locus-tag	class	description
SXYLSMQ121_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
SXYLSMQ121_RS00010	COG0592	DNA-directed DNA polymerase activity
SXYLSMQ121_RS00015	COG2501	S4 domain
SXYLSMQ121_RS00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
SXYLSMQ121_RS00035	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
SXYLSMQ121_RS00040	COG2986	histidine ammonia-lyase
SXYLSMQ121_RS00045	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
SXYLSMQ121_RS00050	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
SXYLSMQ121_RS00060	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
SXYLSMQ121_RS00070	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
SXYLSMQ121_RS00075	COG0359	binds to the 23S rRNA
SXYLSMQ121_RS00080	COG0305	Participates in initiation and elongation during chromosome replication
SXYLSMQ121_RS00085	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
SXYLSMQ121_RS00090	COG1819	glycosyl
SXYLSMQ121_RS00105	COG0745	RESPONSE REGULATOR receiver
SXYLSMQ121_RS00110	COG5002	protein histidine kinase activity
SXYLSMQ121_RS00125	COG2211	Major facilitator Superfamily
SXYLSMQ121_RS00135	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
SXYLSMQ121_RS00140	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
SXYLSMQ121_RS00155	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
SXYLSMQ121_RS00165	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
SXYLSMQ121_RS00170	COG0514	ATP-dependent DNA helicase (RecQ)
SXYLSMQ121_RS00190	COG1401	restriction endodeoxyribonuclease activity
SXYLSMQ121_RS00200	COG1959	2 iron, 2 sulfur cluster binding
SXYLSMQ121_RS00205	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
SXYLSMQ121_RS00210	COG2910	NAD(P)H-binding
SXYLSMQ121_RS00220	COG1136	(ABC) transporter
SXYLSMQ121_RS00225	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
SXYLSMQ121_RS00240	COG0702	epimerase
SXYLSMQ121_RS00245	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
SXYLSMQ121_RS00280	COG0415	Belongs to the DNA photolyase family
SXYLSMQ121_RS00290	COG3711	transcriptional antiterminator
SXYLSMQ121_RS00295	COG1263	PTS System
SXYLSMQ121_RS00295	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SXYLSMQ121_RS00300	COG2723	6-phospho-beta-galactosidase activity
SXYLSMQ121_RS00315	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
SXYLSMQ121_RS00320	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SXYLSMQ121_RS00325	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
SXYLSMQ121_RS00330	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
SXYLSMQ121_RS00355	COG0601	transmembrane transport
SXYLSMQ121_RS00365	COG0444	Belongs to the ABC transporter superfamily
SXYLSMQ121_RS00370	COG1124	(ABC) transporter
SXYLSMQ121_RS00405	COG0583	DNA-binding transcription factor activity
SXYLSMQ121_RS00410	COG2207	Transcriptional regulator
SXYLSMQ121_RS00415	COG2211	Major facilitator Superfamily
SXYLSMQ121_RS00420	COG3250	beta-galactosidase activity
SXYLSMQ121_RS00430	COG4555	ABC transporter
SXYLSMQ121_RS00440	COG1476	TRANSCRIPTIONal
SXYLSMQ121_RS00445	COG2814	Major facilitator Superfamily
SXYLSMQ121_RS00450	COG0583	DNA-binding transcription factor activity
SXYLSMQ121_RS00465	COG2814	Major facilitator Superfamily
SXYLSMQ121_RS00490	COG2814	Major facilitator Superfamily
SXYLSMQ121_RS00495	COG0463	Glycosyl transferase, family 2
SXYLSMQ121_RS00510	COG1695	Transcriptional regulator
SXYLSMQ121_RS00515	COG1028	Short-chain dehydrogenase reductase Sdr
SXYLSMQ121_RS00520	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
SXYLSMQ121_RS00555	COG3192	ethanolamine utilization protein
SXYLSMQ121_RS00560	COG1028	Short-chain dehydrogenase reductase Sdr
SXYLSMQ121_RS00570	COG1012	belongs to the aldehyde dehydrogenase family
SXYLSMQ121_RS00575	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
SXYLSMQ121_RS00585	COG2318	DinB family
SXYLSMQ121_RS00605	COG5002	protein histidine kinase activity
SXYLSMQ121_RS00610	COG1388	LysM domain
SXYLSMQ121_RS00615	COG1388	LysM domain
SXYLSMQ121_RS00620	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
SXYLSMQ121_RS00630	COG1054	Belongs to the UPF0176 family
SXYLSMQ121_RS00635	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
SXYLSMQ121_RS00635	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
SXYLSMQ121_RS00640	COG1609	Transcriptional regulator
SXYLSMQ121_RS00650	COG0235	Class ii aldolase
SXYLSMQ121_RS00655	COG2160	L-arabinose isomerase activity
SXYLSMQ121_RS00670	COG1131	(ABC) transporter
SXYLSMQ121_RS00680	COG1695	Transcriptional regulator
SXYLSMQ121_RS00685	COG3479	Phenolic acid decarboxylase
SXYLSMQ121_RS00690	COG0477	Major facilitator Superfamily
SXYLSMQ121_RS00690	COG2814	Major facilitator Superfamily
SXYLSMQ121_RS00695	COG1070	Carbohydrate kinase
SXYLSMQ121_RS00700	COG2115	Belongs to the xylose isomerase family
SXYLSMQ121_RS00705	COG1846	Transcriptional regulator
SXYLSMQ121_RS00705	COG1940	carbohydrate kinase activity
SXYLSMQ121_RS00710	COG1511	domain protein
SXYLSMQ121_RS00725	COG1917	Cupin 2, conserved barrel domain protein
SXYLSMQ121_RS00725	COG2207	Transcriptional regulator
SXYLSMQ121_RS00735	COG1070	Carbohydrate kinase
SXYLSMQ121_RS00740	COG0352	thiamine-phosphate diphosphorylase activity
SXYLSMQ121_RS00745	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SXYLSMQ121_RS00750	COG2022	thiamine diphosphate biosynthetic process
SXYLSMQ121_RS00750	COG2104	thiamine diphosphate biosynthetic process
SXYLSMQ121_RS00755	COG2022	thiamine diphosphate biosynthetic process
SXYLSMQ121_RS00760	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
SXYLSMQ121_RS00765	COG1328	CTP reductase activity
SXYLSMQ121_RS00770	COG0602	queuosine metabolic process
SXYLSMQ121_RS00775	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
SXYLSMQ121_RS00785	COG0431	NADPH-dependent FMN reductase
SXYLSMQ121_RS00795	COG0346	lactoylglutathione lyase activity
SXYLSMQ121_RS00800	COG2188	Transcriptional regulator
SXYLSMQ121_RS00805	COG2084	Dehydrogenase
SXYLSMQ121_RS00815	COG2610	gluconate transmembrane transporter activity
SXYLSMQ121_RS00835	COG1115	amino acid carrier protein
SXYLSMQ121_RS00855	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
SXYLSMQ121_RS00860	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
SXYLSMQ121_RS00865	COG0579	oxidoreductase
SXYLSMQ121_RS00885	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
SXYLSMQ121_RS00900	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
SXYLSMQ121_RS00905	COG2814	Major facilitator Superfamily
SXYLSMQ121_RS00915	COG0584	glycerophosphoryl diester phosphodiesterase
SXYLSMQ121_RS00925	COG0668	transmembrane transport
SXYLSMQ121_RS00930	COG1846	Transcriptional regulator
SXYLSMQ121_RS00935	COG3961	Belongs to the TPP enzyme family
SXYLSMQ121_RS00945	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SXYLSMQ121_RS00985	COG0673	inositol 2-dehydrogenase activity
SXYLSMQ121_RS00990	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
SXYLSMQ121_RS00995	COG1691	(AIR) carboxylase
SXYLSMQ121_RS01000	COG1606	tRNA processing
SXYLSMQ121_RS01005	COG3875	lactate racemase activity
SXYLSMQ121_RS01015	COG1929	Belongs to the glycerate kinase type-1 family
SXYLSMQ121_RS01020	COG3835	regulator
SXYLSMQ121_RS01025	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
SXYLSMQ121_RS01025	COG0574	Belongs to the PEP-utilizing enzyme family
SXYLSMQ121_RS01030	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
SXYLSMQ121_RS01035	COG2764	glyoxalase bleomycin resistance protein dioxygenase
SXYLSMQ121_RS01055	COG1476	TRANSCRIPTIONal
SXYLSMQ121_RS01060	COG2807	transmembrane transport
SXYLSMQ121_RS01070	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SXYLSMQ121_RS01075	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
SXYLSMQ121_RS01080	COG1012	belongs to the aldehyde dehydrogenase family
SXYLSMQ121_RS01085	COG0531	amino acid
SXYLSMQ121_RS01100	COG2226	methyltransferase
SXYLSMQ121_RS01105	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
SXYLSMQ121_RS01110	COG1510	regulation of RNA biosynthetic process
SXYLSMQ121_RS01115	COG1012	belongs to the aldehyde dehydrogenase family
SXYLSMQ121_RS01120	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
SXYLSMQ121_RS01135	COG0778	Nitroreductase
SXYLSMQ121_RS01140	COG2843	Capsule synthesis protein
SXYLSMQ121_RS01145	COG1957	nucleoside hydrolase
SXYLSMQ121_RS01150	COG0477	Major facilitator Superfamily
SXYLSMQ121_RS01170	COG1131	(ABC) transporter
SXYLSMQ121_RS01175	COG0531	amino acid
SXYLSMQ121_RS01180	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
SXYLSMQ121_RS01185	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
SXYLSMQ121_RS01190	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
SXYLSMQ121_RS01195	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
SXYLSMQ121_RS01200	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
SXYLSMQ121_RS01205	COG0431	NADPH-dependent FMN reductase
SXYLSMQ121_RS01210	COG3226	Transcriptional regulator
SXYLSMQ121_RS01230	COG2610	gluconate transmembrane transporter activity
SXYLSMQ121_RS01235	COG1063	alcohol dehydrogenase
SXYLSMQ121_RS01240	COG1620	l-lactate permease
SXYLSMQ121_RS01245	COG2814	Major facilitator Superfamily
SXYLSMQ121_RS01250	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
SXYLSMQ121_RS01255	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SXYLSMQ121_RS01255	COG2190	(PTS) system
SXYLSMQ121_RS01255	COG1263	PTS System
SXYLSMQ121_RS01260	COG0363	glucosamine-6-phosphate deaminase activity
SXYLSMQ121_RS01265	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
SXYLSMQ121_RS01280	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SXYLSMQ121_RS01285	COG0765	amino acid transport
SXYLSMQ121_RS01290	COG1126	abc transporter atp-binding protein
SXYLSMQ121_RS01295	COG3711	transcriptional antiterminator
SXYLSMQ121_RS01300	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SXYLSMQ121_RS01310	COG3037	sugar-specific permease SgaT UlaA
SXYLSMQ121_RS01315	COG4297	protein containing double-stranded beta helix domain
SXYLSMQ121_RS01325	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
SXYLSMQ121_RS01335	COG1464	Belongs to the NlpA lipoprotein family
SXYLSMQ121_RS01340	COG0039	L-malate dehydrogenase activity
SXYLSMQ121_RS01355	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SXYLSMQ121_RS01355	COG3711	transcriptional antiterminator
SXYLSMQ121_RS01360	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SXYLSMQ121_RS01360	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SXYLSMQ121_RS01360	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SXYLSMQ121_RS01365	COG1482	cell wall glycoprotein biosynthetic process
SXYLSMQ121_RS01370	COG1940	carbohydrate kinase activity
SXYLSMQ121_RS01390	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
SXYLSMQ121_RS01395	COG0626	cystathionine gamma-synthase activity
SXYLSMQ121_RS01420	COG0829	nickel cation binding
SXYLSMQ121_RS01425	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
SXYLSMQ121_RS01430	COG0830	nickel cation binding
SXYLSMQ121_RS01435	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
SXYLSMQ121_RS01440	COG0804	urea catabolic process
SXYLSMQ121_RS01445	COG0832	Belongs to the urease beta subunit family
SXYLSMQ121_RS01450	COG0831	urea catabolic process
SXYLSMQ121_RS01455	COG4413	Urea transporter
SXYLSMQ121_RS01460	COG0747	negative chemotaxis
SXYLSMQ121_RS01485	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
SXYLSMQ121_RS01495	COG0531	amino acid
SXYLSMQ121_RS01500	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
SXYLSMQ121_RS01510	COG0561	phosphatase activity
SXYLSMQ121_RS01520	COG0167	dihydroorotate dehydrogenase activity
SXYLSMQ121_RS01525	COG3001	Fructosamine kinase
SXYLSMQ121_RS01550	COG0697	spore germination
SXYLSMQ121_RS01555	COG1113	amino acid transport
SXYLSMQ121_RS01570	COG3189	MarR family transcriptional regulator
SXYLSMQ121_RS01585	COG1388	LysM domain
SXYLSMQ121_RS01590	COG0436	Aminotransferase
SXYLSMQ121_RS01600	COG2608	mercury ion transmembrane transporter activity
SXYLSMQ121_RS01605	COG2217	Heavy metal translocating P-type atpase
SXYLSMQ121_RS01610	COG0659	secondary active sulfate transmembrane transporter activity
SXYLSMQ121_RS01615	COG1136	(ABC) transporter
SXYLSMQ121_RS01620	COG0577	efflux transmembrane transporter activity
SXYLSMQ121_RS01625	COG1028	Short-chain dehydrogenase reductase Sdr
SXYLSMQ121_RS01640	COG1136	(ABC) transporter
SXYLSMQ121_RS01665	COG0471	metal ion transport
SXYLSMQ121_RS01670	COG5505	Protein of unknown function (DUF819)
SXYLSMQ121_RS01685	COG4336	lyase activity
SXYLSMQ121_RS01695	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
SXYLSMQ121_RS01700	COG1012	belongs to the aldehyde dehydrogenase family
SXYLSMQ121_RS01710	COG2409	Drug exporters of the RND superfamily
SXYLSMQ121_RS01725	COG1473	amidohydrolase
SXYLSMQ121_RS01750	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
SXYLSMQ121_RS01755	COG3655	Transcriptional regulator
SXYLSMQ121_RS01765	COG3425	synthase
SXYLSMQ121_RS01780	COG3386	PFAM SMP-30 Gluconolaconase
SXYLSMQ121_RS01785	COG3942	CHAP domain
SXYLSMQ121_RS01790	COG1757	Na H antiporter
SXYLSMQ121_RS01795	COG0583	DNA-binding transcription factor activity
SXYLSMQ121_RS01800	COG1380	Effector of murein hydrolase LrgA
SXYLSMQ121_RS01810	COG0028	Belongs to the TPP enzyme family
SXYLSMQ121_RS01815	COG1288	antiporter activity
SXYLSMQ121_RS01820	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SXYLSMQ121_RS01820	COG2190	(PTS) system
SXYLSMQ121_RS01820	COG1263	PTS System
SXYLSMQ121_RS01835	COG2515	1-aminocyclopropane-1-carboxylate deaminase
SXYLSMQ121_RS01855	COG0657	acetylesterase activity
SXYLSMQ121_RS01860	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
SXYLSMQ121_RS01870	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
SXYLSMQ121_RS01880	COG2843	Capsule synthesis protein
SXYLSMQ121_RS01895	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
SXYLSMQ121_RS01900	COG1063	alcohol dehydrogenase
SXYLSMQ121_RS01905	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
SXYLSMQ121_RS01925	COG1129	ABC transporter
SXYLSMQ121_RS01945	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
SXYLSMQ121_RS01955	COG3764	Sortase (surface protein transpeptidase)
SXYLSMQ121_RS01960	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
SXYLSMQ121_RS01965	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
SXYLSMQ121_RS01975	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
SXYLSMQ121_RS01980	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
SXYLSMQ121_RS02000	COG2249	NAD(P)H dehydrogenase (quinone) activity
SXYLSMQ121_RS02005	COG0561	phosphatase activity
SXYLSMQ121_RS02010	COG0778	Nitroreductase
SXYLSMQ121_RS02015	COG2514	catechol 2,3-dioxygenase activity
SXYLSMQ121_RS02025	COG1132	(ABC) transporter
SXYLSMQ121_RS02030	COG1132	(ABC) transporter
SXYLSMQ121_RS02040	COG0803	Belongs to the bacterial solute-binding protein 9 family
SXYLSMQ121_RS02045	COG1012	belongs to the aldehyde dehydrogenase family
SXYLSMQ121_RS02050	COG1846	Transcriptional regulator
SXYLSMQ121_RS02055	COG0346	lactoylglutathione lyase activity
SXYLSMQ121_RS02060	COG0346	lactoylglutathione lyase activity
SXYLSMQ121_RS02065	COG0400	carboxylic ester hydrolase activity
SXYLSMQ121_RS02075	COG0471	metal ion transport
SXYLSMQ121_RS02080	COG3949	Membrane
SXYLSMQ121_RS02090	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
SXYLSMQ121_RS02095	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
SXYLSMQ121_RS02100	COG0586	Pfam SNARE associated Golgi protein
SXYLSMQ121_RS02105	COG2271	Major facilitator Superfamily
SXYLSMQ121_RS02115	COG3527	Alpha-acetolactate decarboxylase
SXYLSMQ121_RS02120	COG1289	transmembrane transporter activity
SXYLSMQ121_RS02125	COG2801	Transposase and inactivated derivatives
SXYLSMQ121_RS02145	COG4876	unkown
SXYLSMQ121_RS02150	COG2357	RelA SpoT domain protein
SXYLSMQ121_RS02160	COG1802	Transcriptional regulator
SXYLSMQ121_RS02165	COG1070	Carbohydrate kinase
SXYLSMQ121_RS02170	COG2610	gluconate transmembrane transporter activity
SXYLSMQ121_RS02175	COG1028	Short-chain dehydrogenase reductase Sdr
SXYLSMQ121_RS02180	COG3949	Membrane
SXYLSMQ121_RS02190	COG2211	Major facilitator Superfamily
SXYLSMQ121_RS02195	COG3250	beta-galactosidase activity
SXYLSMQ121_RS02200	COG2801	Transposase and inactivated derivatives
SXYLSMQ121_RS02220	COG0800	Aldolase
SXYLSMQ121_RS02225	COG2211	Major facilitator Superfamily
SXYLSMQ121_RS02230	COG1904	glucuronate isomerase
SXYLSMQ121_RS02235	COG1312	Catalyzes the dehydration of D-mannonate
SXYLSMQ121_RS02250	COG4221	oxidoreductase activity
SXYLSMQ121_RS02280	COG0107	imidazoleglycerol-phosphate synthase activity
SXYLSMQ121_RS02285	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
SXYLSMQ121_RS02290	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
SXYLSMQ121_RS02295	COG0131	Imidazoleglycerol-phosphate dehydratase
SXYLSMQ121_RS02300	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
SXYLSMQ121_RS02305	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
SXYLSMQ121_RS02310	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
SXYLSMQ121_RS02320	COG3048	D-serine ammonia-lyase activity
SXYLSMQ121_RS02325	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
SXYLSMQ121_RS02330	COG0248	Ppx GppA phosphatase
SXYLSMQ121_RS02335	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
SXYLSMQ121_RS02340	COG1028	Short-chain dehydrogenase reductase Sdr
SXYLSMQ121_RS02345	COG1363	Peptidase, m42
SXYLSMQ121_RS02355	COG0069	glutamate synthase activity
SXYLSMQ121_RS02365	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
SXYLSMQ121_RS02370	COG0390	transport system, permease component
SXYLSMQ121_RS02375	COG2814	Major facilitator Superfamily
SXYLSMQ121_RS02380	COG2851	Citrate transporter
SXYLSMQ121_RS02385	COG0531	amino acid
SXYLSMQ121_RS02390	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
SXYLSMQ121_RS02395	COG1309	transcriptional regulator
SXYLSMQ121_RS02400	COG3246	L-lysine catabolic process to acetate
SXYLSMQ121_RS02405	COG1250	3-hydroxyacyl-CoA dehydrogenase
SXYLSMQ121_RS02420	COG1174	glycine betaine transport
SXYLSMQ121_RS02430	COG1174	glycine betaine transport
SXYLSMQ121_RS02440	COG1346	cytolysis
SXYLSMQ121_RS02445	COG1380	Effector of murein hydrolase LrgA
SXYLSMQ121_RS02450	COG3279	Response regulator of the LytR AlgR family
SXYLSMQ121_RS02455	COG3275	phosphorelay sensor kinase activity
SXYLSMQ121_RS02465	COG4187	Peptidase family M20/M25/M40
SXYLSMQ121_RS02485	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
SXYLSMQ121_RS02495	COG0706	membrane insertase activity
SXYLSMQ121_RS02500	COG0025	NhaP-type Na H and K H
SXYLSMQ121_RS02520	COG2814	Major facilitator Superfamily
SXYLSMQ121_RS02530	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
SXYLSMQ121_RS02535	COG1388	LysM domain
SXYLSMQ121_RS02540	COG0588	phosphoglycerate mutase activity
SXYLSMQ121_RS02545	COG2814	Major facilitator Superfamily
SXYLSMQ121_RS02560	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
SXYLSMQ121_RS02565	COG3443	Belongs to the bacterial solute-binding protein 9 family
SXYLSMQ121_RS02565	COG0803	Belongs to the bacterial solute-binding protein 9 family
SXYLSMQ121_RS02570	COG2353	YceI-like domain
SXYLSMQ121_RS02580	COG1695	Transcriptional regulator
SXYLSMQ121_RS02600	COG2723	6-phospho-beta-galactosidase activity
SXYLSMQ121_RS02605	COG2190	(PTS) system
SXYLSMQ121_RS02605	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SXYLSMQ121_RS02605	COG1263	PTS System
SXYLSMQ121_RS02610	COG2188	Transcriptional regulator
SXYLSMQ121_RS02615	COG2116	formate transmembrane transporter activity
SXYLSMQ121_RS02620	COG0454	-acetyltransferase
SXYLSMQ121_RS02635	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
SXYLSMQ121_RS02640	COG2146	nitrite reductase [NAD(P)H] activity
SXYLSMQ121_RS02655	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
SXYLSMQ121_RS02660	COG1140	nitrate reductase beta subunit
SXYLSMQ121_RS02670	COG2181	nitrate reductase activity
SXYLSMQ121_RS02680	COG4585	Histidine kinase
SXYLSMQ121_RS02690	COG2223	nitrite transmembrane transporter activity
SXYLSMQ121_RS02695	COG0071	Belongs to the small heat shock protein (HSP20) family
SXYLSMQ121_RS02705	COG1846	Transcriptional regulator
SXYLSMQ121_RS02730	COG1263	PTS System
SXYLSMQ121_RS02730	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SXYLSMQ121_RS02750	COG1283	sodium-dependent phosphate transmembrane transporter activity
SXYLSMQ121_RS02755	COG1028	Short-chain dehydrogenase reductase Sdr
SXYLSMQ121_RS02760	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SXYLSMQ121_RS02765	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SXYLSMQ121_RS02770	COG1288	antiporter activity
SXYLSMQ121_RS02775	COG1349	DNA-binding transcription factor activity
SXYLSMQ121_RS02780	COG1063	alcohol dehydrogenase
SXYLSMQ121_RS02785	COG2376	Dihydroxyacetone kinase
SXYLSMQ121_RS02795	COG0698	ribose 5-phosphate isomerase
SXYLSMQ121_RS02805	COG0492	ferredoxin-NADP+ reductase activity
SXYLSMQ121_RS02815	COG2814	Major facilitator Superfamily
SXYLSMQ121_RS02820	COG0604	alcohol dehydrogenase
SXYLSMQ121_RS02840	COG1620	l-lactate permease
SXYLSMQ121_RS02845	COG0438	transferase activity, transferring glycosyl groups
SXYLSMQ121_RS02855	COG3850	Histidine kinase
SXYLSMQ121_RS02855	COG5002	protein histidine kinase activity
SXYLSMQ121_RS02860	COG0745	RESPONSE REGULATOR receiver
SXYLSMQ121_RS02865	COG0577	efflux transmembrane transporter activity
SXYLSMQ121_RS02870	COG1136	(ABC) transporter
SXYLSMQ121_RS02885	COG4640	response to antibiotic
SXYLSMQ121_RS02890	COG2814	Major facilitator Superfamily
SXYLSMQ121_RS02900	COG1566	PFAM secretion protein HlyD family protein
SXYLSMQ121_RS02905	COG2814	Major facilitator Superfamily
SXYLSMQ121_RS02930	COG0598	Magnesium transport protein CorA
SXYLSMQ121_RS02935	COG1304	FMN binding
SXYLSMQ121_RS02940	COG0786	glutamate:sodium symporter activity
SXYLSMQ121_RS02945	COG1757	Na H antiporter
SXYLSMQ121_RS02950	COG2094	Belongs to the DNA glycosylase MPG family
SXYLSMQ121_RS02955	COG3152	Membrane
SXYLSMQ121_RS02960	COG1069	ribulokinase activity
SXYLSMQ121_RS02965	COG4152	abc transporter atp-binding protein
SXYLSMQ121_RS02970	COG1668	transmembrane transport
SXYLSMQ121_RS02975	COG2017	converts alpha-aldose to the beta-anomer
SXYLSMQ121_RS02980	COG2258	MOSC domain
SXYLSMQ121_RS02985	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
SXYLSMQ121_RS02990	COG1266	CAAX protease self-immunity
SXYLSMQ121_RS02995	COG0010	Belongs to the arginase family
SXYLSMQ121_RS03000	COG0583	DNA-binding transcription factor activity
SXYLSMQ121_RS03005	COG3314	Sporulation integral membrane protein YlbJ
SXYLSMQ121_RS03010	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
SXYLSMQ121_RS03015	COG1228	amidohydrolase
SXYLSMQ121_RS03020	COG0659	secondary active sulfate transmembrane transporter activity
SXYLSMQ121_RS03025	COG1473	amidohydrolase
SXYLSMQ121_RS03030	COG1028	Short-chain dehydrogenase reductase Sdr
SXYLSMQ121_RS03035	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
SXYLSMQ121_RS03055	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SXYLSMQ121_RS03055	COG1263	PTS System
SXYLSMQ121_RS03065	COG0385	Bile acid
SXYLSMQ121_RS03070	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
SXYLSMQ121_RS03095	COG1113	amino acid transport
SXYLSMQ121_RS03100	COG1785	Belongs to the alkaline phosphatase family
SXYLSMQ121_RS03110	COG1263	PTS System
SXYLSMQ121_RS03110	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SXYLSMQ121_RS03115	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
SXYLSMQ121_RS03140	COG1316	TRANSCRIPTIONal
SXYLSMQ121_RS03145	COG3383	formate dehydrogenase (NAD+) activity
SXYLSMQ121_RS03170	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
SXYLSMQ121_RS03175	COG2076	Multidrug Resistance protein
SXYLSMQ121_RS03180	COG2076	Multidrug Resistance protein
SXYLSMQ121_RS03185	COG3942	CHAP domain
SXYLSMQ121_RS03200	COG1757	Na H antiporter
SXYLSMQ121_RS03205	COG3942	CHAP domain
SXYLSMQ121_RS03230	COG0765	amino acid transport
SXYLSMQ121_RS03235	COG0765	amino acid transport
SXYLSMQ121_RS03240	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SXYLSMQ121_RS03245	COG1126	abc transporter atp-binding protein
SXYLSMQ121_RS03250	COG1960	acyl-CoA dehydrogenase activity
SXYLSMQ121_RS03255	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
SXYLSMQ121_RS03260	COG1268	BioY protein
SXYLSMQ121_RS03270	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
SXYLSMQ121_RS03275	COG1609	Transcriptional regulator
SXYLSMQ121_RS03280	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
SXYLSMQ121_RS03285	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
SXYLSMQ121_RS03290	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
SXYLSMQ121_RS03295	COG0725	ABC transporter, periplasmic molybdate-binding protein
SXYLSMQ121_RS03300	COG4149	molybdate abc transporter
SXYLSMQ121_RS03305	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
SXYLSMQ121_RS03310	COG1510	regulation of RNA biosynthetic process
SXYLSMQ121_RS03315	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
SXYLSMQ121_RS03320	COG0521	Mo-molybdopterin cofactor biosynthetic process
SXYLSMQ121_RS03325	COG0315	cyclic pyranopterin monophosphate synthase activity
SXYLSMQ121_RS03350	COG0746	molybdenum cofactor guanylyltransferase activity
SXYLSMQ121_RS03355	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
SXYLSMQ121_RS03385	COG2348	transferase activity, transferring amino-acyl groups
SXYLSMQ121_RS03390	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
SXYLSMQ121_RS03410	COG4975	Glucose uptake
SXYLSMQ121_RS03420	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
SXYLSMQ121_RS03420	COG0551	DNA topoisomerase type I activity
SXYLSMQ121_RS03425	COG2252	PERMEase
SXYLSMQ121_RS03435	COG0051	transcription antitermination factor activity, RNA binding
SXYLSMQ121_RS03440	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
SXYLSMQ121_RS03445	COG0088	Forms part of the polypeptide exit tunnel
SXYLSMQ121_RS03450	COG0089	rRNA binding
SXYLSMQ121_RS03455	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
SXYLSMQ121_RS03460	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
SXYLSMQ121_RS03465	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
SXYLSMQ121_RS03470	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
SXYLSMQ121_RS03475	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
SXYLSMQ121_RS03480	COG0255	Belongs to the universal ribosomal protein uL29 family
SXYLSMQ121_RS03485	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
SXYLSMQ121_RS03490	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
SXYLSMQ121_RS03495	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
SXYLSMQ121_RS03500	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
SXYLSMQ121_RS03505	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
SXYLSMQ121_RS03510	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
SXYLSMQ121_RS03515	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
SXYLSMQ121_RS03520	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
SXYLSMQ121_RS03525	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
SXYLSMQ121_RS03530	COG1841	ribosomal large subunit assembly
SXYLSMQ121_RS03535	COG0200	Binds to the 23S rRNA
SXYLSMQ121_RS03540	COG0201	protein transport
SXYLSMQ121_RS03545	COG0563	adenylate kinase activity
SXYLSMQ121_RS03555	COG0257	Belongs to the bacterial ribosomal protein bL36 family
SXYLSMQ121_RS03560	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
SXYLSMQ121_RS03565	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
SXYLSMQ121_RS03570	COG0202	RNA polymerase activity
SXYLSMQ121_RS03575	COG0203	ribosomal protein L17
SXYLSMQ121_RS03580	COG1122	ATPase activity
SXYLSMQ121_RS03585	COG1122	ATPase activity
SXYLSMQ121_RS03595	COG0101	tRNA pseudouridine synthase activity
SXYLSMQ121_RS03600	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
SXYLSMQ121_RS03605	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
SXYLSMQ121_RS03615	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SXYLSMQ121_RS03620	COG2130	NADP-dependent
SXYLSMQ121_RS03625	COG0604	alcohol dehydrogenase
SXYLSMQ121_RS03630	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
SXYLSMQ121_RS03645	COG1302	Protein conserved in bacteria
SXYLSMQ121_RS03650	COG4264	IucA IucC family
SXYLSMQ121_RS03655	COG2814	Major facilitator Superfamily
SXYLSMQ121_RS03660	COG4264	IucA IucC family
SXYLSMQ121_RS03665	COG3457	Alanine racemase
SXYLSMQ121_RS03670	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
SXYLSMQ121_RS03675	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SXYLSMQ121_RS03680	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SXYLSMQ121_RS03685	COG3314	Sporulation integral membrane protein YlbJ
SXYLSMQ121_RS03690	COG2329	Antibiotic biosynthesis monooxygenase
SXYLSMQ121_RS03700	COG1988	membrane-bound metal-dependent
SXYLSMQ121_RS03705	COG4284	Utp--glucose-1-phosphate uridylyltransferase
SXYLSMQ121_RS03710	COG1272	protein, Hemolysin III
SXYLSMQ121_RS03725	COG0489	protein tyrosine kinase activity
SXYLSMQ121_RS03780	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
SXYLSMQ121_RS03790	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
SXYLSMQ121_RS03795	COG0246	Mannitol dehydrogenase
SXYLSMQ121_RS03805	COG3711	transcriptional antiterminator
SXYLSMQ121_RS03810	COG2213	PTS system mannitol-specific
SXYLSMQ121_RS03825	COG1119	ATPase activity
SXYLSMQ121_RS03860	COG0640	Transcriptional regulator
SXYLSMQ121_RS03865	COG0702	epimerase
SXYLSMQ121_RS03870	COG2186	Transcriptional regulator
SXYLSMQ121_RS03875	COG1482	cell wall glycoprotein biosynthetic process
SXYLSMQ121_RS03885	COG2855	membrane
SXYLSMQ121_RS03900	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SXYLSMQ121_RS03905	COG0783	Belongs to the Dps family
SXYLSMQ121_RS03910	COG0813	purine-nucleoside phosphorylase activity
SXYLSMQ121_RS03915	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
SXYLSMQ121_RS03920	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
SXYLSMQ121_RS03925	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
SXYLSMQ121_RS03935	COG1854	S-ribosylhomocysteine lyase activity
SXYLSMQ121_RS03955	COG5146	pantothenate kinase activity
SXYLSMQ121_RS03960	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
SXYLSMQ121_RS03970	COG0504	CTP synthase activity
SXYLSMQ121_RS03975	COG0191	fructose-bisphosphate aldolase activity
SXYLSMQ121_RS03980	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
SXYLSMQ121_RS03990	COG1012	belongs to the aldehyde dehydrogenase family
SXYLSMQ121_RS03995	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
SXYLSMQ121_RS04000	COG0254	rRNA binding
SXYLSMQ121_RS04005	COG1435	thymidine kinase activity
SXYLSMQ121_RS04010	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
SXYLSMQ121_RS04015	COG2890	protein-(glutamine-N5) methyltransferase activity
SXYLSMQ121_RS04020	COG0009	L-threonylcarbamoyladenylate synthase
SXYLSMQ121_RS04025	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
SXYLSMQ121_RS04030	COG4475	Protein of unknown function (DUF436)
SXYLSMQ121_RS04035	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
SXYLSMQ121_RS04040	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
SXYLSMQ121_RS04045	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
SXYLSMQ121_RS04055	COG0356	it plays a direct role in the translocation of protons across the membrane
SXYLSMQ121_RS04060	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
SXYLSMQ121_RS04065	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
SXYLSMQ121_RS04070	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
SXYLSMQ121_RS04075	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
SXYLSMQ121_RS04080	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
SXYLSMQ121_RS04085	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
SXYLSMQ121_RS04090	COG0355	proton-transporting ATP synthase activity, rotational mechanism
SXYLSMQ121_RS04100	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
SXYLSMQ121_RS04105	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
SXYLSMQ121_RS04115	COG0629	single-stranded DNA binding
SXYLSMQ121_RS04120	COG1388	LysM domain
SXYLSMQ121_RS04125	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
SXYLSMQ121_RS04135	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
SXYLSMQ121_RS04140	COG0352	thiamine-phosphate diphosphorylase activity
SXYLSMQ121_RS04145	COG0706	membrane insertase activity
SXYLSMQ121_RS04150	COG1418	mRNA catabolic process
SXYLSMQ121_RS04160	COG1937	Protein conserved in bacteria
SXYLSMQ121_RS04170	COG0772	Belongs to the SEDS family
SXYLSMQ121_RS04175	COG1181	Belongs to the D-alanine--D-alanine ligase family
SXYLSMQ121_RS04180	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
SXYLSMQ121_RS04185	COG0513	Belongs to the DEAD box helicase family
SXYLSMQ121_RS04195	COG3428	Bacterial PH domain
SXYLSMQ121_RS04220	COG1191	sigma factor activity
SXYLSMQ121_RS04225	COG2183	response to ionizing radiation
SXYLSMQ121_RS04230	COG3091	SprT-like family
SXYLSMQ121_RS04260	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
SXYLSMQ121_RS04265	COG0066	3-isopropylmalate dehydratase activity
SXYLSMQ121_RS04270	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
SXYLSMQ121_RS04275	COG0473	3-isopropylmalate dehydrogenase activity
SXYLSMQ121_RS04280	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
SXYLSMQ121_RS04285	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
SXYLSMQ121_RS04290	COG0440	acetolactate synthase activity
SXYLSMQ121_RS04295	COG0028	Belongs to the TPP enzyme family
SXYLSMQ121_RS04300	COG0129	dihydroxy-acid dehydratase activity
SXYLSMQ121_RS04305	COG0802	atpase or kinase
SXYLSMQ121_RS04310	COG1214	PFAM Peptidase M22, glycoprotease
SXYLSMQ121_RS04315	COG0456	acetyltransferase
SXYLSMQ121_RS04320	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
SXYLSMQ121_RS04330	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
SXYLSMQ121_RS04335	COG0488	(ABC) transporter
SXYLSMQ121_RS04340	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
SXYLSMQ121_RS04345	COG2391	methyltransferase activity
SXYLSMQ121_RS04350	COG0425	Belongs to the sulfur carrier protein TusA family
SXYLSMQ121_RS04355	COG1609	Transcriptional regulator
SXYLSMQ121_RS04360	COG1621	beta-fructofuranosidase activity
SXYLSMQ121_RS04365	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SXYLSMQ121_RS04370	COG3279	Response regulator of the LytR AlgR family
SXYLSMQ121_RS04375	COG3290	protein histidine kinase activity
SXYLSMQ121_RS04385	COG4512	PFAM Accessory gene regulator B
SXYLSMQ121_RS04390	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
SXYLSMQ121_RS04410	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
SXYLSMQ121_RS04415	COG0459	protein refolding
SXYLSMQ121_RS04435	COG1725	Transcriptional regulator
SXYLSMQ121_RS04450	COG1131	(ABC) transporter
SXYLSMQ121_RS04520	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
SXYLSMQ121_RS04525	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
SXYLSMQ121_RS04535	COG0640	Transcriptional regulator
SXYLSMQ121_RS04550	COG2706	6-phosphogluconolactonase activity
SXYLSMQ121_RS04555	COG1012	belongs to the aldehyde dehydrogenase family
SXYLSMQ121_RS04560	COG1227	inorganic diphosphatase activity
SXYLSMQ121_RS04565	COG1335	isochorismatase
SXYLSMQ121_RS04575	COG0471	metal ion transport
SXYLSMQ121_RS04580	COG0077	Prephenate dehydratase
SXYLSMQ121_RS04590	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
SXYLSMQ121_RS04595	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
SXYLSMQ121_RS04600	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
SXYLSMQ121_RS04610	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
SXYLSMQ121_RS04615	COG4496	protein, YerC YecD
SXYLSMQ121_RS04620	COG1876	peptidase activity
SXYLSMQ121_RS04625	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
SXYLSMQ121_RS04635	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
SXYLSMQ121_RS04640	COG4851	CamS sex pheromone cAM373 precursor
SXYLSMQ121_RS04645	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
SXYLSMQ121_RS04650	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
SXYLSMQ121_RS04655	COG0154	amidase activity
SXYLSMQ121_RS04660	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
SXYLSMQ121_RS04665	COG1597	lipid kinase activity
SXYLSMQ121_RS04670	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
SXYLSMQ121_RS04680	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
SXYLSMQ121_RS04690	COG1528	Iron-storage protein
SXYLSMQ121_RS04705	COG4129	membrane
SXYLSMQ121_RS04710	COG0024	Methionine aminopeptidase
SXYLSMQ121_RS04725	COG4585	Histidine kinase
SXYLSMQ121_RS04730	COG2197	response regulator
SXYLSMQ121_RS04735	COG1295	ribonuclease BN
SXYLSMQ121_RS04745	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
SXYLSMQ121_RS04750	COG4840	Belongs to the UPF0435 family
SXYLSMQ121_RS04755	COG2309	aminopeptidase activity
SXYLSMQ121_RS04760	COG1607	acyl-coa hydrolase
SXYLSMQ121_RS04765	COG0535	radical SAM domain protein
SXYLSMQ121_RS04775	COG0693	protein deglycase activity
SXYLSMQ121_RS04780	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SXYLSMQ121_RS04785	COG2137	regulation of response to DNA damage stimulus
SXYLSMQ121_RS04795	COG1134	teichoic acid transport
SXYLSMQ121_RS04805	COG1988	membrane-bound metal-dependent
SXYLSMQ121_RS04810	COG1194	a g-specific adenine glycosylase
SXYLSMQ121_RS04815	COG3557	Belongs to the UPF0374 family
SXYLSMQ121_RS04825	COG4129	membrane
SXYLSMQ121_RS04830	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
SXYLSMQ121_RS04835	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
SXYLSMQ121_RS04840	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
SXYLSMQ121_RS04845	COG0735	belongs to the Fur family
SXYLSMQ121_RS04985	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
SXYLSMQ121_RS05000	COG0765	amino acid transport
SXYLSMQ121_RS05005	COG1126	abc transporter atp-binding protein
SXYLSMQ121_RS05010	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
SXYLSMQ121_RS05020	COG0363	glucosamine-6-phosphate deaminase activity
SXYLSMQ121_RS05035	COG0114	fumarate hydratase activity
SXYLSMQ121_RS05040	COG0564	pseudouridine synthase activity
SXYLSMQ121_RS05045	COG4585	Histidine kinase
SXYLSMQ121_RS05045	COG2203	Gaf domain
SXYLSMQ121_RS05050	COG2197	response regulator
SXYLSMQ121_RS05055	COG1301	dicarboxylic acid transport
SXYLSMQ121_RS05060	COG0772	Belongs to the SEDS family
SXYLSMQ121_RS05065	COG1316	TRANSCRIPTIONal
SXYLSMQ121_RS05070	COG0730	response to heat
SXYLSMQ121_RS05080	COG1682	transport, permease protein
SXYLSMQ121_RS05095	COG0788	formyltetrahydrofolate deformylase activity
SXYLSMQ121_RS05105	COG4399	Belongs to the UPF0754 family
SXYLSMQ121_RS05110	COG3679	Belongs to the UPF0342 family
SXYLSMQ121_RS05115	COG0420	3'-5' exonuclease activity
SXYLSMQ121_RS05120	COG4717	serine-type aminopeptidase activity
SXYLSMQ121_RS05125	COG3481	metal-dependent phosphohydrolase, HD sub domain
SXYLSMQ121_RS05130	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
SXYLSMQ121_RS05145	COG0537	adenosine 5'-monophosphoramidase activity
SXYLSMQ121_RS05150	COG1131	(ABC) transporter
SXYLSMQ121_RS05155	COG4473	ABC transporter
SXYLSMQ121_RS05165	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
SXYLSMQ121_RS05170	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
SXYLSMQ121_RS05175	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
SXYLSMQ121_RS05180	COG3545	Serine hydrolase
SXYLSMQ121_RS05225	COG0300	oxidoreductase activity
SXYLSMQ121_RS05240	COG3591	Belongs to the peptidase S1B family
SXYLSMQ121_RS05260	COG0318	PFAM AMP-dependent synthetase and ligase
SXYLSMQ121_RS05270	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
SXYLSMQ121_RS05280	COG1506	peptidase
SXYLSMQ121_RS05285	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
SXYLSMQ121_RS05290	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
SXYLSMQ121_RS05300	COG0656	L-ascorbic acid biosynthetic process
SXYLSMQ121_RS05305	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
SXYLSMQ121_RS05310	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
SXYLSMQ121_RS05320	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
SXYLSMQ121_RS05340	COG1595	DNA-templated transcription, initiation
SXYLSMQ121_RS05350	COG5632	N-Acetylmuramoyl-L-alanine amidase
SXYLSMQ121_RS05350	COG4193	domain, Protein
SXYLSMQ121_RS05350	COG3266	domain, Protein
SXYLSMQ121_RS05365	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
SXYLSMQ121_RS05365	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
SXYLSMQ121_RS05370	COG0307	riboflavin synthase, alpha
SXYLSMQ121_RS05375	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
SXYLSMQ121_RS05375	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
SXYLSMQ121_RS05380	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
SXYLSMQ121_RS05390	COG2267	carboxylic ester hydrolase activity
SXYLSMQ121_RS05395	COG0039	L-malate dehydrogenase activity
SXYLSMQ121_RS05405	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
SXYLSMQ121_RS05410	COG1242	4 iron, 4 sulfur cluster binding
SXYLSMQ121_RS05415	COG2814	Major facilitator Superfamily
SXYLSMQ121_RS05420	COG0495	leucyl-tRNA aminoacylation
SXYLSMQ121_RS05430	COG2081	HI0933 family
SXYLSMQ121_RS05435	COG2244	polysaccharide biosynthetic process
SXYLSMQ121_RS05440	COG1187	pseudouridine synthase activity
SXYLSMQ121_RS05450	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
SXYLSMQ121_RS05455	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
SXYLSMQ121_RS05460	COG0510	thiamine kinase activity
SXYLSMQ121_RS05465	COG0220	tRNA (guanine-N7-)-methyltransferase activity
SXYLSMQ121_RS05470	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
SXYLSMQ121_RS05480	COG1363	Peptidase, m42
SXYLSMQ121_RS05485	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
SXYLSMQ121_RS05490	COG4848	Belongs to the UPF0354 family
SXYLSMQ121_RS05495	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SXYLSMQ121_RS05500	COG1674	ftsk spoiiie
SXYLSMQ121_RS05505	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
SXYLSMQ121_RS05510	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
SXYLSMQ121_RS05520	COG1605	Chorismate mutase
SXYLSMQ121_RS05520	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
SXYLSMQ121_RS05525	COG1609	Transcriptional regulator
SXYLSMQ121_RS05530	COG0123	including yeast histone deacetylase and acetoin utilization protein
SXYLSMQ121_RS05535	COG0454	-acetyltransferase
SXYLSMQ121_RS05540	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
SXYLSMQ121_RS05555	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
SXYLSMQ121_RS05560	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SXYLSMQ121_RS05565	COG0204	Acyl-transferase
SXYLSMQ121_RS05570	COG1263	PTS System
SXYLSMQ121_RS05570	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SXYLSMQ121_RS05580	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
SXYLSMQ121_RS05585	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
SXYLSMQ121_RS05590	COG1764	response to oxidative stress
SXYLSMQ121_RS05595	COG0584	glycerophosphoryl diester phosphodiesterase
SXYLSMQ121_RS05600	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
SXYLSMQ121_RS05605	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
SXYLSMQ121_RS05610	COG1956	GAF domain-containing protein
SXYLSMQ121_RS05615	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
SXYLSMQ121_RS05620	COG1104	cysteine desulfurase activity
SXYLSMQ121_RS05625	COG0301	tRNA thio-modification
SXYLSMQ121_RS05635	COG0616	signal peptide processing
SXYLSMQ121_RS05640	COG1714	RDD family
SXYLSMQ121_RS05645	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
SXYLSMQ121_RS05650	COG0827	DNA restriction-modification system
SXYLSMQ121_RS05655	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
SXYLSMQ121_RS05665	COG0589	response to stress
SXYLSMQ121_RS05670	COG0686	Belongs to the AlaDH PNT family
SXYLSMQ121_RS05675	COG3142	Participates in the control of copper homeostasis
SXYLSMQ121_RS05680	COG0006	proline dipeptidase activity
SXYLSMQ121_RS05685	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
SXYLSMQ121_RS05695	COG4109	DRTGG domain
SXYLSMQ121_RS05700	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
SXYLSMQ121_RS05705	COG0587	DNA-directed DNA polymerase activity
SXYLSMQ121_RS05710	COG0281	malic enzyme
SXYLSMQ121_RS05715	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
SXYLSMQ121_RS05720	COG0825	malonyl-CoA metabolic process
SXYLSMQ121_RS05725	COG0205	6-phosphofructokinase activity
SXYLSMQ121_RS05730	COG0469	pyruvate kinase activity
SXYLSMQ121_RS05735	COG1113	amino acid transport
SXYLSMQ121_RS05740	COG0372	Belongs to the citrate synthase family
SXYLSMQ121_RS05745	COG0538	isocitrate dehydrogenase activity
SXYLSMQ121_RS05750	COG0745	RESPONSE REGULATOR receiver
SXYLSMQ121_RS05755	COG5002	protein histidine kinase activity
SXYLSMQ121_RS05760	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SXYLSMQ121_RS05760	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SXYLSMQ121_RS05770	COG0237	dephospho-CoA kinase activity
SXYLSMQ121_RS05775	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
SXYLSMQ121_RS05780	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
SXYLSMQ121_RS05790	COG1484	DNA-dependent DNA replication
SXYLSMQ121_RS05795	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
SXYLSMQ121_RS05800	COG0833	amino acid
SXYLSMQ121_RS05805	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
SXYLSMQ121_RS05810	COG0291	Belongs to the bacterial ribosomal protein bL35 family
SXYLSMQ121_RS05815	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
SXYLSMQ121_RS05820	COG4112	unkown
SXYLSMQ121_RS05830	COG0544	peptidyl-prolyl cis-trans isomerase activity
SXYLSMQ121_RS05835	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
SXYLSMQ121_RS05840	COG0218	Necessary for normal cell division and for the maintenance of normal septation
SXYLSMQ121_RS05845	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
SXYLSMQ121_RS05850	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
SXYLSMQ121_RS05855	COG0181	hydroxymethylbilane synthase activity
SXYLSMQ121_RS05865	COG0113	porphobilinogen synthase activity
SXYLSMQ121_RS05870	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
SXYLSMQ121_RS05880	COG2818	Glycosylase
SXYLSMQ121_RS05885	COG0525	valine-tRNA ligase activity
SXYLSMQ121_RS05890	COG0285	dihydrofolate synthase activity
SXYLSMQ121_RS05905	COG2003	Belongs to the UPF0758 family
SXYLSMQ121_RS05930	COG0261	This protein binds to 23S rRNA in the presence of protein L20
SXYLSMQ121_RS05935	COG2868	ribosomal protein
SXYLSMQ121_RS05940	COG0211	Belongs to the bacterial ribosomal protein bL27 family
SXYLSMQ121_RS05945	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
SXYLSMQ121_RS05950	COG4492	Belongs to the UPF0735 family
SXYLSMQ121_RS05955	COG0632	four-way junction helicase activity
SXYLSMQ121_RS05960	COG2255	four-way junction helicase activity
SXYLSMQ121_RS05965	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
SXYLSMQ121_RS05970	COG0343	queuine tRNA-ribosyltransferase activity
SXYLSMQ121_RS05975	COG1862	Preprotein translocase
SXYLSMQ121_RS05980	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
SXYLSMQ121_RS05980	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
SXYLSMQ121_RS05985	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
SXYLSMQ121_RS05985	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
SXYLSMQ121_RS05995	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
SXYLSMQ121_RS06000	COG1490	D-aminoacyl-tRNA deacylase activity
SXYLSMQ121_RS06005	COG0860	N-Acetylmuramoyl-L-alanine amidase
SXYLSMQ121_RS06010	COG0124	histidyl-tRNA synthetase
SXYLSMQ121_RS06015	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
SXYLSMQ121_RS06020	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
SXYLSMQ121_RS06025	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
SXYLSMQ121_RS06030	COG1959	2 iron, 2 sulfur cluster binding
SXYLSMQ121_RS06040	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SXYLSMQ121_RS06045	COG0488	(ABC) transporter
SXYLSMQ121_RS06050	COG1104	cysteine desulfurase activity
SXYLSMQ121_RS06055	COG0482	sulfurtransferase activity
SXYLSMQ121_RS06065	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
SXYLSMQ121_RS06070	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
SXYLSMQ121_RS06075	COG4472	Bacterial protein of unknown function (DUF965)
SXYLSMQ121_RS06080	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
SXYLSMQ121_RS06085	COG3906	Belongs to the UPF0473 family
SXYLSMQ121_RS06090	COG4122	O-methyltransferase activity
SXYLSMQ121_RS06095	COG0826	peptidase U32
SXYLSMQ121_RS06100	COG0826	peptidase U32
SXYLSMQ121_RS06105	COG0572	uridine kinase
SXYLSMQ121_RS06110	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
SXYLSMQ121_RS06115	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
SXYLSMQ121_RS06120	COG1984	allophanate hydrolase subunit 2
SXYLSMQ121_RS06125	COG0508	dehydrogenase complex catalyzes the overall conversion of
SXYLSMQ121_RS06130	COG0439	Biotin carboxylase
SXYLSMQ121_RS06135	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
SXYLSMQ121_RS06140	COG1914	H( )-stimulated, divalent metal cation uptake system
SXYLSMQ121_RS06145	COG0730	response to heat
SXYLSMQ121_RS06150	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
SXYLSMQ121_RS06155	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
SXYLSMQ121_RS06160	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
SXYLSMQ121_RS06165	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
SXYLSMQ121_RS06170	COG1534	Rna-binding protein
SXYLSMQ121_RS06175	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
SXYLSMQ121_RS06180	COG1713	HD superfamily hydrolase involved in NAD metabolism
SXYLSMQ121_RS06185	COG0799	negative regulation of ribosome biogenesis
SXYLSMQ121_RS06190	COG2226	methyltransferase
SXYLSMQ121_RS06195	COG1555	photosystem II stabilization
SXYLSMQ121_RS06195	COG1596	polysaccharide export
SXYLSMQ121_RS06200	COG2131	deaminase
SXYLSMQ121_RS06205	COG0658	competence protein
SXYLSMQ121_RS06205	COG2333	competence protein COMEC
SXYLSMQ121_RS06210	COG1466	dna polymerase III delta subunit
SXYLSMQ121_RS06215	COG0268	Binds directly to 16S ribosomal RNA
SXYLSMQ121_RS06220	COG0481	GTPase activity
SXYLSMQ121_RS06225	COG0635	Involved in the biosynthesis of porphyrin-containing compound
SXYLSMQ121_RS06230	COG1420	regulation of RNA biosynthetic process
SXYLSMQ121_RS06235	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
SXYLSMQ121_RS06240	COG0443	Heat shock 70 kDa protein
SXYLSMQ121_RS06245	COG0484	heat shock protein binding
SXYLSMQ121_RS06250	COG2264	protein methyltransferase activity
SXYLSMQ121_RS06255	COG1385	rRNA (uridine-N3-)-methyltransferase activity
SXYLSMQ121_RS06260	COG0828	Belongs to the bacterial ribosomal protein bS21 family
SXYLSMQ121_RS06265	COG1030	water channel activity
SXYLSMQ121_RS06270	COG4864	UPF0365 protein
SXYLSMQ121_RS06280	COG1702	phosphate starvation-inducible protein PhoH
SXYLSMQ121_RS06285	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
SXYLSMQ121_RS06290	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
SXYLSMQ121_RS06295	COG0295	cytidine deaminase activity
SXYLSMQ121_RS06300	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
SXYLSMQ121_RS06305	COG1381	Involved in DNA repair and RecF pathway recombination
SXYLSMQ121_RS06310	COG0423	glycine-tRNA ligase activity
SXYLSMQ121_RS06315	COG0517	IMP dehydrogenase activity
SXYLSMQ121_RS06320	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
SXYLSMQ121_RS06330	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
SXYLSMQ121_RS06335	COG2384	SAM-dependent methyltransferase
SXYLSMQ121_RS06345	COG0513	Belongs to the DEAD box helicase family
SXYLSMQ121_RS06350	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
SXYLSMQ121_RS06355	COG1121	(ABC) transporter
SXYLSMQ121_RS06360	COG1108	ABC-type Mn2 Zn2 transport systems permease components
SXYLSMQ121_RS06370	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
SXYLSMQ121_RS06375	COG0768	penicillin binding
SXYLSMQ121_RS06380	COG0267	Belongs to the bacterial ribosomal protein bL33 family
SXYLSMQ121_RS06385	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
SXYLSMQ121_RS06390	COG0457	Tetratricopeptide repeat
SXYLSMQ121_RS06390	COG0705	Rhomboid family
SXYLSMQ121_RS06395	COG4483	Protein conserved in bacteria
SXYLSMQ121_RS06400	COG1940	carbohydrate kinase activity
SXYLSMQ121_RS06405	COG0011	TIGRFAM Protein of
SXYLSMQ121_RS06410	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
SXYLSMQ121_RS06415	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
SXYLSMQ121_RS06450	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
SXYLSMQ121_RS06455	COG0404	The glycine cleavage system catalyzes the degradation of glycine
SXYLSMQ121_RS06460	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
SXYLSMQ121_RS06465	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
SXYLSMQ121_RS06470	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
SXYLSMQ121_RS06475	COG0095	Lipoate-protein ligase
SXYLSMQ121_RS06490	COG0006	proline dipeptidase activity
SXYLSMQ121_RS06495	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
SXYLSMQ121_RS06500	COG0511	ligase activity, forming carbon-carbon bonds
SXYLSMQ121_RS06505	COG0439	Biotin carboxylase
SXYLSMQ121_RS06510	COG1302	Protein conserved in bacteria
SXYLSMQ121_RS06515	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
SXYLSMQ121_RS06520	COG1570	exodeoxyribonuclease VII activity
SXYLSMQ121_RS06525	COG1722	exodeoxyribonuclease VII activity
SXYLSMQ121_RS06535	COG1438	arginine binding
SXYLSMQ121_RS06540	COG0497	DNA recombination
SXYLSMQ121_RS06545	COG0280	phosphate acetyltransferase
SXYLSMQ121_RS06550	COG3426	butyrate kinase activity
SXYLSMQ121_RS06555	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SXYLSMQ121_RS06560	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
SXYLSMQ121_RS06565	COG0022	dehydrogenase e1 component
SXYLSMQ121_RS06570	COG0508	dehydrogenase complex catalyzes the overall conversion of
SXYLSMQ121_RS06590	COG4129	membrane
SXYLSMQ121_RS06595	COG2195	Cleaves the N-terminal amino acid of tripeptides
SXYLSMQ121_RS06605	COG1609	Transcriptional regulator
SXYLSMQ121_RS06610	COG0366	Alpha amylase catalytic
SXYLSMQ121_RS06620	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
SXYLSMQ121_RS06625	COG1234	tRNA 3'-trailer cleavage
SXYLSMQ121_RS06630	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
SXYLSMQ121_RS06640	COG0667	Aldo Keto reductase
SXYLSMQ121_RS06645	COG0494	nUDIX hydrolase
SXYLSMQ121_RS06650	COG0735	belongs to the Fur family
SXYLSMQ121_RS06655	COG4974	Belongs to the 'phage' integrase family
SXYLSMQ121_RS06665	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
SXYLSMQ121_RS06670	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
SXYLSMQ121_RS06675	COG1187	pseudouridine synthase activity
SXYLSMQ121_RS06680	COG0745	RESPONSE REGULATOR receiver
SXYLSMQ121_RS06695	COG1141	Ferredoxin
SXYLSMQ121_RS06705	COG0514	ATP-dependent DNA helicase (RecQ)
SXYLSMQ121_RS06710	COG1388	LysM domain
SXYLSMQ121_RS06715	COG0492	ferredoxin-NADP+ reductase activity
SXYLSMQ121_RS06725	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
SXYLSMQ121_RS06730	COG0539	negative regulation of cytoplasmic translation
SXYLSMQ121_RS06735	COG1160	GTP binding
SXYLSMQ121_RS06740	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
SXYLSMQ121_RS06755	COG2226	methyltransferase
SXYLSMQ121_RS06760	COG0142	geranyltranstransferase activity
SXYLSMQ121_RS06765	COG0105	UTP biosynthetic process
SXYLSMQ121_RS06770	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
SXYLSMQ121_RS06775	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
SXYLSMQ121_RS06780	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
SXYLSMQ121_RS06790	COG5582	Belongs to the UPF0302 family
SXYLSMQ121_RS06795	COG4347	Protein of unknown function (DUF1405)
SXYLSMQ121_RS06800	COG2738	Putative neutral zinc metallopeptidase
SXYLSMQ121_RS06805	COG1694	Mazg nucleotide pyrophosphohydrolase
SXYLSMQ121_RS06810	COG0438	transferase activity, transferring glycosyl groups
SXYLSMQ121_RS06815	COG0617	tRNA 3'-terminal CCA addition
SXYLSMQ121_RS06825	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
SXYLSMQ121_RS06825	COG1199	ATP-dependent helicase activity
SXYLSMQ121_RS06830	COG0017	Asparaginyl-tRNA synthetase
SXYLSMQ121_RS06835	COG3935	DnaD domain protein
SXYLSMQ121_RS06840	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
SXYLSMQ121_RS06850	COG4499	WXG100 protein secretion system (Wss), protein YukC
SXYLSMQ121_RS06850	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SXYLSMQ121_RS06855	COG3331	DNA recombination
SXYLSMQ121_RS06865	COG4474	Belongs to the UPF0398 family
SXYLSMQ121_RS06875	COG0116	Belongs to the methyltransferase superfamily
SXYLSMQ121_RS06880	COG2962	Rard protein
SXYLSMQ121_RS06890	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
SXYLSMQ121_RS06895	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SXYLSMQ121_RS06905	COG3545	Serine hydrolase
SXYLSMQ121_RS06910	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
SXYLSMQ121_RS06915	COG1413	lyase activity
SXYLSMQ121_RS06920	COG1413	lyase activity
SXYLSMQ121_RS06930	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
SXYLSMQ121_RS06950	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
SXYLSMQ121_RS06960	COG4479	Belongs to the UPF0346 family
SXYLSMQ121_RS06965	COG0793	Belongs to the peptidase S41A family
SXYLSMQ121_RS06975	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
SXYLSMQ121_RS06980	COG0671	phosphoesterase, PA-phosphatase related
SXYLSMQ121_RS06985	COG0745	RESPONSE REGULATOR receiver
SXYLSMQ121_RS06990	COG5002	protein histidine kinase activity
SXYLSMQ121_RS06995	COG0567	Dehydrogenase, E1 component
SXYLSMQ121_RS07000	COG0508	dehydrogenase complex catalyzes the overall conversion of
SXYLSMQ121_RS07010	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
SXYLSMQ121_RS07020	COG2207	Transcriptional regulator
SXYLSMQ121_RS07020	COG1917	Cupin 2, conserved barrel domain protein
SXYLSMQ121_RS07045	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
SXYLSMQ121_RS07050	COG1121	(ABC) transporter
SXYLSMQ121_RS07075	COG0714	Associated with various cellular activities
SXYLSMQ121_RS07080	COG4548	von Willebrand factor, type A
SXYLSMQ121_RS07085	COG1114	Component of the transport system for branched-chain amino acids
SXYLSMQ121_RS07090	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
SXYLSMQ121_RS07100	COG3853	Toxic anion resistance protein (TelA)
SXYLSMQ121_RS07110	COG1254	Belongs to the acylphosphatase family
SXYLSMQ121_RS07120	COG1278	Cold shock
SXYLSMQ121_RS07135	COG1473	amidohydrolase
SXYLSMQ121_RS07145	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
SXYLSMQ121_RS07150	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
SXYLSMQ121_RS07155	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
SXYLSMQ121_RS07160	COG0527	aspartate kinase activity
SXYLSMQ121_RS07170	COG0488	(ABC) transporter
SXYLSMQ121_RS07175	COG2996	Protein conserved in bacteria
SXYLSMQ121_RS07180	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
SXYLSMQ121_RS07185	COG0573	inorganic phosphate transmembrane transporter activity
SXYLSMQ121_RS07190	COG0581	inorganic phosphate transmembrane transporter activity
SXYLSMQ121_RS07195	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
SXYLSMQ121_RS07205	COG1164	Oligoendopeptidase f
SXYLSMQ121_RS07215	COG4607	ABC-type enterochelin transport system periplasmic component
SXYLSMQ121_RS07230	COG2348	transferase activity, transferring amino-acyl groups
SXYLSMQ121_RS07240	COG0159	tryptophan synthase activity
SXYLSMQ121_RS07245	COG0133	tryptophan synthase activity
SXYLSMQ121_RS07255	COG0134	indole-3-glycerol-phosphate synthase activity
SXYLSMQ121_RS07260	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
SXYLSMQ121_RS07265	COG0512	Glutamine amidotransferase of anthranilate synthase
SXYLSMQ121_RS07270	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
SXYLSMQ121_RS07290	COG0640	Transcriptional regulator
SXYLSMQ121_RS07300	COG0438	transferase activity, transferring glycosyl groups
SXYLSMQ121_RS07310	COG1363	Peptidase, m42
SXYLSMQ121_RS07320	COG0287	Prephenate dehydrogenase
SXYLSMQ121_RS07325	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
SXYLSMQ121_RS07330	COG1942	4-Oxalocrotonate Tautomerase
SXYLSMQ121_RS07345	COG1879	ABC-type sugar transport system periplasmic component
SXYLSMQ121_RS07350	COG1172	Belongs to the binding-protein-dependent transport system permease family
SXYLSMQ121_RS07355	COG1129	ABC transporter
SXYLSMQ121_RS07360	COG1869	D-ribose catabolic process
SXYLSMQ121_RS07365	COG1609	Transcriptional regulator
SXYLSMQ121_RS07375	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
SXYLSMQ121_RS07375	COG0392	lysyltransferase activity
SXYLSMQ121_RS07380	COG0628	permease
SXYLSMQ121_RS07390	COG3711	transcriptional antiterminator
SXYLSMQ121_RS07395	COG1115	amino acid carrier protein
SXYLSMQ121_RS07400	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
SXYLSMQ121_RS07410	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
SXYLSMQ121_RS07415	COG4841	protein insertion into membrane
SXYLSMQ121_RS07420	COG0824	Thioesterase
SXYLSMQ121_RS07425	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
SXYLSMQ121_RS07430	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
SXYLSMQ121_RS07435	COG1970	mechanosensitive ion channel activity
SXYLSMQ121_RS07440	COG0419	ATPase involved in DNA repair
SXYLSMQ121_RS07445	COG0420	3'-5' exonuclease activity
SXYLSMQ121_RS07450	COG4846	Membrane protein involved in cytochrome C biogenesis
SXYLSMQ121_RS07460	COG3763	UPF0154 protein
SXYLSMQ121_RS07480	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
SXYLSMQ121_RS07490	COG0516	GMP reductase activity
SXYLSMQ121_RS07495	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
SXYLSMQ121_RS07500	COG0267	Belongs to the bacterial ribosomal protein bL33 family
SXYLSMQ121_RS07505	COG0753	catalase activity
SXYLSMQ121_RS07510	COG0833	amino acid
SXYLSMQ121_RS07520	COG0561	phosphatase activity
SXYLSMQ121_RS07525	COG0083	homoserine kinase activity
SXYLSMQ121_RS07530	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
SXYLSMQ121_RS07535	COG0460	homoserine dehydrogenase
SXYLSMQ121_RS07540	COG0527	aspartate kinase activity
SXYLSMQ121_RS07575	COG2808	Putative FMN-binding domain
SXYLSMQ121_RS07580	COG1764	response to oxidative stress
SXYLSMQ121_RS07610	COG1388	LysM domain
SXYLSMQ121_RS07610	COG5632	N-Acetylmuramoyl-L-alanine amidase
SXYLSMQ121_RS07625	COG4974	Belongs to the 'phage' integrase family
SXYLSMQ121_RS07635	COG0789	Transcriptional regulator
SXYLSMQ121_RS07640	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
SXYLSMQ121_RS07645	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
SXYLSMQ121_RS07650	COG0386	Belongs to the glutathione peroxidase family
SXYLSMQ121_RS07655	COG1923	regulation of RNA biosynthetic process
SXYLSMQ121_RS07660	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
SXYLSMQ121_RS07670	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
SXYLSMQ121_RS07675	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
SXYLSMQ121_RS07680	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
SXYLSMQ121_RS07685	COG1619	proteins homologs of microcin C7 resistance protein MccF
SXYLSMQ121_RS07695	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
SXYLSMQ121_RS07700	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
SXYLSMQ121_RS07710	COG4550	Control of competence regulator ComK, YlbF/YmcA
SXYLSMQ121_RS07715	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
SXYLSMQ121_RS07730	COG1959	2 iron, 2 sulfur cluster binding
SXYLSMQ121_RS07740	COG1013	pyruvate-flavodoxin oxidoreductase activity
SXYLSMQ121_RS07745	COG0674	pyruvate-flavodoxin oxidoreductase activity
SXYLSMQ121_RS07745	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
SXYLSMQ121_RS07750	COG1692	metallophosphoesterase
SXYLSMQ121_RS07760	COG1418	mRNA catabolic process
SXYLSMQ121_RS07765	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
SXYLSMQ121_RS07770	COG1058	Belongs to the CinA family
SXYLSMQ121_RS07770	COG1546	Belongs to the CinA family
SXYLSMQ121_RS07790	COG0300	oxidoreductase activity
SXYLSMQ121_RS07795	COG0612	Peptidase, M16
SXYLSMQ121_RS07800	COG0612	Peptidase, M16
SXYLSMQ121_RS07805	COG2188	Transcriptional regulator
SXYLSMQ121_RS07810	COG1674	ftsk spoiiie
SXYLSMQ121_RS07815	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
SXYLSMQ121_RS07820	COG1185	polyribonucleotide nucleotidyltransferase activity
SXYLSMQ121_RS07825	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
SXYLSMQ121_RS07830	COG0196	riboflavin kinase activity
SXYLSMQ121_RS07835	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
SXYLSMQ121_RS07840	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
SXYLSMQ121_RS07855	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
SXYLSMQ121_RS07860	COG1358	cellular component organization or biogenesis
SXYLSMQ121_RS07865	COG2740	Nucleic-acid-binding protein implicated in transcription termination
SXYLSMQ121_RS07870	COG0195	Participates in both transcription termination and antitermination
SXYLSMQ121_RS07875	COG0779	Required for maturation of 30S ribosomal subunits
SXYLSMQ121_RS07880	COG2176	DNA-directed DNA polymerase activity
SXYLSMQ121_RS07885	COG0442	prolyl-tRNA aminoacylation
SXYLSMQ121_RS07895	COG4589	Belongs to the CDS family
SXYLSMQ121_RS07900	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
SXYLSMQ121_RS07905	COG0233	cytoplasmic translational termination
SXYLSMQ121_RS07910	COG0528	UMP kinase activity
SXYLSMQ121_RS07915	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
SXYLSMQ121_RS07920	COG0052	Belongs to the universal ribosomal protein uS2 family
SXYLSMQ121_RS07925	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
SXYLSMQ121_RS07930	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
SXYLSMQ121_RS07935	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
SXYLSMQ121_RS07940	COG4974	Belongs to the 'phage' integrase family
SXYLSMQ121_RS07945	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
SXYLSMQ121_RS07950	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
SXYLSMQ121_RS07955	COG0758	DNA mediated transformation
SXYLSMQ121_RS07965	COG0045	succinate-CoA ligase (ADP-forming) activity
SXYLSMQ121_RS07970	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
SXYLSMQ121_RS07980	COG4485	Bacterial membrane protein, YfhO
SXYLSMQ121_RS07990	COG0335	large ribosomal subunit rRNA binding
SXYLSMQ121_RS07995	COG0336	Belongs to the RNA methyltransferase TrmD family
SXYLSMQ121_RS08000	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
SXYLSMQ121_RS08005	COG0228	four-way junction DNA binding
SXYLSMQ121_RS08010	COG1028	Short-chain dehydrogenase reductase Sdr
SXYLSMQ121_RS08015	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SXYLSMQ121_RS08020	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
SXYLSMQ121_RS08025	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
SXYLSMQ121_RS08030	COG0552	protein localization to endoplasmic reticulum
SXYLSMQ121_RS08035	COG1196	nuclear chromosome segregation
SXYLSMQ121_RS08040	COG0571	ribonuclease III activity
SXYLSMQ121_RS08045	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SXYLSMQ121_RS08060	COG0416	fatty acid biosynthetic process
SXYLSMQ121_RS08065	COG1349	DNA-binding transcription factor activity
SXYLSMQ121_RS08075	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
SXYLSMQ121_RS08080	COG1760	l-serine dehydratase
SXYLSMQ121_RS08085	COG1760	l-serine dehydratase
SXYLSMQ121_RS08090	COG1461	Dihydroxyacetone kinase
SXYLSMQ121_RS08095	COG1302	Protein conserved in bacteria
SXYLSMQ121_RS08100	COG0227	Belongs to the bacterial ribosomal protein bL28 family
SXYLSMQ121_RS08105	COG1564	THIamine pyrophosphokinase
SXYLSMQ121_RS08110	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
SXYLSMQ121_RS08115	COG1162	GTPase activity
SXYLSMQ121_RS08130	COG0820	rRNA (adenine-C2-)-methyltransferase activity
SXYLSMQ121_RS08135	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
SXYLSMQ121_RS08135	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
SXYLSMQ121_RS08140	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
SXYLSMQ121_RS08145	COG0242	peptide deformylase activity
SXYLSMQ121_RS08160	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
SXYLSMQ121_RS08165	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
SXYLSMQ121_RS08170	COG1758	RNA polymerase activity
SXYLSMQ121_RS08175	COG0194	GDP metabolic process
SXYLSMQ121_RS08180	COG1293	RNA-binding protein homologous to eukaryotic snRNP
SXYLSMQ121_RS08195	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
SXYLSMQ121_RS08205	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
SXYLSMQ121_RS08210	COG0284	orotidine-5'-phosphate decarboxylase activity
SXYLSMQ121_RS08215	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
SXYLSMQ121_RS08220	COG0505	Belongs to the CarA family
SXYLSMQ121_RS08230	COG0540	Belongs to the ATCase OTCase family
SXYLSMQ121_RS08240	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
SXYLSMQ121_RS08245	COG0564	pseudouridine synthase activity
SXYLSMQ121_RS08250	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
SXYLSMQ121_RS08260	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
SXYLSMQ121_RS08265	COG3599	regulation of cell shape
SXYLSMQ121_RS08275	COG0762	integral membrane protein
SXYLSMQ121_RS08280	COG1799	cell septum assembly
SXYLSMQ121_RS08285	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
SXYLSMQ121_RS08290	COG1496	oxidoreductase activity
SXYLSMQ121_RS08295	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
SXYLSMQ121_RS08300	COG0849	cell division
SXYLSMQ121_RS08310	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
SXYLSMQ121_RS08315	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
SXYLSMQ121_RS08320	COG0768	penicillin binding
SXYLSMQ121_RS08325	COG4839	cell division protein FtsL
SXYLSMQ121_RS08330	COG0275	rRNA processing
SXYLSMQ121_RS08335	COG2001	Belongs to the MraZ family
SXYLSMQ121_RS08340	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
SXYLSMQ121_RS08345	COG0454	-acetyltransferase
SXYLSMQ121_RS08350	COG1011	Hydrolase
SXYLSMQ121_RS08400	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
SXYLSMQ121_RS08405	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
SXYLSMQ121_RS08410	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
SXYLSMQ121_RS08415	COG1053	succinate dehydrogenase
SXYLSMQ121_RS08420	COG2009	succinate dehydrogenase
SXYLSMQ121_RS08425	COG0322	excinuclease ABC activity
SXYLSMQ121_RS08430	COG3118	belongs to the thioredoxin family
SXYLSMQ121_RS08435	COG1193	negative regulation of DNA recombination
SXYLSMQ121_RS08440	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
SXYLSMQ121_RS08440	COG1796	DNA polymerase
SXYLSMQ121_RS08450	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
SXYLSMQ121_RS08455	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
SXYLSMQ121_RS08460	COG0072	phenylalanine-tRNA ligase activity
SXYLSMQ121_RS08465	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
SXYLSMQ121_RS08470	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
SXYLSMQ121_RS08480	COG0333	Belongs to the bacterial ribosomal protein bL32 family
SXYLSMQ121_RS08490	COG1323	Belongs to the UPF0348 family
SXYLSMQ121_RS08495	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
SXYLSMQ121_RS08500	COG0742	ribosomal rna small subunit methyltransferase
SXYLSMQ121_RS08510	COG4471	UPF0298 protein
SXYLSMQ121_RS08515	COG0584	glycerophosphoryl diester phosphodiesterase
SXYLSMQ121_RS08520	COG3679	Belongs to the UPF0342 family
SXYLSMQ121_RS08540	COG0109	protoheme IX farnesyltransferase activity
SXYLSMQ121_RS08545	COG1612	heme a metabolic process
SXYLSMQ121_RS08555	COG0772	Belongs to the SEDS family
SXYLSMQ121_RS08560	COG4838	Belongs to the UPF0358 family
SXYLSMQ121_RS08565	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
SXYLSMQ121_RS08570	COG1217	gtp-binding protein TYPA
SXYLSMQ121_RS08580	COG0483	inositol monophosphate 1-phosphatase activity
SXYLSMQ121_RS08585	COG4493	Belongs to the UPF0637 family
SXYLSMQ121_RS08595	COG1914	H( )-stimulated, divalent metal cation uptake system
SXYLSMQ121_RS08610	COG1177	transmembrane transport
SXYLSMQ121_RS08615	COG1176	ABC-type spermidine putrescine transport system, permease component I
SXYLSMQ121_RS08620	COG3842	ATPase activity
SXYLSMQ121_RS08630	COG4476	Belongs to the UPF0223 family
SXYLSMQ121_RS08660	COG0242	peptide deformylase activity
SXYLSMQ121_RS08670	COG5503	Protein of unknown function (DUF1447)
SXYLSMQ121_RS08675	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
SXYLSMQ121_RS08680	COG0569	domain protein
SXYLSMQ121_RS08685	COG1294	oxidase, subunit
SXYLSMQ121_RS08690	COG1271	oxidase subunit
SXYLSMQ121_RS08700	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
SXYLSMQ121_RS08705	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
SXYLSMQ121_RS08715	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
SXYLSMQ121_RS08730	COG4172	Belongs to the ABC transporter superfamily
SXYLSMQ121_RS08740	COG0151	Belongs to the GarS family
SXYLSMQ121_RS08745	COG0138	bifunctional purine biosynthesis protein purh
SXYLSMQ121_RS08755	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
SXYLSMQ121_RS08765	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
SXYLSMQ121_RS08770	COG0047	phosphoribosylformylglycinamidine synthase activity
SXYLSMQ121_RS08775	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
SXYLSMQ121_RS08780	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
SXYLSMQ121_RS08785	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
SXYLSMQ121_RS08790	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
SXYLSMQ121_RS08795	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
SXYLSMQ121_RS08800	COG1017	nitric oxide dioxygenase activity
SXYLSMQ121_RS08800	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
SXYLSMQ121_RS08810	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
SXYLSMQ121_RS08815	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
SXYLSMQ121_RS08820	COG1845	cytochrome c oxidase, subunit III
SXYLSMQ121_RS08825	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
SXYLSMQ121_RS08840	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
SXYLSMQ121_RS08845	COG1316	TRANSCRIPTIONal
SXYLSMQ121_RS08870	COG3594	Acyltransferase
SXYLSMQ121_RS08875	COG0436	Aminotransferase
SXYLSMQ121_RS08880	COG1846	Transcriptional regulator
SXYLSMQ121_RS08885	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
SXYLSMQ121_RS08890	COG2267	carboxylic ester hydrolase activity
SXYLSMQ121_RS08895	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
SXYLSMQ121_RS08900	COG1169	isochorismate synthase
SXYLSMQ121_RS08905	COG1575	Belongs to the MenA family. Type 1 subfamily
SXYLSMQ121_RS08915	COG2314	TM2 domain
SXYLSMQ121_RS08935	COG4903	ComK protein
SXYLSMQ121_RS08950	COG4873	Protein conserved in bacteria
SXYLSMQ121_RS08960	COG0737	Belongs to the 5'-nucleotidase family
SXYLSMQ121_RS08965	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
SXYLSMQ121_RS08970	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SXYLSMQ121_RS08975	COG0861	Integral membrane protein TerC family
SXYLSMQ121_RS08980	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
SXYLSMQ121_RS08990	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
SXYLSMQ121_RS08995	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
SXYLSMQ121_RS09000	COG2814	Major facilitator Superfamily
SXYLSMQ121_RS09005	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
SXYLSMQ121_RS09010	COG2382	esterase
SXYLSMQ121_RS09015	COG1115	amino acid carrier protein
SXYLSMQ121_RS09020	COG0628	permease
SXYLSMQ121_RS09030	COG0475	glutathione-regulated potassium exporter activity
SXYLSMQ121_RS09030	COG0569	domain protein
SXYLSMQ121_RS09035	COG2239	Acts as a magnesium transporter
SXYLSMQ121_RS09040	COG0564	pseudouridine synthase activity
SXYLSMQ121_RS09045	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
SXYLSMQ121_RS09050	COG2357	RelA SpoT domain protein
SXYLSMQ121_RS09065	COG2346	COG2346, Truncated hemoglobins
SXYLSMQ121_RS09070	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
SXYLSMQ121_RS09075	COG1164	Oligoendopeptidase f
SXYLSMQ121_RS09085	COG4862	establishment of competence for transformation
SXYLSMQ121_RS09090	COG1393	Belongs to the ArsC family
SXYLSMQ121_RS09095	COG0180	Tryptophanyl-tRNA synthetase
SXYLSMQ121_RS09100	COG4166	transmembrane transport
SXYLSMQ121_RS09105	COG4608	Belongs to the ABC transporter superfamily
SXYLSMQ121_RS09110	COG0444	Belongs to the ABC transporter superfamily
SXYLSMQ121_RS09115	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SXYLSMQ121_RS09120	COG0601	transmembrane transport
SXYLSMQ121_RS09140	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
SXYLSMQ121_RS09165	COG0561	phosphatase activity
SXYLSMQ121_RS09170	COG0446	pyridine nucleotide-disulphide oxidoreductase
SXYLSMQ121_RS09180	COG0179	Fumarylacetoacetate (FAA) hydrolase
SXYLSMQ121_RS09185	COG2311	Membrane
SXYLSMQ121_RS09190	COG1074	ATP-dependent DNA helicase activity
SXYLSMQ121_RS09195	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
SXYLSMQ121_RS09210	COG0398	Pfam SNARE associated Golgi protein
SXYLSMQ121_RS09215	COG0166	Belongs to the GPI family
SXYLSMQ121_RS09220	COG0137	argininosuccinate synthase activity
SXYLSMQ121_RS09225	COG0165	Argininosuccinate lyase
SXYLSMQ121_RS09230	COG0584	glycerophosphoryl diester phosphodiesterase
SXYLSMQ121_RS09240	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
SXYLSMQ121_RS09245	COG1902	pentaerythritol trinitrate reductase activity
SXYLSMQ121_RS09255	COG1098	S1 RNA binding domain
SXYLSMQ121_RS09260	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
SXYLSMQ121_RS09270	COG2111	Na H antiporter
SXYLSMQ121_RS09270	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
SXYLSMQ121_RS09275	COG2111	Na H antiporter
SXYLSMQ121_RS09280	COG1006	Multisubunit Na H antiporter MnhC subunit
SXYLSMQ121_RS09285	COG0651	ATP synthesis coupled electron transport
SXYLSMQ121_RS09290	COG1863	multisubunit Na H antiporter MnhE subunit
SXYLSMQ121_RS09295	COG2212	antiporter activity
SXYLSMQ121_RS09300	COG1320	monovalent cation:proton antiporter activity
SXYLSMQ121_RS09310	COG2050	protein possibly involved in aromatic compounds catabolism
SXYLSMQ121_RS09315	COG2056	Na+-H+ antiporter family
SXYLSMQ121_RS09320	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
SXYLSMQ121_RS09325	COG1252	NADH dehydrogenase
SXYLSMQ121_RS09330	COG0316	Belongs to the HesB IscA family
SXYLSMQ121_RS09335	COG4844	belongs to the
SXYLSMQ121_RS09340	COG1252	NADH dehydrogenase
SXYLSMQ121_RS09345	COG4837	Protein of unknown function (DUF1462)
SXYLSMQ121_RS09350	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
SXYLSMQ121_RS09355	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
SXYLSMQ121_RS09360	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SXYLSMQ121_RS09365	COG1696	Membrane protein involved in D-alanine export
SXYLSMQ121_RS09370	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SXYLSMQ121_RS09380	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
SXYLSMQ121_RS09385	COG0647	UMP catabolic process
SXYLSMQ121_RS09390	COG2445	Protein of unknown function DUF86
SXYLSMQ121_RS09400	COG4470	Protein conserved in bacteria
SXYLSMQ121_RS09405	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
SXYLSMQ121_RS09410	COG0737	Belongs to the 5'-nucleotidase family
SXYLSMQ121_RS09415	COG0730	response to heat
SXYLSMQ121_RS09420	COG1801	Protein of unknown function DUF72
SXYLSMQ121_RS09425	COG2070	2-Nitropropane dioxygenase
SXYLSMQ121_RS09430	COG1253	flavin adenine dinucleotide binding
SXYLSMQ121_RS09440	COG0454	-acetyltransferase
SXYLSMQ121_RS09445	COG0719	Fe-S assembly protein
SXYLSMQ121_RS09450	COG0822	iron-sulfur transferase activity
SXYLSMQ121_RS09455	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
SXYLSMQ121_RS09460	COG0719	Fe-S assembly protein
SXYLSMQ121_RS09465	COG0396	ATPase activity
SXYLSMQ121_RS09475	COG1253	flavin adenine dinucleotide binding
SXYLSMQ121_RS09485	COG1464	Belongs to the NlpA lipoprotein family
SXYLSMQ121_RS09490	COG2011	ABC-type metal ion transport system permease component
SXYLSMQ121_RS09495	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
SXYLSMQ121_RS09500	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
SXYLSMQ121_RS09505	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
SXYLSMQ121_RS09510	COG0509	glycine decarboxylation via glycine cleavage system
SXYLSMQ121_RS09515	COG1393	Belongs to the ArsC family
SXYLSMQ121_RS09520	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
SXYLSMQ121_RS09525	COG0778	Nitroreductase
SXYLSMQ121_RS09530	COG0710	3-dehydroquinate dehydratase activity
SXYLSMQ121_RS09535	COG1764	response to oxidative stress
SXYLSMQ121_RS09550	COG2851	Citrate transporter
SXYLSMQ121_RS09565	COG2314	TM2 domain
SXYLSMQ121_RS09595	COG2153	protein acetylation
SXYLSMQ121_RS09600	COG0346	lactoylglutathione lyase activity
SXYLSMQ121_RS09615	COG1073	alpha beta
SXYLSMQ121_RS09650	COG0346	lactoylglutathione lyase activity
SXYLSMQ121_RS09670	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
SXYLSMQ121_RS09675	COG0557	exoribonuclease II activity
SXYLSMQ121_RS09680	COG1647	Serine aminopeptidase, S33
SXYLSMQ121_RS09685	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
SXYLSMQ121_RS09695	COG0148	phosphopyruvate hydratase activity
SXYLSMQ121_RS09700	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
SXYLSMQ121_RS09705	COG0149	triose-phosphate isomerase activity
SXYLSMQ121_RS09710	COG0126	phosphoglycerate kinase activity
SXYLSMQ121_RS09745	COG1090	epimerase
SXYLSMQ121_RS09750	COG0740	serine-type endopeptidase activity
SXYLSMQ121_RS09760	COG1481	regulation of sporulation
SXYLSMQ121_RS09765	COG0391	Required for morphogenesis under gluconeogenic growth conditions
SXYLSMQ121_RS09770	COG1660	Displays ATPase and GTPase activities
SXYLSMQ121_RS09775	COG0492	ferredoxin-NADP+ reductase activity
SXYLSMQ121_RS09785	COG0110	maltose O-acetyltransferase activity
SXYLSMQ121_RS09790	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
SXYLSMQ121_RS09795	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
SXYLSMQ121_RS09805	COG0556	nucleotide-excision repair
SXYLSMQ121_RS09820	COG1388	LysM domain
SXYLSMQ121_RS09820	COG3942	CHAP domain
SXYLSMQ121_RS09825	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
SXYLSMQ121_RS09830	COG0653	protein targeting
SXYLSMQ121_RS09835	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
SXYLSMQ121_RS09840	COG1040	competence protein
SXYLSMQ121_RS09845	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
SXYLSMQ121_RS09855	COG1739	Uncharacterized protein family UPF0029
SXYLSMQ121_RS09860	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
SXYLSMQ121_RS09865	COG2199	diguanylate cyclase activity
SXYLSMQ121_RS09880	COG2195	Cleaves the N-terminal amino acid of tripeptides
SXYLSMQ121_RS09885	COG1929	Belongs to the glycerate kinase type-1 family
SXYLSMQ121_RS09905	COG0812	UDP-N-acetylmuramate dehydrogenase activity
SXYLSMQ121_RS09920	COG4607	ABC-type enterochelin transport system periplasmic component
SXYLSMQ121_RS09925	COG4604	ABC transporter, ATP-binding protein
SXYLSMQ121_RS09930	COG4605	iron ion homeostasis
SXYLSMQ121_RS09935	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SXYLSMQ121_RS09940	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
SXYLSMQ121_RS09945	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
SXYLSMQ121_RS09950	COG1780	Probably involved in ribonucleotide reductase function
SXYLSMQ121_RS09960	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
SXYLSMQ121_RS09965	COG3104	oligopeptide transport
SXYLSMQ121_RS09970	COG3104	oligopeptide transport
SXYLSMQ121_RS09975	COG1597	lipid kinase activity
SXYLSMQ121_RS09985	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
SXYLSMQ121_RS09990	COG1174	glycine betaine transport
SXYLSMQ121_RS10000	COG0514	ATP-dependent DNA helicase (RecQ)
SXYLSMQ121_RS10005	COG0488	(ABC) transporter
SXYLSMQ121_RS10015	COG1368	sulfuric ester hydrolase activity
SXYLSMQ121_RS10025	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
SXYLSMQ121_RS10035	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
SXYLSMQ121_RS10040	COG0512	Glutamine amidotransferase of anthranilate synthase
SXYLSMQ121_RS10040	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
SXYLSMQ121_RS10045	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
SXYLSMQ121_RS10050	COG0720	synthase
SXYLSMQ121_RS10055	COG0602	queuosine metabolic process
SXYLSMQ121_RS10070	COG0463	Glycosyl transferase, family 2
SXYLSMQ121_RS10075	COG0656	L-ascorbic acid biosynthetic process
SXYLSMQ121_RS10080	COG1253	flavin adenine dinucleotide binding
SXYLSMQ121_RS10085	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
SXYLSMQ121_RS10090	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SXYLSMQ121_RS10090	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SXYLSMQ121_RS10090	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SXYLSMQ121_RS10095	COG1105	Belongs to the carbohydrate kinase PfkB family
SXYLSMQ121_RS10100	COG1349	DNA-binding transcription factor activity
SXYLSMQ121_RS10105	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
SXYLSMQ121_RS10110	COG1210	Utp--glucose-1-phosphate uridylyltransferase
SXYLSMQ121_RS10140	COG0039	L-malate dehydrogenase activity
SXYLSMQ121_RS10145	COG0586	Pfam SNARE associated Golgi protein
SXYLSMQ121_RS10155	COG4989	oxidoreductase activity
SXYLSMQ121_RS10170	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
SXYLSMQ121_RS10175	COG4988	ABC transporter
SXYLSMQ121_RS10180	COG1968	undecaprenyl-diphosphatase activity
SXYLSMQ121_RS10190	COG1671	Belongs to the UPF0178 family
SXYLSMQ121_RS10195	COG1611	Belongs to the LOG family
SXYLSMQ121_RS10200	COG1279	arginine transmembrane transporter activity
SXYLSMQ121_RS10205	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SXYLSMQ121_RS10235	COG2814	Major facilitator Superfamily
SXYLSMQ121_RS10240	COG2839	Protein conserved in bacteria
SXYLSMQ121_RS10245	COG2814	Major facilitator Superfamily
SXYLSMQ121_RS10250	COG0583	DNA-binding transcription factor activity
SXYLSMQ121_RS10260	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
SXYLSMQ121_RS10270	COG0217	transcriptional regulatory protein
SXYLSMQ121_RS10290	COG3942	CHAP domain
SXYLSMQ121_RS10290	COG1388	LysM domain
SXYLSMQ121_RS10295	COG0306	phosphate transporter
SXYLSMQ121_RS10300	COG1392	Phosphate transport regulator
SXYLSMQ121_RS10305	COG2205	protein histidine kinase activity
SXYLSMQ121_RS10310	COG0745	RESPONSE REGULATOR receiver
SXYLSMQ121_RS10315	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
SXYLSMQ121_RS10325	COG0657	acetylesterase activity
SXYLSMQ121_RS10330	COG3949	Membrane
SXYLSMQ121_RS10340	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
SXYLSMQ121_RS10345	COG1461	Dihydroxyacetone kinase
SXYLSMQ121_RS10350	COG2376	Dihydroxyacetone kinase
SXYLSMQ121_RS10355	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SXYLSMQ121_RS10360	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SXYLSMQ121_RS10365	COG1120	ATPase activity
SXYLSMQ121_RS10370	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
SXYLSMQ121_RS10375	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
SXYLSMQ121_RS10380	COG1132	(ABC) transporter
SXYLSMQ121_RS10385	COG1686	Belongs to the peptidase S11 family
SXYLSMQ121_RS10390	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
SXYLSMQ121_RS10400	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
SXYLSMQ121_RS10405	COG1682	transport, permease protein
SXYLSMQ121_RS10410	COG1134	teichoic acid transport
SXYLSMQ121_RS10415	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
SXYLSMQ121_RS10435	COG1108	ABC-type Mn2 Zn2 transport systems permease components
SXYLSMQ121_RS10440	COG0803	Belongs to the bacterial solute-binding protein 9 family
SXYLSMQ121_RS10450	COG1320	monovalent cation:proton antiporter activity
SXYLSMQ121_RS10455	COG2212	antiporter activity
SXYLSMQ121_RS10460	COG1863	multisubunit Na H antiporter MnhE subunit
SXYLSMQ121_RS10465	COG0651	ATP synthesis coupled electron transport
SXYLSMQ121_RS10470	COG1006	Multisubunit Na H antiporter MnhC subunit
SXYLSMQ121_RS10475	COG2111	Na H antiporter
SXYLSMQ121_RS10480	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
SXYLSMQ121_RS10480	COG2111	Na H antiporter
SXYLSMQ121_RS10520	COG2267	carboxylic ester hydrolase activity
SXYLSMQ121_RS10540	COG0546	phosphoglycolate phosphatase activity
SXYLSMQ121_RS10545	COG4139	cobalamin transport
SXYLSMQ121_RS10550	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
SXYLSMQ121_RS10560	COG0018	arginyl-trna synthetase
SXYLSMQ121_RS10575	COG1078	dGTPase activity
SXYLSMQ121_RS10580	COG0456	acetyltransferase
SXYLSMQ121_RS10585	COG0655	NAD(P)H dehydrogenase (quinone) activity
SXYLSMQ121_RS10590	COG0667	Aldo Keto reductase
SXYLSMQ121_RS10595	COG4844	belongs to the
SXYLSMQ121_RS10600	COG1082	Xylose isomerase domain protein TIM barrel
SXYLSMQ121_RS10605	COG0673	inositol 2-dehydrogenase activity
SXYLSMQ121_RS10615	COG0673	inositol 2-dehydrogenase activity
SXYLSMQ121_RS10620	COG1737	Transcriptional regulator
SXYLSMQ121_RS10625	COG1263	PTS System
SXYLSMQ121_RS10625	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SXYLSMQ121_RS10640	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
SXYLSMQ121_RS10645	COG0095	Lipoate-protein ligase
SXYLSMQ121_RS10650	COG0280	phosphate acetyltransferase
SXYLSMQ121_RS10655	COG3253	May function as heme-dependent peroxidase
SXYLSMQ121_RS10675	COG2801	Transposase and inactivated derivatives
SXYLSMQ121_RS10685	COG2363	Small membrane protein
SXYLSMQ121_RS10695	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
SXYLSMQ121_RS10700	COG0351	phosphomethylpyrimidine kinase
SXYLSMQ121_RS10730	COG0183	Belongs to the thiolase family
SXYLSMQ121_RS10735	COG0318	PFAM AMP-dependent synthetase and ligase
SXYLSMQ121_RS10745	COG3493	citrate carrier protein
SXYLSMQ121_RS10750	COG0384	phenazine biosynthesis protein PhzF
SXYLSMQ121_RS10755	COG2329	Antibiotic biosynthesis monooxygenase
SXYLSMQ121_RS10775	COG2832	Protein of unknown function (DUF454)
SXYLSMQ121_RS10780	COG4565	transcriptional regulatory protein
SXYLSMQ121_RS10785	COG3290	protein histidine kinase activity
SXYLSMQ121_RS10790	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
SXYLSMQ121_RS10795	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
SXYLSMQ121_RS10800	COG0363	glucosamine-6-phosphate deaminase activity
SXYLSMQ121_RS10810	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
SXYLSMQ121_RS10815	COG1469	GTP cyclohydrolase I activity
SXYLSMQ121_RS10830	COG0431	NADPH-dependent FMN reductase
SXYLSMQ121_RS10835	COG0561	phosphatase activity
SXYLSMQ121_RS10845	COG1428	Deoxynucleoside kinase
SXYLSMQ121_RS10850	COG1428	Deoxynucleoside kinase
SXYLSMQ121_RS10860	COG0546	phosphoglycolate phosphatase activity
SXYLSMQ121_RS10880	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
SXYLSMQ121_RS10895	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
SXYLSMQ121_RS10900	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SXYLSMQ121_RS10920	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
SXYLSMQ121_RS10930	COG2824	Alkylphosphonate utilization operon protein PhnA
SXYLSMQ121_RS10940	COG1113	amino acid transport
SXYLSMQ121_RS10945	COG3239	Fatty acid desaturase
SXYLSMQ121_RS10955	COG2040	homocysteine
SXYLSMQ121_RS10960	COG0833	amino acid
SXYLSMQ121_RS10970	COG0010	Belongs to the arginase family
SXYLSMQ121_RS10975	COG1914	H( )-stimulated, divalent metal cation uptake system
SXYLSMQ121_RS10990	COG1069	ribulokinase activity
SXYLSMQ121_RS10995	COG1063	alcohol dehydrogenase
SXYLSMQ121_RS11000	COG2814	Major facilitator Superfamily
SXYLSMQ121_RS11005	COG1349	DNA-binding transcription factor activity
SXYLSMQ121_RS11010	COG1132	(ABC) transporter
SXYLSMQ121_RS11015	COG1028	Short-chain dehydrogenase reductase Sdr
SXYLSMQ121_RS11020	COG1312	Catalyzes the dehydration of D-mannonate
SXYLSMQ121_RS11025	COG1904	glucuronate isomerase
SXYLSMQ121_RS11045	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SXYLSMQ121_RS11060	COG0583	DNA-binding transcription factor activity
SXYLSMQ121_RS11080	COG0667	Aldo Keto reductase
SXYLSMQ121_RS11100	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
SXYLSMQ121_RS11105	COG1686	Belongs to the peptidase S11 family
SXYLSMQ121_RS11120	COG1028	Short-chain dehydrogenase reductase Sdr
SXYLSMQ121_RS11125	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
SXYLSMQ121_RS11130	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
SXYLSMQ121_RS11170	COG1473	amidohydrolase
SXYLSMQ121_RS11175	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
SXYLSMQ121_RS11180	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
SXYLSMQ121_RS11185	COG0049	tRNA binding
SXYLSMQ121_RS11190	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
SXYLSMQ121_RS11200	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
SXYLSMQ121_RS11205	COG0085	RNA polymerase activity
SXYLSMQ121_RS11210	COG2813	Specifically methylates the guanine in position
SXYLSMQ121_RS11215	COG0222	ribosome binding
SXYLSMQ121_RS11220	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
SXYLSMQ121_RS11225	COG0081	regulation of translation
SXYLSMQ121_RS11230	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
SXYLSMQ121_RS11235	COG0250	Participates in transcription elongation, termination and antitermination
SXYLSMQ121_RS11255	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
SXYLSMQ121_RS11260	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
SXYLSMQ121_RS11265	COG0215	cysteine-tRNA ligase activity
SXYLSMQ121_RS11270	COG1045	serine acetyltransferase
SXYLSMQ121_RS11275	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
SXYLSMQ121_RS11280	COG4956	integral membrane protein (PIN domain superfamily)
SXYLSMQ121_RS11285	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
SXYLSMQ121_RS11290	COG0542	response to heat
SXYLSMQ121_RS11295	COG3869	Catalyzes the specific phosphorylation of arginine residues in
SXYLSMQ121_RS11300	COG3880	PFAM UvrB UvrC protein
SXYLSMQ121_RS11305	COG4463	regulation of RNA biosynthetic process
SXYLSMQ121_RS11310	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
SXYLSMQ121_RS11315	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
SXYLSMQ121_RS11320	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
SXYLSMQ121_RS11325	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SXYLSMQ121_RS11410	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
SXYLSMQ121_RS11415	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
SXYLSMQ121_RS11435	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
SXYLSMQ121_RS11440	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
SXYLSMQ121_RS11455	COG1098	S1 RNA binding domain
SXYLSMQ121_RS11465	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
SXYLSMQ121_RS11470	COG3956	TIGRFAM MazG family protein
SXYLSMQ121_RS11475	COG2244	polysaccharide biosynthetic process
SXYLSMQ121_RS11480	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
SXYLSMQ121_RS11485	COG0193	aminoacyl-tRNA hydrolase activity
SXYLSMQ121_RS11490	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
SXYLSMQ121_RS11495	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
SXYLSMQ121_RS11500	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
SXYLSMQ121_RS11505	COG2088	sporulation resulting in formation of a cellular spore
SXYLSMQ121_RS11510	COG0251	oxidation-reduction process
SXYLSMQ121_RS11515	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
SXYLSMQ121_RS11520	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
SXYLSMQ121_RS11525	COG4466	Protein conserved in bacteria
SXYLSMQ121_RS11530	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
SXYLSMQ121_RS11535	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
SXYLSMQ121_RS11540	COG0084	hydrolase, TatD family'
SXYLSMQ121_RS11545	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SXYLSMQ121_RS11545	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SXYLSMQ121_RS11550	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
SXYLSMQ121_RS11555	COG2827	Endonuclease containing a URI domain
SXYLSMQ121_RS11560	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
SXYLSMQ121_RS11565	COG4467	Involved in initiation control of chromosome replication
SXYLSMQ121_RS11570	COG1774	PSP1 C-terminal conserved region
SXYLSMQ121_RS11575	COG0470	DNA polymerase III
SXYLSMQ121_RS11580	COG3870	Protein conserved in bacteria
SXYLSMQ121_RS11585	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
SXYLSMQ121_RS11590	COG1982	Orn Lys Arg decarboxylase major
SXYLSMQ121_RS11595	COG2801	Transposase and inactivated derivatives
SXYLSMQ121_RS11635	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
SXYLSMQ121_RS11640	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
SXYLSMQ121_RS11645	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
SXYLSMQ121_RS11650	COG3153	acetyltransferase
SXYLSMQ121_RS11655	COG2188	Transcriptional regulator
SXYLSMQ121_RS11660	COG0366	Alpha amylase catalytic
SXYLSMQ121_RS11665	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SXYLSMQ121_RS11665	COG1263	PTS System
SXYLSMQ121_RS11675	COG0493	'glutamate synthase
SXYLSMQ121_RS11680	COG0069	glutamate synthase activity
SXYLSMQ121_RS11680	COG0070	glutamate synthase
SXYLSMQ121_RS11680	COG0067	glutamate synthase
SXYLSMQ121_RS11700	COG0004	ammonium transporteR
SXYLSMQ121_RS11705	COG0494	nUDIX hydrolase
SXYLSMQ121_RS11715	COG1388	LysM domain
SXYLSMQ121_RS11715	COG3942	CHAP domain
SXYLSMQ121_RS11725	COG0129	dihydroxy-acid dehydratase activity
SXYLSMQ121_RS11735	COG0733	neurotransmitter:sodium symporter activity
SXYLSMQ121_RS11740	COG1114	Component of the transport system for branched-chain amino acids
SXYLSMQ121_RS11745	COG5646	InterPro IPR014922
SXYLSMQ121_RS11750	COG2268	Band 7 protein
SXYLSMQ121_RS11775	COG0789	Transcriptional regulator
SXYLSMQ121_RS11790	COG4195	phage-related replication protein
SXYLSMQ121_RS11795	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
SXYLSMQ121_RS11800	COG2807	transmembrane transport
SXYLSMQ121_RS11815	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
SXYLSMQ121_RS11820	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
SXYLSMQ121_RS11825	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
SXYLSMQ121_RS11830	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
SXYLSMQ121_RS11835	COG3257	ureidoglycine aminohydrolase activity
SXYLSMQ121_RS11840	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
SXYLSMQ121_RS11850	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
SXYLSMQ121_RS11855	COG0406	alpha-ribazole phosphatase activity
SXYLSMQ121_RS11865	COG1595	DNA-templated transcription, initiation
SXYLSMQ121_RS11875	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
SXYLSMQ121_RS11885	COG2801	Transposase and inactivated derivatives
SXYLSMQ121_RS11895	COG1876	peptidase activity
SXYLSMQ121_RS11900	COG0753	catalase activity
SXYLSMQ121_RS11910	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
SXYLSMQ121_RS11915	COG1953	Uracil, thiamine, allantoin
SXYLSMQ121_RS11920	COG2508	Transcriptional regulator
SXYLSMQ121_RS11925	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
SXYLSMQ121_RS11925	COG0456	acetyltransferase
SXYLSMQ121_RS11930	COG2814	Major facilitator Superfamily
SXYLSMQ121_RS11935	COG0583	DNA-binding transcription factor activity
SXYLSMQ121_RS11940	COG2814	Major facilitator Superfamily
SXYLSMQ121_RS11965	COG1301	dicarboxylic acid transport
SXYLSMQ121_RS12000	COG3591	Belongs to the peptidase S1B family
SXYLSMQ121_RS12005	COG0519	Catalyzes the synthesis of GMP from XMP
SXYLSMQ121_RS12005	COG0518	GMP synthase (glutamine-hydrolyzing) activity
SXYLSMQ121_RS12010	COG0517	IMP dehydrogenase activity
SXYLSMQ121_RS12010	COG0516	GMP reductase activity
SXYLSMQ121_RS12015	COG2233	PERMEase
SXYLSMQ121_RS12020	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
SXYLSMQ121_RS12035	COG5183	chlorophyll binding
SXYLSMQ121_RS12040	COG1823	symporter activity
SXYLSMQ121_RS12050	COG1760	l-serine dehydratase
SXYLSMQ121_RS12055	COG1760	l-serine dehydratase
SXYLSMQ121_RS12070	COG0778	Nitroreductase
SXYLSMQ121_RS12075	COG0753	catalase activity
SXYLSMQ121_RS12080	COG0450	alkyl hydroperoxide reductase
SXYLSMQ121_RS12085	COG3634	alkyl hydroperoxide reductase activity
SXYLSMQ121_RS12100	COG0406	alpha-ribazole phosphatase activity
SXYLSMQ121_RS12120	COG1280	lysine exporter protein (LysE YggA)
SXYLSMQ121_RS12125	COG2076	Multidrug Resistance protein
SXYLSMQ121_RS12130	COG2076	Multidrug Resistance protein
SXYLSMQ121_RS12150	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SXYLSMQ121_RS12165	COG4195	phage-related replication protein
SXYLSMQ121_RS12170	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
SXYLSMQ121_RS12195	COG0583	DNA-binding transcription factor activity
SXYLSMQ121_RS12205	COG3266	domain, Protein
SXYLSMQ121_RS12205	COG4193	domain, Protein
SXYLSMQ121_RS12205	COG5632	N-Acetylmuramoyl-L-alanine amidase
SXYLSMQ121_RS12220	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
SXYLSMQ121_RS12245	COG0360	Binds together with S18 to 16S ribosomal RNA
SXYLSMQ121_RS12255	COG0012	GTP binding
SXYLSMQ121_RS12260	COG4481	Protein conserved in bacteria
SXYLSMQ121_RS12265	COG0668	transmembrane transport
SXYLSMQ121_RS12270	COG5609	conserved protein (DUF2294)
SXYLSMQ121_RS12275	COG3002	Belongs to the UPF0753 family
SXYLSMQ121_RS12280	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
SXYLSMQ121_RS12285	COG1917	Cupin 2, conserved barrel domain protein
SXYLSMQ121_RS12285	COG2207	Transcriptional regulator
SXYLSMQ121_RS12290	COG1486	melibiose metabolic process
SXYLSMQ121_RS12295	COG2211	Major facilitator Superfamily
SXYLSMQ121_RS12300	COG2610	gluconate transmembrane transporter activity
SXYLSMQ121_RS12310	COG2084	Dehydrogenase
SXYLSMQ121_RS12315	COG1064	alcohol dehydrogenase
SXYLSMQ121_RS12320	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
SXYLSMQ121_RS12345	COG1733	regulation of RNA biosynthetic process
SXYLSMQ121_RS12355	COG0577	efflux transmembrane transporter activity
SXYLSMQ121_RS12360	COG1136	(ABC) transporter
SXYLSMQ121_RS12370	COG1288	antiporter activity
SXYLSMQ121_RS12380	COG0789	Transcriptional regulator
SXYLSMQ121_RS12380	COG4978	Transcriptional regulator
SXYLSMQ121_RS12400	COG1012	belongs to the aldehyde dehydrogenase family
SXYLSMQ121_RS12410	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
SXYLSMQ121_RS12415	COG2814	Major facilitator Superfamily
SXYLSMQ121_RS12420	COG1473	amidohydrolase
SXYLSMQ121_RS12425	COG2814	Major facilitator Superfamily
SXYLSMQ121_RS12430	COG1733	regulation of RNA biosynthetic process
SXYLSMQ121_RS12435	COG2030	dehydratase
SXYLSMQ121_RS12440	COG3759	membrane
SXYLSMQ121_RS12445	COG2814	Major facilitator Superfamily
SXYLSMQ121_RS12460	COG0772	Belongs to the SEDS family
SXYLSMQ121_RS12465	COG2226	methyltransferase
SXYLSMQ121_RS12480	COG0529	Catalyzes the synthesis of activated sulfate
SXYLSMQ121_RS12485	COG2046	Belongs to the sulfate adenylyltransferase family
SXYLSMQ121_RS12490	COG0730	response to heat
SXYLSMQ121_RS12510	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
SXYLSMQ121_RS12515	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
SXYLSMQ121_RS12520	COG0175	sulfate reduction
SXYLSMQ121_RS12525	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
SXYLSMQ121_RS12525	COG1017	nitric oxide dioxygenase activity
SXYLSMQ121_RS12530	COG1475	DNA binding
SXYLSMQ121_RS12535	COG0626	cystathionine gamma-synthase activity
SXYLSMQ121_RS12540	COG0626	cystathionine gamma-synthase activity
SXYLSMQ121_RS12545	COG0646	methionine synthase
SXYLSMQ121_RS12545	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
SXYLSMQ121_RS12550	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
SXYLSMQ121_RS12560	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
SXYLSMQ121_RS12585	COG0183	Belongs to the thiolase family
SXYLSMQ121_RS12595	COG1960	acyl-CoA dehydrogenase activity
SXYLSMQ121_RS12600	COG0318	PFAM AMP-dependent synthetase and ligase
SXYLSMQ121_RS12610	COG2239	Acts as a magnesium transporter
SXYLSMQ121_RS12615	COG0803	Belongs to the bacterial solute-binding protein 9 family
SXYLSMQ121_RS12620	COG1108	ABC-type Mn2 Zn2 transport systems permease components
SXYLSMQ121_RS12640	COG0561	phosphatase activity
SXYLSMQ121_RS12645	COG0583	DNA-binding transcription factor activity
SXYLSMQ121_RS12650	COG1607	acyl-coa hydrolase
SXYLSMQ121_RS12680	COG0463	Glycosyl transferase, family 2
SXYLSMQ121_RS12680	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
SXYLSMQ121_RS12700	COG0531	amino acid
SXYLSMQ121_RS12705	COG0656	L-ascorbic acid biosynthetic process
SXYLSMQ121_RS12710	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
SXYLSMQ121_RS12730	COG0789	Transcriptional regulator
SXYLSMQ121_RS12745	COG2271	Major facilitator Superfamily
SXYLSMQ121_RS12750	COG1966	Carbon starvation protein
SXYLSMQ121_RS12760	COG0357	Ribosomal RNA small subunit methyltransferase G
SXYLSMQ121_RS12765	COG0445	tRNA wobble uridine modification
SXYLSMQ121_RS12770	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
SXYLSMQ121_RS12775	COG0594	ribonuclease P activity
SXYLSMQ121_RS12795	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
SXYLSMQ121_RS12795	COG0463	Glycosyl transferase, family 2