locus-tag	class	description
BE24_RS00005	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BE24_RS00010	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
BE24_RS00015	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
BE24_RS00020	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BE24_RS00025	COG4463	regulation of RNA biosynthetic process
BE24_RS00030	COG3880	PFAM UvrB UvrC protein
BE24_RS00035	COG3869	Catalyzes the specific phosphorylation of arginine residues in
BE24_RS00040	COG0542	response to heat
BE24_RS00045	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
BE24_RS00050	COG4956	integral membrane protein (PIN domain superfamily)
BE24_RS00055	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BE24_RS00060	COG1045	serine acetyltransferase
BE24_RS00065	COG0215	cysteine-tRNA ligase activity
BE24_RS00070	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
BE24_RS00075	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BE24_RS00095	COG0250	Participates in transcription elongation, termination and antitermination
BE24_RS00100	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
BE24_RS00105	COG0081	regulation of translation
BE24_RS00110	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
BE24_RS00120	COG2813	Specifically methylates the guanine in position
BE24_RS00125	COG0085	RNA polymerase activity
BE24_RS00130	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
BE24_RS00140	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
BE24_RS00145	COG0049	tRNA binding
BE24_RS00150	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BE24_RS00155	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BE24_RS00160	COG1473	amidohydrolase
BE24_RS00200	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
BE24_RS00205	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
BE24_RS00210	COG1028	Short-chain dehydrogenase reductase Sdr
BE24_RS00225	COG1686	Belongs to the peptidase S11 family
BE24_RS00230	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
BE24_RS00255	COG0667	Aldo Keto reductase
BE24_RS00275	COG1522	sequence-specific DNA binding
BE24_RS00280	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
BE24_RS00300	COG0583	DNA-binding transcription factor activity
BE24_RS00315	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BE24_RS00340	COG1312	Catalyzes the dehydration of D-mannonate
BE24_RS00345	COG1028	Short-chain dehydrogenase reductase Sdr
BE24_RS00350	COG1132	(ABC) transporter
BE24_RS00355	COG1349	DNA-binding transcription factor activity
BE24_RS00360	COG2814	Major facilitator Superfamily
BE24_RS00365	COG1063	alcohol dehydrogenase
BE24_RS00370	COG1069	ribulokinase activity
BE24_RS00385	COG1914	H( )-stimulated, divalent metal cation uptake system
BE24_RS00390	COG0010	Belongs to the arginase family
BE24_RS00400	COG0833	amino acid
BE24_RS00405	COG2040	homocysteine
BE24_RS00415	COG3239	Fatty acid desaturase
BE24_RS00420	COG1113	amino acid transport
BE24_RS00430	COG2824	Alkylphosphonate utilization operon protein PhnA
BE24_RS00440	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
BE24_RS00460	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BE24_RS00465	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
BE24_RS00480	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BE24_RS00500	COG0546	phosphoglycolate phosphatase activity
BE24_RS00510	COG1428	Deoxynucleoside kinase
BE24_RS00515	COG1428	Deoxynucleoside kinase
BE24_RS00525	COG0561	phosphatase activity
BE24_RS00530	COG0431	NADPH-dependent FMN reductase
BE24_RS00545	COG1469	GTP cyclohydrolase I activity
BE24_RS00550	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BE24_RS00560	COG0363	glucosamine-6-phosphate deaminase activity
BE24_RS00565	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
BE24_RS00570	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
BE24_RS00575	COG3290	protein histidine kinase activity
BE24_RS00580	COG4565	transcriptional regulatory protein
BE24_RS00585	COG2832	Protein of unknown function (DUF454)
BE24_RS00600	COG2329	Antibiotic biosynthesis monooxygenase
BE24_RS00605	COG0384	phenazine biosynthesis protein PhzF
BE24_RS00610	COG3493	citrate carrier protein
BE24_RS00620	COG0318	PFAM AMP-dependent synthetase and ligase
BE24_RS00625	COG0183	Belongs to the thiolase family
BE24_RS00655	COG0351	phosphomethylpyrimidine kinase
BE24_RS00660	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
BE24_RS00670	COG2363	Small membrane protein
BE24_RS00690	COG3253	May function as heme-dependent peroxidase
BE24_RS00695	COG0280	phosphate acetyltransferase
BE24_RS00700	COG0095	Lipoate-protein ligase
BE24_RS00720	COG4844	belongs to the
BE24_RS00725	COG0667	Aldo Keto reductase
BE24_RS00730	COG0655	NAD(P)H dehydrogenase (quinone) activity
BE24_RS00735	COG0456	acetyltransferase
BE24_RS00740	COG1078	dGTPase activity
BE24_RS00755	COG0018	arginyl-trna synthetase
BE24_RS00765	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BE24_RS00770	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BE24_RS00775	COG0546	phosphoglycolate phosphatase activity
BE24_RS00795	COG0596	Alpha beta hydrolase
BE24_RS00835	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BE24_RS00835	COG2111	Na H antiporter
BE24_RS00840	COG2111	Na H antiporter
BE24_RS00845	COG1006	Multisubunit Na H antiporter MnhC subunit
BE24_RS00850	COG0651	ATP synthesis coupled electron transport
BE24_RS00855	COG1863	multisubunit Na H antiporter MnhE subunit
BE24_RS00860	COG2212	antiporter activity
BE24_RS00865	COG1320	monovalent cation:proton antiporter activity
BE24_RS00875	COG0803	Belongs to the bacterial solute-binding protein 9 family
BE24_RS00880	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BE24_RS00900	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
BE24_RS00905	COG1134	teichoic acid transport
BE24_RS00910	COG1682	transport, permease protein
BE24_RS00915	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
BE24_RS00925	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
BE24_RS00935	COG1132	(ABC) transporter
BE24_RS00940	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BE24_RS00945	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BE24_RS00950	COG1120	ATPase activity
BE24_RS00955	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BE24_RS00960	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BE24_RS00965	COG2376	Dihydroxyacetone kinase
BE24_RS00970	COG1461	Dihydroxyacetone kinase
BE24_RS00975	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
BE24_RS00985	COG3949	Membrane
BE24_RS00990	COG0657	acetylesterase activity
BE24_RS01000	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BE24_RS01005	COG0745	RESPONSE REGULATOR receiver
BE24_RS01010	COG2205	protein histidine kinase activity
BE24_RS01015	COG1392	Phosphate transport regulator
BE24_RS01020	COG0306	phosphate transporter
BE24_RS01025	COG3942	CHAP domain
BE24_RS01025	COG1388	LysM domain
BE24_RS01045	COG0217	transcriptional regulatory protein
BE24_RS01055	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
BE24_RS01065	COG0583	DNA-binding transcription factor activity
BE24_RS01070	COG2814	Major facilitator Superfamily
BE24_RS01075	COG2839	Protein conserved in bacteria
BE24_RS01080	COG2814	Major facilitator Superfamily
BE24_RS01110	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BE24_RS01115	COG1279	arginine transmembrane transporter activity
BE24_RS01120	COG1611	Belongs to the LOG family
BE24_RS01125	COG1671	Belongs to the UPF0178 family
BE24_RS01135	COG1968	undecaprenyl-diphosphatase activity
BE24_RS01140	COG4988	ABC transporter
BE24_RS01145	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
BE24_RS01160	COG4989	oxidoreductase activity
BE24_RS01170	COG0586	Pfam SNARE associated Golgi protein
BE24_RS01175	COG0039	L-malate dehydrogenase activity
BE24_RS01205	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BE24_RS01210	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BE24_RS01215	COG1349	DNA-binding transcription factor activity
BE24_RS01220	COG1105	Belongs to the carbohydrate kinase PfkB family
BE24_RS01225	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BE24_RS01225	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BE24_RS01225	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BE24_RS01230	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BE24_RS01235	COG1253	flavin adenine dinucleotide binding
BE24_RS01240	COG0656	L-ascorbic acid biosynthetic process
BE24_RS01245	COG0463	Glycosyl transferase, family 2
BE24_RS01260	COG0602	queuosine metabolic process
BE24_RS01265	COG0720	synthase
BE24_RS01270	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
BE24_RS01275	COG0512	Glutamine amidotransferase of anthranilate synthase
BE24_RS01275	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BE24_RS01280	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BE24_RS01290	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
BE24_RS01300	COG1368	sulfuric ester hydrolase activity
BE24_RS01310	COG0488	(ABC) transporter
BE24_RS01315	COG0514	ATP-dependent DNA helicase (RecQ)
BE24_RS01325	COG1174	glycine betaine transport
BE24_RS01330	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BE24_RS01340	COG1597	lipid kinase activity
BE24_RS01345	COG3104	oligopeptide transport
BE24_RS01350	COG3104	oligopeptide transport
BE24_RS01355	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
BE24_RS01365	COG1780	Probably involved in ribonucleotide reductase function
BE24_RS01370	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BE24_RS01375	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BE24_RS01380	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BE24_RS01385	COG4605	iron ion homeostasis
BE24_RS01390	COG4604	ABC transporter, ATP-binding protein
BE24_RS01395	COG4607	ABC-type enterochelin transport system periplasmic component
BE24_RS01410	COG0812	UDP-N-acetylmuramate dehydrogenase activity
BE24_RS01430	COG1929	Belongs to the glycerate kinase type-1 family
BE24_RS01435	COG2195	Cleaves the N-terminal amino acid of tripeptides
BE24_RS01450	COG2199	diguanylate cyclase activity
BE24_RS01455	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BE24_RS01460	COG1739	Uncharacterized protein family UPF0029
BE24_RS01470	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
BE24_RS01475	COG1040	competence protein
BE24_RS01480	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
BE24_RS01485	COG0653	protein targeting
BE24_RS01490	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
BE24_RS01495	COG1388	LysM domain
BE24_RS01495	COG3942	CHAP domain
BE24_RS01510	COG0556	nucleotide-excision repair
BE24_RS01520	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
BE24_RS01525	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
BE24_RS01530	COG0110	maltose O-acetyltransferase activity
BE24_RS01540	COG0492	ferredoxin-NADP+ reductase activity
BE24_RS01545	COG1660	Displays ATPase and GTPase activities
BE24_RS01550	COG0391	Required for morphogenesis under gluconeogenic growth conditions
BE24_RS01555	COG1481	regulation of sporulation
BE24_RS01565	COG0740	serine-type endopeptidase activity
BE24_RS01575	COG1090	epimerase
BE24_RS01605	COG0126	phosphoglycerate kinase activity
BE24_RS01610	COG0149	triose-phosphate isomerase activity
BE24_RS01615	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
BE24_RS01620	COG0148	phosphopyruvate hydratase activity
BE24_RS01630	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BE24_RS01635	COG1647	Serine aminopeptidase, S33
BE24_RS01640	COG0557	exoribonuclease II activity
BE24_RS01645	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
BE24_RS01665	COG0346	lactoylglutathione lyase activity
BE24_RS01685	COG0640	Transcriptional regulator
BE24_RS01710	COG1073	alpha beta
BE24_RS01725	COG0346	lactoylglutathione lyase activity
BE24_RS01730	COG2153	protein acetylation
BE24_RS01760	COG2314	TM2 domain
BE24_RS01775	COG2851	Citrate transporter
BE24_RS01790	COG1764	response to oxidative stress
BE24_RS01795	COG0710	3-dehydroquinate dehydratase activity
BE24_RS01800	COG0778	Nitroreductase
BE24_RS01805	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BE24_RS01810	COG1393	Belongs to the ArsC family
BE24_RS01815	COG0509	glycine decarboxylation via glycine cleavage system
BE24_RS01820	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
BE24_RS01825	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BE24_RS01830	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BE24_RS01835	COG2011	ABC-type metal ion transport system permease component
BE24_RS01840	COG1464	Belongs to the NlpA lipoprotein family
BE24_RS01850	COG1253	flavin adenine dinucleotide binding
BE24_RS01860	COG0396	ATPase activity
BE24_RS01865	COG0719	Fe-S assembly protein
BE24_RS01870	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BE24_RS01875	COG0822	iron-sulfur transferase activity
BE24_RS01880	COG0719	Fe-S assembly protein
BE24_RS01885	COG3223	Belongs to the PsiE family
BE24_RS01890	COG0454	-acetyltransferase
BE24_RS01900	COG1253	flavin adenine dinucleotide binding
BE24_RS01905	COG2070	2-Nitropropane dioxygenase
BE24_RS01910	COG1801	Protein of unknown function DUF72
BE24_RS01915	COG0730	response to heat
BE24_RS01920	COG0737	Belongs to the 5'-nucleotidase family
BE24_RS01925	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
BE24_RS01930	COG4470	Protein conserved in bacteria
BE24_RS01940	COG2445	Protein of unknown function DUF86
BE24_RS01945	COG0647	UMP catabolic process
BE24_RS01950	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BE24_RS01960	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BE24_RS01965	COG1696	Membrane protein involved in D-alanine export
BE24_RS01970	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BE24_RS01975	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
BE24_RS01980	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
BE24_RS01985	COG4837	Protein of unknown function (DUF1462)
BE24_RS01990	COG1252	NADH dehydrogenase
BE24_RS01995	COG4844	belongs to the
BE24_RS02000	COG0316	Belongs to the HesB IscA family
BE24_RS02005	COG1252	NADH dehydrogenase
BE24_RS02010	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
BE24_RS02015	COG2056	Na+-H+ antiporter family
BE24_RS02020	COG2050	protein possibly involved in aromatic compounds catabolism
BE24_RS02035	COG1320	monovalent cation:proton antiporter activity
BE24_RS02040	COG2212	antiporter activity
BE24_RS02045	COG1863	multisubunit Na H antiporter MnhE subunit
BE24_RS02050	COG0651	ATP synthesis coupled electron transport
BE24_RS02055	COG1006	Multisubunit Na H antiporter MnhC subunit
BE24_RS02060	COG2111	Na H antiporter
BE24_RS02065	COG2111	Na H antiporter
BE24_RS02065	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BE24_RS02075	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BE24_RS02080	COG1098	S1 RNA binding domain
BE24_RS02085	COG1902	pentaerythritol trinitrate reductase activity
BE24_RS02090	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BE24_RS02100	COG0584	glycerophosphoryl diester phosphodiesterase
BE24_RS02105	COG0165	Argininosuccinate lyase
BE24_RS02110	COG0137	argininosuccinate synthase activity
BE24_RS02115	COG0166	Belongs to the GPI family
BE24_RS02120	COG0398	Pfam SNARE associated Golgi protein
BE24_RS02135	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
BE24_RS02145	COG2311	Membrane
BE24_RS02150	COG0179	Fumarylacetoacetate (FAA) hydrolase
BE24_RS02160	COG0446	pyridine nucleotide-disulphide oxidoreductase
BE24_RS02165	COG0561	phosphatase activity
BE24_RS02180	COG0542	response to heat
BE24_RS02190	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BE24_RS02205	COG0601	transmembrane transport
BE24_RS02210	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BE24_RS02215	COG0444	Belongs to the ABC transporter superfamily
BE24_RS02220	COG4608	Belongs to the ABC transporter superfamily
BE24_RS02230	COG0180	Tryptophanyl-tRNA synthetase
BE24_RS02235	COG1393	Belongs to the ArsC family
BE24_RS02240	COG4862	establishment of competence for transformation
BE24_RS02250	COG1164	Oligoendopeptidase f
BE24_RS02255	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
BE24_RS02260	COG2346	COG2346, Truncated hemoglobins
BE24_RS02275	COG2357	RelA SpoT domain protein
BE24_RS02280	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BE24_RS02285	COG0564	pseudouridine synthase activity
BE24_RS02290	COG2239	Acts as a magnesium transporter
BE24_RS02295	COG0569	domain protein
BE24_RS02295	COG0475	glutathione-regulated potassium exporter activity
BE24_RS02305	COG0628	permease
BE24_RS02310	COG1115	amino acid carrier protein
BE24_RS02315	COG2382	esterase
BE24_RS02320	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
BE24_RS02325	COG2814	Major facilitator Superfamily
BE24_RS02330	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BE24_RS02335	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BE24_RS02345	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
BE24_RS02350	COG0861	Integral membrane protein TerC family
BE24_RS02355	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BE24_RS02360	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BE24_RS02365	COG0737	Belongs to the 5'-nucleotidase family
BE24_RS02375	COG4873	Protein conserved in bacteria
BE24_RS02390	COG4903	ComK protein
BE24_RS02410	COG2314	TM2 domain
BE24_RS02420	COG1575	Belongs to the MenA family. Type 1 subfamily
BE24_RS02425	COG1169	isochorismate synthase
BE24_RS02430	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
BE24_RS02435	COG2267	carboxylic ester hydrolase activity
BE24_RS02440	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
BE24_RS02445	COG1846	Transcriptional regulator
BE24_RS02450	COG0436	Aminotransferase
BE24_RS02455	COG3594	Acyltransferase
BE24_RS02480	COG1316	TRANSCRIPTIONal
BE24_RS02485	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BE24_RS02500	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
BE24_RS02505	COG1845	cytochrome c oxidase, subunit III
BE24_RS02510	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BE24_RS02515	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BE24_RS02525	COG1017	nitric oxide dioxygenase activity
BE24_RS02525	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BE24_RS02530	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
BE24_RS02535	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
BE24_RS02540	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
BE24_RS02545	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
BE24_RS02550	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BE24_RS02555	COG0047	phosphoribosylformylglycinamidine synthase activity
BE24_RS02560	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BE24_RS02570	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
BE24_RS02580	COG0138	bifunctional purine biosynthesis protein purh
BE24_RS02585	COG0151	Belongs to the GarS family
BE24_RS02595	COG4172	Belongs to the ABC transporter superfamily
BE24_RS02610	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
BE24_RS02620	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BE24_RS02625	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BE24_RS02635	COG1271	oxidase subunit
BE24_RS02640	COG1294	oxidase, subunit
BE24_RS02645	COG0569	domain protein
BE24_RS02650	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BE24_RS02655	COG5503	Protein of unknown function (DUF1447)
BE24_RS02665	COG0242	peptide deformylase activity
BE24_RS02695	COG4476	Belongs to the UPF0223 family
BE24_RS02705	COG3842	ATPase activity
BE24_RS02710	COG1176	ABC-type spermidine putrescine transport system, permease component I
BE24_RS02715	COG1177	transmembrane transport
BE24_RS02730	COG1914	H( )-stimulated, divalent metal cation uptake system
BE24_RS02740	COG4493	Belongs to the UPF0637 family
BE24_RS02745	COG0483	inositol monophosphate 1-phosphatase activity
BE24_RS02755	COG1217	gtp-binding protein TYPA
BE24_RS02760	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BE24_RS02765	COG4838	Belongs to the UPF0358 family
BE24_RS02770	COG0772	Belongs to the SEDS family
BE24_RS02780	COG1612	heme a metabolic process
BE24_RS02785	COG0109	protoheme IX farnesyltransferase activity
BE24_RS02795	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BE24_RS02805	COG3679	Belongs to the UPF0342 family
BE24_RS02810	COG0584	glycerophosphoryl diester phosphodiesterase
BE24_RS02815	COG4471	UPF0298 protein
BE24_RS02825	COG0742	ribosomal rna small subunit methyltransferase
BE24_RS02830	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
BE24_RS02835	COG1323	Belongs to the UPF0348 family
BE24_RS02845	COG0333	Belongs to the bacterial ribosomal protein bL32 family
BE24_RS02855	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BE24_RS02860	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
BE24_RS02865	COG0072	phenylalanine-tRNA ligase activity
BE24_RS02870	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BE24_RS02875	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
BE24_RS02885	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
BE24_RS02885	COG1796	DNA polymerase
BE24_RS02890	COG1193	negative regulation of DNA recombination
BE24_RS02895	COG3118	belongs to the thioredoxin family
BE24_RS02900	COG0322	excinuclease ABC activity
BE24_RS02905	COG2009	succinate dehydrogenase
BE24_RS02910	COG1053	succinate dehydrogenase
BE24_RS02915	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BE24_RS02920	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
BE24_RS02925	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
BE24_RS02980	COG1011	Hydrolase
BE24_RS02985	COG0454	-acetyltransferase
BE24_RS02990	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
BE24_RS02995	COG2001	Belongs to the MraZ family
BE24_RS03000	COG0275	rRNA processing
BE24_RS03005	COG4839	cell division protein FtsL
BE24_RS03010	COG0768	penicillin binding
BE24_RS03015	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BE24_RS03020	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
BE24_RS03030	COG0849	cell division
BE24_RS03035	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BE24_RS03040	COG1496	oxidoreductase activity
BE24_RS03045	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
BE24_RS03050	COG1799	cell septum assembly
BE24_RS03055	COG0762	integral membrane protein
BE24_RS03065	COG3599	regulation of cell shape
BE24_RS03070	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
BE24_RS03080	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
BE24_RS03085	COG0564	pseudouridine synthase activity
BE24_RS03090	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
BE24_RS03100	COG0540	Belongs to the ATCase OTCase family
BE24_RS03110	COG0505	Belongs to the CarA family
BE24_RS03115	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
BE24_RS03120	COG0284	orotidine-5'-phosphate decarboxylase activity
BE24_RS03125	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
BE24_RS03135	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BE24_RS03145	COG1293	RNA-binding protein homologous to eukaryotic snRNP
BE24_RS03155	COG1758	RNA polymerase activity
BE24_RS03160	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BE24_RS03165	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BE24_RS03180	COG0242	peptide deformylase activity
BE24_RS03185	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BE24_RS03190	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BE24_RS03190	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BE24_RS03195	COG0820	rRNA (adenine-C2-)-methyltransferase activity
BE24_RS03210	COG1162	GTPase activity
BE24_RS03215	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BE24_RS03220	COG1564	THIamine pyrophosphokinase
BE24_RS03225	COG0227	Belongs to the bacterial ribosomal protein bL28 family
BE24_RS03230	COG1302	Protein conserved in bacteria
BE24_RS03235	COG1461	Dihydroxyacetone kinase
BE24_RS03240	COG1760	l-serine dehydratase
BE24_RS03245	COG1760	l-serine dehydratase
BE24_RS03250	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BE24_RS03260	COG1349	DNA-binding transcription factor activity
BE24_RS03265	COG0416	fatty acid biosynthetic process
BE24_RS03280	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BE24_RS03285	COG0571	ribonuclease III activity
BE24_RS03290	COG1196	nuclear chromosome segregation
BE24_RS03295	COG0552	protein localization to endoplasmic reticulum
BE24_RS03300	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
BE24_RS03305	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BE24_RS03310	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BE24_RS03315	COG1028	Short-chain dehydrogenase reductase Sdr
BE24_RS03320	COG0228	four-way junction DNA binding
BE24_RS03325	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
BE24_RS03330	COG0336	Belongs to the RNA methyltransferase TrmD family
BE24_RS03335	COG0335	large ribosomal subunit rRNA binding
BE24_RS03345	COG4485	Bacterial membrane protein, YfhO
BE24_RS03355	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BE24_RS03360	COG0045	succinate-CoA ligase (ADP-forming) activity
BE24_RS03370	COG0758	DNA mediated transformation
BE24_RS03375	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BE24_RS03380	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
BE24_RS03385	COG4974	Belongs to the 'phage' integrase family
BE24_RS03390	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
BE24_RS03395	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
BE24_RS03400	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
BE24_RS03405	COG0052	Belongs to the universal ribosomal protein uS2 family
BE24_RS03410	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
BE24_RS03415	COG0528	UMP kinase activity
BE24_RS03420	COG0233	cytoplasmic translational termination
BE24_RS03425	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
BE24_RS03430	COG4589	Belongs to the CDS family
BE24_RS03440	COG0442	prolyl-tRNA aminoacylation
BE24_RS03445	COG2176	DNA-directed DNA polymerase activity
BE24_RS03450	COG0779	Required for maturation of 30S ribosomal subunits
BE24_RS03455	COG0195	Participates in both transcription termination and antitermination
BE24_RS03460	COG2740	Nucleic-acid-binding protein implicated in transcription termination
BE24_RS03465	COG1358	cellular component organization or biogenesis
BE24_RS03470	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
BE24_RS03485	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
BE24_RS03490	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
BE24_RS03495	COG0196	riboflavin kinase activity
BE24_RS03500	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
BE24_RS03505	COG1185	polyribonucleotide nucleotidyltransferase activity
BE24_RS03510	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BE24_RS03515	COG1674	ftsk spoiiie
BE24_RS03520	COG2188	Transcriptional regulator
BE24_RS03525	COG0612	Peptidase, M16
BE24_RS03530	COG0612	Peptidase, M16
BE24_RS03535	COG0300	oxidoreductase activity
BE24_RS03555	COG1546	Belongs to the CinA family
BE24_RS03555	COG1058	Belongs to the CinA family
BE24_RS03560	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
BE24_RS03565	COG1418	mRNA catabolic process
BE24_RS03575	COG1692	metallophosphoesterase
BE24_RS03580	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
BE24_RS03580	COG0674	pyruvate-flavodoxin oxidoreductase activity
BE24_RS03585	COG1013	pyruvate-flavodoxin oxidoreductase activity
BE24_RS03595	COG4195	phage-related replication protein
BE24_RS03600	COG1959	2 iron, 2 sulfur cluster binding
BE24_RS03615	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BE24_RS03620	COG4550	Control of competence regulator ComK, YlbF/YmcA
BE24_RS03630	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
BE24_RS03635	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
BE24_RS03645	COG1619	proteins homologs of microcin C7 resistance protein MccF
BE24_RS03650	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BE24_RS03655	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
BE24_RS03660	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
BE24_RS03670	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
BE24_RS03675	COG1923	regulation of RNA biosynthetic process
BE24_RS03680	COG0386	Belongs to the glutathione peroxidase family
BE24_RS03685	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BE24_RS03690	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
BE24_RS03695	COG0789	Transcriptional regulator
BE24_RS03705	COG1764	response to oxidative stress
BE24_RS03710	COG2808	Putative FMN-binding domain
BE24_RS03720	COG1131	(ABC) transporter
BE24_RS03725	COG0842	Transport permease protein
BE24_RS03730	COG4585	Histidine kinase
BE24_RS03735	COG2197	response regulator
BE24_RS03750	COG2801	Transposase and inactivated derivatives
BE24_RS03775	COG0527	aspartate kinase activity
BE24_RS03780	COG0460	homoserine dehydrogenase
BE24_RS03785	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
BE24_RS03790	COG0083	homoserine kinase activity
BE24_RS03795	COG0561	phosphatase activity
BE24_RS03805	COG0833	amino acid
BE24_RS03810	COG0753	catalase activity
BE24_RS03815	COG0267	Belongs to the bacterial ribosomal protein bL33 family
BE24_RS03820	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
BE24_RS03825	COG0516	GMP reductase activity
BE24_RS03835	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
BE24_RS03855	COG3763	UPF0154 protein
BE24_RS03865	COG4846	Membrane protein involved in cytochrome C biogenesis
BE24_RS03870	COG0420	3'-5' exonuclease activity
BE24_RS03875	COG0419	ATPase involved in DNA repair
BE24_RS03880	COG1970	mechanosensitive ion channel activity
BE24_RS03885	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BE24_RS03890	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
BE24_RS03895	COG0824	Thioesterase
BE24_RS03900	COG4841	protein insertion into membrane
BE24_RS03905	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
BE24_RS03915	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BE24_RS03920	COG1115	amino acid carrier protein
BE24_RS03925	COG3711	transcriptional antiterminator
BE24_RS03935	COG0628	permease
BE24_RS03940	COG0392	lysyltransferase activity
BE24_RS03940	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
BE24_RS03950	COG1609	Transcriptional regulator
BE24_RS03955	COG1869	D-ribose catabolic process
BE24_RS03960	COG1129	ABC transporter
BE24_RS03965	COG1172	Belongs to the binding-protein-dependent transport system permease family
BE24_RS03970	COG1879	ABC-type sugar transport system periplasmic component
BE24_RS03985	COG1942	4-Oxalocrotonate Tautomerase
BE24_RS03990	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BE24_RS03995	COG0287	Prephenate dehydrogenase
BE24_RS04005	COG1363	Peptidase, m42
BE24_RS04015	COG0584	glycerophosphoryl diester phosphodiesterase
BE24_RS04020	COG0438	transferase activity, transferring glycosyl groups
BE24_RS04035	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BE24_RS04040	COG0512	Glutamine amidotransferase of anthranilate synthase
BE24_RS04045	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BE24_RS04050	COG0134	indole-3-glycerol-phosphate synthase activity
BE24_RS04060	COG0133	tryptophan synthase activity
BE24_RS04075	COG2348	transferase activity, transferring amino-acyl groups
BE24_RS04090	COG4607	ABC-type enterochelin transport system periplasmic component
BE24_RS04100	COG1164	Oligoendopeptidase f
BE24_RS04105	COG0704	Plays a role in the regulation of phosphate uptake
BE24_RS04110	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BE24_RS04115	COG0581	inorganic phosphate transmembrane transporter activity
BE24_RS04120	COG0573	inorganic phosphate transmembrane transporter activity
BE24_RS04125	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BE24_RS04130	COG2996	Protein conserved in bacteria
BE24_RS04135	COG0488	(ABC) transporter
BE24_RS04145	COG0527	aspartate kinase activity
BE24_RS04150	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BE24_RS04155	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BE24_RS04160	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
BE24_RS04170	COG1473	amidohydrolase
BE24_RS04185	COG1278	Cold shock
BE24_RS04195	COG1254	Belongs to the acylphosphatase family
BE24_RS04205	COG3853	Toxic anion resistance protein (TelA)
BE24_RS04210	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BE24_RS04215	COG1114	Component of the transport system for branched-chain amino acids
BE24_RS04220	COG4548	von Willebrand factor, type A
BE24_RS04225	COG0714	Associated with various cellular activities
BE24_RS04250	COG1121	(ABC) transporter
BE24_RS04255	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BE24_RS04280	COG2207	Transcriptional regulator
BE24_RS04280	COG1917	Cupin 2, conserved barrel domain protein
BE24_RS04290	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BE24_RS04300	COG0508	dehydrogenase complex catalyzes the overall conversion of
BE24_RS04305	COG0567	Dehydrogenase, E1 component
BE24_RS04310	COG5002	protein histidine kinase activity
BE24_RS04315	COG0745	RESPONSE REGULATOR receiver
BE24_RS04320	COG0671	phosphoesterase, PA-phosphatase related
BE24_RS04325	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BE24_RS04335	COG0793	Belongs to the peptidase S41A family
BE24_RS04340	COG4479	Belongs to the UPF0346 family
BE24_RS04350	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BE24_RS04370	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
BE24_RS04380	COG1413	lyase activity
BE24_RS04385	COG1413	lyase activity
BE24_RS04395	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
BE24_RS04400	COG3545	Serine hydrolase
BE24_RS04410	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BE24_RS04425	COG2962	Rard protein
BE24_RS04430	COG0116	Belongs to the methyltransferase superfamily
BE24_RS04440	COG4474	Belongs to the UPF0398 family
BE24_RS04450	COG3331	DNA recombination
BE24_RS04455	COG4499	WXG100 protein secretion system (Wss), protein YukC
BE24_RS04455	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BE24_RS04465	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BE24_RS04470	COG3935	DnaD domain protein
BE24_RS04475	COG0017	Asparaginyl-tRNA synthetase
BE24_RS04480	COG1199	ATP-dependent helicase activity
BE24_RS04480	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BE24_RS04490	COG0617	tRNA 3'-terminal CCA addition
BE24_RS04495	COG0438	transferase activity, transferring glycosyl groups
BE24_RS04500	COG1694	Mazg nucleotide pyrophosphohydrolase
BE24_RS04510	COG4347	Protein of unknown function (DUF1405)
BE24_RS04515	COG5582	Belongs to the UPF0302 family
BE24_RS04525	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
BE24_RS04530	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
BE24_RS04535	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
BE24_RS04540	COG0105	UTP biosynthetic process
BE24_RS04545	COG0142	geranyltranstransferase activity
BE24_RS04550	COG2226	methyltransferase
BE24_RS04565	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
BE24_RS04570	COG1160	GTP binding
BE24_RS04575	COG0539	negative regulation of cytoplasmic translation
BE24_RS04580	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
BE24_RS04590	COG0492	ferredoxin-NADP+ reductase activity
BE24_RS04595	COG1388	LysM domain
BE24_RS04600	COG0514	ATP-dependent DNA helicase (RecQ)
BE24_RS04610	COG1141	Ferredoxin
BE24_RS04625	COG0745	RESPONSE REGULATOR receiver
BE24_RS04630	COG1187	pseudouridine synthase activity
BE24_RS04635	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
BE24_RS04640	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
BE24_RS04650	COG4974	Belongs to the 'phage' integrase family
BE24_RS04655	COG0735	belongs to the Fur family
BE24_RS04660	COG0494	nUDIX hydrolase
BE24_RS04665	COG0667	Aldo Keto reductase
BE24_RS04675	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BE24_RS04680	COG1234	tRNA 3'-trailer cleavage
BE24_RS04685	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BE24_RS04695	COG0366	Alpha amylase catalytic
BE24_RS04700	COG1609	Transcriptional regulator
BE24_RS04710	COG2195	Cleaves the N-terminal amino acid of tripeptides
BE24_RS04715	COG4129	membrane
BE24_RS04725	COG0508	dehydrogenase complex catalyzes the overall conversion of
BE24_RS04730	COG0022	dehydrogenase e1 component
BE24_RS04735	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BE24_RS04740	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BE24_RS04745	COG3426	butyrate kinase activity
BE24_RS04750	COG0280	phosphate acetyltransferase
BE24_RS04755	COG0497	DNA recombination
BE24_RS04760	COG1438	arginine binding
BE24_RS04770	COG1722	exodeoxyribonuclease VII activity
BE24_RS04775	COG1570	exodeoxyribonuclease VII activity
BE24_RS04780	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BE24_RS04785	COG1302	Protein conserved in bacteria
BE24_RS04790	COG0439	Biotin carboxylase
BE24_RS04800	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
BE24_RS04805	COG0006	proline dipeptidase activity
BE24_RS04820	COG0095	Lipoate-protein ligase
BE24_RS04825	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BE24_RS04830	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BE24_RS04835	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BE24_RS04840	COG0404	The glycine cleavage system catalyzes the degradation of glycine
BE24_RS04845	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
BE24_RS04880	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BE24_RS04885	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BE24_RS04890	COG0011	TIGRFAM Protein of
BE24_RS04895	COG1940	carbohydrate kinase activity
BE24_RS04900	COG4483	Protein conserved in bacteria
BE24_RS04905	COG0705	Rhomboid family
BE24_RS04905	COG0457	Tetratricopeptide repeat
BE24_RS04910	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BE24_RS04915	COG0267	Belongs to the bacterial ribosomal protein bL33 family
BE24_RS04920	COG0768	penicillin binding
BE24_RS04925	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BE24_RS04935	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BE24_RS04940	COG1121	(ABC) transporter
BE24_RS04945	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
BE24_RS04950	COG0513	Belongs to the DEAD box helicase family
BE24_RS04960	COG2384	SAM-dependent methyltransferase
BE24_RS04965	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BE24_RS04975	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
BE24_RS04980	COG0517	IMP dehydrogenase activity
BE24_RS04985	COG0423	glycine-tRNA ligase activity
BE24_RS04990	COG1381	Involved in DNA repair and RecF pathway recombination
BE24_RS04995	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
BE24_RS05000	COG0295	cytidine deaminase activity
BE24_RS05005	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
BE24_RS05010	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
BE24_RS05015	COG1702	phosphate starvation-inducible protein PhoH
BE24_RS05025	COG4864	UPF0365 protein
BE24_RS05030	COG1030	water channel activity
BE24_RS05035	COG0828	Belongs to the bacterial ribosomal protein bS21 family
BE24_RS05050	COG5632	N-Acetylmuramoyl-L-alanine amidase
BE24_RS05050	COG1388	LysM domain
BE24_RS05235	COG1484	DNA-dependent DNA replication
BE24_RS05295	COG3617	BRO family, N-terminal domain
BE24_RS05315	COG4974	Belongs to the 'phage' integrase family
BE24_RS05320	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BE24_RS05325	COG2264	protein methyltransferase activity
BE24_RS05330	COG0484	heat shock protein binding
BE24_RS05335	COG0443	Heat shock 70 kDa protein
BE24_RS05340	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
BE24_RS05345	COG1420	regulation of RNA biosynthetic process
BE24_RS05350	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BE24_RS05355	COG0481	GTPase activity
BE24_RS05360	COG0268	Binds directly to 16S ribosomal RNA
BE24_RS05375	COG1466	dna polymerase III delta subunit
BE24_RS05385	COG2131	deaminase
BE24_RS05390	COG1596	polysaccharide export
BE24_RS05390	COG1555	photosystem II stabilization
BE24_RS05395	COG2226	methyltransferase
BE24_RS05400	COG0799	negative regulation of ribosome biogenesis
BE24_RS05405	COG1713	HD superfamily hydrolase involved in NAD metabolism
BE24_RS05410	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
BE24_RS05415	COG1534	Rna-binding protein
BE24_RS05420	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BE24_RS05425	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
BE24_RS05430	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
BE24_RS05435	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BE24_RS05440	COG0730	response to heat
BE24_RS05445	COG1914	H( )-stimulated, divalent metal cation uptake system
BE24_RS05450	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
BE24_RS05455	COG0439	Biotin carboxylase
BE24_RS05460	COG0511	ligase activity, forming carbon-carbon bonds
BE24_RS05465	COG1984	allophanate hydrolase subunit 2
BE24_RS05470	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
BE24_RS05475	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BE24_RS05480	COG0572	uridine kinase
BE24_RS05485	COG0826	peptidase U32
BE24_RS05490	COG0826	peptidase U32
BE24_RS05495	COG4122	O-methyltransferase activity
BE24_RS05500	COG3906	Belongs to the UPF0473 family
BE24_RS05505	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
BE24_RS05510	COG4472	Bacterial protein of unknown function (DUF965)
BE24_RS05520	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BE24_RS05530	COG0482	sulfurtransferase activity
BE24_RS05535	COG1104	cysteine desulfurase activity
BE24_RS05540	COG0488	(ABC) transporter
BE24_RS05545	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BE24_RS05555	COG1959	2 iron, 2 sulfur cluster binding
BE24_RS05560	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BE24_RS05565	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
BE24_RS05570	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
BE24_RS05575	COG0124	histidyl-tRNA synthetase
BE24_RS05580	COG0860	N-Acetylmuramoyl-L-alanine amidase
BE24_RS05585	COG1490	D-aminoacyl-tRNA deacylase activity
BE24_RS05590	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BE24_RS05600	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
BE24_RS05600	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BE24_RS05605	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BE24_RS05605	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BE24_RS05610	COG1862	Preprotein translocase
BE24_RS05615	COG0343	queuine tRNA-ribosyltransferase activity
BE24_RS05620	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
BE24_RS05625	COG2255	four-way junction helicase activity
BE24_RS05630	COG0632	four-way junction helicase activity
BE24_RS05635	COG4492	Belongs to the UPF0735 family
BE24_RS05640	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
BE24_RS05645	COG0211	Belongs to the bacterial ribosomal protein bL27 family
BE24_RS05650	COG2868	ribosomal protein
BE24_RS05655	COG0261	This protein binds to 23S rRNA in the presence of protein L20
BE24_RS05680	COG2003	Belongs to the UPF0758 family
BE24_RS05695	COG0285	dihydrofolate synthase activity
BE24_RS05700	COG0525	valine-tRNA ligase activity
BE24_RS05705	COG2818	Glycosylase
BE24_RS05715	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
BE24_RS05720	COG0113	porphobilinogen synthase activity
BE24_RS05730	COG0181	hydroxymethylbilane synthase activity
BE24_RS05735	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BE24_RS05740	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
BE24_RS05745	COG0218	Necessary for normal cell division and for the maintenance of normal septation
BE24_RS05750	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
BE24_RS05755	COG0544	peptidyl-prolyl cis-trans isomerase activity
BE24_RS05765	COG4112	unkown
BE24_RS05770	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
BE24_RS05775	COG0291	Belongs to the bacterial ribosomal protein bL35 family
BE24_RS05785	COG0833	amino acid
BE24_RS05790	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BE24_RS05795	COG1484	DNA-dependent DNA replication
BE24_RS05805	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
BE24_RS05810	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BE24_RS05815	COG0237	dephospho-CoA kinase activity
BE24_RS05825	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BE24_RS05825	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BE24_RS05830	COG5002	protein histidine kinase activity
BE24_RS05835	COG0745	RESPONSE REGULATOR receiver
BE24_RS05840	COG0538	isocitrate dehydrogenase activity
BE24_RS05845	COG0372	Belongs to the citrate synthase family
BE24_RS05850	COG1113	amino acid transport
BE24_RS05855	COG0469	pyruvate kinase activity
BE24_RS05860	COG0205	6-phosphofructokinase activity
BE24_RS05865	COG0825	malonyl-CoA metabolic process
BE24_RS05870	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
BE24_RS05875	COG0281	malic enzyme
BE24_RS05880	COG0587	DNA-directed DNA polymerase activity
BE24_RS05885	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
BE24_RS05890	COG4109	DRTGG domain
BE24_RS05900	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
BE24_RS05905	COG0006	proline dipeptidase activity
BE24_RS05910	COG3142	Participates in the control of copper homeostasis
BE24_RS05915	COG0686	Belongs to the AlaDH PNT family
BE24_RS05920	COG0589	response to stress
BE24_RS05930	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
BE24_RS05935	COG0827	DNA restriction-modification system
BE24_RS05940	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
BE24_RS05945	COG1714	RDD family
BE24_RS05950	COG0616	signal peptide processing
BE24_RS05960	COG0301	tRNA thio-modification
BE24_RS05965	COG1104	cysteine desulfurase activity
BE24_RS05970	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
BE24_RS05975	COG1956	GAF domain-containing protein
BE24_RS05980	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
BE24_RS05985	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BE24_RS05990	COG0584	glycerophosphoryl diester phosphodiesterase
BE24_RS05995	COG1764	response to oxidative stress
BE24_RS06000	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
BE24_RS06005	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BE24_RS06015	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BE24_RS06015	COG1263	PTS System
BE24_RS06020	COG0204	Acyl-transferase
BE24_RS06025	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BE24_RS06030	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BE24_RS06045	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BE24_RS06050	COG0454	-acetyltransferase
BE24_RS06055	COG0123	including yeast histone deacetylase and acetoin utilization protein
BE24_RS06065	COG1609	Transcriptional regulator
BE24_RS06070	COG1605	Chorismate mutase
BE24_RS06070	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
BE24_RS06080	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
BE24_RS06085	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BE24_RS06090	COG1674	ftsk spoiiie
BE24_RS06095	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BE24_RS06100	COG4848	Belongs to the UPF0354 family
BE24_RS06105	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BE24_RS06110	COG1363	Peptidase, m42
BE24_RS06120	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BE24_RS06125	COG0220	tRNA (guanine-N7-)-methyltransferase activity
BE24_RS06130	COG0510	thiamine kinase activity
BE24_RS06135	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BE24_RS06140	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BE24_RS06150	COG1187	pseudouridine synthase activity
BE24_RS06155	COG2244	polysaccharide biosynthetic process
BE24_RS06170	COG0495	leucyl-tRNA aminoacylation
BE24_RS06175	COG2814	Major facilitator Superfamily
BE24_RS06180	COG1242	4 iron, 4 sulfur cluster binding
BE24_RS06185	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
BE24_RS06195	COG0039	L-malate dehydrogenase activity
BE24_RS06200	COG2267	carboxylic ester hydrolase activity
BE24_RS06210	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
BE24_RS06215	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BE24_RS06215	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BE24_RS06220	COG0307	riboflavin synthase, alpha
BE24_RS06225	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BE24_RS06225	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BE24_RS06240	COG3266	domain, Protein
BE24_RS06240	COG5632	N-Acetylmuramoyl-L-alanine amidase
BE24_RS06240	COG4193	domain, Protein
BE24_RS06250	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BE24_RS06255	COG0656	L-ascorbic acid biosynthetic process
BE24_RS06265	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
BE24_RS06275	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
BE24_RS06280	COG1506	peptidase
BE24_RS06290	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
BE24_RS06300	COG0318	PFAM AMP-dependent synthetase and ligase
BE24_RS06330	COG0300	oxidoreductase activity
BE24_RS06410	COG3545	Serine hydrolase
BE24_RS06415	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
BE24_RS06420	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
BE24_RS06425	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
BE24_RS06435	COG4473	ABC transporter
BE24_RS06440	COG1131	(ABC) transporter
BE24_RS06445	COG0537	adenosine 5'-monophosphoramidase activity
BE24_RS06460	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BE24_RS06465	COG3481	metal-dependent phosphohydrolase, HD sub domain
BE24_RS06470	COG4717	serine-type aminopeptidase activity
BE24_RS06475	COG0420	3'-5' exonuclease activity
BE24_RS06480	COG3679	Belongs to the UPF0342 family
BE24_RS06485	COG4399	Belongs to the UPF0754 family
BE24_RS06495	COG0788	formyltetrahydrofolate deformylase activity
BE24_RS06510	COG1682	transport, permease protein
BE24_RS06520	COG0730	response to heat
BE24_RS06530	COG0772	Belongs to the SEDS family
BE24_RS06540	COG2801	Transposase and inactivated derivatives
BE24_RS06545	COG1301	dicarboxylic acid transport
BE24_RS06550	COG2197	response regulator
BE24_RS06555	COG2203	Gaf domain
BE24_RS06555	COG4585	Histidine kinase
BE24_RS06560	COG0564	pseudouridine synthase activity
BE24_RS06565	COG0114	fumarate hydratase activity
BE24_RS06580	COG0363	glucosamine-6-phosphate deaminase activity
BE24_RS06590	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
BE24_RS06595	COG1126	abc transporter atp-binding protein
BE24_RS06600	COG0765	amino acid transport
BE24_RS06615	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
BE24_RS06730	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
BE24_RS06735	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BE24_RS06755	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
BE24_RS06760	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BE24_RS06775	COG1098	S1 RNA binding domain
BE24_RS06785	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
BE24_RS06790	COG3956	TIGRFAM MazG family protein
BE24_RS06795	COG2244	polysaccharide biosynthetic process
BE24_RS06800	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BE24_RS06805	COG0193	aminoacyl-tRNA hydrolase activity
BE24_RS06810	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
BE24_RS06815	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BE24_RS06820	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
BE24_RS06825	COG2088	sporulation resulting in formation of a cellular spore
BE24_RS06830	COG0251	oxidation-reduction process
BE24_RS06835	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BE24_RS06840	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
BE24_RS06845	COG4466	Protein conserved in bacteria
BE24_RS06850	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
BE24_RS06855	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
BE24_RS06860	COG0084	hydrolase, TatD family'
BE24_RS06865	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BE24_RS06865	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BE24_RS06870	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
BE24_RS06875	COG2827	Endonuclease containing a URI domain
BE24_RS06880	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
BE24_RS06885	COG4467	Involved in initiation control of chromosome replication
BE24_RS06890	COG1774	PSP1 C-terminal conserved region
BE24_RS06895	COG0470	DNA polymerase III
BE24_RS06900	COG3870	Protein conserved in bacteria
BE24_RS06905	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
BE24_RS06910	COG1982	Orn Lys Arg decarboxylase major
BE24_RS06940	COG0735	belongs to the Fur family
BE24_RS06945	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BE24_RS06950	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BE24_RS06955	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
BE24_RS06960	COG4129	membrane
BE24_RS06970	COG3557	Belongs to the UPF0374 family
BE24_RS06980	COG1988	membrane-bound metal-dependent
BE24_RS06990	COG1134	teichoic acid transport
BE24_RS07005	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BE24_RS07010	COG0693	protein deglycase activity
BE24_RS07020	COG0535	radical SAM domain protein
BE24_RS07025	COG1607	acyl-coa hydrolase
BE24_RS07030	COG2309	aminopeptidase activity
BE24_RS07035	COG4840	Belongs to the UPF0435 family
BE24_RS07040	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BE24_RS07050	COG1295	ribonuclease BN
BE24_RS07055	COG2197	response regulator
BE24_RS07060	COG4585	Histidine kinase
BE24_RS07075	COG0024	Methionine aminopeptidase
BE24_RS07080	COG4129	membrane
BE24_RS07095	COG1528	Iron-storage protein
BE24_RS07105	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BE24_RS07115	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BE24_RS07120	COG1597	lipid kinase activity
BE24_RS07125	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BE24_RS07130	COG0154	amidase activity
BE24_RS07135	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BE24_RS07140	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BE24_RS07145	COG4851	CamS sex pheromone cAM373 precursor
BE24_RS07150	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
BE24_RS07160	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
BE24_RS07165	COG1876	peptidase activity
BE24_RS07170	COG4496	protein, YerC YecD
BE24_RS07175	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BE24_RS07185	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
BE24_RS07190	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
BE24_RS07195	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
BE24_RS07205	COG0077	Prephenate dehydratase
BE24_RS07210	COG0471	metal ion transport
BE24_RS07220	COG1335	isochorismatase
BE24_RS07225	COG1227	inorganic diphosphatase activity
BE24_RS07230	COG1012	belongs to the aldehyde dehydrogenase family
BE24_RS07235	COG2706	6-phosphogluconolactonase activity
BE24_RS07275	COG1131	(ABC) transporter
BE24_RS07290	COG1725	Transcriptional regulator
BE24_RS07310	COG0459	protein refolding
BE24_RS07315	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
BE24_RS07335	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BE24_RS07340	COG4512	PFAM Accessory gene regulator B
BE24_RS07350	COG3290	protein histidine kinase activity
BE24_RS07355	COG3279	Response regulator of the LytR AlgR family
BE24_RS07360	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BE24_RS07365	COG1621	beta-fructofuranosidase activity
BE24_RS07370	COG1609	Transcriptional regulator
BE24_RS07375	COG0425	Belongs to the sulfur carrier protein TusA family
BE24_RS07380	COG2391	methyltransferase activity
BE24_RS07385	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
BE24_RS07390	COG0488	(ABC) transporter
BE24_RS07400	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
BE24_RS07410	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
BE24_RS07415	COG0456	acetyltransferase
BE24_RS07420	COG1214	PFAM Peptidase M22, glycoprotease
BE24_RS07425	COG0802	atpase or kinase
BE24_RS07430	COG0129	dihydroxy-acid dehydratase activity
BE24_RS07435	COG0028	Belongs to the TPP enzyme family
BE24_RS07440	COG0440	acetolactate synthase activity
BE24_RS07445	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
BE24_RS07450	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BE24_RS07455	COG0473	3-isopropylmalate dehydrogenase activity
BE24_RS07460	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
BE24_RS07465	COG0066	3-isopropylmalate dehydratase activity
BE24_RS07470	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BE24_RS07515	COG3091	SprT-like family
BE24_RS07520	COG2183	response to ionizing radiation
BE24_RS07525	COG1191	sigma factor activity
BE24_RS07540	COG2208	phosphoserine phosphatase activity
BE24_RS07545	COG2337	Toxic component of a toxin-antitoxin (TA) module
BE24_RS07555	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BE24_RS07570	COG3428	Bacterial PH domain
BE24_RS07580	COG0513	Belongs to the DEAD box helicase family
BE24_RS07585	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BE24_RS07590	COG1181	Belongs to the D-alanine--D-alanine ligase family
BE24_RS07595	COG0772	Belongs to the SEDS family
BE24_RS07605	COG1937	Protein conserved in bacteria
BE24_RS07615	COG1418	mRNA catabolic process
BE24_RS07620	COG0706	membrane insertase activity
BE24_RS07625	COG0352	thiamine-phosphate diphosphorylase activity
BE24_RS07630	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
BE24_RS07640	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
BE24_RS07645	COG1388	LysM domain
BE24_RS07650	COG0629	single-stranded DNA binding
BE24_RS07660	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BE24_RS07665	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BE24_RS07675	COG0355	proton-transporting ATP synthase activity, rotational mechanism
BE24_RS07680	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
BE24_RS07685	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
BE24_RS07690	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
BE24_RS07695	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BE24_RS07700	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
BE24_RS07705	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BE24_RS07710	COG0356	it plays a direct role in the translocation of protons across the membrane
BE24_RS07720	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
BE24_RS07725	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
BE24_RS07730	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
BE24_RS07735	COG4475	Protein of unknown function (DUF436)
BE24_RS07740	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BE24_RS07745	COG0009	L-threonylcarbamoyladenylate synthase
BE24_RS07750	COG2890	protein-(glutamine-N5) methyltransferase activity
BE24_RS07755	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
BE24_RS07760	COG1435	thymidine kinase activity
BE24_RS07765	COG0254	rRNA binding
BE24_RS07770	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
BE24_RS07775	COG1012	belongs to the aldehyde dehydrogenase family
BE24_RS07785	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BE24_RS07790	COG0191	fructose-bisphosphate aldolase activity
BE24_RS07795	COG0504	CTP synthase activity
BE24_RS07805	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BE24_RS07810	COG5146	pantothenate kinase activity
BE24_RS07830	COG1854	S-ribosylhomocysteine lyase activity
BE24_RS07840	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
BE24_RS07845	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
BE24_RS07850	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
BE24_RS07855	COG0813	purine-nucleoside phosphorylase activity
BE24_RS07860	COG0783	Belongs to the Dps family
BE24_RS07865	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BE24_RS07880	COG2855	membrane
BE24_RS07890	COG1482	cell wall glycoprotein biosynthetic process
BE24_RS07895	COG2186	Transcriptional regulator
BE24_RS07900	COG0702	epimerase
BE24_RS07905	COG0640	Transcriptional regulator
BE24_RS07940	COG1119	ATPase activity
BE24_RS07980	COG2213	PTS system mannitol-specific
BE24_RS07985	COG3711	transcriptional antiterminator
BE24_RS07995	COG0246	Mannitol dehydrogenase
BE24_RS08000	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BE24_RS08010	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
BE24_RS08075	COG0489	protein tyrosine kinase activity
BE24_RS08090	COG1272	protein, Hemolysin III
BE24_RS08095	COG4284	Utp--glucose-1-phosphate uridylyltransferase
BE24_RS08100	COG1988	membrane-bound metal-dependent
BE24_RS08110	COG2329	Antibiotic biosynthesis monooxygenase
BE24_RS08115	COG3314	Sporulation integral membrane protein YlbJ
BE24_RS08120	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BE24_RS08125	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BE24_RS08130	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
BE24_RS08135	COG3457	Alanine racemase
BE24_RS08140	COG4264	IucA IucC family
BE24_RS08145	COG2814	Major facilitator Superfamily
BE24_RS08150	COG4264	IucA IucC family
BE24_RS08155	COG1302	Protein conserved in bacteria
BE24_RS08170	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BE24_RS08175	COG0604	alcohol dehydrogenase
BE24_RS08180	COG2130	NADP-dependent
BE24_RS08185	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BE24_RS08195	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
BE24_RS08200	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
BE24_RS08205	COG0101	tRNA pseudouridine synthase activity
BE24_RS08215	COG1122	ATPase activity
BE24_RS08220	COG1122	ATPase activity
BE24_RS08225	COG0203	ribosomal protein L17
BE24_RS08230	COG0202	RNA polymerase activity
BE24_RS08235	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
BE24_RS08240	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
BE24_RS08245	COG0257	Belongs to the bacterial ribosomal protein bL36 family
BE24_RS08260	COG0201	protein transport
BE24_RS08265	COG0200	Binds to the 23S rRNA
BE24_RS08270	COG1841	ribosomal large subunit assembly
BE24_RS08275	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
BE24_RS08280	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
BE24_RS08285	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
BE24_RS08290	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
BE24_RS08295	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
BE24_RS08300	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
BE24_RS08305	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
BE24_RS08310	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
BE24_RS08315	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
BE24_RS08320	COG0255	Belongs to the universal ribosomal protein uL29 family
BE24_RS08325	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
BE24_RS08330	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
BE24_RS08335	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
BE24_RS08340	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
BE24_RS08345	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
BE24_RS08350	COG0089	rRNA binding
BE24_RS08355	COG0088	Forms part of the polypeptide exit tunnel
BE24_RS08360	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
BE24_RS08365	COG0051	transcription antitermination factor activity, RNA binding
BE24_RS08375	COG2252	PERMEase
BE24_RS08380	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BE24_RS08380	COG0551	DNA topoisomerase type I activity
BE24_RS08390	COG4975	Glucose uptake
BE24_RS08415	COG2348	transferase activity, transferring amino-acyl groups
BE24_RS08445	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BE24_RS08450	COG0746	molybdenum cofactor guanylyltransferase activity
BE24_RS08475	COG0315	cyclic pyranopterin monophosphate synthase activity
BE24_RS08480	COG0521	Mo-molybdopterin cofactor biosynthetic process
BE24_RS08485	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BE24_RS08490	COG1510	regulation of RNA biosynthetic process
BE24_RS08495	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
BE24_RS08500	COG4149	molybdate abc transporter
BE24_RS08505	COG0725	ABC transporter, periplasmic molybdate-binding protein
BE24_RS08510	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
BE24_RS08515	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BE24_RS08520	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
BE24_RS08525	COG1609	Transcriptional regulator
BE24_RS08530	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
BE24_RS08540	COG1268	BioY protein
BE24_RS08545	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BE24_RS08550	COG1960	acyl-CoA dehydrogenase activity
BE24_RS08555	COG1126	abc transporter atp-binding protein
BE24_RS08560	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BE24_RS08565	COG0765	amino acid transport
BE24_RS08570	COG0765	amino acid transport
BE24_RS08595	COG3942	CHAP domain
BE24_RS08600	COG1757	Na H antiporter
BE24_RS08615	COG3942	CHAP domain
BE24_RS08620	COG2076	Multidrug Resistance protein
BE24_RS08625	COG2076	Multidrug Resistance protein
BE24_RS08630	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BE24_RS08655	COG3383	formate dehydrogenase (NAD+) activity
BE24_RS08660	COG1316	TRANSCRIPTIONal
BE24_RS08685	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
BE24_RS08690	COG1263	PTS System
BE24_RS08690	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BE24_RS08700	COG1785	Belongs to the alkaline phosphatase family
BE24_RS08705	COG1113	amino acid transport
BE24_RS08730	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BE24_RS08735	COG0385	Bile acid
BE24_RS08745	COG1263	PTS System
BE24_RS08745	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BE24_RS08765	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BE24_RS08770	COG1028	Short-chain dehydrogenase reductase Sdr
BE24_RS08775	COG1473	amidohydrolase
BE24_RS08780	COG0659	secondary active sulfate transmembrane transporter activity
BE24_RS08785	COG1228	amidohydrolase
BE24_RS08790	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
BE24_RS08795	COG3314	Sporulation integral membrane protein YlbJ
BE24_RS08800	COG0583	DNA-binding transcription factor activity
BE24_RS08805	COG0010	Belongs to the arginase family
BE24_RS08810	COG1266	CAAX protease self-immunity
BE24_RS08815	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
BE24_RS08820	COG2258	MOSC domain
BE24_RS08825	COG2017	converts alpha-aldose to the beta-anomer
BE24_RS08830	COG1668	transmembrane transport
BE24_RS08835	COG4152	abc transporter atp-binding protein
BE24_RS08840	COG1069	ribulokinase activity
BE24_RS08845	COG3152	Membrane
BE24_RS08850	COG2094	Belongs to the DNA glycosylase MPG family
BE24_RS08855	COG1757	Na H antiporter
BE24_RS08860	COG0786	glutamate:sodium symporter activity
BE24_RS08865	COG1304	FMN binding
BE24_RS08870	COG0598	Magnesium transport protein CorA
BE24_RS08895	COG2814	Major facilitator Superfamily
BE24_RS08900	COG1566	PFAM secretion protein HlyD family protein
BE24_RS08910	COG2814	Major facilitator Superfamily
BE24_RS08915	COG4640	response to antibiotic
BE24_RS08930	COG1136	(ABC) transporter
BE24_RS08935	COG0577	efflux transmembrane transporter activity
BE24_RS08940	COG0745	RESPONSE REGULATOR receiver
BE24_RS08945	COG5002	protein histidine kinase activity
BE24_RS08945	COG3850	Histidine kinase
BE24_RS08955	COG0438	transferase activity, transferring glycosyl groups
BE24_RS08960	COG1620	l-lactate permease
BE24_RS08980	COG0604	alcohol dehydrogenase
BE24_RS08985	COG2814	Major facilitator Superfamily
BE24_RS08995	COG0492	ferredoxin-NADP+ reductase activity
BE24_RS09005	COG0698	ribose 5-phosphate isomerase
BE24_RS09015	COG2376	Dihydroxyacetone kinase
BE24_RS09020	COG1063	alcohol dehydrogenase
BE24_RS09025	COG1349	DNA-binding transcription factor activity
BE24_RS09030	COG1288	antiporter activity
BE24_RS09035	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BE24_RS09040	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BE24_RS09045	COG1028	Short-chain dehydrogenase reductase Sdr
BE24_RS09050	COG1283	sodium-dependent phosphate transmembrane transporter activity
BE24_RS09070	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BE24_RS09070	COG1263	PTS System
BE24_RS09095	COG1846	Transcriptional regulator
BE24_RS09110	COG2223	nitrite transmembrane transporter activity
BE24_RS09120	COG4585	Histidine kinase
BE24_RS09140	COG1140	nitrate reductase beta subunit
BE24_RS09145	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
BE24_RS09160	COG2146	nitrite reductase [NAD(P)H] activity
BE24_RS09165	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BE24_RS09180	COG0454	-acetyltransferase
BE24_RS09185	COG2116	formate transmembrane transporter activity
BE24_RS09190	COG2188	Transcriptional regulator
BE24_RS09195	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BE24_RS09195	COG2190	(PTS) system
BE24_RS09195	COG1263	PTS System
BE24_RS09220	COG1695	Transcriptional regulator
BE24_RS09230	COG2353	YceI-like domain
BE24_RS09235	COG3443	Belongs to the bacterial solute-binding protein 9 family
BE24_RS09235	COG0803	Belongs to the bacterial solute-binding protein 9 family
BE24_RS09240	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BE24_RS09255	COG2814	Major facilitator Superfamily
BE24_RS09260	COG0588	phosphoglycerate mutase activity
BE24_RS09265	COG1388	LysM domain
BE24_RS09270	COG2801	Transposase and inactivated derivatives
BE24_RS09280	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BE24_RS09290	COG2814	Major facilitator Superfamily
BE24_RS09310	COG0025	NhaP-type Na H and K H
BE24_RS09315	COG0706	membrane insertase activity
BE24_RS09325	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
BE24_RS09345	COG4187	Peptidase family M20/M25/M40
BE24_RS09355	COG3275	phosphorelay sensor kinase activity
BE24_RS09360	COG3279	Response regulator of the LytR AlgR family
BE24_RS09365	COG1380	Effector of murein hydrolase LrgA
BE24_RS09370	COG1346	cytolysis
BE24_RS09380	COG1174	glycine betaine transport
BE24_RS09390	COG1174	glycine betaine transport
BE24_RS09405	COG1250	3-hydroxyacyl-CoA dehydrogenase
BE24_RS09410	COG3246	L-lysine catabolic process to acetate
BE24_RS09415	COG1309	transcriptional regulator
BE24_RS09420	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
BE24_RS09425	COG0531	amino acid
BE24_RS09430	COG2851	Citrate transporter
BE24_RS09435	COG2814	Major facilitator Superfamily
BE24_RS09440	COG0390	transport system, permease component
BE24_RS09445	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BE24_RS09455	COG0069	glutamate synthase activity
BE24_RS09465	COG1363	Peptidase, m42
BE24_RS09470	COG1028	Short-chain dehydrogenase reductase Sdr
BE24_RS09475	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
BE24_RS09485	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
BE24_RS09490	COG3048	D-serine ammonia-lyase activity
BE24_RS09500	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
BE24_RS09505	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
BE24_RS09510	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BE24_RS09515	COG0131	Imidazoleglycerol-phosphate dehydratase
BE24_RS09520	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
BE24_RS09525	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
BE24_RS09530	COG0107	imidazoleglycerol-phosphate synthase activity
BE24_RS09560	COG4221	oxidoreductase activity
BE24_RS09580	COG1904	glucuronate isomerase
BE24_RS09585	COG2211	Major facilitator Superfamily
BE24_RS09610	COG2211	Major facilitator Superfamily
BE24_RS09620	COG3949	Membrane
BE24_RS09625	COG1028	Short-chain dehydrogenase reductase Sdr
BE24_RS09630	COG2610	gluconate transmembrane transporter activity
BE24_RS09635	COG1070	Carbohydrate kinase
BE24_RS09640	COG1802	Transcriptional regulator
BE24_RS09650	COG2357	RelA SpoT domain protein
BE24_RS09670	COG1289	transmembrane transporter activity
BE24_RS09675	COG3527	Alpha-acetolactate decarboxylase
BE24_RS09685	COG2271	Major facilitator Superfamily
BE24_RS09690	COG0586	Pfam SNARE associated Golgi protein
BE24_RS09695	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BE24_RS09700	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
BE24_RS09710	COG3949	Membrane
BE24_RS09715	COG0471	metal ion transport
BE24_RS09725	COG0400	carboxylic ester hydrolase activity
BE24_RS09730	COG0346	lactoylglutathione lyase activity
BE24_RS09735	COG0346	lactoylglutathione lyase activity
BE24_RS09740	COG1846	Transcriptional regulator
BE24_RS09745	COG1012	belongs to the aldehyde dehydrogenase family
BE24_RS09760	COG1132	(ABC) transporter
BE24_RS09765	COG1132	(ABC) transporter
BE24_RS09775	COG2514	catechol 2,3-dioxygenase activity
BE24_RS09780	COG0778	Nitroreductase
BE24_RS09785	COG0561	phosphatase activity
BE24_RS09790	COG2249	NAD(P)H dehydrogenase (quinone) activity
BE24_RS09795	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BE24_RS09800	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BE24_RS09810	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BE24_RS09815	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
BE24_RS09820	COG3764	Sortase (surface protein transpeptidase)
BE24_RS09830	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BE24_RS09850	COG1129	ABC transporter
BE24_RS09870	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
BE24_RS09875	COG1063	alcohol dehydrogenase
BE24_RS09880	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
BE24_RS09905	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
BE24_RS09920	COG0657	acetylesterase activity
BE24_RS09940	COG2515	1-aminocyclopropane-1-carboxylate deaminase
BE24_RS09955	COG2190	(PTS) system
BE24_RS09955	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BE24_RS09955	COG1263	PTS System
BE24_RS09960	COG1288	antiporter activity
BE24_RS09965	COG0028	Belongs to the TPP enzyme family
BE24_RS09975	COG1380	Effector of murein hydrolase LrgA
BE24_RS09980	COG0583	DNA-binding transcription factor activity
BE24_RS09985	COG1757	Na H antiporter
BE24_RS09990	COG3942	CHAP domain
BE24_RS09995	COG3386	PFAM SMP-30 Gluconolaconase
BE24_RS10010	COG3425	synthase
BE24_RS10020	COG3655	Transcriptional regulator
BE24_RS10025	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BE24_RS10050	COG1473	amidohydrolase
BE24_RS10065	COG2409	Drug exporters of the RND superfamily
BE24_RS10075	COG1012	belongs to the aldehyde dehydrogenase family
BE24_RS10080	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
BE24_RS10090	COG4336	lyase activity
BE24_RS10105	COG5505	Protein of unknown function (DUF819)
BE24_RS10110	COG0471	metal ion transport
BE24_RS10120	COG1028	Short-chain dehydrogenase reductase Sdr
BE24_RS10125	COG0577	efflux transmembrane transporter activity
BE24_RS10130	COG1136	(ABC) transporter
BE24_RS10135	COG0659	secondary active sulfate transmembrane transporter activity
BE24_RS10140	COG2217	Heavy metal translocating P-type atpase
BE24_RS10145	COG2608	mercury ion transmembrane transporter activity
BE24_RS10155	COG0436	Aminotransferase
BE24_RS10160	COG1388	LysM domain
BE24_RS10175	COG3189	MarR family transcriptional regulator
BE24_RS10190	COG1113	amino acid transport
BE24_RS10195	COG0697	spore germination
BE24_RS10220	COG3001	Fructosamine kinase
BE24_RS10225	COG0167	dihydroorotate dehydrogenase activity
BE24_RS10235	COG0561	phosphatase activity
BE24_RS10245	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BE24_RS10250	COG0531	amino acid
BE24_RS10260	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BE24_RS10285	COG0747	negative chemotaxis
BE24_RS10290	COG4413	Urea transporter
BE24_RS10295	COG0831	urea catabolic process
BE24_RS10300	COG0832	Belongs to the urease beta subunit family
BE24_RS10305	COG0804	urea catabolic process
BE24_RS10310	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
BE24_RS10315	COG0830	nickel cation binding
BE24_RS10320	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
BE24_RS10325	COG0829	nickel cation binding
BE24_RS10350	COG0626	cystathionine gamma-synthase activity
BE24_RS10355	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BE24_RS10375	COG1940	carbohydrate kinase activity
BE24_RS10380	COG1482	cell wall glycoprotein biosynthetic process
BE24_RS10390	COG3711	transcriptional antiterminator
BE24_RS10390	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BE24_RS10405	COG0039	L-malate dehydrogenase activity
BE24_RS10410	COG1464	Belongs to the NlpA lipoprotein family
BE24_RS10420	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BE24_RS10430	COG4297	protein containing double-stranded beta helix domain
BE24_RS10435	COG3037	sugar-specific permease SgaT UlaA
BE24_RS10445	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BE24_RS10450	COG3711	transcriptional antiterminator
BE24_RS10455	COG1126	abc transporter atp-binding protein
BE24_RS10460	COG0765	amino acid transport
BE24_RS10465	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BE24_RS10480	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BE24_RS10485	COG0363	glucosamine-6-phosphate deaminase activity
BE24_RS10490	COG1263	PTS System
BE24_RS10490	COG2190	(PTS) system
BE24_RS10490	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BE24_RS10495	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
BE24_RS10500	COG2814	Major facilitator Superfamily
BE24_RS10505	COG1620	l-lactate permease
BE24_RS10510	COG1063	alcohol dehydrogenase
BE24_RS10515	COG2610	gluconate transmembrane transporter activity
BE24_RS10530	COG0431	NADPH-dependent FMN reductase
BE24_RS10540	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BE24_RS10545	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
BE24_RS10550	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
BE24_RS10555	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
BE24_RS10560	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BE24_RS10565	COG0531	amino acid
BE24_RS10570	COG0477	Major facilitator Superfamily
BE24_RS10580	COG2843	Capsule synthesis protein
BE24_RS10585	COG0778	Nitroreductase
BE24_RS10610	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
BE24_RS10615	COG1012	belongs to the aldehyde dehydrogenase family
BE24_RS10620	COG1510	regulation of RNA biosynthetic process
BE24_RS10625	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BE24_RS10645	COG0531	amino acid
BE24_RS10650	COG1012	belongs to the aldehyde dehydrogenase family
BE24_RS10655	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BE24_RS10660	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BE24_RS10670	COG2807	transmembrane transport
BE24_RS10675	COG1476	TRANSCRIPTIONal
BE24_RS10695	COG2764	glyoxalase bleomycin resistance protein dioxygenase
BE24_RS10700	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
BE24_RS10705	COG0574	Belongs to the PEP-utilizing enzyme family
BE24_RS10705	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BE24_RS10710	COG3835	regulator
BE24_RS10715	COG1929	Belongs to the glycerate kinase type-1 family
BE24_RS10725	COG3875	lactate racemase activity
BE24_RS10730	COG1606	tRNA processing
BE24_RS10735	COG1691	(AIR) carboxylase
BE24_RS10740	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
BE24_RS10745	COG0673	inositol 2-dehydrogenase activity
BE24_RS10785	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BE24_RS10795	COG3961	Belongs to the TPP enzyme family
BE24_RS10800	COG1846	Transcriptional regulator
BE24_RS10805	COG0668	transmembrane transport
BE24_RS10815	COG0584	glycerophosphoryl diester phosphodiesterase
BE24_RS10825	COG2814	Major facilitator Superfamily
BE24_RS10845	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
BE24_RS10870	COG0579	oxidoreductase
BE24_RS10875	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
BE24_RS10880	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
BE24_RS10915	COG2084	Dehydrogenase
BE24_RS10920	COG2188	Transcriptional regulator
BE24_RS10925	COG0346	lactoylglutathione lyase activity
BE24_RS10950	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
BE24_RS10955	COG0602	queuosine metabolic process
BE24_RS10960	COG1328	CTP reductase activity
BE24_RS10965	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BE24_RS10970	COG2022	thiamine diphosphate biosynthetic process
BE24_RS10980	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BE24_RS10985	COG0352	thiamine-phosphate diphosphorylase activity
BE24_RS10990	COG1070	Carbohydrate kinase
BE24_RS11010	COG1917	Cupin 2, conserved barrel domain protein
BE24_RS11010	COG2207	Transcriptional regulator
BE24_RS11030	COG1940	carbohydrate kinase activity
BE24_RS11030	COG1846	Transcriptional regulator
BE24_RS11035	COG2115	Belongs to the xylose isomerase family
BE24_RS11040	COG1070	Carbohydrate kinase
BE24_RS11045	COG2814	Major facilitator Superfamily
BE24_RS11045	COG0477	Major facilitator Superfamily
BE24_RS11050	COG3479	Phenolic acid decarboxylase
BE24_RS11055	COG1695	Transcriptional regulator
BE24_RS11065	COG1131	(ABC) transporter
BE24_RS11080	COG2160	L-arabinose isomerase activity
BE24_RS11085	COG0235	Class ii aldolase
BE24_RS11095	COG1609	Transcriptional regulator
BE24_RS11100	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BE24_RS11100	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BE24_RS11105	COG1054	Belongs to the UPF0176 family
BE24_RS11110	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BE24_RS11115	COG1388	LysM domain
BE24_RS11120	COG1388	LysM domain
BE24_RS11125	COG5002	protein histidine kinase activity
BE24_RS11145	COG2318	DinB family
BE24_RS11155	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BE24_RS11160	COG1012	belongs to the aldehyde dehydrogenase family
BE24_RS11170	COG1028	Short-chain dehydrogenase reductase Sdr
BE24_RS11175	COG3192	ethanolamine utilization protein
BE24_RS11220	COG3414	Phosphotransferase system galactitol-specific IIB component
BE24_RS11225	COG3775	system Galactitol-specific IIC component
BE24_RS11230	COG1063	alcohol dehydrogenase
BE24_RS11235	COG1063	alcohol dehydrogenase
BE24_RS11240	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BE24_RS11245	COG1028	Short-chain dehydrogenase reductase Sdr
BE24_RS11250	COG1695	Transcriptional regulator
BE24_RS11265	COG0463	Glycosyl transferase, family 2
BE24_RS11270	COG2814	Major facilitator Superfamily
BE24_RS11295	COG2814	Major facilitator Superfamily
BE24_RS11300	COG3250	beta-galactosidase activity
BE24_RS11305	COG2211	Major facilitator Superfamily
BE24_RS11310	COG2207	Transcriptional regulator
BE24_RS11315	COG0583	DNA-binding transcription factor activity
BE24_RS11345	COG1124	(ABC) transporter
BE24_RS11350	COG0444	Belongs to the ABC transporter superfamily
BE24_RS11360	COG0601	transmembrane transport
BE24_RS11385	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
BE24_RS11390	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
BE24_RS11405	COG2723	6-phospho-beta-galactosidase activity
BE24_RS11410	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BE24_RS11410	COG1263	PTS System
BE24_RS11415	COG3711	transcriptional antiterminator
BE24_RS11430	COG0415	Belongs to the DNA photolyase family
BE24_RS11465	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
BE24_RS11470	COG0702	epimerase
BE24_RS11480	COG2814	Major facilitator Superfamily
BE24_RS11485	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BE24_RS11490	COG1136	(ABC) transporter
BE24_RS11500	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
BE24_RS11505	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
BE24_RS11515	COG1942	4-Oxalocrotonate Tautomerase
BE24_RS11520	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BE24_RS11550	COG3181	Tripartite tricarboxylate transporter family receptor
BE24_RS11560	COG0583	DNA-binding transcription factor activity
BE24_RS11585	COG3732	PTS system glucitol sorbitol-specific
BE24_RS11600	COG3711	transcriptional antiterminator
BE24_RS11600	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BE24_RS11675	COG1388	LysM domain
BE24_RS11685	COG0702	epimerase
BE24_RS11695	COG0789	Transcriptional regulator
BE24_RS11750	COG1316	TRANSCRIPTIONal
BE24_RS11755	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BE24_RS11765	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BE24_RS11800	COG1045	serine acetyltransferase
BE24_RS11845	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
BE24_RS11850	COG0732	type I restriction modification DNA specificity domain
BE24_RS11855	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
BE24_RS11920	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
BE24_RS11925	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
BE24_RS11940	COG5002	protein histidine kinase activity
BE24_RS11945	COG0745	RESPONSE REGULATOR receiver
BE24_RS11960	COG1819	glycosyl
BE24_RS11965	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
BE24_RS11970	COG0305	Participates in initiation and elongation during chromosome replication
BE24_RS11975	COG0359	binds to the 23S rRNA
BE24_RS11980	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
BE24_RS11990	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BE24_RS12000	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
BE24_RS12005	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
BE24_RS12010	COG2986	histidine ammonia-lyase
BE24_RS12015	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
BE24_RS12020	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BE24_RS12030	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
BE24_RS12035	COG2501	S4 domain
BE24_RS12040	COG0592	DNA-directed DNA polymerase activity
BE24_RS12045	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
BE24_RS12055	COG0594	ribonuclease P activity
BE24_RS12060	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
BE24_RS12065	COG0445	tRNA wobble uridine modification
BE24_RS12070	COG0357	Ribosomal RNA small subunit methyltransferase G
BE24_RS12080	COG1966	Carbon starvation protein
BE24_RS12085	COG2271	Major facilitator Superfamily
BE24_RS12095	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BE24_RS12100	COG0450	alkyl hydroperoxide reductase
BE24_RS12110	COG0789	Transcriptional regulator
BE24_RS12130	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BE24_RS12135	COG0656	L-ascorbic acid biosynthetic process
BE24_RS12140	COG0531	amino acid
BE24_RS12145	COG1028	Short-chain dehydrogenase reductase Sdr
BE24_RS12165	COG0463	Glycosyl transferase, family 2
BE24_RS12165	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
BE24_RS12170	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
BE24_RS12170	COG0463	Glycosyl transferase, family 2
BE24_RS12195	COG1607	acyl-coa hydrolase
BE24_RS12200	COG0583	DNA-binding transcription factor activity
BE24_RS12205	COG0561	phosphatase activity
BE24_RS12225	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BE24_RS12230	COG0803	Belongs to the bacterial solute-binding protein 9 family
BE24_RS12235	COG2239	Acts as a magnesium transporter
BE24_RS12245	COG0318	PFAM AMP-dependent synthetase and ligase
BE24_RS12250	COG1960	acyl-CoA dehydrogenase activity
BE24_RS12260	COG0183	Belongs to the thiolase family
BE24_RS12285	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
BE24_RS12295	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
BE24_RS12300	COG0646	methionine synthase
BE24_RS12300	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
BE24_RS12305	COG0626	cystathionine gamma-synthase activity
BE24_RS12310	COG0626	cystathionine gamma-synthase activity
BE24_RS12315	COG1475	DNA binding
BE24_RS12320	COG0175	sulfate reduction
BE24_RS12325	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
BE24_RS12330	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BE24_RS12350	COG0730	response to heat
BE24_RS12355	COG2046	Belongs to the sulfate adenylyltransferase family
BE24_RS12360	COG0529	Catalyzes the synthesis of activated sulfate
BE24_RS12370	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
BE24_RS12375	COG2226	methyltransferase
BE24_RS12380	COG0772	Belongs to the SEDS family
BE24_RS12395	COG2814	Major facilitator Superfamily
BE24_RS12400	COG3759	membrane
BE24_RS12405	COG2030	dehydratase
BE24_RS12410	COG1733	regulation of RNA biosynthetic process
BE24_RS12415	COG2814	Major facilitator Superfamily
BE24_RS12420	COG1473	amidohydrolase
BE24_RS12425	COG2814	Major facilitator Superfamily
BE24_RS12430	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BE24_RS12445	COG1012	belongs to the aldehyde dehydrogenase family
BE24_RS12465	COG4978	Transcriptional regulator
BE24_RS12465	COG0789	Transcriptional regulator
BE24_RS12475	COG1288	antiporter activity
BE24_RS12485	COG1136	(ABC) transporter
BE24_RS12490	COG0577	efflux transmembrane transporter activity
BE24_RS12505	COG1454	alcohol dehydrogenase
BE24_RS12510	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
BE24_RS12515	COG1064	alcohol dehydrogenase
BE24_RS12520	COG2084	Dehydrogenase
BE24_RS12530	COG2610	gluconate transmembrane transporter activity
BE24_RS12535	COG2211	Major facilitator Superfamily
BE24_RS12540	COG1486	melibiose metabolic process
BE24_RS12545	COG1917	Cupin 2, conserved barrel domain protein
BE24_RS12545	COG2207	Transcriptional regulator
BE24_RS12550	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BE24_RS12555	COG3002	Belongs to the UPF0753 family
BE24_RS12560	COG5609	conserved protein (DUF2294)
BE24_RS12565	COG0668	transmembrane transport
BE24_RS12570	COG0012	GTP binding
BE24_RS12580	COG0360	Binds together with S18 to 16S ribosomal RNA
BE24_RS12610	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
BE24_RS12620	COG0730	response to heat
BE24_RS12625	COG1937	Protein conserved in bacteria
BE24_RS12630	COG2210	Belongs to the sulfur carrier protein TusA family
BE24_RS12635	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BE24_RS12650	COG4193	domain, Protein
BE24_RS12650	COG3266	domain, Protein
BE24_RS12650	COG5632	N-Acetylmuramoyl-L-alanine amidase
BE24_RS12660	COG0583	DNA-binding transcription factor activity
BE24_RS12685	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BE24_RS12690	COG4195	phage-related replication protein
BE24_RS12705	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BE24_RS12720	COG2076	Multidrug Resistance protein
BE24_RS12725	COG2076	Multidrug Resistance protein
BE24_RS12730	COG1280	lysine exporter protein (LysE YggA)
BE24_RS12750	COG0406	alpha-ribazole phosphatase activity
BE24_RS12765	COG3634	alkyl hydroperoxide reductase activity
BE24_RS12770	COG0450	alkyl hydroperoxide reductase
BE24_RS12775	COG0753	catalase activity
BE24_RS12780	COG0778	Nitroreductase
BE24_RS12795	COG1760	l-serine dehydratase
BE24_RS12800	COG1760	l-serine dehydratase
BE24_RS12805	COG1823	symporter activity
BE24_RS12810	COG5183	chlorophyll binding
BE24_RS12825	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BE24_RS12830	COG2233	PERMEase
BE24_RS12835	COG0516	GMP reductase activity
BE24_RS12835	COG0517	IMP dehydrogenase activity
BE24_RS12840	COG0519	Catalyzes the synthesis of GMP from XMP
BE24_RS12840	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BE24_RS12845	COG0582	viral genome integration into host DNA
BE24_RS12945	COG1301	dicarboxylic acid transport
BE24_RS12960	COG2814	Major facilitator Superfamily
BE24_RS12965	COG0456	acetyltransferase
BE24_RS12965	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
BE24_RS12970	COG2508	Transcriptional regulator
BE24_RS12975	COG1953	Uracil, thiamine, allantoin
BE24_RS12980	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BE24_RS12990	COG0753	catalase activity
BE24_RS12995	COG1876	peptidase activity
BE24_RS13010	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BE24_RS13020	COG1595	DNA-templated transcription, initiation
BE24_RS13030	COG0406	alpha-ribazole phosphatase activity
BE24_RS13035	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BE24_RS13045	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BE24_RS13050	COG3257	ureidoglycine aminohydrolase activity
BE24_RS13055	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
BE24_RS13060	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
BE24_RS13065	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
BE24_RS13070	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
BE24_RS13085	COG2807	transmembrane transport
BE24_RS13090	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
BE24_RS13095	COG4195	phage-related replication protein
BE24_RS13110	COG0789	Transcriptional regulator
BE24_RS13135	COG2268	Band 7 protein
BE24_RS13140	COG5646	InterPro IPR014922
BE24_RS13145	COG1114	Component of the transport system for branched-chain amino acids
BE24_RS13150	COG0733	neurotransmitter:sodium symporter activity
BE24_RS13165	COG0129	dihydroxy-acid dehydratase activity
BE24_RS13175	COG3942	CHAP domain
BE24_RS13175	COG1388	LysM domain
BE24_RS13185	COG0494	nUDIX hydrolase
BE24_RS13190	COG0004	ammonium transporteR
BE24_RS13210	COG0067	glutamate synthase
BE24_RS13210	COG0069	glutamate synthase activity
BE24_RS13210	COG0070	glutamate synthase
BE24_RS13215	COG0493	'glutamate synthase
BE24_RS13225	COG1263	PTS System
BE24_RS13225	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BE24_RS13230	COG0366	Alpha amylase catalytic
BE24_RS13235	COG2188	Transcriptional regulator
BE24_RS13240	COG3153	acetyltransferase
BE24_RS13245	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BE24_RS13250	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
BE24_RS13255	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
BE24_RS13405	COG0085	RNA polymerase activity
BE24_RS13455	COG0739	heme binding
BE24_RS13465	COG2176	DNA-directed DNA polymerase activity
BE24_RS13470	COG0658	competence protein
BE24_RS13470	COG2333	competence protein COMEC
BE24_RS13485	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
BE24_RS13485	COG0463	Glycosyl transferase, family 2
BE24_RS13495	COG1401	restriction endodeoxyribonuclease activity
BE24_RS13515	COG1216	Glycosyl transferase, family 2
BE24_RS13515	COG1442	glycosyl transferase family 8