locus-tag	class	description
FNS06_RS00010	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FNS06_RS00020	COG1492	cobalamin metabolic process
FNS06_RS00025	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
FNS06_RS00035	COG4948	Mandelate Racemase Muconate Lactonizing
FNS06_RS00070	COG0768	penicillin binding
FNS06_RS00075	COG0772	Belongs to the SEDS family
FNS06_RS00085	COG3237	CsbD-like
FNS06_RS00110	COG1028	Short-chain dehydrogenase reductase Sdr
FNS06_RS00115	COG0431	NADPH-dependent FMN reductase
FNS06_RS00120	COG0765	amino acid transport
FNS06_RS00125	COG0765	amino acid transport
FNS06_RS00145	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
FNS06_RS00180	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FNS06_RS00195	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FNS06_RS00200	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FNS06_RS00205	COG0330	HflC and HflK could
FNS06_RS00210	COG1585	Membrane protein implicated in regulation of membrane protease activity
FNS06_RS00270	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
FNS06_RS00275	COG1477	protein flavinylation
FNS06_RS00295	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
FNS06_RS00335	COG0683	leucine binding
FNS06_RS00350	COG0559	Belongs to the binding-protein-dependent transport system permease family
FNS06_RS00360	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FNS06_RS00365	COG2188	Transcriptional regulator
FNS06_RS00375	COG1802	Transcriptional regulator
FNS06_RS00380	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FNS06_RS00385	COG4597	amino acid ABC transporter
FNS06_RS00390	COG0765	amino acid transport
FNS06_RS00395	COG0747	negative chemotaxis
FNS06_RS00400	COG0601	transmembrane transport
FNS06_RS00405	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FNS06_RS00410	COG0444	Belongs to the ABC transporter superfamily
FNS06_RS00415	COG4608	Belongs to the ABC transporter superfamily
FNS06_RS00430	COG0829	nickel cation binding
FNS06_RS00435	COG0831	urea catabolic process
FNS06_RS00435	COG0832	Belongs to the urease beta subunit family
FNS06_RS00440	COG0804	urea catabolic process
FNS06_RS00445	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
FNS06_RS00450	COG0830	nickel cation binding
FNS06_RS00455	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
FNS06_RS00470	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FNS06_RS00470	COG0574	Belongs to the PEP-utilizing enzyme family
FNS06_RS00500	COG1053	succinate dehydrogenase
FNS06_RS00505	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
FNS06_RS00515	COG2301	Belongs to the HpcH HpaI aldolase family
FNS06_RS00535	COG0318	PFAM AMP-dependent synthetase and ligase
FNS06_RS00550	COG1028	Short-chain dehydrogenase reductase Sdr
FNS06_RS00560	COG0604	alcohol dehydrogenase
FNS06_RS00560	COG3321	synthase
FNS06_RS00560	COG1028	Short-chain dehydrogenase reductase Sdr
FNS06_RS00605	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FNS06_RS00610	COG2207	Transcriptional regulator
FNS06_RS00615	COG4221	oxidoreductase activity
FNS06_RS00635	COG0824	Thioesterase
FNS06_RS00640	COG0071	Belongs to the small heat shock protein (HSP20) family
FNS06_RS00645	COG0254	rRNA binding
FNS06_RS00650	COG1965	Belongs to the frataxin family
FNS06_RS00670	COG0483	inositol monophosphate 1-phosphatase activity
FNS06_RS00675	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FNS06_RS00680	COG0352	thiamine-phosphate diphosphorylase activity
FNS06_RS00685	COG1830	Aldolase
FNS06_RS00720	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FNS06_RS00725	COG1692	metallophosphoesterase
FNS06_RS00735	COG0217	transcriptional regulatory protein
FNS06_RS00745	COG0632	four-way junction helicase activity
FNS06_RS00750	COG2255	four-way junction helicase activity
FNS06_RS00755	COG0824	Thioesterase
FNS06_RS00780	COG2885	chlorophyll binding
FNS06_RS00790	COG0037	tRNA processing
FNS06_RS00800	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FNS06_RS00815	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FNS06_RS00820	COG0351	phosphomethylpyrimidine kinase
FNS06_RS00830	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FNS06_RS00855	COG4452	Inner membrane protein CreD
FNS06_RS00870	COG0473	3-isopropylmalate dehydrogenase activity
FNS06_RS00875	COG2084	Dehydrogenase
FNS06_RS00880	COG0028	Belongs to the TPP enzyme family
FNS06_RS00885	COG1960	acyl-CoA dehydrogenase activity
FNS06_RS00895	COG3191	aminopeptidase activity
FNS06_RS00905	COG3177	Filamentation induced by cAMP protein fic
FNS06_RS00910	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FNS06_RS00915	COG0228	four-way junction DNA binding
FNS06_RS00920	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FNS06_RS00930	COG0335	large ribosomal subunit rRNA binding
FNS06_RS00935	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FNS06_RS00940	COG0066	3-isopropylmalate dehydratase activity
FNS06_RS00955	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
FNS06_RS00965	COG0776	regulation of translation
FNS06_RS00970	COG0287	Prephenate dehydrogenase
FNS06_RS00975	COG0287	Prephenate dehydrogenase
FNS06_RS00980	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FNS06_RS00995	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FNS06_RS01015	COG1028	Short-chain dehydrogenase reductase Sdr
FNS06_RS01020	COG0183	Belongs to the thiolase family
FNS06_RS01025	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FNS06_RS01030	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
FNS06_RS01040	COG0318	PFAM AMP-dependent synthetase and ligase
FNS06_RS01045	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FNS06_RS01050	COG1396	sequence-specific DNA binding
FNS06_RS01060	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FNS06_RS01075	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
FNS06_RS01085	COG2884	Cell division ATP-binding protein ftsE
FNS06_RS01090	COG0457	Tetratricopeptide repeat
FNS06_RS01110	COG0165	Argininosuccinate lyase
FNS06_RS01115	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FNS06_RS01125	COG1250	3-hydroxyacyl-CoA dehydrogenase
FNS06_RS01135	COG2086	electron transfer activity
FNS06_RS01160	COG0784	Response regulator, receiver
FNS06_RS01160	COG4191	Histidine kinase
FNS06_RS01165	COG0784	Response regulator, receiver
FNS06_RS01170	COG1028	Short-chain dehydrogenase reductase Sdr
FNS06_RS01180	COG3842	ATPase activity
FNS06_RS01220	COG1028	Short-chain dehydrogenase reductase Sdr
FNS06_RS01265	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
FNS06_RS01270	COG1028	Short-chain dehydrogenase reductase Sdr
FNS06_RS01275	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FNS06_RS01290	COG2223	nitrite transmembrane transporter activity
FNS06_RS01295	COG4133	protoheme IX ABC transporter activity
FNS06_RS01305	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FNS06_RS01315	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
FNS06_RS01320	COG1138	Cytochrome C-type biogenesis protein
FNS06_RS01325	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FNS06_RS01330	COG3088	subunit of a heme lyase
FNS06_RS01335	COG4235	cytochrome complex assembly
FNS06_RS01340	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
FNS06_RS01400	COG0405	Gamma-glutamyltransferase
FNS06_RS01405	COG0842	Transport permease protein
FNS06_RS01410	COG0668	transmembrane transport
FNS06_RS01415	COG1280	lysine exporter protein (LysE YggA)
FNS06_RS01430	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FNS06_RS01435	COG0386	Belongs to the glutathione peroxidase family
FNS06_RS01460	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FNS06_RS01465	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FNS06_RS01480	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FNS06_RS01485	COG0302	gtp cyclohydrolase
FNS06_RS01495	COG2885	chlorophyll binding
FNS06_RS01495	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
FNS06_RS01510	COG2223	nitrite transmembrane transporter activity
FNS06_RS01520	COG1217	gtp-binding protein TYPA
FNS06_RS01525	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FNS06_RS01535	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FNS06_RS01540	COG4597	amino acid ABC transporter
FNS06_RS01545	COG0765	amino acid transport
FNS06_RS01550	COG1126	abc transporter atp-binding protein
FNS06_RS01555	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FNS06_RS01570	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FNS06_RS01580	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
FNS06_RS01585	COG0456	acetyltransferase
FNS06_RS01590	COG0484	heat shock protein binding
FNS06_RS01595	COG0443	Heat shock 70 kDa protein
FNS06_RS01600	COG0220	tRNA (guanine-N7-)-methyltransferase activity
FNS06_RS01605	COG0779	Required for maturation of 30S ribosomal subunits
FNS06_RS01620	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
FNS06_RS01630	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FNS06_RS01645	COG0584	glycerophosphoryl diester phosphodiesterase
FNS06_RS01660	COG1592	Rubrerythrin
FNS06_RS01690	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
FNS06_RS01695	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
FNS06_RS01700	COG1454	alcohol dehydrogenase
FNS06_RS01705	COG0583	DNA-binding transcription factor activity
FNS06_RS01720	COG0151	Belongs to the GarS family
FNS06_RS01725	COG1570	exodeoxyribonuclease VII activity
FNS06_RS01760	COG0583	DNA-binding transcription factor activity
FNS06_RS01765	COG2233	PERMEase
FNS06_RS01770	COG0436	Aminotransferase
FNS06_RS01790	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FNS06_RS01845	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FNS06_RS01870	COG2188	Transcriptional regulator
FNS06_RS01890	COG1715	Restriction endonuclease
FNS06_RS01915	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FNS06_RS01915	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FNS06_RS01925	COG1131	(ABC) transporter
FNS06_RS01930	COG2267	carboxylic ester hydrolase activity
FNS06_RS01935	COG0745	RESPONSE REGULATOR receiver
FNS06_RS01940	COG2205	protein histidine kinase activity
FNS06_RS01965	COG2205	protein histidine kinase activity
FNS06_RS01965	COG0784	Response regulator, receiver
FNS06_RS01970	COG0028	Belongs to the TPP enzyme family
FNS06_RS01980	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FNS06_RS01985	COG0022	dehydrogenase e1 component
FNS06_RS01990	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FNS06_RS01995	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FNS06_RS02005	COG3246	L-lysine catabolic process to acetate
FNS06_RS02025	COG0583	DNA-binding transcription factor activity
FNS06_RS02040	COG3383	formate dehydrogenase (NAD+) activity
FNS06_RS02045	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
FNS06_RS02055	COG0784	Response regulator, receiver
FNS06_RS02055	COG2205	protein histidine kinase activity
FNS06_RS02055	COG5002	protein histidine kinase activity
FNS06_RS02065	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FNS06_RS02125	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FNS06_RS02135	COG3181	Tripartite tricarboxylate transporter family receptor
FNS06_RS02160	COG3177	Filamentation induced by cAMP protein fic
FNS06_RS02220	COG0726	polysaccharide deacetylase
FNS06_RS02265	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FNS06_RS02270	COG2181	nitrate reductase activity
FNS06_RS02275	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
FNS06_RS02280	COG1140	nitrate reductase beta subunit
FNS06_RS02285	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
FNS06_RS02290	COG2223	nitrite transmembrane transporter activity
FNS06_RS02310	COG0644	oxidoreductase
FNS06_RS02325	COG0577	efflux transmembrane transporter activity
FNS06_RS02335	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FNS06_RS02340	COG1136	(ABC) transporter
FNS06_RS02365	COG3546	catalase activity
FNS06_RS02380	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FNS06_RS02390	COG0785	Cytochrome C biogenesis protein
FNS06_RS02400	COG1028	Short-chain dehydrogenase reductase Sdr
FNS06_RS02435	COG0028	Belongs to the TPP enzyme family
FNS06_RS02465	COG1228	amidohydrolase
FNS06_RS02480	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FNS06_RS02510	COG0488	(ABC) transporter
FNS06_RS02565	COG2983	Belongs to the UPF0260 family
FNS06_RS02575	COG0277	FAD linked oxidase domain protein
FNS06_RS02605	COG1741	Belongs to the pirin family
FNS06_RS02615	COG2378	regulation of single-species biofilm formation
FNS06_RS02645	COG0714	Associated with various cellular activities
FNS06_RS02665	COG0617	tRNA 3'-terminal CCA addition
FNS06_RS02680	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FNS06_RS02690	COG0148	phosphopyruvate hydratase activity
FNS06_RS02700	COG2814	Major facilitator Superfamily
FNS06_RS02705	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
FNS06_RS02720	COG1067	ATP-dependent peptidase activity
FNS06_RS02740	COG0596	Alpha beta hydrolase
FNS06_RS02745	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FNS06_RS02770	COG1024	Enoyl-CoA hydratase
FNS06_RS02785	COG1028	Short-chain dehydrogenase reductase Sdr
FNS06_RS02790	COG1612	heme a metabolic process
FNS06_RS02795	COG5425	PFAM Usg family protein
FNS06_RS02800	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
FNS06_RS02805	COG0459	protein refolding
FNS06_RS02820	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FNS06_RS02825	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FNS06_RS02855	COG0259	pyridoxamine-phosphate oxidase activity
FNS06_RS02865	COG0484	heat shock protein binding
FNS06_RS02870	COG1295	ribonuclease BN
FNS06_RS02875	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FNS06_RS02880	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
FNS06_RS02890	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FNS06_RS02895	COG0297	glycogen (starch) synthase activity
FNS06_RS02905	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
FNS06_RS02910	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
FNS06_RS02915	COG0142	geranyltranstransferase activity
FNS06_RS02940	COG0123	including yeast histone deacetylase and acetoin utilization protein
FNS06_RS02970	COG0666	response to abiotic stimulus
FNS06_RS02975	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FNS06_RS02980	COG0747	negative chemotaxis
FNS06_RS02985	COG0747	negative chemotaxis
FNS06_RS02995	COG0747	negative chemotaxis
FNS06_RS03000	COG4166	transmembrane transport
FNS06_RS03010	COG0601	transmembrane transport
FNS06_RS03015	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FNS06_RS03020	COG0444	Belongs to the ABC transporter superfamily
FNS06_RS03025	COG4608	Belongs to the ABC transporter superfamily
FNS06_RS03030	COG5002	protein histidine kinase activity
FNS06_RS03035	COG0745	RESPONSE REGULATOR receiver
FNS06_RS03050	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FNS06_RS03060	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FNS06_RS03075	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
FNS06_RS03090	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
FNS06_RS03100	COG1573	uracil-dna glycosylase
FNS06_RS03115	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FNS06_RS03120	COG0583	DNA-binding transcription factor activity
FNS06_RS03140	COG1802	Transcriptional regulator
FNS06_RS03145	COG0747	negative chemotaxis
FNS06_RS03150	COG0601	transmembrane transport
FNS06_RS03155	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FNS06_RS03160	COG0444	Belongs to the ABC transporter superfamily
FNS06_RS03185	COG1051	belongs to the nudix hydrolase family
FNS06_RS03190	COG0793	Belongs to the peptidase S41A family
FNS06_RS03200	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
FNS06_RS03205	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
FNS06_RS03210	COG3842	ATPase activity
FNS06_RS03220	COG1176	ABC-type spermidine putrescine transport system, permease component I
FNS06_RS03245	COG4948	Mandelate Racemase Muconate Lactonizing
FNS06_RS03250	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
FNS06_RS03255	COG0799	negative regulation of ribosome biogenesis
FNS06_RS03275	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FNS06_RS03280	COG0211	Belongs to the bacterial ribosomal protein bL27 family
FNS06_RS03285	COG0261	This protein binds to 23S rRNA in the presence of protein L20
FNS06_RS03305	COG0446	pyridine nucleotide-disulphide oxidoreductase
FNS06_RS03305	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FNS06_RS03315	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FNS06_RS03335	COG0747	negative chemotaxis
FNS06_RS03345	COG2308	Evidence 4 Homologs of previously reported genes of
FNS06_RS03345	COG2307	Protein conserved in bacteria
FNS06_RS03355	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
FNS06_RS03380	COG2072	flavoprotein involved in K transport
FNS06_RS03390	COG0028	Belongs to the TPP enzyme family
FNS06_RS03410	COG1309	transcriptional regulator
FNS06_RS03455	COG1741	Belongs to the pirin family
FNS06_RS03505	COG0589	response to stress
FNS06_RS03510	COG0659	secondary active sulfate transmembrane transporter activity
FNS06_RS03520	COG2326	polyphosphate kinase activity
FNS06_RS03545	COG1744	ABC transporter substrate-binding protein PnrA-like
FNS06_RS03580	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
FNS06_RS03585	COG1262	PFAM Formylglycine-generating sulfatase enzyme
FNS06_RS03590	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FNS06_RS03595	COG1116	anion transmembrane transporter activity
FNS06_RS03615	COG1309	transcriptional regulator
FNS06_RS03630	COG1132	(ABC) transporter
FNS06_RS03660	COG0513	Belongs to the DEAD box helicase family
FNS06_RS03665	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FNS06_RS03675	COG0154	amidase activity
FNS06_RS03680	COG1802	Transcriptional regulator
FNS06_RS03685	COG0747	negative chemotaxis
FNS06_RS03695	COG0747	negative chemotaxis
FNS06_RS03710	COG2721	sulfolactate sulfo-lyase activity
FNS06_RS03715	COG2721	sulfolactate sulfo-lyase activity
FNS06_RS03725	COG1970	mechanosensitive ion channel activity
FNS06_RS03740	COG1560	Kdo2-lipid A biosynthetic process
FNS06_RS03745	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FNS06_RS03750	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FNS06_RS03755	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FNS06_RS03760	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FNS06_RS03765	COG1028	Short-chain dehydrogenase reductase Sdr
FNS06_RS03785	COG1028	Short-chain dehydrogenase reductase Sdr
FNS06_RS03805	COG2066	Belongs to the glutaminase family
FNS06_RS03805	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
FNS06_RS03820	COG1366	Belongs to the anti-sigma-factor antagonist family
FNS06_RS03825	COG5002	protein histidine kinase activity
FNS06_RS03825	COG0784	Response regulator, receiver
FNS06_RS03830	COG0745	RESPONSE REGULATOR receiver
FNS06_RS03835	COG3437	response regulator, receiver
FNS06_RS03855	COG0656	L-ascorbic acid biosynthetic process
FNS06_RS03860	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
FNS06_RS03900	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
FNS06_RS03910	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
FNS06_RS03915	COG2857	Cytochrome c1
FNS06_RS03915	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
FNS06_RS03925	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
FNS06_RS03930	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
FNS06_RS03940	COG0412	Dienelactone hydrolase
FNS06_RS03945	COG1473	amidohydrolase
FNS06_RS03950	COG1473	amidohydrolase
FNS06_RS03955	COG1473	amidohydrolase
FNS06_RS03975	COG0756	dUTP diphosphatase activity
FNS06_RS03980	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FNS06_RS03980	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
FNS06_RS03985	COG1024	Enoyl-CoA hydratase
FNS06_RS03985	COG1250	3-hydroxyacyl-CoA dehydrogenase
FNS06_RS04005	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FNS06_RS04015	COG0670	Belongs to the BI1 family
FNS06_RS04025	COG1136	(ABC) transporter
FNS06_RS04035	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FNS06_RS04035	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FNS06_RS04050	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FNS06_RS04065	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
FNS06_RS04080	COG0028	Belongs to the TPP enzyme family
FNS06_RS04085	COG1253	flavin adenine dinucleotide binding
FNS06_RS04125	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FNS06_RS04160	COG5487	UPF0391 membrane protein
FNS06_RS04180	COG1250	3-hydroxyacyl-CoA dehydrogenase
FNS06_RS04180	COG1024	Enoyl-CoA hydratase
FNS06_RS04185	COG0753	catalase activity
FNS06_RS04195	COG2814	Major facilitator Superfamily
FNS06_RS04210	COG2814	Major facilitator Superfamily
FNS06_RS04220	COG2204	response regulator
FNS06_RS04235	COG2358	TRAP transporter, solute receptor (TAXI family
FNS06_RS04240	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FNS06_RS04240	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FNS06_RS04265	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
FNS06_RS04275	COG2986	histidine ammonia-lyase
FNS06_RS04280	COG1228	amidohydrolase
FNS06_RS04315	COG0411	ABC transporter
FNS06_RS04330	COG1960	acyl-CoA dehydrogenase activity
FNS06_RS04335	COG0277	FAD linked oxidase domain protein
FNS06_RS04340	COG0009	L-threonylcarbamoyladenylate synthase
FNS06_RS04355	COG3540	Alkaline phosphatase
FNS06_RS04370	COG1175	transmembrane transport
FNS06_RS04395	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FNS06_RS04400	COG0235	Class ii aldolase
FNS06_RS04410	COG1070	Carbohydrate kinase
FNS06_RS04415	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FNS06_RS04430	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
FNS06_RS04450	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FNS06_RS04455	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FNS06_RS04490	COG0559	Belongs to the binding-protein-dependent transport system permease family
FNS06_RS04520	COG2233	PERMEase
FNS06_RS04525	COG0583	DNA-binding transcription factor activity
FNS06_RS04580	COG4771	TonB-dependent receptor
FNS06_RS04585	COG2814	Major facilitator Superfamily
FNS06_RS04595	COG4608	Belongs to the ABC transporter superfamily
FNS06_RS04600	COG0444	Belongs to the ABC transporter superfamily
FNS06_RS04605	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FNS06_RS04610	COG0601	transmembrane transport
FNS06_RS04615	COG0747	negative chemotaxis
FNS06_RS04620	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FNS06_RS04625	COG0583	DNA-binding transcription factor activity
FNS06_RS04635	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
FNS06_RS04650	COG2188	Transcriptional regulator
FNS06_RS04660	COG3842	ATPase activity
FNS06_RS04665	COG1175	transmembrane transport
FNS06_RS04670	COG0395	ABC-type sugar transport system, permease component
FNS06_RS04675	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
FNS06_RS04680	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FNS06_RS04700	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
FNS06_RS04725	COG1396	sequence-specific DNA binding
FNS06_RS04770	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FNS06_RS04785	COG1609	Transcriptional regulator
FNS06_RS04800	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FNS06_RS04810	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FNS06_RS04810	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FNS06_RS04830	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FNS06_RS04835	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FNS06_RS04860	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FNS06_RS04865	COG0527	aspartate kinase activity
FNS06_RS04870	COG2070	2-Nitropropane dioxygenase
FNS06_RS04885	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
FNS06_RS04890	COG0124	histidyl-tRNA synthetase
FNS06_RS04895	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
FNS06_RS04905	COG2890	protein-(glutamine-N5) methyltransferase activity
FNS06_RS04915	COG0542	response to heat
FNS06_RS04920	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
FNS06_RS04930	COG2358	TRAP transporter, solute receptor (TAXI family
FNS06_RS04945	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
FNS06_RS04955	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FNS06_RS04960	COG0235	Class ii aldolase
FNS06_RS04965	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FNS06_RS05025	COG0444	Belongs to the ABC transporter superfamily
FNS06_RS05030	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FNS06_RS05040	COG4166	transmembrane transport
FNS06_RS05045	COG4608	Belongs to the ABC transporter superfamily
FNS06_RS05060	COG4172	Belongs to the ABC transporter superfamily
FNS06_RS05065	COG0444	Belongs to the ABC transporter superfamily
FNS06_RS05070	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FNS06_RS05075	COG0601	transmembrane transport
FNS06_RS05080	COG0747	negative chemotaxis
FNS06_RS05090	COG1250	3-hydroxyacyl-CoA dehydrogenase
FNS06_RS05105	COG3246	L-lysine catabolic process to acetate
FNS06_RS05120	COG0406	alpha-ribazole phosphatase activity
FNS06_RS05125	COG1414	Transcriptional regulator
FNS06_RS05130	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FNS06_RS05150	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FNS06_RS05155	COG0803	Belongs to the bacterial solute-binding protein 9 family
FNS06_RS05160	COG1121	(ABC) transporter
FNS06_RS05165	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FNS06_RS05170	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FNS06_RS05190	COG3842	ATPase activity
FNS06_RS05200	COG1178	ABC-type Fe3 transport system permease component
FNS06_RS05215	COG4608	Belongs to the ABC transporter superfamily
FNS06_RS05220	COG0444	Belongs to the ABC transporter superfamily
FNS06_RS05225	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FNS06_RS05240	COG0747	negative chemotaxis
FNS06_RS05250	COG1686	Belongs to the peptidase S11 family
FNS06_RS05265	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
FNS06_RS05285	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FNS06_RS05290	COG2723	6-phospho-beta-galactosidase activity
FNS06_RS05295	COG4178	(ABC) transporter
FNS06_RS05310	COG0516	GMP reductase activity
FNS06_RS05310	COG0517	IMP dehydrogenase activity
FNS06_RS05325	COG0583	DNA-binding transcription factor activity
FNS06_RS05345	COG0318	PFAM AMP-dependent synthetase and ligase
FNS06_RS05365	COG0277	FAD linked oxidase domain protein
FNS06_RS05370	COG0277	FAD linked oxidase domain protein
FNS06_RS05375	COG0247	lactate metabolic process
FNS06_RS05390	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FNS06_RS05390	COG3952	Lipid A Biosynthesis
FNS06_RS05395	COG0463	Glycosyl transferase, family 2
FNS06_RS05400	COG5508	conserved small protein
FNS06_RS05410	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FNS06_RS05410	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FNS06_RS05415	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FNS06_RS05425	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FNS06_RS05440	COG0583	DNA-binding transcription factor activity
FNS06_RS05445	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FNS06_RS05455	COG0747	negative chemotaxis
FNS06_RS05460	COG0601	transmembrane transport
FNS06_RS05465	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FNS06_RS05470	COG4172	Belongs to the ABC transporter superfamily
FNS06_RS05475	COG3609	addiction module antidote protein, CC2985 family
FNS06_RS05485	COG0138	bifunctional purine biosynthesis protein purh
FNS06_RS05490	COG0783	Belongs to the Dps family
FNS06_RS05505	COG1024	Enoyl-CoA hydratase
FNS06_RS05505	COG1250	3-hydroxyacyl-CoA dehydrogenase
FNS06_RS05510	COG0242	peptide deformylase activity
FNS06_RS05530	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
FNS06_RS05560	COG1215	transferase activity, transferring glycosyl groups
FNS06_RS05580	COG2076	Multidrug Resistance protein
FNS06_RS05585	COG0784	Response regulator, receiver
FNS06_RS05585	COG4191	Histidine kinase
FNS06_RS05590	COG2244	polysaccharide biosynthetic process
FNS06_RS05595	COG0318	PFAM AMP-dependent synthetase and ligase
FNS06_RS05605	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FNS06_RS05610	COG0156	8-amino-7-oxononanoate synthase activity
FNS06_RS05655	COG0456	acetyltransferase
FNS06_RS05680	COG1396	sequence-specific DNA binding
FNS06_RS05685	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
FNS06_RS05695	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
FNS06_RS05730	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FNS06_RS05735	COG2030	dehydratase
FNS06_RS05740	COG1024	Enoyl-CoA hydratase
FNS06_RS05745	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FNS06_RS05755	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FNS06_RS05765	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FNS06_RS05765	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FNS06_RS05775	COG1960	acyl-CoA dehydrogenase activity
FNS06_RS05780	COG4670	ketone body catabolic process
FNS06_RS05790	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FNS06_RS05835	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FNS06_RS05840	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FNS06_RS05845	COG2188	Transcriptional regulator
FNS06_RS05850	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
FNS06_RS05860	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FNS06_RS05865	COG4597	amino acid ABC transporter
FNS06_RS05870	COG0765	amino acid transport
FNS06_RS05875	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FNS06_RS05885	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FNS06_RS05890	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
FNS06_RS05895	COG4608	Belongs to the ABC transporter superfamily
FNS06_RS05905	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FNS06_RS05910	COG0601	transmembrane transport
FNS06_RS05915	COG0747	negative chemotaxis
FNS06_RS05930	COG2823	Periplasmic or secreted lipoprotein
FNS06_RS05950	COG4608	Belongs to the ABC transporter superfamily
FNS06_RS05955	COG0444	Belongs to the ABC transporter superfamily
FNS06_RS05960	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FNS06_RS05965	COG0601	transmembrane transport
FNS06_RS05970	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FNS06_RS05990	COG1028	Short-chain dehydrogenase reductase Sdr
FNS06_RS05995	COG0747	negative chemotaxis
FNS06_RS06005	COG0471	metal ion transport
FNS06_RS06010	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FNS06_RS06020	COG3795	YCII-related domain
FNS06_RS06025	COG4941	Belongs to the sigma-70 factor family
FNS06_RS06040	COG0625	glutathione transferase activity
FNS06_RS06050	COG1250	3-hydroxyacyl-CoA dehydrogenase
FNS06_RS06065	COG1022	Amp-dependent synthetase and ligase
FNS06_RS06070	COG1309	transcriptional regulator
FNS06_RS06090	COG1176	ABC-type spermidine putrescine transport system, permease component I
FNS06_RS06095	COG1177	transmembrane transport
FNS06_RS06100	COG4689	acetoacetate decarboxylase
FNS06_RS06135	COG0601	transmembrane transport
FNS06_RS06140	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FNS06_RS06145	COG0444	Belongs to the ABC transporter superfamily
FNS06_RS06195	COG0066	3-isopropylmalate dehydratase activity
FNS06_RS06210	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FNS06_RS06220	COG1629	transport
FNS06_RS06220	COG4206	TonB-dependent receptor
FNS06_RS06255	COG3750	Belongs to the UPF0335 family
FNS06_RS06290	COG0469	pyruvate kinase activity
FNS06_RS06300	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FNS06_RS06300	COG2169	Transcriptional regulator
FNS06_RS06315	COG4106	trans-aconitate 2-methyltransferase activity
FNS06_RS06330	COG3639	organic phosphonate transmembrane transporter activity
FNS06_RS06335	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
FNS06_RS06365	COG0546	phosphoglycolate phosphatase activity
FNS06_RS06370	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FNS06_RS06375	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FNS06_RS06390	COG3193	protein, possibly involved in utilization of glycolate and propanediol
FNS06_RS06410	COG0583	DNA-binding transcription factor activity
FNS06_RS06445	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
FNS06_RS06460	COG1858	cytochrome C peroxidase
FNS06_RS06465	COG0586	Pfam SNARE associated Golgi protein
FNS06_RS06470	COG2130	NADP-dependent
FNS06_RS06490	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FNS06_RS06500	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FNS06_RS06515	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
FNS06_RS06520	COG4566	intracellular signal transduction
FNS06_RS06525	COG4191	Histidine kinase
FNS06_RS06585	COG0484	heat shock protein binding
FNS06_RS06610	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
FNS06_RS06615	COG0247	lactate metabolic process
FNS06_RS06615	COG0277	FAD linked oxidase domain protein
FNS06_RS06620	COG1802	Transcriptional regulator
FNS06_RS06630	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FNS06_RS06645	COG1671	Belongs to the UPF0178 family
FNS06_RS06650	COG2130	NADP-dependent
FNS06_RS06665	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FNS06_RS06685	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FNS06_RS06700	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
FNS06_RS06720	COG2204	response regulator
FNS06_RS06730	COG1320	monovalent cation:proton antiporter activity
FNS06_RS06740	COG1863	multisubunit Na H antiporter MnhE subunit
FNS06_RS06745	COG0651	ATP synthesis coupled electron transport
FNS06_RS06750	COG1006	Multisubunit Na H antiporter MnhC subunit
FNS06_RS06755	COG2111	Na H antiporter
FNS06_RS06760	COG2111	Na H antiporter
FNS06_RS06760	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FNS06_RS06780	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
FNS06_RS06785	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FNS06_RS06790	COG1238	metal cluster binding
FNS06_RS06795	COG0405	Gamma-glutamyltransferase
FNS06_RS06820	COG1309	transcriptional regulator
FNS06_RS06825	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FNS06_RS06830	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
FNS06_RS06875	COG1366	Belongs to the anti-sigma-factor antagonist family
FNS06_RS06885	COG0436	Aminotransferase
FNS06_RS06900	COG1283	sodium-dependent phosphate transmembrane transporter activity
FNS06_RS06930	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
FNS06_RS06935	COG0511	ligase activity, forming carbon-carbon bonds
FNS06_RS06940	COG0439	Biotin carboxylase
FNS06_RS06945	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
FNS06_RS06950	COG1024	Enoyl-CoA hydratase
FNS06_RS06975	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FNS06_RS06985	COG0142	geranyltranstransferase activity
FNS06_RS07025	COG0438	transferase activity, transferring glycosyl groups
FNS06_RS07030	COG0463	Glycosyl transferase, family 2
FNS06_RS07045	COG1742	UPF0060 membrane protein
FNS06_RS07050	COG0574	Belongs to the PEP-utilizing enzyme family
FNS06_RS07050	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FNS06_RS07060	COG0752	glycyl-tRNA synthetase alpha subunit
FNS06_RS07120	COG2132	Multicopper oxidase
FNS06_RS07145	COG0559	Belongs to the binding-protein-dependent transport system permease family
FNS06_RS07160	COG0697	spore germination
FNS06_RS07260	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
FNS06_RS07270	COG1176	ABC-type spermidine putrescine transport system, permease component I
FNS06_RS07280	COG3842	ATPase activity
FNS06_RS07290	COG1280	lysine exporter protein (LysE YggA)
FNS06_RS07295	COG4651	solute:proton antiporter activity
FNS06_RS07295	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FNS06_RS07300	COG3706	GGDEF domain
FNS06_RS07305	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FNS06_RS07310	COG0318	PFAM AMP-dependent synthetase and ligase
FNS06_RS07330	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FNS06_RS07335	COG2345	Transcriptional regulator
FNS06_RS07360	COG1937	Protein conserved in bacteria
FNS06_RS07375	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FNS06_RS07385	COG0747	negative chemotaxis
FNS06_RS07390	COG0471	metal ion transport
FNS06_RS07390	COG3273	potassium ion transport
FNS06_RS07400	COG0725	ABC transporter, periplasmic molybdate-binding protein
FNS06_RS07405	COG4608	Belongs to the ABC transporter superfamily
FNS06_RS07415	COG0730	response to heat
FNS06_RS07420	COG0444	Belongs to the ABC transporter superfamily
FNS06_RS07465	COG4221	oxidoreductase activity
FNS06_RS07510	COG1278	Cold shock
FNS06_RS07530	COG0411	ABC transporter
FNS06_RS07575	COG1028	Short-chain dehydrogenase reductase Sdr
FNS06_RS07580	COG1802	Transcriptional regulator
FNS06_RS07590	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FNS06_RS07605	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
FNS06_RS07620	COG1607	acyl-coa hydrolase
FNS06_RS07635	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FNS06_RS07635	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
FNS06_RS07645	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
FNS06_RS07650	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
FNS06_RS07655	COG0154	amidase activity
FNS06_RS07670	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FNS06_RS07680	COG1132	(ABC) transporter
FNS06_RS07700	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
FNS06_RS07705	COG2271	Major facilitator Superfamily
FNS06_RS07730	COG0598	Magnesium transport protein CorA
FNS06_RS07770	COG1012	belongs to the aldehyde dehydrogenase family
FNS06_RS07780	COG0154	amidase activity
FNS06_RS07785	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FNS06_RS07820	COG0697	spore germination
FNS06_RS07825	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FNS06_RS07835	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FNS06_RS07845	COG4991	sh3 domain protein
FNS06_RS07850	COG0523	cobalamin synthesis protein
FNS06_RS07855	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FNS06_RS07860	COG1121	(ABC) transporter
FNS06_RS07865	COG0735	belongs to the Fur family
FNS06_RS07910	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FNS06_RS07920	COG0493	'glutamate synthase
FNS06_RS07925	COG0415	Belongs to the DNA photolyase family
FNS06_RS07965	COG1793	dna ligase
FNS06_RS07985	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
FNS06_RS07990	COG1088	dTDP-glucose 4,6-dehydratase activity
FNS06_RS08020	COG1028	Short-chain dehydrogenase reductase Sdr
FNS06_RS08045	COG0114	fumarate hydratase activity
FNS06_RS08055	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
FNS06_RS08065	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FNS06_RS08070	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
FNS06_RS08120	COG0484	heat shock protein binding
FNS06_RS08135	COG0300	oxidoreductase activity
FNS06_RS08150	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
FNS06_RS08175	COG0765	amino acid transport
FNS06_RS08180	COG0165	Argininosuccinate lyase
FNS06_RS08185	COG1126	abc transporter atp-binding protein
FNS06_RS08190	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FNS06_RS08195	COG0686	Belongs to the AlaDH PNT family
FNS06_RS08200	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FNS06_RS08215	COG3243	poly(R)-hydroxyalkanoic acid synthase
FNS06_RS08225	COG0028	Belongs to the TPP enzyme family
FNS06_RS08225	COG4032	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain
FNS06_RS08235	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
FNS06_RS08260	COG4566	intracellular signal transduction
FNS06_RS08265	COG0745	RESPONSE REGULATOR receiver
FNS06_RS08265	COG4566	intracellular signal transduction
FNS06_RS08270	COG4566	intracellular signal transduction
FNS06_RS08275	COG4191	Histidine kinase
FNS06_RS08280	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FNS06_RS08285	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
FNS06_RS08290	COG3842	ATPase activity
FNS06_RS08295	COG1176	ABC-type spermidine putrescine transport system, permease component I
FNS06_RS08300	COG1177	transmembrane transport
FNS06_RS08305	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FNS06_RS08335	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
FNS06_RS08345	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FNS06_RS08355	COG0318	PFAM AMP-dependent synthetase and ligase
FNS06_RS08365	COG3135	benzoate transporter
FNS06_RS08380	COG1960	acyl-CoA dehydrogenase activity
FNS06_RS08385	COG1028	Short-chain dehydrogenase reductase Sdr
FNS06_RS08385	COG0604	alcohol dehydrogenase
FNS06_RS08385	COG3321	synthase
FNS06_RS08390	COG1024	Enoyl-CoA hydratase
FNS06_RS08410	COG1960	acyl-CoA dehydrogenase activity
FNS06_RS08415	COG1024	Enoyl-CoA hydratase
FNS06_RS08430	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
FNS06_RS08465	COG0683	leucine binding
FNS06_RS08470	COG1309	transcriptional regulator
FNS06_RS08495	COG0625	glutathione transferase activity
FNS06_RS08505	COG0828	Belongs to the bacterial ribosomal protein bS21 family
FNS06_RS08515	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
FNS06_RS08575	COG2079	MmgE PrpD family protein
FNS06_RS08585	COG1177	transmembrane transport
FNS06_RS08590	COG1176	ABC-type spermidine putrescine transport system, permease component I
FNS06_RS08595	COG3842	ATPase activity
FNS06_RS08610	COG0583	DNA-binding transcription factor activity
FNS06_RS08620	COG1902	pentaerythritol trinitrate reductase activity
FNS06_RS08645	COG5002	protein histidine kinase activity
FNS06_RS08650	COG3920	Histidine kinase
FNS06_RS08655	COG0154	amidase activity
FNS06_RS08670	COG3964	amidohydrolase
FNS06_RS08680	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FNS06_RS08710	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FNS06_RS08715	COG2927	DNA polymerase III (CHI subunit)
FNS06_RS08720	COG0105	UTP biosynthetic process
FNS06_RS08730	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FNS06_RS08735	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
FNS06_RS08745	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FNS06_RS08750	COG0628	permease
FNS06_RS08755	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FNS06_RS08770	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
FNS06_RS08775	COG0248	Ppx GppA phosphatase
FNS06_RS08790	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
FNS06_RS08815	COG1960	acyl-CoA dehydrogenase activity
FNS06_RS08820	COG1960	acyl-CoA dehydrogenase activity
FNS06_RS08825	COG1960	acyl-CoA dehydrogenase activity
FNS06_RS08835	COG1028	Short-chain dehydrogenase reductase Sdr
FNS06_RS08850	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
FNS06_RS08860	COG0183	Belongs to the thiolase family
FNS06_RS08865	COG1250	3-hydroxyacyl-CoA dehydrogenase
FNS06_RS08865	COG1024	Enoyl-CoA hydratase
FNS06_RS08880	COG5001	Diguanylate cyclase
FNS06_RS08880	COG3300	MHYT domain
FNS06_RS08900	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FNS06_RS08915	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FNS06_RS08945	COG4774	siderophore transport
FNS06_RS08960	COG0733	neurotransmitter:sodium symporter activity
FNS06_RS08965	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FNS06_RS08975	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FNS06_RS09010	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
FNS06_RS09025	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
FNS06_RS09040	COG2226	methyltransferase
FNS06_RS09045	COG1802	Transcriptional regulator
FNS06_RS09060	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
FNS06_RS09085	COG1177	transmembrane transport
FNS06_RS09090	COG1176	ABC-type spermidine putrescine transport system, permease component I
FNS06_RS09100	COG3842	ATPase activity
FNS06_RS09105	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FNS06_RS09110	COG0583	DNA-binding transcription factor activity
FNS06_RS09140	COG1024	Enoyl-CoA hydratase
FNS06_RS09160	COG0842	Transport permease protein
FNS06_RS09165	COG1131	(ABC) transporter
FNS06_RS09180	COG2080	2 iron, 2 sulfur cluster binding
FNS06_RS09185	COG1529	Aldehyde oxidase and xanthine dehydrogenase
FNS06_RS09185	COG2010	Cytochrome c
FNS06_RS09195	COG0747	negative chemotaxis
FNS06_RS09205	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FNS06_RS09210	COG4172	Belongs to the ABC transporter superfamily
FNS06_RS09220	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
FNS06_RS09230	COG0438	transferase activity, transferring glycosyl groups
FNS06_RS09255	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FNS06_RS09260	COG0765	amino acid transport
FNS06_RS09265	COG0765	amino acid transport
FNS06_RS09275	COG0123	including yeast histone deacetylase and acetoin utilization protein
FNS06_RS09295	COG1181	Belongs to the D-alanine--D-alanine ligase family
FNS06_RS09300	COG0583	DNA-binding transcription factor activity
FNS06_RS09315	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FNS06_RS09350	COG5640	endopeptidase activity
FNS06_RS09360	COG0395	ABC-type sugar transport system, permease component
FNS06_RS09380	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FNS06_RS09385	COG4597	amino acid ABC transporter
FNS06_RS09390	COG0765	amino acid transport
FNS06_RS09395	COG1802	Transcriptional regulator
FNS06_RS09415	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
FNS06_RS09425	COG4948	Mandelate Racemase Muconate Lactonizing
FNS06_RS09450	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FNS06_RS09455	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
FNS06_RS09460	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FNS06_RS09465	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
FNS06_RS09490	COG0235	Class ii aldolase
FNS06_RS09495	COG0747	negative chemotaxis
FNS06_RS09505	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FNS06_RS09520	COG1562	ergosterol biosynthetic process
FNS06_RS09525	COG1562	ergosterol biosynthetic process
FNS06_RS09530	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
FNS06_RS09540	COG1752	Esterase of the alpha-beta hydrolase superfamily
FNS06_RS09545	COG1940	carbohydrate kinase activity
FNS06_RS09550	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FNS06_RS09600	COG0318	PFAM AMP-dependent synthetase and ligase
FNS06_RS09605	COG1573	uracil-dna glycosylase
FNS06_RS09620	COG1758	RNA polymerase activity
FNS06_RS09630	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
FNS06_RS09635	COG0736	holo-[acyl-carrier-protein] synthase activity
FNS06_RS09640	COG0681	Belongs to the peptidase S26 family
FNS06_RS09645	COG0571	ribonuclease III activity
FNS06_RS09650	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FNS06_RS09665	COG1175	transmembrane transport
FNS06_RS09670	COG0395	ABC-type sugar transport system, permease component
FNS06_RS09675	COG3842	ATPase activity
FNS06_RS09680	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
FNS06_RS09685	COG1381	Involved in DNA repair and RecF pathway recombination
FNS06_RS09690	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FNS06_RS09695	COG2885	chlorophyll binding
FNS06_RS09710	COG0028	Belongs to the TPP enzyme family
FNS06_RS09715	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FNS06_RS09725	COG0436	Aminotransferase
FNS06_RS09730	COG0784	Response regulator, receiver
FNS06_RS09730	COG2198	Histidine kinase
FNS06_RS09730	COG2205	protein histidine kinase activity
FNS06_RS09735	COG1335	isochorismatase
FNS06_RS09750	COG0534	Mate efflux family protein
FNS06_RS09755	COG1320	monovalent cation:proton antiporter activity
FNS06_RS09760	COG2212	antiporter activity
FNS06_RS09765	COG1863	multisubunit Na H antiporter MnhE subunit
FNS06_RS09770	COG0651	ATP synthesis coupled electron transport
FNS06_RS09775	COG1006	Multisubunit Na H antiporter MnhC subunit
FNS06_RS09780	COG2111	Na H antiporter
FNS06_RS09780	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FNS06_RS09785	COG0667	Aldo Keto reductase
FNS06_RS09795	COG4608	Belongs to the ABC transporter superfamily
FNS06_RS09800	COG0444	Belongs to the ABC transporter superfamily
FNS06_RS09815	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FNS06_RS09820	COG0601	transmembrane transport
FNS06_RS09840	COG1940	carbohydrate kinase activity
FNS06_RS09845	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FNS06_RS09850	COG0793	Belongs to the peptidase S41A family
FNS06_RS09855	COG0557	exoribonuclease II activity
FNS06_RS09860	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FNS06_RS09865	COG0758	DNA mediated transformation
FNS06_RS09870	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
FNS06_RS09900	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FNS06_RS09905	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FNS06_RS09910	COG0154	amidase activity
FNS06_RS09915	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FNS06_RS09920	COG0625	glutathione transferase activity
FNS06_RS09925	COG0625	glutathione transferase activity
FNS06_RS10000	COG1280	lysine exporter protein (LysE YggA)
FNS06_RS10005	COG2091	lysine biosynthetic process via aminoadipic acid
FNS06_RS10025	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
FNS06_RS10035	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FNS06_RS10050	COG4948	Mandelate Racemase Muconate Lactonizing
FNS06_RS10065	COG1176	ABC-type spermidine putrescine transport system, permease component I
FNS06_RS10100	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FNS06_RS10105	COG0601	transmembrane transport
FNS06_RS10110	COG0747	negative chemotaxis
FNS06_RS10120	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FNS06_RS10130	COG0444	Belongs to the ABC transporter superfamily
FNS06_RS10135	COG4948	Mandelate Racemase Muconate Lactonizing
FNS06_RS10145	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FNS06_RS10160	COG2814	Major facilitator Superfamily
FNS06_RS10185	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FNS06_RS10205	COG1216	Glycosyl transferase, family 2
FNS06_RS10240	COG0175	sulfate reduction
FNS06_RS10250	COG2204	response regulator
FNS06_RS10270	COG0405	Gamma-glutamyltransferase
FNS06_RS10280	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FNS06_RS10295	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
FNS06_RS10320	COG3550	peptidyl-serine autophosphorylation
FNS06_RS10330	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FNS06_RS10345	COG0006	proline dipeptidase activity
FNS06_RS10360	COG1176	ABC-type spermidine putrescine transport system, permease component I
FNS06_RS10365	COG1177	transmembrane transport
FNS06_RS10375	COG0473	3-isopropylmalate dehydrogenase activity
FNS06_RS10380	COG0066	3-isopropylmalate dehydratase activity
FNS06_RS10385	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FNS06_RS10390	COG0784	Response regulator, receiver
FNS06_RS10395	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FNS06_RS10400	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FNS06_RS10410	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FNS06_RS10420	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
FNS06_RS10445	COG0784	Response regulator, receiver
FNS06_RS10445	COG4191	Histidine kinase
FNS06_RS10460	COG3616	Alanine racemase, N-terminal domain
FNS06_RS10470	COG0765	amino acid transport
FNS06_RS10475	COG0765	amino acid transport
FNS06_RS10490	COG1335	isochorismatase
FNS06_RS10495	COG2226	methyltransferase
FNS06_RS10510	COG1028	Short-chain dehydrogenase reductase Sdr
FNS06_RS10535	COG1028	Short-chain dehydrogenase reductase Sdr
FNS06_RS10550	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FNS06_RS10565	COG0747	negative chemotaxis
FNS06_RS10570	COG0747	negative chemotaxis
FNS06_RS10575	COG0601	transmembrane transport
FNS06_RS10580	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FNS06_RS10585	COG0444	Belongs to the ABC transporter superfamily
FNS06_RS10590	COG4608	Belongs to the ABC transporter superfamily
FNS06_RS10615	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FNS06_RS10620	COG0747	negative chemotaxis
FNS06_RS10630	COG1609	Transcriptional regulator
FNS06_RS10665	COG0784	Response regulator, receiver
FNS06_RS10665	COG2198	Histidine kinase
FNS06_RS10665	COG2205	protein histidine kinase activity
FNS06_RS10680	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FNS06_RS10685	COG1177	transmembrane transport
FNS06_RS10690	COG1176	ABC-type spermidine putrescine transport system, permease component I
FNS06_RS10700	COG0434	BtpA family
FNS06_RS10705	COG1070	Carbohydrate kinase
FNS06_RS10750	COG3842	ATPase activity
FNS06_RS10755	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FNS06_RS10765	COG2079	MmgE PrpD family protein
FNS06_RS10775	COG1877	trehalose-phosphatase activity
FNS06_RS10790	COG3128	pkhd-type hydroxylase
FNS06_RS10805	COG3180	Ammonia monooxygenase
FNS06_RS10810	COG2988	succinylglutamate desuccinylase activity
FNS06_RS10815	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FNS06_RS10820	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FNS06_RS10830	COG0601	transmembrane transport
FNS06_RS10840	COG0444	Belongs to the ABC transporter superfamily
FNS06_RS10845	COG4608	Belongs to the ABC transporter superfamily
FNS06_RS10890	COG0746	molybdenum cofactor guanylyltransferase activity
FNS06_RS10905	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FNS06_RS10910	COG4948	Mandelate Racemase Muconate Lactonizing
FNS06_RS10925	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
FNS06_RS10925	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
FNS06_RS10930	COG1024	Enoyl-CoA hydratase
FNS06_RS10935	COG0045	succinate-CoA ligase (ADP-forming) activity
FNS06_RS10935	COG1042	CoA-binding domain protein
FNS06_RS10935	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FNS06_RS10945	COG1960	acyl-CoA dehydrogenase activity
FNS06_RS10950	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
FNS06_RS10965	COG2154	pterin-4-alpha-carbinolamine dehydratase
FNS06_RS10995	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FNS06_RS11000	COG1178	ABC-type Fe3 transport system permease component
FNS06_RS11015	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
FNS06_RS11060	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FNS06_RS11065	COG2814	Major facilitator Superfamily
FNS06_RS11070	COG2814	Major facilitator Superfamily
FNS06_RS11075	COG3135	benzoate transporter
FNS06_RS11080	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FNS06_RS11140	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FNS06_RS11155	COG3145	DNA-N1-methyladenine dioxygenase activity
FNS06_RS11190	COG0587	DNA-directed DNA polymerase activity
FNS06_RS11240	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FNS06_RS11245	COG2175	clavaminate synthase activity
FNS06_RS11255	COG0765	amino acid transport
FNS06_RS11260	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FNS06_RS11265	COG4638	Rieske (2fe-2S)
FNS06_RS11275	COG1309	transcriptional regulator
FNS06_RS11315	COG1529	Aldehyde oxidase and xanthine dehydrogenase
FNS06_RS11315	COG2010	Cytochrome c
FNS06_RS11325	COG0446	pyridine nucleotide-disulphide oxidoreductase
FNS06_RS11345	COG3258	Cytochrome c
FNS06_RS11350	COG0583	DNA-binding transcription factor activity
FNS06_RS11360	COG0747	negative chemotaxis
FNS06_RS11395	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FNS06_RS11400	COG1518	maintenance of DNA repeat elements
FNS06_RS11415	COG1857	crispr-associated protein
FNS06_RS11430	COG1203	CRISPR-associated helicase, Cas3
FNS06_RS11450	COG2175	clavaminate synthase activity
FNS06_RS11455	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FNS06_RS11460	COG1295	ribonuclease BN
FNS06_RS11475	COG4191	Histidine kinase
FNS06_RS11485	COG4566	intracellular signal transduction
FNS06_RS11490	COG0602	queuosine metabolic process
FNS06_RS11510	COG0564	pseudouridine synthase activity
FNS06_RS11525	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FNS06_RS11545	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FNS06_RS11560	COG0745	RESPONSE REGULATOR receiver
FNS06_RS11575	COG1024	Enoyl-CoA hydratase
FNS06_RS11595	COG0318	PFAM AMP-dependent synthetase and ligase
FNS06_RS11610	COG0179	Fumarylacetoacetate (FAA) hydrolase
FNS06_RS11620	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FNS06_RS11625	COG1309	transcriptional regulator
FNS06_RS11640	COG1960	acyl-CoA dehydrogenase activity
FNS06_RS11645	COG1028	Short-chain dehydrogenase reductase Sdr
FNS06_RS11660	COG2816	NAD+ diphosphatase activity
FNS06_RS11680	COG2030	dehydratase
FNS06_RS11685	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
FNS06_RS11690	COG3265	gluconokinase activity
FNS06_RS11695	COG0753	catalase activity
FNS06_RS11715	COG2358	TRAP transporter, solute receptor (TAXI family
FNS06_RS11720	COG0739	heme binding
FNS06_RS11735	COG0741	lytic transglycosylase activity
FNS06_RS11740	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FNS06_RS11745	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FNS06_RS11750	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
FNS06_RS11750	COG3608	succinylglutamate desuccinylase aspartoacylase
FNS06_RS11805	COG0154	amidase activity
FNS06_RS11810	COG0633	Ferredoxin
FNS06_RS11845	COG0586	Pfam SNARE associated Golgi protein
FNS06_RS11860	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FNS06_RS11865	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FNS06_RS11870	COG1116	anion transmembrane transporter activity
FNS06_RS11900	COG0626	cystathionine gamma-synthase activity
FNS06_RS11920	COG0242	peptide deformylase activity
FNS06_RS11925	COG0579	oxidoreductase
FNS06_RS11935	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
FNS06_RS11955	COG0333	Belongs to the bacterial ribosomal protein bL32 family
FNS06_RS11960	COG0416	fatty acid biosynthetic process
FNS06_RS11965	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FNS06_RS11970	COG0776	regulation of translation
FNS06_RS11990	COG2945	thiolester hydrolase activity
FNS06_RS11995	COG1045	serine acetyltransferase
FNS06_RS12015	COG0822	iron-sulfur transferase activity
FNS06_RS12020	COG0316	Belongs to the HesB IscA family
FNS06_RS12025	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
FNS06_RS12030	COG0443	Heat shock 70 kDa protein
FNS06_RS12045	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
FNS06_RS12050	COG0482	sulfurtransferase activity
FNS06_RS12060	COG5001	Diguanylate cyclase
FNS06_RS12060	COG3447	MASE1 domain protein
FNS06_RS12060	COG5002	protein histidine kinase activity
FNS06_RS12065	COG0800	Aldolase
FNS06_RS12070	COG3734	2-keto-3-deoxy-galactonokinase
FNS06_RS12080	COG0625	glutathione transferase activity
FNS06_RS12085	COG0717	Belongs to the dCTP deaminase family
FNS06_RS12090	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FNS06_RS12105	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FNS06_RS12110	COG5328	Belongs to the UPF0262 family
FNS06_RS12115	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FNS06_RS12150	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
FNS06_RS12205	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FNS06_RS12210	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
FNS06_RS12225	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FNS06_RS12230	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
FNS06_RS12235	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FNS06_RS12240	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FNS06_RS12245	COG0154	amidase activity
FNS06_RS12250	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FNS06_RS12260	COG0489	protein tyrosine kinase activity
FNS06_RS12265	COG0330	HflC and HflK could
FNS06_RS12270	COG0330	HflC and HflK could
FNS06_RS12285	COG0560	Phosphoserine phosphatase
FNS06_RS12285	COG3830	Belongs to the UPF0237 family
FNS06_RS12290	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
FNS06_RS12295	COG0028	Belongs to the TPP enzyme family
FNS06_RS12300	COG0440	acetolactate synthase activity
FNS06_RS12350	COG2205	protein histidine kinase activity
FNS06_RS12360	COG5507	3-demethylubiquinone-9 3-methyltransferase
FNS06_RS12370	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
FNS06_RS12375	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FNS06_RS12390	COG0071	Belongs to the small heat shock protein (HSP20) family
FNS06_RS12420	COG4336	lyase activity
FNS06_RS12430	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FNS06_RS12445	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FNS06_RS12480	COG0625	glutathione transferase activity
FNS06_RS12495	COG0745	RESPONSE REGULATOR receiver
FNS06_RS12505	COG0405	Gamma-glutamyltransferase
FNS06_RS12510	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
FNS06_RS12520	COG4948	Mandelate Racemase Muconate Lactonizing
FNS06_RS12545	COG5002	protein histidine kinase activity
FNS06_RS12555	COG0667	Aldo Keto reductase
FNS06_RS12565	COG1960	acyl-CoA dehydrogenase activity
FNS06_RS12595	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FNS06_RS12665	COG4191	Histidine kinase
FNS06_RS12665	COG0784	Response regulator, receiver
FNS06_RS12675	COG1132	(ABC) transporter
FNS06_RS12690	COG2119	membrane
FNS06_RS12705	COG1181	Belongs to the D-alanine--D-alanine ligase family
FNS06_RS12720	COG2084	Dehydrogenase
FNS06_RS12735	COG0395	ABC-type sugar transport system, permease component
FNS06_RS12745	COG2079	MmgE PrpD family protein
FNS06_RS12760	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FNS06_RS12765	COG1802	Transcriptional regulator
FNS06_RS12780	COG0778	Nitroreductase
FNS06_RS12805	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FNS06_RS12835	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FNS06_RS12845	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FNS06_RS12845	COG0519	Catalyzes the synthesis of GMP from XMP
FNS06_RS12860	COG3842	ATPase activity
FNS06_RS12865	COG1176	ABC-type spermidine putrescine transport system, permease component I
FNS06_RS12870	COG1177	transmembrane transport
FNS06_RS12910	COG1393	Belongs to the ArsC family
FNS06_RS12915	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FNS06_RS12935	COG2080	2 iron, 2 sulfur cluster binding
FNS06_RS12940	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
FNS06_RS12945	COG1529	Aldehyde oxidase and xanthine dehydrogenase
FNS06_RS12960	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FNS06_RS12965	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
FNS06_RS12970	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
FNS06_RS12975	COG1505	serine-type exopeptidase activity
FNS06_RS12980	COG1028	Short-chain dehydrogenase reductase Sdr
FNS06_RS12985	COG1309	transcriptional regulator
FNS06_RS13000	COG1366	Belongs to the anti-sigma-factor antagonist family
FNS06_RS13005	COG1366	Belongs to the anti-sigma-factor antagonist family
FNS06_RS13010	COG2172	sigma factor antagonist activity
FNS06_RS13020	COG2205	protein histidine kinase activity
FNS06_RS13020	COG2202	Pas domain
FNS06_RS13030	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FNS06_RS13030	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FNS06_RS13040	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FNS06_RS13045	COG1028	Short-chain dehydrogenase reductase Sdr
FNS06_RS13060	COG1335	isochorismatase
FNS06_RS13065	COG0673	inositol 2-dehydrogenase activity
FNS06_RS13070	COG0129	dihydroxy-acid dehydratase activity
FNS06_RS13095	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FNS06_RS13110	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FNS06_RS13125	COG0392	lysyltransferase activity
FNS06_RS13135	COG1228	amidohydrolase
FNS06_RS13145	COG1414	Transcriptional regulator
FNS06_RS13155	COG4177	L-phenylalanine transmembrane transporter activity
FNS06_RS13160	COG0411	ABC transporter
FNS06_RS13190	COG1132	(ABC) transporter
FNS06_RS13200	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FNS06_RS13210	COG0765	amino acid transport
FNS06_RS13215	COG1126	abc transporter atp-binding protein
FNS06_RS13220	COG0235	Class ii aldolase
FNS06_RS13225	COG3395	kinase activity
FNS06_RS13235	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FNS06_RS13240	COG2358	TRAP transporter, solute receptor (TAXI family
FNS06_RS13250	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FNS06_RS13260	COG2022	thiamine diphosphate biosynthetic process
FNS06_RS13280	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FNS06_RS13285	COG1160	GTP binding
FNS06_RS13295	COG1028	Short-chain dehydrogenase reductase Sdr
FNS06_RS13300	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
FNS06_RS13305	COG1286	toxin biosynthetic process
FNS06_RS13315	COG1127	ABC transporter
FNS06_RS13320	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FNS06_RS13325	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FNS06_RS13330	COG0305	Participates in initiation and elongation during chromosome replication
FNS06_RS13335	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FNS06_RS13355	COG1657	PFAM Prenyltransferase squalene oxidase
FNS06_RS13370	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
FNS06_RS13380	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
FNS06_RS13395	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FNS06_RS13400	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FNS06_RS13410	COG1561	YicC-like family, N-terminal region
FNS06_RS13430	COG0488	(ABC) transporter
FNS06_RS13435	COG0251	oxidation-reduction process
FNS06_RS13495	COG0673	inositol 2-dehydrogenase activity
FNS06_RS13500	COG1082	Xylose isomerase domain protein TIM barrel
FNS06_RS13515	COG0473	3-isopropylmalate dehydrogenase activity
FNS06_RS13525	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FNS06_RS13540	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FNS06_RS13545	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FNS06_RS13560	COG0667	Aldo Keto reductase
FNS06_RS13565	COG1028	Short-chain dehydrogenase reductase Sdr
FNS06_RS13585	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FNS06_RS13590	COG1280	lysine exporter protein (LysE YggA)
FNS06_RS13595	COG0386	Belongs to the glutathione peroxidase family
FNS06_RS13620	COG0596	Alpha beta hydrolase
FNS06_RS13635	COG3454	Phosphonate metabolism
FNS06_RS13640	COG4778	phosphonate C-P lyase system protein PhnL
FNS06_RS13645	COG4107	phosphonate C-P lyase system protein PhnK
FNS06_RS13650	COG3627	carbon phosphorus lyase activity
FNS06_RS13655	COG3626	phosphonate metabolism
FNS06_RS13660	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
FNS06_RS13665	COG3624	Phosphonate C-P lyase system protein PhnG
FNS06_RS13670	COG2188	Transcriptional regulator
FNS06_RS13675	COG3454	Phosphonate metabolism
FNS06_RS13680	COG3971	2-oxopent-4-enoate hydratase activity
FNS06_RS13690	COG2873	o-acetylhomoserine
FNS06_RS13695	COG1832	CoA-binding protein
FNS06_RS13700	COG1024	Enoyl-CoA hydratase
FNS06_RS13715	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
FNS06_RS13720	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
FNS06_RS13730	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
FNS06_RS13740	COG3243	poly(R)-hydroxyalkanoic acid synthase
FNS06_RS13755	COG1494	fructose-1,6-bisphosphatase
FNS06_RS13760	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FNS06_RS13775	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
FNS06_RS13780	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FNS06_RS13800	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FNS06_RS13820	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
FNS06_RS13845	COG1609	Transcriptional regulator
FNS06_RS13860	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
FNS06_RS13865	COG1028	Short-chain dehydrogenase reductase Sdr
FNS06_RS13870	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
FNS06_RS13870	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
FNS06_RS13885	COG1309	transcriptional regulator
FNS06_RS13895	COG1131	(ABC) transporter
FNS06_RS13900	COG0842	Transport permease protein
FNS06_RS13925	COG0544	peptidyl-prolyl cis-trans isomerase activity
FNS06_RS13945	COG0776	regulation of translation
FNS06_RS13955	COG4993	Dehydrogenase
FNS06_RS14080	COG4227	nucleotidyltransferase activity
FNS06_RS14145	COG0535	radical SAM domain protein
FNS06_RS14150	COG0535	radical SAM domain protein
FNS06_RS14155	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
FNS06_RS14160	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
FNS06_RS14205	COG0649	NAD binding
FNS06_RS14210	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
FNS06_RS14220	COG1034	ATP synthesis coupled electron transport
FNS06_RS14225	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
FNS06_RS14230	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FNS06_RS14240	COG0713	ATP synthesis coupled electron transport
FNS06_RS14255	COG1007	ATP synthesis coupled electron transport
FNS06_RS14275	COG0346	lactoylglutathione lyase activity
FNS06_RS14285	COG0519	Catalyzes the synthesis of GMP from XMP
FNS06_RS14290	COG1609	Transcriptional regulator
FNS06_RS14300	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
FNS06_RS14305	COG1177	transmembrane transport
FNS06_RS14310	COG3842	ATPase activity
FNS06_RS14325	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
FNS06_RS14335	COG2252	PERMEase
FNS06_RS14340	COG0625	glutathione transferase activity
FNS06_RS14345	COG0442	prolyl-tRNA aminoacylation
FNS06_RS14375	COG0052	Belongs to the universal ribosomal protein uS2 family
FNS06_RS14390	COG0233	cytoplasmic translational termination
FNS06_RS14395	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FNS06_RS14405	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
FNS06_RS14410	COG0750	zinc metalloprotease
FNS06_RS14415	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FNS06_RS14425	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FNS06_RS14435	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FNS06_RS14440	COG3494	Protein of unknown function (DUF1009)
FNS06_RS14445	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FNS06_RS14450	COG2223	nitrite transmembrane transporter activity
FNS06_RS14465	COG0346	lactoylglutathione lyase activity
FNS06_RS14475	COG0372	Belongs to the citrate synthase family
FNS06_RS14480	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FNS06_RS14490	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FNS06_RS14500	COG0303	'Molybdopterin
FNS06_RS14505	COG0315	cyclic pyranopterin monophosphate synthase activity
FNS06_RS14515	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FNS06_RS14525	COG2861	carbohydrate metabolic process
FNS06_RS14530	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FNS06_RS14535	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FNS06_RS14555	COG0584	glycerophosphoryl diester phosphodiesterase
FNS06_RS14570	COG2877	3-deoxy-8-phosphooctulonate synthase activity
FNS06_RS14580	COG0148	phosphopyruvate hydratase activity
FNS06_RS14590	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FNS06_RS14595	COG0022	dehydrogenase e1 component
FNS06_RS14595	COG0508	dehydrogenase complex catalyzes the overall conversion of
FNS06_RS14600	COG0508	dehydrogenase complex catalyzes the overall conversion of
FNS06_RS14605	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FNS06_RS14610	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
FNS06_RS14615	COG2867	negative regulation of translational initiation
FNS06_RS14620	COG1546	Belongs to the CinA family
FNS06_RS14620	COG1058	Belongs to the CinA family
FNS06_RS14660	COG2204	response regulator
FNS06_RS14665	COG0569	domain protein
FNS06_RS14670	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FNS06_RS14675	COG0546	phosphoglycolate phosphatase activity
FNS06_RS14680	COG1923	regulation of RNA biosynthetic process
FNS06_RS14685	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FNS06_RS14690	COG0483	inositol monophosphate 1-phosphatase activity
FNS06_RS14700	COG0456	acetyltransferase
FNS06_RS14705	COG4221	oxidoreductase activity
FNS06_RS14710	COG3956	TIGRFAM MazG family protein
FNS06_RS14715	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
FNS06_RS14715	COG0321	lipoyl(octanoyl) transferase activity
FNS06_RS14720	COG0084	hydrolase, TatD family'
FNS06_RS14735	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
FNS06_RS14740	COG1686	Belongs to the peptidase S11 family
FNS06_RS14745	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
FNS06_RS14750	COG2951	lytic endotransglycosylase activity
FNS06_RS14770	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FNS06_RS14775	COG3932	Exopolysaccharide synthesis, ExoD
FNS06_RS14815	COG0531	amino acid
FNS06_RS14820	COG2070	2-Nitropropane dioxygenase
FNS06_RS14825	COG4943	cyclic-guanylate-specific phosphodiesterase activity
FNS06_RS14835	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FNS06_RS14845	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FNS06_RS14850	COG1309	transcriptional regulator
FNS06_RS14860	COG4336	lyase activity
FNS06_RS14890	COG3181	Tripartite tricarboxylate transporter family receptor
FNS06_RS14915	COG0235	Class ii aldolase
FNS06_RS14920	COG0154	amidase activity
FNS06_RS14930	COG3842	ATPase activity
FNS06_RS14945	COG1178	ABC-type Fe3 transport system permease component
FNS06_RS14950	COG1473	amidohydrolase
FNS06_RS14955	COG2235	arginine
FNS06_RS14960	COG2442	InterPro IPR007367
FNS06_RS14975	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FNS06_RS15000	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FNS06_RS15015	COG0187	DNA topoisomerase II activity
FNS06_RS15020	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FNS06_RS15030	COG0513	Belongs to the DEAD box helicase family
FNS06_RS15055	COG0411	ABC transporter
FNS06_RS15080	COG1454	alcohol dehydrogenase
FNS06_RS15085	COG0183	Belongs to the thiolase family
FNS06_RS15090	COG2358	TRAP transporter, solute receptor (TAXI family
FNS06_RS15105	COG0243	molybdopterin cofactor binding
FNS06_RS15110	COG0437	4 iron, 4 sulfur cluster binding
FNS06_RS15115	COG3302	dmso reductase anchor subunit
FNS06_RS15215	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
FNS06_RS15220	COG0559	Belongs to the binding-protein-dependent transport system permease family
FNS06_RS15235	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FNS06_RS15240	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FNS06_RS15260	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FNS06_RS15280	COG0129	dihydroxy-acid dehydratase activity
FNS06_RS15285	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FNS06_RS15300	COG4948	Mandelate Racemase Muconate Lactonizing
FNS06_RS15305	COG0395	ABC-type sugar transport system, permease component
FNS06_RS15310	COG1175	transmembrane transport
FNS06_RS15320	COG3842	ATPase activity
FNS06_RS15325	COG3622	Belongs to the hyi family
FNS06_RS15330	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FNS06_RS15345	COG1028	Short-chain dehydrogenase reductase Sdr
FNS06_RS15350	COG2721	sulfolactate sulfo-lyase activity
FNS06_RS15360	COG1028	Short-chain dehydrogenase reductase Sdr
FNS06_RS15375	COG1595	DNA-templated transcription, initiation
FNS06_RS15380	COG3712	iron ion homeostasis
FNS06_RS15385	COG4774	siderophore transport
FNS06_RS15405	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
FNS06_RS15410	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FNS06_RS15430	COG0778	Nitroreductase
FNS06_RS15465	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
FNS06_RS15470	COG1069	ribulokinase activity
FNS06_RS15475	COG1028	Short-chain dehydrogenase reductase Sdr
FNS06_RS15490	COG3813	Protein conserved in bacteria
FNS06_RS15495	COG1028	Short-chain dehydrogenase reductase Sdr
FNS06_RS15520	COG3768	UPF0283 membrane protein
FNS06_RS15525	COG3106	COG3106 Predicted ATPase
FNS06_RS15530	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FNS06_RS15545	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FNS06_RS15560	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FNS06_RS15565	COG1984	allophanate hydrolase subunit 2
FNS06_RS15570	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
FNS06_RS15595	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
FNS06_RS15600	COG2814	Major facilitator Superfamily
FNS06_RS15605	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
FNS06_RS15615	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
FNS06_RS15620	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FNS06_RS15620	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FNS06_RS15630	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FNS06_RS15630	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FNS06_RS15635	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
FNS06_RS15645	COG0698	ribose 5-phosphate isomerase
FNS06_RS15650	COG4957	zinc ion binding
FNS06_RS15685	COG1960	acyl-CoA dehydrogenase activity
FNS06_RS15720	COG1024	Enoyl-CoA hydratase
FNS06_RS15725	COG0113	porphobilinogen synthase activity
FNS06_RS15730	COG1846	Transcriptional regulator
FNS06_RS15730	COG0456	acetyltransferase
FNS06_RS15745	COG5001	Diguanylate cyclase
FNS06_RS15745	COG3706	GGDEF domain
FNS06_RS15745	COG2203	Gaf domain
FNS06_RS15745	COG4251	negative regulation of phosphorylation
FNS06_RS15760	COG1012	belongs to the aldehyde dehydrogenase family
FNS06_RS15770	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FNS06_RS15775	COG0784	Response regulator, receiver
FNS06_RS15775	COG4191	Histidine kinase
FNS06_RS15800	COG2847	Copper chaperone PCu(A)C
FNS06_RS15805	COG0523	cobalamin synthesis protein
FNS06_RS15815	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FNS06_RS15820	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FNS06_RS15850	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FNS06_RS15855	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
FNS06_RS15865	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
FNS06_RS15880	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FNS06_RS15885	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
FNS06_RS15895	COG2358	TRAP transporter, solute receptor (TAXI family
FNS06_RS15910	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FNS06_RS15925	COG0534	Mate efflux family protein
FNS06_RS15945	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FNS06_RS15970	COG0538	isocitrate dehydrogenase activity
FNS06_RS15980	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
FNS06_RS16015	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FNS06_RS16020	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FNS06_RS16025	COG1840	ABC-type Fe3 transport system, periplasmic component
FNS06_RS16030	COG3842	ATPase activity
FNS06_RS16040	COG1764	response to oxidative stress
FNS06_RS16065	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FNS06_RS16075	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
FNS06_RS16095	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FNS06_RS16105	COG3960	tartronate-semialdehyde synthase activity
FNS06_RS16140	COG0625	glutathione transferase activity
FNS06_RS16150	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FNS06_RS16155	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FNS06_RS16170	COG0154	amidase activity
FNS06_RS16185	COG1840	ABC-type Fe3 transport system, periplasmic component
FNS06_RS16195	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FNS06_RS16200	COG1960	acyl-CoA dehydrogenase activity
FNS06_RS16220	COG0842	Transport permease protein
FNS06_RS16225	COG1129	ABC transporter
FNS06_RS16225	COG0842	Transport permease protein
FNS06_RS16230	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FNS06_RS16235	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FNS06_RS16245	COG2843	Capsule synthesis protein
FNS06_RS16255	COG2267	carboxylic ester hydrolase activity
FNS06_RS16270	COG2032	superoxide dismutase activity
FNS06_RS16275	COG0697	spore germination
FNS06_RS16325	COG0596	Alpha beta hydrolase
FNS06_RS16330	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FNS06_RS16335	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FNS06_RS16370	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FNS06_RS16415	COG0129	dihydroxy-acid dehydratase activity
FNS06_RS16425	COG0671	phosphoesterase, PA-phosphatase related
FNS06_RS16440	COG2943	transferase activity, transferring hexosyl groups
FNS06_RS16465	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FNS06_RS16465	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FNS06_RS16470	COG3639	organic phosphonate transmembrane transporter activity
FNS06_RS16475	COG3639	organic phosphonate transmembrane transporter activity
FNS06_RS16485	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
FNS06_RS16490	COG0784	Response regulator, receiver
FNS06_RS16490	COG4191	Histidine kinase
FNS06_RS16495	COG0784	Response regulator, receiver
FNS06_RS16500	COG4251	negative regulation of phosphorylation
FNS06_RS16520	COG1178	ABC-type Fe3 transport system permease component
FNS06_RS16525	COG1176	ABC-type spermidine putrescine transport system, permease component I
FNS06_RS16535	COG3842	ATPase activity
FNS06_RS16545	COG1028	Short-chain dehydrogenase reductase Sdr
FNS06_RS16560	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FNS06_RS16590	COG1902	pentaerythritol trinitrate reductase activity
FNS06_RS16605	COG3842	ATPase activity
FNS06_RS16610	COG1902	pentaerythritol trinitrate reductase activity
FNS06_RS16615	COG0251	oxidation-reduction process
FNS06_RS16650	COG0559	Belongs to the binding-protein-dependent transport system permease family
FNS06_RS16670	COG1028	Short-chain dehydrogenase reductase Sdr
FNS06_RS16690	COG4095	Psort location CytoplasmicMembrane, score
FNS06_RS16695	COG0784	Response regulator, receiver
FNS06_RS16710	COG3239	Fatty acid desaturase
FNS06_RS16720	COG0438	transferase activity, transferring glycosyl groups
FNS06_RS16725	COG1482	cell wall glycoprotein biosynthetic process
FNS06_RS16730	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FNS06_RS16740	COG1396	sequence-specific DNA binding
FNS06_RS16750	COG3842	ATPase activity
FNS06_RS16755	COG1176	ABC-type spermidine putrescine transport system, permease component I
FNS06_RS16760	COG1178	ABC-type Fe3 transport system permease component
FNS06_RS16765	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FNS06_RS16770	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FNS06_RS16800	COG0804	urea catabolic process
FNS06_RS16805	COG0523	cobalamin synthesis protein
FNS06_RS16810	COG0745	RESPONSE REGULATOR receiver
FNS06_RS16820	COG0510	thiamine kinase activity
FNS06_RS16825	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FNS06_RS16840	COG4948	Mandelate Racemase Muconate Lactonizing
FNS06_RS16880	COG2217	Heavy metal translocating P-type atpase
FNS06_RS16885	COG1028	Short-chain dehydrogenase reductase Sdr
FNS06_RS16900	COG0523	cobalamin synthesis protein
FNS06_RS16925	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
FNS06_RS16930	COG0583	DNA-binding transcription factor activity
FNS06_RS16935	COG0251	oxidation-reduction process
FNS06_RS16960	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FNS06_RS16970	COG0411	ABC transporter
FNS06_RS17010	COG1028	Short-chain dehydrogenase reductase Sdr
FNS06_RS17025	COG1733	regulation of RNA biosynthetic process
FNS06_RS17040	COG0308	aminopeptidase N
FNS06_RS17055	COG0243	molybdopterin cofactor binding
FNS06_RS17080	COG1643	Atp-dependent helicase
FNS06_RS17110	COG1393	Belongs to the ArsC family
FNS06_RS17120	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FNS06_RS17135	COG0625	glutathione transferase activity
FNS06_RS17140	COG0625	glutathione transferase activity
FNS06_RS17165	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FNS06_RS17170	COG1595	DNA-templated transcription, initiation
FNS06_RS17175	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FNS06_RS17185	COG0640	Transcriptional regulator
FNS06_RS17190	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FNS06_RS17205	COG0697	spore germination
FNS06_RS17210	COG0436	Aminotransferase
FNS06_RS17230	COG4977	sequence-specific DNA binding
FNS06_RS17245	COG0488	(ABC) transporter
FNS06_RS17250	COG4691	Plasmid stability protein
FNS06_RS17255	COG1487	ribonuclease activity
FNS06_RS17280	COG0519	Catalyzes the synthesis of GMP from XMP
FNS06_RS17280	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FNS06_RS17290	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FNS06_RS17290	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FNS06_RS17300	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
FNS06_RS17345	COG1028	Short-chain dehydrogenase reductase Sdr
FNS06_RS17350	COG1850	ribulose-bisphosphate carboxylase activity
FNS06_RS17370	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FNS06_RS17380	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FNS06_RS17385	COG1278	Cold shock
FNS06_RS17395	COG1285	pathogenesis
FNS06_RS17415	COG2860	membrane
FNS06_RS17435	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
FNS06_RS17445	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
FNS06_RS17455	COG0513	Belongs to the DEAD box helicase family
FNS06_RS17475	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FNS06_RS17495	COG1175	transmembrane transport
FNS06_RS17515	COG0179	Fumarylacetoacetate (FAA) hydrolase
FNS06_RS17530	COG0395	ABC-type sugar transport system, permease component
FNS06_RS17535	COG1175	transmembrane transport
FNS06_RS17545	COG2084	Dehydrogenase
FNS06_RS17560	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FNS06_RS17565	COG0583	DNA-binding transcription factor activity
FNS06_RS17615	COG3311	Transcriptional regulator
FNS06_RS17665	COG1028	Short-chain dehydrogenase reductase Sdr
FNS06_RS17675	COG2353	YceI-like domain
FNS06_RS17690	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FNS06_RS17700	COG1902	pentaerythritol trinitrate reductase activity
FNS06_RS17730	COG0366	Alpha amylase catalytic
FNS06_RS17740	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
FNS06_RS17750	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
FNS06_RS17780	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FNS06_RS17785	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FNS06_RS17790	COG0047	phosphoribosylformylglycinamidine synthase activity
FNS06_RS17795	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FNS06_RS17805	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
FNS06_RS17810	COG2962	Rard protein
FNS06_RS17825	COG1280	lysine exporter protein (LysE YggA)
FNS06_RS17835	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
FNS06_RS17875	COG1058	Belongs to the CinA family
FNS06_RS17875	COG1546	Belongs to the CinA family
FNS06_RS17880	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FNS06_RS17890	COG0024	Methionine aminopeptidase
FNS06_RS17895	COG2003	Belongs to the UPF0758 family
FNS06_RS17920	COG0583	DNA-binding transcription factor activity
FNS06_RS17945	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
FNS06_RS17985	COG2076	Multidrug Resistance protein
FNS06_RS17990	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FNS06_RS17995	COG0625	glutathione transferase activity
FNS06_RS18020	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FNS06_RS18025	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FNS06_RS18035	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FNS06_RS18040	COG1278	Cold shock
FNS06_RS18060	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
FNS06_RS18080	COG2226	methyltransferase
FNS06_RS18085	COG2135	peptidase activity
FNS06_RS18180	COG0778	Nitroreductase
FNS06_RS18190	COG4191	Histidine kinase
FNS06_RS18190	COG0784	Response regulator, receiver
FNS06_RS18200	COG0747	negative chemotaxis
FNS06_RS18205	COG0747	negative chemotaxis
FNS06_RS18210	COG0747	negative chemotaxis
FNS06_RS18220	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FNS06_RS18230	COG0747	negative chemotaxis
FNS06_RS18235	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FNS06_RS18240	COG0747	negative chemotaxis
FNS06_RS18245	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FNS06_RS18250	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FNS06_RS18255	COG0747	negative chemotaxis
FNS06_RS18260	COG0747	negative chemotaxis
FNS06_RS18265	COG0601	transmembrane transport
FNS06_RS18270	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FNS06_RS18275	COG4172	Belongs to the ABC transporter superfamily
FNS06_RS18285	COG1396	sequence-specific DNA binding
FNS06_RS18290	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
FNS06_RS18295	COG0251	oxidation-reduction process
FNS06_RS18315	COG2186	Transcriptional regulator
FNS06_RS18325	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FNS06_RS18330	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FNS06_RS18340	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
FNS06_RS18350	COG1012	belongs to the aldehyde dehydrogenase family
FNS06_RS18370	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
FNS06_RS18385	COG2515	1-aminocyclopropane-1-carboxylate deaminase
FNS06_RS18390	COG1960	acyl-CoA dehydrogenase activity
FNS06_RS18425	COG1028	Short-chain dehydrogenase reductase Sdr
FNS06_RS18435	COG0747	negative chemotaxis
FNS06_RS18440	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FNS06_RS18445	COG2301	Belongs to the HpcH HpaI aldolase family
FNS06_RS18465	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FNS06_RS18470	COG1802	Transcriptional regulator
FNS06_RS18475	COG0747	negative chemotaxis
FNS06_RS18480	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FNS06_RS18490	COG4172	Belongs to the ABC transporter superfamily
FNS06_RS18495	COG1028	Short-chain dehydrogenase reductase Sdr
FNS06_RS18500	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FNS06_RS18505	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FNS06_RS18510	COG3842	ATPase activity
FNS06_RS18515	COG1653	transport
FNS06_RS18525	COG0395	ABC-type sugar transport system, permease component
FNS06_RS18530	COG1136	(ABC) transporter
FNS06_RS18530	COG0577	efflux transmembrane transporter activity
FNS06_RS18535	COG0577	efflux transmembrane transporter activity
FNS06_RS18535	COG1136	(ABC) transporter
FNS06_RS18570	COG2205	protein histidine kinase activity
FNS06_RS18575	COG0745	RESPONSE REGULATOR receiver
FNS06_RS18580	COG3920	Histidine kinase
FNS06_RS18595	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
FNS06_RS18600	COG1132	(ABC) transporter
FNS06_RS18605	COG1959	2 iron, 2 sulfur cluster binding
FNS06_RS18625	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
FNS06_RS18635	COG2989	Protein conserved in bacteria
FNS06_RS18640	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FNS06_RS18650	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
FNS06_RS18655	COG2943	transferase activity, transferring hexosyl groups
FNS06_RS18660	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
FNS06_RS18680	COG3093	addiction module antidote protein HigA
FNS06_RS18695	COG2205	protein histidine kinase activity
FNS06_RS18705	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
FNS06_RS18710	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
FNS06_RS18715	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
FNS06_RS18720	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FNS06_RS18725	COG1840	ABC-type Fe3 transport system, periplasmic component
FNS06_RS18730	COG3842	ATPase activity
FNS06_RS18735	COG4149	molybdate abc transporter
FNS06_RS18760	COG2189	Belongs to the N(4) N(6)-methyltransferase family
FNS06_RS18775	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
FNS06_RS18780	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FNS06_RS18800	COG1404	Belongs to the peptidase S8 family
FNS06_RS18805	COG0629	single-stranded DNA binding
FNS06_RS18825	COG1595	DNA-templated transcription, initiation
FNS06_RS18845	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
FNS06_RS18850	COG1253	flavin adenine dinucleotide binding
FNS06_RS18880	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FNS06_RS18885	COG1862	Preprotein translocase
FNS06_RS18900	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FNS06_RS18910	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FNS06_RS18915	COG0805	protein transport
FNS06_RS18930	COG3842	ATPase activity
FNS06_RS18935	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
FNS06_RS18940	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
FNS06_RS18945	COG1994	Peptidase M50
FNS06_RS18950	COG1472	Belongs to the glycosyl hydrolase 3 family
FNS06_RS18965	COG0232	Belongs to the dGTPase family. Type 2 subfamily
FNS06_RS18970	COG0316	Belongs to the HesB IscA family
FNS06_RS18985	COG0525	valine-tRNA ligase activity
FNS06_RS18995	COG1538	Outer membrane efflux protein
FNS06_RS19000	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FNS06_RS19010	COG2133	pyrroloquinoline quinone binding
FNS06_RS19030	COG0270	DNA (cytosine-5-)-methyltransferase activity
FNS06_RS19035	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
FNS06_RS19090	COG1132	(ABC) transporter
FNS06_RS19100	COG0154	amidase activity
FNS06_RS19110	COG4166	transmembrane transport
FNS06_RS19115	COG0601	transmembrane transport
FNS06_RS19120	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FNS06_RS19130	COG0154	amidase activity
FNS06_RS19135	COG0252	asparaginase activity
FNS06_RS19160	COG0444	Belongs to the ABC transporter superfamily
FNS06_RS19165	COG4608	Belongs to the ABC transporter superfamily
FNS06_RS19175	COG2188	Transcriptional regulator
FNS06_RS19180	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
FNS06_RS19185	COG1028	Short-chain dehydrogenase reductase Sdr
FNS06_RS19190	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
FNS06_RS19195	COG1414	Transcriptional regulator
FNS06_RS19210	COG1028	Short-chain dehydrogenase reductase Sdr
FNS06_RS19215	COG2072	flavoprotein involved in K transport
FNS06_RS19235	COG1063	alcohol dehydrogenase
FNS06_RS19245	COG0657	acetylesterase activity
FNS06_RS19255	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FNS06_RS19260	COG2897	thiosulfate sulfurtransferase activity
FNS06_RS19270	COG0737	Belongs to the 5'-nucleotidase family
FNS06_RS19280	COG1126	abc transporter atp-binding protein
FNS06_RS19285	COG0765	amino acid transport
FNS06_RS19290	COG4597	amino acid ABC transporter
FNS06_RS19295	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FNS06_RS19300	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
FNS06_RS19315	COG1215	transferase activity, transferring glycosyl groups
FNS06_RS19335	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FNS06_RS19340	COG2204	response regulator
FNS06_RS19345	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FNS06_RS19370	COG3842	ATPase activity
FNS06_RS19385	COG1653	transport
FNS06_RS19390	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
FNS06_RS19400	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
FNS06_RS19410	COG0318	PFAM AMP-dependent synthetase and ligase
FNS06_RS19415	COG0366	Alpha amylase catalytic
FNS06_RS19420	COG0488	(ABC) transporter
FNS06_RS19445	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FNS06_RS19460	COG0655	NAD(P)H dehydrogenase (quinone) activity
FNS06_RS19465	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FNS06_RS19465	COG0475	glutathione-regulated potassium exporter activity
FNS06_RS19485	COG0366	Alpha amylase catalytic
FNS06_RS19490	COG0366	Alpha amylase catalytic
FNS06_RS19520	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FNS06_RS19525	COG2759	Belongs to the formate--tetrahydrofolate ligase family
FNS06_RS19555	COG0411	ABC transporter
FNS06_RS19590	COG1960	acyl-CoA dehydrogenase activity
FNS06_RS19595	COG1960	acyl-CoA dehydrogenase activity
FNS06_RS19615	COG2239	Acts as a magnesium transporter
FNS06_RS19620	COG0281	malic enzyme
FNS06_RS19620	COG0280	phosphate acetyltransferase
FNS06_RS19635	COG1254	Belongs to the acylphosphatase family
FNS06_RS19640	COG4770	biotin carboxylase activity
FNS06_RS19645	COG0861	Integral membrane protein TerC family
FNS06_RS19650	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FNS06_RS19660	COG0546	phosphoglycolate phosphatase activity
FNS06_RS19665	COG1028	Short-chain dehydrogenase reductase Sdr
FNS06_RS19690	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FNS06_RS19695	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FNS06_RS19700	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FNS06_RS19705	COG0203	ribosomal protein L17
FNS06_RS19715	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
FNS06_RS19720	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FNS06_RS19725	COG0563	adenylate kinase activity
FNS06_RS19740	COG1841	ribosomal large subunit assembly
FNS06_RS19745	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
FNS06_RS19750	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
FNS06_RS19755	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FNS06_RS19760	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
FNS06_RS19765	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FNS06_RS19785	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
FNS06_RS19790	COG0255	Belongs to the universal ribosomal protein uL29 family
FNS06_RS19795	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
FNS06_RS19800	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
FNS06_RS19805	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
FNS06_RS19810	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
FNS06_RS19830	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
FNS06_RS19835	COG0051	transcription antitermination factor activity, RNA binding
FNS06_RS19850	COG0049	tRNA binding
FNS06_RS19860	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FNS06_RS19865	COG0085	RNA polymerase activity
FNS06_RS19870	COG0222	ribosome binding
FNS06_RS19880	COG0081	regulation of translation
FNS06_RS19885	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
FNS06_RS19920	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FNS06_RS19930	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FNS06_RS19945	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FNS06_RS20000	COG0438	transferase activity, transferring glycosyl groups
FNS06_RS20050	COG0243	molybdopterin cofactor binding
FNS06_RS20065	COG0673	inositol 2-dehydrogenase activity
FNS06_RS20080	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FNS06_RS20085	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FNS06_RS20090	COG1566	PFAM secretion protein HlyD family protein
FNS06_RS20095	COG3713	MltA-interacting MipA family protein
FNS06_RS20105	COG2205	protein histidine kinase activity
FNS06_RS20110	COG2853	Lipoprotein
FNS06_RS20120	COG0625	glutathione transferase activity
FNS06_RS20135	COG1309	transcriptional regulator
FNS06_RS20165	COG2045	Belongs to the ComB family
FNS06_RS20315	COG0438	transferase activity, transferring glycosyl groups
FNS06_RS20330	COG1218	3'(2'),5'-bisphosphate nucleotidase
FNS06_RS20335	COG1192	Involved in chromosome partitioning
FNS06_RS20340	COG1120	ATPase activity
FNS06_RS20345	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FNS06_RS20395	COG4948	Mandelate Racemase Muconate Lactonizing
FNS06_RS20410	COG0405	Gamma-glutamyltransferase
FNS06_RS20425	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FNS06_RS20430	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FNS06_RS20440	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FNS06_RS20455	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FNS06_RS20460	COG3609	addiction module antidote protein, CC2985 family
FNS06_RS20470	COG4679	PFAM Phage derived protein Gp49-like (DUF891)
FNS06_RS20490	COG3047	cAMP biosynthetic process
FNS06_RS20495	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
FNS06_RS20500	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FNS06_RS20505	COG0747	negative chemotaxis
FNS06_RS20515	COG1522	sequence-specific DNA binding
FNS06_RS20520	COG2515	1-aminocyclopropane-1-carboxylate deaminase
FNS06_RS20575	COG0163	prenyltransferase activity
FNS06_RS20610	COG0318	PFAM AMP-dependent synthetase and ligase
FNS06_RS20740	COG4397	Mu-like prophage major head subunit gpT
FNS06_RS20880	COG0629	single-stranded DNA binding
FNS06_RS20915	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FNS06_RS20945	COG1720	tRNA m6t6A37 methyltransferase activity
FNS06_RS20955	COG1956	GAF domain-containing protein
FNS06_RS20990	COG0318	PFAM AMP-dependent synthetase and ligase
FNS06_RS20995	COG2827	Endonuclease containing a URI domain
FNS06_RS21005	COG1309	transcriptional regulator
FNS06_RS21010	COG1234	tRNA 3'-trailer cleavage
FNS06_RS21015	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FNS06_RS21040	COG1595	DNA-templated transcription, initiation
FNS06_RS21050	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FNS06_RS21060	COG0673	inositol 2-dehydrogenase activity
FNS06_RS21075	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
FNS06_RS21100	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FNS06_RS21120	COG0400	carboxylic ester hydrolase activity
FNS06_RS21125	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FNS06_RS21135	COG0646	methionine synthase
FNS06_RS21135	COG1410	methionine synthase
FNS06_RS21150	COG2853	Lipoprotein
FNS06_RS21160	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FNS06_RS21180	COG3023	N-Acetylmuramoyl-L-alanine amidase
FNS06_RS21210	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FNS06_RS21235	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FNS06_RS21240	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FNS06_RS21245	COG0812	UDP-N-acetylmuramate dehydrogenase activity
FNS06_RS21250	COG1181	Belongs to the D-alanine--D-alanine ligase family
FNS06_RS21255	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
FNS06_RS21260	COG0849	cell division
FNS06_RS21265	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FNS06_RS21275	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FNS06_RS21290	COG0497	DNA recombination
FNS06_RS21295	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FNS06_RS21300	COG0500	methyltransferase
FNS06_RS21305	COG0006	proline dipeptidase activity
FNS06_RS21305	COG0006	proline dipeptidase activity
FNS06_RS21320	COG2264	protein methyltransferase activity
FNS06_RS21325	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
FNS06_RS21330	COG0210	DNA helicase
FNS06_RS21350	COG0521	Mo-molybdopterin cofactor biosynthetic process
FNS06_RS21360	COG1573	uracil-dna glycosylase
FNS06_RS21380	COG0450	alkyl hydroperoxide reductase
FNS06_RS21385	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FNS06_RS21405	COG1136	(ABC) transporter
FNS06_RS21410	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FNS06_RS21420	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
FNS06_RS21420	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FNS06_RS21430	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
FNS06_RS21495	COG4774	siderophore transport
FNS06_RS21500	COG0747	negative chemotaxis
FNS06_RS21515	COG2308	Evidence 4 Homologs of previously reported genes of
FNS06_RS21530	COG0483	inositol monophosphate 1-phosphatase activity
FNS06_RS21550	COG0405	Gamma-glutamyltransferase
FNS06_RS21560	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FNS06_RS21570	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FNS06_RS21580	COG0398	Pfam SNARE associated Golgi protein
FNS06_RS21590	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FNS06_RS21610	COG2336	PFAM SpoVT AbrB
FNS06_RS21615	COG4953	penicillin-binding protein 1C
FNS06_RS21625	COG2989	Protein conserved in bacteria
FNS06_RS21630	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FNS06_RS21640	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
FNS06_RS21680	COG1429	ligase activity, forming nitrogen-metal bonds
FNS06_RS21685	COG4771	TonB-dependent receptor
FNS06_RS21700	COG1268	BioY protein
FNS06_RS21710	COG0583	DNA-binding transcription factor activity
FNS06_RS21720	COG1522	sequence-specific DNA binding
FNS06_RS21730	COG1309	transcriptional regulator
FNS06_RS21740	COG2814	Major facilitator Superfamily
FNS06_RS21745	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FNS06_RS21760	COG1733	regulation of RNA biosynthetic process
FNS06_RS21815	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
FNS06_RS21830	COG2835	tetraacyldisaccharide 4'-kinase activity
FNS06_RS21855	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FNS06_RS21875	COG1176	ABC-type spermidine putrescine transport system, permease component I
FNS06_RS21880	COG4208	sulfate ABC transporter
FNS06_RS21885	COG0318	PFAM AMP-dependent synthetase and ligase
FNS06_RS21900	COG2813	Specifically methylates the guanine in position
FNS06_RS21920	COG0697	spore germination
FNS06_RS21925	COG1051	belongs to the nudix hydrolase family
FNS06_RS21930	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FNS06_RS21940	COG2032	superoxide dismutase activity
FNS06_RS21950	COG2814	Major facilitator Superfamily
FNS06_RS21955	COG1566	PFAM secretion protein HlyD family protein
FNS06_RS21970	COG0183	Belongs to the thiolase family
FNS06_RS21985	COG3842	ATPase activity
FNS06_RS21990	COG0583	DNA-binding transcription factor activity
FNS06_RS22015	COG2814	Major facilitator Superfamily
FNS06_RS22020	COG0708	Exodeoxyribonuclease III
FNS06_RS22025	COG0459	protein refolding
FNS06_RS22030	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
FNS06_RS22035	COG2814	Major facilitator Superfamily
FNS06_RS22050	COG1028	Short-chain dehydrogenase reductase Sdr
FNS06_RS22055	COG2814	Major facilitator Superfamily
FNS06_RS22080	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FNS06_RS22085	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FNS06_RS22120	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FNS06_RS22125	COG1028	Short-chain dehydrogenase reductase Sdr
FNS06_RS22130	COG2130	NADP-dependent
FNS06_RS22150	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
FNS06_RS22185	COG1960	acyl-CoA dehydrogenase activity
FNS06_RS22200	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FNS06_RS22205	COG1028	Short-chain dehydrogenase reductase Sdr
FNS06_RS22210	COG1802	Transcriptional regulator
FNS06_RS22215	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FNS06_RS22225	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FNS06_RS22230	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FNS06_RS22235	COG1024	Enoyl-CoA hydratase
FNS06_RS22300	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FNS06_RS22325	COG0697	spore germination
FNS06_RS22330	COG3179	chitinase
FNS06_RS22335	COG4172	Belongs to the ABC transporter superfamily
FNS06_RS22345	COG0601	transmembrane transport
FNS06_RS22365	COG3386	PFAM SMP-30 Gluconolaconase
FNS06_RS22380	COG3609	addiction module antidote protein, CC2985 family
FNS06_RS22400	COG1053	succinate dehydrogenase
FNS06_RS22415	COG1028	Short-chain dehydrogenase reductase Sdr
FNS06_RS22440	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
FNS06_RS22445	COG4149	molybdate abc transporter
FNS06_RS22460	COG0784	Response regulator, receiver
FNS06_RS22460	COG5002	protein histidine kinase activity
FNS06_RS22465	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FNS06_RS22470	COG4175	Glycine betaine
FNS06_RS22475	COG4176	ABC-type proline glycine betaine transport system permease component
FNS06_RS22485	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FNS06_RS22485	COG1181	Belongs to the D-alanine--D-alanine ligase family
FNS06_RS22490	COG1840	ABC-type Fe3 transport system, periplasmic component
FNS06_RS22495	COG1840	ABC-type Fe3 transport system, periplasmic component
FNS06_RS22505	COG3842	ATPase activity
FNS06_RS22520	COG0210	DNA helicase
FNS06_RS22525	COG3608	succinylglutamate desuccinylase aspartoacylase
FNS06_RS22530	COG4608	Belongs to the ABC transporter superfamily
FNS06_RS22535	COG0444	Belongs to the ABC transporter superfamily
FNS06_RS22550	COG0747	negative chemotaxis
FNS06_RS22560	COG0505	Belongs to the CarA family
FNS06_RS22565	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FNS06_RS22570	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FNS06_RS22575	COG0828	Belongs to the bacterial ribosomal protein bS21 family
FNS06_RS22585	COG4149	molybdate abc transporter
FNS06_RS22590	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FNS06_RS22605	COG1024	Enoyl-CoA hydratase
FNS06_RS22615	COG0433	COG0433 Predicted ATPase
FNS06_RS22625	COG1376	ErfK ybiS ycfS ynhG family protein
FNS06_RS22630	COG3108	Peptidase M15
FNS06_RS22635	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FNS06_RS22655	COG1872	DUF167
FNS06_RS22660	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FNS06_RS22665	COG4608	Belongs to the ABC transporter superfamily
FNS06_RS22670	COG0444	Belongs to the ABC transporter superfamily
FNS06_RS22675	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FNS06_RS22680	COG0601	transmembrane transport
FNS06_RS22715	COG0227	Belongs to the bacterial ribosomal protein bL28 family
FNS06_RS22725	COG1703	isobutyryl-CoA mutase activity
FNS06_RS22730	COG5265	(ABC) transporter
FNS06_RS22750	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FNS06_RS22750	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FNS06_RS22760	COG2337	Toxic component of a toxin-antitoxin (TA) module
FNS06_RS22765	COG4166	transmembrane transport
FNS06_RS22775	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
FNS06_RS22780	COG0167	dihydroorotate dehydrogenase activity
FNS06_RS22810	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FNS06_RS22810	COG1199	ATP-dependent helicase activity
FNS06_RS22860	COG1522	sequence-specific DNA binding
FNS06_RS22865	COG3660	Nucleoside-diphosphate-sugar epimerase
FNS06_RS22875	COG0492	ferredoxin-NADP+ reductase activity
FNS06_RS22880	COG0583	DNA-binding transcription factor activity
FNS06_RS22890	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FNS06_RS22900	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
FNS06_RS22910	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FNS06_RS22935	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FNS06_RS22940	COG0450	alkyl hydroperoxide reductase
FNS06_RS22960	COG0556	nucleotide-excision repair
FNS06_RS22965	COG1028	Short-chain dehydrogenase reductase Sdr
FNS06_RS22975	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FNS06_RS22980	COG1763	Mo-molybdopterin cofactor biosynthetic process
FNS06_RS22990	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
FNS06_RS22995	COG0314	molybdopterin synthase activity
FNS06_RS23010	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FNS06_RS23015	COG1268	BioY protein
FNS06_RS23025	COG1846	Transcriptional regulator
FNS06_RS23030	COG0745	RESPONSE REGULATOR receiver
FNS06_RS23035	COG2205	protein histidine kinase activity
FNS06_RS23040	COG1522	sequence-specific DNA binding
FNS06_RS23065	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FNS06_RS23075	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FNS06_RS23080	COG1024	Enoyl-CoA hydratase
FNS06_RS23085	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FNS06_RS23100	COG1024	Enoyl-CoA hydratase
FNS06_RS23115	COG0640	Transcriptional regulator
FNS06_RS23145	COG0523	cobalamin synthesis protein
FNS06_RS23150	COG0583	DNA-binding transcription factor activity
FNS06_RS23175	COG3384	dioxygenase
FNS06_RS23180	COG3384	dioxygenase
FNS06_RS23185	COG0583	DNA-binding transcription factor activity
FNS06_RS23195	COG2084	Dehydrogenase
FNS06_RS23200	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FNS06_RS23205	COG1902	pentaerythritol trinitrate reductase activity
FNS06_RS23210	COG1902	pentaerythritol trinitrate reductase activity
FNS06_RS23220	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
FNS06_RS23225	COG0850	regulation of cytokinetic process
FNS06_RS23230	COG2894	cell division
FNS06_RS23235	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
FNS06_RS23255	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
FNS06_RS23320	COG0701	Predicted permease
FNS06_RS23350	COG1271	oxidase subunit
FNS06_RS23355	COG1294	oxidase, subunit
FNS06_RS23360	COG0784	Response regulator, receiver
FNS06_RS23360	COG4191	Histidine kinase
FNS06_RS23400	COG1755	Isoprenylcysteine carboxyl methyltransferase
FNS06_RS23405	COG3424	synthase
FNS06_RS23410	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
FNS06_RS23435	COG2010	Cytochrome c
FNS06_RS23435	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FNS06_RS23440	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FNS06_RS23450	COG1126	abc transporter atp-binding protein
FNS06_RS23455	COG0765	amino acid transport
FNS06_RS23465	COG3618	amidohydrolase
FNS06_RS23475	COG2084	Dehydrogenase
FNS06_RS23480	COG2084	Dehydrogenase
FNS06_RS23495	COG0670	Belongs to the BI1 family
FNS06_RS23520	COG0667	Aldo Keto reductase
FNS06_RS23530	COG0798	PFAM Bile acid sodium symporter
FNS06_RS23550	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FNS06_RS23570	COG1595	DNA-templated transcription, initiation
FNS06_RS23580	COG4774	siderophore transport
FNS06_RS23585	COG0210	DNA helicase
FNS06_RS23590	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FNS06_RS23605	COG2354	Protein conserved in bacteria
FNS06_RS23615	COG2084	Dehydrogenase
FNS06_RS23620	COG0156	8-amino-7-oxononanoate synthase activity
FNS06_RS23625	COG2211	Major facilitator Superfamily
FNS06_RS23630	COG5398	heme oxygenase
FNS06_RS23635	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FNS06_RS23640	COG1028	Short-chain dehydrogenase reductase Sdr
FNS06_RS23650	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FNS06_RS23660	COG0242	peptide deformylase activity
FNS06_RS23665	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FNS06_RS23685	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FNS06_RS23690	COG2171	N-acyltransferase activity
FNS06_RS23715	COG1176	ABC-type spermidine putrescine transport system, permease component I
FNS06_RS23720	COG4149	molybdate abc transporter
FNS06_RS23725	COG3842	ATPase activity
FNS06_RS23750	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FNS06_RS23755	COG0218	Necessary for normal cell division and for the maintenance of normal septation
FNS06_RS23760	COG0706	membrane insertase activity
FNS06_RS23775	COG0230	Belongs to the bacterial ribosomal protein bL34 family
FNS06_RS23800	COG1176	ABC-type spermidine putrescine transport system, permease component I
FNS06_RS23810	COG3842	ATPase activity
FNS06_RS23815	COG1177	transmembrane transport
FNS06_RS23820	COG2814	Major facilitator Superfamily
FNS06_RS23825	COG2814	Major facilitator Superfamily
FNS06_RS23835	COG1653	transport
FNS06_RS23840	COG1175	transmembrane transport
FNS06_RS23845	COG0395	ABC-type sugar transport system, permease component
FNS06_RS23860	COG1063	alcohol dehydrogenase
FNS06_RS23870	COG2824	Alkylphosphonate utilization operon protein PhnA
FNS06_RS23885	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
FNS06_RS23900	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
FNS06_RS23910	COG1496	oxidoreductase activity
FNS06_RS23920	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FNS06_RS23925	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
FNS06_RS23935	COG0012	GTP binding
FNS06_RS23955	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
FNS06_RS23965	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FNS06_RS23980	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FNS06_RS23990	COG4974	Belongs to the 'phage' integrase family
FNS06_RS23995	COG1280	lysine exporter protein (LysE YggA)
FNS06_RS24010	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FNS06_RS24015	COG0508	dehydrogenase complex catalyzes the overall conversion of
FNS06_RS24030	COG0045	succinate-CoA ligase (ADP-forming) activity
FNS06_RS24035	COG0039	L-malate dehydrogenase activity
FNS06_RS24040	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
FNS06_RS24050	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FNS06_RS24085	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FNS06_RS24120	COG1028	Short-chain dehydrogenase reductase Sdr
FNS06_RS24135	COG0583	DNA-binding transcription factor activity
FNS06_RS24140	COG2271	Major facilitator Superfamily
FNS06_RS24175	COG0747	negative chemotaxis
FNS06_RS24185	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FNS06_RS24195	COG4608	Belongs to the ABC transporter superfamily
FNS06_RS24215	COG0154	amidase activity
FNS06_RS24225	COG2205	protein histidine kinase activity
FNS06_RS24235	COG2205	protein histidine kinase activity
FNS06_RS24240	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
FNS06_RS24255	COG0126	phosphoglycerate kinase activity
FNS06_RS24265	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FNS06_RS24280	COG0318	PFAM AMP-dependent synthetase and ligase
FNS06_RS24315	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
FNS06_RS24320	COG3409	Peptidoglycan-binding domain 1 protein
FNS06_RS24320	COG0860	N-Acetylmuramoyl-L-alanine amidase
FNS06_RS24325	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
FNS06_RS24330	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FNS06_RS24350	COG1696	Membrane protein involved in D-alanine export
FNS06_RS24360	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
FNS06_RS24375	COG1704	LemA family
FNS06_RS24380	COG0501	Belongs to the peptidase M48B family
FNS06_RS24425	COG0747	negative chemotaxis
FNS06_RS24430	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
FNS06_RS24480	COG0464	growth
FNS06_RS24495	COG0640	Transcriptional regulator
FNS06_RS24515	COG4221	oxidoreductase activity
FNS06_RS24560	COG2059	Chromate
FNS06_RS24570	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
FNS06_RS24575	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
FNS06_RS24580	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FNS06_RS24600	COG3485	protocatechuate 3,4-dioxygenase
FNS06_RS24605	COG3485	protocatechuate 3,4-dioxygenase
FNS06_RS24620	COG0860	N-Acetylmuramoyl-L-alanine amidase
FNS06_RS24640	COG1028	Short-chain dehydrogenase reductase Sdr
FNS06_RS24650	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FNS06_RS24655	COG1028	Short-chain dehydrogenase reductase Sdr
FNS06_RS24735	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FNS06_RS24755	COG0601	transmembrane transport
FNS06_RS24760	COG4608	Belongs to the ABC transporter superfamily
FNS06_RS24790	COG3181	Tripartite tricarboxylate transporter family receptor
FNS06_RS24805	COG4172	Belongs to the ABC transporter superfamily
FNS06_RS24810	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FNS06_RS24830	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
FNS06_RS24870	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FNS06_RS24880	COG0446	pyridine nucleotide-disulphide oxidoreductase
FNS06_RS24880	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FNS06_RS24905	COG0674	pyruvate-flavodoxin oxidoreductase activity
FNS06_RS24905	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
FNS06_RS24925	COG0500	methyltransferase
FNS06_RS24935	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FNS06_RS24940	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
FNS06_RS24945	COG1902	pentaerythritol trinitrate reductase activity
FNS06_RS24985	COG0559	Belongs to the binding-protein-dependent transport system permease family
FNS06_RS25075	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
FNS06_RS25080	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FNS06_RS25085	COG0189	ligase activity
FNS06_RS25085	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FNS06_RS25090	COG0072	phenylalanine-tRNA ligase activity
FNS06_RS25095	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
FNS06_RS25100	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
FNS06_RS25105	COG0291	Belongs to the bacterial ribosomal protein bL35 family
FNS06_RS25110	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
FNS06_RS25120	COG0297	glycogen (starch) synthase activity
FNS06_RS25150	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FNS06_RS25210	COG1137	ATPase activity
FNS06_RS25215	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
FNS06_RS25220	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FNS06_RS25230	COG0071	Belongs to the small heat shock protein (HSP20) family
FNS06_RS25250	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
FNS06_RS25255	COG0539	negative regulation of cytoplasmic translation
FNS06_RS25260	COG0616	signal peptide processing
FNS06_RS25265	COG0776	regulation of translation
FNS06_RS25275	COG2423	ornithine cyclodeaminase activity
FNS06_RS25280	COG0135	phosphoribosylanthranilate isomerase activity
FNS06_RS25295	COG3178	'Phosphotransferase
FNS06_RS25300	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FNS06_RS25310	COG1074	ATP-dependent DNA helicase activity
FNS06_RS25320	COG0285	dihydrofolate synthase activity
FNS06_RS25325	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
FNS06_RS25335	COG0133	tryptophan synthase activity
FNS06_RS25365	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FNS06_RS25380	COG0625	glutathione transferase activity
FNS06_RS25405	COG0174	glutamine synthetase
FNS06_RS25410	COG1024	Enoyl-CoA hydratase
FNS06_RS25415	COG0318	PFAM AMP-dependent synthetase and ligase
FNS06_RS25420	COG1177	transmembrane transport
FNS06_RS25435	COG3842	ATPase activity
FNS06_RS25445	COG1178	ABC-type Fe3 transport system permease component
FNS06_RS25450	COG3842	ATPase activity
FNS06_RS25455	COG1840	ABC-type Fe3 transport system, periplasmic component
FNS06_RS25485	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
FNS06_RS25500	COG1028	Short-chain dehydrogenase reductase Sdr
FNS06_RS25505	COG2267	carboxylic ester hydrolase activity
FNS06_RS25520	COG4174	ABC transporter (Permease)
FNS06_RS25525	COG4239	(ABC) transporter, permease
FNS06_RS25530	COG4172	Belongs to the ABC transporter superfamily
FNS06_RS25535	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FNS06_RS25540	COG1999	signal sequence binding
FNS06_RS25545	COG1040	competence protein
FNS06_RS25550	COG2226	methyltransferase
FNS06_RS25560	COG0488	(ABC) transporter
FNS06_RS25565	COG0494	nUDIX hydrolase
FNS06_RS25570	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
FNS06_RS25575	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FNS06_RS25580	COG0653	protein targeting
FNS06_RS25585	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
FNS06_RS25600	COG4974	Belongs to the 'phage' integrase family
FNS06_RS25615	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
FNS06_RS25620	COG4536	flavin adenine dinucleotide binding
FNS06_RS25630	COG1283	sodium-dependent phosphate transmembrane transporter activity
FNS06_RS25665	COG0412	Dienelactone hydrolase
FNS06_RS25680	COG0137	argininosuccinate synthase activity
FNS06_RS25690	COG0820	rRNA (adenine-C2-)-methyltransferase activity
FNS06_RS25705	COG1595	DNA-templated transcription, initiation
FNS06_RS25710	COG3806	Anti-sigma factor
FNS06_RS25720	COG1663	tetraacyldisaccharide 4'-kinase activity
FNS06_RS25725	COG1519	Transferase
FNS06_RS25735	COG0438	transferase activity, transferring glycosyl groups
FNS06_RS25745	COG1597	lipid kinase activity
FNS06_RS25745	COG1803	Methylglyoxal synthase
FNS06_RS25755	COG0312	modulator of DNA gyrase
FNS06_RS25760	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FNS06_RS25770	COG4589	Belongs to the CDS family
FNS06_RS25775	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
FNS06_RS25785	COG2264	protein methyltransferase activity
FNS06_RS25790	COG1702	phosphate starvation-inducible protein PhoH
FNS06_RS25800	COG4232	protein-disulfide reductase activity
FNS06_RS25805	COG1678	Uncharacterized ACR, COG1678
FNS06_RS25815	COG0612	Peptidase, M16
FNS06_RS25830	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
FNS06_RS25835	COG3346	SURF1 family
FNS06_RS25855	COG0109	protoheme IX farnesyltransferase activity
FNS06_RS25860	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FNS06_RS25865	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FNS06_RS25870	COG0312	modulator of DNA gyrase
FNS06_RS25900	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
FNS06_RS25910	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FNS06_RS25915	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FNS06_RS25920	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FNS06_RS25935	COG1196	nuclear chromosome segregation
FNS06_RS25950	COG1194	a g-specific adenine glycosylase
FNS06_RS25955	COG0494	nUDIX hydrolase
FNS06_RS25970	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FNS06_RS25975	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
FNS06_RS25995	COG1802	Transcriptional regulator
FNS06_RS26000	COG0747	negative chemotaxis
FNS06_RS26020	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FNS06_RS26025	COG0601	transmembrane transport
FNS06_RS26030	COG0747	negative chemotaxis
FNS06_RS26055	COG4608	Belongs to the ABC transporter superfamily
FNS06_RS26065	COG2816	NAD+ diphosphatase activity
FNS06_RS26085	COG3474	cytochrome
FNS06_RS26095	COG4166	transmembrane transport
FNS06_RS26110	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FNS06_RS26115	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
FNS06_RS26125	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
FNS06_RS26130	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
FNS06_RS26155	COG0181	hydroxymethylbilane synthase activity
FNS06_RS26160	COG0625	glutathione transferase activity
FNS06_RS26170	COG3766	membrane
FNS06_RS26175	COG0754	glutathionylspermidine amidase activity
FNS06_RS26250	COG3963	phosphatidate phosphatase activity
FNS06_RS26255	COG2902	Dehydrogenase
FNS06_RS26285	COG0154	amidase activity
FNS06_RS26300	COG0583	DNA-binding transcription factor activity
FNS06_RS26305	COG2030	dehydratase
FNS06_RS26310	COG0196	riboflavin kinase activity
FNS06_RS26315	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FNS06_RS26320	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
FNS06_RS26330	COG0612	Peptidase, M16
FNS06_RS26335	COG0612	Peptidase, M16
FNS06_RS26340	COG0166	Belongs to the GPI family
FNS06_RS26345	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
FNS06_RS26355	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FNS06_RS26360	COG1396	sequence-specific DNA binding
FNS06_RS26365	COG0815	Transfers the fatty acyl group on membrane lipoproteins
FNS06_RS26370	COG1253	flavin adenine dinucleotide binding
FNS06_RS26380	COG1702	phosphate starvation-inducible protein PhoH
FNS06_RS26385	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FNS06_RS26415	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
FNS06_RS26420	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
FNS06_RS26435	COG0730	response to heat
FNS06_RS26440	COG0180	Tryptophanyl-tRNA synthetase
FNS06_RS26445	COG0728	peptidoglycan biosynthetic process
FNS06_RS26465	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
FNS06_RS26475	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
FNS06_RS26485	COG0131	Imidazoleglycerol-phosphate dehydratase
FNS06_RS26495	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
FNS06_RS26505	COG1396	sequence-specific DNA binding
FNS06_RS26520	COG1139	Iron-sulfur cluster binding protein
FNS06_RS26525	COG0247	lactate metabolic process
FNS06_RS26530	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
FNS06_RS26540	COG3030	protein affecting phage T7 exclusion by the F plasmid
FNS06_RS26545	COG0406	alpha-ribazole phosphatase activity
FNS06_RS26550	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
FNS06_RS26555	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FNS06_RS26570	COG0424	maF-like protein
FNS06_RS26580	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
FNS06_RS26590	COG1981	membrane
FNS06_RS26600	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
FNS06_RS26605	COG0730	response to heat
FNS06_RS26625	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FNS06_RS26630	COG1331	Highly conserved protein containing a thioredoxin domain
FNS06_RS26635	COG3411	Ferredoxin
FNS06_RS26645	COG0445	tRNA wobble uridine modification
FNS06_RS26675	COG0495	leucyl-tRNA aminoacylation
FNS06_RS26700	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FNS06_RS26720	COG0745	RESPONSE REGULATOR receiver
FNS06_RS26730	COG1234	tRNA 3'-trailer cleavage
FNS06_RS26755	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FNS06_RS26760	COG0601	transmembrane transport
FNS06_RS26765	COG0747	negative chemotaxis
FNS06_RS26770	COG4166	transmembrane transport
FNS06_RS26775	COG0284	orotidine-5'-phosphate decarboxylase activity
FNS06_RS26780	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FNS06_RS26780	COG0543	2 iron, 2 sulfur cluster binding
FNS06_RS26785	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
FNS06_RS26800	COG1607	acyl-coa hydrolase
FNS06_RS26805	COG0318	PFAM AMP-dependent synthetase and ligase
FNS06_RS26825	COG1802	Transcriptional regulator
FNS06_RS26830	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FNS06_RS26835	COG1024	Enoyl-CoA hydratase
FNS06_RS26850	COG3842	ATPase activity
FNS06_RS26865	COG1283	sodium-dependent phosphate transmembrane transporter activity
FNS06_RS26875	COG0436	Aminotransferase
FNS06_RS26880	COG4166	transmembrane transport
FNS06_RS26905	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
FNS06_RS26910	COG2218	PFAM glutamate synthase alpha subunit domain protein
FNS06_RS26915	COG0069	glutamate synthase activity
FNS06_RS26920	COG0174	glutamine synthetase
FNS06_RS26930	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
FNS06_RS26935	COG3842	ATPase activity
FNS06_RS26940	COG1176	ABC-type spermidine putrescine transport system, permease component I
FNS06_RS26955	COG0004	ammonium transporteR
FNS06_RS26960	COG0590	tRNA wobble adenosine to inosine editing
FNS06_RS26970	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
FNS06_RS26985	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
FNS06_RS26990	COG1187	pseudouridine synthase activity
FNS06_RS26995	COG0742	ribosomal rna small subunit methyltransferase
FNS06_RS27005	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FNS06_RS27010	COG1420	regulation of RNA biosynthetic process
FNS06_RS27020	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
FNS06_RS27025	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
FNS06_RS27030	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FNS06_RS27035	COG1011	Hydrolase
FNS06_RS27045	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
FNS06_RS27050	COG0792	nuclease activity
FNS06_RS27080	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FNS06_RS27105	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FNS06_RS27110	COG0583	DNA-binding transcription factor activity
FNS06_RS27120	COG0235	Class ii aldolase
FNS06_RS27135	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
FNS06_RS27150	COG5002	protein histidine kinase activity
FNS06_RS27160	COG0573	inorganic phosphate transmembrane transporter activity
FNS06_RS27165	COG0573	inorganic phosphate transmembrane transporter activity
FNS06_RS27170	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FNS06_RS27180	COG0745	RESPONSE REGULATOR receiver
FNS06_RS27195	COG0500	methyltransferase
FNS06_RS27205	COG0347	Belongs to the P(II) protein family
FNS06_RS27210	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FNS06_RS27215	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
FNS06_RS27220	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FNS06_RS27225	COG0552	protein localization to endoplasmic reticulum
FNS06_RS27230	COG2917	probably involved in intracellular septation
FNS06_RS27240	COG0328	RNA-DNA hybrid ribonuclease activity
FNS06_RS27245	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FNS06_RS27260	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FNS06_RS27265	COG0509	glycine decarboxylation via glycine cleavage system
FNS06_RS27270	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FNS06_RS27275	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FNS06_RS27290	COG3263	regulation of cellular component size
FNS06_RS27295	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FNS06_RS27320	COG2030	dehydratase
FNS06_RS27325	COG1028	Short-chain dehydrogenase reductase Sdr
FNS06_RS27330	COG0183	Belongs to the thiolase family
FNS06_RS27340	COG1960	acyl-CoA dehydrogenase activity
FNS06_RS27345	COG1309	transcriptional regulator
FNS06_RS27350	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
FNS06_RS27385	COG0765	amino acid transport
FNS06_RS27390	COG0765	amino acid transport
FNS06_RS27395	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
FNS06_RS27400	COG3608	succinylglutamate desuccinylase aspartoacylase
FNS06_RS27405	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FNS06_RS27435	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FNS06_RS27440	COG1272	protein, Hemolysin III
FNS06_RS27445	COG1028	Short-chain dehydrogenase reductase Sdr
FNS06_RS27465	COG0154	amidase activity
FNS06_RS27475	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FNS06_RS27485	COG0534	Mate efflux family protein
FNS06_RS27490	COG0028	Belongs to the TPP enzyme family
FNS06_RS27495	COG1250	3-hydroxyacyl-CoA dehydrogenase
FNS06_RS27495	COG1024	Enoyl-CoA hydratase
FNS06_RS27505	COG3618	amidohydrolase
FNS06_RS27510	COG0659	secondary active sulfate transmembrane transporter activity
FNS06_RS27525	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
FNS06_RS27535	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FNS06_RS27540	COG2814	Major facilitator Superfamily
FNS06_RS27560	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
FNS06_RS27565	COG2226	methyltransferase
FNS06_RS27570	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FNS06_RS27580	COG1024	Enoyl-CoA hydratase
FNS06_RS27585	COG0268	Binds directly to 16S ribosomal RNA