locus-tag	class	description
AWC37_RS00005	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AWC37_RS00010	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
AWC37_RS00015	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
AWC37_RS00020	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AWC37_RS00025	COG4463	regulation of RNA biosynthetic process
AWC37_RS00030	COG3880	PFAM UvrB UvrC protein
AWC37_RS00035	COG3869	Catalyzes the specific phosphorylation of arginine residues in
AWC37_RS00040	COG0542	response to heat
AWC37_RS00045	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
AWC37_RS00050	COG4956	integral membrane protein (PIN domain superfamily)
AWC37_RS00055	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AWC37_RS00060	COG1045	serine acetyltransferase
AWC37_RS00065	COG0215	cysteine-tRNA ligase activity
AWC37_RS00070	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
AWC37_RS00075	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AWC37_RS00100	COG0250	Participates in transcription elongation, termination and antitermination
AWC37_RS00105	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
AWC37_RS00110	COG0081	regulation of translation
AWC37_RS00115	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
AWC37_RS00125	COG2813	Specifically methylates the guanine in position
AWC37_RS00130	COG0085	RNA polymerase activity
AWC37_RS00135	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AWC37_RS00145	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
AWC37_RS00150	COG0049	tRNA binding
AWC37_RS00155	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AWC37_RS00160	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AWC37_RS00165	COG1473	amidohydrolase
AWC37_RS00260	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AWC37_RS00270	COG1316	TRANSCRIPTIONal
AWC37_RS00275	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
AWC37_RS00280	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AWC37_RS00285	COG1028	Short-chain dehydrogenase reductase Sdr
AWC37_RS00300	COG1686	Belongs to the peptidase S11 family
AWC37_RS00315	COG0667	Aldo Keto reductase
AWC37_RS00340	COG0583	DNA-binding transcription factor activity
AWC37_RS00355	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AWC37_RS00375	COG1904	glucuronate isomerase
AWC37_RS00380	COG1312	Catalyzes the dehydration of D-mannonate
AWC37_RS00385	COG1028	Short-chain dehydrogenase reductase Sdr
AWC37_RS00390	COG1132	(ABC) transporter
AWC37_RS00395	COG1349	DNA-binding transcription factor activity
AWC37_RS00400	COG2814	Major facilitator Superfamily
AWC37_RS00405	COG1063	alcohol dehydrogenase
AWC37_RS00410	COG1069	ribulokinase activity
AWC37_RS00425	COG1914	H( )-stimulated, divalent metal cation uptake system
AWC37_RS00430	COG0010	Belongs to the arginase family
AWC37_RS00440	COG0833	amino acid
AWC37_RS00445	COG2040	homocysteine
AWC37_RS00455	COG3239	Fatty acid desaturase
AWC37_RS00460	COG1113	amino acid transport
AWC37_RS00470	COG2824	Alkylphosphonate utilization operon protein PhnA
AWC37_RS00480	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AWC37_RS00500	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AWC37_RS00505	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
AWC37_RS00520	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AWC37_RS00540	COG0546	phosphoglycolate phosphatase activity
AWC37_RS00550	COG1428	Deoxynucleoside kinase
AWC37_RS00555	COG1428	Deoxynucleoside kinase
AWC37_RS00565	COG0561	phosphatase activity
AWC37_RS00570	COG0431	NADPH-dependent FMN reductase
AWC37_RS00585	COG1469	GTP cyclohydrolase I activity
AWC37_RS00590	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
AWC37_RS00600	COG0363	glucosamine-6-phosphate deaminase activity
AWC37_RS00605	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
AWC37_RS00610	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
AWC37_RS00615	COG3290	protein histidine kinase activity
AWC37_RS00620	COG4565	transcriptional regulatory protein
AWC37_RS00625	COG2832	Protein of unknown function (DUF454)
AWC37_RS00645	COG2329	Antibiotic biosynthesis monooxygenase
AWC37_RS00650	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AWC37_RS00660	COG0697	spore germination
AWC37_RS00670	COG1522	sequence-specific DNA binding
AWC37_RS00675	COG0384	phenazine biosynthesis protein PhzF
AWC37_RS00680	COG3493	citrate carrier protein
AWC37_RS00690	COG0318	PFAM AMP-dependent synthetase and ligase
AWC37_RS00695	COG0183	Belongs to the thiolase family
AWC37_RS00720	COG0351	phosphomethylpyrimidine kinase
AWC37_RS00725	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
AWC37_RS00735	COG2363	Small membrane protein
AWC37_RS00755	COG3253	May function as heme-dependent peroxidase
AWC37_RS00760	COG0280	phosphate acetyltransferase
AWC37_RS00765	COG0095	Lipoate-protein ligase
AWC37_RS00785	COG4844	belongs to the
AWC37_RS00790	COG0667	Aldo Keto reductase
AWC37_RS00795	COG0655	NAD(P)H dehydrogenase (quinone) activity
AWC37_RS00800	COG0456	acetyltransferase
AWC37_RS00805	COG1078	dGTPase activity
AWC37_RS00820	COG0018	arginyl-trna synthetase
AWC37_RS00830	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AWC37_RS00835	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AWC37_RS00840	COG0546	phosphoglycolate phosphatase activity
AWC37_RS00860	COG0596	Alpha beta hydrolase
AWC37_RS00900	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AWC37_RS00900	COG2111	Na H antiporter
AWC37_RS00905	COG2111	Na H antiporter
AWC37_RS00910	COG1006	Multisubunit Na H antiporter MnhC subunit
AWC37_RS00915	COG0651	ATP synthesis coupled electron transport
AWC37_RS00920	COG1863	multisubunit Na H antiporter MnhE subunit
AWC37_RS00925	COG2212	antiporter activity
AWC37_RS00930	COG1320	monovalent cation:proton antiporter activity
AWC37_RS00940	COG0803	Belongs to the bacterial solute-binding protein 9 family
AWC37_RS00945	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AWC37_RS00965	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
AWC37_RS00970	COG1134	teichoic acid transport
AWC37_RS00975	COG1682	transport, permease protein
AWC37_RS00980	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
AWC37_RS00990	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
AWC37_RS01000	COG1132	(ABC) transporter
AWC37_RS01005	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AWC37_RS01010	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AWC37_RS01015	COG1120	ATPase activity
AWC37_RS01020	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AWC37_RS01025	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AWC37_RS01030	COG2376	Dihydroxyacetone kinase
AWC37_RS01035	COG1461	Dihydroxyacetone kinase
AWC37_RS01040	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
AWC37_RS01050	COG3949	Membrane
AWC37_RS01055	COG0657	acetylesterase activity
AWC37_RS01065	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AWC37_RS01070	COG0745	RESPONSE REGULATOR receiver
AWC37_RS01075	COG2205	protein histidine kinase activity
AWC37_RS01080	COG1392	Phosphate transport regulator
AWC37_RS01085	COG0306	phosphate transporter
AWC37_RS01090	COG1388	LysM domain
AWC37_RS01090	COG3942	CHAP domain
AWC37_RS01110	COG0217	transcriptional regulatory protein
AWC37_RS01120	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
AWC37_RS01130	COG0583	DNA-binding transcription factor activity
AWC37_RS01135	COG2814	Major facilitator Superfamily
AWC37_RS01140	COG2839	Protein conserved in bacteria
AWC37_RS01145	COG2814	Major facilitator Superfamily
AWC37_RS01175	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AWC37_RS01180	COG1279	arginine transmembrane transporter activity
AWC37_RS01185	COG1611	Belongs to the LOG family
AWC37_RS01190	COG1671	Belongs to the UPF0178 family
AWC37_RS01200	COG1968	undecaprenyl-diphosphatase activity
AWC37_RS01205	COG4988	ABC transporter
AWC37_RS01210	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
AWC37_RS01225	COG4989	oxidoreductase activity
AWC37_RS01235	COG0586	Pfam SNARE associated Golgi protein
AWC37_RS01240	COG0039	L-malate dehydrogenase activity
AWC37_RS01270	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AWC37_RS01275	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AWC37_RS01280	COG1349	DNA-binding transcription factor activity
AWC37_RS01285	COG1105	Belongs to the carbohydrate kinase PfkB family
AWC37_RS01290	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AWC37_RS01290	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AWC37_RS01290	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AWC37_RS01295	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
AWC37_RS01300	COG1253	flavin adenine dinucleotide binding
AWC37_RS01305	COG0656	L-ascorbic acid biosynthetic process
AWC37_RS01310	COG0463	Glycosyl transferase, family 2
AWC37_RS01325	COG0602	queuosine metabolic process
AWC37_RS01330	COG0720	synthase
AWC37_RS01335	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
AWC37_RS01340	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AWC37_RS01340	COG0512	Glutamine amidotransferase of anthranilate synthase
AWC37_RS01345	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AWC37_RS01360	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
AWC37_RS01370	COG1368	sulfuric ester hydrolase activity
AWC37_RS01380	COG0488	(ABC) transporter
AWC37_RS01385	COG0514	ATP-dependent DNA helicase (RecQ)
AWC37_RS01395	COG1174	glycine betaine transport
AWC37_RS01400	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AWC37_RS01410	COG1597	lipid kinase activity
AWC37_RS01415	COG3104	oligopeptide transport
AWC37_RS01420	COG3104	oligopeptide transport
AWC37_RS01425	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
AWC37_RS01435	COG1780	Probably involved in ribonucleotide reductase function
AWC37_RS01440	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AWC37_RS01445	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AWC37_RS01450	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AWC37_RS01455	COG4605	iron ion homeostasis
AWC37_RS01460	COG4604	ABC transporter, ATP-binding protein
AWC37_RS01465	COG4607	ABC-type enterochelin transport system periplasmic component
AWC37_RS01480	COG0812	UDP-N-acetylmuramate dehydrogenase activity
AWC37_RS01500	COG1929	Belongs to the glycerate kinase type-1 family
AWC37_RS01505	COG2195	Cleaves the N-terminal amino acid of tripeptides
AWC37_RS01520	COG2199	diguanylate cyclase activity
AWC37_RS01525	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AWC37_RS01530	COG1739	Uncharacterized protein family UPF0029
AWC37_RS01540	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
AWC37_RS01545	COG1040	competence protein
AWC37_RS01550	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
AWC37_RS01555	COG0653	protein targeting
AWC37_RS01560	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
AWC37_RS01565	COG3942	CHAP domain
AWC37_RS01565	COG1388	LysM domain
AWC37_RS01580	COG0556	nucleotide-excision repair
AWC37_RS01590	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
AWC37_RS01595	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
AWC37_RS01600	COG0110	maltose O-acetyltransferase activity
AWC37_RS01610	COG0492	ferredoxin-NADP+ reductase activity
AWC37_RS01615	COG1660	Displays ATPase and GTPase activities
AWC37_RS01620	COG0391	Required for morphogenesis under gluconeogenic growth conditions
AWC37_RS01625	COG1481	regulation of sporulation
AWC37_RS01635	COG0740	serine-type endopeptidase activity
AWC37_RS01645	COG1090	epimerase
AWC37_RS01675	COG0126	phosphoglycerate kinase activity
AWC37_RS01680	COG0149	triose-phosphate isomerase activity
AWC37_RS01685	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
AWC37_RS01690	COG0148	phosphopyruvate hydratase activity
AWC37_RS01700	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AWC37_RS01705	COG1647	Serine aminopeptidase, S33
AWC37_RS01710	COG0557	exoribonuclease II activity
AWC37_RS01715	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
AWC37_RS01735	COG0667	Aldo Keto reductase
AWC37_RS01740	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AWC37_RS01770	COG0346	lactoylglutathione lyase activity
AWC37_RS01800	COG0346	lactoylglutathione lyase activity
AWC37_RS01820	COG0640	Transcriptional regulator
AWC37_RS01845	COG1073	alpha beta
AWC37_RS01860	COG0346	lactoylglutathione lyase activity
AWC37_RS01865	COG2153	protein acetylation
AWC37_RS01895	COG2314	TM2 domain
AWC37_RS01910	COG2851	Citrate transporter
AWC37_RS01925	COG1764	response to oxidative stress
AWC37_RS01930	COG0710	3-dehydroquinate dehydratase activity
AWC37_RS01935	COG0778	Nitroreductase
AWC37_RS01940	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AWC37_RS01945	COG1393	Belongs to the ArsC family
AWC37_RS01950	COG0509	glycine decarboxylation via glycine cleavage system
AWC37_RS01955	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
AWC37_RS01960	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AWC37_RS01965	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AWC37_RS01970	COG2011	ABC-type metal ion transport system permease component
AWC37_RS01975	COG1464	Belongs to the NlpA lipoprotein family
AWC37_RS01980	COG1253	flavin adenine dinucleotide binding
AWC37_RS01990	COG0396	ATPase activity
AWC37_RS01995	COG0719	Fe-S assembly protein
AWC37_RS02000	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AWC37_RS02005	COG0822	iron-sulfur transferase activity
AWC37_RS02010	COG0719	Fe-S assembly protein
AWC37_RS02015	COG3223	Belongs to the PsiE family
AWC37_RS02020	COG0454	-acetyltransferase
AWC37_RS02030	COG1253	flavin adenine dinucleotide binding
AWC37_RS02035	COG2070	2-Nitropropane dioxygenase
AWC37_RS02040	COG1801	Protein of unknown function DUF72
AWC37_RS02045	COG0730	response to heat
AWC37_RS02050	COG0737	Belongs to the 5'-nucleotidase family
AWC37_RS02055	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AWC37_RS02060	COG4470	Protein conserved in bacteria
AWC37_RS02070	COG2445	Protein of unknown function DUF86
AWC37_RS02075	COG0647	UMP catabolic process
AWC37_RS02080	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AWC37_RS02090	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AWC37_RS02095	COG1696	Membrane protein involved in D-alanine export
AWC37_RS02100	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AWC37_RS02105	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
AWC37_RS02110	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
AWC37_RS02115	COG4837	Protein of unknown function (DUF1462)
AWC37_RS02120	COG1252	NADH dehydrogenase
AWC37_RS02125	COG4844	belongs to the
AWC37_RS02130	COG0316	Belongs to the HesB IscA family
AWC37_RS02135	COG1252	NADH dehydrogenase
AWC37_RS02140	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AWC37_RS02145	COG2056	Na+-H+ antiporter family
AWC37_RS02150	COG2050	protein possibly involved in aromatic compounds catabolism
AWC37_RS02165	COG1320	monovalent cation:proton antiporter activity
AWC37_RS02170	COG2212	antiporter activity
AWC37_RS02175	COG1863	multisubunit Na H antiporter MnhE subunit
AWC37_RS02180	COG0651	ATP synthesis coupled electron transport
AWC37_RS02185	COG1006	Multisubunit Na H antiporter MnhC subunit
AWC37_RS02190	COG2111	Na H antiporter
AWC37_RS02195	COG2111	Na H antiporter
AWC37_RS02195	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AWC37_RS02205	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AWC37_RS02210	COG1098	S1 RNA binding domain
AWC37_RS02215	COG1902	pentaerythritol trinitrate reductase activity
AWC37_RS02220	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AWC37_RS02230	COG0584	glycerophosphoryl diester phosphodiesterase
AWC37_RS02235	COG0165	Argininosuccinate lyase
AWC37_RS02240	COG0137	argininosuccinate synthase activity
AWC37_RS02245	COG0166	Belongs to the GPI family
AWC37_RS02250	COG0398	Pfam SNARE associated Golgi protein
AWC37_RS02265	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
AWC37_RS02270	COG1074	ATP-dependent DNA helicase activity
AWC37_RS02275	COG2311	Membrane
AWC37_RS02280	COG0179	Fumarylacetoacetate (FAA) hydrolase
AWC37_RS02290	COG0446	pyridine nucleotide-disulphide oxidoreductase
AWC37_RS02295	COG0561	phosphatase activity
AWC37_RS02310	COG0542	response to heat
AWC37_RS02320	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AWC37_RS02340	COG0601	transmembrane transport
AWC37_RS02345	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AWC37_RS02350	COG0444	Belongs to the ABC transporter superfamily
AWC37_RS02355	COG4608	Belongs to the ABC transporter superfamily
AWC37_RS02360	COG4166	transmembrane transport
AWC37_RS02365	COG0180	Tryptophanyl-tRNA synthetase
AWC37_RS02370	COG1393	Belongs to the ArsC family
AWC37_RS02375	COG4862	establishment of competence for transformation
AWC37_RS02385	COG1164	Oligoendopeptidase f
AWC37_RS02390	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
AWC37_RS02395	COG2346	COG2346, Truncated hemoglobins
AWC37_RS02410	COG2357	RelA SpoT domain protein
AWC37_RS02415	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AWC37_RS02420	COG0564	pseudouridine synthase activity
AWC37_RS02425	COG2239	Acts as a magnesium transporter
AWC37_RS02430	COG0569	domain protein
AWC37_RS02430	COG0475	glutathione-regulated potassium exporter activity
AWC37_RS02440	COG0628	permease
AWC37_RS02445	COG1115	amino acid carrier protein
AWC37_RS02450	COG2382	esterase
AWC37_RS02455	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
AWC37_RS02460	COG2814	Major facilitator Superfamily
AWC37_RS02465	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AWC37_RS02470	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AWC37_RS02480	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
AWC37_RS02485	COG0861	Integral membrane protein TerC family
AWC37_RS02490	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AWC37_RS02495	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AWC37_RS02500	COG0737	Belongs to the 5'-nucleotidase family
AWC37_RS02510	COG4873	Protein conserved in bacteria
AWC37_RS02525	COG4903	ComK protein
AWC37_RS02545	COG2314	TM2 domain
AWC37_RS02555	COG1575	Belongs to the MenA family. Type 1 subfamily
AWC37_RS02560	COG1169	isochorismate synthase
AWC37_RS02565	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
AWC37_RS02570	COG2267	carboxylic ester hydrolase activity
AWC37_RS02575	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
AWC37_RS02580	COG1846	Transcriptional regulator
AWC37_RS02585	COG0436	Aminotransferase
AWC37_RS02590	COG3594	Acyltransferase
AWC37_RS02615	COG1316	TRANSCRIPTIONal
AWC37_RS02620	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AWC37_RS02635	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
AWC37_RS02640	COG1845	cytochrome c oxidase, subunit III
AWC37_RS02645	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AWC37_RS02650	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AWC37_RS02660	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AWC37_RS02660	COG1017	nitric oxide dioxygenase activity
AWC37_RS02665	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
AWC37_RS02670	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
AWC37_RS02675	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
AWC37_RS02680	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
AWC37_RS02685	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AWC37_RS02690	COG0047	phosphoribosylformylglycinamidine synthase activity
AWC37_RS02695	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AWC37_RS02705	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
AWC37_RS02715	COG0138	bifunctional purine biosynthesis protein purh
AWC37_RS02720	COG0151	Belongs to the GarS family
AWC37_RS02730	COG4172	Belongs to the ABC transporter superfamily
AWC37_RS02745	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
AWC37_RS02755	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AWC37_RS02760	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AWC37_RS02770	COG1271	oxidase subunit
AWC37_RS02775	COG1294	oxidase, subunit
AWC37_RS02780	COG0569	domain protein
AWC37_RS02785	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
AWC37_RS02790	COG5503	Protein of unknown function (DUF1447)
AWC37_RS02800	COG0242	peptide deformylase activity
AWC37_RS02830	COG4476	Belongs to the UPF0223 family
AWC37_RS02840	COG3842	ATPase activity
AWC37_RS02845	COG1176	ABC-type spermidine putrescine transport system, permease component I
AWC37_RS02850	COG1177	transmembrane transport
AWC37_RS02865	COG1914	H( )-stimulated, divalent metal cation uptake system
AWC37_RS02875	COG4493	Belongs to the UPF0637 family
AWC37_RS02880	COG0483	inositol monophosphate 1-phosphatase activity
AWC37_RS02890	COG1217	gtp-binding protein TYPA
AWC37_RS02895	COG4896	Protein conserved in bacteria
AWC37_RS02900	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
AWC37_RS02905	COG4838	Belongs to the UPF0358 family
AWC37_RS02910	COG0772	Belongs to the SEDS family
AWC37_RS02920	COG1612	heme a metabolic process
AWC37_RS02925	COG0109	protoheme IX farnesyltransferase activity
AWC37_RS02935	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AWC37_RS02945	COG3679	Belongs to the UPF0342 family
AWC37_RS02950	COG0584	glycerophosphoryl diester phosphodiesterase
AWC37_RS02955	COG4471	UPF0298 protein
AWC37_RS02965	COG0742	ribosomal rna small subunit methyltransferase
AWC37_RS02970	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
AWC37_RS02975	COG1323	Belongs to the UPF0348 family
AWC37_RS02985	COG0333	Belongs to the bacterial ribosomal protein bL32 family
AWC37_RS02995	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AWC37_RS03000	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
AWC37_RS03005	COG0072	phenylalanine-tRNA ligase activity
AWC37_RS03010	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AWC37_RS03015	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
AWC37_RS03025	COG1796	DNA polymerase
AWC37_RS03025	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
AWC37_RS03030	COG1193	negative regulation of DNA recombination
AWC37_RS03035	COG3118	belongs to the thioredoxin family
AWC37_RS03040	COG0322	excinuclease ABC activity
AWC37_RS03045	COG2009	succinate dehydrogenase
AWC37_RS03050	COG1053	succinate dehydrogenase
AWC37_RS03055	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AWC37_RS03060	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
AWC37_RS03065	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
AWC37_RS03080	COG0582	viral genome integration into host DNA
AWC37_RS03100	COG1525	nuclease
AWC37_RS03155	COG5377	YqaJ viral recombinase family
AWC37_RS03160	COG3723	Recombinational DNA repair protein, rece pathway
AWC37_RS03220	COG5484	DNA packaging
AWC37_RS03220	COG3728	DNA packaging
AWC37_RS03255	COG0052	Belongs to the universal ribosomal protein uS2 family
AWC37_RS03400	COG1011	Hydrolase
AWC37_RS03405	COG0454	-acetyltransferase
AWC37_RS03410	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
AWC37_RS03415	COG2001	Belongs to the MraZ family
AWC37_RS03420	COG0275	rRNA processing
AWC37_RS03425	COG4839	cell division protein FtsL
AWC37_RS03430	COG0768	penicillin binding
AWC37_RS03435	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AWC37_RS03440	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
AWC37_RS03450	COG0849	cell division
AWC37_RS03455	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AWC37_RS03460	COG1496	oxidoreductase activity
AWC37_RS03465	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
AWC37_RS03470	COG1799	cell septum assembly
AWC37_RS03475	COG0762	integral membrane protein
AWC37_RS03485	COG3599	regulation of cell shape
AWC37_RS03490	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
AWC37_RS03500	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
AWC37_RS03505	COG0564	pseudouridine synthase activity
AWC37_RS03510	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
AWC37_RS03520	COG0540	Belongs to the ATCase OTCase family
AWC37_RS03530	COG0505	Belongs to the CarA family
AWC37_RS03535	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
AWC37_RS03540	COG0284	orotidine-5'-phosphate decarboxylase activity
AWC37_RS03545	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
AWC37_RS03555	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AWC37_RS03565	COG1293	RNA-binding protein homologous to eukaryotic snRNP
AWC37_RS03570	COG0194	GDP metabolic process
AWC37_RS03575	COG1758	RNA polymerase activity
AWC37_RS03580	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AWC37_RS03585	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AWC37_RS03600	COG0242	peptide deformylase activity
AWC37_RS03605	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AWC37_RS03610	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AWC37_RS03610	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AWC37_RS03615	COG0820	rRNA (adenine-C2-)-methyltransferase activity
AWC37_RS03635	COG1162	GTPase activity
AWC37_RS03640	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AWC37_RS03645	COG1564	THIamine pyrophosphokinase
AWC37_RS03650	COG0227	Belongs to the bacterial ribosomal protein bL28 family
AWC37_RS03655	COG1302	Protein conserved in bacteria
AWC37_RS03660	COG1461	Dihydroxyacetone kinase
AWC37_RS03665	COG1760	l-serine dehydratase
AWC37_RS03670	COG1760	l-serine dehydratase
AWC37_RS03675	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AWC37_RS03685	COG1349	DNA-binding transcription factor activity
AWC37_RS03690	COG0416	fatty acid biosynthetic process
AWC37_RS03705	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AWC37_RS03710	COG0571	ribonuclease III activity
AWC37_RS03715	COG1196	nuclear chromosome segregation
AWC37_RS03720	COG0552	protein localization to endoplasmic reticulum
AWC37_RS03725	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
AWC37_RS03730	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AWC37_RS03735	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AWC37_RS03740	COG1028	Short-chain dehydrogenase reductase Sdr
AWC37_RS03745	COG0228	four-way junction DNA binding
AWC37_RS03750	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
AWC37_RS03755	COG0336	Belongs to the RNA methyltransferase TrmD family
AWC37_RS03760	COG0335	large ribosomal subunit rRNA binding
AWC37_RS03770	COG4485	Bacterial membrane protein, YfhO
AWC37_RS03780	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AWC37_RS03785	COG0045	succinate-CoA ligase (ADP-forming) activity
AWC37_RS03795	COG0758	DNA mediated transformation
AWC37_RS03800	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AWC37_RS03805	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
AWC37_RS03810	COG4974	Belongs to the 'phage' integrase family
AWC37_RS03815	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
AWC37_RS03820	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
AWC37_RS03825	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
AWC37_RS03830	COG0052	Belongs to the universal ribosomal protein uS2 family
AWC37_RS03835	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
AWC37_RS03840	COG0528	UMP kinase activity
AWC37_RS03845	COG0233	cytoplasmic translational termination
AWC37_RS03850	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AWC37_RS03855	COG4589	Belongs to the CDS family
AWC37_RS03865	COG0442	prolyl-tRNA aminoacylation
AWC37_RS03870	COG2176	DNA-directed DNA polymerase activity
AWC37_RS03875	COG0779	Required for maturation of 30S ribosomal subunits
AWC37_RS03880	COG0195	Participates in both transcription termination and antitermination
AWC37_RS03885	COG2740	Nucleic-acid-binding protein implicated in transcription termination
AWC37_RS03890	COG1358	cellular component organization or biogenesis
AWC37_RS03895	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
AWC37_RS03910	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
AWC37_RS03915	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AWC37_RS03920	COG0196	riboflavin kinase activity
AWC37_RS03925	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
AWC37_RS03930	COG1185	polyribonucleotide nucleotidyltransferase activity
AWC37_RS03935	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
AWC37_RS03940	COG1674	ftsk spoiiie
AWC37_RS03945	COG2188	Transcriptional regulator
AWC37_RS03950	COG0612	Peptidase, M16
AWC37_RS03955	COG0612	Peptidase, M16
AWC37_RS03960	COG0300	oxidoreductase activity
AWC37_RS03980	COG1546	Belongs to the CinA family
AWC37_RS03980	COG1058	Belongs to the CinA family
AWC37_RS03985	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
AWC37_RS03990	COG1418	mRNA catabolic process
AWC37_RS04000	COG1692	metallophosphoesterase
AWC37_RS04005	COG0674	pyruvate-flavodoxin oxidoreductase activity
AWC37_RS04005	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
AWC37_RS04010	COG1013	pyruvate-flavodoxin oxidoreductase activity
AWC37_RS04020	COG4195	phage-related replication protein
AWC37_RS04025	COG1959	2 iron, 2 sulfur cluster binding
AWC37_RS04040	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AWC37_RS04045	COG4550	Control of competence regulator ComK, YlbF/YmcA
AWC37_RS04055	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
AWC37_RS04060	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
AWC37_RS04075	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
AWC37_RS04080	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AWC37_RS04085	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
AWC37_RS04095	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
AWC37_RS04100	COG1923	regulation of RNA biosynthetic process
AWC37_RS04105	COG0386	Belongs to the glutathione peroxidase family
AWC37_RS04110	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AWC37_RS04115	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
AWC37_RS04120	COG0789	Transcriptional regulator
AWC37_RS04130	COG1764	response to oxidative stress
AWC37_RS04135	COG2808	Putative FMN-binding domain
AWC37_RS04170	COG0527	aspartate kinase activity
AWC37_RS04175	COG0460	homoserine dehydrogenase
AWC37_RS04180	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
AWC37_RS04185	COG0083	homoserine kinase activity
AWC37_RS04190	COG0561	phosphatase activity
AWC37_RS04200	COG0833	amino acid
AWC37_RS04205	COG0753	catalase activity
AWC37_RS04210	COG0267	Belongs to the bacterial ribosomal protein bL33 family
AWC37_RS04215	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
AWC37_RS04220	COG0516	GMP reductase activity
AWC37_RS04230	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AWC37_RS04250	COG3763	UPF0154 protein
AWC37_RS04255	COG0582	viral genome integration into host DNA
AWC37_RS04270	COG1396	sequence-specific DNA binding
AWC37_RS04290	COG5377	YqaJ viral recombinase family
AWC37_RS04295	COG3723	Recombinational DNA repair protein, rece pathway
AWC37_RS04315	COG1484	DNA-dependent DNA replication
AWC37_RS04380	COG0756	dUTP diphosphatase activity
AWC37_RS04430	COG3331	DNA recombination
AWC37_RS04520	COG0739	heme binding
AWC37_RS04585	COG4846	Membrane protein involved in cytochrome C biogenesis
AWC37_RS04590	COG0420	3'-5' exonuclease activity
AWC37_RS04595	COG0419	ATPase involved in DNA repair
AWC37_RS04600	COG1970	mechanosensitive ion channel activity
AWC37_RS04605	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AWC37_RS04610	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AWC37_RS04615	COG0824	Thioesterase
AWC37_RS04620	COG4841	protein insertion into membrane
AWC37_RS04625	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
AWC37_RS04635	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AWC37_RS04640	COG1115	amino acid carrier protein
AWC37_RS04645	COG3711	transcriptional antiterminator
AWC37_RS04655	COG0628	permease
AWC37_RS04660	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
AWC37_RS04660	COG0392	lysyltransferase activity
AWC37_RS04670	COG1609	Transcriptional regulator
AWC37_RS04675	COG1869	D-ribose catabolic process
AWC37_RS04680	COG1129	ABC transporter
AWC37_RS04685	COG1172	Belongs to the binding-protein-dependent transport system permease family
AWC37_RS04690	COG1879	ABC-type sugar transport system periplasmic component
AWC37_RS04705	COG1942	4-Oxalocrotonate Tautomerase
AWC37_RS04710	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AWC37_RS04715	COG0287	Prephenate dehydrogenase
AWC37_RS04725	COG1363	Peptidase, m42
AWC37_RS04780	COG0561	phosphatase activity
AWC37_RS04795	COG2801	Transposase and inactivated derivatives
AWC37_RS04805	COG0438	transferase activity, transferring glycosyl groups
AWC37_RS04820	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AWC37_RS04825	COG0512	Glutamine amidotransferase of anthranilate synthase
AWC37_RS04830	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AWC37_RS04835	COG0134	indole-3-glycerol-phosphate synthase activity
AWC37_RS04845	COG0133	tryptophan synthase activity
AWC37_RS04850	COG0159	tryptophan synthase activity
AWC37_RS04860	COG2348	transferase activity, transferring amino-acyl groups
AWC37_RS04875	COG4607	ABC-type enterochelin transport system periplasmic component
AWC37_RS04885	COG1164	Oligoendopeptidase f
AWC37_RS04890	COG0704	Plays a role in the regulation of phosphate uptake
AWC37_RS04895	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AWC37_RS04900	COG0581	inorganic phosphate transmembrane transporter activity
AWC37_RS04905	COG0573	inorganic phosphate transmembrane transporter activity
AWC37_RS04910	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AWC37_RS04915	COG2996	Protein conserved in bacteria
AWC37_RS04920	COG0488	(ABC) transporter
AWC37_RS04930	COG0527	aspartate kinase activity
AWC37_RS04935	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AWC37_RS04940	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AWC37_RS04945	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
AWC37_RS04955	COG1473	amidohydrolase
AWC37_RS04970	COG1278	Cold shock
AWC37_RS04980	COG1254	Belongs to the acylphosphatase family
AWC37_RS04990	COG3853	Toxic anion resistance protein (TelA)
AWC37_RS04995	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AWC37_RS05000	COG1114	Component of the transport system for branched-chain amino acids
AWC37_RS05005	COG4548	von Willebrand factor, type A
AWC37_RS05010	COG0714	Associated with various cellular activities
AWC37_RS05035	COG1121	(ABC) transporter
AWC37_RS05040	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
AWC37_RS05065	COG1917	Cupin 2, conserved barrel domain protein
AWC37_RS05065	COG2207	Transcriptional regulator
AWC37_RS05075	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
AWC37_RS05085	COG0508	dehydrogenase complex catalyzes the overall conversion of
AWC37_RS05090	COG0567	Dehydrogenase, E1 component
AWC37_RS05095	COG5002	protein histidine kinase activity
AWC37_RS05100	COG0745	RESPONSE REGULATOR receiver
AWC37_RS05105	COG0671	phosphoesterase, PA-phosphatase related
AWC37_RS05110	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AWC37_RS05120	COG0793	Belongs to the peptidase S41A family
AWC37_RS05125	COG4479	Belongs to the UPF0346 family
AWC37_RS05135	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AWC37_RS05155	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
AWC37_RS05165	COG1413	lyase activity
AWC37_RS05170	COG1413	lyase activity
AWC37_RS05180	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
AWC37_RS05185	COG3545	Serine hydrolase
AWC37_RS05195	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AWC37_RS05200	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
AWC37_RS05210	COG2962	Rard protein
AWC37_RS05215	COG0116	Belongs to the methyltransferase superfamily
AWC37_RS05230	COG4474	Belongs to the UPF0398 family
AWC37_RS05240	COG3331	DNA recombination
AWC37_RS05245	COG4499	WXG100 protein secretion system (Wss), protein YukC
AWC37_RS05245	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AWC37_RS05255	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AWC37_RS05260	COG3935	DnaD domain protein
AWC37_RS05265	COG0017	Asparaginyl-tRNA synthetase
AWC37_RS05270	COG1199	ATP-dependent helicase activity
AWC37_RS05270	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AWC37_RS05280	COG0617	tRNA 3'-terminal CCA addition
AWC37_RS05285	COG0438	transferase activity, transferring glycosyl groups
AWC37_RS05290	COG1694	Mazg nucleotide pyrophosphohydrolase
AWC37_RS05295	COG2738	Putative neutral zinc metallopeptidase
AWC37_RS05300	COG4347	Protein of unknown function (DUF1405)
AWC37_RS05305	COG5582	Belongs to the UPF0302 family
AWC37_RS05315	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
AWC37_RS05320	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
AWC37_RS05325	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
AWC37_RS05330	COG0105	UTP biosynthetic process
AWC37_RS05335	COG0142	geranyltranstransferase activity
AWC37_RS05340	COG2226	methyltransferase
AWC37_RS05355	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
AWC37_RS05360	COG1160	GTP binding
AWC37_RS05365	COG0539	negative regulation of cytoplasmic translation
AWC37_RS05370	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
AWC37_RS05380	COG0492	ferredoxin-NADP+ reductase activity
AWC37_RS05385	COG1388	LysM domain
AWC37_RS05390	COG0514	ATP-dependent DNA helicase (RecQ)
AWC37_RS05400	COG1141	Ferredoxin
AWC37_RS05415	COG0745	RESPONSE REGULATOR receiver
AWC37_RS05420	COG1187	pseudouridine synthase activity
AWC37_RS05425	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
AWC37_RS05430	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
AWC37_RS05440	COG4974	Belongs to the 'phage' integrase family
AWC37_RS05445	COG0735	belongs to the Fur family
AWC37_RS05450	COG0494	nUDIX hydrolase
AWC37_RS05455	COG0667	Aldo Keto reductase
AWC37_RS05465	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AWC37_RS05470	COG1234	tRNA 3'-trailer cleavage
AWC37_RS05475	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
AWC37_RS05485	COG0366	Alpha amylase catalytic
AWC37_RS05490	COG1609	Transcriptional regulator
AWC37_RS05500	COG2195	Cleaves the N-terminal amino acid of tripeptides
AWC37_RS05505	COG4129	membrane
AWC37_RS05515	COG0508	dehydrogenase complex catalyzes the overall conversion of
AWC37_RS05520	COG0022	dehydrogenase e1 component
AWC37_RS05525	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AWC37_RS05530	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AWC37_RS05535	COG3426	butyrate kinase activity
AWC37_RS05540	COG0280	phosphate acetyltransferase
AWC37_RS05545	COG0497	DNA recombination
AWC37_RS05550	COG1438	arginine binding
AWC37_RS05560	COG1722	exodeoxyribonuclease VII activity
AWC37_RS05565	COG1570	exodeoxyribonuclease VII activity
AWC37_RS05570	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AWC37_RS05575	COG1302	Protein conserved in bacteria
AWC37_RS05580	COG0439	Biotin carboxylase
AWC37_RS05585	COG0511	ligase activity, forming carbon-carbon bonds
AWC37_RS05590	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AWC37_RS05595	COG0006	proline dipeptidase activity
AWC37_RS05610	COG0095	Lipoate-protein ligase
AWC37_RS05615	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AWC37_RS05620	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AWC37_RS05625	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AWC37_RS05630	COG0404	The glycine cleavage system catalyzes the degradation of glycine
AWC37_RS05635	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AWC37_RS05670	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AWC37_RS05675	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AWC37_RS05680	COG0011	TIGRFAM Protein of
AWC37_RS05685	COG1940	carbohydrate kinase activity
AWC37_RS05690	COG4483	Protein conserved in bacteria
AWC37_RS05695	COG0705	Rhomboid family
AWC37_RS05695	COG0457	Tetratricopeptide repeat
AWC37_RS05700	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AWC37_RS05705	COG0267	Belongs to the bacterial ribosomal protein bL33 family
AWC37_RS05710	COG0768	penicillin binding
AWC37_RS05715	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AWC37_RS05725	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AWC37_RS05730	COG1121	(ABC) transporter
AWC37_RS05735	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
AWC37_RS05740	COG0513	Belongs to the DEAD box helicase family
AWC37_RS05750	COG2384	SAM-dependent methyltransferase
AWC37_RS05755	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AWC37_RS05765	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
AWC37_RS05770	COG0517	IMP dehydrogenase activity
AWC37_RS05775	COG0423	glycine-tRNA ligase activity
AWC37_RS05780	COG1381	Involved in DNA repair and RecF pathway recombination
AWC37_RS05785	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
AWC37_RS05790	COG0295	cytidine deaminase activity
AWC37_RS05795	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
AWC37_RS05800	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
AWC37_RS05805	COG1702	phosphate starvation-inducible protein PhoH
AWC37_RS05815	COG4864	UPF0365 protein
AWC37_RS05820	COG1030	water channel activity
AWC37_RS05825	COG0828	Belongs to the bacterial ribosomal protein bS21 family
AWC37_RS05830	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AWC37_RS05835	COG2264	protein methyltransferase activity
AWC37_RS05840	COG0484	heat shock protein binding
AWC37_RS05845	COG0443	Heat shock 70 kDa protein
AWC37_RS05850	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AWC37_RS05855	COG1420	regulation of RNA biosynthetic process
AWC37_RS05860	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AWC37_RS05865	COG0481	GTPase activity
AWC37_RS05870	COG0268	Binds directly to 16S ribosomal RNA
AWC37_RS05875	COG1466	dna polymerase III delta subunit
AWC37_RS05880	COG0658	competence protein
AWC37_RS05880	COG2333	competence protein COMEC
AWC37_RS05885	COG2131	deaminase
AWC37_RS05890	COG1596	polysaccharide export
AWC37_RS05890	COG1555	photosystem II stabilization
AWC37_RS05895	COG2226	methyltransferase
AWC37_RS05900	COG0799	negative regulation of ribosome biogenesis
AWC37_RS05905	COG1713	HD superfamily hydrolase involved in NAD metabolism
AWC37_RS05910	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
AWC37_RS05915	COG1534	Rna-binding protein
AWC37_RS05920	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AWC37_RS05925	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
AWC37_RS05930	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
AWC37_RS05935	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AWC37_RS05940	COG0730	response to heat
AWC37_RS05945	COG1914	H( )-stimulated, divalent metal cation uptake system
AWC37_RS05950	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
AWC37_RS05955	COG0439	Biotin carboxylase
AWC37_RS05960	COG0511	ligase activity, forming carbon-carbon bonds
AWC37_RS05965	COG1984	allophanate hydrolase subunit 2
AWC37_RS05970	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
AWC37_RS05975	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AWC37_RS05980	COG0572	uridine kinase
AWC37_RS05985	COG0826	peptidase U32
AWC37_RS05990	COG0826	peptidase U32
AWC37_RS05995	COG4122	O-methyltransferase activity
AWC37_RS06000	COG3906	Belongs to the UPF0473 family
AWC37_RS06005	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
AWC37_RS06010	COG4472	Bacterial protein of unknown function (DUF965)
AWC37_RS06015	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AWC37_RS06020	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AWC37_RS06030	COG0482	sulfurtransferase activity
AWC37_RS06035	COG1104	cysteine desulfurase activity
AWC37_RS06040	COG0488	(ABC) transporter
AWC37_RS06045	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AWC37_RS06055	COG1959	2 iron, 2 sulfur cluster binding
AWC37_RS06060	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AWC37_RS06065	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
AWC37_RS06075	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
AWC37_RS06080	COG0124	histidyl-tRNA synthetase
AWC37_RS06085	COG0860	N-Acetylmuramoyl-L-alanine amidase
AWC37_RS06090	COG1490	D-aminoacyl-tRNA deacylase activity
AWC37_RS06095	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AWC37_RS06105	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
AWC37_RS06105	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
AWC37_RS06110	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AWC37_RS06110	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AWC37_RS06115	COG1862	Preprotein translocase
AWC37_RS06120	COG0343	queuine tRNA-ribosyltransferase activity
AWC37_RS06125	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
AWC37_RS06130	COG2255	four-way junction helicase activity
AWC37_RS06135	COG0632	four-way junction helicase activity
AWC37_RS06140	COG4492	Belongs to the UPF0735 family
AWC37_RS06145	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AWC37_RS06150	COG0211	Belongs to the bacterial ribosomal protein bL27 family
AWC37_RS06155	COG2868	ribosomal protein
AWC37_RS06160	COG0261	This protein binds to 23S rRNA in the presence of protein L20
AWC37_RS06185	COG2003	Belongs to the UPF0758 family
AWC37_RS06200	COG0285	dihydrofolate synthase activity
AWC37_RS06205	COG0525	valine-tRNA ligase activity
AWC37_RS06210	COG2818	Glycosylase
AWC37_RS06220	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
AWC37_RS06225	COG0113	porphobilinogen synthase activity
AWC37_RS06235	COG0181	hydroxymethylbilane synthase activity
AWC37_RS06240	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AWC37_RS06245	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
AWC37_RS06250	COG0218	Necessary for normal cell division and for the maintenance of normal septation
AWC37_RS06255	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
AWC37_RS06260	COG0544	peptidyl-prolyl cis-trans isomerase activity
AWC37_RS06270	COG4112	unkown
AWC37_RS06275	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
AWC37_RS06280	COG0291	Belongs to the bacterial ribosomal protein bL35 family
AWC37_RS06285	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
AWC37_RS06290	COG0833	amino acid
AWC37_RS06295	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AWC37_RS06300	COG1484	DNA-dependent DNA replication
AWC37_RS06310	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
AWC37_RS06315	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AWC37_RS06320	COG0237	dephospho-CoA kinase activity
AWC37_RS06330	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AWC37_RS06330	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AWC37_RS06335	COG5002	protein histidine kinase activity
AWC37_RS06340	COG0745	RESPONSE REGULATOR receiver
AWC37_RS06345	COG0538	isocitrate dehydrogenase activity
AWC37_RS06350	COG0372	Belongs to the citrate synthase family
AWC37_RS06355	COG1113	amino acid transport
AWC37_RS06360	COG0469	pyruvate kinase activity
AWC37_RS06365	COG0205	6-phosphofructokinase activity
AWC37_RS06370	COG0825	malonyl-CoA metabolic process
AWC37_RS06375	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
AWC37_RS06380	COG0281	malic enzyme
AWC37_RS06385	COG0587	DNA-directed DNA polymerase activity
AWC37_RS06390	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
AWC37_RS06395	COG4109	DRTGG domain
AWC37_RS06405	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
AWC37_RS06410	COG0006	proline dipeptidase activity
AWC37_RS06415	COG3142	Participates in the control of copper homeostasis
AWC37_RS06420	COG0686	Belongs to the AlaDH PNT family
AWC37_RS06425	COG0589	response to stress
AWC37_RS06435	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AWC37_RS06440	COG0827	DNA restriction-modification system
AWC37_RS06445	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
AWC37_RS06450	COG1714	RDD family
AWC37_RS06455	COG0616	signal peptide processing
AWC37_RS06465	COG0301	tRNA thio-modification
AWC37_RS06470	COG1104	cysteine desulfurase activity
AWC37_RS06475	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
AWC37_RS06480	COG1956	GAF domain-containing protein
AWC37_RS06485	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
AWC37_RS06490	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AWC37_RS06495	COG0584	glycerophosphoryl diester phosphodiesterase
AWC37_RS06500	COG1764	response to oxidative stress
AWC37_RS06505	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
AWC37_RS06510	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AWC37_RS06520	COG1263	PTS System
AWC37_RS06520	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AWC37_RS06525	COG0204	Acyl-transferase
AWC37_RS06530	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AWC37_RS06535	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AWC37_RS06550	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AWC37_RS06555	COG0454	-acetyltransferase
AWC37_RS06560	COG0123	including yeast histone deacetylase and acetoin utilization protein
AWC37_RS06570	COG1609	Transcriptional regulator
AWC37_RS06575	COG1605	Chorismate mutase
AWC37_RS06575	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
AWC37_RS06585	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
AWC37_RS06590	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AWC37_RS06595	COG1674	ftsk spoiiie
AWC37_RS06600	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AWC37_RS06605	COG4848	Belongs to the UPF0354 family
AWC37_RS06610	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AWC37_RS06615	COG1363	Peptidase, m42
AWC37_RS06625	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AWC37_RS06630	COG0220	tRNA (guanine-N7-)-methyltransferase activity
AWC37_RS06635	COG0510	thiamine kinase activity
AWC37_RS06640	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AWC37_RS06645	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AWC37_RS06655	COG1187	pseudouridine synthase activity
AWC37_RS06660	COG2244	polysaccharide biosynthetic process
AWC37_RS06665	COG2081	HI0933 family
AWC37_RS06675	COG0495	leucyl-tRNA aminoacylation
AWC37_RS06680	COG2814	Major facilitator Superfamily
AWC37_RS06685	COG1242	4 iron, 4 sulfur cluster binding
AWC37_RS06690	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
AWC37_RS06700	COG0039	L-malate dehydrogenase activity
AWC37_RS06705	COG2267	carboxylic ester hydrolase activity
AWC37_RS06715	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
AWC37_RS06720	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AWC37_RS06720	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AWC37_RS06725	COG0307	riboflavin synthase, alpha
AWC37_RS06730	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AWC37_RS06730	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AWC37_RS06745	COG3266	domain, Protein
AWC37_RS06745	COG4193	domain, Protein
AWC37_RS06745	COG5632	N-Acetylmuramoyl-L-alanine amidase
AWC37_RS06755	COG1595	DNA-templated transcription, initiation
AWC37_RS06775	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AWC37_RS06785	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AWC37_RS06790	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AWC37_RS06795	COG0656	L-ascorbic acid biosynthetic process
AWC37_RS06805	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
AWC37_RS06810	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
AWC37_RS06815	COG1506	peptidase
AWC37_RS06825	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
AWC37_RS06835	COG0318	PFAM AMP-dependent synthetase and ligase
AWC37_RS06865	COG0300	oxidoreductase activity
AWC37_RS06945	COG3545	Serine hydrolase
AWC37_RS06950	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
AWC37_RS06955	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
AWC37_RS06960	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
AWC37_RS06970	COG4473	ABC transporter
AWC37_RS06975	COG1131	(ABC) transporter
AWC37_RS06980	COG0537	adenosine 5'-monophosphoramidase activity
AWC37_RS06995	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AWC37_RS07000	COG3481	metal-dependent phosphohydrolase, HD sub domain
AWC37_RS07005	COG4717	serine-type aminopeptidase activity
AWC37_RS07010	COG0420	3'-5' exonuclease activity
AWC37_RS07015	COG3679	Belongs to the UPF0342 family
AWC37_RS07020	COG4399	Belongs to the UPF0754 family
AWC37_RS07030	COG0788	formyltetrahydrofolate deformylase activity
AWC37_RS07045	COG1682	transport, permease protein
AWC37_RS07055	COG0730	response to heat
AWC37_RS07060	COG1316	TRANSCRIPTIONal
AWC37_RS07065	COG0772	Belongs to the SEDS family
AWC37_RS07070	COG1301	dicarboxylic acid transport
AWC37_RS07075	COG2197	response regulator
AWC37_RS07080	COG4585	Histidine kinase
AWC37_RS07080	COG2203	Gaf domain
AWC37_RS07085	COG0564	pseudouridine synthase activity
AWC37_RS07090	COG0114	fumarate hydratase activity
AWC37_RS07105	COG0363	glucosamine-6-phosphate deaminase activity
AWC37_RS07115	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AWC37_RS07120	COG1126	abc transporter atp-binding protein
AWC37_RS07125	COG0765	amino acid transport
AWC37_RS07140	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
AWC37_RS07280	COG0735	belongs to the Fur family
AWC37_RS07285	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AWC37_RS07290	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AWC37_RS07295	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
AWC37_RS07300	COG4129	membrane
AWC37_RS07310	COG3557	Belongs to the UPF0374 family
AWC37_RS07320	COG1988	membrane-bound metal-dependent
AWC37_RS07330	COG1134	teichoic acid transport
AWC37_RS07340	COG2137	regulation of response to DNA damage stimulus
AWC37_RS07345	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AWC37_RS07350	COG0693	protein deglycase activity
AWC37_RS07360	COG0535	radical SAM domain protein
AWC37_RS07365	COG1607	acyl-coa hydrolase
AWC37_RS07370	COG2309	aminopeptidase activity
AWC37_RS07375	COG4840	Belongs to the UPF0435 family
AWC37_RS07380	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AWC37_RS07390	COG1295	ribonuclease BN
AWC37_RS07395	COG2197	response regulator
AWC37_RS07400	COG4585	Histidine kinase
AWC37_RS07415	COG0024	Methionine aminopeptidase
AWC37_RS07420	COG4129	membrane
AWC37_RS07435	COG1528	Iron-storage protein
AWC37_RS07445	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AWC37_RS07455	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AWC37_RS07460	COG1597	lipid kinase activity
AWC37_RS07465	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AWC37_RS07470	COG0154	amidase activity
AWC37_RS07475	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AWC37_RS07480	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AWC37_RS07485	COG4851	CamS sex pheromone cAM373 precursor
AWC37_RS07490	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AWC37_RS07500	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
AWC37_RS07505	COG1876	peptidase activity
AWC37_RS07510	COG4496	protein, YerC YecD
AWC37_RS07515	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AWC37_RS07525	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
AWC37_RS07530	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
AWC37_RS07535	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
AWC37_RS07545	COG0077	Prephenate dehydratase
AWC37_RS07550	COG0471	metal ion transport
AWC37_RS07560	COG1335	isochorismatase
AWC37_RS07565	COG1227	inorganic diphosphatase activity
AWC37_RS07570	COG1012	belongs to the aldehyde dehydrogenase family
AWC37_RS07575	COG2706	6-phosphogluconolactonase activity
AWC37_RS07615	COG1131	(ABC) transporter
AWC37_RS07630	COG1725	Transcriptional regulator
AWC37_RS07650	COG0459	protein refolding
AWC37_RS07655	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
AWC37_RS07675	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AWC37_RS07680	COG4512	PFAM Accessory gene regulator B
AWC37_RS07690	COG3290	protein histidine kinase activity
AWC37_RS07695	COG3279	Response regulator of the LytR AlgR family
AWC37_RS07700	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AWC37_RS07705	COG1621	beta-fructofuranosidase activity
AWC37_RS07710	COG1609	Transcriptional regulator
AWC37_RS07715	COG0425	Belongs to the sulfur carrier protein TusA family
AWC37_RS07720	COG2391	methyltransferase activity
AWC37_RS07725	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
AWC37_RS07730	COG0488	(ABC) transporter
AWC37_RS07740	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
AWC37_RS07750	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
AWC37_RS07755	COG0456	acetyltransferase
AWC37_RS07760	COG1214	PFAM Peptidase M22, glycoprotease
AWC37_RS07765	COG0802	atpase or kinase
AWC37_RS07770	COG0129	dihydroxy-acid dehydratase activity
AWC37_RS07775	COG0028	Belongs to the TPP enzyme family
AWC37_RS07780	COG0440	acetolactate synthase activity
AWC37_RS07785	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
AWC37_RS07790	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AWC37_RS07795	COG0473	3-isopropylmalate dehydrogenase activity
AWC37_RS07800	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
AWC37_RS07805	COG0066	3-isopropylmalate dehydratase activity
AWC37_RS07810	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AWC37_RS07840	COG3091	SprT-like family
AWC37_RS07845	COG2183	response to ionizing radiation
AWC37_RS07850	COG1191	sigma factor activity
AWC37_RS07865	COG2208	phosphoserine phosphatase activity
AWC37_RS07870	COG2337	Toxic component of a toxin-antitoxin (TA) module
AWC37_RS07880	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AWC37_RS07895	COG3428	Bacterial PH domain
AWC37_RS07905	COG0513	Belongs to the DEAD box helicase family
AWC37_RS07910	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AWC37_RS07915	COG1181	Belongs to the D-alanine--D-alanine ligase family
AWC37_RS07920	COG0772	Belongs to the SEDS family
AWC37_RS07930	COG1937	Protein conserved in bacteria
AWC37_RS07940	COG1418	mRNA catabolic process
AWC37_RS07945	COG0706	membrane insertase activity
AWC37_RS07950	COG0352	thiamine-phosphate diphosphorylase activity
AWC37_RS07955	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
AWC37_RS07965	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
AWC37_RS07970	COG1388	LysM domain
AWC37_RS07975	COG0629	single-stranded DNA binding
AWC37_RS07985	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AWC37_RS07990	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AWC37_RS08000	COG0355	proton-transporting ATP synthase activity, rotational mechanism
AWC37_RS08005	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
AWC37_RS08010	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
AWC37_RS08015	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
AWC37_RS08020	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AWC37_RS08025	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AWC37_RS08030	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AWC37_RS08035	COG0356	it plays a direct role in the translocation of protons across the membrane
AWC37_RS08045	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
AWC37_RS08050	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
AWC37_RS08055	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AWC37_RS08060	COG4475	Protein of unknown function (DUF436)
AWC37_RS08065	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AWC37_RS08070	COG0009	L-threonylcarbamoyladenylate synthase
AWC37_RS08075	COG2890	protein-(glutamine-N5) methyltransferase activity
AWC37_RS08080	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
AWC37_RS08085	COG1435	thymidine kinase activity
AWC37_RS08090	COG0254	rRNA binding
AWC37_RS08095	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
AWC37_RS08100	COG1012	belongs to the aldehyde dehydrogenase family
AWC37_RS08110	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AWC37_RS08115	COG0191	fructose-bisphosphate aldolase activity
AWC37_RS08120	COG0504	CTP synthase activity
AWC37_RS08130	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AWC37_RS08135	COG5146	pantothenate kinase activity
AWC37_RS08155	COG1854	S-ribosylhomocysteine lyase activity
AWC37_RS08165	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
AWC37_RS08170	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
AWC37_RS08175	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
AWC37_RS08180	COG0813	purine-nucleoside phosphorylase activity
AWC37_RS08185	COG0783	Belongs to the Dps family
AWC37_RS08190	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AWC37_RS08205	COG2855	membrane
AWC37_RS08215	COG1482	cell wall glycoprotein biosynthetic process
AWC37_RS08220	COG2186	Transcriptional regulator
AWC37_RS08225	COG0702	epimerase
AWC37_RS08230	COG0640	Transcriptional regulator
AWC37_RS08255	COG1119	ATPase activity
AWC37_RS08270	COG2213	PTS system mannitol-specific
AWC37_RS08275	COG3711	transcriptional antiterminator
AWC37_RS08285	COG0246	Mannitol dehydrogenase
AWC37_RS08290	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AWC37_RS08300	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
AWC37_RS08355	COG0489	protein tyrosine kinase activity
AWC37_RS08370	COG1272	protein, Hemolysin III
AWC37_RS08375	COG4284	Utp--glucose-1-phosphate uridylyltransferase
AWC37_RS08380	COG1988	membrane-bound metal-dependent
AWC37_RS08390	COG2329	Antibiotic biosynthesis monooxygenase
AWC37_RS08395	COG3314	Sporulation integral membrane protein YlbJ
AWC37_RS08400	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AWC37_RS08405	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AWC37_RS08410	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
AWC37_RS08415	COG3457	Alanine racemase
AWC37_RS08420	COG4264	IucA IucC family
AWC37_RS08425	COG2814	Major facilitator Superfamily
AWC37_RS08430	COG4264	IucA IucC family
AWC37_RS08435	COG1302	Protein conserved in bacteria
AWC37_RS08450	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AWC37_RS08455	COG0604	alcohol dehydrogenase
AWC37_RS08460	COG2130	NADP-dependent
AWC37_RS08465	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AWC37_RS08475	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
AWC37_RS08480	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
AWC37_RS08485	COG0101	tRNA pseudouridine synthase activity
AWC37_RS08495	COG1122	ATPase activity
AWC37_RS08500	COG1122	ATPase activity
AWC37_RS08505	COG0203	ribosomal protein L17
AWC37_RS08510	COG0202	RNA polymerase activity
AWC37_RS08515	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
AWC37_RS08520	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
AWC37_RS08525	COG0257	Belongs to the bacterial ribosomal protein bL36 family
AWC37_RS08540	COG0201	protein transport
AWC37_RS08545	COG0200	Binds to the 23S rRNA
AWC37_RS08550	COG1841	ribosomal large subunit assembly
AWC37_RS08555	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
AWC37_RS08560	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
AWC37_RS08565	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
AWC37_RS08570	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
AWC37_RS08575	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
AWC37_RS08580	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
AWC37_RS08585	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
AWC37_RS08590	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
AWC37_RS08595	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
AWC37_RS08600	COG0255	Belongs to the universal ribosomal protein uL29 family
AWC37_RS08605	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
AWC37_RS08610	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
AWC37_RS08615	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
AWC37_RS08620	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AWC37_RS08625	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AWC37_RS08630	COG0089	rRNA binding
AWC37_RS08635	COG0088	Forms part of the polypeptide exit tunnel
AWC37_RS08640	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
AWC37_RS08645	COG0051	transcription antitermination factor activity, RNA binding
AWC37_RS08655	COG2252	PERMEase
AWC37_RS08660	COG0551	DNA topoisomerase type I activity
AWC37_RS08660	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AWC37_RS08670	COG4975	Glucose uptake
AWC37_RS08690	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AWC37_RS08695	COG2348	transferase activity, transferring amino-acyl groups
AWC37_RS08725	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AWC37_RS08730	COG0746	molybdenum cofactor guanylyltransferase activity
AWC37_RS08755	COG0315	cyclic pyranopterin monophosphate synthase activity
AWC37_RS08760	COG0521	Mo-molybdopterin cofactor biosynthetic process
AWC37_RS08765	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AWC37_RS08770	COG1510	regulation of RNA biosynthetic process
AWC37_RS08775	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
AWC37_RS08780	COG4149	molybdate abc transporter
AWC37_RS08785	COG0725	ABC transporter, periplasmic molybdate-binding protein
AWC37_RS08790	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
AWC37_RS08795	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AWC37_RS08800	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
AWC37_RS08805	COG1609	Transcriptional regulator
AWC37_RS08810	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
AWC37_RS08820	COG1268	BioY protein
AWC37_RS08825	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AWC37_RS08830	COG1960	acyl-CoA dehydrogenase activity
AWC37_RS08835	COG1126	abc transporter atp-binding protein
AWC37_RS08840	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AWC37_RS08845	COG0765	amino acid transport
AWC37_RS08850	COG0765	amino acid transport
AWC37_RS08875	COG3942	CHAP domain
AWC37_RS08880	COG1757	Na H antiporter
AWC37_RS08895	COG3942	CHAP domain
AWC37_RS08900	COG2076	Multidrug Resistance protein
AWC37_RS08905	COG2076	Multidrug Resistance protein
AWC37_RS08910	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AWC37_RS08935	COG3383	formate dehydrogenase (NAD+) activity
AWC37_RS08940	COG1316	TRANSCRIPTIONal
AWC37_RS08965	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
AWC37_RS08970	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AWC37_RS08970	COG1263	PTS System
AWC37_RS08980	COG1785	Belongs to the alkaline phosphatase family
AWC37_RS08985	COG1113	amino acid transport
AWC37_RS09010	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AWC37_RS09015	COG0385	Bile acid
AWC37_RS09025	COG1263	PTS System
AWC37_RS09025	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AWC37_RS09045	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AWC37_RS09050	COG1028	Short-chain dehydrogenase reductase Sdr
AWC37_RS09055	COG1473	amidohydrolase
AWC37_RS09060	COG0659	secondary active sulfate transmembrane transporter activity
AWC37_RS09065	COG1228	amidohydrolase
AWC37_RS09070	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
AWC37_RS09075	COG3314	Sporulation integral membrane protein YlbJ
AWC37_RS09080	COG0583	DNA-binding transcription factor activity
AWC37_RS09085	COG0010	Belongs to the arginase family
AWC37_RS09090	COG1266	CAAX protease self-immunity
AWC37_RS09095	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
AWC37_RS09100	COG2258	MOSC domain
AWC37_RS09105	COG2017	converts alpha-aldose to the beta-anomer
AWC37_RS09110	COG1668	transmembrane transport
AWC37_RS09115	COG4152	abc transporter atp-binding protein
AWC37_RS09120	COG1069	ribulokinase activity
AWC37_RS09125	COG3152	Membrane
AWC37_RS09130	COG2094	Belongs to the DNA glycosylase MPG family
AWC37_RS09135	COG1757	Na H antiporter
AWC37_RS09140	COG0786	glutamate:sodium symporter activity
AWC37_RS09145	COG1304	FMN binding
AWC37_RS09150	COG0598	Magnesium transport protein CorA
AWC37_RS09175	COG2814	Major facilitator Superfamily
AWC37_RS09180	COG1566	PFAM secretion protein HlyD family protein
AWC37_RS09190	COG2814	Major facilitator Superfamily
AWC37_RS09195	COG4640	response to antibiotic
AWC37_RS09210	COG1136	(ABC) transporter
AWC37_RS09215	COG0577	efflux transmembrane transporter activity
AWC37_RS09220	COG0745	RESPONSE REGULATOR receiver
AWC37_RS09225	COG5002	protein histidine kinase activity
AWC37_RS09225	COG3850	Histidine kinase
AWC37_RS09235	COG0438	transferase activity, transferring glycosyl groups
AWC37_RS09240	COG1620	l-lactate permease
AWC37_RS09260	COG0604	alcohol dehydrogenase
AWC37_RS09265	COG2814	Major facilitator Superfamily
AWC37_RS09275	COG0492	ferredoxin-NADP+ reductase activity
AWC37_RS09285	COG0698	ribose 5-phosphate isomerase
AWC37_RS09295	COG2376	Dihydroxyacetone kinase
AWC37_RS09300	COG1063	alcohol dehydrogenase
AWC37_RS09305	COG1349	DNA-binding transcription factor activity
AWC37_RS09310	COG1288	antiporter activity
AWC37_RS09315	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AWC37_RS09320	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AWC37_RS09325	COG1028	Short-chain dehydrogenase reductase Sdr
AWC37_RS09330	COG1283	sodium-dependent phosphate transmembrane transporter activity
AWC37_RS09350	COG1263	PTS System
AWC37_RS09350	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AWC37_RS09375	COG1846	Transcriptional regulator
AWC37_RS09390	COG2223	nitrite transmembrane transporter activity
AWC37_RS09400	COG4585	Histidine kinase
AWC37_RS09410	COG2181	nitrate reductase activity
AWC37_RS09420	COG1140	nitrate reductase beta subunit
AWC37_RS09425	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
AWC37_RS09445	COG2146	nitrite reductase [NAD(P)H] activity
AWC37_RS09450	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AWC37_RS09465	COG0454	-acetyltransferase
AWC37_RS09470	COG2116	formate transmembrane transporter activity
AWC37_RS09475	COG2188	Transcriptional regulator
AWC37_RS09480	COG1263	PTS System
AWC37_RS09480	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AWC37_RS09480	COG2190	(PTS) system
AWC37_RS09485	COG2723	6-phospho-beta-galactosidase activity
AWC37_RS09500	COG1695	Transcriptional regulator
AWC37_RS09510	COG2353	YceI-like domain
AWC37_RS09515	COG0803	Belongs to the bacterial solute-binding protein 9 family
AWC37_RS09515	COG3443	Belongs to the bacterial solute-binding protein 9 family
AWC37_RS09520	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AWC37_RS09535	COG2814	Major facilitator Superfamily
AWC37_RS09540	COG0588	phosphoglycerate mutase activity
AWC37_RS09545	COG1388	LysM domain
AWC37_RS09550	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
AWC37_RS09560	COG2814	Major facilitator Superfamily
AWC37_RS09580	COG0025	NhaP-type Na H and K H
AWC37_RS09585	COG0706	membrane insertase activity
AWC37_RS09595	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
AWC37_RS09615	COG4187	Peptidase family M20/M25/M40
AWC37_RS09625	COG3275	phosphorelay sensor kinase activity
AWC37_RS09630	COG3279	Response regulator of the LytR AlgR family
AWC37_RS09635	COG1380	Effector of murein hydrolase LrgA
AWC37_RS09640	COG1346	cytolysis
AWC37_RS09650	COG1174	glycine betaine transport
AWC37_RS09660	COG1174	glycine betaine transport
AWC37_RS09675	COG1250	3-hydroxyacyl-CoA dehydrogenase
AWC37_RS09680	COG3246	L-lysine catabolic process to acetate
AWC37_RS09685	COG1309	transcriptional regulator
AWC37_RS09690	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
AWC37_RS09695	COG0531	amino acid
AWC37_RS09700	COG2851	Citrate transporter
AWC37_RS09705	COG2814	Major facilitator Superfamily
AWC37_RS09710	COG0390	transport system, permease component
AWC37_RS09715	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AWC37_RS09725	COG0069	glutamate synthase activity
AWC37_RS09735	COG1363	Peptidase, m42
AWC37_RS09740	COG1028	Short-chain dehydrogenase reductase Sdr
AWC37_RS09745	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
AWC37_RS09750	COG0248	Ppx GppA phosphatase
AWC37_RS09755	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
AWC37_RS09760	COG3048	D-serine ammonia-lyase activity
AWC37_RS09770	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
AWC37_RS09775	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AWC37_RS09780	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AWC37_RS09785	COG0131	Imidazoleglycerol-phosphate dehydratase
AWC37_RS09790	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
AWC37_RS09795	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
AWC37_RS09800	COG0107	imidazoleglycerol-phosphate synthase activity
AWC37_RS09830	COG4221	oxidoreductase activity
AWC37_RS09845	COG1312	Catalyzes the dehydration of D-mannonate
AWC37_RS09850	COG1904	glucuronate isomerase
AWC37_RS09855	COG2211	Major facilitator Superfamily
AWC37_RS09875	COG3250	beta-galactosidase activity
AWC37_RS09880	COG2211	Major facilitator Superfamily
AWC37_RS09890	COG3949	Membrane
AWC37_RS09895	COG1028	Short-chain dehydrogenase reductase Sdr
AWC37_RS09900	COG2610	gluconate transmembrane transporter activity
AWC37_RS09905	COG1070	Carbohydrate kinase
AWC37_RS09910	COG1802	Transcriptional regulator
AWC37_RS09920	COG2357	RelA SpoT domain protein
AWC37_RS09925	COG4876	unkown
AWC37_RS09940	COG1289	transmembrane transporter activity
AWC37_RS09945	COG3527	Alpha-acetolactate decarboxylase
AWC37_RS09955	COG2271	Major facilitator Superfamily
AWC37_RS09960	COG0586	Pfam SNARE associated Golgi protein
AWC37_RS09965	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AWC37_RS09970	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
AWC37_RS09980	COG3949	Membrane
AWC37_RS09985	COG0471	metal ion transport
AWC37_RS09995	COG0400	carboxylic ester hydrolase activity
AWC37_RS10000	COG0346	lactoylglutathione lyase activity
AWC37_RS10005	COG0346	lactoylglutathione lyase activity
AWC37_RS10010	COG1846	Transcriptional regulator
AWC37_RS10015	COG1012	belongs to the aldehyde dehydrogenase family
AWC37_RS10030	COG1132	(ABC) transporter
AWC37_RS10035	COG1132	(ABC) transporter
AWC37_RS10045	COG2514	catechol 2,3-dioxygenase activity
AWC37_RS10050	COG0778	Nitroreductase
AWC37_RS10055	COG0561	phosphatase activity
AWC37_RS10060	COG2249	NAD(P)H dehydrogenase (quinone) activity
AWC37_RS10065	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AWC37_RS10070	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AWC37_RS10080	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AWC37_RS10085	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
AWC37_RS10090	COG3764	Sortase (surface protein transpeptidase)
AWC37_RS10100	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AWC37_RS10120	COG1129	ABC transporter
AWC37_RS10140	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
AWC37_RS10145	COG1063	alcohol dehydrogenase
AWC37_RS10150	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
AWC37_RS10165	COG2843	Capsule synthesis protein
AWC37_RS10175	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
AWC37_RS10190	COG0657	acetylesterase activity
AWC37_RS10210	COG2515	1-aminocyclopropane-1-carboxylate deaminase
AWC37_RS10225	COG2190	(PTS) system
AWC37_RS10225	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AWC37_RS10225	COG1263	PTS System
AWC37_RS10230	COG1288	antiporter activity
AWC37_RS10235	COG0028	Belongs to the TPP enzyme family
AWC37_RS10245	COG1380	Effector of murein hydrolase LrgA
AWC37_RS10250	COG0583	DNA-binding transcription factor activity
AWC37_RS10255	COG1757	Na H antiporter
AWC37_RS10260	COG3942	CHAP domain
AWC37_RS10265	COG3386	PFAM SMP-30 Gluconolaconase
AWC37_RS10280	COG3425	synthase
AWC37_RS10295	COG3655	Transcriptional regulator
AWC37_RS10300	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AWC37_RS10325	COG1473	amidohydrolase
AWC37_RS10340	COG2409	Drug exporters of the RND superfamily
AWC37_RS10350	COG1012	belongs to the aldehyde dehydrogenase family
AWC37_RS10355	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
AWC37_RS10365	COG4336	lyase activity
AWC37_RS10385	COG0471	metal ion transport
AWC37_RS10395	COG1028	Short-chain dehydrogenase reductase Sdr
AWC37_RS10400	COG0577	efflux transmembrane transporter activity
AWC37_RS10405	COG1136	(ABC) transporter
AWC37_RS10410	COG0659	secondary active sulfate transmembrane transporter activity
AWC37_RS10415	COG2217	Heavy metal translocating P-type atpase
AWC37_RS10420	COG2608	mercury ion transmembrane transporter activity
AWC37_RS10430	COG0436	Aminotransferase
AWC37_RS10435	COG1388	LysM domain
AWC37_RS10450	COG3189	MarR family transcriptional regulator
AWC37_RS10585	COG3728	DNA packaging
AWC37_RS10585	COG5484	DNA packaging
AWC37_RS10685	COG1396	sequence-specific DNA binding
AWC37_RS10700	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
AWC37_RS10705	COG1957	nucleoside hydrolase
AWC37_RS10710	COG1113	amino acid transport
AWC37_RS10715	COG0697	spore germination
AWC37_RS10740	COG3001	Fructosamine kinase
AWC37_RS10745	COG0167	dihydroorotate dehydrogenase activity
AWC37_RS10755	COG0561	phosphatase activity
AWC37_RS10765	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AWC37_RS10770	COG0531	amino acid
AWC37_RS10780	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AWC37_RS10805	COG0747	negative chemotaxis
AWC37_RS10810	COG4413	Urea transporter
AWC37_RS10815	COG0831	urea catabolic process
AWC37_RS10820	COG0832	Belongs to the urease beta subunit family
AWC37_RS10825	COG0804	urea catabolic process
AWC37_RS10830	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
AWC37_RS10835	COG0830	nickel cation binding
AWC37_RS10840	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
AWC37_RS10845	COG0829	nickel cation binding
AWC37_RS10870	COG0626	cystathionine gamma-synthase activity
AWC37_RS10875	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AWC37_RS10895	COG1940	carbohydrate kinase activity
AWC37_RS10900	COG1482	cell wall glycoprotein biosynthetic process
AWC37_RS10905	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AWC37_RS10905	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AWC37_RS10905	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AWC37_RS10910	COG3711	transcriptional antiterminator
AWC37_RS10910	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AWC37_RS10925	COG0039	L-malate dehydrogenase activity
AWC37_RS10930	COG1464	Belongs to the NlpA lipoprotein family
AWC37_RS10940	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AWC37_RS10950	COG4297	protein containing double-stranded beta helix domain
AWC37_RS10955	COG3037	sugar-specific permease SgaT UlaA
AWC37_RS10965	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AWC37_RS10970	COG3711	transcriptional antiterminator
AWC37_RS10975	COG1126	abc transporter atp-binding protein
AWC37_RS10980	COG0765	amino acid transport
AWC37_RS10985	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AWC37_RS11000	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AWC37_RS11005	COG0363	glucosamine-6-phosphate deaminase activity
AWC37_RS11010	COG1263	PTS System
AWC37_RS11010	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AWC37_RS11010	COG2190	(PTS) system
AWC37_RS11015	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AWC37_RS11020	COG2814	Major facilitator Superfamily
AWC37_RS11025	COG1620	l-lactate permease
AWC37_RS11030	COG1063	alcohol dehydrogenase
AWC37_RS11035	COG2610	gluconate transmembrane transporter activity
AWC37_RS11050	COG0431	NADPH-dependent FMN reductase
AWC37_RS11060	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AWC37_RS11065	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AWC37_RS11070	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
AWC37_RS11075	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
AWC37_RS11080	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AWC37_RS11085	COG0531	amino acid
AWC37_RS11090	COG0477	Major facilitator Superfamily
AWC37_RS11100	COG2843	Capsule synthesis protein
AWC37_RS11105	COG0778	Nitroreductase
AWC37_RS11115	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
AWC37_RS11115	COG0463	Glycosyl transferase, family 2
AWC37_RS11120	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
AWC37_RS11125	COG1012	belongs to the aldehyde dehydrogenase family
AWC37_RS11130	COG1510	regulation of RNA biosynthetic process
AWC37_RS11135	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AWC37_RS11140	COG2226	methyltransferase
AWC37_RS11155	COG0531	amino acid
AWC37_RS11160	COG1012	belongs to the aldehyde dehydrogenase family
AWC37_RS11165	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AWC37_RS11170	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AWC37_RS11180	COG2807	transmembrane transport
AWC37_RS11185	COG1476	TRANSCRIPTIONal
AWC37_RS11205	COG2764	glyoxalase bleomycin resistance protein dioxygenase
AWC37_RS11210	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
AWC37_RS11215	COG0574	Belongs to the PEP-utilizing enzyme family
AWC37_RS11215	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AWC37_RS11220	COG3835	regulator
AWC37_RS11225	COG1929	Belongs to the glycerate kinase type-1 family
AWC37_RS11235	COG3875	lactate racemase activity
AWC37_RS11240	COG1606	tRNA processing
AWC37_RS11245	COG1691	(AIR) carboxylase
AWC37_RS11250	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
AWC37_RS11255	COG0673	inositol 2-dehydrogenase activity
AWC37_RS11295	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AWC37_RS11305	COG3961	Belongs to the TPP enzyme family
AWC37_RS11310	COG1846	Transcriptional regulator
AWC37_RS11315	COG0668	transmembrane transport
AWC37_RS11325	COG0584	glycerophosphoryl diester phosphodiesterase
AWC37_RS11335	COG2814	Major facilitator Superfamily
AWC37_RS11375	COG0579	oxidoreductase
AWC37_RS11380	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
AWC37_RS11385	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
AWC37_RS11420	COG2084	Dehydrogenase
AWC37_RS11425	COG2188	Transcriptional regulator
AWC37_RS11430	COG0346	lactoylglutathione lyase activity
AWC37_RS11440	COG0431	NADPH-dependent FMN reductase
AWC37_RS11450	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
AWC37_RS11455	COG0602	queuosine metabolic process
AWC37_RS11460	COG1328	CTP reductase activity
AWC37_RS11465	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AWC37_RS11470	COG2022	thiamine diphosphate biosynthetic process
AWC37_RS11480	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AWC37_RS11490	COG1070	Carbohydrate kinase
AWC37_RS11505	COG1917	Cupin 2, conserved barrel domain protein
AWC37_RS11505	COG2207	Transcriptional regulator
AWC37_RS11520	COG1511	domain protein
AWC37_RS11525	COG1940	carbohydrate kinase activity
AWC37_RS11525	COG1846	Transcriptional regulator
AWC37_RS11530	COG2115	Belongs to the xylose isomerase family
AWC37_RS11535	COG1070	Carbohydrate kinase
AWC37_RS11540	COG0477	Major facilitator Superfamily
AWC37_RS11540	COG2814	Major facilitator Superfamily
AWC37_RS11545	COG3479	Phenolic acid decarboxylase
AWC37_RS11550	COG1695	Transcriptional regulator
AWC37_RS11560	COG1131	(ABC) transporter
AWC37_RS11575	COG2160	L-arabinose isomerase activity
AWC37_RS11580	COG0235	Class ii aldolase
AWC37_RS11590	COG1609	Transcriptional regulator
AWC37_RS11595	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AWC37_RS11595	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AWC37_RS11600	COG1054	Belongs to the UPF0176 family
AWC37_RS11605	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
AWC37_RS11610	COG1388	LysM domain
AWC37_RS11615	COG1388	LysM domain
AWC37_RS11620	COG5002	protein histidine kinase activity
AWC37_RS11640	COG2318	DinB family
AWC37_RS11650	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AWC37_RS11655	COG1012	belongs to the aldehyde dehydrogenase family
AWC37_RS11665	COG1028	Short-chain dehydrogenase reductase Sdr
AWC37_RS11670	COG3192	ethanolamine utilization protein
AWC37_RS11720	COG3414	Phosphotransferase system galactitol-specific IIB component
AWC37_RS11725	COG3775	system Galactitol-specific IIC component
AWC37_RS11730	COG1063	alcohol dehydrogenase
AWC37_RS11735	COG1063	alcohol dehydrogenase
AWC37_RS11740	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AWC37_RS11745	COG1028	Short-chain dehydrogenase reductase Sdr
AWC37_RS11750	COG1695	Transcriptional regulator
AWC37_RS11765	COG0463	Glycosyl transferase, family 2
AWC37_RS11770	COG2814	Major facilitator Superfamily
AWC37_RS11795	COG2814	Major facilitator Superfamily
AWC37_RS11810	COG0583	DNA-binding transcription factor activity
AWC37_RS11820	COG1476	TRANSCRIPTIONal
AWC37_RS11830	COG4555	ABC transporter
AWC37_RS11840	COG3250	beta-galactosidase activity
AWC37_RS11845	COG2211	Major facilitator Superfamily
AWC37_RS11850	COG2207	Transcriptional regulator
AWC37_RS11855	COG0583	DNA-binding transcription factor activity
AWC37_RS11885	COG1124	(ABC) transporter
AWC37_RS11890	COG0444	Belongs to the ABC transporter superfamily
AWC37_RS11900	COG0601	transmembrane transport
AWC37_RS11925	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AWC37_RS11930	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
AWC37_RS11945	COG2723	6-phospho-beta-galactosidase activity
AWC37_RS11950	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AWC37_RS11950	COG1263	PTS System
AWC37_RS11955	COG3711	transcriptional antiterminator
AWC37_RS11970	COG0415	Belongs to the DNA photolyase family
AWC37_RS12005	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
AWC37_RS12010	COG0702	epimerase
AWC37_RS12020	COG2814	Major facilitator Superfamily
AWC37_RS12025	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AWC37_RS12030	COG1136	(ABC) transporter
AWC37_RS12040	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
AWC37_RS12045	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
AWC37_RS12055	COG1942	4-Oxalocrotonate Tautomerase
AWC37_RS12060	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AWC37_RS12065	COG3314	Sporulation integral membrane protein YlbJ
AWC37_RS12095	COG3181	Tripartite tricarboxylate transporter family receptor
AWC37_RS12105	COG0583	DNA-binding transcription factor activity
AWC37_RS12110	COG2910	NAD(P)H-binding
AWC37_RS12115	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
AWC37_RS12120	COG1959	2 iron, 2 sulfur cluster binding
AWC37_RS12130	COG1401	restriction endodeoxyribonuclease activity
AWC37_RS12155	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
AWC37_RS12165	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
AWC37_RS12180	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
AWC37_RS12185	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
AWC37_RS12195	COG2211	Major facilitator Superfamily
AWC37_RS12210	COG5002	protein histidine kinase activity
AWC37_RS12215	COG0745	RESPONSE REGULATOR receiver
AWC37_RS12230	COG1819	glycosyl
AWC37_RS12235	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
AWC37_RS12240	COG0305	Participates in initiation and elongation during chromosome replication
AWC37_RS12245	COG0359	binds to the 23S rRNA
AWC37_RS12250	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
AWC37_RS12260	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AWC37_RS12270	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
AWC37_RS12275	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
AWC37_RS12280	COG2986	histidine ammonia-lyase
AWC37_RS12285	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AWC37_RS12290	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AWC37_RS12300	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AWC37_RS12305	COG2501	S4 domain
AWC37_RS12310	COG0592	DNA-directed DNA polymerase activity
AWC37_RS12315	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
AWC37_RS12325	COG0594	ribonuclease P activity
AWC37_RS12330	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
AWC37_RS12335	COG0445	tRNA wobble uridine modification
AWC37_RS12340	COG0357	Ribosomal RNA small subunit methyltransferase G
AWC37_RS12350	COG1966	Carbon starvation protein
AWC37_RS12355	COG2271	Major facilitator Superfamily
AWC37_RS12365	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AWC37_RS12370	COG0450	alkyl hydroperoxide reductase
AWC37_RS12380	COG0789	Transcriptional regulator
AWC37_RS12405	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AWC37_RS12410	COG0656	L-ascorbic acid biosynthetic process
AWC37_RS12415	COG0531	amino acid
AWC37_RS12420	COG1028	Short-chain dehydrogenase reductase Sdr
AWC37_RS12440	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
AWC37_RS12440	COG0463	Glycosyl transferase, family 2
AWC37_RS12445	COG0463	Glycosyl transferase, family 2
AWC37_RS12445	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
AWC37_RS12455	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
AWC37_RS12455	COG2755	lipolytic protein G-D-S-L family
AWC37_RS12470	COG1607	acyl-coa hydrolase
AWC37_RS12475	COG0583	DNA-binding transcription factor activity
AWC37_RS12480	COG0561	phosphatase activity
AWC37_RS12500	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AWC37_RS12505	COG0803	Belongs to the bacterial solute-binding protein 9 family
AWC37_RS12510	COG2239	Acts as a magnesium transporter
AWC37_RS12520	COG0318	PFAM AMP-dependent synthetase and ligase
AWC37_RS12525	COG1960	acyl-CoA dehydrogenase activity
AWC37_RS12535	COG0183	Belongs to the thiolase family
AWC37_RS12560	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
AWC37_RS12570	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
AWC37_RS12575	COG0646	methionine synthase
AWC37_RS12575	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
AWC37_RS12580	COG0626	cystathionine gamma-synthase activity
AWC37_RS12585	COG0626	cystathionine gamma-synthase activity
AWC37_RS12590	COG1475	DNA binding
AWC37_RS12595	COG0175	sulfate reduction
AWC37_RS12600	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
AWC37_RS12605	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AWC37_RS12625	COG0730	response to heat
AWC37_RS12630	COG2046	Belongs to the sulfate adenylyltransferase family
AWC37_RS12635	COG0529	Catalyzes the synthesis of activated sulfate
AWC37_RS12645	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
AWC37_RS12650	COG2226	methyltransferase
AWC37_RS12655	COG0772	Belongs to the SEDS family
AWC37_RS12670	COG2814	Major facilitator Superfamily
AWC37_RS12675	COG3759	membrane
AWC37_RS12680	COG2030	dehydratase
AWC37_RS12685	COG1733	regulation of RNA biosynthetic process
AWC37_RS12690	COG2814	Major facilitator Superfamily
AWC37_RS12695	COG1473	amidohydrolase
AWC37_RS12700	COG2814	Major facilitator Superfamily
AWC37_RS12705	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AWC37_RS12720	COG1012	belongs to the aldehyde dehydrogenase family
AWC37_RS12740	COG4978	Transcriptional regulator
AWC37_RS12740	COG0789	Transcriptional regulator
AWC37_RS12750	COG1288	antiporter activity
AWC37_RS12755	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AWC37_RS12760	COG1136	(ABC) transporter
AWC37_RS12765	COG0577	efflux transmembrane transporter activity
AWC37_RS12780	COG1454	alcohol dehydrogenase
AWC37_RS12785	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
AWC37_RS12790	COG1064	alcohol dehydrogenase
AWC37_RS12795	COG2084	Dehydrogenase
AWC37_RS12800	COG2211	Major facilitator Superfamily
AWC37_RS12805	COG1486	melibiose metabolic process
AWC37_RS12810	COG2207	Transcriptional regulator
AWC37_RS12810	COG1917	Cupin 2, conserved barrel domain protein
AWC37_RS12815	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AWC37_RS12820	COG3002	Belongs to the UPF0753 family
AWC37_RS12825	COG5609	conserved protein (DUF2294)
AWC37_RS12830	COG0668	transmembrane transport
AWC37_RS12835	COG4481	Protein conserved in bacteria
AWC37_RS12840	COG0012	GTP binding
AWC37_RS12850	COG0360	Binds together with S18 to 16S ribosomal RNA
AWC37_RS12875	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
AWC37_RS12885	COG0730	response to heat
AWC37_RS12890	COG1937	Protein conserved in bacteria
AWC37_RS12895	COG2210	Belongs to the sulfur carrier protein TusA family
AWC37_RS12900	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AWC37_RS12920	COG3266	domain, Protein
AWC37_RS12920	COG4193	domain, Protein
AWC37_RS12920	COG5632	N-Acetylmuramoyl-L-alanine amidase
AWC37_RS12930	COG0583	DNA-binding transcription factor activity
AWC37_RS12955	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AWC37_RS12960	COG4195	phage-related replication protein
AWC37_RS12975	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AWC37_RS12995	COG2076	Multidrug Resistance protein
AWC37_RS13000	COG2076	Multidrug Resistance protein
AWC37_RS13005	COG1280	lysine exporter protein (LysE YggA)
AWC37_RS13040	COG3634	alkyl hydroperoxide reductase activity
AWC37_RS13045	COG0450	alkyl hydroperoxide reductase
AWC37_RS13050	COG0753	catalase activity
AWC37_RS13055	COG0778	Nitroreductase
AWC37_RS13070	COG1760	l-serine dehydratase
AWC37_RS13075	COG1760	l-serine dehydratase
AWC37_RS13085	COG1823	symporter activity
AWC37_RS13090	COG5183	chlorophyll binding
AWC37_RS13105	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AWC37_RS13110	COG2233	PERMEase
AWC37_RS13115	COG0516	GMP reductase activity
AWC37_RS13115	COG0517	IMP dehydrogenase activity
AWC37_RS13120	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AWC37_RS13120	COG0519	Catalyzes the synthesis of GMP from XMP
AWC37_RS13160	COG1301	dicarboxylic acid transport
AWC37_RS13185	COG2814	Major facilitator Superfamily
AWC37_RS13190	COG0456	acetyltransferase
AWC37_RS13190	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
AWC37_RS13195	COG2508	Transcriptional regulator
AWC37_RS13200	COG1953	Uracil, thiamine, allantoin
AWC37_RS13205	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
AWC37_RS13215	COG0753	catalase activity
AWC37_RS13220	COG1876	peptidase activity
AWC37_RS13235	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AWC37_RS13245	COG1595	DNA-templated transcription, initiation
AWC37_RS13255	COG0406	alpha-ribazole phosphatase activity
AWC37_RS13260	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AWC37_RS13270	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AWC37_RS13275	COG3257	ureidoglycine aminohydrolase activity
AWC37_RS13280	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
AWC37_RS13285	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
AWC37_RS13290	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
AWC37_RS13295	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
AWC37_RS13310	COG2807	transmembrane transport
AWC37_RS13315	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
AWC37_RS13320	COG4195	phage-related replication protein
AWC37_RS13335	COG0789	Transcriptional regulator
AWC37_RS13360	COG2268	Band 7 protein
AWC37_RS13365	COG5646	InterPro IPR014922
AWC37_RS13370	COG1114	Component of the transport system for branched-chain amino acids
AWC37_RS13375	COG0733	neurotransmitter:sodium symporter activity
AWC37_RS13390	COG0129	dihydroxy-acid dehydratase activity
AWC37_RS13400	COG3942	CHAP domain
AWC37_RS13400	COG1388	LysM domain
AWC37_RS13410	COG0494	nUDIX hydrolase
AWC37_RS13415	COG0004	ammonium transporteR
AWC37_RS13435	COG0069	glutamate synthase activity
AWC37_RS13435	COG0067	glutamate synthase
AWC37_RS13435	COG0070	glutamate synthase
AWC37_RS13440	COG0493	'glutamate synthase
AWC37_RS13450	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AWC37_RS13450	COG1263	PTS System
AWC37_RS13455	COG0366	Alpha amylase catalytic
AWC37_RS13460	COG2188	Transcriptional regulator
AWC37_RS13470	COG3153	acetyltransferase
AWC37_RS13475	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AWC37_RS13480	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
AWC37_RS13485	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
AWC37_RS13525	COG1982	Orn Lys Arg decarboxylase major
AWC37_RS13530	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AWC37_RS13535	COG3870	Protein conserved in bacteria
AWC37_RS13540	COG0470	DNA polymerase III
AWC37_RS13545	COG1774	PSP1 C-terminal conserved region
AWC37_RS13550	COG4467	Involved in initiation control of chromosome replication
AWC37_RS13555	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
AWC37_RS13560	COG2827	Endonuclease containing a URI domain
AWC37_RS13565	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
AWC37_RS13570	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AWC37_RS13570	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AWC37_RS13575	COG0084	hydrolase, TatD family'
AWC37_RS13580	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
AWC37_RS13585	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AWC37_RS13590	COG4466	Protein conserved in bacteria
AWC37_RS13595	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
AWC37_RS13600	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AWC37_RS13605	COG0251	oxidation-reduction process
AWC37_RS13610	COG2088	sporulation resulting in formation of a cellular spore
AWC37_RS13615	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
AWC37_RS13620	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AWC37_RS13625	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
AWC37_RS13630	COG0193	aminoacyl-tRNA hydrolase activity
AWC37_RS13635	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AWC37_RS13640	COG2244	polysaccharide biosynthetic process
AWC37_RS13645	COG3956	TIGRFAM MazG family protein
AWC37_RS13650	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
AWC37_RS13660	COG1098	S1 RNA binding domain
AWC37_RS13675	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AWC37_RS13680	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
AWC37_RS13700	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AWC37_RS13705	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family