosomal subunits
DWB98_RS08060	COG2176	DNA-directed DNA polymerase activity
DWB98_RS08065	COG0442	prolyl-tRNA aminoacylation
DWB98_RS08075	COG4589	Belongs to the CDS family
DWB98_RS08080	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
DWB98_RS08085	COG0233	cytoplasmic translational termination
DWB98_RS08090	COG0528	UMP kinase activity
DWB98_RS08095	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
DWB98_RS08100	COG0052	Belongs to the universal ribosomal protein uS2 family
DWB98_RS08105	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
DWB98_RS08110	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
DWB98_RS08115	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
DWB98_RS08120	COG4974	Belongs to the 'phage' integrase family
DWB98_RS08125	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
DWB98_RS08130	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
DWB98_RS08135	COG0758	DNA mediated transformation
DWB98_RS08145	COG0045	succinate-CoA ligase (ADP-forming) activity
DWB98_RS08150	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
DWB98_RS08160	COG4485	Bacterial membrane protein, YfhO
DWB98_RS08170	COG0335	large ribosomal subunit rRNA binding
DWB98_RS08175	COG0336	Belongs to the RNA methyltransferase TrmD family
DWB98_RS08180	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
DWB98_RS08185	COG0228	four-way junction DNA binding
DWB98_RS08190	COG1028	Short-chain dehydrogenase reductase Sdr
DWB98_RS08195	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DWB98_RS08200	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
DWB98_RS08205	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
DWB98_RS08210	COG0552	protein localization to endoplasmic reticulum
DWB98_RS08215	COG1196	nuclear chromosome segregation
DWB98_RS08220	COG0571	ribonuclease III activity
DWB98_RS08225	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DWB98_RS08240	COG0416	fatty acid biosynthetic process
DWB98_RS08245	COG1349	DNA-binding transcription factor activity
DWB98_RS08255	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
DWB98_RS08260	COG1760	l-serine dehydratase
DWB98_RS08265	COG1760	l-serine dehydratase
DWB98_RS08270	COG1461	Dihydroxyacetone kinase
DWB98_RS08275	COG1302	Protein conserved in bacteria
DWB98_RS08280	COG0227	Belongs to the bacterial ribosomal protein bL28 family
DWB98_RS08285	COG1564	THIamine pyrophosphokinase
DWB98_RS08290	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
DWB98_RS08295	COG1162	GTPase activity
DWB98_RS08310	COG0820	rRNA (adenine-C2-)-methyltransferase activity
DWB98_RS08315	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
DWB98_RS08315	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
DWB98_RS08320	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
DWB98_RS08325	COG0242	peptide deformylase activity
DWB98_RS08340	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
DWB98_RS08345	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
DWB98_RS08350	COG1758	RNA polymerase activity
DWB98_RS08355	COG0194	GDP metabolic process
DWB98_RS08360	COG1293	RNA-binding protein homologous to eukaryotic snRNP
DWB98_RS08380	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DWB98_RS08390	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
DWB98_RS08395	COG0284	orotidine-5'-phosphate decarboxylase activity
DWB98_RS08400	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
DWB98_RS08405	COG0505	Belongs to the CarA family
DWB98_RS08415	COG0540	Belongs to the ATCase OTCase family
DWB98_RS08425	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
DWB98_RS08430	COG0564	pseudouridine synthase activity
DWB98_RS08435	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
DWB98_RS08445	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
DWB98_RS08450	COG3599	regulation of cell shape
DWB98_RS08460	COG0762	integral membrane protein
DWB98_RS08465	COG1799	cell septum assembly
DWB98_RS08470	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
DWB98_RS08475	COG1496	oxidoreductase activity
DWB98_RS08480	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
DWB98_RS08485	COG0849	cell division
DWB98_RS08495	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
DWB98_RS08500	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DWB98_RS08505	COG0768	penicillin binding
DWB98_RS08510	COG4839	cell division protein FtsL
DWB98_RS08515	COG0275	rRNA processing
DWB98_RS08520	COG2001	Belongs to the MraZ family
DWB98_RS08525	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
DWB98_RS08530	COG0454	-acetyltransferase
DWB98_RS08535	COG1011	Hydrolase
DWB98_RS08570	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
DWB98_RS08575	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
DWB98_RS08580	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
DWB98_RS08585	COG1053	succinate dehydrogenase
DWB98_RS08590	COG2009	succinate dehydrogenase
DWB98_RS08595	COG0322	excinuclease ABC activity
DWB98_RS08600	COG3118	belongs to the thioredoxin family
DWB98_RS08605	COG1193	negative regulation of DNA recombination
DWB98_RS08610	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
DWB98_RS08610	COG1796	DNA polymerase
DWB98_RS08620	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
DWB98_RS08625	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
DWB98_RS08630	COG0072	phenylalanine-tRNA ligase activity
DWB98_RS08635	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
DWB98_RS08640	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DWB98_RS08650	COG0333	Belongs to the bacterial ribosomal protein bL32 family
DWB98_RS08660	COG1323	Belongs to the UPF0348 family
DWB98_RS08665	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
DWB98_RS08670	COG0742	ribosomal rna small subunit methyltransferase
DWB98_RS08680	COG4471	UPF0298 protein
DWB98_RS08685	COG0584	glycerophosphoryl diester phosphodiesterase
DWB98_RS08690	COG3679	Belongs to the UPF0342 family
DWB98_RS08710	COG0109	protoheme IX farnesyltransferase activity
DWB98_RS08715	COG1612	heme a metabolic process
DWB98_RS08725	COG0772	Belongs to the SEDS family
DWB98_RS08730	COG4838	Belongs to the UPF0358 family
DWB98_RS08735	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
DWB98_RS08740	COG4896	Protein conserved in bacteria
DWB98_RS08745	COG1217	gtp-binding protein TYPA
DWB98_RS08755	COG0483	inositol monophosphate 1-phosphatase activity
DWB98_RS08760	COG4493	Belongs to the UPF0637 family
DWB98_RS08770	COG1914	H( )-stimulated, divalent metal cation uptake system
DWB98_RS08785	COG1177	transmembrane transport
DWB98_RS08790	COG1176	ABC-type spermidine putrescine transport system, permease component I
DWB98_RS08795	COG3842	ATPase activity
DWB98_RS08805	COG4476	Belongs to the UPF0223 family
DWB98_RS08835	COG0242	peptide deformylase activity
DWB98_RS08845	COG5503	Protein of unknown function (DUF1447)
DWB98_RS08850	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
DWB98_RS08855	COG0569	domain protein
DWB98_RS08860	COG1294	oxidase, subunit
DWB98_RS08865	COG1271	oxidase subunit
DWB98_RS08875	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DWB98_RS08880	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
DWB98_RS08890	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
DWB98_RS08905	COG4172	Belongs to the ABC transporter superfamily
DWB98_RS08915	COG0151	Belongs to the GarS family
DWB98_RS08920	COG0138	bifunctional purine biosynthesis protein purh
DWB98_RS08930	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
DWB98_RS08940	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
DWB98_RS08945	COG0047	phosphoribosylformylglycinamidine synthase activity
DWB98_RS08950	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
DWB98_RS08955	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
DWB98_RS08960	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
DWB98_RS08965	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
DWB98_RS08970	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
DWB98_RS08975	COG1017	nitric oxide dioxygenase activity
DWB98_RS08975	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
DWB98_RS08985	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
DWB98_RS08990	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
DWB98_RS08995	COG1845	cytochrome c oxidase, subunit III
DWB98_RS09000	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
DWB98_RS09015	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DWB98_RS09020	COG1316	TRANSCRIPTIONal
DWB98_RS09045	COG3594	Acyltransferase
DWB98_RS09050	COG0436	Aminotransferase
DWB98_RS09055	COG1846	Transcriptional regulator
DWB98_RS09060	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
DWB98_RS09065	COG2267	carboxylic ester hydrolase activity
DWB98_RS09070	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
DWB98_RS09075	COG1169	isochorismate synthase
DWB98_RS09080	COG1575	Belongs to the MenA family. Type 1 subfamily
DWB98_RS09090	COG2314	TM2 domain
DWB98_RS09100	COG2807	transmembrane transport
DWB98_RS09165	COG4903	ComK protein
DWB98_RS09180	COG4873	Protein conserved in bacteria
DWB98_RS09190	COG0737	Belongs to the 5'-nucleotidase family
DWB98_RS09195	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
DWB98_RS09200	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DWB98_RS09205	COG0861	Integral membrane protein TerC family
DWB98_RS09210	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
DWB98_RS09220	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
DWB98_RS09225	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
DWB98_RS09230	COG2814	Major facilitator Superfamily
DWB98_RS09235	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
DWB98_RS09240	COG2382	esterase
DWB98_RS09245	COG1115	amino acid carrier protein
DWB98_RS09250	COG0628	permease
DWB98_RS09260	COG0475	glutathione-regulated potassium exporter activity
DWB98_RS09260	COG0569	domain protein
DWB98_RS09265	COG2239	Acts as a magnesium transporter
DWB98_RS09270	COG0564	pseudouridine synthase activity
DWB98_RS09275	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
DWB98_RS09280	COG2357	RelA SpoT domain protein
DWB98_RS09295	COG2346	COG2346, Truncated hemoglobins
DWB98_RS09300	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
DWB98_RS09305	COG1164	Oligoendopeptidase f
DWB98_RS09315	COG4862	establishment of competence for transformation
DWB98_RS09320	COG1393	Belongs to the ArsC family
DWB98_RS09325	COG0180	Tryptophanyl-tRNA synthetase
DWB98_RS09330	COG4166	transmembrane transport
DWB98_RS09335	COG4608	Belongs to the ABC transporter superfamily
DWB98_RS09340	COG0444	Belongs to the ABC transporter superfamily
DWB98_RS09345	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DWB98_RS09350	COG0601	transmembrane transport
DWB98_RS09370	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DWB98_RS09395	COG0561	phosphatase activity
DWB98_RS09400	COG0446	pyridine nucleotide-disulphide oxidoreductase
DWB98_RS09410	COG0179	Fumarylacetoacetate (FAA) hydrolase
DWB98_RS09415	COG2311	Membrane
DWB98_RS09420	COG1074	ATP-dependent DNA helicase activity
DWB98_RS09425	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
DWB98_RS09440	COG0398	Pfam SNARE associated Golgi protein
DWB98_RS09445	COG0166	Belongs to the GPI family
DWB98_RS09450	COG0137	argininosuccinate synthase activity
DWB98_RS09455	COG0165	Argininosuccinate lyase
DWB98_RS09460	COG0584	glycerophosphoryl diester phosphodiesterase
DWB98_RS09470	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
DWB98_RS09475	COG1902	pentaerythritol trinitrate reductase activity
DWB98_RS09480	COG1098	S1 RNA binding domain
DWB98_RS09485	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
DWB98_RS09495	COG2111	Na H antiporter
DWB98_RS09495	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
DWB98_RS09500	COG2111	Na H antiporter
DWB98_RS09505	COG1006	Multisubunit Na H antiporter MnhC subunit
DWB98_RS09510	COG0651	ATP synthesis coupled electron transport
DWB98_RS09515	COG1863	multisubunit Na H antiporter MnhE subunit
DWB98_RS09520	COG2212	antiporter activity
DWB98_RS09525	COG1320	monovalent cation:proton antiporter activity
DWB98_RS09535	COG2050	protein possibly involved in aromatic compounds catabolism
DWB98_RS09540	COG2056	Na+-H+ antiporter family
DWB98_RS09545	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
DWB98_RS09550	COG1252	NADH dehydrogenase
DWB98_RS09555	COG0316	Belongs to the HesB IscA family
DWB98_RS09560	COG4844	belongs to the
DWB98_RS09565	COG1252	NADH dehydrogenase
DWB98_RS09570	COG4837	Protein of unknown function (DUF1462)
DWB98_RS09575	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
DWB98_RS09580	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
DWB98_RS09585	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DWB98_RS09590	COG1696	Membrane protein involved in D-alanine export
DWB98_RS09595	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DWB98_RS09605	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DWB98_RS09610	COG0647	UMP catabolic process
DWB98_RS09615	COG2445	Protein of unknown function DUF86
DWB98_RS09625	COG4470	Protein conserved in bacteria
DWB98_RS09630	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
DWB98_RS09635	COG0737	Belongs to the 5'-nucleotidase family
DWB98_RS09640	COG0730	response to heat
DWB98_RS09645	COG1801	Protein of unknown function DUF72
DWB98_RS09650	COG2070	2-Nitropropane dioxygenase
DWB98_RS09655	COG1253	flavin adenine dinucleotide binding
DWB98_RS09665	COG0454	-acetyltransferase
DWB98_RS09670	COG0719	Fe-S assembly protein
DWB98_RS09675	COG0822	iron-sulfur transferase activity
DWB98_RS09680	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
DWB98_RS09685	COG0719	Fe-S assembly protein
DWB98_RS09690	COG0396	ATPase activity
DWB98_RS09700	COG1253	flavin adenine dinucleotide binding
DWB98_RS09710	COG1464	Belongs to the NlpA lipoprotein family
DWB98_RS09715	COG2011	ABC-type metal ion transport system permease component
DWB98_RS09720	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
DWB98_RS09725	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DWB98_RS09730	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
DWB98_RS09735	COG0509	glycine decarboxylation via glycine cleavage system
DWB98_RS09740	COG1393	Belongs to the ArsC family
DWB98_RS09745	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DWB98_RS09750	COG0778	Nitroreductase
DWB98_RS09755	COG0710	3-dehydroquinate dehydratase activity
DWB98_RS09760	COG1764	response to oxidative stress
DWB98_RS09775	COG2851	Citrate transporter
DWB98_RS09790	COG2314	TM2 domain
DWB98_RS09820	COG2153	protein acetylation
DWB98_RS09825	COG0346	lactoylglutathione lyase activity
DWB98_RS09840	COG1073	alpha beta
DWB98_RS09875	COG0346	lactoylglutathione lyase activity
DWB98_RS09905	COG0346	lactoylglutathione lyase activity
DWB98_RS10035	COG3620	sequence-specific DNA binding
DWB98_RS10055	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
DWB98_RS10060	COG0557	exoribonuclease II activity
DWB98_RS10065	COG1647	Serine aminopeptidase, S33
DWB98_RS10070	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
DWB98_RS10080	COG0148	phosphopyruvate hydratase activity
DWB98_RS10085	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
DWB98_RS10090	COG0149	triose-phosphate isomerase activity
DWB98_RS10095	COG0126	phosphoglycerate kinase activity
DWB98_RS10120	COG1090	epimerase
DWB98_RS10130	COG0740	serine-type endopeptidase activity
DWB98_RS10140	COG1481	regulation of sporulation
DWB98_RS10145	COG0391	Required for morphogenesis under gluconeogenic growth conditions
DWB98_RS10150	COG1660	Displays ATPase and GTPase activities
DWB98_RS10155	COG0492	ferredoxin-NADP+ reductase activity
DWB98_RS10165	COG0110	maltose O-acetyltransferase activity
DWB98_RS10170	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
DWB98_RS10175	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
DWB98_RS10185	COG0556	nucleotide-excision repair
DWB98_RS10200	COG3942	CHAP domain
DWB98_RS10200	COG1388	LysM domain
DWB98_RS10210	COG0653	protein targeting
DWB98_RS10215	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
DWB98_RS10220	COG1040	competence protein
DWB98_RS10225	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
DWB98_RS10235	COG1739	Uncharacterized protein family UPF0029
DWB98_RS10240	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DWB98_RS10245	COG2199	diguanylate cyclase activity
DWB98_RS10260	COG2195	Cleaves the N-terminal amino acid of tripeptides
DWB98_RS10265	COG1929	Belongs to the glycerate kinase type-1 family
DWB98_RS10285	COG0812	UDP-N-acetylmuramate dehydrogenase activity
DWB98_RS10300	COG4607	ABC-type enterochelin transport system periplasmic component
DWB98_RS10305	COG4604	ABC transporter, ATP-binding protein
DWB98_RS10310	COG4605	iron ion homeostasis
DWB98_RS10315	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DWB98_RS10320	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DWB98_RS10325	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DWB98_RS10330	COG1780	Probably involved in ribonucleotide reductase function
DWB98_RS10340	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
DWB98_RS10345	COG3104	oligopeptide transport
DWB98_RS10350	COG3104	oligopeptide transport
DWB98_RS10355	COG1597	lipid kinase activity
DWB98_RS10365	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
DWB98_RS10370	COG1174	glycine betaine transport
DWB98_RS10380	COG0514	ATP-dependent DNA helicase (RecQ)
DWB98_RS10385	COG0488	(ABC) transporter
DWB98_RS10395	COG1368	sulfuric ester hydrolase activity
DWB98_RS10405	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
DWB98_RS10420	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
DWB98_RS10425	COG0512	Glutamine amidotransferase of anthranilate synthase
DWB98_RS10425	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
DWB98_RS10430	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
DWB98_RS10435	COG0720	synthase
DWB98_RS10440	COG0602	queuosine metabolic process
DWB98_RS10455	COG0463	Glycosyl transferase, family 2
DWB98_RS10460	COG0656	L-ascorbic acid biosynthetic process
DWB98_RS10465	COG1253	flavin adenine dinucleotide binding
DWB98_RS10470	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
DWB98_RS10475	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DWB98_RS10475	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DWB98_RS10475	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DWB98_RS10480	COG1105	Belongs to the carbohydrate kinase PfkB family
DWB98_RS10485	COG1349	DNA-binding transcription factor activity
DWB98_RS10490	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
DWB98_RS10495	COG1210	Utp--glucose-1-phosphate uridylyltransferase
DWB98_RS10525	COG0039	L-malate dehydrogenase activity
DWB98_RS10530	COG0586	Pfam SNARE associated Golgi protein
DWB98_RS10540	COG4989	oxidoreductase activity
DWB98_RS10555	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
DWB98_RS10560	COG4988	ABC transporter
DWB98_RS10565	COG1968	undecaprenyl-diphosphatase activity
DWB98_RS10575	COG1671	Belongs to the UPF0178 family
DWB98_RS10580	COG1611	Belongs to the LOG family
DWB98_RS10585	COG1279	arginine transmembrane transporter activity
DWB98_RS10590	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DWB98_RS10620	COG2814	Major facilitator Superfamily
DWB98_RS10625	COG2839	Protein conserved in bacteria
DWB98_RS10630	COG2814	Major facilitator Superfamily
DWB98_RS10635	COG0583	DNA-binding transcription factor activity
DWB98_RS10645	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
DWB98_RS10655	COG0217	transcriptional regulatory protein
DWB98_RS10675	COG1388	LysM domain
DWB98_RS10675	COG3942	CHAP domain
DWB98_RS10680	COG0306	phosphate transporter
DWB98_RS10685	COG1392	Phosphate transport regulator
DWB98_RS10690	COG2205	protein histidine kinase activity
DWB98_RS10695	COG0745	RESPONSE REGULATOR receiver
DWB98_RS10700	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DWB98_RS10710	COG0657	acetylesterase activity
DWB98_RS10715	COG3949	Membrane
DWB98_RS10725	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
DWB98_RS10730	COG1461	Dihydroxyacetone kinase
DWB98_RS10735	COG2376	Dihydroxyacetone kinase
DWB98_RS10740	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DWB98_RS10745	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DWB98_RS10750	COG1120	ATPase activity
DWB98_RS10755	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DWB98_RS10760	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
DWB98_RS10765	COG1132	(ABC) transporter
DWB98_RS10770	COG1686	Belongs to the peptidase S11 family
DWB98_RS10775	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
DWB98_RS10785	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
DWB98_RS10790	COG1682	transport, permease protein
DWB98_RS10795	COG1134	teichoic acid transport
DWB98_RS10800	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
DWB98_RS10820	COG1108	ABC-type Mn2 Zn2 transport systems permease components
DWB98_RS10825	COG0803	Belongs to the bacterial solute-binding protein 9 family
DWB98_RS10835	COG1320	monovalent cation:proton antiporter activity
DWB98_RS10840	COG2212	antiporter activity
DWB98_RS10845	COG1863	multisubunit Na H antiporter MnhE subunit
DWB98_RS10850	COG0651	ATP synthesis coupled electron transport
DWB98_RS10855	COG1006	Multisubunit Na H antiporter MnhC subunit
DWB98_RS10860	COG2111	Na H antiporter
DWB98_RS10865	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
DWB98_RS10865	COG2111	Na H antiporter
DWB98_RS10905	COG0596	Alpha beta hydrolase
DWB98_RS10925	COG0546	phosphoglycolate phosphatase activity
DWB98_RS10930	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DWB98_RS10935	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
DWB98_RS10945	COG0018	arginyl-trna synthetase
DWB98_RS10960	COG1078	dGTPase activity
DWB98_RS10965	COG0456	acetyltransferase
DWB98_RS10970	COG0655	NAD(P)H dehydrogenase (quinone) activity
DWB98_RS10975	COG0667	Aldo Keto reductase
DWB98_RS10980	COG4844	belongs to the
DWB98_RS10985	COG1082	Xylose isomerase domain protein TIM barrel
DWB98_RS10990	COG0673	inositol 2-dehydrogenase activity
DWB98_RS11000	COG0673	inositol 2-dehydrogenase activity
DWB98_RS11005	COG1737	Transcriptional regulator
DWB98_RS11010	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DWB98_RS11010	COG1263	PTS System
DWB98_RS11025	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
DWB98_RS11030	COG0095	Lipoate-protein ligase
DWB98_RS11035	COG0280	phosphate acetyltransferase
DWB98_RS11040	COG3253	May function as heme-dependent peroxidase
DWB98_RS11060	COG2363	Small membrane protein
DWB98_RS11070	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
DWB98_RS11075	COG0351	phosphomethylpyrimidine kinase
DWB98_RS11100	COG0183	Belongs to the thiolase family
DWB98_RS11105	COG0318	PFAM AMP-dependent synthetase and ligase
DWB98_RS11115	COG3493	citrate carrier protein
DWB98_RS11120	COG0384	phenazine biosynthesis protein PhzF
DWB98_RS11130	COG2329	Antibiotic biosynthesis monooxygenase
DWB98_RS11155	COG2832	Protein of unknown function (DUF454)
DWB98_RS11160	COG4565	transcriptional regulatory protein
DWB98_RS11165	COG3290	protein histidine kinase activity
DWB98_RS11170	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
DWB98_RS11175	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
DWB98_RS11180	COG0363	glucosamine-6-phosphate deaminase activity
DWB98_RS11190	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
DWB98_RS11195	COG1469	GTP cyclohydrolase I activity
DWB98_RS11210	COG0431	NADPH-dependent FMN reductase
DWB98_RS11215	COG0561	phosphatase activity
DWB98_RS11225	COG1428	Deoxynucleoside kinase
DWB98_RS11230	COG1428	Deoxynucleoside kinase
DWB98_RS11240	COG0546	phosphoglycolate phosphatase activity
DWB98_RS11260	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DWB98_RS11275	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
DWB98_RS11280	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DWB98_RS11300	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
DWB98_RS11310	COG2824	Alkylphosphonate utilization operon protein PhnA
DWB98_RS11320	COG1113	amino acid transport
DWB98_RS11325	COG3239	Fatty acid desaturase
DWB98_RS11340	COG2040	homocysteine
DWB98_RS11345	COG0833	amino acid
DWB98_RS11355	COG0010	Belongs to the arginase family
DWB98_RS11360	COG1914	H( )-stimulated, divalent metal cation uptake system
DWB98_RS11375	COG1069	ribulokinase activity
DWB98_RS11380	COG1063	alcohol dehydrogenase
DWB98_RS11385	COG2814	Major facilitator Superfamily
DWB98_RS11390	COG1349	DNA-binding transcription factor activity
DWB98_RS11395	COG1132	(ABC) transporter
DWB98_RS11400	COG1028	Short-chain dehydrogenase reductase Sdr
DWB98_RS11405	COG1312	Catalyzes the dehydration of D-mannonate
DWB98_RS11410	COG1904	glucuronate isomerase
DWB98_RS11430	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DWB98_RS11445	COG0583	DNA-binding transcription factor activity
DWB98_RS11465	COG0667	Aldo Keto reductase
DWB98_RS11485	COG1686	Belongs to the peptidase S11 family
DWB98_RS11500	COG1028	Short-chain dehydrogenase reductase Sdr
DWB98_RS11505	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
DWB98_RS11510	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
DWB98_RS11550	COG1473	amidohydrolase
DWB98_RS11555	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
DWB98_RS11560	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
DWB98_RS11565	COG0049	tRNA binding
DWB98_RS11570	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
DWB98_RS11580	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
DWB98_RS11585	COG0085	RNA polymerase activity
DWB98_RS11590	COG2813	Specifically methylates the guanine in position
DWB98_RS11595	COG0222	ribosome binding
DWB98_RS11600	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
DWB98_RS11610	COG0081	regulation of translation
DWB98_RS11615	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
DWB98_RS11620	COG0250	Participates in transcription elongation, termination and antitermination
DWB98_RS11645	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DWB98_RS11650	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
DWB98_RS11655	COG0215	cysteine-tRNA ligase activity
DWB98_RS11660	COG1045	serine acetyltransferase
DWB98_RS11665	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DWB98_RS11670	COG4956	integral membrane protein (PIN domain superfamily)
DWB98_RS11675	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
DWB98_RS11680	COG0542	response to heat
DWB98_RS11685	COG3869	Catalyzes the specific phosphorylation of arginine residues in
DWB98_RS11690	COG3880	PFAM UvrB UvrC protein
DWB98_RS11695	COG4463	regulation of RNA biosynthetic process
DWB98_RS11700	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
DWB98_RS11705	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
DWB98_RS11710	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
DWB98_RS11715	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DWB98_RS11800	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
DWB98_RS11805	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
DWB98_RS11825	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
DWB98_RS11830	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DWB98_RS11845	COG1098	S1 RNA binding domain
DWB98_RS11855	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
DWB98_RS11860	COG3956	TIGRFAM MazG family protein
DWB98_RS11865	COG2244	polysaccharide biosynthetic process
DWB98_RS11870	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
DWB98_RS11875	COG0193	aminoacyl-tRNA hydrolase activity
DWB98_RS11880	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
DWB98_RS11885	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
DWB98_RS11890	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
DWB98_RS11895	COG2088	sporulation resulting in formation of a cellular spore
DWB98_RS11900	COG0251	oxidation-reduction process
DWB98_RS11905	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
DWB98_RS11910	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
DWB98_RS11915	COG4466	Protein conserved in bacteria
DWB98_RS11920	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
DWB98_RS11925	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
DWB98_RS11930	COG0084	hydrolase, TatD family'
DWB98_RS11935	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DWB98_RS11935	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DWB98_RS11940	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
DWB98_RS11945	COG2827	Endonuclease containing a URI domain
DWB98_RS11950	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
DWB98_RS11955	COG4467	Involved in initiation control of chromosome replication
DWB98_RS11960	COG1774	PSP1 C-terminal conserved region
DWB98_RS11965	COG0470	DNA polymerase III
DWB98_RS11970	COG3870	Protein conserved in bacteria
DWB98_RS11975	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
DWB98_RS11980	COG1982	Orn Lys Arg decarboxylase major
DWB98_RS12015	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
DWB98_RS12020	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
DWB98_RS12025	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
DWB98_RS12030	COG3153	acetyltransferase
DWB98_RS12040	COG2188	Transcriptional regulator
DWB98_RS12045	COG0366	Alpha amylase catalytic
DWB98_RS12050	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DWB98_RS12050	COG1263	PTS System
DWB98_RS12060	COG0493	'glutamate synthase
DWB98_RS12065	COG0067	glutamate synthase
DWB98_RS12065	COG0069	glutamate synthase activity
DWB98_RS12065	COG0070	glutamate synthase
DWB98_RS12085	COG0004	ammonium transporteR
DWB98_RS12090	COG0494	nUDIX hydrolase
DWB98_RS12100	COG3942	CHAP domain
DWB98_RS12100	COG1388	LysM domain
DWB98_RS12110	COG0129	dihydroxy-acid dehydratase activity
DWB98_RS12125	COG0733	neurotransmitter:sodium symporter activity
DWB98_RS12130	COG1114	Component of the transport system for branched-chain amino acids
DWB98_RS12135	COG5646	InterPro IPR014922
DWB98_RS12140	COG2268	Band 7 protein
DWB98_RS12165	COG0789	Transcriptional regulator
DWB98_RS12180	COG4195	phage-related replication protein
DWB98_RS12185	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
DWB98_RS12190	COG2807	transmembrane transport
DWB98_RS12205	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
DWB98_RS12210	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
DWB98_RS12215	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
DWB98_RS12220	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
DWB98_RS12225	COG3257	ureidoglycine aminohydrolase activity
DWB98_RS12230	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DWB98_RS12240	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DWB98_RS12245	COG0406	alpha-ribazole phosphatase activity
DWB98_RS12255	COG1595	DNA-templated transcription, initiation
DWB98_RS12265	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
DWB98_RS12275	COG1876	peptidase activity
DWB98_RS12280	COG0753	catalase activity
DWB98_RS12290	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
DWB98_RS12295	COG1953	Uracil, thiamine, allantoin
DWB98_RS12300	COG2508	Transcriptional regulator
DWB98_RS12305	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
DWB98_RS12305	COG0456	acetyltransferase
DWB98_RS12310	COG2814	Major facilitator Superfamily
DWB98_RS12330	COG1301	dicarboxylic acid transport
DWB98_RS12335	COG0519	Catalyzes the synthesis of GMP from XMP
DWB98_RS12335	COG0518	GMP synthase (glutamine-hydrolyzing) activity
DWB98_RS12340	COG0517	IMP dehydrogenase activity
DWB98_RS12340	COG0516	GMP reductase activity
DWB98_RS12345	COG2233	PERMEase
DWB98_RS12350	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
DWB98_RS12365	COG5183	chlorophyll binding
DWB98_RS12370	COG1823	symporter activity
DWB98_RS12380	COG1760	l-serine dehydratase
DWB98_RS12385	COG1760	l-serine dehydratase
DWB98_RS12400	COG0778	Nitroreductase
DWB98_RS12405	COG0753	catalase activity
DWB98_RS12410	COG0450	alkyl hydroperoxide reductase
DWB98_RS12415	COG3634	alkyl hydroperoxide reductase activity
DWB98_RS12450	COG1280	lysine exporter protein (LysE YggA)
DWB98_RS12455	COG2076	Multidrug Resistance protein
DWB98_RS12460	COG2076	Multidrug Resistance protein
DWB98_RS12480	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DWB98_RS12495	COG4195	phage-related replication protein
DWB98_RS12500	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
DWB98_RS12525	COG0583	DNA-binding transcription factor activity
DWB98_RS12535	COG3266	domain, Protein
DWB98_RS12535	COG4193	domain, Protein
DWB98_RS12535	COG5632	N-Acetylmuramoyl-L-alanine amidase
DWB98_RS12555	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DWB98_RS12560	COG2210	Belongs to the sulfur carrier protein TusA family
DWB98_RS12565	COG1937	Protein conserved in bacteria
DWB98_RS12570	COG0730	response to heat
DWB98_RS12580	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
DWB98_RS12605	COG0360	Binds together with S18 to 16S ribosomal RNA
DWB98_RS12615	COG0012	GTP binding
DWB98_RS12620	COG4481	Protein conserved in bacteria
DWB98_RS12625	COG0668	transmembrane transport
DWB98_RS12630	COG5609	conserved protein (DUF2294)
DWB98_RS12635	COG3002	Belongs to the UPF0753 family
DWB98_RS12640	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
DWB98_RS12645	COG2207	Transcriptional regulator
DWB98_RS12645	COG1917	Cupin 2, conserved barrel domain protein
DWB98_RS12650	COG1486	melibiose metabolic process
DWB98_RS12655	COG2211	Major facilitator Superfamily
DWB98_RS12670	COG2084	Dehydrogenase
DWB98_RS12675	COG1064	alcohol dehydrogenase
DWB98_RS12680	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
DWB98_RS12710	COG1733	regulation of RNA biosynthetic process
DWB98_RS12730	COG1136	(ABC) transporter
DWB98_RS12740	COG1288	antiporter activity
DWB98_RS12750	COG0789	Transcriptional regulator
DWB98_RS12750	COG4978	Transcriptional regulator
DWB98_RS12770	COG1012	belongs to the aldehyde dehydrogenase family
DWB98_RS12780	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DWB98_RS12785	COG2814	Major facilitator Superfamily
DWB98_RS12790	COG1473	amidohydrolase
DWB98_RS12795	COG2814	Major facilitator Superfamily
DWB98_RS12800	COG1733	regulation of RNA biosynthetic process
DWB98_RS12805	COG2030	dehydratase
DWB98_RS12810	COG3759	membrane
DWB98_RS12815	COG2814	Major facilitator Superfamily
DWB98_RS12830	COG0772	Belongs to the SEDS family
DWB98_RS12835	COG2226	methyltransferase
DWB98_RS12850	COG0529	Catalyzes the synthesis of activated sulfate
DWB98_RS12855	COG2046	Belongs to the sulfate adenylyltransferase family
DWB98_RS12860	COG0730	response to heat
DWB98_RS12880	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
DWB98_RS12885	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
DWB98_RS12890	COG0175	sulfate reduction
DWB98_RS12895	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
DWB98_RS12895	COG1017	nitric oxide dioxygenase activity
DWB98_RS12900	COG1475	DNA binding
DWB98_RS12905	COG0626	cystathionine gamma-synthase activity
DWB98_RS12910	COG0626	cystathionine gamma-synthase activity
DWB98_RS12915	COG0646	methionine synthase
DWB98_RS12915	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
DWB98_RS12920	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
DWB98_RS12930	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
DWB98_RS12960	COG0183	Belongs to the thiolase family
DWB98_RS12970	COG1960	acyl-CoA dehydrogenase activity
DWB98_RS12975	COG0318	PFAM AMP-dependent synthetase and ligase
DWB98_RS12985	COG2239	Acts as a magnesium transporter
DWB98_RS13010	COG0561	phosphatase activity
DWB98_RS13015	COG0583	DNA-binding transcription factor activity
DWB98_RS13020	COG1607	acyl-coa hydrolase
DWB98_RS13050	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
DWB98_RS13050	COG0463	Glycosyl transferase, family 2
DWB98_RS13070	COG0531	amino acid
DWB98_RS13075	COG0656	L-ascorbic acid biosynthetic process
DWB98_RS13080	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
DWB98_RS13105	COG0789	Transcriptional regulator
DWB98_RS13120	COG2271	Major facilitator Superfamily
DWB98_RS13125	COG1966	Carbon starvation protein
DWB98_RS13135	COG0357	Ribosomal RNA small subunit methyltransferase G
DWB98_RS13140	COG0445	tRNA wobble uridine modification
DWB98_RS13145	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
DWB98_RS13150	COG0594	ribonuclease P activity
DWB98_RS13445	COG1705	Flagellar rod assembly protein muramidase FlgJ
DWB98_RS13445	COG3942	CHAP domain