locus-tag	class	description
B1L07_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
B1L07_RS00010	COG0592	DNA-directed DNA polymerase activity
B1L07_RS00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
B1L07_RS00020	COG0187	DNA topoisomerase II activity
B1L07_RS00030	COG0501	Belongs to the peptidase M48B family
B1L07_RS00075	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
B1L07_RS00090	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
B1L07_RS00105	COG4772	TonB-dependent receptor
B1L07_RS00115	COG0800	Aldolase
B1L07_RS00120	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
B1L07_RS00125	COG4771	TonB-dependent receptor
B1L07_RS00140	COG2272	Belongs to the type-B carboxylesterase lipase family
B1L07_RS00170	COG1609	Transcriptional regulator
B1L07_RS00175	COG1028	Short-chain dehydrogenase reductase Sdr
B1L07_RS00185	COG0302	gtp cyclohydrolase
B1L07_RS00195	COG4206	TonB-dependent receptor
B1L07_RS00215	COG1262	PFAM Formylglycine-generating sulfatase enzyme
B1L07_RS00220	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
B1L07_RS00225	COG0676	glucose-6-phosphate 1-epimerase activity
B1L07_RS00230	COG3135	benzoate transporter
B1L07_RS00265	COG0493	'glutamate synthase
B1L07_RS00270	COG0070	glutamate synthase
B1L07_RS00270	COG0069	glutamate synthase activity
B1L07_RS00270	COG0067	glutamate synthase
B1L07_RS00335	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
B1L07_RS00370	COG0738	Major facilitator superfamily
B1L07_RS00375	COG3254	rhamnose metabolic process
B1L07_RS00380	COG1028	Short-chain dehydrogenase reductase Sdr
B1L07_RS00385	COG3618	amidohydrolase
B1L07_RS00395	COG4948	Mandelate Racemase Muconate Lactonizing
B1L07_RS00400	COG0179	Fumarylacetoacetate (FAA) hydrolase
B1L07_RS00405	COG1028	Short-chain dehydrogenase reductase Sdr
B1L07_RS00470	COG0714	Associated with various cellular activities
B1L07_RS00505	COG3550	peptidyl-serine autophosphorylation
B1L07_RS00530	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
B1L07_RS00540	COG2062	phosphohistidine phosphatase, SixA
B1L07_RS00550	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
B1L07_RS00565	COG2199	diguanylate cyclase activity
B1L07_RS00565	COG2200	EAL domain
B1L07_RS00565	COG2202	Pas domain
B1L07_RS00595	COG1968	undecaprenyl-diphosphatase activity
B1L07_RS00600	COG0174	glutamine synthetase
B1L07_RS00615	COG3852	Histidine kinase
B1L07_RS00620	COG2204	response regulator
B1L07_RS00630	COG2032	superoxide dismutase activity
B1L07_RS00635	COG2032	superoxide dismutase activity
B1L07_RS00645	COG0183	Belongs to the thiolase family
B1L07_RS00690	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
B1L07_RS00695	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
B1L07_RS00700	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
B1L07_RS00710	COG1028	Short-chain dehydrogenase reductase Sdr
B1L07_RS00745	COG0454	-acetyltransferase
B1L07_RS00770	COG0129	dihydroxy-acid dehydratase activity
B1L07_RS00780	COG0754	glutathionylspermidine amidase activity
B1L07_RS00795	COG0714	Associated with various cellular activities
B1L07_RS00825	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
B1L07_RS00860	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
B1L07_RS00880	COG1028	Short-chain dehydrogenase reductase Sdr
B1L07_RS00895	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
B1L07_RS00900	COG1040	competence protein
B1L07_RS00920	COG2207	Transcriptional regulator
B1L07_RS00930	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
B1L07_RS00955	COG0606	chelatase, subunit chli
B1L07_RS00960	COG2960	long-chain fatty acid transporting porin activity
B1L07_RS00985	COG1166	arginine decarboxylase activity
B1L07_RS00990	COG4221	oxidoreductase activity
B1L07_RS01000	COG0018	arginyl-trna synthetase
B1L07_RS01010	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
B1L07_RS01030	COG2205	protein histidine kinase activity
B1L07_RS01040	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
B1L07_RS01045	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
B1L07_RS01065	COG0708	Exodeoxyribonuclease III
B1L07_RS01070	COG2223	nitrite transmembrane transporter activity
B1L07_RS01085	COG0739	heme binding
B1L07_RS01130	COG4942	peptidase
B1L07_RS01135	COG0793	Belongs to the peptidase S41A family
B1L07_RS01170	COG1565	acr, cog1565
B1L07_RS01170	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
B1L07_RS01180	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
B1L07_RS01225	COG0358	DNA primase activity
B1L07_RS01235	COG1610	YqeY-like protein
B1L07_RS01245	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
B1L07_RS01250	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
B1L07_RS01255	COG0668	transmembrane transport
B1L07_RS01270	COG2133	pyrroloquinoline quinone binding
B1L07_RS01275	COG1301	dicarboxylic acid transport
B1L07_RS01285	COG1737	Transcriptional regulator
B1L07_RS01300	COG4948	Mandelate Racemase Muconate Lactonizing
B1L07_RS01320	COG0019	diaminopimelate decarboxylase activity
B1L07_RS01325	COG3023	N-Acetylmuramoyl-L-alanine amidase
B1L07_RS01340	COG3023	N-Acetylmuramoyl-L-alanine amidase
B1L07_RS01345	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
B1L07_RS01350	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
B1L07_RS01375	COG5383	Protein conserved in bacteria
B1L07_RS01385	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
B1L07_RS01390	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
B1L07_RS01395	COG1473	amidohydrolase
B1L07_RS01400	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
B1L07_RS01400	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
B1L07_RS01435	COG3118	belongs to the thioredoxin family
B1L07_RS01440	COG0513	Belongs to the DEAD box helicase family
B1L07_RS01445	COG2884	Cell division ATP-binding protein ftsE
B1L07_RS01450	COG2177	Part of the ABC transporter FtsEX involved in
B1L07_RS01455	COG2201	protein-glutamate methylesterase activity
B1L07_RS01465	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
B1L07_RS01475	COG1252	NADH dehydrogenase
B1L07_RS01485	COG0625	glutathione transferase activity
B1L07_RS01495	COG3537	Alpha-1,2-mannosidase
B1L07_RS01500	COG1609	Transcriptional regulator
B1L07_RS01510	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
B1L07_RS01520	COG3250	beta-galactosidase activity
B1L07_RS01535	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
B1L07_RS01550	COG0534	Mate efflux family protein
B1L07_RS01555	COG0616	signal peptide processing
B1L07_RS01565	COG1028	Short-chain dehydrogenase reductase Sdr
B1L07_RS01575	COG0009	L-threonylcarbamoyladenylate synthase
B1L07_RS01580	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
B1L07_RS01580	COG1754	DNA topoisomerase type I activity
B1L07_RS01585	COG1714	RDD family
B1L07_RS01595	COG2922	Belongs to the Smg family
B1L07_RS01600	COG0758	DNA mediated transformation
B1L07_RS01610	COG0242	peptide deformylase activity
B1L07_RS01615	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
B1L07_RS01620	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
B1L07_RS01620	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
B1L07_RS01630	COG1215	transferase activity, transferring glycosyl groups
B1L07_RS01675	COG1490	D-aminoacyl-tRNA deacylase activity
B1L07_RS01680	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
B1L07_RS01725	COG3275	phosphorelay sensor kinase activity
B1L07_RS01735	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
B1L07_RS01760	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
B1L07_RS01770	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
B1L07_RS01780	COG1595	DNA-templated transcription, initiation
B1L07_RS01790	COG0302	gtp cyclohydrolase
B1L07_RS01820	COG2200	EAL domain
B1L07_RS01825	COG3706	GGDEF domain
B1L07_RS01835	COG5002	protein histidine kinase activity
B1L07_RS01835	COG5001	Diguanylate cyclase
B1L07_RS01870	COG3795	YCII-related domain
B1L07_RS01875	COG3795	YCII-related domain
B1L07_RS01890	COG5507	3-demethylubiquinone-9 3-methyltransferase
B1L07_RS01895	COG4941	Belongs to the sigma-70 factor family
B1L07_RS01905	COG2972	Histidine kinase
B1L07_RS01930	COG3590	peptidase
B1L07_RS01940	COG0583	DNA-binding transcription factor activity
B1L07_RS01945	COG3384	dioxygenase
B1L07_RS01950	COG0025	NhaP-type Na H and K H
B1L07_RS02030	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
B1L07_RS02040	COG1666	GTP binding
B1L07_RS02050	COG0697	spore germination
B1L07_RS02060	COG2011	ABC-type metal ion transport system permease component
B1L07_RS02065	COG1464	Belongs to the NlpA lipoprotein family
B1L07_RS02085	COG0508	dehydrogenase complex catalyzes the overall conversion of
B1L07_RS02090	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
B1L07_RS02115	COG0356	it plays a direct role in the translocation of protons across the membrane
B1L07_RS02125	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
B1L07_RS02130	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
B1L07_RS02135	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
B1L07_RS02140	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
B1L07_RS02145	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
B1L07_RS02150	COG0355	proton-transporting ATP synthase activity, rotational mechanism
B1L07_RS02160	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
B1L07_RS02165	COG4191	Histidine kinase
B1L07_RS02175	COG1136	(ABC) transporter
B1L07_RS02175	COG0577	efflux transmembrane transporter activity
B1L07_RS02190	COG1136	(ABC) transporter
B1L07_RS02190	COG0577	efflux transmembrane transporter activity
B1L07_RS02200	COG1136	(ABC) transporter
B1L07_RS02200	COG0577	efflux transmembrane transporter activity
B1L07_RS02205	COG1136	(ABC) transporter
B1L07_RS02205	COG0577	efflux transmembrane transporter activity
B1L07_RS02210	COG0577	efflux transmembrane transporter activity
B1L07_RS02210	COG1136	(ABC) transporter
B1L07_RS02215	COG1136	(ABC) transporter
B1L07_RS02215	COG0577	efflux transmembrane transporter activity
B1L07_RS02220	COG1136	(ABC) transporter
B1L07_RS02230	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
B1L07_RS02240	COG3710	Transcriptional regulator
B1L07_RS02240	COG0457	Tetratricopeptide repeat
B1L07_RS02290	COG2132	Multicopper oxidase
B1L07_RS02355	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
B1L07_RS02360	COG0546	phosphoglycolate phosphatase activity
B1L07_RS02365	COG4206	TonB-dependent receptor
B1L07_RS02370	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
B1L07_RS02380	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
B1L07_RS02390	COG1956	GAF domain-containing protein
B1L07_RS02400	COG0720	synthase
B1L07_RS02415	COG0513	Belongs to the DEAD box helicase family
B1L07_RS02425	COG0625	glutathione transferase activity
B1L07_RS02455	COG0626	cystathionine gamma-synthase activity
B1L07_RS02465	COG1450	Type ii and iii secretion system protein
B1L07_RS02520	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
B1L07_RS02545	COG1216	Glycosyl transferase, family 2
B1L07_RS02545	COG0438	transferase activity, transferring glycosyl groups
B1L07_RS02555	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
B1L07_RS02560	COG2076	Multidrug Resistance protein
B1L07_RS02575	COG0318	PFAM AMP-dependent synthetase and ligase
B1L07_RS02580	COG3321	synthase
B1L07_RS02580	COG0300	oxidoreductase activity
B1L07_RS02580	COG0318	PFAM AMP-dependent synthetase and ligase
B1L07_RS02580	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
B1L07_RS02580	COG1028	Short-chain dehydrogenase reductase Sdr
B1L07_RS02585	COG1028	Short-chain dehydrogenase reductase Sdr
B1L07_RS02600	COG0463	Glycosyl transferase, family 2
B1L07_RS02630	COG1091	dTDP-4-dehydrorhamnose reductase activity
B1L07_RS02640	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
B1L07_RS02660	COG2409	Drug exporters of the RND superfamily
B1L07_RS02680	COG0181	hydroxymethylbilane synthase activity
B1L07_RS02705	COG1505	serine-type exopeptidase activity
B1L07_RS02710	COG0436	Aminotransferase
B1L07_RS02720	COG2832	Protein of unknown function (DUF454)
B1L07_RS02730	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
B1L07_RS02755	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
B1L07_RS02765	COG1309	transcriptional regulator
B1L07_RS02770	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
B1L07_RS02775	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
B1L07_RS02790	COG2226	methyltransferase
B1L07_RS02815	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
B1L07_RS02820	COG1077	Cell shape determining protein MreB Mrl
B1L07_RS02830	COG0768	penicillin binding
B1L07_RS02835	COG0772	Belongs to the SEDS family
B1L07_RS02840	COG2951	lytic endotransglycosylase activity
B1L07_RS02850	COG1686	Belongs to the peptidase S11 family
B1L07_RS02865	COG2921	Belongs to the UPF0250 family
B1L07_RS02870	COG0321	lipoyl(octanoyl) transferase activity
B1L07_RS02895	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
B1L07_RS02910	COG0784	Response regulator, receiver
B1L07_RS02915	COG4191	Histidine kinase
B1L07_RS02920	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
B1L07_RS02940	COG0662	Cupin 2, conserved barrel domain protein
B1L07_RS02945	COG3525	Glycosyl hydrolase, family 20, catalytic domain
B1L07_RS02950	COG3876	Protein conserved in bacteria
B1L07_RS02955	COG3525	Glycosyl hydrolase, family 20, catalytic domain
B1L07_RS02970	COG0837	glucose binding
B1L07_RS02975	COG3525	Glycosyl hydrolase, family 20, catalytic domain
B1L07_RS02985	COG0837	glucose binding
B1L07_RS02990	COG0738	Major facilitator superfamily
B1L07_RS03000	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
B1L07_RS03005	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
B1L07_RS03020	COG0617	tRNA 3'-terminal CCA addition
B1L07_RS03060	COG0218	Necessary for normal cell division and for the maintenance of normal septation
B1L07_RS03065	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
B1L07_RS03120	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
B1L07_RS03140	COG1307	EDD domain protein, DegV family
B1L07_RS03145	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
B1L07_RS03150	COG3964	amidohydrolase
B1L07_RS03160	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
B1L07_RS03170	COG0513	Belongs to the DEAD box helicase family
B1L07_RS03190	COG0436	Aminotransferase
B1L07_RS03195	COG1162	GTPase activity
B1L07_RS03205	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
B1L07_RS03220	COG0583	DNA-binding transcription factor activity
B1L07_RS03225	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
B1L07_RS03235	COG0405	Gamma-glutamyltransferase
B1L07_RS03240	COG0786	glutamate:sodium symporter activity
B1L07_RS03250	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
B1L07_RS03255	COG1737	Transcriptional regulator
B1L07_RS03260	COG2610	gluconate transmembrane transporter activity
B1L07_RS03275	COG2197	response regulator
B1L07_RS03285	COG3916	Acyl-homoserine-lactone synthase
B1L07_RS03295	COG0297	glycogen (starch) synthase activity
B1L07_RS03305	COG1560	Kdo2-lipid A biosynthetic process
B1L07_RS03310	COG1519	Transferase
B1L07_RS03315	COG1538	Outer membrane efflux protein
B1L07_RS03320	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
B1L07_RS03340	COG3300	MHYT domain
B1L07_RS03340	COG5001	Diguanylate cyclase
B1L07_RS03365	COG0778	Nitroreductase
B1L07_RS03425	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
B1L07_RS03430	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
B1L07_RS03450	COG1295	ribonuclease BN
B1L07_RS03455	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
B1L07_RS03485	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
B1L07_RS03490	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
B1L07_RS03505	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
B1L07_RS03515	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
B1L07_RS03525	COG0193	aminoacyl-tRNA hydrolase activity
B1L07_RS03530	COG0012	GTP binding
B1L07_RS03545	COG1446	asparaginase
B1L07_RS03565	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
B1L07_RS03580	COG0250	Participates in transcription elongation, termination and antitermination
B1L07_RS03585	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
B1L07_RS03590	COG0081	regulation of translation
B1L07_RS03600	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
B1L07_RS03605	COG0222	ribosome binding
B1L07_RS03610	COG0085	RNA polymerase activity
B1L07_RS03615	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
B1L07_RS03625	COG0049	tRNA binding
B1L07_RS03635	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
B1L07_RS03640	COG0583	DNA-binding transcription factor activity
B1L07_RS03645	COG2814	Major facilitator Superfamily
B1L07_RS03660	COG0051	transcription antitermination factor activity, RNA binding
B1L07_RS03665	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
B1L07_RS03670	COG0088	Forms part of the polypeptide exit tunnel
B1L07_RS03675	COG0089	rRNA binding
B1L07_RS03680	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
B1L07_RS03685	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
B1L07_RS03690	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
B1L07_RS03695	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
B1L07_RS03700	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
B1L07_RS03705	COG0255	Belongs to the universal ribosomal protein uL29 family
B1L07_RS03710	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
B1L07_RS03720	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
B1L07_RS03725	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
B1L07_RS03730	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
B1L07_RS03735	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
B1L07_RS03745	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
B1L07_RS03750	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
B1L07_RS03755	COG1841	ribosomal large subunit assembly
B1L07_RS03760	COG0200	Binds to the 23S rRNA
B1L07_RS03765	COG0201	protein transport
B1L07_RS03770	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
B1L07_RS03780	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
B1L07_RS03785	COG0202	RNA polymerase activity
B1L07_RS03790	COG0203	ribosomal protein L17
B1L07_RS03795	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
B1L07_RS03800	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
B1L07_RS03810	COG0154	amidase activity
B1L07_RS03820	COG1217	gtp-binding protein TYPA
B1L07_RS03825	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
B1L07_RS03860	COG0745	RESPONSE REGULATOR receiver
B1L07_RS03865	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
B1L07_RS03875	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
B1L07_RS03880	COG0625	glutathione transferase activity
B1L07_RS03890	COG1902	pentaerythritol trinitrate reductase activity
B1L07_RS03890	COG0446	pyridine nucleotide-disulphide oxidoreductase
B1L07_RS03910	COG1187	pseudouridine synthase activity
B1L07_RS03940	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
B1L07_RS03945	COG4208	sulfate ABC transporter
B1L07_RS03950	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
B1L07_RS03960	COG1063	alcohol dehydrogenase
B1L07_RS03975	COG0588	phosphoglycerate mutase activity
B1L07_RS03985	COG0285	dihydrofolate synthase activity
B1L07_RS04005	COG2833	Protein of unknown function (DUF455)
B1L07_RS04015	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
B1L07_RS04025	COG0438	transferase activity, transferring glycosyl groups
B1L07_RS04030	COG0248	Ppx GppA phosphatase
B1L07_RS04035	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
B1L07_RS04040	COG5002	protein histidine kinase activity
B1L07_RS04050	COG4783	chaperone-mediated protein folding
B1L07_RS04065	COG0473	3-isopropylmalate dehydrogenase activity
B1L07_RS04105	COG0544	peptidyl-prolyl cis-trans isomerase activity
B1L07_RS04115	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
B1L07_RS04150	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
B1L07_RS04155	COG3942	CHAP domain
B1L07_RS04155	COG1388	LysM domain
B1L07_RS04175	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
B1L07_RS04180	COG0631	protein serine/threonine phosphatase activity
B1L07_RS04200	COG3642	lipopolysaccharide core region biosynthetic process
B1L07_RS04205	COG1234	tRNA 3'-trailer cleavage
B1L07_RS04220	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
B1L07_RS04230	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
B1L07_RS04235	COG0537	adenosine 5'-monophosphoramidase activity
B1L07_RS04260	COG0714	Associated with various cellular activities
B1L07_RS04285	COG1399	metal-binding, possibly nucleic acid-binding protein
B1L07_RS04290	COG0333	Belongs to the bacterial ribosomal protein bL32 family
B1L07_RS04295	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
B1L07_RS04305	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
B1L07_RS04310	COG1028	Short-chain dehydrogenase reductase Sdr
B1L07_RS04320	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
B1L07_RS04325	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
B1L07_RS04330	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
B1L07_RS04355	COG3540	Alkaline phosphatase
B1L07_RS04415	COG2818	Glycosylase
B1L07_RS04420	COG1678	Uncharacterized ACR, COG1678
B1L07_RS04430	COG0540	Belongs to the ATCase OTCase family
B1L07_RS04455	COG2239	Acts as a magnesium transporter
B1L07_RS04460	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
B1L07_RS04475	COG1660	Displays ATPase and GTPase activities
B1L07_RS04485	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
B1L07_RS04500	COG1137	ATPase activity
B1L07_RS04515	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
B1L07_RS04530	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
B1L07_RS04540	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
B1L07_RS04560	COG3011	Protein conserved in bacteria
B1L07_RS04565	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
B1L07_RS04630	COG4771	TonB-dependent receptor
B1L07_RS04640	COG1595	DNA-templated transcription, initiation
B1L07_RS04645	COG0542	response to heat
B1L07_RS04665	COG0583	DNA-binding transcription factor activity
B1L07_RS04680	COG0488	(ABC) transporter
B1L07_RS04710	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
B1L07_RS04740	COG0217	transcriptional regulatory protein
B1L07_RS04750	COG0632	four-way junction helicase activity
B1L07_RS04765	COG0824	Thioesterase
B1L07_RS04775	COG0848	biopolymer transport protein
B1L07_RS04790	COG2885	chlorophyll binding
B1L07_RS04800	COG0602	queuosine metabolic process
B1L07_RS04805	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
B1L07_RS04820	COG0515	serine threonine protein kinase
B1L07_RS04820	COG2815	serine threonine protein kinase
B1L07_RS04825	COG0514	ATP-dependent DNA helicase (RecQ)
B1L07_RS04830	COG0783	Belongs to the Dps family
B1L07_RS04835	COG1643	Atp-dependent helicase
B1L07_RS04850	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
B1L07_RS04865	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
B1L07_RS04875	COG1199	ATP-dependent helicase activity
B1L07_RS04890	COG0384	phenazine biosynthesis protein PhzF
B1L07_RS04895	COG0384	phenazine biosynthesis protein PhzF
B1L07_RS04900	COG0527	aspartate kinase activity
B1L07_RS04910	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
B1L07_RS04925	COG0142	geranyltranstransferase activity
B1L07_RS04940	COG1082	Xylose isomerase domain protein TIM barrel
B1L07_RS04945	COG2211	Major facilitator Superfamily
B1L07_RS04945	COG2190	(PTS) system
B1L07_RS04975	COG0629	single-stranded DNA binding
B1L07_RS04980	COG0431	NADPH-dependent FMN reductase
B1L07_RS05005	COG2197	response regulator
B1L07_RS05015	COG4948	Mandelate Racemase Muconate Lactonizing
B1L07_RS05025	COG4771	TonB-dependent receptor
B1L07_RS05045	COG3104	oligopeptide transport
B1L07_RS05050	COG1297	OPT oligopeptide transporter protein
B1L07_RS05070	COG2879	small protein
B1L07_RS05075	COG1966	Carbon starvation protein
B1L07_RS05090	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
B1L07_RS05100	COG1515	deoxyribonuclease V activity
B1L07_RS05105	COG0588	phosphoglycerate mutase activity
B1L07_RS05145	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
B1L07_RS05155	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
B1L07_RS05160	COG0745	RESPONSE REGULATOR receiver
B1L07_RS05165	COG2205	protein histidine kinase activity
B1L07_RS05170	COG5001	Diguanylate cyclase
B1L07_RS05170	COG5002	protein histidine kinase activity
B1L07_RS05175	COG4452	Inner membrane protein CreD
B1L07_RS05205	COG0824	Thioesterase
B1L07_RS05220	COG0211	Belongs to the bacterial ribosomal protein bL27 family
B1L07_RS05230	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
B1L07_RS05250	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
B1L07_RS05260	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
B1L07_RS05270	COG4206	TonB-dependent receptor
B1L07_RS05295	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
B1L07_RS05300	COG1845	cytochrome c oxidase, subunit III
B1L07_RS05305	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
B1L07_RS05325	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
B1L07_RS05330	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
B1L07_RS05335	COG2070	2-Nitropropane dioxygenase
B1L07_RS05350	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
B1L07_RS05355	COG0336	Belongs to the RNA methyltransferase TrmD family
B1L07_RS05360	COG0335	large ribosomal subunit rRNA binding
B1L07_RS05365	COG1349	DNA-binding transcription factor activity
B1L07_RS05375	COG1940	carbohydrate kinase activity
B1L07_RS05380	COG2222	sugar isomerase
B1L07_RS05385	COG1501	Belongs to the glycosyl hydrolase 31 family
B1L07_RS05395	COG0673	inositol 2-dehydrogenase activity
B1L07_RS05400	COG0534	Mate efflux family protein
B1L07_RS05455	COG0531	amino acid
B1L07_RS05470	COG3706	GGDEF domain
B1L07_RS05475	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
B1L07_RS05505	COG2217	Heavy metal translocating P-type atpase
B1L07_RS05525	COG2010	Cytochrome c
B1L07_RS05540	COG3278	Belongs to the heme-copper respiratory oxidase family
B1L07_RS05545	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
B1L07_RS05550	COG1024	Enoyl-CoA hydratase
B1L07_RS05550	COG1250	3-hydroxyacyl-CoA dehydrogenase
B1L07_RS05570	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
B1L07_RS05580	COG0681	Belongs to the peptidase S26 family
B1L07_RS05595	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
B1L07_RS05610	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
B1L07_RS05615	COG2954	triphosphatase activity
B1L07_RS05620	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
B1L07_RS05625	COG1472	Belongs to the glycosyl hydrolase 3 family
B1L07_RS05630	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
B1L07_RS05635	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
B1L07_RS05640	COG1278	Cold shock
B1L07_RS05645	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
B1L07_RS05650	COG1960	acyl-CoA dehydrogenase activity
B1L07_RS05670	COG0183	Belongs to the thiolase family
B1L07_RS05690	COG5001	Diguanylate cyclase
B1L07_RS05690	COG3300	MHYT domain
B1L07_RS05695	COG1619	proteins homologs of microcin C7 resistance protein MccF
B1L07_RS05700	COG1228	amidohydrolase
B1L07_RS05725	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
B1L07_RS05730	COG3447	MASE1 domain protein
B1L07_RS05730	COG5002	protein histidine kinase activity
B1L07_RS05730	COG5001	Diguanylate cyclase
B1L07_RS05735	COG0204	Acyl-transferase
B1L07_RS05760	COG2814	Major facilitator Superfamily
B1L07_RS05780	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
B1L07_RS05800	COG1451	nucleotide metabolic process
B1L07_RS05810	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
B1L07_RS05840	COG2824	Alkylphosphonate utilization operon protein PhnA
B1L07_RS05875	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
B1L07_RS05875	COG0392	lysyltransferase activity
B1L07_RS05885	COG0251	oxidation-reduction process
B1L07_RS05910	COG2733	membrane
B1L07_RS05925	COG3759	membrane
B1L07_RS05940	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
B1L07_RS05955	COG0477	Major facilitator Superfamily
B1L07_RS05960	COG2703	oxygen carrier activity
B1L07_RS05970	COG0745	RESPONSE REGULATOR receiver
B1L07_RS06000	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
B1L07_RS06010	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
B1L07_RS06020	COG1176	ABC-type spermidine putrescine transport system, permease component I
B1L07_RS06025	COG1177	transmembrane transport
B1L07_RS06030	COG1012	belongs to the aldehyde dehydrogenase family
B1L07_RS06055	COG4535	Mg2 and Co2 transporter CorC
B1L07_RS06070	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
B1L07_RS06080	COG1702	phosphate starvation-inducible protein PhoH
B1L07_RS06095	COG1131	(ABC) transporter
B1L07_RS06100	COG0842	Transport permease protein
B1L07_RS06110	COG0741	lytic transglycosylase activity
B1L07_RS06115	COG0723	plastoquinol--plastocyanin reductase activity
B1L07_RS06120	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
B1L07_RS06125	COG2857	Cytochrome c1
B1L07_RS06130	COG0625	glutathione transferase activity
B1L07_RS06135	COG2969	positive regulation of protein catabolic process
B1L07_RS06170	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
B1L07_RS06180	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
B1L07_RS06185	COG1028	Short-chain dehydrogenase reductase Sdr
B1L07_RS06190	COG2095	MarC family integral membrane protein
B1L07_RS06200	COG1611	Belongs to the LOG family
B1L07_RS06205	COG3275	phosphorelay sensor kinase activity
B1L07_RS06255	COG0556	nucleotide-excision repair
B1L07_RS06265	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
B1L07_RS06270	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
B1L07_RS06285	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
B1L07_RS06315	COG0348	domain, Protein
B1L07_RS06340	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
B1L07_RS06345	COG0069	glutamate synthase activity
B1L07_RS06350	COG0493	'glutamate synthase
B1L07_RS06380	COG1253	flavin adenine dinucleotide binding
B1L07_RS06390	COG0306	phosphate transporter
B1L07_RS06410	COG0504	CTP synthase activity
B1L07_RS06415	COG2877	3-deoxy-8-phosphooctulonate synthase activity
B1L07_RS06420	COG0148	phosphopyruvate hydratase activity
B1L07_RS06425	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
B1L07_RS06430	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
B1L07_RS06435	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
B1L07_RS06440	COG0585	pseudouridine synthase activity
B1L07_RS06445	COG2840	Smr protein MutS2
B1L07_RS06450	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
B1L07_RS06460	COG1238	metal cluster binding
B1L07_RS06480	COG1534	Rna-binding protein
B1L07_RS06485	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
B1L07_RS06490	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
B1L07_RS06495	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
B1L07_RS06500	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
B1L07_RS06510	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
B1L07_RS06515	COG0688	phosphatidylethanolamine metabolic process
B1L07_RS06525	COG2890	protein-(glutamine-N5) methyltransferase activity
B1L07_RS06530	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
B1L07_RS06535	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
B1L07_RS06540	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
B1L07_RS06555	COG0101	tRNA pseudouridine synthase activity
B1L07_RS06570	COG0133	tryptophan synthase activity
B1L07_RS06580	COG0159	tryptophan synthase activity
B1L07_RS06585	COG2755	lipolytic protein G-D-S-L family
B1L07_RS06585	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
B1L07_RS06590	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
B1L07_RS06600	COG0726	polysaccharide deacetylase
B1L07_RS06615	COG0149	triose-phosphate isomerase activity
B1L07_RS06630	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
B1L07_RS06635	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
B1L07_RS06640	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
B1L07_RS06645	COG0649	NAD binding
B1L07_RS06650	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
B1L07_RS06655	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
B1L07_RS06660	COG1034	ATP synthesis coupled electron transport
B1L07_RS06695	COG1007	ATP synthesis coupled electron transport
B1L07_RS06705	COG0779	Required for maturation of 30S ribosomal subunits
B1L07_RS06715	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
B1L07_RS06720	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
B1L07_RS06730	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
B1L07_RS06750	COG0848	biopolymer transport protein
B1L07_RS06760	COG1663	tetraacyldisaccharide 4'-kinase activity
B1L07_RS06765	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
B1L07_RS06770	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
B1L07_RS06780	COG0322	excinuclease ABC activity
B1L07_RS06805	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
B1L07_RS06835	COG3712	iron ion homeostasis
B1L07_RS06840	COG1228	amidohydrolase
B1L07_RS06845	COG1473	amidohydrolase
B1L07_RS06850	COG3040	lipid binding
B1L07_RS06875	COG1262	PFAM Formylglycine-generating sulfatase enzyme
B1L07_RS06885	COG1570	exodeoxyribonuclease VII activity
B1L07_RS06890	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
B1L07_RS06895	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
B1L07_RS06895	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
B1L07_RS06900	COG0802	atpase or kinase
B1L07_RS06905	COG0860	N-Acetylmuramoyl-L-alanine amidase
B1L07_RS06930	COG1028	Short-chain dehydrogenase reductase Sdr
B1L07_RS06940	COG0501	Belongs to the peptidase M48B family
B1L07_RS06965	COG3300	MHYT domain
B1L07_RS06965	COG5001	Diguanylate cyclase
B1L07_RS06970	COG1509	lysine 2,3-aminomutase activity
B1L07_RS06975	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
B1L07_RS06980	COG3548	integral membrane protein
B1L07_RS06990	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
B1L07_RS07025	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
B1L07_RS07045	COG2166	iron-sulfur cluster assembly
B1L07_RS07060	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
B1L07_RS07065	COG0137	argininosuccinate synthase activity
B1L07_RS07075	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
B1L07_RS07080	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
B1L07_RS07095	COG0165	Argininosuccinate lyase
B1L07_RS07135	COG1294	oxidase, subunit
B1L07_RS07150	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
B1L07_RS07155	COG1793	dna ligase
B1L07_RS07165	COG2226	methyltransferase
B1L07_RS07170	COG4235	cytochrome complex assembly
B1L07_RS07175	COG3088	subunit of a heme lyase
B1L07_RS07180	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
B1L07_RS07190	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
B1L07_RS07225	COG1309	transcriptional regulator
B1L07_RS07240	COG0436	Aminotransferase
B1L07_RS07275	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
B1L07_RS07280	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
B1L07_RS07285	COG2350	Protein conserved in bacteria
B1L07_RS07325	COG0395	ABC-type sugar transport system, permease component
B1L07_RS07340	COG0800	Aldolase
B1L07_RS07360	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
B1L07_RS07385	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
B1L07_RS07400	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
B1L07_RS07415	COG1136	(ABC) transporter
B1L07_RS07430	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
B1L07_RS07440	COG0552	protein localization to endoplasmic reticulum
B1L07_RS07450	COG0326	Molecular chaperone. Has ATPase activity
B1L07_RS07455	COG0742	ribosomal rna small subunit methyltransferase
B1L07_RS07460	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
B1L07_RS07470	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
B1L07_RS07475	COG0405	Gamma-glutamyltransferase
B1L07_RS07495	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
B1L07_RS07500	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
B1L07_RS07515	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
B1L07_RS07535	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
B1L07_RS07590	COG0583	DNA-binding transcription factor activity
B1L07_RS07620	COG1522	sequence-specific DNA binding
B1L07_RS07625	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
B1L07_RS07630	COG0343	queuine tRNA-ribosyltransferase activity
B1L07_RS07635	COG1862	Preprotein translocase
B1L07_RS07645	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
B1L07_RS07650	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
B1L07_RS07655	COG2200	EAL domain
B1L07_RS07675	COG1278	Cold shock
B1L07_RS07680	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
B1L07_RS07690	COG0513	Belongs to the DEAD box helicase family
B1L07_RS07700	COG0583	DNA-binding transcription factor activity
B1L07_RS07735	COG3104	oligopeptide transport
B1L07_RS07755	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
B1L07_RS07760	COG0339	signal peptide processing
B1L07_RS07765	COG0386	Belongs to the glutathione peroxidase family
B1L07_RS07770	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
B1L07_RS07790	COG2860	membrane
B1L07_RS07795	COG2860	membrane
B1L07_RS07820	COG1393	Belongs to the ArsC family
B1L07_RS07850	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
B1L07_RS07855	COG0084	hydrolase, TatD family'
B1L07_RS07885	COG1051	belongs to the nudix hydrolase family
B1L07_RS07890	COG1183	phosphatidylcholine synthase activity
B1L07_RS07900	COG3243	poly(R)-hydroxyalkanoic acid synthase
B1L07_RS07970	COG1028	Short-chain dehydrogenase reductase Sdr
B1L07_RS07975	COG1335	isochorismatase
B1L07_RS07995	COG2823	Periplasmic or secreted lipoprotein
B1L07_RS08050	COG3920	Histidine kinase
B1L07_RS08065	COG1064	alcohol dehydrogenase
B1L07_RS08075	COG1473	amidohydrolase
B1L07_RS08080	COG1595	DNA-templated transcription, initiation
B1L07_RS08105	COG0840	transmembrane signaling receptor activity
B1L07_RS08110	COG3300	MHYT domain
B1L07_RS08110	COG5001	Diguanylate cyclase
B1L07_RS08120	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
B1L07_RS08190	COG3142	Participates in the control of copper homeostasis
B1L07_RS08195	COG1446	asparaginase
B1L07_RS08200	COG0837	glucose binding
B1L07_RS08205	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
B1L07_RS08210	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
B1L07_RS08220	COG1674	ftsk spoiiie
B1L07_RS08225	COG0492	ferredoxin-NADP+ reductase activity
B1L07_RS08230	COG1408	metallophosphoesterase
B1L07_RS08250	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
B1L07_RS08260	COG0542	response to heat
B1L07_RS08280	COG0482	sulfurtransferase activity
B1L07_RS08285	COG2915	High frequency lysogenization protein hflD homolog
B1L07_RS08315	COG5002	protein histidine kinase activity
B1L07_RS08335	COG0835	chemotaxis
B1L07_RS08335	COG0784	Response regulator, receiver
B1L07_RS08350	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
B1L07_RS08360	COG4787	bacterial-type flagellum-dependent cell motility
B1L07_RS08370	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
B1L07_RS08385	COG1256	bacterial-type flagellum assembly
B1L07_RS08435	COG2201	protein-glutamate methylesterase activity
B1L07_RS08445	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
B1L07_RS08450	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
B1L07_RS08450	COG0463	Glycosyl transferase, family 2
B1L07_RS08465	COG1215	transferase activity, transferring glycosyl groups
B1L07_RS08485	COG1677	Flagellar hook-basal body complex protein FliE
B1L07_RS08495	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
B1L07_RS08535	COG3190	flagellar
B1L07_RS08595	COG0643	Histidine kinase
B1L07_RS08595	COG0784	Response regulator, receiver
B1L07_RS08595	COG2198	Histidine kinase
B1L07_RS08600	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
B1L07_RS08625	COG0745	RESPONSE REGULATOR receiver
B1L07_RS08640	COG0840	transmembrane signaling receptor activity
B1L07_RS08645	COG0840	transmembrane signaling receptor activity
B1L07_RS08650	COG0840	transmembrane signaling receptor activity
B1L07_RS08660	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
B1L07_RS08665	COG0835	chemotaxis
B1L07_RS08675	COG0840	transmembrane signaling receptor activity
B1L07_RS08680	COG0840	transmembrane signaling receptor activity
B1L07_RS08680	COG0840	transmembrane signaling receptor activity
B1L07_RS08725	COG1228	amidohydrolase
B1L07_RS08740	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
B1L07_RS08795	COG3047	cAMP biosynthetic process
B1L07_RS08795	COG2885	chlorophyll binding
B1L07_RS08805	COG0318	PFAM AMP-dependent synthetase and ligase
B1L07_RS08810	COG1024	Enoyl-CoA hydratase
B1L07_RS08815	COG0784	Response regulator, receiver
B1L07_RS08815	COG2198	Histidine kinase
B1L07_RS08815	COG2205	protein histidine kinase activity
B1L07_RS08825	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
B1L07_RS08845	COG3279	Response regulator of the LytR AlgR family
B1L07_RS08855	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
B1L07_RS08865	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
B1L07_RS08870	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
B1L07_RS08875	COG0505	Belongs to the CarA family
B1L07_RS08895	COG1918	ferrous iron import across plasma membrane
B1L07_RS08895	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
B1L07_RS08925	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
B1L07_RS08945	COG0277	FAD linked oxidase domain protein
B1L07_RS08950	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
B1L07_RS08960	COG0531	amino acid
B1L07_RS08965	COG0531	amino acid
B1L07_RS08970	COG0235	Class ii aldolase
B1L07_RS08975	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
B1L07_RS08980	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
B1L07_RS08985	COG1285	pathogenesis
B1L07_RS09000	COG0531	amino acid
B1L07_RS09020	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
B1L07_RS09020	COG0140	phosphoribosyl-ATP diphosphatase activity
B1L07_RS09040	COG0131	Imidazoleglycerol-phosphate dehydratase
B1L07_RS09040	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
B1L07_RS09045	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
B1L07_RS09050	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
B1L07_RS09055	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
B1L07_RS09065	COG0124	histidyl-tRNA synthetase
B1L07_RS09070	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
B1L07_RS09080	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
B1L07_RS09085	COG0083	homoserine kinase activity
B1L07_RS09110	COG1012	belongs to the aldehyde dehydrogenase family
B1L07_RS09125	COG0167	dihydroorotate dehydrogenase activity
B1L07_RS09150	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
B1L07_RS09155	COG1061	Type III restriction enzyme res subunit
B1L07_RS09195	COG0582	viral genome integration into host DNA
B1L07_RS09200	COG0518	GMP synthase (glutamine-hydrolyzing) activity
B1L07_RS09200	COG0519	Catalyzes the synthesis of GMP from XMP
B1L07_RS09215	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
B1L07_RS09220	COG1160	GTP binding
B1L07_RS09225	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
B1L07_RS09245	COG0820	rRNA (adenine-C2-)-methyltransferase activity
B1L07_RS09250	COG0105	UTP biosynthetic process
B1L07_RS09260	COG1024	Enoyl-CoA hydratase
B1L07_RS09260	COG1250	3-hydroxyacyl-CoA dehydrogenase
B1L07_RS09265	COG0183	Belongs to the thiolase family
B1L07_RS09295	COG0776	regulation of translation
B1L07_RS09310	COG0257	Belongs to the bacterial ribosomal protein bL36 family
B1L07_RS09320	COG2957	Belongs to the agmatine deiminase family
B1L07_RS09325	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
B1L07_RS09350	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
B1L07_RS09385	COG0316	Belongs to the HesB IscA family
B1L07_RS09385	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
B1L07_RS09390	COG2154	pterin-4-alpha-carbinolamine dehydratase
B1L07_RS09405	COG1530	ribonuclease E activity
B1L07_RS09410	COG2197	response regulator
B1L07_RS09415	COG0671	phosphoesterase, PA-phosphatase related
B1L07_RS09420	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
B1L07_RS09430	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
B1L07_RS09435	COG1028	Short-chain dehydrogenase reductase Sdr
B1L07_RS09465	COG0305	Participates in initiation and elongation during chromosome replication
B1L07_RS09475	COG0367	asparagine synthase
B1L07_RS09485	COG0625	glutathione transferase activity
B1L07_RS09500	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
B1L07_RS09520	COG0583	DNA-binding transcription factor activity
B1L07_RS09525	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
B1L07_RS09540	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
B1L07_RS09550	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
B1L07_RS09575	COG4771	TonB-dependent receptor
B1L07_RS09600	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
B1L07_RS09605	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
B1L07_RS09610	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
B1L07_RS09615	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
B1L07_RS09620	COG0617	tRNA 3'-terminal CCA addition
B1L07_RS09630	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
B1L07_RS09640	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
B1L07_RS09650	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
B1L07_RS09655	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
B1L07_RS09695	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
B1L07_RS09715	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
B1L07_RS09735	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
B1L07_RS09740	COG0360	Binds together with S18 to 16S ribosomal RNA
B1L07_RS09745	COG0316	Belongs to the HesB IscA family
B1L07_RS09750	COG0017	Asparaginyl-tRNA synthetase
B1L07_RS09765	COG2808	Putative FMN-binding domain
B1L07_RS09770	COG0288	reversible hydration of carbon dioxide
B1L07_RS09780	COG3844	kynureninase activity
B1L07_RS09785	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
B1L07_RS09790	COG2925	Exonuclease
B1L07_RS09820	COG1278	Cold shock
B1L07_RS09840	COG2902	Dehydrogenase
B1L07_RS09855	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
B1L07_RS09860	COG1960	acyl-CoA dehydrogenase activity
B1L07_RS09885	COG0583	DNA-binding transcription factor activity
B1L07_RS09895	COG2814	Major facilitator Superfamily
B1L07_RS09905	COG2900	Belongs to the SlyX family
B1L07_RS09920	COG0386	Belongs to the glutathione peroxidase family
B1L07_RS09930	COG1725	Transcriptional regulator
B1L07_RS09935	COG1131	(ABC) transporter
B1L07_RS09980	COG5001	Diguanylate cyclase
B1L07_RS09985	COG2850	peptidyl-arginine hydroxylation
B1L07_RS09995	COG0567	Dehydrogenase, E1 component
B1L07_RS10020	COG1595	DNA-templated transcription, initiation
B1L07_RS10035	COG1132	(ABC) transporter
B1L07_RS10050	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
B1L07_RS10055	COG0484	heat shock protein binding
B1L07_RS10060	COG0443	Heat shock 70 kDa protein
B1L07_RS10065	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
B1L07_RS10070	COG0497	DNA recombination
B1L07_RS10080	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
B1L07_RS10095	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
B1L07_RS10110	COG0582	viral genome integration into host DNA
B1L07_RS10125	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
B1L07_RS10135	COG2137	regulation of response to DNA damage stimulus
B1L07_RS10140	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
B1L07_RS10145	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
B1L07_RS10150	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
B1L07_RS10165	COG0433	COG0433 Predicted ATPase
B1L07_RS10170	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
B1L07_RS10180	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
B1L07_RS10185	COG0412	Dienelactone hydrolase
B1L07_RS10195	COG0717	Belongs to the dCTP deaminase family
B1L07_RS10200	COG0489	protein tyrosine kinase activity
B1L07_RS10245	COG0697	spore germination
B1L07_RS10255	COG2311	Membrane
B1L07_RS10260	COG1047	Peptidyl-prolyl cis-trans
B1L07_RS10265	COG0791	NLP P60 protein
B1L07_RS10270	COG0791	NLP P60 protein
B1L07_RS10275	COG0612	Peptidase, M16
B1L07_RS10280	COG0612	Peptidase, M16
B1L07_RS10285	COG1301	dicarboxylic acid transport
B1L07_RS10305	COG1722	exodeoxyribonuclease VII activity
B1L07_RS10310	COG0142	geranyltranstransferase activity
B1L07_RS10320	COG0312	modulator of DNA gyrase
B1L07_RS10325	COG3028	Belongs to the UPF0307 family
B1L07_RS10355	COG2968	Membrane
B1L07_RS10365	COG4771	TonB-dependent receptor
B1L07_RS10375	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
B1L07_RS10385	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
B1L07_RS10400	COG0495	leucyl-tRNA aminoacylation
B1L07_RS10425	COG3118	belongs to the thioredoxin family
B1L07_RS10435	COG5001	Diguanylate cyclase
B1L07_RS10435	COG3706	GGDEF domain
B1L07_RS10435	COG4251	negative regulation of phosphorylation
B1L07_RS10435	COG2203	Gaf domain
B1L07_RS10460	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
B1L07_RS10465	COG0346	lactoylglutathione lyase activity
B1L07_RS10470	COG1131	(ABC) transporter
B1L07_RS10495	COG2878	Part of a membrane complex involved in electron transport
B1L07_RS10510	COG0116	Belongs to the methyltransferase superfamily
B1L07_RS10510	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
B1L07_RS10530	COG0494	nUDIX hydrolase
B1L07_RS10540	COG1024	Enoyl-CoA hydratase
B1L07_RS10550	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
B1L07_RS10560	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
B1L07_RS10565	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
B1L07_RS10570	COG0573	inorganic phosphate transmembrane transporter activity
B1L07_RS10575	COG0581	inorganic phosphate transmembrane transporter activity
B1L07_RS10585	COG0704	Plays a role in the regulation of phosphate uptake
B1L07_RS10590	COG1028	Short-chain dehydrogenase reductase Sdr
B1L07_RS10605	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
B1L07_RS10610	COG0557	exoribonuclease II activity
B1L07_RS10630	COG2814	Major facilitator Superfamily
B1L07_RS10680	COG0367	asparagine synthase
B1L07_RS10690	COG1393	Belongs to the ArsC family
B1L07_RS10700	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
B1L07_RS10705	COG0024	Methionine aminopeptidase
B1L07_RS10710	COG0052	Belongs to the universal ribosomal protein uS2 family
B1L07_RS10715	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
B1L07_RS10725	COG0528	UMP kinase activity
B1L07_RS10730	COG0233	cytoplasmic translational termination
B1L07_RS10740	COG0575	Belongs to the CDS family
B1L07_RS10745	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
B1L07_RS10750	COG0750	zinc metalloprotease
B1L07_RS10755	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
B1L07_RS10760	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
B1L07_RS10770	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
B1L07_RS10780	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
B1L07_RS10790	COG0825	malonyl-CoA metabolic process
B1L07_RS10795	COG1981	membrane
B1L07_RS10860	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
B1L07_RS10880	COG2202	Pas domain
B1L07_RS10880	COG2205	protein histidine kinase activity
B1L07_RS10905	COG1132	(ABC) transporter
B1L07_RS10915	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
B1L07_RS10940	COG1187	pseudouridine synthase activity
B1L07_RS10955	COG2501	S4 domain
B1L07_RS11025	COG0735	belongs to the Fur family
B1L07_RS11030	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
B1L07_RS11045	COG1024	Enoyl-CoA hydratase
B1L07_RS11045	COG1250	3-hydroxyacyl-CoA dehydrogenase
B1L07_RS11050	COG1946	Acyl-CoA thioesterase
B1L07_RS11070	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
B1L07_RS11080	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
B1L07_RS11120	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
B1L07_RS11135	COG2197	response regulator
B1L07_RS11140	COG4585	Histidine kinase
B1L07_RS11150	COG0850	regulation of cytokinetic process
B1L07_RS11160	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
B1L07_RS11170	COG2205	protein histidine kinase activity
B1L07_RS11180	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
B1L07_RS11215	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
B1L07_RS11245	COG2814	Major facilitator Superfamily
B1L07_RS11250	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
B1L07_RS11250	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
B1L07_RS11265	COG2207	Transcriptional regulator
B1L07_RS11265	COG1917	Cupin 2, conserved barrel domain protein
B1L07_RS11310	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
B1L07_RS11320	COG0330	HflC and HflK could
B1L07_RS11325	COG0330	HflC and HflK could
B1L07_RS11330	COG0604	alcohol dehydrogenase
B1L07_RS11350	COG0678	peroxiredoxin activity
B1L07_RS11360	COG4953	penicillin-binding protein 1C
B1L07_RS11365	COG2373	Large extracellular alpha-helical protein
B1L07_RS11395	COG0372	Belongs to the citrate synthase family
B1L07_RS11430	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
B1L07_RS11435	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
B1L07_RS11445	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
B1L07_RS11455	COG2814	Major facilitator Superfamily
B1L07_RS11460	COG5002	protein histidine kinase activity
B1L07_RS11460	COG0784	Response regulator, receiver
B1L07_RS11470	COG3038	cytochrome b561
B1L07_RS11490	COG1760	l-serine dehydratase
B1L07_RS11510	COG0527	aspartate kinase activity
B1L07_RS11510	COG0460	homoserine dehydrogenase
B1L07_RS11515	COG0626	cystathionine gamma-synthase activity
B1L07_RS11520	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
B1L07_RS11525	COG0739	heme binding
B1L07_RS11530	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
B1L07_RS11535	COG1272	protein, Hemolysin III
B1L07_RS11540	COG2982	Protein involved in outer membrane biogenesis
B1L07_RS11545	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
B1L07_RS11545	COG3620	sequence-specific DNA binding
B1L07_RS11545	COG0617	tRNA 3'-terminal CCA addition
B1L07_RS11550	COG0463	Glycosyl transferase, family 2
B1L07_RS11555	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
B1L07_RS11560	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
B1L07_RS11570	COG0457	Tetratricopeptide repeat
B1L07_RS11575	COG4206	TonB-dependent receptor
B1L07_RS11580	COG2226	methyltransferase
B1L07_RS11595	COG1960	acyl-CoA dehydrogenase activity
B1L07_RS11630	COG0404	The glycine cleavage system catalyzes the degradation of glycine
B1L07_RS11640	COG0330	HflC and HflK could
B1L07_RS11660	COG3956	TIGRFAM MazG family protein
B1L07_RS11665	COG1218	3'(2'),5'-bisphosphate nucleotidase
B1L07_RS11685	COG2201	protein-glutamate methylesterase activity
B1L07_RS11690	COG0643	Histidine kinase
B1L07_RS11690	COG2198	Histidine kinase
B1L07_RS11700	COG0840	transmembrane signaling receptor activity
B1L07_RS11705	COG0835	chemotaxis
B1L07_RS11720	COG0189	ligase activity
B1L07_RS11750	COG1764	response to oxidative stress
B1L07_RS11775	COG1959	2 iron, 2 sulfur cluster binding
B1L07_RS11780	COG0719	Fe-S assembly protein
B1L07_RS11790	COG0396	ATPase activity
B1L07_RS11795	COG0719	Fe-S assembly protein
B1L07_RS11800	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
B1L07_RS11810	COG2146	nitrite reductase [NAD(P)H] activity
B1L07_RS11815	COG4774	siderophore transport
B1L07_RS11825	COG3128	pkhd-type hydroxylase
B1L07_RS11835	COG4771	TonB-dependent receptor
B1L07_RS11855	COG1477	protein flavinylation
B1L07_RS11860	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
B1L07_RS11880	COG1028	Short-chain dehydrogenase reductase Sdr
B1L07_RS11910	COG0640	Transcriptional regulator
B1L07_RS11925	COG2205	protein histidine kinase activity
B1L07_RS11930	COG4771	TonB-dependent receptor
B1L07_RS11940	COG1555	photosystem II stabilization
B1L07_RS11960	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
B1L07_RS11970	COG0628	permease
B1L07_RS11980	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
B1L07_RS11995	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
B1L07_RS12010	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
B1L07_RS12015	COG0045	succinate-CoA ligase (ADP-forming) activity
B1L07_RS12040	COG3706	GGDEF domain
B1L07_RS12040	COG2203	Gaf domain
B1L07_RS12040	COG5001	Diguanylate cyclase
B1L07_RS12040	COG4251	negative regulation of phosphorylation
B1L07_RS12065	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
B1L07_RS12105	COG1459	type II secretion system
B1L07_RS12110	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
B1L07_RS12125	COG0745	RESPONSE REGULATOR receiver
B1L07_RS12135	COG0189	ligase activity
B1L07_RS12155	COG2022	thiamine diphosphate biosynthetic process
B1L07_RS12165	COG3273	potassium ion transport
B1L07_RS12165	COG0471	metal ion transport
B1L07_RS12180	COG0179	Fumarylacetoacetate (FAA) hydrolase
B1L07_RS12195	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
B1L07_RS12195	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
B1L07_RS12200	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
B1L07_RS12205	COG1115	amino acid carrier protein
B1L07_RS12215	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
B1L07_RS12220	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
B1L07_RS12230	COG0175	sulfate reduction
B1L07_RS12235	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
B1L07_RS12240	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
B1L07_RS12245	COG0175	sulfate reduction
B1L07_RS12275	COG1648	precorrin-2 dehydrogenase activity
B1L07_RS12275	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
B1L07_RS12285	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
B1L07_RS12290	COG3588	fructose-bisphosphate aldolase
B1L07_RS12295	COG0469	pyruvate kinase activity
B1L07_RS12305	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
B1L07_RS12320	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
B1L07_RS12325	COG3047	cAMP biosynthetic process
B1L07_RS12350	COG0427	acetyl-CoA hydrolase
B1L07_RS12365	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
B1L07_RS12370	COG1301	dicarboxylic acid transport
B1L07_RS12430	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
B1L07_RS12450	COG0254	rRNA binding
B1L07_RS12460	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
B1L07_RS12470	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
B1L07_RS12475	COG1758	RNA polymerase activity
B1L07_RS12490	COG1561	YicC-like family, N-terminal region
B1L07_RS12495	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
B1L07_RS12500	COG0346	lactoylglutathione lyase activity
B1L07_RS12510	COG0635	Involved in the biosynthesis of porphyrin-containing compound
B1L07_RS12535	COG3079	Belongs to the UPF0149 family
B1L07_RS12555	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
B1L07_RS12590	COG2912	Transglutaminase-like superfamily
B1L07_RS12610	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
B1L07_RS12625	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
B1L07_RS12630	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
B1L07_RS12635	COG1028	Short-chain dehydrogenase reductase Sdr
B1L07_RS12650	COG0671	phosphoesterase, PA-phosphatase related
B1L07_RS12660	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
B1L07_RS12665	COG0563	adenylate kinase activity
B1L07_RS12685	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
B1L07_RS12700	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
B1L07_RS12725	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
B1L07_RS12730	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
B1L07_RS12735	COG0405	Gamma-glutamyltransferase
B1L07_RS12785	COG3409	Peptidoglycan-binding domain 1 protein
B1L07_RS12785	COG3267	Type II secretory pathway component ExeA
B1L07_RS12790	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
B1L07_RS12825	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
B1L07_RS12845	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
B1L07_RS12860	COG0473	3-isopropylmalate dehydrogenase activity
B1L07_RS12865	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
B1L07_RS12895	COG3634	alkyl hydroperoxide reductase activity
B1L07_RS12900	COG0583	DNA-binding transcription factor activity
B1L07_RS12905	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
B1L07_RS12935	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
B1L07_RS12945	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
B1L07_RS12965	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
B1L07_RS12970	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
B1L07_RS12985	COG2096	Adenosyltransferase
B1L07_RS12995	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
B1L07_RS13000	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
B1L07_RS13005	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
B1L07_RS13010	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
B1L07_RS13015	COG2967	ApaG domain
B1L07_RS13020	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
B1L07_RS13040	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
B1L07_RS13060	COG0861	Integral membrane protein TerC family
B1L07_RS13065	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
B1L07_RS13070	COG0642	Histidine kinase
B1L07_RS13090	COG4771	TonB-dependent receptor
B1L07_RS13100	COG0667	Aldo Keto reductase
B1L07_RS13105	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
B1L07_RS13115	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
B1L07_RS13140	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
B1L07_RS13160	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
B1L07_RS13165	COG1607	acyl-coa hydrolase
B1L07_RS13190	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
B1L07_RS13200	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
B1L07_RS13225	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
B1L07_RS13235	COG0494	nUDIX hydrolase
B1L07_RS13245	COG0739	heme binding
B1L07_RS13260	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
B1L07_RS13270	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
B1L07_RS13295	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
B1L07_RS13310	COG3116	cell division
B1L07_RS13315	COG0275	rRNA processing
B1L07_RS13320	COG2001	Belongs to the MraZ family
B1L07_RS13350	COG1988	membrane-bound metal-dependent
B1L07_RS13355	COG0277	FAD linked oxidase domain protein
B1L07_RS13365	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
B1L07_RS13370	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
B1L07_RS13385	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
B1L07_RS13385	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
B1L07_RS13395	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
B1L07_RS13405	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
B1L07_RS13415	COG0488	(ABC) transporter
B1L07_RS13420	COG2252	PERMEase
B1L07_RS13430	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
B1L07_RS13435	COG0457	Tetratricopeptide repeat
B1L07_RS13435	COG3118	belongs to the thioredoxin family
B1L07_RS13440	COG1215	transferase activity, transferring glycosyl groups
B1L07_RS13445	COG1215	transferase activity, transferring glycosyl groups
B1L07_RS13460	COG2194	sulfuric ester hydrolase activity
B1L07_RS13480	COG0457	Tetratricopeptide repeat
B1L07_RS13485	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
B1L07_RS13490	COG1215	transferase activity, transferring glycosyl groups
B1L07_RS13495	COG1215	transferase activity, transferring glycosyl groups
B1L07_RS13530	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
B1L07_RS13535	COG4974	Belongs to the 'phage' integrase family
B1L07_RS13545	COG0795	lipopolysaccharide-transporting ATPase activity
B1L07_RS13555	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
B1L07_RS13570	COG0525	valine-tRNA ligase activity
B1L07_RS13580	COG0456	acetyltransferase
B1L07_RS13590	COG1183	phosphatidylcholine synthase activity
B1L07_RS13600	COG0442	prolyl-tRNA aminoacylation
B1L07_RS13615	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
B1L07_RS13625	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
B1L07_RS13625	COG3218	ABC-type transport auxiliary lipoprotein component
B1L07_RS13640	COG0024	Methionine aminopeptidase
B1L07_RS13665	COG3214	Protein conserved in bacteria
B1L07_RS13735	COG3550	peptidyl-serine autophosphorylation
B1L07_RS13790	COG2375	cellular response to nickel ion
B1L07_RS13835	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
B1L07_RS13870	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
B1L07_RS13880	COG0459	protein refolding
B1L07_RS13885	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
B1L07_RS13900	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
B1L07_RS13905	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
B1L07_RS13910	COG0511	ligase activity, forming carbon-carbon bonds
B1L07_RS13915	COG0439	Biotin carboxylase
B1L07_RS13920	COG2264	protein methyltransferase activity
B1L07_RS13930	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
B1L07_RS13935	COG0138	bifunctional purine biosynthesis protein purh
B1L07_RS13955	COG0667	Aldo Keto reductase
B1L07_RS13965	COG1289	transmembrane transporter activity
B1L07_RS14070	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
B1L07_RS14075	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
B1L07_RS14090	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
B1L07_RS14095	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
B1L07_RS14100	COG0730	response to heat
B1L07_RS14110	COG0134	indole-3-glycerol-phosphate synthase activity
B1L07_RS14115	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
B1L07_RS14125	COG0512	Glutamine amidotransferase of anthranilate synthase
B1L07_RS14140	COG2205	protein histidine kinase activity
B1L07_RS14160	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
B1L07_RS14165	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
B1L07_RS14170	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
B1L07_RS14190	COG1006	Multisubunit Na H antiporter MnhC subunit
B1L07_RS14195	COG0651	ATP synthesis coupled electron transport
B1L07_RS14205	COG2212	antiporter activity
B1L07_RS14210	COG1320	monovalent cation:proton antiporter activity
B1L07_RS14250	COG3104	oligopeptide transport
B1L07_RS14255	COG3483	tryptophan 2,3-dioxygenase activity
B1L07_RS14260	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
B1L07_RS14275	COG0508	dehydrogenase complex catalyzes the overall conversion of
B1L07_RS14300	COG0702	epimerase
B1L07_RS14310	COG0612	Peptidase, M16
B1L07_RS14330	COG2354	Protein conserved in bacteria
B1L07_RS14340	COG1368	sulfuric ester hydrolase activity
B1L07_RS14345	COG3264	Mechanosensitive ion channel
B1L07_RS14345	COG1196	nuclear chromosome segregation
B1L07_RS14360	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
B1L07_RS14375	COG4807	Protein conserved in bacteria
B1L07_RS14385	COG0789	Transcriptional regulator
B1L07_RS14420	COG2318	DinB family
B1L07_RS14435	COG0596	Alpha beta hydrolase
B1L07_RS14465	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
B1L07_RS14485	COG0628	permease
B1L07_RS14500	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
B1L07_RS14515	COG2197	response regulator
B1L07_RS14520	COG4585	Histidine kinase
B1L07_RS14525	COG0842	Transport permease protein
B1L07_RS14530	COG1131	(ABC) transporter
B1L07_RS14535	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
B1L07_RS14540	COG1136	(ABC) transporter
B1L07_RS14565	COG2962	Rard protein
B1L07_RS14570	COG0697	spore germination
B1L07_RS14590	COG0180	Tryptophanyl-tRNA synthetase
B1L07_RS14600	COG3237	CsbD-like
B1L07_RS14670	COG3038	cytochrome b561
B1L07_RS14680	COG5001	Diguanylate cyclase
B1L07_RS14680	COG3300	MHYT domain
B1L07_RS14690	COG3655	Transcriptional regulator
B1L07_RS14695	COG1506	peptidase
B1L07_RS14700	COG2205	protein histidine kinase activity
B1L07_RS14700	COG0784	Response regulator, receiver
B1L07_RS14710	COG0784	Response regulator, receiver
B1L07_RS14710	COG2205	protein histidine kinase activity
B1L07_RS14735	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
B1L07_RS14740	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
B1L07_RS14740	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
B1L07_RS14745	COG3228	Belongs to the MtfA family
B1L07_RS14820	COG1285	pathogenesis
B1L07_RS14825	COG1335	isochorismatase
B1L07_RS14835	COG1902	pentaerythritol trinitrate reductase activity
B1L07_RS14850	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
B1L07_RS14875	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
B1L07_RS14885	COG0697	spore germination
B1L07_RS14910	COG1960	acyl-CoA dehydrogenase activity
B1L07_RS14950	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
B1L07_RS14955	COG0583	DNA-binding transcription factor activity
B1L07_RS14965	COG0277	FAD linked oxidase domain protein
B1L07_RS14970	COG1304	FMN binding
B1L07_RS14975	COG2186	Transcriptional regulator
B1L07_RS14980	COG0681	Belongs to the peptidase S26 family
B1L07_RS14995	COG0339	signal peptide processing
B1L07_RS15000	COG0415	Belongs to the DNA photolyase family
B1L07_RS15050	COG0564	pseudouridine synthase activity
B1L07_RS15070	COG1181	Belongs to the D-alanine--D-alanine ligase family
B1L07_RS15085	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
B1L07_RS15090	COG0318	PFAM AMP-dependent synthetase and ligase
B1L07_RS15100	COG0596	Alpha beta hydrolase
B1L07_RS15110	COG1573	uracil-dna glycosylase
B1L07_RS15120	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
B1L07_RS15130	COG0612	Peptidase, M16
B1L07_RS15140	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
B1L07_RS15150	COG1804	L-carnitine dehydratase bile acid-inducible protein F
B1L07_RS15175	COG1199	ATP-dependent helicase activity
B1L07_RS15185	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
B1L07_RS15205	COG3781	membrane
B1L07_RS15245	COG3209	COG3209 Rhs family protein
B1L07_RS15250	COG0625	glutathione transferase activity
B1L07_RS15265	COG1668	transmembrane transport
B1L07_RS15275	COG2267	carboxylic ester hydrolase activity
B1L07_RS15300	COG1131	(ABC) transporter
B1L07_RS15305	COG0842	Transport permease protein
B1L07_RS15310	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
B1L07_RS15320	COG0084	hydrolase, TatD family'
B1L07_RS15325	COG1643	Atp-dependent helicase
B1L07_RS15335	COG1187	pseudouridine synthase activity
B1L07_RS15345	COG0667	Aldo Keto reductase
B1L07_RS15365	COG2239	Acts as a magnesium transporter
B1L07_RS15385	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
B1L07_RS15395	COG0463	Glycosyl transferase, family 2
B1L07_RS15400	COG1028	Short-chain dehydrogenase reductase Sdr
B1L07_RS15425	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
B1L07_RS15440	COG0251	oxidation-reduction process
B1L07_RS15465	COG0408	coproporphyrinogen oxidase activity
B1L07_RS15470	COG2323	membrane
B1L07_RS15475	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
B1L07_RS15475	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
B1L07_RS15490	COG0210	DNA helicase
B1L07_RS15505	COG0227	Belongs to the bacterial ribosomal protein bL28 family
B1L07_RS15550	COG0463	Glycosyl transferase, family 2
B1L07_RS15570	COG1192	Involved in chromosome partitioning
B1L07_RS15580	COG0357	Ribosomal RNA small subunit methyltransferase G
B1L07_RS15605	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
B1L07_RS15610	COG0583	DNA-binding transcription factor activity
B1L07_RS15625	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
B1L07_RS15630	COG1262	PFAM Formylglycine-generating sulfatase enzyme
B1L07_RS15640	COG1804	L-carnitine dehydratase bile acid-inducible protein F
B1L07_RS15650	COG0671	phosphoesterase, PA-phosphatase related
B1L07_RS15680	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
B1L07_RS15700	COG3938	Belongs to the proline racemase family
B1L07_RS15720	COG3162	membrane
B1L07_RS15740	COG0840	transmembrane signaling receptor activity
B1L07_RS15745	COG1971	Probably functions as a manganese efflux pump
B1L07_RS15750	COG2205	protein histidine kinase activity
B1L07_RS15755	COG0784	Response regulator, receiver
B1L07_RS15755	COG4191	Histidine kinase
B1L07_RS15805	COG3209	COG3209 Rhs family protein
B1L07_RS15830	COG0729	surface antigen
B1L07_RS15835	COG4771	TonB-dependent receptor
B1L07_RS15840	COG0457	Tetratricopeptide repeat
B1L07_RS15850	COG0752	glycyl-tRNA synthetase alpha subunit
B1L07_RS15855	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
B1L07_RS15860	COG0518	GMP synthase (glutamine-hydrolyzing) activity
B1L07_RS15860	COG0519	Catalyzes the synthesis of GMP from XMP
B1L07_RS15875	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
B1L07_RS15885	COG2198	Histidine kinase
B1L07_RS15885	COG0784	Response regulator, receiver
B1L07_RS15885	COG2205	protein histidine kinase activity
B1L07_RS15910	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
B1L07_RS15915	COG2267	carboxylic ester hydrolase activity
B1L07_RS15925	COG2974	May be involved in recombination
B1L07_RS15930	COG0037	tRNA processing
B1L07_RS15955	COG2937	Belongs to the GPAT DAPAT family
B1L07_RS15965	COG0284	orotidine-5'-phosphate decarboxylase activity
B1L07_RS15970	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
B1L07_RS15975	COG3132	Protein of unknown function, DUF480
B1L07_RS15990	COG0210	DNA helicase
B1L07_RS16005	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
B1L07_RS16010	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
B1L07_RS16050	COG1752	Esterase of the alpha-beta hydrolase superfamily
B1L07_RS16065	COG3186	Phenylalanine-4-hydroxylase
B1L07_RS16125	COG1741	Belongs to the pirin family
B1L07_RS16130	COG0583	DNA-binding transcription factor activity
B1L07_RS16150	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
B1L07_RS16155	COG1074	ATP-dependent DNA helicase activity
B1L07_RS16170	COG1127	ABC transporter
B1L07_RS16175	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
B1L07_RS16205	COG0386	Belongs to the glutathione peroxidase family
B1L07_RS16235	COG0531	amino acid
B1L07_RS16245	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
B1L07_RS16250	COG0861	Integral membrane protein TerC family
B1L07_RS16260	COG0584	glycerophosphoryl diester phosphodiesterase
B1L07_RS16265	COG0488	(ABC) transporter
B1L07_RS16280	COG0706	membrane insertase activity
B1L07_RS16290	COG0230	Belongs to the bacterial ribosomal protein bL34 family