locus-tag	class	description
F0P95_RS00125	ENOG4105TNG	K13735 adhesin invasin
F0P95_RS00290	ENOG4108DT4	serine threonine protein kinase
F0P95_RS00305	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
F0P95_RS00315	ENOG41080E2	ribosomal-protein-alanine acetyltransferase
F0P95_RS00330	ENOG4105SYT	Methylenetetrahydrofolate reductase
F0P95_RS00340	ENOG4105M6F	mutator MutT protein
F0P95_RS00345	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
F0P95_RS00350	ENOG4105DR5	peptidase
F0P95_RS00360	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
F0P95_RS00365	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
F0P95_RS00370	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
F0P95_RS00375	ENOG4105K7E	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity)
F0P95_RS00385	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
F0P95_RS00400	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
F0P95_RS00405	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
F0P95_RS00410	ENOG4105CJN	penicillin-binding protein
F0P95_RS00415	ENOG4106932	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
F0P95_RS00420	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
F0P95_RS00425	ENOG4108V6E	Cell division protein mraZ
F0P95_RS00450	ENOG41082RQ	UPF0102 protein
F0P95_RS00455	ENOG4105S2T	inner membrane protein YbcI
F0P95_RS00460	ENOG4105CQB	FAD linked oxidase domain protein
F0P95_RS00465	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
F0P95_RS00470	ENOG4107YIM	Involved in the transcription termination process (By similarity)
F0P95_RS00475	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
F0P95_RS00480	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
F0P95_RS00490	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
F0P95_RS00500	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
F0P95_RS00505	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
F0P95_RS00515	ENOG4105C5H	ABC transporter
F0P95_RS00520	ENOG4105C7N	Xanthine uracil vitamin C permease
F0P95_RS00530	ENOG4105K2Z	endo-1,4-d-glucanase (EC 3.2.1.4)
F0P95_RS00535	ENOG4105EJG	cellulose synthase
F0P95_RS00540	ENOG4107EEX	Cellulose synthase regulator protein
F0P95_RS00545	ENOG4107QZ7	Cellulose synthase catalytic subunit
F0P95_RS00560	ENOG4105D1V	cellulose synthase operon protein YhjU
F0P95_RS00575	ENOG4107RH7	Nicotinate phosphoribosyltransferase
F0P95_RS00580	ENOG4105EJG	cellulose synthase
F0P95_RS00585	ENOG4105K2Z	endo-1,4-d-glucanase (EC 3.2.1.4)
F0P95_RS00590	ENOG4107EEX	Cellulose synthase regulator protein
F0P95_RS00595	ENOG4107QZ7	Cellulose synthase catalytic subunit
F0P95_RS00620	ENOG4107QIK	phosphoribosylformylglycinamidine synthase
F0P95_RS00630	ENOG4105T95	Thiol disulfide interChange protein
F0P95_RS00635	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
F0P95_RS00645	ENOG4108K5H	permease YjgP YjgQ family protein
F0P95_RS00655	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
F0P95_RS00670	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
F0P95_RS00680	ENOG4105KEG	ribosomal-protein-alanine acetyltransferase
F0P95_RS00690	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
F0P95_RS00700	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
F0P95_RS00705	ENOG4105VFQ	Histone family protein nucleoid-structuring protein H-NS
F0P95_RS00720	ENOG4105DHJ	ABC, transporter
F0P95_RS00725	ENOG4108SNX	Mammalian cell entry related domain protein
F0P95_RS00740	ENOG4106A4F	Removes the N-terminal methionine from nascent proteins (By similarity)
F0P95_RS00750	ENOG4107S1E	Beta-lactamase
F0P95_RS00755	ENOG4105T0Z	Conserved Protein
F0P95_RS00785	ENOG4107RNH	Outer membrane receptor FepA
F0P95_RS00865	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
F0P95_RS00875	ENOG4105Q26	Siderophore-interacting protein
F0P95_RS00920	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
F0P95_RS00935	ENOG4105KWI	UPF0339 protein
F0P95_RS00940	ENOG41082IR	Excinuclease ABC C subunit domain protein
F0P95_RS00950	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
F0P95_RS00960	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
F0P95_RS00965	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
F0P95_RS00970	ENOG4105VF7	tolerance protein
F0P95_RS00975	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
F0P95_RS00980	ENOG4107QX9	Thiol disulfide interChange protein
F0P95_RS00985	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
F0P95_RS00990	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
F0P95_RS00995	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
F0P95_RS01000	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
F0P95_RS01010	ENOG4105VY0	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity)
F0P95_RS01015	ENOG4105DC1	bifunctional purine biosynthesis protein purh
F0P95_RS01030	ENOG4105C12	Phosphoribosylglycinamide synthetase
F0P95_RS01035	ENOG4105CPC	Aldo Keto reductase
F0P95_RS01040	ENOG4105EQ2	LysR family Transcriptional regulator
F0P95_RS01055	ENOG4105C5Q	Transcriptional regulator
F0P95_RS01060	ENOG4108J8Q	Catalyzes the facilitated diffusion of 2-acyl-glycero-3- phosphoethanolamine (2-acyl-GPE) into the cell (By similarity)
F0P95_RS01080	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
F0P95_RS01115	ENOG4105BZU	Histidine kinase
F0P95_RS01120	ENOG4108UQY	Iron-storage protein
F0P95_RS01130	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
F0P95_RS01150	ENOG4108UJD	30S ribosomal protein S9
F0P95_RS01155	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
F0P95_RS01160	ENOG4108S0N	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol (By similarity)
F0P95_RS01170	ENOG4105FDS	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity)
F0P95_RS01175	ENOG4107RYR	Transcriptional regulator, Crp Fnr family
F0P95_RS01180	ENOG410635A	Membrane
F0P95_RS01190	ENOG4105DK0	Indole-3-glycerol phosphate synthase
F0P95_RS01195	ENOG4108I0Q	anthranilate phosphoribosyltransferase
F0P95_RS01205	ENOG4105DDQ	anthranilate synthase
F0P95_RS01250	ENOG41080IJ	Diacylglycerol kinase
F0P95_RS01285	ENOG4105E3B	Multicopper oxidase
F0P95_RS01315	ENOG4105WKS	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
F0P95_RS01340	ENOG4108IJF	Heavy metal efflux pump, CzcA
F0P95_RS01345	ENOG4105W1Y	Transcriptional regulator
F0P95_RS01365	ENOG4105CY0	Metallo-Beta-Lactamase
F0P95_RS01370	ENOG4105CMW	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity)
F0P95_RS01385	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
F0P95_RS01395	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
F0P95_RS01405	ENOG4105DFP	Integrase
F0P95_RS01415	ENOG4105CRQ	synthase (Component I)
F0P95_RS01445	ENOG4105DJV	ribulose-phosphate 3-epimerase
F0P95_RS01450	ENOG41066UG	Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity)
F0P95_RS01455	ENOG4105C8V	SAICAR synthetase
F0P95_RS01470	ENOG4105D65	subunit l
F0P95_RS01475	ENOG4108ZE9	Monovalent cation H antiporter subunit C
F0P95_RS01480	ENOG4107R4Z	monovalent cation h antiporter subunit d
F0P95_RS01490	ENOG4105W4C	monovalent cation H antiporter subunit F
F0P95_RS01495	ENOG4105KJM	monovalent cation h antiporter subunit g
F0P95_RS01505	ENOG4105F1J	Homogentisate 1,2-dioxygenase
F0P95_RS01510	ENOG4105E6K	4-Hydroxyphenylpyruvate dioxygenase
F0P95_RS01530	ENOG4105DUX	Transporter
F0P95_RS01535	ENOG4105HJ8	Catalyzes the oxidative cleavage of the L-tryptophan (L- Trp) pyrrole ring (By similarity)
F0P95_RS01540	ENOG4107RUY	(E1 component), alpha subunit
F0P95_RS01545	ENOG4105CPP	Dehydrogenase, E1 component
F0P95_RS01555	ENOG4105C7S	Dehydrogenase
F0P95_RS01580	ENOG4105K4T	epimerase
F0P95_RS01585	ENOG4105BZU	Histidine kinase
F0P95_RS01595	ENOG4108JJA	ABC, transporter
F0P95_RS01610	ENOG4108MBX	Secretion Protein
F0P95_RS01625	ENOG4105CKW	Inner membrane protein yedI
F0P95_RS01630	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
F0P95_RS01635	ENOG4107RES	phosphoglycerol transferase I
F0P95_RS01640	ENOG4105EGS	Mechanosensitive ion channel
F0P95_RS01655	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
F0P95_RS01670	ENOG4108W15	Protein of unknown function (DUF1456)
F0P95_RS01730	ENOG4107SKW	Inherit from COG: Alpha beta hydrolase
F0P95_RS01760	ENOG4105C0H	protease
F0P95_RS01780	ENOG4105DSF	transport protein
F0P95_RS01790	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
F0P95_RS01795	ENOG4107VGR	Catalase
F0P95_RS01805	ENOG4108S01	response regulator
F0P95_RS01810	ENOG4105BZU	Histidine kinase
F0P95_RS01815	ENOG4105KCT	ABC transporter
F0P95_RS01820	ENOG4108M15	ABC transporter
F0P95_RS01825	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
F0P95_RS01830	ENOG4105C19	ABC transporter
F0P95_RS01840	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
F0P95_RS01845	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
F0P95_RS01855	ENOG4105FR1	rard protein
F0P95_RS01860	ENOG4105FDR	Membrane
F0P95_RS01880	ENOG4105C31	Tryptophanyl-tRNA synthetase
F0P95_RS01890	ENOG4105VDW	Csbd family
F0P95_RS01910	ENOG4105D4P	Coproporphyrinogen iii oxidase
F0P95_RS01915	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
F0P95_RS01920	ENOG4105DSQ	Nitric oxide reductase
F0P95_RS01960	ENOG4105CPW	cytochrome b561
F0P95_RS01975	ENOG4108ESX	Receptor
F0P95_RS01990	ENOG4105VMP	Transcriptional regulator
F0P95_RS02000	ENOG4105BZU	Histidine kinase
F0P95_RS02005	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
F0P95_RS02010	ENOG4105BZU	Histidine kinase
F0P95_RS02015	ENOG41068CG	regulatoR
F0P95_RS02020	ENOG4106AS2	Outer membrane autotransporter
F0P95_RS02050	ENOG4108194	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
F0P95_RS02055	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
F0P95_RS02070	ENOG4105EB3	Histidine kinase
F0P95_RS02075	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
F0P95_RS02085	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
F0P95_RS02090	ENOG410814C	multidrug resistance protein
F0P95_RS02095	ENOG4105DSS	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
F0P95_RS02140	ENOG4105KT7	mgtC SapB transporter
F0P95_RS02145	ENOG4108RWI	nicotinamidase
F0P95_RS02155	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
F0P95_RS02160	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
F0P95_RS02170	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
F0P95_RS02175	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
F0P95_RS02190	ENOG4105D6Z	AFG1 family ATPase
F0P95_RS02200	ENOG4108TZV	Membrane
F0P95_RS02225	ENOG4105C1G	acyl-Coa dehydrogenase
F0P95_RS02230	ENOG4107QX3	carboxylase
F0P95_RS02255	ENOG4105BZU	Histidine kinase
F0P95_RS02260	ENOG4108I9X	Isocitrate lyase
F0P95_RS02265	ENOG4107QP3	malate synthase g
F0P95_RS02270	ENOG4107R11	Transcriptional regulator
F0P95_RS02280	ENOG4105CXG	d-lactate dehydrogenase
F0P95_RS02285	ENOG4105DMF	Dehydrogenase
F0P95_RS02290	ENOG41073TP	transcriptional regulator
F0P95_RS02295	ENOG4105DAA	L-lactate
F0P95_RS02300	ENOG4105DY9	regulatoR
F0P95_RS02315	ENOG4105C3F	Signal peptidase i
F0P95_RS02330	ENOG4105DGW	oligopeptidase A
F0P95_RS02335	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
F0P95_RS02345	ENOG4108YZN	class I peptide chain release factor
F0P95_RS02365	ENOG4107QJZ	Glycosyl transferase, family 2
F0P95_RS02395	ENOG4105DR9	pseudouridine synthase
F0P95_RS02405	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
F0P95_RS02415	ENOG4105CPF	Cell wall formation (By similarity)
F0P95_RS02430	ENOG4107VBM	3-beta hydroxysteroid dehydrogenase isomerase
F0P95_RS02435	ENOG410680H	amp-dependent synthetase and ligase
F0P95_RS02445	ENOG4108J2P	Alpha beta hydrolase fold
F0P95_RS02450	ENOG4108RG0	uracil-dna glycosylase
F0P95_RS02455	ENOG4106RHG	Yeca family
F0P95_RS02460	ENOG4105E2T	synthase III
F0P95_RS02480	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
F0P95_RS02490	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
F0P95_RS02495	ENOG4105C1G	acyl-Coa dehydrogenase
F0P95_RS02500	ENOG4105C85	amino acid
F0P95_RS02515	ENOG4105DVT	helicase
F0P95_RS02525	ENOG4105E2X	shikimate dehydrogenase
F0P95_RS02540	ENOG4105D52	delta-aminolevulinic acid dehydratase
F0P95_RS02545	ENOG4105FFC	UPF0187 protein
F0P95_RS02580	ENOG4105CYM	Glutathione S-transferase
F0P95_RS02595	ENOG4108SDH	ABC, transporter
F0P95_RS02600	ENOG4108IUW	ABC transporter
F0P95_RS02635	ENOG4105DA5	(ABC) transporter
F0P95_RS02640	ENOG4105E3A	(ABC) transporter
F0P95_RS02645	ENOG41063V1	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
F0P95_RS02660	ENOG4105F8V	Hydrolase, tatD family
F0P95_RS02665	ENOG4105CQ7	ATP-dependent helicase
F0P95_RS02675	ENOG4108R99	pseudouridine synthase
F0P95_RS02685	ENOG4105CPC	Aldo Keto reductase
F0P95_RS02690	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
F0P95_RS02695	ENOG4105CD5	CoA-binding domain protein
F0P95_RS02705	ENOG4105CJW	magnesium transporter
F0P95_RS02710	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
F0P95_RS02725	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
F0P95_RS02735	ENOG4106N3V	dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83)
F0P95_RS02740	ENOG4105C2D	reductase
F0P95_RS02745	ENOG4105M2Z	protein tyrosine serine phosphatase
F0P95_RS02750	ENOG4107ZSV	Receptor
F0P95_RS02780	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
F0P95_RS02820	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
F0P95_RS02825	ENOG4107VMU	Membrane
F0P95_RS02830	ENOG4105C2M	dna polymerase I
F0P95_RS02845	ENOG4105C4R	Atp-dependent dna helicase
F0P95_RS02855	ENOG4105W0E	50S ribosomal protein L33
F0P95_RS02860	ENOG4105KDC	50s ribosomal protein l28
F0P95_RS02905	ENOG4105CKK	Glycosyl transferase, family 2
F0P95_RS02920	ENOG4105FA0	parb-like partition protein
F0P95_RS02925	ENOG4107QJE	Chromosome Partitioning Protein
F0P95_RS02930	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
F0P95_RS02950	ENOG4105CGB	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity)
F0P95_RS02955	ENOG4105E0C	molybdate abc transporter
F0P95_RS02960	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
F0P95_RS02970	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
F0P95_RS02975	ENOG41076YT	nitrate reductase, gamma subunit
F0P95_RS02980	ENOG4105R3A	Nitrate reductase
F0P95_RS02985	ENOG4108IUE	nitrate reductase beta subunit
F0P95_RS02990	ENOG4105CRU	nitrate reductase, alpha subunit
F0P95_RS02995	ENOG4105DQQ	Major facilitator superfamily MFS_1
F0P95_RS03005	ENOG41085AN	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
F0P95_RS03010	ENOG4108ZAF	Molybdopterin
F0P95_RS03020	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
F0P95_RS03025	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
F0P95_RS03030	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
F0P95_RS03045	ENOG4105F4R	Transcriptional regulator mode
F0P95_RS03050	ENOG4105D05	Receptor
F0P95_RS03060	ENOG4105S10	periplasmic binding protein
F0P95_RS03065	ENOG4108I9K	permease protein
F0P95_RS03070	ENOG4105E0A	ABC, transporter
F0P95_RS03075	ENOG4107R9T	Catalyzes the formation of 5-methyl-uridine at position 54 (m5U54) in all tRNAs (By similarity)
F0P95_RS03085	ENOG41062QD	Membrane
F0P95_RS03095	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
F0P95_RS03105	ENOG4105C8Q	Methyl-accepting chemotaxis
F0P95_RS03110	ENOG4108UI1	Probably functions as a manganese efflux pump (By similarity)
F0P95_RS03115	ENOG4105BZU	Histidine kinase
F0P95_RS03120	ENOG4105CQZ	Histidine kinase
F0P95_RS03125	ENOG4105BZU	Histidine kinase
F0P95_RS03145	ENOG4105ETX	regulatoR
F0P95_RS03170	ENOG4105CFU	surface antigen
F0P95_RS03175	ENOG4105D05	Receptor
F0P95_RS03180	ENOG4107RDJ	Sulfotransferase
F0P95_RS03185	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
F0P95_RS03190	ENOG4108HMW	glycyl-tRNA synthetase, alpha subunit
F0P95_RS03195	ENOG4107QHF	type ii secretion system protein e
F0P95_RS03200	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
F0P95_RS03210	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
F0P95_RS03215	ENOG4105X8U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
F0P95_RS03230	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
F0P95_RS03235	ENOG4105D74	hydrolase
F0P95_RS03245	ENOG4105DH7	May be involved in recombination (By similarity)
F0P95_RS03250	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
F0P95_RS03275	ENOG4105E55	glycerol-3-phosphate acyltransferase
F0P95_RS03285	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
F0P95_RS03290	ENOG4105CUR	5'-nucleotidase, lipoprotein e(p4) family
F0P95_RS03295	ENOG4108YXG	UPF0502 protein
F0P95_RS03305	ENOG4105C4R	Atp-dependent dna helicase
F0P95_RS03310	ENOG4107104	thymidine kinase
F0P95_RS03320	ENOG4105DJ9	glucan biosynthesis protein
F0P95_RS03325	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
F0P95_RS03360	ENOG4105D78	K07001 NTE family protein
F0P95_RS03380	ENOG4105CTK	cobaltochelatase, cobn subunit
F0P95_RS03385	ENOG4105D05	Receptor
F0P95_RS03395	ENOG4105MIR	Phenylalanine 4-monooxygenase
F0P95_RS03455	ENOG4105C2I	pirin domain protein
F0P95_RS03460	ENOG4105HEI	LysR family (Transcriptional regulator
F0P95_RS03475	ENOG4107QKA	exodeoxyribonuclease V beta
F0P95_RS03480	ENOG4105DSY	exodeoxyribonuclease V, gamma
F0P95_RS03485	ENOG4105DHJ	ABC, transporter
F0P95_RS03490	ENOG4105CY3	ABC transporter, permease
F0P95_RS03495	ENOG4107PE3	Mammalian cell entry related domain protein
F0P95_RS03510	ENOG410903C	(LipO)protein
F0P95_RS03520	ENOG4108V06	Glutathione peroxidase
F0P95_RS03530	ENOG4105CGY	Dna recombination protein
F0P95_RS03535	ENOG4108NIW	Leucine export protein LeuE
F0P95_RS03545	ENOG4105CUB	amino acid
F0P95_RS03555	ENOG4105DR4	Methyltransferase
F0P95_RS03560	ENOG4105DU1	integral membrane protein, terc
F0P95_RS03570	ENOG4106MZZ	glycerophosphoryl diester phosphodiesterase
F0P95_RS03605	ENOG41082EK	Restriction modification system DNA (Specificity
F0P95_RS03620	ENOG4105DFP	Integrase
F0P95_RS03635	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
F0P95_RS03640	ENOG41067YR	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
F0P95_RS03645	ENOG4105VG0	50S ribosomal protein l34
F0P95_RS03650	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
F0P95_RS03655	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
F0P95_RS03660	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
F0P95_RS03665	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
F0P95_RS03675	ENOG4108K0D	peptidase, M48
F0P95_RS03705	ENOG4108BUD	transposase
F0P95_RS03740	ENOG4108BUD	transposase
F0P95_RS03775	ENOG4108BUD	transposase
F0P95_RS03790	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
F0P95_RS03800	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
F0P95_RS03810	ENOG4105CGF	Aromatic amino acid aminotransferase
F0P95_RS03815	ENOG4105CHB	tonB-dependent Receptor
F0P95_RS03825	ENOG4108UHU	Aldolase
F0P95_RS03830	ENOG4105D7K	pfkb domain protein
F0P95_RS03835	ENOG4105D05	Receptor
F0P95_RS03850	ENOG4105EBR	Carboxylesterase
F0P95_RS03865	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
F0P95_RS03875	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
F0P95_RS03880	ENOG4105ETE	Transcriptional regulator (LacI family
F0P95_RS03885	ENOG4105CHR	reductase
F0P95_RS03895	ENOG4105EUJ	GTP cyclohydrolase i
F0P95_RS03915	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
F0P95_RS03935	ENOG4105E46	N-alpha,N-alpha,N-alpha-trimethyl-L-histidine metabolic process
F0P95_RS03940	ENOG41067HS	methyltransferase
F0P95_RS03945	ENOG4105DSB	aldose 1-epimerase
F0P95_RS03950	ENOG4105DKK	Benzoate
F0P95_RS03985	ENOG4108Z5K	methylglyoxal synthase
F0P95_RS03990	ENOG4105BZ8	glutamate synthase
F0P95_RS03995	ENOG4105CBC	glutamate synthase
F0P95_RS04030	ENOG4108I5C	dEAD DEAH box helicase
F0P95_RS04060	ENOG4105EBA	Specifically methylates the adenine in position 1618 of 23S rRNA (By similarity)
F0P95_RS04070	ENOG4105F37	PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX. PSI is a plastocyanin cytochrome c6-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn. Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin or cytochrome c6
F0P95_RS04100	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
F0P95_RS04160	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
F0P95_RS04170	ENOG4105M4E	phosphohistidine phosphatase, SixA
F0P95_RS04180	ENOG4107RZC	phospholipase d
F0P95_RS04190	ENOG4105KA0	thioesterase Superfamily protein
F0P95_RS04195	ENOG4105BZU	Histidine kinase
F0P95_RS04225	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
F0P95_RS04230	ENOG4105C5F	glutamine synthetase
F0P95_RS04235	ENOG4108YZA	Nitrogen regulatory protein pii
F0P95_RS04240	ENOG4105BZU	Histidine kinase
F0P95_RS04245	ENOG4105CUX	Signal transduction histidine kinase
F0P95_RS04250	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
F0P95_RS04255	ENOG4105D9P	serine threonine protein kinase
F0P95_RS04260	ENOG4108Z7T	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
F0P95_RS04265	ENOG4108Z7T	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
F0P95_RS04275	ENOG4105CHU	acetyl-coa acetyltransferase
F0P95_RS04325	ENOG4105M78	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity)
F0P95_RS04330	ENOG4105IX2	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity)
F0P95_RS04335	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
F0P95_RS04345	ENOG4107ZQV	short-chain dehydrogenase reductase
F0P95_RS04350	ENOG4105VFQ	Histone family protein nucleoid-structuring protein H-NS
F0P95_RS04370	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
F0P95_RS04380	ENOG4108HF7	Gcn5-related n-acetyltransferase
F0P95_RS04385	ENOG4105KWG	Pfam:DUF1696
F0P95_RS04400	ENOG4105KNA	-acetyltransferase
F0P95_RS04455	ENOG4105C01	Dihydroxy-acid dehydratase
F0P95_RS04465	ENOG4106032	Glutathionylspermidine synthase
F0P95_RS04480	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
F0P95_RS04510	ENOG4108Z0R	Transferase
F0P95_RS04570	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
F0P95_RS04575	ENOG4105MJ2	Competence protein
F0P95_RS04595	ENOG4105SUT	Transcriptional Regulator AraC Family
F0P95_RS04605	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
F0P95_RS04620	ENOG4105C0B	DNA polymerase III (alpha subunit)
F0P95_RS04675	ENOG4105C0P	Mg chelatase subunit ChlI
F0P95_RS04680	ENOG4105W0Z	cytoplasmic protein
F0P95_RS04685	ENOG4108YZA	Nitrogen regulatory protein pii
F0P95_RS04705	ENOG4105DP5	Catalyzes the biosynthesis of agmatine from arginine (By similarity)
F0P95_RS04710	ENOG4105EMU	Dehydrogenase
F0P95_RS04720	ENOG4105C75	arginyL-tRNA synthetase
F0P95_RS04725	ENOG4105W5Q	DNA repair protein (RadC
F0P95_RS04730	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
F0P95_RS04740	ENOG4107QKV	phosphomannomutase
F0P95_RS04750	ENOG4105C08	Histidine kinase
F0P95_RS04760	ENOG4105C8X	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
F0P95_RS04765	ENOG4105D9K	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
F0P95_RS04785	ENOG4105CGK	Exodeoxyribonuclease III
F0P95_RS04790	ENOG4105EYM	Major Facilitator superfamily
F0P95_RS04800	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
F0P95_RS04805	ENOG4105DR5	peptidase
F0P95_RS04810	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
F0P95_RS04850	ENOG41063SB	peptidase
F0P95_RS04855	ENOG4105CN1	protease
F0P95_RS04870	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
F0P95_RS04875	ENOG4106Z1T	Nicotinamide Mononucleotide Transporter
F0P95_RS04880	ENOG4105C26	Dehydrogenase
F0P95_RS04890	ENOG4105CV4	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) (By similarity)
F0P95_RS04900	ENOG4105FT1	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I (By similarity)
F0P95_RS04905	ENOG4107QS1	Cytochrome C Oxidase, Subunit III
F0P95_RS04935	ENOG4105DHU	Bile acid
F0P95_RS04945	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
F0P95_RS04950	ENOG4107S2Z	UPF0761 membrane protein
F0P95_RS04955	ENOG4105KTH	gatB Yqey
F0P95_RS04965	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
F0P95_RS04970	ENOG4107ZVW	dihydroneopterin aldolase
F0P95_RS04975	ENOG4105CUY	Mechanosensitive ion channel
F0P95_RS04980	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
F0P95_RS04995	ENOG4107QJT	sodium dicarboxylate symporter
F0P95_RS05005	ENOG4106G6Q	Transcriptional regulator
F0P95_RS05015	ENOG4105DTQ	mandelate racemase muconate lactonizing
F0P95_RS05030	ENOG4108KPZ	tonB-dependent Receptor
F0P95_RS05030	ENOG4108KPZ	tonB-dependent Receptor
F0P95_RS05040	ENOG4108VBV	N-Acetylmuramoyl-L-alanine amidase
F0P95_RS05050	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
F0P95_RS05055	ENOG4108VBV	N-Acetylmuramoyl-L-alanine amidase
F0P95_RS05060	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
F0P95_RS05065	ENOG4108UQS	dipeptidase
F0P95_RS05090	ENOG4105E32	cytoplasmic protein
F0P95_RS05125	ENOG4105BZS	acriflavin resistance protein
F0P95_RS05130	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
F0P95_RS05135	ENOG4105CH2	amidohydrolase
F0P95_RS05140	ENOG4107R1K	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
F0P95_RS05145	ENOG4109066	lysm domain bon superfamily protein
F0P95_RS05155	ENOG4105E9K	Isocitrate dehydrogenase
F0P95_RS05170	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
F0P95_RS05185	ENOG4105CAK	Cell division ATP-binding protein ftsE
F0P95_RS05190	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
F0P95_RS05195	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
F0P95_RS05200	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
F0P95_RS05205	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
F0P95_RS05225	ENOG4108TGY	Glutathione S-transferase
F0P95_RS05235	ENOG4105CWX	Alpha-1,2-mannosidase
F0P95_RS05240	ENOG4105ETE	Transcriptional regulator (LacI family
F0P95_RS05250	ENOG4105D7K	pfkb domain protein
F0P95_RS05275	ENOG4105C25	Primosomal protein n'
F0P95_RS05290	ENOG4107QI1	Mate efflux family protein
F0P95_RS05295	ENOG4105D07	Signal peptide peptidase, SppA
F0P95_RS05305	ENOG4107ZQV	short-chain dehydrogenase reductase
F0P95_RS05315	ENOG4105ETX	regulatoR
F0P95_RS05330	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
F0P95_RS05335	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
F0P95_RS05350	ENOG4108RPN	Protein smg homolog
F0P95_RS05355	ENOG4105C79	DNA protecting protein DprA
F0P95_RS05365	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
F0P95_RS05370	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
F0P95_RS05375	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
F0P95_RS05385	ENOG4108SHN	Glycosyl transferase, family 2
F0P95_RS05420	ENOG4107T1C	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate (By similarity)
F0P95_RS05430	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
F0P95_RS05435	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
F0P95_RS05440	ENOG4105CWX	Alpha-1,2-mannosidase
F0P95_RS05470	ENOG4108NF7	phage-type endonuclease
F0P95_RS05485	ENOG4105W5Q	DNA repair protein (RadC
F0P95_RS05515	ENOG4105CVR	type I restriction-modification system
F0P95_RS05535	ENOG4105DZR	Type I site-specific deoxyribonuclease
F0P95_RS05545	ENOG4108P8R	
F0P95_RS05580	ENOG4108VAC	response regulator
F0P95_RS05585	ENOG4108HRK	Histidine kinase
F0P95_RS05625	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
F0P95_RS05645	ENOG4105EMN	RNA polymerase sigma factor
F0P95_RS05655	ENOG4105EUJ	GTP cyclohydrolase i
F0P95_RS05660	ENOG4105EXX	Deoxyribodipyrimidine photolyase-related protein
F0P95_RS05685	ENOG4107XTP	(EAL) domain protein
F0P95_RS05690	ENOG4105BZU	Histidine kinase
F0P95_RS05705	ENOG4105BZU	Histidine kinase
F0P95_RS05735	ENOG4108KPZ	tonB-dependent Receptor
F0P95_RS05740	ENOG4105GRZ	Ycii-related protein
F0P95_RS05745	ENOG4105GRZ	Ycii-related protein
F0P95_RS05760	ENOG4105KCV	RNA signal recognition particle 4.5S RNA
F0P95_RS05765	ENOG4105CHP	RNA polymerase
F0P95_RS05775	ENOG4105C2F	Histidine kinase
F0P95_RS05780	ENOG4108VAC	response regulator
F0P95_RS05800	ENOG4105C9K	Endothelin-converting enzyme 1
F0P95_RS05805	ENOG4105BZU	Histidine kinase
F0P95_RS05815	ENOG4105C8E	extradiol ring-cleavage dioxygenase class IIi protein subunit b
F0P95_RS05820	ENOG4105EEQ	Na H antiporter
F0P95_RS05845	ENOG4105ER2	Ompa motb domain protein
F0P95_RS05850	ENOG4107RD7	Flagellar Motor Protein, MotA
F0P95_RS05870	ENOG4105EW9	transcriptional regulator AsnC family
F0P95_RS05875	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
F0P95_RS05900	ENOG4105I08	Pseudouridine synthase
F0P95_RS05905	ENOG4107UW8	HAD-superfamily hydrolase subfamily IA variant 3
F0P95_RS05915	ENOG4108VPT	UPF0234 protein
F0P95_RS05925	ENOG4108EHX	EamA-like transporter family
F0P95_RS05930	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
F0P95_RS05935	ENOG4108UMI	ABC transporter, permease
F0P95_RS05940	ENOG4105D01	(LipO)protein
F0P95_RS05960	ENOG4107QSN	dihydrolipoamide acetyltransferase
F0P95_RS05965	ENOG4107QN2	dihydrolipoyl dehydrogenase
F0P95_RS05980	ENOG4107RAZ	it plays a direct role in the translocation of protons across the membrane (By similarity)
F0P95_RS05985	ENOG4105KY6	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
F0P95_RS05990	ENOG4107Z6K	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
F0P95_RS05995	ENOG4107S15	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
F0P95_RS06000	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
F0P95_RS06005	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
F0P95_RS06010	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
F0P95_RS06015	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
F0P95_RS06025	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
F0P95_RS06040	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
F0P95_RS06060	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
F0P95_RS06065	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
F0P95_RS06080	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
F0P95_RS06085	ENOG4105C19	ABC transporter
F0P95_RS06095	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
F0P95_RS06105	ENOG4108YAB	Invasion protein
F0P95_RS06155	ENOG4105E3B	Multicopper oxidase
F0P95_RS06170	ENOG4105DGW	oligopeptidase A
F0P95_RS06215	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
F0P95_RS06220	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
F0P95_RS06225	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
F0P95_RS06230	ENOG4105CUP	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity)
F0P95_RS06240	ENOG4108374	Joins Ado-cobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin) (By similarity)
F0P95_RS06260	ENOG4107ZIF	6-carboxy-5,6,7,8-tetrahydropterin synthase
F0P95_RS06265	ENOG4105C1J	atp-dependent rna helicase
F0P95_RS06275	ENOG4108RXX	maleylacetoacetate isomerase
F0P95_RS06305	ENOG4105C28	cystathionine
F0P95_RS06310	ENOG4108DMA	Nad-dependent epimerase dehydratase
F0P95_RS06315	ENOG4105C0K	Gdp-mannose 4,6-dehydratase
F0P95_RS06325	ENOG4105CTC	Lipopolysaccharide biosynthesis protein-like protein
F0P95_RS06330	ENOG4105EY8	ABC transporter
F0P95_RS06340	ENOG4107RFD	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
F0P95_RS06365	ENOG4105C10	Electron transfer flavoprotein
F0P95_RS06370	ENOG4105BZJ	Electron transfer flavoprotein
F0P95_RS06385	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
F0P95_RS06395	ENOG4107QHF	type ii secretion system protein e
F0P95_RS06405	ENOG4108VAU	general secretion pathway protein G
F0P95_RS06445	ENOG4105GVR	general secretion pathway protein D
F0P95_RS06465	ENOG4107QKV	phosphomannomutase
F0P95_RS06480	ENOG4105EYF	MMPL domain protein
F0P95_RS06495	ENOG4108NEV	two component transcriptional regulator, LytTR family
F0P95_RS06500	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
F0P95_RS06515	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
F0P95_RS06535	ENOG4108IYU	L-aspartate oxidase
F0P95_RS06580	ENOG4105WD1	Membrane
F0P95_RS06590	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
F0P95_RS06615	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
F0P95_RS06630	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
F0P95_RS06635	ENOG4105BZS	acriflavin resistance protein
F0P95_RS06650	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
F0P95_RS06655	ENOG4105CD8	aminopeptidase N
F0P95_RS06680	ENOG4107T4Z	adenosine kinase
F0P95_RS06690	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
F0P95_RS06700	ENOG4105CJN	penicillin-binding protein
F0P95_RS06705	ENOG4105CNI	cell division protein FtsW
F0P95_RS06710	ENOG4105CVE	Lytic murein transglycosylase
F0P95_RS06720	ENOG4105DZ1	carboxypeptidase
F0P95_RS06740	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
F0P95_RS06745	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
F0P95_RS06750	ENOG4105CN1	protease
F0P95_RS06765	ENOG4108J5G	6-phosphogluconate dehydrogenase
F0P95_RS06775	ENOG4105BZU	Histidine kinase
F0P95_RS06785	ENOG4105BZU	Histidine kinase
F0P95_RS06790	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
F0P95_RS06815	ENOG41082W1	Cupin 2, conserved barrel domain protein
F0P95_RS06820	ENOG4105E2D	ec 3.2.1.52
F0P95_RS06825	ENOG4105EHZ	conserved protein UCP016719
F0P95_RS06830	ENOG4105E2D	ec 3.2.1.52
F0P95_RS06840	ENOG4105CHC	glucokinase (EC 2.7.1.2)
F0P95_RS06845	ENOG4105E2D	ec 3.2.1.52
F0P95_RS06855	ENOG4105CHC	glucokinase (EC 2.7.1.2)
F0P95_RS06860	ENOG4105EDR	glucose galactose transporter
F0P95_RS06865	ENOG4105ETE	Transcriptional regulator (LacI family
F0P95_RS06870	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
F0P95_RS06875	ENOG4105CE4	GlcNAc 6-P deacetylase
F0P95_RS06890	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
F0P95_RS06915	ENOG4108Z33	Thiol disulfide Interchange Protein
F0P95_RS06925	ENOG4106RE7	Cytochrome
F0P95_RS06930	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
F0P95_RS06935	ENOG4105CY0	Metallo-Beta-Lactamase
F0P95_RS06955	ENOG4108RXX	maleylacetoacetate isomerase
F0P95_RS06985	ENOG4105C4W	S-formylglutathione hydrolase
F0P95_RS07005	ENOG4108RMV	DegV Family
F0P95_RS07010	ENOG4105CI2	imidazolone-5-propionate hydrolase
F0P95_RS07015	ENOG41069H0	dihydroorotase EC 3.5.2.3
F0P95_RS07035	ENOG4105C1J	atp-dependent rna helicase
F0P95_RS07055	ENOG4105CHM	Aminotransferase
F0P95_RS07060	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
F0P95_RS07070	ENOG4105FQP	Beta-lactamase
F0P95_RS07075	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
F0P95_RS07085	ENOG4106KR7	LysR family Transcriptional regulator
F0P95_RS07090	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
F0P95_RS07095	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
F0P95_RS07100	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
F0P95_RS07105	ENOG4105D6U	Sodium Glutamate Symporter
F0P95_RS07120	ENOG4106KNT	transcriptional regulator
F0P95_RS07135	ENOG4105C6K	Malic enzyme
F0P95_RS07165	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
F0P95_RS07175	ENOG4105D1S	lipid A biosynthesis
F0P95_RS07180	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
F0P95_RS07185	ENOG4105DFG	type I secretion outer membrane protein
F0P95_RS07190	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
F0P95_RS07210	ENOG4105BZU	Histidine kinase
F0P95_RS07240	ENOG4105C2M	dna polymerase I
F0P95_RS07250	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
F0P95_RS07275	ENOG4105W8H	transhydrogenase (subunit alpha
F0P95_RS07285	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
F0P95_RS07300	ENOG4105CM2	brancheD-chain amino acid aminotransferase
F0P95_RS07305	ENOG4108Z66	YbaK ebsC protein
F0P95_RS07320	ENOG4105CS1	NAD(P)H quinone oxidoreductase
F0P95_RS07325	ENOG4107S2Z	UPF0761 membrane protein
F0P95_RS07330	ENOG4107QXG	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
F0P95_RS07335	ENOG4105CSR	polyphosphate kinase 2
F0P95_RS07360	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
F0P95_RS07365	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
F0P95_RS07370	ENOG4105DJQ	tetratricopeptide tpr_2 repeat protein
F0P95_RS07380	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
F0P95_RS07390	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
F0P95_RS07400	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
F0P95_RS07405	ENOG4105C3G	gtp-binding protein
F0P95_RS07410	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
F0P95_RS07415	ENOG4108UHX	Involved in the hydrolysis of glutamine to glutamate and ammonia. Channels an ammonia molecule to PdxS (By similarity)
F0P95_RS07420	ENOG4105D44	asparaginase
F0P95_RS07440	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
F0P95_RS07450	ENOG4105PM1	preprotein translocase subunit SecE
F0P95_RS07455	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
F0P95_RS07460	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
F0P95_RS07465	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
F0P95_RS07470	ENOG4108VZM	50s ribosomal protein L10
F0P95_RS07475	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
F0P95_RS07480	ENOG4107QIH	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
F0P95_RS07485	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
F0P95_RS07490	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
F0P95_RS07495	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
F0P95_RS07500	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
F0P95_RS07505	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
F0P95_RS07515	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
F0P95_RS07520	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
F0P95_RS07525	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
F0P95_RS07530	ENOG41080KG	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
F0P95_RS07535	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
F0P95_RS07540	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
F0P95_RS07545	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
F0P95_RS07550	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
F0P95_RS07555	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
F0P95_RS07565	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
F0P95_RS07575	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
F0P95_RS07580	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
F0P95_RS07585	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
F0P95_RS07590	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
F0P95_RS07600	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
F0P95_RS07605	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
F0P95_RS07610	ENOG41087MT	50S ribosomal protein L30
F0P95_RS07615	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
F0P95_RS07620	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
F0P95_RS07625	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
F0P95_RS07635	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
F0P95_RS07640	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
F0P95_RS07645	ENOG4108ZT0	50S ribosomal protein l17
F0P95_RS07650	ENOG41080I0	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity)
F0P95_RS07655	ENOG4105C7V	phospho-2-dehydro-3-deoxyheptonate aldolase
F0P95_RS07660	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
F0P95_RS07670	ENOG4105CI3	gtp-binding protein typa
F0P95_RS07675	ENOG4107XH4	PPIases accelerate the folding of proteins (By similarity)
F0P95_RS07680	ENOG4105D9Z	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
F0P95_RS07685	ENOG4105D3G	Pseudouridine synthase
F0P95_RS07690	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
F0P95_RS07705	ENOG4105BZU	Histidine kinase
F0P95_RS07710	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
F0P95_RS07715	ENOG4105E0X	reductase
F0P95_RS07725	ENOG4107U7B	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
F0P95_RS07730	ENOG4108K3A	Glutathione S-transferase
F0P95_RS07740	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
F0P95_RS07750	ENOG4105CDV	Ompa motb domain protein
F0P95_RS07760	ENOG4105FE9	pseudouridine synthase
F0P95_RS07780	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
F0P95_RS07790	ENOG4105DE7	Sulfate ABC transporter periplasmic sulfate-binding protein
F0P95_RS07795	ENOG4108I5D	sulfate abc transporter
F0P95_RS07805	ENOG4108IJ6	ABC transporter
F0P95_RS07815	ENOG4105CPQ	Dehydrogenase
F0P95_RS07830	ENOG4107RPC	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
F0P95_RS07840	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
F0P95_RS07855	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
F0P95_RS07860	ENOG4105ED9	Protein of unknown function (DUF455)
F0P95_RS07875	ENOG4105F10	Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity)
F0P95_RS07885	ENOG4105BZF	Glycosyl transferase (Group 1
F0P95_RS07890	ENOG4105C9X	ppx gppa phosphatase
F0P95_RS07895	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
F0P95_RS07900	ENOG4105BZU	Histidine kinase
F0P95_RS07905	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
F0P95_RS07910	ENOG4105ERG	peptidase m48, ste24p
F0P95_RS07915	ENOG4105VW4	glutaredoxin 3
F0P95_RS07925	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
F0P95_RS07965	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
F0P95_RS07975	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
F0P95_RS08010	ENOG4107UUG	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity)
F0P95_RS08015	ENOG41068JE	domain protein
F0P95_RS08020	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
F0P95_RS08035	ENOG4107RZZ	dna polymerase iii epsilon subunit
F0P95_RS08040	ENOG4108ZF3	Phosphatase
F0P95_RS08055	ENOG4105DKP	glycosyl transferase, family 9
F0P95_RS08060	ENOG4108W7E	Catalyzes the ATP-dependent phosphorylation of the 3- deoxy-D-manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position (By similarity)
F0P95_RS08065	ENOG4107UV6	ribonuclease Z
F0P95_RS08080	ENOG4107QMP	dna polymerase iii subunits gamma and tau
F0P95_RS08095	ENOG4105K59	histidine triad (HIT) protein
F0P95_RS08120	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
F0P95_RS08130	ENOG41089I4	Inherit from COG: Glycosyl transferase, family 2
F0P95_RS08145	ENOG4105FCQ	metal-binding, possibly nucleic acid-binding protein
F0P95_RS08150	ENOG4105VGS	50s ribosomal protein l32
F0P95_RS08155	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
F0P95_RS08165	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
F0P95_RS08170	ENOG4105CHR	reductase
F0P95_RS08180	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
F0P95_RS08190	ENOG4105HHA	aminodeoxychorismate lyase
F0P95_RS08195	ENOG4107QRG	dna polymerase iii
F0P95_RS08215	ENOG4105DGI	Alkaline phosphatase
F0P95_RS08245	ENOG4105II7	pyrroline-5-carboxylate reductase
F0P95_RS08250	ENOG4105CZX	twitching motility protein
F0P95_RS08255	ENOG4105CZX	twitching motility protein
F0P95_RS08275	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
F0P95_RS08280	ENOG4108UJU	UPF0301 protein
F0P95_RS08285	ENOG4107Y66	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
F0P95_RS08290	ENOG4105CXT	aspartate transcarbamylase
F0P95_RS08305	ENOG4105CJW	magnesium transporter
F0P95_RS08310	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
F0P95_RS08325	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
F0P95_RS08330	ENOG4105D1C	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion (By similarity)
F0P95_RS08335	ENOG4107RM2	PTS IIA-like nitrogen-regulatory protein PtsN
F0P95_RS08340	ENOG41080QH	sigma 54 modulation protein ribosomal protein S30EA
F0P95_RS08345	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
F0P95_RS08350	ENOG4108IUZ	ABC transporter
F0P95_RS08370	ENOG4105C2X	Arabinose 5-phosphate isomerase
F0P95_RS08380	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
F0P95_RS08390	ENOG4106SNF	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
F0P95_RS08395	ENOG4105C34	Pseudouridine synthase
F0P95_RS08410	ENOG4105KIR	Thiol-disulfide oxidoreductase dcc
F0P95_RS08420	ENOG4105BZP	glycoside hydrolase 15-related
F0P95_RS08425	ENOG4108K4C	ec 3.1.3.12
F0P95_RS08430	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
F0P95_RS08455	ENOG4105E18	UPF0276 protein
F0P95_RS08465	ENOG4105CA0	peroxidase
F0P95_RS08475	ENOG4105PE1	Receptor
F0P95_RS08485	ENOG4108SF5	RNA Polymerase
F0P95_RS08490	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
F0P95_RS08535	ENOG4107TII	Recombinase
F0P95_RS08550	ENOG4105CR8	Transcriptional regulator
F0P95_RS08555	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
F0P95_RS08560	ENOG4107RNH	Outer membrane receptor FepA
F0P95_RS08565	ENOG4105C5H	ABC transporter
F0P95_RS08570	ENOG4105ETT	transcriptional Regulator, LysR family
F0P95_RS08585	ENOG4107QPV	Serine Threonine protein kinase
F0P95_RS08600	ENOG4105C9M	aspartyl-trna synthetase
F0P95_RS08620	ENOG4107RNH	Outer membrane receptor FepA
F0P95_RS08630	ENOG4105CDY	transcriptional regulatory protein
F0P95_RS08640	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
F0P95_RS08645	ENOG4105DFH	Transport of potassium into the cell (By similarity)
F0P95_RS08650	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
F0P95_RS08655	ENOG4107YD3	Thioesterase
F0P95_RS08660	ENOG4105E02	MotA TolQ exbB proton channel
F0P95_RS08665	ENOG4105SG9	biopolymer transport protein, ExbD
F0P95_RS08680	ENOG4105KCK	Peptidoglycan-associated lipoprotein
F0P95_RS08690	ENOG4107VRB	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
F0P95_RS08710	ENOG4108DT4	serine threonine protein kinase
F0P95_RS08715	ENOG4105C9U	ATP-dependent DNA helicase RecQ
F0P95_RS08725	ENOG4105CQ7	ATP-dependent helicase
F0P95_RS08740	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
F0P95_RS08755	ENOG4105BZ4	penicillin-binding protein
F0P95_RS08765	ENOG4105DVT	helicase
F0P95_RS08770	ENOG41072GX	Peptidase M22 Glycoprotease
F0P95_RS08780	ENOG4105JAB	phenazine biosynthesis protein, phzf family
F0P95_RS08790	ENOG4105CFH	Aspartokinase
F0P95_RS08800	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
F0P95_RS08810	ENOG4105EAH	synthase
F0P95_RS08815	ENOG4105CG3	alpha amylase, catalytic region
F0P95_RS08830	ENOG4107RBJ	symporter
F0P95_RS08860	ENOG4108UUM	single-stranded DNA-binding protein
F0P95_RS08865	ENOG4105CAU	Arsenical resistance protein, ArsH
F0P95_RS08880	ENOG4105D6J	arsenicaL-resistance protein
F0P95_RS08890	ENOG4106S2D	Transcriptional regulator
F0P95_RS08900	ENOG4107S8C	mandelate racemase muconate lactonizing
F0P95_RS08910	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
F0P95_RS08920	ENOG4105DUX	Transporter
F0P95_RS08925	ENOG4105EPD	Oligopeptide transporter, Opt family
F0P95_RS08930	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
F0P95_RS08945	ENOG4105VCD	cytoplasmic protein
F0P95_RS08950	ENOG4105D22	carbon starvation protein
F0P95_RS08955	ENOG4105EUB	pirin domain protein
F0P95_RS08965	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
F0P95_RS08970	ENOG4105EUB	pirin domain protein
F0P95_RS08980	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
F0P95_RS09000	ENOG4105C9K	Endothelin-converting enzyme 1
F0P95_RS09015	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
F0P95_RS09020	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
F0P95_RS09025	ENOG4108JA2	transcriptioN-repair coupling factor
F0P95_RS09035	ENOG4105D6S	protein involved in catabolism of external DNA
F0P95_RS09040	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
F0P95_RS09045	ENOG4105EB3	Histidine kinase
F0P95_RS09050	ENOG4105BZU	Histidine kinase
F0P95_RS09055	ENOG4105CT7	inner membrane cred family protein
F0P95_RS09085	ENOG4108TGP	Thioesterase superfamily protein
F0P95_RS09090	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
F0P95_RS09100	ENOG4105K46	50S ribosomal protein l27
F0P95_RS09110	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
F0P95_RS09120	ENOG4105CJR	Integral membrane protein (MviN
F0P95_RS09125	ENOG4105DTN	riboflavin biosynthesis protein ribF
F0P95_RS09130	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
F0P95_RS09135	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
F0P95_RS09140	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
F0P95_RS09155	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
F0P95_RS09175	ENOG4105E2S	oxidase) subunit II
F0P95_RS09180	ENOG4105BZ9	Cytochrome C oxidase, subunit I
F0P95_RS09185	ENOG4105CCU	oxidase (Subunit III)
F0P95_RS09190	ENOG41090KH	cytochrome o ubiquinol oxidase (subunit iv)
F0P95_RS09195	ENOG4105BZU	Histidine kinase
F0P95_RS09200	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
F0P95_RS09215	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
F0P95_RS09220	ENOG4105EA8	2-Nitropropane dioxygenase
F0P95_RS09235	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
F0P95_RS09240	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
F0P95_RS09245	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
F0P95_RS09250	ENOG4105E98	transcriptional regulator DeoR family
F0P95_RS09255	ENOG4105C6Q	that is required for full activity and stability of the Y subunit. Could have a chaperone-like function for the proper and stable folding of
F0P95_RS09260	ENOG4105EZX	Catalyzes the phosphorylation of N-acetyl-D-glucosamine (GlcNAc) derived from cell-wall degradation, yielding GlcNAc-6-P (By similarity)
F0P95_RS09265	ENOG4105E70	isomerase
F0P95_RS09280	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
F0P95_RS09285	ENOG4105EPC	oxidoreductase
F0P95_RS09290	ENOG4107QJQ	Mate efflux family protein
F0P95_RS09300	ENOG4105VEJ	Heat shock protein
F0P95_RS09310	ENOG4105CH6	catalase
F0P95_RS09320	ENOG4108Z3G	3H domain protein
F0P95_RS09340	ENOG4105CXN	decarboxylase
F0P95_RS09345	ENOG4105D5Q	Arginine ornithine antiporter
F0P95_RS09360	ENOG4105BZU	Histidine kinase
F0P95_RS09365	ENOG4107ZT5	Thiol disulfide interchange protein
F0P95_RS09370	ENOG4108KHN	disulfide isomerase, thiol-disulfide oxidase
F0P95_RS09395	ENOG4105C59	p-type ATPase
F0P95_RS09415	ENOG4105D6P	C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex (By similarity)
F0P95_RS09430	ENOG4105EUH	cytochrome C oxidase, cbb3-type, subunit i
F0P95_RS09435	ENOG41090JD	Blue (Type 1) copper domain protein
F0P95_RS09440	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
F0P95_RS09445	ENOG4105EMN	RNA polymerase sigma factor
F0P95_RS09455	ENOG4105C0H	protease
F0P95_RS09460	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
F0P95_RS09465	ENOG4105C3F	Signal peptidase i
F0P95_RS09475	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
F0P95_RS09480	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
F0P95_RS09485	ENOG41071DT	Involved in DNA repair and RecF pathway recombination (By similarity)
F0P95_RS09495	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
F0P95_RS09505	ENOG4107ZXU	DSBA oxidoreductase
F0P95_RS09510	ENOG4107QPA	Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides (By similarity)
F0P95_RS09515	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
F0P95_RS09520	ENOG4107RHB	Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates (By similarity)
F0P95_RS09525	ENOG4105VEQ	Cold shock protein
F0P95_RS09530	ENOG41061H0	Monooxygenase
F0P95_RS09535	ENOG4105CSU	acyl-Coa dehydrogenase
F0P95_RS09550	ENOG4105CHU	acetyl-coa acetyltransferase
F0P95_RS09565	ENOG4105D5P	Methylmalonyl-coA mutase
F0P95_RS09570	ENOG4105BZU	Histidine kinase
F0P95_RS09575	ENOG4105EBE	Peptidase U61, LD-carboxypeptidase A
F0P95_RS09585	ENOG4105E2D	ec 3.2.1.52
F0P95_RS09590	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
F0P95_RS09595	ENOG4105E0F	Histidine kinase
F0P95_RS09605	ENOG4105DH5	Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis (By similarity)
F0P95_RS09610	ENOG4106HNH	Acyl-transferase
F0P95_RS09635	ENOG4105CZM	Major Facilitator
F0P95_RS09650	ENOG4107RZC	phospholipase d
F0P95_RS09655	ENOG4107QV7	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system) (By similarity)
F0P95_RS09675	ENOG4108VKG	metal-dependent hydrolase
F0P95_RS09685	ENOG4105KSC	Transcriptional regulator, TraR DksA family
F0P95_RS09720	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
F0P95_RS09760	ENOG4105M4H	endoribonuclease L-psp
F0P95_RS09770	ENOG4106BRA	Membrane
F0P95_RS09785	ENOG4105KA3	membrAne
F0P95_RS09790	ENOG4105RA2	Membrane
F0P95_RS09795	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
F0P95_RS09805	ENOG4105CSH	Transporter
F0P95_RS09810	ENOG4105W3S	hemerythrin-like, metal-binding protein
F0P95_RS09820	ENOG4105ETX	regulatoR
F0P95_RS09850	ENOG4105CJP	fad dependent oxidoreductase
F0P95_RS09860	ENOG4107RUE	extracellular solute-binding protein family 1
F0P95_RS09865	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
F0P95_RS09870	ENOG4105F38	ABC transporter, permease
F0P95_RS09875	ENOG4105D38	putrescine abc transporter
F0P95_RS09880	ENOG4105C26	Dehydrogenase
F0P95_RS09900	ENOG4108JU5	Magnesium and cobalt efflux protein
F0P95_RS09915	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
F0P95_RS09925	ENOG4105C9A	Phoh family
F0P95_RS09930	ENOG4108MHR	Repressor involved in choline regulation of the bet genes (By similarity)
F0P95_RS09940	ENOG4105CJ1	ABC, transporter
F0P95_RS09945	ENOG4105CJ1	ABC, transporter
F0P95_RS09950	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
F0P95_RS09955	ENOG4105E4C	Lytic transglycosylase catalytic
F0P95_RS09960	ENOG4108R5F	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
F0P95_RS09965	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
F0P95_RS09970	ENOG4105EIX	cytochrome c1
F0P95_RS09975	ENOG4107MKT	Stringent starvation protein a
F0P95_RS09980	ENOG4105KB2	stringent starvation protein b
F0P95_RS09995	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
F0P95_RS10005	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
F0P95_RS10010	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
F0P95_RS10020	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
F0P95_RS10025	ENOG4105M2J	Glutaredoxin
F0P95_RS10030	ENOG4105E1F	short-chain dehydrogenase reductase
F0P95_RS10035	ENOG41076UM	multiple antibiotic resistance (MarC)-related protein
F0P95_RS10040	ENOG4108KPZ	tonB-dependent Receptor
F0P95_RS10045	ENOG4105EWT	decarboxylase family
F0P95_RS10050	ENOG4108HRK	Histidine kinase
F0P95_RS10075	ENOG4105CWU	Biogenesis protein
F0P95_RS10095	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
F0P95_RS10105	ENOG4105C22	threonyL-tRNA synthetase
F0P95_RS10110	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
F0P95_RS10125	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
F0P95_RS10130	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
F0P95_RS10155	ENOG4105C58	cytochrome c oxidase accessory protein ccog
F0P95_RS10170	ENOG4105D4P	Coproporphyrinogen iii oxidase
F0P95_RS10180	ENOG4107QQG	Dehydrogenase
F0P95_RS10185	ENOG4105CBC	glutamate synthase
F0P95_RS10205	ENOG4105C72	UPF0176 protein
F0P95_RS10210	ENOG4105DEN	Luciferase family
F0P95_RS10230	ENOG4105CJ3	phosphate transporter
F0P95_RS10240	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
F0P95_RS10250	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
F0P95_RS10255	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
F0P95_RS10265	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
F0P95_RS10270	ENOG4105XX3	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
F0P95_RS10275	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
F0P95_RS10280	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
F0P95_RS10285	ENOG4106NZV	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity)
F0P95_RS10290	ENOG4108DG9	Smr protein MutS2
F0P95_RS10295	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
F0P95_RS10305	ENOG4108UM1	dedA family
F0P95_RS10310	ENOG4108K5P	(LipO)protein
F0P95_RS10325	ENOG4105HBR	Rna-binding protein
F0P95_RS10330	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
F0P95_RS10335	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
F0P95_RS10345	ENOG4105EEI	dihydropteroate synthase
F0P95_RS10350	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
F0P95_RS10360	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
F0P95_RS10375	ENOG4105DJ4	phosphatidylserine decarboxylase
F0P95_RS10385	ENOG4105C76	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity)
F0P95_RS10395	ENOG4105C5I	Dehydrogenase
F0P95_RS10400	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
F0P95_RS10415	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
F0P95_RS10420	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
F0P95_RS10440	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
F0P95_RS10445	ENOG4105EXC	Acyl-transferase
F0P95_RS10450	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
F0P95_RS10455	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
F0P95_RS10460	ENOG4107BJW	polysaccharide deacetylase
F0P95_RS10465	ENOG4107QPH	glycogen) synthase
F0P95_RS10475	ENOG4105CP7	Triose-phosphate isomerase
F0P95_RS10490	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
F0P95_RS10495	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
F0P95_RS10500	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
F0P95_RS10505	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
F0P95_RS10515	ENOG4107QIZ	NADH dehydrogenase
F0P95_RS10520	ENOG4107R0R	NADH dehydrogenase subunit g
F0P95_RS10530	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
F0P95_RS10535	ENOG4105DF2	NADH dehydrogenase subunit j
F0P95_RS10550	ENOG4105C8S	subunit m
F0P95_RS10555	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
F0P95_RS10565	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
F0P95_RS10570	ENOG4105CHV	Transcription elongation factor NusA
F0P95_RS10575	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
F0P95_RS10580	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
F0P95_RS10590	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
F0P95_RS10605	ENOG4108PAU	MotA TolQ exbB proton channel
F0P95_RS10610	ENOG4105M15	transport protein ExbD
F0P95_RS10615	ENOG4105BZ1	(ABC) transporter
F0P95_RS10620	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
F0P95_RS10625	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
F0P95_RS10640	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
F0P95_RS10675	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
F0P95_RS10685	ENOG4105CSU	acyl-Coa dehydrogenase
F0P95_RS10705	ENOG4108S3W	Anti-feci sigma factor, fecr
F0P95_RS10710	ENOG4105CI2	imidazolone-5-propionate hydrolase
F0P95_RS10715	ENOG4107RT5	aminobenzoyl-glutamate utilization protein B
F0P95_RS10720	ENOG4105QNF	Outer membrane lipoprotein
F0P95_RS10745	ENOG4105E6M	Sulphatase-modifying factor protein
F0P95_RS10755	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
F0P95_RS10760	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
F0P95_RS10765	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
F0P95_RS10770	ENOG4105K8N	protein family UPF0079, ATPase
F0P95_RS10775	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
F0P95_RS10780	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
F0P95_RS10800	ENOG4105CHR	reductase
F0P95_RS10805	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
F0P95_RS10810	ENOG4105D0M	Protease HtpX homolog
F0P95_RS10835	ENOG4105BZU	Histidine kinase
F0P95_RS10845	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
F0P95_RS10855	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
F0P95_RS10865	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
F0P95_RS10895	ENOG4105CD3	dihydroorotase
F0P95_RS10915	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
F0P95_RS10920	ENOG4105C8N	cysteinyl-tRNA synthetase
F0P95_RS10930	ENOG4105DBV	ornithine carbamoyltransferase
F0P95_RS10935	ENOG4105CDH	Citrulline--aspartate ligase
F0P95_RS10945	ENOG4105CAS	nag kinase
F0P95_RS10960	ENOG4105CH7	arginosuccinase
F0P95_RS10970	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
F0P95_RS11000	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
F0P95_RS11005	ENOG4105C4M	(Ubiquinol oxidase) subunit I
F0P95_RS11010	ENOG4108JJ9	ABC, transporter
F0P95_RS11015	ENOG4108JJ8	(ABC) transporter
F0P95_RS11025	ENOG4105DWV	Homoserine O-trans-acetylase
F0P95_RS11035	ENOG4106FI7	cytochrome c-type biogenesis protein
F0P95_RS11040	ENOG4105KWW	Biogenesis protein
F0P95_RS11045	ENOG4107QX9	Thiol disulfide interChange protein
F0P95_RS11050	ENOG4105DA4	cytochrome c-type biogenesis protein
F0P95_RS11055	ENOG4108ZKK	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity)
F0P95_RS11065	ENOG41060IM	Heme exporter protein
F0P95_RS11075	ENOG4105CA5	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity)
F0P95_RS11085	ENOG4105CHM	Aminotransferase
F0P95_RS11105	ENOG4105FE9	pseudouridine synthase
F0P95_RS11110	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
F0P95_RS11115	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
F0P95_RS11120	ENOG4105K9H	YciI-like protein
F0P95_RS11130	ENOG4105ETE	Transcriptional regulator (LacI family
F0P95_RS11150	ENOG4105F0P	binding-protein-dependent transport systems inner membrane Component
F0P95_RS11155	ENOG4105DRS	transport system, permease
F0P95_RS11165	ENOG4108UHU	Aldolase
F0P95_RS11170	ENOG4105C01	Dihydroxy-acid dehydratase
F0P95_RS11180	ENOG4105CHC	glucokinase (EC 2.7.1.2)
F0P95_RS11195	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
F0P95_RS11220	ENOG4105E33	succinate dehydrogenase
F0P95_RS11225	ENOG410681N	tpr repeat protein
F0P95_RS11235	ENOG4105D60	lipoprotein releasing system transmembrane protein
F0P95_RS11250	ENOG4105KMG	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes (By similarity)
F0P95_RS11255	ENOG4105CEN	a g-specific adenine glycosylase
F0P95_RS11260	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
F0P95_RS11270	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
F0P95_RS11275	ENOG4106H78	methyltransferase
F0P95_RS11280	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
F0P95_RS11290	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
F0P95_RS11295	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
F0P95_RS11305	ENOG4105DKK	Benzoate
F0P95_RS11310	ENOG4105DFA	alanine racemase domain protein
F0P95_RS11315	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
F0P95_RS11320	ENOG4105C8F	Beta-lactamase domain protein
F0P95_RS11335	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
F0P95_RS11340	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
F0P95_RS11360	ENOG4105CC0	LysR family Transcriptional regulator
F0P95_RS11390	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
F0P95_RS11400	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
F0P95_RS11405	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
F0P95_RS11410	ENOG4105VIE	preprotein translocase, subunit YajC
F0P95_RS11415	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
F0P95_RS11420	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
F0P95_RS11425	ENOG4105RKW	reductase (By
F0P95_RS11430	ENOG4105BZU	Histidine kinase
F0P95_RS11435	ENOG4105CBX	hi0933 family
F0P95_RS11440	ENOG4108VWS	Yaeq family
F0P95_RS11445	ENOG4108UPT	UPF0178 protein
F0P95_RS11455	ENOG4105CNG	UPF0061 protein
F0P95_RS11480	ENOG4108NEV	two component transcriptional regulator, LytTR family
F0P95_RS11490	ENOG4105C1J	atp-dependent rna helicase
F0P95_RS11495	ENOG4105HMI	Membrane
F0P95_RS11500	ENOG4105DUM	transcriptional regulator, lysR family
F0P95_RS11505	ENOG4105C5H	ABC transporter
F0P95_RS11525	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
F0P95_RS11535	ENOG4105DUX	Transporter
F0P95_RS11560	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
F0P95_RS11565	ENOG4105DGW	oligopeptidase A
F0P95_RS11570	ENOG4108V06	Glutathione peroxidase
F0P95_RS11575	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
F0P95_RS11580	ENOG4105DP0	ferredoxin-NADP reductase
F0P95_RS11595	ENOG4105EN6	Membrane
F0P95_RS11600	ENOG4107GFK	fumarate
F0P95_RS11620	ENOG4105K89	arsenate reductase
F0P95_RS11625	ENOG4105HDD	phospholipase
F0P95_RS11635	ENOG4105VEQ	Cold shock protein
F0P95_RS11650	ENOG4105CUZ	uba thif-type nad fad binding protein
F0P95_RS11655	ENOG4105EYA	deoxyribonuclease
F0P95_RS11695	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
F0P95_RS11705	ENOG4105D1N	poly(r)-hydroxyalkanoic acid synthase, class
F0P95_RS11710	ENOG4105M0Y	
F0P95_RS11725	ENOG4105BZM	domain protein
F0P95_RS11760	ENOG4105DQE	DNA ligase
F0P95_RS11765	ENOG4105K3G	Periplasmic Protein
F0P95_RS11775	ENOG4105DQ4	alcohol dehydrogenase
F0P95_RS11785	ENOG4105CH2	amidohydrolase
F0P95_RS11790	ENOG4105NCT	RNA Polymerase
F0P95_RS11795	ENOG4108ZJD	Protein of unknown function (DUF1109)
F0P95_RS11830	ENOG4105FQP	Beta-lactamase
F0P95_RS11835	ENOG4105CN1	protease
F0P95_RS11850	ENOG4108ZXE	
F0P95_RS11860	ENOG4105KWI	UPF0339 protein
F0P95_RS11880	ENOG4106N3A	copper homeostasis protein cutc
F0P95_RS11900	ENOG4105D1H	recombination factor protein RarA
F0P95_RS11905	ENOG4107Y7W	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity)
F0P95_RS11920	ENOG4105C3M	thioredoxin reductase
F0P95_RS11925	ENOG4105DIN	metallophosphoesterase
F0P95_RS11945	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
F0P95_RS11955	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
F0P95_RS11960	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
F0P95_RS11975	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
F0P95_RS11980	ENOG41075W9	High frequency lysogenization protein HflD homolog
F0P95_RS11990	ENOG4105BZU	Histidine kinase
F0P95_RS12000	ENOG4105BZU	Histidine kinase
F0P95_RS12005	ENOG4105BZU	Histidine kinase
F0P95_RS12035	ENOG4108ZC9	flagellar basal-body rod protein flgc
F0P95_RS12040	ENOG410822I	Flagellar hook capping protein
F0P95_RS12045	ENOG4105BZE	flagellar hook protein, FlgE
F0P95_RS12050	ENOG4108KPB	Flagellar basal-body rod protein FlgF
F0P95_RS12055	ENOG4105CGA	flagellar basal-body rod protein FlgG
F0P95_RS12060	ENOG4107W7W	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
F0P95_RS12070	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
F0P95_RS12075	ENOG4105E1Q	flagellar hook-associated protein
F0P95_RS12080	ENOG4105DTJ	flagellar hook-associated protein
F0P95_RS12095	ENOG4105DTS	flagellar hook-associated
F0P95_RS12100	ENOG4105MQ3	flagellar protein FliS
F0P95_RS12120	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
F0P95_RS12125	ENOG4105WH1	Two component transcriptional regulator luxr family
F0P95_RS12145	ENOG4107ZIC	Glycerol-3-phosphate cytidylyltransferase
F0P95_RS12175	ENOG4105VQ0	flagellar hook-basal body complex protein fliE
F0P95_RS12180	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
F0P95_RS12185	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
F0P95_RS12195	ENOG4108JIR	Flagellum-specific ATP synthase
F0P95_RS12215	ENOG4105D24	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
F0P95_RS12220	ENOG4105DD5	Flagellar motor switch protein
F0P95_RS12225	ENOG4105K0P	flagellar biosynthesis protein
F0P95_RS12230	ENOG4105CN7	Flagellar biosynthetic protein FliP
F0P95_RS12235	ENOG4105VS8	Flagellar biosynthetic protein fliq
F0P95_RS12240	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
F0P95_RS12245	ENOG4105BZU	Histidine kinase
F0P95_RS12250	ENOG4105D00	flagellar biosynthetic protein flhB
F0P95_RS12255	ENOG4105D7B	Flagellar biosynthesis protein flha
F0P95_RS12260	ENOG4105FZW	flagellar biosynthesis regulator FlhF
F0P95_RS12270	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
F0P95_RS12275	ENOG4108VYJ	response regulator receiver protein
F0P95_RS12290	ENOG4105E14	MotA TolQ exbB proton channel
F0P95_RS12295	ENOG4106VK6	Flagellar motor protein
F0P95_RS12315	ENOG4108VYJ	response regulator receiver protein
F0P95_RS12320	ENOG4105CBS	Chea signal transduction histidine kinase
F0P95_RS12330	ENOG4105C8Q	Methyl-accepting chemotaxis
F0P95_RS12335	ENOG4105C8Q	Methyl-accepting chemotaxis
F0P95_RS12340	ENOG4105C8Q	Methyl-accepting chemotaxis
F0P95_RS12345	ENOG4105C8Q	Methyl-accepting chemotaxis
F0P95_RS12350	ENOG4108REP	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Increasing levels of c-di-GMP lead to decreased motility (By similarity)
F0P95_RS12355	ENOG4108V3W	Chemotaxis protein, CheW
F0P95_RS12365	ENOG4105C8Q	Methyl-accepting chemotaxis
F0P95_RS12370	ENOG4105C8Q	Methyl-accepting chemotaxis
F0P95_RS12375	ENOG4105BZU	Histidine kinase
F0P95_RS12385	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
F0P95_RS12390	ENOG4105BZU	Histidine kinase
F0P95_RS12395	ENOG4105DFA	alanine racemase domain protein
F0P95_RS12480	ENOG4105BZU	Histidine kinase
F0P95_RS12495	ENOG4105CEY	Amp-dependent synthetase and ligase
F0P95_RS12500	ENOG4105E39	Enoyl-CoA hydratase
F0P95_RS12505	ENOG4105BZU	Histidine kinase
F0P95_RS12510	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
F0P95_RS12515	ENOG4105CRK	lysyL-tRNA synthetase
F0P95_RS12535	ENOG4105DY0	carbon monoxide dehydrogenase operon C protein
F0P95_RS12545	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
F0P95_RS12555	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
F0P95_RS12560	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
F0P95_RS12565	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
F0P95_RS12570	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
F0P95_RS12575	ENOG4105DYS	nad(p)h dehydrogenase (quinone)
F0P95_RS12585	ENOG4105CE1	Ferrous iron transport protein b
F0P95_RS12600	ENOG4105CBH	Hydroxymethylglutaryl-CoA lyase
F0P95_RS12615	ENOG4105FUQ	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
F0P95_RS12635	ENOG4105CQB	FAD linked oxidase domain protein
F0P95_RS12640	ENOG4108JQ1	Dehydrogenase
F0P95_RS12650	ENOG4105CUB	amino acid
F0P95_RS12655	ENOG4105CUB	amino acid
F0P95_RS12660	ENOG4107QY0	Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) (By similarity)
F0P95_RS12665	ENOG4108CAF	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway (By similarity)
F0P95_RS12670	ENOG4106YVY	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) (By similarity)
F0P95_RS12675	ENOG4108302	MgtC SapB transporter
F0P95_RS12690	ENOG4105D5Q	Arginine ornithine antiporter
F0P95_RS12740	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
F0P95_RS12745	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
F0P95_RS12750	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
F0P95_RS12755	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
F0P95_RS12760	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
F0P95_RS12765	ENOG4105CIH	Imidazole acetol-phosphate transaminase
F0P95_RS12770	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
F0P95_RS12775	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
F0P95_RS12785	ENOG4105CUT	histidyl-tRNA synthetase
F0P95_RS12790	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
F0P95_RS12800	ENOG4105D98	threonine synthase
F0P95_RS12830	ENOG4105C26	Dehydrogenase
F0P95_RS12845	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
F0P95_RS12850	ENOG4105D4A	Cell wall formation (By similarity)
F0P95_RS12860	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
F0P95_RS12865	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
F0P95_RS12875	ENOG4105D06	uba thif-type nad fad binding protein
F0P95_RS12880	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
F0P95_RS12885	ENOG4105CNE	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
F0P95_RS12895	ENOG4105HSZ	Cytoskeletal protein that is involved in cell-shape control through regulation of the length of the long axis (By similarity)
F0P95_RS12905	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
F0P95_RS12910	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
F0P95_RS12925	ENOG4105CHU	acetyl-coa acetyltransferase
F0P95_RS12930	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
F0P95_RS12940	ENOG4105ESV	Glycosyl transferase, family 4
F0P95_RS12945	ENOG4105CFV	Tetratricopeptide repeat protein
F0P95_RS12955	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
F0P95_RS12960	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
F0P95_RS12965	ENOG4105CAT	Cytidine monophosphate kinase
F0P95_RS12970	ENOG4105YK5	50S ribosomal protein L36
F0P95_RS12980	ENOG4105DWY	Agmatine deiminase
F0P95_RS13040	ENOG4107RUK	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins (By similarity)
F0P95_RS13045	ENOG41090A4	Pterin carbinolamine dehydratase
F0P95_RS13055	ENOG4105EI2	Pseudouridine synthase
F0P95_RS13060	ENOG4105C03	ribonuclease
F0P95_RS13065	ENOG4105WH1	Two component transcriptional regulator luxr family
F0P95_RS13070	ENOG410841Q	phosphoesterase PA-phosphatase related protein
F0P95_RS13075	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
F0P95_RS13085	ENOG4108UYB	regulatoR
F0P95_RS13090	ENOG4105H9W	Short-chain dehydrogenase reductase Sdr
F0P95_RS13095	ENOG4107QIJ	Aconitate hydratase 2
F0P95_RS13110	ENOG4107QM5	aconitate hydratase
F0P95_RS13120	ENOG4105CDU	Replicative dna helicase
F0P95_RS13130	ENOG4105CAQ	asparagine synthetase
F0P95_RS13135	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
F0P95_RS13140	ENOG4108TGY	Glutathione S-transferase
F0P95_RS13155	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
F0P95_RS13160	ENOG4108Z6B	deaminase
F0P95_RS13175	ENOG4105CC0	LysR family Transcriptional regulator
F0P95_RS13180	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
F0P95_RS13205	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
F0P95_RS13225	ENOG4107RGH	Aldehyde dehydrogenase
F0P95_RS13230	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
F0P95_RS13245	ENOG4108ZX5	transcriptional regulator
F0P95_RS13250	ENOG4107QP8	phosphohexose isomerase
F0P95_RS13255	ENOG4108Z2X	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity)
F0P95_RS13260	ENOG4108IAA	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
F0P95_RS13265	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
F0P95_RS13275	ENOG4105DJ0	Poly(A) Polymerase
F0P95_RS13285	ENOG4108Z4U	Ferredoxin
F0P95_RS13295	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
F0P95_RS13305	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
F0P95_RS13310	ENOG4108IAB	Phoh family
F0P95_RS13350	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
F0P95_RS13365	ENOG4105CAP	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P (By similarity)
F0P95_RS13375	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
F0P95_RS13380	ENOG4107NPY	receptor for the septal ring structure, may anchor it to the inner-membrane (By similarity)
F0P95_RS13395	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
F0P95_RS13400	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
F0P95_RS13405	ENOG4108Z4V	iron-sulfur cluster assembly
F0P95_RS13410	ENOG4105C5S	asparaginyl-tRNA synthetase
F0P95_RS13430	ENOG41077A9	carbonic anhydrase
F0P95_RS13445	ENOG4107RQD	Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid (By similarity)
F0P95_RS13450	ENOG4105CJB	Exodeoxyribonuclease I
F0P95_RS13500	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
F0P95_RS13505	ENOG4105C7I	Dehydrogenase
F0P95_RS13515	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
F0P95_RS13525	ENOG4105C1G	acyl-Coa dehydrogenase
F0P95_RS13530	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
F0P95_RS13535	ENOG4105C3R	Methionine synthase
F0P95_RS13540	ENOG4105C3R	Methionine synthase
F0P95_RS13550	ENOG4105EGI	Transcriptional regulator
F0P95_RS13555	ENOG4105CPN	adenine deaminase
F0P95_RS13560	ENOG4105D8G	Major Facilitator superfamily
F0P95_RS13575	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
F0P95_RS13580	ENOG4108V1T	peptidylprolyl cis-trans isomerase
F0P95_RS13595	ENOG410811P	TRANSCRIPTIONAl REGULATOR GntR family
F0P95_RS13600	ENOG4105CZV	ABC transporter
F0P95_RS13635	ENOG4107QTF	adenylosuccinate lyase
F0P95_RS13640	ENOG4105C8Q	Methyl-accepting chemotaxis
F0P95_RS13650	ENOG4105BZU	Histidine kinase
F0P95_RS13655	ENOG4105EZE	Cupin 4 family protein
F0P95_RS13665	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
F0P95_RS13670	ENOG4105C7S	Dehydrogenase
F0P95_RS13675	ENOG4107QN2	dihydrolipoyl dehydrogenase
F0P95_RS13680	ENOG4108URH	decarboxylase
F0P95_RS13685	ENOG4105BZU	Histidine kinase
F0P95_RS13690	ENOG4108MMM	RNA Polymerase
F0P95_RS13705	ENOG4105BZ1	(ABC) transporter
F0P95_RS13725	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
F0P95_RS13730	ENOG4105CFG	Acts as a chaperone (By similarity)
F0P95_RS13735	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
F0P95_RS13740	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
F0P95_RS13745	ENOG41090R7	Ferric uptake
F0P95_RS13750	ENOG4105YRI	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
F0P95_RS13765	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
F0P95_RS13790	ENOG4105E6M	Sulphatase-modifying factor protein
F0P95_RS13795	ENOG4108RVA	ribokinase
F0P95_RS13810	ENOG4105CXD	Specific inhibitor of chromosomal initiation of replication in vitro. Binds the three 13-mers in the origin (oriC) to block initiation of replication (By similarity)
F0P95_RS13815	ENOG4107RJ1	sodium solute
F0P95_RS13820	ENOG4105CI0	Citrate lyase
F0P95_RS13830	ENOG4105DFP	Integrase
F0P95_RS13865	ENOG4105KUS	lysozyme
F0P95_RS13885	ENOG4108ZUE	Phage regulatory protein rha
F0P95_RS13940	ENOG4105NI8	Cytosine-specific methyltransferase
F0P95_RS13965	ENOG4105D85	methylase
F0P95_RS13980	ENOG4105VM8	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity)
F0P95_RS13985	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
F0P95_RS13990	ENOG4105Y3E	Modulates RecA activity (By similarity)
F0P95_RS13995	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
F0P95_RS14010	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
F0P95_RS14015	ENOG4107TH8	cina domain protein
F0P95_RS14025	ENOG4105D7A	ATP-binding protein
F0P95_RS14040	ENOG4108RRZ	Transcription elongation factor GreB
F0P95_RS14050	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
F0P95_RS14070	ENOG4105DHP	deoxycytidine triphosphate deaminase
F0P95_RS14080	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
F0P95_RS14100	ENOG4105C9K	Endothelin-converting enzyme 1
F0P95_RS14115	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
F0P95_RS14120	ENOG4106UX7	integral membrane protein
F0P95_RS14135	ENOG4108YZY	peptidylprolyl cis-trans isomerase
F0P95_RS14140	ENOG4105K4H	Nlp p60 protein
F0P95_RS14145	ENOG4105K4H	Nlp p60 protein
F0P95_RS14160	ENOG4105CK2	sodium dicarboxylate symporter
F0P95_RS14170	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
F0P95_RS14175	ENOG41067QG	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
F0P95_RS14180	ENOG4105CTB	Polyprenyl synthetase
F0P95_RS14190	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
F0P95_RS14195	ENOG4105N42	UPF0307 protein
F0P95_RS14205	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
F0P95_RS14215	ENOG4105C03	ribonuclease
F0P95_RS14220	ENOG4108Z03	MAF-like protein
F0P95_RS14225	ENOG4105MPN	Membrane
F0P95_RS14235	ENOG4105D05	Receptor
F0P95_RS14245	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
F0P95_RS14255	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
F0P95_RS14270	ENOG4105C8T	Leucyl-tRNA synthetase
F0P95_RS14320	ENOG4108YZK	glyoxalase bleomycin resistance protein dioxygenase
F0P95_RS14325	ENOG4105CJ1	ABC, transporter
F0P95_RS14340	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
F0P95_RS14365	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
F0P95_RS14380	ENOG4105KHC	sulfurtransferase
F0P95_RS14385	ENOG4105P8F	nudix hydrolase
F0P95_RS14390	ENOG4108V1T	peptidylprolyl cis-trans isomerase
F0P95_RS14395	ENOG4105E39	Enoyl-CoA hydratase
F0P95_RS14405	ENOG4105CSM	endonuclease III
F0P95_RS14415	ENOG4107QMV	Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity)
F0P95_RS14420	ENOG4107QMV	Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity)
F0P95_RS14425	ENOG4105C8U	phosphate abc transporter
F0P95_RS14430	ENOG4105E2Z	phosphate ABC transporter (Permease
F0P95_RS14435	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
F0P95_RS14440	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
F0P95_RS14445	ENOG4105C2N	RNA methyltransferase TrmH family group 3
F0P95_RS14455	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
F0P95_RS14475	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
F0P95_RS14480	ENOG4105CW7	secretion protein, HlyD family
F0P95_RS14495	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
F0P95_RS14505	ENOG4105FQ6	thiopurine methyltransferase
F0P95_RS14510	ENOG4108UWD	Iron-storage protein
F0P95_RS14525	ENOG4105CAQ	asparagine synthetase
F0P95_RS14530	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
F0P95_RS14535	ENOG4105KUZ	arsenate reductase
F0P95_RS14550	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
F0P95_RS14555	ENOG4105CE9	30S ribosomal protein S2
F0P95_RS14560	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
F0P95_RS14565	ENOG4105BZU	Histidine kinase
F0P95_RS14570	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
F0P95_RS14585	ENOG4105KNE	Phosphatidate cytidylyltransferase
F0P95_RS14595	ENOG4105DZP	Membrane-associated zinc metalloprotease
F0P95_RS14600	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
F0P95_RS14605	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
F0P95_RS14615	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
F0P95_RS14620	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
F0P95_RS14625	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
F0P95_RS14635	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
F0P95_RS14640	ENOG4108YXA	Membrane
F0P95_RS14670	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
F0P95_RS14710	ENOG4108Z7R	Chaperone CsaA
F0P95_RS14755	ENOG4105BZ1	(ABC) transporter
F0P95_RS14760	ENOG4105FQP	Beta-lactamase
F0P95_RS14785	ENOG4105FE9	pseudouridine synthase
F0P95_RS14840	ENOG4105UGU	tonB-dependent Receptor
F0P95_RS14865	ENOG4105MYN	Zinc uptake regulation protein
F0P95_RS14870	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
F0P95_RS14880	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
F0P95_RS14885	ENOG4105C29	acyl-CoA thioesterase
F0P95_RS14895	ENOG4105GFR	rna polymerase sigma factor
F0P95_RS14905	ENOG4105DWA	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate
F0P95_RS14915	ENOG4108HH9	Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR
F0P95_RS14940	ENOG4105F6J	Alpha beta hydrolase fold
F0P95_RS14975	ENOG4105WH1	Two component transcriptional regulator luxr family
F0P95_RS14980	ENOG4105BZU	Histidine kinase
F0P95_RS14990	ENOG4105K7U	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
F0P95_RS14995	ENOG4107QMS	site-determining protein
F0P95_RS15000	ENOG4105VJP	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity)
F0P95_RS15010	ENOG4105EB3	Histidine kinase
F0P95_RS15015	ENOG4105ETX	regulatoR
F0P95_RS15020	ENOG4105SA9	Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity)
F0P95_RS15030	ENOG4105DIJ	Phosphoethanolamine transferase
F0P95_RS15055	ENOG4105DTA	methyltransferase
F0P95_RS15085	ENOG4105C2C	drug resistance transporter, Bcr CflA
F0P95_RS15090	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
F0P95_RS15105	ENOG4106AXJ	AraC family transcriptional regulator
F0P95_RS15120	ENOG41082F9	transcriptional regulator
F0P95_RS15160	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
F0P95_RS15170	ENOG4105EPW	hflc protein
F0P95_RS15175	ENOG4107QJR	hflk protein
F0P95_RS15185	ENOG4105M3Z	response regulator
F0P95_RS15210	ENOG4108JQB	penicillin-binding protein 1C
F0P95_RS15215	ENOG4105DN3	alpha-2-macroglobulin domain protein
F0P95_RS15220	ENOG4105C7F	AcnD-accessory protein PrpF
F0P95_RS15225	ENOG4108I0Z	Aconitate hydratase
F0P95_RS15230	ENOG4105BZN	citrate synthase
F0P95_RS15240	ENOG4105CR4	methylisocitrate lyase
F0P95_RS15245	ENOG4105BZN	citrate synthase
F0P95_RS15265	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
F0P95_RS15280	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
F0P95_RS15285	ENOG4105D49	3-dehydroquinate synthase
F0P95_RS15300	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
F0P95_RS15305	ENOG4105BZU	Histidine kinase
F0P95_RS15335	ENOG4105EJQ	L-serine dehydratase
F0P95_RS15340	ENOG4108KHX	Diguanylate cyclase
F0P95_RS15350	ENOG4105CFH	Aspartokinase
F0P95_RS15355	ENOG4105C28	cystathionine
F0P95_RS15360	ENOG4106TYC	homoserine o-acetyltransferase (EC 2.3.1.31)
F0P95_RS15365	ENOG4105DR5	peptidase
F0P95_RS15370	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
F0P95_RS15375	ENOG4108UT2	hemolysin iii
F0P95_RS15380	ENOG41066T0	asmA family
F0P95_RS15395	ENOG4108VKV	Monofunctional biosynthetic peptidoglycan transglycosylase
F0P95_RS15400	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
F0P95_RS15410	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
F0P95_RS15425	ENOG4107QPN	acyl-Coa dehydrogenase
F0P95_RS15525	ENOG4106NZI	LysR family Transcriptional regulator
F0P95_RS15530	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
F0P95_RS15535	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
F0P95_RS15540	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
F0P95_RS15545	ENOG4105C8Y	Acetylornithine aminotransferase
F0P95_RS15555	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
F0P95_RS15560	ENOG4105DFA	alanine racemase domain protein
F0P95_RS15565	ENOG4105DKK	Benzoate
F0P95_RS15590	ENOG4105K5X	acetyltransferase
F0P95_RS15605	ENOG4105XDF	Protein of unknown function (DUF1272)
F0P95_RS15610	ENOG4105MDH	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity)
F0P95_RS15730	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
F0P95_RS15735	ENOG4105C4R	Atp-dependent dna helicase
F0P95_RS15740	ENOG4105DFS	Conserved Protein
F0P95_RS15760	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
F0P95_RS15765	ENOG4105G5H	Membrane
F0P95_RS15770	ENOG4107QX8	SPFH domain, Band 7 family protein
F0P95_RS15780	ENOG4105KK4	UPF0060 membrane protein
F0P95_RS15785	ENOG4105DXN	mazG family
F0P95_RS15790	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
F0P95_RS15795	ENOG4107RK2	ADP-ribose diphosphatase NudE
F0P95_RS15800	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
F0P95_RS15810	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
F0P95_RS15815	ENOG4105CBS	Chea signal transduction histidine kinase
F0P95_RS15820	ENOG4105C8Q	Methyl-accepting chemotaxis
F0P95_RS15830	ENOG4105M3Z	response regulator
F0P95_RS15835	ENOG4108UNF	response regulator
F0P95_RS15840	ENOG4105D7Z	glutathione synthase
F0P95_RS15855	ENOG4107RNH	Outer membrane receptor FepA
F0P95_RS15860	ENOG4105CI2	imidazolone-5-propionate hydrolase
F0P95_RS15870	ENOG4108Z9K	Osmotically inducible protein
F0P95_RS15895	ENOG4105KPV	Transcriptional regulator
F0P95_RS15910	ENOG4105C3K	feS assembly ATPase SufC
F0P95_RS15915	ENOG4105JRK	feS assembly protein SufD
F0P95_RS15920	ENOG4105C9B	Cysteine desulfurase
F0P95_RS15930	ENOG4105VQD	rieske 2fe-2S domain-containing protein
F0P95_RS15935	ENOG4108ESX	Receptor
F0P95_RS15945	ENOG4107E2E	PKHD-type hydroxylase
F0P95_RS15955	ENOG4105D05	Receptor
F0P95_RS15975	ENOG4105CJ2	(LipO)protein
F0P95_RS15990	ENOG41090B9	response to stress
F0P95_RS15995	ENOG4106BE1	Participates in the degradation of poly-3- hydroxybutyrate (PHB). It works downstream of poly(3- hydroxybutyrate) depolymerase, hydrolyzing D(-)-3-hydroxybutyrate oligomers of various length (3HB-oligomers) into 3HB-monomers (By similarity)
F0P95_RS16030	ENOG41080HT	Transcriptional regulator, arsr family
F0P95_RS16045	ENOG4105BZU	Histidine kinase
F0P95_RS16055	ENOG4105CY2	Citrate transporter
F0P95_RS16060	ENOG41083P1	competence protein ComEA helix-hairpin-helix repeat protein
F0P95_RS16075	ENOG4105EHM	Aminoglycoside phosphotransferase
F0P95_RS16080	ENOG4108S0S	Nucleotidyl transferase
F0P95_RS16090	ENOG4105C02	permease
F0P95_RS16100	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
F0P95_RS16110	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
F0P95_RS16125	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
F0P95_RS16130	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
F0P95_RS16135	ENOG4107TUY	Histidine kinase
F0P95_RS16140	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
F0P95_RS16155	ENOG4107QHF	type ii secretion system protein e
F0P95_RS16160	ENOG4105CMR	udp-glucose 4-epimerase
F0P95_RS16180	ENOG4108KQJ	Type 11 methyltransferase
F0P95_RS16205	ENOG4105D7Q	type ii secretion system
F0P95_RS16210	ENOG4105EHH	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue (By similarity)
F0P95_RS16215	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
F0P95_RS16220	ENOG4105BZU	Histidine kinase
F0P95_RS16225	ENOG4105ETX	regulatoR
F0P95_RS16235	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
F0P95_RS16255	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
F0P95_RS16260	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
F0P95_RS16295	ENOG4105C4K	Nad synthetase
F0P95_RS16300	ENOG4105C2N	RNA methyltransferase TrmH family group 3
F0P95_RS16305	ENOG4105BZG	amino acid carrier protein
F0P95_RS16315	ENOG4105BZS	acriflavin resistance protein
F0P95_RS16320	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
F0P95_RS16325	ENOG4105C3T	may be the GTPase, regulating ATP sulfurylase activity (By similarity)
F0P95_RS16335	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
F0P95_RS16340	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
F0P95_RS16345	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
F0P95_RS16365	ENOG4107R11	Transcriptional regulator
F0P95_RS16370	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
F0P95_RS16380	ENOG4108UVJ	appr-1-p processing domain protein
F0P95_RS16385	ENOG4107R1Y	fructose-bisphosphate aldolase
F0P95_RS16390	ENOG4105CA9	Pyruvate kinase
F0P95_RS16400	ENOG4105BZA	Phosphoglycerate kinase
F0P95_RS16405	ENOG41068WN	
F0P95_RS16420	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
F0P95_RS16425	ENOG4105EIF	outer membrane protein W
F0P95_RS16450	ENOG4105CYC	Transferase
F0P95_RS16460	ENOG4105CV1	Transketolase (EC 2.2.1.1)
F0P95_RS16465	ENOG4105CK2	sodium dicarboxylate symporter
F0P95_RS16495	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
F0P95_RS16500	ENOG4105E4G	Type IV pilus
F0P95_RS16525	ENOG4108JQC	penicillin-binding protein 1A
F0P95_RS16535	ENOG4105BZN	citrate synthase
F0P95_RS16540	ENOG4105NRA	50s ribosomal protein l31 type b
F0P95_RS16545	ENOG4105DU0	nucleoside hydrolase
F0P95_RS16550	ENOG4105CB5	ATP-dependent DNA helicase recG
F0P95_RS16555	ENOG4105KME	endoribonuclease L-psp
F0P95_RS16560	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
F0P95_RS16565	ENOG4105VFG	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
F0P95_RS16580	ENOG4105DSJ	YicC domain protein
F0P95_RS16585	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
F0P95_RS16590	ENOG4108ZI4	Glyoxalase Bleomycin resistance protein (Dioxygenase
F0P95_RS16595	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
F0P95_RS16600	ENOG4105CSA	Coproporphyrinogen iii oxidase
F0P95_RS16615	ENOG4105D9Y	Splits dipeptides with a prolyl residue in the C- terminal position (By similarity)
F0P95_RS16620	ENOG4107RAQ	aminopeptidase
F0P95_RS16635	ENOG4105W8B	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division (By similarity)
F0P95_RS16645	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
F0P95_RS16680	ENOG41063JG	Transcriptional regulator
F0P95_RS16685	ENOG4105VCQ	rubredoxin
F0P95_RS16690	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
F0P95_RS16700	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
F0P95_RS16710	ENOG4105K59	histidine triad (HIT) protein
F0P95_RS16715	ENOG4105C8Y	Acetylornithine aminotransferase
F0P95_RS16720	ENOG4105EYW	Ion transport protein
F0P95_RS16740	ENOG410841Q	phosphoesterase PA-phosphatase related protein
F0P95_RS16750	ENOG4105DFU	Cell wall formation (By similarity)
F0P95_RS16755	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
F0P95_RS16770	ENOG4105EAY	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
F0P95_RS16775	ENOG4105F0N	pyrophosphate phospho-hydrolase
F0P95_RS16785	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
F0P95_RS16800	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
F0P95_RS16805	ENOG4105C94	Transporter
F0P95_RS16810	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
F0P95_RS16865	ENOG4105D7Q	type ii secretion system
F0P95_RS16900	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
F0P95_RS16915	ENOG4105C7B	Threonine dehydratase
F0P95_RS16920	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
F0P95_RS16935	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
F0P95_RS16940	ENOG4105D82	Glutamate dehydrogenase
F0P95_RS17020	ENOG4105C5Q	Transcriptional regulator
F0P95_RS17025	ENOG4105NXH	GreA GreB family elongation factor
F0P95_RS17055	ENOG4105CX6	glutaminyL-tRNA synthetase
F0P95_RS17065	ENOG4105EZ6	Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA (By similarity)
F0P95_RS17085	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
F0P95_RS17095	ENOG4105D0A	hydroxylase
F0P95_RS17105	ENOG4108WBT	adenosyltransferase
F0P95_RS17110	ENOG4105DGU	Histone deacetylase
F0P95_RS17115	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
F0P95_RS17120	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
F0P95_RS17125	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
F0P95_RS17130	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
F0P95_RS17135	ENOG4105NWN	ApaG protein
F0P95_RS17140	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
F0P95_RS17155	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
F0P95_RS17160	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
F0P95_RS17180	ENOG4105EE5	Membrane protein terC
F0P95_RS17185	ENOG41080IJ	Diacylglycerol kinase
F0P95_RS17190	ENOG4105DHQ	Histidine kinase
F0P95_RS17210	ENOG4107ENK	receptor
F0P95_RS17220	ENOG4105CPC	Aldo Keto reductase
F0P95_RS17225	ENOG4105D9N	nucleoside
F0P95_RS17235	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
F0P95_RS17260	ENOG4107KET	secretion protein, HlyD family
F0P95_RS17285	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
F0P95_RS17290	ENOG4108S4H	thioesterase Superfamily protein
F0P95_RS17295	ENOG4105D9P	serine threonine protein kinase
F0P95_RS17300	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
F0P95_RS17335	ENOG4105SYT	Methylenetetrahydrofolate reductase