locus-tag	class	description
JGY87_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
JGY87_RS00010	COG0592	DNA-directed DNA polymerase activity
JGY87_RS00015	COG2501	S4 domain
JGY87_RS00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
JGY87_RS00030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
JGY87_RS00035	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
JGY87_RS00040	COG2986	histidine ammonia-lyase
JGY87_RS00045	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
JGY87_RS00050	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
JGY87_RS00060	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
JGY87_RS00070	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
JGY87_RS00075	COG0359	binds to the 23S rRNA
JGY87_RS00080	COG0305	Participates in initiation and elongation during chromosome replication
JGY87_RS00085	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
JGY87_RS00090	COG1819	glycosyl
JGY87_RS00105	COG0745	RESPONSE REGULATOR receiver
JGY87_RS00110	COG5002	protein histidine kinase activity
JGY87_RS00125	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
JGY87_RS00130	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
JGY87_RS00165	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
JGY87_RS00170	COG1210	Utp--glucose-1-phosphate uridylyltransferase
JGY87_RS00175	COG0438	transferase activity, transferring glycosyl groups
JGY87_RS00190	COG1388	LysM domain
JGY87_RS00195	COG0730	response to heat
JGY87_RS00200	COG1937	Protein conserved in bacteria
JGY87_RS00205	COG2210	Belongs to the sulfur carrier protein TusA family
JGY87_RS00210	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JGY87_RS00220	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
JGY87_RS00225	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
JGY87_RS00305	COG1210	Utp--glucose-1-phosphate uridylyltransferase
JGY87_RS00350	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
JGY87_RS00355	COG0110	maltose O-acetyltransferase activity
JGY87_RS00360	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
JGY87_RS00365	COG1316	TRANSCRIPTIONal
JGY87_RS00370	COG0513	Belongs to the DEAD box helicase family
JGY87_RS00375	COG0494	nUDIX hydrolase
JGY87_RS00395	COG0583	DNA-binding transcription factor activity
JGY87_RS00405	COG3181	Tripartite tricarboxylate transporter family receptor
JGY87_RS00430	COG1349	DNA-binding transcription factor activity
JGY87_RS00435	COG1012	belongs to the aldehyde dehydrogenase family
JGY87_RS00440	COG3718	enzyme involved in inositol metabolism
JGY87_RS00445	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JGY87_RS00450	COG3962	Belongs to the TPP enzyme family
JGY87_RS00455	COG0673	inositol 2-dehydrogenase activity
JGY87_RS00460	COG1082	Xylose isomerase domain protein TIM barrel
JGY87_RS00465	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
JGY87_RS00470	COG0673	inositol 2-dehydrogenase activity
JGY87_RS00475	COG0191	fructose-bisphosphate aldolase activity
JGY87_RS00480	COG1942	4-Oxalocrotonate Tautomerase
JGY87_RS00490	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
JGY87_RS00495	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
JGY87_RS00505	COG1136	(ABC) transporter
JGY87_RS00510	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
JGY87_RS00515	COG2814	Major facilitator Superfamily
JGY87_RS00525	COG0702	epimerase
JGY87_RS00530	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
JGY87_RS00565	COG0415	Belongs to the DNA photolyase family
JGY87_RS00580	COG3711	transcriptional antiterminator
JGY87_RS00585	COG1263	PTS System
JGY87_RS00585	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JGY87_RS00590	COG2723	6-phospho-beta-galactosidase activity
JGY87_RS00605	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
JGY87_RS00610	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
JGY87_RS00635	COG0601	transmembrane transport
JGY87_RS00645	COG0444	Belongs to the ABC transporter superfamily
JGY87_RS00650	COG1124	(ABC) transporter
JGY87_RS00680	COG0583	DNA-binding transcription factor activity
JGY87_RS00685	COG2207	Transcriptional regulator
JGY87_RS00690	COG2211	Major facilitator Superfamily
JGY87_RS00695	COG3250	beta-galactosidase activity
JGY87_RS00705	COG4555	ABC transporter
JGY87_RS00715	COG1476	TRANSCRIPTIONal
JGY87_RS00725	COG0583	DNA-binding transcription factor activity
JGY87_RS00740	COG2814	Major facilitator Superfamily
JGY87_RS00765	COG2814	Major facilitator Superfamily
JGY87_RS00770	COG0463	Glycosyl transferase, family 2
JGY87_RS00790	COG1695	Transcriptional regulator
JGY87_RS00795	COG1028	Short-chain dehydrogenase reductase Sdr
JGY87_RS00800	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
JGY87_RS00805	COG1063	alcohol dehydrogenase
JGY87_RS00815	COG1063	alcohol dehydrogenase
JGY87_RS00820	COG3775	system Galactitol-specific IIC component
JGY87_RS00825	COG3414	Phosphotransferase system galactitol-specific IIB component
JGY87_RS00870	COG3192	ethanolamine utilization protein
JGY87_RS00875	COG1028	Short-chain dehydrogenase reductase Sdr
JGY87_RS00885	COG1012	belongs to the aldehyde dehydrogenase family
JGY87_RS00890	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
JGY87_RS00900	COG2318	DinB family
JGY87_RS00920	COG5002	protein histidine kinase activity
JGY87_RS00925	COG1388	LysM domain
JGY87_RS00930	COG1388	LysM domain
JGY87_RS00935	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
JGY87_RS00945	COG1054	Belongs to the UPF0176 family
JGY87_RS00950	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
JGY87_RS00950	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
JGY87_RS00955	COG1609	Transcriptional regulator
JGY87_RS00965	COG0235	Class ii aldolase
JGY87_RS00970	COG2160	L-arabinose isomerase activity
JGY87_RS00985	COG1131	(ABC) transporter
JGY87_RS00995	COG1695	Transcriptional regulator
JGY87_RS01000	COG3479	Phenolic acid decarboxylase
JGY87_RS01005	COG0477	Major facilitator Superfamily
JGY87_RS01005	COG2814	Major facilitator Superfamily
JGY87_RS01010	COG1070	Carbohydrate kinase
JGY87_RS01015	COG2115	Belongs to the xylose isomerase family
JGY87_RS01020	COG1846	Transcriptional regulator
JGY87_RS01020	COG1940	carbohydrate kinase activity
JGY87_RS01025	COG1511	domain protein
JGY87_RS01040	COG1917	Cupin 2, conserved barrel domain protein
JGY87_RS01040	COG2207	Transcriptional regulator
JGY87_RS01055	COG1070	Carbohydrate kinase
JGY87_RS01060	COG0352	thiamine-phosphate diphosphorylase activity
JGY87_RS01065	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
JGY87_RS01075	COG2022	thiamine diphosphate biosynthetic process
JGY87_RS01080	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
JGY87_RS01085	COG1328	CTP reductase activity
JGY87_RS01090	COG0602	queuosine metabolic process
JGY87_RS01105	COG0431	NADPH-dependent FMN reductase
JGY87_RS01115	COG0346	lactoylglutathione lyase activity
JGY87_RS01120	COG2188	Transcriptional regulator
JGY87_RS01125	COG2084	Dehydrogenase
JGY87_RS01150	COG2311	Membrane
JGY87_RS01165	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
JGY87_RS01170	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
JGY87_RS01175	COG0579	oxidoreductase
JGY87_RS01205	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
JGY87_RS01225	COG2814	Major facilitator Superfamily
JGY87_RS01235	COG0584	glycerophosphoryl diester phosphodiesterase
JGY87_RS01245	COG0668	transmembrane transport
JGY87_RS01250	COG1846	Transcriptional regulator
JGY87_RS01255	COG3961	Belongs to the TPP enzyme family
JGY87_RS01265	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JGY87_RS01305	COG0673	inositol 2-dehydrogenase activity
JGY87_RS01310	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
JGY87_RS01315	COG1691	(AIR) carboxylase
JGY87_RS01320	COG1606	tRNA processing
JGY87_RS01325	COG3875	lactate racemase activity
JGY87_RS01335	COG1929	Belongs to the glycerate kinase type-1 family
JGY87_RS01340	COG3835	regulator
JGY87_RS01345	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
JGY87_RS01345	COG0574	Belongs to the PEP-utilizing enzyme family
JGY87_RS01350	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
JGY87_RS01355	COG2764	glyoxalase bleomycin resistance protein dioxygenase
JGY87_RS01375	COG1476	TRANSCRIPTIONal
JGY87_RS01380	COG2807	transmembrane transport
JGY87_RS01390	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JGY87_RS01395	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
JGY87_RS01400	COG1012	belongs to the aldehyde dehydrogenase family
JGY87_RS01405	COG0531	amino acid
JGY87_RS01425	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
JGY87_RS01430	COG1510	regulation of RNA biosynthetic process
JGY87_RS01435	COG1012	belongs to the aldehyde dehydrogenase family
JGY87_RS01440	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
JGY87_RS01445	COG0463	Glycosyl transferase, family 2
JGY87_RS01445	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
JGY87_RS01455	COG0778	Nitroreductase
JGY87_RS01460	COG2843	Capsule synthesis protein
JGY87_RS01470	COG0477	Major facilitator Superfamily
JGY87_RS01475	COG0531	amino acid
JGY87_RS01480	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
JGY87_RS01485	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
JGY87_RS01490	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
JGY87_RS01495	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
JGY87_RS01500	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
JGY87_RS01510	COG0431	NADPH-dependent FMN reductase
JGY87_RS01525	COG2610	gluconate transmembrane transporter activity
JGY87_RS01530	COG1063	alcohol dehydrogenase
JGY87_RS01535	COG1620	l-lactate permease
JGY87_RS01540	COG2814	Major facilitator Superfamily
JGY87_RS01545	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
JGY87_RS01550	COG2190	(PTS) system
JGY87_RS01550	COG1263	PTS System
JGY87_RS01550	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JGY87_RS01555	COG0363	glucosamine-6-phosphate deaminase activity
JGY87_RS01560	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
JGY87_RS01575	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JGY87_RS01580	COG0765	amino acid transport
JGY87_RS01585	COG1126	abc transporter atp-binding protein
JGY87_RS01590	COG3711	transcriptional antiterminator
JGY87_RS01595	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JGY87_RS01605	COG3037	sugar-specific permease SgaT UlaA
JGY87_RS01610	COG4297	protein containing double-stranded beta helix domain
JGY87_RS01620	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
JGY87_RS01630	COG1464	Belongs to the NlpA lipoprotein family
JGY87_RS01635	COG0039	L-malate dehydrogenase activity
JGY87_RS01655	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JGY87_RS01655	COG3711	transcriptional antiterminator
JGY87_RS01660	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JGY87_RS01660	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JGY87_RS01660	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JGY87_RS01665	COG1482	cell wall glycoprotein biosynthetic process
JGY87_RS01670	COG1940	carbohydrate kinase activity
JGY87_RS01690	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
JGY87_RS01695	COG0626	cystathionine gamma-synthase activity
JGY87_RS01720	COG0829	nickel cation binding
JGY87_RS01725	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
JGY87_RS01730	COG0830	nickel cation binding
JGY87_RS01735	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
JGY87_RS01740	COG0804	urea catabolic process
JGY87_RS01745	COG0832	Belongs to the urease beta subunit family
JGY87_RS01750	COG0831	urea catabolic process
JGY87_RS01755	COG4413	Urea transporter
JGY87_RS01760	COG0747	negative chemotaxis
JGY87_RS01785	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
JGY87_RS01795	COG0531	amino acid
JGY87_RS01815	COG0561	phosphatase activity
JGY87_RS01825	COG0167	dihydroorotate dehydrogenase activity
JGY87_RS01830	COG3001	Fructosamine kinase
JGY87_RS01855	COG0697	spore germination
JGY87_RS01860	COG1113	amino acid transport
JGY87_RS01875	COG3189	MarR family transcriptional regulator
JGY87_RS01890	COG1388	LysM domain
JGY87_RS01895	COG0436	Aminotransferase
JGY87_RS01905	COG2608	mercury ion transmembrane transporter activity
JGY87_RS01910	COG2217	Heavy metal translocating P-type atpase
JGY87_RS01915	COG0659	secondary active sulfate transmembrane transporter activity
JGY87_RS01920	COG1136	(ABC) transporter
JGY87_RS01925	COG0577	efflux transmembrane transporter activity
JGY87_RS01930	COG1028	Short-chain dehydrogenase reductase Sdr
JGY87_RS01940	COG0471	metal ion transport
JGY87_RS01945	COG5505	Protein of unknown function (DUF819)
JGY87_RS01960	COG4336	lyase activity
JGY87_RS01975	COG1012	belongs to the aldehyde dehydrogenase family
JGY87_RS02000	COG1473	amidohydrolase
JGY87_RS02025	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
JGY87_RS02030	COG3425	synthase
JGY87_RS02045	COG3386	PFAM SMP-30 Gluconolaconase
JGY87_RS02050	COG1388	LysM domain
JGY87_RS02050	COG3942	CHAP domain
JGY87_RS02055	COG1757	Na H antiporter
JGY87_RS02060	COG0583	DNA-binding transcription factor activity
JGY87_RS02065	COG1380	Effector of murein hydrolase LrgA
JGY87_RS02075	COG0028	Belongs to the TPP enzyme family
JGY87_RS02080	COG1288	antiporter activity
JGY87_RS02085	COG2190	(PTS) system
JGY87_RS02085	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JGY87_RS02085	COG1263	PTS System
JGY87_RS02100	COG2515	1-aminocyclopropane-1-carboxylate deaminase
JGY87_RS02120	COG0657	acetylesterase activity
JGY87_RS02135	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
JGY87_RS02145	COG2843	Capsule synthesis protein
JGY87_RS02165	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
JGY87_RS02170	COG1063	alcohol dehydrogenase
JGY87_RS02175	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
JGY87_RS02195	COG1129	ABC transporter
JGY87_RS02215	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
JGY87_RS02225	COG3764	Sortase (surface protein transpeptidase)
JGY87_RS02230	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
JGY87_RS02235	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
JGY87_RS02245	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
JGY87_RS02250	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
JGY87_RS02270	COG2249	NAD(P)H dehydrogenase (quinone) activity
JGY87_RS02275	COG0561	phosphatase activity
JGY87_RS02280	COG0778	Nitroreductase
JGY87_RS02285	COG2514	catechol 2,3-dioxygenase activity
JGY87_RS02295	COG1132	(ABC) transporter
JGY87_RS02300	COG1132	(ABC) transporter
JGY87_RS02310	COG0803	Belongs to the bacterial solute-binding protein 9 family
JGY87_RS02315	COG1012	belongs to the aldehyde dehydrogenase family
JGY87_RS02320	COG1846	Transcriptional regulator
JGY87_RS02325	COG0346	lactoylglutathione lyase activity
JGY87_RS02330	COG0346	lactoylglutathione lyase activity
JGY87_RS02335	COG0400	carboxylic ester hydrolase activity
JGY87_RS02345	COG0471	metal ion transport
JGY87_RS02350	COG3949	Membrane
JGY87_RS02360	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
JGY87_RS02365	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
JGY87_RS02370	COG0586	Pfam SNARE associated Golgi protein
JGY87_RS02375	COG2271	Major facilitator Superfamily
JGY87_RS02385	COG3527	Alpha-acetolactate decarboxylase
JGY87_RS02390	COG1289	transmembrane transporter activity
JGY87_RS02405	COG4876	unkown
JGY87_RS02410	COG2357	RelA SpoT domain protein
JGY87_RS02420	COG1802	Transcriptional regulator
JGY87_RS02425	COG1070	Carbohydrate kinase
JGY87_RS02430	COG2610	gluconate transmembrane transporter activity
JGY87_RS02435	COG1028	Short-chain dehydrogenase reductase Sdr
JGY87_RS02440	COG3949	Membrane
JGY87_RS02450	COG2211	Major facilitator Superfamily
JGY87_RS02455	COG3250	beta-galactosidase activity
JGY87_RS02475	COG2211	Major facilitator Superfamily
JGY87_RS02480	COG1904	glucuronate isomerase
JGY87_RS02485	COG1312	Catalyzes the dehydration of D-mannonate
JGY87_RS02500	COG4221	oxidoreductase activity
JGY87_RS02535	COG0107	imidazoleglycerol-phosphate synthase activity
JGY87_RS02540	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
JGY87_RS02545	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
JGY87_RS02550	COG0131	Imidazoleglycerol-phosphate dehydratase
JGY87_RS02555	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
JGY87_RS02560	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
JGY87_RS02565	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
JGY87_RS02575	COG3048	D-serine ammonia-lyase activity
JGY87_RS02580	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
JGY87_RS02585	COG0248	Ppx GppA phosphatase
JGY87_RS02590	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
JGY87_RS02595	COG1028	Short-chain dehydrogenase reductase Sdr
JGY87_RS02600	COG1363	Peptidase, m42
JGY87_RS02610	COG0069	glutamate synthase activity
JGY87_RS02620	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
JGY87_RS02625	COG0390	transport system, permease component
JGY87_RS02630	COG2814	Major facilitator Superfamily
JGY87_RS02635	COG2851	Citrate transporter
JGY87_RS02640	COG0531	amino acid
JGY87_RS02650	COG1309	transcriptional regulator
JGY87_RS02655	COG3246	L-lysine catabolic process to acetate
JGY87_RS02660	COG1250	3-hydroxyacyl-CoA dehydrogenase
JGY87_RS02675	COG1174	glycine betaine transport
JGY87_RS02685	COG1174	glycine betaine transport
JGY87_RS02695	COG1346	cytolysis
JGY87_RS02700	COG1380	Effector of murein hydrolase LrgA
JGY87_RS02705	COG3279	Response regulator of the LytR AlgR family
JGY87_RS02710	COG3275	phosphorelay sensor kinase activity
JGY87_RS02720	COG4187	Peptidase family M20/M25/M40
JGY87_RS02740	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
JGY87_RS02750	COG0706	membrane insertase activity
JGY87_RS02755	COG0025	NhaP-type Na H and K H
JGY87_RS02775	COG2814	Major facilitator Superfamily
JGY87_RS02785	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
JGY87_RS02790	COG1388	LysM domain
JGY87_RS02795	COG0588	phosphoglycerate mutase activity
JGY87_RS02805	COG2814	Major facilitator Superfamily
JGY87_RS02820	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
JGY87_RS02825	COG3443	Belongs to the bacterial solute-binding protein 9 family
JGY87_RS02825	COG0803	Belongs to the bacterial solute-binding protein 9 family
JGY87_RS02830	COG2353	YceI-like domain
JGY87_RS02840	COG1695	Transcriptional regulator
JGY87_RS02860	COG2723	6-phospho-beta-galactosidase activity
JGY87_RS02865	COG2190	(PTS) system
JGY87_RS02865	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JGY87_RS02865	COG1263	PTS System
JGY87_RS02870	COG2188	Transcriptional regulator
JGY87_RS02875	COG2116	formate transmembrane transporter activity
JGY87_RS02880	COG0454	-acetyltransferase
JGY87_RS02895	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
JGY87_RS02900	COG2146	nitrite reductase [NAD(P)H] activity
JGY87_RS02915	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
JGY87_RS02920	COG1140	nitrate reductase beta subunit
JGY87_RS02930	COG2181	nitrate reductase activity
JGY87_RS02940	COG4585	Histidine kinase
JGY87_RS02950	COG2223	nitrite transmembrane transporter activity
JGY87_RS02965	COG1846	Transcriptional regulator
JGY87_RS02990	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JGY87_RS02990	COG1263	PTS System
JGY87_RS03010	COG1283	sodium-dependent phosphate transmembrane transporter activity
JGY87_RS03015	COG1028	Short-chain dehydrogenase reductase Sdr
JGY87_RS03020	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JGY87_RS03025	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JGY87_RS03030	COG1288	antiporter activity
JGY87_RS03035	COG1349	DNA-binding transcription factor activity
JGY87_RS03040	COG1063	alcohol dehydrogenase
JGY87_RS03045	COG2376	Dihydroxyacetone kinase
JGY87_RS03055	COG0698	ribose 5-phosphate isomerase
JGY87_RS03065	COG0492	ferredoxin-NADP+ reductase activity
JGY87_RS03075	COG2814	Major facilitator Superfamily
JGY87_RS03080	COG0604	alcohol dehydrogenase
JGY87_RS03100	COG1620	l-lactate permease
JGY87_RS03105	COG0438	transferase activity, transferring glycosyl groups
JGY87_RS03115	COG3850	Histidine kinase
JGY87_RS03115	COG5002	protein histidine kinase activity
JGY87_RS03120	COG0745	RESPONSE REGULATOR receiver
JGY87_RS03125	COG0577	efflux transmembrane transporter activity
JGY87_RS03130	COG1136	(ABC) transporter
JGY87_RS03145	COG4640	response to antibiotic
JGY87_RS03150	COG2814	Major facilitator Superfamily
JGY87_RS03160	COG1566	PFAM secretion protein HlyD family protein
JGY87_RS03165	COG2814	Major facilitator Superfamily
JGY87_RS03190	COG0598	Magnesium transport protein CorA
JGY87_RS03195	COG1304	FMN binding
JGY87_RS03200	COG0786	glutamate:sodium symporter activity
JGY87_RS03205	COG1757	Na H antiporter
JGY87_RS03210	COG2094	Belongs to the DNA glycosylase MPG family
JGY87_RS03215	COG3152	Membrane
JGY87_RS03220	COG1069	ribulokinase activity
JGY87_RS03225	COG4152	abc transporter atp-binding protein
JGY87_RS03230	COG1668	transmembrane transport
JGY87_RS03235	COG2017	converts alpha-aldose to the beta-anomer
JGY87_RS03240	COG2258	MOSC domain
JGY87_RS03245	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
JGY87_RS03250	COG1266	CAAX protease self-immunity
JGY87_RS03255	COG0010	Belongs to the arginase family
JGY87_RS03260	COG0583	DNA-binding transcription factor activity
JGY87_RS03265	COG3314	Sporulation integral membrane protein YlbJ
JGY87_RS03270	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
JGY87_RS03275	COG1228	amidohydrolase
JGY87_RS03280	COG0659	secondary active sulfate transmembrane transporter activity
JGY87_RS03285	COG1473	amidohydrolase
JGY87_RS03290	COG1028	Short-chain dehydrogenase reductase Sdr
JGY87_RS03295	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
JGY87_RS03315	COG1263	PTS System
JGY87_RS03315	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JGY87_RS03325	COG0385	Bile acid
JGY87_RS03330	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
JGY87_RS03355	COG1113	amino acid transport
JGY87_RS03360	COG1785	Belongs to the alkaline phosphatase family
JGY87_RS03370	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JGY87_RS03370	COG1263	PTS System
JGY87_RS03375	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
JGY87_RS03400	COG1316	TRANSCRIPTIONal
JGY87_RS03405	COG3383	formate dehydrogenase (NAD+) activity
JGY87_RS03435	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
JGY87_RS03440	COG2076	Multidrug Resistance protein
JGY87_RS03445	COG2076	Multidrug Resistance protein
JGY87_RS03450	COG3942	CHAP domain
JGY87_RS03465	COG1757	Na H antiporter
JGY87_RS03470	COG3942	CHAP domain
JGY87_RS03495	COG0765	amino acid transport
JGY87_RS03500	COG0765	amino acid transport
JGY87_RS03505	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JGY87_RS03510	COG1126	abc transporter atp-binding protein
JGY87_RS03515	COG1960	acyl-CoA dehydrogenase activity
JGY87_RS03520	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
JGY87_RS03525	COG1268	BioY protein
JGY87_RS03535	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
JGY87_RS03540	COG1609	Transcriptional regulator
JGY87_RS03545	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
JGY87_RS03550	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
JGY87_RS03555	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
JGY87_RS03560	COG0725	ABC transporter, periplasmic molybdate-binding protein
JGY87_RS03565	COG4149	molybdate abc transporter
JGY87_RS03570	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
JGY87_RS03575	COG1510	regulation of RNA biosynthetic process
JGY87_RS03580	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
JGY87_RS03585	COG0521	Mo-molybdopterin cofactor biosynthetic process
JGY87_RS03590	COG0315	cyclic pyranopterin monophosphate synthase activity
JGY87_RS03615	COG0746	molybdenum cofactor guanylyltransferase activity
JGY87_RS03620	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
JGY87_RS03645	COG2348	transferase activity, transferring amino-acyl groups
JGY87_RS03650	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
JGY87_RS03675	COG4975	Glucose uptake
JGY87_RS03685	COG0551	DNA topoisomerase type I activity
JGY87_RS03685	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
JGY87_RS03690	COG2252	PERMEase
JGY87_RS03700	COG0051	transcription antitermination factor activity, RNA binding
JGY87_RS03705	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
JGY87_RS03710	COG0088	Forms part of the polypeptide exit tunnel
JGY87_RS03715	COG0089	rRNA binding
JGY87_RS03720	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
JGY87_RS03725	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
JGY87_RS03730	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
JGY87_RS03735	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
JGY87_RS03740	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
JGY87_RS03745	COG0255	Belongs to the universal ribosomal protein uL29 family
JGY87_RS03750	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
JGY87_RS03755	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
JGY87_RS03760	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
JGY87_RS03765	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
JGY87_RS03770	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
JGY87_RS03775	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
JGY87_RS03780	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
JGY87_RS03785	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
JGY87_RS03790	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
JGY87_RS03795	COG1841	ribosomal large subunit assembly
JGY87_RS03800	COG0200	Binds to the 23S rRNA
JGY87_RS03805	COG0201	protein transport
JGY87_RS03820	COG0257	Belongs to the bacterial ribosomal protein bL36 family
JGY87_RS03825	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
JGY87_RS03830	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
JGY87_RS03835	COG0202	RNA polymerase activity
JGY87_RS03840	COG0203	ribosomal protein L17
JGY87_RS03845	COG1122	ATPase activity
JGY87_RS03850	COG1122	ATPase activity
JGY87_RS03860	COG0101	tRNA pseudouridine synthase activity
JGY87_RS03865	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
JGY87_RS03870	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
JGY87_RS03880	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JGY87_RS03885	COG2130	NADP-dependent
JGY87_RS03890	COG0604	alcohol dehydrogenase
JGY87_RS03895	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
JGY87_RS03910	COG1302	Protein conserved in bacteria
JGY87_RS03915	COG4264	IucA IucC family
JGY87_RS03920	COG2814	Major facilitator Superfamily
JGY87_RS03925	COG4264	IucA IucC family
JGY87_RS03930	COG3457	Alanine racemase
JGY87_RS03935	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
JGY87_RS03940	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JGY87_RS03945	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JGY87_RS03950	COG3314	Sporulation integral membrane protein YlbJ
JGY87_RS03955	COG2329	Antibiotic biosynthesis monooxygenase
JGY87_RS03965	COG1988	membrane-bound metal-dependent
JGY87_RS03970	COG4284	Utp--glucose-1-phosphate uridylyltransferase
JGY87_RS03975	COG1272	protein, Hemolysin III
JGY87_RS03990	COG0489	protein tyrosine kinase activity
JGY87_RS04045	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
JGY87_RS04055	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
JGY87_RS04060	COG0246	Mannitol dehydrogenase
JGY87_RS04070	COG3711	transcriptional antiterminator
JGY87_RS04075	COG2213	PTS system mannitol-specific
JGY87_RS04090	COG1119	ATPase activity
JGY87_RS04115	COG0640	Transcriptional regulator
JGY87_RS04120	COG0702	epimerase
JGY87_RS04125	COG2186	Transcriptional regulator
JGY87_RS04130	COG1482	cell wall glycoprotein biosynthetic process
JGY87_RS04140	COG2855	membrane
JGY87_RS04155	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JGY87_RS04160	COG0783	Belongs to the Dps family
JGY87_RS04165	COG0813	purine-nucleoside phosphorylase activity
JGY87_RS04170	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
JGY87_RS04175	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
JGY87_RS04180	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
JGY87_RS04190	COG1854	S-ribosylhomocysteine lyase activity
JGY87_RS04210	COG5146	pantothenate kinase activity
JGY87_RS04215	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JGY87_RS04225	COG0504	CTP synthase activity
JGY87_RS04230	COG0191	fructose-bisphosphate aldolase activity
JGY87_RS04235	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
JGY87_RS04245	COG1012	belongs to the aldehyde dehydrogenase family
JGY87_RS04250	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
JGY87_RS04255	COG0254	rRNA binding
JGY87_RS04260	COG1435	thymidine kinase activity
JGY87_RS04265	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
JGY87_RS04270	COG2890	protein-(glutamine-N5) methyltransferase activity
JGY87_RS04275	COG0009	L-threonylcarbamoyladenylate synthase
JGY87_RS04280	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
JGY87_RS04285	COG4475	Protein of unknown function (DUF436)
JGY87_RS04290	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
JGY87_RS04295	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
JGY87_RS04300	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
JGY87_RS04310	COG0356	it plays a direct role in the translocation of protons across the membrane
JGY87_RS04315	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
JGY87_RS04320	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
JGY87_RS04325	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
JGY87_RS04330	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
JGY87_RS04335	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
JGY87_RS04340	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
JGY87_RS04345	COG0355	proton-transporting ATP synthase activity, rotational mechanism
JGY87_RS04355	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
JGY87_RS04360	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
JGY87_RS04370	COG0629	single-stranded DNA binding
JGY87_RS04375	COG1388	LysM domain
JGY87_RS04380	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
JGY87_RS04390	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
JGY87_RS04395	COG0352	thiamine-phosphate diphosphorylase activity
JGY87_RS04400	COG0706	membrane insertase activity
JGY87_RS04405	COG1418	mRNA catabolic process
JGY87_RS04415	COG1937	Protein conserved in bacteria
JGY87_RS04430	COG0772	Belongs to the SEDS family
JGY87_RS04435	COG1181	Belongs to the D-alanine--D-alanine ligase family
JGY87_RS04440	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
JGY87_RS04445	COG0513	Belongs to the DEAD box helicase family
JGY87_RS04455	COG3428	Bacterial PH domain
JGY87_RS04470	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
JGY87_RS04480	COG2337	Toxic component of a toxin-antitoxin (TA) module
JGY87_RS04485	COG2208	phosphoserine phosphatase activity
JGY87_RS04500	COG1191	sigma factor activity
JGY87_RS04505	COG2183	response to ionizing radiation
JGY87_RS04510	COG3091	SprT-like family
JGY87_RS04540	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
JGY87_RS04545	COG0066	3-isopropylmalate dehydratase activity
JGY87_RS04550	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
JGY87_RS04555	COG0473	3-isopropylmalate dehydrogenase activity
JGY87_RS04560	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
JGY87_RS04565	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
JGY87_RS04570	COG0440	acetolactate synthase activity
JGY87_RS04575	COG0028	Belongs to the TPP enzyme family
JGY87_RS04580	COG0129	dihydroxy-acid dehydratase activity
JGY87_RS04585	COG0802	atpase or kinase
JGY87_RS04590	COG1214	PFAM Peptidase M22, glycoprotease
JGY87_RS04595	COG0456	acetyltransferase
JGY87_RS04600	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
JGY87_RS04610	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
JGY87_RS04615	COG0488	(ABC) transporter
JGY87_RS04620	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
JGY87_RS04625	COG2391	methyltransferase activity
JGY87_RS04630	COG0425	Belongs to the sulfur carrier protein TusA family
JGY87_RS04635	COG1609	Transcriptional regulator
JGY87_RS04640	COG1621	beta-fructofuranosidase activity
JGY87_RS04645	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JGY87_RS04650	COG3279	Response regulator of the LytR AlgR family
JGY87_RS04655	COG3290	protein histidine kinase activity
JGY87_RS04665	COG4512	PFAM Accessory gene regulator B
JGY87_RS04670	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
JGY87_RS04690	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
JGY87_RS04695	COG0459	protein refolding
JGY87_RS04720	COG1725	Transcriptional regulator
JGY87_RS04735	COG1131	(ABC) transporter
JGY87_RS04780	COG2706	6-phosphogluconolactonase activity
JGY87_RS04785	COG1012	belongs to the aldehyde dehydrogenase family
JGY87_RS04790	COG1227	inorganic diphosphatase activity
JGY87_RS04795	COG1335	isochorismatase
JGY87_RS04805	COG0471	metal ion transport
JGY87_RS04810	COG0077	Prephenate dehydratase
JGY87_RS04820	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
JGY87_RS04825	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
JGY87_RS04830	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
JGY87_RS04840	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
JGY87_RS04845	COG4496	protein, YerC YecD
JGY87_RS04850	COG1876	peptidase activity
JGY87_RS04855	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
JGY87_RS04865	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
JGY87_RS04870	COG4851	CamS sex pheromone cAM373 precursor
JGY87_RS04875	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
JGY87_RS04880	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
JGY87_RS04885	COG0154	amidase activity
JGY87_RS04890	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
JGY87_RS04895	COG1597	lipid kinase activity
JGY87_RS04900	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
JGY87_RS04910	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
JGY87_RS04920	COG1528	Iron-storage protein
JGY87_RS04935	COG4129	membrane
JGY87_RS04940	COG0024	Methionine aminopeptidase
JGY87_RS04955	COG4585	Histidine kinase
JGY87_RS04960	COG2197	response regulator
JGY87_RS04965	COG1295	ribonuclease BN
JGY87_RS04975	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
JGY87_RS04980	COG4840	Belongs to the UPF0435 family
JGY87_RS04985	COG2309	aminopeptidase activity
JGY87_RS04990	COG1607	acyl-coa hydrolase
JGY87_RS04995	COG0535	radical SAM domain protein
JGY87_RS05005	COG0693	protein deglycase activity
JGY87_RS05010	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
JGY87_RS05015	COG2137	regulation of response to DNA damage stimulus
JGY87_RS05025	COG1134	teichoic acid transport
JGY87_RS05035	COG1988	membrane-bound metal-dependent
JGY87_RS05045	COG3557	Belongs to the UPF0374 family
JGY87_RS05055	COG4129	membrane
JGY87_RS05060	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
JGY87_RS05065	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
JGY87_RS05070	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
JGY87_RS05075	COG0735	belongs to the Fur family
JGY87_RS05225	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
JGY87_RS05240	COG0765	amino acid transport
JGY87_RS05245	COG1126	abc transporter atp-binding protein
JGY87_RS05250	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
JGY87_RS05260	COG0363	glucosamine-6-phosphate deaminase activity
JGY87_RS05275	COG0114	fumarate hydratase activity
JGY87_RS05280	COG0564	pseudouridine synthase activity
JGY87_RS05285	COG2203	Gaf domain
JGY87_RS05285	COG4585	Histidine kinase
JGY87_RS05290	COG2197	response regulator
JGY87_RS05300	COG0772	Belongs to the SEDS family
JGY87_RS05305	COG1316	TRANSCRIPTIONal
JGY87_RS05310	COG0730	response to heat
JGY87_RS05320	COG1682	transport, permease protein
JGY87_RS05335	COG0788	formyltetrahydrofolate deformylase activity
JGY87_RS05345	COG4399	Belongs to the UPF0754 family
JGY87_RS05350	COG3679	Belongs to the UPF0342 family
JGY87_RS05355	COG0420	3'-5' exonuclease activity
JGY87_RS05360	COG4717	serine-type aminopeptidase activity
JGY87_RS05365	COG3481	metal-dependent phosphohydrolase, HD sub domain
JGY87_RS05370	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
JGY87_RS05385	COG0537	adenosine 5'-monophosphoramidase activity
JGY87_RS05390	COG1131	(ABC) transporter
JGY87_RS05395	COG4473	ABC transporter
JGY87_RS05405	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
JGY87_RS05410	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
JGY87_RS05415	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
JGY87_RS05420	COG3545	Serine hydrolase
JGY87_RS05510	COG4824	toxin secretion phage lysis holin
JGY87_RS05530	COG1388	LysM domain
JGY87_RS05530	COG5632	N-Acetylmuramoyl-L-alanine amidase
JGY87_RS05555	COG1028	Short-chain dehydrogenase reductase Sdr
JGY87_RS05575	COG0300	oxidoreductase activity
JGY87_RS05605	COG0318	PFAM AMP-dependent synthetase and ligase
JGY87_RS05615	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
JGY87_RS05625	COG1506	peptidase
JGY87_RS05630	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
JGY87_RS05635	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
JGY87_RS05645	COG0656	L-ascorbic acid biosynthetic process
JGY87_RS05650	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
JGY87_RS05655	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
JGY87_RS05665	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
JGY87_RS05685	COG1595	DNA-templated transcription, initiation
JGY87_RS05695	COG3266	domain, Protein
JGY87_RS05695	COG4193	domain, Protein
JGY87_RS05695	COG5632	N-Acetylmuramoyl-L-alanine amidase
JGY87_RS05710	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
JGY87_RS05710	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
JGY87_RS05715	COG0307	riboflavin synthase, alpha
JGY87_RS05720	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
JGY87_RS05720	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
JGY87_RS05725	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
JGY87_RS05735	COG2267	carboxylic ester hydrolase activity
JGY87_RS05740	COG0039	L-malate dehydrogenase activity
JGY87_RS05750	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
JGY87_RS05755	COG1242	4 iron, 4 sulfur cluster binding
JGY87_RS05760	COG2814	Major facilitator Superfamily
JGY87_RS05765	COG0495	leucyl-tRNA aminoacylation
JGY87_RS05775	COG2081	HI0933 family
JGY87_RS05780	COG2244	polysaccharide biosynthetic process
JGY87_RS05785	COG1187	pseudouridine synthase activity
JGY87_RS05795	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
JGY87_RS05800	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
JGY87_RS05805	COG0510	thiamine kinase activity
JGY87_RS05810	COG0220	tRNA (guanine-N7-)-methyltransferase activity
JGY87_RS05815	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JGY87_RS05825	COG1363	Peptidase, m42
JGY87_RS05830	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JGY87_RS05835	COG4848	Belongs to the UPF0354 family
JGY87_RS05840	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JGY87_RS05845	COG1674	ftsk spoiiie
JGY87_RS05850	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
JGY87_RS05855	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
JGY87_RS05865	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
JGY87_RS05865	COG1605	Chorismate mutase
JGY87_RS05870	COG1609	Transcriptional regulator
JGY87_RS05875	COG0123	including yeast histone deacetylase and acetoin utilization protein
JGY87_RS05880	COG0454	-acetyltransferase
JGY87_RS05885	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
JGY87_RS05900	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
JGY87_RS05905	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JGY87_RS05910	COG0204	Acyl-transferase
JGY87_RS05925	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
JGY87_RS05930	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
JGY87_RS05935	COG1764	response to oxidative stress
JGY87_RS05940	COG0584	glycerophosphoryl diester phosphodiesterase
JGY87_RS05945	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JGY87_RS05950	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
JGY87_RS05955	COG1956	GAF domain-containing protein
JGY87_RS05960	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
JGY87_RS05965	COG1104	cysteine desulfurase activity
JGY87_RS05970	COG0301	tRNA thio-modification
JGY87_RS05980	COG0616	signal peptide processing
JGY87_RS05985	COG1714	RDD family
JGY87_RS05990	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
JGY87_RS05995	COG0827	DNA restriction-modification system
JGY87_RS06000	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
JGY87_RS06010	COG0589	response to stress
JGY87_RS06015	COG0686	Belongs to the AlaDH PNT family
JGY87_RS06020	COG3142	Participates in the control of copper homeostasis
JGY87_RS06025	COG0006	proline dipeptidase activity
JGY87_RS06030	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
JGY87_RS06040	COG4109	DRTGG domain
JGY87_RS06045	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
JGY87_RS06050	COG0587	DNA-directed DNA polymerase activity
JGY87_RS06055	COG0281	malic enzyme
JGY87_RS06060	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
JGY87_RS06065	COG0825	malonyl-CoA metabolic process
JGY87_RS06070	COG0205	6-phosphofructokinase activity
JGY87_RS06075	COG0469	pyruvate kinase activity
JGY87_RS06080	COG1113	amino acid transport
JGY87_RS06085	COG0372	Belongs to the citrate synthase family
JGY87_RS06090	COG0538	isocitrate dehydrogenase activity
JGY87_RS06095	COG0745	RESPONSE REGULATOR receiver
JGY87_RS06100	COG5002	protein histidine kinase activity
JGY87_RS06105	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
JGY87_RS06105	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
JGY87_RS06115	COG0237	dephospho-CoA kinase activity
JGY87_RS06120	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
JGY87_RS06125	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
JGY87_RS06135	COG1484	DNA-dependent DNA replication
JGY87_RS06140	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
JGY87_RS06145	COG0833	amino acid
JGY87_RS06150	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
JGY87_RS06155	COG0291	Belongs to the bacterial ribosomal protein bL35 family
JGY87_RS06160	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
JGY87_RS06165	COG4112	unkown
JGY87_RS06175	COG0544	peptidyl-prolyl cis-trans isomerase activity
JGY87_RS06180	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
JGY87_RS06185	COG0218	Necessary for normal cell division and for the maintenance of normal septation
JGY87_RS06190	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
JGY87_RS06195	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
JGY87_RS06200	COG0181	hydroxymethylbilane synthase activity
JGY87_RS06210	COG0113	porphobilinogen synthase activity
JGY87_RS06215	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
JGY87_RS06225	COG2818	Glycosylase
JGY87_RS06230	COG0525	valine-tRNA ligase activity
JGY87_RS06235	COG0285	dihydrofolate synthase activity
JGY87_RS06250	COG2003	Belongs to the UPF0758 family
JGY87_RS06285	COG0261	This protein binds to 23S rRNA in the presence of protein L20
JGY87_RS06290	COG2868	ribosomal protein
JGY87_RS06295	COG0211	Belongs to the bacterial ribosomal protein bL27 family
JGY87_RS06300	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
JGY87_RS06305	COG4492	Belongs to the UPF0735 family
JGY87_RS06310	COG0632	four-way junction helicase activity
JGY87_RS06315	COG2255	four-way junction helicase activity
JGY87_RS06320	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
JGY87_RS06325	COG0343	queuine tRNA-ribosyltransferase activity
JGY87_RS06330	COG1862	Preprotein translocase
JGY87_RS06335	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
JGY87_RS06335	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
JGY87_RS06340	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
JGY87_RS06340	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
JGY87_RS06350	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
JGY87_RS06355	COG1490	D-aminoacyl-tRNA deacylase activity
JGY87_RS06360	COG0860	N-Acetylmuramoyl-L-alanine amidase
JGY87_RS06365	COG0124	histidyl-tRNA synthetase
JGY87_RS06370	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
JGY87_RS06380	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
JGY87_RS06385	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
JGY87_RS06390	COG1959	2 iron, 2 sulfur cluster binding
JGY87_RS06405	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JGY87_RS06410	COG0488	(ABC) transporter
JGY87_RS06415	COG1104	cysteine desulfurase activity
JGY87_RS06420	COG0482	sulfurtransferase activity
JGY87_RS06430	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
JGY87_RS06435	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
JGY87_RS06440	COG4472	Bacterial protein of unknown function (DUF965)
JGY87_RS06445	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
JGY87_RS06450	COG3906	Belongs to the UPF0473 family
JGY87_RS06455	COG4122	O-methyltransferase activity
JGY87_RS06460	COG0826	peptidase U32
JGY87_RS06465	COG0826	peptidase U32
JGY87_RS06470	COG0572	uridine kinase
JGY87_RS06475	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
JGY87_RS06480	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
JGY87_RS06485	COG1984	allophanate hydrolase subunit 2
JGY87_RS06490	COG0511	ligase activity, forming carbon-carbon bonds
JGY87_RS06495	COG0439	Biotin carboxylase
JGY87_RS06500	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
JGY87_RS06505	COG1914	H( )-stimulated, divalent metal cation uptake system
JGY87_RS06510	COG0730	response to heat
JGY87_RS06515	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
JGY87_RS06520	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
JGY87_RS06525	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
JGY87_RS06530	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
JGY87_RS06535	COG1534	Rna-binding protein
JGY87_RS06540	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
JGY87_RS06545	COG1713	HD superfamily hydrolase involved in NAD metabolism
JGY87_RS06550	COG0799	negative regulation of ribosome biogenesis
JGY87_RS06555	COG2226	methyltransferase
JGY87_RS06560	COG1555	photosystem II stabilization
JGY87_RS06560	COG1596	polysaccharide export
JGY87_RS06565	COG2131	deaminase
JGY87_RS06575	COG0658	competence protein
JGY87_RS06575	COG2333	competence protein COMEC
JGY87_RS06580	COG1466	dna polymerase III delta subunit
JGY87_RS06585	COG0268	Binds directly to 16S ribosomal RNA
JGY87_RS06590	COG0481	GTPase activity
JGY87_RS06595	COG0635	Involved in the biosynthesis of porphyrin-containing compound
JGY87_RS06600	COG1420	regulation of RNA biosynthetic process
JGY87_RS06605	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
JGY87_RS06610	COG0443	Heat shock 70 kDa protein
JGY87_RS06615	COG0484	heat shock protein binding
JGY87_RS06620	COG2264	protein methyltransferase activity
JGY87_RS06625	COG1385	rRNA (uridine-N3-)-methyltransferase activity
JGY87_RS06630	COG0828	Belongs to the bacterial ribosomal protein bS21 family
JGY87_RS06635	COG1030	water channel activity
JGY87_RS06640	COG4864	UPF0365 protein
JGY87_RS06650	COG1702	phosphate starvation-inducible protein PhoH
JGY87_RS06655	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
JGY87_RS06660	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
JGY87_RS06665	COG0295	cytidine deaminase activity
JGY87_RS06670	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
JGY87_RS06675	COG1381	Involved in DNA repair and RecF pathway recombination
JGY87_RS06680	COG0423	glycine-tRNA ligase activity
JGY87_RS06685	COG0517	IMP dehydrogenase activity
JGY87_RS06690	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
JGY87_RS06700	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
JGY87_RS06705	COG2384	SAM-dependent methyltransferase
JGY87_RS06715	COG0513	Belongs to the DEAD box helicase family
JGY87_RS06720	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
JGY87_RS06725	COG1121	(ABC) transporter
JGY87_RS06730	COG1108	ABC-type Mn2 Zn2 transport systems permease components
JGY87_RS06740	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
JGY87_RS06745	COG0768	penicillin binding
JGY87_RS06750	COG0267	Belongs to the bacterial ribosomal protein bL33 family
JGY87_RS06755	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
JGY87_RS06760	COG0457	Tetratricopeptide repeat
JGY87_RS06760	COG0705	Rhomboid family
JGY87_RS06765	COG4483	Protein conserved in bacteria
JGY87_RS06770	COG1940	carbohydrate kinase activity
JGY87_RS06775	COG0011	TIGRFAM Protein of
JGY87_RS06780	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JGY87_RS06785	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
JGY87_RS06815	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
JGY87_RS06820	COG0404	The glycine cleavage system catalyzes the degradation of glycine
JGY87_RS06825	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
JGY87_RS06830	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
JGY87_RS06835	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
JGY87_RS06840	COG0095	Lipoate-protein ligase
JGY87_RS06855	COG0006	proline dipeptidase activity
JGY87_RS06860	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
JGY87_RS06865	COG0511	ligase activity, forming carbon-carbon bonds
JGY87_RS06870	COG0439	Biotin carboxylase
JGY87_RS06875	COG1302	Protein conserved in bacteria
JGY87_RS06880	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
JGY87_RS06885	COG1570	exodeoxyribonuclease VII activity
JGY87_RS06890	COG1722	exodeoxyribonuclease VII activity
JGY87_RS06900	COG1438	arginine binding
JGY87_RS06905	COG0497	DNA recombination
JGY87_RS06910	COG0280	phosphate acetyltransferase
JGY87_RS06915	COG3426	butyrate kinase activity
JGY87_RS06920	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
JGY87_RS06925	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
JGY87_RS06930	COG0022	dehydrogenase e1 component
JGY87_RS06935	COG0508	dehydrogenase complex catalyzes the overall conversion of
JGY87_RS06945	COG4129	membrane
JGY87_RS06955	COG2195	Cleaves the N-terminal amino acid of tripeptides
JGY87_RS06965	COG1609	Transcriptional regulator
JGY87_RS06970	COG0366	Alpha amylase catalytic
JGY87_RS06980	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
JGY87_RS06985	COG1234	tRNA 3'-trailer cleavage
JGY87_RS06990	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
JGY87_RS07000	COG0667	Aldo Keto reductase
JGY87_RS07005	COG0494	nUDIX hydrolase
JGY87_RS07010	COG0735	belongs to the Fur family
JGY87_RS07015	COG4974	Belongs to the 'phage' integrase family
JGY87_RS07025	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
JGY87_RS07030	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
JGY87_RS07035	COG1187	pseudouridine synthase activity
JGY87_RS07040	COG0745	RESPONSE REGULATOR receiver
JGY87_RS07055	COG1141	Ferredoxin
JGY87_RS07065	COG0514	ATP-dependent DNA helicase (RecQ)
JGY87_RS07070	COG1388	LysM domain
JGY87_RS07075	COG0492	ferredoxin-NADP+ reductase activity
JGY87_RS07085	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
JGY87_RS07090	COG0539	negative regulation of cytoplasmic translation
JGY87_RS07095	COG1160	GTP binding
JGY87_RS07100	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
JGY87_RS07115	COG2226	methyltransferase
JGY87_RS07120	COG0142	geranyltranstransferase activity
JGY87_RS07125	COG0105	UTP biosynthetic process
JGY87_RS07130	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
JGY87_RS07135	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
JGY87_RS07140	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
JGY87_RS07150	COG5582	Belongs to the UPF0302 family
JGY87_RS07155	COG4347	Protein of unknown function (DUF1405)
JGY87_RS07160	COG2738	Putative neutral zinc metallopeptidase
JGY87_RS07165	COG1694	Mazg nucleotide pyrophosphohydrolase
JGY87_RS07170	COG0438	transferase activity, transferring glycosyl groups
JGY87_RS07175	COG0617	tRNA 3'-terminal CCA addition
JGY87_RS07185	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
JGY87_RS07185	COG1199	ATP-dependent helicase activity
JGY87_RS07190	COG0017	Asparaginyl-tRNA synthetase
JGY87_RS07195	COG3935	DnaD domain protein
JGY87_RS07200	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
JGY87_RS07210	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
JGY87_RS07210	COG4499	WXG100 protein secretion system (Wss), protein YukC
JGY87_RS07215	COG3331	DNA recombination
JGY87_RS07225	COG4474	Belongs to the UPF0398 family
JGY87_RS07240	COG0116	Belongs to the methyltransferase superfamily
JGY87_RS07245	COG2962	Rard protein
JGY87_RS07255	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
JGY87_RS07260	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
JGY87_RS07270	COG3545	Serine hydrolase
JGY87_RS07275	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
JGY87_RS07285	COG1413	lyase activity
JGY87_RS07290	COG1413	lyase activity
JGY87_RS07300	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
JGY87_RS07320	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
JGY87_RS07330	COG4479	Belongs to the UPF0346 family
JGY87_RS07335	COG0793	Belongs to the peptidase S41A family
JGY87_RS07345	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
JGY87_RS07350	COG0671	phosphoesterase, PA-phosphatase related
JGY87_RS07355	COG0745	RESPONSE REGULATOR receiver
JGY87_RS07360	COG5002	protein histidine kinase activity
JGY87_RS07365	COG0567	Dehydrogenase, E1 component
JGY87_RS07370	COG0508	dehydrogenase complex catalyzes the overall conversion of
JGY87_RS07380	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
JGY87_RS07390	COG2207	Transcriptional regulator
JGY87_RS07390	COG1917	Cupin 2, conserved barrel domain protein
JGY87_RS07415	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
JGY87_RS07420	COG1121	(ABC) transporter
JGY87_RS07445	COG0714	Associated with various cellular activities
JGY87_RS07450	COG4548	von Willebrand factor, type A
JGY87_RS07455	COG1114	Component of the transport system for branched-chain amino acids
JGY87_RS07460	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
JGY87_RS07465	COG3853	Toxic anion resistance protein (TelA)
JGY87_RS07475	COG1254	Belongs to the acylphosphatase family
JGY87_RS07485	COG1278	Cold shock
JGY87_RS07500	COG1473	amidohydrolase
JGY87_RS07510	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
JGY87_RS07515	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
JGY87_RS07520	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
JGY87_RS07525	COG0527	aspartate kinase activity
JGY87_RS07535	COG0488	(ABC) transporter
JGY87_RS07540	COG2996	Protein conserved in bacteria
JGY87_RS07545	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
JGY87_RS07550	COG0573	inorganic phosphate transmembrane transporter activity
JGY87_RS07555	COG0581	inorganic phosphate transmembrane transporter activity
JGY87_RS07560	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
JGY87_RS07565	COG0704	Plays a role in the regulation of phosphate uptake
JGY87_RS07570	COG1164	Oligoendopeptidase f
JGY87_RS07580	COG4607	ABC-type enterochelin transport system periplasmic component
JGY87_RS07595	COG2348	transferase activity, transferring amino-acyl groups
JGY87_RS07605	COG0159	tryptophan synthase activity
JGY87_RS07610	COG0133	tryptophan synthase activity
JGY87_RS07620	COG0134	indole-3-glycerol-phosphate synthase activity
JGY87_RS07625	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
JGY87_RS07630	COG0512	Glutamine amidotransferase of anthranilate synthase
JGY87_RS07635	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
JGY87_RS07650	COG0438	transferase activity, transferring glycosyl groups
JGY87_RS07655	COG0584	glycerophosphoryl diester phosphodiesterase
JGY87_RS07665	COG1363	Peptidase, m42
JGY87_RS07675	COG0287	Prephenate dehydrogenase
JGY87_RS07680	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
JGY87_RS07685	COG1942	4-Oxalocrotonate Tautomerase
JGY87_RS07700	COG1879	ABC-type sugar transport system periplasmic component
JGY87_RS07705	COG1172	Belongs to the binding-protein-dependent transport system permease family
JGY87_RS07710	COG1129	ABC transporter
JGY87_RS07715	COG1869	D-ribose catabolic process
JGY87_RS07720	COG1609	Transcriptional regulator
JGY87_RS07730	COG0392	lysyltransferase activity
JGY87_RS07730	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
JGY87_RS07735	COG0628	permease
JGY87_RS07745	COG3711	transcriptional antiterminator
JGY87_RS07750	COG1115	amino acid carrier protein
JGY87_RS07755	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
JGY87_RS07765	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
JGY87_RS07770	COG4841	protein insertion into membrane
JGY87_RS07775	COG0824	Thioesterase
JGY87_RS07780	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
JGY87_RS07785	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
JGY87_RS07790	COG1970	mechanosensitive ion channel activity
JGY87_RS07795	COG0419	ATPase involved in DNA repair
JGY87_RS07800	COG0420	3'-5' exonuclease activity
JGY87_RS07805	COG4846	Membrane protein involved in cytochrome C biogenesis
JGY87_RS07815	COG3763	UPF0154 protein
JGY87_RS07835	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
JGY87_RS07845	COG0516	GMP reductase activity
JGY87_RS07850	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
JGY87_RS07855	COG0267	Belongs to the bacterial ribosomal protein bL33 family
JGY87_RS07860	COG0753	catalase activity
JGY87_RS07865	COG0833	amino acid
JGY87_RS07875	COG0561	phosphatase activity
JGY87_RS07880	COG0083	homoserine kinase activity
JGY87_RS07885	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
JGY87_RS07890	COG0460	homoserine dehydrogenase
JGY87_RS07895	COG0527	aspartate kinase activity
JGY87_RS07930	COG2808	Putative FMN-binding domain
JGY87_RS07935	COG1764	response to oxidative stress
JGY87_RS07945	COG0789	Transcriptional regulator
JGY87_RS07950	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
JGY87_RS07955	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
JGY87_RS07960	COG0386	Belongs to the glutathione peroxidase family
JGY87_RS07965	COG1923	regulation of RNA biosynthetic process
JGY87_RS07970	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
JGY87_RS07980	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
JGY87_RS07985	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
JGY87_RS07990	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
JGY87_RS08005	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
JGY87_RS08010	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
JGY87_RS08020	COG4550	Control of competence regulator ComK, YlbF/YmcA
JGY87_RS08025	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
JGY87_RS08040	COG1959	2 iron, 2 sulfur cluster binding
JGY87_RS08045	COG4195	phage-related replication protein
JGY87_RS08055	COG1013	pyruvate-flavodoxin oxidoreductase activity
JGY87_RS08060	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
JGY87_RS08060	COG0674	pyruvate-flavodoxin oxidoreductase activity
JGY87_RS08065	COG1692	metallophosphoesterase
JGY87_RS08075	COG1418	mRNA catabolic process
JGY87_RS08080	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
JGY87_RS08085	COG1546	Belongs to the CinA family
JGY87_RS08085	COG1058	Belongs to the CinA family
JGY87_RS08105	COG0300	oxidoreductase activity
JGY87_RS08110	COG0612	Peptidase, M16
JGY87_RS08115	COG0612	Peptidase, M16
JGY87_RS08120	COG2188	Transcriptional regulator
JGY87_RS08125	COG1674	ftsk spoiiie
JGY87_RS08130	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
JGY87_RS08135	COG1185	polyribonucleotide nucleotidyltransferase activity
JGY87_RS08140	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
JGY87_RS08145	COG0196	riboflavin kinase activity
JGY87_RS08150	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
JGY87_RS08155	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
JGY87_RS08170	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
JGY87_RS08175	COG1358	cellular component organization or biogenesis
JGY87_RS08180	COG2740	Nucleic-acid-binding protein implicated in transcription termination
JGY87_RS08185	COG0195	Participates in both transcription termination and antitermination
JGY87_RS08190	COG0779	Required for maturation of 30S ribosomal subunits
JGY87_RS08195	COG2176	DNA-directed DNA polymerase activity
JGY87_RS08200	COG0442	prolyl-tRNA aminoacylation
JGY87_RS08210	COG4589	Belongs to the CDS family
JGY87_RS08215	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
JGY87_RS08220	COG0233	cytoplasmic translational termination
JGY87_RS08225	COG0528	UMP kinase activity
JGY87_RS08230	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
JGY87_RS08235	COG0052	Belongs to the universal ribosomal protein uS2 family
JGY87_RS08240	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
JGY87_RS08245	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
JGY87_RS08250	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
JGY87_RS08255	COG4974	Belongs to the 'phage' integrase family
JGY87_RS08260	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
JGY87_RS08265	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
JGY87_RS08270	COG0758	DNA mediated transformation
JGY87_RS08280	COG0045	succinate-CoA ligase (ADP-forming) activity
JGY87_RS08285	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
JGY87_RS08295	COG4485	Bacterial membrane protein, YfhO
JGY87_RS08305	COG0335	large ribosomal subunit rRNA binding
JGY87_RS08310	COG0336	Belongs to the RNA methyltransferase TrmD family
JGY87_RS08315	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
JGY87_RS08320	COG0228	four-way junction DNA binding
JGY87_RS08325	COG1028	Short-chain dehydrogenase reductase Sdr
JGY87_RS08330	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JGY87_RS08335	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
JGY87_RS08340	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
JGY87_RS08345	COG0552	protein localization to endoplasmic reticulum
JGY87_RS08350	COG1196	nuclear chromosome segregation
JGY87_RS08355	COG0571	ribonuclease III activity
JGY87_RS08360	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
JGY87_RS08375	COG0416	fatty acid biosynthetic process
JGY87_RS08380	COG1349	DNA-binding transcription factor activity
JGY87_RS08390	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
JGY87_RS08395	COG1760	l-serine dehydratase
JGY87_RS08400	COG1760	l-serine dehydratase
JGY87_RS08405	COG1461	Dihydroxyacetone kinase
JGY87_RS08410	COG1302	Protein conserved in bacteria
JGY87_RS08415	COG0227	Belongs to the bacterial ribosomal protein bL28 family
JGY87_RS08420	COG1564	THIamine pyrophosphokinase
JGY87_RS08425	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
JGY87_RS08430	COG1162	GTPase activity
JGY87_RS08445	COG0820	rRNA (adenine-C2-)-methyltransferase activity
JGY87_RS08450	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
JGY87_RS08450	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
JGY87_RS08455	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
JGY87_RS08460	COG0242	peptide deformylase activity
JGY87_RS08475	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
JGY87_RS08480	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
JGY87_RS08485	COG1758	RNA polymerase activity
JGY87_RS08490	COG0194	GDP metabolic process
JGY87_RS08495	COG1293	RNA-binding protein homologous to eukaryotic snRNP
JGY87_RS08505	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
JGY87_RS08515	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
JGY87_RS08520	COG0284	orotidine-5'-phosphate decarboxylase activity
JGY87_RS08525	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
JGY87_RS08530	COG0505	Belongs to the CarA family
JGY87_RS08540	COG0540	Belongs to the ATCase OTCase family
JGY87_RS08550	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
JGY87_RS08555	COG0564	pseudouridine synthase activity
JGY87_RS08560	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
JGY87_RS08570	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
JGY87_RS08575	COG3599	regulation of cell shape
JGY87_RS08585	COG0762	integral membrane protein
JGY87_RS08590	COG1799	cell septum assembly
JGY87_RS08595	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
JGY87_RS08600	COG1496	oxidoreductase activity
JGY87_RS08605	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
JGY87_RS08610	COG0849	cell division
JGY87_RS08620	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
JGY87_RS08625	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
JGY87_RS08630	COG0768	penicillin binding
JGY87_RS08635	COG4839	cell division protein FtsL
JGY87_RS08640	COG0275	rRNA processing
JGY87_RS08645	COG2001	Belongs to the MraZ family
JGY87_RS08650	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
JGY87_RS08655	COG0454	-acetyltransferase
JGY87_RS08660	COG1011	Hydrolase
JGY87_RS08735	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
JGY87_RS08740	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
JGY87_RS08745	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
JGY87_RS08750	COG1053	succinate dehydrogenase
JGY87_RS08755	COG2009	succinate dehydrogenase
JGY87_RS08760	COG0322	excinuclease ABC activity
JGY87_RS08765	COG3118	belongs to the thioredoxin family
JGY87_RS08770	COG1193	negative regulation of DNA recombination
JGY87_RS08775	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
JGY87_RS08775	COG1796	DNA polymerase
JGY87_RS08785	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
JGY87_RS08790	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
JGY87_RS08795	COG0072	phenylalanine-tRNA ligase activity
JGY87_RS08800	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
JGY87_RS08805	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
JGY87_RS08815	COG0333	Belongs to the bacterial ribosomal protein bL32 family
JGY87_RS08825	COG1323	Belongs to the UPF0348 family
JGY87_RS08830	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
JGY87_RS08835	COG0742	ribosomal rna small subunit methyltransferase
JGY87_RS08845	COG4471	UPF0298 protein
JGY87_RS08850	COG0584	glycerophosphoryl diester phosphodiesterase
JGY87_RS08855	COG3679	Belongs to the UPF0342 family
JGY87_RS08865	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
JGY87_RS08875	COG0109	protoheme IX farnesyltransferase activity
JGY87_RS08880	COG1612	heme a metabolic process
JGY87_RS08890	COG0772	Belongs to the SEDS family
JGY87_RS08895	COG4838	Belongs to the UPF0358 family
JGY87_RS08900	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
JGY87_RS08905	COG4896	Protein conserved in bacteria
JGY87_RS08910	COG1217	gtp-binding protein TYPA
JGY87_RS08920	COG0483	inositol monophosphate 1-phosphatase activity
JGY87_RS08925	COG4493	Belongs to the UPF0637 family
JGY87_RS08935	COG1914	H( )-stimulated, divalent metal cation uptake system
JGY87_RS08950	COG1177	transmembrane transport
JGY87_RS08955	COG1176	ABC-type spermidine putrescine transport system, permease component I
JGY87_RS08960	COG3842	ATPase activity
JGY87_RS08970	COG4476	Belongs to the UPF0223 family
JGY87_RS09000	COG0242	peptide deformylase activity
JGY87_RS09010	COG5503	Protein of unknown function (DUF1447)
JGY87_RS09015	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
JGY87_RS09020	COG0569	domain protein
JGY87_RS09025	COG1294	oxidase, subunit
JGY87_RS09030	COG1271	oxidase subunit
JGY87_RS09040	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
JGY87_RS09045	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
JGY87_RS09055	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
JGY87_RS09075	COG4172	Belongs to the ABC transporter superfamily
JGY87_RS09085	COG0151	Belongs to the GarS family
JGY87_RS09090	COG0138	bifunctional purine biosynthesis protein purh
JGY87_RS09100	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
JGY87_RS09110	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
JGY87_RS09115	COG0047	phosphoribosylformylglycinamidine synthase activity
JGY87_RS09120	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
JGY87_RS09125	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
JGY87_RS09130	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
JGY87_RS09135	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
JGY87_RS09140	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
JGY87_RS09145	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
JGY87_RS09145	COG1017	nitric oxide dioxygenase activity
JGY87_RS09155	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
JGY87_RS09160	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
JGY87_RS09165	COG1845	cytochrome c oxidase, subunit III
JGY87_RS09170	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
JGY87_RS09185	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
JGY87_RS09190	COG1316	TRANSCRIPTIONal
JGY87_RS09215	COG3594	Acyltransferase
JGY87_RS09220	COG0436	Aminotransferase
JGY87_RS09225	COG1846	Transcriptional regulator
JGY87_RS09230	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
JGY87_RS09235	COG2267	carboxylic ester hydrolase activity
JGY87_RS09240	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
JGY87_RS09245	COG1169	isochorismate synthase
JGY87_RS09250	COG1575	Belongs to the MenA family. Type 1 subfamily
JGY87_RS09260	COG2314	TM2 domain
JGY87_RS09280	COG4903	ComK protein
JGY87_RS09295	COG4873	Protein conserved in bacteria
JGY87_RS09305	COG0737	Belongs to the 5'-nucleotidase family
JGY87_RS09310	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
JGY87_RS09315	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JGY87_RS09320	COG0861	Integral membrane protein TerC family
JGY87_RS09325	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
JGY87_RS09335	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
JGY87_RS09340	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
JGY87_RS09345	COG2814	Major facilitator Superfamily
JGY87_RS09350	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
JGY87_RS09355	COG2382	esterase
JGY87_RS09360	COG1115	amino acid carrier protein
JGY87_RS09365	COG0628	permease
JGY87_RS09375	COG0475	glutathione-regulated potassium exporter activity
JGY87_RS09375	COG0569	domain protein
JGY87_RS09380	COG2239	Acts as a magnesium transporter
JGY87_RS09385	COG0564	pseudouridine synthase activity
JGY87_RS09390	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
JGY87_RS09395	COG2357	RelA SpoT domain protein
JGY87_RS09410	COG2346	COG2346, Truncated hemoglobins
JGY87_RS09415	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
JGY87_RS09420	COG1164	Oligoendopeptidase f
JGY87_RS09430	COG4862	establishment of competence for transformation
JGY87_RS09435	COG1393	Belongs to the ArsC family
JGY87_RS09440	COG0180	Tryptophanyl-tRNA synthetase
JGY87_RS09445	COG4166	transmembrane transport
JGY87_RS09450	COG4608	Belongs to the ABC transporter superfamily
JGY87_RS09455	COG0444	Belongs to the ABC transporter superfamily
JGY87_RS09460	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JGY87_RS09465	COG0601	transmembrane transport
JGY87_RS09485	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
JGY87_RS09495	COG0542	response to heat
JGY87_RS09510	COG0561	phosphatase activity
JGY87_RS09515	COG0446	pyridine nucleotide-disulphide oxidoreductase
JGY87_RS09525	COG0179	Fumarylacetoacetate (FAA) hydrolase
JGY87_RS09530	COG2311	Membrane
JGY87_RS09535	COG1074	ATP-dependent DNA helicase activity
JGY87_RS09540	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
JGY87_RS09555	COG0398	Pfam SNARE associated Golgi protein
JGY87_RS09560	COG0166	Belongs to the GPI family
JGY87_RS09565	COG0137	argininosuccinate synthase activity
JGY87_RS09570	COG0165	Argininosuccinate lyase
JGY87_RS09575	COG0584	glycerophosphoryl diester phosphodiesterase
JGY87_RS09585	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
JGY87_RS09590	COG1902	pentaerythritol trinitrate reductase activity
JGY87_RS09595	COG1098	S1 RNA binding domain
JGY87_RS09600	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
JGY87_RS09610	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
JGY87_RS09610	COG2111	Na H antiporter
JGY87_RS09615	COG2111	Na H antiporter
JGY87_RS09620	COG1006	Multisubunit Na H antiporter MnhC subunit
JGY87_RS09625	COG0651	ATP synthesis coupled electron transport
JGY87_RS09630	COG1863	multisubunit Na H antiporter MnhE subunit
JGY87_RS09635	COG2212	antiporter activity
JGY87_RS09640	COG1320	monovalent cation:proton antiporter activity
JGY87_RS09655	COG2050	protein possibly involved in aromatic compounds catabolism
JGY87_RS09660	COG2056	Na+-H+ antiporter family
JGY87_RS09665	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
JGY87_RS09670	COG1252	NADH dehydrogenase
JGY87_RS09675	COG0316	Belongs to the HesB IscA family
JGY87_RS09680	COG4844	belongs to the
JGY87_RS09685	COG1252	NADH dehydrogenase
JGY87_RS09690	COG4837	Protein of unknown function (DUF1462)
JGY87_RS09695	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
JGY87_RS09700	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
JGY87_RS09705	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
JGY87_RS09710	COG1696	Membrane protein involved in D-alanine export
JGY87_RS09715	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
JGY87_RS09725	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
JGY87_RS09730	COG0647	UMP catabolic process
JGY87_RS09735	COG2445	Protein of unknown function DUF86
JGY87_RS09745	COG4470	Protein conserved in bacteria
JGY87_RS09750	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
JGY87_RS09755	COG0737	Belongs to the 5'-nucleotidase family
JGY87_RS09760	COG0730	response to heat
JGY87_RS09765	COG1801	Protein of unknown function DUF72
JGY87_RS09770	COG2070	2-Nitropropane dioxygenase
JGY87_RS09775	COG1253	flavin adenine dinucleotide binding
JGY87_RS09785	COG0454	-acetyltransferase
JGY87_RS09790	COG3223	Belongs to the PsiE family
JGY87_RS09795	COG0719	Fe-S assembly protein
JGY87_RS09800	COG0822	iron-sulfur transferase activity
JGY87_RS09805	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
JGY87_RS09810	COG0719	Fe-S assembly protein
JGY87_RS09815	COG0396	ATPase activity
JGY87_RS09825	COG1253	flavin adenine dinucleotide binding
JGY87_RS09835	COG1464	Belongs to the NlpA lipoprotein family
JGY87_RS09840	COG2011	ABC-type metal ion transport system permease component
JGY87_RS09845	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
JGY87_RS09850	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JGY87_RS09855	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
JGY87_RS09860	COG0509	glycine decarboxylation via glycine cleavage system
JGY87_RS09865	COG1393	Belongs to the ArsC family
JGY87_RS09870	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JGY87_RS09875	COG0778	Nitroreductase
JGY87_RS09880	COG0710	3-dehydroquinate dehydratase activity
JGY87_RS09885	COG1764	response to oxidative stress
JGY87_RS09900	COG2851	Citrate transporter
JGY87_RS09915	COG2314	TM2 domain
JGY87_RS09955	COG2153	protein acetylation
JGY87_RS09960	COG0346	lactoylglutathione lyase activity
JGY87_RS09975	COG1073	alpha beta
JGY87_RS10005	COG0640	Transcriptional regulator
JGY87_RS10025	COG0346	lactoylglutathione lyase activity
JGY87_RS10070	COG0346	lactoylglutathione lyase activity
JGY87_RS10090	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
JGY87_RS10095	COG0557	exoribonuclease II activity
JGY87_RS10100	COG1647	Serine aminopeptidase, S33
JGY87_RS10105	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
JGY87_RS10115	COG0148	phosphopyruvate hydratase activity
JGY87_RS10120	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
JGY87_RS10125	COG0149	triose-phosphate isomerase activity
JGY87_RS10130	COG0126	phosphoglycerate kinase activity
JGY87_RS10155	COG1090	epimerase
JGY87_RS10165	COG0740	serine-type endopeptidase activity
JGY87_RS10175	COG1481	regulation of sporulation
JGY87_RS10180	COG0391	Required for morphogenesis under gluconeogenic growth conditions
JGY87_RS10185	COG1660	Displays ATPase and GTPase activities
JGY87_RS10190	COG0492	ferredoxin-NADP+ reductase activity
JGY87_RS10200	COG0110	maltose O-acetyltransferase activity
JGY87_RS10205	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
JGY87_RS10210	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
JGY87_RS10220	COG0556	nucleotide-excision repair
JGY87_RS10235	COG3942	CHAP domain
JGY87_RS10235	COG1388	LysM domain
JGY87_RS10245	COG0653	protein targeting
JGY87_RS10250	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
JGY87_RS10255	COG1040	competence protein
JGY87_RS10260	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
JGY87_RS10270	COG1739	Uncharacterized protein family UPF0029
JGY87_RS10275	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
JGY87_RS10280	COG2199	diguanylate cyclase activity
JGY87_RS10295	COG2195	Cleaves the N-terminal amino acid of tripeptides
JGY87_RS10300	COG1929	Belongs to the glycerate kinase type-1 family
JGY87_RS10320	COG0812	UDP-N-acetylmuramate dehydrogenase activity
JGY87_RS10335	COG4607	ABC-type enterochelin transport system periplasmic component
JGY87_RS10340	COG4604	ABC transporter, ATP-binding protein
JGY87_RS10345	COG4605	iron ion homeostasis
JGY87_RS10350	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JGY87_RS10355	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
JGY87_RS10360	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
JGY87_RS10365	COG1780	Probably involved in ribonucleotide reductase function
JGY87_RS10375	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
JGY87_RS10380	COG3104	oligopeptide transport
JGY87_RS10385	COG3104	oligopeptide transport
JGY87_RS10390	COG1597	lipid kinase activity
JGY87_RS10400	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
JGY87_RS10405	COG1174	glycine betaine transport
JGY87_RS10415	COG0514	ATP-dependent DNA helicase (RecQ)
JGY87_RS10420	COG0488	(ABC) transporter
JGY87_RS10430	COG1368	sulfuric ester hydrolase activity
JGY87_RS10440	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
JGY87_RS10455	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
JGY87_RS10460	COG0512	Glutamine amidotransferase of anthranilate synthase
JGY87_RS10460	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
JGY87_RS10465	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
JGY87_RS10470	COG0720	synthase
JGY87_RS10475	COG0602	queuosine metabolic process
JGY87_RS10490	COG0463	Glycosyl transferase, family 2
JGY87_RS10495	COG0656	L-ascorbic acid biosynthetic process
JGY87_RS10500	COG1253	flavin adenine dinucleotide binding
JGY87_RS10505	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
JGY87_RS10510	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JGY87_RS10510	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JGY87_RS10510	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JGY87_RS10515	COG1105	Belongs to the carbohydrate kinase PfkB family
JGY87_RS10520	COG1349	DNA-binding transcription factor activity
JGY87_RS10525	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
JGY87_RS10530	COG1210	Utp--glucose-1-phosphate uridylyltransferase
JGY87_RS10560	COG0039	L-malate dehydrogenase activity
JGY87_RS10565	COG0586	Pfam SNARE associated Golgi protein
JGY87_RS10575	COG4989	oxidoreductase activity
JGY87_RS10590	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
JGY87_RS10595	COG4988	ABC transporter
JGY87_RS10600	COG1968	undecaprenyl-diphosphatase activity
JGY87_RS10610	COG1671	Belongs to the UPF0178 family
JGY87_RS10615	COG1611	Belongs to the LOG family
JGY87_RS10620	COG1279	arginine transmembrane transporter activity
JGY87_RS10625	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JGY87_RS10655	COG2814	Major facilitator Superfamily
JGY87_RS10660	COG2839	Protein conserved in bacteria
JGY87_RS10665	COG2814	Major facilitator Superfamily
JGY87_RS10670	COG0583	DNA-binding transcription factor activity
JGY87_RS10680	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
JGY87_RS10690	COG0217	transcriptional regulatory protein
JGY87_RS10710	COG1388	LysM domain
JGY87_RS10710	COG3942	CHAP domain
JGY87_RS10715	COG0306	phosphate transporter
JGY87_RS10720	COG1392	Phosphate transport regulator
JGY87_RS10725	COG2205	protein histidine kinase activity
JGY87_RS10730	COG0745	RESPONSE REGULATOR receiver
JGY87_RS10735	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
JGY87_RS10745	COG0657	acetylesterase activity
JGY87_RS10750	COG3949	Membrane
JGY87_RS10760	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
JGY87_RS10765	COG1461	Dihydroxyacetone kinase
JGY87_RS10770	COG2376	Dihydroxyacetone kinase
JGY87_RS10775	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JGY87_RS10780	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JGY87_RS10785	COG1120	ATPase activity
JGY87_RS10790	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
JGY87_RS10795	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
JGY87_RS10800	COG1132	(ABC) transporter
JGY87_RS10810	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
JGY87_RS10820	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
JGY87_RS10825	COG1682	transport, permease protein
JGY87_RS10830	COG1134	teichoic acid transport
JGY87_RS10835	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
JGY87_RS10855	COG1108	ABC-type Mn2 Zn2 transport systems permease components
JGY87_RS10860	COG0803	Belongs to the bacterial solute-binding protein 9 family
JGY87_RS10870	COG1320	monovalent cation:proton antiporter activity
JGY87_RS10875	COG2212	antiporter activity
JGY87_RS10880	COG1863	multisubunit Na H antiporter MnhE subunit
JGY87_RS10885	COG0651	ATP synthesis coupled electron transport
JGY87_RS10890	COG1006	Multisubunit Na H antiporter MnhC subunit
JGY87_RS10895	COG2111	Na H antiporter
JGY87_RS10900	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
JGY87_RS10900	COG2111	Na H antiporter
JGY87_RS10940	COG0596	Alpha beta hydrolase
JGY87_RS10965	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JGY87_RS10970	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
JGY87_RS10980	COG0018	arginyl-trna synthetase
JGY87_RS10995	COG1078	dGTPase activity
JGY87_RS11000	COG0456	acetyltransferase
JGY87_RS11005	COG0655	NAD(P)H dehydrogenase (quinone) activity
JGY87_RS11010	COG0667	Aldo Keto reductase
JGY87_RS11015	COG4844	belongs to the
JGY87_RS11035	COG0095	Lipoate-protein ligase
JGY87_RS11040	COG0280	phosphate acetyltransferase
JGY87_RS11045	COG3253	May function as heme-dependent peroxidase
JGY87_RS11065	COG2363	Small membrane protein
JGY87_RS11075	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
JGY87_RS11080	COG0351	phosphomethylpyrimidine kinase
JGY87_RS11110	COG0183	Belongs to the thiolase family
JGY87_RS11115	COG0318	PFAM AMP-dependent synthetase and ligase
JGY87_RS11125	COG3493	citrate carrier protein
JGY87_RS11130	COG0384	phenazine biosynthesis protein PhzF
JGY87_RS11140	COG2329	Antibiotic biosynthesis monooxygenase
JGY87_RS11160	COG2832	Protein of unknown function (DUF454)
JGY87_RS11165	COG4565	transcriptional regulatory protein
JGY87_RS11170	COG3290	protein histidine kinase activity
JGY87_RS11175	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
JGY87_RS11180	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
JGY87_RS11185	COG0363	glucosamine-6-phosphate deaminase activity
JGY87_RS11195	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
JGY87_RS11200	COG1469	GTP cyclohydrolase I activity
JGY87_RS11215	COG0431	NADPH-dependent FMN reductase
JGY87_RS11220	COG0561	phosphatase activity
JGY87_RS11230	COG1428	Deoxynucleoside kinase
JGY87_RS11235	COG1428	Deoxynucleoside kinase
JGY87_RS11245	COG0546	phosphoglycolate phosphatase activity
JGY87_RS11265	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
JGY87_RS11280	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
JGY87_RS11285	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JGY87_RS11305	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
JGY87_RS11315	COG2824	Alkylphosphonate utilization operon protein PhnA
JGY87_RS11325	COG1113	amino acid transport
JGY87_RS11330	COG3239	Fatty acid desaturase
JGY87_RS11340	COG2040	homocysteine
JGY87_RS11345	COG0833	amino acid
JGY87_RS11355	COG0010	Belongs to the arginase family
JGY87_RS11360	COG1914	H( )-stimulated, divalent metal cation uptake system
JGY87_RS11375	COG1069	ribulokinase activity
JGY87_RS11380	COG1063	alcohol dehydrogenase
JGY87_RS11385	COG2814	Major facilitator Superfamily
JGY87_RS11390	COG1349	DNA-binding transcription factor activity
JGY87_RS11395	COG1132	(ABC) transporter
JGY87_RS11400	COG1028	Short-chain dehydrogenase reductase Sdr
JGY87_RS11405	COG1312	Catalyzes the dehydration of D-mannonate
JGY87_RS11410	COG1904	glucuronate isomerase
JGY87_RS11430	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JGY87_RS11445	COG0583	DNA-binding transcription factor activity
JGY87_RS11465	COG0667	Aldo Keto reductase
JGY87_RS11480	COG1686	Belongs to the peptidase S11 family
JGY87_RS11495	COG1028	Short-chain dehydrogenase reductase Sdr
JGY87_RS11500	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
JGY87_RS11505	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
JGY87_RS11545	COG1473	amidohydrolase
JGY87_RS11550	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
JGY87_RS11555	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
JGY87_RS11560	COG0049	tRNA binding
JGY87_RS11565	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
JGY87_RS11575	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
JGY87_RS11580	COG0085	RNA polymerase activity
JGY87_RS11585	COG2813	Specifically methylates the guanine in position
JGY87_RS11590	COG0222	ribosome binding
JGY87_RS11595	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
JGY87_RS11600	COG0081	regulation of translation
JGY87_RS11605	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
JGY87_RS11610	COG0250	Participates in transcription elongation, termination and antitermination
JGY87_RS11635	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
JGY87_RS11640	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
JGY87_RS11645	COG0215	cysteine-tRNA ligase activity
JGY87_RS11650	COG1045	serine acetyltransferase
JGY87_RS11655	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
JGY87_RS11660	COG4956	integral membrane protein (PIN domain superfamily)
JGY87_RS11665	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
JGY87_RS11670	COG0542	response to heat
JGY87_RS11675	COG3869	Catalyzes the specific phosphorylation of arginine residues in
JGY87_RS11680	COG3880	PFAM UvrB UvrC protein
JGY87_RS11685	COG4463	regulation of RNA biosynthetic process
JGY87_RS11690	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
JGY87_RS11695	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
JGY87_RS11700	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
JGY87_RS11705	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JGY87_RS11790	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
JGY87_RS11795	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
JGY87_RS11815	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
JGY87_RS11820	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
JGY87_RS11835	COG1098	S1 RNA binding domain
JGY87_RS11845	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
JGY87_RS11850	COG3956	TIGRFAM MazG family protein
JGY87_RS11855	COG2244	polysaccharide biosynthetic process
JGY87_RS11860	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
JGY87_RS11865	COG0193	aminoacyl-tRNA hydrolase activity
JGY87_RS11870	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
JGY87_RS11875	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
JGY87_RS11880	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
JGY87_RS11885	COG2088	sporulation resulting in formation of a cellular spore
JGY87_RS11890	COG0251	oxidation-reduction process
JGY87_RS11895	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
JGY87_RS11900	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
JGY87_RS11905	COG4466	Protein conserved in bacteria
JGY87_RS11910	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
JGY87_RS11915	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
JGY87_RS11920	COG0084	hydrolase, TatD family'
JGY87_RS11925	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JGY87_RS11925	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JGY87_RS11930	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
JGY87_RS11935	COG2827	Endonuclease containing a URI domain
JGY87_RS11940	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
JGY87_RS11945	COG4467	Involved in initiation control of chromosome replication
JGY87_RS11950	COG1774	PSP1 C-terminal conserved region
JGY87_RS11955	COG0470	DNA polymerase III
JGY87_RS11960	COG3870	Protein conserved in bacteria
JGY87_RS11965	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
JGY87_RS11970	COG1982	Orn Lys Arg decarboxylase major
JGY87_RS12005	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
JGY87_RS12010	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
JGY87_RS12015	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
JGY87_RS12020	COG3153	acetyltransferase
JGY87_RS12030	COG2188	Transcriptional regulator
JGY87_RS12035	COG0366	Alpha amylase catalytic
JGY87_RS12040	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JGY87_RS12040	COG1263	PTS System
JGY87_RS12050	COG0493	'glutamate synthase
JGY87_RS12055	COG0067	glutamate synthase
JGY87_RS12055	COG0069	glutamate synthase activity
JGY87_RS12055	COG0070	glutamate synthase
JGY87_RS12075	COG0004	ammonium transporteR
JGY87_RS12080	COG0494	nUDIX hydrolase
JGY87_RS12090	COG1388	LysM domain
JGY87_RS12090	COG3942	CHAP domain
JGY87_RS12100	COG0129	dihydroxy-acid dehydratase activity
JGY87_RS12115	COG0733	neurotransmitter:sodium symporter activity
JGY87_RS12120	COG1114	Component of the transport system for branched-chain amino acids
JGY87_RS12125	COG5646	InterPro IPR014922
JGY87_RS12130	COG2268	Band 7 protein
JGY87_RS12155	COG0789	Transcriptional regulator
JGY87_RS12170	COG4195	phage-related replication protein
JGY87_RS12175	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
JGY87_RS12180	COG2807	transmembrane transport
JGY87_RS12195	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
JGY87_RS12200	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
JGY87_RS12205	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
JGY87_RS12210	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
JGY87_RS12215	COG3257	ureidoglycine aminohydrolase activity
JGY87_RS12220	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
JGY87_RS12230	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
JGY87_RS12235	COG0406	alpha-ribazole phosphatase activity
JGY87_RS12245	COG1595	DNA-templated transcription, initiation
JGY87_RS12255	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
JGY87_RS12270	COG1876	peptidase activity
JGY87_RS12275	COG0753	catalase activity
JGY87_RS12285	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
JGY87_RS12290	COG1953	Uracil, thiamine, allantoin
JGY87_RS12295	COG2508	Transcriptional regulator
JGY87_RS12300	COG0456	acetyltransferase
JGY87_RS12300	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
JGY87_RS12305	COG2814	Major facilitator Superfamily
JGY87_RS12325	COG1301	dicarboxylic acid transport
JGY87_RS12340	COG0518	GMP synthase (glutamine-hydrolyzing) activity
JGY87_RS12340	COG0519	Catalyzes the synthesis of GMP from XMP
JGY87_RS12345	COG0516	GMP reductase activity
JGY87_RS12345	COG0517	IMP dehydrogenase activity
JGY87_RS12350	COG2233	PERMEase
JGY87_RS12355	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
JGY87_RS12370	COG5183	chlorophyll binding
JGY87_RS12375	COG1823	symporter activity
JGY87_RS12385	COG1760	l-serine dehydratase
JGY87_RS12390	COG1760	l-serine dehydratase
JGY87_RS12405	COG0778	Nitroreductase
JGY87_RS12410	COG0753	catalase activity
JGY87_RS12415	COG0450	alkyl hydroperoxide reductase
JGY87_RS12420	COG3634	alkyl hydroperoxide reductase activity
JGY87_RS12455	COG1280	lysine exporter protein (LysE YggA)
JGY87_RS12460	COG2076	Multidrug Resistance protein
JGY87_RS12465	COG2076	Multidrug Resistance protein
JGY87_RS12485	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
JGY87_RS12500	COG4195	phage-related replication protein
JGY87_RS12505	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
JGY87_RS12530	COG0583	DNA-binding transcription factor activity
JGY87_RS12540	COG3266	domain, Protein
JGY87_RS12540	COG4193	domain, Protein
JGY87_RS12540	COG5632	N-Acetylmuramoyl-L-alanine amidase
JGY87_RS12560	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JGY87_RS12565	COG2210	Belongs to the sulfur carrier protein TusA family
JGY87_RS12570	COG1937	Protein conserved in bacteria
JGY87_RS12575	COG0730	response to heat
JGY87_RS12585	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
JGY87_RS12625	COG0360	Binds together with S18 to 16S ribosomal RNA
JGY87_RS12635	COG0012	GTP binding
JGY87_RS12640	COG4481	Protein conserved in bacteria
JGY87_RS12645	COG0668	transmembrane transport
JGY87_RS12650	COG5609	conserved protein (DUF2294)
JGY87_RS12655	COG3002	Belongs to the UPF0753 family
JGY87_RS12660	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
JGY87_RS12665	COG1917	Cupin 2, conserved barrel domain protein
JGY87_RS12665	COG2207	Transcriptional regulator
JGY87_RS12670	COG1486	melibiose metabolic process
JGY87_RS12675	COG2211	Major facilitator Superfamily
JGY87_RS12680	COG2084	Dehydrogenase
JGY87_RS12685	COG1064	alcohol dehydrogenase
JGY87_RS12690	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
JGY87_RS12720	COG0577	efflux transmembrane transporter activity
JGY87_RS12725	COG1136	(ABC) transporter
JGY87_RS12730	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JGY87_RS12735	COG1288	antiporter activity
JGY87_RS12745	COG0789	Transcriptional regulator
JGY87_RS12745	COG4978	Transcriptional regulator
JGY87_RS12765	COG1012	belongs to the aldehyde dehydrogenase family
JGY87_RS12775	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
JGY87_RS12780	COG2814	Major facilitator Superfamily
JGY87_RS12785	COG1473	amidohydrolase
JGY87_RS12790	COG2814	Major facilitator Superfamily
JGY87_RS12795	COG1733	regulation of RNA biosynthetic process
JGY87_RS12800	COG2030	dehydratase
JGY87_RS12805	COG3759	membrane
JGY87_RS12810	COG2814	Major facilitator Superfamily
JGY87_RS12825	COG0772	Belongs to the SEDS family
JGY87_RS12830	COG2226	methyltransferase
JGY87_RS12835	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
JGY87_RS12845	COG0529	Catalyzes the synthesis of activated sulfate
JGY87_RS12850	COG2046	Belongs to the sulfate adenylyltransferase family
JGY87_RS12855	COG0730	response to heat
JGY87_RS12875	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
JGY87_RS12880	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
JGY87_RS12885	COG0175	sulfate reduction
JGY87_RS12890	COG1475	DNA binding
JGY87_RS12895	COG0626	cystathionine gamma-synthase activity
JGY87_RS12900	COG0626	cystathionine gamma-synthase activity
JGY87_RS12905	COG0646	methionine synthase
JGY87_RS12905	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
JGY87_RS12910	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
JGY87_RS12920	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
JGY87_RS12945	COG0183	Belongs to the thiolase family
JGY87_RS12955	COG1960	acyl-CoA dehydrogenase activity
JGY87_RS12960	COG0318	PFAM AMP-dependent synthetase and ligase
JGY87_RS12970	COG2239	Acts as a magnesium transporter
JGY87_RS12975	COG0803	Belongs to the bacterial solute-binding protein 9 family
JGY87_RS12980	COG1108	ABC-type Mn2 Zn2 transport systems permease components
JGY87_RS13000	COG0561	phosphatase activity
JGY87_RS13005	COG0583	DNA-binding transcription factor activity
JGY87_RS13010	COG1607	acyl-coa hydrolase
JGY87_RS13020	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
JGY87_RS13020	COG2755	lipolytic protein G-D-S-L family
JGY87_RS13030	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
JGY87_RS13030	COG0463	Glycosyl transferase, family 2
JGY87_RS13035	COG0463	Glycosyl transferase, family 2
JGY87_RS13035	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
JGY87_RS13060	COG1028	Short-chain dehydrogenase reductase Sdr
JGY87_RS13065	COG0531	amino acid
JGY87_RS13070	COG0656	L-ascorbic acid biosynthetic process
JGY87_RS13075	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
JGY87_RS13100	COG0789	Transcriptional regulator
JGY87_RS13110	COG0450	alkyl hydroperoxide reductase
JGY87_RS13115	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
JGY87_RS13125	COG2271	Major facilitator Superfamily
JGY87_RS13130	COG1966	Carbon starvation protein
JGY87_RS13140	COG0357	Ribosomal RNA small subunit methyltransferase G
JGY87_RS13145	COG0445	tRNA wobble uridine modification
JGY87_RS13150	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
JGY87_RS13155	COG0594	ribonuclease P activity