locus-tag	class	description
F0P98_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
F0P98_RS00010	COG0592	DNA-directed DNA polymerase activity
F0P98_RS00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
F0P98_RS00020	COG0187	DNA topoisomerase II activity
F0P98_RS00030	COG0501	Belongs to the peptidase M48B family
F0P98_RS00070	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
F0P98_RS00080	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
F0P98_RS00095	COG4772	TonB-dependent receptor
F0P98_RS00105	COG0800	Aldolase
F0P98_RS00110	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
F0P98_RS00115	COG4771	TonB-dependent receptor
F0P98_RS00130	COG2272	Belongs to the type-B carboxylesterase lipase family
F0P98_RS00145	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
F0P98_RS00160	COG1609	Transcriptional regulator
F0P98_RS00165	COG1028	Short-chain dehydrogenase reductase Sdr
F0P98_RS00175	COG0302	gtp cyclohydrolase
F0P98_RS00180	COG3788	relative of glutathione S-transferase, MAPEG superfamily
F0P98_RS00185	COG4206	TonB-dependent receptor
F0P98_RS00205	COG1262	PFAM Formylglycine-generating sulfatase enzyme
F0P98_RS00210	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
F0P98_RS00215	COG0676	glucose-6-phosphate 1-epimerase activity
F0P98_RS00220	COG3135	benzoate transporter
F0P98_RS00255	COG1803	Methylglyoxal synthase
F0P98_RS00260	COG0493	'glutamate synthase
F0P98_RS00265	COG0070	glutamate synthase
F0P98_RS00265	COG0069	glutamate synthase activity
F0P98_RS00265	COG0067	glutamate synthase
F0P98_RS00300	COG1111	helicase
F0P98_RS00300	COG1205	dead DEAH box helicase
F0P98_RS00330	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
F0P98_RS00335	COG2885	chlorophyll binding
F0P98_RS00365	COG0714	Associated with various cellular activities
F0P98_RS00415	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
F0P98_RS00425	COG2062	phosphohistidine phosphatase, SixA
F0P98_RS00435	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
F0P98_RS00455	COG2202	Pas domain
F0P98_RS00455	COG2200	EAL domain
F0P98_RS00455	COG2199	diguanylate cyclase activity
F0P98_RS00485	COG1968	undecaprenyl-diphosphatase activity
F0P98_RS00490	COG0174	glutamine synthetase
F0P98_RS00500	COG0004	ammonium transporteR
F0P98_RS00505	COG3852	Histidine kinase
F0P98_RS00510	COG2204	response regulator
F0P98_RS00515	COG2815	serine threonine protein kinase
F0P98_RS00515	COG0515	serine threonine protein kinase
F0P98_RS00520	COG2032	superoxide dismutase activity
F0P98_RS00525	COG2032	superoxide dismutase activity
F0P98_RS00535	COG0183	Belongs to the thiolase family
F0P98_RS00585	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
F0P98_RS00590	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
F0P98_RS00620	COG1028	Short-chain dehydrogenase reductase Sdr
F0P98_RS00640	COG3474	cytochrome
F0P98_RS00655	COG0454	-acetyltransferase
F0P98_RS00715	COG0129	dihydroxy-acid dehydratase activity
F0P98_RS00725	COG0754	glutathionylspermidine amidase activity
F0P98_RS00740	COG0714	Associated with various cellular activities
F0P98_RS00770	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
F0P98_RS00850	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
F0P98_RS00855	COG1040	competence protein
F0P98_RS00865	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
F0P98_RS00875	COG2207	Transcriptional regulator
F0P98_RS00885	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
F0P98_RS00935	COG0606	chelatase, subunit chli
F0P98_RS00940	COG2960	long-chain fatty acid transporting porin activity
F0P98_RS00965	COG1166	arginine decarboxylase activity
F0P98_RS00970	COG4221	oxidoreductase activity
F0P98_RS00980	COG0018	arginyl-trna synthetase
F0P98_RS00990	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
F0P98_RS01010	COG2205	protein histidine kinase activity
F0P98_RS01020	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
F0P98_RS01025	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
F0P98_RS01035	COG3621	Patatin-like phospholipase
F0P98_RS01050	COG2948	multi-organism process
F0P98_RS01065	COG3846	protein secretion by the type IV secretion system
F0P98_RS01120	COG2003	Belongs to the UPF0758 family
F0P98_RS01125	COG4804	nuclease activity
F0P98_RS01145	COG0708	Exodeoxyribonuclease III
F0P98_RS01150	COG2223	nitrite transmembrane transporter activity
F0P98_RS01165	COG0739	heme binding
F0P98_RS01170	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
F0P98_RS01210	COG4942	peptidase
F0P98_RS01215	COG0793	Belongs to the peptidase S41A family
F0P98_RS01250	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
F0P98_RS01250	COG1565	acr, cog1565
F0P98_RS01255	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
F0P98_RS01260	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
F0P98_RS01305	COG0358	DNA primase activity
F0P98_RS01310	COG1295	ribonuclease BN
F0P98_RS01315	COG1610	YqeY-like protein
F0P98_RS01325	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
F0P98_RS01330	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
F0P98_RS01335	COG0668	transmembrane transport
F0P98_RS01350	COG2133	pyrroloquinoline quinone binding
F0P98_RS01355	COG1301	dicarboxylic acid transport
F0P98_RS01365	COG1737	Transcriptional regulator
F0P98_RS01370	COG4948	Mandelate Racemase Muconate Lactonizing
F0P98_RS01390	COG0019	diaminopimelate decarboxylase activity
F0P98_RS01395	COG3023	N-Acetylmuramoyl-L-alanine amidase
F0P98_RS01410	COG3023	N-Acetylmuramoyl-L-alanine amidase
F0P98_RS01415	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
F0P98_RS01420	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
F0P98_RS01445	COG5383	Protein conserved in bacteria
F0P98_RS01455	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
F0P98_RS01460	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
F0P98_RS01465	COG1473	amidohydrolase
F0P98_RS01470	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
F0P98_RS01470	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
F0P98_RS01475	COG1652	LysM domain
F0P98_RS01500	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
F0P98_RS01505	COG3118	belongs to the thioredoxin family
F0P98_RS01515	COG2884	Cell division ATP-binding protein ftsE
F0P98_RS01520	COG2177	Part of the ABC transporter FtsEX involved in
F0P98_RS01525	COG2201	protein-glutamate methylesterase activity
F0P98_RS01530	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
F0P98_RS01535	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
F0P98_RS01545	COG1252	NADH dehydrogenase
F0P98_RS01555	COG0625	glutathione transferase activity
F0P98_RS01565	COG3537	Alpha-1,2-mannosidase
F0P98_RS01580	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
F0P98_RS01590	COG3250	beta-galactosidase activity
F0P98_RS01610	COG4585	Histidine kinase
F0P98_RS01620	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
F0P98_RS01635	COG0534	Mate efflux family protein
F0P98_RS01640	COG0616	signal peptide processing
F0P98_RS01650	COG1028	Short-chain dehydrogenase reductase Sdr
F0P98_RS01660	COG0745	RESPONSE REGULATOR receiver
F0P98_RS01675	COG0009	L-threonylcarbamoyladenylate synthase
F0P98_RS01680	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
F0P98_RS01680	COG1754	DNA topoisomerase type I activity
F0P98_RS01685	COG1714	RDD family
F0P98_RS01695	COG2922	Belongs to the Smg family
F0P98_RS01700	COG0758	DNA mediated transformation
F0P98_RS01710	COG0242	peptide deformylase activity
F0P98_RS01715	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
F0P98_RS01720	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
F0P98_RS01720	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
F0P98_RS01730	COG1215	transferase activity, transferring glycosyl groups
F0P98_RS01765	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
F0P98_RS01775	COG1490	D-aminoacyl-tRNA deacylase activity
F0P98_RS01780	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
F0P98_RS01785	COG3537	Alpha-1,2-mannosidase
F0P98_RS01795	COG0582	viral genome integration into host DNA
F0P98_RS01800	COG1309	transcriptional regulator
F0P98_RS01815	COG1764	response to oxidative stress
F0P98_RS01830	COG4716	Myosin-crossreactive antigen
F0P98_RS01835	COG1250	3-hydroxyacyl-CoA dehydrogenase
F0P98_RS01875	COG2197	response regulator
F0P98_RS01880	COG2205	protein histidine kinase activity
F0P98_RS01880	COG0784	Response regulator, receiver
F0P98_RS01890	COG0784	Response regulator, receiver
F0P98_RS01890	COG2205	protein histidine kinase activity
F0P98_RS01895	COG1506	peptidase
F0P98_RS01900	COG3655	Transcriptional regulator
F0P98_RS01915	COG4774	siderophore transport
F0P98_RS01920	COG5001	Diguanylate cyclase
F0P98_RS01920	COG4251	negative regulation of phosphorylation
F0P98_RS01920	COG3706	GGDEF domain
F0P98_RS01920	COG2203	Gaf domain
F0P98_RS01930	COG3038	cytochrome b561
F0P98_RS01975	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
F0P98_RS02000	COG3237	CsbD-like
F0P98_RS02010	COG0180	Tryptophanyl-tRNA synthetase
F0P98_RS02030	COG0697	spore germination
F0P98_RS02035	COG2962	Rard protein
F0P98_RS02045	COG4206	TonB-dependent receptor
F0P98_RS02050	COG1136	(ABC) transporter
F0P98_RS02050	COG0577	efflux transmembrane transporter activity
F0P98_RS02060	COG1136	(ABC) transporter
F0P98_RS02065	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
F0P98_RS02070	COG1131	(ABC) transporter
F0P98_RS02075	COG0842	Transport permease protein
F0P98_RS02080	COG4585	Histidine kinase
F0P98_RS02085	COG2197	response regulator
F0P98_RS02095	COG0753	catalase activity
F0P98_RS02100	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
F0P98_RS02110	COG0628	permease
F0P98_RS02130	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
F0P98_RS02220	COG0789	Transcriptional regulator
F0P98_RS02230	COG4807	Protein conserved in bacteria
F0P98_RS02245	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
F0P98_RS02260	COG3264	Mechanosensitive ion channel
F0P98_RS02260	COG1196	nuclear chromosome segregation
F0P98_RS02265	COG1368	sulfuric ester hydrolase activity
F0P98_RS02270	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
F0P98_RS02275	COG2354	Protein conserved in bacteria
F0P98_RS02290	COG0612	Peptidase, M16
F0P98_RS02295	COG3706	GGDEF domain
F0P98_RS02300	COG0702	epimerase
F0P98_RS02325	COG0508	dehydrogenase complex catalyzes the overall conversion of
F0P98_RS02340	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
F0P98_RS02345	COG3483	tryptophan 2,3-dioxygenase activity
F0P98_RS02350	COG3104	oligopeptide transport
F0P98_RS02385	COG1320	monovalent cation:proton antiporter activity
F0P98_RS02390	COG2212	antiporter activity
F0P98_RS02400	COG0651	ATP synthesis coupled electron transport
F0P98_RS02405	COG1006	Multisubunit Na H antiporter MnhC subunit
F0P98_RS02410	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
F0P98_RS02410	COG2111	Na H antiporter
F0P98_RS02425	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
F0P98_RS02430	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
F0P98_RS02435	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
F0P98_RS02460	COG2205	protein histidine kinase activity
F0P98_RS02485	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
F0P98_RS02490	COG0134	indole-3-glycerol-phosphate synthase activity
F0P98_RS02500	COG0730	response to heat
F0P98_RS02505	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
F0P98_RS02510	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
F0P98_RS02520	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
F0P98_RS02525	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
F0P98_RS02530	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
F0P98_RS02550	COG1051	belongs to the nudix hydrolase family
F0P98_RS02565	COG5002	protein histidine kinase activity
F0P98_RS02565	COG2205	protein histidine kinase activity
F0P98_RS02565	COG0784	Response regulator, receiver
F0P98_RS02620	COG2814	Major facilitator Superfamily
F0P98_RS02630	COG2814	Major facilitator Superfamily
F0P98_RS02635	COG1289	transmembrane transporter activity
F0P98_RS02645	COG0667	Aldo Keto reductase
F0P98_RS02650	COG0151	Belongs to the GarS family
F0P98_RS02665	COG0138	bifunctional purine biosynthesis protein purh
F0P98_RS02670	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
F0P98_RS02680	COG2264	protein methyltransferase activity
F0P98_RS02685	COG0439	Biotin carboxylase
F0P98_RS02690	COG0511	ligase activity, forming carbon-carbon bonds
F0P98_RS02695	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
F0P98_RS02700	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
F0P98_RS02710	COG1324	tolerance protein
F0P98_RS02715	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
F0P98_RS02720	COG0459	protein refolding
F0P98_RS02730	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
F0P98_RS02765	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
F0P98_RS02810	COG2375	cellular response to nickel ion
F0P98_RS02865	COG4771	TonB-dependent receptor
F0P98_RS02895	COG3214	Protein conserved in bacteria
F0P98_RS02910	COG0024	Methionine aminopeptidase
F0P98_RS02925	COG3218	ABC-type transport auxiliary lipoprotein component
F0P98_RS02925	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
F0P98_RS02930	COG1127	ABC transporter
F0P98_RS02935	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
F0P98_RS02950	COG0442	prolyl-tRNA aminoacylation
F0P98_RS02960	COG1183	phosphatidylcholine synthase activity
F0P98_RS02970	COG0456	acetyltransferase
F0P98_RS02980	COG0525	valine-tRNA ligase activity
F0P98_RS02995	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
F0P98_RS03005	COG0795	lipopolysaccharide-transporting ATPase activity
F0P98_RS03015	COG4974	Belongs to the 'phage' integrase family
F0P98_RS03020	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
F0P98_RS03030	COG0047	phosphoribosylformylglycinamidine synthase activity
F0P98_RS03030	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
F0P98_RS03055	COG1215	transferase activity, transferring glycosyl groups
F0P98_RS03060	COG1215	transferase activity, transferring glycosyl groups
F0P98_RS03065	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
F0P98_RS03070	COG0457	Tetratricopeptide repeat
F0P98_RS03075	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
F0P98_RS03090	COG2194	sulfuric ester hydrolase activity
F0P98_RS03105	COG1215	transferase activity, transferring glycosyl groups
F0P98_RS03110	COG1215	transferase activity, transferring glycosyl groups
F0P98_RS03115	COG3118	belongs to the thioredoxin family
F0P98_RS03115	COG0457	Tetratricopeptide repeat
F0P98_RS03120	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
F0P98_RS03130	COG2252	PERMEase
F0P98_RS03135	COG0488	(ABC) transporter
F0P98_RS03145	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
F0P98_RS03150	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
F0P98_RS03160	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
F0P98_RS03160	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
F0P98_RS03175	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
F0P98_RS03180	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
F0P98_RS03190	COG0277	FAD linked oxidase domain protein
F0P98_RS03195	COG1988	membrane-bound metal-dependent
F0P98_RS03200	COG0792	nuclease activity
F0P98_RS03225	COG2001	Belongs to the MraZ family
F0P98_RS03230	COG0275	rRNA processing
F0P98_RS03235	COG3116	cell division
F0P98_RS03250	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
F0P98_RS03275	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
F0P98_RS03285	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
F0P98_RS03290	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
F0P98_RS03300	COG0739	heme binding
F0P98_RS03305	COG0653	protein targeting
F0P98_RS03310	COG0494	nUDIX hydrolase
F0P98_RS03320	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
F0P98_RS03335	COG0456	acetyltransferase
F0P98_RS03345	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
F0P98_RS03355	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
F0P98_RS03360	COG2815	serine threonine protein kinase
F0P98_RS03360	COG0515	serine threonine protein kinase
F0P98_RS03365	COG1607	acyl-coa hydrolase
F0P98_RS03370	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
F0P98_RS03390	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
F0P98_RS03415	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
F0P98_RS03425	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
F0P98_RS03430	COG0667	Aldo Keto reductase
F0P98_RS03440	COG4771	TonB-dependent receptor
F0P98_RS03460	COG0642	Histidine kinase
F0P98_RS03465	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
F0P98_RS03470	COG0861	Integral membrane protein TerC family
F0P98_RS03490	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
F0P98_RS03495	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
F0P98_RS03510	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
F0P98_RS03515	COG2967	ApaG domain
F0P98_RS03520	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
F0P98_RS03525	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
F0P98_RS03530	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
F0P98_RS03535	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
F0P98_RS03545	COG2096	Adenosyltransferase
F0P98_RS03555	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
F0P98_RS03560	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
F0P98_RS03565	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
F0P98_RS03585	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
F0P98_RS03595	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
F0P98_RS03610	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
F0P98_RS03625	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
F0P98_RS03630	COG0583	DNA-binding transcription factor activity
F0P98_RS03640	COG3634	alkyl hydroperoxide reductase activity
F0P98_RS03670	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
F0P98_RS03695	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
F0P98_RS03700	COG0473	3-isopropylmalate dehydrogenase activity
F0P98_RS03715	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
F0P98_RS03735	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
F0P98_RS03780	COG3267	Type II secretory pathway component ExeA
F0P98_RS03780	COG3409	Peptidoglycan-binding domain 1 protein
F0P98_RS03825	COG0405	Gamma-glutamyltransferase
F0P98_RS03830	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
F0P98_RS03835	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
F0P98_RS03860	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
F0P98_RS03865	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
F0P98_RS03890	COG0563	adenylate kinase activity
F0P98_RS03895	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
F0P98_RS03905	COG0671	phosphoesterase, PA-phosphatase related
F0P98_RS03920	COG1028	Short-chain dehydrogenase reductase Sdr
F0P98_RS03925	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
F0P98_RS03930	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
F0P98_RS03935	COG0537	adenosine 5'-monophosphoramidase activity
F0P98_RS03945	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
F0P98_RS03955	COG0352	thiamine-phosphate diphosphorylase activity
F0P98_RS03965	COG2912	Transglutaminase-like superfamily
F0P98_RS04000	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
F0P98_RS04020	COG3079	Belongs to the UPF0149 family
F0P98_RS04025	COG0006	proline dipeptidase activity
F0P98_RS04030	COG0006	proline dipeptidase activity
F0P98_RS04045	COG0635	Involved in the biosynthesis of porphyrin-containing compound
F0P98_RS04055	COG0346	lactoylglutathione lyase activity
F0P98_RS04060	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
F0P98_RS04065	COG1561	YicC-like family, N-terminal region
F0P98_RS04080	COG1758	RNA polymerase activity
F0P98_RS04085	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
F0P98_RS04095	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
F0P98_RS04105	COG0254	rRNA binding
F0P98_RS04150	COG0714	Associated with various cellular activities
F0P98_RS04180	COG1301	dicarboxylic acid transport
F0P98_RS04185	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
F0P98_RS04200	COG0427	acetyl-CoA hydrolase
F0P98_RS04230	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
F0P98_RS04245	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
F0P98_RS04250	COG0126	phosphoglycerate kinase activity
F0P98_RS04260	COG0469	pyruvate kinase activity
F0P98_RS04265	COG3588	fructose-bisphosphate aldolase
F0P98_RS04270	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
F0P98_RS04285	COG0583	DNA-binding transcription factor activity
F0P98_RS04305	COG0175	sulfate reduction
F0P98_RS04310	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
F0P98_RS04315	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
F0P98_RS04325	COG2895	sulfate adenylyltransferase (ATP) activity
F0P98_RS04325	COG0529	Catalyzes the synthesis of activated sulfate
F0P98_RS04330	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
F0P98_RS04335	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
F0P98_RS04345	COG1115	amino acid carrier protein
F0P98_RS04350	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
F0P98_RS04355	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
F0P98_RS04355	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
F0P98_RS04385	COG3273	potassium ion transport
F0P98_RS04385	COG0471	metal ion transport
F0P98_RS04395	COG2022	thiamine diphosphate biosynthetic process
F0P98_RS04415	COG0189	ligase activity
F0P98_RS04425	COG0745	RESPONSE REGULATOR receiver
F0P98_RS04440	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
F0P98_RS04445	COG1459	type II secretion system
F0P98_RS04465	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
F0P98_RS04480	COG0673	inositol 2-dehydrogenase activity
F0P98_RS04485	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
F0P98_RS04505	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
F0P98_RS04515	COG5001	Diguanylate cyclase
F0P98_RS04520	COG4191	Histidine kinase
F0P98_RS04535	COG0045	succinate-CoA ligase (ADP-forming) activity
F0P98_RS04540	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
F0P98_RS04555	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
F0P98_RS04570	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
F0P98_RS04580	COG0628	permease
F0P98_RS04590	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
F0P98_RS04610	COG1555	photosystem II stabilization
F0P98_RS04615	COG2610	gluconate transmembrane transporter activity
F0P98_RS04620	COG4771	TonB-dependent receptor
F0P98_RS04625	COG2205	protein histidine kinase activity
F0P98_RS04640	COG0640	Transcriptional regulator
F0P98_RS04670	COG1028	Short-chain dehydrogenase reductase Sdr
F0P98_RS04690	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
F0P98_RS04695	COG1477	protein flavinylation
F0P98_RS04715	COG4771	TonB-dependent receptor
F0P98_RS04725	COG3128	pkhd-type hydroxylase
F0P98_RS04735	COG4774	siderophore transport
F0P98_RS04740	COG2146	nitrite reductase [NAD(P)H] activity
F0P98_RS04750	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
F0P98_RS04755	COG0719	Fe-S assembly protein
F0P98_RS04760	COG0396	ATPase activity
F0P98_RS04770	COG0719	Fe-S assembly protein
F0P98_RS04775	COG1959	2 iron, 2 sulfur cluster binding
F0P98_RS04800	COG1764	response to oxidative stress
F0P98_RS04830	COG0189	ligase activity
F0P98_RS04845	COG0835	chemotaxis
F0P98_RS04850	COG0840	transmembrane signaling receptor activity
F0P98_RS04870	COG1385	rRNA (uridine-N3-)-methyltransferase activity
F0P98_RS04875	COG0494	nUDIX hydrolase
F0P98_RS04880	COG1218	3'(2'),5'-bisphosphate nucleotidase
F0P98_RS04885	COG3956	TIGRFAM MazG family protein
F0P98_RS04890	COG1742	UPF0060 membrane protein
F0P98_RS04900	COG0330	HflC and HflK could
F0P98_RS04910	COG0404	The glycine cleavage system catalyzes the degradation of glycine
F0P98_RS04955	COG1960	acyl-CoA dehydrogenase activity
F0P98_RS04980	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
F0P98_RS04985	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
F0P98_RS04990	COG0463	Glycosyl transferase, family 2
F0P98_RS04995	COG0617	tRNA 3'-terminal CCA addition
F0P98_RS04995	COG3620	sequence-specific DNA binding
F0P98_RS04995	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
F0P98_RS05000	COG2982	Protein involved in outer membrane biogenesis
F0P98_RS05005	COG1272	protein, Hemolysin III
F0P98_RS05010	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
F0P98_RS05015	COG0739	heme binding
F0P98_RS05020	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
F0P98_RS05025	COG0626	cystathionine gamma-synthase activity
F0P98_RS05030	COG0460	homoserine dehydrogenase
F0P98_RS05030	COG0527	aspartate kinase activity
F0P98_RS05040	COG2199	diguanylate cyclase activity
F0P98_RS05045	COG1760	l-serine dehydratase
F0P98_RS05065	COG3038	cytochrome b561
F0P98_RS05080	COG2814	Major facilitator Superfamily
F0P98_RS05100	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
F0P98_RS05135	COG0372	Belongs to the citrate synthase family
F0P98_RS05165	COG2373	Large extracellular alpha-helical protein
F0P98_RS05170	COG4953	penicillin-binding protein 1C
F0P98_RS05180	COG0678	peroxiredoxin activity
F0P98_RS05200	COG0604	alcohol dehydrogenase
F0P98_RS05205	COG0330	HflC and HflK could
F0P98_RS05210	COG0330	HflC and HflK could
F0P98_RS05220	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
F0P98_RS05225	COG2801	Transposase and inactivated derivatives
F0P98_RS05260	COG1846	Transcriptional regulator
F0P98_RS05275	COG1917	Cupin 2, conserved barrel domain protein
F0P98_RS05275	COG2207	Transcriptional regulator
F0P98_RS05290	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
F0P98_RS05290	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
F0P98_RS05295	COG2814	Major facilitator Superfamily
F0P98_RS05325	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
F0P98_RS05355	COG2194	sulfuric ester hydrolase activity
F0P98_RS05365	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
F0P98_RS05375	COG2205	protein histidine kinase activity
F0P98_RS05385	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
F0P98_RS05390	COG2894	cell division
F0P98_RS05395	COG0850	regulation of cytokinetic process
F0P98_RS05405	COG4585	Histidine kinase
F0P98_RS05410	COG2197	response regulator
F0P98_RS05425	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
F0P98_RS05440	COG1073	alpha beta
F0P98_RS05465	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
F0P98_RS05475	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
F0P98_RS05485	COG1595	DNA-templated transcription, initiation
F0P98_RS05495	COG1946	Acyl-CoA thioesterase
F0P98_RS05500	COG1024	Enoyl-CoA hydratase
F0P98_RS05500	COG1250	3-hydroxyacyl-CoA dehydrogenase
F0P98_RS05510	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
F0P98_RS05515	COG0735	belongs to the Fur family
F0P98_RS05600	COG1187	pseudouridine synthase activity
F0P98_RS05625	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
F0P98_RS05635	COG1132	(ABC) transporter
F0P98_RS05680	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
F0P98_RS05750	COG0825	malonyl-CoA metabolic process
F0P98_RS05770	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
F0P98_RS05780	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
F0P98_RS05785	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
F0P98_RS05790	COG0750	zinc metalloprotease
F0P98_RS05795	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
F0P98_RS05800	COG0575	Belongs to the CDS family
F0P98_RS05810	COG0233	cytoplasmic translational termination
F0P98_RS05815	COG0528	UMP kinase activity
F0P98_RS05820	COG3706	GGDEF domain
F0P98_RS05825	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
F0P98_RS05830	COG0052	Belongs to the universal ribosomal protein uS2 family
F0P98_RS05835	COG0024	Methionine aminopeptidase
F0P98_RS05840	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
F0P98_RS05850	COG1393	Belongs to the ArsC family
F0P98_RS05855	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
F0P98_RS05860	COG0367	asparagine synthase
F0P98_RS05905	COG1566	PFAM secretion protein HlyD family protein
F0P98_RS05910	COG2814	Major facilitator Superfamily
F0P98_RS05930	COG0557	exoribonuclease II activity
F0P98_RS05935	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
F0P98_RS05940	COG0704	Plays a role in the regulation of phosphate uptake
F0P98_RS05950	COG0581	inorganic phosphate transmembrane transporter activity
F0P98_RS05955	COG0573	inorganic phosphate transmembrane transporter activity
F0P98_RS05960	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
F0P98_RS05965	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
F0P98_RS05990	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
F0P98_RS06000	COG1024	Enoyl-CoA hydratase
F0P98_RS06010	COG0494	nUDIX hydrolase
F0P98_RS06030	COG0116	Belongs to the methyltransferase superfamily
F0P98_RS06030	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
F0P98_RS06055	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
F0P98_RS06055	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
F0P98_RS06070	COG1131	(ABC) transporter
F0P98_RS06075	COG0346	lactoylglutathione lyase activity
F0P98_RS06100	COG2203	Gaf domain
F0P98_RS06100	COG4251	negative regulation of phosphorylation
F0P98_RS06100	COG3706	GGDEF domain
F0P98_RS06100	COG5001	Diguanylate cyclase
F0P98_RS06135	COG0495	leucyl-tRNA aminoacylation
F0P98_RS06150	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
F0P98_RS06160	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
F0P98_RS06180	COG2968	Membrane
F0P98_RS06185	COG0424	maF-like protein
F0P98_RS06190	COG1530	ribonuclease E activity
F0P98_RS06200	COG0312	modulator of DNA gyrase
F0P98_RS06215	COG3028	Belongs to the UPF0307 family
F0P98_RS06220	COG0312	modulator of DNA gyrase
F0P98_RS06230	COG0142	geranyltranstransferase activity
F0P98_RS06235	COG1722	exodeoxyribonuclease VII activity
F0P98_RS06240	COG0037	tRNA processing
F0P98_RS06250	COG1301	dicarboxylic acid transport
F0P98_RS06255	COG0612	Peptidase, M16
F0P98_RS06260	COG0612	Peptidase, M16
F0P98_RS06265	COG0791	NLP P60 protein
F0P98_RS06270	COG0791	NLP P60 protein
F0P98_RS06275	COG1047	Peptidyl-prolyl cis-trans
F0P98_RS06280	COG2311	Membrane
F0P98_RS06290	COG0697	spore germination
F0P98_RS06310	COG3590	peptidase
F0P98_RS06320	COG0457	Tetratricopeptide repeat
F0P98_RS06325	COG4771	TonB-dependent receptor
F0P98_RS06330	COG0489	protein tyrosine kinase activity
F0P98_RS06335	COG0717	Belongs to the dCTP deaminase family
F0P98_RS06350	COG0412	Dienelactone hydrolase
F0P98_RS06355	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
F0P98_RS06365	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
F0P98_RS06370	COG0433	COG0433 Predicted ATPase
F0P98_RS06380	COG1546	Belongs to the CinA family
F0P98_RS06385	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
F0P98_RS06395	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
F0P98_RS06400	COG2137	regulation of response to DNA damage stimulus
F0P98_RS06405	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
F0P98_RS06410	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
F0P98_RS06430	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
F0P98_RS06435	COG0583	DNA-binding transcription factor activity
F0P98_RS06450	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
F0P98_RS06455	COG1262	PFAM Formylglycine-generating sulfatase enzyme
F0P98_RS06480	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
F0P98_RS06495	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
F0P98_RS06505	COG0497	DNA recombination
F0P98_RS06510	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
F0P98_RS06515	COG0443	Heat shock 70 kDa protein
F0P98_RS06520	COG0484	heat shock protein binding
F0P98_RS06525	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
F0P98_RS06540	COG1132	(ABC) transporter
F0P98_RS06555	COG1595	DNA-templated transcription, initiation
F0P98_RS06570	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
F0P98_RS06580	COG0567	Dehydrogenase, E1 component
F0P98_RS06590	COG2850	peptidyl-arginine hydroxylation
F0P98_RS06605	COG0840	transmembrane signaling receptor activity
F0P98_RS06640	COG1131	(ABC) transporter
F0P98_RS06645	COG1725	Transcriptional regulator
F0P98_RS06655	COG0386	Belongs to the glutathione peroxidase family
F0P98_RS06670	COG2900	Belongs to the SlyX family
F0P98_RS06680	COG2814	Major facilitator Superfamily
F0P98_RS06685	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
F0P98_RS06690	COG0583	DNA-binding transcription factor activity
F0P98_RS06710	COG2226	methyltransferase
F0P98_RS06715	COG1960	acyl-CoA dehydrogenase activity
F0P98_RS06725	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
F0P98_RS06730	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
F0P98_RS06740	COG2902	Dehydrogenase
F0P98_RS06760	COG1278	Cold shock
F0P98_RS06795	COG2925	Exonuclease
F0P98_RS06800	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
F0P98_RS06805	COG3844	kynureninase activity
F0P98_RS06815	COG0288	reversible hydration of carbon dioxide
F0P98_RS06820	COG2808	Putative FMN-binding domain
F0P98_RS06835	COG0017	Asparaginyl-tRNA synthetase
F0P98_RS06840	COG0316	Belongs to the HesB IscA family
F0P98_RS06845	COG0360	Binds together with S18 to 16S ribosomal RNA
F0P98_RS06850	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
F0P98_RS06870	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
F0P98_RS06915	COG0351	phosphomethylpyrimidine kinase
F0P98_RS06915	COG0352	thiamine-phosphate diphosphorylase activity
F0P98_RS06935	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
F0P98_RS06940	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
F0P98_RS06950	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
F0P98_RS06960	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
F0P98_RS06970	COG0617	tRNA 3'-terminal CCA addition
F0P98_RS06980	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
F0P98_RS06985	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
F0P98_RS06990	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
F0P98_RS06995	COG0166	Belongs to the GPI family
F0P98_RS07040	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
F0P98_RS07045	COG1605	Chorismate mutase
F0P98_RS07045	COG0077	Prephenate dehydratase
F0P98_RS07050	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
F0P98_RS07065	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
F0P98_RS07070	COG0583	DNA-binding transcription factor activity
F0P98_RS07090	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
F0P98_RS07105	COG0625	glutathione transferase activity
F0P98_RS07110	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
F0P98_RS07115	COG0367	asparagine synthase
F0P98_RS07125	COG0305	Participates in initiation and elongation during chromosome replication
F0P98_RS07155	COG1028	Short-chain dehydrogenase reductase Sdr
F0P98_RS07160	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
F0P98_RS07170	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
F0P98_RS07175	COG0671	phosphoesterase, PA-phosphatase related
F0P98_RS07185	COG1530	ribonuclease E activity
F0P98_RS07200	COG2154	pterin-4-alpha-carbinolamine dehydratase
F0P98_RS07205	COG0316	Belongs to the HesB IscA family
F0P98_RS07205	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
F0P98_RS07235	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
F0P98_RS07260	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
F0P98_RS07265	COG2957	Belongs to the agmatine deiminase family
F0P98_RS07275	COG0257	Belongs to the bacterial ribosomal protein bL36 family
F0P98_RS07280	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
F0P98_RS07290	COG0776	regulation of translation
F0P98_RS07300	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
F0P98_RS07320	COG0183	Belongs to the thiolase family
F0P98_RS07325	COG1250	3-hydroxyacyl-CoA dehydrogenase
F0P98_RS07325	COG1024	Enoyl-CoA hydratase
F0P98_RS07335	COG0105	UTP biosynthetic process
F0P98_RS07340	COG0820	rRNA (adenine-C2-)-methyltransferase activity
F0P98_RS07350	COG1426	Protein conserved in bacteria
F0P98_RS07360	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
F0P98_RS07365	COG1160	GTP binding
F0P98_RS07370	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
F0P98_RS07385	COG0518	GMP synthase (glutamine-hydrolyzing) activity
F0P98_RS07385	COG0519	Catalyzes the synthesis of GMP from XMP
F0P98_RS07415	COG0084	hydrolase, TatD family'
F0P98_RS07435	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
F0P98_RS07460	COG2003	Belongs to the UPF0758 family
F0P98_RS07470	COG0024	Methionine aminopeptidase
F0P98_RS07485	COG1475	DNA binding
F0P98_RS07500	COG5489	Protein of unknown function (DUF736)
F0P98_RS07520	COG0812	UDP-N-acetylmuramate dehydrogenase activity
F0P98_RS07525	COG0167	dihydroorotate dehydrogenase activity
F0P98_RS07540	COG1012	belongs to the aldehyde dehydrogenase family
F0P98_RS07565	COG0083	homoserine kinase activity
F0P98_RS07570	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
F0P98_RS07580	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
F0P98_RS07585	COG0124	histidyl-tRNA synthetase
F0P98_RS07595	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
F0P98_RS07600	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
F0P98_RS07605	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
F0P98_RS07610	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
F0P98_RS07610	COG0131	Imidazoleglycerol-phosphate dehydratase
F0P98_RS07615	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
F0P98_RS07620	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
F0P98_RS07630	COG0140	phosphoribosyl-ATP diphosphatase activity
F0P98_RS07630	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
F0P98_RS07655	COG3485	protocatechuate 3,4-dioxygenase
F0P98_RS07665	COG0531	amino acid
F0P98_RS07680	COG1285	pathogenesis
F0P98_RS07685	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
F0P98_RS07690	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
F0P98_RS07695	COG0235	Class ii aldolase
F0P98_RS07700	COG0531	amino acid
F0P98_RS07705	COG0531	amino acid
F0P98_RS07715	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
F0P98_RS07720	COG0277	FAD linked oxidase domain protein
F0P98_RS07740	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
F0P98_RS07770	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
F0P98_RS07770	COG1918	ferrous iron import across plasma membrane
F0P98_RS07780	COG2249	NAD(P)H dehydrogenase (quinone) activity
F0P98_RS07785	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
F0P98_RS07790	COG0505	Belongs to the CarA family
F0P98_RS07795	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
F0P98_RS07800	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
F0P98_RS07810	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
F0P98_RS07820	COG3279	Response regulator of the LytR AlgR family
F0P98_RS07840	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
F0P98_RS07850	COG2205	protein histidine kinase activity
F0P98_RS07850	COG2198	Histidine kinase
F0P98_RS07850	COG0784	Response regulator, receiver
F0P98_RS07855	COG1024	Enoyl-CoA hydratase
F0P98_RS07860	COG0318	PFAM AMP-dependent synthetase and ligase
F0P98_RS07870	COG2885	chlorophyll binding
F0P98_RS07870	COG3047	cAMP biosynthetic process
F0P98_RS07875	COG3706	GGDEF domain
F0P98_RS07885	COG1017	nitric oxide dioxygenase activity
F0P98_RS07885	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
F0P98_RS07940	COG1228	amidohydrolase
F0P98_RS07985	COG0840	transmembrane signaling receptor activity
F0P98_RS07985	COG0840	transmembrane signaling receptor activity
F0P98_RS07990	COG0840	transmembrane signaling receptor activity
F0P98_RS08000	COG0835	chemotaxis
F0P98_RS08005	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
F0P98_RS08015	COG0840	transmembrane signaling receptor activity
F0P98_RS08020	COG0840	transmembrane signaling receptor activity
F0P98_RS08020	COG0840	transmembrane signaling receptor activity
F0P98_RS08025	COG0840	transmembrane signaling receptor activity
F0P98_RS08040	COG0745	RESPONSE REGULATOR receiver
F0P98_RS08050	COG0835	chemotaxis
F0P98_RS08065	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
F0P98_RS08070	COG2198	Histidine kinase
F0P98_RS08070	COG0784	Response regulator, receiver
F0P98_RS08070	COG0643	Histidine kinase
F0P98_RS08125	COG1338	Plays a role in the flagellum-specific transport system
F0P98_RS08130	COG3190	flagellar
F0P98_RS08170	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
F0P98_RS08175	COG1766	The M ring may be actively involved in energy transduction
F0P98_RS08180	COG1677	Flagellar hook-basal body complex protein FliE
F0P98_RS08185	COG0438	transferase activity, transferring glycosyl groups
F0P98_RS08185	COG1216	Glycosyl transferase, family 2
F0P98_RS08210	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
F0P98_RS08230	COG2201	protein-glutamate methylesterase activity
F0P98_RS08295	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
F0P98_RS08305	COG4787	bacterial-type flagellum-dependent cell motility
F0P98_RS08310	COG1749	Flagellar hook protein flgE
F0P98_RS08315	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
F0P98_RS08330	COG0835	chemotaxis
F0P98_RS08330	COG0784	Response regulator, receiver
F0P98_RS08350	COG5002	protein histidine kinase activity
F0P98_RS08380	COG2915	High frequency lysogenization protein hflD homolog
F0P98_RS08385	COG0482	sulfurtransferase activity
F0P98_RS08405	COG0542	response to heat
F0P98_RS08435	COG1408	metallophosphoesterase
F0P98_RS08440	COG0492	ferredoxin-NADP+ reductase activity
F0P98_RS08445	COG1674	ftsk spoiiie
F0P98_RS08450	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
F0P98_RS08455	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
F0P98_RS08460	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
F0P98_RS08465	COG0837	glucose binding
F0P98_RS08470	COG1446	asparaginase
F0P98_RS08475	COG3142	Participates in the control of copper homeostasis
F0P98_RS08520	COG0789	Transcriptional regulator
F0P98_RS08550	COG3118	belongs to the thioredoxin family
F0P98_RS08580	COG0446	pyridine nucleotide-disulphide oxidoreductase
F0P98_RS08585	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
F0P98_RS08590	COG0640	Transcriptional regulator
F0P98_RS08595	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
F0P98_RS08605	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
F0P98_RS08610	COG1271	oxidase subunit
F0P98_RS08615	COG1294	oxidase, subunit
F0P98_RS08625	COG4988	ABC transporter
F0P98_RS08630	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
F0P98_RS08770	COG4944	Protein of unknown function (DUF1109)
F0P98_RS08775	COG1595	DNA-templated transcription, initiation
F0P98_RS08780	COG1473	amidohydrolase
F0P98_RS08785	COG1064	alcohol dehydrogenase
F0P98_RS08825	COG2823	Periplasmic or secreted lipoprotein
F0P98_RS08845	COG1335	isochorismatase
F0P98_RS08850	COG1028	Short-chain dehydrogenase reductase Sdr
F0P98_RS08900	COG2183	response to ionizing radiation
F0P98_RS08920	COG3243	poly(R)-hydroxyalkanoic acid synthase
F0P98_RS08930	COG1183	phosphatidylcholine synthase activity
F0P98_RS08950	COG2974	May be involved in recombination
F0P98_RS09150	COG1196	nuclear chromosome segregation
F0P98_RS09160	COG5449	Phage conserved hypothetical protein BR0599
F0P98_RS09205	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
F0P98_RS09240	COG0084	hydrolase, TatD family'
F0P98_RS09245	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
F0P98_RS09275	COG1393	Belongs to the ArsC family
F0P98_RS09300	COG2860	membrane
F0P98_RS09325	COG0386	Belongs to the glutathione peroxidase family
F0P98_RS09330	COG0339	signal peptide processing
F0P98_RS09335	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
F0P98_RS09360	COG3104	oligopeptide transport
F0P98_RS09370	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
F0P98_RS09395	COG0583	DNA-binding transcription factor activity
F0P98_RS09405	COG0513	Belongs to the DEAD box helicase family
F0P98_RS09410	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
F0P98_RS09415	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
F0P98_RS09420	COG1278	Cold shock
F0P98_RS09435	COG2081	HI0933 family
F0P98_RS09440	COG2200	EAL domain
F0P98_RS09445	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
F0P98_RS09450	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
F0P98_RS09460	COG1862	Preprotein translocase
F0P98_RS09465	COG0343	queuine tRNA-ribosyltransferase activity
F0P98_RS09470	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
F0P98_RS09475	COG1522	sequence-specific DNA binding
F0P98_RS09480	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
F0P98_RS09510	COG0583	DNA-binding transcription factor activity
F0P98_RS09535	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
F0P98_RS09550	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
F0P98_RS09555	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
F0P98_RS09565	COG3135	benzoate transporter
F0P98_RS09575	COG0405	Gamma-glutamyltransferase
F0P98_RS09580	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
F0P98_RS09590	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
F0P98_RS09595	COG0742	ribosomal rna small subunit methyltransferase
F0P98_RS09600	COG0326	Molecular chaperone. Has ATPase activity
F0P98_RS09610	COG0552	protein localization to endoplasmic reticulum
F0P98_RS09615	COG1194	a g-specific adenine glycosylase
F0P98_RS09620	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
F0P98_RS09635	COG4591	ABC-type transport system involved in lipoprotein release permease component
F0P98_RS09660	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
F0P98_RS09685	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
F0P98_RS09690	COG0837	glucose binding
F0P98_RS09700	COG0129	dihydroxy-acid dehydratase activity
F0P98_RS09705	COG0800	Aldolase
F0P98_RS09720	COG0395	ABC-type sugar transport system, permease component
F0P98_RS09755	COG2350	Protein conserved in bacteria
F0P98_RS09760	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
F0P98_RS09765	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
F0P98_RS09770	COG1187	pseudouridine synthase activity
F0P98_RS09790	COG0436	Aminotransferase
F0P98_RS09820	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
F0P98_RS09830	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
F0P98_RS09835	COG3088	subunit of a heme lyase
F0P98_RS09840	COG4235	cytochrome complex assembly
F0P98_RS09850	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
F0P98_RS09855	COG1793	dna ligase
F0P98_RS09860	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
F0P98_RS09865	COG4988	ABC transporter
F0P98_RS09875	COG1294	oxidase, subunit
F0P98_RS09915	COG0165	Argininosuccinate lyase
F0P98_RS09930	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
F0P98_RS09935	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
F0P98_RS09940	COG0137	argininosuccinate synthase activity
F0P98_RS09945	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
F0P98_RS09960	COG2166	iron-sulfur cluster assembly
F0P98_RS09980	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
F0P98_RS10015	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
F0P98_RS10020	COG0402	S-adenosylhomocysteine deaminase activity
F0P98_RS10025	COG3548	integral membrane protein
F0P98_RS10030	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
F0P98_RS10035	COG1509	lysine 2,3-aminomutase activity
F0P98_RS10040	COG3300	MHYT domain
F0P98_RS10040	COG5001	Diguanylate cyclase
F0P98_RS10060	COG0501	Belongs to the peptidase M48B family
F0P98_RS10065	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
F0P98_RS10070	COG1028	Short-chain dehydrogenase reductase Sdr
F0P98_RS10090	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
F0P98_RS10095	COG0860	N-Acetylmuramoyl-L-alanine amidase
F0P98_RS10100	COG0802	atpase or kinase
F0P98_RS10105	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
F0P98_RS10105	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
F0P98_RS10110	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
F0P98_RS10115	COG1570	exodeoxyribonuclease VII activity
F0P98_RS10125	COG1262	PFAM Formylglycine-generating sulfatase enzyme
F0P98_RS10150	COG3040	lipid binding
F0P98_RS10155	COG1473	amidohydrolase
F0P98_RS10160	COG1228	amidohydrolase
F0P98_RS10165	COG3712	iron ion homeostasis
F0P98_RS10185	COG1960	acyl-CoA dehydrogenase activity
F0P98_RS10195	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
F0P98_RS10230	COG0322	excinuclease ABC activity
F0P98_RS10240	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
F0P98_RS10245	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
F0P98_RS10250	COG1663	tetraacyldisaccharide 4'-kinase activity
F0P98_RS10260	COG0848	biopolymer transport protein
F0P98_RS10280	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
F0P98_RS10290	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
F0P98_RS10295	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
F0P98_RS10300	COG0195	Participates in both transcription termination and antitermination
F0P98_RS10305	COG0779	Required for maturation of 30S ribosomal subunits
F0P98_RS10315	COG1007	ATP synthesis coupled electron transport
F0P98_RS10360	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
F0P98_RS10365	COG0649	NAD binding
F0P98_RS10370	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
F0P98_RS10375	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
F0P98_RS10380	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
F0P98_RS10395	COG0149	triose-phosphate isomerase activity
F0P98_RS10410	COG0726	polysaccharide deacetylase
F0P98_RS10415	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
F0P98_RS10420	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
F0P98_RS10425	COG2755	lipolytic protein G-D-S-L family
F0P98_RS10425	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
F0P98_RS10430	COG0159	tryptophan synthase activity
F0P98_RS10440	COG0133	tryptophan synthase activity
F0P98_RS10450	COG0135	phosphoribosylanthranilate isomerase activity
F0P98_RS10455	COG0101	tRNA pseudouridine synthase activity
F0P98_RS10470	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
F0P98_RS10475	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
F0P98_RS10480	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
F0P98_RS10485	COG2890	protein-(glutamine-N5) methyltransferase activity
F0P98_RS10495	COG0688	phosphatidylethanolamine metabolic process
F0P98_RS10515	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
F0P98_RS10525	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
F0P98_RS10530	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
F0P98_RS10540	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
F0P98_RS10545	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
F0P98_RS10550	COG1534	Rna-binding protein
F0P98_RS10570	COG1238	metal cluster binding
F0P98_RS10580	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
F0P98_RS10585	COG2840	Smr protein MutS2
F0P98_RS10590	COG0585	pseudouridine synthase activity
F0P98_RS10595	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
F0P98_RS10600	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
F0P98_RS10605	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
F0P98_RS10610	COG0148	phosphopyruvate hydratase activity
F0P98_RS10620	COG2877	3-deoxy-8-phosphooctulonate synthase activity
F0P98_RS10625	COG0504	CTP synthase activity
F0P98_RS10645	COG0306	phosphate transporter
F0P98_RS10655	COG1253	flavin adenine dinucleotide binding
F0P98_RS10665	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
F0P98_RS10685	COG0493	'glutamate synthase
F0P98_RS10690	COG0069	glutamate synthase activity
F0P98_RS10695	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
F0P98_RS10720	COG0348	domain, Protein
F0P98_RS10750	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
F0P98_RS10765	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
F0P98_RS10770	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
F0P98_RS10795	COG0464	growth
F0P98_RS10820	COG0542	response to heat
F0P98_RS10825	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
F0P98_RS10830	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
F0P98_RS10830	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
F0P98_RS10960	COG0587	DNA-directed DNA polymerase activity
F0P98_RS11000	COG0556	nucleotide-excision repair
F0P98_RS11045	COG3275	phosphorelay sensor kinase activity
F0P98_RS11050	COG1611	Belongs to the LOG family
F0P98_RS11060	COG2095	MarC family integral membrane protein
F0P98_RS11065	COG0300	oxidoreductase activity
F0P98_RS11070	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
F0P98_RS11110	COG2969	positive regulation of protein catabolic process
F0P98_RS11115	COG0625	glutathione transferase activity
F0P98_RS11120	COG2857	Cytochrome c1
F0P98_RS11125	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
F0P98_RS11130	COG0723	plastoquinol--plastocyanin reductase activity
F0P98_RS11135	COG0741	lytic transglycosylase activity
F0P98_RS11140	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
F0P98_RS11145	COG1129	ABC transporter
F0P98_RS11145	COG0842	Transport permease protein
F0P98_RS11150	COG1131	(ABC) transporter
F0P98_RS11160	COG1309	transcriptional regulator
F0P98_RS11165	COG1702	phosphate starvation-inducible protein PhoH
F0P98_RS11170	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
F0P98_RS11185	COG4535	Mg2 and Co2 transporter CorC
F0P98_RS11205	COG1012	belongs to the aldehyde dehydrogenase family
F0P98_RS11210	COG1177	transmembrane transport
F0P98_RS11215	COG1176	ABC-type spermidine putrescine transport system, permease component I
F0P98_RS11220	COG3842	ATPase activity
F0P98_RS11225	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
F0P98_RS11235	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
F0P98_RS11265	COG0745	RESPONSE REGULATOR receiver
F0P98_RS11275	COG2703	oxygen carrier activity
F0P98_RS11280	COG0477	Major facilitator Superfamily
F0P98_RS11290	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
F0P98_RS11300	COG3759	membrane
F0P98_RS11315	COG2733	membrane
F0P98_RS11325	COG0251	oxidation-reduction process
F0P98_RS11335	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
F0P98_RS11335	COG0392	lysyltransferase activity
F0P98_RS11370	COG2824	Alkylphosphonate utilization operon protein PhnA
F0P98_RS11405	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
F0P98_RS11415	COG1451	nucleotide metabolic process
F0P98_RS11435	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
F0P98_RS11440	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
F0P98_RS11455	COG2814	Major facilitator Superfamily
F0P98_RS11480	COG0204	Acyl-transferase
F0P98_RS11485	COG5001	Diguanylate cyclase
F0P98_RS11485	COG5002	protein histidine kinase activity
F0P98_RS11485	COG3447	MASE1 domain protein
F0P98_RS11490	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
F0P98_RS11515	COG1228	amidohydrolase
F0P98_RS11520	COG1619	proteins homologs of microcin C7 resistance protein MccF
F0P98_RS11525	COG5001	Diguanylate cyclase
F0P98_RS11525	COG3300	MHYT domain
F0P98_RS11530	COG1703	isobutyryl-CoA mutase activity
F0P98_RS11530	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
F0P98_RS11530	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
F0P98_RS11545	COG0183	Belongs to the thiolase family
F0P98_RS11560	COG4804	nuclease activity
F0P98_RS11565	COG2003	Belongs to the UPF0758 family
F0P98_RS11585	COG1475	DNA binding
F0P98_RS11590	COG5489	Protein of unknown function (DUF736)
F0P98_RS11660	COG1396	sequence-specific DNA binding
F0P98_RS11670	COG0583	DNA-binding transcription factor activity
F0P98_RS11700	COG0745	RESPONSE REGULATOR receiver
F0P98_RS11705	COG2205	protein histidine kinase activity
F0P98_RS11720	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
F0P98_RS11725	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
F0P98_RS11735	COG0583	DNA-binding transcription factor activity
F0P98_RS11755	COG4962	Type ii secretion system protein e
F0P98_RS11760	COG3838	Conjugal transfer protein Trbc
F0P98_RS11770	COG3451	type IV secretory pathway VirB4
F0P98_RS11785	COG3846	protein secretion by the type IV secretion system
F0P98_RS11800	COG2948	multi-organism process
F0P98_RS11820	COG1960	acyl-CoA dehydrogenase activity
F0P98_RS11825	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
F0P98_RS11830	COG1278	Cold shock
F0P98_RS11835	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
F0P98_RS11845	COG1472	Belongs to the glycosyl hydrolase 3 family
F0P98_RS11850	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
F0P98_RS11855	COG2954	triphosphatase activity
F0P98_RS11860	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
F0P98_RS11875	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
F0P98_RS11890	COG0681	Belongs to the peptidase S26 family
F0P98_RS11895	COG0481	GTPase activity
F0P98_RS11900	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
F0P98_RS11915	COG1024	Enoyl-CoA hydratase
F0P98_RS11915	COG1250	3-hydroxyacyl-CoA dehydrogenase
F0P98_RS11920	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
F0P98_RS11925	COG3278	Belongs to the heme-copper respiratory oxidase family
F0P98_RS11940	COG2010	Cytochrome c
F0P98_RS11960	COG2217	Heavy metal translocating P-type atpase
F0P98_RS11990	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
F0P98_RS11995	COG3706	GGDEF domain
F0P98_RS12010	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
F0P98_RS12015	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
F0P98_RS12020	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
F0P98_RS12060	COG1827	regulation of RNA biosynthetic process
F0P98_RS12070	COG0753	catalase activity
F0P98_RS12090	COG0534	Mate efflux family protein
F0P98_RS12095	COG0673	inositol 2-dehydrogenase activity
F0P98_RS12105	COG1501	Belongs to the glycosyl hydrolase 31 family
F0P98_RS12110	COG2222	sugar isomerase
F0P98_RS12115	COG1940	carbohydrate kinase activity
F0P98_RS12125	COG1349	DNA-binding transcription factor activity
F0P98_RS12130	COG0335	large ribosomal subunit rRNA binding
F0P98_RS12135	COG0336	Belongs to the RNA methyltransferase TrmD family
F0P98_RS12140	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
F0P98_RS12155	COG2070	2-Nitropropane dioxygenase
F0P98_RS12160	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
F0P98_RS12185	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
F0P98_RS12190	COG1845	cytochrome c oxidase, subunit III
F0P98_RS12195	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
F0P98_RS12220	COG4206	TonB-dependent receptor
F0P98_RS12235	COG4974	Belongs to the 'phage' integrase family
F0P98_RS12300	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
F0P98_RS12310	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
F0P98_RS12315	COG0196	riboflavin kinase activity
F0P98_RS12320	COG0728	peptidoglycan biosynthetic process
F0P98_RS12330	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
F0P98_RS12340	COG0211	Belongs to the bacterial ribosomal protein bL27 family
F0P98_RS12350	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
F0P98_RS12385	COG4452	Inner membrane protein CreD
F0P98_RS12390	COG5002	protein histidine kinase activity
F0P98_RS12390	COG5001	Diguanylate cyclase
F0P98_RS12395	COG2205	protein histidine kinase activity
F0P98_RS12400	COG0745	RESPONSE REGULATOR receiver
F0P98_RS12405	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
F0P98_RS12415	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
F0P98_RS12435	COG3590	peptidase
F0P98_RS12465	COG0588	phosphoglycerate mutase activity
F0P98_RS12470	COG1515	deoxyribonuclease V activity
F0P98_RS12475	COG1741	Belongs to the pirin family
F0P98_RS12480	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
F0P98_RS12495	COG1966	Carbon starvation protein
F0P98_RS12500	COG2879	small protein
F0P98_RS12515	COG0823	Involved in the tonB-independent uptake of proteins
F0P98_RS12515	COG1506	peptidase
F0P98_RS12520	COG1297	OPT oligopeptide transporter protein
F0P98_RS12525	COG3104	oligopeptide transport
F0P98_RS12535	COG4771	TonB-dependent receptor
F0P98_RS12545	COG4948	Mandelate Racemase Muconate Lactonizing
F0P98_RS12555	COG2197	response regulator
F0P98_RS12565	COG0798	PFAM Bile acid sodium symporter
F0P98_RS12580	COG0431	NADPH-dependent FMN reductase
F0P98_RS12605	COG0629	single-stranded DNA binding
F0P98_RS12635	COG2190	(PTS) system
F0P98_RS12635	COG2211	Major facilitator Superfamily
F0P98_RS12640	COG1082	Xylose isomerase domain protein TIM barrel
F0P98_RS12650	COG0366	Alpha amylase catalytic
F0P98_RS12655	COG0142	geranyltranstransferase activity
F0P98_RS12665	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
F0P98_RS12675	COG0527	aspartate kinase activity
F0P98_RS12680	COG0384	phenazine biosynthesis protein PhzF
F0P98_RS12685	COG0384	phenazine biosynthesis protein PhzF
F0P98_RS12695	COG1214	PFAM Peptidase M22, glycoprotease
F0P98_RS12700	COG1199	ATP-dependent helicase activity
F0P98_RS12710	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
F0P98_RS12725	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
F0P98_RS12740	COG1643	Atp-dependent helicase
F0P98_RS12745	COG0783	Belongs to the Dps family
F0P98_RS12755	COG0515	serine threonine protein kinase
F0P98_RS12755	COG2815	serine threonine protein kinase
F0P98_RS12770	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
F0P98_RS12775	COG0602	queuosine metabolic process
F0P98_RS12785	COG2885	chlorophyll binding
F0P98_RS12810	COG0824	Thioesterase
F0P98_RS12815	COG2255	four-way junction helicase activity
F0P98_RS12825	COG0632	four-way junction helicase activity
F0P98_RS12830	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
F0P98_RS12835	COG0217	transcriptional regulatory protein
F0P98_RS12865	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
F0P98_RS12900	COG0488	(ABC) transporter
F0P98_RS12905	COG4771	TonB-dependent receptor
F0P98_RS12910	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
F0P98_RS12910	COG4651	solute:proton antiporter activity
F0P98_RS12915	COG0583	DNA-binding transcription factor activity
F0P98_RS12930	COG0542	response to heat
F0P98_RS12935	COG1595	DNA-templated transcription, initiation
F0P98_RS12945	COG4771	TonB-dependent receptor
F0P98_RS12995	COG1877	trehalose-phosphatase activity
F0P98_RS13000	COG3387	PFAM Glycoside hydrolase 15-related
F0P98_RS13005	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
F0P98_RS13010	COG3011	Protein conserved in bacteria
F0P98_RS13025	COG0564	pseudouridine synthase activity
F0P98_RS13030	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
F0P98_RS13040	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
F0P98_RS13055	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
F0P98_RS13070	COG1137	ATPase activity
F0P98_RS13085	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
F0P98_RS13090	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
F0P98_RS13095	COG1660	Displays ATPase and GTPase activities
F0P98_RS13110	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
F0P98_RS13115	COG2239	Acts as a magnesium transporter
F0P98_RS13130	COG0540	Belongs to the ATCase OTCase family
F0P98_RS13145	COG2818	Glycosylase
F0P98_RS13205	COG3540	Alkaline phosphatase
F0P98_RS13235	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
F0P98_RS13240	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
F0P98_RS13245	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
F0P98_RS13255	COG1028	Short-chain dehydrogenase reductase Sdr
F0P98_RS13270	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
F0P98_RS13275	COG0333	Belongs to the bacterial ribosomal protein bL32 family
F0P98_RS13280	COG1399	metal-binding, possibly nucleic acid-binding protein
F0P98_RS13305	COG0714	Associated with various cellular activities
F0P98_RS13315	COG1305	Transglutaminase-like
F0P98_RS13330	COG0537	adenosine 5'-monophosphoramidase activity
F0P98_RS13345	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
F0P98_RS13360	COG1234	tRNA 3'-trailer cleavage
F0P98_RS13365	COG3642	lipopolysaccharide core region biosynthetic process
F0P98_RS13370	COG0859	PFAM glycosyl transferase family 9
F0P98_RS13385	COG0631	protein serine/threonine phosphatase activity
F0P98_RS13390	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
F0P98_RS13405	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
F0P98_RS13410	COG1388	LysM domain
F0P98_RS13410	COG3942	CHAP domain
F0P98_RS13415	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
F0P98_RS13450	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
F0P98_RS13460	COG0544	peptidyl-prolyl cis-trans isomerase activity
F0P98_RS13500	COG0473	3-isopropylmalate dehydrogenase activity
F0P98_RS13515	COG4783	chaperone-mediated protein folding
F0P98_RS13525	COG5002	protein histidine kinase activity
F0P98_RS13530	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
F0P98_RS13535	COG0248	Ppx GppA phosphatase
F0P98_RS13540	COG0438	transferase activity, transferring glycosyl groups
F0P98_RS13550	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
F0P98_RS13565	COG2833	Protein of unknown function (DUF455)
F0P98_RS13585	COG0285	dihydrofolate synthase activity
F0P98_RS13595	COG0588	phosphoglycerate mutase activity
F0P98_RS13610	COG1063	alcohol dehydrogenase
F0P98_RS13625	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
F0P98_RS13630	COG4208	sulfate ABC transporter
F0P98_RS13635	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
F0P98_RS13640	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
F0P98_RS13660	COG1187	pseudouridine synthase activity
F0P98_RS13680	COG1902	pentaerythritol trinitrate reductase activity
F0P98_RS13680	COG0446	pyridine nucleotide-disulphide oxidoreductase
F0P98_RS13690	COG0625	glutathione transferase activity
F0P98_RS13695	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
F0P98_RS13710	COG0745	RESPONSE REGULATOR receiver
F0P98_RS13715	COG2205	protein histidine kinase activity
F0P98_RS13730	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
F0P98_RS13745	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
F0P98_RS13760	COG0154	amidase activity
F0P98_RS13770	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
F0P98_RS13775	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
F0P98_RS13780	COG0203	ribosomal protein L17
F0P98_RS13785	COG0202	RNA polymerase activity
F0P98_RS13790	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
F0P98_RS13800	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
F0P98_RS13805	COG0201	protein transport
F0P98_RS13810	COG0200	Binds to the 23S rRNA
F0P98_RS13815	COG1841	ribosomal large subunit assembly
F0P98_RS13820	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
F0P98_RS13825	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
F0P98_RS13835	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
F0P98_RS13840	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
F0P98_RS13845	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
F0P98_RS13850	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
F0P98_RS13860	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
F0P98_RS13865	COG0255	Belongs to the universal ribosomal protein uL29 family
F0P98_RS13870	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
F0P98_RS13875	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
F0P98_RS13880	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
F0P98_RS13885	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
F0P98_RS13890	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
F0P98_RS13895	COG0089	rRNA binding
F0P98_RS13900	COG0088	Forms part of the polypeptide exit tunnel
F0P98_RS13905	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
F0P98_RS13910	COG0051	transcription antitermination factor activity, RNA binding
F0P98_RS13920	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
F0P98_RS13925	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
F0P98_RS13935	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
F0P98_RS13940	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
F0P98_RS13945	COG0085	RNA polymerase activity
F0P98_RS13950	COG0222	ribosome binding
F0P98_RS13955	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
F0P98_RS13960	COG0081	regulation of translation
F0P98_RS13965	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
F0P98_RS13970	COG0250	Participates in transcription elongation, termination and antitermination
F0P98_RS13985	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
F0P98_RS14005	COG1446	asparaginase
F0P98_RS14015	COG4206	TonB-dependent receptor
F0P98_RS14020	COG0012	GTP binding
F0P98_RS14025	COG0193	aminoacyl-tRNA hydrolase activity
F0P98_RS14035	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
F0P98_RS14045	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
F0P98_RS14060	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
F0P98_RS14065	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
F0P98_RS14095	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
F0P98_RS14100	COG1295	ribonuclease BN
F0P98_RS14120	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
F0P98_RS14125	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
F0P98_RS14185	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
F0P98_RS14185	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
F0P98_RS14215	COG3706	GGDEF domain
F0P98_RS14235	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
F0P98_RS14240	COG1538	Outer membrane efflux protein
F0P98_RS14245	COG1519	Transferase
F0P98_RS14250	COG1560	Kdo2-lipid A biosynthetic process
F0P98_RS14260	COG0297	glycogen (starch) synthase activity
F0P98_RS14270	COG3916	Acyl-homoserine-lactone synthase
F0P98_RS14280	COG2197	response regulator
F0P98_RS14295	COG2610	gluconate transmembrane transporter activity
F0P98_RS14300	COG1737	Transcriptional regulator
F0P98_RS14305	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
F0P98_RS14315	COG0786	glutamate:sodium symporter activity
F0P98_RS14320	COG0405	Gamma-glutamyltransferase
F0P98_RS14325	COG0641	radical SAM
F0P98_RS14330	COG3119	arylsulfatase activity
F0P98_RS14335	COG0280	phosphate acetyltransferase
F0P98_RS14335	COG0281	malic enzyme
F0P98_RS14345	COG0405	Gamma-glutamyltransferase
F0P98_RS14350	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
F0P98_RS14355	COG0583	DNA-binding transcription factor activity
F0P98_RS14365	COG4206	TonB-dependent receptor
F0P98_RS14370	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
F0P98_RS14380	COG1162	GTPase activity
F0P98_RS14385	COG0436	Aminotransferase
F0P98_RS14405	COG0513	Belongs to the DEAD box helicase family
F0P98_RS14415	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
F0P98_RS14425	COG3964	amidohydrolase
F0P98_RS14430	COG1228	amidohydrolase
F0P98_RS14435	COG1307	EDD domain protein, DegV family
F0P98_RS14450	COG2203	Gaf domain
F0P98_RS14450	COG3706	GGDEF domain
F0P98_RS14450	COG4251	negative regulation of phosphorylation
F0P98_RS14450	COG5001	Diguanylate cyclase
F0P98_RS14455	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
F0P98_RS14460	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
F0P98_RS14505	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
F0P98_RS14510	COG0218	Necessary for normal cell division and for the maintenance of normal septation
F0P98_RS14525	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
F0P98_RS14550	COG0617	tRNA 3'-terminal CCA addition
F0P98_RS14565	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
F0P98_RS14570	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
F0P98_RS14575	COG1609	Transcriptional regulator
F0P98_RS14580	COG0738	Major facilitator superfamily
F0P98_RS14585	COG0837	glucose binding
F0P98_RS14595	COG3525	Glycosyl hydrolase, family 20, catalytic domain
F0P98_RS14600	COG0837	glucose binding
F0P98_RS14610	COG3525	Glycosyl hydrolase, family 20, catalytic domain
F0P98_RS14615	COG3876	Protein conserved in bacteria
F0P98_RS14620	COG3525	Glycosyl hydrolase, family 20, catalytic domain
F0P98_RS14625	COG0662	Cupin 2, conserved barrel domain protein
F0P98_RS14645	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
F0P98_RS14650	COG4191	Histidine kinase
F0P98_RS14655	COG0784	Response regulator, receiver
F0P98_RS14660	COG4251	negative regulation of phosphorylation
F0P98_RS14670	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
F0P98_RS14690	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
F0P98_RS14695	COG0321	lipoyl(octanoyl) transferase activity
F0P98_RS14700	COG2921	Belongs to the UPF0250 family
F0P98_RS14715	COG1686	Belongs to the peptidase S11 family
F0P98_RS14725	COG2951	lytic endotransglycosylase activity
F0P98_RS14730	COG0772	Belongs to the SEDS family
F0P98_RS14735	COG0768	penicillin binding
F0P98_RS14745	COG1792	Involved in formation and maintenance of cell shape
F0P98_RS14750	COG1077	Cell shape determining protein MreB Mrl
F0P98_RS14755	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
F0P98_RS14775	COG0308	aminopeptidase N
F0P98_RS14780	COG2226	methyltransferase
F0P98_RS14795	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
F0P98_RS14800	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
F0P98_RS14805	COG1309	transcriptional regulator
F0P98_RS14810	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
F0P98_RS14815	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
F0P98_RS14840	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
F0P98_RS14850	COG2832	Protein of unknown function (DUF454)
F0P98_RS14865	COG1505	serine-type exopeptidase activity
F0P98_RS14885	COG3154	lipid carrier protein
F0P98_RS14895	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
F0P98_RS14900	COG0826	peptidase U32
F0P98_RS14905	COG0826	peptidase U32
F0P98_RS14930	COG0181	hydroxymethylbilane synthase activity
F0P98_RS14950	COG2409	Drug exporters of the RND superfamily
F0P98_RS14970	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
F0P98_RS15025	COG1028	Short-chain dehydrogenase reductase Sdr
F0P98_RS15030	COG0318	PFAM AMP-dependent synthetase and ligase
F0P98_RS15045	COG2076	Multidrug Resistance protein
F0P98_RS15050	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
F0P98_RS15060	COG1216	Glycosyl transferase, family 2
F0P98_RS15060	COG0438	transferase activity, transferring glycosyl groups
F0P98_RS15080	COG1459	type II secretion system
F0P98_RS15135	COG1450	Type ii and iii secretion system protein
F0P98_RS15145	COG0626	cystathionine gamma-synthase activity
F0P98_RS15175	COG0625	glutathione transferase activity
F0P98_RS15185	COG0513	Belongs to the DEAD box helicase family
F0P98_RS15190	COG0720	synthase
F0P98_RS15205	COG1956	GAF domain-containing protein
F0P98_RS15215	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
F0P98_RS15220	COG0406	alpha-ribazole phosphatase activity
F0P98_RS15225	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
F0P98_RS15230	COG4206	TonB-dependent receptor
F0P98_RS15235	COG0546	phosphoglycolate phosphatase activity
F0P98_RS15240	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
F0P98_RS15285	COG0339	signal peptide processing
F0P98_RS15300	COG2132	Multicopper oxidase
F0P98_RS15350	COG0457	Tetratricopeptide repeat
F0P98_RS15350	COG3710	Transcriptional regulator
F0P98_RS15360	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
F0P98_RS15370	COG1136	(ABC) transporter
F0P98_RS15375	COG1136	(ABC) transporter
F0P98_RS15375	COG0577	efflux transmembrane transporter activity
F0P98_RS15380	COG1136	(ABC) transporter
F0P98_RS15380	COG0577	efflux transmembrane transporter activity
F0P98_RS15385	COG1136	(ABC) transporter
F0P98_RS15385	COG0577	efflux transmembrane transporter activity
F0P98_RS15390	COG0577	efflux transmembrane transporter activity
F0P98_RS15390	COG1136	(ABC) transporter
F0P98_RS15395	COG1136	(ABC) transporter
F0P98_RS15395	COG0577	efflux transmembrane transporter activity
F0P98_RS15415	COG0577	efflux transmembrane transporter activity
F0P98_RS15415	COG1136	(ABC) transporter
F0P98_RS15425	COG4191	Histidine kinase
F0P98_RS15430	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
F0P98_RS15440	COG0355	proton-transporting ATP synthase activity, rotational mechanism
F0P98_RS15445	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
F0P98_RS15450	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
F0P98_RS15455	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
F0P98_RS15460	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
F0P98_RS15465	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
F0P98_RS15475	COG0356	it plays a direct role in the translocation of protons across the membrane
F0P98_RS15490	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
F0P98_RS15520	COG2011	ABC-type metal ion transport system permease component
F0P98_RS15530	COG0697	spore germination
F0P98_RS15540	COG1666	GTP binding
F0P98_RS15550	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
F0P98_RS15555	COG1187	pseudouridine synthase activity
F0P98_RS15565	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
F0P98_RS15565	COG2205	protein histidine kinase activity
F0P98_RS15580	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
F0P98_RS15630	COG0025	NhaP-type Na H and K H
F0P98_RS15635	COG3384	dioxygenase
F0P98_RS15640	COG0583	DNA-binding transcription factor activity
F0P98_RS15645	COG5001	Diguanylate cyclase
F0P98_RS15660	COG3590	peptidase
F0P98_RS15685	COG2972	Histidine kinase
F0P98_RS15695	COG4941	Belongs to the sigma-70 factor family
F0P98_RS15700	COG5507	3-demethylubiquinone-9 3-methyltransferase
F0P98_RS15715	COG3795	YCII-related domain
F0P98_RS15720	COG3795	YCII-related domain
F0P98_RS15735	COG4804	nuclease activity
F0P98_RS15760	COG5489	Protein of unknown function (DUF736)
F0P98_RS15795	COG1192	Involved in chromosome partitioning
F0P98_RS15810	COG4959	Type IV secretory pathway protease TraF
F0P98_RS15820	COG1695	Transcriptional regulator
F0P98_RS15825	COG0701	Predicted permease
F0P98_RS15840	COG2226	methyltransferase
F0P98_RS15850	COG0583	DNA-binding transcription factor activity
F0P98_RS15870	COG4962	Type ii secretion system protein e
F0P98_RS15875	COG3838	Conjugal transfer protein Trbc
F0P98_RS15885	COG3451	type IV secretory pathway VirB4
F0P98_RS15915	COG2948	multi-organism process
F0P98_RS15950	COG5001	Diguanylate cyclase
F0P98_RS15950	COG5002	protein histidine kinase activity
F0P98_RS15965	COG3706	GGDEF domain
F0P98_RS15970	COG2200	EAL domain
F0P98_RS15995	COG3046	protein related to deoxyribodipyrimidine photolyase
F0P98_RS16000	COG0302	gtp cyclohydrolase
F0P98_RS16010	COG1595	DNA-templated transcription, initiation
F0P98_RS16020	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
F0P98_RS16030	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
F0P98_RS16055	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
F0P98_RS16070	COG3275	phosphorelay sensor kinase activity
F0P98_RS16085	COG0551	DNA topoisomerase type I activity
F0P98_RS16110	COG0582	viral genome integration into host DNA
F0P98_RS16125	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
F0P98_RS16130	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
F0P98_RS16130	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
F0P98_RS16145	COG2205	protein histidine kinase activity
F0P98_RS16150	COG0745	RESPONSE REGULATOR receiver
F0P98_RS16160	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
F0P98_RS16175	COG3209	COG3209 Rhs family protein
F0P98_RS16190	COG2076	Multidrug Resistance protein
F0P98_RS16235	COG1285	pathogenesis
F0P98_RS16240	COG1335	isochorismatase
F0P98_RS16250	COG1902	pentaerythritol trinitrate reductase activity
F0P98_RS16265	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
F0P98_RS16285	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
F0P98_RS16295	COG0697	spore germination
F0P98_RS16320	COG1960	acyl-CoA dehydrogenase activity
F0P98_RS16325	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
F0P98_RS16350	COG5001	Diguanylate cyclase
F0P98_RS16360	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
F0P98_RS16365	COG0583	DNA-binding transcription factor activity
F0P98_RS16375	COG0277	FAD linked oxidase domain protein
F0P98_RS16380	COG1304	FMN binding
F0P98_RS16385	COG2186	Transcriptional regulator
F0P98_RS16395	COG0681	Belongs to the peptidase S26 family
F0P98_RS16410	COG0339	signal peptide processing
F0P98_RS16415	COG0415	Belongs to the DNA photolyase family
F0P98_RS16465	COG0564	pseudouridine synthase activity
F0P98_RS16485	COG1181	Belongs to the D-alanine--D-alanine ligase family
F0P98_RS16500	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
F0P98_RS16505	COG0318	PFAM AMP-dependent synthetase and ligase
F0P98_RS16515	COG0596	Alpha beta hydrolase
F0P98_RS16520	COG1573	uracil-dna glycosylase
F0P98_RS16525	COG3012	SEC-C Motif Domain Protein
F0P98_RS16525	COG3318	Belongs to the UPF0149 family
F0P98_RS16530	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
F0P98_RS16540	COG0612	Peptidase, M16
F0P98_RS16550	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
F0P98_RS16560	COG1804	L-carnitine dehydratase bile acid-inducible protein F
F0P98_RS16565	COG1960	acyl-CoA dehydrogenase activity
F0P98_RS16570	COG1113	amino acid transport
F0P98_RS16580	COG1199	ATP-dependent helicase activity
F0P98_RS16590	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
F0P98_RS16610	COG3781	membrane
F0P98_RS16655	COG3209	COG3209 Rhs family protein
F0P98_RS16685	COG0625	glutathione transferase activity
F0P98_RS16700	COG1668	transmembrane transport
F0P98_RS16705	COG4555	ABC transporter
F0P98_RS16740	COG1131	(ABC) transporter
F0P98_RS16745	COG0842	Transport permease protein
F0P98_RS16750	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
F0P98_RS16765	COG0084	hydrolase, TatD family'
F0P98_RS16770	COG1643	Atp-dependent helicase
F0P98_RS16780	COG1187	pseudouridine synthase activity
F0P98_RS16790	COG0667	Aldo Keto reductase
F0P98_RS16810	COG2239	Acts as a magnesium transporter
F0P98_RS16815	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
F0P98_RS16815	COG0475	glutathione-regulated potassium exporter activity
F0P98_RS16840	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
F0P98_RS16850	COG0463	Glycosyl transferase, family 2
F0P98_RS16855	COG1028	Short-chain dehydrogenase reductase Sdr
F0P98_RS16860	COG2365	Tyrosine phosphatase family
F0P98_RS16865	COG4771	TonB-dependent receptor
F0P98_RS16895	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
F0P98_RS16910	COG0251	oxidation-reduction process
F0P98_RS16935	COG0408	coproporphyrinogen oxidase activity
F0P98_RS16940	COG2323	membrane
F0P98_RS16955	COG0589	response to stress
F0P98_RS16960	COG0210	DNA helicase
F0P98_RS16970	COG0267	Belongs to the bacterial ribosomal protein bL33 family
F0P98_RS16975	COG0227	Belongs to the bacterial ribosomal protein bL28 family
F0P98_RS17015	COG4771	TonB-dependent receptor
F0P98_RS17020	COG1429	ligase activity, forming nitrogen-metal bonds
F0P98_RS17040	COG0463	Glycosyl transferase, family 2
F0P98_RS17055	COG1475	DNA binding
F0P98_RS17060	COG1192	Involved in chromosome partitioning
F0P98_RS17065	COG0357	Ribosomal RNA small subunit methyltransferase G
F0P98_RS17070	COG2091	lysine biosynthetic process via aminoadipic acid
F0P98_RS17085	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
F0P98_RS17090	COG4149	molybdate abc transporter
F0P98_RS17095	COG0725	ABC transporter, periplasmic molybdate-binding protein
F0P98_RS17105	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
F0P98_RS17110	COG2181	nitrate reductase activity
F0P98_RS17115	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
F0P98_RS17120	COG1140	nitrate reductase beta subunit
F0P98_RS17125	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
F0P98_RS17130	COG2223	nitrite transmembrane transporter activity
F0P98_RS17140	COG0746	molybdenum cofactor guanylyltransferase activity
F0P98_RS17145	COG0314	molybdopterin synthase activity
F0P98_RS17155	COG0303	'Molybdopterin
F0P98_RS17160	COG0521	Mo-molybdopterin cofactor biosynthetic process
F0P98_RS17160	COG0315	cyclic pyranopterin monophosphate synthase activity
F0P98_RS17165	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
F0P98_RS17185	COG4771	TonB-dependent receptor
F0P98_RS17200	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
F0P98_RS17205	COG1120	ATPase activity
F0P98_RS17210	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
F0P98_RS17220	COG3162	membrane
F0P98_RS17240	COG0840	transmembrane signaling receptor activity
F0P98_RS17245	COG1971	Probably functions as a manganese efflux pump
F0P98_RS17260	COG2199	diguanylate cyclase activity
F0P98_RS17280	COG0745	RESPONSE REGULATOR receiver
F0P98_RS17285	COG0745	RESPONSE REGULATOR receiver
F0P98_RS17305	COG0729	surface antigen
F0P98_RS17325	COG0752	glycyl-tRNA synthetase alpha subunit
F0P98_RS17330	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
F0P98_RS17335	COG0518	GMP synthase (glutamine-hydrolyzing) activity
F0P98_RS17335	COG0519	Catalyzes the synthesis of GMP from XMP
F0P98_RS17345	COG0805	protein transport
F0P98_RS17365	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
F0P98_RS17370	COG2267	carboxylic ester hydrolase activity
F0P98_RS17380	COG2974	May be involved in recombination
F0P98_RS17385	COG0037	tRNA processing
F0P98_RS17410	COG2937	Belongs to the GPAT DAPAT family
F0P98_RS17420	COG0284	orotidine-5'-phosphate decarboxylase activity
F0P98_RS17425	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
F0P98_RS17430	COG3132	Protein of unknown function, DUF480
F0P98_RS17435	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
F0P98_RS17440	COG0210	DNA helicase
F0P98_RS17455	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
F0P98_RS17460	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
F0P98_RS17490	COG0840	transmembrane signaling receptor activity
F0P98_RS17505	COG1752	Esterase of the alpha-beta hydrolase superfamily
F0P98_RS17525	COG1429	ligase activity, forming nitrogen-metal bonds
F0P98_RS17530	COG4771	TonB-dependent receptor
F0P98_RS17540	COG3186	Phenylalanine-4-hydroxylase
F0P98_RS17550	COG2197	response regulator
F0P98_RS17600	COG1741	Belongs to the pirin family
F0P98_RS17605	COG0583	DNA-binding transcription factor activity
F0P98_RS17615	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
F0P98_RS17620	COG1074	ATP-dependent DNA helicase activity
F0P98_RS17625	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
F0P98_RS17630	COG1127	ABC transporter
F0P98_RS17635	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
F0P98_RS17640	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
F0P98_RS17655	COG2853	Lipoprotein
F0P98_RS17665	COG0386	Belongs to the glutathione peroxidase family
F0P98_RS17695	COG0531	amino acid
F0P98_RS17705	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
F0P98_RS17710	COG0861	Integral membrane protein TerC family
F0P98_RS17720	COG0584	glycerophosphoryl diester phosphodiesterase
F0P98_RS17740	COG0706	membrane insertase activity
F0P98_RS17745	COG0594	ribonuclease P activity
F0P98_RS17750	COG0230	Belongs to the bacterial ribosomal protein bL34 family