locus-tag	class	description
LQ335_RS00005	COG3135	benzoate transporter
LQ335_RS00020	COG2951	lytic endotransglycosylase activity
LQ335_RS00025	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
LQ335_RS00030	COG1262	PFAM Formylglycine-generating sulfatase enzyme
LQ335_RS00035	COG3706	GGDEF domain
LQ335_RS00065	COG0302	gtp cyclohydrolase
LQ335_RS00080	COG1566	PFAM secretion protein HlyD family protein
LQ335_RS00090	COG1289	transmembrane transporter activity
LQ335_RS00110	COG1074	ATP-dependent DNA helicase activity
LQ335_RS00115	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
LQ335_RS00120	COG1127	ABC transporter
LQ335_RS00125	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
LQ335_RS00130	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
LQ335_RS00145	COG2853	Lipoprotein
LQ335_RS00150	COG0386	Belongs to the glutathione peroxidase family
LQ335_RS00160	COG1322	Protein conserved in bacteria
LQ335_RS00175	COG0583	DNA-binding transcription factor activity
LQ335_RS00190	COG0531	amino acid
LQ335_RS00205	COG2378	regulation of single-species biofilm formation
LQ335_RS00210	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
LQ335_RS00215	COG0861	Integral membrane protein TerC family
LQ335_RS00225	COG0584	glycerophosphoryl diester phosphodiesterase
LQ335_RS00240	COG0706	membrane insertase activity
LQ335_RS00245	COG0594	ribonuclease P activity
LQ335_RS00250	COG0230	Belongs to the bacterial ribosomal protein bL34 family
LQ335_RS00255	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
LQ335_RS00265	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
LQ335_RS00270	COG0187	DNA topoisomerase II activity
LQ335_RS00275	COG1266	CAAX protease self-immunity
LQ335_RS00280	COG0501	Belongs to the peptidase M48B family
LQ335_RS00385	COG2814	Major facilitator Superfamily
LQ335_RS00440	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
LQ335_RS00450	COG4772	TonB-dependent receptor
LQ335_RS00485	COG0800	Aldolase
LQ335_RS00500	COG3186	Phenylalanine-4-hydroxylase
LQ335_RS00505	COG1522	sequence-specific DNA binding
LQ335_RS00510	COG1752	Esterase of the alpha-beta hydrolase superfamily
LQ335_RS00525	COG0671	phosphoesterase, PA-phosphatase related
LQ335_RS00540	COG1122	ATPase activity
LQ335_RS00555	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
LQ335_RS00560	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
LQ335_RS00575	COG0210	DNA helicase
LQ335_RS00595	COG3132	Protein of unknown function, DUF480
LQ335_RS00600	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
LQ335_RS00605	COG0284	orotidine-5'-phosphate decarboxylase activity
LQ335_RS00610	COG5640	endopeptidase activity
LQ335_RS00620	COG2937	Belongs to the GPAT DAPAT family
LQ335_RS00630	COG0037	tRNA processing
LQ335_RS00635	COG2974	May be involved in recombination
LQ335_RS00645	COG1803	Methylglyoxal synthase
LQ335_RS00650	COG0784	Response regulator, receiver
LQ335_RS00650	COG5002	protein histidine kinase activity
LQ335_RS00655	COG0493	'glutamate synthase
LQ335_RS00660	COG0067	glutamate synthase
LQ335_RS00660	COG0069	glutamate synthase activity
LQ335_RS00660	COG0070	glutamate synthase
LQ335_RS00680	COG1028	Short-chain dehydrogenase reductase Sdr
LQ335_RS00685	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
LQ335_RS00720	COG0640	Transcriptional regulator
LQ335_RS00740	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LQ335_RS00740	COG3453	Protein conserved in bacteria
LQ335_RS00755	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
LQ335_RS00780	COG0431	NADPH-dependent FMN reductase
LQ335_RS00795	COG0798	PFAM Bile acid sodium symporter
LQ335_RS00810	COG0659	secondary active sulfate transmembrane transporter activity
LQ335_RS00870	COG1111	helicase
LQ335_RS00870	COG1205	dead DEAH box helicase
LQ335_RS00905	COG0714	Associated with various cellular activities
LQ335_RS00925	COG0312	modulator of DNA gyrase
LQ335_RS00945	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LQ335_RS00965	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LQ335_RS00990	COG1881	PFAM PEBP family protein
LQ335_RS01000	COG1968	undecaprenyl-diphosphatase activity
LQ335_RS01005	COG0174	glutamine synthetase
LQ335_RS01010	COG0347	Belongs to the P(II) protein family
LQ335_RS01015	COG0004	ammonium transporteR
LQ335_RS01025	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
LQ335_RS01040	COG3852	Histidine kinase
LQ335_RS01045	COG2204	response regulator
LQ335_RS01050	COG2032	superoxide dismutase activity
LQ335_RS01055	COG2032	superoxide dismutase activity
LQ335_RS01065	COG0183	Belongs to the thiolase family
LQ335_RS01100	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
LQ335_RS01105	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
LQ335_RS01125	COG0798	PFAM Bile acid sodium symporter
LQ335_RS01145	COG0431	NADPH-dependent FMN reductase
LQ335_RS01175	COG2837	iron assimilation
LQ335_RS01195	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
LQ335_RS01205	COG2197	response regulator
LQ335_RS01210	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LQ335_RS01210	COG2205	protein histidine kinase activity
LQ335_RS01215	COG3474	cytochrome
LQ335_RS01225	COG1960	acyl-CoA dehydrogenase activity
LQ335_RS01235	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
LQ335_RS01245	COG0612	Peptidase, M16
LQ335_RS01255	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LQ335_RS01260	COG0596	Alpha beta hydrolase
LQ335_RS01270	COG0318	PFAM AMP-dependent synthetase and ligase
LQ335_RS01275	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LQ335_RS01285	COG1181	Belongs to the D-alanine--D-alanine ligase family
LQ335_RS01295	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
LQ335_RS01325	COG0339	signal peptide processing
LQ335_RS01345	COG2814	Major facilitator Superfamily
LQ335_RS01350	COG0583	DNA-binding transcription factor activity
LQ335_RS01355	COG0583	DNA-binding transcription factor activity
LQ335_RS01360	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
LQ335_RS01365	COG2224	Isocitrate lyase
LQ335_RS01370	COG3706	GGDEF domain
LQ335_RS01395	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
LQ335_RS01400	COG1960	acyl-CoA dehydrogenase activity
LQ335_RS01420	COG0697	spore germination
LQ335_RS01430	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
LQ335_RS01440	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LQ335_RS01445	COG1280	lysine exporter protein (LysE YggA)
LQ335_RS01450	COG1607	acyl-coa hydrolase
LQ335_RS01460	COG1902	pentaerythritol trinitrate reductase activity
LQ335_RS01475	COG1335	isochorismatase
LQ335_RS01480	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
LQ335_RS01490	COG1056	cytidyltransferase-related domain
LQ335_RS01490	COG1051	belongs to the nudix hydrolase family
LQ335_RS01495	COG1752	Esterase of the alpha-beta hydrolase superfamily
LQ335_RS01505	COG3800	Transcriptional regulator
LQ335_RS01505	COG1396	sequence-specific DNA binding
LQ335_RS01515	COG1960	acyl-CoA dehydrogenase activity
LQ335_RS01520	COG1024	Enoyl-CoA hydratase
LQ335_RS01525	COG1024	Enoyl-CoA hydratase
LQ335_RS01535	COG1764	response to oxidative stress
LQ335_RS01545	COG0659	secondary active sulfate transmembrane transporter activity
LQ335_RS01560	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LQ335_RS01580	COG3228	Belongs to the MtfA family
LQ335_RS01590	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
LQ335_RS01590	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
LQ335_RS01595	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
LQ335_RS01695	COG3237	CsbD-like
LQ335_RS01705	COG0180	Tryptophanyl-tRNA synthetase
LQ335_RS01730	COG0477	Major facilitator Superfamily
LQ335_RS01735	COG0697	spore germination
LQ335_RS01745	COG4206	TonB-dependent receptor
LQ335_RS01750	COG1136	(ABC) transporter
LQ335_RS01750	COG0577	efflux transmembrane transporter activity
LQ335_RS01760	COG1136	(ABC) transporter
LQ335_RS01770	COG4585	Histidine kinase
LQ335_RS01775	COG2197	response regulator
LQ335_RS01790	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
LQ335_RS01800	COG0628	permease
LQ335_RS01820	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LQ335_RS01835	COG5507	3-demethylubiquinone-9 3-methyltransferase
LQ335_RS01860	COG2814	Major facilitator Superfamily
LQ335_RS01865	COG0583	DNA-binding transcription factor activity
LQ335_RS01870	COG4807	Protein conserved in bacteria
LQ335_RS01880	COG4221	oxidoreductase activity
LQ335_RS01890	COG0018	arginyl-trna synthetase
LQ335_RS01960	COG2197	response regulator
LQ335_RS01965	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
LQ335_RS01970	COG0756	dUTP diphosphatase activity
LQ335_RS01985	COG2205	protein histidine kinase activity
LQ335_RS01995	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
LQ335_RS02000	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
LQ335_RS02015	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
LQ335_RS02020	COG0708	Exodeoxyribonuclease III
LQ335_RS02025	COG2223	nitrite transmembrane transporter activity
LQ335_RS02040	COG0739	heme binding
LQ335_RS02045	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
LQ335_RS02105	COG2234	aminopeptidase activity
LQ335_RS02115	COG4942	peptidase
LQ335_RS02120	COG0793	Belongs to the peptidase S41A family
LQ335_RS02130	COG2067	long-chain fatty acid transport protein
LQ335_RS02160	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
LQ335_RS02205	COG0109	protoheme IX farnesyltransferase activity
LQ335_RS02220	COG0358	DNA primase activity
LQ335_RS02225	COG1295	ribonuclease BN
LQ335_RS02240	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
LQ335_RS02250	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
LQ335_RS02255	COG0668	transmembrane transport
LQ335_RS02270	COG2133	pyrroloquinoline quinone binding
LQ335_RS02275	COG4682	membrane
LQ335_RS02285	COG0531	amino acid
LQ335_RS02295	COG1737	Transcriptional regulator
LQ335_RS02300	COG4948	Mandelate Racemase Muconate Lactonizing
LQ335_RS02325	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
LQ335_RS02350	COG5383	Protein conserved in bacteria
LQ335_RS02360	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
LQ335_RS02365	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
LQ335_RS02395	COG0778	Nitroreductase
LQ335_RS02400	COG2353	YceI-like domain
LQ335_RS02415	COG2375	cellular response to nickel ion
LQ335_RS02535	COG2267	carboxylic ester hydrolase activity
LQ335_RS02600	COG0488	(ABC) transporter
LQ335_RS02605	COG0583	DNA-binding transcription factor activity
LQ335_RS02615	COG2814	Major facilitator Superfamily
LQ335_RS02620	COG4943	cyclic-guanylate-specific phosphodiesterase activity
LQ335_RS02625	COG1113	amino acid transport
LQ335_RS02630	COG0741	lytic transglycosylase activity
LQ335_RS02660	COG2764	glyoxalase bleomycin resistance protein dioxygenase
LQ335_RS02670	COG5507	3-demethylubiquinone-9 3-methyltransferase
LQ335_RS02675	COG4941	Belongs to the sigma-70 factor family
LQ335_RS02705	COG3275	phosphorelay sensor kinase activity
LQ335_RS02710	COG3279	Response regulator of the LytR AlgR family
LQ335_RS02730	COG3590	peptidase
LQ335_RS02735	COG5001	Diguanylate cyclase
LQ335_RS02740	COG0583	DNA-binding transcription factor activity
LQ335_RS02750	COG3384	dioxygenase
LQ335_RS02755	COG0025	NhaP-type Na H and K H
LQ335_RS02810	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LQ335_RS02825	COG5002	protein histidine kinase activity
LQ335_RS02840	COG2813	Specifically methylates the guanine in position
LQ335_RS02845	COG1187	pseudouridine synthase activity
LQ335_RS02850	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LQ335_RS02860	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
LQ335_RS02865	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LQ335_RS02880	COG0583	DNA-binding transcription factor activity
LQ335_RS02885	COG2226	methyltransferase
LQ335_RS02910	COG1956	GAF domain-containing protein
LQ335_RS02915	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
LQ335_RS02920	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LQ335_RS02925	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LQ335_RS02930	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LQ335_RS02930	COG0785	Cytochrome C biogenesis protein
LQ335_RS02935	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LQ335_RS02940	COG0745	RESPONSE REGULATOR receiver
LQ335_RS02945	COG5002	protein histidine kinase activity
LQ335_RS02950	COG2205	protein histidine kinase activity
LQ335_RS02955	COG0745	RESPONSE REGULATOR receiver
LQ335_RS02960	COG0367	asparagine synthase
LQ335_RS02970	COG0720	synthase
LQ335_RS02975	COG4206	TonB-dependent receptor
LQ335_RS02985	COG0513	Belongs to the DEAD box helicase family
LQ335_RS03000	COG0625	glutathione transferase activity
LQ335_RS03040	COG0626	cystathionine gamma-synthase activity
LQ335_RS03065	COG1215	transferase activity, transferring glycosyl groups
LQ335_RS03085	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
LQ335_RS03135	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
LQ335_RS03145	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LQ335_RS03150	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
LQ335_RS03170	COG1216	Glycosyl transferase, family 2
LQ335_RS03185	COG1127	ABC transporter
LQ335_RS03190	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
LQ335_RS03205	COG0442	prolyl-tRNA aminoacylation
LQ335_RS03215	COG1183	phosphatidylcholine synthase activity
LQ335_RS03235	COG0525	valine-tRNA ligase activity
LQ335_RS03245	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
LQ335_RS03255	COG0795	lipopolysaccharide-transporting ATPase activity
LQ335_RS03265	COG4974	Belongs to the 'phage' integrase family
LQ335_RS03280	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LQ335_RS03280	COG0047	phosphoribosylformylglycinamidine synthase activity
LQ335_RS03285	COG5295	Hep Hag repeat protein
LQ335_RS03290	COG1404	Belongs to the peptidase S8 family
LQ335_RS03295	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
LQ335_RS03300	COG1459	type II secretion system
LQ335_RS03305	COG2165	general secretion pathway protein
LQ335_RS03310	COG4970	Tfp pilus assembly protein FimT
LQ335_RS03315	COG2165	general secretion pathway protein
LQ335_RS03320	COG4795	General secretion pathway protein
LQ335_RS03325	COG3156	type II secretion system protein K
LQ335_RS03330	COG3166	PFAM Fimbrial assembly family protein
LQ335_RS03345	COG1450	Type ii and iii secretion system protein
LQ335_RS03370	COG3539	Fimbrial protein
LQ335_RS03390	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
LQ335_RS03400	COG1215	transferase activity, transferring glycosyl groups
LQ335_RS03415	COG2252	PERMEase
LQ335_RS03420	COG0488	(ABC) transporter
LQ335_RS03430	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
LQ335_RS03450	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
LQ335_RS03455	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LQ335_RS03455	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LQ335_RS03485	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
LQ335_RS03490	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
LQ335_RS03500	COG3152	Membrane
LQ335_RS03525	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
LQ335_RS03525	COG2755	lipolytic protein G-D-S-L family
LQ335_RS03530	COG0277	FAD linked oxidase domain protein
LQ335_RS03535	COG1988	membrane-bound metal-dependent
LQ335_RS03570	COG2001	Belongs to the MraZ family
LQ335_RS03575	COG0275	rRNA processing
LQ335_RS03580	COG3116	cell division
LQ335_RS03590	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
LQ335_RS03595	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
LQ335_RS03610	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
LQ335_RS03615	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
LQ335_RS03620	COG1181	Belongs to the D-alanine--D-alanine ligase family
LQ335_RS03625	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
LQ335_RS03635	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
LQ335_RS03640	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
LQ335_RS03650	COG0739	heme binding
LQ335_RS03655	COG0653	protein targeting
LQ335_RS03660	COG0494	nUDIX hydrolase
LQ335_RS03670	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
LQ335_RS03680	COG3275	phosphorelay sensor kinase activity
LQ335_RS03690	COG0402	S-adenosylhomocysteine deaminase activity
LQ335_RS03705	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
LQ335_RS03710	COG3773	Cell wall hydrolase
LQ335_RS03710	COG3409	Peptidoglycan-binding domain 1 protein
LQ335_RS03720	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
LQ335_RS03730	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
LQ335_RS03735	COG1607	acyl-coa hydrolase
LQ335_RS03740	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
LQ335_RS03760	COG4106	trans-aconitate 2-methyltransferase activity
LQ335_RS03765	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LQ335_RS03775	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LQ335_RS03780	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
LQ335_RS03785	COG0667	Aldo Keto reductase
LQ335_RS03795	COG4771	TonB-dependent receptor
LQ335_RS03810	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
LQ335_RS03815	COG4181	ATPase activity
LQ335_RS03830	COG0642	Histidine kinase
LQ335_RS03840	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
LQ335_RS03845	COG0861	Integral membrane protein TerC family
LQ335_RS03850	COG2814	Major facilitator Superfamily
LQ335_RS03865	COG1704	LemA family
LQ335_RS03880	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
LQ335_RS03885	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
LQ335_RS03895	COG3738	Protein conserved in bacteria
LQ335_RS03900	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
LQ335_RS03905	COG2967	ApaG domain
LQ335_RS03910	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
LQ335_RS03915	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
LQ335_RS03920	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
LQ335_RS03925	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
LQ335_RS03935	COG2096	Adenosyltransferase
LQ335_RS03945	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LQ335_RS03950	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LQ335_RS03955	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
LQ335_RS03960	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
LQ335_RS03980	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
LQ335_RS03990	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LQ335_RS04005	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
LQ335_RS04010	COG0583	DNA-binding transcription factor activity
LQ335_RS04015	COG3634	alkyl hydroperoxide reductase activity
LQ335_RS04035	COG0583	DNA-binding transcription factor activity
LQ335_RS04070	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
LQ335_RS04095	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
LQ335_RS04110	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
LQ335_RS04115	COG1404	Belongs to the peptidase S8 family
LQ335_RS04135	COG1295	ribonuclease BN
LQ335_RS04140	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LQ335_RS04155	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
LQ335_RS04160	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
LQ335_RS04175	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
LQ335_RS04185	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
LQ335_RS04190	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
LQ335_RS04195	COG0193	aminoacyl-tRNA hydrolase activity
LQ335_RS04205	COG0012	GTP binding
LQ335_RS04210	COG4206	TonB-dependent receptor
LQ335_RS04215	COG4242	Belongs to the peptidase S51 family
LQ335_RS04240	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
LQ335_RS04255	COG0250	Participates in transcription elongation, termination and antitermination
LQ335_RS04260	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
LQ335_RS04265	COG0081	regulation of translation
LQ335_RS04270	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
LQ335_RS04275	COG0222	ribosome binding
LQ335_RS04280	COG0085	RNA polymerase activity
LQ335_RS04285	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
LQ335_RS04290	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
LQ335_RS04295	COG0049	tRNA binding
LQ335_RS04300	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
LQ335_RS04305	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
LQ335_RS04310	COG0051	transcription antitermination factor activity, RNA binding
LQ335_RS04315	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
LQ335_RS04320	COG0088	Forms part of the polypeptide exit tunnel
LQ335_RS04325	COG0089	rRNA binding
LQ335_RS04330	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
LQ335_RS04335	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
LQ335_RS04340	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
LQ335_RS04345	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
LQ335_RS04350	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
LQ335_RS04355	COG0255	Belongs to the universal ribosomal protein uL29 family
LQ335_RS04360	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
LQ335_RS04365	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
LQ335_RS04370	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
LQ335_RS04375	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
LQ335_RS04380	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
LQ335_RS04385	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
LQ335_RS04390	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
LQ335_RS04395	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
LQ335_RS04400	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
LQ335_RS04405	COG1841	ribosomal large subunit assembly
LQ335_RS04410	COG0200	Binds to the 23S rRNA
LQ335_RS04415	COG0201	protein transport
LQ335_RS04420	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
LQ335_RS04425	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
LQ335_RS04430	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
LQ335_RS04435	COG0202	RNA polymerase activity
LQ335_RS04440	COG0203	ribosomal protein L17
LQ335_RS04455	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
LQ335_RS04465	COG0154	amidase activity
LQ335_RS04480	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
LQ335_RS04485	COG0039	L-malate dehydrogenase activity
LQ335_RS04490	COG0564	pseudouridine synthase activity
LQ335_RS04495	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
LQ335_RS04510	COG0625	glutathione transferase activity
LQ335_RS04520	COG0446	pyridine nucleotide-disulphide oxidoreductase
LQ335_RS04520	COG1902	pentaerythritol trinitrate reductase activity
LQ335_RS04525	COG2364	Membrane
LQ335_RS04530	COG0604	alcohol dehydrogenase
LQ335_RS04545	COG1187	pseudouridine synthase activity
LQ335_RS04565	COG1063	alcohol dehydrogenase
LQ335_RS04575	COG0588	phosphoglycerate mutase activity
LQ335_RS04580	COG0285	dihydrofolate synthase activity
LQ335_RS04600	COG2833	Protein of unknown function (DUF455)
LQ335_RS04610	COG3291	Pkd domain containing protein
LQ335_RS04615	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
LQ335_RS04620	COG0671	phosphoesterase, PA-phosphatase related
LQ335_RS04625	COG0438	transferase activity, transferring glycosyl groups
LQ335_RS04635	COG0248	Ppx GppA phosphatase
LQ335_RS04640	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
LQ335_RS04655	COG4783	chaperone-mediated protein folding
LQ335_RS04670	COG0473	3-isopropylmalate dehydrogenase activity
LQ335_RS04725	COG0544	peptidyl-prolyl cis-trans isomerase activity
LQ335_RS04730	COG0740	serine-type endopeptidase activity
LQ335_RS04735	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
LQ335_RS04775	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
LQ335_RS04780	COG3942	CHAP domain
LQ335_RS04780	COG1388	LysM domain
LQ335_RS04785	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LQ335_RS04795	COG0328	RNA-DNA hybrid ribonuclease activity
LQ335_RS04800	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
LQ335_RS04805	COG0631	protein serine/threonine phosphatase activity
LQ335_RS04820	COG0859	PFAM glycosyl transferase family 9
LQ335_RS04825	COG3642	lipopolysaccharide core region biosynthetic process
LQ335_RS04830	COG1234	tRNA 3'-trailer cleavage
LQ335_RS04840	COG2076	Multidrug Resistance protein
LQ335_RS04865	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
LQ335_RS04870	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
LQ335_RS04880	COG0537	adenosine 5'-monophosphoramidase activity
LQ335_RS04900	COG0714	Associated with various cellular activities
LQ335_RS04915	COG1399	metal-binding, possibly nucleic acid-binding protein
LQ335_RS04920	COG0333	Belongs to the bacterial ribosomal protein bL32 family
LQ335_RS04925	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LQ335_RS04935	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
LQ335_RS04940	COG1028	Short-chain dehydrogenase reductase Sdr
LQ335_RS04950	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
LQ335_RS04955	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
LQ335_RS04960	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
LQ335_RS04965	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
LQ335_RS05000	COG1196	nuclear chromosome segregation
LQ335_RS05105	COG4774	siderophore transport
LQ335_RS05115	COG2223	nitrite transmembrane transporter activity
LQ335_RS05130	COG2226	methyltransferase
LQ335_RS05145	COG0583	DNA-binding transcription factor activity
LQ335_RS05150	COG0477	Major facilitator Superfamily
LQ335_RS05185	COG0583	DNA-binding transcription factor activity
LQ335_RS05195	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
LQ335_RS05210	COG0667	Aldo Keto reductase
LQ335_RS05230	COG2818	Glycosylase
LQ335_RS05235	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
LQ335_RS05240	COG1678	Uncharacterized ACR, COG1678
LQ335_RS05245	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
LQ335_RS05250	COG0540	Belongs to the ATCase OTCase family
LQ335_RS05255	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
LQ335_RS05275	COG2239	Acts as a magnesium transporter
LQ335_RS05280	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
LQ335_RS05295	COG1660	Displays ATPase and GTPase activities
LQ335_RS05300	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
LQ335_RS05305	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LQ335_RS05310	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
LQ335_RS05320	COG1137	ATPase activity
LQ335_RS05335	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
LQ335_RS05350	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
LQ335_RS05370	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
LQ335_RS05390	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
LQ335_RS05400	COG0628	permease
LQ335_RS05410	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
LQ335_RS05420	COG2261	transglycosylase associated protein
LQ335_RS05430	COG1555	photosystem II stabilization
LQ335_RS05450	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
LQ335_RS05455	COG1477	protein flavinylation
LQ335_RS05475	COG4771	TonB-dependent receptor
LQ335_RS05485	COG3128	pkhd-type hydroxylase
LQ335_RS05495	COG4774	siderophore transport
LQ335_RS05505	COG2146	nitrite reductase [NAD(P)H] activity
LQ335_RS05520	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
LQ335_RS05525	COG0719	Fe-S assembly protein
LQ335_RS05530	COG0396	ATPase activity
LQ335_RS05535	COG3755	Protein conserved in bacteria
LQ335_RS05540	COG0719	Fe-S assembly protein
LQ335_RS05545	COG1959	2 iron, 2 sulfur cluster binding
LQ335_RS05555	COG0693	protein deglycase activity
LQ335_RS05580	COG1764	response to oxidative stress
LQ335_RS05585	COG0384	phenazine biosynthesis protein PhzF
LQ335_RS05590	COG0384	phenazine biosynthesis protein PhzF
LQ335_RS05595	COG0527	aspartate kinase activity
LQ335_RS05605	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
LQ335_RS05625	COG0142	geranyltranstransferase activity
LQ335_RS05630	COG0366	Alpha amylase catalytic
LQ335_RS05640	COG1082	Xylose isomerase domain protein TIM barrel
LQ335_RS05650	COG2211	Major facilitator Superfamily
LQ335_RS05650	COG2190	(PTS) system
LQ335_RS05680	COG0629	single-stranded DNA binding
LQ335_RS05685	COG0583	DNA-binding transcription factor activity
LQ335_RS05720	COG2010	Cytochrome c
LQ335_RS05730	COG0673	inositol 2-dehydrogenase activity
LQ335_RS05735	COG2211	Major facilitator Superfamily
LQ335_RS05745	COG1609	Transcriptional regulator
LQ335_RS05785	COG0640	Transcriptional regulator
LQ335_RS05800	COG3655	Transcriptional regulator
LQ335_RS05805	COG1253	flavin adenine dinucleotide binding
LQ335_RS05810	COG1408	metallophosphoesterase
LQ335_RS05820	COG0477	Major facilitator Superfamily
LQ335_RS05845	COG0579	oxidoreductase
LQ335_RS05870	COG3104	oligopeptide transport
LQ335_RS05880	COG1297	OPT oligopeptide transporter protein
LQ335_RS05885	COG0823	Involved in the tonB-independent uptake of proteins
LQ335_RS05885	COG1506	peptidase
LQ335_RS05900	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
LQ335_RS05905	COG2894	cell division
LQ335_RS05910	COG0850	regulation of cytokinetic process
LQ335_RS05920	COG4585	Histidine kinase
LQ335_RS05925	COG2197	response regulator
LQ335_RS05965	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
LQ335_RS05980	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
LQ335_RS05990	COG1595	DNA-templated transcription, initiation
LQ335_RS06000	COG1946	Acyl-CoA thioesterase
LQ335_RS06020	COG0824	Thioesterase
LQ335_RS06025	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
LQ335_RS06030	COG0261	This protein binds to 23S rRNA in the presence of protein L20
LQ335_RS06035	COG0211	Belongs to the bacterial ribosomal protein bL27 family
LQ335_RS06040	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
LQ335_RS06045	COG0268	Binds directly to 16S ribosomal RNA
LQ335_RS06050	COG0728	peptidoglycan biosynthetic process
LQ335_RS06055	COG0196	riboflavin kinase activity
LQ335_RS06060	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
LQ335_RS06070	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
LQ335_RS06095	COG4206	TonB-dependent receptor
LQ335_RS06115	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LQ335_RS06160	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
LQ335_RS06165	COG1845	cytochrome c oxidase, subunit III
LQ335_RS06170	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
LQ335_RS06185	COG0326	Molecular chaperone. Has ATPase activity
LQ335_RS06205	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
LQ335_RS06220	COG0228	four-way junction DNA binding
LQ335_RS06225	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
LQ335_RS06230	COG0336	Belongs to the RNA methyltransferase TrmD family
LQ335_RS06235	COG0335	large ribosomal subunit rRNA binding
LQ335_RS06255	COG0534	Mate efflux family protein
LQ335_RS06270	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
LQ335_RS06290	COG2831	hemolysin activation secretion protein
LQ335_RS06295	COG3210	domain, Protein
LQ335_RS06320	COG0840	transmembrane signaling receptor activity
LQ335_RS06325	COG3134	Outer membrane lipoprotein
LQ335_RS06345	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LQ335_RS06365	COG0024	Methionine aminopeptidase
LQ335_RS06390	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
LQ335_RS06405	COG2076	Multidrug Resistance protein
LQ335_RS06415	COG1647	Serine aminopeptidase, S33
LQ335_RS06440	COG2814	Major facilitator Superfamily
LQ335_RS06445	COG3706	GGDEF domain
LQ335_RS06465	COG0588	phosphoglycerate mutase activity
LQ335_RS06475	COG3590	peptidase
LQ335_RS06485	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
LQ335_RS06495	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
LQ335_RS06500	COG0745	RESPONSE REGULATOR receiver
LQ335_RS06505	COG2205	protein histidine kinase activity
LQ335_RS06510	COG4452	Inner membrane protein CreD
LQ335_RS06525	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
LQ335_RS06530	COG0735	belongs to the Fur family
LQ335_RS06570	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
LQ335_RS06615	COG5001	Diguanylate cyclase
LQ335_RS06615	COG5002	protein histidine kinase activity
LQ335_RS06625	COG1187	pseudouridine synthase activity
LQ335_RS06635	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
LQ335_RS06665	COG1132	(ABC) transporter
LQ335_RS06710	COG1695	Transcriptional regulator
LQ335_RS06730	COG1981	membrane
LQ335_RS06735	COG0825	malonyl-CoA metabolic process
LQ335_RS06755	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
LQ335_RS06760	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
LQ335_RS06775	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LQ335_RS06780	COG0750	zinc metalloprotease
LQ335_RS06785	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
LQ335_RS06790	COG0575	Belongs to the CDS family
LQ335_RS06795	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
LQ335_RS06800	COG0233	cytoplasmic translational termination
LQ335_RS06805	COG0528	UMP kinase activity
LQ335_RS06815	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
LQ335_RS06820	COG0052	Belongs to the universal ribosomal protein uS2 family
LQ335_RS06840	COG3188	usher protein
LQ335_RS06860	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
LQ335_RS06875	COG1393	Belongs to the ArsC family
LQ335_RS06880	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LQ335_RS06890	COG0367	asparagine synthase
LQ335_RS06895	COG0475	glutathione-regulated potassium exporter activity
LQ335_RS06930	COG1566	PFAM secretion protein HlyD family protein
LQ335_RS06935	COG2814	Major facilitator Superfamily
LQ335_RS06945	COG0583	DNA-binding transcription factor activity
LQ335_RS06965	COG0557	exoribonuclease II activity
LQ335_RS06975	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LQ335_RS06980	COG1538	Outer membrane efflux protein
LQ335_RS06985	COG0577	efflux transmembrane transporter activity
LQ335_RS06985	COG1136	(ABC) transporter
LQ335_RS06990	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LQ335_RS07015	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
LQ335_RS07020	COG2259	Doxx family
LQ335_RS07030	COG3220	belongs to the UPF0276 family
LQ335_RS07040	COG0704	Plays a role in the regulation of phosphate uptake
LQ335_RS07050	COG0581	inorganic phosphate transmembrane transporter activity
LQ335_RS07055	COG0573	inorganic phosphate transmembrane transporter activity
LQ335_RS07060	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
LQ335_RS07065	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
LQ335_RS07075	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
LQ335_RS07085	COG1024	Enoyl-CoA hydratase
LQ335_RS07095	COG0494	nUDIX hydrolase
LQ335_RS07115	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
LQ335_RS07115	COG0116	Belongs to the methyltransferase superfamily
LQ335_RS07140	COG2733	membrane
LQ335_RS07150	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
LQ335_RS07155	COG1012	belongs to the aldehyde dehydrogenase family
LQ335_RS07160	COG0477	Major facilitator Superfamily
LQ335_RS07165	COG2703	oxygen carrier activity
LQ335_RS07190	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LQ335_RS07200	COG0174	glutamine synthetase
LQ335_RS07210	COG2072	flavoprotein involved in K transport
LQ335_RS07215	COG3842	ATPase activity
LQ335_RS07220	COG1176	ABC-type spermidine putrescine transport system, permease component I
LQ335_RS07225	COG1177	transmembrane transport
LQ335_RS07230	COG1012	belongs to the aldehyde dehydrogenase family
LQ335_RS07245	COG4535	Mg2 and Co2 transporter CorC
LQ335_RS07255	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
LQ335_RS07260	COG1702	phosphate starvation-inducible protein PhoH
LQ335_RS07270	COG1131	(ABC) transporter
LQ335_RS07275	COG0842	Transport permease protein
LQ335_RS07280	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
LQ335_RS07295	COG0741	lytic transglycosylase activity
LQ335_RS07300	COG0723	plastoquinol--plastocyanin reductase activity
LQ335_RS07305	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
LQ335_RS07310	COG2857	Cytochrome c1
LQ335_RS07315	COG0625	glutathione transferase activity
LQ335_RS07320	COG2969	positive regulation of protein catabolic process
LQ335_RS07355	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
LQ335_RS07365	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
LQ335_RS07380	COG1611	Belongs to the LOG family
LQ335_RS07425	COG0556	nucleotide-excision repair
LQ335_RS07455	COG0745	RESPONSE REGULATOR receiver
LQ335_RS07465	COG2333	competence protein COMEC
LQ335_RS07465	COG0658	competence protein
LQ335_RS07470	COG0811	peptide transport
LQ335_RS07485	COG1663	tetraacyldisaccharide 4'-kinase activity
LQ335_RS07490	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
LQ335_RS07495	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LQ335_RS07505	COG0322	excinuclease ABC activity
LQ335_RS07570	COG1136	(ABC) transporter
LQ335_RS07570	COG0577	efflux transmembrane transporter activity
LQ335_RS07600	COG1397	ADP-ribosylglycohydrolase
LQ335_RS07615	COG4977	sequence-specific DNA binding
LQ335_RS07615	COG1917	Cupin 2, conserved barrel domain protein
LQ335_RS07620	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
LQ335_RS07640	COG0348	domain, Protein
LQ335_RS07655	COG0635	Involved in the biosynthesis of porphyrin-containing compound
LQ335_RS07670	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
LQ335_RS07675	COG0069	glutamate synthase activity
LQ335_RS07680	COG0456	acetyltransferase
LQ335_RS07700	COG1054	Belongs to the UPF0176 family
LQ335_RS07705	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LQ335_RS07720	COG1253	flavin adenine dinucleotide binding
LQ335_RS07730	COG0306	phosphate transporter
LQ335_RS07740	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LQ335_RS07755	COG0504	CTP synthase activity
LQ335_RS07760	COG2877	3-deoxy-8-phosphooctulonate synthase activity
LQ335_RS07775	COG0148	phosphopyruvate hydratase activity
LQ335_RS07780	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
LQ335_RS07785	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
LQ335_RS07800	COG2840	Smr protein MutS2
LQ335_RS07805	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
LQ335_RS07810	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
LQ335_RS07830	COG1534	Rna-binding protein
LQ335_RS07835	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
LQ335_RS07840	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LQ335_RS07850	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
LQ335_RS07855	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
LQ335_RS07860	COG1923	regulation of RNA biosynthetic process
LQ335_RS07865	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
LQ335_RS07870	COG1546	Belongs to the CinA family
LQ335_RS07875	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
LQ335_RS07880	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
LQ335_RS07885	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
LQ335_RS07890	COG2137	regulation of response to DNA damage stimulus
LQ335_RS07895	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
LQ335_RS07900	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
LQ335_RS07945	COG3540	Alkaline phosphatase
LQ335_RS07960	COG3258	Cytochrome c
LQ335_RS07975	COG2223	nitrite transmembrane transporter activity
LQ335_RS07980	COG1741	Belongs to the pirin family
LQ335_RS07985	COG0583	DNA-binding transcription factor activity
LQ335_RS08010	COG0351	phosphomethylpyrimidine kinase
LQ335_RS08010	COG0352	thiamine-phosphate diphosphorylase activity
LQ335_RS08025	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
LQ335_RS08030	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
LQ335_RS08040	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LQ335_RS08050	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
LQ335_RS08055	COG0477	Major facilitator Superfamily
LQ335_RS08065	COG0617	tRNA 3'-terminal CCA addition
LQ335_RS08075	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
LQ335_RS08080	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
LQ335_RS08085	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
LQ335_RS08090	COG0166	Belongs to the GPI family
LQ335_RS08095	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
LQ335_RS08105	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
LQ335_RS08110	COG0671	phosphoesterase, PA-phosphatase related
LQ335_RS08120	COG0800	Aldolase
LQ335_RS08125	COG0129	dihydroxy-acid dehydratase activity
LQ335_RS08135	COG0837	glucose binding
LQ335_RS08140	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
LQ335_RS08160	COG2009	succinate dehydrogenase
LQ335_RS08165	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
LQ335_RS08170	COG1053	succinate dehydrogenase
LQ335_RS08190	COG4591	ABC-type transport system involved in lipoprotein release permease component
LQ335_RS08205	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
LQ335_RS08215	COG0552	protein localization to endoplasmic reticulum
LQ335_RS08230	COG0742	ribosomal rna small subunit methyltransferase
LQ335_RS08235	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
LQ335_RS08245	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
LQ335_RS08250	COG0405	Gamma-glutamyltransferase
LQ335_RS08255	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LQ335_RS08265	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
LQ335_RS08285	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
LQ335_RS08290	COG0415	Belongs to the DNA photolyase family
LQ335_RS08295	COG2885	chlorophyll binding
LQ335_RS08300	COG0583	DNA-binding transcription factor activity
LQ335_RS08360	COG2124	cytochrome p450
LQ335_RS08390	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
LQ335_RS08405	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LQ335_RS08410	COG0735	belongs to the Fur family
LQ335_RS08420	COG0583	DNA-binding transcription factor activity
LQ335_RS08425	COG0497	DNA recombination
LQ335_RS08430	COG1420	regulation of RNA biosynthetic process
LQ335_RS08435	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
LQ335_RS08440	COG0443	Heat shock 70 kDa protein
LQ335_RS08445	COG0484	heat shock protein binding
LQ335_RS08450	COG2207	Transcriptional regulator
LQ335_RS08455	COG2223	nitrite transmembrane transporter activity
LQ335_RS08460	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
LQ335_RS08465	COG0287	Prephenate dehydrogenase
LQ335_RS08465	COG1605	Chorismate mutase
LQ335_RS08475	COG1132	(ABC) transporter
LQ335_RS08495	COG5001	Diguanylate cyclase
LQ335_RS08495	COG2203	Gaf domain
LQ335_RS08495	COG3706	GGDEF domain
LQ335_RS08495	COG4251	negative regulation of phosphorylation
LQ335_RS08505	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
LQ335_RS08510	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
LQ335_RS08515	COG0343	queuine tRNA-ribosyltransferase activity
LQ335_RS08520	COG1862	Preprotein translocase
LQ335_RS08530	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LQ335_RS08535	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
LQ335_RS08545	COG2081	HI0933 family
LQ335_RS08550	COG4681	YaeQ
LQ335_RS08555	COG0564	pseudouridine synthase activity
LQ335_RS08565	COG1278	Cold shock
LQ335_RS08570	COG0625	glutathione transferase activity
LQ335_RS08575	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
LQ335_RS08585	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
LQ335_RS08590	COG0513	Belongs to the DEAD box helicase family
LQ335_RS08600	COG0583	DNA-binding transcription factor activity
LQ335_RS08605	COG0488	(ABC) transporter
LQ335_RS08630	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LQ335_RS08645	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LQ335_RS08650	COG2957	Belongs to the agmatine deiminase family
LQ335_RS08660	COG0257	Belongs to the bacterial ribosomal protein bL36 family
LQ335_RS08665	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
LQ335_RS08675	COG0776	regulation of translation
LQ335_RS08685	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
LQ335_RS08700	COG1210	Utp--glucose-1-phosphate uridylyltransferase
LQ335_RS08705	COG0183	Belongs to the thiolase family
LQ335_RS08710	COG1024	Enoyl-CoA hydratase
LQ335_RS08710	COG1250	3-hydroxyacyl-CoA dehydrogenase
LQ335_RS08720	COG0105	UTP biosynthetic process
LQ335_RS08725	COG0820	rRNA (adenine-C2-)-methyltransferase activity
LQ335_RS08730	COG0457	Tetratricopeptide repeat
LQ335_RS08730	COG0859	PFAM glycosyl transferase family 9
LQ335_RS08735	COG1426	Protein conserved in bacteria
LQ335_RS08740	COG2976	Protein conserved in bacteria
LQ335_RS08745	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LQ335_RS08750	COG1160	GTP binding
LQ335_RS08770	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
LQ335_RS08775	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
LQ335_RS08775	COG0475	glutathione-regulated potassium exporter activity
LQ335_RS08795	COG0519	Catalyzes the synthesis of GMP from XMP
LQ335_RS08795	COG0518	GMP synthase (glutamine-hydrolyzing) activity
LQ335_RS08800	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
LQ335_RS08820	COG0583	DNA-binding transcription factor activity
LQ335_RS08830	COG1028	Short-chain dehydrogenase reductase Sdr
LQ335_RS08855	COG1028	Short-chain dehydrogenase reductase Sdr
LQ335_RS08865	COG0640	Transcriptional regulator
LQ335_RS08905	COG4206	TonB-dependent receptor
LQ335_RS08910	COG0431	NADPH-dependent FMN reductase
LQ335_RS08920	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LQ335_RS08925	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LQ335_RS08930	COG1473	amidohydrolase
LQ335_RS08950	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LQ335_RS08975	COG4943	cyclic-guanylate-specific phosphodiesterase activity
LQ335_RS08980	COG1028	Short-chain dehydrogenase reductase Sdr
LQ335_RS08995	COG1309	transcriptional regulator
LQ335_RS09010	COG0697	spore germination
LQ335_RS09015	COG0812	UDP-N-acetylmuramate dehydrogenase activity
LQ335_RS09020	COG0167	dihydroorotate dehydrogenase activity
LQ335_RS09035	COG1028	Short-chain dehydrogenase reductase Sdr
LQ335_RS09040	COG1012	belongs to the aldehyde dehydrogenase family
LQ335_RS09065	COG0745	RESPONSE REGULATOR receiver
LQ335_RS09070	COG4191	Histidine kinase
LQ335_RS09070	COG0784	Response regulator, receiver
LQ335_RS09075	COG4999	Histidine kinase
LQ335_RS09075	COG3437	response regulator, receiver
LQ335_RS09075	COG2205	protein histidine kinase activity
LQ335_RS09075	COG3850	Histidine kinase
LQ335_RS09080	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
LQ335_RS09100	COG0640	Transcriptional regulator
LQ335_RS09155	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LQ335_RS09160	COG0124	histidyl-tRNA synthetase
LQ335_RS09170	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
LQ335_RS09175	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
LQ335_RS09180	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
LQ335_RS09185	COG0131	Imidazoleglycerol-phosphate dehydratase
LQ335_RS09185	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
LQ335_RS09190	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
LQ335_RS09195	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
LQ335_RS09200	COG0107	imidazoleglycerol-phosphate synthase activity
LQ335_RS09205	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
LQ335_RS09205	COG0140	phosphoribosyl-ATP diphosphatase activity
LQ335_RS09225	COG1446	asparaginase
LQ335_RS09230	COG3142	Participates in the control of copper homeostasis
LQ335_RS09235	COG4206	TonB-dependent receptor
LQ335_RS09240	COG2217	Heavy metal translocating P-type atpase
LQ335_RS09245	COG0789	Transcriptional regulator
LQ335_RS09270	COG3537	Alpha-1,2-mannosidase
LQ335_RS09275	COG1609	Transcriptional regulator
LQ335_RS09285	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LQ335_RS09300	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
LQ335_RS09305	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
LQ335_RS09310	COG0235	Class ii aldolase
LQ335_RS09325	COG0531	amino acid
LQ335_RS09330	COG0531	amino acid
LQ335_RS09340	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
LQ335_RS09345	COG0277	FAD linked oxidase domain protein
LQ335_RS09360	COG2205	protein histidine kinase activity
LQ335_RS09365	COG0745	RESPONSE REGULATOR receiver
LQ335_RS09370	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LQ335_RS09390	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
LQ335_RS09410	COG1024	Enoyl-CoA hydratase
LQ335_RS09435	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
LQ335_RS09440	COG0505	Belongs to the CarA family
LQ335_RS09445	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
LQ335_RS09450	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
LQ335_RS09465	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
LQ335_RS09470	COG4676	Protein conserved in bacteria
LQ335_RS09485	COG1012	belongs to the aldehyde dehydrogenase family
LQ335_RS09505	COG0784	Response regulator, receiver
LQ335_RS09505	COG2198	Histidine kinase
LQ335_RS09505	COG2205	protein histidine kinase activity
LQ335_RS09510	COG1024	Enoyl-CoA hydratase
LQ335_RS09515	COG0318	PFAM AMP-dependent synthetase and ligase
LQ335_RS09520	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
LQ335_RS09525	COG1012	belongs to the aldehyde dehydrogenase family
LQ335_RS09530	COG1309	transcriptional regulator
LQ335_RS09535	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
LQ335_RS09580	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
LQ335_RS09590	COG0840	transmembrane signaling receptor activity
LQ335_RS09605	COG0840	transmembrane signaling receptor activity
LQ335_RS09615	COG0835	chemotaxis
LQ335_RS09620	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
LQ335_RS09625	COG0840	transmembrane signaling receptor activity
LQ335_RS09635	COG0745	RESPONSE REGULATOR receiver
LQ335_RS09645	COG0835	chemotaxis
LQ335_RS09655	COG1360	Flagellar Motor Protein
LQ335_RS09660	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
LQ335_RS09665	COG0643	Histidine kinase
LQ335_RS09665	COG0784	Response regulator, receiver
LQ335_RS09665	COG2198	Histidine kinase
LQ335_RS09670	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
LQ335_RS09695	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
LQ335_RS09700	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
LQ335_RS09715	COG1987	bacterial-type flagellum assembly
LQ335_RS09725	COG3190	flagellar
LQ335_RS09775	COG1677	Flagellar hook-basal body complex protein FliE
LQ335_RS09800	COG2197	response regulator
LQ335_RS09820	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
LQ335_RS09830	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
LQ335_RS09845	COG1256	bacterial-type flagellum assembly
LQ335_RS09860	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
LQ335_RS09870	COG4787	bacterial-type flagellum-dependent cell motility
LQ335_RS09890	COG1815	bacterial-type flagellum-dependent cell motility
LQ335_RS09895	COG0835	chemotaxis
LQ335_RS09895	COG0784	Response regulator, receiver
LQ335_RS09915	COG5002	protein histidine kinase activity
LQ335_RS09955	COG2915	High frequency lysogenization protein hflD homolog
LQ335_RS09960	COG0482	sulfurtransferase activity
LQ335_RS09975	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
LQ335_RS09985	COG0542	response to heat
LQ335_RS10025	COG0492	ferredoxin-NADP+ reductase activity
LQ335_RS10030	COG1674	ftsk spoiiie
LQ335_RS10045	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
LQ335_RS10065	COG2819	hydrolase of the alpha beta superfamily
LQ335_RS10075	COG4558	Periplasmic binding protein
LQ335_RS10080	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LQ335_RS10085	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
LQ335_RS10095	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
LQ335_RS10110	COG0784	Response regulator, receiver
LQ335_RS10110	COG5002	protein histidine kinase activity
LQ335_RS10140	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
LQ335_RS10150	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
LQ335_RS10165	COG1595	DNA-templated transcription, initiation
LQ335_RS10185	COG0784	Response regulator, receiver
LQ335_RS10190	COG4251	negative regulation of phosphorylation
LQ335_RS10205	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
LQ335_RS10215	COG0454	-acetyltransferase
LQ335_RS10215	COG0456	acetyltransferase
LQ335_RS10220	COG0243	molybdopterin cofactor binding
LQ335_RS10225	COG0542	response to heat
LQ335_RS10230	COG0443	Heat shock 70 kDa protein
LQ335_RS10235	COG1294	oxidase, subunit
LQ335_RS10240	COG1271	oxidase subunit
LQ335_RS10245	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
LQ335_RS10250	COG0243	molybdopterin cofactor binding
LQ335_RS10255	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
LQ335_RS10260	COG0315	cyclic pyranopterin monophosphate synthase activity
LQ335_RS10260	COG0521	Mo-molybdopterin cofactor biosynthetic process
LQ335_RS10275	COG0314	molybdopterin synthase activity
LQ335_RS10280	COG0746	molybdenum cofactor guanylyltransferase activity
LQ335_RS10290	COG0725	ABC transporter, periplasmic molybdate-binding protein
LQ335_RS10295	COG4149	molybdate abc transporter
LQ335_RS10305	COG3781	membrane
LQ335_RS10310	COG2204	response regulator
LQ335_RS10315	COG4191	Histidine kinase
LQ335_RS10320	COG0484	heat shock protein binding
LQ335_RS10345	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LQ335_RS10350	COG1764	response to oxidative stress
LQ335_RS10370	COG2197	response regulator
LQ335_RS10375	COG2197	response regulator
LQ335_RS10400	COG3121	Chaperone
LQ335_RS10405	COG3188	usher protein
LQ335_RS10415	COG3121	Chaperone
LQ335_RS10445	COG3188	usher protein
LQ335_RS10615	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LQ335_RS10625	COG0542	response to heat
LQ335_RS10630	COG0071	Belongs to the small heat shock protein (HSP20) family
LQ335_RS10660	COG0789	Transcriptional regulator
LQ335_RS10665	COG2608	mercury ion transmembrane transporter activity
LQ335_RS10670	COG2608	mercury ion transmembrane transporter activity
LQ335_RS10680	COG0789	Transcriptional regulator
LQ335_RS10700	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
LQ335_RS10705	COG4644	lycopene metabolic process
LQ335_RS10775	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LQ335_RS10840	COG2132	Multicopper oxidase
LQ335_RS10865	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
LQ335_RS10960	COG1902	pentaerythritol trinitrate reductase activity
LQ335_RS10975	COG1309	transcriptional regulator
LQ335_RS11070	COG0653	protein targeting
LQ335_RS11100	COG0745	RESPONSE REGULATOR receiver
LQ335_RS11105	COG2205	protein histidine kinase activity
LQ335_RS11115	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LQ335_RS11120	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LQ335_RS11130	COG1136	(ABC) transporter
LQ335_RS11130	COG0577	efflux transmembrane transporter activity
LQ335_RS11135	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LQ335_RS11165	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
LQ335_RS11170	COG1529	Aldehyde oxidase and xanthine dehydrogenase
LQ335_RS11175	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
LQ335_RS11180	COG2080	2 iron, 2 sulfur cluster binding
LQ335_RS11195	COG1309	transcriptional regulator
LQ335_RS11235	COG3685	Protein conserved in bacteria
LQ335_RS11240	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
LQ335_RS11260	COG3546	catalase activity
LQ335_RS11265	COG3685	Protein conserved in bacteria
LQ335_RS11295	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
LQ335_RS11315	COG1063	alcohol dehydrogenase
LQ335_RS11350	COG1609	Transcriptional regulator
LQ335_RS11355	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
LQ335_RS11355	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
LQ335_RS11360	COG1105	Belongs to the carbohydrate kinase PfkB family
LQ335_RS11365	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LQ335_RS11365	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LQ335_RS11385	COG2211	Major facilitator Superfamily
LQ335_RS11390	COG1472	Belongs to the glycosyl hydrolase 3 family
LQ335_RS11405	COG3661	Belongs to the glycosyl hydrolase 67 family
LQ335_RS11415	COG1472	Belongs to the glycosyl hydrolase 3 family
LQ335_RS11420	COG0477	Major facilitator Superfamily
LQ335_RS11430	COG1070	Carbohydrate kinase
LQ335_RS11455	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
LQ335_RS11480	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LQ335_RS11495	COG2828	Protein conserved in bacteria
LQ335_RS11500	COG0583	DNA-binding transcription factor activity
LQ335_RS11520	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
LQ335_RS11525	COG0583	DNA-binding transcription factor activity
LQ335_RS11575	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LQ335_RS11610	COG2204	response regulator
LQ335_RS11700	COG0708	Exodeoxyribonuclease III
LQ335_RS11710	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LQ335_RS11720	COG1028	Short-chain dehydrogenase reductase Sdr
LQ335_RS11730	COG3214	Protein conserved in bacteria
LQ335_RS11740	COG4774	siderophore transport
LQ335_RS11765	COG0671	phosphoesterase, PA-phosphatase related
LQ335_RS11795	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
LQ335_RS11800	COG1285	pathogenesis
LQ335_RS11805	COG4191	Histidine kinase
LQ335_RS11810	COG4566	intracellular signal transduction
LQ335_RS11860	COG0477	Major facilitator Superfamily
LQ335_RS11885	COG1136	(ABC) transporter
LQ335_RS11900	COG0583	DNA-binding transcription factor activity
LQ335_RS11905	COG0656	L-ascorbic acid biosynthetic process
LQ335_RS11930	COG1028	Short-chain dehydrogenase reductase Sdr
LQ335_RS11955	COG0642	Histidine kinase
LQ335_RS11960	COG3537	Alpha-1,2-mannosidase
LQ335_RS11980	COG0477	Major facilitator Superfamily
LQ335_RS12000	COG3920	Histidine kinase
LQ335_RS12000	COG2202	Pas domain
LQ335_RS12060	COG0811	peptide transport
LQ335_RS12185	COG0840	transmembrane signaling receptor activity
LQ335_RS12190	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
LQ335_RS12195	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
LQ335_RS12200	COG4149	molybdate abc transporter
LQ335_RS12205	COG0725	ABC transporter, periplasmic molybdate-binding protein
LQ335_RS12210	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LQ335_RS12220	COG0746	molybdenum cofactor guanylyltransferase activity
LQ335_RS12225	COG0314	molybdopterin synthase activity
LQ335_RS12235	COG0303	'Molybdopterin
LQ335_RS12240	COG0521	Mo-molybdopterin cofactor biosynthetic process
LQ335_RS12240	COG0315	cyclic pyranopterin monophosphate synthase activity
LQ335_RS12245	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
LQ335_RS12290	COG2207	Transcriptional regulator
LQ335_RS12305	COG1566	PFAM secretion protein HlyD family protein
LQ335_RS12325	COG2205	protein histidine kinase activity
LQ335_RS12335	COG2194	sulfuric ester hydrolase activity
LQ335_RS12355	COG2885	chlorophyll binding
LQ335_RS12365	COG1028	Short-chain dehydrogenase reductase Sdr
LQ335_RS12370	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
LQ335_RS12370	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LQ335_RS12375	COG1535	isochorismatase
LQ335_RS12375	COG3433	isochorismatase activity
LQ335_RS12380	COG3433	isochorismatase activity
LQ335_RS12380	COG1535	isochorismatase
LQ335_RS12385	COG1021	2,3-dihydroxybenzoate-AMP ligase
LQ335_RS12400	COG2409	Drug exporters of the RND superfamily
LQ335_RS12405	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LQ335_RS12450	COG4771	TonB-dependent receptor
LQ335_RS12465	COG1914	H( )-stimulated, divalent metal cation uptake system
LQ335_RS12480	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LQ335_RS12485	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LQ335_RS12490	COG0604	alcohol dehydrogenase
LQ335_RS12490	COG1028	Short-chain dehydrogenase reductase Sdr
LQ335_RS12490	COG3321	synthase
LQ335_RS12500	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
LQ335_RS12520	COG0583	DNA-binding transcription factor activity
LQ335_RS12530	COG4772	TonB-dependent receptor
LQ335_RS12550	COG2226	methyltransferase
LQ335_RS12600	COG4964	Belongs to the GSP D family
LQ335_RS12655	COG2814	Major facilitator Superfamily
LQ335_RS12665	COG1228	amidohydrolase
LQ335_RS12675	COG1335	isochorismatase
LQ335_RS12690	COG3850	Histidine kinase
LQ335_RS12695	COG2197	response regulator
LQ335_RS12700	COG2814	Major facilitator Superfamily
LQ335_RS12710	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
LQ335_RS12720	COG0583	DNA-binding transcription factor activity
LQ335_RS12735	COG3161	chorismate lyase activity
LQ335_RS12750	COG2134	cdp-diacylglycerol pyrophosphatase
LQ335_RS12770	COG0277	FAD linked oxidase domain protein
LQ335_RS12775	COG1304	FMN binding
LQ335_RS12780	COG2186	Transcriptional regulator
LQ335_RS12795	COG1285	pathogenesis
LQ335_RS12820	COG2814	Major facilitator Superfamily
LQ335_RS12875	COG0587	DNA-directed DNA polymerase activity
LQ335_RS12890	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
LQ335_RS12895	COG0519	Catalyzes the synthesis of GMP from XMP
LQ335_RS12895	COG0518	GMP synthase (glutamine-hydrolyzing) activity
LQ335_RS12910	COG1595	DNA-templated transcription, initiation
LQ335_RS12920	COG4206	TonB-dependent receptor
LQ335_RS12920	COG1629	transport
LQ335_RS12945	COG0531	amino acid
LQ335_RS12960	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LQ335_RS12965	COG2207	Transcriptional regulator
LQ335_RS12965	COG1917	Cupin 2, conserved barrel domain protein
LQ335_RS12970	COG0789	Transcriptional regulator
LQ335_RS13050	COG3447	MASE1 domain protein
LQ335_RS13050	COG5002	protein histidine kinase activity
LQ335_RS13050	COG5001	Diguanylate cyclase
LQ335_RS13055	COG2183	response to ionizing radiation
LQ335_RS13085	COG3243	poly(R)-hydroxyalkanoic acid synthase
LQ335_RS13100	COG0534	Mate efflux family protein
LQ335_RS13120	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
LQ335_RS13135	COG0668	transmembrane transport
LQ335_RS13140	COG1902	pentaerythritol trinitrate reductase activity
LQ335_RS13150	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
LQ335_RS13160	COG1733	regulation of RNA biosynthetic process
LQ335_RS13165	COG2249	NAD(P)H dehydrogenase (quinone) activity
LQ335_RS13170	COG0456	acetyltransferase
LQ335_RS13270	COG3702	type iv secretory pathway
LQ335_RS13290	COG2948	multi-organism process
LQ335_RS13300	COG3736	Type IV secretory pathway, component VirB8
LQ335_RS13325	COG2814	Major facilitator Superfamily
LQ335_RS13350	COG0784	Response regulator, receiver
LQ335_RS13350	COG4191	Histidine kinase
LQ335_RS13360	COG4774	siderophore transport
LQ335_RS13370	COG0210	DNA helicase
LQ335_RS13400	COG0583	DNA-binding transcription factor activity
LQ335_RS13405	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
LQ335_RS13415	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
LQ335_RS13430	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
LQ335_RS13435	COG0077	Prephenate dehydratase
LQ335_RS13435	COG1605	Chorismate mutase
LQ335_RS13440	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
LQ335_RS13475	COG1228	amidohydrolase
LQ335_RS13490	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
LQ335_RS13535	COG2957	Belongs to the agmatine deiminase family
LQ335_RS13565	COG1136	(ABC) transporter
LQ335_RS13565	COG0577	efflux transmembrane transporter activity
LQ335_RS13610	COG4993	Dehydrogenase
LQ335_RS13620	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
LQ335_RS13630	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
LQ335_RS13640	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
LQ335_RS13645	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
LQ335_RS13660	COG0359	binds to the 23S rRNA
LQ335_RS13665	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
LQ335_RS13670	COG0360	Binds together with S18 to 16S ribosomal RNA
LQ335_RS13675	COG0316	Belongs to the HesB IscA family
LQ335_RS13680	COG0017	Asparaginyl-tRNA synthetase
LQ335_RS13700	COG0288	reversible hydration of carbon dioxide
LQ335_RS13710	COG3844	kynureninase activity
LQ335_RS13715	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LQ335_RS13720	COG2925	Exonuclease
LQ335_RS13730	COG0667	Aldo Keto reductase
LQ335_RS13755	COG2902	Dehydrogenase
LQ335_RS13765	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LQ335_RS13770	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LQ335_RS13780	COG1960	acyl-CoA dehydrogenase activity
LQ335_RS13795	COG0646	methionine synthase
LQ335_RS13795	COG1410	methionine synthase
LQ335_RS13810	COG2900	Belongs to the SlyX family
LQ335_RS13825	COG0386	Belongs to the glutathione peroxidase family
LQ335_RS13830	COG1725	Transcriptional regulator
LQ335_RS13835	COG1131	(ABC) transporter
LQ335_RS13860	COG0114	fumarate hydratase activity
LQ335_RS13885	COG2850	peptidyl-arginine hydroxylation
LQ335_RS13890	COG0456	acetyltransferase
LQ335_RS13895	COG0567	Dehydrogenase, E1 component
LQ335_RS13920	COG0305	Participates in initiation and elongation during chromosome replication
LQ335_RS13930	COG0367	asparagine synthase
LQ335_RS13940	COG0625	glutathione transferase activity
LQ335_RS13960	COG0084	hydrolase, TatD family'
LQ335_RS13965	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
LQ335_RS14000	COG0625	glutathione transferase activity
LQ335_RS14015	COG1595	DNA-templated transcription, initiation
LQ335_RS14020	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
LQ335_RS14035	COG0386	Belongs to the glutathione peroxidase family
LQ335_RS14040	COG0339	signal peptide processing
LQ335_RS14045	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
LQ335_RS14065	COG0705	Rhomboid family
LQ335_RS14070	COG3104	oligopeptide transport
LQ335_RS14080	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
LQ335_RS14085	COG4290	ribonuclease
LQ335_RS14100	COG0316	Belongs to the HesB IscA family
LQ335_RS14100	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
LQ335_RS14105	COG2154	pterin-4-alpha-carbinolamine dehydratase
LQ335_RS14115	COG0428	transporter
LQ335_RS14125	COG1530	ribonuclease E activity
LQ335_RS14140	COG0395	ABC-type sugar transport system, permease component
LQ335_RS14165	COG1609	Transcriptional regulator
LQ335_RS14170	COG0271	Belongs to the BolA IbaG family
LQ335_RS14175	COG2350	Protein conserved in bacteria
LQ335_RS14180	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
LQ335_RS14185	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
LQ335_RS14190	COG1187	pseudouridine synthase activity
LQ335_RS14200	COG2814	Major facilitator Superfamily
LQ335_RS14220	COG0436	Aminotransferase
LQ335_RS14225	COG4133	protoheme IX ABC transporter activity
LQ335_RS14245	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
LQ335_RS14250	COG1138	Cytochrome C-type biogenesis protein
LQ335_RS14260	COG3088	subunit of a heme lyase
LQ335_RS14260	COG4235	cytochrome complex assembly
LQ335_RS14270	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
LQ335_RS14280	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
LQ335_RS14285	COG4988	ABC transporter
LQ335_RS14295	COG1294	oxidase, subunit
LQ335_RS14325	COG0726	polysaccharide deacetylase
LQ335_RS14325	COG1649	PFAM Uncharacterised BCR, COG1649
LQ335_RS14330	COG1215	transferase activity, transferring glycosyl groups
LQ335_RS14340	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
LQ335_RS14355	COG0165	Argininosuccinate lyase
LQ335_RS14360	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
LQ335_RS14370	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
LQ335_RS14375	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LQ335_RS14380	COG0137	argininosuccinate synthase activity
LQ335_RS14385	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
LQ335_RS14400	COG2166	iron-sulfur cluster assembly
LQ335_RS14420	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
LQ335_RS14440	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
LQ335_RS14445	COG0402	S-adenosylhomocysteine deaminase activity
LQ335_RS14450	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
LQ335_RS14455	COG1509	lysine 2,3-aminomutase activity
LQ335_RS14460	COG3300	MHYT domain
LQ335_RS14460	COG5001	Diguanylate cyclase
LQ335_RS14480	COG0501	Belongs to the peptidase M48B family
LQ335_RS14490	COG1028	Short-chain dehydrogenase reductase Sdr
LQ335_RS14510	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
LQ335_RS14515	COG0860	N-Acetylmuramoyl-L-alanine amidase
LQ335_RS14520	COG0802	atpase or kinase
LQ335_RS14525	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
LQ335_RS14525	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
LQ335_RS14530	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
LQ335_RS14535	COG1570	exodeoxyribonuclease VII activity
LQ335_RS14545	COG1262	PFAM Formylglycine-generating sulfatase enzyme
LQ335_RS14555	COG4771	TonB-dependent receptor
LQ335_RS14580	COG2169	Transcriptional regulator
LQ335_RS14580	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
LQ335_RS14585	COG2130	NADP-dependent
LQ335_RS14610	COG1960	acyl-CoA dehydrogenase activity
LQ335_RS14630	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
LQ335_RS14645	COG2197	response regulator
LQ335_RS14655	COG1162	GTPase activity
LQ335_RS14710	COG2076	Multidrug Resistance protein
LQ335_RS14715	COG5487	UPF0391 membrane protein
LQ335_RS14720	COG1280	lysine exporter protein (LysE YggA)
LQ335_RS14725	COG0740	serine-type endopeptidase activity
LQ335_RS14740	COG1794	racemase activity, acting on amino acids and derivatives
LQ335_RS14780	COG0776	regulation of translation
LQ335_RS14785	COG0072	phenylalanine-tRNA ligase activity
LQ335_RS14785	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LQ335_RS14790	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
LQ335_RS14795	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
LQ335_RS14800	COG0291	Belongs to the bacterial ribosomal protein bL35 family
LQ335_RS14805	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
LQ335_RS14810	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
LQ335_RS14840	COG1185	polyribonucleotide nucleotidyltransferase activity
LQ335_RS14845	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
LQ335_RS14855	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
LQ335_RS14860	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
LQ335_RS14865	COG0195	Participates in both transcription termination and antitermination
LQ335_RS14870	COG0779	Required for maturation of 30S ribosomal subunits
LQ335_RS14885	COG1007	ATP synthesis coupled electron transport
LQ335_RS14900	COG0713	ATP synthesis coupled electron transport
LQ335_RS14910	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LQ335_RS14915	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
LQ335_RS14930	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
LQ335_RS14935	COG0649	NAD binding
LQ335_RS14940	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LQ335_RS14945	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LQ335_RS14950	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LQ335_RS14965	COG0149	triose-phosphate isomerase activity
LQ335_RS14975	COG3119	arylsulfatase activity
LQ335_RS14980	COG0438	transferase activity, transferring glycosyl groups
LQ335_RS14985	COG0726	polysaccharide deacetylase
LQ335_RS14990	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LQ335_RS14995	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
LQ335_RS15000	COG0159	tryptophan synthase activity
LQ335_RS15010	COG0133	tryptophan synthase activity
LQ335_RS15045	COG0135	phosphoribosylanthranilate isomerase activity
LQ335_RS15050	COG0101	tRNA pseudouridine synthase activity
LQ335_RS15065	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
LQ335_RS15075	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
LQ335_RS15080	COG2890	protein-(glutamine-N5) methyltransferase activity
LQ335_RS15085	COG1999	signal sequence binding
LQ335_RS15090	COG0688	phosphatidylethanolamine metabolic process
LQ335_RS15105	COG0433	COG0433 Predicted ATPase
LQ335_RS15110	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
LQ335_RS15120	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
LQ335_RS15125	COG0412	Dienelactone hydrolase
LQ335_RS15140	COG0717	Belongs to the dCTP deaminase family
LQ335_RS15145	COG0489	protein tyrosine kinase activity
LQ335_RS15150	COG4771	TonB-dependent receptor
LQ335_RS15155	COG4771	TonB-dependent receptor
LQ335_RS15165	COG4771	TonB-dependent receptor
LQ335_RS15170	COG3590	peptidase
LQ335_RS15200	COG0697	spore germination
LQ335_RS15215	COG2311	Membrane
LQ335_RS15220	COG1047	Peptidyl-prolyl cis-trans
LQ335_RS15225	COG0791	NLP P60 protein
LQ335_RS15230	COG0791	NLP P60 protein
LQ335_RS15235	COG1301	dicarboxylic acid transport
LQ335_RS15255	COG1722	exodeoxyribonuclease VII activity
LQ335_RS15260	COG0142	geranyltranstransferase activity
LQ335_RS15270	COG0312	modulator of DNA gyrase
LQ335_RS15275	COG3028	Belongs to the UPF0307 family
LQ335_RS15280	COG0312	modulator of DNA gyrase
LQ335_RS15300	COG2968	Membrane
LQ335_RS15325	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
LQ335_RS15335	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
LQ335_RS15350	COG0495	leucyl-tRNA aminoacylation
LQ335_RS15365	COG3118	belongs to the thioredoxin family
LQ335_RS15375	COG2203	Gaf domain
LQ335_RS15375	COG3706	GGDEF domain
LQ335_RS15375	COG4251	negative regulation of phosphorylation
LQ335_RS15375	COG5001	Diguanylate cyclase
LQ335_RS15395	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
LQ335_RS15405	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
LQ335_RS15410	COG0346	lactoylglutathione lyase activity
LQ335_RS15420	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LQ335_RS15420	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LQ335_RS15430	COG2878	Part of a membrane complex involved in electron transport
LQ335_RS15435	COG0251	oxidation-reduction process
LQ335_RS15440	COG0392	lysyltransferase activity
LQ335_RS15440	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
LQ335_RS15470	COG2824	Alkylphosphonate utilization operon protein PhnA
LQ335_RS15475	COG0443	Heat shock 70 kDa protein
LQ335_RS15515	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
LQ335_RS15520	COG3122	Protein conserved in bacteria
LQ335_RS15525	COG1451	nucleotide metabolic process
LQ335_RS15535	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LQ335_RS15555	COG0183	Belongs to the thiolase family
LQ335_RS15570	COG1960	acyl-CoA dehydrogenase activity
LQ335_RS15580	COG1793	dna ligase
LQ335_RS15585	COG1201	RNA secondary structure unwinding
LQ335_RS15600	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LQ335_RS15605	COG1278	Cold shock
LQ335_RS15610	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
LQ335_RS15615	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
LQ335_RS15620	COG1472	Belongs to the glycosyl hydrolase 3 family
LQ335_RS15625	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
LQ335_RS15630	COG2954	triphosphatase activity
LQ335_RS15635	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LQ335_RS15640	COG0745	RESPONSE REGULATOR receiver
LQ335_RS15655	COG1381	Involved in DNA repair and RecF pathway recombination
LQ335_RS15660	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
LQ335_RS15675	COG0681	Belongs to the peptidase S26 family
LQ335_RS15680	COG0481	GTPase activity
LQ335_RS15685	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LQ335_RS15700	COG1024	Enoyl-CoA hydratase
LQ335_RS15700	COG1250	3-hydroxyacyl-CoA dehydrogenase
LQ335_RS15705	COG1741	Belongs to the pirin family
LQ335_RS15710	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
LQ335_RS15720	COG1741	Belongs to the pirin family
LQ335_RS15725	COG1966	Carbon starvation protein
LQ335_RS15730	COG2879	small protein
LQ335_RS15740	COG2205	protein histidine kinase activity
LQ335_RS15745	COG0745	RESPONSE REGULATOR receiver
LQ335_RS15780	COG2814	Major facilitator Superfamily
LQ335_RS15785	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
LQ335_RS15785	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
LQ335_RS15795	COG1113	amino acid transport
LQ335_RS15800	COG1917	Cupin 2, conserved barrel domain protein
LQ335_RS15800	COG2207	Transcriptional regulator
LQ335_RS15805	COG0753	catalase activity
LQ335_RS15840	COG1376	ErfK ybiS ycfS ynhG family protein
LQ335_RS15845	COG0739	heme binding
LQ335_RS15855	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
LQ335_RS15865	COG0330	HflC and HflK could
LQ335_RS15870	COG0330	HflC and HflK could
LQ335_RS15875	COG0604	alcohol dehydrogenase
LQ335_RS15890	COG0678	peroxiredoxin activity
LQ335_RS15900	COG4953	penicillin-binding protein 1C
LQ335_RS15905	COG2373	Large extracellular alpha-helical protein
LQ335_RS15910	COG2079	MmgE PrpD family protein
LQ335_RS15915	COG2828	Protein conserved in bacteria
LQ335_RS15925	COG3609	addiction module antidote protein, CC2985 family
LQ335_RS15970	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
LQ335_RS15990	COG0477	Major facilitator Superfamily
LQ335_RS16010	COG3038	cytochrome b561
LQ335_RS16025	COG1760	l-serine dehydratase
LQ335_RS16030	COG1404	Belongs to the peptidase S8 family
LQ335_RS16040	COG0745	RESPONSE REGULATOR receiver
LQ335_RS16050	COG0460	homoserine dehydrogenase
LQ335_RS16050	COG0527	aspartate kinase activity
LQ335_RS16055	COG0626	cystathionine gamma-synthase activity
LQ335_RS16060	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
LQ335_RS16065	COG0739	heme binding
LQ335_RS16070	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
LQ335_RS16075	COG1272	protein, Hemolysin III
LQ335_RS16080	COG2982	Protein involved in outer membrane biogenesis
LQ335_RS16095	COG0463	Glycosyl transferase, family 2
LQ335_RS16100	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LQ335_RS16105	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
LQ335_RS16120	COG1309	transcriptional regulator
LQ335_RS16130	COG1960	acyl-CoA dehydrogenase activity
LQ335_RS16160	COG0583	DNA-binding transcription factor activity
LQ335_RS16175	COG0509	glycine decarboxylation via glycine cleavage system
LQ335_RS16180	COG0404	The glycine cleavage system catalyzes the degradation of glycine
LQ335_RS16190	COG0330	HflC and HflK could
LQ335_RS16200	COG1742	UPF0060 membrane protein
LQ335_RS16205	COG3956	TIGRFAM MazG family protein
LQ335_RS16210	COG1218	3'(2'),5'-bisphosphate nucleotidase
LQ335_RS16215	COG0494	nUDIX hydrolase
LQ335_RS16225	COG1385	rRNA (uridine-N3-)-methyltransferase activity
LQ335_RS16240	COG2198	Histidine kinase
LQ335_RS16240	COG0643	Histidine kinase
LQ335_RS16240	COG0784	Response regulator, receiver
LQ335_RS16245	COG0840	transmembrane signaling receptor activity
LQ335_RS16250	COG0835	chemotaxis
LQ335_RS16265	COG0189	ligase activity
LQ335_RS16290	COG1199	ATP-dependent helicase activity
LQ335_RS16300	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LQ335_RS16305	COG0463	Glycosyl transferase, family 2
LQ335_RS16315	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LQ335_RS16325	COG1643	Atp-dependent helicase
LQ335_RS16330	COG0783	Belongs to the Dps family
LQ335_RS16335	COG0514	ATP-dependent DNA helicase (RecQ)
LQ335_RS16420	COG3549	Plasmid maintenance system killer
LQ335_RS16445	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
LQ335_RS16450	COG0602	queuosine metabolic process
LQ335_RS16460	COG2885	chlorophyll binding
LQ335_RS16465	COG0823	Involved in the tonB-independent uptake of proteins
LQ335_RS16480	COG0811	peptide transport
LQ335_RS16485	COG0824	Thioesterase
LQ335_RS16490	COG2255	four-way junction helicase activity
LQ335_RS16500	COG0632	four-way junction helicase activity
LQ335_RS16505	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
LQ335_RS16510	COG0217	transcriptional regulatory protein
LQ335_RS16530	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
LQ335_RS16565	COG0488	(ABC) transporter
LQ335_RS16575	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
LQ335_RS16575	COG4651	solute:proton antiporter activity
LQ335_RS16585	COG0745	RESPONSE REGULATOR receiver
LQ335_RS16590	COG2205	protein histidine kinase activity
LQ335_RS16605	COG0542	response to heat
LQ335_RS16625	COG0028	Belongs to the TPP enzyme family
LQ335_RS16650	COG3387	PFAM Glycoside hydrolase 15-related
LQ335_RS16655	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
LQ335_RS16660	COG3011	Protein conserved in bacteria
LQ335_RS16675	COG0564	pseudouridine synthase activity
LQ335_RS16680	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LQ335_RS16690	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
LQ335_RS16690	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LQ335_RS16695	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
LQ335_RS16700	COG0045	succinate-CoA ligase (ADP-forming) activity
LQ335_RS16735	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
LQ335_RS16760	COG0745	RESPONSE REGULATOR receiver
LQ335_RS16780	COG0189	ligase activity
LQ335_RS16805	COG3240	lipase activity
LQ335_RS16805	COG4625	pathogenesis
LQ335_RS16815	COG2022	thiamine diphosphate biosynthetic process
LQ335_RS16820	COG0220	tRNA (guanine-N7-)-methyltransferase activity
LQ335_RS16825	COG0471	metal ion transport
LQ335_RS16825	COG3273	potassium ion transport
LQ335_RS16845	COG1970	mechanosensitive ion channel activity
LQ335_RS16855	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LQ335_RS16860	COG1115	amino acid carrier protein
LQ335_RS16870	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LQ335_RS16875	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LQ335_RS16900	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
LQ335_RS16910	COG3588	fructose-bisphosphate aldolase
LQ335_RS16915	COG0469	pyruvate kinase activity
LQ335_RS16925	COG0126	phosphoglycerate kinase activity
LQ335_RS16940	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
LQ335_RS16990	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
LQ335_RS17000	COG1301	dicarboxylic acid transport
LQ335_RS17030	COG0714	Associated with various cellular activities
LQ335_RS17060	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
LQ335_RS17100	COG3111	PFAM Bacterial OB fold (BOF) protein
LQ335_RS17110	COG0254	rRNA binding
LQ335_RS17125	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
LQ335_RS17135	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LQ335_RS17140	COG1758	RNA polymerase activity
LQ335_RS17155	COG0437	4 iron, 4 sulfur cluster binding
LQ335_RS17160	COG2864	formate dehydrogenase
LQ335_RS17175	COG1921	L-seryl-tRNASec selenium transferase activity
LQ335_RS17180	COG3276	selenocysteine insertion sequence binding
LQ335_RS17190	COG0709	Synthesizes selenophosphate from selenide and ATP
LQ335_RS17195	COG1561	YicC-like family, N-terminal region
LQ335_RS17200	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
LQ335_RS17205	COG0346	lactoylglutathione lyase activity
LQ335_RS17215	COG0635	Involved in the biosynthesis of porphyrin-containing compound
LQ335_RS17230	COG0006	proline dipeptidase activity
LQ335_RS17235	COG0006	proline dipeptidase activity
LQ335_RS17240	COG3079	Belongs to the UPF0149 family
LQ335_RS17260	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
LQ335_RS17270	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
LQ335_RS17280	COG2912	Transglutaminase-like superfamily
LQ335_RS17285	COG1773	rubredoxin
LQ335_RS17295	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
LQ335_RS17300	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
LQ335_RS17310	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
LQ335_RS17315	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LQ335_RS17330	COG1028	Short-chain dehydrogenase reductase Sdr
LQ335_RS17350	COG0671	phosphoesterase, PA-phosphatase related
LQ335_RS17360	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
LQ335_RS17365	COG0563	adenylate kinase activity
LQ335_RS17385	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
LQ335_RS17390	COG2832	Protein of unknown function (DUF454)
LQ335_RS17430	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
LQ335_RS17455	COG0745	RESPONSE REGULATOR receiver
LQ335_RS17465	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
LQ335_RS17470	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
LQ335_RS17480	COG0405	Gamma-glutamyltransferase
LQ335_RS17485	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
LQ335_RS17505	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
LQ335_RS17510	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
LQ335_RS17525	COG0473	3-isopropylmalate dehydrogenase activity
LQ335_RS17540	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LQ335_RS17545	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LQ335_RS17555	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
LQ335_RS17560	COG1538	Outer membrane efflux protein
LQ335_RS17565	COG0531	amino acid
LQ335_RS17570	COG1519	Transferase
LQ335_RS17575	COG1560	Kdo2-lipid A biosynthetic process
LQ335_RS17610	COG1301	dicarboxylic acid transport
LQ335_RS17620	COG4191	Histidine kinase
LQ335_RS17635	COG0642	Histidine kinase
LQ335_RS17650	COG2851	Citrate transporter
LQ335_RS17655	COG1028	Short-chain dehydrogenase reductase Sdr
LQ335_RS17675	COG1162	GTPase activity
LQ335_RS17680	COG0436	Aminotransferase
LQ335_RS17700	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
LQ335_RS17715	COG1228	amidohydrolase
LQ335_RS17720	COG0804	urea catabolic process
LQ335_RS17730	COG1307	EDD domain protein, DegV family
LQ335_RS17740	COG4251	negative regulation of phosphorylation
LQ335_RS17740	COG2203	Gaf domain
LQ335_RS17740	COG3706	GGDEF domain
LQ335_RS17740	COG5001	Diguanylate cyclase
LQ335_RS17755	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
LQ335_RS17775	COG1902	pentaerythritol trinitrate reductase activity
LQ335_RS17790	COG0583	DNA-binding transcription factor activity
LQ335_RS17795	COG1064	alcohol dehydrogenase
LQ335_RS17815	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
LQ335_RS17820	COG0218	Necessary for normal cell division and for the maintenance of normal septation
LQ335_RS17830	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
LQ335_RS17835	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
LQ335_RS17850	COG1522	sequence-specific DNA binding
LQ335_RS17860	COG4773	Receptor
LQ335_RS17890	COG0617	tRNA 3'-terminal CCA addition
LQ335_RS17925	COG3468	outer membrane autotransporter barrel domain protein
LQ335_RS17935	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
LQ335_RS17940	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
LQ335_RS17945	COG1609	Transcriptional regulator
LQ335_RS17955	COG0837	glucose binding
LQ335_RS17965	COG3525	Glycosyl hydrolase, family 20, catalytic domain
LQ335_RS17985	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
LQ335_RS17995	COG4191	Histidine kinase
LQ335_RS18000	COG0784	Response regulator, receiver
LQ335_RS18005	COG4251	negative regulation of phosphorylation
LQ335_RS18010	COG2823	Periplasmic or secreted lipoprotein
LQ335_RS18015	COG0673	inositol 2-dehydrogenase activity
LQ335_RS18020	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
LQ335_RS18040	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
LQ335_RS18045	COG0321	lipoyl(octanoyl) transferase activity
LQ335_RS18050	COG2921	Belongs to the UPF0250 family
LQ335_RS18060	COG1686	Belongs to the peptidase S11 family
LQ335_RS18070	COG2951	lytic endotransglycosylase activity
LQ335_RS18075	COG0772	Belongs to the SEDS family
LQ335_RS18080	COG0772	Belongs to the SEDS family
LQ335_RS18095	COG1792	Involved in formation and maintenance of cell shape
LQ335_RS18100	COG1077	Cell shape determining protein MreB Mrl
LQ335_RS18105	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LQ335_RS18120	COG0308	aminopeptidase N
LQ335_RS18125	COG2226	methyltransferase
LQ335_RS18160	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LQ335_RS18165	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LQ335_RS18175	COG0673	inositol 2-dehydrogenase activity
LQ335_RS18185	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
LQ335_RS18200	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
LQ335_RS18210	COG2832	Protein of unknown function (DUF454)
LQ335_RS18220	COG0436	Aminotransferase
LQ335_RS18225	COG1505	serine-type exopeptidase activity
LQ335_RS18260	COG0697	spore germination
LQ335_RS18265	COG1666	GTP binding
LQ335_RS18280	COG0339	signal peptide processing
LQ335_RS18290	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
LQ335_RS18330	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
LQ335_RS18340	COG1136	(ABC) transporter
LQ335_RS18345	COG0577	efflux transmembrane transporter activity
LQ335_RS18345	COG1136	(ABC) transporter
LQ335_RS18350	COG0577	efflux transmembrane transporter activity
LQ335_RS18365	COG4191	Histidine kinase
LQ335_RS18375	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
LQ335_RS18385	COG0355	proton-transporting ATP synthase activity, rotational mechanism
LQ335_RS18390	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
LQ335_RS18395	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
LQ335_RS18400	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
LQ335_RS18405	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
LQ335_RS18410	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
LQ335_RS18420	COG0356	it plays a direct role in the translocation of protons across the membrane
LQ335_RS18435	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LQ335_RS18440	COG0508	dehydrogenase complex catalyzes the overall conversion of
LQ335_RS18460	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
LQ335_RS18485	COG0181	hydroxymethylbilane synthase activity
LQ335_RS18495	COG2972	Histidine kinase
LQ335_RS18495	COG0745	RESPONSE REGULATOR receiver
LQ335_RS18510	COG4771	TonB-dependent receptor
LQ335_RS18525	COG0840	transmembrane signaling receptor activity
LQ335_RS18570	COG0625	glutathione transferase activity
LQ335_RS18585	COG2259	Doxx family
LQ335_RS18605	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LQ335_RS18655	COG1196	nuclear chromosome segregation
LQ335_RS18935	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LQ335_RS18940	COG1490	D-aminoacyl-tRNA deacylase activity
LQ335_RS18980	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
LQ335_RS18985	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
LQ335_RS18985	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
LQ335_RS18990	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
LQ335_RS18995	COG0242	peptide deformylase activity
LQ335_RS19005	COG0758	DNA mediated transformation
LQ335_RS19010	COG2922	Belongs to the Smg family
LQ335_RS19020	COG1714	RDD family
LQ335_RS19025	COG1754	DNA topoisomerase type I activity
LQ335_RS19025	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
LQ335_RS19030	COG0009	L-threonylcarbamoyladenylate synthase
LQ335_RS19045	COG1028	Short-chain dehydrogenase reductase Sdr
LQ335_RS19055	COG0616	signal peptide processing
LQ335_RS19060	COG0534	Mate efflux family protein
LQ335_RS19075	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
LQ335_RS19080	COG0625	glutathione transferase activity
LQ335_RS19090	COG1252	NADH dehydrogenase
LQ335_RS19105	COG2860	membrane
LQ335_RS19110	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
LQ335_RS19125	COG1846	Transcriptional regulator
LQ335_RS19155	COG0459	protein refolding
LQ335_RS19160	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
LQ335_RS19165	COG2356	endonuclease I
LQ335_RS19170	COG1324	tolerance protein
LQ335_RS19180	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LQ335_RS19200	COG0840	transmembrane signaling receptor activity
LQ335_RS19215	COG0583	DNA-binding transcription factor activity
LQ335_RS19230	COG1686	Belongs to the peptidase S11 family
LQ335_RS19240	COG2249	NAD(P)H dehydrogenase (quinone) activity
LQ335_RS19250	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
LQ335_RS19260	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
LQ335_RS19265	COG0511	ligase activity, forming carbon-carbon bonds
LQ335_RS19270	COG0439	Biotin carboxylase
LQ335_RS19285	COG2264	protein methyltransferase activity
LQ335_RS19295	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
LQ335_RS19300	COG4589	Belongs to the CDS family
LQ335_RS19305	COG0204	Acyl-transferase
LQ335_RS19315	COG2453	phosphatase
LQ335_RS19315	COG0671	phosphoesterase, PA-phosphatase related
LQ335_RS19320	COG2267	carboxylic ester hydrolase activity
LQ335_RS19325	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
LQ335_RS19330	COG0138	bifunctional purine biosynthesis protein purh
LQ335_RS19335	COG0151	Belongs to the GarS family
LQ335_RS19350	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LQ335_RS19355	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
LQ335_RS19360	COG2201	protein-glutamate methylesterase activity
LQ335_RS19365	COG2177	Part of the ABC transporter FtsEX involved in
LQ335_RS19370	COG2884	Cell division ATP-binding protein ftsE
LQ335_RS19375	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
LQ335_RS19385	COG3118	belongs to the thioredoxin family
LQ335_RS19390	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
LQ335_RS19395	COG3706	GGDEF domain
LQ335_RS19405	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
LQ335_RS19445	COG1652	LysM domain
LQ335_RS19450	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
LQ335_RS19450	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
LQ335_RS19455	COG1473	amidohydrolase
LQ335_RS19460	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LQ335_RS19465	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LQ335_RS19470	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LQ335_RS19475	COG1289	transmembrane transporter activity
LQ335_RS19480	COG1028	Short-chain dehydrogenase reductase Sdr
LQ335_RS19485	COG2814	Major facilitator Superfamily
LQ335_RS19515	COG0316	Belongs to the HesB IscA family
LQ335_RS19555	COG1051	belongs to the nudix hydrolase family
LQ335_RS19570	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
LQ335_RS19575	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
LQ335_RS19580	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
LQ335_RS19590	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
LQ335_RS19595	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LQ335_RS19600	COG0730	response to heat
LQ335_RS19610	COG0134	indole-3-glycerol-phosphate synthase activity
LQ335_RS19615	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
LQ335_RS19635	COG1597	lipid kinase activity
LQ335_RS19650	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
LQ335_RS19655	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
LQ335_RS19665	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
LQ335_RS19665	COG2111	Na H antiporter
LQ335_RS19670	COG1006	Multisubunit Na H antiporter MnhC subunit
LQ335_RS19675	COG0651	ATP synthesis coupled electron transport
LQ335_RS19680	COG1863	multisubunit Na H antiporter MnhE subunit
LQ335_RS19685	COG2212	antiporter activity
LQ335_RS19690	COG1320	monovalent cation:proton antiporter activity
LQ335_RS19695	COG0530	calcium, potassium:sodium antiporter activity
LQ335_RS19710	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
LQ335_RS19735	COG3104	oligopeptide transport
LQ335_RS19740	COG3483	tryptophan 2,3-dioxygenase activity
LQ335_RS19775	COG2378	regulation of single-species biofilm formation
LQ335_RS19790	COG2354	Protein conserved in bacteria
LQ335_RS19805	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
LQ335_RS19805	COG3264	Mechanosensitive ion channel
LQ335_RS19820	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
LQ335_RS19855	COG1166	arginine decarboxylase activity
LQ335_RS19860	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
LQ335_RS19890	COG2960	long-chain fatty acid transporting porin activity
LQ335_RS19940	COG0606	chelatase, subunit chli
LQ335_RS19965	COG3932	Exopolysaccharide synthesis, ExoD
LQ335_RS19995	COG1999	signal sequence binding
LQ335_RS20000	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
LQ335_RS20005	COG1845	cytochrome c oxidase, subunit III
LQ335_RS20015	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
LQ335_RS20020	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LQ335_RS20035	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LQ335_RS20065	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
LQ335_RS20070	COG3409	Peptidoglycan-binding domain 1 protein
LQ335_RS20070	COG0860	N-Acetylmuramoyl-L-alanine amidase
LQ335_RS20095	COG2031	fatty acid transporter
LQ335_RS20145	COG0673	inositol 2-dehydrogenase activity
LQ335_RS20155	COG1501	Belongs to the glycosyl hydrolase 31 family
LQ335_RS20160	COG2222	sugar isomerase
LQ335_RS20165	COG1940	carbohydrate kinase activity
LQ335_RS20175	COG1349	DNA-binding transcription factor activity
LQ335_RS20180	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
LQ335_RS20185	COG2814	Major facilitator Superfamily
LQ335_RS20195	COG3210	domain, Protein
LQ335_RS20215	COG1040	competence protein
LQ335_RS20235	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
LQ335_RS20240	COG0156	8-amino-7-oxononanoate synthase activity
LQ335_RS20245	COG2267	carboxylic ester hydrolase activity
LQ335_RS20250	COG1028	Short-chain dehydrogenase reductase Sdr
LQ335_RS20265	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
LQ335_RS20285	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LQ335_RS20290	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LQ335_RS20295	COG2205	protein histidine kinase activity
LQ335_RS20300	COG0745	RESPONSE REGULATOR receiver
LQ335_RS20305	COG3541	Predicted nucleotidyltransferase
LQ335_RS20310	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
LQ335_RS20335	COG0714	Associated with various cellular activities
LQ335_RS20350	COG0754	glutathionylspermidine amidase activity
LQ335_RS20360	COG0129	dihydroxy-acid dehydratase activity
LQ335_RS20365	COG1199	ATP-dependent helicase activity
LQ335_RS20375	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
LQ335_RS20395	COG3781	membrane
LQ335_RS20425	COG0625	glutathione transferase activity
LQ335_RS20445	COG2207	Transcriptional regulator
LQ335_RS20460	COG4555	ABC transporter
LQ335_RS20485	COG0543	2 iron, 2 sulfur cluster binding
LQ335_RS20485	COG0633	Ferredoxin
LQ335_RS20490	COG1131	(ABC) transporter
LQ335_RS20495	COG0842	Transport permease protein
LQ335_RS20500	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
LQ335_RS20510	COG0084	hydrolase, TatD family'
LQ335_RS20515	COG1643	Atp-dependent helicase
LQ335_RS20525	COG1187	pseudouridine synthase activity
LQ335_RS20535	COG0667	Aldo Keto reductase
LQ335_RS20550	COG1690	Belongs to the RtcB family
LQ335_RS20575	COG2267	carboxylic ester hydrolase activity
LQ335_RS20580	COG0393	Putative heavy-metal-binding
LQ335_RS20585	COG0045	succinate-CoA ligase (ADP-forming) activity
LQ335_RS20585	COG1042	CoA-binding domain protein
LQ335_RS20585	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LQ335_RS20590	COG2239	Acts as a magnesium transporter
LQ335_RS20600	COG0666	response to abiotic stimulus
LQ335_RS20600	COG3177	Filamentation induced by cAMP protein fic
LQ335_RS20605	COG3100	YcgL domain-containing protein
LQ335_RS20615	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
LQ335_RS20620	COG1028	Short-chain dehydrogenase reductase Sdr
LQ335_RS20660	COG2986	histidine ammonia-lyase
LQ335_RS20670	COG0463	Glycosyl transferase, family 2
LQ335_RS20685	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LQ335_RS20690	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LQ335_RS20705	COG1294	oxidase, subunit
LQ335_RS20710	COG1271	oxidase subunit
LQ335_RS20720	COG1595	DNA-templated transcription, initiation
LQ335_RS20750	COG0408	coproporphyrinogen oxidase activity
LQ335_RS20770	COG0589	response to stress
LQ335_RS20785	COG0210	DNA helicase
LQ335_RS20795	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LQ335_RS20805	COG0267	Belongs to the bacterial ribosomal protein bL33 family
LQ335_RS20810	COG0227	Belongs to the bacterial ribosomal protein bL28 family
LQ335_RS20825	COG0251	oxidation-reduction process
LQ335_RS20860	COG0463	Glycosyl transferase, family 2
LQ335_RS20875	COG1475	DNA binding
LQ335_RS20880	COG1192	Involved in chromosome partitioning
LQ335_RS20885	COG0357	Ribosomal RNA small subunit methyltransferase G
LQ335_RS20890	COG2091	lysine biosynthetic process via aminoadipic acid
LQ335_RS20930	COG1943	Transposase
LQ335_RS20935	COG1971	Probably functions as a manganese efflux pump
LQ335_RS20950	COG2911	Protein conserved in bacteria
LQ335_RS20955	COG0729	surface antigen
LQ335_RS20965	COG0752	glycyl-tRNA synthetase alpha subunit
LQ335_RS20970	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
LQ335_RS20975	COG0518	GMP synthase (glutamine-hydrolyzing) activity
LQ335_RS20975	COG0519	Catalyzes the synthesis of GMP from XMP
LQ335_RS20985	COG0805	protein transport
LQ335_RS20995	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
LQ335_RS21005	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
LQ335_RS21015	COG0840	transmembrane signaling receptor activity
LQ335_RS21025	COG1126	abc transporter atp-binding protein
LQ335_RS21035	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LQ335_RS21040	COG0577	efflux transmembrane transporter activity
LQ335_RS21040	COG1136	(ABC) transporter